PREFIX obo: <http://purl.obolibrary.org/obo/>
PREFIX rdf: <http://www.w3.org/1999/02/22-rdf-syntax-ns#>
PREFIX rdfs: <http://www.w3.org/2000/01/rdf-schema#>
PREFIX xsd: <http://www.w3.org/2001/XMLSchema#>

obo:OBIB_0000411 a rdfs:Class ;
  rdfs:label "presence of sarcomatoid features on specimen slide" ;
  rdfs:comment "An information content entity that is an indicator of whether examination of a tissue specimen slide revealed the presence of sarcomatoid features." ;
  rdfs:subClassOf obo:IAO_0000030 .

obo:RO_0000056 a rdf:Property ;
  rdfs:label "participates in"@en ;
  rdfs:comment "a relation between a continuant and a process, in which the continuant is somehow involved in the process"@en ;
  rdfs:domain obo:BFO_0000002 ;
  rdfs:range obo:BFO_0000003 .

obo:IAO_0020012 a rdf:Property ;
  rdfs:label "designates"@en ;
  rdfs:comment "x designates y, if for any given group of language users, x is an information content entity, is about y, and represents y in a linguistic context.."@en ;
  rdfs:domain obo:IAO_0000030 ;
  rdfs:range obo:BFO_0000001 , obo:NCBITaxon_9606 .

obo:RO_0000058 a rdf:Property ;
  rdfs:label "is concretized as"@en ;
  rdfs:comment "A relationship between a generically dependent continuant and a specifically dependent continuant, in which the generically dependent continuant depends on some independent continuant in virtue of the fact that the specifically dependent continuant also depends on that same independent continuant. A generically dependent continuant may be concretized as multiple specifically dependent continuants."@en ;
  rdfs:domain obo:BFO_0000031 ;
  rdfs:range obo:BFO_0000020 .

obo:OBIB_0000734 a rdf:Property ;
  rdfs:label "is contact information about"@en ;
  rdfs:comment "a is contact information for b, if a is a information content entity, b is a human being or an organization and a identifies a physical location or electronic resource that allows to initiate communication with a."@en ;
  rdfs:domain obo:IAO_0000030 ;
  rdfs:range <https://w3id.org/linkml/Any> ;
  rdfs:subPropertyOf obo:IAO_0000136 .

obo:OBIB_0000735 a rdf:Property ;
  rdfs:label "is owned by"@en ;
  rdfs:comment "a is owned by b if b has complete power over a. All rights and obligations of ownership are grounded in this (primitive) relation. The claims and obligations of ownership can be partially transferred to a third party by the owner, b."@en ;
  rdfs:range xsd:string .

obo:OBI_0000094 a rdfs:Class ;
  rdfs:label "material processing"@en ;
  rdfs:comment "A planned process which results in physical changes in a specified input material"@en ;
  rdfs:subClassOf obo:OBI_0000011 .

obo:OBI_0000299 a rdf:Property ;
  rdfs:label "has_specified_output"@en ;
  rdfs:comment "The inverse property of is_specified_output_of"@en ;
  rdfs:domain obo:BFO_0000003 ;
  rdfs:range obo:BFO_0000002 ;
  rdfs:subPropertyOf obo:RO_0000057 .

obo:BFO_0000066 a rdf:Property ;
  rdfs:label "occurs in"@en ;
  rdfs:comment "b occurs_in c =def b is a process and c is a material entity or immaterial entity& there exists a spatiotemporal region r and b occupies_spatiotemporal_region r.& forall(t) if b exists_at t then c exists_at t & there exist spatial regions s and s’ where & b spatially_projects_onto s at t& c is occupies_spatial_region s’ at t& s is a proper_continuant_part_of s’ at t"@en ;
  rdfs:domain obo:BFO_0000003 ;
  rdfs:range obo:BFO_0000004 .

obo:BFO_0000184 a rdf:Property ;
  rdfs:label "history of"@en ;
  rdfs:comment "[copied from inverse property 'has history'] b has_history c iff c history_of b [XXX-001" ;
  rdfs:domain obo:BFO_0000015 ;
  rdfs:range obo:BFO_0000040 ;
  rdfs:subPropertyOf obo:BFO_0000066 .

obo:OBI_0000417 a rdf:Property ;
  rdfs:label "achieves_planned_objective" ;
  rdfs:comment "This relation obtains between a planned process and a objective specification when the criteria specified in the objective specification are met at the end of the planned process." ;
  rdfs:range <https://w3id.org/linkml/Any> .

obo:OBI_0000293 a rdf:Property ;
  rdfs:label "has_specified_input"@en ;
  rdfs:comment "The inverse property of is_specified_input_of"@en ;
  rdfs:domain obo:BFO_0000003 ;
  rdfs:range obo:BFO_0000040 , obo:BFO_0000002 , obo:IAO_0000027 ;
  rdfs:subPropertyOf obo:RO_0000057 .

obo:BFO_0000055 a rdf:Property ;
  rdfs:label "realizes"@en ;
  rdfs:comment "Paraphrase of elucidation: a relation between a process and a realizable entity, where there is some material entity that is bearer of the realizable entity and participates in the process, and the realizable entity comes to be realized in the course of the process" ;
  rdfs:domain obo:BFO_0000015 ;
  rdfs:range obo:BFO_0000017 .

obo:RO_0000057 a rdf:Property ;
  rdfs:label "has participant"@en ;
  rdfs:comment "a relation between a process and a continuant, in which the continuant is somehow involved in the process"@en ;
  rdfs:domain obo:BFO_0000003 ;
  rdfs:range obo:BFO_0000002 .

obo:OMIABIS_0001036 a rdfs:Class ;
  rdfs:label "obsolete temperature regulating" ;
  rdfs:subClassOf <http://www.geneontology.org/formats/oboInOwl#ObsoleteClass> .

obo:OBIB_0000279 a rdfs:Class ;
  rdfs:label "name of person receiving specimen shipment" ;
  rdfs:comment "A personal name that designates the person who received the specimen that was transported from another organization." ;
  rdfs:subClassOf obo:IAO_0000027 .

obo:OBIB_0002002 a rdfs:Class ;
  rdfs:label "specimen weight"@en ;
  rdfs:comment "A mass measurement datum that is the result of an assay to measure the weight of a specimen." ;
  rdfs:subClassOf obo:IAO_0000414 .

obo:IAO_0000136 a rdf:Property ;
  rdfs:label "is about"@en ;
  rdfs:comment "A (currently) primitive relation that relates an information artifact to an entity."@en ;
  rdfs:range <https://w3id.org/linkml/Any> .

obo:PR_000009054 a rdfs:Class ;
  rdfs:label "insulin gene translation product" ;
  rdfs:comment "An insulin family protein that is a translation product of the human INS gene or a 1:1 ortholog thereof." ;
  rdfs:subClassOf obo:PR_000000001 .

obo:BFO_0000185 a rdf:Property ;
  rdfs:label "has history"@en ;
  rdfs:comment "b has_history c iff c history_of b [XXX-001"@en ;
  rdfs:domain obo:BFO_0000040 ;
  rdfs:range obo:BFO_0000015 ;
  rdfs:subPropertyOf obo:BFO_0000067 .

obo:RO_0000087 a rdf:Property ;
  rdfs:label "has role"@en ;
  rdfs:comment "a relation between an independent continuant (the bearer) and a role, in which the role specifically depends on the bearer for its existence"@en ;
  rdfs:domain obo:BFO_0000004 ;
  rdfs:range obo:BFO_0000023 ;
  rdfs:subPropertyOf obo:RO_0000053 .

obo:RO_0000085 a rdf:Property ;
  rdfs:label "has function"@en ;
  rdfs:comment "a relation between an independent continuant (the bearer) and a function, in which the function specifically depends on the bearer for its existence"@en ;
  rdfs:domain obo:BFO_0000004 ;
  rdfs:range obo:BFO_0000034 ;
  rdfs:subPropertyOf obo:RO_0000053 .

obo:RO_0000091 a rdf:Property ;
  rdfs:label "has disposition"@en ;
  rdfs:comment "a relation between an independent continuant (the bearer) and a disposition, in which the disposition specifically depends on the bearer for its existence"@en ;
  rdfs:domain obo:BFO_0000004 ;
  rdfs:range obo:BFO_0000016 ;
  rdfs:subPropertyOf obo:RO_0000053 .

obo:RO_0002002 a rdf:Property ;
  rdfs:label "has 2D boundary"@en ;
  rdfs:comment "a relation between a material entity and a 2D immaterial entity (the boundary), in which the boundary delimits the material entity"@en ;
  rdfs:domain obo:BFO_0000040 ;
  rdfs:range obo:BFO_0000141 .

obo:RO_0001025 a rdf:Property ;
  rdfs:label "located in"@en ;
  rdfs:comment "a relation between two independent continuants, the target and the location, in which the target is entirely within the location"@en ;
  rdfs:domain obo:BFO_0000004 ;
  rdfs:range <https://w3id.org/linkml/Any> .

obo:OBI_0002465 a rdfs:Class ;
  rdfs:label "age since culture seeding measurement datum" ;
  rdfs:comment "An age measurement datum that is the result of the measurement of the age of a cell since cultured (the process of seeding cells onto a culture dish)." ;
  rdfs:subClassOf obo:OBI_0001167 .

obo:IAO_0000221 a rdf:Property ;
  rdfs:label "is quality measurement of"@en ;
  rdfs:comment "m is a quality measurement of q at t. When q is a quality, there is a measurement process p that has specified output m, a measurement datum, that is about q"@en ;
  rdfs:range <https://w3id.org/linkml/Any> ;
  rdfs:subPropertyOf obo:IAO_0000136 .

obo:OBIB_0000219 a rdfs:Class ;
  rdfs:label "recycled buffered formalin condition" ;
  rdfs:comment "A buffered formalin condition by virtue of the formalin having undergone a recycling process such as fractional distillation by temperature." ;
  rdfs:subClassOf obo:OBIB_0000220 .

obo:RO_0000059 a rdf:Property ;
  rdfs:label "concretizes"@en ;
  rdfs:comment "A relationship between a specifically dependent continuant and a generically dependent continuant, in which the generically dependent continuant depends on some independent continuant in virtue of the fact that the specifically dependent continuant also depends on that same independent continuant. Multiple specifically dependent continuants can concretize the same generically dependent continuant."@en ;
  rdfs:domain obo:BFO_0000020 ;
  rdfs:range obo:BFO_0000031 .

obo:NCIT_C15675 a rdfs:Class ;
  rdfs:label "Adjuvant Therapy" ;
  rdfs:comment "Any therapy that is administered to augment or stimulate other treatment modalities or to minimize or prevent disease recurrence subsequent to the main treatment plan." ;
  rdfs:subClassOf obo:NCIT_C16212 .

obo:UBERON_0001161 a rdfs:Class ;
  rdfs:label "body of stomach" ;
  rdfs:comment "The body of stomach is the part of the stomach that lies between the fundus above and the pyloric antrum below; its boundaries are poorly defined[GO]." ;
  rdfs:subClassOf obo:UBERON_0000064 .

obo:OBIB_0000353 a rdfs:Class ;
  rdfs:label "data and time parent specimen ID was recorded" ;
  rdfs:comment "A data item indicating the date and time at which the parent specimen ID was recorded." ;
  rdfs:subClassOf obo:IAO_0000027 .

obo:OBI_0600044 a rdfs:Class ;
  rdfs:label "lavage"@en ;
  rdfs:comment "A protocol application to separate cells and/or cellular secretions from an anatomical space by the introduction and removal of fluid"@en ;
  rdfs:subClassOf obo:OBI_0600005 , obo:OBI_0600014 .

obo:IDO_0000619 a rdfs:Class ;
  rdfs:label "immunosuppressive disposition"@en ;
  rdfs:comment "A disposition whose realization negatively regulates an immune response."@en ;
  rdfs:subClassOf obo:BFO_0000016 .

obo:BFO_0000054 a rdf:Property ;
  rdfs:label "realized in"@en ;
  rdfs:comment "Paraphrase of elucidation: a relation between a realizable entity and a process, where there is some material entity that is bearer of the realizable entity and participates in the process, and the realizable entity comes to be realized in the course of the process" ;
  rdfs:domain obo:BFO_0000017 ;
  rdfs:range obo:BFO_0000015 , obo:OBI_0000011 , obo:OBI_0000066 , obo:OBIB_0000624 , obo:OBI_0001007 , obo:OBI_0000457 , obo:OBI_0000274 , obo:OBI_0000070 , obo:OBI_0000471 .

obo:OMIABIS_0001017 a rdfs:Class ;
  rdfs:label "obsolete case control study design" ;
  rdfs:subClassOf <http://www.geneontology.org/formats/oboInOwl#ObsoleteClass> .

obo:DOID_0050934 a rdfs:Class .

obo:OBIB_0000059 a rdfs:Class ;
  rdfs:label "Location adjacent to tissue fixation" ;
  rdfs:comment "An anatomical location that is adjacent to the site where tissue was collected and subjected to fixation." ;
  rdfs:subClassOf obo:FMA_50707 .

obo:OBIB_0000301 a rdfs:Class ;
  rdfs:label "FFPE clearing agent duration" ;
  rdfs:comment "A time measurement datum that is the result of measuring the duration in clearing agent in the formalin-fixed paraffin-embedded (FFPE) process." ;
  rdfs:subClassOf obo:IAO_0000416 .

obo:NCBITaxon_117571 a rdfs:Class ;
  rdfs:label "Euteleostomi" ;
  rdfs:subClassOf obo:NCBITaxon_7742 .

obo:OBIB_0000631 a rdfs:Class ;
  rdfs:label "department of biobank contact"@en ;
  rdfs:comment "A department that has a contact person for a biobank as an organizational member."@en ;
  rdfs:subClassOf obo:OBIB_0000630 .

obo:OBIB_0000733 a rdf:Property ;
  rdfs:label "administrates"@en ;
  rdfs:comment "a administrates b if c owns b and some rights and obligations grounded in the owning relation regarding b are transferred  from c to a."@en ;
  rdfs:range xsd:string .

obo:OBIB_0000732 a rdf:Property ;
  rdfs:label "owns"@en ;
  rdfs:range xsd:string .

obo:OBIB_0000177 a rdfs:Class ;
  rdfs:label "left radical nephrectomy" ;
  rdfs:comment "A surgical procedure to remove the entire left kidney." ;
  rdfs:subClassOf obo:OBIB_0000716 .

obo:FLU_0001019 a rdfs:Class ;
  rdfs:label "specimen barcode" ;
  rdfs:comment "A specimen barcode is a specimen identification number formatted as an optical machine-readable representation."@en ;
  rdfs:subClassOf obo:OBIB_0000721 .

obo:BFO_0000051 a rdf:Property ;
  rdfs:label "has part"@en ;
  rdfs:comment "a core relation that holds between a whole and its part"@en ;
  rdfs:range <https://w3id.org/linkml/Any> , obo:IAO_0000029 , obo:OBI_0100051 , obo:IAO_0000030 .

obo:OBI_0000312 a rdf:Property ;
  rdfs:label "is_specified_output_of"@en ;
  rdfs:comment "A relation between a planned process and a continuant participating in that process. The presence of the continuant at the end of the process is explicitly specified in the objective specification which the process realizes the concretization of."@en ;
  rdfs:domain obo:BFO_0000002 ;
  rdfs:range obo:IAO_0020010 , obo:BFO_0000003 , obo:OBI_0600044 , obo:OBIB_0000710 ;
  rdfs:subPropertyOf obo:RO_0000056 .

obo:OBIB_0000479 a rdfs:Class ;
  rdfs:label "date on which research authorization was obtained from legally authorized representative" ;
  rdfs:comment "A data item that indicates the calendar date on which a research authorization was obtained from a specimen donor's legally authorized representative." ;
  rdfs:subClassOf obo:IAO_0000027 .

obo:OBI_0002775 a rdfs:Class ;
  rdfs:label "platelet-poor plasma preparation process"@en ;
  rdfs:comment "A material component separation process in which (1) whole blood is first centrifuged to separate red blood cells from blood plasma, which forms the supernatant, and (2) the blood plasma is then centrifuged to separate platelets from the plasm."@en ;
  rdfs:subClassOf obo:OBI_0600014 .

obo:OBIB_0000025 a rdfs:Class ;
  rdfs:label "collection packet with empty container"@en ;
  rdfs:comment "A collection packet which contains an empty container that will be used for holding a specimen." ;
  rdfs:subClassOf obo:OBIB_0000028 .

<http://purl.obolibrary.org/obo/cl#lacks_part> a rdf:Property ;
  rdfs:label "lacks_part" ;
  rdfs:range <https://w3id.org/linkml/Any> .

obo:GEO_000000372 a rdfs:Class ;
  rdfs:label "geographical region"@en ;
  rdfs:comment "A geographical entity that is demarcated at least in part by one or more closed fiat boundaries all of whose lines are part of the planetary surface."@en ;
  rdfs:subClassOf obo:GEO_000000370 .

obo:OBIB_0000439 a rdfs:Class ;
  rdfs:label "follow-up on donor outcome comment from tissue procurement" ;
  rdfs:comment "A comment from tissue procurement that was submitted as part of a follow-up documenting donor outcome after initial specimen collection." ;
  rdfs:subClassOf obo:OBIB_0000712 .

obo:OBIB_0000043 a rdfs:Class ;
  rdfs:label "nicotine patch"@en ;
  rdfs:comment "A processed material that contains nicotine in the form of a transdermal patch which releases nicotine into the body through the skin. It is commonly used as an aid in nicotine replacement therapy (NRT), a process for smoking cessation." ;
  rdfs:subClassOf obo:OBIB_0000048 .

obo:OMIABIS_0000051 a rdfs:Class ;
  rdfs:label "obsolete fixed tissue block specimen" ;
  rdfs:subClassOf <http://www.geneontology.org/formats/oboInOwl#ObsoleteClass> .

obo:OBIB_0000381 a rdfs:Class ;
  rdfs:label "specimen was processed in accordance with the FFPE SOP" ;
  rdfs:comment "A specimen was processed in accordance with the specified SOP where the specified SOP is for a formalin-fixed paraffin-embedded (FFPE) process." ;
  rdfs:subClassOf obo:OBIB_0000259 .

obo:OBIB_0000036 a rdfs:Class ;
  rdfs:label "buffy coat specimen"@en ;
  rdfs:comment "A processed specimen which is the output of a density gradient centrifugation of an anticoagulated blood specimen that contains most of the white blood cells and platelets." ;
  rdfs:subClassOf obo:OBI_0000953 .

obo:OBI_0000655 a rdfs:Class ;
  rdfs:label "blood specimen" ;
  rdfs:comment "a material entity derived from a portion of blood collected from an organism" ;
  rdfs:subClassOf obo:OBI_2000009 .

obo:RO_0001000 a rdf:Property ;
  rdfs:label "derives from"@en ;
  rdfs:comment "a relation between two distinct material entities, the new entity and the old entity, in which the new entity begins to exist when the old entity ceases to exist, and the new entity inherits the significant portion of the matter of the old entity"@en ;
  rdfs:range <https://w3id.org/linkml/Any> .

obo:FMA_17181 a rdfs:Class ;
  rdfs:label "Wall of distal part of ileum" ;
  rdfs:subClassOf obo:UBERON_0000064 .

obo:OBIB_0000312 a rdfs:Class ;
  rdfs:label "age of paraffin" ;
  rdfs:comment "A scalar measurement datum that is the output of an age measurement assay performed on paraffin." ;
  rdfs:subClassOf obo:IAO_0000032 .

obo:BFO_0000034 a rdfs:Class ;
  rdfs:label "function"@en ;
  rdfs:subClassOf obo:BFO_0000016 .

obo:RO_0000079 a rdf:Property ;
  rdfs:label "function of"@en ;
  rdfs:comment "a relation between a function and an independent continuant (the bearer), in which the function specifically depends on the bearer for its existence"@en ;
  rdfs:domain obo:BFO_0000034 ;
  rdfs:range <https://w3id.org/linkml/Any> ;
  rdfs:subPropertyOf obo:RO_0000052 .

obo:FMA_37830 a rdfs:Class ;
  rdfs:label "Skin of left leg" ;
  rdfs:subClassOf obo:UBERON_0002097 .

obo:OBI_0002399 a rdfs:Class ;
  rdfs:label "unilateral oophorectomy history" ;
  rdfs:comment "A gynecologic surgery history in which a woman has had a unilateral oophorectomy." ;
  rdfs:subClassOf obo:OBI_0002397 .

obo:FMA_19972 a rdfs:Class ;
  rdfs:label "Anterior wall of vagina" ;
  rdfs:subClassOf obo:UBERON_0000064 .

obo:OBI_0000947 a rdfs:Class ;
  rdfs:label "service provider role" ;
  rdfs:comment "is a role which inheres in a person or organization and is realized in in a planned process which provides access to training, materials or execution of protocols for an organization or person" ;
  rdfs:subClassOf obo:OMRSE_00000048 .

obo:RO_0000052 a rdf:Property ;
  rdfs:label "characteristic of"@en ;
  rdfs:comment "a relation between a specifically dependent continuant (the characteristic) and any other entity (the bearer), in which the characteristic depends on the bearer for its existence."@en ;
  rdfs:range obo:BFO_0000040 , obo:NCBITaxon_9606 , obo:OBI_0100051 , <https://w3id.org/linkml/Any> .

obo:BFO_0000017 a rdfs:Class ;
  rdfs:label "realizable entity"@en ;
  rdfs:comment "A specifically dependent continuant  that inheres in continuant  entities and are not exhibited in full at every time in which it inheres in an entity or group of entities. The exhibition or actualization of a realizable entity is a particular manifestation, functioning or process that occurs under certain circumstances."@en ;
  rdfs:subClassOf obo:BFO_0000020 .

obo:UBERON_0001988 a rdfs:Class ;
  rdfs:label "feces" ;
  rdfs:comment "Portion of semisolid bodily waste discharged through the anus[MW,modified]." ;
  rdfs:subClassOf obo:UBERON_0000463 .

obo:FMA_22109 a rdfs:Class ;
  rdfs:label "Right tibial nerve" ;
  rdfs:subClassOf obo:UBERON_0001323 .

obo:OBIB_0000642 a rdfs:Class ;
  rdfs:label "settlement part of address biobank contact"@en ;
  rdfs:comment "The part of a biobank contact's adress denoting a settlement."@en ;
  rdfs:subClassOf obo:OBIB_0000641 .

obo:OBIB_0000333 a rdfs:Class ;
  rdfs:label "comment on preparation of FFPE tissue section" ;
  rdfs:comment "A textual entity that states information relevant to preparation of a formalin-fixed paraffin-embedded (FFPE) tissue section." ;
  rdfs:subClassOf obo:IAO_0000300 .

obo:OMRSE_00002072 a rdfs:Class ;
  rdfs:label "role in human social processes"@en ;
  rdfs:comment "A role inhering in an entity realized by social interactions in human society."@en ;
  rdfs:subClassOf obo:OMRSE_00000048 .

obo:OBI_0002126 a rdfs:Class ;
  rdfs:label "IHC-stained fixed tissue slide specimen"@en ;
  rdfs:comment "A fixed tissue slide specimen that is the output of immunohistochemistry slide staining."@en ;
  rdfs:subClassOf obo:BFO_0000002 , obo:OMIABIS_0000052 .

obo:OBI_0002660 a rdfs:Class ;
  rdfs:label "abdominal wall fat pad biopsy" ;
  rdfs:comment "A biopsy involving the collection of a small part of the abdominal wall fat pad." ;
  rdfs:subClassOf obo:OBI_0002650 .

obo:OBIB_0000027 a rdfs:Class ;
  rdfs:label "filled data confirm questionnaire"@en ;
  rdfs:comment "A data confirm questionnaire which has been filled out by a human subject recruiter." ;
  rdfs:subClassOf obo:OBIB_0000017 .

obo:OBI_0002544 a rdfs:Class ;
  rdfs:label "esophagogastric junction specimen" ;
  rdfs:comment "A specimen that is derived from the esophagogastric junction." ;
  rdfs:subClassOf obo:OBI_0001479 .

obo:UBERON_0000465 a rdfs:Class ;
  rdfs:label "material anatomical entity" ;
  rdfs:comment "Anatomical entity that has mass." ;
  rdfs:subClassOf obo:BFO_0000040 .

obo:OBIB_0000573 a rdfs:Class ;
  rdfs:label "clinical history of clotting disorders" ;
  rdfs:comment "A clinical history in which there is a history of clotting disorders, such as hemophilia, requiring treatment with human-derived clotting factors." ;
  rdfs:subClassOf obo:OGMS_0000015 .

obo:OBI_0001156 a rdfs:Class ;
  rdfs:label "age since planting measurement datum"@en ;
  rdfs:comment "An age measurement datum that is the result of the measurement of the age of an organism since planting, the process of placing a plant in media (e.g. soil) to allow it to grow, which excludes sowing." ;
  rdfs:subClassOf obo:OBI_0001167 .

obo:OBI_0002157 a rdfs:Class ;
  rdfs:label "HBV surface antigen assay" ;
  rdfs:comment "An analyte assay that is meant to detect hepatitis B virus (HBV) surface antigens." ;
  rdfs:subClassOf obo:OBI_0000443 .

obo:OBIB_0000392 a rdfs:Class ;
  rdfs:label "greatest tumor dimension on slide" ;
  rdfs:comment "A length measurement datum that is the result of measuring the maximum length of a tumor specimen as presented on a slide." ;
  rdfs:subClassOf obo:IAO_0000408 .

obo:OBI_0000371 a rdfs:Class ;
  rdfs:label "heat function"@en ;
  rdfs:comment "A heat function is a function that increases the internal kinetic energy of a material"@en ;
  rdfs:subClassOf obo:BFO_0000034 .

obo:OMIABIS_0001025 a rdfs:Class ;
  rdfs:label "obsolete survey plan specification" ;
  rdfs:subClassOf <http://www.geneontology.org/formats/oboInOwl#ObsoleteClass> .

obo:ICO_0000075 a rdfs:Class ;
  rdfs:label "obsolete authorization document" ;
  rdfs:comment "A document that is the output of an authorization process."@en ;
  rdfs:subClassOf obo:IAO_0000310 .

obo:OBI_0002394 a rdfs:Class ;
  rdfs:label "number of pregnancies" ;
  rdfs:comment "A measurement datum of the total number of pregnancies a woman has had." ;
  rdfs:subClassOf obo:IAO_0000109 .

obo:OBIB_0000188 a rdfs:Class ;
  rdfs:label "left lung mass excision" ;
  rdfs:comment "A surgical procedure to remove a mass (growth or tumor) in the left lung." ;
  rdfs:subClassOf obo:OBIB_0000716 .

obo:PATO_0001421 a rdfs:Class ;
  rdfs:label "alive" ;
  rdfs:comment "A viability quality inhering in a bearer by virtue of the bearer's condition before death." ;
  rdfs:subClassOf obo:PATO_0000169 .

obo:OBIB_0000647 a rdfs:Class ;
  rdfs:label "email address of sample collection or study contact"@en ;
  rdfs:comment "An email address for the purpose of contacting a sample collection or study contact person."@en ;
  rdfs:subClassOf obo:IAO_0000429 .

obo:IAO_0000009 a rdfs:Class ;
  rdfs:label "datum label"@en ;
  rdfs:comment "A label is a symbol that is part of some other datum and is used to either partially define  the denotation of that datum or to provide a means for identifying the datum as a member of the set of data with the same label"@en ;
  rdfs:subClassOf obo:IAO_0000030 .

obo:OBIB_0000682 a rdfs:Class ;
  rdfs:label "end date of sampling for biobank"@en ;
  rdfs:comment "A data item that indicates the time when the sampling of specimens for a biobank ended."@en ;
  rdfs:subClassOf obo:IAO_0000027 .

obo:OBIB_0000620 a rdfs:Class ;
  rdfs:label "ISO 3166-1 alpha-2 code"@en ;
  rdfs:comment "An identifier that consists of two letters, is part of the ISO 3166-1, and designates countries, dependent territories, and special areas of geographical interest."@en ;
  rdfs:subClassOf obo:IAO_0020000 .

obo:OBIB_0000247 a rdfs:Class ;
  rdfs:label "specimen was collected and stored in accordance with the specified SOP" ;
  rdfs:comment "An information content entity indicating whether the specimen was collected and stored in accordance with the specified SOP." ;
  rdfs:subClassOf obo:IAO_0000030 .

obo:OBI_0000102 a rdfs:Class ;
  rdfs:label "responsible party role"@en ;
  rdfs:comment "a study personnel role played by a party who is accountable for the execution of a study component and can make decisions about the conduct of the study"@en ;
  rdfs:subClassOf obo:OBI_0000202 .

obo:OBIB_0000584 a rdfs:Class ;
  rdfs:label "clinical history of drug abuse" ;
  rdfs:comment "A clinical history in which there is a history of drug abuse." ;
  rdfs:subClassOf obo:OGMS_0000015 .

obo:OBIB_0000231 a rdfs:Class ;
  rdfs:label "blood specimen collection" ;
  rdfs:comment "A collecting specimen from organism that results in a blood specimen." ;
  rdfs:subClassOf obo:OBI_0600005 .

obo:OBIB_0000405 a rdfs:Class ;
  rdfs:label "comment from pathology review of FFPE slide" ;
  rdfs:comment "A textual entity that states information relevant to a review by a pathologist of a formalin-fixed paraffin-embedded (FFPE) slide." ;
  rdfs:subClassOf obo:IAO_0000300 .

obo:OBIB_0000293 a rdfs:Class ;
  rdfs:label "FFPE alcohol stage duration" ;
  rdfs:comment "A time measurement datum that is the result of measuring the duration of the alcohol stage in a formalin-fixed paraffin-embedded (FFPE) process." ;
  rdfs:subClassOf obo:IAO_0000416 .

obo:OBIB_0000242 a rdfs:Class ;
  rdfs:label "humidity in lab when blood specimen was received" ;
  rdfs:comment "A measurement datum that is the output of an assay of humidity occurring in a laboratory and performed when a blood specimen is received." ;
  rdfs:subClassOf obo:IAO_0000109 .

<http://www.ebi.ac.uk/efo/EFO_0004318> a rdfs:Class ;
  rdfs:label "smoking behavior" ;
  rdfs:comment "Inhaling and exhaling the smoke of tobacco or something similar to tobacco." ;
  rdfs:subClassOf obo:GO_0008150 .

obo:OBIB_0000636 a rdfs:Class ;
  rdfs:label "post-office box number"@en ;
  rdfs:comment "An identifier denoting a post-office box."@en ;
  rdfs:subClassOf obo:IAO_0020000 .

obo:IAO_0000219 a rdf:Property ;
  rdfs:label "denotes"@en ;
  rdfs:comment "A primitive, instance-level, relation obtaining between an information content entity and some portion of reality. Denotation is what happens when someone creates an information content entity E in order to specifically refer to something. The only relation between E and the thing is that E can be used to 'pick out' the thing. This relation connects those two together. Freedictionary.com sense 3: To signify directly; refer to specifically"@en ;
  rdfs:range obo:OBIB_0000637 ;
  rdfs:subPropertyOf obo:IAO_0000136 .

obo:OBIB_0000323 a rdfs:Class ;
  rdfs:label "description of glass slide charge" ;
  rdfs:comment "A textual entity that describes the carge on a glass slide." ;
  rdfs:subClassOf obo:IAO_0000300 .

obo:OMIABIS_0000021 a rdfs:Class ;
  rdfs:label "obsolete telephone number" ;
  rdfs:subClassOf <http://www.geneontology.org/formats/oboInOwl#ObsoleteClass> .

obo:OBIB_0000454 a rdfs:Class ;
  rdfs:label "activity related to a particular specimen donor was stopped because tissue was too necrotic" ;
  rdfs:comment "An activity related to a particular specimen donor was stopped that is because the tissue was too necrotic." ;
  rdfs:subClassOf obo:OBIB_0000451 .

obo:OBIB_0000465 a rdfs:Class ;
  rdfs:label "research authorization for post mortem specimen donation not obtained because legally authorized representative felt pressured" ;
  rdfs:comment "A research authorization documentation for post mortem specimen donation because the legally authorized representative felt pressured into making a decision." ;
  rdfs:subClassOf obo:OBIB_0000459 .

obo:OBI_0002549 a rdfs:Class ;
  rdfs:label "ovary specimen" ;
  rdfs:comment "A specimen that is derived from female gonad." ;
  rdfs:subClassOf obo:OBI_0001479 .

obo:UBERON_0000948 a rdfs:Class ;
  rdfs:label "heart" ;
  rdfs:comment "A myogenic muscular circulatory organ found in the vertebrate cardiovascular system composed of chambers of cardiac muscle. It is the primary circulatory organ." ;
  rdfs:subClassOf obo:UBERON_0000465 .

obo:OBIB_0000069 a rdfs:Class ;
  rdfs:label "prosector role" ;
  rdfs:comment "A role which inheres in a person and is realized in the dissection of a body for anatomical instruction or pathological examination." ;
  rdfs:subClassOf obo:BFO_0000023 .

obo:OBIB_0000058 a rdfs:Class ;
  rdfs:label "Location below resection" ;
  rdfs:comment "An anatomical location that is just below (1 cm) the site of surgery." ;
  rdfs:subClassOf obo:FMA_50707 .

obo:OBI_0002538 a rdfs:Class ;
  rdfs:label "cerebellum specimen" ;
  rdfs:comment "A specimen that is derived from cerebellum." ;
  rdfs:subClassOf obo:OBI_0001479 .

obo:OBIB_0000370 a rdfs:Class ;
  rdfs:label "date and time FFPE tissue processor cycle ended" ;
  rdfs:comment "A data item indicating the date and time when a tissue processor cycle ended as part of a formalin-fixed paraffin-embedded (FFPE) process." ;
  rdfs:subClassOf obo:IAO_0000027 .

obo:OBIB_0000204 a rdfs:Class ;
  rdfs:label "parent specimen ID" ;
  rdfs:comment "A specimen ID denoting a specimen that is used to create a specimen family." ;
  rdfs:subClassOf obo:OBIB_0000721 .

obo:BFO_0000145 a rdfs:Class ;
  rdfs:label "relational quality"@en ;
  rdfs:comment "b is a relational quality = Def. for some independent continuants c, d and for some time t: b quality_of c at t & b quality_of d at t. (axiom label in BFO2 Reference: [057-001])"@en ;
  rdfs:subClassOf obo:BFO_0000019 .

obo:OBIB_0000185 a rdfs:Class ;
  rdfs:label "right lung biopsy" ;
  rdfs:comment "A biopsy of the right lung." ;
  rdfs:subClassOf obo:OBI_0002650 .

obo:OBIB_0000570 a rdfs:Class ;
  rdfs:label "Indication of recent cocaine use" ;
  rdfs:comment "An information content entity that indicates whether an individual recently used cocaine." ;
  rdfs:subClassOf obo:IAO_0000030 .

obo:OBIB_0000236 a rdfs:Class ;
  rdfs:label "blood specimen volume" ;
  rdfs:comment "A scalar measurement datum that is the output of a volume measurement assay that has a blood specimen as evaluant." ;
  rdfs:subClassOf obo:IAO_0000032 .

obo:IAO_8000014 a rdfs:Class ;
  rdfs:label "generated ontology module"@en ;
  rdfs:comment "An ontology module that is automatically generated, for example via a SPARQL query or via template and a CSV."@en ;
  rdfs:subClassOf obo:IAO_8000000 .

obo:UBERON_0001150 a rdfs:Class ;
  rdfs:label "body of pancreas" ;
  rdfs:comment "The body of the pancreas is a subsection of the pancreas organ in the human body. It is somewhat prismatic in shape, and has three surfaces: anterior, posterior, and inferior. It is at the same level as the transpyloric plane. [WP,unvetted]." ;
  rdfs:subClassOf obo:UBERON_0000064 .

obo:OBIB_0000048 a rdfs:Class ;
  rdfs:label "nicotine material"@en ;
  rdfs:comment "A processed material that contains nicotine." ;
  rdfs:subClassOf obo:OBI_0000047 .

obo:OBIB_0000010 a rdfs:Class ;
  rdfs:label "freezer shelf"@en ;
  rdfs:comment "A device that is part of a freezer and consists of a solid horizontal surface to keep material in the freezer on a flat surface." ;
  rdfs:subClassOf obo:OBI_0000968 .

obo:OBIB_0000530 a rdfs:Class ;
  rdfs:label "time since last usage of hormone replacement therapy" ;
  rdfs:comment "A time measurement datum that is the result of measuring the time elapsed since the participant last used hormonally replacement therapy." ;
  rdfs:subClassOf obo:IAO_0000416 .

obo:OBI_0000880 a rdfs:Class ;
  rdfs:label "RNA extract" ;
  rdfs:comment "an extract which is the output of an extraction process in which RNA molecules are isolated from a specimen." ;
  rdfs:subClassOf obo:OBI_0001010 .

obo:OBI_0000643 a rdf:Property ;
  rdfs:label "has grain" ;
  rdfs:comment "the relation of the cells in the finger of the skin to the finger, in which an indeterminate number of grains are parts of the whole by virtue of being grains in a collective that is part of the whole, and in which removing one granular part does not nec- essarily damage or diminish the whole. Ontological Whether there is a fixed, or nearly fixed number of parts - e.g. fingers of the hand, chambers of the heart, or wheels of a car - such that there can be a notion of a single one being missing, or whether, by contrast, the number of parts is indeterminate - e.g., cells in the skin of the hand, red cells in blood, or rubber molecules in the tread of the tire of the wheel of the car." ;
  rdfs:range <https://w3id.org/linkml/Any> , obo:OBI_0001866 , obo:CL_0000010 ;
  rdfs:subPropertyOf obo:BFO_0000051 .

obo:OMIABIS_0001006 a rdfs:Class ;
  rdfs:label "obsolete end date of sampling for biobank" ;
  rdfs:subClassOf <http://www.geneontology.org/formats/oboInOwl#ObsoleteClass> .

obo:OBI_0000832 a rdfs:Class ;
  rdfs:label "measurement device" ;
  rdfs:comment "A device in which a measure function inheres." ;
  rdfs:subClassOf obo:OBI_0000968 .

obo:IAO_0000416 a rdfs:Class ;
  rdfs:label "time measurement datum"@en ;
  rdfs:comment "A scalar measurement datum that is the result of measuring a temporal interval"@en ;
  rdfs:subClassOf obo:IAO_0000032 .

obo:OBI_0002516 a rdfs:Class ;
  rdfs:label "brain specimen" ;
  rdfs:comment "A specimen that is derived from brain." ;
  rdfs:subClassOf obo:OBI_0001479 .

obo:OMIABIS_0000049 a rdfs:Class ;
  rdfs:label "obsolete bone marrow specimen" ;
  rdfs:subClassOf <http://www.geneontology.org/formats/oboInOwl#ObsoleteClass> .

obo:OBI_0002607 a rdfs:Class ;
  rdfs:label "oral swab specimen" ;
  rdfs:comment "A specimen that is collected with a swab from the inside surface of a mouth." ;
  rdfs:subClassOf obo:OBI_0002599 .

obo:OBI_0001933 a rdfs:Class ;
  rdfs:label "value specification" ;
  rdfs:comment "An information content entity that specifies a value within a classification scheme or on a quantitative scale." ;
  rdfs:subClassOf obo:IAO_0000030 .

obo:CHEBI_6834 a rdfs:Class ;
  rdfs:label "methohexital sodium" ;
  rdfs:comment "The sodium salt of methohexital." ;
  rdfs:subClassOf obo:CHEBI_23367 .

obo:NCIT_C126533 a rdfs:Class ;
  rdfs:label "Southeast Asian" ;
  rdfs:comment "Denotes a person whose ancestry is in any of the Asian countries south of China, east of India, west of New Guinea and north of Australia." ;
  rdfs:subClassOf obo:OBI_0000181 .

obo:OBI_2000006 a rdfs:Class ;
  rdfs:label "upper respiratory tract specimen" ;
  rdfs:comment "A specimen that is derived from some upper respiratory tract" ;
  rdfs:subClassOf obo:OBI_0001479 .

obo:OBIB_0000660 a rdfs:Class ;
  rdfs:label "fixed tissue block specimen"@en ;
  rdfs:comment "A fixed tissue specimen that is in block form."@en ;
  rdfs:subClassOf obo:OBIB_0000659 .

obo:OBIB_0000422 a rdfs:Class ;
  rdfs:label "comment on gross evaluation of resected tissue specimen" ;
  rdfs:comment "A textual entity that states information relevant to gross evaluation of a resected tissue specimen." ;
  rdfs:subClassOf obo:IAO_0000300 .

obo:OBIB_0000016 a rdfs:Class ;
  rdfs:label "blood spot card box"@en ;
  rdfs:comment "A device that is designed to contain blood spot cards." ;
  rdfs:subClassOf obo:OBI_0000967 .

obo:OBIB_0000038 a rdf:Property ;
  rdfs:label "has actual load"@en ;
  rdfs:comment "A relation that relates a container to a measurement datum that specifies the actual amount of material in the container." ;
  rdfs:domain obo:OBI_0000967 ;
  rdfs:range obo:IAO_0000109 .

obo:OBIB_0000037 a rdf:Property ;
  rdfs:label "has maximum capacity"@en ;
  rdfs:comment "A relation that relates a container to a measurement datum that specifies the maximum capacity of the container." ;
  rdfs:domain obo:OBI_0000967 ;
  rdfs:range obo:IAO_0000109 .

obo:OBIB_0000606 a rdfs:Class ;
  rdfs:label "indication of performing sexual acts in exchange for money or drugs" ;
  rdfs:comment "An information content entity in which there is an indication of whether an individual ever performed sexual acts in exchange for money or drugs." ;
  rdfs:subClassOf obo:IAO_0000030 .

obo:OBIB_0000261 a rdfs:Class ;
  rdfs:label "presence of gross hemolysis of plasma observed" ;
  rdfs:comment "An information content entity indicating whether the presence of gross hemolysis of plasma was observed." ;
  rdfs:subClassOf obo:IAO_0000030 .

obo:OMRSE_00000206 a rdfs:Class ;
  rdfs:label "OMB ethnic identity information content entity"@en ;
  rdfs:comment "An ethnic identity information content entity that uses OMB terminology for ethnicity or terminology that is strictly mapped onto the OMB ethnicity terms."@en ;
  rdfs:subClassOf obo:OMRSE_00000205 .

obo:IAO_8000003 a rdfs:Class ;
  rdfs:label "main release ontology module"@en ;
  rdfs:comment "An ontology module that is intended to be the primary release product and the one consumed by the majority of tools."@en ;
  rdfs:subClassOf obo:IAO_8000000 .

obo:OBIB_0000133 a rdfs:Class ;
  rdfs:label "vital sign blood pressure variance late in organ excision" ;
  rdfs:comment "A data item on the duration of blood pressure variances of greater than 20 mmHg from a patient's pre-operative baseline from 15 minutes post anesthesia induction to the organ excision." ;
  rdfs:subClassOf obo:IAO_0000027 .

obo:OMIABIS_0001007 a rdfs:Class ;
  rdfs:label "obsolete start date of sampling for biobank" ;
  rdfs:subClassOf <http://www.geneontology.org/formats/oboInOwl#ObsoleteClass> .

obo:IDO_0001013 a rdfs:Class ;
  rdfs:label "immunosuppressed human experiencing chronic systemic steroid use-based immunosuppression"@en ;
  rdfs:comment "An immunosuppressed organism that is a human experiencing chronic systemic steroid use-based immunosuppression." ;
  rdfs:subClassOf obo:IDO_0000456 .

obo:PATO_0015009 a rdfs:Class ;
  rdfs:label "humidity" ;
  rdfs:comment "A quality inhering in air by virtue of the partial pressure exerted by the bearer's water vapour content." ;
  rdfs:subClassOf obo:PATO_0001018 .

obo:OBIB_0000073 a rdfs:Class ;
  rdfs:label "case report form completion SOP" ;
  rdfs:comment "A standard operating procedure for properly and completely filling out a case report form." ;
  rdfs:subClassOf obo:OBIB_0000070 .

obo:OMIABIS_0001013 a rdfs:Class ;
  rdfs:label "obsolete storage temperature setting" ;
  rdfs:subClassOf <http://www.geneontology.org/formats/oboInOwl#ObsoleteClass> .

obo:OBI_0002530 a rdfs:Class ;
  rdfs:label "adipose tissue specimen" ;
  rdfs:comment "A specimen that is derived from adipose tissue." ;
  rdfs:subClassOf obo:OBI_0001479 .

obo:OBI_0500000 a rdfs:Class ;
  rdfs:label "study design"@en ;
  rdfs:comment "A plan specification comprised of protocols (which may specify how and what kinds of data will be gathered) that are executed as part of an investigation and is realized during a study design execution." ;
  rdfs:subClassOf obo:IAO_0000104 .

obo:OBI_0001173 a rdfs:Class ;
  rdfs:label "service" ;
  rdfs:comment "A planned process in which a service provider performs a task (i.e. a planned process) for a service consumer." ;
  rdfs:subClassOf obo:OBI_0000011 .

obo:OMIABIS_0000044 a rdfs:Class ;
  rdfs:label "obsolete postal code for sample collection or study contact" ;
  rdfs:subClassOf <http://www.geneontology.org/formats/oboInOwl#ObsoleteClass> .

obo:DOID_3907 a rdfs:Class .

obo:OBIB_0000592 a rdfs:Class ;
  rdfs:label "clinical history of Hepatitis C" ;
  rdfs:comment "A clinical history in which there is a history of Hepatitis C infection." ;
  rdfs:subClassOf obo:OGMS_0000015 .

obo:OBI_0002454 a rdfs:Class ;
  rdfs:label "clinically relevant lifestyle inclusion criterion"@en ;
  rdfs:comment "An inclusion criterion that defines and states one or more clinically relevant planned processes that a human being actively participates in , which, if met, makes the human being suitable for a given task or participation in a given process."@en ;
  rdfs:subClassOf obo:OBI_0500027 .

obo:OBIB_0000718 a rdfs:Class ;
  rdfs:label "time in formalin measurement"@en ;
  rdfs:comment "A time measurement datum that states the duration during which a specimen was submerged in formalin."@en ;
  rdfs:subClassOf obo:IAO_0000416 .

obo:OBIB_0000084 a rdfs:Class ;
  rdfs:label "surgical ligature process" ;
  rdfs:comment "A planned process to stop blood flow for an organ during a surgical procedure using a clamp or ligature." ;
  rdfs:subClassOf obo:OBI_0000011 .

<http://www.ebi.ac.uk/efo/EFO_0003961> a rdfs:Class ;
  rdfs:label "hormone replacement therapy" ;
  rdfs:comment "Therapeutic use of hormones to alleviate the effects of hormone deficiency." ;
  rdfs:subClassOf obo:OGMS_0000090 .

obo:DOID_4000 a rdfs:Class .

obo:OBIB_0000493 a rdfs:Class ;
  rdfs:label "authorization not obtained for whole brain donation" ;
  rdfs:comment "An authorization documentation for post mortem specimen donation in which authorization is not obtained for whole brain donation." ;
  rdfs:subClassOf obo:OBIB_0000490 .

obo:OBI_0002077 a rdfs:Class ;
  rdfs:label "specimens derived from shared ancestor"@en ;
  rdfs:comment "A collection of specimens derived from one common specimen via one or more material processing process(es)."@en ;
  rdfs:subClassOf obo:OBI_0002076 .

obo:RO_0002351 a rdf:Property ;
  rdfs:label "has member"@en ;
  rdfs:comment "has member is a mereological relation between a collection and an item." ;
  rdfs:range obo:OBI_0100051 , obo:OBI_0000245 ;
  rdfs:subPropertyOf obo:BFO_0000051 .

obo:OBIB_0000424 a rdfs:Class ;
  rdfs:label "photograph of tissue was taken in pathology gross room" ;
  rdfs:comment "An information content entity that is an indicator of whether a photograph was taken in the pathology gross room of a resected tissue specimen." ;
  rdfs:subClassOf obo:IAO_0000030 .

obo:PATO_0001985 a rdfs:Class ;
  rdfs:label "frozen" ;
  rdfs:comment "A quality inhering in a bearer by virtue of the bearer's being kept below its freezing point." ;
  rdfs:subClassOf obo:PATO_0000146 .

obo:OBI_0002555 a rdfs:Class ;
  rdfs:label "age group inclusion criterion"@en ;
  rdfs:comment "An inclusion criterion that defines and states an age bracket which, if met, makes an entity suitable for a given task or participation in a given process." ;
  rdfs:subClassOf obo:OBI_0500027 .

obo:OBI_0002415 a rdfs:Class ;
  rdfs:label "exposure to environmental and workplace carcinogens history" ;
  rdfs:comment "An information content entity that indicates the exposure of an individual to carcinogens in the workplace or environment." ;
  rdfs:subClassOf obo:IAO_0000030 .

obo:OBIB_0000528 a rdfs:Class ;
  rdfs:label "comment on the use of hormonally based birth control" ;
  rdfs:comment "A textual entity that states additional information relevant to the use of hormonally based birth control." ;
  rdfs:subClassOf obo:IAO_0000300 .

obo:OBIB_0000476 a rdfs:Class ;
  rdfs:label "date of research authorization verification" ;
  rdfs:comment "A data item that indicates the calendar date on which the receipt of the research authorization was verified by study personnel." ;
  rdfs:subClassOf obo:IAO_0000027 .

obo:OBIB_0000356 a rdfs:Class ;
  rdfs:label "central biobank" ;
  rdfs:comment "A biobank which receives its specimens primarily/exclusively from tissue source sites.� Activities include receipt, some processing, production of slides/images of the tissue, storage, and retrieval/shipping of materials on-demand." ;
  rdfs:subClassOf obo:OBIB_0000616 .

obo:CHEBI_9561 a rdfs:Class ;
  rdfs:label "thiopental sodium" ;
  rdfs:comment "An organic sodium salt having thiopental(1-) as the counter-ion." ;
  rdfs:subClassOf obo:CHEBI_23367 .

obo:OBIB_0000283 a rdfs:Class ;
  rdfs:label "date of specimen receipt for pathologist processing" ;
  rdfs:comment "A data item indicating the calendar date when a specimen arrives in the gross pathology room for processing and review." ;
  rdfs:subClassOf obo:IAO_0000027 .

obo:OBIB_0000316 a rdfs:Class ;
  rdfs:label "comment on FFPE tissue block storage" ;
  rdfs:comment "A textual entity that states information relevant to storage of a formalin-fixed paraffin-embedded (FFPE) tissue block." ;
  rdfs:subClassOf obo:IAO_0000300 .

obo:FMA_37829 a rdfs:Class ;
  rdfs:label "Skin of right leg" ;
  rdfs:subClassOf obo:UBERON_0002097 .

obo:OBI_0002146 a rdfs:Class ;
  rdfs:label "HIV antibody assay" ;
  rdfs:comment "An antigen specific antibodies assay that is meant to detect antibodies that bind to human immunodeficiency virus (HIV) antigens." ;
  rdfs:subClassOf obo:OBI_0002145 .

obo:OBI_0002425 a rdfs:Class ;
  rdfs:label "radiation treatment exclusion criteria" ;
  rdfs:comment "An exclusion criterion that defines whether radiation was received or is being received for a previous  or current cancer, which when met, makes an individual unsuitable for a given task or participation in a given process" ;
  rdfs:subClassOf obo:OBI_0500028 .

obo:OBIB_0000051 a rdfs:Class ;
  rdfs:label "smoking start date"@en ;
  rdfs:comment "A time measurement datum which is the start date of a smoking behavior." ;
  rdfs:subClassOf obo:IAO_0000416 .

obo:OBIB_0000435 a rdfs:Class ;
  rdfs:label "normal adjacent tissue released to the biobank in addition to tumor tissue" ;
  rdfs:comment "An information content entity that is an indicator of whether normal adjacent tissue was released to the biobank in addition to the tumor tissue." ;
  rdfs:subClassOf obo:IAO_0000030 .

obo:PATO_0000169 a rdfs:Class ;
  rdfs:label "viability" ;
  rdfs:comment "An organismal quality inhering in a bearer or a population by virtue of the bearer's disposition to survive and develop normally or the number of surviving individuals in a given population." ;
  rdfs:subClassOf obo:PATO_0001995 .

obo:OBI_0002088 a rdfs:Class ;
  rdfs:label "specimen container" ;
  rdfs:comment "A container with the function of containing a specimen." ;
  rdfs:subClassOf obo:OBI_0000967 .

obo:OBI_0002656 a rdfs:Class ;
  rdfs:label "core needle biopsy" ;
  rdfs:comment "A biopsy that uses a hollow tube to collect a core of tissue." ;
  rdfs:subClassOf obo:OBI_0002654 .

obo:OBIB_0000200 a rdfs:Class ;
  rdfs:label "receipt and dissection of surgical specimen SOP" ;
  rdfs:comment "A standard operating procedure for the receipt and dissection of surgical tissue in a biobank." ;
  rdfs:subClassOf obo:OBIB_0000070 .

obo:OBIB_0000272 a rdfs:Class ;
  rdfs:label "specimen transporting organization" ;
  rdfs:comment "A role borne by an organization that is the provider of a specimen that is transported to another organization." ;
  rdfs:subClassOf obo:BFO_0000023 .

obo:UBERON_0001037 a rdfs:Class ;
  rdfs:label "strand of hair" ;
  rdfs:comment "A filament, mostly protein, that grows from follicles found in the dermis[WP]." ;
  rdfs:subClassOf obo:UBERON_0000465 .

obo:OBIB_0000541 a rdfs:Class ;
  rdfs:label "progestin alone hormone replacement therapy" ;
  rdfs:comment "A hormone replacement therapy where the hormone is progestin." ;
  rdfs:subClassOf <http://www.ebi.ac.uk/efo/EFO_0003961> .

obo:OBIB_0000129 a rdfs:Class ;
  rdfs:label "time of first clamp for specimen removal" ;
  rdfs:comment "A data item that reports the time of day when the first clamp was applied to the vasculature of an organ for specimen collection." ;
  rdfs:subClassOf obo:IAO_0000027 .

obo:BFO_0000030 a rdfs:Class ;
  rdfs:label "object"@en ;
  rdfs:subClassOf obo:BFO_0000040 .

obo:NCIT_C126529 a rdfs:Class ;
  rdfs:label "North African" ;
  rdfs:comment "Denotes a person whose ancestry is in any of the countries of the northern part of the African continent: Algeria, Egypt, Libya, Morocco, Sudan, Tunisia, and Western Sahara." ;
  rdfs:subClassOf obo:OBI_0000181 .

obo:OBIB_0000581 a rdfs:Class ;
  rdfs:label "clinical history of an unexplained cough or shortness of breath" ;
  rdfs:comment "A clinical history in which there is are active signs of unexplained persistent cough and/or shortness of breath." ;
  rdfs:subClassOf obo:OGMS_0000015 .

obo:OBIB_0000517 a rdfs:Class ;
  rdfs:label "preoperative performance status score" ;
  rdfs:comment "A timing of scoring performance status that occurs prior to an operation to treat cancer." ;
  rdfs:subClassOf obo:OBIB_0000516 .

obo:OMIABIS_0000055 a rdfs:Class ;
  rdfs:label "obsolete frozen tissue block specimen" ;
  rdfs:subClassOf <http://www.geneontology.org/formats/oboInOwl#ObsoleteClass> .

obo:OBIB_0000523 a rdfs:Class ;
  rdfs:label "intrauterine device-based hormonal birth control method" ;
  rdfs:comment "A birth control method that involves the use of an intrauterine device (IUD) to deliver hormones." ;
  rdfs:subClassOf obo:NCIT_C106501 .

obo:UBERON_0001155 a rdfs:Class ;
  rdfs:label "colon" ;
  rdfs:comment "A portion of the large intestine before it becomes the rectum. In mammals, the colon is the most part of the large intestine, excluding the vermiform appendix, the rectum and the anal canal." ;
  rdfs:subClassOf obo:UBERON_0000465 .

obo:OBIB_0000696 a rdfs:Class ;
  rdfs:label "cohort study design"@en ;
  rdfs:comment "A longitudinal study that aims to study a case-defined population who presently have a certain condition or recepient of a particular treatment that are followed over time and are compared with a similar group who do not have condition."@en ;
  rdfs:subClassOf obo:OBIB_0000695 .

obo:OBIB_0000556 a rdfs:Class ;
  rdfs:label "a clinical history of contact with someone with smallpox" ;
  rdfs:comment "A clinical history in which there is a history of contact with someone who recently had smallpox." ;
  rdfs:subClassOf obo:OGMS_0000015 .

obo:OBIB_0000214 a rdfs:Class ;
  rdfs:label "buffer formula for specimen fixative" ;
  rdfs:comment "A protocol specifying the buffer formula of the fixative in which tissue specimens are processed." ;
  rdfs:subClassOf obo:OBI_0000272 .

obo:OBIB_0002007 a rdfs:Class ;
  rdfs:label "specimen gross appearance of tumor edge"@en ;
  rdfs:comment "A specimen gross appearance of the border of the tumor with non-tumorous tissue." ;
  rdfs:subClassOf obo:OBIB_0000209 .

obo:FMA_63008 a rdfs:Class ;
  rdfs:label "Mucosa of abdominal part of esophagus" ;
  rdfs:subClassOf obo:UBERON_0002469 .

obo:IAO_0000422 a rdfs:Class ;
  rdfs:label "postal address"@en ;
  rdfs:comment "A textual entity that is used as directive to deliver something to a person, or organization" ;
  rdfs:subClassOf obo:IAO_0000300 .

obo:OBIB_0000032 a rdfs:Class ;
  rdfs:label "vacutainer"@en ;
  rdfs:comment "A test tube  which is either a sterile glass or plastic tube with a closure that is evacuated to create a vacuum inside the tube facilitating the draw of a predetermined volume of liquid. Most commonly used to draw a blood sample directly from the vein, these also are used to collect urine samples. Vacutainer tube may contain additives designed to stabilize and preserve the specimen prior to analytical testing." ;
  rdfs:subClassOf obo:OBI_0000967 .

obo:OBIB_0000552 a rdfs:Class ;
  rdfs:label "clinical history of blood transfusion in foreign country" ;
  rdfs:comment "A clinical history in which there is a history of receiving a blood transfusion while in another country." ;
  rdfs:subClassOf obo:OGMS_0000015 .

obo:OBIB_0000396 a rdfs:Class ;
  rdfs:label "histologic profile quantitative assessment of tumor slide specimen surface area" ;
  rdfs:comment "A data item that is made up of percentages of different histology-based assessments of a tumor slide specimen that in aggregate describe the total tumor surface area (i.e. add up to 100%)." ;
  rdfs:subClassOf obo:IAO_0000027 .

obo:NCBITaxon_314146 a rdfs:Class ;
  rdfs:label "Euarchontoglires" ;
  rdfs:subClassOf obo:NCBITaxon_40674 .

obo:OBIB_0000118 a rdfs:Class ;
  rdfs:label "abdominoperineal resection" ;
  rdfs:comment "A surgical procedure in which the anus, rectum, and sigmoid colon are removed." ;
  rdfs:subClassOf obo:OBIB_0000716 .

obo:OBIB_0000444 a rdfs:Class ;
  rdfs:label "top priority tumor specimen was obtained and processed with a particular FFPE fixation delay protocol" ;
  rdfs:comment "An information content entity that is an indicator of whether a tumor specimen was obtained and processed with a particular FFPE fixation delay protocol to meet the top priority for tissue procurement." ;
  rdfs:subClassOf obo:IAO_0000030 .

obo:OBI_0002426 a rdfs:Class ;
  rdfs:label "chemotherapy treatment within the recent past exclusion criterion" ;
  rdfs:comment "An exclusion criterion that defines whether chemotherapy was received within a certain timeframe, which when met, makes an individual unsuitable for a given task or participation in a given process." ;
  rdfs:subClassOf obo:OBI_0500028 .

obo:OBIB_0000281 a rdfs:Class ;
  rdfs:label "specimen shipment received in poor condition" ;
  rdfs:comment "An information content entity indicating that the physical condition of a specimen upon receipt after transport was poor." ;
  rdfs:subClassOf obo:IAO_0000030 .

obo:OBIB_0000220 a rdfs:Class ;
  rdfs:label "buffered formalin condition" ;
  rdfs:comment "A quality that inheres in buffered formalin by virtue of its usage and processing." ;
  rdfs:subClassOf obo:BFO_0000019 .

obo:UBERON_0000173 a rdfs:Class ;
  rdfs:label "amniotic fluid" ;
  rdfs:comment "Amniotic fluid is a bodily fluid consisting of watery liquid surrounding and cushioning a growing fetus within the amnion. It allows the fetus to move freely without the walls of the uterus being too tight against its body. Buoyancy is also provided. The composition of the fluid changes over the course of gestation. Initially, amniotic fluid is similar to maternal plasma, mainly water with electrolytes. As the fetus develops, proteins, carbohydrates, lipids, phospholipids originating from the lungs, fetal cells, and urea are deposited in the fluid." ;
  rdfs:subClassOf obo:UBERON_0000463 .

obo:OBI_0302887 a rdfs:Class ;
  rdfs:label "staining"@en ;
  rdfs:comment "Staining is a process which results in the addition a class-specific (DNA, proteins, lipids, carbohydrates) dye to a substrate to qualify or quantify the presence of a specific compound."@en ;
  rdfs:subClassOf obo:OBI_0000094 .

obo:OBIB_0000675 a rdfs:Class ;
  rdfs:label "normal state specimen datum"@en ;
  rdfs:comment "A specimen disease state datum that specifies that the specimenin questions consists of normal tissue."@en ;
  rdfs:subClassOf obo:OBIB_0000672 .

obo:OBIB_0000509 a rdfs:Class ;
  rdfs:label "moderate alcohol consumption history" ;
  rdfs:comment "An Alcohol Use History in which alcohol consumption was equal to or less than 2 drinks per day for men and 1 drink or less per day for women." ;
  rdfs:subClassOf obo:NCIT_C81229 .

obo:PATO_0000117 a rdfs:Class ;
  rdfs:label "size" ;
  rdfs:comment "A morphology quality inhering in a bearer by virtue of the bearer's physical magnitude." ;
  rdfs:subClassOf obo:PATO_0000051 .

obo:BFO_0000006 a rdfs:Class ;
  rdfs:label "spatial region"@en ;
  rdfs:subClassOf obo:BFO_0000141 .

obo:OBI_0000981 a rdfs:Class ;
  rdfs:label "agar stab specimen" ;
  rdfs:comment "a specimen that is output of a process that cell culture inoculated into agar for long term storage." ;
  rdfs:subClassOf obo:OBI_0001472 .

obo:PATO_0000128 a rdfs:Class ;
  rdfs:label "weight" ;
  rdfs:comment "A physical quality inhering in a bearer that has mass near a gravitational body. Important usage note: Note that this ontology has a class for a similar concept, mass (PATO:0000125). Mass and weight are not equivalent. For most use cases, the class mass is strongly preferred over weight." ;
  rdfs:subClassOf obo:PATO_0001018 .

obo:BFO_0000182 a rdfs:Class ;
  rdfs:label "history"@en ;
  rdfs:subClassOf obo:BFO_0000015 .

obo:OBI_0000047 a rdfs:Class ;
  rdfs:label "processed material"@en ;
  rdfs:comment "Is a material entity that is created or changed during material processing."@en ;
  rdfs:subClassOf obo:BFO_0000040 .

obo:OBI_0001528 a rdfs:Class ;
  rdfs:label "material service" ;
  rdfs:comment "A service which has a material entity as specified input and/or specified output." ;
  rdfs:subClassOf obo:OBI_0001173 .

obo:DOID_2394 a rdfs:Class .

obo:CL_0000558 a rdfs:Class ;
  rdfs:label "reticulocyte" ;
  rdfs:comment "An immature erythrocyte that changes the protein composition of its plasma membrane by exosome formation and extrusion. The types of protein removed differ between species though removal of the transferrin receptor is apparent in mammals and birds." ;
  rdfs:subClassOf obo:CL_0000000 .

obo:OBIB_0000595 a rdfs:Class ;
  rdfs:label "clinical history of sarcoidosis" ;
  rdfs:comment "A clinical history in which there is a history of sarcoidosis." ;
  rdfs:subClassOf obo:OGMS_0000015 .

obo:UBERON_0001496 a rdfs:Class ;
  rdfs:label "ascending aorta" ;
  rdfs:comment "The ascending aorta is the portion of the aorta in a two-pass circulatory system that lies between the heart and the arch of aorta[GO]. A portion of the aorta commencing at the upper part of the base of the left ventricle, on a level with the lower border of the third costal cartilage behind the left half of the sternum; it passes obliquely upward, forward, and to the right, in the direction of the heart's axis, as high as the upper border of the second right costal cartilage, describing a slight curve in its course, and being situated, about 6 cm behind the posterior surface of the sternum. The total length is about 5 cm in length [Wikipedia]." ;
  rdfs:subClassOf obo:UBERON_0000064 .

obo:OBIB_0000257 a rdfs:Class ;
  rdfs:label "name of person processing blood plasma specimen aliquots" ;
  rdfs:comment "A personal name that designates the person who processed a blood specimen to generate aliquots of blood plasma specimens." ;
  rdfs:subClassOf obo:IAO_0020015 .

obo:OBI_0002505 a rdfs:Class ;
  rdfs:label "milk specimen" ;
  rdfs:comment "A specimen that is derived from milk." ;
  rdfs:subClassOf obo:OBI_2000009 .

obo:UBERON_0002046 a rdfs:Class ;
  rdfs:label "thyroid gland" ;
  rdfs:comment "A two-lobed endocrine gland found in all vertebrates, located in front of and on either side of the trachea in humans, and producing various hormones, such as triiodothyronine and calcitonin[BTO]." ;
  rdfs:subClassOf obo:UBERON_0000465 .

obo:OBI_0001167 a rdfs:Class ;
  rdfs:label "age measurement datum"@en ;
  rdfs:comment "A time measurement datum that is the result of measurement of age of an organism" ;
  rdfs:subClassOf obo:IAO_0000416 .

obo:OMIABIS_0001002 a rdfs:Class ;
  rdfs:label "obsolete patient registry data" ;
  rdfs:subClassOf <http://www.geneontology.org/formats/oboInOwl#ObsoleteClass> .

obo:OBI_0002368 a rdfs:Class ;
  rdfs:label "clinical history of cancer" ;
  rdfs:comment "A clinical history in which there is a diagnosis of cancer." ;
  rdfs:subClassOf obo:OGMS_0000015 .

obo:UBERON_0000178 a rdfs:Class ;
  rdfs:label "blood" ;
  rdfs:comment "A fluid that is composed of blood plasma and erythrocytes." ;
  rdfs:subClassOf obo:UBERON_0006314 .

obo:OBI_0000457 a rdfs:Class ;
  rdfs:label "manufacturing"@en ;
  rdfs:comment "Manufacturing is a process with the intent to produce a processed material which will have a function for future use. A person or organization (having manufacturer role) is a participant in this process"@en ;
  rdfs:subClassOf obo:OBI_0000094 .

obo:OBI_0002533 a rdfs:Class ;
  rdfs:label "colon specimen" ;
  rdfs:comment "A specimen that is derived from colon." ;
  rdfs:subClassOf obo:OBI_0001479 .

obo:CLO_0009828 a rdfs:Class ;
  rdfs:label "immortal cell line"@en ;
  rdfs:comment "A cell line that is expected to be capable of indefinite propagation in an vitro culture." ;
  rdfs:subClassOf obo:CLO_0000031 .

obo:UBERON_0001729 a rdfs:Class ;
  rdfs:label "oropharynx" ;
  rdfs:comment "The portion of the pharynx that lies between the soft palate and the upper edge of the epiglottis." ;
  rdfs:subClassOf obo:UBERON_0000465 .

obo:OBI_0666667 a rdfs:Class ;
  rdfs:label "nucleic acid extraction"@en ;
  rdfs:comment "a material separation to recover the nucleic acid fraction of an input material"@en ;
  rdfs:subClassOf obo:OBI_0302884 .

obo:OBIB_0000225 a rdfs:Class ;
  rdfs:label "phlebotomist role" ;
  rdfs:comment "A health care provider role borne by a person trained to draw blood from a patient for clinical or medical testing, transfusions, donations, or research. Phlebotomists collect blood primarily by performing venipunctures." ;
  rdfs:subClassOf obo:OMRSE_00000012 .

obo:UBERON_0003714 a rdfs:Class ;
  rdfs:label "neural tissue" ;
  rdfs:comment "Portion of tissue in the nervous system which consists of neurons and glial cells, and may also contain parts of the vasculature." ;
  rdfs:subClassOf obo:UBERON_0000465 .

obo:IAO_8000000 a rdfs:Class ;
  rdfs:label "ontology module"@en ;
  rdfs:subClassOf obo:IAO_0000102 .

obo:OBIB_0000093 a rdfs:Class ;
  rdfs:label "time donor body refrigerated measurement" ;
  rdfs:comment "A time measurement datum that states the duration during which the specimen donor's body was refrigerated." ;
  rdfs:subClassOf obo:IAO_0000416 .

obo:OBIB_0000433 a rdfs:Class ;
  rdfs:label "dimensions of each specimen meet the criteria specified within the relevant tissue procurement SOP" ;
  rdfs:comment "An information content entity that is an indicator of whether the dimensions of each specimen meet the criteria specified within the relevant tissue procurement standard operating procedure (SOP)." ;
  rdfs:subClassOf obo:IAO_0000030 .

obo:OBIB_0000107 a rdfs:Class ;
  rdfs:label "administration of regional anaesthetic" ;
  rdfs:comment "A planned process to administer anaesthetic to a restricted area or part of the body in order to produce a loss of feeling." ;
  rdfs:subClassOf obo:OBI_0000011 .

obo:FMA_242207 a rdfs:Class ;
  rdfs:label "Cortex of right frontal lobe" ;
  rdfs:subClassOf obo:UBERON_0000064 .

obo:UBERON_0001359 a rdfs:Class ;
  rdfs:label "cerebrospinal fluid" ;
  rdfs:comment "A clear, colorless, bodily fluid, that occupies the subarachnoid space and the ventricular system around and inside the brain and spinal cord." ;
  rdfs:subClassOf obo:UBERON_0006314 .

obo:OBIB_0000199 a rdfs:Class ;
  rdfs:label "blood was hemolyzed or not useable" ;
  rdfs:comment "A reason for not banking pre-operative blood specimen which is the blood was hemolyzed or not useable." ;
  rdfs:subClassOf obo:OBIB_0000195 .

obo:OBIB_0000270 a rdfs:Class ;
  rdfs:label "date of specimen transport" ;
  rdfs:comment "A data item indicating the calendar date when a specimen was transported to another institution." ;
  rdfs:subClassOf obo:IAO_0000027 .

obo:OBIB_0000446 a rdfs:Class ;
  rdfs:label "local pathology review of QC FFPE tumor tissue H&E slide was completed" ;
  rdfs:comment "An information content entity that is an indicator of whether the local pathology review of a hematoxylin (H&E) slide derived from a quality control (QC) formalin-fixed paraffin-embedded (FFPE) tumor tissue was completed." ;
  rdfs:subClassOf obo:IAO_0000030 .

obo:OBIB_0000686 a rdfs:Class ;
  rdfs:label "count of current sampled human study participant"@en ;
  rdfs:comment "A count that is about the aggregate of individuals who have contributed biological specimens in a study."@en ;
  rdfs:subClassOf obo:APOLLO_SV_00000032 .

obo:PATO_0001018 a rdfs:Class ;
  rdfs:label "physical quality" ;
  rdfs:comment "A quality of a physical entity that exists through action of continuants at the physical level of organisation in relation to other entities." ;
  rdfs:subClassOf obo:PATO_0001241 .

obo:CHEBI_53258 a rdfs:Class ;
  rdfs:label "sodium citrate" ;
  rdfs:comment "The trisodium salt of citric acid." ;
  rdfs:subClassOf obo:CHEBI_23367 .

obo:OBI_0002388 a rdfs:Class ;
  rdfs:label "diagnosis of HIV" ;
  rdfs:comment "A diagnosis of infectious disease caused by the human immunodeficiency virus (1 or 2)." ;
  rdfs:subClassOf obo:OBI_0002385 .

obo:OBIB_0000567 a rdfs:Class ;
  rdfs:label "clinical history of exposure to toxins" ;
  rdfs:comment "A clinical history in which there is a history of exposure to toxic substances that may have led to chronic conditions." ;
  rdfs:subClassOf obo:OGMS_0000015 .

obo:OBIB_0000506 a rdfs:Class ;
  rdfs:label "date of hormonal therapy prior to surgery" ;
  rdfs:comment "A data item that reports the calendar date when hormonal therapy was received prior to surgery." ;
  rdfs:subClassOf obo:IAO_0000027 .

obo:CL_0000003 a rdfs:Class ;
  rdfs:label "native cell" ;
  rdfs:comment "A cell that is found in a natural setting, which includes multicellular organism cells 'in vivo' (i.e. part of an organism), and unicellular organisms 'in environment' (i.e. part of a natural environment)." ;
  rdfs:subClassOf obo:CL_0000000 .

obo:OBIB_0000331 a rdfs:Class ;
  rdfs:label "daily water bath maintenance" ;
  rdfs:comment "A water bath maintenance frequency that indicates that microtome maintenance is performed and recorded daily." ;
  rdfs:subClassOf obo:OBIB_0000330 .

obo:OBI_0000835 a rdfs:Class ;
  rdfs:label "manufacturer" ;
  rdfs:comment "A person or organization that has a manufacturer role" ;
  rdfs:subClassOf obo:BFO_0000040 .

obo:OBI_0400106 a rdfs:Class ;
  rdfs:label "centrifuge" ;
  rdfs:comment "A device with a rapidly rotating container that applies centrifugal force to its contents" ;
  rdfs:subClassOf obo:OBI_0000832 , obo:OBI_0000932 .

obo:OMIABIS_0000033 a rdfs:Class ;
  rdfs:label "obsolete hosted study collection" ;
  rdfs:subClassOf <http://www.geneontology.org/formats/oboInOwl#ObsoleteClass> .

obo:OBIB_0000367 a rdfs:Class ;
  rdfs:label "date and time FFPE tissue cassette placed in fixative" ;
  rdfs:comment "A data item indicating the date and time when a tissue cassette was placed in fixative as part of a formalin-fixed paraffin-embedded (FFPE) process." ;
  rdfs:subClassOf obo:IAO_0000027 .

obo:OBIB_0000268 a rdfs:Class ;
  rdfs:label "time of specimen placement on dry ice for transport" ;
  rdfs:comment "A data item indicating the time when a specimen was placed on dry ice for transport." ;
  rdfs:subClassOf obo:IAO_0000027 .

obo:OGMS_0000073 a rdfs:Class ;
  rdfs:label "diagnosis" ;
  rdfs:comment "The representation of a conclusion of a diagnostic process."@en ;
  rdfs:subClassOf obo:IAO_0000027 .

obo:IAO_8000018 a rdfs:Class ;
  rdfs:label "obo basic subset ontology module"@en ;
  rdfs:comment """A subset ontology that is designed for basic applications to continue to make certain simplifying assumptions; many of these simplifying assumptions were based on the initial version of the Gene Ontology, and have become enshrined in many popular and useful tools such as term enrichment tools.

