PREFIX obo: <http://purl.obolibrary.org/obo/>
PREFIX rdf: <http://www.w3.org/1999/02/22-rdf-syntax-ns#>
PREFIX rdfs: <http://www.w3.org/2000/01/rdf-schema#>
PREFIX xsd: <http://www.w3.org/2001/XMLSchema#>

obo:OBCS_0000299 a rdfs:Class ;
  rdfs:label "standardize" ;
  rdfs:comment "definition to be confirmed" ;
  rdfs:subClassOf obo:OBCS_0000273 .

obo:BFO_0000062 a rdf:Property ;
  rdfs:label "preceded by"@en ;
  rdfs:comment "x is preceded by y if and only if the time point at which y ends is before or equivalent to the time point at which x starts. Formally: x preceded by y iff ω(y) <= α(x), where α is a function that maps a process to a start point, and ω is a function that maps a process to an end point."@en ;
  rdfs:domain obo:BFO_0000003 ;
  rdfs:range obo:BFO_0000003 ;
  rdfs:subPropertyOf obo:RO_0002086 .

obo:BFO_0000063 a rdf:Property ;
  rdfs:label "precedes"@en ;
  rdfs:comment "x precedes y if and only if the time point at which x ends is before or equivalent to the time point at which y starts. Formally: x precedes y iff ω(x) <= α(y), where α is a function that maps a process to a start point, and ω is a function that maps a process to an end point."@en ;
  rdfs:domain obo:BFO_0000003 ;
  rdfs:range obo:BFO_0000003 ;
  rdfs:subPropertyOf obo:RO_0002222 .

obo:BFO_0000066 a rdf:Property ;
  rdfs:label "occurs in"@en ;
  rdfs:comment "b occurs_in c =def b is a process and c is a material entity or immaterial entity& there exists a spatiotemporal region r and b occupies_spatiotemporal_region r.& forall(t) if b exists_at t then c exists_at t & there exist spatial regions s and s’ where & b spatially_projects_onto s at t& c is occupies_spatial_region s’ at t& s is a proper_continuant_part_of s’ at t"@en ;
  rdfs:domain obo:BFO_0000003 ;
  rdfs:range obo:BFO_0000004 .

obo:BFO_0000055 a rdf:Property ;
  rdfs:label "realizes"@en ;
  rdfs:comment "Paraphrase of elucidation: a relation between a process and a realizable entity, where there is some material entity that is bearer of the realizable entity and participates in the process, and the realizable entity comes to be realized in the course of the process" ;
  rdfs:domain obo:BFO_0000015 ;
  rdfs:range obo:BFO_0000017 .

obo:RO_0000057 a rdf:Property ;
  rdfs:label "has participant"@en ;
  rdfs:comment "a relation between a process and a continuant, in which the continuant is somehow involved in the process"@en ;
  rdfs:domain obo:BFO_0000003 ;
  rdfs:range obo:BFO_0000002 .

obo:OBCS_0000082 a rdfs:Class ;
  rdfs:label "statistical error" ;
  rdfs:comment "A quantitative confidence value that represents unexplained variation in a collection of observations; comopnents of error include random error and lack of fit error" ;
  rdfs:subClassOf obo:OBI_0000071 .

obo:OBI_0000312 a rdf:Property ;
  rdfs:label "is_specified_output_of"@en ;
  rdfs:comment "A relation between a planned process and a continuant participating in that process. The presence of the continuant at the end of the process is explicitly specified in the objective specification which the process realizes the concretization of."@en ;
  rdfs:domain obo:BFO_0000002 ;
  rdfs:range obo:BFO_0000003 ;
  rdfs:subPropertyOf obo:RO_0000056 .

obo:IAO_0000136 a rdf:Property ;
  rdfs:label "is about"@en ;
  rdfs:comment "A (currently) primitive relation that relates an information artifact to an entity."@en ;
  rdfs:range <https://w3id.org/linkml/Any> .

obo:RO_0000058 a rdf:Property ;
  rdfs:label "is concretized as"@en ;
  rdfs:comment "A relationship between a generically dependent continuant and a specifically dependent continuant, in which the generically dependent continuant depends on some independent continuant in virtue of the fact that the specifically dependent continuant also depends on that same independent continuant. A generically dependent continuant may be concretized as multiple specifically dependent continuants."@en ;
  rdfs:domain obo:BFO_0000031 ;
  rdfs:range obo:BFO_0000020 .

obo:RO_0000056 a rdf:Property ;
  rdfs:label "participates in"@en ;
  rdfs:comment "a relation between a continuant and a process, in which the continuant is somehow involved in the process"@en ;
  rdfs:domain obo:BFO_0000002 ;
  rdfs:range obo:BFO_0000003 .

obo:OBI_0000268 a rdfs:Class ;
  rdfs:label "organism feature identification objective"@en ;
  rdfs:comment "Organism_feature_identification_objective is a biological_feature_identification_objective role describing a study designed to examine or characterize a biological feature monitored at the level of the organism, e.g. height, weight, stage of development, stage of life cycle."@en ;
  rdfs:subClassOf obo:OBI_0000015 .

obo:BFO_0000034 a rdfs:Class ;
  rdfs:label "function"@en ;
  rdfs:subClassOf obo:BFO_0000016 .

obo:RO_0000079 a rdf:Property ;
  rdfs:label "function of"@en ;
  rdfs:comment "a relation between a function and an independent continuant (the bearer), in which the function specifically depends on the bearer for its existence"@en ;
  rdfs:domain obo:BFO_0000034 ;
  rdfs:range <https://w3id.org/linkml/Any> ;
  rdfs:subPropertyOf obo:RO_0000052 .

obo:BFO_0000054 a rdf:Property ;
  rdfs:label "realized in"@en ;
  rdfs:comment "Paraphrase of elucidation: a relation between a realizable entity and a process, where there is some material entity that is bearer of the realizable entity and participates in the process, and the realizable entity comes to be realized in the course of the process" ;
  rdfs:domain obo:BFO_0000017 ;
  rdfs:range obo:BFO_0000015 , obo:OBI_0000070 , obo:OBI_0000274 .

obo:RO_0000059 a rdf:Property ;
  rdfs:label "concretizes"@en ;
  rdfs:comment "A relationship between a specifically dependent continuant and a generically dependent continuant, in which the generically dependent continuant depends on some independent continuant in virtue of the fact that the specifically dependent continuant also depends on that same independent continuant. Multiple specifically dependent continuants can concretize the same generically dependent continuant."@en ;
  rdfs:domain obo:BFO_0000020 ;
  rdfs:range obo:BFO_0000031 .

obo:OBI_0003039 a rdfs:Class ;
  rdfs:label "feces microbiology assay" ;
  rdfs:comment "An organism detection assay that detects microorganisms in a feces specimen." ;
  rdfs:subClassOf obo:OBI_0003237 , obo:OBI_0003498 .

obo:OBI_0000417 a rdf:Property ;
  rdfs:label "achieves_planned_objective" ;
  rdfs:comment "This relation obtains between a planned process and a objective specification when the criteria specified in the objective specification are met at the end of the planned process." ;
  rdfs:range <https://w3id.org/linkml/Any> .

obo:OBI_0000293 a rdf:Property ;
  rdfs:label "has_specified_input"@en ;
  rdfs:comment "The inverse property of is_specified_input_of"@en ;
  rdfs:domain obo:BFO_0000003 ;
  rdfs:range obo:BFO_0000002 , obo:IAO_0000027 , obo:BFO_0000040 , obo:OBI_0000660 , obo:OBI_0000023 , obo:OBI_0000118 , obo:OBI_0000648 ;
  rdfs:subPropertyOf obo:RO_0000057 .

obo:OBI_0002465 a rdfs:Class ;
  rdfs:label "age since culture seeding measurement datum" ;
  rdfs:comment "An age measurement datum that is the result of the measurement of the age of a cell since cultured (the process of seeding cells onto a culture dish)." ;
  rdfs:subClassOf obo:OBI_0001167 .

obo:IAO_0000004 a rdf:Property ;
  rdfs:label "has measurement value"@en ;
  rdfs:range <https://w3id.org/linkml/Any> .

obo:IAO_0000413 a rdf:Property ;
  rdfs:label "is duration of"@en ;
  rdfs:comment "relates a process to a time-measurement-datum that represents the duration of the process"@en ;
  rdfs:range obo:BFO_0000015 ;
  rdfs:subPropertyOf obo:IAO_0000136 .

obo:IAO_0000039 a rdf:Property ;
  rdfs:label "has measurement unit label"@en ;
  rdfs:range obo:UO_0000003 , <https://w3id.org/linkml/Any> , obo:UO_0000002 ;
  rdfs:subPropertyOf obo:BFO_0000051 .

obo:IAO_0000221 a rdf:Property ;
  rdfs:label "is quality measurement of"@en ;
  rdfs:comment "m is a quality measurement of q at t. When q is a quality, there is a measurement process p that has specified output m, a measurement datum, that is about q"@en ;
  rdfs:range <https://w3id.org/linkml/Any> , obo:PATO_0000125 ;
  rdfs:subPropertyOf obo:IAO_0000136 .

obo:OBI_0002394 a rdfs:Class ;
  rdfs:label "number of pregnancies" ;
  rdfs:comment "A measurement datum of the total number of pregnancies a woman has had." ;
  rdfs:subClassOf obo:IAO_0000109 .

obo:OBI_0200147 a rdfs:Class ;
  rdfs:label "network graph quality calculation"@en ;
  rdfs:comment "A network analysis in which an input data set describing node objects and edge relationships between node objects is used to determine the output quality of the network as a whole."@en ;
  rdfs:subClassOf obo:OBI_0200080 .

obo:OBCS_0000194 a rdfs:Class ;
  rdfs:label "continuous data value"@en ;
  rdfs:comment "A data value that is continuous from an interval of possible outcomes." ;
  rdfs:subClassOf obo:OBCS_0000193 .

obo:SO_0000353 a rdfs:Class ;
  rdfs:label "sequence_assembly" ;
  rdfs:comment "A sequence of nucleotides that has been algorithmically derived from an alignment of two or more different sequences." ;
  rdfs:subClassOf obo:SO_0001248 .

obo:OBI_0003578 a rdfs:Class ;
  rdfs:label "bone marrow microbiology assay" ;
  rdfs:comment "An organism detection assay that detects microorganisms in a bone marrow specimen." ;
  rdfs:subClassOf obo:OBI_0003498 .

obo:OBI_0000299 a rdf:Property ;
  rdfs:label "has_specified_output"@en ;
  rdfs:comment "The inverse property of is_specified_output_of"@en ;
  rdfs:domain obo:BFO_0000003 ;
  rdfs:range obo:BFO_0000002 , obo:IAO_0000027 ;
  rdfs:subPropertyOf obo:RO_0000057 .

obo:OBI_0300310 a rdfs:Class ;
  rdfs:label "sequential design" ;
  rdfs:comment "Any design in which the decision as to whether to enroll the next patient, pair of patients, or block of patients is determined by whether the cumulative treatment difference for all previous patients is within specified limits.  Enrollment is continued if the difference does not exceed the limits.  It is terminated if it does" ;
  rdfs:subClassOf obo:OBI_0000115 .

obo:BFO_0000051 a rdf:Property ;
  rdfs:label "has part"@en ;
  rdfs:comment "a core relation that holds between a whole and its part"@en ;
  rdfs:range <https://w3id.org/linkml/Any> .

obo:OBI_0200056 a rdfs:Class ;
  rdfs:label "moving average"@en ;
  rdfs:comment "A moving average is a data transformation in which center calculations, usually mean calculations, are performed on values within a sliding window across the input data set."@en ;
  rdfs:subClassOf obo:APOLLO_SV_00000796 , obo:OBI_0200170 .

obo:OBCS_0000021 a rdfs:Class ;
  rdfs:label "Mendelian randomization" ;
  rdfs:comment "An inferential statistical data analysis that uses measured variation in genes of known function to examine the causal effect of a modifiable exposure on disease in non-experimental studies." ;
  rdfs:subClassOf obo:OBCS_0000121 .

obo:OBCS_0000112 a rdfs:Class ;
  rdfs:label "moderator variable" ;
  rdfs:comment "A statistical variable that specifies a variable affecting the direction and/or strength of the relation between dependent and independent variables; occurs when the relationship between two variables depends on a third variable" ;
  rdfs:subClassOf obo:OBCS_0000038 .

obo:OBI_0000094 a rdfs:Class ;
  rdfs:label "material processing"@en ;
  rdfs:comment "A planned process which results in physical changes in a specified input material"@en ;
  rdfs:subClassOf obo:OBI_0000011 .

obo:OBI_0003255 a rdfs:Class ;
  rdfs:label "endotracheal tube aspirate microbiology datum" ;
  rdfs:comment "An organism detection datum that is the specified output of an endotracheal tube aspirate microbiology assay." ;
  rdfs:subClassOf obo:OBI_0003064 , obo:OBI_0003254 .

obo:OBI_0000655 a rdfs:Class ;
  rdfs:label "blood specimen" ;
  rdfs:comment "a material entity derived from a portion of blood collected from an organism" ;
  rdfs:subClassOf obo:OBI_2000009 .

obo:RO_0001000 a rdf:Property ;
  rdfs:label "derives from"@en ;
  rdfs:comment "a relation between two distinct material entities, the new entity and the old entity, in which the new entity begins to exist when the old entity ceases to exist, and the new entity inherits the significant portion of the matter of the old entity"@en ;
  rdfs:range <https://w3id.org/linkml/Any> .

obo:RO_0000087 a rdf:Property ;
  rdfs:label "has role"@en ;
  rdfs:comment "a relation between an independent continuant (the bearer) and a role, in which the role specifically depends on the bearer for its existence"@en ;
  rdfs:domain obo:BFO_0000004 ;
  rdfs:range obo:BFO_0000023 ;
  rdfs:subPropertyOf obo:RO_0000053 .

obo:RO_0000085 a rdf:Property ;
  rdfs:label "has function"@en ;
  rdfs:comment "a relation between an independent continuant (the bearer) and a function, in which the function specifically depends on the bearer for its existence"@en ;
  rdfs:domain obo:BFO_0000004 ;
  rdfs:range obo:BFO_0000034 ;
  rdfs:subPropertyOf obo:RO_0000053 .

obo:RO_0000091 a rdf:Property ;
  rdfs:label "has disposition"@en ;
  rdfs:comment "a relation between an independent continuant (the bearer) and a disposition, in which the disposition specifically depends on the bearer for its existence"@en ;
  rdfs:domain obo:BFO_0000004 ;
  rdfs:range obo:BFO_0000016 ;
  rdfs:subPropertyOf obo:RO_0000053 .

obo:RO_0002002 a rdf:Property ;
  rdfs:label "has 2D boundary"@en ;
  rdfs:comment "a relation between a material entity and a 2D immaterial entity (the boundary), in which the boundary delimits the material entity"@en ;
  rdfs:domain obo:BFO_0000040 ;
  rdfs:range obo:BFO_0000141 .

obo:RO_0001025 a rdf:Property ;
  rdfs:label "located in"@en ;
  rdfs:comment "a relation between two independent continuants, the target and the location, in which the target is entirely within the location"@en ;
  rdfs:domain obo:BFO_0000004 ;
  rdfs:range <https://w3id.org/linkml/Any> .

obo:OBI_0003333 a rdfs:Class ;
  rdfs:label "computed image data set" ;
  rdfs:comment "An image data set that is the output of an image data set analysis." ;
  rdfs:subClassOf obo:OBCS_0000123 , obo:OBI_0003327 .

obo:RO_0002351 a rdf:Property ;
  rdfs:label "has member"@en ;
  rdfs:comment "has member is a mereological relation between a collection and an item." ;
  rdfs:range <https://w3id.org/linkml/Any> , obo:IAO_0000100 ;
  rdfs:subPropertyOf obo:BFO_0000051 .

obo:OBCS_0000223 a rdf:Property ;
  rdfs:label "has probability distribution"@en ;
  rdfs:comment "A relation between a data set and a probability distribution." ;
  rdfs:domain obo:IAO_0000100 ;
  rdfs:range obo:OBCS_0000010 .

obo:OBCS_0000315 a rdfs:Class ;
  rdfs:label "incomplete knowledge" ;
  rdfs:comment "definition to be confirmed" ;
  rdfs:subClassOf obo:OBCS_0000272 .

obo:BFO_0000017 a rdfs:Class ;
  rdfs:label "realizable entity"@en ;
  rdfs:comment "A specifically dependent continuant  that inheres in continuant  entities and are not exhibited in full at every time in which it inheres in an entity or group of entities. The exhibition or actualization of a realizable entity is a particular manifestation, functioning or process that occurs under certain circumstances."@en ;
  rdfs:subClassOf obo:BFO_0000020 .

obo:UBERON_0001988 a rdfs:Class ;
  rdfs:label "feces" ;
  rdfs:comment "Portion of semisolid bodily waste discharged through the anus[MW,modified]." ;
  rdfs:subClassOf obo:UBERON_0000174 .

obo:OBI_0200081 a rdfs:Class ;
  rdfs:label "sequence analysis objective"@en ;
  rdfs:comment "A sequence analysis objective is a data transformation objective which aims to analyse some ordered biological data for sequential patterns."@en ;
  rdfs:subClassOf obo:OBI_0200166 .

obo:OBI_0002580 a rdfs:Class ;
  rdfs:label "aligned sequence data" ;
  rdfs:comment "The results of a sequence alignment." ;
  rdfs:subClassOf obo:OBI_0000973 .

obo:OBI_0003067 a rdfs:Class ;
  rdfs:label "northing coordinate measurement datum" ;
  rdfs:comment "A one dimensional Cartesian spatial coordinate datum that is the northward component of a distance from a point on a map projection." ;
  rdfs:subClassOf obo:IAO_0000401 .

obo:IAO_0000404 a rdf:Property ;
  rdfs:label "has x coordinate value"@en ;
  rdfs:range <https://w3id.org/linkml/Any> .

obo:IAO_0000219 a rdf:Property ;
  rdfs:label "denotes"@en ;
  rdfs:comment "A primitive, instance-level, relation obtaining between an information content entity and some portion of reality. Denotation is what happens when someone creates an information content entity E in order to specifically refer to something. The only relation between E and the thing is that E can be used to 'pick out' the thing. This relation connects those two together. Freedictionary.com sense 3: To signify directly; refer to specifically"@en ;
  rdfs:range <https://w3id.org/linkml/Any> ;
  rdfs:subPropertyOf obo:IAO_0000136 .

obo:IAO_0000407 a rdf:Property ;
  rdfs:label "has coordinate unit label"@en ;
  rdfs:comment "relating a cartesian spatial coordinate datum to a unit label that together with the values represent a point"@en ;
  rdfs:range <https://w3id.org/linkml/Any> ;
  rdfs:subPropertyOf obo:BFO_0000051 .

obo:OBCS_0000106 a rdfs:Class ;
  rdfs:label "cohort study design" ;
  rdfs:comment "A study design that starts with an exposure and moves forward to the outcome of interest, even if the data are collected retrospectively. As an example, a group of patients who have variable exposure to a risk factor of interest can be followed over time for an outcome." ;
  rdfs:subClassOf obo:OBI_0500000 .

obo:OBI_0000355 a rdfs:Class ;
  rdfs:label "hypothesis driven investigation"@en ;
  rdfs:comment "is an investigation with the goal to test one or more hypothesis"@en ;
  rdfs:subClassOf obo:OBI_0000066 .

obo:UBERON_0000465 a rdfs:Class ;
  rdfs:label "material anatomical entity" ;
  rdfs:comment "Anatomical entity that has mass." ;
  rdfs:subClassOf obo:BFO_0000040 .

obo:OBCS_0000071 a rdfs:Class ;
  rdfs:label "credible interval" ;
  rdfs:comment "A quantitative confidence value that is used  in Bayesian analysis to describe the range in which a posterior probability estimate is likely to reside." ;
  rdfs:subClassOf obo:OBI_0000071 .

obo:OBI_0003283 a rdfs:Class ;
  rdfs:label "pleural fluid microbiology assay" ;
  rdfs:comment "An organism detection assay that detects microorganisms in a pleural fluid specimen." ;
  rdfs:subClassOf obo:OBI_0003498 .

obo:OBI_0001156 a rdfs:Class ;
  rdfs:label "age since planting measurement datum"@en ;
  rdfs:comment "An age measurement datum that is the result of the measurement of the age of an organism since planting, the process of placing a plant in media (e.g. soil) to allow it to grow, which excludes sowing." ;
  rdfs:subClassOf obo:OBI_0001167 .

obo:OBI_0500003 a rdfs:Class ;
  rdfs:label "cross over design" ;
  rdfs:comment "a repeated measure design which ensures that experimental units receive, in sequence, the treatment (or the control), and then, after a specified time interval (aka *wash-out periods*), switch to the control (or treatment). In this design, subjects (patients in human context) serve as their own controls, and randomization may be used to determine the ordering which a subject receives the treatment and control" ;
  rdfs:subClassOf obo:OBI_0500002 .

obo:OBI_0000970 a rdfs:Class ;
  rdfs:label "scalar score from composite inputs" ;
  rdfs:comment "A measurement datum which is the result of combining multiple datum. For example, a mean or summary score."@en ;
  rdfs:subClassOf obo:IAO_0000032 , obo:OBCS_0000233 .

obo:OBCS_0000123 a rdfs:Class ;
  rdfs:label "transformed data set"@en ;
  rdfs:comment "A data set that is produced as the output of a data transformation." ;
  rdfs:subClassOf obo:IAO_0000100 , obo:OBCS_0000233 .

obo:OBI_0200053 a rdfs:Class ;
  rdfs:label "expectation maximization"@en ;
  rdfs:comment "EM is a probabilistic algorithm used to estimate the maximum likelihood of parameters from existing data where the model involves unobserved latent variables. The input to this method is the data model for which the estimation is performed over and the output is an approximated probability function."@en ;
  rdfs:subClassOf obo:OBI_0200052 .

obo:OBI_0200160 a rdfs:Class ;
  rdfs:label "generalized family wise error rate correction method"@en ;
  rdfs:comment "A generalized FWER correction method is a multiple testing procedure that controls the probability of at least k+1 false positives, where k is a user-supplied integer." ;
  rdfs:subClassOf obo:OBI_0200089 .

obo:OBCS_0000133 a rdfs:Class ;
  rdfs:label "dependent variable"@en ;
  rdfs:comment "A statistical variable that represents the output or effect, or is tested to see if it is the effect in an experiment or a modeling." ;
  rdfs:subClassOf obo:OBCS_0000038 .

obo:OBCS_0000354 a rdfs:Class ;
  rdfs:label "model outcome uncertainty" ;
  rdfs:comment "This is the accumulated uncertainty caused by the uncertainties in all of the above locations (context, model, inputs, and parameters) that are propagated through the model and are reflected in the resulting estimates of the outcomes of interest." ;
  rdfs:subClassOf obo:OBCS_0000251 .

obo:PATO_0001421 a rdfs:Class ;
  rdfs:label "alive" ;
  rdfs:comment "A viability quality inhering in a bearer by virtue of the bearer's condition before death." ;
  rdfs:subClassOf obo:PATO_0000169 .

obo:OBCS_0000090 a rdfs:Class ;
  rdfs:label "interval scale" ;
  rdfs:comment "A measurement scale consisting of equal-sized units; the distance between any two positions is of known size." ;
  rdfs:subClassOf obo:OBCS_0000011 .

obo:IAO_0000009 a rdfs:Class ;
  rdfs:label "datum label"@en ;
  rdfs:comment "A label is a symbol that is part of some other datum and is used to either partially define  the denotation of that datum or to provide a means for identifying the datum as a member of the set of data with the same label"@en ;
  rdfs:subClassOf obo:IAO_0000030 .

obo:OBI_0000649 a rdfs:Class ;
  rdfs:label "data set of features"@en ;
  rdfs:comment "A data set that is produced as the output of a descriptive statistical calculation data transformation and consists of producing a data set that represents one or more features of interest about the input data set."@en ;
  rdfs:subClassOf obo:OBCS_0000123 , obo:OBCS_0000218 .

obo:OBCS_0000235 a rdfs:Class ;
  rdfs:label "medical test sensitivity disposition"@en ;
  rdfs:comment "A sensitivity disposition that is related to a medical test and inheres in a population of organism." ;
  rdfs:subClassOf obo:OBCS_0000214 .

obo:OBI_0003232 a rdfs:Class ;
  rdfs:label "cerebrospinal fluid assay" ;
  rdfs:comment "An assay that has a cerebrospinal fluid specimen as evaluant." ;
  rdfs:subClassOf obo:OBI_0000070 .

obo:OBI_0002771 a rdfs:Class ;
  rdfs:label "full karyotype information"@en ;
  rdfs:comment "A karyotype information that is about the structural variation of the whole genome."@en ;
  rdfs:subClassOf obo:OBI_0002769 .

obo:OBI_0200183 a rdfs:Class ;
  rdfs:label "scaling objective"@en ;
  rdfs:comment "is a data transformation objective where all, or some of a data set is adjusted by some data transformation according to some scale, for example a user defined minimum or maximum" ;
  rdfs:subClassOf obo:OBI_0200166 .

obo:OBCS_0000172 a rdfs:Class ;
  rdfs:label "data collection from online database"@en ;
  rdfs:comment "An online data collection process that extracts data from an online database" ;
  rdfs:subClassOf obo:OBCS_0000171 .

obo:STATO_0000243 a rdfs:Class ;
  rdfs:label "box and whisker plot"@en ;
  rdfs:comment "a box plot is a graph which plots datasets relying on their quartiles and the interquartile range to create the box and the whiskers."@en ;
  rdfs:subClassOf obo:IAO_0000038 .

obo:OBI_0003261 a rdfs:Class ;
  rdfs:label "bacteria in blood datum" ;
  rdfs:comment "A blood microbiology datum that is about bacteria." ;
  rdfs:subClassOf obo:OBI_0003244 .

obo:OBI_0200172 a rdfs:Class ;
  rdfs:label "partitioning objective"@en ;
  rdfs:comment "A partitioning objective is a data transformation objective where the aim is to generate a collection of disjoint non-empty subsets whose union equals a non-empty input set."@en ;
  rdfs:subClassOf obo:OBI_0200166 .

obo:OBI_0001933 a rdfs:Class ;
  rdfs:label "value specification" ;
  rdfs:comment "An information content entity that specifies a value within a classification scheme or on a quantitative scale." ;
  rdfs:subClassOf obo:IAO_0000030 .

obo:OBI_0200129 a rdfs:Class ;
  rdfs:label "node quality calculation"@en ;
  rdfs:comment "A network analysis in which an input data set describing node objects and edge relationships between node objects is used to determine the output quality of one of the node objects in the network."@en ;
  rdfs:subClassOf obo:OBI_0200080 .

obo:OBI_0000172 a rdfs:Class ;
  rdfs:label "parameter threshold"@en ;
  rdfs:comment "A measurement datum measuring the minimal signal that must be detected to generate an electrical event, as compared to the maximal detected signal in a flow cytometer instrument. The datum has a qualitative role"@en ;
  rdfs:subClassOf obo:IAO_0000109 .

obo:OBI_0000663 a rdfs:Class ;
  rdfs:label "class prediction data transformation"@en ;
  rdfs:comment "A class prediction data transformation (sometimes called supervised classification) is a data transformation that has objective class prediction."@en ;
  rdfs:subClassOf obo:OBCS_0000121 .

obo:OBCS_0000365 a rdfs:Class ;
  rdfs:label "uncertainty about long-term goal" ;
  rdfs:comment "classification to be confirmed" ;
  rdfs:subClassOf obo:OBCS_0000363 .

obo:OBCS_0000246 a rdfs:Class ;
  rdfs:label "Cochran–Mantel–Haenszel test"@en ;
  rdfs:comment "A chi square test that is used in the analysis of stratified or matched categorical data. It allows an investigator to test the association between a binary predictor or treatment and a binary outcome such as case or control status while taking into account the stratification. Unlike the McNemar test which can only handle pairs, the CMH test handles arbitrary strata size. It is named after William G. Cochran, Nathan Mantel and William Haenszel." ;
  rdfs:subClassOf obo:OBI_0200200 .

obo:OBI_0001966 a rdfs:Class ;
  rdfs:label "sequence library data demultiplexing"@en ;
  rdfs:comment "is a data transformation which uses sequence alignment and  'multiplex identifier sequence' information to separate all reads belonging to a given single sample following the sequencing of a multiplexed library"@en ;
  rdfs:subClassOf obo:OBI_0200187 .

obo:OBI_0200086 a rdfs:Class ;
  rdfs:label "spread calculation data transformation"@en ;
  rdfs:comment "A spread calculation is a data transformation that has objective spread calculation."@en ;
  rdfs:subClassOf obo:OBI_0200184 .

obo:OBI_0200182 a rdfs:Class ;
  rdfs:label "data vector reduction data transformation"@en ;
  rdfs:comment "A data vector reduction is a data transformation that has objective data vector reduction and that consists of reducing the input vectors k to a smaller number of output vectors j, where j<k."@en ;
  rdfs:subClassOf obo:OBI_0000707 .