Examples of such assumptions include: traversing the ontology graph ignoring relationship types using a naive algorithm will not lead to cycles (i.e. the ontology is a DAG); every referenced term is declared in the ontology (i.e. there are no dangling clauses).

An ontology is OBO Basic if and only if it has the following characteristics:
DAG
Unidirectional
No Dangling Clauses
Fully Asserted
Fully Labeled
No equivalence axioms
Singly labeled edges
No qualifier lists
No disjointness axioms
No owl-axioms header
No imports"""@en ;
  rdfs:seeAlso <http://owlcollab.github.io/oboformat/doc/obo-syntax.html#6.2> ;
  rdfs:subClassOf obo:IAO_8000017 .

obo:OBIB_0002013 a rdfs:Class ;
  rdfs:label "tissue specimen suitability for molecular analysis"@en ;
  rdfs:comment "A conclusion textual entity that signifies whether a specimen is acceptable for molecular analysis based on the assessment by a pathologist of a tissue specimen based on qualities such as purity and size." ;
  rdfs:subClassOf obo:IAO_0000144 .

obo:OBIB_0000413 a rdfs:Class ;
  rdfs:label "name of person in gross room receiving OR specimen" ;
  rdfs:comment "A personal name that designates the person who received a specimen in a pathology gross room from an associated operating room (OR)." ;
  rdfs:subClassOf obo:IAO_0020015 .

obo:OBIB_0000014 a rdfs:Class ;
  rdfs:label "trash container"@en ;
  rdfs:comment "A container that is used for discarded material." ;
  rdfs:subClassOf obo:OBI_0000967 .

obo:OBIB_0000250 a rdfs:Class ;
  rdfs:label "conical centrifuge tube identifier" ;
  rdfs:comment "An identifier that specifically identifies a particular conical centrifuge tube." ;
  rdfs:subClassOf obo:IAO_0020000 .

obo:OBIB_0000729 a rdfs:Class ;
  rdfs:label "sample handling"@en ;
  rdfs:comment "A planned process of preparing and submitting specimens to storage."@en ;
  rdfs:subClassOf obo:OBI_0000011 .

obo:IAO_0000132 a rdfs:Class ;
  rdfs:label "lot number"@en ;
  rdfs:comment "A lot number is an information content entity which is an identical sequence of character borne by part of manufactured product or its packaging for each instances of a product class in a discrete batch of an item. Lot numbers are usually assigned to each separate production run of an item. Manufacturing as a lot might be due to a variety of reasons, for example,  a single process during which many individuals are made from the same portion of source material. Lot numbers can be encoded in a pattern  of other information objects, such as bar codes, numerals, or patterns of dots."@en ;
  rdfs:subClassOf obo:IAO_0000028 .

obo:OBIB_0000196 a rdfs:Class ;
  rdfs:label "blood not received in biobank" ;
  rdfs:comment "A reason for not banking pre-operative blood specimen which is the blood specimen was not received in the biobank." ;
  rdfs:subClassOf obo:OBIB_0000195 .

obo:OBI_0002377 a rdfs:Class ;
  rdfs:label "mother clinical history of cancer" ;
  rdfs:comment "A clinical history in which there is a diagnosis of cancer in a female parent." ;
  rdfs:subClassOf obo:OBI_0002372 .

obo:DOID_6067 a rdfs:Class .

obo:OBIB_0000327 a rdfs:Class ;
  rdfs:label "microtome maintenance frequency" ;
  rdfs:comment "An information content entity that indicates the frequency with which microtome maintenance is performed and recorded." ;
  rdfs:subClassOf obo:IAO_0000030 .

obo:OBIB_0000342 a rdfs:Class ;
  rdfs:label "manual FFPE tissue section H&E staining" ;
  rdfs:comment "A planned process involving the manual performance of the FFPE tissue section H&E staining protocol." ;
  rdfs:subClassOf obo:OBI_0000011 .

obo:OBI_0002562 a rdfs:Class ;
  rdfs:label "country of residence inclusion criteria"@en ;
  rdfs:comment "An inclusion criterion that defines and states one or more countries of residence which, if met, makes a human being suitable for a given task or participation in a given process."@en ;
  rdfs:subClassOf obo:OBI_0500027 .

obo:CHEBI_42191 a rdfs:Class ;
  rdfs:label "EDTA(4-)" ;
  rdfs:comment "A tetracarboxylic acid anion formed by deprotonation of all four carboxy groups in ethylenediaminetetraacetic acid (EDTA)." ;
  rdfs:subClassOf obo:CHEBI_23367 .

obo:OBI_0002613 a rdfs:Class ;
  rdfs:label "environmental swab specimen" ;
  rdfs:comment "A specimen that is collected with a swab from the surface of an environmenal material." ;
  rdfs:subClassOf obo:OBI_0002599 .

<http://www.ebi.ac.uk/efo/EFO_0004774> a rdfs:Class ;
  rdfs:label "chewing tobacco behavior" ;
  rdfs:comment "Mastication of tobacco, correlated with an increased risk of oral cancers." ;
  rdfs:subClassOf obo:GO_0008150 .

obo:OBI_0002158 a rdfs:Class ;
  rdfs:label "HIV-1 nucleic acid testing" ;
  rdfs:comment "An analyte assay that is meant to detect human immunodeficiency virus (HIV-1) nucleic acids." ;
  rdfs:subClassOf obo:OBI_0000443 .

obo:OBIB_0000628 a rdfs:Class ;
  rdfs:label "email address of biobank contact person"@en ;
  rdfs:comment "An email address for the purpose of contacting a biobank contact person."@en ;
  rdfs:subClassOf obo:IAO_0000429 .

obo:OBIB_0000360 a rdfs:Class ;
  rdfs:label "collection packet component ID" ;
  rdfs:comment "An identifier that specifically identifies a particular component of a collection packet." ;
  rdfs:subClassOf obo:IAO_0020000 .

obo:OBIB_0000585 a rdfs:Class ;
  rdfs:label "clinical history of Severe Acute Respiratory Syndrome" ;
  rdfs:comment "A clinical history in which there is a history of a Severe Acute Respiratory Syndrome (SARS) diagnosis." ;
  rdfs:subClassOf obo:OGMS_0000015 .

obo:OBI_0000387 a rdfs:Class ;
  rdfs:label "cool function"@en ;
  rdfs:comment "A cool function is a function to decrease the internal kinetic energy of a material below the initial kinetic energy of that type of material."@en ;
  rdfs:subClassOf obo:BFO_0000034 .

obo:OMRSE_00000214 a rdfs:Class ;
  rdfs:label "OMB racial identity information content entity"@en ;
  rdfs:comment "A racial identity information content entity that uses OMB terminology and definitions for race or terminology that is strictly mapped onto the OMB race terms."@en ;
  rdfs:subClassOf obo:OMRSE_00000213 .

obo:OBIB_0000040 a rdfs:Class ;
  rdfs:label "collection packet with empty container and unfilled information material"@en ;
  rdfs:comment "A collection packet which contains a container without a specimen and an unfilled form that will be used to fill in information about specimen to be collected." ;
  rdfs:subClassOf obo:OBIB_0000028 .

obo:OBIB_0000408 a rdfs:Class ;
  rdfs:label "name of reviewing pathologist at organization conducting specimen collection" ;
  rdfs:comment "A personal name that designates the person who served as the pathologist reviewing a specimen slide at an organization conducting specimen collection from organisms." ;
  rdfs:subClassOf obo:IAO_0020015 .

obo:OBIB_0000244 a rdfs:Class ;
  rdfs:label "time of specimen freezing at approximately -20 degrees C" ;
  rdfs:comment "A time of specimen freezing which occurred at approximately -20�_C." ;
  rdfs:subClassOf obo:OBIB_0000724 .

obo:OBI_0302884 a rdfs:Class ;
  rdfs:label "extraction"@en ;
  rdfs:comment "A material separation in which a desired component of an input material is separated from the remainder" ;
  rdfs:subClassOf obo:OBI_0600014 .

obo:BFO_0000029 a rdfs:Class ;
  rdfs:label "site"@en ;
  rdfs:subClassOf obo:BFO_0000141 .

obo:UBERON_0000059 a rdfs:Class ;
  rdfs:label "large intestine" ;
  rdfs:comment "A subdivision of the digestive tract that connects the small intestine to the cloaca or anus. Lacks or has few villi[Kardong]." ;
  rdfs:subClassOf obo:UBERON_0000064 .

obo:IAO_0000001 a rdfs:Class ;
  rdfs:label "conditional specification"@en ;
  rdfs:comment "A directive information entity that specifies what should happen if the trigger condition is fulfilled."@en ;
  rdfs:subClassOf obo:IAO_0000033 .

obo:OMIABIS_0001020 a rdfs:Class ;
  rdfs:label "obsolete cohort study design" ;
  rdfs:subClassOf <http://www.geneontology.org/formats/oboInOwl#ObsoleteClass> .

obo:OBIB_0000472 a rdfs:Class ;
  rdfs:label "date of research protocol approval as determined by an institutional review board" ;
  rdfs:comment "A data item that indicates the calendar date on which a research protocol was approved by an Institutional Review Board related to where the research will take place." ;
  rdfs:subClassOf obo:IAO_0000027 .

obo:OBI_0000398 a rdfs:Class ;
  rdfs:label "image creation device" ;
  rdfs:comment "An image creation device is a device which captures a digitized image of an object" ;
  rdfs:subClassOf obo:OBI_0000832 , obo:OBI_0000968 .

obo:OBIB_0000432 a rdfs:Class ;
  rdfs:label "second piece of tumor tissue was collected" ;
  rdfs:comment "An information content entity that is an indicator of whether a second piece of tumor was collected and released to a biobank." ;
  rdfs:subClassOf obo:IAO_0000030 .

obo:OBIB_0000524 a rdfs:Class ;
  rdfs:label "patch-based hormonal birth control method" ;
  rdfs:comment "A birth control method that involves the administration of hormones through a transdermal patch delivery system." ;
  rdfs:subClassOf obo:NCIT_C106501 .

obo:OBIB_0000497 a rdfs:Class ;
  rdfs:label "authorization to collect of minimum number of organ/tissue types for a specific study inclusion criterion" ;
  rdfs:comment "An inclusion criterion that defines whether the specimen donor has provided authorization to allow for the minimum number of organs/tissue types for a specific study to be collected, which when met, makes a  specimen donor suitable for a given task or participation in a given process." ;
  rdfs:subClassOf obo:OBI_0500027 .

obo:OMIABIS_0001076 a rdfs:Class ;
  rdfs:label "obsolete faeces specimen" ;
  rdfs:subClassOf <http://www.geneontology.org/formats/oboInOwl#ObsoleteClass> .

obo:OBIB_0000487 a rdfs:Class ;
  rdfs:label "comments related to research authorization process" ;
  rdfs:comment "A textual entity that provides additional information that may be relevant to the research authorization verification process." ;
  rdfs:subClassOf obo:IAO_0000300 .

obo:OBIB_0000320 a rdfs:Class ;
  rdfs:label "microtome blade age" ;
  rdfs:comment "An age that inheres in a microtome blade." ;
  rdfs:subClassOf obo:PATO_0000011 .

obo:OBI_2000013 a rdfs:Class ;
  rdfs:label "arterial blood specimen" ;
  rdfs:comment "A specimen that is derived from some arterial blood" ;
  rdfs:subClassOf obo:OBI_2000009 .

obo:OBIB_0000155 a rdfs:Class ;
  rdfs:label "hysterectomy with left salpingo-oophorectomy" ;
  rdfs:comment "A surgical procedure with the removal of the uterus, cervix, left fallopian tube, and left ovary." ;
  rdfs:subClassOf obo:OBIB_0000716 .

obo:OBIB_0000349 a rdfs:Class ;
  rdfs:label "specimen randomization key ID" ;
  rdfs:comment "A specimen barcode associated with the specific chart (key) used to randomly assign specimens to one of several distinct experimental protocols." ;
  rdfs:subClassOf obo:FLU_0001019 .

obo:OBIB_0000428 a rdfs:Class ;
  rdfs:label "tumor tissue was released to the biobank" ;
  rdfs:comment "An information content entity that is an indicator of whether a tumor tissue specimen was released to a biobank." ;
  rdfs:subClassOf obo:IAO_0000030 .

obo:OMIABIS_0000011 a rdfs:Class ;
  rdfs:label "obsolete contacting" ;
  rdfs:subClassOf <http://www.geneontology.org/formats/oboInOwl#ObsoleteClass> .

obo:OBIB_0000468 a rdfs:Class ;
  rdfs:label "research authorization for post mortem specimen donation not obtained because legally authorized representative was uncomfortable with the risks" ;
  rdfs:comment "A research authorization documentation for post mortem specimen donation in which authorization was not obtained because the the legally authorized representative was uncomfortable with the risks of the request." ;
  rdfs:subClassOf obo:OBIB_0000459 .

obo:OMIABIS_0000040 a rdfs:Class ;
  rdfs:label "obsolete department of sample collection or study contact" ;
  rdfs:subClassOf <http://www.geneontology.org/formats/oboInOwl#ObsoleteClass> .

obo:OBIB_0000513 a rdfs:Class ;
  rdfs:label "current smoker history" ;
  rdfs:comment "A Smoking History in which there is current smoking either on a daily or non-daily basis." ;
  rdfs:subClassOf obo:NCIT_C29719 .

obo:OBI_0000968 a rdfs:Class ;
  rdfs:label "device" ;
  rdfs:comment "A material entity that is designed to perform a function in a scientific investigation, but is not a reagent." ;
  rdfs:subClassOf obo:OBI_0000047 .

obo:OBIB_0000488 a rdfs:Class ;
  rdfs:label "willingness to be contacted for a research study" ;
  rdfs:comment "An information content entity that signifies the willingness of an individual to be contacted for a research study." ;
  rdfs:subClassOf obo:IAO_0000030 .

obo:UBERON_0001159 a rdfs:Class ;
  rdfs:label "sigmoid colon" ;
  rdfs:comment "The part of the large intestine that is closest to the rectum and anus. It forms a loop that averages about 40 cm. in length, and normally lies within the pelvis, but on account of its freedom of movement it is liable to be displaced into the abdominal cavity." ;
  rdfs:subClassOf obo:UBERON_0000064 .

obo:IAO_8000010 a rdfs:Class ;
  rdfs:label "exclusion subset ontology module"@en ;
  rdfs:comment "A subset of an ontology that is intended to be excluded for some purpose. For example, a blacklist of classes."@en ;
  rdfs:subClassOf obo:IAO_8000006 .

obo:NCIT_C43851 a rdfs:Class ;
  rdfs:label "European" ;
  rdfs:comment "Denotes the inhabitants of any of the countries of Europe, a person from there, or their descendants elsewhere." ;
  rdfs:subClassOf obo:OBI_0000181 .

obo:OBIB_0000076 a rdfs:Class ;
  rdfs:label "first blood draw date" ;
  rdfs:comment "A date of specimen collection for the first collection of blood from a donor." ;
  rdfs:subClassOf obo:OBIB_0000714 .

obo:OBI_0002523 a rdfs:Class ;
  rdfs:label "breast specimen" ;
  rdfs:comment "A specimen that is derived from breast." ;
  rdfs:subClassOf obo:OBI_0001479 .

obo:OBIB_0000300 a rdfs:Class ;
  rdfs:label "adherence of duration in clearing agent to FFPE tissue processing SOP" ;
  rdfs:comment "An information content entity that indicates whether the duration in clearing agent followed that prescribed in the FFPE tissue processing SOP." ;
  rdfs:subClassOf obo:IAO_0000030 .

obo:OBI_2000016 a rdfs:Class ;
  rdfs:label "erythrocyte specimen" ;
  rdfs:comment "A specimen that is derived from some erythrocytes" ;
  rdfs:subClassOf obo:OBI_0002599 .

obo:OBIB_0000256 a rdfs:Class ;
  rdfs:label "time of blood plasma specimen transfer to freezer" ;
  rdfs:comment "A data item indicating the time when a blood plasma specimen was transferred to a freezer." ;
  rdfs:subClassOf obo:IAO_0000027 .

obo:OBIB_0000634 a rdfs:Class ;
  rdfs:label "telephone number"@en ;
  rdfs:comment "A telephone number  is a textual entity consisting of a sequence of digits used to call from one telephone line to another in a public switched telephone network."@en ;
  rdfs:subClassOf obo:IAO_0000300 .

obo:OBIB_0000110 a rdfs:Class ;
  rdfs:label "intravenous administration of muscle relaxant" ;
  rdfs:comment "A planned process to administer muscle relaxant intravenously in order to relax skeletal muscles and reduce muscle contraction." ;
  rdfs:subClassOf obo:OBI_0000011 .

obo:OBIB_0000180 a rdfs:Class ;
  rdfs:label "right partial nephrectomy" ;
  rdfs:comment "A surgical procedure to remove part of the right kidney." ;
  rdfs:subClassOf obo:OBIB_0000716 .

obo:UBERON_0002078 a rdfs:Class ;
  rdfs:label "right cardiac atrium" ;
  rdfs:comment "A cardiac atrium that is in the right side of the heart. It receives deoxygenated blood. In mammals, this comes from the superior and inferior vena cava and the coronary sinus, and pumps it into the right ventricle through the tricuspid valve." ;
  rdfs:subClassOf obo:UBERON_0002081 .

obo:OBI_0002123 a rdfs:Class ;
  rdfs:label "IHC slide staining"@en ;
  rdfs:comment "A staining using labeled antibodies, i.e. the analytical part of immunohistochemistry. The staining is applied to fixed specimens on slides to identify biomarkers in tissues."@en ;
  rdfs:subClassOf obo:OBI_0302887 .

obo:OBIB_0000679 a rdfs:Class ;
  rdfs:label "patient registry data"@en ;
  rdfs:comment "A data set of collected secondary data related to patients with a specific diagnosis, condition, or procedure and plays an important role in post marketing surveillance of pharmaceuticals."@en ;
  rdfs:subClassOf obo:IAO_0000100 .

obo:OBIB_0000569 a rdfs:Class ;
  rdfs:label "indication of heroin use" ;
  rdfs:comment "An information content entity  that indicates whether an individual ever used heroin in any manner." ;
  rdfs:subClassOf obo:IAO_0000030 .

obo:OBIB_0000536 a rdfs:Class ;
  rdfs:label "Type II diabetes colorectal cancer risk factor" ;
  rdfs:comment "A colorectal cancer risk factor that is having Type II diabetes mellitus." ;
  rdfs:subClassOf obo:OBIB_0000533 .

obo:OBIB_0000708 a rdfs:Class ;
  rdfs:label "sample collection data entry"@en ;
  rdfs:comment "A planned process that involves the initial entering of data about sample collection into a database."@en ;
  rdfs:subClassOf obo:OBI_0000011 .

obo:OBIB_0000096 a rdfs:Class ;
  rdfs:label "positive serological assay result" ;
  rdfs:comment "A data item that indicates the amount of a serum analyte is at a level above a threshold considered to be present." ;
  rdfs:subClassOf obo:IAO_0000027 .

obo:OBIB_0000639 a rdfs:Class ;
  rdfs:label "postal code of biobank contact"@en ;
  rdfs:comment "The postal code that is part of the postal address of the biobank contact person."@en ;
  rdfs:subClassOf obo:IAO_0000646 .

obo:OBIB_0000271 a rdfs:Class ;
  rdfs:label "time of specimen transport" ;
  rdfs:comment "A data item indicating the time when a specimen was transported to another institution." ;
  rdfs:subClassOf obo:IAO_0000027 .

obo:OBIB_0000026 a rdfs:Class ;
  rdfs:label "obsolete medication role" ;
  rdfs:comment "A role borne by some material entity which can be delivered/administrated into some organism and the role is realized during a clinical treatment process aiming to treat symptoms, signs or diagnosed disease." ;
  rdfs:subClassOf <http://www.geneontology.org/formats/oboInOwl#ObsoleteClass> .

obo:OMRSE_00000211 a rdfs:Class ;
  rdfs:label "male gender identity information content entity"@en ;
  rdfs:comment "A gender identity information content entity that is about some person's identifying as male in gender."@en ;
  rdfs:subClassOf obo:OMRSE_00000209 .

obo:OBIB_0000617 a rdfs:Class ;
  rdfs:label "human biobank"@en ;
  rdfs:comment """A human biobank is a collections of samples of human body substances
(e.g. Tissue, blood, DNA) which are linked to personal data and socio
deographic information about the donors of the material. They have a dual
nature as collections of samples and data.\""""@en ;
  rdfs:subClassOf obo:OBIB_0000616 .

obo:OBI_0002541 a rdfs:Class ;
  rdfs:label "spleen specimen" ;
  rdfs:comment "A specimen that is derived from spleen." ;
  rdfs:subClassOf obo:OBI_0001479 .

obo:OBIB_0000685 a rdfs:Class ;
  rdfs:label "primary diagnosis"@en ;
  rdfs:comment "A diagnosis that is the main reason for the inducement of medical care."@en ;
  rdfs:subClassOf obo:OGMS_0000073 .

obo:OBI_2000009 a rdfs:Class ;
  rdfs:label "bodily fluid specimen" ;
  rdfs:comment "A specimen that is derived from some bodily fluid" ;
  rdfs:subClassOf obo:OBI_0001479 .

obo:OBI_0002537 a rdfs:Class ;
  rdfs:label "thyroid gland specimen" ;
  rdfs:comment "A specimen that is derived from thyroid gland." ;
  rdfs:subClassOf obo:OBI_0001479 .

obo:OBIB_0000222 a rdfs:Class ;
  rdfs:label "blood specimen collection and processing SOP" ;
  rdfs:comment "A standard operating procedure for collection and processing of blood specimens." ;
  rdfs:subClassOf obo:OBIB_0000070 .

obo:OBI_0002191 a rdfs:Class ;
  rdfs:label "courier tracking number"@en ;
  rdfs:comment "A centrally registered identifier symbol assigned by a courier organization in order to track the delivery of an item." ;
  rdfs:subClassOf obo:IAO_0000577 .

obo:OBIB_0000457 a rdfs:Class ;
  rdfs:label "research authorization for post mortem specimen donation" ;
  rdfs:comment "An authorization in which a legally authorized individual is asked to give permission for general research for post mortem specimen donation from a person they represent." ;
  rdfs:subClassOf obo:ICO_0000046 .

obo:OBI_0000684 a rdfs:Class ;
  rdfs:label "specimen collection objective" ;
  rdfs:comment "A objective specification to obtain a material entity for potential use as an input during an investigation." ;
  rdfs:subClassOf obo:IAO_0000005 .

obo:OBIB_0000103 a rdfs:Class ;
  rdfs:label "preoperative intravenous administration of antiemetic" ;
  rdfs:comment "A planned process to administer antiemetic agents intravenously prior to surgery to prevent nausea or vomiting." ;
  rdfs:subClassOf obo:OBI_0000011 .

obo:CHEBI_4717 a rdfs:Class ;
  rdfs:label "droperidol" ;
  rdfs:comment "An organofluorine compound that is haloperidol in which the hydroxy group has been eliminated with the introduction of a double bond in the piperidine ring, and the 4-chlorophenyl group has been replaced by a benzimidazol-2-on-1-yl group. It is used in the management of chemotherapy-induced nausea and vomiting, and in conjunction with an opioid analgesic such as fentanyl to maintain the patient in a calm state of neuroleptanalgesia with indifference to surroundings but still able to cooperate with the surgeon." ;
  rdfs:subClassOf obo:CHEBI_23367 .

obo:OBI_0002373 a rdfs:Class ;
  rdfs:label "aunt clinical history of cancer" ;
  rdfs:comment "A clinical history in which there is a diagnosis of cancer in the female sibling of a parent." ;
  rdfs:subClassOf obo:OBI_0002372 .

obo:OBI_0002196 a rdfs:Class ;
  rdfs:label "Sakura Low profile Accu-Edge microtome blade" ;
  rdfs:comment "A microtome blade that is manufactured by Feather and is disposable. The ultra-sharp blades section specimens without striations, distortion or chattering." ;
  rdfs:subClassOf obo:OBI_0002195 .

obo:OBI_0002501 a rdfs:Class ;
  rdfs:label "bile specimen" ;
  rdfs:comment "A specimen that is derived from bile." ;
  rdfs:subClassOf obo:OBI_2000009 .

obo:OBIB_0000366 a rdfs:Class ;
  rdfs:label "data and time FFPE tissue cassette ID was recorded" ;
  rdfs:comment "A data item indicating the date and time at which the FFPE tissue cassette ID was recorded." ;
  rdfs:subClassOf obo:IAO_0000027 .

obo:OBIB_0000267 a rdfs:Class ;
  rdfs:label "date of specimen placement on dry ice for transport" ;
  rdfs:comment "A data item indicating the calendar date when a specimen was placed on dry ice for transport." ;
  rdfs:subClassOf obo:IAO_0000027 .

obo:OBIB_0000645 a rdfs:Class ;
  rdfs:label "hosted study collection"@en ;
  rdfs:comment "A object aggregate that consists of specimens, participates in a study and is part of a biobank."@en ;
  rdfs:subClassOf obo:BFO_0000027 , obo:OBI_0002076 .

obo:BFO_0000050 a rdf:Property ;
  rdfs:label "part of"@en ;
  rdfs:comment "a core relation that holds between a part and its whole"@en ;
  rdfs:seeAlso <http://www.obofoundry.org/ro/#OBO_REL:part_of> ;
  rdfs:range <https://w3id.org/linkml/Any> .

obo:OBI_0000965 a rdfs:Class ;
  rdfs:label "lyophilized specimen" ;
  rdfs:comment "a specimen that is output of a lyophilization storage process in which specimen is lyophilized for storage." ;
  rdfs:subClassOf obo:OBI_0001472 .

obo:OBIB_0000547 a rdfs:Class ;
  rdfs:label "clinical history of positive blood cultures" ;
  rdfs:comment "A clinical history in which there is a history of positive blood cultures." ;
  rdfs:subClassOf obo:OGMS_0000015 .

obo:OBIB_0000211 a rdfs:Class ;
  rdfs:label "obsolete core needle biopsy" ;
  rdfs:comment "A biopsy that uses a hollow tube that allows extracting a core of tissue for testing. This type of needle biopsy uses a wider needle than does fine-needle aspiration." ;
  rdfs:subClassOf <http://www.geneontology.org/formats/oboInOwl#ObsoleteClass> .

obo:OMIABIS_0000094 a rdfs:Class ;
  rdfs:label "obsolete sample collection or study contact role" ;
  rdfs:subClassOf <http://www.geneontology.org/formats/oboInOwl#ObsoleteClass> .

obo:OBIB_0000417 a rdfs:Class ;
  rdfs:label "temperature in gross room when specimen arrived from OR" ;
  rdfs:comment "A scalar measurement datum that is the output of a temperature measurement assay occurring in a pathology gross room and performed when a specimen arrived from the operating room (OR)." ;
  rdfs:subClassOf obo:IAO_0000032 .

obo:OBI_0000453 a rdfs:Class ;
  rdfs:label "measure function"@en ;
  rdfs:comment "Measure function is a function that is borne by a processed material  and realized in a process in which information about some entity is expressed relative to some reference."@en ;
  rdfs:subClassOf obo:BFO_0000034 .

obo:OMIABIS_0001047 a rdfs:Class ;
  rdfs:label "obsolete case ID" ;
  rdfs:subClassOf <http://www.geneontology.org/formats/oboInOwl#ObsoleteClass> .

obo:OMIABIS_0000022 a rdfs:Class ;
  rdfs:label "obsolete telephone number of biobank contact" ;
  rdfs:subClassOf <http://www.geneontology.org/formats/oboInOwl#ObsoleteClass> .

obo:OBIB_0000558 a rdfs:Class ;
  rdfs:label "clinical history of cancer at death" ;
  rdfs:comment "A clinical history in which there is a current diagnosis of cancer at death." ;
  rdfs:subClassOf obo:OGMS_0000015 .

obo:OBI_0001404 a rdfs:Class ;
  rdfs:label "genetic characteristics information"@en ;
  rdfs:comment "a data item that is about genetic material including polymorphisms, disease alleles, and haplotypes."@en ;
  rdfs:subClassOf obo:IAO_0000027 .

obo:OBI_0600036 a rdfs:Class ;
  rdfs:label "establishing cell culture" ;
  rdfs:comment "a process through which a new type of cell culture or cell line is created, either through the isolation and culture of one or more cells from a fresh source, or the deliberate experimental modification of an existing cell culture (e.g passaging a primary culture to become a secondary culture or line, or the immortalization or stable genetic modification of an existing culture or line)." ;
  rdfs:subClassOf obo:OBI_0000094 .

obo:OBIB_0000289 a rdfs:Class ;
  rdfs:label "equipment maintained as per manufacturer recommendations" ;
  rdfs:comment "An information content entity that indicates whether equipment was maintained following the manufacturers recommendations." ;
  rdfs:subClassOf obo:IAO_0000030 .

obo:OBIB_0000715 a rdfs:Class ;
  rdfs:label "specimen meeting specification"@en ;
  rdfs:comment "All specimens that meet the set parameters to be procured on."@en ;
  rdfs:subClassOf obo:OBI_0100051 .

obo:OMRSE_00000217 a rdfs:Class ;
  rdfs:label "OMB black or African American identity information content entity"@en ;
  rdfs:comment "An OMB racial identity information content entity that is about some person's identifying as black or African American which is intended to mean having origins in any of the black racial groups of Africa."@en ;
  rdfs:subClassOf obo:OMRSE_00000214 .

obo:OBI_0002384 a rdfs:Class ;
  rdfs:label "niece clinical history of cancer" ;
  rdfs:comment "A clinical history in which there is a diagnosis of cancer in a female child of a sibling." ;
  rdfs:subClassOf obo:OBI_0002372 .

obo:OBIB_0000671 a rdfs:Class ;
  rdfs:label "sample collection or study contact person"@en ;
  rdfs:comment "A human being acting as bearing the contact role for a sample collection or a study." ;
  rdfs:subClassOf obo:NCBITaxon_9606 .

obo:GEO_000000400 a rdfs:Class ;
  rdfs:label "governmental organization"@en ;
  rdfs:comment """An organization that governs the people living in a particular geographical region or aggregate of geographical regions.  The geographical region it governs can change over time (such as the westward expansion of the United States and the addition of Hawaii). 

Note: this definition was taken over from \"geopolitical organization\"."""@en ;
  rdfs:subClassOf obo:OBI_0000245 .

obo:BFO_0000038 a rdfs:Class ;
  rdfs:label "one-dimensional temporal region"@en ;
  rdfs:subClassOf obo:BFO_0000008 .

obo:OMIABIS_0001014 a rdfs:Class ;
  rdfs:label "obsolete omics experiment on specimen" ;
  rdfs:subClassOf <http://www.geneontology.org/formats/oboInOwl#ObsoleteClass> .

obo:OBIB_0000282 a rdfs:Class ;
  rdfs:label "comment on specimen integrity after transport" ;
  rdfs:comment "A textual entity that states information about the physical integrity or wholeness of the specimen that is deemed relevant for the specimen transport process." ;
  rdfs:subClassOf obo:IAO_0000300 .

obo:OBIB_0000338 a rdfs:Class ;
  rdfs:label "FFPE tissue section H&E staining protocol" ;
  rdfs:comment "A protocol describing the staining method used during the hematoxylin and eosin (H&E) stained slide preparation of a formalin-fixed paraffin-embedded (FFPE) tissue section." ;
  rdfs:subClassOf obo:OBI_0000272 .

obo:OBIB_0000477 a rdfs:Class ;
  rdfs:label "name of person screening specimen donors" ;
  rdfs:comment "A personal name that designates who performed the screening of a potential specimen donor for a research study." ;
  rdfs:subClassOf obo:IAO_0020015 .

obo:OBIB_0000355 a rdfs:Class ;
  rdfs:label "human brain biobank" ;
  rdfs:comment "A biobank that focuses on the special requirements of the human brain with regards to preservation, handling, and analysis." ;
  rdfs:subClassOf obo:OBIB_0000616 .

obo:NCIT_C16212 a rdfs:Class ;
  rdfs:label "Cancer Therapeutic Procedure" ;
  rdfs:comment "Any intervention for management of a malignant neoplasm." ;
  rdfs:subClassOf obo:OGMS_0000090 .

obo:NCBITaxon_10407 a rdfs:Class ;
  rdfs:label "Hepatitis B virus" ;
  rdfs:subClassOf obo:NCBITaxon_10239 .

obo:OMIABIS_0001031 a rdfs:Class ;
  rdfs:label "obsolete donor patient registry data" ;
  rdfs:subClassOf <http://www.geneontology.org/formats/oboInOwl#ObsoleteClass> .

obo:OBIB_0000294 a rdfs:Class ;
  rdfs:label "adherence of dehydration process duration to FFPE tissue processing SOP" ;
  rdfs:comment "An information content entity that indicates whether duration of the dehydration process followed that prescribed in the FFPE tissue processing SOP." ;
  rdfs:subClassOf obo:IAO_0000030 .

obo:OMIABIS_0001046 a rdfs:Class ;
  rdfs:label "obsolete specimen ID" ;
  rdfs:subClassOf <http://www.geneontology.org/formats/oboInOwl#ObsoleteClass> .

obo:OBIB_0000050 a rdfs:Class ;
  rdfs:label "nicotine e-cigarette"@en ;
  rdfs:comment "A processed material that vaporizes a liquid solution containing nicotine and simulates tobacco smoking by producing an aerosol that resembles smoke." ;
  rdfs:subClassOf obo:OBIB_0000048 .

obo:NCIT_C128458 a rdfs:Class ;
  rdfs:label "Australian/New Zealand Ethnicity" ;
  rdfs:comment "A collection of ethnic geographical categories including Australian and New Zealander." ;
  rdfs:subClassOf obo:HANCESTRO_0004 .

obo:OMIABIS_0001024 a rdfs:Class ;
  rdfs:label "obsolete twin study design" ;
  rdfs:subClassOf <http://www.geneontology.org/formats/oboInOwl#ObsoleteClass> .

obo:PATO_0001241 a rdfs:Class ;
  rdfs:label "physical object quality" ;
  rdfs:comment "A quality which inheres in a continuant." ;
  rdfs:subClassOf obo:BFO_0000019 .

obo:DOID_2152 a rdfs:Class .

obo:OBIB_0000233 a rdfs:Class ;
  rdfs:label "blood specimen container with EDTA" ;
  rdfs:comment "A specimen container for collecting blood and has ethylenediaminetetraacetic acid (EDTA) as an anticoagulant." ;
  rdfs:subClassOf obo:OBI_0002088 .

obo:OBIB_0000659 a rdfs:Class ;
  rdfs:label "fixed tissue specimen"@en ;
  rdfs:comment "A processed specimen that is the output of a fixation process."@en ;
  rdfs:subClassOf obo:OBI_0000953 .

obo:OBIB_0000693 a rdfs:Class ;
  rdfs:label "case control study design"@en ;
  rdfs:comment "A study design that compares two groups of subjects; those with the disease or condtion under study and a similar group of subjects who do not have the condition."@en ;
  rdfs:subClassOf obo:OBI_0500000 .

obo:CHEBI_17303 a rdfs:Class ;
  rdfs:label "morphine" ;
  rdfs:comment "A morphinane alkaloid that is a highly potent opiate analgesic psychoactive drug. Morphine acts directly on the central nervous system (CNS) to relieve pain but has a high potential for addiction, with tolerance and both physical and psychological dependence developing rapidly. Morphine is the most abundant opiate found in Papaver somniferum (the opium poppy)." ;
  rdfs:subClassOf obo:CHEBI_23367 .

obo:OBIB_0000121 a rdfs:Class ;
  rdfs:label "right hemicolectomy" ;
  rdfs:comment "A colectomy that involves removing the cecum, the ascending colon, the hepatic flexure (where the ascending colon joins the transverse colon), the first one-third of the transverse colon, and part of the terminal ileum, along with fat and lymph nodes." ;
  rdfs:subClassOf obo:OAE_0001159 .

obo:OBIB_0000522 a rdfs:Class ;
  rdfs:label "injection-based hormonal birth control method" ;
  rdfs:comment "A birth control method that involves the injection of hormones." ;
  rdfs:subClassOf obo:NCIT_C106501 .

obo:APOLLO_SV_00000033 a rdfs:Class ;
  rdfs:label "counting"@en ;
  rdfs:comment "The planned process of finding the number of elements in a finite set of objects."@en ;
  rdfs:subClassOf obo:OBI_0000011 .

obo:OBIB_0000083 a rdfs:Class ;
  rdfs:label "form data verification process" ;
  rdfs:comment "A planned process to assess the correctness of data entered on a form." ;
  rdfs:subClassOf obo:OBI_0000011 .

obo:OBIB_0000021 a rdfs:Class ;
  rdfs:label "collection packet with specimen and information material"@en ;
  rdfs:comment "A collection packet which contains a container with a specimen and a form filled with information about the collected specimen and specimen source." ;
  rdfs:subClassOf obo:OBIB_0000024 .

obo:OBIB_0000483 a rdfs:Class ;
  rdfs:label "donor's biological sex" ;
  rdfs:comment "Biological sex of the person who bears the role of donor." ;
  rdfs:subClassOf obo:PATO_0000047 .

obo:OBIB_0000215 a rdfs:Class ;
  rdfs:label "medical product expiration date" ;
  rdfs:comment "A data item that indicates the the date determined by appropriate stability testing of the medical product, lot, batch or item after which the product may not meet the appropriate regulatory agencies requirements." ;
  rdfs:subClassOf obo:IAO_0000027 .

obo:OBIB_0000589 a rdfs:Class ;
  rdfs:label "clinical history of gonorrhea" ;
  rdfs:comment "A clinical history in which there is a history of active gonorrhea infection or treatment for gonorrhea in the recent past." ;
  rdfs:subClassOf obo:OGMS_0000015 .

obo:OBI_0002618 a rdfs:Class ;
  rdfs:label "national biomedical registry"@en ;
  rdfs:comment "A national registry that contains information about individuals that was accumulated for a biomedical purpose, such as diagnoses, treatments, or outcomes." ;
  rdfs:subClassOf obo:OBI_0002617 .

obo:IAO_0020010 a rdfs:Class ;
  rdfs:label "dubbing process"@en ;
  rdfs:comment "A dubbing process is a planned process that provides a reference to an individual entity shared by a group of subscribers to refer to that individual entity."@en ;
  rdfs:subClassOf obo:OBI_0000011 .

obo:OBIB_0000603 a rdfs:Class ;
  rdfs:label "clinical history of Amyotrophic Lateral Sclerosis" ;
  rdfs:comment "A clinical history in which there is a history of Amyotrophic Lateral Sclerosis (ALS)" ;
  rdfs:subClassOf obo:OGMS_0000015 .

obo:OBIB_0000138 a rdfs:Class ;
  rdfs:label "albumin volume administered intraoperatively" ;
  rdfs:comment "A measurement datum of the volume of albumin administered during surgery." ;
  rdfs:subClassOf obo:IAO_0000109 .

obo:OBIB_0000015 a rdfs:Class ;
  rdfs:label "freezer rack"@en ;
  rdfs:comment "A device that is part of a freezer for keeping material in the freezer in a defined position and prevents movement." ;
  rdfs:subClassOf obo:OBI_0000968 .

obo:OBIB_0000260 a rdfs:Class ;
  rdfs:label "comment from blood specimen processing" ;
  rdfs:comment "A textual entity that states additional information about the blood specimen or donor that is deemed relevant for specimen processing." ;
  rdfs:subClassOf obo:IAO_0000300 .

obo:OBIB_0000443 a rdfs:Class ;
  rdfs:label "desired plasma and serum aliquots were obtained" ;
  rdfs:comment "An information content entity that is an indicator of whether the desired plasma and serum aliquots were obtained from a specimen donor." ;
  rdfs:subClassOf obo:IAO_0000030 .

obo:OBI_0002378 a rdfs:Class ;
  rdfs:label "sister clinical history of cancer" ;
  rdfs:comment "A clinical history in which there is a diagnosis of cancer in a female sibling." ;
  rdfs:subClassOf obo:OBI_0002372 .

obo:OBIB_0000364 a rdfs:Class ;
  rdfs:label "FFPE fixation delay protocol" ;
  rdfs:comment "A FFPE fixation protocol that specifies the planned delay to fixation time." ;
  rdfs:subClassOf obo:OBIB_0000363 .

obo:OBIB_0000455 a rdfs:Class ;
  rdfs:label "activity related to a particular specimen donor was stopped because tissue was benign" ;
  rdfs:comment "An activity related to a particular specimen donor was stopped that is because the tissue was benign." ;
  rdfs:subClassOf obo:OBIB_0000451 .

obo:NCIT_C126535 a rdfs:Class ;
  rdfs:label "Australian" ;
  rdfs:comment "Denotes a person whose ancestry is in the country or continent of Australia." ;
  rdfs:subClassOf obo:OBI_0000181 .

obo:OMIABIS_0000057 a rdfs:Class ;
  rdfs:label "obsolete microdissected specimen" ;
  rdfs:subClassOf <http://www.geneontology.org/formats/oboInOwl#ObsoleteClass> .

obo:OBIB_0000305 a rdfs:Class ;
  rdfs:label "FFPE paraffin impregnation method" ;
  rdfs:comment "A protocol for the paraffin impregnation step of a formalin-fixed paraffin-embedded (FFPE) process." ;
  rdfs:subClassOf obo:OBI_0000272 .

obo:HANCESTRO_0463 a rdfs:Class ;
  rdfs:label "American"@en ;
  rdfs:subClassOf obo:HANCESTRO_0004 .

obo:OBI_0002395 a rdfs:Class ;
  rdfs:label "number of live births" ;
  rdfs:comment "A measurement datum of the total number of live births a female has had." ;
  rdfs:subClassOf obo:IAO_0000109 .

obo:OBIB_0000385 a rdfs:Class ;
  rdfs:label "specimen image ID" ;
  rdfs:comment "An identifier that specifically identifies a particular specimen image." ;
  rdfs:subClassOf obo:IAO_0020000 .

obo:OBIB_0000345 a rdfs:Class ;
  rdfs:label "comment on preparation of FFPE H&E stained slide" ;
  rdfs:comment "A textual entity that states information relevant to the preparation of a formalin-fixed paraffin-embedded (FFPE) hematoxylin and eosin (H&E) stained slide." ;
  rdfs:subClassOf obo:IAO_0000300 .

obo:OBIB_0000047 a rdfs:Class ;
  rdfs:label "chewing tobacco"@en ;
  rdfs:comment "A processed material which is a kind of smokeless tobacco product consumed by placing a portion of the tobacco between the cheek and gum or upper lip teeth and chewing." ;
  rdfs:subClassOf obo:OBIB_0000057 .

obo:OBIB_0000072 a rdfs:Class ;
  rdfs:label "tissue procurement SOP" ;
  rdfs:comment "A standard operating procedure for collecting specimens from organism." ;
  rdfs:subClassOf obo:OBIB_0000070 .

obo:UBERON_0001797 a rdfs:Class ;
  rdfs:label "vitreous humor" ;
  rdfs:comment "A transparent, semigelatinous substance that fills the cavity behind the crystalline lens of the eye and in front of the retina." ;
  rdfs:subClassOf obo:UBERON_0000463 .

obo:OBI_0002552 a rdfs:Class ;
  rdfs:label "testis specimen" ;
  rdfs:comment "A specimen that is derived from testis." ;
  rdfs:subClassOf obo:OBI_0001479 .

obo:OBI_0001580 a rdfs:Class ;
  rdfs:label "material transport service" ;
  rdfs:comment "A service in which a service provider facilitates the transport of some material entity to a specified destination for the service consumer." ;
  rdfs:subClassOf obo:OBI_0001528 .

obo:OBIB_0000344 a rdfs:Class ;
  rdfs:label "manual FFPE tissue section H&E cover slipping" ;
  rdfs:comment "A planned process involving the manual performance of the FFPE tissue section H&E cover slip protocol." ;
  rdfs:subClassOf obo:OBI_0000011 .

obo:NCIT_C7281 a rdfs:Class ;
  rdfs:label "Borderline Ovarian Seromucinous Tumor/Atypical Proliferative Ovarian Seromucinous Tumor" ;
  rdfs:comment "A low grade, non-invasive ovarian epithelial neoplasm characterized by the presence of atypical neoplastic serous and mucinous cells." ;
  rdfs:subClassOf obo:DOID_2152 .

obo:OBIB_0000163 a rdfs:Class ;
  rdfs:label "left salpingo-oophorectomy" ;
  rdfs:comment "A surgical procedure to remove the left ovary and left fallopian tube." ;
  rdfs:subClassOf obo:OBIB_0000716 .

obo:OMIABIS_0000027 a rdfs:Class ;
  rdfs:label "obsolete postal code of biobank contact" ;
  rdfs:subClassOf <http://www.geneontology.org/formats/oboInOwl#ObsoleteClass> .

obo:IAO_0000129 a rdfs:Class ;
  rdfs:label "version number"@en ;
  rdfs:comment "A version number is an information content entity which is a sequence of characters borne by part of each of a class of manufactured products or its packaging and indicates its order within a set of other products having the same name."@en ;
  rdfs:subClassOf obo:IAO_0000028 .

obo:OBIB_0000654 a rdfs:Class ;
  rdfs:label "intra-settlement specification part of address of sample collection or study contact"@en ;
  rdfs:comment "An intra-settlement specification part of address that is part of a sample collection or study contact's postal address."@en ;
  rdfs:subClassOf obo:OBIB_0000643 .

obo:OBI_0002400 a rdfs:Class ;
  rdfs:label "neither hysterectomy nor oophorectomy history" ;
  rdfs:comment "A gynecologic surgery history in which a woman has not had either a hysterectomy or an oophorectomy." ;
  rdfs:subClassOf obo:OBI_0002397 .

obo:OBIB_0000710 a rdfs:Class ;
  rdfs:label "survey execution"@en ;
  rdfs:comment "A planned process that realizes the concretization of a survey to generate an output(survey data.)"@en ;
  rdfs:subClassOf obo:OBI_0000011 .

obo:OMIABIS_0001029 a rdfs:Class ;
  rdfs:label "obsolete age interval information for sampled donors" ;
  rdfs:subClassOf <http://www.geneontology.org/formats/oboInOwl#ObsoleteClass> .

obo:UBERON_0001388 a rdfs:Class ;
  rdfs:label "gastrocnemius" ;
  rdfs:comment "The most superficial muscle of the triceps surae group, in the posterior portion of the lower hindleg." ;
  rdfs:subClassOf obo:UBERON_0001134 .

obo:CHEBI_4910 a rdfs:Class ;
  rdfs:label "etomidate" ;
  rdfs:comment "The ethyl ester of 1-[(1R)-1-phenylethyl]-1H-imidazole-5-carboxylic acid. It is an intravenous general anaesthetic with no analgesic activity." ;
  rdfs:subClassOf obo:CHEBI_23367 .

obo:IAO_0000178 a rdfs:Class ;
  rdfs:label "material information bearer"@en ;
  rdfs:comment "A material entity in which a concretization of an information content entity inheres."@en ;
  rdfs:subClassOf obo:BFO_0000040 .

obo:UBERON_0002097 a rdfs:Class ;
  rdfs:label "skin of body" ;
  rdfs:comment "The organ covering the body that consists of the dermis and epidermis." ;
  rdfs:subClassOf obo:UBERON_0000465 .

obo:OBIB_0000144 a rdfs:Class ;
  rdfs:label "specimen donor intraoperative blood loss at end of surgery volume measurement datum" ;
  rdfs:comment "A specimen donor intraoperative blood loss volume measurement datum obtained at the end of surgery." ;
  rdfs:subClassOf obo:OBIB_0000142 .

obo:OMIABIS_0000016 a rdfs:Class ;
  rdfs:label "obsolete postal address of biobank contact person" ;
  rdfs:subClassOf <http://www.geneontology.org/formats/oboInOwl#ObsoleteClass> .

obo:UBERON_0001567 a rdfs:Class ;
  rdfs:label "cheek" ;
  rdfs:comment "A fleshy subdivision of one side of the face bounded by an eye, ear and the nose." ;
  rdfs:subClassOf obo:UBERON_0000465 .

obo:OBIB_0000665 a rdfs:Class ;
  rdfs:label "frozen tissue slide specimen"@en ;
  rdfs:comment "A frozen specimen that has been sliced from a tissue block into thin layers that are placed on a glass to be examined under a microscope."@en ;
  rdfs:subClassOf obo:OBI_0000922 .

<http://www.w3.org/2003/11/swrl#Variable> a rdfs:Class .

obo:OBIB_0000149 a rdfs:Class ;
  rdfs:label "ascites fluid from specimen donor during surgery volume measurement datum" ;
  rdfs:comment "A measurement datum of the volume of ascites fluid collected from the specimen donor during surgery." ;
  rdfs:subClassOf obo:IAO_0000109 .

obo:OBIB_0000292 a rdfs:Class ;
  rdfs:label "adherence of alcohol stage duration to FFPE tissue processing SOP" ;
  rdfs:comment "An information content entity that indicates whether duration of the alcohol stage followed that prescribed in the FFPE tissue processing SOP." ;
  rdfs:subClassOf obo:IAO_0000030 .

obo:FMA_19973 a rdfs:Class ;
  rdfs:label "Posterior wall of vagina" ;
  rdfs:subClassOf obo:UBERON_0000064 .

obo:BFO_0000141 a rdfs:Class ;
  rdfs:label "immaterial entity"@en ;
  rdfs:subClassOf obo:BFO_0000004 .

obo:OBIB_0000379 a rdfs:Class ;
  rdfs:label "date and time FFPE tissue cassette transferred to storage" ;
  rdfs:comment "A data item indicating the date and time when a tissue cassette was transferred to storage after a formalin-fixed paraffin-embedded (FFPE) process." ;
  rdfs:subClassOf obo:IAO_0000027 .

obo:UBERON_0000955 a rdfs:Class ;
  rdfs:label "brain" ;
  rdfs:comment "The brain is the center of the nervous system in all vertebrate, and most invertebrate, animals. Some primitive animals such as jellyfish and starfish have a decentralized nervous system without a brain, while sponges lack any nervous system at all. In vertebrates, the brain is located in the head, protected by the skull and close to the primary sensory apparatus of vision, hearing, balance, taste, and smell[WP]." ;
  rdfs:subClassOf obo:UBERON_0000465 .

obo:OBIB_0000374 a rdfs:Class ;
  rdfs:label "measurement of time between FFPE tissue processor cycle completion and embedding" ;
  rdfs:comment "A time measurement datum that is the result of measuring the time between FFPE tissue processor cycle completion and embedding in a formalin-fixed paraffin-embedded (FFPE) process." ;
  rdfs:subClassOf obo:IAO_0000416 .

obo:CL_0000738 a rdfs:Class ;
  rdfs:label "leukocyte" ;
  rdfs:comment "An achromatic cell of the myeloid or lymphoid lineages capable of ameboid movement, found in blood or other tissue." ;
  rdfs:subClassOf obo:CL_0000000 .

obo:OBIB_0000562 a rdfs:Class ;
  rdfs:label "clinical history of encephalitis" ;
  rdfs:comment "A clinical history in which there was active encephalitis at death." ;
  rdfs:subClassOf obo:OGMS_0000015 .

obo:NCBITaxon_2157 a rdfs:Class ;
  rdfs:label "Archaea" ;
  rdfs:subClassOf obo:OBI_0100026 .

obo:OMIABIS_0000005 a rdfs:Class ;
  rdfs:label "obsolete biobank idenfier with ISO 3166-1 alpha-2 code" ;
  rdfs:subClassOf <http://www.geneontology.org/formats/oboInOwl#ObsoleteClass> .

obo:OBI_0002512 a rdfs:Class ;
  rdfs:label "bone marrow specimen" ;
  rdfs:comment "A specimen that is derived from bone marrow." ;
  rdfs:subClassOf obo:OBI_0001479 .

obo:OBI_0002371 a rdfs:Class ;
  rdfs:label "diagnosis of cancer" ;
  rdfs:comment "A diagnosis that is an assertion that a patient who is the subject of a diagnostic process has cancer." ;
  rdfs:subClassOf obo:OGMS_0000073 .

obo:IAO_0000308 a rdfs:Class ;
  rdfs:label "figure"@en ;
  rdfs:comment "An information content entity consisting of a two dimensional arrangement of information content entities such that the arrangement itself is about something."@en ;
  rdfs:subClassOf obo:IAO_0000030 .

obo:IAO_8000007 a rdfs:Class ;
  rdfs:label "curation subset ontology module"@en ;
  rdfs:comment "A subset ontology that is intended as a whitelist for curators using the ontology. Such a subset will exclude classes that curators should not use for curation."@en ;
  rdfs:subClassOf obo:IAO_8000006 .

obo:UBERON_0036214 a rdfs:Class ;
  rdfs:label "rectosigmoid junction" ;
  rdfs:comment "An anatomical junction that is between the sigmoid colon and rectum." ;
  rdfs:subClassOf obo:UBERON_0000064 .

obo:UBERON_0001088 a rdfs:Class ;
  rdfs:label "urine" ;
  rdfs:comment "Excretion that is the output of a kidney." ;
  rdfs:subClassOf obo:UBERON_0000463 .

obo:OBIB_0000578 a rdfs:Class ;
  rdfs:label "clinical history of blue or purple spots on skin or mucous membranes" ;
  rdfs:comment "A clinical history in which there is a of blue or purple spots on the skin or mucus membranes (typical of Kaposi's sarcoma)." ;
  rdfs:subClassOf obo:OGMS_0000015 .

obo:CHEBI_38877 a rdfs:Class ;
  rdfs:label "intravenous anaesthetic" ;
  rdfs:subClassOf obo:CHEBI_38867 .

obo:OBIB_0000466 a rdfs:Class ;
  rdfs:label "research authorization for post mortem specimen donation not obtained because legally authorized representative felt too distraught" ;
  rdfs:comment "A research authorization documentation for post mortem specimen donation in which authorization was not obtained because the the legally authorized representative felt too distraught." ;
  rdfs:subClassOf obo:OBIB_0000459 .

obo:OBIB_0000208 a rdfs:Class ;
  rdfs:label "specimen gross appearance" ;
  rdfs:comment "A data item on manifestations of disease produced from macroscopic analysis of a specimen." ;
  rdfs:subClassOf obo:IAO_0000027 .

obo:OBI_0002389 a rdfs:Class ;
  rdfs:label "clinical history of repeated HIV assays" ;
  rdfs:comment "A clinical history in which there is repeated reactive screening assays for human immunodeficiency virus (1 or 2) antibodies regardless of the results of supplemental assays." ;
  rdfs:subClassOf obo:OGMS_0000015 .

obo:OBIB_0000054 a rdfs:Class ;
  rdfs:label "smoking end date"@en ;
  rdfs:comment "A time measurement datum which is the end date of a smoking behavior." ;
  rdfs:subClassOf obo:IAO_0000416 .

obo:OBI_0001157 a rdfs:Class ;
  rdfs:label "age since hatching measurement datum"@en ;
  rdfs:comment "An age measurement datum that is the result of the measurement of the age of an organism since hatching, the process of emergence from an egg." ;
  rdfs:subClassOf obo:OBI_0001167 .

obo:OBIB_0000451 a rdfs:Class ;
  rdfs:label "activity related to a particular specimen donor was stopped." ;
  rdfs:comment "An information content entity that is an indicator of whether activity related to a particular specimen donor was stopped." ;
  rdfs:subClassOf obo:IAO_0000030 .

obo:OBIB_0000322 a rdfs:Class ;
  rdfs:label "preparation of FFPE block face for sectioning protocol" ;
  rdfs:comment "A protocol describing the preparation on the faced block prior to sectioning of a formalin-fixed paraffin-embedded (FFPE) tissue." ;
  rdfs:subClassOf obo:OBI_0000272 .

obo:OBIB_0000297 a rdfs:Class ;
  rdfs:label "FFPE dehydration process temperature" ;
  rdfs:comment "A scalar measurement datum that is the output of a temperature measurement assay performed on a specimen in alcohol during the dehydration process  in a formalin-fixed paraffin-embedded (FFPE) process." ;
  rdfs:subClassOf obo:IAO_0000032 .

obo:OBIB_0000721 a rdfs:Class ;
  rdfs:label "specimen ID"@en ;
  rdfs:comment "A proper name that identifies a specimen and is usually in form of a label included in the specimen cassette."@en ;
  rdfs:subClassOf obo:IAO_0020000 .

obo:OBIB_0000166 a rdfs:Class ;
  rdfs:label "abdominal surgical method" ;
  rdfs:comment "A surgical method in which operations are performed through the abdomen." ;
  rdfs:subClassOf obo:OBIB_0000165 .

obo:OBI_0002153 a rdfs:Class ;
  rdfs:label "EBV IgM antibody assay" ;
  rdfs:comment "An antigen specific antibodies assay that is meant to detect immunoglobulin M (IgM) antibodies that bind to Epstein-Barr virus (EBV) antigens." ;
  rdfs:subClassOf obo:OBI_0002145 .

obo:OBIB_0000450 a rdfs:Class ;
  rdfs:label "all requirements for an investigation are met enabling release of specimen for shipment." ;
  rdfs:comment "An information content entity that is an indicator of whether all requirements for an investigation were met such that a specimen from a particular donor is released for shipment." ;
  rdfs:subClassOf obo:IAO_0000030 .

obo:OBI_0001905 a rdfs:Class ;
  rdfs:label "secondary cultured cell population" ;
  rdfs:comment "A cultured cell population that is derived through one or more passages in culture." ;
  rdfs:subClassOf obo:OBI_0100060 .

obo:OBI_0000450 a rdfs:Class ;
  rdfs:label "regulatory agency"@en ;
  rdfs:comment "A regulatory agency is a organization that has responsibility over or for  the legislation (acts and regulations) for a given sector of the government."@en ;
  rdfs:subClassOf obo:OBI_0000245 .

obo:OBIB_0000191 a rdfs:Class ;
  rdfs:label "right pneumonectomy" ;
  rdfs:comment "A surgical procedure performed to remove an entire right lung" ;
  rdfs:subClassOf obo:OBIB_0000716 .

obo:CL_0000010 a rdfs:Class ;
  rdfs:label "cultured cell" ;
  rdfs:comment "A cell in vitro that is or has been maintained or propagated as part of a cell culture." ;
  rdfs:subClassOf obo:CL_0000578 .

obo:OMIABIS_0001035 a rdfs:Class ;
  rdfs:label "obsolete survey execution" ;
  rdfs:subClassOf <http://www.geneontology.org/formats/oboInOwl#ObsoleteClass> .

obo:PATO_0000918 a rdfs:Class ;
  rdfs:label "volume" ;
  rdfs:comment "A 3-D extent quality inhering in a bearer by virtue of the bearer's amount of 3-dimensional space it occupies." ;
  rdfs:subClassOf obo:PATO_0001710 .

obo:OBIB_0000334 a rdfs:Class ;
  rdfs:label "FFPE tissue section H&E staining and mounting SOP" ;
  rdfs:comment "A standard operating procedure for the hematoxylin and eosin (H&E) staining and slide mounting of a formalin-fixed paraffin-embedded (FFPE) tissue section." ;
  rdfs:subClassOf obo:OBIB_0000070 .

obo:OBIB_0000278 a rdfs:Class ;
  rdfs:label "temperature of specimen collection packet at time of receipt" ;
  rdfs:comment "A scalar measurement datum that is the output of a temperature measurement assay performed on a collection packet when it is received with a specimen." ;
  rdfs:subClassOf obo:IAO_0000032 .

obo:OBIB_0000410 a rdfs:Class ;
  rdfs:label "name of data entry person for local pathology review form" ;
  rdfs:comment "A personal name that designates the person who performed the data entry process for filling in a local pathology review form." ;
  rdfs:subClassOf obo:IAO_0020015 .

obo:OBI_0002136 a rdfs:Class ;
  rdfs:label "RNA Integrity Number calculation"@en ;
  rdfs:comment "A data transformation using the RIN algorithm to generate a quality measure of RNA based on features from an electrophoretic trace." ;
  rdfs:subClassOf obo:OBI_0200000 .

obo:NCIT_C81229 a rdfs:Class ;
  rdfs:label "Alcohol Use History" ;
  rdfs:comment "A description of an individual's current and past experience with alcoholic beverage consumption." ;
  rdfs:subClassOf obo:IAO_0000030 .

obo:OBIB_0000490 a rdfs:Class ;
  rdfs:label "authorization documentation for postmortem specimen donation for a specified purpose" ;
  rdfs:comment "An authorization documentation for postmortem specimen donation in which specimens are to be used for a specified purpose (e.g., transplantation, research, education)." ;
  rdfs:subClassOf obo:ICO_0000075 .

obo:OBIB_0000511 a rdfs:Class ;
  rdfs:label "duration of greater than moderate alcohol consumption prior to enrollment" ;
  rdfs:comment "A time measurement datum that is the result of measuring the duration of greater than moderate alcohol consumption (more than 2 drinks per day for a man or more than 1 drink per day for a woman) prior to study enrollment." ;
  rdfs:subClassOf obo:IAO_0000416 .

obo:OBIB_0000401 a rdfs:Class ;
  rdfs:label "non-cellular component of tumor slide specimen description" ;
  rdfs:comment "A textual entity that describes the non-cellular component of a tumor slide specimen." ;
  rdfs:subClassOf obo:IAO_0000300 .

obo:IAO_0000028 a rdfs:Class ;
  rdfs:label "symbol"@en ;
  rdfs:comment "An information content entity that is a mark(s) or character(s) used as a conventional representation of another entity."@en ;
  rdfs:subClassOf obo:IAO_0000030 .

obo:OBI_0002356 a rdfs:Class ;
  rdfs:label "performance status value specification" ;
  rdfs:comment "A categorical value specification that is an assessment of a participant's performance status (general well-being and activities of daily life)." ;
  rdfs:subClassOf obo:OBI_0001930 .

obo:OMIABIS_0001003 a rdfs:Class ;
  rdfs:label "obsolete survey data" ;
  rdfs:subClassOf <http://www.geneontology.org/formats/oboInOwl#ObsoleteClass> .

obo:BFO_0000011 a rdfs:Class ;
  rdfs:label "spatiotemporal region"@en ;
  rdfs:subClassOf obo:BFO_0000003 .

obo:OBIB_0000461 a rdfs:Class ;
  rdfs:label "research authorization documentation for post mortem specimen donation that is affirmative" ;
  rdfs:comment "A research authorization documentation for post mortem specimen donation establishing agreement for post-mortem donation and use in general research." ;
  rdfs:subClassOf obo:OBIB_0000459 .

obo:OBI_0002147 a rdfs:Class ;
  rdfs:label "HIV group O antibody assay" ;
  rdfs:comment "An antigen specific antibodies assay that is meant to detect antibodies that bind to human immunodeficiency virus (HIV) group O antigens." ;
  rdfs:subClassOf obo:OBI_0002145 .

obo:OMIABIS_0001042 a rdfs:Class ;
  rdfs:label "obsolete specimen preparation contact" ;
  rdfs:subClassOf <http://www.geneontology.org/formats/oboInOwl#ObsoleteClass> .

obo:OBIB_0000311 a rdfs:Class ;
  rdfs:label "fresh paraffin" ;
  rdfs:comment "A paraffin that has not been previously used or recycled." ;
  rdfs:subClassOf obo:DRON_00015464 .

obo:OBIB_0000421 a rdfs:Class ;
  rdfs:label "gross appearance of disease in resected tissue" ;
  rdfs:comment "An information content entity that is an indicator of whether gross appearance of disease was observed in a resected tissue specimen." ;
  rdfs:subClassOf obo:IAO_0000030 .

obo:BFO_0000040 a rdfs:Class ;
  rdfs:label "material entity"@en ;
  rdfs:comment "An independent continuant that is spatially extended whose identity is independent of that of other entities and can be maintained through time."@en ;
  rdfs:subClassOf obo:BFO_0000004 .

obo:OBI_0400168 a rdfs:Class ;
  rdfs:label "microtome" ;
  rdfs:comment "A microtome is a mechanical instrument used to cut biological specimens into very thin segments for further treatment (e.g. ISH) and ultimately microscopic or histologic examination. Most microtomes provide cooling facilities (cryo-microtome) and use a steel blade to cut a slice of defined thickness. Some are automatic, and some are driven by hand." ;
  rdfs:subClassOf obo:OBI_0000932 .

obo:OBI_0001168 a rdfs:Class ;
  rdfs:label "age since fertilization measurement datum"@en ;
  rdfs:comment "An age measurement datum that is the result of the measurement of the age of an organism since fertilization, the process of the union of gametes of opposite sexes during the process of sexual reproduction to form a zygote." ;
  rdfs:subClassOf obo:OBI_0001167 .

obo:OBI_0001936 a rdfs:Class ;
  rdfs:label "molecular-labeled material" ;
  rdfs:comment "a material entity that is the specified output of an addition of molecular label process that aims to label some molecular target to allow for its detection in a detection of molecular label assay" ;
  rdfs:subClassOf obo:BFO_0000040 , obo:OBI_0000047 .

obo:IAO_0020021 a rdfs:Class ;
  rdfs:label "identity document"@en ;
  rdfs:comment "A document that denotes some identity and is concretized by the bearer of some credential role."@en ;
  rdfs:subClassOf obo:IAO_0000310 .

obo:OBIB_0000520 a rdfs:Class ;
  rdfs:label "comment from clinical data entry form" ;
  rdfs:comment "A textual entity that states additional information relevant to the filling out of a clinical data entry form." ;
  rdfs:subClassOf obo:IAO_0000300 .

obo:OBIB_0000065 a rdfs:Class ;
  rdfs:label "rectal temperature measurement assay" ;
  rdfs:comment "An internal body temperature measurement assay where the thermometer is placed in the rectum." ;
  rdfs:subClassOf obo:OBIB_0000063 .

obo:OBI_0000927 a rdfs:Class ;
  rdfs:label "lyophilization storage" ;
  rdfs:comment "a storage process with input material entity and output freeze dried material for long time storage" ;
  rdfs:subClassOf obo:OBI_0302893 .

obo:OBI_0500027 a rdfs:Class ;
  rdfs:label "inclusion criterion"@en ;
  rdfs:comment "an inclusion criterion (rule) is_a *eligibility criterion*  which defines and states a condition which, if met, makes an entity suitable for a given task or participation in a given process. For instance, in a study protocol, inclusion criteria indicate the conditions that prospective subjects MUST meet to be eligible for participation in a study."@en ;
  rdfs:subClassOf obo:OBI_0500026 .

obo:OMIABIS_0001028 a rdfs:Class ;
  rdfs:label "obsolete sample handling summary" ;
  rdfs:subClassOf <http://www.geneontology.org/formats/oboInOwl#ObsoleteClass> .

obo:OBIB_0000713 a rdfs:Class ;
  rdfs:label "specimen measurement"@en ;
  rdfs:comment "A measurement datum that is the result of measurement of the three dimensions of a specimen."@en ;
  rdfs:subClassOf obo:IAO_0000109 .

obo:OMIABIS_0000912 a rdfs:Class ;
  rdfs:label "obsolete addition of molecular label" ;
  rdfs:subClassOf <http://www.geneontology.org/formats/oboInOwl#ObsoleteClass> .

obo:IAO_0000577 a rdfs:Class ;
  rdfs:label "centrally registered identifier symbol"@en ;
  rdfs:comment "A symbol that is part of a CRID and that is sufficient to look up a record from the CRID's registry."@en ;
  rdfs:subClassOf obo:IAO_0000028 .

obo:OBIB_0000013 a rdfs:Class ;
  rdfs:label "cryovial box"@en ;
  rdfs:comment "A device that is intended to hold cryovials." ;
  rdfs:subClassOf obo:OBI_0000967 .

obo:OBIB_0000352 a rdfs:Class ;
  rdfs:label "serology alert associated with specimen donor" ;
  rdfs:comment "A textual entity that is a notification within a clinical data repository that specimen donor serology results include positive infectious disease data." ;
  rdfs:subClassOf obo:IAO_0000300 .

obo:OMIABIS_0001005 a rdfs:Class ;
  rdfs:label "obsolete date of data update" ;
  rdfs:subClassOf <http://www.geneontology.org/formats/oboInOwl#ObsoleteClass> .

obo:OBIB_0000313 a rdfs:Class ;
  rdfs:label "total time FFPE freshly poured blocks were cooled" ;
  rdfs:comment "A time measurement datum that is the result of measuring the total time that freshly poured blocks were cooled in the formalin-fixed paraffin-embedded (FFPE) process." ;
  rdfs:subClassOf obo:IAO_0000416 .

obo:OBIB_0000674 a rdfs:Class ;
  rdfs:label "mixed state specimen datum"@en ;
  rdfs:comment "A specimen disease state datum that specifies that the specimen in question consists of partially normal tissue and a disorder."@en ;
  rdfs:subClassOf obo:OBIB_0000672 .

obo:OBIB_0000572 a rdfs:Class ;
  rdfs:label "an indication of illegal injectable drug use" ;
  rdfs:comment "An information content entity that indicates whether an individual recently used injectable drugs for non-medical purposes in the recent past." ;
  rdfs:subClassOf obo:IAO_0000030 .

obo:OBI_0000070 a rdfs:Class ;
  rdfs:label "assay"@en ;
  rdfs:comment "A planned process with the objective to produce information about the material entity that is the evaluant, by physically examining it or its proxies."@en ;
  rdfs:subClassOf obo:OBI_0000011 .

obo:CHEBI_36333 a rdfs:Class ;
  rdfs:label "local anaesthetic" ;
  rdfs:comment "Any member of a group of drugs that reversibly inhibit the propagation of signals along nerves. Wide variations in potency, stability, toxicity, water-solubility and duration of action determine the route used for administration, e.g. topical, intravenous, epidural or spinal block." ;
  rdfs:subClassOf obo:CHEBI_38867 .

obo:OBIB_0000607 a rdfs:Class ;
  rdfs:label "indication of time in jail" ;
  rdfs:comment "An information content entity in which there is an indication of whether an individual spent more than 72 hours in a correction/detention center in the recent past." ;
  rdfs:subClassOf obo:IAO_0000030 .

obo:OBIB_0000198 a rdfs:Class ;
  rdfs:label "minimum number of aliquots not banked" ;
  rdfs:comment "A reason for not banking pre-operative blood specimen which is a minimum number of aliquots was not banked." ;
  rdfs:subClassOf obo:OBIB_0000195 .

obo:OMIABIS_0000043 a rdfs:Class ;
  rdfs:label "obsolete intra-settlement specification part of address of sample collection or study contact" ;
  rdfs:subClassOf <http://www.geneontology.org/formats/oboInOwl#ObsoleteClass> .

obo:OBIB_0000393 a rdfs:Class ;
  rdfs:label "percentage of cross-sectional surface area of entire slide composed of tumor focus" ;
  rdfs:comment "A data item that is the result of determining the percentage of cross-sectional surface area of an entire specimen slide composed of tumor focus including necrotic tumor." ;
  rdfs:subClassOf obo:IAO_0000027 .

obo:OBI_0000275 a rdfs:Class ;
  rdfs:label "analyte role"@en ;
  rdfs:comment "A measurand role borne by a molecular entity or an atom and realized in an analyte assay which achieves the objective to measure the magnitude/concentration/amount of the analyte in the entity bearing evaluant role."@en ;
  rdfs:subClassOf obo:OBI_0002444 .

obo:RO_0000081 a rdf:Property ;
  rdfs:label "role of"@en ;
  rdfs:comment "a relation between a role and an independent continuant (the bearer), in which the role specifically depends on the bearer for its existence"@en ;
  rdfs:range <https://w3id.org/linkml/Any> ;
  rdfs:subPropertyOf obo:RO_0000052 .

obo:OBI_0002411 a rdfs:Class ;
  rdfs:label "indeterminate menopausal status" ;
  rdfs:comment "A menopausal status that is neither pre- nor post-menopausal." ;
  rdfs:subClassOf obo:OBI_0002410 .

obo:OMIABIS_0000020 a rdfs:Class ;
  rdfs:label "obsolete biobank's unique resource locator" ;
  rdfs:subClassOf <http://www.geneontology.org/formats/oboInOwl#ObsoleteClass> .

obo:HANCESTRO_0004 a rdfs:Class ;
  rdfs:label "ancestry category" ;
  rdfs:comment "Population category defined using ancestry informative markers (AIMs) based on genetic/genomic data" ;
  rdfs:subClassOf obo:OBI_0000181 .

obo:OBIB_0000187 a rdfs:Class ;
  rdfs:label "right lung lobectomy" ;
  rdfs:comment "A surgical procedure to remove one of the lobes of the right lung." ;
  rdfs:subClassOf obo:OBIB_0000716 .

obo:OBIB_0000368 a rdfs:Class ;
  rdfs:label "placement of tissue cassette in FFPE fixative delay duration" ;
  rdfs:comment "A time measurement datum that is the result of measuring the duration of the the planned delay of placing the tissue cassette in fixative in the formalin-fixed paraffin-embedded (FFPE) process." ;
  rdfs:subClassOf obo:IAO_0000416 .

obo:ICO_0000148 a rdfs:Class ;
  rdfs:label "candidate ineligible for study role"@en ;
  rdfs:comment "A role inhering in a participant who does not meet all eligibility criteria defined within the study protocol."@en ;
  rdfs:subClassOf obo:ICO_0000146 .

obo:OBI_2000000 a rdfs:Class ;
  rdfs:label "uterine cervix specimen" ;
  rdfs:comment "A specimen that is derived from some uterine cervix" ;
  rdfs:subClassOf obo:OBI_0001479 .

obo:OBIB_0000206 a rdfs:Class ;
  rdfs:label "beginning time of parent specimen dissection." ;
  rdfs:comment "A data item indicating the time that the dissection of a specimen for specimen family creation began." ;
  rdfs:subClassOf obo:IAO_0000027 .

obo:OMIABIS_0000032 a rdfs:Class ;
  rdfs:label "obsolete intra-settlement specification part of address of biobank contact" ;
  rdfs:subClassOf <http://www.geneontology.org/formats/oboInOwl#ObsoleteClass> .

obo:OBIB_0000218 a rdfs:Class ;
  rdfs:label "in-house manufacturer" ;
  rdfs:comment "A manufacturer that produces materials internally for the internal needs of the organization." ;
  rdfs:subClassOf obo:OBI_0000835 .

obo:OBI_0000932 a rdfs:Class ;
  rdfs:label "material separation device" ;
  rdfs:comment "A device with a separation function realized in a planed process" ;
  rdfs:subClassOf obo:OBI_0000968 .

obo:OMRSE_00000050 a rdfs:Class ;
  rdfs:label "Homo sapiens role"@en ;
  rdfs:subClassOf obo:OMRSE_00000048 .

obo:OBIB_0000623 a rdfs:Class ;
  rdfs:label "biobank organization"@en ;
  rdfs:comment "An organization bearing legal personality that owns or adminstrates a biobank."@en ;
  rdfs:subClassOf obo:OBI_0000245 .

obo:RO_0000053 a rdf:Property ;
  rdfs:label "has characteristic"@en ;
  rdfs:comment "Inverse of characteristic_of"@en ;
  rdfs:range obo:BFO_0000020 .

obo:OBI_0001688 a rdf:Property ;
  rdfs:label "has organization member"@en ;
  rdfs:comment "Relating an organization to a legal person or organization." ;
  rdfs:range <https://w3id.org/linkml/Any> .

obo:UBERON_0001120 a rdfs:Class ;
  rdfs:label "left lobe of thyroid gland" ;
  rdfs:comment "A lobe of thyroid gland that is in the left side of a thyroid gland." ;
  rdfs:subClassOf obo:UBERON_0000064 .

obo:DOID_5828 a rdfs:Class .

obo:UBERON_0002409 a rdfs:Class ;
  rdfs:label "pericardial fluid" ;
  rdfs:comment "Transudate contained in the pericardial cavity.[FMA]." ;
  rdfs:subClassOf obo:UBERON_0006314 .

obo:OBIB_0000341 a rdfs:Class ;
  rdfs:label "manual FFPE tissue section H&E deparaffinization" ;
  rdfs:comment "A planned process involving the manual performance of the FFPE tissue section H&E deparaffinization protocol." ;
  rdfs:subClassOf obo:OBI_0000011 .

obo:OBIB_0000328 a rdfs:Class ;
  rdfs:label "daily microtome maintenance" ;
  rdfs:comment "A microtome maintenance frequency that indicates that microtome maintenance is performed and recorded daily." ;
  rdfs:subClassOf obo:OBIB_0000327 .

obo:NCBITaxon_10376 a rdfs:Class ;
  rdfs:label "Human gammaherpesvirus 4" ;
  rdfs:subClassOf obo:NCBITaxon_10292 .

obo:OBIB_0000130 a rdfs:Class ;
  rdfs:label "time of second clamp for specimen removal" ;
  rdfs:comment "A data item that reports the time of day when the second clamp was applied to the vasculature of an organ for specimen collection." ;
  rdfs:subClassOf obo:IAO_0000027 .

obo:APOLLO_SV_00000032 a rdfs:Class ;
  rdfs:label "count"@en ;
  rdfs:comment "A measurement datum that is the output of counting."@en ;
  rdfs:subClassOf obo:IAO_0000109 .

obo:OBI_0002519 a rdfs:Class ;
  rdfs:label "skeletal muscle tissue specimen" ;
  rdfs:comment "A specimen that is derived from skeletal muscle." ;
  rdfs:subClassOf obo:OBI_0001479 .

obo:OBIB_0000425 a rdfs:Class ;
  rdfs:label "reason for not taking a photograph of resected tissue in pathology gross room" ;
  rdfs:comment "A textual entity that describes the reason no photographs were taken of a resected tissue specimen in the pathology gross room." ;
  rdfs:subClassOf obo:IAO_0000300 .

obo:UO_0000095 a rdfs:Class ;
  rdfs:label "volume unit" ;
  rdfs:subClassOf obo:IAO_0000003 .

obo:OBIB_0000652 a rdfs:Class ;
  rdfs:label "department of sample collection or study contact"@en ;
  rdfs:comment "A department that has a contact person for a sample collection or a study as an organizational member."@en ;
  rdfs:subClassOf obo:OBIB_0000630 .

obo:OBIB_0000527 a rdfs:Class ;
  rdfs:label "time since last usage of hormonal birth control" ;
  rdfs:comment "A time measurement datum that is the result of measuring the time elapsed since the participant last used hormonally based birth control." ;
  rdfs:subClassOf obo:IAO_0000416 .

obo:OBIB_0000414 a rdfs:Class ;
  rdfs:label "specimen transport from OR to gross room SOP" ;
  rdfs:comment "A specimen transport SOP governing the transport of tissue from the operating room (OR) to the pathology gross room." ;
  rdfs:subClassOf obo:OBIB_0000071 .

obo:OBIB_0000692 a rdfs:Class ;
  rdfs:label "number of total human study participant objective"@en ;
  rdfs:comment "An objective specification that specifies the total number of individuals who are planned to participate in study."@en ;
  rdfs:subClassOf obo:IAO_0000005 .

obo:OBIB_0000388 a rdfs:Class ;
  rdfs:label "date of submission of pathology case summary report" ;
  rdfs:comment "A data item that reports the calendar date when a pathology case summary report was submitted." ;
  rdfs:subClassOf obo:IAO_0000027 .

obo:OBIB_0000299 a rdfs:Class ;
  rdfs:label "number of FFPE stages/replicates" ;
  rdfs:comment "A data item that indicates the number of stages and replicates in a FFPE process." ;
  rdfs:subClassOf obo:IAO_0000027 .

obo:OMIABIS_0001016 a rdfs:Class ;
  rdfs:label "obsolete number of total human study participant objective" ;
  rdfs:subClassOf <http://www.geneontology.org/formats/oboInOwl#ObsoleteClass> .

obo:OBI_0001506 a rdfs:Class ;
  rdfs:label "specimen with pre- or post-mortem status"@en ;
  rdfs:comment "A specimen that has been established to be taken from a live (pre-mortem) or dead (post-mortem) organism." ;
  rdfs:subClassOf obo:OBI_0100051 .

obo:OBIB_0000024 a rdfs:Class ;
  rdfs:label "collection packet with specimen"@en ;
  rdfs:comment "A collection packet which contains a container with a specimen." ;
  rdfs:subClassOf obo:OBIB_0000028 .

obo:OBI_0002556 a rdfs:Class ;
  rdfs:label "minimum age value specification"@en ;
  rdfs:comment "A value specifcation that specifies the youngest age when specifying an age range."@en ;
  rdfs:subClassOf obo:OBI_0001933 .

obo:OBIB_0000105 a rdfs:Class ;
  rdfs:label "preoperative intravenous administration of medication" ;
  rdfs:comment "A planned process to administer medication intravenously prior to surgery." ;
  rdfs:subClassOf obo:OBI_0000011 .

obo:OBI_0002422 a rdfs:Class ;
  rdfs:label "indicator of whether all inclusion criteria were met" ;
  rdfs:comment "An information content entity  that indicates whether or not  an entity  has met all specific requirements in order to take part in a given process." ;
  rdfs:subClassOf obo:IAO_0000030 .

obo:OBIB_0000724 a rdfs:Class ;
  rdfs:label "time of specimen freezing"@en ;
  rdfs:comment "A data item that reports the time when a specimen was frozen."@en ;
  rdfs:subClassOf obo:IAO_0000027 .

obo:OBI_0002743 a rdfs:Class ;
  rdfs:label "molecular label role"@en ;
  rdfs:comment "A reagent role inhering in a molecular entity intended to associate with some molecular target to serve as a proxy for the presence, abundance, or location of this target in a detection of molecular label assay."@en ;
  rdfs:subClassOf obo:OBI_0000086 .

obo:OBIB_0000080 a rdfs:Class ;
  rdfs:label "first blood draw time" ;
  rdfs:comment "A blood draw time for the first collection of a blood specimen from a donor." ;
  rdfs:subClassOf obo:OBIB_0000079 .

obo:UBERON_0001225 a rdfs:Class ;
  rdfs:label "cortex of kidney" ;
  rdfs:comment "Outer cortical portion of the kidney, between the renal capsule and the renal medulla." ;
  rdfs:subClassOf obo:UBERON_0000465 .

obo:NCBITaxon_11709 a rdfs:Class ;
  rdfs:label "Human immunodeficiency virus 2" ;
  rdfs:subClassOf obo:NCBITaxon_11646 .

obo:OBIB_0000296 a rdfs:Class ;
  rdfs:label "adherence of dehydration process temperature to FFPE tissue processing SOP" ;
  rdfs:comment "An information content entity that indicates whether temperature of the dehydration process followed that prescribed in the FFPE tissue processing SOP." ;
  rdfs:subClassOf obo:IAO_0000030 .

obo:OBIB_0000663 a rdfs:Class ;
  rdfs:label "fresh tissue specimen"@en ;
  rdfs:comment "A fresh specimen that is in a tissue form."@en ;
  rdfs:subClassOf obo:OBI_0000971 .

obo:OBI_0000747 a rdfs:Class ;
  rdfs:label "material sample" ;
  rdfs:comment "A material entity that has the material sample role" ;
  rdfs:subClassOf obo:BFO_0000040 , obo:OBI_0100051 .

obo:NCIT_C126528 a rdfs:Class ;
  rdfs:label "Central African" ;
  rdfs:comment "Denotes a person whose ancestry is in any of the countries of the central part of the African continent: Burundi, the Central African Republic, Chad, the Democratic Republic of the Congo, and Rwanda." ;
  rdfs:subClassOf obo:OBI_0000181 .