obo:OBI_0001573 a rdfs:Class ;
  rdfs:label "DNA sequence data" ;
  rdfs:comment "A sequence data item that is about the primary structure of DNA" ;
  rdfs:subClassOf obo:OBI_0000973 .

obo:OBCS_0000207 a rdfs:Class ;
  rdfs:label "dummy variable"@en ;
  rdfs:comment "A quantitative variable can be transformed into a categorical variable, called a dummy variable by recoding the values" ;
  rdfs:subClassOf obo:OBCS_0000201 .

obo:OBI_0001940 a rdfs:Class ;
  rdfs:label "N50"@en ;
  rdfs:comment "the weighted median item size or N50 is a weighted median of the lengths of items, equal to the length of the longest item i such that the sum of the lengths of items greater than or equal in length to i is greater than or equal to half the length of all of the items. With regard to assemblies the items are typically contigs or scaffolds. It therefore denotes the ability of the software to create contigs and provides information about the resulting sequence assembly" ;
  rdfs:subClassOf obo:IAO_0000032 , obo:OBCS_0000233 .

obo:OBCS_0000224 a rdfs:Class ;
  rdfs:label "data set following probability distribution"@en ;
  rdfs:comment "A data set that follows a probability distribution"@en ;
  rdfs:subClassOf obo:IAO_0000100 .

obo:STATO_0000283 a rdfs:Class ;
  rdfs:label "negative binomial distribution"@en ;
  rdfs:comment "negative binomial probability distribution is a discrete probability distribution of the number of successes in a sequence of Bernoulli trials before a specified (non-random) number of failures (denoted r) occur. The negative binomial distribution, also known as the Pascal distribution or Pólya distribution, gives the probability of  r-1 successes and x  failures in x+r-1 trials, and success on the (x+r)th trial."@en ;
  rdfs:subClassOf obo:OBCS_0000067 .

obo:OBCS_0000227 a rdf:Property ;
  rdfs:label "has probability density function"@en ;
  rdfs:comment "A relation between a probability distribution and probability." ;
  rdfs:domain obo:OBCS_0000010 ;
  rdfs:range obo:OBCS_0000116 .

obo:OBI_0003244 a rdfs:Class ;
  rdfs:label "blood microbiology datum" ;
  rdfs:comment "An organism detection datum that is the specified output of a blood microbiology assay." ;
  rdfs:subClassOf obo:OBI_0003064 , obo:OBI_0003243 .

obo:BFO_0000145 a rdfs:Class ;
  rdfs:label "relational quality"@en ;
  rdfs:comment "b is a relational quality = Def. for some independent continuants c, d and for some time t: b quality_of c at t & b quality_of d at t. (axiom label in BFO2 Reference: [057-001])"@en ;
  rdfs:subClassOf obo:BFO_0000019 .

obo:OBCS_0000101 a rdfs:Class ;
  rdfs:label "type II error" ;
  rdfs:comment "A statistical error that the null hypothesis is false but has been accepted; a test result indicates that a condition failed, while it actually was successful." ;
  rdfs:subClassOf obo:OBCS_0000082 .

obo:OBI_0200070 a rdfs:Class ;
  rdfs:label "edge weighting"@en ;
  rdfs:comment "Edge weighting is the substitution or transformation of edge length using numerical data.  Data input include a symmetric adjacency matrix for a network and a second data set, for example a list of interactor pairs and a confidence score associated with the experimental detection of each pair's interaction.  Each element in the adjacency matrix is transformed or replaced with the corresponding number in the second data set.  Output data are a modified adjacency matrix reflecting the transformed state of the network."@en ;
  rdfs:subClassOf obo:OBI_0200080 .

obo:IAO_8000014 a rdfs:Class ;
  rdfs:label "generated ontology module"@en ;
  rdfs:comment "An ontology module that is automatically generated, for example via a SPARQL query or via template and a CSV."@en ;
  rdfs:subClassOf obo:IAO_8000000 .

obo:STATO_0000180 a rdfs:Class ;
  rdfs:label "standard normal distribution"@en ;
  rdfs:comment "standard normal distribution is a normal distribution with variance = 1 and mean=0"@en ;
  rdfs:subClassOf obo:OBCS_0000005 .

obo:OBI_0000832 a rdfs:Class ;
  rdfs:label "measurement device" ;
  rdfs:comment "A device in which a measure function inheres." ;
  rdfs:subClassOf obo:OBI_0000968 .

obo:IAO_0000416 a rdfs:Class ;
  rdfs:label "time measurement datum"@en ;
  rdfs:comment "A scalar measurement datum that is the result of measuring a temporal interval"@en ;
  rdfs:subClassOf obo:IAO_0000032 .

obo:OBCS_0000144 a rdfs:Class ;
  rdfs:label "R squared value"@en ;
  rdfs:comment "A quantitative confidence value that indicates how well data points fit a statistical model - sometimes simply a line or curve. It is a statistic used in the context of statistical models whose main purpose is either the prediction of future outcomes or the testing of hypotheses, on the basis of other related information. It provides a measure of how well observed outcomes are replicated by the model, as the proportion of total variation of outcomes explained by the model." ;
  rdfs:subClassOf obo:OBI_0000071 .

obo:OBCS_0000308 a rdfs:Class ;
  rdfs:label "observations limited to available material" ;
  rdfs:comment "definition to be confirmed" ;
  rdfs:subClassOf obo:OBCS_0000273 .

obo:OBI_0002565 a rdfs:Class ;
  rdfs:label "adapter-sequence trimming" ;
  rdfs:comment "A data transformation in which adapter sequences at the end of a molecular sequence are cut (removed)." ;
  rdfs:subClassOf obo:OBI_0002585 .

obo:OBI_0200116 a rdfs:Class ;
  rdfs:label "loess fitting"@en ;
  rdfs:comment "A loess fitting is a curve fitting obtained by localized regression. The latter refers to fitting a polynomial (straight line, quadratic, cubic, etc) to data values within a window covering a fraction of the total number of observations. As the window slides along the axis, a new polynomial is fit to the observations falling within the window. This continues until all points are fit with a local polynomial. The results are then smoothed together to form a curve. The smoothness of loess fits is controlled by a smoothing parameter (often denoted as alpha, usually between 1/4 and 1) and the degree of the polynomial that is fitted by the method (usually denoted by lambda)."@en ;
  rdfs:subClassOf obo:OBI_0200072 .

obo:OBCS_0000060 a rdfs:Class ;
  rdfs:label "validity" ;
  rdfs:comment "A data item that refers to the extent to which a concept conclusion or measurement is well-founded and corresponds accurately to the real world." ;
  rdfs:subClassOf obo:OBCS_0000220 .

obo:OBI_0001548 a rdfs:Class ;
  rdfs:label "equilibrium association constant (KA)" ;
  rdfs:comment "A binding constant defined as the ratio of koff over kon (off-rate of binding divided by on-rate)" ;
  rdfs:subClassOf obo:OBI_0001144 .

obo:OBI_0200042 a rdfs:Class ;
  rdfs:label "hierarchical clustering"@en ;
  rdfs:comment "A hierarchical clustering is a data transformation which achieves a class discovery objective, which takes as input data item and builds a hierarchy of clusters. The traditional representation of this hierarchy is a tree (visualized by a dendrogram), with the individual input objects at one end (leaves) and a single cluster containing every object at the other (root)."@en ;
  rdfs:subClassOf obo:APOLLO_SV_00000796 , obo:OBI_0200175 .

obo:OBCS_0000213 a rdfs:Class ;
  rdfs:label "relational graph"@en ;
  rdfs:comment "A mathematic graph that a set of objects (vertices or nodes) that are connected via numerous semantic relations." ;
  rdfs:subClassOf obo:OBCS_0000216 .

obo:IAO_8000003 a rdfs:Class ;
  rdfs:label "main release ontology module"@en ;
  rdfs:comment "An ontology module that is intended to be the primary release product and the one consumed by the majority of tools."@en ;
  rdfs:subClassOf obo:IAO_8000000 .

obo:OBCS_0000010 a rdfs:Class ;
  rdfs:label "probability distribution" ;
  rdfs:comment "An information content entity that refers to a distribution of a random variable that can be described using a mathematical formula." ;
  rdfs:subClassOf obo:IAO_0000030 .

obo:OBCS_0000183 a rdfs:Class ;
  rdfs:label "Bayesian analysis"@en ;
  rdfs:comment "An inferential statistical data analysis that estimates parameters of an underlying distribution based on the observed distribution" ;
  rdfs:subClassOf obo:OBCS_0000121 .

obo:OBI_0200105 a rdfs:Class ;
  rdfs:label "partial least square regression analysis"@en ;
  rdfs:comment """Partial least squares regression is an extension of the multiple linear regression model (see, e.g., Multiple Regression or General Stepwise Regression). In its simplest form, a linear model specifies the (linear) relationship between a dependent (response) variable Y, and a set of predictor variables, the X's, so that
Y = b0 + b1X1 + b2X2 + ... + bpXp
In this equation b0 is the regression coefficient for the intercept and the bi values are the regression coefficients (for variables 1 through p) computed from the data."""@en ;
  rdfs:subClassOf obo:OBI_0200102 .

obo:OBCS_0000040 a rdfs:Class ;
  rdfs:label "covariate specification" ;
  rdfs:comment "A variable specification that specifies a variable used in statistical analysis to correct, adjust, or modify the values of a dependent variable; an independent variable not manipulated by the investigator" ;
  rdfs:subClassOf obo:IAO_0000033 .

obo:OBI_0200113 a rdfs:Class ;
  rdfs:label "similarity calculation"@en ;
  rdfs:comment "A similarity calculation is a data transformation that attaches to each pair of objects in the input a number that is meant to reflect how 'close' or 'similar' those objects are."@en ;
  rdfs:subClassOf obo:APOLLO_SV_00000796 , obo:OBI_0000663 , obo:OBI_0200175 .

obo:OBCS_0000137 a rdfs:Class ;
  rdfs:label "data collection design"@en ;
  rdfs:comment "A plan specification that provides a detailed outline of how data is collected." ;
  rdfs:subClassOf obo:IAO_0000104 .

obo:OBI_0002584 a rdfs:Class ;
  rdfs:label "differential expression analysis data" ;
  rdfs:comment "The results of a differential expression analysis." ;
  rdfs:subClassOf obo:IAO_0000100 .

obo:OBCS_0000063 a rdfs:Class ;
  rdfs:label "random selection" ;
  rdfs:comment "A data collection by sampling process that uses some form of random selection, that is, one that will ensure that all units in the population have an equal probability or chance of being selected." ;
  rdfs:subClassOf obo:OBCS_0000132 .

obo:OBI_0200136 a rdfs:Class ;
  rdfs:label "edge betweenness calculation"@en ;
  rdfs:comment "An edge quality calculation in which the input is a data sets of shortest paths between all pairs of node in the network and the output is the sum of all shortest paths that traverse the specific edge."@en ;
  rdfs:subClassOf obo:OBI_0200135 .

obo:OBI_0200194 a rdfs:Class ;
  rdfs:label "survival analysis data transformation" ;
  rdfs:comment "A data transformation which has the objective of performing survival analysis." ;
  rdfs:subClassOf obo:OBI_0200000 .

obo:OBI_0000792 a rdfs:Class ;
  rdfs:label "statistical model validation" ;
  rdfs:comment "A data transformation which assesses how the results of a statistical analysis will generalize to an independent data set." ;
  rdfs:subClassOf obo:OBCS_0000121 , obo:OBI_0200171 .

obo:IAO_0000183 a rdfs:Class ;
  rdfs:label "dendrogram"@en ;
  rdfs:comment """A dendrogram is a report graph which is a tree diagram
frequently used to illustrate the arrangement of the clusters produced by a
clustering algorithm."""@en ;
  rdfs:subClassOf obo:IAO_0000038 .

obo:OBI_0500000 a rdfs:Class ;
  rdfs:label "study design"@en ;
  rdfs:comment "A plan specification comprised of protocols (which may specify how and what kinds of data will be gathered) that are executed as part of an investigation and is realized during a study design execution." ;
  rdfs:subClassOf obo:IAO_0000104 .

obo:OBCS_0000319 a rdfs:Class ;
  rdfs:label "inherent randomness of nature" ;
  rdfs:comment "the chaotic and unpredictable nature of natural processes" ;
  rdfs:subClassOf obo:OBCS_0000272 .

obo:OBI_0003063 a rdfs:Class ;
  rdfs:label "insecticide resistance datum" ;
  rdfs:comment "A data item that is about resistance to an insecticide." ;
  rdfs:subClassOf obo:IAO_0000027 .

obo:PATO_0000169 a rdfs:Class ;
  rdfs:label "viability" ;
  rdfs:comment "An organismal quality inhering in a bearer or a population by virtue of the bearer's disposition to survive and develop normally or the number of surviving individuals in a given population." ;
  rdfs:subClassOf obo:PATO_0001995 .

obo:OBI_0001872 a rdfs:Class ;
  rdfs:label "sequence assembly process"@en ;
  rdfs:comment "A data transformation that assembles two or more individual sequence reads into contiguous sequences (i.e., contigs)." ;
  rdfs:subClassOf obo:OBI_0200000 .

obo:OBI_0200064 a rdfs:Class ;
  rdfs:label "centroid mass spectrum analysis"@en ;
  rdfs:comment "A centroid mass spectrum is a data transformation in which many points are used to delineate a mass spectral peak, is converted into mass-centroided data by a data compression algorithm. The centroided mass peak is located at the weighted center of mass of the profile peak. The normalized area of the peak provides the mass intensity data."@en ;
  rdfs:subClassOf obo:OBI_0200085 .

obo:BFO_0000030 a rdfs:Class ;
  rdfs:label "object"@en ;
  rdfs:subClassOf obo:BFO_0000040 .

obo:STATO_0000186 a rdfs:Class ;
  rdfs:label "Lineweaver-Burk plot"@en ;
  rdfs:comment """Lineweaver-Burk plot is a graph which  is the graphical representation of the Lineweaver–Burk equation of enzyme kinetics, described by Hans Lineweaver and Dean Burk in 1934. The plot provides a useful graphical method for analysis of the Michaelis–Menten equation.
It was widely used to determine important terms in enzymology and enzyme kinetics as  the x-intercept of the graph represents −1/Km and the y-intercept of such a graph is equivalent to the inverse of Vmax"""@en ;
  rdfs:subClassOf obo:IAO_0000038 .

obo:OBCS_0000096 a rdfs:Class ;
  rdfs:label "fixed effect" ;
  rdfs:comment "A statistical effect that is associated with an input variable that has a limited number of levels or in which only a limited number of levels are of interest to the experimenter." ;
  rdfs:subClassOf obo:OBCS_0000037 .

obo:OBCS_0000281 a rdfs:Class ;
  rdfs:label "unclear boundaries of causal phenomena" ;
  rdfs:comment "definition to be confirmed" ;
  rdfs:subClassOf obo:OBCS_0000272 .

obo:OBI_0001554 a rdfs:Class ;
  rdfs:label "rate measurement datum" ;
  rdfs:comment "A scalar measurement datum that represents the number of events occuring over a time interval" ;
  rdfs:subClassOf obo:IAO_0000032 .

obo:OBI_0003593 a rdfs:Class ;
  rdfs:label "physician's global assessment of disease activity"@en ;
  rdfs:comment "A clinical data item that quantifies a physician's judgement of the overall activity of some specific disease in a patient." ;
  rdfs:subClassOf obo:OGMS_0000123 .

obo:OBI_0003266 a rdfs:Class ;
  rdfs:label "virus in feces datum" ;
  rdfs:comment "A feces microbiology datum that is about a virus." ;
  rdfs:subClassOf obo:OBI_0003246 .

obo:OGMS_0000123 a rdfs:Class ;
  rdfs:label "clinical data item"@en ;
  rdfs:comment "A data item that is about a patient and is the specified output of a health care process assay or diagnostic process" ;
  rdfs:subClassOf obo:IAO_0000027 .

obo:OBCS_0000256 a rdfs:Class ;
  rdfs:label "subjective process" ;
  rdfs:comment "A process refers to the mental processes involved in gaining knowledge and comprehension. Some of the many different cognitive processes include thinking, knowing, remembering, judging, and problem-solving." ;
  rdfs:subClassOf obo:BFO_0000015 .

obo:STATO_0000147 a rdfs:Class ;
  rdfs:label "LD plot"@en ;
  rdfs:comment "Linkage Disequilibrium plot is a graph which represents pairwise linkage disequilibrium measures between SNP as a heatmap"@en ;
  rdfs:subClassOf obo:IAO_0000038 .

obo:OBI_0000931 a rdfs:Class ;
  rdfs:label "study intervention" ;
  rdfs:comment "A planned process that is the part of the execution of an intervention design study which is varied between two or more subjects in the study." ;
  rdfs:subClassOf obo:OBI_0000011 .

obo:OBCS_0000360 a rdfs:Class ;
  rdfs:label "proprietary uncertainty" ;
  rdfs:comment "Proprietary uncertainty occurs due to the fact that information and knowledge about an issue are not uniformly shared among all those who could potentially use it. That is, some people or groups have information that others don't and may assert ownership or control over it. \"Proprietary uncertainty becomes most salient when it is necessary to reconcile the general needs for safety, health, and environment protection with more sectorial needs pertaining, for instance, to industrial production and process, or to licensing and control procedures\" (De Marchi, 1994). De Marchi notes that 'whistle blowing' is another source of proprietary uncertainty in that there is a need for protection of those who act in sharing information for the public good. Proprietary uncertainty would typically be high when knowledge plays a key role in assessment, but is not widely shared among participants. An example of such would be the case of external safety of military nuclear production facilities." ;
  rdfs:subClassOf obo:OBCS_0000251 .

obo:OBCS_0000201 a rdfs:Class ;
  rdfs:label "discrete variable"@en ;
  rdfs:comment "A statistical variable over a particular range of real values is one for which, for any value in the range that the variable is permitted to take on, there is a positive minimum distance to the nearest other permissible value." ;
  rdfs:subClassOf obo:OBCS_0000038 .

obo:OBI_0200075 a rdfs:Class ;
  rdfs:label "row submatrix extraction"@en ;
  rdfs:comment "A row submatrix extraction is a submatrix extraction where all the columns of the input matrix are retained and selection only occurs on the rows."@en ;
  rdfs:subClassOf obo:OBI_0200074 .

obo:OBCS_0000220 a rdfs:Class ;
  rdfs:label "derived data from inferential statistical analysis"@en ;
  rdfs:comment "A data item that is derived from an inferential statistical data analysis." ;
  rdfs:subClassOf obo:IAO_0000027 , obo:OBCS_0000218 .

obo:OBCS_0000148 a rdfs:Class ;
  rdfs:label "Wilcoxon signed-rank test"@en ;
  rdfs:comment "An inferential statistical data analysis used when comparing two related samples, matched samples, or repeated measurements on a single sample to assess whether their population mean ranks differ (i.e. it is a paired difference test). It can be used as an alternative to the paired Student's t-test, t-test for matched pairs, or the t-test for dependent samples when the population cannot be assumed to be normally distributed." ;
  rdfs:subClassOf obo:OBCS_0000236 .

obo:OBI_0200193 a rdfs:Class ;
  rdfs:label "background corrected data visualization" ;
  rdfs:comment "A data visualization which has input of a background corrected data set and produces an output of a report graph which is capable of rendering data of this type." ;
  rdfs:subClassOf obo:OBI_0200111 .

obo:OBCS_0000304 a rdfs:Class ;
  rdfs:label "search for pathognomonic sign" ;
  rdfs:comment "definition to be confirmed" ;
  rdfs:subClassOf obo:OBCS_0000273 .

obo:BFO_0000182 a rdfs:Class ;
  rdfs:label "history"@en ;
  rdfs:subClassOf obo:BFO_0000015 .

obo:OBCS_0000052 a rdfs:Class ;
  rdfs:label "Incidence rate" ;
  rdfs:comment "A data item that refers to the number of new events that have occurred in a specific time interval divided by the population at risk at the beginning of the time interval. The result gives the likelihood of developing an event in that time interval." ;
  rdfs:subClassOf obo:OBCS_0000220 .

obo:OBCS_0000203 a rdfs:Class ;
  rdfs:label "continuous ordinal variable"@en ;
  rdfs:comment "A continuous variable that occur when the measurement is continuous" ;
  rdfs:subClassOf obo:OBCS_0000200 .

obo:OBI_0000976 a rdfs:Class ;
  rdfs:label "handedness categorical measurement datum" ;
  rdfs:comment "A datum used to record the answer to a self assessment of whether a person uses their left hand, right hand primarily or each hand equally" ;
  rdfs:subClassOf obo:OBI_0000938 .

obo:OBI_0001938 a rdf:Property ;
  rdfs:label "has value specification" ;
  rdfs:comment "A relation between an information content entity and a value specification that specifies its value." ;
  rdfs:range <https://w3id.org/linkml/Any> ;
  rdfs:subPropertyOf obo:BFO_0000051 .

obo:OBI_0001151 a rdfs:Class ;
  rdfs:label "genetically modified material"@en ;
  rdfs:comment "a material entity, organism or cell,  that is the output of a genetic transformation process."@en ;
  rdfs:subClassOf obo:OBI_0000047 .

obo:OBI_0200120 a rdfs:Class ;
  rdfs:label "variance calculation"@en ;
  rdfs:comment "A variance calculation is a descriptive statistics calculation in which the variance is defined as the average squared distance of each observation in the data set to the mean of the data set.  It is also known as the second central moment."@en ;
  rdfs:subClassOf obo:OBI_0200086 .

obo:OBI_0002505 a rdfs:Class ;
  rdfs:label "milk specimen" ;
  rdfs:comment "A specimen that is derived from milk." ;
  rdfs:subClassOf obo:OBI_2000009 .

obo:OBCS_0000197 a rdfs:Class ;
  rdfs:label "cardinal data value"@en ;
  rdfs:comment "A data value that is a cardinal number, i.e., a number that says how many of something there are, such as one, two, three, four, five." ;
  rdfs:subClassOf obo:OBCS_0000193 .

obo:BFO_0000006 a rdfs:Class ;
  rdfs:label "spatial region"@en ;
  rdfs:subClassOf obo:BFO_0000141 .

obo:OBI_0000674 a rdfs:Class ;
  rdfs:label "center value"@en ;
  rdfs:comment "A data item that is produced as the output of a center calculation data transformation and represents the center value of the input data."@en ;
  rdfs:subClassOf obo:OBCS_0000219 , obo:OBI_0000649 .

obo:OBI_0001167 a rdfs:Class ;
  rdfs:label "age measurement datum"@en ;
  rdfs:comment "A time measurement datum that is the result of measurement of age of an organism" ;
  rdfs:subClassOf obo:IAO_0000416 .

obo:OBCS_0000270 a rdfs:Class ;
  rdfs:label "critical review of assumptions in model" ;
  rdfs:comment "A method that enables to systematically identify and prioritize critical assumptions in (chains of linked) models and provides a framework for the critical appraisal of model assumptions.This method aims to systematically identify, prioritise and analyse importance and strength of assumptions in models." ;
  rdfs:subClassOf obo:OBCS_0000258 .

obo:OBI_0002476 a rdfs:Class ;
  rdfs:label "number of rounds of amplification"@en ;
  rdfs:comment "A data item that is the number of times an amplification reaction happened."@en ;
  rdfs:subClassOf obo:IAO_0000027 .

obo:OBI_0200168 a rdfs:Class ;
  rdfs:label "correction objective"@en ;
  rdfs:comment "A correction objective is a data transformation objective where the aim is to correct for error, noise or other impairments to the input of the data transformation or derived from the data transformation itself"@en ;
  rdfs:subClassOf obo:OBI_0200166 .

obo:UBERON_0000178 a rdfs:Class ;
  rdfs:label "blood" ;
  rdfs:comment "A fluid that is composed of blood plasma and erythrocytes." ;
  rdfs:subClassOf obo:PR_000050567 , obo:UBERON_0006314 .

obo:STATO_0000125 a rdfs:Class ;
  rdfs:label "Wilkinson dot plot" ;
  rdfs:comment "The dot plot as a representation of a distribution consists of group of data points plotted on a simple scale. Dot plots are used for continuous, quantitative, univariate data. Data points may be labelled if there are few of them."@en ;
  rdfs:subClassOf obo:IAO_0000037 .

obo:UBERON_0001729 a rdfs:Class ;
  rdfs:label "oropharynx" ;
  rdfs:comment "The portion of the pharynx that lies between the soft palate and the upper edge of the epiglottis." ;
  rdfs:subClassOf obo:UBERON_0004119 , obo:UBERON_0013522 .

obo:OBI_0666667 a rdfs:Class ;
  rdfs:label "nucleic acid extraction"@en ;
  rdfs:comment "a material separation to recover the nucleic acid fraction of an input material"@en ;
  rdfs:subClassOf obo:OBI_0302884 .

obo:OBI_0200125 a rdfs:Class ;
  rdfs:label "data combination"@en ;
  rdfs:comment "A data transformation in which individual input data elements and values are merged together into a output set of data elements and values."@en ;
  rdfs:subClassOf obo:OBI_0200000 .

obo:IAO_8000000 a rdfs:Class ;
  rdfs:label "ontology module"@en ;
  rdfs:subClassOf obo:IAO_0000102 .

obo:OBI_0000047 a rdfs:Class ;
  rdfs:label "processed material"@en ;
  rdfs:comment "Is a material entity that is created or changed during material processing."@en ;
  rdfs:subClassOf obo:BFO_0000040 .

obo:OBCS_0000267 a rdfs:Class ;
  rdfs:label "scenario analysis" ;
  rdfs:comment "A method that tries to describe logical and internally consistent sequences  of events to explore how the future might, could or should evolve from the past and present." ;
  rdfs:subClassOf obo:OBCS_0000258 .

obo:OBI_0200102 a rdfs:Class ;
  rdfs:label "regression analysis method"@en ;
  rdfs:comment "Regression analysis is a descriptive statistics technique that examines the relation of a dependent variable (response variable) to specified independent variables (explanatory variables). Regression analysis can be used as a descriptive method of data analysis (such as curve fitting) without relying on any assumptions about underlying processes generating the data."@en ;
  rdfs:subClassOf obo:OBCS_0000121 .

obo:OBI_0002980 a rdfs:Class ;
  rdfs:label "reference protein sequence stop site" ;
  rdfs:comment "The position of the last amino acid in a reference protein sequence (sequence being used for comparison)." ;
  rdfs:subClassOf obo:OBI_0000973 .

obo:OBI_0003056 a rdfs:Class ;
  rdfs:label "proportion mapped reads" ;
  rdfs:comment "A sequence datum that is the specified output of a read mapping and is the ratio of the count of mapped reads to the total count of reads." ;
  rdfs:subClassOf obo:OBI_0000973 .

obo:UBERON_0001359 a rdfs:Class ;
  rdfs:label "cerebrospinal fluid" ;
  rdfs:comment "A clear, colorless, bodily fluid, that occupies the subarachnoid space and the ventricular system around and inside the brain and spinal cord." ;
  rdfs:subClassOf obo:UBERON_0007779 .

obo:STATO_0000017 a rdfs:Class ;
  rdfs:label "Wilk's lambda distribution"@en ;
  rdfs:comment "Wilks' lambda distribution (named for Samuel S. Wilks), is a probability distribution used in multivariate hypothesis testing, especially with regard to the likelihood-ratio test and Multivariate analysis of variance. It is a multivariate generalization of the univariate F-distribution, and generalizes the F-distribution in the same way that the Hotelling's T-squared distribution generalizes Student's t-distribution."@en ;
  rdfs:subClassOf obo:OBCS_0000010 .

obo:IAO_0000403 a rdfs:Class ;
  rdfs:label "three dimensional cartesian spatial coordinate datum"@en ;
  rdfs:comment "A cartesion spatial coordinate datum that  uses three values to specify a position within a three dimensional spatial region"@en ;
  rdfs:subClassOf obo:IAO_0000400 .

obo:IAO_0000405 a rdf:Property ;
  rdfs:label "has z coordinate value"@en ;
  rdfs:range <https://w3id.org/linkml/Any> .

obo:IAO_0000406 a rdf:Property ;
  rdfs:label "has y coordinate value"@en ;
  rdfs:range <https://w3id.org/linkml/Any> .

obo:OBI_0002602 a rdfs:Class ;
  rdfs:label "multiplexed sequence data" ;
  rdfs:comment "Sequence data from a sequence library generated from at least two different sources, where each read in the sequence data includes base calls from a multiplex identifier sequence that can be used to trace the source of the read to its source." ;
  rdfs:subClassOf obo:OBI_0000973 .

obo:PATO_0001018 a rdfs:Class ;
  rdfs:label "physical quality" ;
  rdfs:comment "A quality of a physical entity that exists through action of continuants at the physical level of organisation in relation to other entities." ;
  rdfs:subClassOf obo:PATO_0001241 .

obo:OBI_0002388 a rdfs:Class ;
  rdfs:label "diagnosis of HIV" ;
  rdfs:comment "A diagnosis of infectious disease caused by the human immunodeficiency virus (1 or 2)." ;
  rdfs:subClassOf obo:OBI_0002385 .

obo:OBCS_0000159 a rdfs:Class ;
  rdfs:label "criterion validity"@en ;
  rdfs:comment "A test validity that refers to the correlation between the test and a criterion variable (or variables) taken as representative of the construct. In other words, it compares the test with other measures or outcomes (the criteria) already held to be valid. For example, employee selection tests are often validated against measures of job performance (the criterion), and IQ tests are often validated against measures of academic performance (the criterion)." ;
  rdfs:subClassOf obo:OBCS_0000053 .

obo:OGMS_0000073 a rdfs:Class ;
  rdfs:label "diagnosis" ;
  rdfs:comment "The representation of a conclusion of a diagnostic process."@en ;
  rdfs:subClassOf obo:OGMS_0000123 .

obo:IAO_8000018 a rdfs:Class ;
  rdfs:label "obo basic subset ontology module"@en ;
  rdfs:comment """A subset ontology that is designed for basic applications to continue to make certain simplifying assumptions; many of these simplifying assumptions were based on the initial version of the Gene Ontology, and have become enshrined in many popular and useful tools such as term enrichment tools.