<http://vivoweb.org/ontology/core#Laboratory> a rdfs:Class ;
  rdfs:label "Laboratory" ;
  rdfs:comment "An organizational unit (as opposed to the physical facility) that performs research, provides services, or processes materials" ;
  rdfs:subClassOf obo:OBI_0000245 .

obo:UBERON_0003889 a rdfs:Class ;
  rdfs:label "fallopian tube" ;
  rdfs:comment "Initial section of the oviduct through which the ova pass from the ovary to the uterus." ;
  rdfs:subClassOf obo:UBERON_0000064 .

<http://www.ebi.ac.uk/efo/EFO_0004950> a rdfs:Class ;
  rdfs:label "date of birth" ;
  rdfs:comment "The point in time at which an individual was born." ;
  rdfs:subClassOf obo:IAO_0000416 .

obo:IAO_8000002 a rdfs:Class ;
  rdfs:label "editors ontology module"@en ;
  rdfs:comment "An ontology module that is intended to be directly edited, typically managed in source control, and typically not intended for direct consumption by end-users."@en ;
  rdfs:subClassOf obo:IAO_8000000 .

obo:IAO_8000017 a rdfs:Class ;
  rdfs:label "ontology module subsetted by expressivity"@en ;
  rdfs:subClassOf obo:IAO_8000006 .

obo:OBIB_0000132 a rdfs:Class ;
  rdfs:label "vital sign blood pressure variance early in organ excision" ;
  rdfs:comment "A data item on the duration of blood pressure variances of greater than 20 mmHg from a patient's pre-operative baseline from the time of anesthesia induction to 15 minutes post." ;
  rdfs:subClassOf obo:IAO_0000027 .

obo:OBIB_0000195 a rdfs:Class ;
  rdfs:label "reason for not banking pre-operative blood specimen" ;
  rdfs:comment "A comment from tissue procurement providing a reason that the pre-operative/pre-anesthesia blood samples were not received in a biobank as per SOP." ;
  rdfs:subClassOf obo:OBIB_0000712 .

obo:OBIB_0000116 a rdfs:Class ;
  rdfs:label "administration of medication during surgery" ;
  rdfs:comment "A planned process to administer medication(s) during a surgical procedure." ;
  rdfs:subClassOf obo:OBI_0000011 .

obo:NCIT_C77817 a rdfs:Class ;
  rdfs:label "Western European" ;
  rdfs:comment "Denotes a person having origins in any of the countries of Western Europe such as Spain, Portugal, or France." ;
  rdfs:subClassOf obo:NCIT_C43851 .

obo:UBERON_0013756 a rdfs:Class ;
  rdfs:label "venous blood" ;
  rdfs:comment "A blood that is part of a vein." ;
  rdfs:subClassOf obo:UBERON_0000178 .

obo:OBI_1110109 a rdfs:Class ;
  rdfs:label "target of material addition" ;
  rdfs:comment "A material entity that receives the addition of another material entity in an “adding a material entity into a target” process." ;
  rdfs:subClassOf obo:BFO_0000040 .

obo:OBIB_0000540 a rdfs:Class ;
  rdfs:label "estrogen with progestin hormone replacement therapy" ;
  rdfs:comment "A hormone replacement therapy where the hormones are estrogen and progestin." ;
  rdfs:subClassOf <http://www.ebi.ac.uk/efo/EFO_0003961> .

obo:OBIB_0002008 a rdfs:Class ;
  rdfs:label "research authorization for post mortem specimen donation for a specific tissue or fluid"@en ;
  rdfs:comment "A research authorization documentation for postmortem specimen donation in which the authorization is for a specified tissue or biological fluid." ;
  rdfs:subClassOf obo:OBIB_0000459 .

obo:CL_0000000 a rdfs:Class ;
  rdfs:label "cell" ;
  rdfs:comment "A material entity of anatomical origin (part of or deriving from an organism) that has as its parts a maximally connected cell compartment surrounded by a plasma membrane." ;
  rdfs:subClassOf obo:BFO_0000040 .

obo:CHEBI_3215 a rdfs:Class ;
  rdfs:label "bupivacaine" ;
  rdfs:comment "A racemate composed of equimolar amounts of dextrobupivacaine and levobupivacaine. Used (in the form of its hydrochloride hydrate) as a local anaesthetic." ;
  rdfs:subClassOf obo:CHEBI_23367 .

obo:UBERON_0002415 a rdfs:Class ;
  rdfs:label "tail" ;
  rdfs:comment "An external caudal extension of the body. In chordates, the tail is post-anal, in other animals the anus ends in the tail." ;
  rdfs:subClassOf obo:UBERON_0000465 .

obo:OBIB_0000551 a rdfs:Class ;
  rdfs:label "clinical history of cellulitis" ;
  rdfs:comment "A clinical history in which there is a history of cellulitis." ;
  rdfs:subClassOf obo:OGMS_0000015 .

obo:OBIB_0000505 a rdfs:Class ;
  rdfs:label "date of immunotherapy prior to surgery" ;
  rdfs:comment "A data item that reports the calendar date when immunotherapy was received prior to surgery." ;
  rdfs:subClassOf obo:IAO_0000027 .

obo:OBIB_0000213 a rdfs:Class ;
  rdfs:label "neutral buffered formalin" ;
  rdfs:comment "A processed material that is a mixture of formalin (formaldehyde), phosphates, and water used as a standard fixative for diagnostic preparations." ;
  rdfs:subClassOf obo:OBI_0000047 .

obo:BFO_0000027 a rdfs:Class ;
  rdfs:label "object aggregate"@en ;
  rdfs:subClassOf obo:BFO_0000040 .

obo:OBIB_0000330 a rdfs:Class ;
  rdfs:label "water bath maintenance frequency" ;
  rdfs:comment "An information content entity that indicates the frequency with which water bath maintenance is performed and recorded." ;
  rdfs:subClassOf obo:IAO_0000030 .

obo:OBIB_0000591 a rdfs:Class ;
  rdfs:label "clinical history of Hepatitis B" ;
  rdfs:comment "A clinical history in which there is a history of Hepatitis B infection." ;
  rdfs:subClassOf obo:OGMS_0000015 .

obo:OBIB_0000335 a rdfs:Class ;
  rdfs:label "FFPE tissue section H&E staining in oven duration" ;
  rdfs:comment "A time measurement datum that is the result of measuring the duration in an oven for the hematoxylin and eosin staining of a formalin-fixed paraffin-embedded (FFPE) tissue section." ;
  rdfs:subClassOf obo:IAO_0000416 .

obo:OBIB_0000464 a rdfs:Class ;
  rdfs:label "research authorization for post mortem specimen donation not obtained due to surgeon's recommendation" ;
  rdfs:comment "A research authorization documentation for post mortem specimen donation in which authorization was not obtained because the donors surgeon did not recommend it." ;
  rdfs:subClassOf obo:OBIB_0000459 .

obo:OBI_0002616 a rdfs:Class ;
  rdfs:label "genealogical record"@en ;
  rdfs:comment "A document about the family relationships of persons related as members of a domestic group linked through descent from a common ancestor, marriage, or adoption." ;
  rdfs:subClassOf obo:IAO_0000310 .

obo:CHEBI_7773 a rdfs:Class ;
  rdfs:label "Ondansetron" ;
  rdfs:subClassOf obo:CHEBI_23367 .

obo:IAO_0000100 a rdfs:Class ;
  rdfs:label "data set"@en ;
  rdfs:comment "A data item that is an aggregate of other data items of the same type that have something in common. Averages and distributions can be determined for data sets."@en ;
  rdfs:subClassOf obo:IAO_0000027 .

obo:OBIB_0000676 a rdfs:Class ;
  rdfs:label "fixation"@en ;
  rdfs:comment "A material processing that uses chemical process by which biological tissues are preserved from decay. Fixation terminates any ongoing biochemical reactions and may increase stability of the treated tissues."@en ;
  rdfs:subClassOf obo:OBI_0000094 .

obo:OBIB_0000229 a rdfs:Class ;
  rdfs:label "date and time of blood collection" ;
  rdfs:comment "A data item indicating the date and time when a blood specimen was collected." ;
  rdfs:subClassOf obo:IAO_0000027 .

obo:OBIB_0000494 a rdfs:Class ;
  rdfs:label "limitations on research authorization for use of donated specimens" ;
  rdfs:comment "An authorization documentation for postmortem specimen donation in which authorization includes specific limitations or additional information related to the use of tissue for research." ;
  rdfs:subClassOf obo:OBIB_0000490 .

obo:OBIB_0000122 a rdfs:Class ;
  rdfs:label "subtotal colectomy" ;
  rdfs:comment "A colectomy that is complete resection of the colon" ;
  rdfs:subClassOf obo:OAE_0001159 .

obo:OMIABIS_0001054 a rdfs:Class ;
  rdfs:label "obsolete normal specimen" ;
  rdfs:subClassOf <http://www.geneontology.org/formats/oboInOwl#ObsoleteClass> .

obo:GEO_000000396 a rdfs:Class ;
  rdfs:label "sovereign state"@en ;
  rdfs:comment "A governmental organization with a defined territory on which it exercises internal and external sovereignty, a permanent population, a government, and the capacity to enter into relations with other sovereign states."@en ;
  rdfs:subClassOf obo:GEO_000000400 .

obo:OBIB_0000057 a rdfs:Class ;
  rdfs:label "tobacco material"@en ;
  rdfs:comment "A processed material that is made from tobacco. Typically, tobacco material is meant to be used as a source of nicotine as tobacco contains a higher concentration of nicotine than most other plants." ;
  rdfs:subClassOf obo:OBI_0000047 .

obo:UBERON_0000992 a rdfs:Class ;
  rdfs:label "ovary" ;
  rdfs:comment "The gonad of a female organism which contains germ cells." ;
  rdfs:subClassOf obo:UBERON_0000465 .

obo:HANCESTRO_0019 a rdfs:Class ;
  rdfs:label "Japanese" ;
  rdfs:subClassOf obo:HANCESTRO_0008 .

obo:OBI_0002504 a rdfs:Class ;
  rdfs:label "digestive system fluid or secretion specimen" ;
  rdfs:comment "A specimen that is derived from digestive system fluid or secretion." ;
  rdfs:subClassOf obo:OBI_0001479 .

obo:OBIB_0000731 a rdfs:Class ;
  rdfs:label "end of sampling specimens for biobank"@en ;
  rdfs:comment "The process boundary marking the end of a sampling of specimens into a biobank."@en ;
  rdfs:subClassOf obo:BFO_0000035 .

obo:OBIB_0000375 a rdfs:Class ;
  rdfs:label "date and time FFPE tissue cassette was frozen" ;
  rdfs:comment "A data item indicating the date and time when a tissue cassette was frozen as part of a formalin-fixed paraffin-embedded (FFPE) process." ;
  rdfs:subClassOf obo:IAO_0000027 .

obo:OMIABIS_0000099 a rdfs:Class ;
  rdfs:label "obsolete sample collection or study contact person" ;
  rdfs:subClassOf <http://www.geneontology.org/formats/oboInOwl#ObsoleteClass> .

obo:OBIB_0000502 a rdfs:Class ;
  rdfs:label "time since hormonal therapy was received prior to surgery" ;
  rdfs:comment "A time measurement datum that is the result of measuring the time elapsed since hormonal therapy prior to surgery." ;
  rdfs:subClassOf obo:IAO_0000416 .

obo:OBIB_0000475 a rdfs:Class ;
  rdfs:label "date that research authorization for post mortem specimen donation was witnessed" ;
  rdfs:comment "A data item that indicates the calendar date on which the signing  of the research authorization for post mortem specimen donation by the legally authorized individual was witnessed." ;
  rdfs:subClassOf obo:IAO_0000027 .

obo:OBI_0001164 a rdfs:Class ;
  rdfs:label "age since sowing measurement datum"@en ;
  rdfs:comment "An age measurement datum that is the result of the measurement of the age of an organism since sowing, the process of placing a seed or spore in some media with the intention to invoke germination." ;
  rdfs:subClassOf obo:OBI_0001167 .

obo:OBI_0001003 a rdfs:Class ;
  rdfs:label "agar stab storage" ;
  rdfs:comment "a storage process with input cell culture and agar and output agar stab for long time storage" ;
  rdfs:subClassOf obo:OBI_0302893 .

obo:IAO_0000572 a rdfs:Class ;
  rdfs:label "documenting"@en ;
  rdfs:comment "A planned process in which a document is created or added to by including the specified input in it."@en ;
  rdfs:subClassOf obo:OBI_0000011 .

obo:OMIABIS_0000054 a rdfs:Class ;
  rdfs:label "obsolete fresh tissue specimen" ;
  rdfs:subClassOf <http://www.geneontology.org/formats/oboInOwl#ObsoleteClass> .

obo:OBI_0001879 a rdfs:Class ;
  rdfs:label "reagent"@en ;
  rdfs:comment "A biological or chemical entity that bears a reagent role in virtue of it being intended for application in a scientific technique  to participate in (or have molecular parts that participate in) a chemical reaction that facilitates the generation of data about some distinct entity, or the generation of some distinct material specified output." ;
  rdfs:subClassOf obo:BFO_0000040 , obo:OBI_0000047 .

obo:OMIABIS_0001039 a rdfs:Class ;
  rdfs:label "obsolete date of specimen collection" ;
  rdfs:subClassOf <http://www.geneontology.org/formats/oboInOwl#ObsoleteClass> .

obo:BFO_0000023 a rdfs:Class ;
  rdfs:label "role"@en ;
  rdfs:comment "A realizable entity  the manifestation of which brings about some result or end that is not essential to a continuant  in virtue of the kind of thing that it is but that can be served or participated in by that kind of continuant  in some kinds of natural, social or institutional contexts."@en ;
  rdfs:subClassOf obo:BFO_0000017 .

obo:OBIB_0000152 a rdfs:Class ;
  rdfs:label "comment on notable events during donor surgery" ;
  rdfs:comment "A comment from tissue procurement of notable events that occurred during surgery." ;
  rdfs:subClassOf obo:OBIB_0000712 .

obo:OBIB_0000346 a rdfs:Class ;
  rdfs:label "H&E staining equipment maintenance performed and recorded frequency" ;
  rdfs:comment "A data item that indicates the frequency with which hematoxylin and eosin (H&E) staining equipment maintenance is performed and recorded." ;
  rdfs:subClassOf obo:IAO_0000027 .

obo:OBIB_0000363 a rdfs:Class ;
  rdfs:label "FFPE fixation protocol" ;
  rdfs:comment "A protocol for the fixation step of a formalin-fixed paraffin-embedded (FFPE) process." ;
  rdfs:subClassOf obo:OBI_0000272 .

obo:OBIB_0000306 a rdfs:Class ;
  rdfs:label "adherence of paraffin temperature to FFPE tissue processing SOP" ;
  rdfs:comment "An information content entity that indicates whether the paraffin temperature followed that prescribed in the FFPE tissue processing SOP." ;
  rdfs:subClassOf obo:IAO_0000030 .

obo:OBIB_0000224 a rdfs:Class ;
  rdfs:label "approval to proceed with collection" ;
  rdfs:comment "An information content entity indicating whether approval was received to proceed with collection." ;
  rdfs:subClassOf obo:IAO_0000030 .

obo:CHEBI_16236 a rdfs:Class ;
  rdfs:label "ethanol" ;
  rdfs:comment "A primary alcohol that is ethane in which one of the hydrogens is substituted by a hydroxy group." ;
  rdfs:subClassOf obo:CHEBI_30879 .

obo:OBIB_0000386 a rdfs:Class ;
  rdfs:label "comment on FFPE slide image" ;
  rdfs:comment "A textual entity that states information relevant to an image from a formalin-fixed paraffin-embedded (FFPE) slide." ;
  rdfs:subClassOf obo:IAO_0000300 .

obo:UBERON_0010414 a rdfs:Class ;
  rdfs:label "omental fat pad" ;
  rdfs:comment "Encapsulated adipose tissue associated with the fold of peritoneal tissue that extends from the stomach to the posterior abdominal wall after associating with the transverse colon." ;
  rdfs:subClassOf obo:UBERON_0001013 .

obo:OBIB_0000046 a rdfs:Class ;
  rdfs:label "cigar"@en ;
  rdfs:comment "A processed material which is a tightly-rolled bundle of dried and fermented tobacco that is ignited so that its smoke may be drawn into the mouth." ;
  rdfs:subClassOf obo:OBIB_0000048 , obo:OBIB_0000057 .

obo:OBIB_0000516 a rdfs:Class ;
  rdfs:label "timing of scoring performance status" ;
  rdfs:comment "A one-dimensional temporal region during which a cancer patient's performance status (general well-being and activities of daily life) was assessed." ;
  rdfs:subClassOf obo:BFO_0000038 .

obo:OBI_0600014 a rdfs:Class ;
  rdfs:label "material component separation"@en ;
  rdfs:comment "a material processing in which components of an input material become segregated in space"@en ;
  rdfs:subClassOf obo:OBI_0000094 .

obo:OBIB_0000404 a rdfs:Class ;
  rdfs:label "FFPE slide findings that do not meet microscopic analysis criteria" ;
  rdfs:comment "A textual entity that describes findings upon review of a formalin-fixed paraffin-embedded (FFPE) slide that do not meet microscopic analysis criteria." ;
  rdfs:subClassOf obo:IAO_0000300 .

obo:OBI_0000471 a rdfs:Class ;
  rdfs:label "study design execution" ;
  rdfs:comment "a planned process that carries out a study design" ;
  rdfs:subClassOf obo:OBI_0000011 .

obo:FMA_22110 a rdfs:Class ;
  rdfs:label "Left tibial nerve" ;
  rdfs:subClassOf obo:UBERON_0001323 .

obo:OBIB_0000171 a rdfs:Class ;
  rdfs:label "robotic surgical method" ;
  rdfs:comment "A surgical method using very small tools attached to a robotic arm. The surgeon controls the robotic arm with a computer." ;
  rdfs:subClassOf obo:OBIB_0000165 .

obo:GO_0008150 a rdfs:Class ;
  rdfs:label "biological_process" ;
  rdfs:comment "A biological process is the execution of a genetically-encoded biological module or program. It consists of all the steps required to achieve the specific biological objective of the module. A biological process is accomplished by a particular set of molecular functions carried out by specific gene products (or macromolecular complexes), often in a highly regulated manner and in a particular temporal sequence." ;
  rdfs:subClassOf obo:BFO_0000015 .

obo:OMIABIS_0001032 a rdfs:Class ;
  rdfs:label "obsolete study subject survey data" ;
  rdfs:subClassOf <http://www.geneontology.org/formats/oboInOwl#ObsoleteClass> .

obo:OMIABIS_0000035 a rdfs:Class ;
  rdfs:label "obsolete email address of sample collection or study contact" ;
  rdfs:subClassOf <http://www.geneontology.org/formats/oboInOwl#ObsoleteClass> .

obo:OMRSE_00000209 a rdfs:Class ;
  rdfs:label "gender identity information content entity"@en ;
  rdfs:comment "A social identity information content entity that is about whether some person identifies as some gender."@en ;
  rdfs:subClassOf obo:OMRSE_00000204 .

obo:OBI_0000838 a rdfs:Class ;
  rdfs:label "material maintenance" ;
  rdfs:comment "a process with that achieves the objective to maintain some or all of the characteristics of an input material over time" ;
  rdfs:subClassOf obo:OBI_0000011 .

obo:OBIB_0000099 a rdfs:Class ;
  rdfs:label "non-performance of an assay" ;
  rdfs:comment "An information content entity that is about the status of an assay and indicates that the assay has not been started or completed." ;
  rdfs:subClassOf obo:IAO_0000030 .

obo:OBIB_0000397 a rdfs:Class ;
  rdfs:label "percentage of viable tumor slide specimen by surface area" ;
  rdfs:comment "A data item that is the result of determining the percentage of a tumor slide specimen that is viable based on surface area not including stroma." ;
  rdfs:subClassOf obo:IAO_0000027 .

obo:OBIB_0000458 a rdfs:Class ;
  rdfs:label "research authorization obtainer role for post mortem donation of specimens from a legally authorized representative" ;
  rdfs:comment "A role borne by a person who approaches a person's legal representative and informs them of key facts about potential risks and benefits, and asks them for authorization for post-mortem specimen donation  for general research for the person they legally represent." ;
  rdfs:subClassOf obo:BFO_0000023 .

obo:OBI_0002455 a rdfs:Class ;
  rdfs:label "clinically relevant exposure inclusion criterion"@en ;
  rdfs:comment "An inclusion criterion that defines and states one or more clinically relevant histories of exposure of an entity, which, if met, makes the entity suitable for a given task or participation in a given process."@en ;
  rdfs:subClassOf obo:OBI_0500027 .

obo:OBI_0001163 a rdfs:Class ;
  rdfs:label "age since eclosion measurement datum"@en ;
  rdfs:comment "An age measurement datum that is the result of the measurement of the age of an organism since eclosion, the process of emergence of an adult insect from its pupa or cocoon." ;
  rdfs:subClassOf obo:OBI_0001167 .

obo:OBIB_0000453 a rdfs:Class ;
  rdfs:label "activity related to a particular specimen donor was stopped because not enough tissue" ;
  rdfs:comment "An activity related to a particular specimen donor was stopped that is because there was not enough tissue." ;
  rdfs:subClassOf obo:OBIB_0000451 .

obo:OBI_0001034 a rdfs:Class ;
  rdfs:label "environmental control device" ;
  rdfs:comment "An environmental control device is a device which has the function to control some aspect of the environment such as temperature, or humidity." ;
  rdfs:subClassOf obo:OBI_0000968 .

obo:OBI_0000977 a rdfs:Class ;
  rdfs:label "paraffin storage" ;
  rdfs:comment "a storage process with input organism or anatomical entity and paraffin and output material embedded in paraffin for long term storage" ;
  rdfs:subClassOf obo:OBI_0302893 .

obo:PATO_0001422 a rdfs:Class ;
  rdfs:label "dead" ;
  rdfs:comment "A viability quality inhering in a bearer by virtue of the cessation of the bearer's life." ;
  rdfs:subClassOf obo:PATO_0000169 .

obo:OBIB_0000317 a rdfs:Class ;
  rdfs:label "comment on paraffin embedding of FFPE tissue" ;
  rdfs:comment "A textual entity that states information relevant to paraffin embedding of a formalin-fixed paraffin-embedded (FFPE) tissue." ;
  rdfs:subClassOf obo:IAO_0000300 .

obo:OBI_0002561 a rdfs:Class ;
  rdfs:label "sex inclusion criterion"@en ;
  rdfs:comment "An inclusion criterion that defines and states one or more sexes which, if met, makes an entity suitable for a given task or participation in a given process."@en ;
  rdfs:subClassOf obo:OBI_0500027 .

obo:OBIB_0000500 a rdfs:Class ;
  rdfs:label "time since chemotherapy was received prior to surgery" ;
  rdfs:comment "A time measurement datum that is the result of measuring the time elapsed since chemotherapy prior to surgery." ;
  rdfs:subClassOf obo:IAO_0000416 .

obo:OBIB_0000377 a rdfs:Class ;
  rdfs:label "FFPE freezing by dry ice protocol" ;
  rdfs:comment "A FFPE freezing protocol that involves the use of dry ice." ;
  rdfs:subClassOf obo:OBI_0000272 .

obo:OMRSE_00000038 a rdfs:Class ;
  rdfs:label "legal person role"@en ;
  rdfs:comment "A role borne by a human individual or by a collection of humans regarded as possessing rights and duties enforeable at law."@en ;
  rdfs:subClassOf obo:OMRSE_00002072 .

obo:OBI_0000383 a rdfs:Class ;
  rdfs:label "transfer function"@en ;
  rdfs:comment "A transfer function is a function to displace a material from one location to another."@en ;
  rdfs:subClassOf obo:BFO_0000034 .

obo:OBI_0002201 a rdfs:Class ;
  rdfs:label "determination if assay will provide reliable results" ;
  rdfs:comment "A planned process that is used to assess whether an assay will provide reliable results based on the conditions or qualities of the inputs, devices, and other participants of the assay." ;
  rdfs:subClassOf obo:OBI_0000011 .

obo:NCBITaxon_11646 a rdfs:Class ;
  rdfs:label "Lentivirus" ;
  rdfs:subClassOf obo:NCBITaxon_10239 .

obo:OBIB_0000357 a rdfs:Class ;
  rdfs:label "laboratory, data analysis, and coordinating center for human specimens" ;
  rdfs:comment "A laboratory that specializes in acquiring human tissues and analyzing components such as DNA and RNA from them." ;
  rdfs:subClassOf <http://vivoweb.org/ontology/core#Laboratory> .

obo:OBIB_0000704 a rdfs:Class ;
  rdfs:label "sample handling summary"@en ;
  rdfs:comment "A document that outlines the procedures employed to preserve and protect the material collected during specimen collection as an indication of sample quality."@en ;
  rdfs:subClassOf obo:IAO_0000310 .

obo:OBIB_0000184 a rdfs:Class ;
  rdfs:label "left lung biopsy" ;
  rdfs:comment "A biopsy of the left lung." ;
  rdfs:subClassOf obo:OBI_0002650 .

obo:OBI_0002416 a rdfs:Class ;
  rdfs:label "exposure to arsenic history" ;
  rdfs:comment "An exposure to environmental and workplace carcinogens history where the carcinogen is arsenic." ;
  rdfs:subClassOf obo:OBI_0002415 .

obo:NCIT_C41263 a rdfs:Class ;
  rdfs:label "South Asian" ;
  rdfs:comment "Denotes a person whose ancestry is in the countries of the Indian sub-continent, including India, Pakistan, Bangladesh, and Sri Lanka." ;
  rdfs:subClassOf obo:OBI_0000181 .

obo:OBI_0000651 a rdfs:Class ;
  rdfs:label "urine specimen" ;
  rdfs:comment "a portion of urine collected from an organism" ;
  rdfs:subClassOf obo:OBI_0001479 .

obo:IAO_8000013 a rdfs:Class ;
  rdfs:label "reasoned ontology module"@en ;
  rdfs:comment "An ontology module that contains axioms generated by a reasoner. The generated axioms are typically direct SubClassOf axioms, but other possibilities are available."@en ;
  rdfs:seeAlso <http://robot.obolibrary.org/reason> ;
  rdfs:subClassOf obo:IAO_8000000 .

obo:CHEBI_6456 a rdfs:Class ;
  rdfs:label "lidocaine" ;
  rdfs:comment "The monocarboxylic acid amide resulting from the formal condensation of N,N-diethylglycine with 2,6-dimethylaniline." ;
  rdfs:subClassOf obo:CHEBI_23367 .

obo:OBIB_0000612 a rdfs:Class ;
  rdfs:label "indication of body piercing from non-professional" ;
  rdfs:comment "An information content entity in which there is an indication of whether an individual has signs of non-professional  body piercing." ;
  rdfs:subClassOf obo:IAO_0000030 .

obo:OBIB_0000418 a rdfs:Class ;
  rdfs:label "humidity in gross room when specimen arrived from OR" ;
  rdfs:comment "A measurement datum that is the output of an assay of humidity occurring in a pathology gross room and performed when a specimen arrived from the operating room (OR)." ;
  rdfs:subClassOf obo:IAO_0000109 .

obo:OBIB_0000235 a rdfs:Class ;
  rdfs:label "PAXgene RNA vacutainer" ;
  rdfs:comment "A specimen container developed by PreAnalytiX that contains a proprietary reagent for stabilization of intracellular RNA immediately upon collection." ;
  rdfs:subClassOf obo:OBI_0002088 .

obo:OMIABIS_0001021 a rdfs:Class ;
  rdfs:label "obsolete panel study design" ;
  rdfs:subClassOf <http://www.geneontology.org/formats/oboInOwl#ObsoleteClass> .

obo:OBIB_0000580 a rdfs:Class ;
  rdfs:label "clinical history of a prolonged fever" ;
  rdfs:comment "A clinical history in which there is a history of  fever of at least 38.6 Celsius for a specified duration." ;
  rdfs:subClassOf obo:OGMS_0000015 .

obo:OBI_0001051 a rdfs:Class ;
  rdfs:label "DNA extract" ;
  rdfs:comment "The output of an extraction process in which DNA molecules are purified in order to exclude DNA from organellas." ;
  rdfs:subClassOf obo:OBI_0001010 .

obo:OBI_0002608 a rdfs:Class ;
  rdfs:label "oropharyngeal swab specimen" ;
  rdfs:comment "A specimen that is collected with a swab from the surface of a oropharynx." ;
  rdfs:subClassOf obo:OBI_0002599 .

obo:OBIB_0000670 a rdfs:Class ;
  rdfs:label "sample collection or study contact role"@en ;
  rdfs:comment "A contact role borne by a member of a sample collection or study organization and realized by serving as the contact for the collection or the study."@en ;
  rdfs:subClassOf obo:OBIB_0000625 .

obo:OBI_0000401 a rdfs:Class ;
  rdfs:label "environment control function"@en ;
  rdfs:comment "An environmental control function is a function that regulates a contained environment within specified parameter ranges. For example the control of light exposure, humidity and temperature."@en ;
  rdfs:subClassOf obo:BFO_0000034 .

obo:OBIB_0000154 a rdfs:Class ;
  rdfs:label "hysterectomy with bilateral salpingo-oophorectomy" ;
  rdfs:comment "A surgical procedure with the removal of the uterus, cervix, fallopian tubes, and ovaries. This is the most common surgery done for endometrial cancer." ;
  rdfs:subClassOf obo:OBIB_0000716 .

obo:OBIB_0000469 a rdfs:Class ;
  rdfs:label "research authorization for post mortem specimen donation not obtained because legally authorized representative was afraid the decision might affect the surgery plans of donor" ;
  rdfs:comment "A research authorization documentation for post mortem specimen donation in which authorization was not obtained because the the legally authorized representative was afraid the decision might affect the surgery plans for the donor." ;
  rdfs:subClassOf obo:OBIB_0000459 .

obo:OBIB_0000201 a rdfs:Class ;
  rdfs:label "data and time of biobank receipt of specimen" ;
  rdfs:comment "A data item indicating the date and time at which the specimen was received in the biobank." ;
  rdfs:subClassOf obo:IAO_0000027 .

obo:OBIB_0000203 a rdfs:Class ;
  rdfs:label "comment from specimen receipt" ;
  rdfs:comment "A textual entity that states a comment or issue regarding specimen receipt or deviations from a standard operating procedure for specimen receipt." ;
  rdfs:subClassOf obo:IAO_0000300 .

obo:BFO_0000016 a rdfs:Class ;
  rdfs:label "disposition"@en ;
  rdfs:subClassOf obo:BFO_0000017 .

obo:OBIB_0000486 a rdfs:Class ;
  rdfs:label "indicator of whether specimen donor has reached the age of majority" ;
  rdfs:comment "An Information content entity that indicates whether the specimen donor  has reached the age of majority as defined by the appropriate regulation." ;
  rdfs:subClassOf obo:IAO_0000030 .

obo:OMIABIS_00001010 a rdfs:Class ;
  rdfs:label "obsolete diseased state specimen datum" ;
  rdfs:subClassOf <http://www.geneontology.org/formats/oboInOwl#ObsoleteClass> .

obo:HANCESTRO_0008 a rdfs:Class ;
  rdfs:label "Asian" ;
  rdfs:comment "Includes individuals that either self-report or have been described as Asian but there was not sufficient information to allow classification as East Asian, Central Asian, South Asian or South-East Asian."@en ;
  rdfs:subClassOf obo:HANCESTRO_0004 .

obo:OBIB_0000429 a rdfs:Class ;
  rdfs:label "explanation of why tumor tissue specimen was not released to a biobank" ;
  rdfs:comment "A textual entity that describes the reason why a tumor tissue specimen was not released to a biobank." ;
  rdfs:subClassOf obo:IAO_0000300 .

obo:OBI_0100067 a rdfs:Class ;
  rdfs:label "bronchial alveolar lavage"@en ;
  rdfs:comment "Group of biomaterials present in the bronchial aveolar space of an organism which are collected through lavage including the reagents used to for the lavage process, organisms, cells, and cellular secretions present in the bronchial aveolar space."@en ;
  rdfs:subClassOf obo:OBI_0000953 .

obo:UBERON_0007650 a rdfs:Class ;
  rdfs:label "esophagogastric junction" ;
  rdfs:comment "The junction between the esophagus and the stomach epithelium." ;
  rdfs:subClassOf obo:UBERON_0000064 .

obo:OBIB_0000173 a rdfs:Class ;
  rdfs:label "left kidney biopsy" ;
  rdfs:comment "A biopsy of the left kidney." ;
  rdfs:subClassOf obo:OBI_0002650 .

obo:OBI_0002515 a rdfs:Class ;
  rdfs:label "pleural fluid specimen" ;
  rdfs:comment "A specimen that is derived from pleural fluid." ;
  rdfs:subClassOf obo:OBI_2000009 .

obo:UBERON_0000165 a rdfs:Class ;
  rdfs:label "mouth" ;
  rdfs:comment "The proximal portion of the digestive tract, containing the oral cavity and bounded by the oral opening. In vertebrates, this extends to the pharynx and includes gums, lips, tongue and parts of the palate. Typically also includes the teeth, except where these occur elsewhere (e.g. pharyngeal jaws) or protrude from the mouth (tusks)." ;
  rdfs:subClassOf obo:UBERON_0000465 .

obo:IAO_0000030 a rdfs:Class ;
  rdfs:label "information content entity"@en ;
  rdfs:comment "A generically dependent continuant that is about some thing."@en ;
  rdfs:subClassOf obo:BFO_0000031 .

obo:CHEBI_44915 a rdfs:Class ;
  rdfs:label "propofol" ;
  rdfs:comment "A phenol resulting from the formal substitution of the hydrogen at the 2 position of 1,3-diisopropylbenzene by a hydroxy group." ;
  rdfs:subClassOf obo:CHEBI_23367 .

obo:OBIB_0000141 a rdfs:Class ;
  rdfs:label "amount of fresh frozen plasma administered intraoperatively" ;
  rdfs:comment "A count of the number of units of fresh frozen plasma administered during surgery." ;
  rdfs:subClassOf obo:APOLLO_SV_00000032 .

obo:OBI_0000370 a rdfs:Class ;
  rdfs:label "contain function"@en ;
  rdfs:comment "A contain function is a function to constrain a material entities location in space"@en ;
  rdfs:subClassOf obo:BFO_0000034 .

obo:UBERON_0001090 a rdfs:Class ;
  rdfs:label "synovial fluid" ;
  rdfs:comment "Joint fluid is a transudate of plasma that is actively secreted by synovial cells." ;
  rdfs:subClassOf obo:UBERON_0006314 .

obo:OBIB_0000719 a rdfs:Class ;
  rdfs:label "specimen surgical removal"@en ;
  rdfs:comment "A collecting specimen from organism process that involves removing the specimen from an individual through a surgical procedure."@en ;
  rdfs:subClassOf obo:OBI_0600005 .

obo:OBIB_0000127 a rdfs:Class ;
  rdfs:label "proctocolectomy" ;
  rdfs:comment "A colectomy that is the surgical removal of the rectum and all or part of the colon.[" ;
  rdfs:subClassOf obo:OAE_0001159 .

obo:OBI_0002095 a rdfs:Class ;
  rdfs:label "specimen family creation"@en ;
  rdfs:comment "A material processing that has as its input a specimen and as its output a collection of specimens."@en ;
  rdfs:subClassOf obo:OBI_0000094 .

obo:OBI_0002652 a rdfs:Class ;
  rdfs:label "computed tomography assisted biopsy" ;
  rdfs:comment "A needle biopsy guided by real-time computed tomography (CT) scan images." ;
  rdfs:subClassOf obo:OBI_0002651 .

obo:OBIB_0000498 a rdfs:Class ;
  rdfs:label "tissue collection timing and placed in fixative inclusion criterion" ;
  rdfs:comment "An inclusion criterion that is defined by whether it is likely that tissue collection can be started AND the first tissue can be placed in fixative within a specified period of time from cardiac cessation or recorded time of death (observed or presumed) for a specimen donor, which if met, makes a specimen donor suitable for a given task or participation in a given process." ;
  rdfs:subClassOf obo:OBI_0500027 .

obo:OBIB_0000447 a rdfs:Class ;
  rdfs:label "local pathology review was consistent with site of tissue procurement diagnostic pathology report" ;
  rdfs:comment "An information content entity that is an indicator of whether the local pathology review was consistent with the findings of the diagnostic pathology report from the site of specimen collection from a donor." ;
  rdfs:subClassOf obo:IAO_0000030 .

obo:OBIB_0000017 a rdfs:Class ;
  rdfs:label "data confirm questionnaire"@en ;
  rdfs:comment "A questionnaire that comprises a set of questions about patient, such as height, weight, race, biological sex, clinical history, etc., which will be filled by a recruiter based on an Electronic Medical Record (EMR)." ;
  rdfs:subClassOf obo:OBI_0001000 .

obo:OBI_0000852 a rdfs:Class ;
  rdfs:label "record of missing knowledge" ;
  rdfs:comment "An information content entity created to indicate that information about something is not available to the person recording it." ;
  rdfs:subClassOf obo:IAO_0000030 .

obo:OBI_0002534 a rdfs:Class ;
  rdfs:label "lung specimen" ;
  rdfs:comment "A specimen that is derived from lung." ;
  rdfs:subClassOf obo:OBI_0001479 .

obo:OBIB_0000726 a rdfs:Class ;
  rdfs:label "normal specimen"@en ;
  rdfs:comment "A specimen that is normal."@en ;
  rdfs:subClassOf obo:OBI_0100051 .

obo:OBIB_0000409 a rdfs:Class ;
  rdfs:label "date of FFPE slide review by the pathologist" ;
  rdfs:comment "A data item that reports the calendar date when a formalin-fixed paraffin-embedded (FFPE) slide was reviewed by a pathologist." ;
  rdfs:subClassOf obo:IAO_0000027 .

obo:OBI_0002612 a rdfs:Class ;
  rdfs:label "fecal swab specimen" ;
  rdfs:comment "A specimen that is collected with a swab from the surface of a feces." ;
  rdfs:subClassOf obo:OBI_0002599 .

obo:UBERON_0000064 a rdfs:Class ;
  rdfs:label "organ part" ;
  rdfs:comment "A multicellular structure that is a part of an organ." ;
  rdfs:subClassOf obo:UBERON_0000465 .

obo:UBERON_0035944 a rdfs:Class ;
  rdfs:label "life-death temporal boundary" ;
  rdfs:comment "A life cycle temporal boundary that marks the end of the life cycle of the organism." ;
  rdfs:subClassOf obo:BFO_0000035 .

obo:PATO_0001995 a rdfs:Class ;
  rdfs:label "organismal quality" ;
  rdfs:comment "A quality that inheres in an entire organism or part of an organism." ;
  rdfs:subClassOf obo:PATO_0001241 .

obo:OBI_0000740 a rdfs:Class ;
  rdfs:label "material sample role" ;
  rdfs:comment "A material sample role is a specimen role borne by a material entity that is the output of a material sampling process." ;
  rdfs:subClassOf obo:OBI_0000112 .

obo:OBI_0002453 a rdfs:Class ;
  rdfs:label "health status inclusion criterion"@en ;
  rdfs:comment "An inclusion criterion that defines and states one or more clinically significant bodily components, dispositions, and/or bodily processes of an entity that are inferred from relevant clinical findings or self-reported, which, if met, makes the entity suitable for a given task or participation in a given process."@en ;
  rdfs:subClassOf obo:OBI_0500027 .

obo:PATO_0000122 a rdfs:Class ;
  rdfs:label "length" ;
  rdfs:comment "A 1-D extent quality which is equal to the distance between two points." ;
  rdfs:subClassOf obo:PATO_0001708 .

obo:OBIB_0000687 a rdfs:Class ;
  rdfs:label "count of current total human study participant"@en ;
  rdfs:comment "A count that is about the aggregate of individuals who have been recruited to participate in a study."@en ;
  rdfs:subClassOf obo:APOLLO_SV_00000032 .

obo:OBI_0001912 a rdfs:Class ;
  rdfs:label "cell freezing medium"@en ;
  rdfs:comment "A processed material that serves as a liquid vehicle for freezing cells for long term quiescent stroage, which contains chemicls needed to sustain cell viability across freeze-thaw cycles." ;
  rdfs:subClassOf obo:OBI_0000047 .

obo:OMIABIS_00001013 a rdfs:Class ;
  rdfs:label "obsolete unknown state specimen data" ;
  rdfs:subClassOf <http://www.geneontology.org/formats/oboInOwl#ObsoleteClass> .

obo:OBI_0000103 a rdfs:Class ;
  rdfs:label "principal investigator role"@en ;
  rdfs:comment "a responsible party role played by a person responsible for the overall conduct of a study"@en ;
  rdfs:subClassOf obo:OBI_0000102 .

obo:OMIABIS_0001043 a rdfs:Class ;
  rdfs:label "obsolete time in formalin measurement" ;
  rdfs:subClassOf <http://www.geneontology.org/formats/oboInOwl#ObsoleteClass> .

obo:OBIB_0000255 a rdfs:Class ;
  rdfs:label "cryovial specimen barcode" ;
  rdfs:comment "A specimen barcode that is associated with a cryovial." ;
  rdfs:subClassOf obo:FLU_0001019 .

obo:OBI_0000941 a rdfs:Class ;
  rdfs:label "service consumer role" ;
  rdfs:comment "a role which inheres in a person who uses a service" ;
  rdfs:subClassOf obo:OMRSE_00000048 .

obo:NCBITaxon_7742 a rdfs:Class ;
  rdfs:label "Vertebrata <vertebrates>" ;
  rdfs:subClassOf obo:NCBITaxon_33213 .

obo:OBIB_0000070 a rdfs:Class ;
  rdfs:label "standard operating procedure" ;
  rdfs:comment "A protocol that is a set of step-by-step instructions compiled by an organization for carrying out routine operations." ;
  rdfs:subClassOf obo:OBI_0000272 .

obo:OBIB_0000371 a rdfs:Class ;
  rdfs:label "time in FFPE fixative measurement" ;
  rdfs:comment "A time in fixative measurement that states the duration during which a specimen was submerged in fixative as part of a formalin-fixed paraffin-embedded (FFPE) process." ;
  rdfs:subClassOf obo:OBIB_0000060 .

obo:ENVO_00010483 a rdfs:Class ;
  rdfs:label "environmental material" ;
  rdfs:comment "A portion of environmental material is a fiat object part which forms the medium or part of the medium of an environmental system." ;
  rdfs:subClassOf obo:BFO_0000040 .

obo:OBIB_0000266 a rdfs:Class ;
  rdfs:label "name of person processing blood cell pellet specimen" ;
  rdfs:comment "A personal name that designates the person who performed processing of the blood cell pellet specimen." ;
  rdfs:subClassOf obo:IAO_0020015 .

obo:NCIT_C45514 a rdfs:Class ;
  rdfs:label "Lung Signet Ring Cell Carcinoma" ;
  rdfs:comment "A morphologic variant of lung adenocarcinoma characterized by the presence of signet ring cells." ;
  rdfs:subClassOf obo:DOID_3910 .

obo:OBIB_0000302 a rdfs:Class ;
  rdfs:label "adherence of temperature of clearing agent to FFPE tissue processing SOP" ;
  rdfs:comment "An information content entity that indicates whether the temperature of clearing agent followed that prescribed in the FFPE tissue processing SOP." ;
  rdfs:subClassOf obo:IAO_0000030 .

obo:OMIABIS_0001075 a rdfs:Class ;
  rdfs:label "obsolete cerebrospinal fluid specimen" ;
  rdfs:subClassOf <http://www.geneontology.org/formats/oboInOwl#ObsoleteClass> .

obo:OBI_0002508 a rdfs:Class ;
  rdfs:label "sputum specimen" ;
  rdfs:comment "A specimen that is derived from sputum." ;
  rdfs:subClassOf obo:OBI_0001479 .

obo:UBERON_0001268 a rdfs:Class ;
  rdfs:label "peritoneal fluid" ;
  rdfs:comment "Transudate contained in the peritoneal cavity." ;
  rdfs:subClassOf obo:UBERON_0006314 .

obo:OBI_0002433 a rdfs:Class ;
  rdfs:label "history of sex with someone with a history of intravenous drugs exclusion criterion" ;
  rdfs:comment "An exclusion criterion defined  as whether an individual has a history of sex with someone who has used intravenous drugs in a specified time frame, which if met, makes the individual unsuitable for a given task or participation in a given process." ;
  rdfs:subClassOf obo:OBI_0500028 .

obo:OBIB_0000559 a rdfs:Class ;
  rdfs:label "clinical history of cancer within a time period before death" ;
  rdfs:comment "A clinical history in which there is a history of cancer diagnosis within a specified time frame." ;
  rdfs:subClassOf obo:OGMS_0000015 .

obo:IAO_8000006 a rdfs:Class ;
  rdfs:label "subset ontology module"@en ;
  rdfs:comment "An ontology module that is extracted from a main ontology module and includes only a subset of entities or axioms."@en ;
  rdfs:seeAlso <http://robot.obolibrary.org/filter> , <http://www.geneontology.org/page/go-slim-and-subset-guide> ;
  rdfs:subClassOf obo:IAO_8000000 .

obo:UBERON_0000996 a rdfs:Class ;
  rdfs:label "vagina" ;
  rdfs:comment "A fibromuscular tubular tract leading from the uterus to the exterior of the body in female placental mammals and marsupials, or to the cloaca in female birds, monotremes, and some reptiles[WP]." ;
  rdfs:subClassOf obo:UBERON_0000064 .

obo:OBIB_0000176 a rdfs:Class ;
  rdfs:label "left partial nephrectomy" ;
  rdfs:comment "A surgical procedure to remove part of the left kidney." ;
  rdfs:subClassOf obo:OBIB_0000716 .

obo:OBIB_0000042 a rdfs:Class ;
  rdfs:label "average daily use of cigarette datum"@en ;
  rdfs:comment "An average value of use of cigarettes per day." ;
  rdfs:subClassOf obo:OBI_0000679 .

obo:NCIT_C40080 a rdfs:Class ;
  rdfs:label "Borderline Ovarian Clear Cell Tumor" ;
  rdfs:comment "An epithelial neoplasm with low malignant potential affecting the ovary.  It is characterized by the presence of clear or hobnail cells.  In some cases, the cells may display nuclear atypia and prominent nucleoli.  When such cells are present, they remain confined to the glands.  There is no evidence of stromal invasion." ;
  rdfs:subClassOf obo:DOID_0050934 .

obo:CHEBI_38870 a rdfs:Class ;
  rdfs:label "inhalation anaesthetic" ;
  rdfs:subClassOf obo:CHEBI_38867 .

obo:OBI_0000272 a rdfs:Class ;
  rdfs:label "protocol"@en ;
  rdfs:comment "A plan specification which has sufficient level of detail and quantitative information to communicate it between investigation agents, so that different investigation agents will reliably be able to independently reproduce the process."@en ;
  rdfs:subClassOf obo:IAO_0000104 .

obo:CHEBI_50919 a rdfs:Class ;
  rdfs:label "antiemetic" ;
  rdfs:comment "A drug used to prevent nausea or vomiting. An antiemetic may act by a wide range of mechanisms: it might affect the medullary control centres (the vomiting centre and the chemoreceptive trigger zone) or affect the peripheral receptors." ;
  rdfs:subClassOf obo:OGMS_0000148 .

obo:OBIB_0000382 a rdfs:Class ;
  rdfs:label "date and time FFPE tissue was preserved" ;
  rdfs:comment "A data item indicating the date and time when a specimen tissue was fixed or frozen as part of a formalin-fixed paraffin-embedded (FFPE) process." ;
  rdfs:subClassOf obo:IAO_0000027 .

obo:OMIABIS_0000046 a rdfs:Class ;
  rdfs:label "obsolete CTEP organization identifier" ;
  rdfs:subClassOf <http://www.geneontology.org/formats/oboInOwl#ObsoleteClass> .

obo:OBI_0002460 a rdfs:Class ;
  rdfs:label "defined population inclusion criterion"@en ;
  rdfs:comment "An inclusion criterion that is based on fitting within the defined characteristics of a population based study design." ;
  rdfs:subClassOf obo:OBI_0500027 .

obo:OBI_0002653 a rdfs:Class ;
  rdfs:label "ultrasound-guided needle biopsy" ;
  rdfs:comment "A needle biopsy guided by ultrasound visualization." ;
  rdfs:subClassOf obo:OBI_0002651 .

obo:OBIB_0000028 a rdfs:Class ;
  rdfs:label "collection packet"@en ;
  rdfs:comment "A material entity used for specimen collection. It can contain a container to hold a specimen and material (e.g. paper) carrying information about the specimen and the specimen source (e.g. patient)." ;
  rdfs:subClassOf obo:BFO_0000040 .

obo:OMIABIS_0000050 a rdfs:Class ;
  rdfs:label "obsolete fixed tissue specimen" ;
  rdfs:subClassOf <http://www.geneontology.org/formats/oboInOwl#ObsoleteClass> .

obo:OBI_0000458 a rdfs:Class ;
  rdfs:label "manufacturing objective"@en ;
  rdfs:comment "is the objective to manufacture a material of a certain function (device)"@en ;
  rdfs:subClassOf obo:OBI_0000456 .

obo:OMIABIS_0001080 a rdfs:Class ;
  rdfs:label "obsolete sample handling" ;
  rdfs:subClassOf <http://www.geneontology.org/formats/oboInOwl#ObsoleteClass> .

obo:OBIB_0000399 a rdfs:Class ;
  rdfs:label "percentage of tumor slide specimen stroma by surface area" ;
  rdfs:comment "A data item that is the result of determining the percentage of a tumor slide specimen that is stroma based on surface area." ;
  rdfs:subClassOf obo:IAO_0000027 .

obo:OBI_0002089 a rdfs:Class ;
  rdfs:label "physical store" ;
  rdfs:comment "A container with an environmental control function." ;
  rdfs:subClassOf obo:OBI_0000967 , obo:OBI_0001034 .

obo:OMIABIS_0001010 a rdfs:Class ;
  rdfs:label "obsolete count of current sampled human study participant" ;
  rdfs:subClassOf <http://www.geneontology.org/formats/oboInOwl#ObsoleteClass> .

obo:UBERON_0007106 a rdfs:Class ;
  rdfs:label "chorionic villus" ;
  rdfs:comment "One of the minute vascular projections of the fetal chorion that combines with maternal uterine tissue to form the placenta." ;
  rdfs:subClassOf obo:UBERON_0000465 .

obo:OBI_0002545 a rdfs:Class ;
  rdfs:label "ileum specimen" ;
  rdfs:comment "A specimen that is derived from ileum." ;
  rdfs:subClassOf obo:OBI_0001479 .

obo:OBIB_0000035 a rdfs:Class ;
  rdfs:label "blood spotting"@en ;
  rdfs:comment "An adding specimen into a container process that spots the blood from an organism on the blood spot card." ;
  rdfs:subClassOf obo:OBIB_0000034 .

obo:UBERON_0000477 a rdfs:Class ;
  rdfs:label "anatomical cluster" ;
  rdfs:comment "Anatomical group that has its parts adjacent to one another." ;
  rdfs:subClassOf obo:BFO_0000040 .

obo:OBI_2000008 a rdfs:Class ;
  rdfs:label "semen specimen" ;
  rdfs:comment "A specimen that is derived from some semen" ;
  rdfs:subClassOf obo:OBI_0001479 .

obo:BFO_0000001 a rdfs:Class ;
  rdfs:label "entity"@en .

obo:OMIABIS_0000028 a rdfs:Class ;
  rdfs:label "obsolete ISO 3166-1 alpha-2 code for biobank contact person" ;
  rdfs:subClassOf <http://www.geneontology.org/formats/oboInOwl#ObsoleteClass> .

obo:OBI_0000017 a rdfs:Class ;
  rdfs:label "regulatory role"@en ;
  rdfs:comment "a role which inheres in material entities and is realized in the processes of making, enforcing or being defined by legislation or orders issued by a governmental body."@en ;
  rdfs:subClassOf obo:BFO_0000023 .

obo:OBIB_0000537 a rdfs:Class ;
  rdfs:label "previous colorectal polyps colorectal cancer risk factor" ;
  rdfs:comment "A colorectal cancer risk factor that is having had colorectal polyps." ;
  rdfs:subClassOf obo:OBIB_0000533 .

obo:OBIB_0000139 a rdfs:Class ;
  rdfs:label "amount of packed red blood cells administered intraoperatively" ;
  rdfs:comment "A count of the number of units of packed red blood cells administered during surgery." ;
  rdfs:subClassOf obo:APOLLO_SV_00000032 .

obo:OBI_0000399 a rdfs:Class ;
  rdfs:label "solid support function"@en ;
  rdfs:comment "A solid support function is a function of a device on which an entity is kept in a defined position and prevented in its movement"@en ;
  rdfs:subClassOf obo:BFO_0000034 .

obo:OBIB_0000258 a rdfs:Class ;
  rdfs:label "name of person transferring blood plasma specimens to freezer" ;
  rdfs:comment "A personal name that designates the person who transferred blood plasma specimens to freezer." ;
  rdfs:subClassOf obo:IAO_0020015 .

obo:OBIB_0000442 a rdfs:Class ;
  rdfs:label "minimum required pre-operative RNA and DNA PAXgene tubes were collected" ;
  rdfs:comment "An information content entity that is an indicator of whether the minimum required pre-operative RNA and DNA PAXgene tubes were collected from a donor." ;
  rdfs:subClassOf obo:IAO_0000030 .

obo:OBIB_0000160 a rdfs:Class ;
  rdfs:label "pelvic exenteration" ;
  rdfs:comment "A surgical procedure that removes all organs from a person's pelvic cavity including the urinary bladder, urethra, rectum, and anus." ;
  rdfs:subClassOf obo:OBIB_0000716 .

obo:OBI_2000007 a rdfs:Class ;
  rdfs:label "nasopharynx specimen" ;
  rdfs:comment "A specimen that is derived from some nasopharynx" ;
  rdfs:subClassOf obo:OBI_0001479 .

obo:OBIB_0000128 a rdfs:Class ;
  rdfs:label "rectosigmoidectomy" ;
  rdfs:comment "A colectomy that is the surgical removal of the rectum and sigmoid colon." ;
  rdfs:subClassOf obo:OAE_0001159 .

obo:OBIB_0000100 a rdfs:Class ;
  rdfs:label "date of surgical removal of specimen" ;
  rdfs:comment "A date of specimen collection on which the surgery was performed during which the specimen was collected." ;
  rdfs:subClassOf obo:OBIB_0000714 .

obo:NCBITaxon_11676 a rdfs:Class ;
  rdfs:label "Human immunodeficiency virus 1" ;
  rdfs:subClassOf obo:NCBITaxon_11646 .

obo:OBI_0000967 a rdfs:Class ;
  rdfs:label "container" ;
  rdfs:comment "A device that can be used to restrict the location of material entities over time" ;
  rdfs:subClassOf obo:OBI_0000968 .

obo:OBI_0002551 a rdfs:Class ;
  rdfs:label "suprapubic skin specimen" ;
  rdfs:comment "A specimen that is derived from suprapubic skin." ;
  rdfs:subClassOf obo:OBI_0002526 .

obo:OBIB_0000079 a rdfs:Class ;
  rdfs:label "blood draw time" ;
  rdfs:comment "A data item that reports the time of day when a blood specimen was collected." ;
  rdfs:subClassOf obo:IAO_0000027 .

obo:OBIB_0000309 a rdfs:Class ;
  rdfs:label "FFPE tissue paraffin embedding SOP" ;
  rdfs:comment "A standard operating procedure for the paraffin embedding of a formalin-fixed paraffin-embedded (FFPE) tissue." ;
  rdfs:subClassOf obo:OBIB_0000070 .

obo:OMIABIS_0000039 a rdfs:Class ;
  rdfs:label "obsolete name of sample collection or study contact person" ;
  rdfs:subClassOf <http://www.geneontology.org/formats/oboInOwl#ObsoleteClass> .

obo:OBI_0002507 a rdfs:Class ;
  rdfs:label "saliva specimen" ;
  rdfs:comment "A specimen that is derived from saliva." ;
  rdfs:subClassOf obo:OBI_0001479 .

obo:OBI_0000338 a rdfs:Class ;
  rdfs:label "drawing a conclusion based on data"@en ;
  rdfs:comment "A planned process in which data gathered in an investigation is evaluated in the context of existing knowledge with the objective to generate more general conclusions or to conclude that the data does not allow one to draw general conclusion"@en ;
  rdfs:subClassOf obo:OBI_0000011 .

obo:OBIB_0000655 a rdfs:Class ;
  rdfs:label "postal code for sample collection or study contact"@en ;
  rdfs:comment "Postal code that is part of the address of a human being serving as sample collection or study contact."@en ;
  rdfs:subClassOf obo:IAO_0000646 .

obo:OBIB_0000031 a rdfs:Class ;
  rdfs:label "cryovial"@en ;
  rdfs:comment "A test tube that designed to store materials at very low temperatures." ;
  rdfs:subClassOf obo:OBI_0000967 .

obo:OBI_0002518 a rdfs:Class ;
  rdfs:label "prostate gland specimen" ;
  rdfs:comment "A specimen that is derived from prostate gland." ;
  rdfs:subClassOf obo:OBI_0001479 .

obo:OBI_0002522 a rdfs:Class ;
  rdfs:label "adrenal gland specimen" ;
  rdfs:comment "A specimen that is derived from adrenal gland." ;
  rdfs:subClassOf obo:OBI_0001479 .

obo:IAO_0000414 a rdfs:Class ;
  rdfs:label "mass measurement datum"@en ;
  rdfs:comment "A scalar measurement datum that is the result of measurement of mass quality"@en ;
  rdfs:subClassOf obo:IAO_0000032 .

obo:OBIB_0000499 a rdfs:Class ;
  rdfs:label "time since radiation therapy was received prior to surgery" ;
  rdfs:comment "A time measurement datum that is the result of measuring the time elapsed since radiation therapy prior to surgery." ;
  rdfs:subClassOf obo:IAO_0000416 .

obo:BFO_0000026 a rdfs:Class ;
  rdfs:label "one-dimensional spatial region"@en ;
  rdfs:subClassOf obo:BFO_0000006 .

obo:OBIB_0000640 a rdfs:Class ;
  rdfs:label "ISO 3166-1 alpha-2 code for biobank contact person"@en ;
  rdfs:comment "The ISO 3166-1 alpha-2 code that is part of the biobank contact person's postal address."@en ;
  rdfs:subClassOf obo:OBIB_0000620 .

obo:NCBITaxon_9606 a rdfs:Class ;
  rdfs:label "Homo sapiens" ;
  rdfs:subClassOf obo:NCBITaxon_314146 .

obo:OBIB_0000246 a rdfs:Class ;
  rdfs:label "name of person storing specimen" ;
  rdfs:comment "A personal name that designates the person who stored a specimen." ;
  rdfs:subClassOf obo:IAO_0020015 .

obo:OBI_1000024 a rdfs:Class ;
  rdfs:label "cell pellet"@en ;
  rdfs:comment "A material entity which results from the aggregation of cells produced by the application of centrifugal force to a liquid containing cells in suspension"@en ;
  rdfs:subClassOf obo:OBI_0000047 .

obo:OBI_0600038 a rdfs:Class ;
  rdfs:label "addition of molecular label"@en ;
  rdfs:comment "a material processing technique intended to add a molecular label to some input material entity, to allow detection of the molecular target of this label in a detection of molecular label assay"@en ;
  rdfs:subClassOf obo:OBI_0000094 .

obo:OBI_0000260 a rdfs:Class ;
  rdfs:label "plan"@en ;
  rdfs:comment "A plan is a realizable entity that is the inheres in a bearer who is committed to realizing it as a planned process."@en ;
  rdfs:subClassOf obo:BFO_0000017 .

obo:UBERON_0001043 a rdfs:Class ;
  rdfs:label "esophagus" ;
  rdfs:comment "Tube that connects the pharynx to the stomach. In mammals, the oesophagus connects the buccal cavity with the stomach. The stratified squamous non-keratinised epithelium lining the buccal cavity is continued through the pharynx down into the oesophagus. The lowest part of the oesophagus (ca. 2 cm) is lined with gastric mucosa and covered by peritoneum. The main body of the oesophagus is lined with small, simple mucous glands. Each gland opens into the lumen by a long duct which pierces the muscularis mucosae (Wilson and Washington, 1989). A sphincter is situated at the point where the oesophagus enters the stomach to prevent gastro-oesophageal reflux, i.e. to prevent acidic gastric contents from reaching stratified epithelia of the oesophagus, where they can cause inflammation and irritation (Wilson and Washington, 1989; Brown et al., 1993)." ;
  rdfs:subClassOf obo:UBERON_0000465 .

obo:OBIB_0000245 a rdfs:Class ;
  rdfs:label "time of specimen freezing at -70 to -80 degrees C" ;
  rdfs:comment "A time of specimen freezing which occurred at -75�_ �� 5�_C." ;
  rdfs:subClassOf obo:OBIB_0000724 .

obo:UBERON_0001134 a rdfs:Class ;
  rdfs:label "skeletal muscle tissue" ;
  rdfs:comment "Muscle tissue that consists primarily of skeletal muscle fibers." ;
  rdfs:subClassOf obo:UBERON_0000479 .

obo:OBI_0002197 a rdfs:Class ;
  rdfs:label "tissue section thickness"@en ;
  rdfs:comment "A length measurement datum that is the result of an assay measuring the thickness of a tissue section." ;
  rdfs:subClassOf obo:IAO_0000408 .

obo:OBIB_0000170 a rdfs:Class ;
  rdfs:label "supracervical hysterectomy" ;
  rdfs:comment "A surgical procedure in which the body of the uterus is removed but the cervix is kept intact, as compared to the more common total hysterectomy, in which the uterus, cervix and fundus (the part of the uterus above the fallopian tube openings) are removed." ;
  rdfs:subClassOf obo:OBIB_0000716 .

obo:OBI_0002444 a rdfs:Class ;
  rdfs:label "measurand role"@en ;
  rdfs:comment "A role borne by a material entity and realized in an assay which achieves the objective to measure the magnitude/concentration/amount of the measurand in the entity bearing evaluant role." ;
  rdfs:subClassOf obo:OMRSE_00000048 .

obo:OBIB_0000482 a rdfs:Class ;
  rdfs:label "specimen donor's date of birth" ;
  rdfs:comment "A date of birth that signifies the calendar date on which a particular donor of a specimen was born." ;
  rdfs:subClassOf <http://www.ebi.ac.uk/efo/EFO_0004950> .

obo:UBERON_0002358 a rdfs:Class ;
  rdfs:label "peritoneum" ;
  rdfs:comment "A serous membrane that lines the peritoneal cavity[VHOG,modified]." ;
  rdfs:subClassOf obo:UBERON_0000064 .

obo:OBI_0002421 a rdfs:Class ;
  rdfs:label "indicator of whether an inclusion criterion was met" ;
  rdfs:comment "An information content entity that indicates whether or not  an entity has met a specific requirement in order to take part in a given process." ;
  rdfs:subClassOf obo:IAO_0000030 .

obo:OBIB_0000207 a rdfs:Class ;
  rdfs:label "ending time of parent specimen dissection." ;
  rdfs:comment "A data item indicating the time that the dissection of a specimen for specimen family creation ended." ;
  rdfs:subClassOf obo:IAO_0000027 .

obo:OBIB_0000239 a rdfs:Class ;
  rdfs:label "data and time of laboratory receipt of specimen" ;
  rdfs:comment "A data item indicating the date and time at which the specimen was received in the laboratory for processing." ;
  rdfs:subClassOf obo:IAO_0000027 .

obo:OBI_0002511 a rdfs:Class ;
  rdfs:label "vitreous humor specimen" ;
  rdfs:comment "A specimen that is derived from vireous humor." ;
  rdfs:subClassOf obo:OBI_0001479 .

obo:OGMS_0000104 a rdfs:Class ;
  rdfs:label "diagnostic process" ;
  rdfs:comment "A health care process that involves the interpretation of a clinical picture from a given patient (input) and the assertion to the effect that the patient has a disease, disorder, or syndrome of a certain type, or none of these (output)."@en ;
  rdfs:subClassOf obo:OBI_0000011 .

obo:OBIB_0000264 a rdfs:Class ;
  rdfs:label "time of completion of blood cell pellet processing" ;
  rdfs:comment "A data item indicating the time when processing of a blood cell pellet specimen was completed." ;
  rdfs:subClassOf obo:IAO_0000027 .

obo:IDO_0000528 a rdfs:Class ;
  rdfs:label "pathogen"@en ;
  rdfs:comment "A material entity with a pathogenic disposition."@en ;
  rdfs:subClassOf obo:BFO_0000040 .

obo:OBI_0002190 a rdfs:Class ;
  rdfs:label "courier organization"@en ;
  rdfs:comment "An organization that delivers messages, packages, and mail." ;
  rdfs:subClassOf obo:OBI_0000245 .

obo:OBIB_0000698 a rdfs:Class ;
  rdfs:label "population based study design"@en ;
  rdfs:comment "A study design that is multidisciplinary done at the population level or among the population groups, generally to find the cause, incidence or spread of the disease or to see the response to the treatment, nutrition or environment."@en ;
  rdfs:subClassOf obo:OBI_0500000 .

obo:OBIB_0000714 a rdfs:Class ;
  rdfs:label "date of specimen collection"@en ;
  rdfs:comment "A data item that indicates the time when the collection of a specimen occurred."@en ;
  rdfs:subClassOf obo:IAO_0000027 .

obo:NCIT_C16168 a rdfs:Class ;
  rdfs:label "Prior Immunotherapy" ;
  rdfs:comment "Originally, therapeutic administration of serum or gamma globulin containing preformed antibodies produced by another individual; currently, immunotherapy includes nonspecific systemic stimulation, adjuvants, active specific immunotherapy, and adoptive immunotherapy.  New forms of immunotherapy include the use of monoclonal antibodies.  This approach has been widely adopted by cancer specialists, often in cases which fail to respond to other treatment.  Immunotherapy aims to boost immune system function, as with the administration of interferons and interleukin-2, or to attack cancerous cells directly, as with the injection of monoclonal antibodies.  Various immunotherapeutic techniques have also been employed among AIDS patients.  In addition, a number of alternative medical practices are claimed to enhance immune function, and various over-the-counter substances (e.g., goldenseal, lysine have gained popularity for this supposed property." ;
  rdfs:subClassOf obo:OGMS_0000090 .

obo:OBIB_0000192 a rdfs:Class ;
  rdfs:label "wedge resection of left lung" ;
  rdfs:comment "A surgical procedure to remove a triangle-shaped slice of tissue from the left lung. It may be used to remove a tumor or some other type of tissue that requires removal and typically includes a small amount of normal tissue around it." ;
  rdfs:subClassOf obo:OBIB_0000716 .

obo:OBIB_0000162 a rdfs:Class ;
  rdfs:label "bilateral salpingo-oophorectomy" ;
  rdfs:comment "A surgical procedure to remove both ovaries and both fallopian tubes." ;
  rdfs:subClassOf obo:OBIB_0000716 .

obo:OBI_2000015 a rdfs:Class ;
  rdfs:label "capillary blood specimen" ;
  rdfs:comment "A specimen that is derived from some capillary blood" ;
  rdfs:subClassOf obo:OBI_2000009 .

obo:OBIB_0000234 a rdfs:Class ;
  rdfs:label "PAXgene DNA vacutainer" ;
  rdfs:comment "A specimen container developed by PreAnalytiX that is intended to collect, anticoagulate, stabilize, transport, and store a venous whole blood sample for preparation of high quality DNA for use with molecular diagnostic test methods that require DNA." ;
  rdfs:subClassOf obo:OBI_0002088 .

obo:PATO_0000051 a rdfs:Class ;
  rdfs:label "morphology" ;
  rdfs:comment "A quality of a single physical entity inhering in the bearer by virtue of the bearer's size or shape or structure." ;
  rdfs:subClassOf obo:PATO_0001241 .

obo:OBIB_0000644 a rdfs:Class ;
  rdfs:label "intra-settlement specification part of address of biobank contact"@en ;
  rdfs:comment "An intra-settlement specification part of address that is part of a biobank contact's postal address."@en ;
  rdfs:subClassOf obo:OBIB_0000643 .

obo:OMRSE_00000212 a rdfs:Class ;
  rdfs:label "non-binary identity information content entity"@en ;
  rdfs:comment "A gender identity information content entity that is about some person's identifying as non-binary in gender."@en ;
  rdfs:subClassOf obo:OMRSE_00000209 .

obo:OBI_0002989 a rdfs:Class ;
  rdfs:label "material supplier" ;
  rdfs:comment "A person or organization that provides material supplies to other people or organizations." ;
  rdfs:subClassOf obo:BFO_0000040 .

obo:OBI_0001909 a rdfs:Class ;
  rdfs:label "conclusion based on data" ;
  rdfs:comment "An information content entity that is inferred from data." ;
  rdfs:subClassOf obo:IAO_0000030 .

obo:OBI_0000124 a rdf:Property ;
  rdfs:label "is_supported_by_data" ;
  rdfs:comment "The relation between a data item and a conclusion where the conclusion is the output of a data interpreting process and the data item is used as an input to that process" ;
  rdfs:range <https://w3id.org/linkml/Any> .

obo:OBIB_0000436 a rdfs:Class ;
  rdfs:label "time of specimen transfer from pathology gross room to a biobank" ;
  rdfs:comment "A data item indicating the time when a specimen was transferred from a pathology gross room to a biobank." ;
  rdfs:subClassOf obo:IAO_0000027 .

obo:OBIB_0000684 a rdfs:Class ;
  rdfs:label "comorbidity"@en ;
  rdfs:comment "A diagnosis that is the outcome of a diagnostic process targeting a second or additional health problem."@en ;
  rdfs:subClassOf obo:OGMS_0000073 .

obo:OBIB_0000165 a rdfs:Class ;
  rdfs:label "surgical method" ;
  rdfs:comment "A protocol providing the action or system by which the surgical procedure is to be performed." ;
  rdfs:subClassOf obo:OBI_0000272 .

obo:UBERON_0001013 a rdfs:Class ;
  rdfs:label "adipose tissue" ;
  rdfs:comment "Portion of connective tissue composed of adipocytes enmeshed in areolar tissue." ;
  rdfs:subClassOf obo:UBERON_0000479 .

obo:OMIABIS_0000002 a rdfs:Class ;
  rdfs:label "obsolete settlement part of address of sample collection or study contact" ;
  rdfs:subClassOf <http://www.geneontology.org/formats/oboInOwl#ObsoleteClass> .

obo:IAO_8000011 a rdfs:Class ;
  rdfs:label "external import ontology module"@en ;
  rdfs:comment "An imported ontology module that is derived from an external ontology. Derivation methods include the OWLAPI SLME approach."@en ;
  rdfs:subClassOf obo:IAO_8000005 .

obo:NCIT_C126536 a rdfs:Class ;
  rdfs:label "New Zealander" ;
  rdfs:comment "Denotes a person whose ancestry is in the country of New Zealand." ;
  rdfs:subClassOf obo:OBI_0000181 .

obo:OBI_0002370 a rdfs:Class ;
  rdfs:label "unknown clinical history of cancer" ;
  rdfs:comment "A clinical history in which it is not known whether there was a diagnosis of cancer." ;
  rdfs:subClassOf obo:OGMS_0000015 .

obo:UBERON_0001158 a rdfs:Class ;
  rdfs:label "descending colon" ;
  rdfs:comment "The portion of the colon between the left colic flexure and the sigmoid colon at the pelvic brim; the portion of the descending colon lying in the left iliac fossa is sometimes called the iliac colon." ;
  rdfs:subClassOf obo:UBERON_0000064 .

obo:OBI_0002657 a rdfs:Class ;
  rdfs:label "surgical biopsy" ;
  rdfs:comment "A biopsy involving a surgical incision into an organism to access the biopsy material." ;
  rdfs:subClassOf obo:OBI_0002650 .

obo:OBIB_0000117 a rdfs:Class ;
  rdfs:label "time of first surgical incision" ;
  rdfs:comment "A data item that reports the time of day at which the first incision is made during surgery." ;
  rdfs:subClassOf obo:IAO_0000027 .

obo:OBIB_0000062 a rdfs:Class ;
  rdfs:label "collecting specimen from organism during organ donation" ;
  rdfs:comment "A collecting specimen from organism that occurs during the process of organ donation." ;
  rdfs:subClassOf obo:OBI_0600005 .

obo:IAO_0000007 a rdfs:Class ;
  rdfs:label "action specification"@en ;
  rdfs:comment "A directive information entity that describes an action the bearer will take."@en ;
  rdfs:subClassOf obo:IAO_0000033 .

obo:OBIB_0000089 a rdfs:Class ;
  rdfs:label "resolved specimen collection issue" ;
  rdfs:comment "A data item that is an indicator of whether a specimen collection issue is resolved." ;
  rdfs:subClassOf obo:IAO_0000027 .

obo:OBIB_0000666 a rdfs:Class ;
  rdfs:label "microdissected specimen"@en ;
  rdfs:comment "A specimen that has been procured from a histology slide under direct microscopic visualization."@en ;
  rdfs:subClassOf obo:OBI_0100051 .

obo:OBIB_0000269 a rdfs:Class ;
  rdfs:label "date of specimen freezing at -70 to -80 degrees C" ;
  rdfs:comment "A data item indicating the calendar date when a specimen was stored at -75_ � 5_C." ;
  rdfs:subClassOf obo:IAO_0000027 .

obo:OBI_0002404 a rdfs:Class ;
  rdfs:label "no hormonal birth control use history" ;
  rdfs:comment "A hormonal birth control use history that indicates an individual has not ever been a hormonal birth control user." ;
  rdfs:subClassOf obo:OBI_0002401 .

obo:OMIABIS_0000017 a rdfs:Class ;
  rdfs:label "obsolete department" ;
  rdfs:subClassOf <http://www.geneontology.org/formats/oboInOwl#ObsoleteClass> .

obo:OMIABIS_0000061 a rdfs:Class ;
  rdfs:label "obsolete sampling specimens for biobank" ;
  rdfs:subClassOf <http://www.geneontology.org/formats/oboInOwl#ObsoleteClass> .

obo:OBI_0001479 a rdfs:Class ;
  rdfs:label "specimen from organism"@en ;
  rdfs:comment "A specimen that derives from an anatomical part or substance arising from an organism. Examples of tissue specimen include tissue, organ, physiological system, blood, or body location (arm)." ;
  rdfs:subClassOf obo:OBI_0100051 .

obo:CHEBI_65265 a rdfs:Class ;
  rdfs:label "antacid" ;
  rdfs:comment "Any substance which is used to neutralise stomach acidity." ;
  rdfs:subClassOf obo:OGMS_0000148 .

obo:OBIB_0000629 a rdfs:Class ;
  rdfs:label "postal address of biobank contact person"@en ;
  rdfs:comment "Postal address used as a directive for deliveries to the biobank contact person."@en ;
  rdfs:subClassOf obo:IAO_0000422 .

obo:BFO_0000004 a rdfs:Class ;
  rdfs:label "independent continuant"@en ;
  rdfs:comment "b is an independent continuant = Def. b is a continuant which is such that there is no c and no t such that b s-depends_on c at t. (axiom label in BFO2 Reference: [017-002])"@en ;
  rdfs:subClassOf obo:BFO_0000002 .

obo:BFO_0000146 a rdfs:Class ;
  rdfs:label "two-dimensional continuant fiat boundary"@en ;
  rdfs:subClassOf obo:BFO_0000140 .

obo:OBI_0000423 a rdfs:Class ;
  rdfs:label "extract"@en ;
  rdfs:comment "an extract is a material entity which results from an extraction process"@en ;
  rdfs:subClassOf obo:OBI_0000047 .

obo:OBIB_0000378 a rdfs:Class ;
  rdfs:label "FFPE freezing by LN2 vapor phase protocol" ;
  rdfs:comment "A FFPE freezing protocol that involves the use of liquid nitrogen vapor phase." ;
  rdfs:subClassOf obo:OBI_0000272 .

obo:OBIB_0000618 a rdfs:Class ;
  rdfs:label "settlement part of address of sample collection or study contact"@en ;
  rdfs:comment "The part of a sample collection or study contact's adress denoting a settlement."@en ;
  rdfs:subClassOf obo:OBIB_0000641 .

obo:CHEBI_8776 a rdfs:Class ;
  rdfs:label "ranitidine" ;
  rdfs:comment "A member of the class of  furans used to treat  peptic ulcer disease (PUD) and gastroesophageal reflux disease." ;
  rdfs:subClassOf obo:CHEBI_23367 .

obo:BFO_0000015 a rdfs:Class ;
  rdfs:label "process"@en ;
  rdfs:comment "p is a process = Def. p is an occurrent that has temporal proper parts and for some time t, p s-depends_on some material entity at t. (axiom label in BFO2 Reference: [083-003])"@en ;
  rdfs:subClassOf obo:BFO_0000003 .

obo:UBERON_0001264 a rdfs:Class ;
  rdfs:label "pancreas" ;
  rdfs:comment "An endoderm derived structure that produces precursors of digestive enzymes and blood glucose regulating hormones[GO]." ;
  rdfs:subClassOf obo:UBERON_0000465 .

obo:OBIB_0000725 a rdfs:Class ;
  rdfs:label "time of surgical removal of specimen"@en ;
  rdfs:comment "A data item that reports the time when a specimen was collected by a surgical procedure."@en ;
  rdfs:subClassOf obo:IAO_0000027 .

obo:OBIB_0000086 a rdfs:Class ;
  rdfs:label "specimen collected with specific collection packet" ;
  rdfs:comment "A specimen from organism that is collected with a collection packet that is designed to collect specimens of a particular type for a particular purpose." ;
  rdfs:subClassOf obo:OBI_0001479 .

obo:OBI_0002663 a rdfs:Class ;
  rdfs:label "skinpunch biopsy" ;
  rdfs:comment "A biopsy that involves the collection of a cylinder of skin (including epidermis, dermis and superficial fat) using a punch tool." ;
  rdfs:subClassOf obo:OBI_0002650 .

obo:UBERON_0000473 a rdfs:Class ;
  rdfs:label "testis" ;
  rdfs:comment "A gonad of a male animal. A gonad produces and releases sperm." ;
  rdfs:subClassOf obo:UBERON_0000465 .

obo:NCBITaxon_33154 a rdfs:Class ;
  rdfs:label "Opisthokonta" ;
  rdfs:subClassOf obo:NCBITaxon_2759 .

obo:OMIABIS_0001079 a rdfs:Class ;
  rdfs:label "obsolete specimen donor" ;
  rdfs:subClassOf <http://www.geneontology.org/formats/oboInOwl#ObsoleteClass> .

obo:OBIB_0000068 a rdfs:Class ;
  rdfs:label "collection packet identifier" ;
  rdfs:comment "An identifier that refers to a collection packet used in a specimen collection process." ;
  rdfs:subClassOf obo:IAO_0020000 .

obo:UBERON_0001621 a rdfs:Class ;
  rdfs:label "coronary artery" ;
  rdfs:comment "An artery that supplies the myocardium." ;
  rdfs:subClassOf obo:UBERON_0000465 .

obo:OBIB_0000548 a rdfs:Class ;
  rdfs:label "clinical history of abnormal white blood cell levels" ;
  rdfs:comment "A clinical history in which there is a history of abnormal white blood cell levels." ;
  rdfs:subClassOf obo:OGMS_0000015 .

obo:UBERON_0004538 a rdfs:Class ;
  rdfs:label "left kidney" ;
  rdfs:comment "A kidney that is part of a left side of organism [Automatically generated definition]." ;
  rdfs:subClassOf obo:UBERON_0002113 .

obo:OMRSE_00000204 a rdfs:Class ;
  rdfs:label "social identity information content entity"@en ;
  rdfs:comment "An information content entity that is intended to be a truthful statement about some person and whether that person identifies as some particular aspect of social identity—such as a gender, an ethnicity, a race, or a sexual orientation—where the sense of identifying may correspond to either (i) an aspect of one’s cognitive representation of oneself, (ii) how one prefers to be regarded by others within some social context, or (iii) how one chooses to present oneself to others within some social context."@en ;
  rdfs:subClassOf obo:IAO_0000030 .

obo:OMIABIS_0001009 a rdfs:Class ;
  rdfs:label "obsolete primary diagnosis" ;
  rdfs:subClassOf <http://www.geneontology.org/formats/oboInOwl#ObsoleteClass> .

obo:OBIB_0000324 a rdfs:Class ;
  rdfs:label "charged glass slide indicator" ;
  rdfs:comment "An information content entity that indicates that a glass slide has been positively charged." ;
  rdfs:subClassOf obo:IAO_0000030 .

obo:CHEBI_33281 a rdfs:Class ;
  rdfs:label "antimicrobial agent" ;
  rdfs:comment "A substance that kills or slows the growth of microorganisms, including bacteria, viruses, fungi and protozoans." ;
  rdfs:subClassOf obo:OGMS_0000148 .

obo:OMIABIS_0000024 a rdfs:Class ;
  rdfs:label "obsolete post-office box" ;
  rdfs:subClassOf <http://www.geneontology.org/formats/oboInOwl#ObsoleteClass> .

obo:OBI_0002605 a rdfs:Class ;
  rdfs:label "cheek swab specimen" ;
  rdfs:comment "A specimen that is collected with a swab from the cheek portion of the inside surface of a mouth." ;
  rdfs:subClassOf obo:OBI_0002599 .

obo:OBIB_0000075 a rdfs:Class ;
  rdfs:label "SOP adjustment" ;
  rdfs:comment "A protocol that provides deviations or changes to part of an existing standard operating procedure." ;
  rdfs:subClassOf obo:OBI_0000272 .

obo:CLO_0000001 a rdfs:Class ;
  rdfs:label "cell line cell" ;
  rdfs:comment """A cultured cell that is part of a cell line - a stable and homogeneous population of cells with a common biological origin and propagation history in culture
""" ;
  rdfs:subClassOf obo:OBI_0001866 .

obo:CHEBI_5790 a rdfs:Class ;
  rdfs:label "hydromorphone" ;
  rdfs:comment "A  morphinane alkaloid that is a hydrogenated ketone derivative of morphine. A semi-synthetic drug, it is a centrally acting pain medication of the opioid class." ;
  rdfs:subClassOf obo:CHEBI_23367 .

obo:OBI_0002540 a rdfs:Class ;
  rdfs:label "coronary artery specimen" ;
  rdfs:comment "A specimen that is derived from coronary artery." ;
  rdfs:subClassOf obo:OBI_0001479 .

obo:OBIB_0000532 a rdfs:Class ;
  rdfs:label "comment on exposure to environmental and workplace carcinogens" ;
  rdfs:comment "A textual entity that states additional information relevant to the history of exposure to environmental and workplace carcinogens." ;
  rdfs:subClassOf obo:IAO_0000300 .

obo:NCIT_C45504 a rdfs:Class ;
  rdfs:label "Lung Squamous Cell Carcinoma, Small Cell Variant" ;
  rdfs:comment "A poorly differentiated morphologic variant of squamous cell lung carcinoma characterized by the presence of small tumor cells with focal squamous differentiation." ;
  rdfs:subClassOf obo:DOID_3907 .

obo:OMRSE_00000023 a rdfs:Class ;
  rdfs:label "collection of humans"@en ;
  rdfs:comment "An object aggregate all of whose components are human beings."@en ;
  rdfs:subClassOf obo:PCO_0000000 .

obo:OMRSE_00000020 a rdf:Property ;
  rdfs:label "is-aggregate-of" ;
  rdfs:comment """We anticipate BFO 2.0 including and defining this relation.  When it does, we will obsolete this property and declare it equivalent to the BFO 2.0 relation.
"""@en ;
  rdfs:range <https://w3id.org/linkml/Any> .

obo:IAO_0000029 a rdfs:Class ;
  rdfs:label "numeral"@en ;
  rdfs:comment "A symbol that denotes a number."@en ;
  rdfs:subClassOf obo:IAO_0000028 .

obo:OBI_0200166 a rdfs:Class ;
  rdfs:label "data transformation objective"@en ;
  rdfs:comment "An objective specification to transformation input data into output data"@en ;
  rdfs:subClassOf obo:IAO_0000005 .

obo:OBIB_0000202 a rdfs:Class ;
  rdfs:label "name of biobank person receiving specimen" ;
  rdfs:comment "A personal name that designates the person who received a specimen in the biobank." ;
  rdfs:subClassOf obo:IAO_0020015 .

obo:UBERON_0000945 a rdfs:Class ;
  rdfs:label "stomach" ;
  rdfs:comment "An expanded region of the vertebrate alimentary tract that serves as a food storage compartment and digestive organ. A stomach is lined, in whole or in part by a glandular epithelium." ;
  rdfs:subClassOf obo:UBERON_0000465 .

obo:OBI_0002599 a rdfs:Class ;
  rdfs:label "swab specimen" ;
  rdfs:comment "A specimen that is stored on a swab as the output of a collecting specimen with swab process." ;
  rdfs:subClassOf obo:OBI_0100051 .

obo:OBIB_0000111 a rdfs:Class ;
  rdfs:label "administration of inhalation anaesthetic" ;
  rdfs:comment "A planned process to administer anaesthetic in the form of a gas aerosol or fine powder via the respiratory tract usually by oral or nasal inhalation for local or systemic effect." ;
  rdfs:subClassOf obo:OBI_0000011 .

obo:CHEBI_38867 a rdfs:Class ;
  rdfs:label "anaesthetic" ;
  rdfs:comment "Substance which produces loss of feeling or sensation." ;
  rdfs:subClassOf obo:OGMS_0000148 .

obo:OBI_0002527 a rdfs:Class ;
  rdfs:label "pancreas specimen" ;
  rdfs:comment "A specimen that is derived from pancreas." ;
  rdfs:subClassOf obo:OBI_0001479 .

obo:OBIB_0000143 a rdfs:Class ;
  rdfs:label "specimen donor intraoperative blood loss prior to organ excision volume measurement datum" ;
  rdfs:comment "A specimen donor intraoperative blood loss volume measurement datum obtained prior to organ excision." ;
  rdfs:subClassOf obo:OBIB_0000142 .

obo:IAO_0020024 a rdfs:Class ;
  rdfs:label "credential role"@en ;
  rdfs:comment "A role that inheres in a concretization of an identity document and is realized by an authentication process."@en ;
  rdfs:subClassOf obo:BFO_0000023 .

obo:OBIB_0000174 a rdfs:Class ;
  rdfs:label "right kidney biopsy" ;
  rdfs:comment "A biopsy of the right kidney." ;
  rdfs:subClassOf obo:OBI_0002650 .

obo:BFO_0000009 a rdfs:Class ;
  rdfs:label "two-dimensional spatial region"@en ;
  rdfs:subClassOf obo:BFO_0000006 .

obo:CHEBI_9939 a rdfs:Class ;
  rdfs:label "vecuronium" ;
  rdfs:comment "A 5alpha-androstane compound having 3alpha-acetoxy-, 17beta-acetoxy-, 2beta-piperidino- and 16beta-N-methylpiperidinium substituents." ;
  rdfs:subClassOf obo:CHEBI_23367 .

obo:OBI_0002410 a rdfs:Class ;
  rdfs:label "menopausal status" ;
  rdfs:comment "An information content entity that indicates the state of a female's cessation of menstruation." ;
  rdfs:subClassOf obo:IAO_0000030 .

obo:OBIB_0000253 a rdfs:Class ;
  rdfs:label "blood plasma specimen volume" ;
  rdfs:comment "A scalar measurement datum that is the output of a volume measurement assay that has a blood plasma specimen as evaluant." ;
  rdfs:subClassOf obo:IAO_0000032 .

obo:OBIB_0000020 a rdfs:Class ;
  rdfs:label "patient questionnaire"@en ;
  rdfs:comment "A questionnaire that comprises a set of demographic and medical questions about a patient which will be filled by the patient or their legally authorized representative." ;
  rdfs:subClassOf obo:OBI_0001000 .

obo:UBERON_0012168 a rdfs:Class ;
  rdfs:label "umbilical cord blood" ;
  rdfs:comment "Blood that remains in the placenta and in the attached umbilical cord after childbirth[WP]." ;
  rdfs:subClassOf obo:UBERON_0000178 .

obo:DOID_0050933 a rdfs:Class .

obo:BFO_0000028 a rdfs:Class ;
  rdfs:label "three-dimensional spatial region"@en ;
  rdfs:subClassOf obo:BFO_0000006 .

obo:OBI_0002679 a rdfs:Class ;
  rdfs:label "vacuum-assisted biopsy needle" ;
  rdfs:comment "A core biopsy needle integrated with a vacuum system which facilitates the collection of specimen material." ;
  rdfs:subClassOf obo:OBI_0000436 .

obo:OBI_0001930 a rdfs:Class ;
  rdfs:label "categorical value specification" ;
  rdfs:comment "A value specification that is specifies one category out of a fixed number of nominal categories" ;
  rdfs:subClassOf obo:OBI_0001933 .

obo:UBERON_0001557 a rdfs:Class ;
  rdfs:label "upper respiratory tract" ;
  rdfs:comment "The segment of the respiratory tract that starts proximally with the nose and ends distally with the cricoid cartilage, before continuing to the trachea." ;
  rdfs:subClassOf obo:UBERON_0000465 .

obo:CHEBI_23367 a rdfs:Class ;
  rdfs:label "molecular entity" ;
  rdfs:comment "Any constitutionally or isotopically distinct atom, molecule, ion, ion pair, radical, radical ion, complex, conformer etc., identifiable as a separately distinguishable entity." ;
  rdfs:subClassOf obo:BFO_0000040 .

obo:OBIB_0000212 a rdfs:Class ;
  rdfs:label "PAXgene fixation reagent" ;
  rdfs:comment "A processed material that is a non-carcinogenic, non-cross-linking mixture of different alcohols, acid and a soluble organic compound that rapidly preserves morphology and all bio-molecules." ;
  rdfs:subClassOf obo:OBI_0000047 .

obo:OBI_0000915 a rdfs:Class ;
  rdfs:label "freezing storage" ;
  rdfs:comment "A storage process in temperature that maintenance the frozen status of the stored entities." ;
  rdfs:subClassOf obo:OBI_0302893 .

obo:OBI_2000012 a rdfs:Class ;
  rdfs:label "umbilical cord blood specimen" ;
  rdfs:comment "A specimen that is derived from some umbilical cord blood" ;
  rdfs:subClassOf obo:OBI_2000013 .

obo:OBI_0000079 a rdfs:Class ;
  rdfs:label "culture medium"@en ;
  rdfs:comment "a processed material that provides the needed nourishment for microorganisms or cells grown in vitro." ;
  rdfs:subClassOf obo:OBI_0000047 .

obo:OBIB_0002005 a rdfs:Class ;
  rdfs:label "specimen gross appearance of metastatic tumor"@en ;
  rdfs:comment "A specimen gross appearance of a tumor that has spread from its original site by discontinuous (not direct) spread, e.g. by blood or lymphatics." ;
  rdfs:subClassOf obo:OBIB_0000209 .

obo:CHEBI_61219 a rdfs:Class ;
  rdfs:label "succinylcholine chloride (anhydrous)" ;
  rdfs:comment "A chloride salt in which the negative charge of the chloride ions is balanced by succinylcholine dications." ;
  rdfs:subClassOf obo:CHEBI_23367 .

obo:UBERON_0013757 a rdfs:Class ;
  rdfs:label "capillary blood" ;
  rdfs:comment "A blood that is part of a capillary." ;
  rdfs:subClassOf obo:UBERON_0000178 .

obo:OBI_0200170 a rdfs:Class ;
  rdfs:label "averaging data transformation"@en ;
  rdfs:comment "An averaging data transformation is a data transformation that has objective averaging."@en ;
  rdfs:subClassOf obo:OBI_0200000 .

obo:OBIB_0000288 a rdfs:Class ;
  rdfs:label "FFPE tissue processing SOP" ;
  rdfs:comment "A standard operating procedure for fixation of a tissue to the state where it is completely infiltrated with a suitable histological wax and can be embedded ready for section cutting on the microtome for a formalin-fixed paraffin-embedded (FFPE) process." ;
  rdfs:subClassOf obo:OBIB_0000070 .

obo:OMRSE_00000215 a rdfs:Class ;
  rdfs:label "OMB American Indian or Alaska Native identity information content entity"@en ;
  rdfs:comment "An OMB racial identity information content entity that is about some person's identifying as American Indian or Alaska Native, which is intended to mean having origins in any of the original peoples of North and South America (including Central America), and maintains tribal affiliation or community attachment."@en ;
  rdfs:subClassOf obo:OMRSE_00000214 .

obo:OBIB_0000720 a rdfs:Class ;
  rdfs:label "specimen freezing"@en ;
  rdfs:comment "A freezing storage for the specimen."@en ;
  rdfs:subClassOf obo:OBI_0000915 .

obo:OBI_2000003 a rdfs:Class ;
  rdfs:label "throat specimen" ;
  rdfs:comment "A specimen that is derived from some throat" ;
  rdfs:subClassOf obo:OBI_0001479 .

obo:OBIB_0000491 a rdfs:Class ;
  rdfs:label "authorization for postmortem specimen donation for transplantation purposes only" ;
  rdfs:comment "An authorization documentation for postmortem specimen donation for a specified purpose which is solely for the purpose of transplantation to another person or persons." ;
  rdfs:subClassOf obo:OBIB_0000490 .

obo:OBIB_0000092 a rdfs:Class ;
  rdfs:label "specimen donor body refrigerated indicator" ;
  rdfs:comment "A data item indicating whether the body of the specimen donor was refrigerated after death but prior to specimen collection." ;
  rdfs:subClassOf obo:IAO_0000027 .

obo:OBI_0000378 a rdfs:Class ;
  rdfs:label "filter function"@en ;
  rdfs:comment "A filter function is a function to prevent the flow of certain entities based on a quality or qualities of the entity while allowing entities which have different qualities to pass through"@en ;
  rdfs:subClassOf obo:OBI_0000372 .

obo:OBIB_0000285 a rdfs:Class ;
  rdfs:label "name of quality control inspector of specimen" ;
  rdfs:comment "A personal name that designates the person who performed a quality control inspection of the specimen that is to be transported to another organization." ;
  rdfs:subClassOf obo:IAO_0020015 .

obo:OBIB_0000106 a rdfs:Class ;
  rdfs:label "administration of local anaesthetic" ;
  rdfs:comment "A planned process to administer anaesthetic to a restricted or localized area in order to produce a loss of feeling." ;
  rdfs:subClassOf obo:OBI_0000011 .

obo:OBIB_0000420 a rdfs:Class ;
  rdfs:label "resected tissue specimen mass measurement datum" ;
  rdfs:comment "A mass measurement datum that is the output of an assay to measure the weight of a resected tissue specimen." ;
  rdfs:subClassOf obo:IAO_0000414 .

obo:OBI_0002369 a rdfs:Class ;
  rdfs:label "clinical history devoid of cancer" ;
  rdfs:comment "A clinical history in which there was no diagnosis of cancer." ;
  rdfs:subClassOf obo:OGMS_0000015 .

obo:OBIB_0000614 a rdfs:Class ;
  rdfs:label "indication of residence in state-run group home at time of death" ;
  rdfs:comment "An information content entity in which there is an indication of whether an individual was a resident of a state-run group home at time of death." ;
  rdfs:subClassOf obo:IAO_0000030 .

obo:NCIT_C5651 a rdfs:Class ;
  rdfs:label "Solid Lung Adenocarcinoma" ;
  rdfs:comment "A morphologic variant of lung adenocarcinoma characterized by the presence of polygonal malignant cells forming sheets. Acinar, papillary, micropapillary, or lepidic growth patterns are absent.  If the tumor is 100 percent solid, intracellular mucin should be present in at least five tumor cells in each of two high-power fields and confirmed with mucin immunohistochemical stains. Tumors formerly classified as large cell carcinomas expressing pneumocyte immunohistochemical markers, even if intracellular mucin is absent, are now included in this category." ;
  rdfs:subClassOf obo:DOID_3910 .

obo:UBERON_0001913 a rdfs:Class ;
  rdfs:label "milk" ;
  rdfs:comment "An emulsion of fat globules within a fluid that is secreted by the mammary gland during lactation." ;
  rdfs:subClassOf obo:UBERON_0006314 .

obo:OBIB_0000228 a rdfs:Class ;
  rdfs:label "operating room technician" ;
  rdfs:comment "A health care provider role borne by a person whose duties are to prepare operating rooms, set up equipment and surgical tools, and assist doctors and nurses during surgeries as instructed." ;
  rdfs:subClassOf obo:OMRSE_00000012 .

obo:OBIB_0000275 a rdfs:Class ;
  rdfs:label "name of IATA-trained person verifying specimen transport" ;
  rdfs:comment "A personal name that designates the person who verified the specimen transport was according to best practice, international standards, and industry regulations as trained by the IATA." ;
  rdfs:subClassOf obo:IAO_0020015 .

obo:NCIT_C40088 a rdfs:Class ;
  rdfs:label "Borderline Ovarian Transitional Cell Tumor" ;
  rdfs:comment "An ovarian epithelial neoplasm that resembles the transitional cell neoplasms found in the urinary tract. It is characterized by the presence of atypia and absence of stromal invasion." ;
  rdfs:subClassOf obo:DOID_4000 .

obo:OBIB_0000223 a rdfs:Class ;
  rdfs:label "minimum required pre-operative blood tubes collected" ;
  rdfs:comment "An information content entity indicating whether the minimum requirement according to a standard operating procedure was met for pre-operative blood collection." ;
  rdfs:subClassOf obo:IAO_0000030 .

obo:ERO_0000979 a rdfs:Class ;
  rdfs:subClassOf obo:BFO_0000004 .

obo:OBIB_0000277 a rdfs:Class ;
  rdfs:label "time of receiving specimen transport" ;
  rdfs:comment "A data item indicating the time when a specimen was received after transport from another institution." ;
  rdfs:subClassOf obo:IAO_0000027 .

obo:OBIB_0002001 a rdfs:Class ;
  rdfs:label "specimen integrity"@en ;
  rdfs:comment "A wholeness that inheres in a specimen." ;
  rdfs:subClassOf obo:PATO_0001442 .

obo:OBIB_0000702 a rdfs:Class ;
  rdfs:label "medical record"@en ;
  rdfs:comment "A document that contains information representing health-relevant qualities of a patient written in a chronological manner and that is primarily used for patient care in a clinical setting."@en ;
  rdfs:subClassOf obo:IAO_0000310 .

obo:OBI_0002139 a rdfs:Class ;
  rdfs:label "volume value specification"@en ;
  rdfs:comment "A value specification that specifies the volume of some thing." ;
  rdfs:subClassOf obo:OBI_0001933 .

obo:IAO_0000039 a rdf:Property ;
  rdfs:label "has measurement unit label"@en ;
  rdfs:range obo:UO_0000095 , <https://w3id.org/linkml/Any> ;
  rdfs:subPropertyOf obo:BFO_0000051 .

obo:OBI_0001927 a rdf:Property ;
  rdfs:label "specifies value of" ;
  rdfs:comment "A relation between a value specification and an entity which the specification is about." ;
  rdfs:range <https://w3id.org/linkml/Any> ;
  rdfs:subPropertyOf obo:IAO_0000136 .

obo:FMA_57987 a rdfs:Class ;
  rdfs:label "Right mammary gland" ;
  rdfs:subClassOf obo:UBERON_0000465 .

obo:OMIABIS_0000911 a rdfs:Class ;
  rdfs:label "obsolete fixation" ;
  rdfs:subClassOf <http://www.geneontology.org/formats/oboInOwl#ObsoleteClass> .

obo:OBIB_0000501 a rdfs:Class ;
  rdfs:label "time since immunotherapy was received prior to surgery" ;
  rdfs:comment "A time measurement datum that is the result of measuring the time elapsed since immunotherapy prior to surgery." ;
  rdfs:subClassOf obo:IAO_0000416 .

obo:OBIB_0000217 a rdfs:Class ;
  rdfs:label "commercial manufacturer" ;
  rdfs:comment "A manufacturer that produces materials to be sold for profit." ;
  rdfs:subClassOf obo:OBI_0000835 .

obo:OBIB_0000681 a rdfs:Class ;
  rdfs:label "date of data update"@en ;
  rdfs:comment "A data item that indicates the time when data about the sample collection was last updated in a database."@en ;
  rdfs:subClassOf obo:IAO_0000027 .

obo:OBIB_0000339 a rdfs:Class ;
  rdfs:label "FFPE tissue section H&E clearing protocol" ;
  rdfs:comment "A protocol describing the clearing method used during the hematoxylin and eosin (H&E) stained slide preparation of a formalin-fixed paraffin-embedded (FFPE) tissue section." ;
  rdfs:subClassOf obo:OBI_0000272 .

obo:OBIB_0000181 a rdfs:Class ;
  rdfs:label "right radical nephrectomy" ;
  rdfs:comment "A surgical procedure to remove the entire right kidney." ;
  rdfs:subClassOf obo:OBIB_0000716 .

obo:OBI_0001007 a rdfs:Class ;
  rdfs:label "image creation" ;
  rdfs:comment "A planned process that captures an image of an object." ;
  rdfs:subClassOf obo:OBI_0000011 .

obo:UBERON_0001830 a rdfs:Class ;
  rdfs:label "minor salivary gland" ;
  rdfs:comment "One of the smaller, largely mucus-secreting, exocrine glands of the oral cavity, consisting of the labial, buccal, molar, lingual, and palatine glands[MP]." ;
  rdfs:subClassOf obo:UBERON_0000465 .

obo:OBIB_0000705 a rdfs:Class ;
  rdfs:label "age interval information for sampled donors"@en ;
  rdfs:comment "Age interval information that is age information of specimen donors."@en ;
  rdfs:subClassOf obo:OBIB_0000677 .

obo:OMIABIS_0001038 a rdfs:Class ;
  rdfs:label "obsolete specimen measurement" ;
  rdfs:subClassOf <http://www.geneontology.org/formats/oboInOwl#ObsoleteClass> .

obo:OBIB_0000543 a rdfs:Class ;
  rdfs:label "clinical history of sepsis" ;
  rdfs:comment "A clinical history in which there is a history of sepsis." ;
  rdfs:subClassOf obo:OGMS_0000015 .

obo:OBIB_0000460 a rdfs:Class ;
  rdfs:label "research authorization for post mortem specimen donation was obtained" ;
  rdfs:comment "An information content entity that indicates whether research authorization  for post mortem specimen donation was obtained." ;
  rdfs:subClassOf obo:IAO_0000030 .

obo:OMIABIS_0000013 a rdfs:Class ;
  rdfs:label "obsolete biobank contact person" ;
  rdfs:subClassOf <http://www.geneontology.org/formats/oboInOwl#ObsoleteClass> .

obo:OBI_0500028 a rdfs:Class ;
  rdfs:label "exclusion criterion"@en ;
  rdfs:comment "an exclusion criterion (rule) is_a *eligibility criterion*  which defines and states a condition which, if met, makes an entity unsuitable for a given task or participation in a given process. For instance, in a study protocol, exclusion criteria indicate the conditions that prospective subjects SHOULD NOT meet to be eligible for participation in a study"@en ;
  rdfs:subClassOf obo:OBI_0500026 .

obo:IAO_0000104 a rdfs:Class ;
  rdfs:label "plan specification"@en ;
  rdfs:comment "A directive information entity with action specifications and objective specifications as parts, and that may be concretized as a realizable entity that, if realized, is realized in a process in which the bearer tries to achieve the objectives by taking the actions specified."@en ;
  rdfs:subClassOf obo:IAO_0000033 .

obo:UBERON_0013755 a rdfs:Class ;
  rdfs:label "arterial blood" ;
  rdfs:comment "A blood that is part of a artery." ;
  rdfs:subClassOf obo:UBERON_0000178 .

obo:OBI_0002202 a rdfs:Class ;
  rdfs:label "GX" ;
  rdfs:comment "A cannot be assessed determination for histologic tumor grade." ;
  rdfs:subClassOf obo:OBI_0002200 .

obo:BFO_0000142 a rdfs:Class ;
  rdfs:label "one-dimensional continuant fiat boundary"@en ;
  rdfs:subClassOf obo:BFO_0000140 .

obo:OBIB_0000049 a rdfs:Class ;
  rdfs:label "smoking pipe"@en ;
  rdfs:comment "A device made to allow the user to inhale or taste smoke or vapor derived from the burning or vaporization of some substance." ;
  rdfs:subClassOf obo:OBI_0000967 .

obo:UBERON_0001089 a rdfs:Class ;
  rdfs:label "sweat" ;
  rdfs:comment "Secretion produced by a sweat gland." ;
  rdfs:subClassOf obo:UBERON_0006314 .

<http://www.ebi.ac.uk/efo/EFO_0004953> a rdfs:Class ;
  rdfs:label "date of diagnosis" ;
  rdfs:comment "The point at which a clinical diagnosis is made." ;
  rdfs:subClassOf obo:IAO_0000416 .

obo:OBI_0600024 a rdfs:Class ;
  rdfs:label "maintaining cell culture"@en ;
  rdfs:comment "a protocol application in which cells are kept alive in a defined environment outside of an organism.  part of cell_culturing"@en ;
  rdfs:subClassOf obo:OBI_0000838 .

obo:NCIT_C7100 a rdfs:Class ;
  rdfs:label "Colon Undifferentiated Carcinoma" ;
  rdfs:comment "An invasive malignant epithelial tumor that arises from the colon.  There is no morphologic, immunophenotypic, or molecular biological evidence of glandular or squamous differentiation." ;
  rdfs:subClassOf obo:DOID_1520 .

obo:OBI_0000443 a rdfs:Class ;
  rdfs:label "analyte assay" ;
  rdfs:comment "An assay with the objective to capture information about the presence, concentration, or amount of an analyte in an evaluant." ;
  rdfs:subClassOf obo:OBI_0000070 .

obo:OBIB_0000625 a rdfs:Class ;
  rdfs:label "contact role"@en ;
  rdfs:comment "A role borne by a human being that is part of an group of individuals and acts as contact person for the group. This role gets realized by the bearer being a participant in a contacting process."@en ;
  rdfs:subClassOf obo:OMRSE_00002072 .

obo:CHEBI_16842 a rdfs:Class ;
  rdfs:label "formaldehyde" ;
  rdfs:comment "An aldehyde resulting from the formal oxidation of methanol." ;
  rdfs:subClassOf obo:CHEBI_23367 .

obo:OBIB_0000389 a rdfs:Class ;
  rdfs:label "name of reviewer of pathology case summary report." ;
  rdfs:comment "A personal name that designates the person who served as the reviewer for quality assurance purposes of a pathology case summary report." ;
  rdfs:subClassOf obo:IAO_0020015 .

obo:UBERON_0000956 a rdfs:Class ;
  rdfs:label "cerebral cortex" ;
  rdfs:comment "The thin layer of gray matter on the surface of the cerebral hemisphere that develops from the telencephalon. It consists of the neocortex (6 layered cortex or isocortex), the hippocampal formation and the olfactory cortex." ;
  rdfs:subClassOf obo:UBERON_0000477 .

obo:OBIB_0000602 a rdfs:Class ;
  rdfs:label "clinical history of Multiple Sclerosis" ;
  rdfs:comment "A clinical history in which there is a history of Multiple Sclerosis (MS)." ;
  rdfs:subClassOf obo:OGMS_0000015 .

obo:OBI_0002529 a rdfs:Class ;
  rdfs:label "pituitary gland specimen" ;
  rdfs:comment "A specimen that is derived from pituitary gland." ;
  rdfs:subClassOf obo:OBI_0001479 .

obo:OBIB_0000286 a rdfs:Class ;
  rdfs:label "name of data entry person for tissue recovery form" ;
  rdfs:comment "A personal name that designates the person who performed the data entry process for filling in a tissue recovery case report form." ;
  rdfs:subClassOf obo:IAO_0020015 .

obo:OBIB_0000053 a rdfs:Class ;
  rdfs:label "duration time of smoking"@en ;
  rdfs:comment "A time measurement datum about how long a person has been smoking." ;
  rdfs:subClassOf obo:IAO_0000416 .

obo:IAO_0000413 a rdf:Property ;
  rdfs:label "is duration of"@en ;
  rdfs:comment "relates a process to a time-measurement-datum that represents the duration of the process"@en ;
  rdfs:range <https://w3id.org/linkml/Any> ;
  rdfs:subPropertyOf obo:IAO_0000136 .

obo:OBI_0002500 a rdfs:Class ;
  rdfs:label "amniotic fluid specimen" ;
  rdfs:comment "A specimen that is derived from amniotic fluid." ;
  rdfs:subClassOf obo:OBI_0001479 .

obo:UBERON_0002116 a rdfs:Class ;
  rdfs:label "ileum" ;
  rdfs:comment "The portion of the small intestine that extends from the jejunum to the colon." ;
  rdfs:subClassOf obo:UBERON_0000064 .

obo:OMRSE_00000012 a rdfs:Class ;
  rdfs:label "health care provider role"@en ;
  rdfs:comment "A human health care role inhering in an organization or human being that is realized by a process of providing health care services to an organism."@en ;
  rdfs:subClassOf obo:OMRSE_00000010 .

obo:IDO_0000610 a rdfs:Class ;
  rdfs:label "immunosuppression"@en ;
  rdfs:comment "A process that attenuates an immune response."@en ;
  rdfs:subClassOf obo:BFO_0000015 .

obo:RO_0002212 a rdf:Property ;
  rdfs:label "negatively regulates"@en ;
  rdfs:comment "p negatively regulates q iff p regulates q, and p decreases the rate or magnitude of execution of q." ;
  rdfs:range <https://w3id.org/linkml/Any> ;
  rdfs:subPropertyOf obo:RO_0002305 , obo:RO_0002211 .

obo:OMIABIS_0000006 a rdfs:Class ;
  rdfs:label "obsolete sample collection or study identifier" ;
  rdfs:subClassOf <http://www.geneontology.org/formats/oboInOwl#ObsoleteClass> .

obo:OMIABIS_0000010 a rdfs:Class ;
  rdfs:label "obsolete biobank organization" ;
  rdfs:subClassOf <http://www.geneontology.org/formats/oboInOwl#ObsoleteClass> .

obo:OBIB_0000601 a rdfs:Class ;
  rdfs:label "clinical history of dementia of unknown cause" ;
  rdfs:comment "A clinical history in which there is a history of dementia with unknown cause  that is not caused by a previous Cerebrovascular Accident (CVA) infection, head trauma or brain tumor)." ;
  rdfs:subClassOf obo:OGMS_0000015 .

obo:OBI_0002432 a rdfs:Class ;
  rdfs:label "history of sex with someone with a history of blood borne infection  exclusion criterion" ;
  rdfs:comment "An exclusion criterion defined  as whether an individual has a history of sex with someone who has been diagnosed or at risk for a blood borne infections disease in a specified time frame, which if met, makes the individual unsuitable for a given task or participation in a given process." ;
  rdfs:subClassOf obo:OBI_0500028 .

obo:OBIB_0000372 a rdfs:Class ;
  rdfs:label "date and time FFPE tissue cassette removed from processor" ;
  rdfs:comment "A data item indicating the date and time when a tissue cassette was removed from a tissue processor as part of a formalin-fixed paraffin-embedded (FFPE) process." ;
  rdfs:subClassOf obo:IAO_0000027 .

obo:OBIB_0000611 a rdfs:Class ;
  rdfs:label "indication of having lived in the United Kingdom during specific time frame" ;
  rdfs:comment "An information content entity in which there is an indication of whether an individual spent a total of three or more months in the United Kingdom, in a specified time frame." ;
  rdfs:subClassOf obo:IAO_0000030 .

obo:OBI_0002412 a rdfs:Class ;
  rdfs:label "premenopausal status" ;
  rdfs:comment "A menopausal status indicating that less than 6 months has passed since the last menstrual period and there has not been prior bilateral oophorectomy and not on estrogen replacement." ;
  rdfs:subClassOf obo:OBI_0002410 .

obo:OBIB_0000673 a rdfs:Class ;
  rdfs:label "diseased state specimen datum"@en ;
  rdfs:comment "A specimen disease state datum item that specifies that the specimen in question consists of a disorder."@en ;
  rdfs:subClassOf obo:OBIB_0000672 .

obo:OBIB_0000723 a rdfs:Class ;
  rdfs:label "specimen measurement specification"@en ;
  rdfs:comment "An directive information entity that states the technical standard measurement set and values that determines if a specimen qualifies for procurement or not."@en ;
  rdfs:subClassOf obo:IAO_0000005 .

obo:OBIB_0000168 a rdfs:Class ;
  rdfs:label "laparoscopic surgical method" ;
  rdfs:comment "A surgical method in which operations are performed far from their location through small incisions (usually 0.5���1.5��cm) elsewhere in the body." ;
  rdfs:subClassOf obo:OBIB_0000165 .

obo:OBI_0600018 a rdfs:Class ;
  rdfs:label "material portioning"@en ;
  rdfs:comment "a material processing in which the input substance is partitioned into a number of portions that are similar in composition."@en ;
  rdfs:subClassOf obo:OBI_0600014 .

obo:PATO_0001710 a rdfs:Class ;
  rdfs:label "3-D extent" ;
  rdfs:comment "A size quality inhering in an bearer by virtue of the bearer's extension in three dimensions." ;
  rdfs:subClassOf obo:PATO_0000117 .

obo:OMRSE_00000033 a rdfs:Class ;
  rdfs:label "aggregate of organizations"@en ;
  rdfs:comment "An object aggregate that is not itself an organization and whose members are only organizations that have some feature in common"@en ;
  rdfs:subClassOf obo:BFO_0000040 .

obo:OBI_0000922 a rdfs:Class ;
  rdfs:label "frozen specimen" ;
  rdfs:comment "A specimen that has been frozen in order to store it." ;
  rdfs:subClassOf obo:OBI_0001472 .

obo:OBIB_0000012 a rdfs:Class ;
  rdfs:label "human subject recuiter role"@en ;
  rdfs:comment "A worker role of recruiting human subjects to partcipate in a clinical investigation in which data about human subject is collected." ;
  rdfs:subClassOf obo:OBI_0000116 .

obo:OMRSE_00000010 a rdfs:Class ;
  rdfs:label "human health care role"@en ;
  rdfs:comment "A role in human social processes that is realized by health care processes such as seeking or providing treatment for disease and injury, diagnosing disease and injury, or undergoing diagnosis. "@en ;
  rdfs:subClassOf obo:OMRSE_00002072 .

obo:OBIB_0000265 a rdfs:Class ;
  rdfs:label "time of blood cell pellet transfer to storage" ;
  rdfs:comment "A data item indicating the time when the blood cell pellet specimen was transferred to storage." ;
  rdfs:subClassOf obo:IAO_0000027 .

obo:FMA_24981 a rdfs:Class ;
  rdfs:label "Left leg" ;
  rdfs:subClassOf obo:UBERON_0000465 .

obo:NCIT_C126538 a rdfs:Class ;
  rdfs:label "Scandinavian" ;
  rdfs:comment "Denotes a person whose ancestry is in the countries of Scandinavia: Denmark, Norway and Sweden. Finland and Iceland are generally included as part of the Scandinavian region." ;
  rdfs:subClassOf obo:OBI_0000181 .

obo:OBIB_0000730 a rdfs:Class ;
  rdfs:label "start of sampling specimens for biobank"@en ;
  rdfs:comment "The process boundary marking the beginning of a sampling of specimens into a biobank."@en ;
  rdfs:subClassOf obo:BFO_0000035 .

obo:OBI_0000011 a rdfs:Class ;
  rdfs:label "planned process"@en ;
  rdfs:comment "A process that realizes a plan which is the concretization of a plan specification."@en ;
  rdfs:subClassOf obo:BFO_0000015 .

obo:OBI_0001931 a rdfs:Class ;
  rdfs:label "scalar value specification" ;
  rdfs:comment "A value specification that consists of two parts: a numeral and a unit label" ;
  rdfs:subClassOf obo:OBI_0001933 .

obo:OBI_0001937 a rdf:Property ;
  rdfs:label "has specified numeric value" ;
  rdfs:comment "A relation between a value specification and a number that quantifies it." ;
  rdfs:range <https://w3id.org/linkml/Any> ;
  rdfs:subPropertyOf obo:OBI_0002135 .

obo:OBIB_0000597 a rdfs:Class ;
  rdfs:label "clinical history of Reye's Syndrome" ;
  rdfs:comment "A clinical history in which there is a history of Reye's Syndrome." ;
  rdfs:subClassOf obo:OGMS_0000015 .

obo:OBI_0002198 a rdfs:Class ;
  rdfs:label "molecular analysis facility organization"@en ;
  rdfs:comment "An organization that provides molecular analysis service." ;
  rdfs:subClassOf obo:OBI_0000245 .

obo:BFO_0000008 a rdfs:Class ;
  rdfs:label "temporal region"@en ;
  rdfs:subClassOf obo:BFO_0000003 .

obo:OBIB_0000000 a rdfs:Class ;
  rdfs:label "biobank description in english"@en ;
  rdfs:comment "A textual entity providing information about a biobank and that is written in English."@en ;
  rdfs:subClassOf obo:IAO_0000300 .

obo:OBIB_0000238 a rdfs:Class ;
  rdfs:label "comment from blood specimen collection" ;
  rdfs:comment "A textual entity that states additional information about the blood specimen or donor that is deemed relevant for the specimen collection process." ;
  rdfs:subClassOf obo:IAO_0000300 .

obo:OBI_0001165 a rdfs:Class ;
  rdfs:label "age since coitus measurement datum"@en ;
  rdfs:comment "An age measurement datum that is the result of the measurement of the age of an organism since coitus, the process of copulation that occurs during the process of sexual reproduction." ;
  rdfs:subClassOf obo:OBI_0001167 .

obo:OBI_0002609 a rdfs:Class ;
  rdfs:label "rectal swab specimen" ;
  rdfs:comment "A specimen that is collected with a swab from the surface of a rectum." ;
  rdfs:subClassOf obo:OBI_0002599 .

obo:OBI_0002510 a rdfs:Class ;
  rdfs:label "synovial fluid specimen" ;
  rdfs:comment "A specimen that is derived from synovial fluid." ;
  rdfs:subClassOf obo:OBI_2000009 .

obo:OBIB_0002004 a rdfs:Class ;
  rdfs:label "surgical cancer treatment"@en ;
  rdfs:comment "A  cancer therapeutic procedure that involves a surgical procedure as a main part." ;
  rdfs:subClassOf obo:NCIT_C16212 .

obo:NCIT_C77811 a rdfs:Class ;
  rdfs:label "Mediterranean" ;
  rdfs:comment "Denotes a person having origins in any of the countries abutting the Mediterranean Sea, principally those of Europe." ;
  rdfs:subClassOf obo:OBI_0000181 .

obo:OBIB_0000227 a rdfs:Class ;
  rdfs:label "nurse anesthetist role" ;
  rdfs:comment "A nurse role borne by a nurse who specializes in the administration of anesthesia." ;
  rdfs:subClassOf obo:OMRSE_00000014 .

obo:OBI_0002535 a rdfs:Class ;
  rdfs:label "esophagus muscularis mucosa specimen" ;
  rdfs:comment "A specimen that is derived from esophagus muscularis mucosa." ;
  rdfs:subClassOf obo:OBI_0001479 .

obo:IAO_0000033 a rdfs:Class ;
  rdfs:label "directive information entity"@en ;
  rdfs:comment "An information content entity whose concretizations indicate to their bearer how to realize them in a process."@en ;
  rdfs:subClassOf obo:IAO_0000030 .

obo:OBIB_0000560 a rdfs:Class ;
  rdfs:label "clinical history of tuberculosis" ;
  rdfs:comment "A clinical history in which there is a history of tuberculosis ." ;
  rdfs:subClassOf obo:OGMS_0000015 .

obo:OBI_0002431 a rdfs:Class ;
  rdfs:label "intravenous drug use exclusion criterion" ;
  rdfs:comment "An exclusion criterion defined as when an individual has a history of intravenous drug abuse for a specific timeframe, which if met, makes the individual unsuitable for a given task or participation in a given process." ;
  rdfs:subClassOf obo:OBI_0500028 .

obo:BFO_0000002 a rdfs:Class ;
  rdfs:label "continuant"@en ;
  rdfs:comment "An entity that exists in full at any time in which it exists at all, persists through time while maintaining its identity and has no temporal parts."@en ;
  rdfs:subClassOf obo:BFO_0000001 .

obo:OBIB_0000504 a rdfs:Class ;
  rdfs:label "date of chemotherapy prior to surgery" ;
  rdfs:comment "A data item that reports the calendar date when chemotherapy was received prior to surgery." ;
  rdfs:subClassOf obo:IAO_0000027 .

obo:UBERON_0002084 a rdfs:Class ;
  rdfs:label "heart left ventricle" ;
  rdfs:comment "A cardiac ventricle that is in the left side of the heart." ;
  rdfs:subClassOf obo:UBERON_0000064 .

obo:OBI_0002662 a rdfs:Class ;
  rdfs:label "bone marrow biopsy" ;
  rdfs:comment "A biopsy where a small amount of bone and a small amount of fluid and bone marrow are collected." ;
  rdfs:subClassOf obo:OBI_0002650 .

obo:OBI_0000181 a rdfs:Class ;
  rdfs:label "population"@en ;
  rdfs:comment "a population is a collection of individuals from the same taxonomic class living, counted or sampled at a particular site or in a particular area"@en ;
  rdfs:subClassOf obo:BFO_0000040 .

obo:OBIB_0000452 a rdfs:Class ;
  rdfs:label "activity related to a particular specimen donor was stopped because not enough blood collected" ;
  rdfs:comment "An activity related to a particular specimen donor was stopped that is because there was not enough blood collected." ;
  rdfs:subClassOf obo:OBIB_0000451 .

obo:UBERON_0000007 a rdfs:Class ;
  rdfs:label "pituitary gland" ;
  rdfs:comment "The pituitary gland is an endocrine gland that secretes hormones that regulate many other glands [GO]. An endocrine gland located ventral to the diencephalon and derived from mixed neuroectodermal and non neuroectodermal origin [ZFIN]." ;
  rdfs:subClassOf obo:UBERON_0000465 .

obo:OBI_0002604 a rdfs:Class ;
  rdfs:label "breast swab specimen" ;
  rdfs:comment "A specimen that is collected with a swab from the surface of a breast." ;
  rdfs:subClassOf obo:OBI_0002599 .

obo:OBI_0000953 a rdfs:Class ;
  rdfs:label "processed specimen" ;
  rdfs:comment "A specimen that has been intentionally physically modified." ;
  rdfs:subClassOf obo:OBI_0000047 , obo:OBI_0100051 .

obo:OBIB_0000140 a rdfs:Class ;
  rdfs:label "platelet volume administered intraoperatively" ;
  rdfs:comment "A measurement datum of the volume of platelets administered during surgery measured." ;
  rdfs:subClassOf obo:IAO_0000109 .

obo:FMA_83876 a rdfs:Class ;
  rdfs:label "Right hemisphere of cerebellum" ;
  rdfs:subClassOf obo:UBERON_0000064 .

obo:OBIB_0000369 a rdfs:Class ;
  rdfs:label "date and time FFPE tissue cassette placed in processor" ;
  rdfs:comment "A data item indicating the date and time when a tissue cassette was placed in a tissue processor as part of a formalin-fixed paraffin-embedded (FFPE) process." ;
  rdfs:subClassOf obo:IAO_0000027 .

obo:NCIT_C16171 a rdfs:Class ;
  rdfs:label "Prior Chemotherapy" ;
  rdfs:comment "Previous chemotherapy administered as treatment for this cancer." ;
  rdfs:subClassOf obo:OGMS_0000090 .

obo:OBIB_0000561 a rdfs:Class ;
  rdfs:label "clinical history of meningitis at death" ;
  rdfs:comment "A  clinical history in which there was active meningitis at death." ;
  rdfs:subClassOf obo:OGMS_0000015 .

obo:OBIB_0000688 a rdfs:Class ;
  rdfs:label "physiological measurement data"@en ;
  rdfs:comment "A measurement datum that contains the assessment information about the functioning of a major organ system, the extent of disease or disability,as well as the provision and/or response to therapeutic interventions."@en ;
  rdfs:subClassOf obo:IAO_0000027 .

obo:OBI_0002611 a rdfs:Class ;
  rdfs:label "vagina swab specimen" ;
  rdfs:comment "A specimen that is collected with a swab from the surface of a vagina." ;
  rdfs:subClassOf obo:OBI_0002599 .

obo:OMIABIS_0000031 a rdfs:Class ;
  rdfs:label "obsolete intra-settlement specification part of address" ;
  rdfs:subClassOf <http://www.geneontology.org/formats/oboInOwl#ObsoleteClass> .

obo:OBI_0002149 a rdfs:Class ;
  rdfs:label "core HBV antibody assay" ;
  rdfs:comment "An antigen specific antibodies assay that is meant to detect antibodies that bind to hepatitis B virus (HBV) core antigens." ;
  rdfs:subClassOf obo:OBI_0002145 .

obo:OBI_0002150 a rdfs:Class ;
  rdfs:label "core HBV IgM antibody assay" ;
  rdfs:comment "An antigen specific antibodies assay that is meant to detectimmunoglobulin M (IgM) antibodies that bind to hepatitis B virus (HBV) core antigens." ;
  rdfs:subClassOf obo:OBI_0002145 .

obo:UBERON_0001968 a rdfs:Class ;
  rdfs:label "semen" ;
  rdfs:comment "Organism substance that is composed of sperm cells suspended in seminal fluid." ;
  rdfs:subClassOf obo:UBERON_0000463 .

obo:OBIB_0000135 a rdfs:Class ;
  rdfs:label "second temperature recorded in operating room of specimen donor" ;
  rdfs:comment "A  time stamped measurement datum that is the second temperature recorded in the operating room of the specimen donor." ;
  rdfs:subClassOf obo:IAO_0000582 .

obo:OBIB_0000071 a rdfs:Class ;
  rdfs:label "specimen transport SOP" ;
  rdfs:comment "A standard operating procedure for the transportation of specimens." ;
  rdfs:subClassOf obo:OBIB_0000070 .

obo:UBERON_0001234 a rdfs:Class ;
  rdfs:label "left adrenal gland" ;
  rdfs:comment "An adrenal gland that is in the left side of the abdomen." ;
  rdfs:subClassOf obo:UBERON_0002369 .

obo:OBIB_0000329 a rdfs:Class ;
  rdfs:label "comment on deviations from microtome daily maintenance SOP" ;
  rdfs:comment "A textual entity that states information about deviations from a microtome daily maintenance standard operating procedure." ;
  rdfs:subClassOf obo:IAO_0000300 .

obo:OBIB_0000474 a rdfs:Class ;
  rdfs:label "identification number of a protocol at a particular site" ;
  rdfs:comment "An centrally registered identifier symbol assigned by an Institutional Review Board (IRB) that identifies a particular protocol at a given site." ;
  rdfs:subClassOf obo:IAO_0000577 .

obo:OBI_0002203 a rdfs:Class ;
  rdfs:label "pTX" ;
  rdfs:comment "A cannot be assessed determination for pathologic primary tumor staging." ;
  rdfs:subClassOf obo:OBI_0002200 .

obo:OBI_0002434 a rdfs:Class ;
  rdfs:label "HIV exclusion criterion" ;
  rdfs:comment "An exclusion criterion defined  as whether an individual has a history of repeatedly reactive screening assays for HIV-1 or HIV-2 antibody regardless of the results of supplemental assays, which if met, makes the individual unsuitable for a given task or participation in a given process." ;
  rdfs:subClassOf obo:OBI_0500028 .

obo:OBI_0002417 a rdfs:Class ;
  rdfs:label "exposure to asbestos history" ;
  rdfs:comment "An exposure to environmental and workplace carcinogens history where the carcinogen is asbestos." ;
  rdfs:subClassOf obo:OBI_0002415 .

obo:CHEBI_6754 a rdfs:Class ;
  rdfs:label "pethidine" ;
  rdfs:comment "A piperidinecarboxylate ester that is piperidine which is substituted by a methyl group at position 1 and by phenyl and ethoxycarbonyl groups at position 4. It is an analgesic which is used for the treatment of moderate to severe pain, including postoperative pain and labour pain." ;
  rdfs:subClassOf obo:CHEBI_23367 .

obo:OBIB_0000358 a rdfs:Class ;
  rdfs:label "pathology research center" ;
  rdfs:comment "A laboratory that performs a rigorous review of images of tissue specimens by a group of senior pathologists not involved in the specimen collection typically to evaluate and characterize the tissue (e.g., % necrosis)." ;
  rdfs:subClassOf <http://vivoweb.org/ontology/core#Laboratory> .

obo:OBIB_0000113 a rdfs:Class ;
  rdfs:label "administration of insulin during surgery" ;
  rdfs:comment "A planned process to administer insulin during a surgical procedure." ;
  rdfs:subClassOf obo:OBI_0000011 .

obo:OBI_0002509 a rdfs:Class ;
  rdfs:label "sweat specimen" ;
  rdfs:comment "A specimen that is derived from sweat." ;
  rdfs:subClassOf obo:OBI_2000009 .

obo:OBIB_0000575 a rdfs:Class ;
  rdfs:label "clinical history of inability to have Human Immunodeficiency Virus testing due to hemodilution" ;
  rdfs:comment "A clinical history in which there is a history of the donor not being able to be tested for Human Immunodeficiency Virus (HIV) because of hemodilution." ;
  rdfs:subClassOf obo:OGMS_0000015 .

obo:OBI_0000437 a rdfs:Class ;
  rdfs:label "analyte measurement objective"@en ;
  rdfs:comment "an assay objective to determine the presence or concentration of an analyte in the evaluant"@en ;
  rdfs:subClassOf obo:OBI_0000441 .

obo:OBIB_0000216 a rdfs:Class ;
  rdfs:label "fixative product manufacturer" ;
  rdfs:comment "A manufacturer that produces fixatives used in specimen collection." ;
  rdfs:subClassOf obo:OBI_0000835 .

obo:OBIB_0000712 a rdfs:Class ;
  rdfs:label "comment from tissue procurement"@en ;
  rdfs:comment "A textual entity that states additional information about the specimen or donor that is deemed relevant for the specimen collection process."@en ;
  rdfs:subClassOf obo:IAO_0000300 .

obo:OBIB_0000318 a rdfs:Class ;
  rdfs:label "name of specimen slide preparation technician" ;
  rdfs:comment "A personal name that designates the person who performed a specimen slide preparation." ;
  rdfs:subClassOf obo:IAO_0020015 .

obo:UBERON_0000002 a rdfs:Class ;
  rdfs:label "uterine cervix" ;
  rdfs:comment "Lower, narrow portion of the uterus where it joins with the top end of the vagina." ;
  rdfs:subClassOf obo:UBERON_0000465 .

obo:OBIB_0000622 a rdfs:Class ;
  rdfs:label "ISO 3166-1 alpha-2 code for sample collection or study contact"@en ;
  rdfs:comment "The ISO 3166-1 alpha-2 code that is part of the sample collection or study contact's postal address."@en ;
  rdfs:subClassOf obo:OBIB_0000620 .

obo:OBIB_0000303 a rdfs:Class ;
  rdfs:label "FFPE clearing agent temperature" ;
  rdfs:comment "A scalar measurement datum that is the output of a temperature measurement assay performed on a specimen in clearing agent in a formalin-fixed paraffin-embedded (FFPE) process." ;
  rdfs:subClassOf obo:IAO_0000032 .

obo:OBI_0100016 a rdfs:Class ;
  rdfs:label "blood plasma specimen"@en ;
  rdfs:comment "a material entity which corresponds to the liquid component of blood, in which the blood cells are suspended."@en ;
  rdfs:subClassOf obo:OBI_0000953 .

obo:OBIB_0000510 a rdfs:Class ;
  rdfs:label "greater than moderate alcohol consumption history" ;
  rdfs:comment "An Alcohol Use History in which alcohol consumption was more than 2 drinks per day for men and more than 1 drink per day for women." ;
  rdfs:subClassOf obo:NCIT_C81229 .

obo:UBERON_0002167 a rdfs:Class ;
  rdfs:label "right lung" ;
  rdfs:comment "Lung which consists of the right upper lobe, middle lobe and right lower lobe.[FMA]." ;
  rdfs:subClassOf obo:UBERON_0002048 .

obo:FMA_43899 a rdfs:Class ;
  rdfs:label "Left posterior tibial artery" ;
  rdfs:subClassOf obo:UBERON_0007610 .

obo:OMIABIS_0000001 a rdfs:Class ;
  rdfs:label "obsolete human biobank" ;
  rdfs:subClassOf <http://www.geneontology.org/formats/oboInOwl#ObsoleteClass> .

obo:IAO_0000064 a rdfs:Class ;
  rdfs:label "algorithm"@en ;
  rdfs:comment "A plan specification which describes the inputs and output of mathematical functions as well as workflow of execution for achieving an predefined objective. Algorithms are realized usually by means of implementation as computer programs for execution by automata."@en ;
  rdfs:subClassOf obo:IAO_0000104 .

obo:OBIB_0000485 a rdfs:Class ;
  rdfs:label "age of specimen donor at time that authorization from legally authorized representative was obtained" ;
  rdfs:comment "An age measurement datum that indicates the age of the specimen donor at the time that authorization from their legally authorized representative was obtained." ;
  rdfs:subClassOf obo:OBI_0001167 .

obo:DRON_00015464 a rdfs:Class ;
  rdfs:label "Paraffin" ;
  rdfs:subClassOf obo:OBI_0000047 .

obo:UBERON_0000310 a rdfs:Class ;
  rdfs:label "breast" ;
  rdfs:comment "The upper ventral region of the torso of an organism." ;
  rdfs:subClassOf obo:UBERON_0000465 .

obo:OBIB_0000081 a rdfs:Class ;
  rdfs:label "first tissue removed time" ;
  rdfs:comment "A time of surgical removal of specimen for the first removal of tissue from a donor." ;
  rdfs:subClassOf obo:OBIB_0000725 .

obo:OBIB_0000034 a rdfs:Class ;
  rdfs:label "adding specimen into a container"@en ;
  rdfs:comment "An adding a material entity into a target process where a collected specimen is added to a specimen container. (note, not used for other specimen process that produce new specimens)" ;
  rdfs:subClassOf obo:OBI_0000274 .

obo:OBIB_0000383 a rdfs:Class ;
  rdfs:label "specimen was processed in accordance with the FFPE SOP including <1 hour delay to fixation and 23 hour time in fixative" ;
  rdfs:comment "A specimen was processed in accordance with the specified SOP where the specified SOP is for a formalin-fixed paraffin-embedded (FFPE) process and includes less than 1 hour delay in fixation and 23 hour time in fixative." ;
  rdfs:subClassOf obo:OBIB_0000259 .

obo:OBIB_0000515 a rdfs:Class ;
  rdfs:label "current reformed smoker for less than 15 years history" ;
  rdfs:comment "A Smoking History in which there is no current smoking and has not been smoking for less than 15 years." ;
  rdfs:subClassOf obo:NCIT_C29719 .

obo:OBIB_0000274 a rdfs:Class ;
  rdfs:label "name of person responsible for specimen transport" ;
  rdfs:comment "A personal name that designates the person who is responsible for the transport of a specimen to another organization." ;
  rdfs:subClassOf obo:IAO_0020015 .

obo:OBIB_0000521 a rdfs:Class ;
  rdfs:label "pill-based hormonal birth control method" ;
  rdfs:comment "A birth control method that involves the use of an oral hormone-based contraceptive typically taken as a pill." ;
  rdfs:subClassOf obo:NCIT_C106501 .

obo:OBIB_0000677 a rdfs:Class ;
  rdfs:label "age interval information"@en ;
  rdfs:comment "An information content entity that is about a data set that has age information and specifies the range of age information in that data set."@en ;
  rdfs:subClassOf obo:IAO_0000030 .

obo:OBI_0002745 a rdfs:Class ;
  rdfs:label "vacuum-assisted biopsy" ;
  rdfs:comment "A biopsy performed with a needle augmented with a vacuum device." ;
  rdfs:subClassOf obo:OBI_0002654 .

obo:OBIB_0000701 a rdfs:Class ;
  rdfs:label "survey plan specification"@en ;
  rdfs:comment "A plan specification that is realized by  process of gathering information (e.g. by asking questions)."@en ;
  rdfs:subClassOf obo:IAO_0000104 .

obo:OBIB_0000398 a rdfs:Class ;
  rdfs:label "percentage of necrotic tumor slide specimen by surface area" ;
  rdfs:comment "A data item that is the result of determining the percentage of a tumor slide specimen that is necrotic based on surface area." ;
  rdfs:subClassOf obo:IAO_0000027 .

obo:OMIABIS_0001027 a rdfs:Class ;
  rdfs:label "obsolete sample medical record" ;
  rdfs:subClassOf <http://www.geneontology.org/formats/oboInOwl#ObsoleteClass> .

obo:OBI_0002525 a rdfs:Class ;
  rdfs:label "tibial artery specimen" ;
  rdfs:comment "A specimen that is derived from tibial artery." ;
  rdfs:subClassOf obo:OBI_0001479 .

obo:OBI_0000397 a rdfs:Class ;
  rdfs:label "image acquisition function"@en ;
  rdfs:comment "An image acquisition function is a function to acquire an image of a material"@en ;
  rdfs:subClassOf obo:OBI_0000453 .

obo:OBIB_0000694 a rdfs:Class ;
  rdfs:label "cross sectional study design"@en ;
  rdfs:comment "A study design in which all participants or a representative subset of participants are examined at only a single time for characteristics of a interest (e.g. a specific disease)."@en ;
  rdfs:subClassOf obo:OBI_0500000 .

obo:IAO_0000429 a rdfs:Class ;
  rdfs:label "email address"@en ;
  rdfs:subClassOf obo:IAO_0000030 .

obo:OBI_2000001 a rdfs:Class ;
  rdfs:label "urethra specimen" ;
  rdfs:comment "A specimen that is derived from some urethra" ;
  rdfs:subClassOf obo:OBI_0001479 .

obo:OBI_2000014 a rdfs:Class ;
  rdfs:label "venous blood specimen" ;
  rdfs:comment "A specimen that is derived from some venous blood" ;
  rdfs:subClassOf obo:OBI_2000009 .

obo:OBIB_0000249 a rdfs:Class ;
  rdfs:label "time of blood processing" ;
  rdfs:comment "A data item indicating the time when a blood specimen was processed." ;
  rdfs:subClassOf obo:IAO_0000027 .

obo:OBIB_0000254 a rdfs:Class ;
  rdfs:label "time of blood plasma specimen placement on dry ice" ;
  rdfs:comment "A data item indicating the time when a blood plasma specimen was placed on dry ice." ;
  rdfs:subClassOf obo:IAO_0000027 .