Examples of such assumptions include: traversing the ontology graph ignoring relationship types using a naive algorithm will not lead to cycles (i.e. the ontology is a DAG); every referenced term is declared in the ontology (i.e. there are no dangling clauses).

An ontology is OBO Basic if and only if it has the following characteristics:
DAG
Unidirectional
No Dangling Clauses
Fully Asserted
Fully Labeled
No equivalence axioms
Singly labeled edges
No qualifier lists
No disjointness axioms
No owl-axioms header
No imports"""@en ;
  rdfs:seeAlso <http://owlcollab.github.io/oboformat/doc/obo-syntax.html#6.2> ;
  rdfs:subClassOf obo:IAO_8000017 .

obo:OBI_0003277 a rdfs:Class ;
  rdfs:label "virus in nasopharyngeal or oropharyngeal swab datum" ;
  rdfs:comment "A nasopharyngeal or oropharyngeal swab microbiology datum that is about a virus." ;
  rdfs:subClassOf obo:OBI_0003257 .

obo:OBI_0000023 a rdfs:Class ;
  rdfs:label "classified data set"@en ;
  rdfs:comment "A data set that is produced as the output of a class prediction data transformation and consists of a data set with assigned class labels."@en ;
  rdfs:subClassOf obo:OBCS_0000123 , obo:OBCS_0000220 .

obo:OBI_0302884 a rdfs:Class ;
  rdfs:label "extraction"@en ;
  rdfs:comment "A material separation in which a desired component of an input material is separated from the remainder" ;
  rdfs:subClassOf obo:OBI_0600014 .

obo:BFO_0000029 a rdfs:Class ;
  rdfs:label "site"@en ;
  rdfs:subClassOf obo:BFO_0000141 .

obo:OBCS_0000078 a rdfs:Class ;
  rdfs:label "type 1 error rate" ;
  rdfs:comment "A quantitative confidence value that refers to the probability of incorrectly concluding that there is a statistically significant difference in a dataset. Alpha is the number after a p-value. Thus, a statistically significant difference reported as p<0.05 means that there is less than a 5 percent chance that the difference could have occurred by chance." ;
  rdfs:subClassOf obo:OBI_0000071 .

obo:IAO_0000593 a rdfs:Class ;
  rdfs:label "software library"@en ;
  rdfs:comment "A software library is software composed of a collection of software modules and/or software methods in a form that can be statically or dynamically linked to some software application."@en ;
  rdfs:subClassOf obo:IAO_0000010 .

obo:OBI_0000861 a rdfs:Class ;
  rdfs:label "Likelihood-ratio test" ;
  rdfs:comment "Likelihood-ratio is a data transformation which tests whether there is evidence of the need to move from a simple model to a more complicated one (where the simple model is nested within the complicated one); tests of the goodness-of-fit between two models." ;
  rdfs:subClassOf obo:OBCS_0000121 .

obo:UO_0000003 a rdfs:Class ;
  rdfs:label "time unit" ;
  rdfs:subClassOf obo:IAO_0000003 .

obo:OBCS_0000067 a rdfs:Class ;
  rdfs:label "discrete probability distribution" ;
  rdfs:comment "A probability distribution that is associated with discrete variables and is characterized by a probability mass function." ;
  rdfs:subClassOf obo:OBCS_0000010 .

obo:OBI_2000013 a rdfs:Class ;
  rdfs:label "arterial blood specimen" ;
  rdfs:comment "A specimen that is derived from some arterial blood" ;
  rdfs:subClassOf obo:OBI_2000009 .

obo:OBI_0200187 a rdfs:Class ;
  rdfs:label "sequence analysis data transformation"@en ;
  rdfs:comment "A sequence analysis data transformation is a data transformation that has objective sequence analysis and has the aim of analysing ordered biological data for sequential patterns."@en ;
  rdfs:subClassOf obo:OBI_0200000 .

obo:IAO_8000010 a rdfs:Class ;
  rdfs:label "exclusion subset ontology module"@en ;
  rdfs:comment "A subset of an ontology that is intended to be excluded for some purpose. For example, a blacklist of classes."@en ;
  rdfs:subClassOf obo:IAO_8000006 .

obo:OBI_0002483 a rdfs:Class ;
  rdfs:label "spike-in dilution factor"@en ;
  rdfs:comment "A data item that indicates the dilution of spike-in added to a specimen."@en ;
  rdfs:subClassOf obo:IAO_0000027 .

obo:OBCS_0000009 a rdfs:Class ;
  rdfs:label "point biserial correlation" ;
  rdfs:comment "A special case of the Pearson product-moment correlation; calculated when either the independent variable or dependent variable is dichotomous while the other variable is non-dichotomous" ;
  rdfs:subClassOf obo:OBCS_0000019 .

obo:OBCS_0000166 a rdfs:Class ;
  rdfs:label "GLobal Identifier of Target Regions software"@en ;
  rdfs:comment "A software that is used to identify  transcription factor binding sites in a genome that have been enriched with aligned reads generated from ChIP-Seq technology." ;
  rdfs:subClassOf obo:IAO_0000010 .

obo:OBI_0200157 a rdfs:Class ;
  rdfs:label "data vector reduction objective"@en ;
  rdfs:comment "Data vector reduction is a data transformation objective in which k m-dimensional input vectors are reduced to j m-dimensional output vectors, where j is smaller than k."@en ;
  rdfs:subClassOf obo:OBI_0200166 .

obo:OBI_0000739 a rdfs:Class ;
  rdfs:label "Student's t-test" ;
  rdfs:comment "Studen't t-test is a data transformation with the objective of a statistical hypothesis test in which the test statistic has a Student's t distribution if the null hypothesis is true. It is applied when the population is assumed to be normally distributed but the sample sizes are small enough that the statistic on which inference is based is not normally distributed because it relies on an uncertain estimate of standard deviation rather than on a precisely known value." ;
  rdfs:subClassOf obo:OBI_0000673 .

obo:OBCS_0000237 a rdf:Property ;
  rdfs:label "test follows probability distribution"@en ;
  rdfs:comment "An object property that represents a relation between a statistical test and a probability distribution." ;
  rdfs:range <https://w3id.org/linkml/Any> .

obo:OBI_0002748 a rdfs:Class ;
  rdfs:label "passage history record"@en ;
  rdfs:comment "A data item that is about the sequence of environmental systems in each of which is grown an organism in a passage process."@en ;
  rdfs:subClassOf obo:IAO_0000027 .

obo:OBCS_0000099 a rdfs:Class ;
  rdfs:label "lack of fit error" ;
  rdfs:comment "A statistical error that occurs when the analysis omits one or more important terms or factors from the model." ;
  rdfs:subClassOf obo:OBCS_0000082 .

obo:OBI_0003367 a rdfs:Class ;
  rdfs:label "diagnosis of an organism"@en ;
  rdfs:comment "A conclusion based on data about that an organism has a disease, disorder, or syndrome of a certain type, or none of these." ;
  rdfs:subClassOf obo:OBI_0001909 .

obo:OBI_0000124 a rdf:Property ;
  rdfs:label "is_supported_by_data" ;
  rdfs:comment "The relation between a data item and a conclusion where the conclusion is the output of a data interpreting process and the data item is used as an input to that process" ;
  rdfs:range <https://w3id.org/linkml/Any> .

obo:OBCS_0000291 a rdfs:Class ;
  rdfs:label "sporadic funding" ;
  rdfs:comment "definition to be confirmed" ;
  rdfs:subClassOf obo:OBCS_0000272 .

obo:OBI_0003083 a rdfs:Class ;
  rdfs:label "specimen collection time post disease onset" ;
  rdfs:comment "A specimen collection time measurement datum that is the measure of a time when specimens are collected after the onset of disease in a host." ;
  rdfs:subClassOf obo:OBI_0001619 .

obo:OBCS_0000032 a rdfs:Class ;
  rdfs:label "levene's test" ;
  rdfs:comment "A data transformation that is specifically an inferential statistic to assess the equality of variances in different sample; tests the null hypothesis that the population variances are equal (called homogeneity of variance or homoscedasticity)." ;
  rdfs:subClassOf obo:OBI_0000673 .

obo:OBCS_0000285 a rdfs:Class ;
  rdfs:label "labile and spreading symptom and side effect" ;
  rdfs:comment "definition to be confirmed" ;
  rdfs:subClassOf obo:OBCS_0000272 .

obo:OBI_0000968 a rdfs:Class ;
  rdfs:label "device" ;
  rdfs:comment "A material entity that is designed to perform a function in a scientific investigation, but is not a reagent." ;
  rdfs:subClassOf obo:OBI_0000047 .

obo:OBCS_0000179 a rdfs:Class ;
  rdfs:label "random permutation"@en ;
  rdfs:comment "A permutation process that randomly orders a set of data items." ;
  rdfs:subClassOf obo:OBCS_0000176 .

obo:OBCS_0000252 a rdfs:Class ;
  rdfs:label "objective uncertainty" ;
  rdfs:comment "An uncertainty that inheres in an objective continuant." ;
  rdfs:subClassOf obo:OBCS_0000251 .

obo:STATO_0000142 a rdfs:Class ;
  rdfs:label "correlation coefficient"@en ;
  rdfs:comment "The correlation coefficient of two variables in a data sample is their covariance divided by the product of their individual standard deviations. It is a normalized measurement of how the two are linearly related."@en ;
  rdfs:subClassOf obo:OBI_0000071 .

obo:OBI_0200146 a rdfs:Class ;
  rdfs:label "subgraph modularity calculation"@en ;
  rdfs:comment "A network subgraph quality calculation in which an input data set of subgraph in-degree and out-degree qualities is used to calculate the ratio of indegree to outdegree as a measure of modularity."@en ;
  rdfs:subClassOf obo:OBI_0200137 .

obo:OBI_0001144 a rdfs:Class ;
  rdfs:label "binding constant"@en ;
  rdfs:comment "A quantitative binding datum that is expressed as a scalar number and a unit, which can be utilized in equations that model the binding process independent of the specific assay performed."@en ;
  rdfs:subClassOf obo:OBI_0003142 .

obo:OBI_0200028 a rdfs:Class ;
  rdfs:label "quantile transformation"@en ;
  rdfs:comment "A quantile transformation is a data transformation that takes as input a collection of data sets, where each can be thought as an n-dimensional (real) vector, and which transforms each data set so that the resulting output data sets have equal quantiles."@en ;
  rdfs:subClassOf obo:OBI_0200169 , obo:OBI_0200181 .

obo:OBI_0200150 a rdfs:Class ;
  rdfs:label "MA transformation" ;
  rdfs:comment "An MA transformation is a data transformation which takes as input a collection of data points (g_1, r_1), (g_2, r_2), ..., (g_n, r_n)  with the r_i and g_i positive real numbers, and whose output is the collection of data points (A_1, M_1), (A_2, M_2), ..., (A_n, M_n) where, for each i, A_i=(log(g_i)+log(r_i))/2 and M_i=log(r_i)-log(g_i). Here log denotes a logarithmic transformation." ;
  rdfs:subClassOf obo:OBI_0200169 .

obo:OBI_0002479 a rdfs:Class ;
  rdfs:label "sequence read length measurement datum"@en ;
  rdfs:comment "A measurement datum that is the result of the measurement of the number of bases in a DNA or RNA sequence."@en ;
  rdfs:subClassOf obo:IAO_0000109 .

obo:OBCS_0000332 a rdfs:Class ;
  rdfs:label "prognosis uncertainty" ;
  rdfs:comment "definition and classification to be confirmed" ;
  rdfs:subClassOf obo:OBCS_0000253 .

obo:OBI_0200001 a rdfs:Class ;
  rdfs:label "geometric mean calculation"@en ;
  rdfs:comment "A data transformation in which the mean is calculated by taking the nth root of the product of all of the observations in a data (n being the number of all observations)." ;
  rdfs:subClassOf obo:APOLLO_SV_00000796 , obo:OBI_0200181 .

obo:OBCS_0000343 a rdfs:Class ;
  rdfs:label "reducible ignorance" ;
  rdfs:comment "Reducible  ignorance may be resolved by conducting further research,  which implies that it might be possible to somehow achieve a  better understanding. " ;
  rdfs:subClassOf obo:OBCS_0000342 .

obo:OBCS_0000314 a rdfs:Class ;
  rdfs:label "measurement error" ;
  rdfs:comment "definition to be confirmed" ;
  rdfs:subClassOf obo:OBCS_0000272 .

obo:OBCS_0000053 a rdfs:Class ;
  rdfs:label "test validity"@en ;
  rdfs:comment "A validity that refers to the degree to which evidence and theory support the interpretations of test scores (as entailed by proposed uses of tests)." ;
  rdfs:subClassOf obo:OBCS_0000060 .

obo:OBCS_0000247 a rdfs:Class ;
  rdfs:label "McNemar's test"@en ;
  rdfs:comment "A chi square test that is used on paired nominal data. It is applied to 2 × 2 contingency tables with a dichotomous trait, with matched pairs of subjects, to determine whether the row and column marginal frequencies are equal (that is, whether there is \"marginal homogeneity\"). It is named after Quinn McNemar, who introduced it in 1947." ;
  rdfs:subClassOf obo:OBI_0200200 .

obo:OBI_0000453 a rdfs:Class ;
  rdfs:label "measure function"@en ;
  rdfs:comment "Measure function is a function that is borne by a processed material  and realized in a process in which information about some entity is expressed relative to some reference."@en ;
  rdfs:subClassOf obo:BFO_0000034 .

obo:OBCS_0000043 a rdfs:Class ;
  rdfs:label "intervening variable specification" ;
  rdfs:comment "A variable postulated to be a predictor of one or more dependent variables, and simultaneously predicted by one or more independent variables" ;
  rdfs:subClassOf obo:IAO_0000033 .

obo:BFO_0000038 a rdfs:Class ;
  rdfs:label "one-dimensional temporal region"@en ;
  rdfs:subClassOf obo:BFO_0000008 .

obo:OBI_0200169 a rdfs:Class ;
  rdfs:label "normalization data transformation"@en ;
  rdfs:comment "A normalization data transformation is a data transformation that has objective normalization."@en ;
  rdfs:subClassOf obo:APOLLO_SV_00000796 , obo:OBCS_0000188 .

obo:OBCS_0000015 a rdfs:Class ;
  rdfs:label "central tendency" ;
  rdfs:comment "A data item that represents a typical value of a set of values. This term relates to the way in which quantitative data tend to cluster around some value." ;
  rdfs:subClassOf obo:OBCS_0000219 , obo:OBI_0000649 .

obo:OBI_0003355 a rdfs:Class ;
  rdfs:label "image data set analysis" ;
  rdfs:comment "The process of deriving a data item from an image data set using computer algorithms. The produced data item can be an image data set, data measurement, or any other data item." ;
  rdfs:subClassOf obo:OBI_0200000 .

obo:OBCS_0000089 a rdfs:Class ;
  rdfs:label "randomization sampling design" ;
  rdfs:comment "A data sampling design that uses randomization for sample selection" ;
  rdfs:subClassOf obo:OBCS_0000062 .

obo:OBCS_0000271 a rdfs:Class ;
  rdfs:label "uncertainty elimination" ;
  rdfs:comment "to be confirmed" ;
  rdfs:subClassOf obo:BFO_0000015 .

obo:OBCS_0000155 a rdfs:Class ;
  rdfs:label "construct validity"@en ;
  rdfs:comment "A test validity that refers to the extent to which operationalizations of a construct (i.e., practical tests developed from a theory) do actually measure what the theory says they do. For example, to what extent is a questionnaire actually measuring \"intelligence\"?" ;
  rdfs:subClassOf obo:OBCS_0000053 .

obo:OBCS_0000325 a rdfs:Class ;
  rdfs:label "complexity-induced uncertainty" ;
  rdfs:comment "definition to be confirmed" ;
  rdfs:subClassOf obo:OBCS_0000253 .

obo:STATO_0000219 a rdfs:Class ;
  rdfs:label "RT-PCR standard curve"@en ;
  rdfs:comment "a real time pcr standard curve is a line graph which plots the fluorescence intensity signal as a function of the concentration of a sample used as reference  and used to determine relative abundance of test samples"@en ;
  rdfs:subClassOf obo:IAO_0000573 .

obo:OBI_0001352 a rdfs:Class ;
  rdfs:label "allele information"@en ;
  rdfs:comment "a genetic alteration information that about one of two or more alternative forms of a gene or marker sequence and differing from other alleles at one or more mutational sites based on sequence. Polymorphisms are included in this definition."@en ;
  rdfs:subClassOf obo:OBI_0001364 .

obo:BFO_0000050 a rdf:Property ;
  rdfs:label "part of"@en ;
  rdfs:comment "a core relation that holds between a part and its whole"@en ;
  rdfs:seeAlso <http://www.obofoundry.org/ro/#OBO_REL:part_of> ;
  rdfs:range <https://w3id.org/linkml/Any> .

obo:OBCS_0000274 a rdfs:Class ;
  rdfs:label "rarity of event" ;
  rdfs:comment "Rare or extreme events are events that occur with low frequency, and often refers to infrequent events that have a widespread effect and which might destabilize systems" ;
  rdfs:subClassOf obo:OBCS_0000272 .

obo:OBI_0001404 a rdfs:Class ;
  rdfs:label "genetic characteristics information"@en ;
  rdfs:comment "a data item that is about genetic material including polymorphisms, disease alleles, and haplotypes."@en ;
  rdfs:subClassOf obo:IAO_0000027 .

obo:OBI_0600036 a rdfs:Class ;
  rdfs:label "establishing cell culture" ;
  rdfs:comment "a process through which a new type of cell culture or cell line is created, either through the isolation and culture of one or more cells from a fresh source, or the deliberate experimental modification of an existing cell culture (e.g passaging a primary culture to become a secondary culture or line, or the immortalization or stable genetic modification of an existing culture or line)." ;
  rdfs:subClassOf obo:OBI_0000094 .

obo:OBCS_0000263 a rdfs:Class ;
  rdfs:label "error propagation equation" ;
  rdfs:comment "Equations aimed to assess how the quantified uncertainties in model  inputs propagate in model calculations to produce and uncertainty range in a given model  outcome of interest.In statistics, propagation of uncertainty (or propagation of error) is the effect of variables' uncertainties (or errors, more specifically random errors) on the uncertainty of a function based on them. When the variables are the values of experimental measurements they have uncertainties due to measurement limitations (e.g., instrument precision) which propagate due to the combination of variables in the function." ;
  rdfs:subClassOf obo:OBCS_0000258 .

obo:OBI_2000009 a rdfs:Class ;
  rdfs:label "bodily fluid specimen" ;
  rdfs:comment "A specimen that is derived from some bodily fluid" ;
  rdfs:subClassOf obo:OBI_0001479 .

obo:OBCS_0000348 a rdfs:Class ;
  rdfs:label "model structure uncertainty" ;
  rdfs:comment "uncertainty about the form of the model itself. Model structure uncertainty arises from a lack of sufficient understanding of the system (past, present, or future) that is the subject of the policy analysis, including the behaviour of the system and the interrelationships among its elements." ;
  rdfs:subClassOf obo:OBCS_0000347 .

obo:OBCS_0000056 a rdfs:Class ;
  rdfs:label "relative risk" ;
  rdfs:comment "A data item that equals the incidence in exposed individuals divided by the incidence in unexposed individuals. The relative risk can be calculated from studies in which the proportion of patients exposed and unexposed to a risk is known, such as a cohort study." ;
  rdfs:subClassOf obo:OBCS_0000220 .

obo:OBCS_0000337 a rdfs:Class ;
  rdfs:label "positive uncertainty" ;
  rdfs:comment "definition and classification to be confirmed" ;
  rdfs:subClassOf obo:OBCS_0000251 .

obo:OBI_0000951 a rdfs:Class ;
  rdfs:label "compound treatment design" ;
  rdfs:comment "an intervention design in which the treatment is the administration of a compound" ;
  rdfs:subClassOf obo:OBI_0000115 .

obo:OBI_0200094 a rdfs:Class ;
  rdfs:label "logarithmic transformation"@en ;
  rdfs:comment "A logarithmic transformation is a data transformation consisting in the application of the logarithm function with a given base a (where a>0 and a is not equal to 1) to a (one dimensional) positive real number input. The logarithm function with base a can be defined as the inverse of the exponential function with the same base. See e.g. http://en.wikipedia.org/wiki/Logarithm."@en ;
  rdfs:subClassOf obo:OBI_0200169 .

obo:OBI_0000684 a rdfs:Class ;
  rdfs:label "specimen collection objective" ;
  rdfs:comment "A objective specification to obtain a material entity for potential use as an input during an investigation." ;
  rdfs:subClassOf obo:IAO_0000005 .

obo:OBI_0500020 a rdfs:Class ;
  rdfs:label "time series design" ;
  rdfs:comment "Groups of assays that are related as part of a time series." ;
  rdfs:subClassOf obo:OBI_0500000 .

obo:OBI_0200124 a rdfs:Class ;
  rdfs:label "kurtosis calculation"@en ;
  rdfs:comment "A kurtosis calculation is a descriptive statistics calculation defined as a parameter that measures how large or small the tails of a distribution are relative to the mean.  For details, see http://davidmlane.com/hyperstat/A53638.html"@en ;
  rdfs:subClassOf obo:OBI_0200086 .

obo:OBCS_0000048 a rdfs:Class ;
  rdfs:label "absolute risk" ;
  rdfs:comment "A data item of an observed or calculated probability of occurrence of an event, X, in a population related to exposure to a specific hazard, infection, trauma; the number of persons suffering from a disease when the exposed population is known with certainty." ;
  rdfs:subClassOf obo:OBCS_0000220 .

obo:OBI_0200012 a rdfs:Class ;
  rdfs:label "loess scale group transformation two-channel"@en ;
  rdfs:comment "A loess scale group transformation two-channel is a loess scale group transformation consisting in the application of a scale adjustment following a loess group transformation two-channel, to render the M group variances similar."@en ;
  rdfs:subClassOf obo:OBI_0200025 .

obo:RO_0002087 a rdf:Property ;
  rdfs:label "immediately preceded by"@en ;
  rdfs:comment "X immediately_preceded_by Y iff: end(X) simultaneous_with start(Y)"@en ;
  rdfs:domain obo:BFO_0000003 ;
  rdfs:range obo:BFO_0000003 ;
  rdfs:subPropertyOf obo:BFO_0000062 .

obo:OBI_0003328 a rdfs:Class ;
  rdfs:label "magnetic resonance image data set" ;
  rdfs:comment "An image data set whose information content originates from some MR imaging assay and is about some MRI participant." ;
  rdfs:subClassOf obo:OBI_0003327 .

obo:PATO_0001241 a rdfs:Class ;
  rdfs:label "physical object quality" ;
  rdfs:comment "A quality which inheres in a continuant." ;
  rdfs:subClassOf obo:PATO_0000001 .

obo:OBCS_0000359 a rdfs:Class ;
  rdfs:label "institutional uncertainty" ;
  rdfs:comment "Institutional uncertainty is in some sense a subset of societal uncertainty, and refers more specifically to the role and actions of institutions and their members. Institutional uncertainty stems from the \"diverse cultures and traditions, divergent missions and values, different structures, and work styles among personnel of different agencies\" (De Marchi, 1994). High institutional uncertainty can hinder collaboration or understanding among agencies, and can make the actions of institutions difficult to predict." ;
  rdfs:subClassOf obo:OBCS_0000358 .

obo:OBI_0003142 a rdfs:Class ;
  rdfs:label "quantitative binding datum" ;
  rdfs:comment "A binding datum that is expressed using numbers." ;
  rdfs:subClassOf obo:OBI_0001181 .

obo:OBCS_0000225 a rdfs:Class ;
  rdfs:label "data set following normal distribution"@en ;
  rdfs:comment "A data set that follows a normal distribution"@en ;
  rdfs:subClassOf obo:OBCS_0000224 .

obo:OBI_0002395 a rdfs:Class ;
  rdfs:label "number of live births" ;
  rdfs:comment "A measurement datum of the total number of live births a female has had." ;
  rdfs:subClassOf obo:IAO_0000109 .

obo:OBCS_0000162 a rdfs:Class ;
  rdfs:label "representation validity"@en ;
  rdfs:comment "A content validity that refers to the extent to which an abstract theoretical construct can be turned into a specific practical test." ;
  rdfs:subClassOf obo:OBCS_0000158 .

obo:OBI_0200176 a rdfs:Class ;
  rdfs:label "Fisher's exact test" ;
  rdfs:comment "Fisher's exact test is a data transformation used to determine if there are nonrandom associations between two Fisher's exact test is a statistical significance test used in the analysis of contingency tables where sample sizes are small where the significance of the deviation from a null hypothesis can be calculated exactly, rather than relying on an approximation that becomes exact in the limit as the sample size grows to infinity, as with many statistical tests." ;
  rdfs:subClassOf obo:OBI_0000673 .

obo:OBCS_0000260 a rdfs:Class ;
  rdfs:label "local sensitivity analysis" ;
  rdfs:comment "Model evaluation performed by varying uncertain factors around specific reference values." ;
  rdfs:subClassOf obo:OBCS_0000259 .

obo:OBI_0002985 a rdfs:Class ;
  rdfs:label "magnetic resonance imaging assay" ;
  rdfs:comment "An imaging assay in which nuclear magnetic resonance is used to produce information about the interior structure and composition of an input material entity." ;
  rdfs:subClassOf obo:OBI_0000185 .

obo:OBCS_0000095 a rdfs:Class ;
  rdfs:label "disease test specificity" ;
  rdfs:comment "A specificity that refers to the number of patients who have a negative test and do not have the disease divided by the number of patients who do not have the disease. A test with high specificity will infrequently identify patients as having a disease when they do not (i.e., few false positive results)." ;
  rdfs:subClassOf obo:OBCS_0000059 .

obo:OBI_0003260 a rdfs:Class ;
  rdfs:label "umbilical cord blood microbiology datum" ;
  rdfs:comment "An organism detection datum that is the specified output of an umbilical cord blood microbiology assay." ;
  rdfs:subClassOf obo:OBI_0003064 , obo:OBI_0003244 , obo:OBI_0003259 .

obo:UBERON_0002097 a rdfs:Class ;
  rdfs:label "skin of body" ;
  rdfs:comment "The organ covering the body that consists of the dermis and epidermis." ;
  rdfs:subClassOf obo:PR_000050567 , obo:UBERON_0000062 , obo:UBERON_0004121 .

obo:OBCS_0000190 a rdfs:Class ;
  rdfs:label "square root transformation"@en ;
  rdfs:comment "A data transformation that performs an operation of square root."@en ;
  rdfs:subClassOf obo:OBCS_0000188 .

obo:OBCS_0000017 a rdfs:Class ;
  rdfs:label "cohen's kappa measurement" ;
  rdfs:comment "A statistical measure of agreement for categorical data; a measure of inter-rater agreement or inter-annotator agreement." ;
  rdfs:subClassOf obo:OBCS_0000109 .

obo:STATO_0000060 a rdfs:Class ;
  rdfs:label "hypergeometric distribution"@en ;
  rdfs:comment "hypergeometric distribution is a probability distribution that describes the probability of  k successes in n draws from a finite population of size  N containing  K successes without replacement"@en ;
  rdfs:subClassOf obo:OBCS_0000067 .

obo:OBCS_0000086 a rdfs:Class ;
  rdfs:label "logit regression" ;
  rdfs:comment "A type of regression analysis used for predicting the outcome of a categorical dependent variable" ;
  rdfs:subClassOf obo:OBI_0200102 .

obo:OBCS_0000037 a rdfs:Class ;
  rdfs:label "statistical effect" ;
  rdfs:comment "A directive information entity that shows how changing the settings of a factor changes the response. The effect of a single factor is also called a main effect." ;
  rdfs:subClassOf obo:IAO_0000033 .

obo:OBCS_0000289 a rdfs:Class ;
  rdfs:label "poor management-staff relation" ;
  rdfs:comment "definition to be confirmed" ;
  rdfs:subClassOf obo:OBCS_0000272 .