obo:OBIB_0000142 a rdfs:Class ;
  rdfs:label "specimen donor intraoperative blood loss volume measurement datum" ;
  rdfs:comment "A measurement datum of the volume of intraoperative blood loss from the specimen donor." ;
  rdfs:subClassOf obo:IAO_0000109 .

obo:CL_0000578 a rdfs:Class ;
  rdfs:label "experimentally modified cell in vitro" ;
  rdfs:comment "A cell in vitro that has undergone physical changes as a consequence of a deliberate and specific experimental procedure." ;
  rdfs:subClassOf obo:CL_0001034 .

obo:UBERON_0002113 a rdfs:Class ;
  rdfs:label "kidney" ;
  rdfs:comment "A paired organ of the urinary tract which has the production of urine as its primary function." ;
  rdfs:subClassOf obo:UBERON_0000465 .

obo:OBIB_0000662 a rdfs:Class ;
  rdfs:label "flash frozen specimen"@en ;
  rdfs:comment "A frozen specimen that has been instantly/quickly frozen by subjecting the specimen to cryogenic temperatures, or in direct contact with liquid nitrogen at -320.8F 0r -196C."@en ;
  rdfs:subClassOf obo:OBI_0000922 .

obo:OGMS_0000031 a rdfs:Class ;
  rdfs:label "disease" ;
  rdfs:comment "A disposition (i) to undergo pathological processes that (ii) exists in an organism because of one or more disorders in that organism."@en ;
  rdfs:subClassOf obo:BFO_0000016 .

obo:OBI_1110087 a rdfs:Class ;
  rdfs:label "donor"@en ;
  rdfs:comment "A role which inheres in an organism or part thereof from which any part including cell, organ or tissue is removed with the intention that the donated part will be placed into another organism and/or cultured in vitro."@en ;
  rdfs:subClassOf obo:BFO_0000023 .

obo:OBIB_0000056 a rdfs:Class ;
  rdfs:label "tobacco"@en ;
  rdfs:comment "A Eukaryota that is within the genus Nicotiana of the Solanaceae (nightshade) family." ;
  rdfs:subClassOf obo:NCBITaxon_2759 .

obo:OBIB_0000183 a rdfs:Class ;
  rdfs:label "open surgical method" ;
  rdfs:comment "A surgical method in which an incision is made using a scalpel. Open surgery is the traditional type of surgery." ;
  rdfs:subClassOf obo:OBIB_0000165 .

obo:OBIB_0000703 a rdfs:Class ;
  rdfs:label "sample medical record"@en ;
  rdfs:comment "A medical record of a specimen donor."@en ;
  rdfs:subClassOf obo:OBIB_0000702 .

obo:OBI_0002194 a rdfs:Class ;
  rdfs:label "Microm Ergostar HM200" ;
  rdfs:comment "A microtome that is manufactured by Microm and uses a vertical cutting stroke common to all rotary microtomes engaged by a horizontal sliding movement. An operating arm replaces the handwheel and is attached to both sides of the instrument for greater convenience to permit control of sectioning from the left or right." ;
  rdfs:subClassOf obo:OBI_0400168 .

obo:CL_0000232 a rdfs:Class ;
  rdfs:label "erythrocyte" ;
  rdfs:comment "A red blood cell. In mammals, mature erythrocytes are biconcave disks containing hemoglobin whose function is to transport oxygen." ;
  rdfs:subClassOf obo:CL_0000000 .

obo:OBIB_0000252 a rdfs:Class ;
  rdfs:label "blood plasma specimen barcode" ;
  rdfs:comment "A specimen barcode that is associated with a blood plasma specimen." ;
  rdfs:subClassOf obo:FLU_0001019 .

obo:OBI_0100026 a rdfs:Class ;
  rdfs:label "organism"@en ;
  rdfs:comment "A material entity that is an individual living system, such as animal, plant, bacteria or virus, that is capable of replicating or reproducing, growth and maintenance in the right environment. An organism may be unicellular or made up, like humans, of many billions of cells divided into specialized tissues and organs."@en ;
  rdfs:subClassOf obo:BFO_0000040 .

obo:OBI_0002503 a rdfs:Class ;
  rdfs:label "feces specimen" ;
  rdfs:comment "A specimen that is derived from feces." ;
  rdfs:subClassOf obo:OBI_0001479 .

obo:OBIB_0000376 a rdfs:Class ;
  rdfs:label "FFPE freezing protocol" ;
  rdfs:comment "A protocol for the freezing step of a formalin-fixed paraffin-embedded (FFPE) process." ;
  rdfs:subClassOf obo:OBI_0000272 .

obo:OBI_0000441 a rdfs:Class ;
  rdfs:label "assay objective"@en ;
  rdfs:comment "an objective specification to determine a specified type of information about an evaluated entity (the material entity bearing evaluant role)"@en ;
  rdfs:subClassOf obo:IAO_0000005 .

obo:OBI_0001867 a rdfs:Class ;
  rdfs:label "establishing cell line" ;
  rdfs:comment "a process whereby a new type of cell line is created, either through passaging of a primary cell culture to relative genetic stability and compositional homogeneity, or through some experimental modification of an existing cell line to produce a new line with novel characteristics  (e.g. immortalization or some other stable genetic modification, or selection of some defined subset)." ;
  rdfs:subClassOf obo:OBI_0600036 .

obo:UBERON_0002048 a rdfs:Class ;
  rdfs:label "lung" ;
  rdfs:comment "Respiration organ that develops as an outpocketing of the esophagus." ;
  rdfs:subClassOf obo:UBERON_0000465 .

obo:OBI_0000950 a rdfs:Class ;
  rdfs:label "paraffin specimen" ;
  rdfs:comment "a specimen that is output of a paraffin storage process in which specimen is embedded in paraffin" ;
  rdfs:subClassOf obo:OBI_0001472 .

obo:OBIB_0000115 a rdfs:Class ;
  rdfs:label "administration of antimicrobial agent during surgery" ;
  rdfs:comment "A planned process to administer antimicrobial agent(s) during a surgical procedure." ;
  rdfs:subClassOf obo:OBI_0000011 .

obo:OBI_0001755 a rdfs:Class ;
  rdfs:label "selection criterion"@en ;
  rdfs:comment "A directive information entity which defines and states a principle of standard by which selection process may take place."@en ;
  rdfs:subClassOf obo:IAO_0000033 .

obo:OBIB_0000164 a rdfs:Class ;
  rdfs:label "right salpingo-oophorectomy" ;
  rdfs:comment "A surgical procedure to remove the right ovary and right fallopian tube." ;
  rdfs:subClassOf obo:OBIB_0000716 .

obo:OBIB_0000630 a rdfs:Class ;
  rdfs:label "department"@en ;
  rdfs:comment "An organization with a specific responsibility that is a part of a larger organization with a specific responsibility."@en ;
  rdfs:subClassOf obo:OBI_0000245 .

obo:OBI_0002420 a rdfs:Class ;
  rdfs:label "exposure to silica history" ;
  rdfs:comment "An exposure to environmental and workplace carcinogens history where the carcinogen is silica." ;
  rdfs:subClassOf obo:OBI_0002415 .

obo:OMIABIS_0000047 a rdfs:Class ;
  rdfs:label "obsolete biobank identifier with ISO 3166-1 alpha-2 code and CTEP organization identifier" ;
  rdfs:subClassOf <http://www.geneontology.org/formats/oboInOwl#ObsoleteClass> .

obo:OBIB_0000104 a rdfs:Class ;
  rdfs:label "preoperative intravenous administration of antacid" ;
  rdfs:comment "A planned process to administer antacid intravenously prior to surgery  in order to relieve and reduce the symptoms of ulcers in the stomach and upper small intestine." ;
  rdfs:subClassOf obo:OBI_0000011 .

obo:OMIABIS_0000036 a rdfs:Class ;
  rdfs:label "obsolete sample collection or study aim description" ;
  rdfs:subClassOf <http://www.geneontology.org/formats/oboInOwl#ObsoleteClass> .

obo:OBI_2000004 a rdfs:Class ;
  rdfs:label "eye specimen" ;
  rdfs:comment "A specimen that is derived from some eye" ;
  rdfs:subClassOf obo:OBI_0001479 .

obo:CHEBI_35482 a rdfs:Class ;
  rdfs:label "opioid analgesic" ;
  rdfs:comment "A narcotic or opioid substance, synthetic or semisynthetic agent producing profound analgesia, drowsiness, and changes in mood." ;
  rdfs:subClassOf obo:OGMS_0000148 .

obo:OBIB_0000325 a rdfs:Class ;
  rdfs:label "uncharged glass slide indicator" ;
  rdfs:comment "An information content entity that indicates that a glass slide has not been positively charged." ;
  rdfs:subClassOf obo:IAO_0000030 .

obo:CHEBI_119915 a rdfs:Class ;
  rdfs:label "fentanyl" ;
  rdfs:comment "A monocarboxylic acid amide resulting from the formal condensation of the aryl amino group of N-phenyl-1-(2-phenylethyl)piperidin-4-amine with propanoic acid." ;
  rdfs:subClassOf obo:CHEBI_23367 .

obo:UBERON_0007311 a rdfs:Class ;
  rdfs:label "sputum" ;
  rdfs:comment "Matter ejected from the lungs, bronchi, and trachea, through the mouth." ;
  rdfs:subClassOf obo:UBERON_0000463 .

obo:UBERON_0002371 a rdfs:Class ;
  rdfs:label "bone marrow" ;
  rdfs:comment "The soft tissue that fills the cavities of bones." ;
  rdfs:subClassOf obo:UBERON_0000479 .

obo:OMIABIS_0001033 a rdfs:Class ;
  rdfs:label "obsolete sample collection data entry" ;
  rdfs:subClassOf <http://www.geneontology.org/formats/oboInOwl#ObsoleteClass> .

obo:PR_000000001 a rdfs:Class ;
  rdfs:label "protein" ;
  rdfs:comment "An amino acid chain that is produced de novo by ribosome-mediated translation of a genetically-encoded mRNA, and any derivatives thereof." ;
  rdfs:subClassOf obo:CHEBI_23367 .

obo:OBI_0002392 a rdfs:Class ;
  rdfs:label "exposure to second hand smoke in current household" ;
  rdfs:comment "An exposure to second hand smoke in person's current household." ;
  rdfs:subClassOf obo:OBI_0002390 .

obo:OBIB_0000627 a rdfs:Class ;
  rdfs:label "name of biobank contact person"@en ;
  rdfs:comment "A personal name that designates the person acting as contact for a biobank."@en ;
  rdfs:subClassOf obo:IAO_0020015 .

obo:CL_0000001 a rdfs:Class ;
  rdfs:label "primary cultured cell" ;
  rdfs:comment "A cultured cell that is freshly isolated from a organismal source, or derives in culture from such a cell prior to the culture being passaged." ;
  rdfs:subClassOf obo:CL_0000010 .

obo:OBIB_0000727 a rdfs:Class ;
  rdfs:label "hosting biobank"@en ;
  rdfs:comment "A biobank that collects and stores specimen during specimen collection primarily for the purposes of some study."@en ;
  rdfs:subClassOf obo:OBIB_0000616 .

obo:OBIB_0000608 a rdfs:Class ;
  rdfs:label "indication of a tattoo from unregulated tattoo parlor" ;
  rdfs:comment "An information content entity in which there is an indication of whether an individual had a tattoo done in a state that does not regulate tattoo parlors, in the recent past." ;
  rdfs:subClassOf obo:IAO_0000030 .

obo:UBERON_0000990 a rdfs:Class ;
  rdfs:label "reproductive system" ;
  rdfs:comment "Anatomical system that has as its parts the organs concerned with reproduction." ;
  rdfs:subClassOf obo:UBERON_0000465 .

obo:OBIB_0000565 a rdfs:Class ;
  rdfs:label "clinical history of unexplained seizures" ;
  rdfs:comment "A clinical history in which there is a history of unexplained seizures." ;
  rdfs:subClassOf obo:OGMS_0000015 .

obo:OBIB_0000153 a rdfs:Class ;
  rdfs:label "time specimen left operating room" ;
  rdfs:comment "A data item indicating the time at which the surgical specimen left the operating for delivery to the pathology gross room." ;
  rdfs:subClassOf obo:IAO_0000027 .

obo:OBI_0000274 a rdfs:Class ;
  rdfs:label "adding a material entity into a target"@en ;
  rdfs:comment "is a process with the objective to place a material entity bearing the 'material to be added role' into a material bearing the 'target of material addition role'."@en ;
  rdfs:subClassOf obo:OBI_0000652 .

obo:OBIB_0000263 a rdfs:Class ;
  rdfs:label "cell pellet specimen barcode" ;
  rdfs:comment "A specimen barcode that is associated with a cell pellet specimen." ;
  rdfs:subClassOf obo:FLU_0001019 .

obo:OBI_0000671 a rdfs:Class ;
  rdfs:label "sample from organism" ;
  rdfs:comment "a material obtained from an organism in order to be a representative of the whole" ;
  rdfs:subClassOf obo:OBI_0000747 , obo:OBI_0001479 .

obo:OBIB_0000336 a rdfs:Class ;
  rdfs:label "oven temperature during FFPE tissue section H&E staining" ;
  rdfs:comment "A scalar measurement datum that is the output of a temperature measurement assay performed on a oven during a formalin-fixed paraffin-embedded (FFPE) tissue section hematoxylin and eosin (H&E) staining." ;
  rdfs:subClassOf obo:IAO_0000032 .

obo:OBI_0002408 a rdfs:Class ;
  rdfs:label "patch delivery form for hormonal replacement therapy" ;
  rdfs:comment "A delivery form for hormonal replacement therapy that is a patch for transdermal administration." ;
  rdfs:subClassOf obo:OBI_0002406 .

obo:OBIB_0000463 a rdfs:Class ;
  rdfs:label "research authorization for post mortem specimen donation not obtained due to religious reasons" ;
  rdfs:comment "A research authorization documentation for post mortem specimen donation in which the reason authorization was not obtained was due to due to religious reasons." ;
  rdfs:subClassOf obo:OBIB_0000459 .

obo:IAO_0000101 a rdfs:Class ;
  rdfs:label "image"@en ;
  rdfs:comment "An image is an affine projection to a two dimensional surface, of measurements of some quality of an entity or entities repeated at regular intervals across a spatial range, where the measurements are represented as color and luminosity on the projected on surface."@en ;
  rdfs:subClassOf obo:IAO_0000308 .

obo:OMIABIS_0001049 a rdfs:Class ;
  rdfs:label "obsolete time of specimen freezing" ;
  rdfs:subClassOf <http://www.geneontology.org/formats/oboInOwl#ObsoleteClass> .

obo:OBIB_0000060 a rdfs:Class ;
  rdfs:label "time in fixative measurement" ;
  rdfs:comment "A time measurement datum that states the duration during which a specimen was submerged in fixative." ;
  rdfs:subClassOf obo:IAO_0000416 .

obo:OMIABIS_0001044 a rdfs:Class ;
  rdfs:label "obsolete specimen surgical removal" ;
  rdfs:subClassOf <http://www.geneontology.org/formats/oboInOwl#ObsoleteClass> .

obo:OBI_0002375 a rdfs:Class ;
  rdfs:label "daughter clinical history of cancer" ;
  rdfs:comment "A clinical history in which there is a diagnosis of cancer in a person's female child." ;
  rdfs:subClassOf obo:OBI_0002372 .

obo:OBI_0000571 a rdfs:Class ;
  rdfs:label "manufacturer role" ;
  rdfs:comment "Manufacturer role is a role which inheres in a person or organization and which is realized by a manufacturing process." ;
  rdfs:subClassOf obo:OMRSE_00000048 .

obo:OBI_0002560 a rdfs:Class ;
  rdfs:label "family status inclusion criterion"@en ;
  rdfs:comment "An inclusion criterion that defines and states one or more family statuses, which, if met, makes a human being suitable for a given task or participation in a given process."@en ;
  rdfs:subClassOf obo:OBI_0500027 .

obo:HANCESTRO_0014 a rdfs:Class ;
  rdfs:label "Hispanic or Latin American" ;
  rdfs:comment """Includes individuals who either self-report or are described by authors as Hispanic, Latino, Latin American or one of the sub-populations
from this region. This category includes individuals with known admixture of primarily European, African and Native American ancestries, though some may have also a degree of Asian (e.g. Peru). We also note that the levels of admixture vary depending on the country, with Caribbean countries carrying higher levels of African admixture when compared to South American countries, for example. This category also includes individuals who genetically cluster with reference populations from this region, for example 1000 Genomes and/or HapMap CLM, MXL, PEL and PUR populations""" ;
  rdfs:subClassOf obo:HANCESTRO_0004 .

obo:OBIB_0000109 a rdfs:Class ;
  rdfs:label "intravenous administration of opioid analgesic" ;
  rdfs:comment "A planned process to administer opioid analgesics intravenously in order to induce total or partial loss of sensation especially tactile sensation and pain." ;
  rdfs:subClassOf obo:OBI_0000011 .

obo:OBI_0002200 a rdfs:Class ;
  rdfs:label "cannot be assessed determination" ;
  rdfs:comment "A reason for lack of data item that is the negative output of a determination if assay will provide reliable results." ;
  rdfs:subClassOf obo:OBI_0002199 .

obo:OBI_0002381 a rdfs:Class ;
  rdfs:label "grandmother clinical history of cancer" ;
  rdfs:comment "A clinical history in which there is a diagnosis of cancer in a female parent of a parent." ;
  rdfs:subClassOf obo:OBI_0002372 .

obo:HANCESTRO_0487 a rdfs:Class ;
  rdfs:label "Indian"@en ;
  rdfs:subClassOf obo:HANCESTRO_0008 .

obo:UBERON_0022276 a rdfs:Class ;
  rdfs:label "splenic flexure of colon" ;
  rdfs:comment "The splenic (or left colic) flexure is a sharp bend between the transverse and the descending colon in the left upper quadrant of humans. The left colic flexure is near the spleen, and hence called the splenic flexure. There are two colic flexures in the transverse colon &mdash; the other being the hepatic flexure in the right upper quadrant." ;
  rdfs:subClassOf obo:UBERON_0000064 .

obo:OBI_0302893 a rdfs:Class ;
  rdfs:label "storage"@en ;
  rdfs:comment "A maintenance process by which material entities that are not actively metabolizing are placed in well identified location and possibly under controlled environment in ad-hoc devices/structures in order to preserve and protect them from decay/alteration and maintain availability"@en ;
  rdfs:subClassOf obo:OBI_0000838 .

obo:OBI_0000014 a rdfs:Class ;
  rdfs:label "regulator role"@en ;
  rdfs:comment "a regulatory role involved with making and/or enforcing relevant legislation and governmental orders"@en ;
  rdfs:subClassOf obo:OBI_0000017 .

obo:CHEBI_16670 a rdfs:Class ;
  rdfs:label "peptide" ;
  rdfs:comment "Amide derived from two or more amino carboxylic acid molecules (the same or different) by formation of a covalent bond from the carbonyl carbon of one to the nitrogen atom of another with formal loss of water. The term is usually applied to structures formed from alpha-amino acids, but it includes those derived from any amino carboxylic acid. X = OH, OR, NH2, NHR, etc." ;
  rdfs:subClassOf obo:CHEBI_33839 .

obo:OMIABIS_0000018 a rdfs:Class ;
  rdfs:label "obsolete department of biobank contact" ;
  rdfs:subClassOf <http://www.geneontology.org/formats/oboInOwl#ObsoleteClass> .

obo:OBI_0002423 a rdfs:Class ;
  rdfs:label "age of majority inclusion criterion" ;
  rdfs:comment "An inclusion criterion that uses the age of majority for a state or institution, where one is generally considered to be an adult, which if met, makes an individual suitable for a given task or participation in a given process." ;
  rdfs:subClassOf obo:OBI_0500027 .

obo:OBI_0002557 a rdfs:Class ;
  rdfs:label "maximum age value specification"@en ;
  rdfs:comment "A value specifcation that specifies the oldest age when specifying an age range."@en ;
  rdfs:subClassOf obo:OBI_0001933 .

obo:OBIB_0000157 a rdfs:Class ;
  rdfs:label "bilateral oophorectomy" ;
  rdfs:comment "A surgical procedure with the removal of both ovaries." ;
  rdfs:subClassOf obo:OBIB_0000716 .

obo:OBIB_0000554 a rdfs:Class ;
  rdfs:label "clinical history of animal tissue xenotransplant" ;
  rdfs:comment "A clinical  history in which there is a history of receiving an animal tissue or organ xenotransplant." ;
  rdfs:subClassOf obo:OGMS_0000015 .

obo:FMA_15584 a rdfs:Class ;
  rdfs:label "Cortex of left kidney" ;
  rdfs:subClassOf obo:UBERON_0000064 .

obo:OBI_0002550 a rdfs:Class ;
  rdfs:label "sigmoid colon specimen" ;
  rdfs:comment "A specimen that is derived from sigmoid colon." ;
  rdfs:subClassOf obo:OBI_0001479 .

obo:OBI_0002403 a rdfs:Class ;
  rdfs:label "hormonal birth control current use history" ;
  rdfs:comment "A hormonal birth control use history that indicates an individual is currently a hormonal birth control user." ;
  rdfs:subClassOf obo:OBI_0002401 .

obo:OBIB_0000586 a rdfs:Class ;
  rdfs:label "clinical history of exposure to Severe Acute Respiratory Syndrome" ;
  rdfs:comment "A clinical history in which there is a history of recent contact with someone who has Severe Acute Respiratory Syndrome (SARS)." ;
  rdfs:subClassOf obo:OGMS_0000015 .

obo:OBIB_0000126 a rdfs:Class ;
  rdfs:label "proctectomy" ;
  rdfs:comment "A surgical procedure to remove all or part of the rectum. It is often needed to treat rectal cancer." ;
  rdfs:subClassOf obo:OBIB_0000716 .

obo:OBI_0002546 a rdfs:Class ;
  rdfs:label "liver specimen" ;
  rdfs:comment "A specimen that is derived from liver." ;
  rdfs:subClassOf obo:OBI_0001479 .

obo:OBIB_0000298 a rdfs:Class ;
  rdfs:label "adherence of stage and replicate numbers to FFPE tissue processing SOP" ;
  rdfs:comment "An information content entity that indicates whether the number of stages and replicates followed that prescribed in the FFPE tissue processing SOP." ;
  rdfs:subClassOf obo:IAO_0000030 .

obo:UBERON_0000995 a rdfs:Class ;
  rdfs:label "uterus" ;
  rdfs:comment "The female muscular organ of gestation in which the developing embryo or fetus is nourished until birth." ;
  rdfs:subClassOf obo:UBERON_0000064 .

obo:OBIB_0000691 a rdfs:Class ;
  rdfs:label "number of sampled human study participants objective"@en ;
  rdfs:comment "An objective specification that specifies the number of individuals to participate in a study and provide biological specimens to the study."@en ;
  rdfs:subClassOf obo:IAO_0000005 .

obo:OBIB_0000146 a rdfs:Class ;
  rdfs:label "specimen donor intraoperative urine excreted prior to organ excision volume measurement datum" ;
  rdfs:comment "A specimen donor intraoperative urine excreted volume measurement datum obtained during prior to organ excision." ;
  rdfs:subClassOf obo:OBIB_0000145 .

obo:IAO_0020016 a rdfs:Class ;
  rdfs:label "given name"@en ;
  rdfs:comment "A given name, in Western contexts often referred to as a first name, is a personal name that specifies and differentiates between members of a group of individuals, especially in a family, all of whose members usually share the same family name (surname). A given name is purposefully given, usually by a child's parents at or near birth, in contrast to an inherited one such as a family name"@en ;
  rdfs:subClassOf obo:IAO_0020015 .

obo:UBERON_0036149 a rdfs:Class ;
  rdfs:label "suprapubic skin" ;
  rdfs:comment "Area of skin in the hypoastric region of the abdomen." ;
  rdfs:subClassOf obo:UBERON_0002097 .

obo:OBIB_0000526 a rdfs:Class ;
  rdfs:label "duration of hormonal birth control use prior to enrollment" ;
  rdfs:comment "A time measurement datum that is the result of measuring the duration of use of hormonally based birth control prior to enrollment in a study." ;
  rdfs:subClassOf obo:IAO_0000416 .

obo:OBIB_0000023 a rdfs:Class ;
  rdfs:label "lab technician role"@en ;
  rdfs:comment "A worker role that performs the practical hands-on work in laboratories and is realized during study design execution." ;
  rdfs:subClassOf obo:OBI_0000116 .

obo:OBIB_0000633 a rdfs:Class ;
  rdfs:label "biobank's unique resource locator"@en ;
  rdfs:comment "A unique resource locator referring to the homepage of a biobank."@en ;
  rdfs:subClassOf obo:OBIB_0000632 .

obo:OBI_0001619 a rdfs:Class ;
  rdfs:label "specimen collection time measurement datum"@en ;
  rdfs:comment "A time measurement datum that is the measure of the time when the specimens are collected."@en ;
  rdfs:subClassOf obo:IAO_0000416 .

obo:OBIB_0000651 a rdfs:Class ;
  rdfs:label "name of sample collection or study contact person"@en ;
  rdfs:comment "A personal name that designates the person acting as contact for a sample collection or a study."@en ;
  rdfs:subClassOf obo:IAO_0020015 .

obo:OMIABIS_0000053 a rdfs:Class ;
  rdfs:label "obsolete flash frozen specimen" ;
  rdfs:subClassOf <http://www.geneontology.org/formats/oboInOwl#ObsoleteClass> .

obo:OBI_2000018 a rdfs:Class ;
  rdfs:label "leukocyte specimen" ;
  rdfs:comment "A specimen that is derived from some leukocytes" ;
  rdfs:subClassOf obo:OBI_0002599 .

obo:OBIB_0000041 a rdfs:Class ;
  rdfs:label "duration time of smoking regularly"@en ;
  rdfs:comment "A duration time of smoking about how long a person has been smoking regularly. (better to have criteria of regularly mean, such as smoke everyday)" ;
  rdfs:subClassOf obo:OBIB_0000053 .

obo:OMIABIS_0001022 a rdfs:Class ;
  rdfs:label "obsolete population based study design" ;
  rdfs:subClassOf <http://www.geneontology.org/formats/oboInOwl#ObsoleteClass> .

obo:OMIABIS_0001078 a rdfs:Class ;
  rdfs:label "obsolete hosting biobank" ;
  rdfs:subClassOf <http://www.geneontology.org/formats/oboInOwl#ObsoleteClass> .

obo:CHEBI_51371 a rdfs:Class ;
  rdfs:label "muscle relaxant" ;
  rdfs:comment "A drug used to produce muscle relaxation (excepting neuromuscular blocking agents). Its primary clinical and therapeutic use is the treatment of muscle spasm and immobility associated with strains, sprains, and injuries of the back and, to a lesser degree, injuries to the neck. Also used for the treatment of a variety of clinical conditions that have in common only the presence of skeletal muscle hyperactivity, for example, the muscle spasms that can occur in multiple sclerosis." ;
  rdfs:subClassOf obo:OGMS_0000148 .

obo:BFO_0000019 a rdfs:Class ;
  rdfs:label "quality"@en ;
  rdfs:subClassOf obo:BFO_0000020 .

obo:OBI_0001000 a rdfs:Class ;
  rdfs:label "questionnaire" ;
  rdfs:comment "A document with a set of printed or written questions with a choice of answers, devised for the purposes of a survey or statistical study."@en ;
  rdfs:subClassOf obo:IAO_0000310 .

obo:PATO_0000011 a rdfs:Class ;
  rdfs:label "age" ;
  rdfs:comment "A time quality inhering in a bearer by virtue of how long the bearer has existed." ;
  rdfs:subClassOf obo:PATO_0000165 .

obo:UBERON_0000057 a rdfs:Class ;
  rdfs:label "urethra" ;
  rdfs:comment "The fibromuscular tubular canal through which urine is discharged from the bladder to the exterior via the external urinary meatus; in males, the urethra is joined by the ejaculatory ducts and serves as a passageway for semen during ejaculation, as well as a canal for urine during voiding; in females, the urethra is shorter and emerges above the vaginal opening." ;
  rdfs:subClassOf obo:UBERON_0000465 .

obo:OBIB_0000314 a rdfs:Class ;
  rdfs:label "FFPE tissue block handling, tracking, and storage SOP" ;
  rdfs:comment "A standard operating procedure for the handling, tracking, and storing of a formalin-fixed paraffin-embedded (FFPE) tissue block." ;
  rdfs:subClassOf obo:OBIB_0000070 .

obo:GEO_000000370 a rdfs:Class ;
  rdfs:label "geographical entity"@en ;
  rdfs:comment "A material entity that is (1) a bona fide or fiat object part of the crust, any bodies of liquid on or contained within the crust, or planetary boundary layer (if present) of a terrestrial planet (including Earth), dwarf planet, exoplanet, natural satellite, planetesimal, or small Solar System body, and that (2) overlaps the planetary surface (including having a boundary that coincides with part of the planetary surface)."@en ;
  rdfs:subClassOf obo:BFO_0000040 .

obo:OBIB_0000151 a rdfs:Class ;
  rdfs:label "comment on donor pre-operative bowel preparation prior to surgery" ;
  rdfs:comment "A comment from tissue procurement of the pre-operative bowel preparation performed prior to surgery." ;
  rdfs:subClassOf obo:OBIB_0000712 .

obo:OBI_0000434 a rdfs:Class ;
  rdfs:label "adding material objective"@en ;
  rdfs:comment "is the specification of an objective to add a material into a target material. The adding is asymmetric in the sense that the target material largely retains its identity"@en ;
  rdfs:subClassOf obo:OBI_0000686 .

obo:OBIB_0000387 a rdfs:Class ;
  rdfs:label "name of submitter of pathology case summary report." ;
  rdfs:comment "A personal name that designates the person who was the submitter of a pathology case summary report." ;
  rdfs:subClassOf obo:IAO_0020015 .

obo:OBIB_0000347 a rdfs:Class ;
  rdfs:label "H&E staining equipment maintenance performed and recorded frequency value specification" ;
  rdfs:comment "A categorical value specification that is used to record the frequency with which hematoxylin and eosin (H&E) staining equipment maintenance is performed and recorded. Categories include daily, weekly, bi-monthly, and per SOP." ;
  rdfs:subClassOf obo:OBI_0001930 .

obo:OBIB_0000638 a rdfs:Class ;
  rdfs:label "telephone number of sample collection or study contact"@en ;
  rdfs:comment "A telephone number that is contact information about a sample collection or study contact person."@en ;
  rdfs:subClassOf obo:OBIB_0000634 .

obo:OBIB_0000307 a rdfs:Class ;
  rdfs:label "FFPE paraffin temperature" ;
  rdfs:comment "A scalar measurement datum that is the output of a temperature measurement assay performed on paraffin in a formalin-fixed paraffin-embedded (FFPE) process." ;
  rdfs:subClassOf obo:IAO_0000032 .

obo:UO_0000001 a rdfs:Class ;
  rdfs:label "length unit" ;
  rdfs:subClassOf obo:IAO_0000003 .

obo:OBIB_0000431 a rdfs:Class ;
  rdfs:label "percentage of tumor content of specimen sent to biobank" ;
  rdfs:comment "A data item that is the result of determining the percentage of tumor content of a specimen sent to a biobank." ;
  rdfs:subClassOf obo:IAO_0000027 .

obo:OBIB_0000590 a rdfs:Class ;
  rdfs:label "clinical history of syphilis" ;
  rdfs:comment "A clinical history in which there is a history of active syphilis infection or treatment for syphilis in the recent past." ;
  rdfs:subClassOf obo:OGMS_0000015 .

obo:OBIB_0000394 a rdfs:Class ;
  rdfs:label "percentage of tumor cellularity by cell count of the entire slide." ;
  rdfs:comment "A data item that is the result of determining the percentage of tumor nuclei by cell count of the entire specimen slide (number of tumor epithelial cell nuclei as compared to all cell nuclei)." ;
  rdfs:subClassOf obo:IAO_0000027 .

obo:OBIB_0000550 a rdfs:Class ;
  rdfs:label "clinical history of ascites" ;
  rdfs:comment "A clinical history in which there is a history of the presence of ascites fluid." ;
  rdfs:subClassOf obo:OGMS_0000015 .

obo:OBI_0002456 a rdfs:Class ;
  rdfs:label "gravidity inclusion criterion"@en ;
  rdfs:comment "An inclusion criterion that defines and states one or more gravidity statuses of an organism, which, if met, makes the entity suitable for a given task or participation in a given process."@en ;
  rdfs:subClassOf obo:OBI_0500027 .

obo:UBERON_0001157 a rdfs:Class ;
  rdfs:label "transverse colon" ;
  rdfs:comment "The proximal-distal subdivision of colon that runs transversely across the upper part of the abdomen, from the right to the left colic flexure. Continuous with the descending colon[BTO,modified]." ;
  rdfs:subClassOf obo:UBERON_0000064 .

obo:OBIB_0000471 a rdfs:Class ;
  rdfs:label "research authorization for post mortem specimen donation not obtained because legally authorized representative did not show up to the appointment as scheduled" ;
  rdfs:comment "A research authorization documentation for post mortem specimen donation in which authorization was not obtained because the the legally authorized representative did not show up to the appointment as scheduled." ;
  rdfs:subClassOf obo:OBIB_0000459 .

obo:OBI_0002521 a rdfs:Class ;
  rdfs:label "renal medulla specimen" ;
  rdfs:comment "A specimen that is derived from renal medulla." ;
  rdfs:subClassOf obo:OBI_0001479 .

obo:IAO_0000582 a rdfs:Class ;
  rdfs:label "time stamped measurement datum"@en ;
  rdfs:subClassOf obo:IAO_0000109 .

obo:ICO_0000147 a rdfs:Class ;
  rdfs:label "candidate eligible for study role"@en ;
  rdfs:comment "A role inhering in a participant who meets all eligibility criteria defined within a study protocol."@en ;
  rdfs:subClassOf obo:ICO_0000146 .

obo:OBIB_0000649 a rdfs:Class ;
  rdfs:label "study proper name"@en ;
  rdfs:comment "A proper name that designates a study."@en ;
  rdfs:subClassOf obo:IAO_0020000 .

obo:NCBITaxon_11103 a rdfs:Class ;
  rdfs:label "Hepacivirus C" ;
  rdfs:subClassOf obo:NCBITaxon_10239 .

obo:CHEBI_35341 a rdfs:Class ;
  rdfs:label "steroid" ;
  rdfs:comment "Any of naturally occurring compounds and synthetic analogues, based on the cyclopenta[a]phenanthrene carbon skeleton, partially or completely hydrogenated; there are usually methyl groups at C-10 and C-13, and often an alkyl group at C-17. By extension, one or more bond scissions, ring expansions and/or ring contractions of the skeleton may have occurred. Natural steroids are derived biogenetically from squalene which is a triterpene." ;
  rdfs:subClassOf obo:CHEBI_23367 .

obo:OBI_0000810 a rdfs:Class ;
  rdfs:label "informed consent process" ;
  rdfs:comment "A planned process in which a person or their legal representative is informed about key facts about potential risks and benefits of a process and makes a documented decision as to whether the person in question will participate." ;
  rdfs:subClassOf obo:OBI_0000011 .

obo:OBIB_0000716 a rdfs:Class ;
  rdfs:label "surgical procedure"@en ;
  rdfs:comment "A planned process that uses operative manual and instrumental techniques on a patient to investigate and/or treat a pathological condition such as disease or injury, or to help improve bodily function or appearance."@en ;
  rdfs:subClassOf obo:OBI_0000011 .

obo:BFO_0000035 a rdfs:Class ;
  rdfs:label "process boundary"@en ;
  rdfs:comment "p is a process boundary =Def. p is a temporal part of a process & p has no proper temporal parts. (axiom label in BFO2 Reference: [084-001])"@en ;
  rdfs:subClassOf obo:BFO_0000003 .

obo:OMIABIS_00001012 a rdfs:Class ;
  rdfs:label "obsolete normal state specimen datum" ;
  rdfs:subClassOf <http://www.geneontology.org/formats/oboInOwl#ObsoleteClass> .

obo:OMIABIS_0000060 a rdfs:Class ;
  rdfs:label "obsolete survey data" ;
  rdfs:subClassOf <http://www.geneontology.org/formats/oboInOwl#ObsoleteClass> .

obo:OBIB_0000119 a rdfs:Class ;
  rdfs:label "left hemicolectomy" ;
  rdfs:comment "A colectomy that is the surgical removal of the left side of the large intestine." ;
  rdfs:subClassOf obo:OAE_0001159 .

obo:OBI_0002374 a rdfs:Class ;
  rdfs:label "brother clinical history of cancer" ;
  rdfs:comment "A clinical history in which there is a diagnosis of cancer in a male sibling." ;
  rdfs:subClassOf obo:OBI_0002372 .

obo:OBI_0002650 a rdfs:Class ;
  rdfs:label "biopsy" ;
  rdfs:comment "A specimen collection that obtains a sample of tissue or cell from a living multicellular organism body for diagnostic purposes by means intended to be minimally invasive." ;
  rdfs:subClassOf obo:OBI_0600005 .

obo:OMIABIS_0000003 a rdfs:Class ;
  rdfs:label "obsolete biobank proper name" ;
  rdfs:subClassOf <http://www.geneontology.org/formats/oboInOwl#ObsoleteClass> .

obo:NCIT_C45503 a rdfs:Class ;
  rdfs:label "Lung Squamous Cell Carcinoma, Clear Cell Variant" ;
  rdfs:comment "A morphologic variant of squamous cell lung carcinoma characterized by the presence of clear cells." ;
  rdfs:subClassOf obo:DOID_3907 .

obo:OBI_0002774 a rdfs:Class ;
  rdfs:label "platelet-poor plasma specimen"@en ;
  rdfs:comment "A blood plasma specimen that is the output of some platelet-poor plasma preparation and is the portion of plasma that contains fewer than 10,000 platelets per microliter."@en ;
  rdfs:subClassOf obo:OBI_0100016 .

obo:NCBITaxon_32523 a rdfs:Class ;
  rdfs:label "Tetrapoda" ;
  rdfs:subClassOf obo:NCBITaxon_117571 .

obo:OBIB_0000052 a rdfs:Class ;
  rdfs:label "pipe smoking behavior"@en ;
  rdfs:comment "A smoking behavior that uses a smoking pipe to inhale or taste tobacco material." ;
  rdfs:subClassOf <http://www.ebi.ac.uk/efo/EFO_0004318> .

obo:OBIB_0000576 a rdfs:Class ;
  rdfs:label "clinical history of unexplained weight loss" ;
  rdfs:comment "A clinical history in which there is a history of unexplained weight loss." ;
  rdfs:subClassOf obo:OGMS_0000015 .

<http://www.geneontology.org/formats/oboInOwl#ObsoleteClass> a rdfs:Class ;
  rdfs:label "Obsolete Class" .

obo:OBIB_0000259 a rdfs:Class ;
  rdfs:label "specimen was processed in accordance with the specified SOP" ;
  rdfs:comment "An information content entity indicating whether the specimen was processed in accordance with the specified SOP." ;
  rdfs:subClassOf obo:IAO_0000030 .

obo:OBIB_0000407 a rdfs:Class ;
  rdfs:label "FFPE slide inconsistencies with findings of diagnostic pathology report" ;
  rdfs:comment "A textual entity that describes inconsistencies with findings of diagnostic pathology report upon review of a formalin-fixed paraffin-embedded (FFPE) slide." ;
  rdfs:subClassOf obo:IAO_0000300 .

obo:OBI_1200000 a rdfs:Class ;
  rdfs:label "FFPE specimen" ;
  rdfs:comment "A specimen that has been fixed in formalin and embedded in paraffin." ;
  rdfs:subClassOf obo:OBI_0000950 .

obo:PATO_0000140 a rdfs:Class ;
  rdfs:label "position" ;
  rdfs:comment "A spatial quality inhering in a bearer by virtue of the bearer's spatial location relative to other objects in the vicinity." ;
  rdfs:subClassOf obo:PATO_0001018 .

obo:OMRSE_00000205 a rdfs:Class ;
  rdfs:label "ethnic identity information content entity"@en ;
  rdfs:comment "A social identity information content entity that is about whether some person identifies as some ethnicity."@en ;
  rdfs:subClassOf obo:OMRSE_00000204 .

obo:OBIB_0000276 a rdfs:Class ;
  rdfs:label "date of receiving specimen transport" ;
  rdfs:comment "A data item indicating the calendar date when a specimen was received after transport from another institution." ;
  rdfs:subClassOf obo:IAO_0000027 .

obo:OBIB_0000619 a rdfs:Class ;
  rdfs:label "biobank proper name"@en ;
  rdfs:comment "An identifier in natural language referring  to a biobank."@en ;
  rdfs:subClassOf obo:IAO_0020000 .

obo:OMIABIS_00001011 a rdfs:Class ;
  rdfs:label "obsolete mixed state specimen datum" ;
  rdfs:subClassOf <http://www.geneontology.org/formats/oboInOwl#ObsoleteClass> .

obo:OBIB_0000287 a rdfs:Class ;
  rdfs:label "name of team leader for filling out tissue recovery form" ;
  rdfs:comment "A personal name that designates the person who is the leader of the team responsible for entering the tissue recovery form data." ;
  rdfs:subClassOf obo:IAO_0020015 .

obo:OBI_0000379 a rdfs:Class ;
  rdfs:label "mechanical function"@en ;
  rdfs:comment "A mechanical function is a function that is realised via mechanical work (through an certain amount of energy transferred by some force)."@en ;
  rdfs:subClassOf obo:BFO_0000034 .

obo:OBIB_0000380 a rdfs:Class ;
  rdfs:label "name of dissector of normal adjacent tissue to tumor for FFPE" ;
  rdfs:comment "A personal name that designates the person who performed the dissection of a normal tissue adjacent to a tumor for a formalin-fixed paraffin-embedded (FFPE) process." ;
  rdfs:subClassOf obo:IAO_0020015 .

obo:OMIABIS_0001000 a rdfs:Class ;
  rdfs:label "obsolete age interval information" ;
  rdfs:subClassOf <http://www.geneontology.org/formats/oboInOwl#ObsoleteClass> .

obo:OMRSE_00000208 a rdfs:Class ;
  rdfs:label "OMB not Hispanic or Latino identity information content entity"@en ;
  rdfs:comment "An OMB ethnic identity information content entity that is about some person's identifying as neither Hispanic nor Latino, which are intended to mean being of Cuban, Mexican, Puerto Rican, South or Central American, or other Spanish culture or origin, regardless of race."@en ;
  rdfs:subClassOf obo:OMRSE_00000206 .

obo:OBIB_0000197 a rdfs:Class ;
  rdfs:label "minimum amount of required pre-op blood not drawn" ;
  rdfs:comment "A reason for not banking pre-operative blood specimen which is a minimum amount of required pre-op blood was not drawn." ;
  rdfs:subClassOf obo:OBIB_0000195 .

obo:OBI_0000686 a rdfs:Class ;
  rdfs:label "material combination objective" ;
  rdfs:comment "is an objective to obtain an output material that contains several input materials." ;
  rdfs:subClassOf obo:OBI_0000456 .

obo:IAO_0020017 a rdfs:Class ;
  rdfs:label "family name"@en ;
  rdfs:comment "A family name (in Western contexts often referred to as a surname or last name) is typically a part of a person's name which has been passed, according to law or custom, from one or both parents to their children."@en ;
  rdfs:subClassOf obo:IAO_0020015 .

obo:OBIB_0000088 a rdfs:Class ;
  rdfs:label "followup required for specimen collection issue" ;
  rdfs:comment "A data item that is an indicator of whether further followup on a specimen collection issue is required." ;
  rdfs:subClassOf obo:IAO_0000027 .

obo:OBI_0000151 a rdfs:Class ;
  rdfs:label "filter paper" ;
  rdfs:comment "A device manufacture with the intent to provide a porous unsized paper used for filtering." ;
  rdfs:subClassOf obo:OBI_0000932 .

obo:OBI_0001928 a rdfs:Class ;
  rdfs:label "selection"@en ;
  rdfs:comment "A planned process which results in the creation of group of entity from a larger group by the application of predefined criteria."@en ;
  rdfs:subClassOf obo:OBI_0000011 .

obo:CLO_0000019 a rdfs:Class ;
  rdfs:label "immortal cell line cell" ;
  rdfs:comment "A cell line cell that is expected to be capable of an unlimited number of divisions, and is thus able to support indefinite propagation in vitro as part of an immortal cell line." ;
  rdfs:subClassOf obo:CLO_0000001 .

obo:IAO_0000144 a rdfs:Class ;
  rdfs:label "conclusion textual entity"@en ;
  rdfs:comment "A textual entity that expresses the results of reasoning about a problem, for instance as typically found towards the end of scientific papers."@en ;
  rdfs:subClassOf obo:IAO_0000300 .

obo:IDO_0000456 a rdfs:Class ;
  rdfs:label "immunosuppressed organism"@en ;
  rdfs:comment "An organism that is experiencing pregnancy-induced or pathologic immunosuppression."@en ;
  rdfs:subClassOf obo:OBI_0100026 .

obo:OBIB_0000459 a rdfs:Class ;
  rdfs:label "research authorization documentation for post mortem specimen donation" ;
  rdfs:comment "An authorization documentation that is the output of a research authorization for post mortem specimen donation." ;
  rdfs:subClassOf obo:ICO_0000075 .

obo:IAO_8000016 a rdfs:Class ;
  rdfs:label "taxonomic bridge ontology module"@en ;
  rdfs:subClassOf obo:IAO_8000004 .

obo:OBIB_0000340 a rdfs:Class ;
  rdfs:label "FFPE tissue section H&E cover slip protocol" ;
  rdfs:comment "A protocol describing the method for applying a cover slip used during the hematoxylin and eosin (H&E) stained slide preparation of a formalin-fixed paraffin-embedded (FFPE) tissue section." ;
  rdfs:subClassOf obo:OBI_0000272 .

obo:IAO_0020023 a rdfs:Class ;
  rdfs:label "authentication"@en ;
  rdfs:comment """Authentication is the act of checking or verifying an identity claim (that is either tacit or explicit).
"""@en ;
  rdfs:subClassOf obo:BFO_0000015 .

obo:NCIT_C126530 a rdfs:Class ;
  rdfs:label "South African" ;
  rdfs:comment "Denotes a person whose ancestry is in the country of South Africa." ;
  rdfs:subClassOf obo:OBI_0000181 .

obo:OBI_0002520 a rdfs:Class ;
  rdfs:label "heart specimen" ;
  rdfs:comment "A specimen that is derived from heart." ;
  rdfs:subClassOf obo:OBI_0001479 .

obo:OBIB_0000518 a rdfs:Class ;
  rdfs:label "pre-adjuvant performance status score" ;
  rdfs:comment "A timing of scoring performance status that occurs prior to adjuvant therapy to treat cancer." ;
  rdfs:subClassOf obo:OBIB_0000516 .

obo:NCIT_C45512 a rdfs:Class ;
  rdfs:label "Lung Colloid Adenocarcinoma" ;
  rdfs:comment "A morphologic variant of lung adenocarcinoma characterized by the presence of mucin pools containing islands of well differentiated adenocarcinoma cells." ;
  rdfs:subClassOf obo:DOID_3910 .

obo:OBIB_0000067 a rdfs:Class ;
  rdfs:label "anesthesia probe temperature measurement assay" ;
  rdfs:comment "An internal body temperature measurement assay where the temperature probe interfaces with the anesthesia vent monitor. Typically the thermometer is a rectal probe with a wire and connector that hooks up to the ekg/pulse ox/co2 monitor." ;
  rdfs:subClassOf obo:OBIB_0000063 .

obo:OBIB_0000448 a rdfs:Class ;
  rdfs:label "specimen donor clinical data entry was completed" ;
  rdfs:comment "An information content entity that is an indicator of whether clinical data entry was completed for a specimen donor." ;
  rdfs:subClassOf obo:IAO_0000030 .

obo:OBI_0000018 a rdfs:Class ;
  rdfs:label "material supplier role"@en ;
  rdfs:comment "a role realized through the process of supplying materials such as animal subjects, reagents or other materials used in an investigation."@en ;
  rdfs:subClassOf obo:OBI_0000947 .

obo:CHEBI_50913 a rdfs:Class ;
  rdfs:label "fixative" ;
  rdfs:comment "Any compound used for the purpose of preserving biological tissues from decay in such a way as to allow for the preparation of thin, stained sections for subsequent histological study." ;
  rdfs:subClassOf obo:BFO_0000023 .

obo:UBERON_0001323 a rdfs:Class ;
  rdfs:label "tibial nerve" ;
  rdfs:comment "The tibial nerve is a branch of the sciatic nerve. The tibial nerve passes through the popliteal fossa to pass below the arch of soleus. In the popliteal fossa the nerve gives off branches to gastrocnemius, popliteus, soleus and plantaris muscles, an articular branch to the knee joint, and a cutaneous branch that will become the sural nerve. The sural nerve is joined by fibres from the common peroneal nerve and runs down the calf to supply the lateral side of the foot. Below the soleus muscle the nerve lies close to the tibia and supplies the tibialis posterior, the flexor digitorum longus and the flexor hallucis longus. The nerve passes into the foot running posterior to the medial malleolus. Here it is bound down by the flexor retinaculum in company with the posterior tibial artery. [WP,unvetted]." ;
  rdfs:subClassOf obo:UBERON_0000477 .

obo:OMIABIS_00001006 a rdfs:Class ;
  rdfs:label "obsolete specimen disease state datum" ;
  rdfs:subClassOf <http://www.geneontology.org/formats/oboInOwl#ObsoleteClass> .

obo:OBIB_0000495 a rdfs:Class ;
  rdfs:label "presence of metastatic tumor exclusion criterion" ;
  rdfs:comment "An exclusion criterion that defines whether a metastatic tumor is present, which if met, makes an individual unsuitable for a given task or participation in a given process." ;
  rdfs:subClassOf obo:OBI_0500028 .

obo:OBI_0002746 a rdfs:Class ;
  rdfs:label "induced sputum specimen" ;
  rdfs:comment "A sputum specimen that is collected from an organism following its inhalation of a nebulized salt solution." ;
  rdfs:subClassOf obo:OBI_0002508 .

obo:CHEBI_33839 a rdfs:Class ;
  rdfs:label "macromolecule" ;
  rdfs:comment "A macromolecule is a molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass." ;
  rdfs:subClassOf obo:CHEBI_23367 .

obo:HANCESTRO_0021 a rdfs:Class ;
  rdfs:label "Chinese" ;
  rdfs:subClassOf obo:HANCESTRO_0008 .

obo:IAO_8000012 a rdfs:Class ;
  rdfs:label "species subset ontology module"@en ;
  rdfs:comment "A subset ontology that is crafted to either include or exclude a taxonomic grouping of species."@en ;
  rdfs:seeAlso <https://github.com/obophenotype/uberon/wiki/Taxon-constraints> ;
  rdfs:subClassOf obo:IAO_8000006 .

obo:BFO_0000020 a rdfs:Class ;
  rdfs:label "specifically dependent continuant"@en ;
  rdfs:comment "A continuant that inheres in or is borne by other entities. Every instance of A requires some specific instance of B which must always be the same."@en ;
  rdfs:subClassOf obo:BFO_0000002 .

obo:IDO_0000644 a rdfs:Class ;
  rdfs:label "pregnancy-induced immunosuppression"@en ;
  rdfs:comment "An immunosuppression induced by progesterone and other factors upregulated in pregnant women."@en ;
  rdfs:subClassOf obo:IDO_0000610 .

obo:UBERON_0000481 a rdfs:Class ;
  rdfs:label "multi-tissue structure" ;
  rdfs:comment "Anatomical structure that has as its parts two or more portions of tissue of at least two different types and which through specific morphogenetic processes forms a single distinct structural unit demarcated by bona-fide boundaries from other distinct structural units of different types." ;
  rdfs:subClassOf obo:UBERON_0000465 .

obo:OBIB_0000529 a rdfs:Class ;
  rdfs:label "duration of hormone replacement therapy prior to enrollment" ;
  rdfs:comment "A time measurement datum that is the result of measuring the duration of hormone replacement therapy prior to enrollment in a study." ;
  rdfs:subClassOf obo:IAO_0000416 .

obo:OBIB_0000182 a rdfs:Class ;
  rdfs:label "right nephroureterectomy" ;
  rdfs:comment "A surgical procedure that is minimally invasive to remove a patient's right renal pelvis, kidney, ureter, and bladder cuff." ;
  rdfs:subClassOf obo:OBIB_0000716 .

obo:OBIB_0000074 a rdfs:Class ;
  rdfs:label "SOP memorandum" ;
  rdfs:comment "A textual entity that is a short communication to provide advisory or informative matter about a standard operating procedure." ;
  rdfs:subClassOf obo:IAO_0000300 .

obo:OBIB_0002000 a rdfs:Class ;
  rdfs:label "specimen position"@en ;
  rdfs:comment "A position inhering in a specimen." ;
  rdfs:subClassOf obo:PATO_0000140 .

obo:OMIABIS_0000014 a rdfs:Class ;
  rdfs:label "obsolete name of biobank contact person" ;
  rdfs:subClassOf <http://www.geneontology.org/formats/oboInOwl#ObsoleteClass> .

obo:OBI_0002407 a rdfs:Class ;
  rdfs:label "pill delivery form for hormonal replacement therapy" ;
  rdfs:comment "A delivery form for hormonal replacement therapy that is a pill for oral administration." ;
  rdfs:subClassOf obo:OBI_0002406 .

obo:CHEBI_33696 a rdfs:Class ;
  rdfs:label "nucleic acid" ;
  rdfs:comment "A macromolecule made up of nucleotide units and hydrolysable into certain pyrimidine or purine bases (usually adenine, cytosine, guanine, thymine, uracil), D-ribose or 2-deoxy-D-ribose and phosphoric acid." ;
  rdfs:subClassOf obo:CHEBI_33839 .

obo:IAO_8000001 a rdfs:Class ;
  rdfs:label "base ontology module"@en ;
  rdfs:comment "An ontology module that comprises only of asserted axioms local to the ontology, excludes import directives, and excludes axioms or declarations from external ontologies."@en ;
  rdfs:seeAlso <https://github.com/INCATools/ontology-starter-kit/issues/50> ;
  rdfs:subClassOf obo:IAO_8000000 .

obo:OBI_0002385 a rdfs:Class ;
  rdfs:label "diagnosis of infectious disease" ;
  rdfs:comment "A diagnosis that is an assertion that a patient who is the subject of a diagnostic process has an infectious disease." ;
  rdfs:subClassOf obo:OGMS_0000073 .

obo:OBIB_0000587 a rdfs:Class ;
  rdfs:label "clinical history of West Nile Virus" ;
  rdfs:comment "A clinical history in which there is a history of West Nile Virus (WNV) infection." ;
  rdfs:subClassOf obo:OGMS_0000015 .

obo:OBIB_0000605 a rdfs:Class ;
  rdfs:label "indication of having resided in Europe during a specific time frame" ;
  rdfs:comment "An information content entity in which there is an indication of whether an individual resided in Europe during a specific time frame" ;
  rdfs:subClassOf obo:IAO_0000030 .

obo:OBIB_0000136 a rdfs:Class ;
  rdfs:label "oxygen desaturation epochs prior to organ excision description" ;
  rdfs:comment "A comment from tissue procurement of the epochs of oxygen desaturation of less than 92% for more than 5 minutes prior to organ excision." ;
  rdfs:subClassOf obo:OBIB_0000712 .

obo:UBERON_0002081 a rdfs:Class ;
  rdfs:label "cardiac atrium" ;
  rdfs:comment "Cardiac chamber in which blood enters the heart." ;
  rdfs:subClassOf obo:UBERON_0000064 .

obo:OBIB_0000175 a rdfs:Class ;
  rdfs:label "left kidney mass excision" ;
  rdfs:comment "A surgical procedure to remove a mass (growth or tumor) in the left kidney." ;
  rdfs:subClassOf obo:OBIB_0000716 .

obo:OBIB_0000123 a rdfs:Class ;
  rdfs:label "total colectomy" ;
  rdfs:comment "A colectomy that is resection of part of the colon or a resection of all of the colon without complete resection of the colon" ;
  rdfs:subClassOf obo:OAE_0001159 .

obo:OBIB_0000695 a rdfs:Class ;
  rdfs:label "longitudinal study design"@en ;
  rdfs:comment "A study design that involves repeated observations of the same entity over time. In the biobank context, longitudinal studies sample a group of people in a given time period, and study them at intervals by the acquisition and analyses of data and/or samples over time."@en ;
  rdfs:subClassOf obo:OBI_0500000 .

obo:OBI_0000066 a rdfs:Class ;
  rdfs:label "investigation"@en ;
  rdfs:comment "a planned process that consists of parts: planning, study design execution, documentation and which produce conclusion(s)."@en ;
  rdfs:subClassOf obo:OBI_0000011 .

obo:OBI_0002654 a rdfs:Class ;
  rdfs:label "needle biopsy" ;
  rdfs:comment "A biopsy that uses a hollow needle to extract cells." ;
  rdfs:subClassOf obo:OBI_0002650 .

obo:OBI_0002427 a rdfs:Class ;
  rdfs:label "radiation treatment within the recent past exclusion criterion" ;
  rdfs:comment "An exclusion criterion that defines whether radiation was received within a certain timeframe, which when met, makes an individual unsuitable for a given task or participation in a given process." ;
  rdfs:subClassOf obo:OBI_0500028 .

obo:UBERON_0002106 a rdfs:Class ;
  rdfs:label "spleen" ;
  rdfs:comment "The organ that functions to filter blood and to store red corpuscles and platelets." ;
  rdfs:subClassOf obo:UBERON_0000465 .

obo:OMIABIS_0001011 a rdfs:Class ;
  rdfs:label "obsolete count of current total human study participant" ;
  rdfs:subClassOf <http://www.geneontology.org/formats/oboInOwl#ObsoleteClass> .

obo:OBIB_0000045 a rdfs:Class ;
  rdfs:label "nicotine gum or lozenge"@en ;
  rdfs:comment "A processed material contains nicotine in a form of a chewing gum or a candy-like tablet. It delivers nicotine to the body via absorption by the tissues of the mouth.  It is commonly used as an aid in nicotine replacement therapy (NRT), a process for smoking cessation." ;
  rdfs:subClassOf obo:OBIB_0000048 .

obo:OBIB_0000709 a rdfs:Class ;
  rdfs:label "sample collection data update"@en ;
  rdfs:comment "A planned process which involves editing of specimen collection data into a database after its initial entry."@en ;
  rdfs:subClassOf obo:OBI_0000011 .

obo:IAO_0000578 a rdfs:Class ;
  rdfs:label "centrally registered identifier"@en ;
  rdfs:comment "An information content entity that consists of a CRID symbol and additional information about the CRID registry to which it belongs."@en ;
  rdfs:subClassOf obo:IAO_0000030 .

obo:OBIB_0000594 a rdfs:Class ;
  rdfs:label "clinical history of lupus" ;
  rdfs:comment "A clinical history in which there is a history of systemic lupus" ;
  rdfs:subClassOf obo:OGMS_0000015 .

obo:OBIB_0000598 a rdfs:Class ;
  rdfs:label "clinical history of rheumatoid arthritis" ;
  rdfs:comment "A clinical history in which there is a history of rheumatoid arthritis." ;
  rdfs:subClassOf obo:OGMS_0000015 .

obo:PATO_0000047 a rdfs:Class ;
  rdfs:label "biological sex" ;
  rdfs:comment "An organismal quality inhering in a bearer by virtue of the bearer's ability to undergo sexual reproduction in order to differentiate the individuals or types involved." ;
  rdfs:subClassOf obo:PATO_0001995 .

obo:OMIABIS_0000029 a rdfs:Class ;
  rdfs:label "obsolete settlement part of address" ;
  rdfs:subClassOf <http://www.geneontology.org/formats/oboInOwl#ObsoleteClass> .

obo:OBIB_0000112 a rdfs:Class ;
  rdfs:label "administration of anaesthetic" ;
  rdfs:comment "A planned process to administer anaesthetic in order to produce a loss of feeling." ;
  rdfs:subClassOf obo:OBI_0000011 .

obo:NCBITaxon_2759 a rdfs:Class ;
  rdfs:label "Eukaryota" ;
  rdfs:subClassOf obo:OBI_0100026 .

obo:OBIB_0000706 a rdfs:Class ;
  rdfs:label "donor patient registry data"@en ;
  rdfs:comment "Registry data for a patient who participates as a donor in a study."@en ;
  rdfs:subClassOf obo:OBIB_0000679 .

obo:OBI_0002526 a rdfs:Class ;
  rdfs:label "skin of body specimen" ;
  rdfs:comment "A specimen that is derived from skin." ;
  rdfs:subClassOf obo:OBI_0001479 .

obo:IDO_0001008 a rdfs:Class ;
  rdfs:label "immunosuppressed human experiencing HIV-based immunosuppression"@en ;
  rdfs:comment "An immunosuppressed organism that is a human experiencing HIV-based immunosuppression." ;
  rdfs:subClassOf obo:IDO_0000456 .

obo:OBIB_0000667 a rdfs:Class ;
  rdfs:label "survey data"@en ;
  rdfs:comment "A data item that contains the outcome of a survey."@en ;
  rdfs:subClassOf obo:IAO_0000027 .

obo:IAO_0000329 a rdfs:Class ;
  rdfs:label "running title"@en ;
  rdfs:comment "A shorter version of a document title"@en ;
  rdfs:subClassOf obo:IAO_0000305 .

obo:UBERON_0001981 a rdfs:Class ;
  rdfs:label "blood vessel" ;
  rdfs:comment "A vessel through which blood circulates in the body." ;
  rdfs:subClassOf obo:UBERON_0000465 .

obo:OBIB_0000624 a rdfs:Class ;
  rdfs:label "contacting"@en ;
  rdfs:comment "A planned process that involves a human being and is intended to initiate a communication with another human being."@en ;
  rdfs:subClassOf obo:OBI_0000011 .

obo:OBI_0001159 a rdfs:Class ;
  rdfs:label "age since egg laying measurement datum"@en ;
  rdfs:comment "An age measurement datum that is the result of the measurement of the age of an organism since egg laying, the process of the production of egg(s) by an organism." ;
  rdfs:subClassOf obo:OBI_0001167 .

obo:OBIB_0000415 a rdfs:Class ;
  rdfs:label "specimen transport from OR to gross room was performed as per SOP" ;
  rdfs:comment "An information content entity that is an indicator of whether transport of tissue from the operating room (OR) to the pathology gross room was performed in accordance with the relevant standard operating procedure (SOP)." ;
  rdfs:subClassOf obo:IAO_0000030 .

obo:CHEBI_49575 a rdfs:Class ;
  rdfs:label "diazepam" ;
  rdfs:comment "A 1,4-benzodiazepinone that is 1,3-dihydro-2H-1,4-benzodiazepin-2-one substituted by a chloro group at position 7, a methyl group at position 1 and a phenyl group at position 5." ;
  rdfs:subClassOf obo:CHEBI_23367 .

obo:UBERON_0001004 a rdfs:Class ;
  rdfs:label "respiratory system" ;
  rdfs:comment "Functional system which consists of structures involved in respiration." ;
  rdfs:subClassOf obo:UBERON_0000465 .

obo:OBIB_0000564 a rdfs:Class ;
  rdfs:label "clinical history of osteomyelitis" ;
  rdfs:comment "A clinical history in which there is a history of osteomyelitis." ;
  rdfs:subClassOf obo:OGMS_0000015 .

obo:OMIABIS_0000007 a rdfs:Class ;
  rdfs:label "obsolete ISO 3166-1 alpha-2 code for sample collection or study contact" ;
  rdfs:subClassOf <http://www.geneontology.org/formats/oboInOwl#ObsoleteClass> .

obo:OMRSE_00000219 a rdfs:Class ;
  rdfs:label "OMB white identity information content entity"@en ;
  rdfs:comment "An OMB racial identity information content entity that is about some person's identifying as white which is intended to mean having origins in any of the original peoples of Europe, the Middle East, or North Africa."@en ;
  rdfs:subClassOf obo:OMRSE_00000214 .

obo:OBI_0100060 a rdfs:Class ;
  rdfs:label "cultured cell population" ;
  rdfs:comment "A processed material comprised of a collection of cultured cells that has been continuously maintained together in culture and shares a common propagation history." ;
  rdfs:subClassOf obo:OBI_0000047 .

obo:OBIB_0000533 a rdfs:Class ;
  rdfs:label "colorectal cancer risk factor" ;
  rdfs:comment "A risk factor that is associated with increased likelihood of colorectal cancer." ;
  rdfs:subClassOf <http://www.ebi.ac.uk/efo/EFO_0003919> .

obo:OBI_0000245 a rdfs:Class ;
  rdfs:label "organization"@en ;
  rdfs:comment "An entity that can bear roles, has members, and has a set of organization rules. Members of organizations are either organizations themselves or individual people. Members can bear specific organization member roles that are determined in the organization rules. The organization rules also determine how decisions are made on behalf of the organization by the organization members."@en ;
  rdfs:subClassOf obo:BFO_0000040 .

obo:OAE_0001159 a rdfs:Class ;
  rdfs:label "colectomy" ;
  rdfs:comment "A surgery that is a surgical procedure to remove all or part of your colon." ;
  rdfs:subClassOf obo:OBIB_0000716 .

obo:OBIB_0000158 a rdfs:Class ;
  rdfs:label "left oophorectomy" ;
  rdfs:comment "A surgical procedure with the removal of the left ovary." ;
  rdfs:subClassOf obo:OBIB_0000716 .

obo:OBIB_0000643 a rdfs:Class ;
  rdfs:label "intra-settlement specification part of address"@en ;
  rdfs:comment "A textual entity that is part of a postal address and specifies the location inside the settlement (which is specified by another part of the address). This can be a street name and a house number, or just a number or a post-office box number."@en ;
  rdfs:subClassOf obo:IAO_0000300 .

obo:OBIB_0000063 a rdfs:Class ;
  rdfs:label "internal body temperature measurement assay" ;
  rdfs:comment "A temperature measurement assay to obtain the body temperature of an organism through placement of a thermometer in an internal cavity or organ." ;
  rdfs:subClassOf obo:OBI_0002140 .

obo:UBERON_0006618 a rdfs:Class ;
  rdfs:label "atrium auricular region" ;
  rdfs:comment "A small conical pouch projections located on the upper anterior portion of each atrium of the heart." ;
  rdfs:subClassOf obo:UBERON_0000481 .

obo:OBIB_0000507 a rdfs:Class ;
  rdfs:label "lifelong non-drinker of alcohol" ;
  rdfs:comment "An Alcohol Use History in which there is no alcohol consumption." ;
  rdfs:subClassOf obo:NCIT_C81229 .

obo:OBIB_0000549 a rdfs:Class ;
  rdfs:label "clinical history of fungal infections" ;
  rdfs:comment "A clinical history in which there is a history of fungal infections." ;
  rdfs:subClassOf obo:OGMS_0000015 .

obo:OBI_0002154 a rdfs:Class ;
  rdfs:label "CMV antibody assay" ;
  rdfs:comment "An antigen specific antibodies assay that is meant to detect antibodies that bind to cytomegalovirus (CMV) antigens." ;
  rdfs:subClassOf obo:OBI_0002145 .

obo:OBIB_0000240 a rdfs:Class ;
  rdfs:label "name of person receiving blood specimen in laboratory" ;
  rdfs:comment "A personal name that designates the person who received a blood specimen in the laboratory." ;
  rdfs:subClassOf obo:IAO_0020015 .

obo:DOID_1520 a rdfs:Class .

obo:OBIB_0000169 a rdfs:Class ;
  rdfs:label "laparoscopically assisted vaginal surgical method" ;
  rdfs:comment "A surgical method in which operations are performed through the vagina aided by laparoscopic tools and techniques." ;
  rdfs:subClassOf obo:OBIB_0000165 .

obo:GO_0032991 a rdfs:Class ;
  rdfs:label "protein-containing complex" ;
  rdfs:comment "A stable assembly of two or more macromolecules, i.e. proteins, nucleic acids, carbohydrates or lipids, in which at least one component is a protein and the constituent parts function together." ;
  rdfs:subClassOf obo:BFO_0000040 .

obo:UBERON_0001970 a rdfs:Class ;
  rdfs:label "bile" ;
  rdfs:comment "Vital aqueous secretion of the liver that is formed by hepatocytes and modified down stream by absorptive and secretory properties of the bile duct epithelium." ;
  rdfs:subClassOf obo:UBERON_0006314 .

obo:OBIB_0000683 a rdfs:Class ;
  rdfs:label "start date of sampling for biobank"@en ;
  rdfs:comment "A data item that indicates the time when the sampling of specimens for a biobank started."@en ;
  rdfs:subClassOf obo:IAO_0000027 .

obo:OBIB_0000699 a rdfs:Class ;
  rdfs:label "quality control study design"@en ;
  rdfs:comment "A study design where some aspect of the experiment is quality controlled for the purposes of quality assurance."@en ;
  rdfs:subClassOf obo:OBI_0500000 .

obo:FMA_63062 a rdfs:Class ;
  rdfs:label "Muscularis mucosae of abdominal part of esophagus" ;
  rdfs:subClassOf obo:UBERON_0004648 .

obo:OBIB_0000600 a rdfs:Class ;
  rdfs:label "clinical history of Alzheimer's disease" ;
  rdfs:comment "A clinical history in which there is a history of Alzheimer's Disease." ;
  rdfs:subClassOf obo:OGMS_0000015 .

obo:OBIB_0000193 a rdfs:Class ;
  rdfs:label "wedge resection of right lung" ;
  rdfs:comment "A surgical procedure to remove a triangle-shaped slice of tissue from the right lung. It may be used to remove a tumor or some other type of tissue that requires removal and typically includes a small amount of normal tissue around it." ;
  rdfs:subClassOf obo:OBIB_0000716 .

obo:OBI_0002514 a rdfs:Class ;
  rdfs:label "peritoneal fluid specimen" ;
  rdfs:comment "A specimen that is derived from peritoneal fluid." ;
  rdfs:subClassOf obo:OBI_2000009 .

obo:OGMS_0000148 a rdfs:Class ;
  rdfs:label "medication role" ;
  rdfs:comment "A role borne by some material entity which can be delivered/administrated into some organism and the role is realized during a clinical treatment process aiming to treat symptoms, signs or diagnosed disease." ;
  rdfs:subClassOf obo:BFO_0000023 .

obo:OBI_0002539 a rdfs:Class ;
  rdfs:label "tibial nerve specimen" ;
  rdfs:comment "A specimen that is derived from tibial nerve." ;
  rdfs:subClassOf obo:OBI_0001479 .

obo:OBIB_0000091 a rdfs:Class ;
  rdfs:label "comment on resolved specimen collection issue" ;
  rdfs:comment "A comment from tissue procurement made in regards to the resolution of an issue with the tissue." ;
  rdfs:subClassOf obo:OBIB_0000712 .

obo:OBIB_0000101 a rdfs:Class ;
  rdfs:label "preoperative intravenous administration of sedative" ;
  rdfs:comment "A planned process to administer sedation drugs intravenously prior to surgery in order to induce total or partial loss of sensation especially tactile sensation and pain." ;
  rdfs:subClassOf obo:OBI_0000011 .

obo:UBERON_0001987 a rdfs:Class ;
  rdfs:label "placenta" ;
  rdfs:comment "Organ of metabolic interchange between fetus and mother, partly of embryonic origin and partly of maternal origin[GO]. The fetal portion of the placenta is known as the villous chorion. The maternal portion is known as the decidua basalis. The two portions are held together by anchoring villi that are anchored to the decidua basalis by the cytotrophoblastic shell." ;
  rdfs:subClassOf obo:UBERON_0000465 .

obo:UBERON_0000029 a rdfs:Class ;
  rdfs:label "lymph node" ;
  rdfs:comment "Any of the rounded masses of lymphoid tissue that are surrounded by a capsule of connective tissue, are distributed along the lymphatic vessels, and contain numerous lymphocytes which filter the flow of lymph." ;
  rdfs:subClassOf obo:UBERON_0000465 .

obo:OBI_0002138 a rdfs:Class ;
  rdfs:label "temperature value specification"@en ;
  rdfs:comment "A value specification that specifies the temperature of some thing." ;
  rdfs:subClassOf obo:OBI_0001933 .

obo:OBI_0002600 a rdfs:Class ;
  rdfs:label "collecting specimen with swab" ;
  rdfs:comment "A specimen collection process that uses a swab as the collection device. A swab is an absorbent material (e.g. cotton) on a rod (e.g., wooden stick)." ;
  rdfs:subClassOf obo:OBI_0000659 .

obo:UBERON_0000970 a rdfs:Class ;
  rdfs:label "eye" ;
  rdfs:comment "An organ that detects light." ;
  rdfs:subClassOf obo:UBERON_0000465 .

obo:OBIB_0000403 a rdfs:Class ;
  rdfs:label "FFPE slide meets necrosis percentage and tumor content criteria" ;
  rdfs:comment "An information content entity that is an indicator of whether a formalin-fixed paraffin-embedded (FFPE) slide meets the microscopic analysis criteria with respect to necrosis percentage and tumor content." ;
  rdfs:subClassOf obo:IAO_0000030 .

obo:OBIB_0000039 a rdfs:Class ;
  rdfs:label "blood specimen on blood spot card"@en ;
  rdfs:comment "A blood specimen that is located on a blood spot card." ;
  rdfs:subClassOf obo:OBI_0000655 , obo:OBI_0000953 .

obo:OBI_0002615 a rdfs:Class ;
  rdfs:label "disease specific study design" ;
  rdfs:comment "A study design for which material and information is collected from subjects that have already developed a particular disease." ;
  rdfs:subClassOf obo:OBI_0500000 .

obo:OBIB_0000641 a rdfs:Class ;
  rdfs:label "settlement part of address"@en ;
  rdfs:comment "A textual entity that is part of a postal address and denotes a human settlement for the purpose of delivering mail."@en ;
  rdfs:subClassOf obo:IAO_0000300 .

obo:OBIB_0000131 a rdfs:Class ;
  rdfs:label "in vivo intraoperative ischemic period" ;
  rdfs:comment "A time measurement datum of the period between organ resection and the time of first clamping perfomed in vivo." ;
  rdfs:subClassOf obo:IAO_0000416 .

obo:OMIABIS_0000037 a rdfs:Class ;
  rdfs:label "obsolete study proper name" ;
  rdfs:subClassOf <http://www.geneontology.org/formats/oboInOwl#ObsoleteClass> .