obo:OBI_0200161 a rdfs:Class ;
  rdfs:label "quantile number of false positives correction method"@en ;
  rdfs:comment "A quantile number of false positives correction method is a MTP that controls for the pth quantile of the distribution of the number of false positives out of the total number of tests performed'" ;
  rdfs:subClassOf obo:APOLLO_SV_00000796 , obo:OBI_0200089 .

obo:OBCS_0000075 a rdfs:Class ;
  rdfs:label "random error" ;
  rdfs:comment "A component of experimental error that occurs due to natural variation in the process." ;
  rdfs:subClassOf obo:OBI_0000071 .

obo:OBCS_0000214 a rdfs:Class ;
  rdfs:label "sensitivity disposition"@en ;
  rdfs:comment "A disposition that inheres in a population of continuant and is realized in a test process (e.g., disease diagnosis)." ;
  rdfs:subClassOf obo:BFO_0000016 .

obo:OBCS_0000294 a rdfs:Class ;
  rdfs:label "reacting subject" ;
  rdfs:comment "definition to be confirmed" ;
  rdfs:subClassOf obo:OBCS_0000272 .

obo:OBCS_0000231 a rdfs:Class ;
  rdfs:label "mortality rate"@en ;
  rdfs:comment "A rate of deaths (in general, or due to a specific cause) that in a particular population, scaled to the size of that population, per unit of time. " ;
  rdfs:subClassOf obo:PATO_0000161 .

obo:IAO_0000178 a rdfs:Class ;
  rdfs:label "material information bearer"@en ;
  rdfs:comment "A material entity in which a concretization of an information content entity inheres."@en ;
  rdfs:subClassOf obo:BFO_0000040 .

obo:OBCS_0000310 a rdfs:Class ;
  rdfs:label "standardization of techniques and material" ;
  rdfs:comment "definition to be confirmed" ;
  rdfs:subClassOf obo:OBCS_0000299 .

obo:OBI_0200017 a rdfs:Class ;
  rdfs:label "cosine transformation"@en ;
  rdfs:comment "A cosine transformation is a data transformation which consists in applying the cosine function to a (one dimensional) real number input. The cosine function is one of the basic trigonometric functions and a definition is provided, e.g., at http://mathworld.wolfram.com/Cosine.html."@en ;
  rdfs:subClassOf obo:OBI_0200169 .

obo:OBCS_0000028 a rdfs:Class ;
  rdfs:label "data collapsing" ;
  rdfs:comment "A data transformation that combines categories or ranges of values to produce a smaller number of categories" ;
  rdfs:subClassOf obo:OBI_0200000 .

<http://www.w3.org/2003/11/swrl#Variable> a rdfs:Class .

obo:BFO_0000141 a rdfs:Class ;
  rdfs:label "immaterial entity"@en ;
  rdfs:subClassOf obo:BFO_0000004 .

obo:UBERON_0001088 a rdfs:Class ;
  rdfs:label "urine" ;
  rdfs:comment "Excretion that is the output of a kidney." ;
  rdfs:subClassOf obo:UBERON_0000174 .

obo:STATO_0000120 a rdfs:Class ;
  rdfs:label "bean plot" ;
  rdfs:comment """beanplot is a plot in which (one or) multiple batches (\"beans\") are shown. Each bean consists of a density trace, which is mirrored to
form a polygon shape. Next to that, a one-dimensional scatter plot shows all the individual measurements, like in a stripchart.

The name beanplot stems from green beans. The density shape can be seen as the pod of a green bean, while the scatter plot shows the seeds inside the pod."""@en ;
  rdfs:subClassOf obo:IAO_0000038 .

obo:OBI_0000938 a rdfs:Class ;
  rdfs:label "categorical measurement datum" ;
  rdfs:comment "A measurement datum that is reported on a categorical scale." ;
  rdfs:subClassOf obo:IAO_0000109 .

obo:OBCS_0000151 a rdfs:Class ;
  rdfs:label "statistical conclusion validity"@en ;
  rdfs:comment "An experimental validity that refers to the degree to which conclusions about the relationship among variables based on the data are correct or ‘reasonable’." ;
  rdfs:subClassOf obo:OBCS_0000143 .

obo:OBCS_0000321 a rdfs:Class ;
  rdfs:label "societal variability" ;
  rdfs:comment "the chaotic and unpredictable nature of societal  processes (macro-level behaviour). The need to consider  societal and institutional processes as a major contributor  to uncertainty due to variability can be inferred from  various papers of Funtowicz, Ravetz, and de Marchi." ;
  rdfs:subClassOf obo:OBCS_0000272 .

obo:OBI_0200171 a rdfs:Class ;
  rdfs:label "partitioning data transformation"@en ;
  rdfs:comment "A partitioning data transformation is a data transformation that has objective partitioning."@en ;
  rdfs:subClassOf obo:OBI_0200000 .

obo:OBI_0003271 a rdfs:Class ;
  rdfs:label "bacteria in endotracheal tube aspirate datum" ;
  rdfs:comment "An endotracheal tube aspirate microbiology datum that is about bacteria." ;
  rdfs:subClassOf obo:OBI_0003255 .

obo:IAO_0000308 a rdfs:Class ;
  rdfs:label "figure"@en ;
  rdfs:comment "An information content entity consisting of a two dimensional arrangement of information content entities such that the arrangement itself is about something."@en ;
  rdfs:subClassOf obo:IAO_0000030 .

obo:BFO_0000011 a rdfs:Class ;
  rdfs:label "spatiotemporal region"@en ;
  rdfs:subClassOf obo:BFO_0000003 .

obo:OBI_0200135 a rdfs:Class ;
  rdfs:label "edge quality calculation"@en ;
  rdfs:comment "A network analysis in which an input data set describing node objects and edge relationships between node objects is used to determine the output quality of one of the edge relationships in the network."@en ;
  rdfs:subClassOf obo:OBI_0200080 .

obo:OBCS_0000176 a rdfs:Class ;
  rdfs:label "permutation"@en ;
  rdfs:comment "A data transformation process that re-arrange the order of all or part of a set of data items." ;
  rdfs:subClassOf obo:OBCS_0000188 .

obo:OBI_0000801 a rdfs:Class ;
  rdfs:label "spike train datum" ;
  rdfs:comment "A measurement datum which represents information about an ordered series of action potentials in an organism's CNS measured over time." ;
  rdfs:subClassOf obo:IAO_0000109 .

obo:OBCS_0000278 a rdfs:Class ;
  rdfs:label "instability of event (episodic, self-reversing, spreading)" ;
  rdfs:comment "definition to be confirmed" ;
  rdfs:subClassOf obo:OBCS_0000272 .

obo:OBI_0001157 a rdfs:Class ;
  rdfs:label "age since hatching measurement datum"@en ;
  rdfs:comment "An age measurement datum that is the result of the measurement of the age of an organism since hatching, the process of emergence from an egg." ;
  rdfs:subClassOf obo:OBI_0001167 .

obo:OBI_0001481 a rdfs:Class ;
  rdfs:label "lowess global transformation"@en ;
  rdfs:comment "A lowess transformation where the same normalization curve is used for all members of the data set; e.g. Features on an array, picked spots on a gel, or measured metabolites in a sample." ;
  rdfs:subClassOf obo:OBI_0001477 .

obo:OBCS_0000236 a rdfs:Class ;
  rdfs:label "non-parametric test"@en ;
  rdfs:comment "A statistical hypothesis test that is not based on any parameterized family of probability distributions." ;
  rdfs:subClassOf obo:OBI_0000673 .

obo:OBI_0200006 a rdfs:Class ;
  rdfs:label "biexponential transformation"@en ;
  rdfs:comment "A biexponential transformation is a data transformation that, for each (one dimensional) real number input x, outputs an approximation (found, e.g. with the Newton's method) to a solution y of the equation B(y)-x=0, where B denotes a b transformation."@en ;
  rdfs:subClassOf obo:OBI_0200072 , obo:OBI_0200169 .

obo:OBI_0200097 a rdfs:Class ;
  rdfs:label "non-negative matrix factorization"@en ;
  rdfs:comment "Non negative matrix factorization is a data transformation in which factorises a matrix and which forces that all elements must be equal to or greater than zero." ;
  rdfs:subClassOf obo:OBI_0200000 .

obo:OBCS_0000140 a rdfs:Class ;
  rdfs:label "robust multi-array average normalization"@en ;
  rdfs:comment "A normalization data transformation that used to create normalized gene expression level from microarray raw data. The raw intensity values are background corrected, log2 transformed and then quantile normalized in the RMA normalization process. " ;
  rdfs:subClassOf obo:OBI_0200169 .

obo:OBI_0001522 a rdfs:Class ;
  rdfs:label "sequence assembly algorithm"@en ;
  rdfs:comment "An algorithm used to assemble individual sequence reads into larger contiguous sequences (contigs).  Assembly details include but are not limited to assembler type (overlap-layout-consensus, deBruijn), assembler version, and any relevant quality control information such as per cent known genes/ESTs captured."@en ;
  rdfs:subClassOf obo:IAO_0000064 .

obo:OBI_0003272 a rdfs:Class ;
  rdfs:label "bacteria in lung datum" ;
  rdfs:comment "A lung microbiology datum that is about bacteria." ;
  rdfs:subClassOf obo:OBI_0003256 .

obo:OBI_0003581 a rdfs:Class ;
  rdfs:label "nasal aspirate microbiology datum" ;
  rdfs:comment "An organism detection datum that is the specified output of a nasal aspirate microbiology assay." ;
  rdfs:subClassOf obo:OBI_0003064 .

obo:OBI_0001305 a rdfs:Class ;
  rdfs:label "genotype information"@en ;
  rdfs:comment "a genetic characteristics information that is about the genetic material of an organism and minimally includes information about the genetic background and can in addition contain information about specific alleles, genetic modifications, etc."@en ;
  rdfs:subClassOf obo:OBI_0001404 .

obo:OBI_0002512 a rdfs:Class ;
  rdfs:label "bone marrow specimen" ;
  rdfs:comment "A specimen that is derived from bone marrow." ;
  rdfs:subClassOf obo:OBI_0001479 .

obo:PR_000050567 a rdfs:Class ;
  rdfs:label "protein-containing material entity" ;
  rdfs:comment "A material entity that minimally consists of a protein." ;
  rdfs:subClassOf obo:BFO_0000040 .

obo:OBCS_0000242 a rdfs:Class ;
  rdfs:label "Kolmogorov-Smirnov one sample test"@en ;
  rdfs:comment "A Kolmogorov-Smirnov test that compares a sample with a reference probability distribution." ;
  rdfs:subClassOf obo:OBCS_0000241 .

obo:STATO_0000201 a rdfs:Class ;
  rdfs:label "Spearman's rank correlation coefficient"@en ;
  rdfs:comment """Spearman's rank correlation coefficient is a correlation coefficient which is a nonparametric measure of statistical dependence between two ranked variables. It assesses how well the relationship between two variables can be described using a monotonic function. If there are no repeated data values, a perfect Spearman correlation of +1 or −1 occurs when each of the variables is a perfect monotone function of the other.
Spearman's coefficient may be used when the conditions for computing Pearson's correlation are not met (e.g linearity, normality of the 2 continuous variables) but may require a ranking transformation of the variables"""@en ;
  rdfs:subClassOf obo:STATO_0000142 .

obo:OBCS_0000026 a rdfs:Class ;
  rdfs:label "statistical association" ;
  rdfs:comment "An inferential statistical data analysis that analyze the relationship between two measured quantities that renders them statistically dependent" ;
  rdfs:subClassOf obo:OBCS_0000121 .

obo:OBI_0200034 a rdfs:Class ;
  rdfs:label "jackknifing method"@en ;
  rdfs:comment "Jacknifing is a re-sampling data transformation process used to estimate the precision of sampling statistics and is a resampling method" ;
  rdfs:subClassOf obo:OBI_0000792 .

obo:CL_0000010 a rdfs:Class ;
  rdfs:label "cultured cell" ;
  rdfs:comment "A cell in vitro that is or has been maintained or propagated as part of a cell culture." ;
  rdfs:subClassOf obo:CL_0000578 .

obo:SO_0001248 a rdfs:Class ;
  rdfs:label "assembly" ;
  rdfs:comment "A region of the genome of known length that is composed by ordering and aligning two or more different regions." ;
  rdfs:subClassOf obo:SO_0001410 .

obo:OBI_0002371 a rdfs:Class ;
  rdfs:label "diagnosis of cancer" ;
  rdfs:comment "A diagnosis that is an assertion that a patient who is the subject of a diagnostic process has cancer." ;
  rdfs:subClassOf obo:OGMS_0000073 .

obo:OBI_0002136 a rdfs:Class ;
  rdfs:label "RNA Integrity Number calculation"@en ;
  rdfs:comment "A data transformation using the RIN algorithm to generate a quality measure of RNA based on features from an electrophoretic trace." ;
  rdfs:subClassOf obo:OBI_0200000 .

obo:OBI_0003282 a rdfs:Class ;
  rdfs:label "lung microbiology assay" ;
  rdfs:comment "An organism detection assay that detects microorganisms in a lung specimen." ;
  rdfs:subClassOf obo:OBI_0003235 , obo:OBI_0003498 .

obo:OBI_0200023 a rdfs:Class ;
  rdfs:label "loess global transformation"@en ;
  rdfs:comment "A loess global transformation is a loess transformation where only one loess fitting is performed, utilizing one subset of (or possibly all of) the data points in the input so that there is only one resulting loess curve y=f(x) which is used for the transformation."@en ;
  rdfs:subClassOf obo:OBI_0200071 .

obo:IAO_8000007 a rdfs:Class ;
  rdfs:label "curation subset ontology module"@en ;
  rdfs:comment "A subset ontology that is intended as a whitelist for curators using the ontology. Such a subset will exclude classes that curators should not use for curation."@en ;
  rdfs:subClassOf obo:IAO_8000006 .

obo:OBCS_0000187 a rdfs:Class ;
  rdfs:label "sorting based on lexicorgraphic order"@en ;
  rdfs:comment "A sorting process that sorts a set of data items based on a lexicorgraphic order" ;
  rdfs:subClassOf obo:OBCS_0000185 .

obo:STATO_0000287 a rdfs:Class ;
  rdfs:label "two tailed test"@en ;
  rdfs:comment "a two tailed test is a statistical test which assess the null hypothesis of absence of difference assuming a symmetric (not skewed) underlying probability distribution by allocating half of the significance level selected to each of the direction of change which could explain a difference (for example, a difference can be an excess or a loss)."@en ;
  rdfs:subClassOf obo:OBI_0000673 .

obo:OBI_0200165 a rdfs:Class ;
  rdfs:label "quantile proportion of false positives correction method"@en ;
  rdfs:comment "A quantile proportion of false positives correction method is a multiple testing procedure that controls the pth quantile of the distribution of the proportion of false positives among the rejected hypothesis (false discovery rate)." ;
  rdfs:subClassOf obo:APOLLO_SV_00000796 , obo:OBI_0200089 .