obo:OMRSE_00000048 a rdfs:Class ;
  rdfs:label "material entity role"@en ;
  rdfs:subClassOf obo:BFO_0000023 .

obo:UBERON_0002367 a rdfs:Class ;
  rdfs:label "prostate gland" ;
  rdfs:comment "The prostate gland is a partly muscular, partly glandular body that is situated near the base of the mammalian male urethra and secretes an alkaline viscid fluid which is a major constituent of the ejaculatory fluid." ;
  rdfs:subClassOf obo:UBERON_0000465 .

obo:OBIB_0000470 a rdfs:Class ;
  rdfs:label "research authorization for post mortem specimen donation not obtained because legally authorized representative did not agree with the activity of biobanking" ;
  rdfs:comment "A research authorization documentation for post mortem specimen donation in which authorization was not obtained because the the legally authorized representative did not agree with the activity of biobanking." ;
  rdfs:subClassOf obo:OBIB_0000459 .

obo:OBIB_0000179 a rdfs:Class ;
  rdfs:label "right kidney mass excision" ;
  rdfs:comment "A surgical procedure to remove a mass (growth or tumor) in the right kidney." ;
  rdfs:subClassOf obo:OBIB_0000716 .

obo:IAO_0000109 a rdfs:Class ;
  rdfs:label "measurement datum"@en ;
  rdfs:comment "A measurement datum is an information content entity that is a recording of the output of a measurement such as produced by a device."@en ;
  rdfs:subClassOf obo:IAO_0000027 .

obo:OBIB_0000583 a rdfs:Class ;
  rdfs:label "clinical history of sexually transmitted disease" ;
  rdfs:comment "A clinical history in which there is a history of sexually transmitted diseases" ;
  rdfs:subClassOf obo:OGMS_0000015 .

obo:OBI_0600004 a rdfs:Class ;
  rdfs:label "human subject enrollment"@en ;
  rdfs:comment "A planned process with the objective to obtain a population of human subjects to participate in an investigation by determining eligibility of subjects and obtaining informed consent."@en ;
  rdfs:subClassOf obo:OBI_0001928 .

obo:UBERON_0000463 a rdfs:Class ;
  rdfs:label "organism substance" ;
  rdfs:comment "Material anatomical entity in a gaseous, liquid, semisolid or solid state; produced by anatomical structures or derived from inhaled and ingested substances that have been modified by anatomical structures as they pass through the body." ;
  rdfs:subClassOf obo:UBERON_0000465 .

obo:OBI_0000339 a rdfs:Class ;
  rdfs:label "planning"@en ;
  rdfs:comment "a process of creating or modifying a plan specification"@en ;
  rdfs:subClassOf obo:BFO_0000015 .

obo:DOID_4451 a rdfs:Class .

obo:OBI_0002380 a rdfs:Class ;
  rdfs:label "uncle clinical history of cancer" ;
  rdfs:comment "A clinical history in which there is a diagnosis of cancer in a male sibling of a parent." ;
  rdfs:subClassOf obo:OBI_0002372 .

obo:OBIB_0000147 a rdfs:Class ;
  rdfs:label "specimen donor intraoperative urine excreted at end of surgery volume measurement datum" ;
  rdfs:comment "A specimen donor intraoperative urine excreted volume measurement datum obtained at the end of surgery." ;
  rdfs:subClassOf obo:OBIB_0000145 .

obo:OBIB_0000426 a rdfs:Class ;
  rdfs:label "pathology ink used on resected tissue specimen" ;
  rdfs:comment "An information content entity that is an indicator of whether pathology ink was used to mark the resected tissue specimen." ;
  rdfs:subClassOf obo:IAO_0000030 .

obo:OBI_0302914 a rdfs:Class ;
  rdfs:label "digital curation"@en ;
  rdfs:comment "Digital curation is the process of establishing and developing long term repositories of digital assets for current and future reference by researchers, scientists, and historians, and scholars generally."@en ;
  rdfs:subClassOf obo:IAO_0000572 .

obo:OBI_0000444 a rdfs:Class ;
  rdfs:label "target of material addition role"@en ;
  rdfs:comment "A role of a material entity that is realized in an \"adding a material entity into a target\" process where the bearer of the role (the target) receives the addition of another material entity." ;
  rdfs:subClassOf obo:OMRSE_00000048 .

obo:OBIB_0000351 a rdfs:Class ;
  rdfs:label "transplant alert associated with specimen donor" ;
  rdfs:comment "A textual entity that is a notification within a clinical data repository that a specimen donor was a transplant recipient." ;
  rdfs:subClassOf obo:IAO_0000300 .

obo:OBIB_0000481 a rdfs:Class ;
  rdfs:label "relationship between person signing research authorization and specimen donor" ;
  rdfs:comment "A relationship that may be biological or legal, between the specimen donor and the legally authorized representative who signed the research authorization." ;
  rdfs:subClassOf obo:BFO_0000020 .

obo:OBIB_0000538 a rdfs:Class ;
  rdfs:label "familial adenomatous polyposis colorectal cancer risk factor" ;
  rdfs:comment "A colorectal cancer risk factor that is having familial adenomatous polyposis or having a family member with familial adenomatous polyposis." ;
  rdfs:subClassOf obo:OBIB_0000533 .

obo:IAO_8000005 a rdfs:Class ;
  rdfs:label "import ontology module"@en ;
  rdfs:comment "A subset ontology module that is intended to be imported from another ontology."@en ;
  rdfs:seeAlso <http://robot.obolibrary.org/extract> ;
  rdfs:subClassOf obo:IAO_8000006 .

obo:OBIB_0000430 a rdfs:Class ;
  rdfs:label "percentage of gross area of necrosis of a specimen sent to biobank" ;
  rdfs:comment "A data item that is the result of determining the percentage of gross area of necrosis of a specimen sent to a biobank." ;
  rdfs:subClassOf obo:IAO_0000027 .

obo:IAO_0000003 a rdfs:Class ;
  rdfs:label "measurement unit label"@en ;
  rdfs:comment "A measurement unit label is as a label that is part of a scalar measurement datum and denotes a unit of measure."@en ;
  rdfs:subClassOf obo:IAO_0000009 .

obo:NCIT_C40038 a rdfs:Class ;
  rdfs:label "Borderline Ovarian Mucinous Tumor, Endocervical-Like" ;
  rdfs:comment "A neoplasm of low malignant potential arising from the ovary.  It is characterized by the proliferation of neoplastic epithelial cells that resemble endocervical epithelial cells.  There is no evidence of stromal invasion." ;
  rdfs:subClassOf obo:DOID_6067 .

obo:OBI_0302886 a rdfs:Class ;
  rdfs:label "centrifugation"@en ;
  rdfs:comment "centrifugation is a process separating molecules by size or density using centrifugal forces generated by a spinning rotor. G-forces of several hundred thousand times gravity are generated in ultracentrifugation"@en ;
  rdfs:subClassOf obo:OBI_0600014 .

obo:GO_0006955 a rdfs:Class ;
  rdfs:label "immune response" ;
  rdfs:comment "Any immune system process that functions in the calibrated response of an organism to a potential internal or invasive threat." ;
  rdfs:subClassOf obo:GO_0008150 .

obo:OBIB_0000441 a rdfs:Class ;
  rdfs:label "specimen collection quality review comment" ;
  rdfs:comment "A textual entity that states information relevant to a review to determine if requirements were met for a specimen collection from a donor." ;
  rdfs:subClassOf obo:IAO_0000300 .

obo:OBIB_0000613 a rdfs:Class ;
  rdfs:label "indication of tattoo from non-professional" ;
  rdfs:comment "An information content entity in which there is an indication of whether an individual has signs of non-professional  tattoos." ;
  rdfs:subClassOf obo:IAO_0000030 .

obo:UBERON_0002469 a rdfs:Class ;
  rdfs:label "esophagus mucosa" ;
  rdfs:comment "A mucosa that is part of a esophagus [Automatically generated definition]." ;
  rdfs:subClassOf obo:UBERON_0000465 .

obo:OBI_2000011 a rdfs:Class ;
  rdfs:label "meconium specimen" ;
  rdfs:comment "A specimen that is derived from some meconium" ;
  rdfs:subClassOf obo:OBI_0002503 .

obo:IAO_0000305 a rdfs:Class ;
  rdfs:label "document title"@en ;
  rdfs:comment "A textual entity that names a document"@en ;
  rdfs:subClassOf obo:IAO_0000300 .

obo:OBIB_0000030 a rdfs:Class ;
  rdfs:label "blood spot card"@en ;
  rdfs:comment "A device that  is designed to collect, ship and store blood specimens in an easy and inexpensive way." ;
  rdfs:subClassOf obo:OBI_0000967 .

obo:OBIB_0000391 a rdfs:Class ;
  rdfs:label "pathologist submitted specimen procurement feedback" ;
  rdfs:comment "A comment from tissue procurement that was submitted as feedback by a pathologist" ;
  rdfs:subClassOf obo:OBIB_0000712 .

obo:OBIB_0000362 a rdfs:Class ;
  rdfs:label "weight of frozen tissue specimen" ;
  rdfs:comment "A mass measurement datum that is the result of measuring the weight of a frozen tissue specimen." ;
  rdfs:subClassOf obo:IAO_0000414 .

obo:OMRSE_00000216 a rdfs:Class ;
  rdfs:label "OMB Asian identity information content entity"@en ;
  rdfs:comment "An OMB racial identity information content entity that is about some person's identifying as Asian, which is intended to mean having origins in any of the original peoples of the Far East, Southeast Asia, or the Indian subcontinent."@en ;
  rdfs:subClassOf obo:OMRSE_00000214 .

obo:ICO_0000023 a rdfs:Class ;
  rdfs:label "completely filled informed consent form"@en ;
  rdfs:comment "An informed consent form that has been filled with all required contents."@en ;
  rdfs:subClassOf obo:ICO_0000001 .

obo:NCIT_C27891 a rdfs:Class ;
  rdfs:label "Renal Cell Carcinoma Associated with Xp11.2 Translocations/TFE3 Gene Fusions" ;
  rdfs:comment "A group of renal cell carcinomas characterized by the presence of different translocations involving the chromosome Xp11.2. These translocations result in the creation of gene fusions involving the TFE3 gene. Patients are usually children and young adults. Morphologically, the malignant epithelial cells form papillary patterns." ;
  rdfs:subClassOf obo:DOID_4451 .

obo:OMIABIS_0000025 a rdfs:Class ;
  rdfs:label "obsolete telephone number of sample collection or study contact" ;
  rdfs:subClassOf <http://www.geneontology.org/formats/oboInOwl#ObsoleteClass> .

obo:OBIB_0000571 a rdfs:Class ;
  rdfs:label "indication of male homosexual sexual activity" ;
  rdfs:comment "An information content entity in that indicates whether a man has ever had sex with another man." ;
  rdfs:subClassOf obo:IAO_0000030 .

obo:OBI_0002402 a rdfs:Class ;
  rdfs:label "hormonal birth control former use history" ;
  rdfs:comment "A hormonal birth control use history that indicates an individual has previously been a hormonal birth control user but is not a current user." ;
  rdfs:subClassOf obo:OBI_0002401 .

obo:OBIB_0000531 a rdfs:Class ;
  rdfs:label "comment on the use of hormone replacement therapy" ;
  rdfs:comment "A textual entity that states additional information relevant to the use of hormone replacement therapy." ;
  rdfs:subClassOf obo:IAO_0000300 .

obo:OBI_0002391 a rdfs:Class ;
  rdfs:label "exposure to second hand smoke in household during childhood" ;
  rdfs:comment "An exposure to second hand smoke that occurred in the (patient's) household when the person was a child." ;
  rdfs:subClassOf obo:OBI_0002390 .

obo:CHEBI_6121 a rdfs:Class ;
  rdfs:label "ketamine" ;
  rdfs:comment "A member of the class of cyclohexanones in which one of the hydrogens at position 2 is substituted by a 2-chlorophenyl group, while the other is substituted by a methylamino group." ;
  rdfs:subClassOf obo:CHEBI_23367 .

obo:OBIB_0000078 a rdfs:Class ;
  rdfs:label "date of form data verification" ;
  rdfs:comment "A data item that reports the calendar date when the data collected on a form was verified." ;
  rdfs:subClassOf obo:IAO_0000027 .

obo:OBIB_0000632 a rdfs:Class ;
  rdfs:label "unique resource locator"@en ;
  rdfs:comment "A CRID that constitutes a reference to an Internet resource."@en ;
  rdfs:subClassOf obo:IAO_0000578 .

obo:UBERON_0002368 a rdfs:Class ;
  rdfs:label "endocrine gland" ;
  rdfs:comment "Endocrine glands are glands of the endocrine system that secrete their products directly into the circulatory system rather than through a duct.[WP, modified]." ;
  rdfs:subClassOf obo:UBERON_0000465 .

obo:APOLLO_SV_00000496 a rdfs:Class ;
  rdfs:label "ORCID"@en ;
  rdfs:comment "An identifier curated by ORCID, Inc. to denote some academic author."@en ;
  rdfs:subClassOf obo:IAO_0020000 .

obo:UBERON_0002199 a rdfs:Class ;
  rdfs:label "integument" ;
  rdfs:comment "The dermis, epidermis and hypodermis." ;
  rdfs:subClassOf obo:UBERON_0000465 .

obo:OBI_0002396 a rdfs:Class ;
  rdfs:label "age when gave birth to first child" ;
  rdfs:comment "An age measurement datum performed on a female when her first biological child was born." ;
  rdfs:subClassOf obo:OBI_0001167 .

obo:OBIB_0000205 a rdfs:Class ;
  rdfs:label "name of dissector of parent specimen" ;
  rdfs:comment "A personal name that designates the person who performed the dissection of a surgical specimen to create a specimen family." ;
  rdfs:subClassOf obo:IAO_0020015 .

obo:OBIB_0000186 a rdfs:Class ;
  rdfs:label "left lung lobectomy" ;
  rdfs:comment "A surgical procedure to remove one of the lobes of the left lung." ;
  rdfs:subClassOf obo:OBIB_0000716 .

obo:OBI_0000806 a rdfs:Class ;
  rdfs:label "material maintenance objective" ;
  rdfs:comment "An objective specification maintains some or all of the qualities of a material over time." ;
  rdfs:subClassOf obo:IAO_0000005 .

obo:OBIB_0000680 a rdfs:Class ;
  rdfs:label "date of data entry"@en ;
  rdfs:comment "A data item that indicates the time when data about the sample collection was reported into a database."@en ;
  rdfs:subClassOf obo:IAO_0000027 .

obo:OBIB_0000290 a rdfs:Class ;
  rdfs:label "comment on maintenance discrepancy from manufacturer recommendations" ;
  rdfs:comment "A textual entity that states information about maintenance discrepancies from manufacturer recommendations." ;
  rdfs:subClassOf obo:IAO_0000300 .

obo:OBIB_0000503 a rdfs:Class ;
  rdfs:label "date of radiation therapy prior to surgery" ;
  rdfs:comment "A data item that reports the calendar date when radiation therapy was received prior to surgery." ;
  rdfs:subClassOf obo:IAO_0000027 .

obo:OMIABIS_0001040 a rdfs:Class ;
  rdfs:label "obsolete specimen meeting specification" ;
  rdfs:subClassOf <http://www.geneontology.org/formats/oboInOwl#ObsoleteClass> .

obo:OBIB_0000700 a rdfs:Class ;
  rdfs:label "twin study design"@en ;
  rdfs:comment "A study design usually in behavior genetics which aids the study of individual differences between genetically identical twins by highlighting the role of environmental and genetic causes on behavior."@en ;
  rdfs:subClassOf obo:OBI_0500000 .

obo:OBI_0002409 a rdfs:Class ;
  rdfs:label "cream delivery form for hormonal replacement therapy" ;
  rdfs:comment "A delivery form for hormonal replacement therapy that is a cream for transdermal administration." ;
  rdfs:subClassOf obo:OBI_0002406 .

obo:OBI_0002429 a rdfs:Class ;
  rdfs:label "blood transfusion exclusion criterion" ;
  rdfs:comment "An exclusion criterion that is defined by whether the specimen donor received a whole blood transfusion within a specified time frame prior to death, which if met, makes a specimen donor unsuitable for a given task or participation in a given process." ;
  rdfs:subClassOf obo:OBI_0500028 .

obo:OMIABIS_0000019 a rdfs:Class ;
  rdfs:label "obsolete unique resource locator" ;
  rdfs:subClassOf <http://www.geneontology.org/formats/oboInOwl#ObsoleteClass> .

obo:UBERON_0002118 a rdfs:Class ;
  rdfs:label "right ovary" ;
  rdfs:comment "An ovary that is part of a right side of organism [Automatically generated definition]." ;
  rdfs:subClassOf obo:UBERON_0000992 .

obo:OBIB_0000284 a rdfs:Class ;
  rdfs:label "time of receipt for pathologist processing" ;
  rdfs:comment "A data item indicating the time when a specimen arrives in the gross pathology room for processing and review." ;
  rdfs:subClassOf obo:IAO_0000027 .

obo:OBIB_0000114 a rdfs:Class ;
  rdfs:label "administration of steroid during surgery" ;
  rdfs:comment "A planned process to administer steroid during a surgical procedure." ;
  rdfs:subClassOf obo:OBI_0000011 .

obo:OBIB_0000348 a rdfs:Class ;
  rdfs:label "comment on deviations from H&E equipment maintenance SOP" ;
  rdfs:comment "A textual entity that states information about deviations from a hemtoxylin and eosin (H&E) equipment maintenance standard operating procedure." ;
  rdfs:subClassOf obo:IAO_0000300 .

obo:OBIB_0000090 a rdfs:Class ;
  rdfs:label "reason for not collecting frozen specimens" ;
  rdfs:comment "A comment from tissue procurement that is an explanation as to why frozen specimens were not collected." ;
  rdfs:subClassOf obo:OBIB_0000712 .

obo:NCIT_C106501 a rdfs:Class ;
  rdfs:label "Birth Control Method" ;
  rdfs:comment "The method by which conception or impregnation is prevented. This may be achieved through the use of devices, drugs or surgery." ;
  rdfs:subClassOf obo:IAO_0000104 .

obo:OBI_0002559 a rdfs:Class ;
  rdfs:label "hospital patient inclusion criterion"@en ;
  rdfs:comment "An inclusion criterion defines that a human being has to be a hospital patient to be suitable for a given task or participation in a given process."@en ;
  rdfs:subClassOf obo:OBI_0500027 .

obo:OBIB_0002006 a rdfs:Class ;
  rdfs:label "specimen gross appearance of tumor center"@en ;
  rdfs:comment "A specimen gross appearance of the most internal topographic location of the tumor." ;
  rdfs:subClassOf obo:OBIB_0000209 .

obo:OBIB_0000445 a rdfs:Class ;
  rdfs:label "additional tumor specimen was obtained and processed with a particular FFPE fixation delay protocol" ;
  rdfs:comment "An information content entity that is an indicator of whether a tumor specimen was obtained and processed with a particular FFPE fixation delay protocol other than meeting the top priority for tissue procurement." ;
  rdfs:subClassOf obo:IAO_0000030 .

obo:OBIB_0000159 a rdfs:Class ;
  rdfs:label "right oophorectomy" ;
  rdfs:comment "A surgical procedure with the removal of the right ovary." ;
  rdfs:subClassOf obo:OBIB_0000716 .

obo:NCIT_C7983 a rdfs:Class ;
  rdfs:label "Borderline Ovarian Endometrioid Tumor/Atypical Proliferative Ovarian Endometrioid Tumor" ;
  rdfs:comment "An epithelial neoplasm that arises from the ovary characterized by the presence of glandular or cystic spaces which contain atypical glandular epithelial cells resembling endometrial cells. The surrounding ovarian stroma is often fibrotic. There is no evidence of stromal invasion." ;
  rdfs:subClassOf obo:DOID_5828 .

obo:OBIB_0000332 a rdfs:Class ;
  rdfs:label "comment on deviations from water bath daily maintenance SOP" ;
  rdfs:comment "A textual entity that states information about deviations from a water bath daily maintenance standard operating procedure." ;
  rdfs:subClassOf obo:IAO_0000300 .

obo:IAO_0000102 a rdfs:Class ;
  rdfs:label "data about an ontology part"@en ;
  rdfs:comment "Data about an ontology part is a data item about a part of an ontology, for example a term"@en ;
  rdfs:subClassOf obo:IAO_0000027 .

obo:OBIB_0000462 a rdfs:Class ;
  rdfs:label "research authorization documentation for post mortem specimen donation that is negative" ;
  rdfs:comment "A research authorization documentation for post mortem specimen donation establishing the lack of agreement for post-mortem donation and use in general research." ;
  rdfs:subClassOf obo:OBIB_0000459 .

obo:IAO_8000004 a rdfs:Class ;
  rdfs:label "bridge ontology module"@en ;
  rdfs:comment "An ontology module that consists entirely of axioms that connect or bridge two distinct ontology modules. For example, the Uberon-to-ZFA bridge module."@en ;
  rdfs:seeAlso <https://github.com/obophenotype/uberon/wiki/inter-anatomy-ontology-bridge-ontologies> ;
  rdfs:subClassOf obo:IAO_8000000 .

obo:NCBITaxon_388799 a rdfs:Class ;
  rdfs:label "HIV-1 group O" ;
  rdfs:subClassOf obo:NCBITaxon_11676 .

obo:OBIB_0000125 a rdfs:Class ;
  rdfs:label "low anterior resection" ;
  rdfs:comment "A surgical procedure that is done to treat cancer of the rectum in which the part of the rectum containing the cancer is removed. The remaining part of the rectum is reconnected to the colon." ;
  rdfs:subClassOf obo:OBIB_0000716 .

obo:UBERON_0001723 a rdfs:Class ;
  rdfs:label "tongue" ;
  rdfs:comment "A muscular organ in the floor of the mouth." ;
  rdfs:subClassOf obo:UBERON_0000465 .

obo:OBIB_0000108 a rdfs:Class ;
  rdfs:label "administration of intravenous anaesthetic" ;
  rdfs:comment "A planned process to administer anaesthetic within or into a vein or veins in order to produce a loss of feeling." ;
  rdfs:subClassOf obo:OBI_0000011 .

obo:UBERON_0001114 a rdfs:Class ;
  rdfs:label "right lobe of liver" ;
  rdfs:comment "The right lobe is much larger than the left; the proportion between them being as six to one. It occupies the right hypochondrium, and is separated from the left lobe on its upper surface by the falciform ligament; on its under and posterior surfaces by the left sagittal fossa; and in front by the umbilical notch. It is of a somewhat quadrilateral form, its under and posterior surfaces being marked by three fossæ: the porta and the fossæ for the gall-bladder and inferior vena cava, which separate its left part into two smaller lobes; the quadrate and caudate lobes. [WP,unvetted]." ;
  rdfs:subClassOf obo:UBERON_0000064 .

obo:OMIABIS_0001008 a rdfs:Class ;
  rdfs:label "obsolete comorbidity" ;
  rdfs:subClassOf <http://www.geneontology.org/formats/oboInOwl#ObsoleteClass> .

obo:OBIB_0000055 a rdfs:Class ;
  rdfs:label "pipe tobacco"@en ;
  rdfs:comment "A processed material which is made from tobacco for smoking tobacco using a pipe." ;
  rdfs:subClassOf obo:OBIB_0000057 .

obo:OBIB_0000373 a rdfs:Class ;
  rdfs:label "date and time FFPE tissue embedding started" ;
  rdfs:comment "A data item indicating the date and time when a tissue embedding started as part of a formalin-fixed paraffin-embedded (FFPE) process." ;
  rdfs:subClassOf obo:IAO_0000027 .

obo:OBIB_0000596 a rdfs:Class ;
  rdfs:label "clinical history of scleroderma" ;
  rdfs:comment "A clinical history in which there is a history of scleroderma." ;
  rdfs:subClassOf obo:OGMS_0000015 .

obo:OBIB_0000120 a rdfs:Class ;
  rdfs:label "sigmoid colectomy" ;
  rdfs:comment "A colectomy that is the surgical removal of the sigmoid colon." ;
  rdfs:subClassOf obo:OAE_0001159 .

obo:OBIB_0000492 a rdfs:Class ;
  rdfs:label "authorization for postmortem specimen donation for transplantation and research" ;
  rdfs:comment "An authorization documentation for postmortem specimen donation for a specified purpose which is for transplantation, research, education and the advancement of science." ;
  rdfs:subClassOf obo:OBIB_0000490 .

obo:OBI_0100017 a rdfs:Class ;
  rdfs:label "blood serum specimen"@en ;
  rdfs:comment "A material entity which derives from blood and corresponds to blood plasma without fibrinogen or the other clotting factors."@en ;
  rdfs:subClassOf obo:OBI_0000953 .

obo:OBI_0002087 a rdfs:Class ;
  rdfs:label "containing a specimen function"@en ;
  rdfs:comment "A contain function that involves physical contact with a specimen. This function is typically performed in such a way that the specimen is usable for an investigation or assay."@en ;
  rdfs:subClassOf obo:OBI_0000370 .

obo:OBIB_0000178 a rdfs:Class ;
  rdfs:label "left nephroureterectomy" ;
  rdfs:comment "A surgical procedure that is minimally invasive to remove a patient's left renal pelvis, kidney, ureter, and bladder cuff." ;
  rdfs:subClassOf obo:OBIB_0000716 .

obo:OBI_0002506 a rdfs:Class ;
  rdfs:label "pericardial fluid specimen" ;
  rdfs:comment "A specimen that is derived from pericardial fluid." ;
  rdfs:subClassOf obo:OBI_2000009 .

obo:OMIABIS_0000000 a rdfs:Class ;
  rdfs:label "obsolete biobank" ;
  rdfs:subClassOf <http://www.geneontology.org/formats/oboInOwl#ObsoleteClass> .

obo:OBIB_0000434 a rdfs:Class ;
  rdfs:label "comment on deviations in specimen dimensions from a tissue procurement SOP" ;
  rdfs:comment "A textual entity that states information relevant to deviations from a tissue procurement SOP with regards to specimen dimensions." ;
  rdfs:subClassOf obo:IAO_0000300 .

obo:OBI_0302874 a rdfs:Class ;
  rdfs:label "edited document"@en ;
  rdfs:comment "A document which is the output of a document editing process" ;
  rdfs:subClassOf obo:IAO_0000310 .

obo:OBI_0002528 a rdfs:Class ;
  rdfs:label "stomach specimen" ;
  rdfs:comment "A specimen that is derived from stomach." ;
  rdfs:subClassOf obo:OBI_0001479 .

obo:OBIB_0000226 a rdfs:Class ;
  rdfs:label "anesthesiologist role" ;
  rdfs:comment "A health care provider role borne by a medical practitioner trained in anesthesia and perioperative medicine." ;
  rdfs:subClassOf obo:OMRSE_00000012 .

obo:UBERON_0002107 a rdfs:Class ;
  rdfs:label "liver" ;
  rdfs:comment "An exocrine gland which secretes bile and functions in metabolism of protein and carbohydrate and fat, synthesizes substances involved in the clotting of the blood, synthesizes vitamin A, detoxifies poisonous substances, stores glycogen, and breaks down worn-out erythrocytes[GO]." ;
  rdfs:subClassOf obo:UBERON_0000465 .

obo:OMIABIS_0000052 a rdfs:Class ;
  rdfs:label "obsolete fixed tissue slide specimen" ;
  rdfs:subClassOf <http://www.geneontology.org/formats/oboInOwl#ObsoleteClass> .

obo:OBIB_0000150 a rdfs:Class ;
  rdfs:label "Duration of fasting by specimen donor prior to surgery" ;
  rdfs:comment "A time measurement datum of the duration of fasting by the specimen donor prior to surgery." ;
  rdfs:subClassOf obo:IAO_0000416 .

obo:UBERON_0001728 a rdfs:Class ;
  rdfs:label "nasopharynx" ;
  rdfs:comment "The section of the pharynx that lies above the soft palate." ;
  rdfs:subClassOf obo:UBERON_0000465 .

obo:OBI_0000960 a rdfs:Class ;
  rdfs:label "reagent application function" ;
  rdfs:comment "A function that is realized when a reagent is automatically added to some research material." ;
  rdfs:subClassOf obo:BFO_0000034 .

obo:OBIB_0000544 a rdfs:Class ;
  rdfs:label "clinical history of pneumonia" ;
  rdfs:comment "A clinical history in which there is a history of pneumonia." ;
  rdfs:subClassOf obo:OGMS_0000015 .

obo:UBERON_0000479 a rdfs:Class ;
  rdfs:label "tissue" ;
  rdfs:comment "Multicellular anatomical structure that consists of many cells of one or a few types, arranged in an extracellular matrix such that their long-range organisation is at least partly a repetition of their short-range organisation." ;
  rdfs:subClassOf obo:UBERON_0000465 .

obo:IAO_8000009 a rdfs:Class ;
  rdfs:label "single layer subset ontology module"@en ;
  rdfs:comment "A subset ontology that is largely comprised of a single layer or strata in an ontology class hierarchy. The purpose is typically for rolling up for visualization. The classes in the layer need not be disjoint."@en ;
  rdfs:subClassOf obo:IAO_8000006 .

obo:OMIABIS_0001037 a rdfs:Class ;
  rdfs:label "obsolete comment from tissue procurement" ;
  rdfs:subClassOf <http://www.geneontology.org/formats/oboInOwl#ObsoleteClass> .

obo:OGMS_0000023 a rdfs:Class ;
  rdfs:label "phenotype" ;
  rdfs:comment "A (combination of) quality(ies) of an organism determined by the interaction of its genetic make-up and environment that differentiates specific instances of a species from other instances of the same species."@en ;
  rdfs:subClassOf obo:BFO_0000019 .

obo:OBIB_0000308 a rdfs:Class ;
  rdfs:label "comment on FFPE tissue processing" ;
  rdfs:comment "A textual entity that states information relevant to tissue processing in a formalin-fixed paraffin-embedded (FFPE) process." ;
  rdfs:subClassOf obo:IAO_0000300 .

obo:OBI_0002553 a rdfs:Class ;
  rdfs:label "uterus specimen" ;
  rdfs:comment "A specimen that is derived from uterus." ;
  rdfs:subClassOf obo:OBI_0001479 .

obo:OBI_0002156 a rdfs:Class ;
  rdfs:label "rapid plasma reagin test" ;
  rdfs:comment "An analyte assay that is meant to detect with the aid of carbon or charcoal particles general antibodies that react with substances that are produced by cellular damage caused by Treponema pallidum indicating a syphilis infection. RPR tests can be done without a microscope." ;
  rdfs:subClassOf obo:OBI_0000443 .

obo:OBI_0000982 a rdfs:Class ;
  rdfs:label "computed tomography scanner" ;
  rdfs:comment "An image acquisition device that generates a three-dimensional image of the inside of an object from a large series of two-dimensional X-ray images taken around a single axis of rotation." ;
  rdfs:subClassOf obo:OBI_0000398 .

obo:OMIABIS_0000034 a rdfs:Class ;
  rdfs:label "obsolete name of hosted study collection" ;
  rdfs:subClassOf <http://www.geneontology.org/formats/oboInOwl#ObsoleteClass> .

obo:OBI_0002554 a rdfs:Class ;
  rdfs:label "vagina specimen" ;
  rdfs:comment "A specimen that is derived from vagina." ;
  rdfs:subClassOf obo:OBI_0001479 .

obo:OBIB_0000555 a rdfs:Class ;
  rdfs:label "clinical history of smallpox vaccination" ;
  rdfs:comment "A clinic history in which there is a history  of a recent of smallpox vaccination." ;
  rdfs:subClassOf obo:OGMS_0000015 .

obo:OBIB_0000610 a rdfs:Class ;
  rdfs:label "indication of intravenous drug use" ;
  rdfs:comment "An information content entity in which there is an indication of whether an individual has used illegal intravenous drugs  in a specified time frame." ;
  rdfs:subClassOf obo:IAO_0000030 .

obo:OBIB_0000251 a rdfs:Class ;
  rdfs:label "blood specimen volume in conical centrifuge tube" ;
  rdfs:comment "A blood specimen volume of blood contained in a conical centrifuge tube." ;
  rdfs:subClassOf obo:OBIB_0000236 .

obo:OBIB_0000423 a rdfs:Class ;
  rdfs:label "gross diagnosis of resected tissue" ;
  rdfs:comment "A diagnosis that is based on the gross evaluation of a resected tissue specimen." ;
  rdfs:subClassOf obo:OGMS_0000073 .

obo:OBI_0001866 a rdfs:Class ;
  rdfs:label "secondary cultured cell" ;
  rdfs:comment "A cultured cell that has been passaged or derives from a cell that has been passaged in culture." ;
  rdfs:subClassOf obo:CL_0000010 .

obo:OBI_0002606 a rdfs:Class ;
  rdfs:label "nasopharyngeal swab specimen" ;
  rdfs:comment "A specimen that is collected with a swab from the surface of a nasopharynx." ;
  rdfs:subClassOf obo:OBI_0002599 .

obo:OBI_0002513 a rdfs:Class ;
  rdfs:label "placenta specimen" ;
  rdfs:comment "A specimen that is derived from placenta." ;
  rdfs:subClassOf obo:OBI_0001479 .

obo:OBIB_0000484 a rdfs:Class ;
  rdfs:label "post mortem  donor role" ;
  rdfs:comment "A role borne by a person who has died from whom specimens are collected." ;
  rdfs:subClassOf obo:BFO_0000023 .

obo:OBIB_0000262 a rdfs:Class ;
  rdfs:label "cell pellet volume" ;
  rdfs:comment "A scalar measurement datum that is the output of a volume measurement assay that has a cell pellet as evaluant." ;
  rdfs:subClassOf obo:IAO_0000032 .

obo:OBI_0001161 a rdfs:Class ;
  rdfs:label "age since germination measurement datum"@en ;
  rdfs:comment "An age measurement datum that is the result of the measurement of the age of an organism since germination, the process consisting of physiological and developmental changes by a seed, spore, pollen grain (microspore), or zygote that occur after release from dormancy, and encompassing events prior to and including the first visible indications of growth." ;
  rdfs:subClassOf obo:OBI_0001167 .

obo:OMIABIS_0001026 a rdfs:Class ;
  rdfs:label "obsolete medical record" ;
  rdfs:subClassOf <http://www.geneontology.org/formats/oboInOwl#ObsoleteClass> .

obo:OBIB_0000566 a rdfs:Class ;
  rdfs:label "clinical history of unexplained weakness and fatigue" ;
  rdfs:comment "A clinical history in which there is a history of unexplained weakness and fatigue described as flu-like symptoms." ;
  rdfs:subClassOf obo:OGMS_0000015 .

obo:OMRSE_00000207 a rdfs:Class ;
  rdfs:label "OMB Hispanic or Latino identity information content entity"@en ;
  rdfs:comment "An OMB ethnic identity information content entity that is about some person's identifying as Hispanic or Latino, which are intended to mean being of Cuban, Mexican, Puerto Rican, South or Central American, or other Spanish culture or origin, regardless of race."@en ;
  rdfs:subClassOf obo:OMRSE_00000206 .

obo:OBI_0000971 a rdfs:Class ;
  rdfs:label "fresh specimen" ;
  rdfs:comment "a specimen that is output of a specimen creation process used for an investigation without storage." ;
  rdfs:subClassOf obo:OBI_0001472 .

obo:OBIB_0000456 a rdfs:Class ;
  rdfs:label "activity related to a particular specimen donor was stopped because tissue was not released to a biobank" ;
  rdfs:comment "An activity related to a particular specimen donor was stopped that is because the tissue was not released to a biobank." ;
  rdfs:subClassOf obo:OBIB_0000451 .

obo:OMIABIS_0001019 a rdfs:Class ;
  rdfs:label "obsolete longitudinal study design" ;
  rdfs:subClassOf <http://www.geneontology.org/formats/oboInOwl#ObsoleteClass> .

obo:UBERON_0000947 a rdfs:Class ;
  rdfs:label "aorta" ;
  rdfs:comment "The main trunk of the systemic arterial system that carries blood from the heart to all the organs and other structures of the body, bringing oxygenated blood to all parts of the body in the systemic circulation." ;
  rdfs:subClassOf obo:UBERON_0000465 .

obo:CHEBI_27338 a rdfs:Class ;
  rdfs:label "xylene" ;
  rdfs:subClassOf obo:CHEBI_23367 .

obo:OBIB_0000343 a rdfs:Class ;
  rdfs:label "manual FFPE tissue section H&E clearing" ;
  rdfs:comment "A planned process involving the manual performance of the FFPE tissue section H&E clearing protocol." ;
  rdfs:subClassOf obo:OBI_0000011 .

obo:OBIB_0000621 a rdfs:Class ;
  rdfs:label "biobank idenfier with ISO 3166-1 alpha-2 code"@en ;
  rdfs:comment "A biobank identifier that has an ISO 3166-1 alpha-2 code as a part."@en ;
  rdfs:subClassOf obo:OBIB_0000619 .

obo:CHEBI_35717 a rdfs:Class ;
  rdfs:label "sedative" ;
  rdfs:comment "A central nervous system depressant used to induce drowsiness or sleep or to reduce psychological excitement or anxiety." ;
  rdfs:subClassOf obo:OGMS_0000148 .

obo:UBERON_0008954 a rdfs:Class ;
  rdfs:label "lingula of left lung" ;
  rdfs:comment "Anterioinferior portion of left upper lung lobe." ;
  rdfs:subClassOf obo:UBERON_0000064 .

obo:OBI_0600052 a rdfs:Class ;
  rdfs:label "dialysis"@en ;
  rdfs:comment "a protocol application that uses diffusion through a semi-permeable membrane to separate an input material into two fractions of different composition"@en ;
  rdfs:subClassOf obo:OBI_0600014 .

obo:OBIB_0000022 a rdfs:Class ;
  rdfs:label "blood additive role"@en ;
  rdfs:comment "A material to be added role that is born by a chemical entity which is added into a blood collection containter to optimize specific blood component(s) preservation and/or separation." ;
  rdfs:subClassOf obo:OBI_0000319 .

obo:OBI_0002140 a rdfs:Class ;
  rdfs:label "temperature measurement assay" ;
  rdfs:comment "An assay to determine the temperature of an evaluant." ;
  rdfs:subClassOf obo:OBI_0000070 .

obo:OBIB_0000416 a rdfs:Class ;
  rdfs:label "specimen transport from OR to gross room issues or deviations from SOP" ;
  rdfs:comment "A textual entity that describes issues with the transport of tissue from the operating room (OR) to the pathology gross room or deviations from the relevant standard operating procedure (SOP)." ;
  rdfs:subClassOf obo:IAO_0000300 .

obo:UBERON_0002168 a rdfs:Class ;
  rdfs:label "left lung" ;
  rdfs:comment "Lung which consists of the left upper lobe and left lower lobe.[FMA]." ;
  rdfs:subClassOf obo:UBERON_0002048 .

obo:OBI_0002199 a rdfs:Class ;
  rdfs:label "reason for lack of data item" ;
  rdfs:comment "An information content entity that provides an explanation why a data item is not provided." ;
  rdfs:subClassOf obo:IAO_0000030 .

obo:OBI_0000917 a rdfs:Class ;
  rdfs:label "nasal swab specimen" ;
  rdfs:comment """A specimen obtained using a cotton swab on a stick, passed up the nostril to obtain a sample of
exudate and epithelial debris for microbiological or cellular examination.""" ;
  rdfs:subClassOf obo:OBI_0002599 .

obo:OBI_0302885 a rdfs:Class ;
  rdfs:label "filtration"@en ;
  rdfs:comment "filtration is a process which separates components suspended in a fluid based on granularity properties relying on a filter device"@en ;
  rdfs:subClassOf obo:OBI_0600014 .

obo:OBI_0000093 a rdfs:Class ;
  rdfs:label "patient role"@en ;
  rdfs:comment "a role which inheres in a person and is realized by the process of being under the care of a physician or health care provider"@en ;
  rdfs:subClassOf obo:OMRSE_00000048 .

obo:SO_0000001 a rdfs:Class ;
  rdfs:label "region" ;
  rdfs:comment "A sequence_feature with an extent greater than zero. A nucleotide region is composed of bases and a polypeptide region is composed of amino acids." ;
  rdfs:subClassOf obo:BFO_0000031 .

obo:OBI_0002424 a rdfs:Class ;
  rdfs:label "chemotherapy treatment exclusion criterion" ;
  rdfs:comment "An exclusion criterion that defines whether chemotherapy was received or is being received for a previous  or current cancer, which when met, makes an individual unsuitable for a given task or participation in a given process" ;
  rdfs:subClassOf obo:OBI_0500028 .

obo:UBERON_0005448 a rdfs:Class ;
  rdfs:label "greater omentum" ;
  rdfs:comment "The greater omentum (also the great omentum, omentum majus, gastrocolic omentum, epiploön, or, especially in animals, caul) is a large fold of peritoneum that hangs down from the stomach, and extends from the stomach to the posterior abdominal wall after associating with the transverse colon." ;
  rdfs:subClassOf obo:UBERON_0003688 .

obo:OBIB_0000661 a rdfs:Class ;
  rdfs:label "fixed tissue slide specimen"@en ;
  rdfs:comment "A fixed tissue specimen that is placed in a slide."@en ;
  rdfs:subClassOf obo:OBIB_0000659 .

obo:OBI_0002125 a rdfs:Class ;
  rdfs:label "H&E-stained fixed tissue slide specimen"@en ;
  rdfs:comment "A fixed tissue slide specimen that is the output of H&E slide staining."@en ;
  rdfs:subClassOf obo:BFO_0000002 , obo:OMIABIS_0000052 .

obo:IAO_0000032 a rdfs:Class ;
  rdfs:label "scalar measurement datum"@en ;
  rdfs:comment "A scalar measurement datum is a measurement datum that is composed of two parts, numerals and a unit label."@en ;
  rdfs:subClassOf obo:IAO_0000109 .

obo:OBIB_0000542 a rdfs:Class ;
  rdfs:label "testosterone hormone replacement therapy" ;
  rdfs:comment "A hormone replacement therapy where the hormone is testosterone." ;
  rdfs:subClassOf <http://www.ebi.ac.uk/efo/EFO_0003961> .

<http://www.ebi.ac.uk/efo/EFO_0003919> a rdfs:Class ;
  rdfs:label "risk factor" ;
  rdfs:comment "An aspect of personal behavior or lifestyle, environmental exposure, or inborn or inherited characteristic, which, on the basis of epidemiologic evidence, is known to be associated with a health-related condition considered important to prevent." ;
  rdfs:subClassOf obo:BFO_0000016 .

obo:OBIB_0000094 a rdfs:Class ;
  rdfs:label "cessation of brain activity death" ;
  rdfs:comment "A life-death temporal boundary marked by the irreversible end of all brain activity (including involuntary activity necessary to sustain life)." ;
  rdfs:subClassOf obo:UBERON_0035944 .

obo:UBERON_0009853 a rdfs:Class ;
  rdfs:label "body of uterus" ;
  rdfs:comment "The part of the uterus above the isthmus and below the orifices of the uterine tubes." ;
  rdfs:subClassOf obo:UBERON_0000064 .

obo:OBIB_0000273 a rdfs:Class ;
  rdfs:label "specimen receiving organization" ;
  rdfs:comment "A role borne by an organization that is the recipient of a specimen that is transported from another organization." ;
  rdfs:subClassOf obo:BFO_0000023 .

obo:OBIB_0000582 a rdfs:Class ;
  rdfs:label "clinical history of opportunistic infections" ;
  rdfs:comment "A clinical history in which there is a history of opportunistic infections." ;
  rdfs:subClassOf obo:OGMS_0000015 .

obo:OBIB_0000637 a rdfs:Class ;
  rdfs:label "post-office box"@en ;
  rdfs:comment "A post-office box is material entity that is a box on the premises of a post office station and is uniquely addressable."@en ;
  rdfs:subClassOf obo:BFO_0000040 .

obo:OBIB_0000449 a rdfs:Class ;
  rdfs:label "tumor specimen satisfied criteria of necrosis percentage and tumor content" ;
  rdfs:comment "An information content entity that is an indicator of whether the tumor specimen obtained satisfied criteria of necrosis percentage and tumor content of tumor cells by surface area." ;
  rdfs:subClassOf obo:IAO_0000030 .

obo:OBIB_0000553 a rdfs:Class ;
  rdfs:label "clinical history of human tissue transplant" ;
  rdfs:comment "A clinical  history in which there is a history of receiving a human tissue or organ transplant ." ;
  rdfs:subClassOf obo:OGMS_0000015 .

obo:OBIB_0000061 a rdfs:Class ;
  rdfs:label "postmortem collecting specimen from organism" ;
  rdfs:comment "A collection from organism that occurs after the organism is dead." ;
  rdfs:subClassOf obo:OBI_0600005 .

obo:OBIB_0000678 a rdfs:Class ;
  rdfs:label "average age"@en ;
  rdfs:comment "An average value of age for a certain group of individuals."@en ;
  rdfs:subClassOf obo:OBI_0000679 .

obo:OBIB_0000489 a rdfs:Class ;
  rdfs:label "agreement to a specified research addendum" ;
  rdfs:comment "An authorization documentation in which a legally authorized individual  agrees to a specific research addendum for the person they represent." ;
  rdfs:subClassOf obo:ICO_0000075 .

obo:OBI_0000112 a rdfs:Class ;
  rdfs:label "specimen role"@en ;
  rdfs:comment "a role borne by a material entity that is gained during a specimen collection process and that can be realized by use of the specimen in an investigation"@en ;
  rdfs:subClassOf obo:OMRSE_00000048 .

obo:OBIB_0000438 a rdfs:Class ;
  rdfs:label "no recurrence of tumor" ;
  rdfs:comment "An information content entity that is about the status of a tumor and indicates that there has not been a recurrence." ;
  rdfs:subClassOf obo:IAO_0000030 .

obo:OBI_0302716 a rdfs:Class ;
  rdfs:label "pool of specimens"@en ;
  rdfs:comment "A pool of specimens is a mixture of a population of samples which have been gathered from one or more sample populations, obtained by the physical process of mixing individual specimens, e.g.  mixing the DNA collected from the individual fish."@en ;
  rdfs:subClassOf obo:OBI_0000953 , obo:OBI_0100051 .

obo:OBI_0002398 a rdfs:Class ;
  rdfs:label "hysterectomy history" ;
  rdfs:comment "A gynecologic surgery history in which a woman has had a hysterectomy." ;
  rdfs:subClassOf obo:OBI_0002397 .

obo:OBI_0666666 a rdfs:Class ;
  rdfs:label "RNA extraction"@en ;
  rdfs:comment "A RNA extraction is a nucleic acid extraction where the desired output material is RNA"@en ;
  rdfs:subClassOf obo:OBI_0666667 .

obo:UBERON_0002032 a rdfs:Class ;
  rdfs:label "areola" ;
  rdfs:comment "Subdivision of breast which consists of skin, connective tissue and smooth muscle bundle and modified sebaceous glands and which surrounds the nipple." ;
  rdfs:subClassOf obo:UBERON_0000465 .

obo:OBI_0002393 a rdfs:Class ;
  rdfs:label "pregnancy history" ;
  rdfs:comment "A clinical history in which a female has had a pregnancy." ;
  rdfs:subClassOf obo:OGMS_0000015 .

obo:OBI_0000436 a rdfs:Class ;
  rdfs:label "needle" ;
  rdfs:comment "A needle is a sharp, hollow device used to penetrate tissue or soft material. When attached to a syringe. it allows delivery of a specific volume of liquid or gaseous mixture." ;
  rdfs:subClassOf obo:OBI_0000968 .

obo:OBI_0002430 a rdfs:Class ;
  rdfs:label "history of metastatic cancer exclusion criterion" ;
  rdfs:comment "An exclusion criterion defined as whether an individual has ever been diagnosed with metastatic cancer (cancer that spread beyond the initial site such as to other organs like brain bone or liver), which if met, makes the individual unsuitable for a given task or participation in a given process." ;
  rdfs:subClassOf obo:OBI_0500028 .

obo:OBIB_0000728 a rdfs:Class ;
  rdfs:label "specimen donor"@en ;
  rdfs:comment "A Homo sapiens who contributes specimen." ;
  rdfs:subClassOf obo:NCBITaxon_9606 .

obo:OBI_0002215 a rdfs:Class ;
  rdfs:label "histologic grade for ovarian tumor" ;
  rdfs:comment "A categorical value specification that is a histologic grade assigned to a ovarian tumor." ;
  rdfs:subClassOf obo:OBI_0001930 .

obo:CHEBI_6015 a rdfs:Class ;
  rdfs:label "isoflurane" ;
  rdfs:subClassOf obo:CHEBI_23367 .

obo:OBIB_0000337 a rdfs:Class ;
  rdfs:label "FFPE tissue section H&E deparaffinization protocol" ;
  rdfs:comment "A protocol describing the deparaffinization method used during the hematoxylin and eosin (H&E) stained slide preparation of a formalin-fixed paraffin-embedded (FFPE) tissue section." ;
  rdfs:subClassOf obo:OBI_0000272 .

obo:UBERON_0001156 a rdfs:Class ;
  rdfs:label "ascending colon" ;
  rdfs:comment "Section of colon which is distal to the cecum and proximal to the transversecolon.[FMA,modified]." ;
  rdfs:subClassOf obo:UBERON_0000064 .

obo:OBIB_0000672 a rdfs:Class ;
  rdfs:label "specimen disease state datum"@en ;
  rdfs:comment "A data item that indicates the pathological assessment of a specimen."@en ;
  rdfs:subClassOf obo:IAO_0000027 .

obo:BFO_0000148 a rdfs:Class ;
  rdfs:label "zero-dimensional temporal region"@en ;
  rdfs:subClassOf obo:BFO_0000008 .

obo:OBI_0001547 a rdfs:Class ;
  rdfs:label "material analysis service" ;
  rdfs:comment "A service in which a service consumer provides some input material and a service provider performs some analysis of this material to generate data that is returned to the service consumer." ;
  rdfs:subClassOf obo:OBI_0001528 .

obo:OBI_0000107 a rdf:Property ;
  rdfs:label "provides_service_consumer_with" ;
  rdfs:comment "A relation between a service and the primary processual part of the service that is performed by the provider for the consumer." ;
  rdfs:range <https://w3id.org/linkml/Any> ;
  rdfs:subPropertyOf obo:BFO_0000051 .

obo:OBI_0000202 a rdfs:Class ;
  rdfs:label "investigation agent role" ;
  rdfs:comment "A role borne by an entity and that is realized in a process that is part of an investigation in which an objective is achieved. These processes include, among others: planning, overseeing, funding, reviewing."@en ;
  rdfs:subClassOf obo:BFO_0000023 .

obo:OBI_0002387 a rdfs:Class ;
  rdfs:label "diagnosis of hepatitis C" ;
  rdfs:comment "A diagnosis of infectious disease caused by the hepatitis C virus." ;
  rdfs:subClassOf obo:OBI_0002385 .

obo:OBIB_0000593 a rdfs:Class ;
  rdfs:label "clinical history of Human Immunodeficiency Virus" ;
  rdfs:comment "A clinical history in which there is a history of Human Immunodeficiency Virus (HIV)." ;
  rdfs:subClassOf obo:OGMS_0000015 .

obo:IAO_0000646 a rdfs:Class ;
  rdfs:label "postal code"@en ;
  rdfs:comment "An identifier that denotes some postal delivery route, some aggregate of postal delivery routes or a geographical region and was created for the purpose of sorting and delivering mail."@en ;
  rdfs:subClassOf obo:IAO_0020000 .

obo:OBIB_0000689 a rdfs:Class ;
  rdfs:label "storage temperature setting"@en ;
  rdfs:comment "A setting datum that specifies the temperature inside a container participating in a storage process."@en ;
  rdfs:subClassOf obo:IAO_0000140 .

obo:OBIB_0000635 a rdfs:Class ;
  rdfs:label "telephone number of biobank contact"@en ;
  rdfs:comment "A telephone number that is contact information about a biobank contact person."@en ;
  rdfs:subClassOf obo:OBIB_0000634 .

obo:OBIB_0000615 a rdfs:Class ;
  rdfs:label "indication of having resided in Europe during specific time frame" ;
  rdfs:comment "An information content entity in which there is an indication of whether an individual lived in Europe for at least 5 years during a specific time." ;
  rdfs:subClassOf obo:IAO_0000030 .

obo:OBIB_0000134 a rdfs:Class ;
  rdfs:label "first temperature recorded in operating room of specimen donor" ;
  rdfs:comment "A time stamped measurement datum that is the first temperature recorded in the operating room of the specimen donor." ;
  rdfs:subClassOf obo:IAO_0000582 .

obo:OBI_0002192 a rdfs:Class ;
  rdfs:label "Leica Peloris rapid tissue processor" ;
  rdfs:comment "An automatic tissue processor that is a dual retort tissue processor manufactured by the Leica company to provide fast, high quality tissue processing for histology laboratories." ;
  rdfs:subClassOf obo:OBI_0001064 .

obo:OBIB_0000717 a rdfs:Class ;
  rdfs:label "specimen preparation contact"@en ;
  rdfs:comment "A personal name that designates the person who prepared the specimen."@en ;
  rdfs:subClassOf obo:IAO_0020015 .

obo:UBERON_0006314 a rdfs:Class ;
  rdfs:label "bodily fluid" ;
  rdfs:comment "Liquid components of living organisms. includes fluids that are excreted or secreted from the body as well as body water that normally is not." ;
  rdfs:subClassOf obo:UBERON_0000463 .

obo:OBI_0002610 a rdfs:Class ;
  rdfs:label "tongue swab specimen" ;
  rdfs:comment "A specimen that is collected with a swab from the surface of a tongue." ;
  rdfs:subClassOf obo:OBI_0002599 .

obo:IAO_8000019 a rdfs:Class ;
  rdfs:label "ontology module subsetted by OWL profile"@en ;
  rdfs:subClassOf obo:IAO_8000017 .

obo:OBI_0002151 a rdfs:Class ;
  rdfs:label "HCV antibody assay" ;
  rdfs:comment "An antigen specific antibodies assay that is meant to detect antibodies that bind to Hepacivirus C (HCV) antigens." ;
  rdfs:subClassOf obo:OBI_0002145 .

obo:GEO_000000004 a rdfs:Class ;
  rdfs:label "subnational entity"@en ;
  rdfs:comment "a governmental organization that has a local, regional, or territorial government that recognizes a sovereign state as its higher political authority"@en ;
  rdfs:subClassOf obo:GEO_000000400 .

obo:GEO_000000329 a rdf:Property ;
  rdfs:label "is subordinate authority of"@en ;
  rdfs:comment "A governing organization G1 is subordinate to another governing organization G2 iff there is some authority possessed by G2 that is not possessed by G1 and G1's jurisdiction falls within the relevant jurisdiction of G2."@en ;
  rdfs:range <https://w3id.org/linkml/Any> .

obo:OBIB_0000280 a rdfs:Class ;
  rdfs:label "specimen shipment received in good condition" ;
  rdfs:comment "An information content entity indicating that the physical condition of a specimen upon receipt after transport was good." ;
  rdfs:subClassOf obo:IAO_0000030 .

obo:OBI_0002548 a rdfs:Class ;
  rdfs:label "omentum specimen" ;
  rdfs:comment "A specimen that is derived from omentum." ;
  rdfs:subClassOf obo:OBI_0001479 .

obo:IDO_0001014 a rdfs:Class ;
  rdfs:label "immunosuppressed human experiencing drug-based immunosuppression due to organ transplant"@en ;
  rdfs:comment "A pathologically immunosuppressed organism that is a human experiencing drug-based immunosuppression." ;
  rdfs:subClassOf obo:IDO_0000456 .

obo:OBIB_0000668 a rdfs:Class ;
  rdfs:label "sampling specimens for biobank"@en ;
  rdfs:comment "The process of collecting or selecting an aggregate of specimens into a biobank."@en ;
  rdfs:subClassOf obo:OBI_0000011 .

obo:NCIT_C73993 a rdfs:Class ;
  rdfs:label "Pack Year" ;
  rdfs:comment "A quantification of lifetime tobacco exposure defined as (number of cigarettes smoked per day x number of years smoked)/20. One pack-year is smoking 20 cigarettes a day for one year." ;
  rdfs:subClassOf obo:IAO_0000003 .

obo:OBIB_0000646 a rdfs:Class ;
  rdfs:label "name of hosted study collection"@en ;
  rdfs:comment "The proper name that designates a hosted study collection."@en ;
  rdfs:subClassOf obo:IAO_0020000 , obo:OBIB_0000001 .

obo:OBIB_0000478 a rdfs:Class ;
  rdfs:label "name of person obtaining authorization from legally authorized representative for post-mortem specimen donation" ;
  rdfs:comment "A personal name of an individual with research obtainer role who approaches a person's legal representative and informs them of key facts about potential risks and benefits, and asks them for authorization for post-mortem specimen donation  for research for the person they legally represent." ;
  rdfs:subClassOf obo:IAO_0020015 .

obo:OBI_0002543 a rdfs:Class ;
  rdfs:label "atrial appendage specimen" ;
  rdfs:comment "A specimen that is derived from the atrium auricular region." ;
  rdfs:subClassOf obo:OBI_0001479 .

obo:OMIABIS_0001012 a rdfs:Class ;
  rdfs:label "obsolete physiological measurement data" ;
  rdfs:subClassOf <http://www.geneontology.org/formats/oboInOwl#ObsoleteClass> .

obo:OBI_0002531 a rdfs:Class ;
  rdfs:label "cortex of kidney specimen" ;
  rdfs:comment "A specimen that is derived from cortex of kidney." ;
  rdfs:subClassOf obo:OBI_0001479 .

obo:OBI_0002502 a rdfs:Class ;
  rdfs:label "cerebrospinal fluid specimen" ;
  rdfs:comment "A specimen that is derived from cerbrospinal fluid." ;
  rdfs:subClassOf obo:OBI_2000009 .

obo:OBI_0001010 a rdfs:Class ;
  rdfs:label "nucleic acid extract" ;
  rdfs:comment "An extract that is the output of an extraction process in which nucleic acid molecules are isolated from a specimen." ;
  rdfs:subClassOf obo:OBI_0000423 , obo:OBI_0000953 .

obo:OBI_0002435 a rdfs:Class ;
  rdfs:label "exposure to blood borne infectious disease exclusion criterion" ;
  rdfs:comment "An exclusion criterion defined  as whether an individual has been exposed to a blood borne infections disease through needle sticks and/or contact with non-intact skin and/or contact with open wounds and/or contact with mucous membranes, which if met, makes the individual unsuitable for a given task or participation in a given process." ;
  rdfs:subClassOf obo:OBI_0500028 .

obo:OBIB_0000473 a rdfs:Class ;
  rdfs:label "date of research protocol expiration as determined by an institutional review board" ;
  rdfs:comment "A data item that indicates the calendar date on which a research protocol expires and becomes inactive as determined by an Institutional Review Board." ;
  rdfs:subClassOf obo:IAO_0000027 .

obo:OBI_0000425 a rdfs:Class ;
  rdfs:label "averaging objective"@en ;
  rdfs:comment "An averaging objective is a data transformation objective where the aim is to perform mean calculations on the input of the data transformation."@en ;
  rdfs:subClassOf obo:OBI_0200166 .

obo:OMRSE_00000014 a rdfs:Class ;
  rdfs:label "nurse role"@en ;
  rdfs:comment "A health care role borne by a human being and realized by the care of individuals, families, and communities so they may attain, maintain, or recover optimal health and quality of life."@en ;
  rdfs:subClassOf obo:OMRSE_00000012 , obo:OMRSE_00000050 .

obo:OBIB_0000033 a rdfs:Class ;
  rdfs:label "specimen receiving"@en ;
  rdfs:comment "A planned process for receiving specimens such as into a laboratory." ;
  rdfs:subClassOf obo:OBI_0000011 .

obo:OMIABIS_0000056 a rdfs:Class ;
  rdfs:label "obsolete frozen tissue slide specimen" ;
  rdfs:subClassOf <http://www.geneontology.org/formats/oboInOwl#ObsoleteClass> .

obo:OBI_0600037 a rdfs:Class ;
  rdfs:label "cell culture splitting"@en ;
  rdfs:comment "The act of taking part of a homogeneous cell culture and creating one or more additional separate cultures of similar qualities. input: cell_culture, output cell_culture min cardinality 2. part of cell culturing"@en ;
  rdfs:subClassOf obo:OBI_0600014 .

obo:OBIB_0000365 a rdfs:Class ;
  rdfs:label "FFPE tissue cassette ID" ;
  rdfs:comment "A specimen ID that specifically identifies a particular tissue cassete used in a formalin-fixed paraffin-embedded (FFPE) process." ;
  rdfs:subClassOf obo:OBIB_0000721 .

obo:OMIABIS_0001001 a rdfs:Class ;
  rdfs:label "obsolete average age" ;
  rdfs:subClassOf <http://www.geneontology.org/formats/oboInOwl#ObsoleteClass> .

obo:OBIB_0000557 a rdfs:Class ;
  rdfs:label "clinical history of dialysis" ;
  rdfs:comment "A clinical history in which there is a history of significant regular dialysis treatment." ;
  rdfs:subClassOf obo:OGMS_0000015 .

obo:PATO_0001442 a rdfs:Class ;
  rdfs:label "wholeness" ;
  rdfs:comment "A structural quality inhering in a bearer by virtue of whether the bearer includes all its components." ;
  rdfs:subClassOf obo:PATO_0000051 .

obo:OBI_0002145 a rdfs:Class ;
  rdfs:label "antigen specific antibodies assay" ;
  rdfs:comment "An analyte assay that measures the presence or amount of antibodies to a specified antigen." ;
  rdfs:subClassOf obo:OBI_0000443 .

obo:OBI_0002405 a rdfs:Class ;
  rdfs:label "hormonal replacement therapy history" ;
  rdfs:comment "A clinical history in which an individual has had hormonal replacement therapy in the past." ;
  rdfs:subClassOf obo:OGMS_0000015 .

obo:OBIB_0000514 a rdfs:Class ;
  rdfs:label "current reformed smoker for more than 15 years history" ;
  rdfs:comment "A Smoking History in which there is no current smoking and has not been smoking for more than 15 years." ;
  rdfs:subClassOf obo:NCIT_C29719 .

obo:OMIABIS_0001082 a rdfs:Class ;
  rdfs:label "obsolete end of sampling specimens for biobank" ;
  rdfs:subClassOf <http://www.geneontology.org/formats/oboInOwl#ObsoleteClass> .

obo:OBIB_0000248 a rdfs:Class ;
  rdfs:label "comment from blood specimen storage" ;
  rdfs:comment "A textual entity that states additional information about the blood specimen or donor that is deemed relevant for the specimen storage process." ;
  rdfs:subClassOf obo:IAO_0000300 .

obo:NCBITaxon_33213 a rdfs:Class ;
  rdfs:label "Bilateria" ;
  rdfs:subClassOf obo:NCBITaxon_33154 .

obo:OBI_2000005 a rdfs:Class ;
  rdfs:label "respiratory system specimen" ;
  rdfs:comment "A specimen that is derived from some respiratory system" ;
  rdfs:subClassOf obo:OBI_0001479 .

obo:OBI_0002517 a rdfs:Class ;
  rdfs:label "hair specimen" ;
  rdfs:comment "A specimen that is derived from hair." ;
  rdfs:subClassOf obo:OBI_0001479 .

obo:OBIB_0000626 a rdfs:Class ;
  rdfs:label "biobank contact person"@en ;
  rdfs:comment "A human being that is member of a biobank organization and bears the organization contact role."@en ;
  rdfs:subClassOf obo:NCBITaxon_9606 .

obo:OBI_0000846 a rdf:Property ;
  rdfs:label "is member of organization" ;
  rdfs:comment "Relating a legal person or organization to an organization in the case where the legal person or organization has a role as member of the organization." ;
  rdfs:range <https://w3id.org/linkml/Any> .

obo:OBIB_0000574 a rdfs:Class ;
  rdfs:label "clinical history of growth hormone use" ;
  rdfs:comment "A clinical history in which there is a history of growth hormone use." ;
  rdfs:subClassOf obo:OGMS_0000015 .

obo:OMIABIS_0000045 a rdfs:Class ;
  rdfs:label "obsolete biobank location ISO 3166-1 alpha-2 code" ;
  rdfs:subClassOf <http://www.geneontology.org/formats/oboInOwl#ObsoleteClass> .

obo:OGMS_0000097 a rdfs:Class ;
  rdfs:label "health care encounter" ;
  rdfs:comment "A temporally-connected health care process that has as participants an organization or person realizing the health care provider role and a person realizing the patient role.  The health care provider role and patient are realized during the health care encounter"@en ;
  rdfs:subClassOf obo:BFO_0000015 .

obo:OBI_0002661 a rdfs:Class ;
  rdfs:label "tail biopsy" ;
  rdfs:comment "A biopsy involving the collection of the tip of a mamallian tail." ;
  rdfs:subClassOf obo:OBI_0002650 .

obo:OBIB_0000697 a rdfs:Class ;
  rdfs:label "panel study design"@en ;
  rdfs:comment "A longitudinal study that samples a cross-section and studies it at regular intervals."@en ;
  rdfs:subClassOf obo:OBIB_0000695 .

obo:OBIB_0000609 a rdfs:Class ;
  rdfs:label "indication of illegal prescription drug use" ;
  rdfs:comment "An information content entity in which there is an indication of whether an individual has used prescription pills that were not prescribed to them." ;
  rdfs:subClassOf obo:IAO_0000030 .

obo:OBIB_0000657 a rdfs:Class ;
  rdfs:label "CTEP organization identifier"@en ;
  rdfs:comment "An identifier for an organization that is assigned to that organization by the Cancer Therapy Evaluation Program."@en ;
  rdfs:subClassOf obo:IAO_0020000 .

obo:PATO_0000125 a rdfs:Class ;
  rdfs:label "mass" ;
  rdfs:comment "A physical quality that inheres in a bearer by virtue of the proportion of the bearer's amount of matter." ;
  rdfs:subClassOf obo:PATO_0001018 .

obo:OBIB_0000077 a rdfs:Class ;
  rdfs:label "first tissue removed date" ;
  rdfs:comment "A date of specimen collection for the first collection of a tissue from a donor." ;
  rdfs:subClassOf obo:OBIB_0000714 .

obo:CHEBI_30879 a rdfs:Class ;
  rdfs:label "alcohol" ;
  rdfs:comment "A compound in which a hydroxy group, -OH, is attached to a saturated carbon atom." ;
  rdfs:subClassOf obo:CHEBI_23367 .

obo:OBI_0002603 a rdfs:Class ;
  rdfs:label "areolar swab specimen" ;
  rdfs:comment "A specimen that is collected with a swab from the surface of an areola of a breast." ;
  rdfs:subClassOf obo:OBI_0002599 .

obo:IAO_0000300 a rdfs:Class ;
  rdfs:label "textual entity"@en ;
  rdfs:comment "A textual entity is a part of a manifestation (FRBR sense), a generically dependent continuant whose concretizations are patterns of glyphs intended to be interpreted as words, formulas, etc."@en ;
  rdfs:subClassOf obo:IAO_0000030 .

obo:BFO_0000003 a rdfs:Class ;
  rdfs:label "occurrent"@en ;
  rdfs:comment "An entity that has temporal parts and that happens, unfolds or develops through time."@en ;
  rdfs:subClassOf obo:BFO_0000001 .

obo:CHEBI_33250 a rdfs:Class ;
  rdfs:label "atom" ;
  rdfs:comment "A chemical entity constituting the smallest component of an element having the chemical properties of the element." ;
  rdfs:subClassOf obo:BFO_0000040 .

obo:UBERON_0001835 a rdfs:Class ;
  rdfs:label "lower lip" ;
  rdfs:comment "Lip that covers the lower portion of the mouth.[TAO]." ;
  rdfs:subClassOf obo:UBERON_0000465 .

obo:CHEBI_8430 a rdfs:Class ;
  rdfs:label "procaine" ;
  rdfs:comment "A benzoate ester, formally the result of esterification of 4-aminobenzoic acid with 2-diethylaminoethanol but formed experimentally by reaction of ethyl 4-aminobenzoate with 2-diethylaminoethanol." ;
  rdfs:subClassOf obo:CHEBI_23367 .

obo:OBI_0000836 a rdfs:Class ;
  rdfs:label "test tube" ;
  rdfs:comment "A test tube is a device consisting of a glass or plastic tubing, open at the top, usually with a rounded U-shaped bottom which has the function to contain material" ;
  rdfs:subClassOf obo:OBI_0000967 .

obo:OBIB_0000319 a rdfs:Class ;
  rdfs:label "FFPE tissue section preparation SOP" ;
  rdfs:comment "A standard operating procedure for the preparation of a formalin-fixed paraffin-embedded (FFPE) tissue section." ;
  rdfs:subClassOf obo:OBIB_0000070 .

obo:NCIT_C77820 a rdfs:Class ;
  rdfs:label "Middle Eastern" ;
  rdfs:comment "Denotes a person having origins in the region of southwest Asia, between the India subcontinent and Europe, including Kuwait, Turkey, Lebanon, Israel, Iraq, Iran, Jordan, Saudi Arabia, lands east of Pakistan or the other countries of the Arabian Peninsula.  Also includes people of Jewish ethnicity including Sephardic and Ashkenazic." ;
  rdfs:subClassOf obo:OBI_0000181 .

obo:OBIB_0000648 a rdfs:Class ;
  rdfs:label "sample collection or study aim description"@en ;
  rdfs:comment "A textual entity describing a study aim or a sample collection."@en ;
  rdfs:subClassOf obo:IAO_0000300 .

obo:OBI_2000002 a rdfs:Class ;
  rdfs:label "cervical mucus specimen" ;
  rdfs:comment "A specimen that is derived from some cervical mucus" ;
  rdfs:subClassOf obo:OBI_2000009 .

obo:GO_0019814 a rdfs:Class ;
  rdfs:label "immunoglobulin complex" ;
  rdfs:comment "A protein complex that in its canonical form is composed of two identical immunoglobulin heavy chains and two identical immunoglobulin light chains, held together by disulfide bonds and sometimes complexed with additional proteins. An immunoglobulin complex may be embedded in the plasma membrane or present in the extracellular space, in mucosal areas or other tissues, or circulating in the blood or lymph." ;
  rdfs:subClassOf obo:GO_0032991 .

obo:OMIABIS_0000030 a rdfs:Class ;
  rdfs:label "obsolete settlement part of address biobank contact" ;
  rdfs:subClassOf <http://www.geneontology.org/formats/oboInOwl#ObsoleteClass> .

obo:OBIB_0000599 a rdfs:Class ;
  rdfs:label "clinical history of idiopathic heart disease" ;
  rdfs:comment "A clinical history in which there is a history of idiopathic heart disease." ;
  rdfs:subClassOf obo:OGMS_0000015 .

obo:ICO_0000146 a rdfs:Class ;
  rdfs:label "eligibility of candidate participation"@en ;
  rdfs:comment "A role that represents the eligibility of a candidate according to a study protocol."@en ;
  rdfs:subClassOf obo:BFO_0000017 .

obo:OBIB_0000412 a rdfs:Class ;
  rdfs:label "sarcomatoid features observed on FFPE slide" ;
  rdfs:comment "A textual entity that describes sarcomatoid features observed on a formalin-fixed paraffin-embedded (FFPE) slide." ;
  rdfs:subClassOf obo:IAO_0000300 .

obo:OBIB_0000189 a rdfs:Class ;
  rdfs:label "right lung mass excision" ;
  rdfs:comment "A surgical procedure to remove a mass (growth or tumor) in the right lung." ;
  rdfs:subClassOf obo:OBIB_0000716 .

obo:OBIB_0000535 a rdfs:Class ;
  rdfs:label "obesity colorectal cancer risk factor" ;
  rdfs:comment "A colorectal cancer risk factor that is having been obese." ;
  rdfs:subClassOf obo:OBIB_0000533 .

obo:OBI_0002382 a rdfs:Class ;
  rdfs:label "grandfather clinical history of cancer" ;
  rdfs:comment "A clinical history in which there is a diagnosis of cancer in a male parent of a parent." ;
  rdfs:subClassOf obo:OBI_0002372 .

obo:OBIB_0000066 a rdfs:Class ;
  rdfs:label "organ temperature measurement assay" ;
  rdfs:comment "An internal body temperature measurement assay where the thermometer is placed in an organ." ;
  rdfs:subClassOf obo:OBIB_0000063 .

obo:OBI_0002376 a rdfs:Class ;
  rdfs:label "father clinical history of cancer" ;
  rdfs:comment "A clinical history in which there is a diagnosis of cancer in a male parent." ;
  rdfs:subClassOf obo:OBI_0002372 .

obo:OBIB_0000085 a rdfs:Class ;
  rdfs:label "organization conducting specimen collection from organism" ;
  rdfs:comment "An organization at which the process of collecting a specimen from an organism occurred." ;
  rdfs:subClassOf obo:OBI_0000245 .

obo:UBERON_0000362 a rdfs:Class ;
  rdfs:label "renal medulla" ;
  rdfs:comment "The inner portion of the kidney consisting of the renal pyramids." ;
  rdfs:subClassOf obo:UBERON_0000481 .

obo:OBIB_0000519 a rdfs:Class ;
  rdfs:label "post adjuvant performance status score" ;
  rdfs:comment "A timing of scoring performance status that occurs after adjuvant therapy to treat cancer." ;
  rdfs:subClassOf obo:OBIB_0000516 .

obo:OGMS_0000045 a rdfs:Class ;
  rdfs:label "disorder" ;
  rdfs:comment "A material entity which is clinically abnormal and part of an extended organism. Disorders are the physical basis of disease."@en ;
  rdfs:subClassOf obo:BFO_0000040 .

obo:CLO_0000031 a rdfs:Class ;
  rdfs:label "cell line"@en ;
  rdfs:comment """A cultured cell population that represents a genetically stable and homogenous population of cultured cells that shares a common propagation history (i.e. has been successively passaged together in culture).  
""" ;
  rdfs:subClassOf obo:OBI_0001905 .

obo:CHEBI_16991 a rdfs:Class ;
  rdfs:label "deoxyribonucleic acid" ;
  rdfs:comment "High molecular weight, linear polymers, composed of nucleotides containing deoxyribose and linked by phosphodiester bonds; DNA contain the genetic information of organisms." ;
  rdfs:subClassOf obo:CHEBI_33696 .

obo:OBIB_0000354 a rdfs:Class ;
  rdfs:label "comment on tissue specimen processing" ;
  rdfs:comment "A textual entity that states additional information deemed relevant for tissue specimen processing." ;
  rdfs:subClassOf obo:IAO_0000300 .

obo:UBERON_0007610 a rdfs:Class ;
  rdfs:label "tibial artery" ;
  rdfs:comment "The anterior and posterior arteries created at the bifurcation of the popliteal artery. The anterior tibial artery begins at the lower border of the popliteus muscle and lies along the tibia at the distal part of the leg to surface superficially anterior to the ankle joint. Its branches are distributed throughout the leg, ankle, and pes. The posterior tibial artery begins at the lower border of the popliteus muscle, lies behind the tibia in the lower part of its course, and is found situated between the medial malleolus and the medial process of the calcaneal tuberosity. Its branches are distributed throughout the leg and foot." ;
  rdfs:subClassOf obo:UBERON_0000465 .

obo:UBERON_0003688 a rdfs:Class ;
  rdfs:label "omentum" ;
  rdfs:comment "A fold of peritoneum originating at the stomach and supporting the viscera." ;
  rdfs:subClassOf obo:UBERON_0000064 .

obo:OBI_0002418 a rdfs:Class ;
  rdfs:label "exposure to diesel exhaust history" ;
  rdfs:comment "An exposure to environmental and workplace carcinogens history where the carcinogen is diesel exhaust." ;
  rdfs:subClassOf obo:OBI_0002415 .

obo:OBI_0000116 a rdfs:Class ;
  rdfs:label "worker role"@en ;
  rdfs:comment "a personnel role played by a party who executes a component of the study plan; this can occur before, during, after or outside the study timeline"@en ;
  rdfs:subClassOf obo:OBI_0000202 .

obo:OBI_0002195 a rdfs:Class ;
  rdfs:label "microtome blade" ;
  rdfs:comment "A device that is the part of a microtome used to slice specimens to a desired thickness." ;
  rdfs:subClassOf obo:OBI_0000968 .

obo:GEO_000000006 a rdfs:Class ;
  rdfs:label "geopolitical dependency"@en ;
  rdfs:comment "A subnational entity that does not possess full political independence or sovereignty as a sovereign state, but remains politically outside of the controlling state and controls a geographical region that is outside the controlling state's integral region."@en ;
  rdfs:subClassOf obo:GEO_000000004 .

obo:IAO_0020015 a rdfs:Class ;
  rdfs:label "personal name"@en ;
  rdfs:comment "A personal name is a proper name identifying an individual person."@en ;
  rdfs:subClassOf obo:IAO_0020000 .

obo:OBIB_0000656 a rdfs:Class ;
  rdfs:label "biobank location ISO 3166-1 alpha-2 code"@en ;
  rdfs:comment "An ISO 3166-1 alpha-2 code that designates the country a biobank is located in."@en ;
  rdfs:subClassOf obo:OBIB_0000620 .

obo:OBIB_0000546 a rdfs:Class ;
  rdfs:label "clinical history of high unexplained fever" ;
  rdfs:comment "A clinical history in which there is a history of a high unexplained fever ." ;
  rdfs:subClassOf obo:OGMS_0000015 .

obo:APOLLO_SV_00000085 a rdfs:Class ;
  rdfs:label "age data in age brackets data set"@en ;
  rdfs:comment "A data set consisting of measurements of age organized in age brackets." ;
  rdfs:subClassOf obo:IAO_0000100 .

obo:IAO_8000015 a rdfs:Class ;
  rdfs:label "template generated ontology module"@en ;
  rdfs:comment "An ontology module that is automatically generated from a template specification and fillers for slots in that template."@en ;
  rdfs:seeAlso <http://robot.obolibrary.org/template> , <https://github.com/dosumis/dead_simple_owl_design_patterns/> , <https://doi.org/10.1186/s13326-017-0126-0> ;
  rdfs:subClassOf obo:IAO_8000014 .

obo:FMA_24980 a rdfs:Class ;
  rdfs:label "Right leg" ;
  rdfs:subClassOf obo:UBERON_0000465 .

obo:OBIB_0000161 a rdfs:Class ;
  rdfs:label "pelvic mass excision" ;
  rdfs:comment "A surgical procedure to remove a mass (growth or tumor) on the ovary or in the pelvis." ;
  rdfs:subClassOf obo:OBIB_0000716 .

obo:OBIB_0000690 a rdfs:Class ;
  rdfs:label "omics experiment on specimen"@en ;
  rdfs:comment "An objective specification that aims at the collective characterization and quantification of pools of biological molecules that translate into the structure, function, and dynamics of an organism or organisms."@en ;
  rdfs:subClassOf obo:OBI_0000471 .

obo:OBIB_0000359 a rdfs:Class ;
  rdfs:label "time specimen place in stabilizer" ;
  rdfs:comment "A data item indicating the time when a specimen was placed in a container with stabilizing reagent." ;
  rdfs:subClassOf obo:IAO_0000027 .

obo:IAO_0000408 a rdfs:Class ;
  rdfs:label "length measurement datum"@en ;
  rdfs:comment "A scalar measurement datum that is the result of measurement of length quality"@en ;
  rdfs:subClassOf obo:IAO_0000032 .

obo:OBIB_0000525 a rdfs:Class ;
  rdfs:label "vaginal ring-based hormonal birth control method" ;
  rdfs:comment "A birth control method that involves the administration of hormones through a vaginal ring." ;
  rdfs:subClassOf obo:NCIT_C106501 .

obo:OBIB_0000237 a rdfs:Class ;
  rdfs:label "fresh venous needle blood specimen collection" ;
  rdfs:comment "A blood specimen collection that is performed with a fresh needle inserted into a vein." ;
  rdfs:subClassOf obo:OBIB_0000231 .

obo:OBIB_0000650 a rdfs:Class ;
  rdfs:label "name of sample collection responsible or principal investigator"@en ;
  rdfs:comment "A personal name that designates the human being responsible for a sample collection or the human being being the principal investigator in a study."@en ;
  rdfs:subClassOf obo:IAO_0020015 .

obo:OBI_0302908 a rdfs:Class ;
  rdfs:label "document editing"@en ;
  rdfs:comment "is a planned process with specified input original document and specified output edited document"@en ;
  rdfs:subClassOf obo:OBI_0000011 .

obo:OBIB_0000406 a rdfs:Class ;
  rdfs:label "FFPE slide consistent with findings of diagnostic pathology report" ;
  rdfs:comment "An information content entity that is an indicator of whether a formalin-fixed paraffin-embedded (FFPE) slide was consistent with findings of diagnostic pathology report." ;
  rdfs:subClassOf obo:IAO_0000030 .

obo:PATO_0000146 a rdfs:Class ;
  rdfs:label "temperature" ;
  rdfs:comment "A physical quality of the thermal energy of a system." ;
  rdfs:subClassOf obo:PATO_0001018 .

obo:OBI_0002413 a rdfs:Class ;
  rdfs:label "perimenopausal status" ;
  rdfs:comment "A menopausal status indicating that it has been 6-12 months since last menstrual period." ;
  rdfs:subClassOf obo:OBI_0002410 .

obo:BFO_0000018 a rdfs:Class ;
  rdfs:label "zero-dimensional spatial region"@en ;
  rdfs:subClassOf obo:BFO_0000006 .

obo:OBIB_0000098 a rdfs:Class ;
  rdfs:label "indeterminate serological assay result" ;
  rdfs:comment "A data item that indicates the amount of a serum analyte is approximately at a threshold considered to be present and therefore can not be confidently scored as positive or negative." ;
  rdfs:subClassOf obo:IAO_0000027 .

obo:OBIB_0002003 a rdfs:Class ;
  rdfs:label "specimen slide ID"@en ;
  rdfs:comment "An identifier that specifically identifies a particular specimen slide." ;
  rdfs:subClassOf obo:IAO_0020000 .

obo:NCIT_C29719 a rdfs:Class ;
  rdfs:label "Tobacco Smoking History" ;
  rdfs:comment "A record of an individual's background in regard to smoking tobacco. This would include such factors as start date, end date (if applicable), number of cigarette smoked, attempts to quit, and others." ;
  rdfs:subClassOf obo:IAO_0000030 .

obo:OBIB_0000568 a rdfs:Class ;
  rdfs:label "clinical history of exposure to rabies" ;
  rdfs:comment "A clinical history in which there is a history of an animal bite in recent past, from an animal suspected to have rabies." ;
  rdfs:subClassOf obo:OGMS_0000015 .

obo:OBIB_0000419 a rdfs:Class ;
  rdfs:label "name of performer of gross evaluation of resected tissue specimen" ;
  rdfs:comment "A personal name that designates the person who performed the gross evaluation of a resected tissue specimen." ;
  rdfs:subClassOf obo:IAO_0020015 .

obo:CHEBI_52993 a rdfs:Class ;
  rdfs:label "lormetazepam" ;
  rdfs:comment "A 1,4-benzodiazepinone compound having a methyl substituent at the 1-position, a hydroxy substituent at the 3-position, a 2-chlorophenyl group at the 5-position and a chloro substituent at the 7-position." ;
  rdfs:subClassOf obo:CHEBI_23367 .

obo:OBI_0100051 a rdfs:Class ;
  rdfs:label "specimen"@en ;
  rdfs:comment "A material entity that has the specimen role."@en ;
  rdfs:subClassOf obo:BFO_0000040 .

obo:OBIB_0000664 a rdfs:Class ;
  rdfs:label "frozen tissue block specimen"@en ;
  rdfs:comment "A frozen specimen is a tissue sample preserved in a block."@en ;
  rdfs:subClassOf obo:OBI_0000922 .

obo:OBIB_0000577 a rdfs:Class ;
  rdfs:label "clinical history of night sweats" ;
  rdfs:comment "A clinical history in which there is a history of night sweats." ;
  rdfs:subClassOf obo:OGMS_0000015 .

obo:OMIABIS_0001048 a rdfs:Class ;
  rdfs:label "obsolete specimen measurement specification" ;
  rdfs:subClassOf <http://www.geneontology.org/formats/oboInOwl#ObsoleteClass> .

obo:OMIABIS_0000093 a rdfs:Class ;
  rdfs:label "obsolete biobank contact role" ;
  rdfs:subClassOf <http://www.geneontology.org/formats/oboInOwl#ObsoleteClass> .

obo:OBI_0000456 a rdfs:Class ;
  rdfs:label "material transformation objective"@en ;
  rdfs:comment "an objective specifiction that creates an specific output object from input materials."@en ;
  rdfs:subClassOf obo:IAO_0000005 .

obo:OBIB_0000167 a rdfs:Class ;
  rdfs:label "vaginal surgical method" ;
  rdfs:comment "A surgical method in which operations are performed through the vagina." ;
  rdfs:subClassOf obo:OBIB_0000165 .

obo:OBIB_0000190 a rdfs:Class ;
  rdfs:label "left pneumonectomy" ;
  rdfs:comment "A surgical procedure performed to remove an entire left lung" ;
  rdfs:subClassOf obo:OBIB_0000716 .

obo:OBI_0002383 a rdfs:Class ;
  rdfs:label "nephew clinical history of cancer" ;
  rdfs:comment "A clinical history in which there is a diagnosis of cancer in a male child of a sibling." ;
  rdfs:subClassOf obo:OBI_0002372 .

obo:UBERON_0000316 a rdfs:Class ;
  rdfs:label "cervical mucus" ;
  rdfs:comment "A substance produced by the cervix and endocervical glands[BTO]. Thick acidic mucus that blocks the cervical os after mestruation[WP]. This 'infertile' mucus blocks spermatozoa from entering the uterus." ;
  rdfs:subClassOf obo:UBERON_0006314 .

obo:OBI_0000372 a rdfs:Class ;
  rdfs:label "material separation function"@en ;
  rdfs:comment "A material separation function is a function that increases the resolution between two or more material entities. The  to distinction between the entities is usually based on some associated physical quality."@en ;
  rdfs:subClassOf obo:BFO_0000034 .

obo:UBERON_0035840 a rdfs:Class ;
  rdfs:label "esophagogastric junction muscularis mucosa" ;
  rdfs:comment "Muscularis mucosa from the lowest portion of the esophagus, just proximal to the stomach." ;
  rdfs:subClassOf obo:UBERON_0000064 .

obo:OBIB_0000019 a rdfs:Class ;
  rdfs:label "filled patient questionnaire"@en ;
  rdfs:comment "A patient questionnaire which has been filled out by a patient." ;
  rdfs:subClassOf obo:OBIB_0000020 .

obo:CHEBI_18723 a rdfs:Class ;
  rdfs:label "nicotine" ;
  rdfs:comment "A racemate composed of equimolar amounts of (R)- and (S)-nicotine." ;
  rdfs:subClassOf obo:CHEBI_23367 .

obo:OBI_0002401 a rdfs:Class ;
  rdfs:label "hormonal birth control use history" ;
  rdfs:comment "An information content entity that indicates whether a woman has ever used oral contraceptives in order to block ovulation and prevent the occurrence of pregnancy." ;
  rdfs:subClassOf obo:IAO_0000030 .

obo:OBIB_0000512 a rdfs:Class ;
  rdfs:label "lifelong non-smoker history" ;
  rdfs:comment "A Smoking History in which there was no or an insignificant level of smoking." ;
  rdfs:subClassOf obo:NCIT_C29719 .

obo:OBIB_0000402 a rdfs:Class ;
  rdfs:label "confirmation of histologic type of FFPE H&E tumor slide" ;
  rdfs:comment "An information content entity that is an indicator of whether the local pathology review of a formalin-fixed paraffin-embedded (FFPE) hematoxylin and eosin (H&E)-stained tumor tissue slide confirmed the histological type." ;
  rdfs:subClassOf obo:IAO_0000030 .

obo:CHEBI_7907 a rdfs:Class ;
  rdfs:label "pancuronium" ;
  rdfs:comment "A steroid ester in which a 5alpha-androstane skeleton is C-3alpha- and C-17beta-disubstituted with acetoxy groups and 2beta- and 16beta-disubstituted with 1-methylpiperidinium-1-yl groups. It is a non-depolarizing curare-mimetic muscle relaxant." ;
  rdfs:subClassOf obo:CHEBI_23367 .

obo:NCIT_C77819 a rdfs:Class ;
  rdfs:label "Eastern European" ;
  rdfs:comment "Denotes a person having origins in any of the countries of Eastern Europe such as Czechoslovakia, Poland, Croatia, Hungary, Slovenia, Former Soviet Union, or Finland. It also includes persons who call themselves Gypsies from this region." ;
  rdfs:subClassOf obo:NCIT_C43851 .

obo:OBIB_0000658 a rdfs:Class ;
  rdfs:label "biobank identifier with ISO 3166-1 alpha-2 code and CTEP organization identifier"@en ;
  rdfs:comment "A biobank identifier that has both an ISO 3166-1 alpha-2 code and a CTEP organization code."@en ;
  rdfs:subClassOf obo:OBIB_0000621 .

obo:OBIB_0000148 a rdfs:Class ;
  rdfs:label "indicator of ascites fluid collection during surgery" ;
  rdfs:comment "An information content entity that is an indication of whether ascites fluid was collected from the specimen donor during organ excision." ;
  rdfs:subClassOf obo:IAO_0000030 .

obo:OMIABIS_0001045 a rdfs:Class ;
  rdfs:label "obsolete specimen freezing" ;
  rdfs:subClassOf <http://www.geneontology.org/formats/oboInOwl#ObsoleteClass> .

obo:OBI_0002614 a rdfs:Class ;
  rdfs:label "birth cohort study design" ;
  rdfs:comment "A cohort study design for which the subjects are followed from the time of birth usually including information about gestation and follow up." ;
  rdfs:subClassOf obo:OBI_0500000 .

obo:OBIB_0000545 a rdfs:Class ;
  rdfs:label "clinical history of open wounds" ;
  rdfs:comment "A clinical history in which there is a history of open wounds." ;
  rdfs:subClassOf obo:OGMS_0000015 .

obo:OBIB_0000707 a rdfs:Class ;
  rdfs:label "study subject survey data"@en ;
  rdfs:comment "A survey data for a specimen donor."@en ;
  rdfs:subClassOf obo:OBIB_0000667 .

obo:UBERON_0001233 a rdfs:Class ;
  rdfs:label "right adrenal gland" ;
  rdfs:comment "An adrenal gland that is in the right side of the abdomen." ;
  rdfs:subClassOf obo:UBERON_0002369 .

obo:OMIABIS_0001081 a rdfs:Class ;
  rdfs:label "obsolete start of sampling specimens for biobank" ;
  rdfs:subClassOf <http://www.geneontology.org/formats/oboInOwl#ObsoleteClass> .

obo:OMRSE_00000218 a rdfs:Class ;
  rdfs:label "OMB Native Hawaiian or other Pacific Islander identity information content entity"@en ;
  rdfs:comment "An OMB racial identity information content entity that is about some person's identifying as Native Hawaiian or other Pacific Islander, which is intended to mean having origins in any of the original peoples of Hawaii, Guam, Samoa, or other Pacific Islands."@en ;
  rdfs:subClassOf obo:OMRSE_00000214 .

obo:OBI_0500026 a rdfs:Class ;
  rdfs:label "eligibility criterion"@en ;
  rdfs:comment """an eligibility criterion (rule) is_a selection criterion which 
defines and states the requirements (positive or negative) for an entity to be considered as suitable for a given task or participation in a process."""@en ;
  rdfs:subClassOf obo:OBI_0001755 .

obo:OBIB_0000095 a rdfs:Class ;
  rdfs:label "cessation of cardiac activity death" ;
  rdfs:comment "A life-death temporal boundary marked by the natural cessation of cardiac activity." ;
  rdfs:subClassOf obo:UBERON_0035944 .

obo:CL_0001034 a rdfs:Class ;
  rdfs:label "cell in vitro" ;
  rdfs:comment "A cell that is maintained or propagated in a controlled artificial environment for use in an investigation." ;
  rdfs:subClassOf obo:CL_0000000 .

obo:ICO_0000046 a rdfs:Class ;
  rdfs:label "act of authorizing"@en ;
  rdfs:comment "A planned process of making the decision of the competent authorities in form of a letter, document, or verbal or electronic form, that confirms that somebody has permission to do something or be somewhere, e.g. to realize a given project."@en ;
  rdfs:subClassOf obo:OBI_0000011 .

obo:OBIB_0000018 a rdfs:Class ;
  rdfs:label "form filling"@en ;
  rdfs:comment "A document editing process in which one or more fields in a form are filled with related information, such as when answering a questionnare." ;
  rdfs:subClassOf obo:OBI_0302908 .

obo:BFO_0000140 a rdfs:Class ;
  rdfs:label "continuant fiat boundary"@en ;
  rdfs:comment "b is a continuant fiat boundary = Def. b is an immaterial entity that is of zero, one or two dimensions and does not include a spatial region as part. (axiom label in BFO2 Reference: [029-001])"@en ;
  rdfs:subClassOf obo:BFO_0000141 .

obo:OBI_0002386 a rdfs:Class ;
  rdfs:label "diagnosis of hepatitis B" ;
  rdfs:comment "A diagnosis of infectious disease caused by the hepatitis B virus." ;
  rdfs:subClassOf obo:OBI_0002385 .

obo:OBI_0002204 a rdfs:Class ;
  rdfs:label "pNX" ;
  rdfs:comment "A cannot be assessed determination of pathologic staging of lymph nodes." ;
  rdfs:subClassOf obo:OBI_0002200 .

obo:CHEBI_33697 a rdfs:Class ;
  rdfs:label "ribonucleic acid" ;
  rdfs:comment "High molecular weight, linear polymers, composed of nucleotides containing ribose and linked by phosphodiester bonds; RNA is central to the synthesis of proteins." ;
  rdfs:subClassOf obo:CHEBI_33839 .

obo:OBIB_0000145 a rdfs:Class ;
  rdfs:label "specimen donor intraoperative urine excreted volume measurement datum" ;
  rdfs:comment "A measurement datum of the volume of intraoperative urine excreted obtained from the specimen donor during surgery." ;
  rdfs:subClassOf obo:IAO_0000109 .

obo:NCIT_C5226 a rdfs:Class ;
  rdfs:label "Borderline Ovarian Serous Tumor" ;
  rdfs:comment "A low grade serous epithelial neoplasm arising from the ovary.  It is characterized by an atypical proliferation of serous-type epithelial cells without evidence of stromal invasion.  It is often asymptomatic but rarely it may present with abdominal pain or abdominal enlargement due to rupture or torsion." ;
  rdfs:subClassOf obo:DOID_0050933 .

obo:OBIB_0000669 a rdfs:Class ;
  rdfs:label "biobank contact role"@en ;
  rdfs:comment "A contact role borne by a member of a biobank organization and realized by serving as the contact for one of its biobanks."@en ;
  rdfs:subClassOf obo:OBIB_0000625 .

obo:OBIB_0000604 a rdfs:Class ;
  rdfs:label "indication of having resided in a Northern European military base" ;
  rdfs:comment "An information content entity in which there is an indication of whether an individual resided on a Northern European military base for a specified duration during a specific time frame." ;
  rdfs:subClassOf obo:IAO_0000030 .

obo:IDO_0000612 a rdfs:Class ;
  rdfs:label "pathologic immunosuppression"@en ;
  rdfs:comment "An immunosuppression process which arises as the result of a disorder."@en ;
  rdfs:subClassOf obo:IDO_0000610 .

obo:UBERON_0001087 a rdfs:Class ;
  rdfs:label "pleural fluid" ;
  rdfs:comment "Transudate contained in the pleural cavity." ;
  rdfs:subClassOf obo:UBERON_0006314 .

obo:OMIABIS_0001077 a rdfs:Class ;
  rdfs:label "obsolete saliva specimen" ;
  rdfs:subClassOf <http://www.geneontology.org/formats/oboInOwl#ObsoleteClass> .

obo:OMIABIS_0000023 a rdfs:Class ;
  rdfs:label "obsolete post-office box number" ;
  rdfs:subClassOf <http://www.geneontology.org/formats/oboInOwl#ObsoleteClass> .

obo:OBIB_0000001 a rdfs:Class ;
  rdfs:label "sample collection identifier"@en ;
  rdfs:comment "A proper name that refers to a sample collection."@en ;
  rdfs:subClassOf obo:IAO_0020000 .

obo:OBIB_0000616 a rdfs:Class ;
  rdfs:label "biobank"@en ;
  rdfs:comment """A biobank is a collections of samples of biological substances
(e.g. tissue, blood, DNA) which are linked to data about the samples and their donors. They have a dual nature as collections of samples and data."""@en ;
  rdfs:subClassOf obo:BFO_0000027 .

obo:OBI_0002419 a rdfs:Class ;
  rdfs:label "exposure to chromium history" ;
  rdfs:comment "An exposure to environmental and workplace carcinogens history where the carcinogen is chromium." ;
  rdfs:subClassOf obo:OBI_0002415 .

obo:UO_0000002 a rdfs:Class ;
  rdfs:label "mass unit" ;
  rdfs:subClassOf obo:IAO_0000003 .

obo:ICO_0000001 a rdfs:Class ;
  rdfs:label "informed consent form"@en ;
  rdfs:comment "A document that explains all relevant information to assist a human being in understanding the expectations and requirements of participation in a process, and is an instrument in obtaining consent and, after having obtained consent, is a record that such a consent has occurred."@en ;
  rdfs:subClassOf obo:IAO_0000310 .

obo:OBI_0002532 a rdfs:Class ;
  rdfs:label "esophagus mucosa specimen" ;
  rdfs:comment "A specimen that is derived from esophagus mucosa." ;
  rdfs:subClassOf obo:OBI_0001479 .

obo:HANCESTRO_0568 a rdfs:Class ;
  rdfs:label "African American" ;
  rdfs:subClassOf obo:HANCESTRO_0463 .

obo:OBI_0002379 a rdfs:Class ;
  rdfs:label "son clinical history of cancer" ;
  rdfs:comment "A clinical history in which there is a diagnosis of cancer in a person's male child." ;
  rdfs:subClassOf obo:OBI_0002372 .

obo:OBI_0002563 a rdfs:Class ;
  rdfs:label "ethnicity inclusion criterion"@en ;
  rdfs:comment "An inclusion criteria that defines and states one or more ethnicities which, if met, makes an entity suitable for a given task or participation in a given process."@en ;
  rdfs:subClassOf obo:OBI_0500027 .

obo:OBIB_0000361 a rdfs:Class ;
  rdfs:label "data and time specimen was frozen in liquid nitrogen" ;
  rdfs:comment "A data item indicating the date and time at which a specimen was frozen by placement in liguid nitrogen." ;
  rdfs:subClassOf obo:IAO_0000027 .

obo:OBI_0600005 a rdfs:Class ;
  rdfs:label "collecting specimen from organism"@en ;
  rdfs:comment "a process with the objective to obtain a material entity that was part of an organism for potential future use in an investigation"@en ;
  rdfs:subClassOf obo:OBI_0000659 .

obo:OBI_0002547 a rdfs:Class ;
  rdfs:label "minor salivary gland specimen" ;
  rdfs:comment "A specimen that is derived from minor salivary gland." ;
  rdfs:subClassOf obo:OBI_0001479 .

obo:OMIABIS_0000012 a rdfs:Class ;
  rdfs:label "obsolete contact role" ;
  rdfs:subClassOf <http://www.geneontology.org/formats/oboInOwl#ObsoleteClass> .

obo:PCO_0000000 a rdfs:Class ;
  rdfs:label "collection of organisms"@en ;
  rdfs:comment "A material entity that consists of two or more organisms, viruses, or viroids."@en ;
  rdfs:subClassOf obo:BFO_0000027 .

obo:OBIB_0000321 a rdfs:Class ;
  rdfs:label "fresh microtome blade" ;
  rdfs:comment "A microtome blade age that indicates that the microtome blade is as new as possible." ;
  rdfs:subClassOf obo:OBIB_0000320 .

obo:FMA_50707 a rdfs:Class ;
  rdfs:label "Anatomical location" ;
  rdfs:comment "Spatial association relationship which describes the containment, adjacency and anatomical coordinates of physical anatomical entities. Examples: anatomical containment, anatomical adjacency, anatomical coordinate." ;
  rdfs:subClassOf obo:BFO_0000141 .

obo:NCIT_C15477 a rdfs:Class ;
  rdfs:label "Prior Radiation Therapy" ;
  rdfs:comment "An indicator that a person previously received radiation treatment for the same condition." ;
  rdfs:subClassOf obo:OGMS_0000090 .

obo:UBERON_0022277 a rdfs:Class ;
  rdfs:label "hepatic flexure of colon" ;
  rdfs:comment "Hepatic (or the right colic) flexure is the sharp bend between the ascending and the transverse colon. The right colic flexure is adjacent to the liver, and is therefore also known as the hepatic flexure. Thus, the left colic flexure is also known as the splenic flexure (as it is close to the spleen). The hepatic flexure lies in the right upper quadrant of the abdomen in humans." ;
  rdfs:subClassOf obo:UBERON_0000064 .

obo:OBIB_0000097 a rdfs:Class ;
  rdfs:label "negative serological assay result" ;
  rdfs:comment "A data item that indicates the amount of a serum analyte is at a level below a threshold considered to be present." ;
  rdfs:subClassOf obo:IAO_0000027 .

obo:OBI_0002124 a rdfs:Class ;
  rdfs:label "H&E slide staining"@en ;
  rdfs:comment "A staining using hematoxylin and eosin. The staining is applied to fixed specimens on slides to observe the whole structure and morphology of cells in a tissue; nuclei are stained dark blue/purple while cytoplasm is stained pink."@en ;
  rdfs:subClassOf obo:OBI_0302887 .

obo:OBIB_0000029 a rdfs:Class ;
  rdfs:label "medication material"@en ;
  rdfs:comment "A material entity that is bearer of a medication role." ;
  rdfs:subClassOf obo:BFO_0000040 .

obo:OBI_0000319 a rdfs:Class ;
  rdfs:label "material to be added role"@en ;
  rdfs:comment "A role of a material entity that is realized in an \"adding a material entity into a target\" process where the bearer of the role is added into another material entity (the target)."@en ;
  rdfs:subClassOf obo:BFO_0000023 .

obo:UBERON_0002037 a rdfs:Class ;
  rdfs:label "cerebellum" ;
  rdfs:comment "Part of the metencephalon that lies in the posterior cranial fossa behind the brain stem. It is concerned with the coordination of movement[MESH]. A large dorsally projecting part of the brain concerned especially with the coordination of muscles and the maintenance of bodily equilibrium, situated between the brain stem and the back of the cerebrum , and formed in humans of two lateral lobes and a median lobe[BTO]. Brain structure derived from the anterior hindbrain, and perhaps including posterior midbrain. The cerebellum plays a role in somatic motor function, the control of muscle tone, and balance[ZFA]." ;
  rdfs:subClassOf obo:UBERON_0000481 .

obo:OBIB_0000563 a rdfs:Class ;
  rdfs:label "clinical history of long term steroid use" ;
  rdfs:comment "A clinical history in which there is a history of long term steroid use." ;
  rdfs:subClassOf obo:OGMS_0000015 .

obo:IAO_8000020 a rdfs:Class ;
  rdfs:label "EL++ ontology module"@en ;
  rdfs:subClassOf obo:IAO_8000019 .

obo:OMRSE_00000213 a rdfs:Class ;
  rdfs:label "racial identity information content entity"@en ;
  rdfs:comment "A social identity information content entity that is about whether some person identifies as some race."@en ;
  rdfs:subClassOf obo:OMRSE_00000204 .

obo:IDO_0000450 a rdfs:Class ;
  rdfs:label "pathogenic disposition"@en ;
  rdfs:comment "A disposition to initiate processes that result in a disorder."@en ;
  rdfs:subClassOf obo:BFO_0000016 .

obo:OBI_0000257 a rdfs:Class ;
  rdfs:label "DNA extraction"@en ;
  rdfs:comment "A DNA extraction is a nucleic acid extraction where the desired output material is DNA."@en ;
  rdfs:subClassOf obo:OBI_0666667 .

obo:OBIB_0000102 a rdfs:Class ;
  rdfs:label "preoperative intravenous administration of opioid analgesic" ;
  rdfs:comment "A planned process to administer opioid analgesics intravenously prior to surgery in order to induce total or partial loss of sensation especially tactile sensation and pain." ;
  rdfs:subClassOf obo:OBI_0000011 .

obo:IAO_0000140 a rdfs:Class ;
  rdfs:label "setting datum"@en ;
  rdfs:comment "A settings datum is a datum that denotes some configuration of an instrument."@en ;
  rdfs:subClassOf obo:IAO_0000027 .

obo:OMIABIS_0001034 a rdfs:Class ;
  rdfs:label "obsolete sample collection data update" ;
  rdfs:subClassOf <http://www.geneontology.org/formats/oboInOwl#ObsoleteClass> .

obo:OBIB_0000326 a rdfs:Class ;
  rdfs:label "FFPE water bath temperature" ;
  rdfs:comment "A scalar measurement datum that is the output of a temperature measurement assay performed on a water bath used in a formalin-fixed paraffin-embedded (FFPE) process." ;
  rdfs:subClassOf obo:IAO_0000032 .

obo:OBI_0000652 a rdfs:Class ;
  rdfs:label "material combination" ;
  rdfs:comment "is a material processing with the objective to combine two or more material entities as input into a single material entity as output." ;
  rdfs:subClassOf obo:OBI_0000094 .

obo:OBI_0002141 a rdfs:Class ;
  rdfs:label "volume measurement assay" ;
  rdfs:comment "An assay to determine the volume of an evaluant." ;
  rdfs:subClassOf obo:OBI_0000070 .

obo:OBIB_0000579 a rdfs:Class ;
  rdfs:label "clinical history of unexplained lymphadenopathy" ;
  rdfs:comment "A clinical history in which there is a history of unexplained lymphadenopathy of a specific duration." ;
  rdfs:subClassOf obo:OGMS_0000015 .

obo:OBI_0002542 a rdfs:Class ;
  rdfs:label "aorta specimen" ;
  rdfs:comment "A specimen that is derived from aorta." ;
  rdfs:subClassOf obo:OBI_0001479 .

obo:OBIB_0000534 a rdfs:Class ;
  rdfs:label "high meat diet colorectal cancer risk factor" ;
  rdfs:comment "A colorectal cancer risk factor that is having a diet that is high in red meats and processed meats." ;
  rdfs:subClassOf obo:OBIB_0000533 .

obo:OBIB_0000395 a rdfs:Class ;
  rdfs:label "percentage of cross-sectional surface area of entire slide composed of necrotic tissue" ;
  rdfs:comment "A data item that is the result of determining the percentage of cross-sectional surface area of an entire specimen slide that is composed of necrotic tissue." ;
  rdfs:subClassOf obo:IAO_0000027 .

obo:OBIB_0000653 a rdfs:Class ;
  rdfs:label "street"@en ;
  rdfs:comment "A street is a  thoroughfare in a built environment."@en ;
  rdfs:subClassOf obo:BFO_0000040 .

obo:OMIABIS_0000041 a rdfs:Class ;
  rdfs:label "obsolete street" ;
  rdfs:subClassOf <http://www.geneontology.org/formats/oboInOwl#ObsoleteClass> .

obo:OBI_0002148 a rdfs:Class ;
  rdfs:label "surface HBV antibody assay" ;
  rdfs:comment "An antigen specific antibodies assay that is meant to detect antibodies that bind to hepatitis B virus (HBV) surface antigens." ;
  rdfs:subClassOf obo:OBI_0002145 .

obo:UBERON_0006911 a rdfs:Class ;
  rdfs:label "digestive system secreted substance" ;
  rdfs:subClassOf obo:UBERON_0000463 .

obo:OBI_0002372 a rdfs:Class ;
  rdfs:label "family clinical history of cancer" ;
  rdfs:comment "A clinical history in which there is a diagnosis of cancer in a blood relative." ;
  rdfs:subClassOf obo:OGMS_0000015 .

obo:OBIB_0000172 a rdfs:Class ;
  rdfs:label "indicator of pelvic washings collected during ovarian surgery" ;
  rdfs:comment "An information content entity that is an indication of whether pelvic washings were collected during ovarian surgery." ;
  rdfs:subClassOf obo:IAO_0000030 .

obo:OMIABIS_0000100 a rdfs:Class ;
  rdfs:label "obsolete study principle investigator or responsible" ;
  rdfs:subClassOf <http://www.geneontology.org/formats/oboInOwl#ObsoleteClass> .

obo:OBIB_0000291 a rdfs:Class ;
  rdfs:label "FFPE clearing agent role" ;
  rdfs:comment "A role borne by a chemical that is realized in the formalin-fixed paraffin-embedded (FFPE) processes to remove alcohol used for specimen dehydration, remove stains, and prepare a specimen for infiltration medium." ;
  rdfs:subClassOf obo:BFO_0000023 .

obo:OBI_0002159 a rdfs:Class ;
  rdfs:label "HCV nucleic acid testing" ;
  rdfs:comment "An analyte assay that is meant to detect hepatitis C virus (HCV) nucleic acids." ;
  rdfs:subClassOf obo:OBI_0000443 .

obo:OGMS_0000015 a rdfs:Class ;
  rdfs:label "clinical history" ;
  rdfs:comment "A series of statements representing health-relevant qualities of a patient and of a patient's family."@en ;
  rdfs:subClassOf obo:IAO_0000030 .

obo:OBIB_0000310 a rdfs:Class ;
  rdfs:label "FFPE paraffin processing for embedding temperature" ;
  rdfs:comment "A scalar measurement datum that is the output of a temperature measurement assay performed during the paraffin processing for embedding in a formalin-fixed paraffin-embedded (FFPE) process." ;
  rdfs:subClassOf obo:IAO_0000032 .

obo:UBERON_0001836 a rdfs:Class ;
  rdfs:label "saliva" ;
  rdfs:comment "A fluid produced in the oral cavity by salivary glands, typically used in predigestion, but also in other functions." ;
  rdfs:subClassOf obo:UBERON_0000463 .

obo:OBIB_0000539 a rdfs:Class ;
  rdfs:label "estrogen alone hormone replacement therapy" ;
  rdfs:comment "A hormone replacement therapy where the hormone is estrogen." ;
  rdfs:subClassOf <http://www.ebi.ac.uk/efo/EFO_0003961> .

obo:OBI_0002414 a rdfs:Class ;
  rdfs:label "postmenopausal status" ;
  rdfs:comment "A menopausal status indicating that it has been more than 12 months since the last menstrual period with no prior hysterectomy or that there has been a prior bilateral oophorectomy." ;
  rdfs:subClassOf obo:OBI_0002410 .

obo:OBIB_0000209 a rdfs:Class ;
  rdfs:label "specimen gross appearance of tumor" ;
  rdfs:comment "A specimen gross appearance of a tumor manifestation." ;
  rdfs:subClassOf obo:OBIB_0000208 .

obo:OBIB_0000350 a rdfs:Class ;
  rdfs:label "manager of human research protocol requirements role" ;
  rdfs:comment "A role borne by personnel responsible for managing human research protocol requirements including but not limited to screening, obtaining authorization, consenting and/or enrollment activities." ;
  rdfs:subClassOf obo:BFO_0000023 .

obo:OBI_0600016 a rdfs:Class ;
  rdfs:label "pooling specimens"@en ;
  rdfs:comment "physical combination of several instances of like material"@en ;
  rdfs:subClassOf obo:OBI_0000652 .

obo:UBERON_0001153 a rdfs:Class ;
  rdfs:label "caecum" ;
  rdfs:comment "A pouch in the digestive tract that connects the ileum with the ascending colon of the large intestine. It is separated from the ileum by the ileocecal valve, and is the beginning of the large intestine. It is also separated from the colon by the cecocolic junction." ;
  rdfs:subClassOf obo:UBERON_0000064 .

obo:OBI_0002617 a rdfs:Class ;
  rdfs:label "national registry"@en ;
  rdfs:comment "An information content entity that contains information about a nationwide group of individuals." ;
  rdfs:subClassOf obo:IAO_0000030 .

obo:OBIB_0000137 a rdfs:Class ;
  rdfs:label "carbon dioxide level of specimen donor recorded at time closest to organ excision" ;
  rdfs:comment "A measurement datum of the level of carbon dioxide gas at time closest to organ exiscion from the specimen donor." ;
  rdfs:subClassOf obo:IAO_0000109 .

obo:OBIB_0000390 a rdfs:Class ;
  rdfs:label "date of review of pathology case summary report" ;
  rdfs:comment "A data item that reports the calendar date when a pathology case summary report was reviewed." ;
  rdfs:subClassOf obo:IAO_0000027 .

obo:BFO_0000031 a rdfs:Class ;
  rdfs:label "generically dependent continuant"@en ;
  rdfs:comment "A continuant that is dependent on one or other independent continuant bearers. For every instance of A requires some instance of (an independent continuant type) B but which instance of B serves can change from time to time."@en ;
  rdfs:subClassOf obo:BFO_0000002 .

obo:OBIB_0000315 a rdfs:Class ;
  rdfs:label "adherence to FFPE tissue block storage SOP" ;
  rdfs:comment "An information content entity that indicates whether the FFPE tissue block storage SOP was followed." ;
  rdfs:subClassOf obo:IAO_0000030 .

obo:OBI_0000067 a rdfs:Class ;
  rdfs:label "evaluant role"@en ;
  rdfs:comment "a role that inheres in a material entity that is realized in an assay in which data is generated about the bearer of the evaluant role"@en ;
  rdfs:subClassOf obo:OMRSE_00000048 .

obo:OBIB_0000722 a rdfs:Class ;
  rdfs:label "case ID"@en ;
  rdfs:comment "An identifier that refers to a specimen donor who is participating in specimen collection process for tissue procurement purposes and is usually assigned at the time of donor procurement."@en ;
  rdfs:subClassOf obo:IAO_0020000 .

obo:IAO_0000579 a rdfs:Class ;
  rdfs:label "centrally registered identifier registry"@en ;
  rdfs:comment "A code set of CRID records, each consisting of a CRID symbol and additional information which was recorded in the code set through an assigning a centrally registered identifier process."@en ;
  rdfs:subClassOf obo:IAO_0000100 .

obo:IAO_0000005 a rdfs:Class ;
  rdfs:label "objective specification"@en ;
  rdfs:comment "A directive information entity that describes an intended process endpoint. When part of a plan specification the concretization is realized in a planned process in which the bearer tries to effect the world so that the process endpoint is achieved."@en ;
  rdfs:subClassOf obo:IAO_0000033 .

obo:OBI_2000017 a rdfs:Class ;
  rdfs:label "reticulocyte specimen" ;
  rdfs:comment "A specimen that is derived from some reticulocytes" ;
  rdfs:subClassOf obo:OBI_0002599 .

obo:OBI_0200000 a rdfs:Class ;
  rdfs:label "data transformation"@en ;
  rdfs:comment "A planned process that produces output data from input data."@en ;
  rdfs:subClassOf obo:OBI_0000011 .

obo:OBIB_0000232 a rdfs:Class ;
  rdfs:label "name of person performing blood draw" ;
  rdfs:comment "A personal name that designates the person who performed the collection of a blood specimen." ;
  rdfs:subClassOf obo:IAO_0020015 .

obo:OMIABIS_0001004 a rdfs:Class ;
  rdfs:label "obsolete date of data entry" ;
  rdfs:subClassOf <http://www.geneontology.org/formats/oboInOwl#ObsoleteClass> .

obo:OBIB_0000295 a rdfs:Class ;
  rdfs:label "FFPE dehydration process duration" ;
  rdfs:comment "A time measurement datum that is the result of measuring the duration of the dehydration process in the formalin-fixed paraffin-embedded (FFPE) process." ;
  rdfs:subClassOf obo:IAO_0000416 .

obo:OBIB_0000496 a rdfs:Class ;
  rdfs:label "presence of a tumor larger than a specified size exclusion criterion" ;
  rdfs:comment "An exclusion criterion that defines whether a tumor is larger than a specified size, which if met, makes an individual unsuitable for a given task or participation in a given process." ;
  rdfs:subClassOf obo:OBI_0500028 .

obo:BFO_0000144 a rdfs:Class ;
  rdfs:label "process profile"@en ;
  rdfs:comment "b is a process_profile =Def. there is some process c such that b process_profile_of c (axiom label in BFO2 Reference: [093-002])"@en ;
  rdfs:subClassOf obo:BFO_0000015 .

obo:OBIB_0000124 a rdfs:Class ;
  rdfs:label "transverse colectomy" ;
  rdfs:comment "A colectomy that is resection of the transverse colon along with the middle colic vessels and its mesentery." ;
  rdfs:subClassOf obo:OAE_0001159 .

obo:CHEBI_17045 a rdfs:Class ;
  rdfs:label "dinitrogen oxide" ;
  rdfs:comment "A nitrogen oxide consisting of linear unsymmetrical molecules with formula N2O. While it is the most used gaseous anaesthetic in the world, its major commercial use, due to its solubility under pressure in vegetable fats combined with its non-toxicity in low concentrations, is as an aerosol spray propellant and aerating agent for canisters of 'whipped' cream." ;
  rdfs:subClassOf obo:CHEBI_23367 .

obo:OBI_0001472 a rdfs:Class ;
  rdfs:label "specimen with known storage state"@en ;
  rdfs:comment "A specimen for which it is known whether it has been subjected to storage of a specified type." ;
  rdfs:subClassOf obo:OBI_0100051 .

obo:OBIB_0000304 a rdfs:Class ;
  rdfs:label "adherence to paraffin impregnation method in FFPE tissue processing SOP" ;
  rdfs:comment "An information content entity that indicates whether the paraffin impregnation method followed that prescribed in the FFPE tissue processing SOP." ;
  rdfs:subClassOf obo:IAO_0000030 .

obo:OBIB_0000384 a rdfs:Class ;
  rdfs:label "comment on procurement site restriction" ;
  rdfs:comment "A comment from tissue procurement made in regards to all non-consent issues related to or creating a limitation on tissues that can be procured including tissue type and reason for restriction." ;
  rdfs:subClassOf obo:OBIB_0000712 .

obo:OBIB_0000044 a rdfs:Class ;
  rdfs:label "cigarette"@en ;
  rdfs:comment "A processed material which is a small cylinder of finely cut tobacco leaves rolled in thin paper for smoking." ;
  rdfs:subClassOf obo:OBIB_0000048 , obo:OBIB_0000057 .

obo:UBERON_0001052 a rdfs:Class ;
  rdfs:label "rectum" ;
  rdfs:comment "The terminal portion of the intestinal tube, terminating with the anus." ;
  rdfs:subClassOf obo:UBERON_0000064 .

obo:UBERON_0000341 a rdfs:Class ;
  rdfs:label "throat" ;
  rdfs:comment "In anatomy, the throat is the anterior part of the neck, in front of the vertebral column. It consists of the pharynx and larynx. An important feature of the throat is the epiglottis, a flap which separates the esophagus from the trachea and prevents inhalation of food or drink. The throat contains various blood vessels, various pharyngeal muscles, the trachea (windpipe) and the esophagus. The hyoid bone and the clavicle are the only bones located in the throat of mammals. It is sometimes considered a synonym for fauces. [WP,unvetted]." ;
  rdfs:subClassOf obo:UBERON_0000465 .

<https://w3id.org/linkml/Any> a rdfs:Class ;
  rdfs:comment "An unconstrained type or object" .

obo:NCIT_C16175 a rdfs:Class ;
  rdfs:label "Prior Hormone Therapy" ;
  rdfs:comment "An indication that an individual has been previously treated with hormonal therapy." ;
  rdfs:subClassOf obo:OGMS_0000090 .

obo:UBERON_0002108 a rdfs:Class ;
  rdfs:label "small intestine" ;
  rdfs:comment "Subdivision of digestive tract that connects the stomach to the large intestine and is where much of the digestion and absorption of food takes place (with the exception of ruminants). The mammalian small intestine is long and coiled and can be differentiated histologically into: duodenum, jejunem, ileum[WP,cjm,Kardong]." ;
  rdfs:subClassOf obo:UBERON_0000064 .

obo:OBIB_0000221 a rdfs:Class ;
  rdfs:label "fresh buffered formalin condition" ;
  rdfs:comment "A buffered formalin condition by virtue of being newly prepared with formalin that has not been previously used." ;
  rdfs:subClassOf obo:OBIB_0000220 .

obo:OBI_0002137 a rdfs:Class ;
  rdfs:label "RNA Integrity Number value specification"@en ;
  rdfs:comment "A value specification that specifies the value of the RNA Integrity Number as a real value between 1 (most degraded) and 10 (most intact)." ;
  rdfs:subClassOf obo:OBI_0001933 .

obo:OBI_0002390 a rdfs:Class ;
  rdfs:label "exposure to second hand smoke" ;
  rdfs:comment "A clinical history in which there has been second hand exposure to tobacco smoking." ;
  rdfs:subClassOf obo:OGMS_0000015 .

obo:OMIABIS_0000015 a rdfs:Class ;
  rdfs:label "obsolete email address of biobank contact person" ;
  rdfs:subClassOf <http://www.geneontology.org/formats/oboInOwl#ObsoleteClass> .

obo:IAO_8000008 a rdfs:Class ;
  rdfs:label "analysis subset ontology module"@en ;
  rdfs:comment "An ontology module that is intended for usage in analysis or discovery applications."@en ;
  rdfs:subClassOf obo:IAO_8000006 .

obo:UBERON_0002369 a rdfs:Class ;
  rdfs:label "adrenal gland" ;
  rdfs:comment "Either of a pair of complex endocrine organs near the anterior medial border of the kidney consisting of a mesodermal cortex that produces glucocorticoid, mineralocorticoid, and androgenic hormones and an ectodermal medulla that produces epinephrine and norepinephrine[BTO]." ;
  rdfs:subClassOf obo:UBERON_0000465 .

obo:OMIABIS_0001041 a rdfs:Class ;
  rdfs:label "obsolete surgical procedure" ;
  rdfs:subClassOf <http://www.geneontology.org/formats/oboInOwl#ObsoleteClass> .

obo:OBI_0001169 a rdfs:Class ;
  rdfs:label "age since birth measurement datum"@en ;
  rdfs:comment "An age measurement datum that is the result of the measurement of the age of an organism since birth, the process of emergence and separation of offspring from the mother." ;
  rdfs:subClassOf obo:OBI_0001167 .

obo:OBI_0002406 a rdfs:Class ;
  rdfs:label "delivery form for hormonal replacement therapy" ;
  rdfs:comment "A processed material used for delivery of hormones in hormone replacement therapy." ;
  rdfs:subClassOf obo:OBI_0000047 .

obo:OMRSE_00000210 a rdfs:Class ;
  rdfs:label "female gender identity information content entity"@en ;
  rdfs:comment "A gender identity information content entity that is about some person's identifying as female in gender."@en ;
  rdfs:subClassOf obo:OMRSE_00000209 .

obo:BFO_0000147 a rdfs:Class ;
  rdfs:label "zero-dimensional continuant fiat boundary"@en ;
  rdfs:subClassOf obo:BFO_0000140 .

obo:OBI_0002744 a rdfs:Class ;
  rdfs:label "molecular label"@en ;
  rdfs:comment "A molecular reagent intended to associate with some molecular target to serve as a proxy for the presence, abundance, or location of this target in a detection of molecular label assay"@en ;
  rdfs:subClassOf obo:CHEBI_23367 , obo:OBI_0001879 .

obo:OBIB_0000508 a rdfs:Class ;
  rdfs:label "current non-drinker of alcohol" ;
  rdfs:comment "An Alcohol Use History in which there was alcohol consumption in the past but is currently a non-drinker of alcohol." ;
  rdfs:subClassOf obo:NCIT_C81229 .

obo:OBI_0000659 a rdfs:Class ;
  rdfs:label "specimen collection process" ;
  rdfs:comment "A planned process with the objective of collecting a specimen." ;
  rdfs:subClassOf obo:OBI_0000011 .

obo:OBIB_0000011 a rdfs:Class ;
  rdfs:label "discarding"@en ;
  rdfs:comment "A planned process that gets rid of a material that is no longer useful or desirable." ;
  rdfs:subClassOf obo:OBI_0000011 .

obo:UBERON_0004539 a rdfs:Class ;
  rdfs:label "right kidney" ;
  rdfs:comment "A kidney that is part of a right side of organism [Automatically generated definition]." ;
  rdfs:subClassOf obo:UBERON_0002113 .

obo:OBI_0002655 a rdfs:Class ;
  rdfs:label "fine needle aspiration biopsy" ;
  rdfs:comment "A biopsy that uses a thin needle to extract cells." ;
  rdfs:subClassOf obo:OBI_0002654 .

obo:OBIB_0000588 a rdfs:Class ;
  rdfs:label "clinical history of West Nile Virus exposure" ;
  rdfs:comment "A clinical history in which there is a history of contact with a human or animal who has West Nile Virus (WNV)." ;
  rdfs:subClassOf obo:OGMS_0000015 .

obo:OBIB_0000194 a rdfs:Class ;
  rdfs:label "indicator of collected and banked pre-operative blood specimens" ;
  rdfs:comment "An information content entity that is an indicator of whether pre-operative/pre-anesthesia blood samples were collected from the participant and were successfully banked in a biobank." ;
  rdfs:subClassOf obo:IAO_0000030 .

obo:OBI_0000679 a rdfs:Class ;
  rdfs:label "average value"@en ;
  rdfs:comment "A  data item that is produced as the output of an averaging data transformation and represents the average value of the input data."@en ;
  rdfs:subClassOf obo:IAO_0000027 .

obo:OBI_0002536 a rdfs:Class ;
  rdfs:label "cerebral cortex specimen" ;
  rdfs:comment "A specimen that is derived from cerebral cortex." ;
  rdfs:subClassOf obo:OBI_0001479 .

obo:IAO_0020000 a rdfs:Class ;
  rdfs:label "identifier"@en ;
  rdfs:comment "An information content entity that is the outcome of a dubbing process and is used to refer to one instance of entity shared by a group of people to refer to that individual entity."@en ;
  rdfs:subClassOf obo:IAO_0000030 .

obo:OMIABIS_0000004 a rdfs:Class ;
  rdfs:label "obsolete ISO 3166-1 alpha-2 code" ;
  rdfs:subClassOf <http://www.geneontology.org/formats/oboInOwl#ObsoleteClass> .

obo:OBIB_0000241 a rdfs:Class ;
  rdfs:label "temperature in lab when blood specimen was received" ;
  rdfs:comment "A scalar measurement datum that is the output of a temperature measurement assay occurring in a laboratory and performed when a blood specimen is received." ;
  rdfs:subClassOf obo:IAO_0000032 .

obo:ICO_0000024 a rdfs:Class ;
  rdfs:label "partially filled informed consent form"@en ;
  rdfs:comment "An informed consent form that has been partially filled with required contents."@en ;
  rdfs:subClassOf obo:ICO_0000001 .

obo:PATO_0001708 a rdfs:Class ;
  rdfs:label "1-D extent" ;
  rdfs:comment "A size quality inhering in an bearer by virtue of the bearer's extension in one dimension." ;
  rdfs:subClassOf obo:PATO_0000117 .

obo:OMIABIS_0000026 a rdfs:Class ;
  rdfs:label "obsolete postal code" ;
  rdfs:subClassOf <http://www.geneontology.org/formats/oboInOwl#ObsoleteClass> .

obo:OBIB_0000711 a rdfs:Class ;
  rdfs:label "temperature regulating"@en ;
  rdfs:comment "A planned process that aims to control or maintain the temperature of a material entity to a given or required measurement datum." ;
  rdfs:subClassOf obo:OBI_0000011 .

obo:NCIT_C45502 a rdfs:Class ;
  rdfs:label "Lung Squamous Cell Carcinoma, Papillary Variant" ;
  rdfs:comment "A morphologic variant of squamous cell lung carcinoma characterized by the presence of papillary structures." ;
  rdfs:subClassOf obo:DOID_3907 .

obo:NCBITaxon_10239 a rdfs:Class ;
  rdfs:label "Viruses" ;
  rdfs:subClassOf obo:OBI_0100026 .

obo:OBI_0002397 a rdfs:Class ;
  rdfs:label "gynecologic surgery history" ;
  rdfs:comment "A clinical history in which a woman has had gynecologic surgery in the past." ;
  rdfs:subClassOf obo:OGMS_0000015 .

obo:OMIABIS_0000038 a rdfs:Class ;
  rdfs:label "obsolete name of sample collection responsible or principal investigator" ;
  rdfs:subClassOf <http://www.geneontology.org/formats/oboInOwl#ObsoleteClass> .

obo:NCIT_C4509 a rdfs:Class ;
  rdfs:label "Ovarian Undifferentiated Carcinoma" ;
  rdfs:comment "An aggressive carcinoma arising from the ovary.  Most patients present with advanced disease.  Microscopically, it is characterized by significant cytologic atypia, increased mitotic activity, and necrosis.  The prognosis is usually poor." ;
  rdfs:subClassOf obo:DOID_2394 .

obo:OBI_0000873 a rdfs:Class ;
  rdfs:label "pre-mortem specimen" ;
  rdfs:comment "a specimen that was taken from a live organism" ;
  rdfs:subClassOf obo:OBI_0001506 .

obo:NCBITaxon_40674 a rdfs:Class ;
  rdfs:label "Mammalia" ;
  rdfs:subClassOf obo:NCBITaxon_32524 .

obo:OMIABIS_0001015 a rdfs:Class ;
  rdfs:label "obsolete number of sampled human study participants objective" ;
  rdfs:subClassOf <http://www.geneontology.org/formats/oboInOwl#ObsoleteClass> .

obo:OBI_0002524 a rdfs:Class ;
  rdfs:label "urinary bladder specimen" ;
  rdfs:comment "A specimen that is derived from urinary bladder." ;
  rdfs:subClassOf obo:OBI_0001479 .

obo:UBERON_0007109 a rdfs:Class ;
  rdfs:label "meconium" ;
  rdfs:comment "A dark greenish mass that accumulates in the bowel during fetal life and is discharged shortly after birth." ;
  rdfs:subClassOf obo:UBERON_0001988 .

obo:PATO_0000165 a rdfs:Class ;
  rdfs:label "time" ;
  rdfs:comment "A quality in which events occur in sequence." ;
  rdfs:subClassOf obo:PATO_0001018 .

obo:NCBITaxon_10358 a rdfs:Class ;
  rdfs:label "Cytomegalovirus" ;
  rdfs:subClassOf obo:NCBITaxon_10292 .

obo:IAO_0000027 a rdfs:Class ;
  rdfs:label "data item"@en ;
  rdfs:comment "An information content entity that is intended to be a truthful statement about something (modulo, e.g., measurement precision or other systematic errors) and is constructed/acquired by a method which reliably tends to produce (approximately) truthful statements."@en ;
  rdfs:subClassOf obo:IAO_0000030 .

obo:UBERON_0002119 a rdfs:Class ;
  rdfs:label "left ovary" ;
  rdfs:comment "An ovary that is part of a left side of organism [Automatically generated definition]." ;
  rdfs:subClassOf obo:UBERON_0000992 .

obo:BFO_0000024 a rdfs:Class ;
  rdfs:label "fiat object part"@en ;
  rdfs:subClassOf obo:BFO_0000040 .

obo:IAO_0020022 a rdfs:Class ;
  rdfs:label "documented identity"@en ;
  rdfs:comment "A documented identity is the aggregate of all data items about an entity.  Notice that a documented identity is not itself a document since a document is intended to be understood as a whole and data items about an individual are usually scattered across different documents."@en ;
  rdfs:subClassOf obo:IAO_0000030 .

obo:DOID_3910 a rdfs:Class .

obo:UBERON_0004648 a rdfs:Class ;
  rdfs:label "esophagus muscularis mucosa" ;
  rdfs:comment "A muscularis mucosa that is part of a esophagus." ;
  rdfs:subClassOf obo:UBERON_0000479 .

obo:NCBITaxon_2 a rdfs:Class ;
  rdfs:label "Bacteria" ;
  rdfs:subClassOf obo:OBI_0100026 .

obo:UBERON_0001119 a rdfs:Class ;
  rdfs:label "right lobe of thyroid gland" ;
  rdfs:comment "A lobe of thyroid gland that is in the right side of a thyroid gland." ;
  rdfs:subClassOf obo:UBERON_0000064 .

obo:OBI_0002076 a rdfs:Class ;
  rdfs:label "collection of specimens"@en ;
  rdfs:comment "A material entity that has two or more specimens as its parts."@en ;
  rdfs:subClassOf obo:BFO_0000040 .

obo:UBERON_0001255 a rdfs:Class ;
  rdfs:label "urinary bladder" ;
  rdfs:comment "Distensible musculomembranous organ situated in the anterior part of the pelvic cavity in which urine collects before excretion[MP]." ;
  rdfs:subClassOf obo:UBERON_0000465 .

obo:OBIB_0000400 a rdfs:Class ;
  rdfs:label "percentage of non-cellular component of tumor slide specimen by surface area" ;
  rdfs:comment "A data item that is the result of determining the percentage of a tumor slide specimen that is non-cellular based on surface area." ;
  rdfs:subClassOf obo:IAO_0000027 .

obo:OBIB_0000243 a rdfs:Class ;
  rdfs:label "vacutainer specimen barcode" ;
  rdfs:comment "A specimen barcode that is associated with a vacutainer." ;
  rdfs:subClassOf obo:FLU_0001019 .

obo:OBI_0002155 a rdfs:Class ;
  rdfs:label "venereal disease research laboratory test" ;
  rdfs:comment "An analyte assay that is meant to detect general antibodies that react with substances that are produced by cellular damage caused by Treponema pallidum indicating a syphilis infection. VDRL tests require a microscope and can be done on cerebrospinal fluid as well as blood." ;
  rdfs:subClassOf obo:OBI_0000443 .

obo:OBIB_0000082 a rdfs:Class ;
  rdfs:label "time of surgical ligature for specimen collection" ;
  rdfs:comment "A data item that reports the time of day when a clamp or ligature was applied to an organ for specimen collection." ;
  rdfs:subClassOf obo:IAO_0000027 .

obo:OBIB_0000230 a rdfs:Class ;
  rdfs:label "pre-operative blood specimen collection" ;
  rdfs:comment "A blood specimen collection that occurs pre-operatively or pre-anesthesia relative to surgery." ;
  rdfs:subClassOf obo:OBIB_0000231 .

obo:OBI_0002558 a rdfs:Class ;
  rdfs:label "use of medication inclusion criterion"@en ;
  rdfs:comment "An inclusion criterion that defines and states a a set of medications, which, if used by an entity, makes that entity suitable for a given task or participation in a given process."@en ;
  rdfs:subClassOf obo:OBI_0500027 .

obo:OBIB_0000480 a rdfs:Class ;
  rdfs:label "identifier for legally authorized representative" ;
  rdfs:comment "An identifier that uniquely identifies a particular legally authorized representative in a research study." ;
  rdfs:subClassOf obo:IAO_0020000 .

obo:OMIABIS_0001018 a rdfs:Class ;
  rdfs:label "obsolete cross sectional study design" ;
  rdfs:subClassOf <http://www.geneontology.org/formats/oboInOwl#ObsoleteClass> .

obo:NCBITaxon_32524 a rdfs:Class ;
  rdfs:label "Amniota" ;
  rdfs:subClassOf obo:NCBITaxon_32523 .

obo:OGMS_0000090 a rdfs:Class ;
  rdfs:label "treatment" ;
  rdfs:comment "A planned process whose completion is hypothesized by a health care provider to eliminate, prevent, or alleviate a disorder, the signs and symptoms of a disorder, or a pathological process"@en ;
  rdfs:subClassOf obo:OBI_0000011 .

obo:NCIT_C40037 a rdfs:Class ;
  rdfs:label "Borderline Ovarian Mucinous Tumor, Intestinal Type" ;
  rdfs:comment "A neoplasm of low malignant potential arising from the ovary.  It is characterized by the proliferation of neoplastic mucinous epithelial cells that resemble intestinal epithelial cells.  There is no evidence of stromal invasion." ;
  rdfs:subClassOf obo:DOID_6067 .

obo:OBI_0000097 a rdfs:Class ;
  rdfs:label "participant under investigation role"@en ;
  rdfs:comment "A role that is realized through the execution of a study design in which the bearer of the role participates and in which data about that bearer is collected." ;
  rdfs:subClassOf obo:BFO_0000023 .

obo:OBI_0001064 a rdfs:Class ;
  rdfs:label "automatic tissue processor" ;
  rdfs:comment "A device for processing histological tissue having a tissue carrier basket suspended from a turntable overlying a plurality of beakers suspended from a carrier plate. The turntable is raised, indexed, and lowered by a suitable driving mechanism to move the tissue basket sequentially through the beakers. Timers can each be programmed to control the movement of the turntable to provide various different cycles for processing the tissue. Some of the beakers are received in individual thermal baths to heat and control the temperature of the substances received in the beakers for treating the tissue." ;
  rdfs:subClassOf obo:OBI_0000968 .

obo:OBIB_0000440 a rdfs:Class ;
  rdfs:label "participant signed and dated informed consent form" ;
  rdfs:comment "An information content entity that is an indicator of whether the participant signed and dated a specified informed consent form." ;
  rdfs:subClassOf obo:IAO_0000030 .

obo:HANCESTRO_0590 a rdfs:Class ;
  rdfs:label "European American" ;
  rdfs:subClassOf obo:HANCESTRO_0463 .

obo:OBI_0002428 a rdfs:Class ;
  rdfs:label "BMI range inclusion criterion" ;
  rdfs:comment "An inclusion criterion that defines and states a Body Mass Index range, which if met, makes an individual suitable for a given task or participation in a given process." ;
  rdfs:subClassOf obo:OBI_0500027 .

obo:OBIB_0000210 a rdfs:Class ;
  rdfs:label "obsolete fine needle biopsy" ;
  rdfs:comment "A biopsy that uses a thin, hollow needle to draw cells from a body." ;
  rdfs:subClassOf <http://www.geneontology.org/formats/oboInOwl#ObsoleteClass> .

obo:IAO_0000310 a rdfs:Class ;
  rdfs:label "document"@en ;
  rdfs:comment "A collection of information content entities intended to be understood together as a whole"@en ;
  rdfs:subClassOf obo:IAO_0000030 .

obo:OBI_2000010 a rdfs:Class ;
  rdfs:label "chorionic villus specimen" ;
  rdfs:comment "A specimen that is derived from some chorionic villus" ;
  rdfs:subClassOf obo:OBI_0001479 .

obo:NCIT_C126303 a rdfs:Class ;
  rdfs:label "Tubulocystic Renal Cell Carcinoma" ;
  rdfs:comment "A rare, cytologically high grade carcinoma that arises from the renal parenchyma. It is characterized by the presence of prominently dilated cystic spaces in a bland, fibrotic stroma. The lining cells have large irregular nuclei with prominent nucleoli and abundant eosinophilic cytoplasm. Necrosis and mitotic figures are not present. It rarely metastasizes." ;
  rdfs:subClassOf obo:DOID_4451 .

obo:OBIB_0000156 a rdfs:Class ;
  rdfs:label "hysterectomy with right salpingo-oophorectomy" ;
  rdfs:comment "A surgical procedure with the removal of the uterus, cervix, right fallopian tube, and right ovary." ;
  rdfs:subClassOf obo:OBIB_0000716 .

obo:OMIABIS_0001050 a rdfs:Class ;
  rdfs:label "obsolete time of surgical removal of specimen" ;
  rdfs:subClassOf <http://www.geneontology.org/formats/oboInOwl#ObsoleteClass> .

obo:OMIABIS_0001023 a rdfs:Class ;
  rdfs:label "obsolete quality control study design" ;
  rdfs:subClassOf <http://www.geneontology.org/formats/oboInOwl#ObsoleteClass> .

obo:NCBITaxon_10292 a rdfs:Class ;
  rdfs:label "Herpesviridae" ;
  rdfs:subClassOf obo:NCBITaxon_10239 .

obo:OBI_0000086 a rdfs:Class ;
  rdfs:label "reagent role"@en ;
  rdfs:comment "A role inhering in a biological or chemical entity that is intended to be applied in a scientific technique to participate (or have molecular components that participate) in a chemical reaction that facilitates the generation of data about some entity distinct from the bearer, or the generation of some specified material output distinct from the bearer."@en ;
  rdfs:subClassOf obo:BFO_0000023 .

obo:OBIB_0000427 a rdfs:Class ;
  rdfs:label "ink used for marking surgical margin" ;
  rdfs:comment "A processed material that is used to mark the margin of a surgical excision of a resected tissue. It is used to evaluate whether the margin is free of tumor tissue." ;
  rdfs:subClassOf obo:OBI_0000047 .

obo:OBI_0002152 a rdfs:Class ;
  rdfs:label "EBV IgG antibody assay" ;
  rdfs:comment "An antigen specific antibodies assay that is meant to detect immunoglobulin G (IgG) antibodies that bind to Epstein-Barr virus (EBV) antigens." ;
  rdfs:subClassOf obo:OBI_0002145 .

obo:OBIB_0000467 a rdfs:Class ;
  rdfs:label "research authorization for post mortem specimen donation not obtained because legally authorized representative needed more time to make a decision" ;
  rdfs:comment "A research authorization documentation for post mortem specimen donation in which authorization was not obtained because the the legally authorized representative needed more time to make a decision." ;
  rdfs:subClassOf obo:OBIB_0000459 .

obo:PATO_0000119 a rdfs:Class ;
  rdfs:label "height" ;
  rdfs:comment "A 1-D extent quality inhering in a bearer by virtue of the bearer's vertical dimension of extension." ;
  rdfs:subClassOf obo:PATO_0001708 .

obo:OBI_0002651 a rdfs:Class ;
  rdfs:label "image guided biopsy" ;
  rdfs:comment "A biopsy which uses an imaging procedure to guide a needle biopsy." ;
  rdfs:subClassOf obo:OBI_0002654 .

obo:NCIT_C126534 a rdfs:Class ;
  rdfs:label "Central Asian" ;
  rdfs:comment "Denotes a person whose ancestry is in any of the Asian countries between the Caspian Sea in the west, China in the east, Afghanistan in the south, and Russia in the north." ;
  rdfs:subClassOf obo:OBI_0000181 .

obo:BFO_0000062 a rdf:Property ;
  rdfs:label "preceded by"@en ;
  rdfs:comment "x is preceded by y if and only if the time point at which y ends is before or equivalent to the time point at which x starts. Formally: x preceded by y iff ω(y) <= α(x), where α is a function that maps a process to a start point, and ω is a function that maps a process to an end point."@en ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002222 .

obo:BFO_0000063 a rdf:Property ;
  rdfs:label "precedes"@en ;
  rdfs:comment "x precedes y if and only if the time point at which x ends is before or equivalent to the time point at which y starts. Formally: x precedes y iff ω(x) <= α(y), where α is a function that maps a process to a start point, and ω is a function that maps a process to an end point."@en ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002222 .

obo:BFO_0000067 a rdf:Property ;
  rdfs:label "contains process"@en ;
  rdfs:comment "[copied from inverse property 'occurs in'] b occurs_in c =def b is a process and c is a material entity or immaterial entity& there exists a spatiotemporal region r and b occupies_spatiotemporal_region r.& forall(t) if b exists_at t then c exists_at t & there exist spatial regions s and s’ where & b spatially_projects_onto s at t& c is occupies_spatial_region s’ at t& s is a proper_continuant_part_of s’ at t"@en ;
  rdfs:range <https://w3id.org/linkml/Any> .

obo:BFO_0000156 a rdf:Property ;
  rdfs:label "has temporal occupant"@en ;
  rdfs:range obo:BFO_0000003 .

obo:BFO_0000179 a rdf:Property ;
  rdfs:label "BFO OWL specification label"@en ;
  rdfs:comment "Relates an entity in the ontology to the name of the variable that is used to represent it in the code that generates the BFO OWL file from the lispy specification."@en ;
  rdfs:range xsd:string .

obo:BFO_0000180 a rdf:Property ;
  rdfs:label "BFO CLIF specification label"@en ;
  rdfs:comment "Relates an entity in the ontology to the term that is used to represent it in the the CLIF specification of BFO2"@en ;
  rdfs:range xsd:string .

obo:IAO_0000004 a rdf:Property ;
  rdfs:label "has measurement value"@en ;
  rdfs:range <https://w3id.org/linkml/Any> .

obo:IAO_0000111 a rdf:Property ;
  rdfs:label "editor preferred term"@en ;
  rdfs:comment "The concise, meaningful, and human-friendly name for a class or property preferred by the ontology developers. (US-English)"@en ;
  rdfs:range xsd:string .

obo:IAO_0000112 a rdf:Property ;
  rdfs:label "example of usage"@en ;
  rdfs:comment "A phrase describing how a term should be used and/or a citation to a work which uses it. May also include other kinds of examples that facilitate immediate understanding, such as widely know prototypes or instances of a class, or cases where a relation is said to hold."@en ;
  rdfs:range xsd:string .

obo:IAO_0000113 a rdf:Property ;
  rdfs:label "in branch"@en ;
  rdfs:comment "An annotation property indicating which module the terms belong to. This is currently experimental and not implemented yet."@en ;
  rdfs:range xsd:string .

obo:IAO_0000114 a rdf:Property ;
  rdfs:label "has curation status"@en ;
  rdfs:range xsd:string .

obo:IAO_0000115 a rdf:Property ;
  rdfs:label "definition"@en ;
  rdfs:comment "The official definition, explaining the meaning of a class or property. Shall be Aristotelian, formalized and normalized. Can be augmented with colloquial definitions."@en ;
  rdfs:range xsd:string .

obo:IAO_0000116 a rdf:Property ;
  rdfs:label "editor note"@en ;
  rdfs:comment "An administrative note intended for its editor. It may not be included in the publication version of the ontology, so it should contain nothing necessary for end users to understand the ontology."@en ;
  rdfs:range xsd:string .

obo:IAO_0000117 a rdf:Property ;
  rdfs:label "term editor"@en ;
  rdfs:comment "Name of editor entering the term in the file. The term editor is a point of contact for information regarding the term. The term editor may be, but is not always, the author of the definition, which may have been worked upon by several people"@en ;
  rdfs:range xsd:string .

obo:IAO_0000118 a rdf:Property ;
  rdfs:label "alternative label"@en ;
  rdfs:comment "A label for a class or property that can be used to refer to the class or property instead of the preferred rdfs:label. Alternative labels should be used to indicate community- or context-specific labels, abbreviations, shorthand forms and the like."@en ;
  rdfs:range xsd:string .

obo:IAO_0000119 a rdf:Property ;
  rdfs:label "definition source"@en ;
  rdfs:comment "Formal citation, e.g. identifier in external database to indicate / attribute source(s) for the definition. Free text indicate / attribute source(s) for the definition. EXAMPLE: Author Name, URI, MeSH Term C04, PUBMED ID, Wiki uri on 31.01.2007"@en ;
  rdfs:range xsd:string .

obo:IAO_0000231 a rdf:Property ;
  rdfs:label "has obsolescence reason"@en ;
  rdfs:comment "Relates an annotation property to an obsolescence reason. The values of obsolescence reasons come from a list of predefined terms, instances of the class obsolescence reason specification."@en ;
  rdfs:range xsd:string .

obo:IAO_0000232 a rdf:Property ;
  rdfs:label "curator note"@en ;
  rdfs:comment "An administrative note of use for a curator but of no use for a user"@en ;
  rdfs:range xsd:string .

obo:IAO_0000233 a rdf:Property ;
  rdfs:label "term tracker item"@en ;
  rdfs:comment "An IRI or similar locator for a request or discussion of an ontology term."@en ;
  rdfs:range xsd:string .

obo:IAO_0000234 a rdf:Property ;
  rdfs:label "ontology term requester"@en ;
  rdfs:comment "The name of the person, project, or organization that motivated inclusion of an ontology term by requesting its addition."@en ;
  rdfs:range xsd:string .

obo:IAO_0000235 a rdf:Property ;
  rdfs:label "denoted by"@en ;
  rdfs:comment "inverse of the relation 'denotes'"@en ;
  rdfs:range <https://w3id.org/linkml/Any> .

obo:IAO_0000411 a rdf:Property ;
  rdfs:label "is denotator type"@en ;
  rdfs:comment "Relates an class defined in an ontology, to the type of it's denotator"@en ;
  rdfs:range xsd:string .

obo:IAO_0000412 a rdf:Property ;
  rdfs:label "imported from"@en ;
  rdfs:comment "For external terms/classes, the ontology from which the term was imported"@en ;
  rdfs:range xsd:string .

obo:IAO_0000417 a rdf:Property ;
  rdfs:label "is quality measured as"@en ;
  rdfs:comment "inverse of the relation of is quality measurement of"@en ;
  rdfs:range <https://w3id.org/linkml/Any> .

obo:IAO_0000424 a rdf:Property ;
  rdfs:label "expand expression to"@en ;
  rdfs:comment "A macro expansion tag applied to an object property (or possibly a data property)  which can be used by a macro-expansion engine to generate more complex expressions from simpler ones"@en ;
  rdfs:range xsd:string .

obo:IAO_0000425 a rdf:Property ;
  rdfs:label "expand assertion to"@en ;
  rdfs:comment "A macro expansion tag applied to an annotation property which can be expanded into a more detailed axiom."@en ;
  rdfs:range xsd:string .

obo:IAO_0000426 a rdf:Property ;
  rdfs:label "first order logic expression"@en ;
  rdfs:range xsd:string .

obo:IAO_0000427 a rdf:Property ;
  rdfs:label "antisymmetric property"@en ;
  rdfs:comment "Use boolean value xsd:true to indicate that the property is an antisymmetric property"@en ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:OMO_0001001 .

obo:IAO_0000581 a rdf:Property ;
  rdfs:label "has time stamp"@en ;
  rdfs:comment "relates a time stamped measurement datum to the time measurement datum that denotes the time when the measurement was taken"@en ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:BFO_0000051 .

obo:IAO_0000583 a rdf:Property ;
  rdfs:label "has measurement datum"@en ;
  rdfs:comment "relates a time stamped measurement datum to the measurement datum that was measured"@en ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:BFO_0000051 .

obo:IAO_0000589 a rdf:Property ;
  rdfs:label "OBO foundry unique label"@en ;
  rdfs:comment "An alternative name for a class or property which is unique across the OBO Foundry."@en ;
  rdfs:range xsd:string .

obo:IAO_0000596 a rdf:Property ;
  rdfs:label "has ID digit count"@en ;
  rdfs:comment "Relates an ontology used to record id policy to the number of digits in the URI. The URI is: the 'has ID prefix\" annotation property value concatenated with an integer in the id range (left padded with \"0\"s to make this many digits)"@en ;
  rdfs:range xsd:string .

obo:IAO_0000597 a rdf:Property ;
  rdfs:label "has ID range allocated to"@en ;
  rdfs:comment "Relates a datatype that encodes a range of integers to the name of the person or organization who can use those ids constructed in that range to define new terms"@en ;
  rdfs:range xsd:string .

obo:IAO_0000598 a rdf:Property ;
  rdfs:label "has ID policy for"@en ;
  rdfs:comment "Relating an ontology used to record id policy to the ontology namespace whose policy it manages"@en ;
  rdfs:range xsd:string .

obo:IAO_0000599 a rdf:Property ;
  rdfs:label "has ID prefix"@en ;
  rdfs:comment "Relates an ontology used to record id policy to a prefix concatenated with an integer in the id range (left padded with \"0\"s to make this many digits) to construct an ID for a term being created."@en ;
  rdfs:range xsd:string .

obo:IAO_0000600 a rdf:Property ;
  rdfs:label "elucidation"@en ;
  rdfs:range xsd:string .

obo:IAO_0000601 a rdf:Property ;
  rdfs:label "has associated axiom(nl)"@en ;
  rdfs:range xsd:string .

obo:IAO_0000602 a rdf:Property ;
  rdfs:label "has associated axiom(fol)"@en ;
  rdfs:range xsd:string .

obo:IAO_0000603 a rdf:Property ;
  rdfs:label "is allocated id range"@en ;
  rdfs:comment "Relates an ontology IRI to an (inclusive) range of IRIs in an OBO name space. The range is give as, e.g. \"IAO_0020000-IAO_0020999\""@en ;
  rdfs:range xsd:string .

obo:IAO_0000700 a rdf:Property ;
  rdfs:label "has ontology root term"@en ;
  rdfs:comment "Ontology annotation property. Relates an ontology to a term that is a designated root term of the ontology. Display tools like OLS can use terms annotated with this property as the starting point for rendering the ontology class hierarchy. There can be more than one root."@en ;
  rdfs:range xsd:string .

obo:IAO_0006011 a rdf:Property ;
  rdfs:label "may be identical to"@en ;
  rdfs:comment "A annotation relationship between two terms in an ontology that may refer to the same (natural) type but where more evidence is required before terms are merged."@en ;
  rdfs:range xsd:string .

obo:IAO_0006012 a rdf:Property ;
  rdfs:label "scheduled for obsoletion on or after"@en ;
  rdfs:comment "Used when the class or object is scheduled for obsoletion/deprecation on or after a particular date."@en ;
  rdfs:range xsd:dateTime .

obo:IAO_0010000 a rdf:Property ;
  rdfs:label "has axiom label"@en ;
  rdfs:range xsd:string .

obo:IAO_0020018 a rdf:Property ;
  rdfs:label "is designated by"@en ;
  rdfs:comment "p1 is designated by p2, if p2 is an information content entity that represents p1 in a linguistic context."@en ;
  rdfs:range <https://w3id.org/linkml/Any> .

obo:IAO_0100001 a rdf:Property ;
  rdfs:label "term replaced by"@en ;
  rdfs:comment "Use on obsolete terms, relating the term to another term that can be used as a substitute"@en ;
  rdfs:range xsd:string .

obo:IDO_0000660 a rdf:Property ;
  rdfs:label "results_in"@en ;
  rdfs:range <https://w3id.org/linkml/Any> .

obo:OBI_0000295 a rdf:Property ;
  rdfs:label "is_specified_input_of"@en ;
  rdfs:comment "A relation between a planned process and a continuant participating in that process that is not created during  the process. The presence of the continuant during the process is explicitly specified in the plan specification which the process realizes the concretization of."@en ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0000056 .

obo:OBI_0000833 a rdf:Property ;
  rdfs:label "objective_achieved_by" ;
  rdfs:comment "This relation obtains between an objective specification and a planned process when the criteria specified in the objective specification are met at the end of the planned process." ;
  rdfs:range <https://w3id.org/linkml/Any> .

obo:OBI_0001637 a rdf:Property ;
  rdfs:label "has disposition to bind" ;
  rdfs:comment "A relationship between two material entitites that each have disposition to form a complex with the other." ;
  rdfs:range <https://w3id.org/linkml/Any> .

obo:OBI_0001847 a rdf:Property ;
  rdfs:label "ISA alternative term"@en ;
  rdfs:comment "An alternative term used by the ISA tools project (http://isa-tools.org)." ;
  rdfs:range xsd:string .

obo:OBI_0001886 a rdf:Property ;
  rdfs:label "NIAID GSCID-BRC alternative term"@en ;
  rdfs:comment "An alternative term used by the National Institute of Allergy and Infectious Diseases (NIAID) Genomic Sequencing Centers for Infectious Diseases (GSCID) and Bioinformatics Resource Centers (BRC)." ;
  rdfs:range xsd:string .

obo:OBI_0001938 a rdf:Property ;
  rdfs:label "has value specification" ;
  rdfs:comment "A relation between an information content entity and a value specification that specifies its value." ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:BFO_0000051 .

obo:OBI_0002135 a rdf:Property ;
  rdfs:label "has specified value"@en ;
  rdfs:comment "A relation between a value specification and a literal." ;
  rdfs:range <https://w3id.org/linkml/Any> .

obo:OBI_9991118 a rdf:Property ;
  rdfs:label "IEDB alternative term" ;
  rdfs:comment "An alternative term used by the IEDB." ;
  rdfs:range xsd:string .

obo:OMIABIS_0000008 a rdf:Property ;
  rdfs:label "obsolete owns" ;
  rdfs:range <https://w3id.org/linkml/Any> .

obo:OMIABIS_0000009 a rdf:Property ;
  rdfs:label "obsolete administrates" ;
  rdfs:range <https://w3id.org/linkml/Any> .

obo:OMIABIS_0000042 a rdf:Property ;
  rdfs:label "obsolete is contact information about" ;
  rdfs:range <https://w3id.org/linkml/Any> .

obo:OMIABIS_0000048 a rdf:Property ;
  rdfs:label "obsolete is owned by" ;
  rdfs:range <https://w3id.org/linkml/Any> .

obo:OMO_0001001 a rdf:Property ;
  rdfs:label "logical characteristic of object property" ;
  rdfs:comment "This is an annotation used on an object property to indicate a logical characterstic beyond what is possible in OWL." ;
  rdfs:range xsd:string .

obo:OMO_0002000 a rdf:Property ;
  rdfs:label "defined by construct" ;
  rdfs:comment "Links an annotation property to a SPARQL CONSTRUCT query which is meant to provide semantics for a shortcut relation." ;
  rdfs:range xsd:string .

obo:RO_0000080 a rdf:Property ;
  rdfs:label "quality of"@en ;
  rdfs:comment "a relation between a quality and an independent continuant (the bearer), in which the quality specifically depends on the bearer for its existence"@en ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0000052 .

obo:RO_0000086 a rdf:Property ;
  rdfs:label "has quality"@en ;
  rdfs:comment "a relation between an independent continuant (the bearer) and a quality, in which the quality specifically depends on the bearer for its existence"@en ;
  rdfs:range obo:BFO_0000019 ;
  rdfs:subPropertyOf obo:RO_0000053 .

obo:RO_0000092 a rdf:Property ;
  rdfs:label "disposition of"@en ;
  rdfs:comment "This relation is modeled after the BFO relation of the same name which was in BFO2, but is used in a more restricted sense - specifically, we model this relation as functional (inherited from characteristic-of). Note that this relation is now removed from BFO2020." ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0000052 .

obo:RO_0001001 a rdf:Property ;
  rdfs:label "derives into"@en ;
  rdfs:comment "a relation between two distinct material entities, the old entity and the new entity, in which the new entity begins to exist when the old entity ceases to exist, and the new entity inherits the significant portion of the matter of the old entity"@en ;
  rdfs:range <https://w3id.org/linkml/Any> .

obo:RO_0001015 a rdf:Property ;
  rdfs:label "location of"@en ;
  rdfs:comment "a relation between two independent continuants, the location and the target, in which the target is entirely within the location"@en ;
  rdfs:range <https://w3id.org/linkml/Any> .

obo:RO_0001900 a rdf:Property ;
  rdfs:label "temporal interpretation" ;
  rdfs:comment "An assertion that holds between an OWL Object Property and a temporal interpretation that elucidates how OWL Class Axioms that use this property are to be interpreted in a temporal context." ;
  rdfs:range xsd:string .

obo:RO_0002000 a rdf:Property ;
  rdfs:label "2D boundary of"@en ;
  rdfs:comment "a relation between a 2D immaterial entity (the boundary) and a material entity, in which the boundary delimits the material entity"@en ;
  rdfs:range <https://w3id.org/linkml/Any> .

obo:RO_0002180 a rdf:Property ;
  rdfs:label "has component"@en ;
  rdfs:comment "w 'has component' p if w 'has part' p and w is such that it can be directly disassembled into into n parts p, p2, p3, ..., pn, where these parts are of similar type." ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:BFO_0000051 .

obo:RO_0002211 a rdf:Property ;
  rdfs:label "regulates"@en ;
  rdfs:comment "p regulates q iff p is causally upstream of q, the execution of p is not constant and varies according to specific conditions, and p influences the rate or magnitude of execution of q due to an effect either on some enabler of q or some enabler of a part of q." ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002411 .

obo:RO_0002222 a rdf:Property ;
  rdfs:label "temporally related to"@en ;
  rdfs:range <https://w3id.org/linkml/Any> .

obo:RO_0002223 a rdf:Property ;
  rdfs:label "starts"@en ;
  rdfs:comment "inverse of starts with" ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002222 .

obo:RO_0002233 a rdf:Property ;
  rdfs:label "has input"@en ;
  rdfs:comment "p has input c iff: p is a process, c is a material entity, c is a participant in p, c is present at the start of p, and the state of c is modified during p." ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0000057 .

obo:RO_0002234 a rdf:Property ;
  rdfs:label "has output"@en ;
  rdfs:comment "p has output c iff c is a participant in p, c is present at the end of p, and c is not present in the same state at the beginning of p." ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0000057 .

obo:RO_0002295 a rdf:Property ;
  rdfs:label "results in developmental progression of"@en ;
  rdfs:comment "p results in the developmental progression of s iff p is a developmental process and s is an anatomical entity and p causes s to undergo a change in state at some point along its natural developmental cycle (this cycle starts with its formation, through the mature structure, and ends with its loss)." ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002324 .

obo:RO_0002297 a rdf:Property ;
  rdfs:label "results in formation of"@en ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002295 , obo:RO_0002234 .

obo:RO_0002305 a rdf:Property ;
  rdfs:label "causally upstream of, negative effect" ;
  rdfs:comment "p is causally upstream of, negative effect q iff p is casually upstream of q, and the execution of p decreases the execution of q." ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0004046 , obo:RO_0002411 .

obo:RO_0002324 a rdf:Property ;
  rdfs:label "developmentally related to"@en ;
  rdfs:comment "A relationship that holds between entities participating in some developmental process (GO:0032502)" ;
  rdfs:range <https://w3id.org/linkml/Any> .

obo:RO_0002350 a rdf:Property ;
  rdfs:label "member of"@en ;
  rdfs:comment "is member of is a mereological relation between a item and a collection." ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:BFO_0000050 .

obo:RO_0002352 a rdf:Property ;
  rdfs:label "input of"@en ;
  rdfs:comment "inverse of has input" ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0000056 .

obo:RO_0002353 a rdf:Property ;
  rdfs:label "output of"@en ;
  rdfs:comment "inverse of has output" ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0000056 .

obo:RO_0002410 a rdf:Property ;
  rdfs:label "causally related to"@en ;
  rdfs:comment "relation that links two events, processes, states, or objects such that one event, process, state, or object (a cause) contributes to the production of another event, process, state, or object (an effect) where the cause is partly or wholly responsible for the effect, and the effect is partly or wholly dependent on the cause." ;
  rdfs:range <https://w3id.org/linkml/Any> .

obo:RO_0002411 a rdf:Property ;
  rdfs:label "causally upstream of"@en ;
  rdfs:comment "p is causally upstream of q iff p is causally related to q, the end of p precedes the end of q, and p is not an occurrent part of q." ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002418 , obo:BFO_0000063 .

obo:RO_0002416 a rdf:Property ;
  rdfs:label "logical macro assertion"@en ;
  rdfs:comment "An assertion that involves at least one OWL object that is intended to be expanded into one or more logical axioms. The logical expansion can yield axioms expressed using any formal logical system, including, but not limited to OWL2-DL." ;
  rdfs:range xsd:string .

obo:RO_0002418 a rdf:Property ;
  rdfs:label "causally upstream of or within" ;
  rdfs:comment "p is 'causally upstream or within' q iff p is causally related to q, and the end of p precedes, or is coincident with, the end of q." ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002501 .

obo:RO_0002421 a rdf:Property ;
  rdfs:label "logical macro assertion on a property"@en ;
  rdfs:comment "A logical macro assertion whose domain is an IRI for a property" ;
  rdfs:range xsd:string .

obo:RO_0002422 a rdf:Property ;
  rdfs:label "logical macro assertion on an object property"@en ;
  rdfs:comment "Used to annotate object properties to describe a logical meta-property or characteristic of the object property." ;
  rdfs:range xsd:string .

obo:RO_0002501 a rdf:Property ;
  rdfs:label "causal relation between processes" ;
  rdfs:comment "p is causally related to q if and only if p or any part of p and q or any part of q are linked by a chain of events where each event pair is one where the execution of p influences the execution of q. p may be upstream, downstream, part of, or a container of q." ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002410 .

obo:RO_0004046 a rdf:Property ;
  rdfs:label "causally upstream of or within, negative effect" ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002418 .

obo:RO_0004096 a rdf:Property ;
  rdfs:label "DEPRECATED inheres in"@en ;
  rdfs:comment "DEPRECATED This relation is similar to but different in important respects to the characteristic-of relation. See comments on that relation for more information." ;
  rdfs:range <https://w3id.org/linkml/Any> .

obo:RO_0004097 a rdf:Property ;
  rdfs:label "DEPRECATED bearer of"@en ;
  rdfs:range <https://w3id.org/linkml/Any> .

obo:OBI_0002270 a rdfs:Class ;
  rdfs:label "pathologic lymph node stage for colon and rectum according to AJCC 7th edition" ;
  rdfs:comment "A categorical value specification that is a pathologic finding about one or more characteristics of colorectal cancer following the rules of the TNM AJCC v7 classification system as they pertain to staging of regional lymph nodes." ;
  rdfs:subClassOf obo:OBI_0001930 .

obo:OBI_0002271 a obo:OBI_0002270 ;
  rdfs:label "pN0 (colon)" ;
  rdfs:comment "A pathologic lymph node stage for colon and rectum according to AJCC 7th edition indicating no regional lymph node metastsis." .

obo:OBI_0002272 a obo:OBI_0002270 ;
  rdfs:label "pN1 (colon)" ;
  rdfs:comment "A pathologic lymph node stage for colon and rectum according to AJCC 7th edition indicating metastasis in 1-3 regional lymph nodes." .

obo:OBI_0002273 a obo:OBI_0002270 ;
  rdfs:label "pN1a (colon)" ;
  rdfs:comment "A pathologic lymph node stage for colon and rectum according to AJCC 7th edition indicating metastasis in 1 regional lymph node." .

obo:OBI_0002274 a obo:OBI_0002270 ;
  rdfs:label "pN1b (colon)" ;
  rdfs:comment "A pathologic lymph node stage for colon and rectum according to AJCC 7th edition indicating metastasis in 2-3 regional lymph nodes." .

obo:OBI_0002275 a obo:OBI_0002270 ;
  rdfs:label "pN1c (colon)" ;
  rdfs:comment "A pathologic lymph node stage for colon and rectum according to AJCC 7th edition indicating tumor deposit(s), i.e., satellites in the subserosa, or in non-peritonealized pericolic or perirectal soft tissue without regional lymph node metastasis." .

obo:OBI_0002276 a obo:OBI_0002270 ;
  rdfs:label "pN2 (colon)" ;
  rdfs:comment "A pathologic lymph node stage for colon and rectum according to AJCC 7th edition indicating metastasis in 4 or more regional lymph nodes." .

obo:OBI_0002277 a obo:OBI_0002270 ;
  rdfs:label "pN2a (colon)" ;
  rdfs:comment "A pathologic lymph node stage for colon and rectum according to AJCC 7th edition indicating metastasis in 4 to 6 regional lymph nodes." .

obo:OBI_0002278 a obo:OBI_0002270 ;
  rdfs:label "pN2b (colon)" ;
  rdfs:comment "A pathologic lymph node stage for colon and rectum according to AJCC 7th edition indicating metastasis in 7 or more regional lymph nodes." .

obo:OBI_0002310 a rdfs:Class ;
  rdfs:label "pathologic distant metastases stage for ovary according to AJCC 7th edition" ;
  rdfs:comment "A categorical value specification that is a  pathologic finding about one or more characteristics of ovarian cancer following the rules of the TNM AJCC v7 classification system as they pertain to distant metastases. TNM pathologic distant metastasis findings are based on clinical findings supplemented by histopathologic examination of one or more tissue specimens acquired during surgery." ;
  rdfs:subClassOf obo:OBI_0001930 .

obo:OBI_0002311 a obo:OBI_0002310 ;
  rdfs:label "cM0 (ovary)" ;
  rdfs:comment "A pathologic distant metastases stage for ovary according to AJCC 7th edition indicating that there is no distant metastasis." .

obo:OBI_0002312 a obo:OBI_0002310 ;
  rdfs:label "cM1 (ovary)" ;
  rdfs:comment "A pathologic distant metastases stage for ovary according to AJCC 7th edition indicating that there is distant metastasis except peritoneal metastasis based on clinical assessment." .

obo:OBI_0002313 a obo:OBI_0002310 ;
  rdfs:label "pM1 (ovary)" ;
  rdfs:comment "A pathologic distant metastases stage for ovary according to AJCC 7th edition indicating that there is distant metastasis except peritoneal metastasis that is histologically confirmed." .

obo:OBI_0002314 a rdfs:Class ;
  rdfs:label "clinical tumor stage group according to AJCC 7th edition" ;
  rdfs:comment "A categorical value specification that is an assessment of the stage of a cancer according to the American Joint Committee on Cancer (AJCC) v7 staging systems." ;
  rdfs:subClassOf obo:OBI_0001930 .

obo:OBI_0002315 a obo:OBI_0002314 ;
  rdfs:label "Occult Carcinoma (AJCC 7th)" ;
  rdfs:comment "A clinical tumor stage group according to AJCC 7th edition indicating a small carcinoma, either asymptomatic or giving rise to metastases without symptoms due to the primary carcinoma." .

obo:OBI_0002316 a obo:OBI_0002314 ;
  rdfs:label "Stage 0 (AJCC 7th)" ;
  rdfs:comment "A clinical tumor stage group according to AJCC 7th edition indicating a carcinoma in situ (or melanoma in situ for melanoma of the skin or germ cell neoplasia in situ for testicular germ cell tumors) and generally is considered to have no metastatic potential." .

obo:OBI_0002317 a obo:OBI_0002314 ;
  rdfs:label "Stage I (AJCC 7th)" ;
  rdfs:comment "A clinical tumor stage group according to AJCC 7th edition indicating cancers that are smaller or less deeply invasive without regional disease or nodes." .

obo:OBI_0002318 a obo:OBI_0002314 ;
  rdfs:label "Stage IIA (AJCC 7th)" ;
  rdfs:comment "A clinical tumor stage group according to AJCC 7th edition indicating cancers with increasing tumor or nodal extent but less than in Stage III and with differing characteristics from IIB and IIC." .

obo:OBI_0002319 a obo:OBI_0002314 ;
  rdfs:label "Stage IIB (AJCC 7th)" ;
  rdfs:comment "A clinical tumor stage group according to AJCC 7th edition indicating cancers with increasing tumor or nodal extent but less than in Stage III and with differing characteristics from IIA and IIC." .

obo:OBI_0002320 a obo:OBI_0002314 ;
  rdfs:label "Stage IIC (AJCC 7th)" ;
  rdfs:comment "A clinical tumor stage group according to AJCC 7th edition indicating cancers with increasing tumor or nodal extent but less than in Stage III and with differing characteristics from IIA and IIB." .

obo:OBI_0002321 a obo:OBI_0002314 ;
  rdfs:label "Stage IIIA (AJCC 7th)" ;
  rdfs:comment "A clinical tumor stage group according to AJCC 7th edition indicating cancers with increasing tumor or nodal extent greater than in Stage II and with differing characteristics from IIIB and IIIC." .

obo:OBI_0002322 a obo:OBI_0002314 ;
  rdfs:label "Stage IIIB (AJCC 7th)" ;
  rdfs:comment "A clinical tumor stage group according to AJCC 7th edition indicating cancers with increasing tumor or nodal extent greater than in Stage II and with differing characteristics from IIIA and IIIC." .

obo:OBI_0002323 a obo:OBI_0002314 ;
  rdfs:label "Stage IIIC (AJCC 7th)" ;
  rdfs:comment "A clinical tumor stage group according to AJCC 7th edition indicating cancers with increasing tumor or nodal extent greater than in Stage II and with differing characteristics from IIIA and IIIB." .

obo:OBI_0002324 a obo:OBI_0002314 ;
  rdfs:label "Stage IVA (AJCC 7th)" ;
  rdfs:comment "A clinical tumor stage group according to AJCC 7th edition indicating cancers in patients who present with distant metastases at diagnosis and with differing characteristics from IVB." .

obo:OBI_0002325 a obo:OBI_0002314 ;
  rdfs:label "Stage IVB (AJCC 7th)" ;
  rdfs:comment "A clinical tumor stage group according to AJCC 7th edition indicating cancers in patients who present with distant metastases at diagnosis and with differing characteristics from IVA." .

obo:OBI_0002298 a rdfs:Class ;
  rdfs:label "pathologic distant metastases stage for lung according to AJCC 7th edition" ;
  rdfs:comment "A categorical value specification that is a pathologic finding about one or more characteristics of lung cancer following the rules of the TNM AJCC v7 classification system as they pertain to distant metastases. TNM pathologic distant metastasis findings are based on clinical findings supplemented by histopathologic examination of one or more tissue specimens acquired during surgery." ;
  rdfs:subClassOf obo:OBI_0001930 .

obo:OBI_0002299 a obo:OBI_0002298 ;
  rdfs:label "cM0 (lung)" ;
  rdfs:comment "A pathologic distant metastases stage for lung according to AJCC 7th edition indicating that there is no distant metastasis." .

obo:OBI_0002300 a obo:OBI_0002298 ;
  rdfs:label "cM1 (lung)" ;
  rdfs:comment "A pathologic distant metastases stage for lung according to AJCC 7th edition indicating that there are distant metastases based on clinical assessment." .

obo:OBI_0002301 a obo:OBI_0002298 ;
  rdfs:label "cM1a (lung)" ;
  rdfs:comment "A pathologic distant metastases stage for lung according to AJCC 7th edition indicating that metastasis is based on clinical assessment and a separate tumor nodule(s) in a contralateral lobe; tumor with pleural nodules OR malignant pleural or pericardial effusion." .

obo:OBI_0002302 a obo:OBI_0002298 ;
  rdfs:label "cM1b (lung)" ;
  rdfs:comment "A pathologic distant metastases stage for lung according to AJCC 7th edition indicating that there is a distant metastases based on clinical assessment." .

obo:OBI_0002303 a obo:OBI_0002298 ;
  rdfs:label "pM1 (lung)" ;
  rdfs:comment "A pathologic distant metastases stage for lung according to AJCC 7th edition indicating that there is a distant metastases that is histologically confirmed." .

obo:OBI_0002304 a obo:OBI_0002298 ;
  rdfs:label "pM1a (lung)" ;
  rdfs:comment "A pathologic distant metastases stage for lung according to AJCC 7th edition indicating that metastasis is histologically confirmed and a separate tumor nodule(s) in a contralateral lobe; tumor with pleural nodules OR malignant pleural or pericardial effusion." .

obo:OBI_0002305 a obo:OBI_0002298 ;
  rdfs:label "pM1b (lung)" ;
  rdfs:comment "A pathologic distant metastases stage for lung according to AJCC 7th edition indicating that there is a distant metastases that is histologically confirmed and associated with distant lymph nodes or carcinomatosis." .

obo:OBI_0002341 a rdfs:Class ;
  rdfs:label "International Federation of Gynecology and Obstetrics ovarian cancer stage value specification" ;
  rdfs:comment "A categorical value specification that is a pathologic finding about one or more characteristics of ovarian cancer following the rules of the FIGO classification system." ;
  rdfs:subClassOf obo:OBI_0001930 .

obo:OBI_0002342 a obo:OBI_0002341 ;
  rdfs:label "Stage 1 (FIGO)" ;
  rdfs:comment "A International Federation of Gynecology and Obstetrics ovarian cancer stage value specification associated with TNM stage values of T1, N0, and M0." .

obo:OBI_0002343 a obo:OBI_0002341 ;
  rdfs:label "Stage 1A (FIGO)" ;
  rdfs:comment "A International Federation of Gynecology and Obstetrics ovarian cancer stage value specification associated with TNM stage values of T1a, N0, and M0." .

obo:OBI_0002344 a obo:OBI_0002341 ;
  rdfs:label "Stage 1B (FIGO)" ;
  rdfs:comment "A International Federation of Gynecology and Obstetrics ovarian cancer stage value specification associated with TNM stage values of T1b, N0, and M0." .

obo:OBI_0002345 a obo:OBI_0002341 ;
  rdfs:label "Stage 1C (FIGO)" ;
  rdfs:comment "A International Federation of Gynecology and Obstetrics ovarian cancer stage value specification associated with TNM stage values of T1c, N0, and M0." .

obo:OBI_0002346 a obo:OBI_0002341 ;
  rdfs:label "Stage 2 (FIGO)" ;
  rdfs:comment "A International Federation of Gynecology and Obstetrics ovarian cancer stage value specification associated with TNM stage values of T2, N0, and M0." .

obo:OBI_0002347 a obo:OBI_0002341 ;
  rdfs:label "Stage 2A (FIGO)" ;
  rdfs:comment "A International Federation of Gynecology and Obstetrics ovarian cancer stage value specification associated with TNM stage values of T2a, N0, and M0." .

obo:OBI_0002348 a obo:OBI_0002341 ;
  rdfs:label "Stage 2B (FIGO)" ;
  rdfs:comment "A International Federation of Gynecology and Obstetrics ovarian cancer stage value specification associated with TNM stage values of T2b, N0, and M0." .

obo:OBI_0002349 a obo:OBI_0002341 ;
  rdfs:label "Stage 2C (FIGO)" ;
  rdfs:comment "A International Federation of Gynecology and Obstetrics ovarian cancer stage value specification associated with TNM stage values of T2c, N0, and M0." .

obo:OBI_0002350 a obo:OBI_0002341 ;
  rdfs:label "Stage 3 (FIGO)" ;
  rdfs:comment "A International Federation of Gynecology and Obstetrics ovarian cancer stage value specification associated with TNM stage values of (T3, N0, and M0) or (T3,3a,3b, NX, and M0)." .

obo:OBI_0002351 a obo:OBI_0002341 ;
  rdfs:label "Stage 3A (FIGO)" ;
  rdfs:comment "A International Federation of Gynecology and Obstetrics ovarian cancer stage value specification associated with TNM stage values of T3a, N0, and M0 ." .

obo:OBI_0002352 a obo:OBI_0002341 ;
  rdfs:label "Stage 3B (FIGO)" ;
  rdfs:comment "A International Federation of Gynecology and Obstetrics ovarian cancer stage value specification associated with TNM stage values of T3b, N0, and M0 ." .

obo:OBI_0002353 a obo:OBI_0002341 ;
  rdfs:label "Stage 3C (FIGO)" ;
  rdfs:comment "A International Federation of Gynecology and Obstetrics ovarian cancer stage value specification associated with TNM stage values of (T3c, N0,X and M0) or (any T, N1 and M0)." .

obo:OBI_0002354 a obo:OBI_0002341 ;
  rdfs:label "Stage 4 (FIGO)" ;
  rdfs:comment "A International Federation of Gynecology and Obstetrics ovarian cancer stage value specification associated with TNM stage values of any T, any N, and M1." .

obo:OBI_0002355 a obo:OBI_0002341 ;
  rdfs:label "Stage Unknown (FIGO)" ;
  rdfs:comment "A International Federation of Gynecology and Obstetrics ovarian cancer stage value specification associated with TNM stage values of (T0, N0, and M0) or (T1,1a-1c,2,2a-2c, NX, and M0) or (TX, N0,X, M0)." .

obo:OBI_0002287 a rdfs:Class ;
  rdfs:label "pathologic lymph node stage for ovary according to AJCC 7th edition" ;
  rdfs:comment "A categorical value specification that is a pathologic finding about one or more characteristics of ovarian cancer following the rules of the TNM AJCC v7 classification system as they pertain to staging of regional lymph nodes." ;
  rdfs:subClassOf obo:OBI_0001930 .

obo:OBI_0002288 a obo:OBI_0002287 ;
  rdfs:label "pN0 (ovary)" ;
  rdfs:comment "A pathologic lymph node stage for ovary according to AJCC 7th edition indicating that there is no regional lymph node metastasis." .

obo:OBI_0002289 a obo:OBI_0002287 ;
  rdfs:label "pN1 (ovary)" ;
  rdfs:comment "A pathologic lymph node stage for ovary according to AJCC 7th edition indicating that there is regional lymph node metastasis." .

obo:OBI_0002224 a rdfs:Class ;
  rdfs:label "pathologic primary tumor stage for colon and rectum according to AJCC 7th edition" ;
  rdfs:comment "A categorical value specification that is a pathologic finding about one or more characteristics of colorectal cancer following the rules of the TNM American Joint Committee on Cancer (AJCC) version 7 classification system as they pertain to staging of the primary tumor. TNM pathologic primary tumor findings are based on clinical findings supplemented by histopathologic examination of one or more tissue specimens acquired during surgery." ;
  rdfs:subClassOf obo:OBI_0001930 .

obo:OBI_0002225 a obo:OBI_0002224 ;
  rdfs:label "pT0 (colon)" ;
  rdfs:comment "A pathologic primary tumor stage for colon and rectum according to AJCC 7th edition indicating that there is no evidence of primary tumor." .

obo:OBI_0002226 a obo:OBI_0002224 ;
  rdfs:label "pTis (colon)" ;
  rdfs:comment "A pathologic primary tumor stage for colon and rectum according to AJCC 7th edition indicating carcinoma in situ (intraepithelial or invasion of lamina propria)." .

obo:OBI_0002227 a obo:OBI_0002224 ;
  rdfs:label "pT1 (colon)" ;
  rdfs:comment "A pathologic primary tumor stage for colon and rectum according to AJCC 7th edition indicating that the tumor invades submucosa." .

obo:OBI_0002228 a obo:OBI_0002224 ;
  rdfs:label "pT2 (colon)" ;
  rdfs:comment "A pathologic primary tumor stage for colon and rectum according to AJCC 7th edition indicating that the tumor invades muscularis propria." .

obo:OBI_0002229 a obo:OBI_0002224 ;
  rdfs:label "pT3 (colon)" ;
  rdfs:comment "A pathologic primary tumor stage for colon and rectum according to AJCC 7th edition indicating that the tumor invades subserosa or into non-peritionealized pericolic or perirectal tissues." .

obo:OBI_0002230 a obo:OBI_0002224 ;
  rdfs:label "pT4a (colon)" ;
  rdfs:comment "A pathologic primary tumor stage for colon and rectum according to AJCC 7th edition indicating that the tumor perforates visceral peritoneum." .

obo:OBI_0002231 a obo:OBI_0002224 ;
  rdfs:label "pT4b (colon)" ;
  rdfs:comment "A pathologic primary tumor stage for colon and rectum according to AJCC 7th edition indicating that the tumor directly invades other organs or structures." .

obo:OBI_0002357 a rdfs:Class ;
  rdfs:label "Eastern Cooperative Oncology Group score value specification" ;
  rdfs:comment "A performance status value specification designed by the Eastern Cooperative Oncology Group to assess disease progression and its affect on the daily living abilities of the patient." ;
  rdfs:subClassOf obo:OBI_0002356 .

obo:OBI_0002358 a obo:OBI_0002357 ;
  rdfs:label "3: symptomatic in bed more than 50% of the day but not bed ridden" ;
  rdfs:comment "An Eastern Cooperative Oncology Group score value specification indicating a patient is symptomatic and in bed for more than 50% of the day but is not bed ridden." .

obo:OBI_0002359 a obo:OBI_0002357 ;
  rdfs:label "2: symptomatic but in bed less than 50% of the day" ;
  rdfs:comment "An Eastern Cooperative Oncology Group score value specification indicating a patient is symptomatic but is in bed for less than 50% of the day." .

obo:OBI_0002360 a obo:OBI_0002357 ;
  rdfs:label "4: bed ridden" ;
  rdfs:comment "An Eastern Cooperative Oncology Group score value specification indicating a patient is symptomatic and is bed ridden." .

obo:OBI_0002361 a obo:OBI_0002357 ;
  rdfs:label "0: asymptomatic" ;
  rdfs:comment "An Eastern Cooperative Oncology Group score value specification indicating a patient is asymptomatic." .

obo:OBI_0002362 a obo:OBI_0002357 ;
  rdfs:label "1: symptomatic but fully ambulatory" ;
  rdfs:comment "An Eastern Cooperative Oncology Group score value specification indicating a patient is symptomatic but is fully ambulatory." .

obo:OBI_0002290 a rdfs:Class ;
  rdfs:label "pathologic distant metastases stage for colon according to AJCC 7th edition" ;
  rdfs:comment "A categorical value specification that is a pathologic finding about one or more characteristics of colon cancer following the rules of the TNM AJCC v7 classification system as they pertain to distant metastases. TNM pathologic distant metastasis findings are based on clinical findings supplemented by histopathologic examination of one or more tissue specimens acquired during surgery." ;
  rdfs:subClassOf obo:OBI_0001930 .

obo:OBI_0002291 a obo:OBI_0002290 ;
  rdfs:label "cM0 (colon)" ;
  rdfs:comment "A pathologic distant metastases stage for colon according to AJCC 7th edition indicating that there are no symptoms or signs of distant metastasis." .

obo:OBI_0002292 a obo:OBI_0002290 ;
  rdfs:label "cM1 (colon)" ;
  rdfs:comment "A pathologic distant metastases stage for colon according to AJCC 7th edition indicating that there is clinical evidence of distant metastases by history, physical examination, imaging studies, or invasive procedures, but without microscopic evidence of the presumed distant metastases." .

obo:OBI_0002293 a obo:OBI_0002290 ;
  rdfs:label "cM1a (colon)" ;
  rdfs:comment "A pathologic distant metastases stage for colon according to AJCC 7th edition indicating that metastasis is confined to one organ based on clinical assessment." .

obo:OBI_0002294 a obo:OBI_0002290 ;
  rdfs:label "cM1b (colon)" ;
  rdfs:comment "A pathologic distant metastases stage for colon according to AJCC 7th edition indicating that metastasis is in more than one organ or the peritoneum based on clinical assessment." .

obo:OBI_0002295 a obo:OBI_0002290 ;
  rdfs:label "pM1 (colon)" ;
  rdfs:comment "A pathologic distant metastases stage for colon according to AJCC 7th edition indicating that there is microscopic evidence confirming distant metastatic disease." .

obo:OBI_0002296 a obo:OBI_0002290 ;
  rdfs:label "pM1a (colon)" ;
  rdfs:comment "A pathologic distant metastases stage for colon according to AJCC 7th edition indicating that metastasis is confined to one organ and histologically confirmed." .

obo:OBI_0002297 a obo:OBI_0002290 ;
  rdfs:label "pM1b (colon)" ;
  rdfs:comment "A pathologic distant metastases stage for colon according to AJCC 7th edition indicating that metastasis is in more than one organ or the peritoneum and histologically confirmed." .

obo:UO_0000005 a rdfs:Class ;
  rdfs:label "temperature unit" ;
  rdfs:subClassOf obo:IAO_0000003 .

obo:UO_0000027 a obo:UO_0000005 ;
  rdfs:label "degree Celsius" .

obo:UO_0000195 a obo:UO_0000005 ;
  rdfs:label "degree Fahrenheit" .

obo:OBI_0002279 a rdfs:Class ;
  rdfs:label "pathologic lymph node stage for lung according to AJCC 7th edition" ;
  rdfs:comment "A categorical value specification that is a pathologic finding about one or more characteristics of lung cancer following the rules of the TNM AJCC v7 classification system as they pertain to staging of regional lymph nodes." ;
  rdfs:subClassOf obo:OBI_0001930 .

obo:OBI_0002280 a obo:OBI_0002279 ;
  rdfs:label "pN0 (lung)" ;
  rdfs:comment "A pathologic lymph node stage for lung according to AJCC 7th edition indicating no regional lymph node metastasis." .

obo:OBI_0002281 a obo:OBI_0002279 ;
  rdfs:label "pN1 (lung)" ;
  rdfs:comment "A pathologic lymph node stage for lung according to AJCC 7th edition indicating metastasis in ipsilateral peribronchial and/or ipsilateral hilar lymph nodes and intrapulmonary nodes, including involvement by direct extension." .

obo:OBI_0002282 a obo:OBI_0002279 ;
  rdfs:label "pN2 (lung)" ;
  rdfs:comment "A pathologic lymph node stage for lung according to AJCC 7th edition indicating metastasis in ipsilateral mediastinal and/or subcarinal lymph node(s)." .

obo:OBI_0002283 a obo:OBI_0002279 ;
  rdfs:label "pN3 (lung)" ;
  rdfs:comment "A pathologic lymph node stage for lung according to AJCC 7th edition indicating metastasis in contralateral mediastinal, contralateral hilar, ipsilateral or contralateral scalene, or supraclavicular lymph node(s)." .

obo:OBI_0002219 a rdfs:Class ;
  rdfs:label "histologic grade for ovarian tumor according to the World Health Organization" ;
  rdfs:comment "A histologic grade for ovarian tumor that is from a histological classification by the World Health Organization (WHO)." ;
  rdfs:subClassOf obo:OBI_0002215 .

obo:OBI_0002220 a obo:OBI_0002219 ;
  rdfs:label "G1 (WHO)" ;
  rdfs:comment "A histologic grade for ovarian tumor according to the World Health Organization indicating that the tumor is well differentiated." .

obo:OBI_0002221 a obo:OBI_0002219 ;
  rdfs:label "G2 (WHO)" ;
  rdfs:comment "A histologic grade for ovarian tumor according to the World Health Organization indicating that the tumor is moderately differentiated." .

obo:OBI_0002222 a obo:OBI_0002219 ;
  rdfs:label "G3 (WHO)" ;
  rdfs:comment "A histologic grade for ovarian tumor according to the World Health Organization indicating that the tumor is poorly differentiated." .

obo:OBI_0002223 a obo:OBI_0002219 ;
  rdfs:label "G4 (WHO)" ;
  rdfs:comment "A histologic grade for ovarian tumor according to the World Health Organization indicating that the tumor is undifferentiated." .

obo:OBI_0002306 a rdfs:Class ;
  rdfs:label "pathologic distant metastases stage for kidney according to AJCC 7th edition" ;
  rdfs:comment "A categorical value specification that is a pathologic finding about one or more characteristics of renal cancer following the rules of the TNM AJCC v7 classification system as they pertain to distant metastases. TNM pathologic distant metastasis findings are based on clinical findings supplemented by histopathologic examination of one or more tissue specimens acquired during surgery." ;
  rdfs:subClassOf obo:OBI_0001930 .

obo:OBI_0002307 a obo:OBI_0002306 ;
  rdfs:label "cM0 (kidney)" ;
  rdfs:comment "A pathologic distant metastases stage for kidney according to AJCC 7th edition indicating that there is no distant metastasis." .

obo:OBI_0002308 a obo:OBI_0002306 ;
  rdfs:label "cM1 (kidney)" ;
  rdfs:comment "A pathologic distant metastases stage for kidney according to AJCC 7th edition indicating that there are distant metastases based on clinical assessment." .

obo:OBI_0002309 a obo:OBI_0002306 ;
  rdfs:label "pM1 (kidney)" ;
  rdfs:comment "A pathologic distant metastases stage for kidney according to AJCC 7th edition indicating that there is a distant metastases that is histologically confirmed." .

obo:OBI_0002210 a rdfs:Class ;
  rdfs:label "histologic grade according to the Fuhrman Nuclear Grading System" ;
  rdfs:comment "A categorical value specification that is a histologic grade assigned to a tumor slide specimen according to the Fuhrman Nuclear Grading System." ;
  rdfs:subClassOf obo:OBI_0001930 .

obo:OBI_0002211 a obo:OBI_0002210 ;
  rdfs:label "G1 (Fuhrman)" ;
  rdfs:comment "A histologic grade according to the Fuhrman Nuclear Grading System indicating that nuclei are round, uniform, approximately 10um and that nucleoli are inconspicuous or absent." .

obo:OBI_0002212 a obo:OBI_0002210 ;
  rdfs:label "G2 (Fuhrman)" ;
  rdfs:comment "A histologic grade according to the Fuhrman Nuclear Grading System indicating that nuclei are slightly irregular, approximately 15um and nucleoli are evident." .

obo:OBI_0002213 a obo:OBI_0002210 ;
  rdfs:label "G3 (Fuhrman)" ;
  rdfs:comment "A histologic grade according to the Fuhrman Nuclear Grading System indicating that nuclei are very irregular, approximately 20um and nucleoli large and prominent." .

obo:OBI_0002214 a obo:OBI_0002210 ;
  rdfs:label "G4 (Fuhrman)" ;
  rdfs:comment "A histologic grade according to the Fuhrman Nuclear Grading System indicating that nuclei arei bizarre and multilobulated, 20um or greater and nucleoli are prominent and chromatin clumped." .

obo:OBI_0002243 a rdfs:Class ;
  rdfs:label "pathologic primary tumor stage for kidney according to AJCC 7th edition" ;
  rdfs:comment "A categorical value specification that is a pathologic finding about one or more characteristics of renal cancer following the rules of the TNM AJCC v7 classification system as they pertain to staging of the primary tumor. TNM pathologic primary tumor findings are based on clinical findings supplemented by histopathologic examination of one or more tissue specimens acquired during surgery." ;
  rdfs:subClassOf obo:OBI_0001930 .

obo:OBI_0002244 a obo:OBI_0002243 ;
  rdfs:label "pT0 (kidney)" ;
  rdfs:comment "A pathologic primary tumor stage for kidney according to AJCC 7th edition indicating that there is no evidence of primary tumor." .

obo:OBI_0002245 a obo:OBI_0002243 ;
  rdfs:label "pT1 (kidney)" ;
  rdfs:comment "A pathologic primary tumor stage for kidney according to AJCC 7th edition indicating that the tumor is 7 cm or less in greatest dimension and limited to the kidney." .

obo:OBI_0002246 a obo:OBI_0002243 ;
  rdfs:label "pT1a (kidney)" ;
  rdfs:comment "A pathologic primary tumor stage for kidney according to AJCC 7th edition indicating that the tumor is 4 cm or less." .

obo:OBI_0002247 a obo:OBI_0002243 ;
  rdfs:label "pT1b (kidney)" ;
  rdfs:comment "A pathologic primary tumor stage for kidney according to AJCC 7th edition indicating that the tumor is more than 4 cm but not more than 7 cm." .

obo:OBI_0002248 a obo:OBI_0002243 ;
  rdfs:label "pT2 (kidney)" ;
  rdfs:comment "A pathologic primary tumor stage for kidney according to AJCC 7th edition indicating that the tumor is more than 7 cm in greatest dimension and limited to the kidney." .

obo:OBI_0002249 a obo:OBI_0002243 ;
  rdfs:label "pT2a (kidney)" ;
  rdfs:comment "A pathologic primary tumor stage for kidney according to AJCC 7th edition indicating that the tumor is more than 7 cm but not more than 10 cm." .

obo:OBI_0002250 a obo:OBI_0002243 ;
  rdfs:label "pT2b (kidney)" ;
  rdfs:comment "A pathologic primary tumor stage for kidney according to AJCC 7th edition indicating that the tumor is more than 10 cm and limited to the kidney." .

obo:OBI_0002251 a obo:OBI_0002243 ;
  rdfs:label "pT3 (kidney)" ;
  rdfs:comment "A pathologic primary tumor stage for kidney according to AJCC 7th edition indicating that the tumor extends into major veins or perinephric tissues but not into the ipsilateral adrenal gland and not beyond the Gerota fascia." .

obo:OBI_0002252 a obo:OBI_0002243 ;
  rdfs:label "pT3a (kidney)" ;
  rdfs:comment "A pathologic primary tumor stage for kidney according to AJCC 7th edition indicating that the tumor grossly extends into the renal vein or its segmental (muscle containing) branches, or the tumor invades perirenal and/or renal sinus fat (peripelvic) fat but not beyond Gerota fascia." .

obo:OBI_0002253 a obo:OBI_0002243 ;
  rdfs:label "pT3b (kidney)" ;
  rdfs:comment "A pathologic primary tumor stage for kidney according to AJCC 7th edition indicating that the tumor grossly extends into vena cava below diaphragm." .

obo:OBI_0002254 a obo:OBI_0002243 ;
  rdfs:label "pT3c (kidney)" ;
  rdfs:comment "A pathologic primary tumor stage for kidney according to AJCC 7th edition indicating that the tumor grossly extends into vena cava above the diaphragm or Invades the wall of the vena cava." .

obo:OBI_0002255 a obo:OBI_0002243 ;
  rdfs:label "pT4 (kidney)" ;
  rdfs:comment "A pathologic primary tumor stage for kidney according to AJCC 7th edition indicating that the tumor invades beyond Gerota fascia (including contiguous extension into the ipsilateral adrenal gland)." .

obo:IAO_0000225 a rdfs:Class ;
  rdfs:label "obsolescence reason specification"@en ;
  rdfs:comment "The reason for which a term has been deprecated. The allowed values come from an enumerated list of predefined terms. See the specification of these instances for more detailed definitions of each enumerated value."@en ;
  rdfs:subClassOf obo:IAO_0000102 .

obo:IAO_0000103 a obo:IAO_0000225 ;
  rdfs:label "failed exploratory term"@en ;
  rdfs:comment "The term was used in an attempt to structure part of the ontology but in retrospect failed to do a good job"@en .

obo:IAO_0000226 a obo:IAO_0000225 ;
  rdfs:label "placeholder removed"@en .

obo:IAO_0000227 a obo:IAO_0000225 ;
  rdfs:label "terms merged"@en .

obo:IAO_0000228 a obo:IAO_0000225 ;
  rdfs:label "term imported"@en .

obo:IAO_0000229 a obo:IAO_0000225 ;
  rdfs:label "term split"@en .

obo:OMO_0001000 a obo:IAO_0000225 ;
  rdfs:label "out of scope" ;
  rdfs:comment "The term was added to the ontology on the assumption it was in scope, but it turned out later that it was not."@en .

obo:IAO_0000409 a rdfs:Class ;
  rdfs:label "denotator type"@en ;
  rdfs:comment "A denotator type indicates how a term should be interpreted from an ontological perspective."@en ;
  rdfs:subClassOf obo:IAO_0000102 .

obo:IAO_0000410 a obo:IAO_0000409 ;
  rdfs:label "universal"@en .

obo:IAO_0000420 a obo:IAO_0000409 ;
  rdfs:label "defined class"@en ;
  rdfs:comment "A defined class is a class that is defined by a set of logically necessary and sufficient conditions but is not a universal"@en .

obo:IAO_0000421 a obo:IAO_0000409 ;
  rdfs:label "named class expression"@en ;
  rdfs:comment "A named class expression is a logical expression that is given a name. The name can be used in place of the expression."@en .

obo:OBI_0002216 a rdfs:Class ;
  rdfs:label "histologic grade for ovarian tumor according to a two-tier grading system" ;
  rdfs:comment "A histologic grade for ovarian tumor that is from a two-tier histological classification of tumors." ;
  rdfs:subClassOf obo:OBI_0002215 .

obo:OBI_0002217 a obo:OBI_0002216 ;
  rdfs:label "Low grade ovarian tumor" ;
  rdfs:comment "A histologic grade for ovarian tumor according to a two-tier grading system indicating that the tumor is low grade." .

obo:OBI_0002218 a obo:OBI_0002216 ;
  rdfs:label "High grade ovarian tumor" ;
  rdfs:comment "A histologic grade for ovarian tumor according to a two-tier grading system indicating that the tumor is high grade." .

obo:OBI_0002205 a rdfs:Class ;
  rdfs:label "histologic grade according to AJCC 7th edition" ;
  rdfs:comment "A categorical value specification that is a histologic grade assigned to a tumor slide specimen according to the American Joint Committee on Cancer (AJCC) 7th Edition grading system." ;
  rdfs:subClassOf obo:OBI_0001930 .

obo:OBI_0002206 a obo:OBI_0002205 ;
  rdfs:label "G1: Well differentiated" ;
  rdfs:comment "A histologic grade according to AJCC 7th edition indicating that the tumor cells and the organization of the tumor tissue appear close to normal." .

obo:OBI_0002207 a obo:OBI_0002205 ;
  rdfs:label "G2: Moderately differentiated" ;
  rdfs:comment "A histologic grade according to AJCC 7th edition indicating that the tumor cells are moderately differentiated and reflect an intermediate grade." .

obo:OBI_0002208 a obo:OBI_0002205 ;
  rdfs:label "G3: Poorly differentiated" ;
  rdfs:comment "A histologic grade according to AJCC 7th edition indicating that the tumor cells are poorly differentiated and do not look like normal cells and tissue." .

obo:OBI_0002209 a obo:OBI_0002205 ;
  rdfs:label "G4: Undifferentiated" ;
  rdfs:comment "A histologic grade according to AJCC 7th edition indicating that the tumor cells are undifferentiated and do not look like normal cells and tissue." .

obo:OBIB_0000087 a rdfs:Class ;
  rdfs:label "autolysis value specification" ;
  rdfs:comment "A categorical value specification that is used to record the destruction of an organism cells or tissues by the organisms' own enzymes or processes with nominal categories ranging from none to severe." ;
  rdfs:subClassOf obo:OBI_0001930 .

obo:OBI_0002009 a obo:OBIB_0000087 ;
  rdfs:label "0-non autolyis"@en ;
  rdfs:comment "An autolysis value specification that indicates no apparent autolytic destruction of an organism cells or tissues." .

obo:OBI_0002010 a obo:OBIB_0000087 ;
  rdfs:label "1-slight autolysis"@en ;
  rdfs:comment "An autolysis value specification that indicates slight autolytic destruction of an organism cells or tissues." .

obo:OBI_0002011 a obo:OBIB_0000087 ;
  rdfs:label "2-moderate autolysis"@en ;
  rdfs:comment "An autolysis value specification that indicates moderate autolytic destruction of an organism cells or tissues." .

obo:OBI_0002012 a obo:OBIB_0000087 ;
  rdfs:label "3-severe autolysis"@en ;
  rdfs:comment "An autolysis value specification that indicates severe autolytic destruction of an organism cells or tissues." .

obo:UO_0000003 a rdfs:Class ;
  rdfs:label "time unit" ;
  rdfs:subClassOf obo:IAO_0000003 .

obo:UO_0000010 a obo:UO_0000003 ;
  rdfs:label "second" .

obo:UO_0000031 a obo:UO_0000003 ;
  rdfs:label "minute" .

obo:UO_0000032 a obo:UO_0000003 ;
  rdfs:label "hour" .

obo:UO_0000033 a obo:UO_0000003 ;
  rdfs:label "day" .

obo:UO_0000034 a obo:UO_0000003 ;
  rdfs:label "week" .

obo:UO_0000035 a obo:UO_0000003 ;
  rdfs:label "month" .

obo:UO_0000036 a obo:UO_0000003 ;
  rdfs:label "year" .

obo:OBI_0000639 a rdfs:Class ;
  rdfs:label "material separation objective" ;
  rdfs:comment "is an objective to transform a material entity into spatially separated components." ;
  rdfs:subClassOf obo:OBI_0000456 .

obo:OBI_0000678 a obo:OBI_0000639 ;
  rdfs:label "portioning objective" ;
  rdfs:comment "A material separation objective aiming to separate material into multiple portions, each of which contains a similar composition of the input material." .

obo:OBI_0000681 a obo:OBI_0000639 ;
  rdfs:label "separation into different composition objective" ;
  rdfs:comment "A material separation objective aiming to separate a material entity that has parts of different types, and end with at least one output that is a material with parts of fewer types (modulo impurities)." .

obo:UO_0000051 a rdfs:Class ;
  rdfs:label "concentration unit" ;
  rdfs:subClassOf obo:IAO_0000003 .

obo:UO_0000062 a obo:UO_0000051 ;
  rdfs:label "molar" .

obo:UO_0000063 a obo:UO_0000051 ;
  rdfs:label "millimolar" .

obo:UO_0000064 a obo:UO_0000051 ;
  rdfs:label "micromolar" .

obo:UO_0000065 a obo:UO_0000051 ;
  rdfs:label "nanomolar" .

obo:UO_0000066 a obo:UO_0000051 ;
  rdfs:label "picomolar" .

obo:UO_0000163 a obo:UO_0000051 ;
  rdfs:label "mass percentage" .

obo:UO_0000164 a obo:UO_0000051 ;
  rdfs:label "mass volume percentage" .

obo:UO_0000165 a obo:UO_0000051 ;
  rdfs:label "volume percentage" .

obo:UO_0000175 a obo:UO_0000051 ;
  rdfs:label "gram per liter" .

obo:UO_0000176 a obo:UO_0000051 ;
  rdfs:label "milligram per milliliter" .

obo:UO_0000196 a obo:UO_0000051 ;
  rdfs:label "pH" .

obo:UO_0000207 a obo:UO_0000051 ;
  rdfs:label "milliliter per liter" .

obo:UO_0000208 a obo:UO_0000051 ;
  rdfs:label "gram per deciliter" .

obo:UO_0000212 a obo:UO_0000051 ;
  rdfs:label "colony forming unit per volume" .

obo:UO_0000301 a obo:UO_0000051 ;
  rdfs:label "microgram per liter" .

obo:OBI_0002326 a rdfs:Class ;
  rdfs:label "International Federation of Gynecology and Obstetrics cervical cancer stage value specification" ;
  rdfs:comment "A categorical value specification that is an assessment of the stage of a gynecologic cancer according to the International Federation of Gynecology and Obstetrics (FIGO) staging systems." ;
  rdfs:subClassOf obo:OBI_0001930 .

obo:OBI_0002327 a obo:OBI_0002326 ;
  rdfs:label "Stage IA (FIGO)" ;
  rdfs:comment "An International Federation of Gynecology and Obstetrics cervical cancer stage value specification indicating invasive carcinoma which can be diagnosed only by microscopy, with deepest invasion <5 mm and the largest extension <7 mm." .

obo:OBI_0002328 a obo:OBI_0002326 ;
  rdfs:label "Stage IA1 (FIGO)" ;
  rdfs:comment "An International Federation of Gynecology and Obstetrics cervical cancer stage value specification indicating measured stromal invasion of <3.0 mm in depth and extension of <7.0 mm." .

obo:OBI_0002329 a obo:OBI_0002326 ;
  rdfs:label "Stage IA2 (FIGO)" ;
  rdfs:comment "An International Federation of Gynecology and Obstetrics cervical cancer stage value specification indicating measured stromal invasion of >3.0 mm and not >5.0 mm with an extension of not >7.0 mm." .

obo:OBI_0002330 a obo:OBI_0002326 ;
  rdfs:label "Stage IB (FIGO)" ;
  rdfs:comment "An International Federation of Gynecology and Obstetrics cervical cancer stage value specification indicating clinically visible lesions limited to the cervix uteri or pre-clinical cancers greater than stage IA" .

obo:OBI_0002331 a obo:OBI_0002326 ;
  rdfs:label "Stage IB1 (FIGO)" ;
  rdfs:comment "An International Federation of Gynecology and Obstetrics cervical cancer stage value specification indicating clinically visible lesion limited to the cervix uteri or pre-clinical cancers greater than stage IA <4.0 cm in greatest dimension." .

obo:OBI_0002332 a obo:OBI_0002326 ;
  rdfs:label "Stage IB2 (FIGO)" ;
  rdfs:comment "An International Federation of Gynecology and Obstetrics cervical cancer stage value specification indicating clinically visible lesion limited to the cervix uteri or pre-clinical cancers greater than stage IA >4.0 cm in greatest dimension." .

obo:OBI_0002333 a obo:OBI_0002326 ;
  rdfs:label "Stage IIA (FIGO)" ;
  rdfs:comment "An International Federation of Gynecology and Obstetrics cervical cancer stage value specification indicating cervical carcinoma invades beyond the uterus, but not to the pelvic wall or to the lower third of the vagina without parametrial invasion." .

obo:OBI_0002334 a obo:OBI_0002326 ;
  rdfs:label "Stage IIA1 (FIGO)" ;
  rdfs:comment "An International Federation of Gynecology and Obstetrics cervical cancer stage value specification indicating cervical carcinoma invades beyond the uterus, but not to the pelvic wall or to the lower third of the vagina without parametrial invasion and clinically visible lesion <4.0 cm in greatest dimension." .

obo:OBI_0002335 a obo:OBI_0002326 ;
  rdfs:label "Stage IIA2 (FIGO)" ;
  rdfs:comment "An International Federation of Gynecology and Obstetrics cervical cancer stage value specification indicating cervical carcinoma invades beyond the uterus, but not to the pelvic wall or to the lower third of the vagina without parametrial invasion and clinically visible lesion >4.0 cm in greatest dimension." .

obo:OBI_0002336 a obo:OBI_0002326 ;
  rdfs:label "Stage IIB (FIGO)" ;
  rdfs:comment "An International Federation of Gynecology and Obstetrics cervical cancer stage value specification indicating cervical carcinoma invades beyond the uterus, but not to the pelvic wall or to the lower third of the vagina with obvious parametrial invasion." .

obo:OBI_0002337 a obo:OBI_0002326 ;
  rdfs:label "Stage IIIA (FIGO)" ;
  rdfs:comment "An International Federation of Gynecology and Obstetrics cervical cancer stage value specification indicating tumour involves lower third of the vagina, with no extension to the pelvic wall." .

obo:OBI_0002338 a obo:OBI_0002326 ;
  rdfs:label "Stage IIIB (FIGO)" ;
  rdfs:comment "An International Federation of Gynecology and Obstetrics cervical cancer stage value specification indicating extension to the pelvic wall and/or hydronephrosis or non-functioning kidney." .

obo:OBI_0002339 a obo:OBI_0002326 ;
  rdfs:label "Stage IVA (FIGO)" ;
  rdfs:comment "An International Federation of Gynecology and Obstetrics cervical cancer stage value specification indicating spread of the growth to adjacent organs." .

obo:OBI_0002340 a obo:OBI_0002326 ;
  rdfs:label "Stage IVB (FIGO)" ;
  rdfs:comment "An International Federation of Gynecology and Obstetrics cervical cancer stage value specification indicating spread to distant organs." .

obo:OBI_0002284 a rdfs:Class ;
  rdfs:label "pathologic lymph node stage for kidney according to AJCC 7th edition" ;
  rdfs:comment "A categorical value specification that is a pathologic finding about one or more characteristics of renal cancer following the rules of the TNM AJCC v7 classification system as they pertain to staging of regional lymph nodes." ;
  rdfs:subClassOf obo:OBI_0001930 .

obo:OBI_0002285 a obo:OBI_0002284 ;
  rdfs:label "pN0 (kidney)" ;
  rdfs:comment "A pathologic lymph node stage for kidney according to AJCC 7th edition indicating that there is no regional lymph node metastasis." .

obo:OBI_0002286 a obo:OBI_0002284 ;
  rdfs:label "pN1 (kidney)" ;
  rdfs:comment "A pathologic lymph node stage for kidney according to AJCC 7th edition indicating that there is regional lymph node metastasis." .

obo:OBI_0002363 a rdfs:Class ;
  rdfs:label "Karnofsky score vaue specification" ;
  rdfs:comment "A performance status value specification designed for classifying patients 16 years of age or older by their functional impairment." ;
  rdfs:subClassOf obo:OBI_0002356 .

obo:OBI_0002364 a obo:OBI_0002363 ;
  rdfs:label "100: asymptomatic" ;
  rdfs:comment "A Karnofsky score vaue specification indicating that a patient is asymptomatic." .

obo:OBI_0002365 a obo:OBI_0002363 ;
  rdfs:label "80-90: symptomatic but fully ambulatory" ;
  rdfs:comment "A Karnofsky score vaue specification indicating that a patient is symptomatic but fully ambulatory." .

obo:OBI_0002366 a obo:OBI_0002363 ;
  rdfs:label "60-70: symptomatic but in bed less than 50% of the day" ;
  rdfs:comment "A Karnofsky score vaue specification indicating that a patient is symptomatic but in bed less than 50% of the day." .

obo:OBI_0002367 a obo:OBI_0002363 ;
  rdfs:label "40-50: symptomatic, in bed more than 50% of the day, but not bed ridden" ;
  rdfs:comment "A Karnofsky score vaue specification indicating that a patient is symptomatic, in bed more than 50% of the day, but not bed ridden." .

obo:IAO_0000078 a rdfs:Class ;
  rdfs:label "curation status specification"@en ;
  rdfs:comment "The curation status of the term. The allowed values come from an enumerated list of predefined terms. See the specification of these instances for more detailed definitions of each enumerated value."@en ;
  rdfs:subClassOf obo:IAO_0000102 .

obo:IAO_0000002 a obo:IAO_0000078 ;
  rdfs:label "example to be eventually removed"@en .

obo:IAO_0000120 a obo:IAO_0000078 ;
  rdfs:label "metadata complete"@en ;
  rdfs:comment "Class has all its metadata, but is either not guaranteed to be in its final location in the asserted IS_A hierarchy or refers to another class that is not complete."@en .

obo:IAO_0000121 a obo:IAO_0000078 ;
  rdfs:label "organizational term"@en ;
  rdfs:comment "Term created to ease viewing/sort terms for development purpose, and will not be included in a release"@en .

obo:IAO_0000122 a obo:IAO_0000078 ;
  rdfs:label "ready for release"@en ;
  rdfs:comment "Class has undergone final review, is ready for use, and will be included in the next release. Any class lacking \"ready_for_release\" should be considered likely to change place in hierarchy, have its definition refined, or be obsoleted in the next release.  Those classes deemed \"ready_for_release\" will also derived from a chain of ancestor classes that are also \"ready_for_release.\""@en .

obo:IAO_0000123 a obo:IAO_0000078 ;
  rdfs:label "metadata incomplete"@en ;
  rdfs:comment "Class is being worked on; however, the metadata (including definition) are not complete or sufficiently clear to the branch editors."@en .

obo:IAO_0000124 a obo:IAO_0000078 ;
  rdfs:label "uncurated"@en ;
  rdfs:comment "Nothing done yet beyond assigning a unique class ID and proposing a preferred term."@en .

obo:IAO_0000125 a obo:IAO_0000078 ;
  rdfs:label "pending final vetting"@en ;
  rdfs:comment "All definitions, placement in the asserted IS_A hierarchy and required minimal metadata are complete. The class is awaiting a final review by someone other than the term editor."@en .

obo:IAO_0000423 a obo:IAO_0000078 ;
  rdfs:label "to be replaced with external ontology term"@en ;
  rdfs:comment "Terms with this status should eventually replaced with a term from another ontology."@en .

obo:IAO_0000428 a obo:IAO_0000078 ;
  rdfs:label "requires discussion"@en ;
  rdfs:comment "A term that is metadata complete, has been reviewed, and problems have been identified that require discussion before release. Such a term requires editor note(s) to identify the outstanding issues."@en .

obo:OBI_0002256 a rdfs:Class ;
  rdfs:label "pathologic primary tumor stage for ovary according to AJCC 7th edition" ;
  rdfs:comment "A categorical value specification that is a pathologic finding about one or more characteristics of ovarian cancer following the rules of the TNM AJCC v7 classification system as they pertain to staging of the primary tumor. TNM pathologic primary tumor findings are based on clinical findings supplemented by histopathologic examination of one or more tissue specimens acquired during surgery." ;
  rdfs:subClassOf obo:OBI_0001930 .

obo:OBI_0002257 a obo:OBI_0002256 ;
  rdfs:label "pT0 (ovary)" ;
  rdfs:comment "A pathologic primary tumor stage for ovary according to AJCC 7th edition indicating that there is no evidence of primary tumor." .

obo:OBI_0002258 a obo:OBI_0002256 ;
  rdfs:label "pT1 (ovary)" ;
  rdfs:comment "A pathologic primary tumor stage for ovary according to AJCC 7th edition indicating that the tumor is limited to the ovaries (one or both)." .

obo:OBI_0002259 a obo:OBI_0002256 ;
  rdfs:label "pT1a (ovary)" ;
  rdfs:comment "A pathologic primary tumor stage for ovary according to AJCC 7th edition indicating that the tumor is limited to one ovary; capsule intact, no tumor on ovarian surface and no malignant cells in ascites or peritoneal washings." .

obo:OBI_0002260 a obo:OBI_0002256 ;
  rdfs:label "pT1b (ovary)" ;
  rdfs:comment "A pathologic primary tumor stage for ovary according to AJCC 7th edition indicating that the tumor is limited to both ovaries; capsule intact, no tumor on ovarian surface and no malignant cells in ascites or peritoneal washings." .

obo:OBI_0002261 a obo:OBI_0002256 ;
  rdfs:label "pT1c (ovary)" ;
  rdfs:comment "A pathologic primary tumor stage for ovary according to AJCC 7th edition indicating that the tumor is limited to one or both ovaries with capsule ruptured, tumor on ovarian surface, or malignant cells in ascites or peritoneal washings." .

obo:OBI_0002262 a obo:OBI_0002256 ;
  rdfs:label "pT2 (ovary)" ;
  rdfs:comment "A pathologic primary tumor stage for ovary according to AJCC 7th edition indicating that the tumor involves one or both ovaries with pelvic extension." .

obo:OBI_0002263 a obo:OBI_0002256 ;
  rdfs:label "pT2a (ovary)" ;
  rdfs:comment "A pathologic primary tumor stage for ovary according to AJCC 7th edition indicating that the tumor has extension and/or implants on uterus and/or tube(s) and no malignant cells in ascites or peritoneal washings." .

obo:OBI_0002264 a obo:OBI_0002256 ;
  rdfs:label "pT2b (ovary)" ;
  rdfs:comment "A pathologic primary tumor stage for ovary according to AJCC 7th edition indicating that the tumor has extension to other pelvic tissues and no malignant cells in ascites or peritoneal washings." .

obo:OBI_0002265 a obo:OBI_0002256 ;
  rdfs:label "pT2c (ovary)" ;
  rdfs:comment "A pathologic primary tumor stage for ovary according to AJCC 7th edition indicating that the tumor has pelvic extension with malignant cells in ascites or peritoneal washings." .

obo:OBI_0002266 a obo:OBI_0002256 ;
  rdfs:label "pT3 (ovary)" ;
  rdfs:comment "A pathologic primary tumor stage for ovary according to AJCC 7th edition indicating that the tumor involves one or both ovaries with microscopically confirmed peritoneal metastasis outside the pelvis and/or regional lymph node metastasis." .

obo:OBI_0002267 a obo:OBI_0002256 ;
  rdfs:label "pT3a (ovary)" ;
  rdfs:comment "A pathologic primary tumor stage for ovary according to AJCC 7th edition indicating that the tumor has microscopic peritoneal metastasis beyond pelvis." .

obo:OBI_0002268 a obo:OBI_0002256 ;
  rdfs:label "pT3b (ovary)" ;
  rdfs:comment "A pathologic primary tumor stage for ovary according to AJCC 7th edition indicating that the tumor has macroscopic peritoneal, metastatasis beyond pelvis, 2 cm or less in greatest dimension." .

obo:OBI_0002269 a obo:OBI_0002256 ;
  rdfs:label "pT3c (ovary)" ;
  rdfs:comment "A pathologic primary tumor stage for ovary according to AJCC 7th edition indicating that the tumor has peritoneal metastasis beyond pelvis, more than 2 cm in greatest dimension and/or regional lymph node metastasis." .

obo:OBI_0002232 a rdfs:Class ;
  rdfs:label "pathologic primary tumor stage for lung according to AJCC 7th edition" ;
  rdfs:comment "A categorical value specification that is a pathologic finding about one or more characteristics of lung cancer following the rules of the TNM American Joint Committee on Cancer (AJCC) version 7 classification system as they pertain to staging of the primary tumor. TNM pathologic primary tumor findings are based on clinical findings supplemented by histopathologic examination of one or more tissue specimens acquired during surgery." ;
  rdfs:subClassOf obo:OBI_0001930 .

obo:OBI_0002233 a obo:OBI_0002232 ;
  rdfs:label "pT0 (lung)" ;
  rdfs:comment "A pathologic primary tumor stage for lung according to AJCC 7th edition indicating that there is no evidence of primary tumor." .

obo:OBI_0002234 a obo:OBI_0002232 ;
  rdfs:label "pTis (lung)" ;
  rdfs:comment "A pathologic primary tumor stage for lung according to AJCC 7th edition indicating carcinoma in situ." .

obo:OBI_0002235 a obo:OBI_0002232 ;
  rdfs:label "pT1 (lung)" ;
  rdfs:comment "A pathologic primary tumor stage for lung according to AJCC 7th edition indicating that the tumor is 3 cm or less in greatest dimension, surrounded by lung or visceral pleura without bronchoscopic evidence of invasion more proximal than the lobar bronchus (i.e., not in the main bronchus)." .

obo:OBI_0002236 a obo:OBI_0002232 ;
  rdfs:label "pT1a (lung)" ;
  rdfs:comment "A pathologic primary tumor stage for lung according to AJCC 7th edition indicating that the tumor is 2 cm or less in greatest dimension." .

obo:OBI_0002237 a obo:OBI_0002232 ;
  rdfs:label "pT1b (lung)" ;
  rdfs:comment "A pathologic primary tumor stage for lung according to AJCC 7th edition indicating that the tumor is more than 2 cm but not more than 3 cm in greatest dimension." .

obo:OBI_0002238 a obo:OBI_0002232 ;
  rdfs:label "pT2 (lung)" ;
  rdfs:comment "A pathologic primary tumor stage for lung according to AJCC 7th edition indicating that the tumor is more than 3 cm but not more than 7 cm or the tumor has any of the following features: involves main bronchus, 2 cm or more distal to the carina, invades visceral pleura, associated with atelectasis or obstructive pneumonitis that extends to the hilar region but does not involve the entire lung." .

obo:OBI_0002239 a obo:OBI_0002232 ;
  rdfs:label "pT2a (lung)" ;
  rdfs:comment "A pathologic primary tumor stage for lung according to AJCC 7th edition indicating that the tumor is more than 3 cm but not more than 5 cm in greatest dimension." .

obo:OBI_0002240 a obo:OBI_0002232 ;
  rdfs:label "pT2b (lung)" ;
  rdfs:comment "A pathologic primary tumor stage for lung according to AJCC 7th edition indicating that the tumor is more than 5 cm but not more than 7 cm in greatest dimension." .

obo:OBI_0002241 a obo:OBI_0002232 ;
  rdfs:label "pT3 (lung)" ;
  rdfs:comment "A pathologic primary tumor stage for lung according to AJCC 7th edition indicating that the tumor is more than 7 cm or one that directly invades any of: parietal pleura, chest wall (including superior sulcus tumors), diaphragm, phrenic nerve, mediastinal pleura, parietal pericardiu or the tumor is in the main bronchus less than 2 cm distal to the carina but without  involvement of the carina or there is associated atelectasis or obstructive pneumonitis of the entire lung or there is separate tumor nodule(s) in the same lobe as the primary." .

obo:OBI_0002242 a obo:OBI_0002232 ;
  rdfs:label "pT4 (lung)" ;
  rdfs:comment "A pathologic primary tumor stage for lung according to AJCC 7th edition indicating that the tumor of any size that invades any of the following: mediastinum, heart, great vessels, trachea, recurrent laryngeal nerve, esophagus, vertebral body, carina or there is separate tumor nodule(s) in a different ipsilateral lobe to that of the primary." .