obo:OBI_0200109 a rdfs:Class ;
  rdfs:label "b transformation"@en ;
  rdfs:comment "A b transformation is a data transformation obtained by applying the function B described in what follows to a (one dimensional) real number input. B(x)= a*exp(b*x)-c*exp(-d*x)+f, where exp denotes an exponential transformation and a, b, c, d, f are real constants with a, b, c, d positive with the objective of normalization."@en ;
  rdfs:subClassOf obo:OBI_0200169 .

obo:BFO_0000040 a rdfs:Class ;
  rdfs:label "material entity"@en ;
  rdfs:comment "An independent continuant that is spatially extended whose identity is independent of that of other entities and can be maintained through time."@en ;
  rdfs:subClassOf obo:BFO_0000004 .

obo:OBCS_0000375 a rdfs:Class ;
  rdfs:label "uncertainty quantification" ;
  rdfs:comment "Representation of model output uncertainty using probability distributions." ;
  rdfs:subClassOf obo:OBI_0000011 .

obo:OBI_0001168 a rdfs:Class ;
  rdfs:label "age since fertilization measurement datum"@en ;
  rdfs:comment "An age measurement datum that is the result of the measurement of the age of an organism since fertilization, the process of the union of gametes of opposite sexes during the process of sexual reproduction to form a zygote." ;
  rdfs:subClassOf obo:OBI_0001167 .

obo:OBI_0002569 a rdfs:Class ;
  rdfs:label "trimmed sequence data" ;
  rdfs:comment "The results of a data transformation of sequence data in which (e.g., low quality) read bases are removed, to achieve some specific objective." ;
  rdfs:subClassOf obo:OBCS_0000233 , obo:OBI_0000973 .

obo:OBI_0600043 a rdfs:Class ;
  rdfs:label "genetic transformation"@en ;
  rdfs:comment "the introduction. alteration or integration of genetic material into a cell or organism"@en ;
  rdfs:subClassOf obo:OBI_0000094 .

obo:OBCS_0000229 a rdfs:Class ;
  rdfs:label "data collection from document"@en ;
  rdfs:comment "A data collection process that results in a collection of data generated from document(s)." ;
  rdfs:subClassOf obo:OBCS_0000002 .

obo:OBI_0003262 a rdfs:Class ;
  rdfs:label "virus in blood datum" ;
  rdfs:comment "A blood microbiology datum that is about a virus." ;
  rdfs:subClassOf obo:OBI_0003244 .

obo:STATO_0000240 a rdfs:Class ;
  rdfs:label "Kendall's correlation coefficient"@en ;
  rdfs:comment "Kendall's correlation coefficient is a correlation coefficient between 2 ordinal variables (natively or following a ranking procedure) and may be used when the conditions for computing Pearson's correlation are not met (e.g linearity, normality of the 2 continuous variables)"@en ;
  rdfs:subClassOf obo:STATO_0000142 .

obo:OBI_0002649 a rdfs:Class ;
  rdfs:label "blood microbiology assay" ;
  rdfs:comment "An organism detection assay that detects microorganisms in a blood specimen." ;
  rdfs:subClassOf obo:OBI_0003040 , obo:OBI_0003498 .

obo:OBCS_0000001 a rdfs:Class ;
  rdfs:label "statistical data analysis"@en ;
  rdfs:comment "A data transformation that has input of mulitple data and report overall trend of the data." ;
  rdfs:subClassOf obo:OBI_0200000 .

obo:UBERON_0010000 a rdfs:Class ;
  rdfs:label "multicellular anatomical structure" ;
  rdfs:comment "An anatomical structure that has more than one cell as a part." ;
  rdfs:subClassOf obo:UBERON_0000061 .

obo:OBI_0200117 a rdfs:Class ;
  rdfs:label "mode calculation"@en ;
  rdfs:comment "A mode calculation is a descriptive statistics calculation in which the mode is calculated which is the most common value in a data set. It is most often used as a measure of center for discrete data."@en ;
  rdfs:subClassOf obo:APOLLO_SV_00000796 , obo:OBI_0200181 .

obo:OBI_0000070 a rdfs:Class ;
  rdfs:label "assay"@en ;
  rdfs:comment "A planned process that has the objective to produce information about a material entity (the evaluant) by examining it."@en ;
  rdfs:subClassOf obo:OBI_0000011 .

obo:OBI_0002566 a rdfs:Class ;
  rdfs:label "file merge" ;
  rdfs:comment "A data transformation in which data contained in 2 or more files are merged into a single file." ;
  rdfs:subClassOf obo:OBI_0200000 .

obo:OBCS_0000120 a rdfs:Class ;
  rdfs:label "data matrix" ;
  rdfs:comment "A data item that is more specifically a rectangular array of numbers, symbols, or expressions, arranged in rows and columns." ;
  rdfs:subClassOf obo:IAO_0000027 .

obo:OBI_0002981 a rdfs:Class ;
  rdfs:label "reference gene sequence start site" ;
  rdfs:comment "The position of the first nucleotide in a reference gene sequence (sequence being used for comparison)." ;
  rdfs:subClassOf obo:OBI_0000973 .

obo:STATO_0000280 a rdfs:Class ;
  rdfs:label "Pearson's correlation coefficient"@en ;
  rdfs:comment """The Pearson's correlation coefficient is a correlation coefficient which evaluates two continuous variables for association strength in a data sample. It assumes that both variables are normally distributed and linearity exists. 
The coefficient is calculated by dividing their covariance with the product of their individual standard deviations. It is a normalized measurement of how the two are linearly related."""@en ;
  rdfs:subClassOf obo:STATO_0000142 .

obo:IAO_0000402 a rdfs:Class ;
  rdfs:label "two dimensional cartesian spatial coordinate datum"@en ;
  rdfs:comment "A cartesion spatial coordinate datum that  uses two values to specify a position within a two dimensional spatial region"@en ;
  rdfs:subClassOf obo:IAO_0000400 .

obo:SO_0000149 a rdfs:Class ;
  rdfs:label "contig" ;
  rdfs:comment "A contiguous sequence derived from sequence assembly. Has no gaps, but may contain N's from unavailable bases." ;
  rdfs:subClassOf obo:SO_0000353 .

obo:OBCS_0000132 a rdfs:Class ;
  rdfs:label "data collection by sampling"@en ;
  rdfs:comment "A data collection process that results in a collection of data from a sampling process." ;
  rdfs:subClassOf obo:OBCS_0000002 .

obo:OBCS_0000180 a rdfs:Class ;
  rdfs:label "factor analysis"@en ;
  rdfs:comment "A multivariate analysis that uncovers the latent structure (dimensions) of a set of variables. It reduces attribute space from a larger number of variables to a smaller number of factors." ;
  rdfs:subClassOf obo:OBCS_0000023 .

obo:OBI_0003295 a rdfs:Class ;
  rdfs:label "positive binding datum" ;
  rdfs:comment "A categorical binding datum that states that there is a significant disposition of two or more entities to form a complex." ;
  rdfs:subClassOf obo:OBI_0003141 .

obo:OBI_0000973 a rdfs:Class ;
  rdfs:label "sequence data"@en ;
  rdfs:comment "A measurement datum that representing the primary structure of a macromolecule(it's sequence) sometimes associated with an indicator of confidence of that measurement." ;
  rdfs:subClassOf obo:IAO_0000109 .

obo:OBI_0200020 a rdfs:Class ;
  rdfs:label "homogeneous polynomial transformation"@en ;
  rdfs:comment "A homogeneous polynomial transformation is a polynomial transformation where all the term of the polynomial have the same degree."@en ;
  rdfs:subClassOf obo:OBI_0200093 .

obo:STATO_0000048 a rdfs:Class ;
  rdfs:label "multiway ANOVA"@en ;
  rdfs:comment "Multi-way anova is an analysis of variance where the difference groups being compared are associated to the factor levels of more than 2 independent variables. The null hypothesis is an absence of difference between the means calculated for each of the groups. The test assumes normality and equivariance of the data."@en ;
  rdfs:subClassOf obo:OBI_0200201 .

obo:OBCS_0000218 a rdfs:Class ;
  rdfs:label "derived data from statistical analysis"@en ;
  rdfs:comment "A data item that is derived from a statistical data analysis." ;
  rdfs:subClassOf obo:IAO_0000027 , obo:OBCS_0000233 .

obo:OBCS_0000298 a rdfs:Class ;
  rdfs:label "order data sequentially or by spatial location" ;
  rdfs:comment "definition to be confirmed" ;
  rdfs:subClassOf obo:OBCS_0000273 .

obo:OBI_0200184 a rdfs:Class ;
  rdfs:label "descriptive statistical calculation data transformation"@en ;
  rdfs:comment "A descriptive statistical calculation data transformation is a data transformation that has objective descriptive statistical calculation and which concerns any calculation intended to describe a feature of a data set, for example, its center or its variability."@en ;
  rdfs:subClassOf obo:OBCS_0000001 .

obo:OBCS_0000303 a rdfs:Class ;
  rdfs:label "division of labor" ;
  rdfs:comment "definition to be confirmed" ;
  rdfs:subClassOf obo:OBCS_0000273 .

obo:OBI_0001506 a rdfs:Class ;
  rdfs:label "specimen with pre- or post-mortem status"@en ;
  rdfs:comment "A specimen that has been established to be taken from a live (pre-mortem) or dead (post-mortem) organism." ;
  rdfs:subClassOf obo:OBI_0100051 .

obo:OBI_0200080 a rdfs:Class ;
  rdfs:label "network analysis"@en ;
  rdfs:comment "A data transformation that takes as input data that describes biological networks in terms of the node (a.k.a. vertex) and edge graph elements and their characteristics and generates as output properties of the constituent nodes and edges, the sub-graphs, and the entire network."@en ;
  rdfs:subClassOf obo:OBI_0200000 .

obo:OBI_0003082 a rdfs:Class ;
  rdfs:label "extraction duration time" ;
  rdfs:comment "A time measurement datum that is the result of measuring the duration of an extraction process." ;
  rdfs:subClassOf obo:IAO_0000416 .

obo:OBI_0003498 a rdfs:Class ;
  rdfs:label "organism detection assay" ;
  rdfs:comment "An assay that detects a type of organism and/or the quantity of individuals of a type of organism." ;
  rdfs:subClassOf obo:OBI_0000070 .

obo:OBI_0000747 a rdfs:Class ;
  rdfs:label "material sample" ;
  rdfs:comment "A material entity that has the material sample role" ;
  rdfs:subClassOf obo:BFO_0000040 , obo:OBI_0100051 .

obo:OBI_0000356 a rdfs:Class ;
  rdfs:label "hypothesis generating investigation"@en ;
  rdfs:comment "is an investigation in which data is generated and analyzed with the purpose of generating new hypothesis"@en ;
  rdfs:subClassOf obo:OBI_0000066 .

obo:OBI_0003284 a rdfs:Class ;
  rdfs:label "umbilical cord blood microbiology assay" ;
  rdfs:comment "An organism detection assay that detects microorganisms in an umbilical cord blood specimen." ;
  rdfs:subClassOf obo:OBI_0002649 , obo:OBI_0003238 .

obo:IAO_0000100 a rdfs:Class ;
  rdfs:label "data set"@en ;
  rdfs:comment "A data item that is an aggregate of other data items of the same type that have something in common. Averages and distributions can be determined for data sets."@en ;
  rdfs:subClassOf obo:IAO_0000027 .

obo:OBI_0200106 a rdfs:Class ;
  rdfs:label "discriminant analysis"@en ;
  rdfs:comment "Discriminant function analysis is used to determine which variables discriminate between two or more naturally occurring groups. Analysis is used to determine which variable(s) are the best predictors of a particular outcome."@en ;
  rdfs:subClassOf obo:OBCS_0000121 .

obo:OBI_0003245 a rdfs:Class ;
  rdfs:label "feces assay datum" ;
  rdfs:comment "A data item that is the specified output of a feces assay." ;
  rdfs:subClassOf obo:IAO_0000027 .

obo:OBI_0003285 a rdfs:Class ;
  rdfs:label "nasopharyngeal or oropharyngeal swab microbiology assay" ;
  rdfs:comment "An organism detection assay that detects microorganisms in a nasopharyngeal or oropharyngeal swab specimen." ;
  rdfs:subClassOf obo:OBI_0003498 .

obo:OBCS_0000073 a rdfs:Class ;
  rdfs:label "percentile" ;
  rdfs:comment "A quantitative confidence value that equals the percentage of a distribution that is below a specific value. As an example, a child is in 90th percentile for weight if only 10 percent of children the same age weigh more than she does." ;
  rdfs:subClassOf obo:OBI_0000071 .

obo:BFO_0000023 a rdfs:Class ;
  rdfs:label "role"@en ;
  rdfs:comment "A realizable entity  the manifestation of which brings about some result or end that is not essential to a continuant  in virtue of the kind of thing that it is but that can be served or participated in by that kind of continuant  in some kinds of natural, social or institutional contexts."@en ;
  rdfs:subClassOf obo:BFO_0000017 .

obo:OBI_0003270 a rdfs:Class ;
  rdfs:label "virus in induced sputum datum" ;
  rdfs:comment "An induced sputum microbiology datum that is about a virus." ;
  rdfs:subClassOf obo:OBI_0003251 .

obo:OBI_0200054 a rdfs:Class ;
  rdfs:label "global modularity calculation"@en ;
  rdfs:comment "A network graph quality calculation in which an input data set of subgraph modules and their in-degree and out-degree qualities is used to calculate the average modularity of subgraphs within the network."@en ;
  rdfs:subClassOf obo:OBI_0200147 .

obo:STATO_0000262 a rdfs:Class ;
  rdfs:label "Bernoulli distribution"@en ;
  rdfs:comment """Bernoulli distribution is a binomial distribution where the number of trials is equal to 1.

notation: B(1,p)

The mean is p

The variance is p*q"""@en ;
  rdfs:subClassOf obo:OBCS_0000044 .

obo:OBI_0200031 a rdfs:Class ;
  rdfs:label "differential expression analysis objective"@en ;
  rdfs:comment "A differential expression analysis objective is a data transformation objective whose input consists of expression levels of entities (such as transcripts or proteins), or of sets of such expression levels, under two or more conditions and whose output reflects which of these are likely to have different expression across such conditions."@en ;
  rdfs:subClassOf obo:OBI_0200166 .

obo:CL_0000000 a rdfs:Class ;
  rdfs:label "cell" ;
  rdfs:comment "A material entity of anatomical origin (part of or deriving from an organism) that has as its parts a maximally connected cell compartment surrounded by a plasma membrane." ;
  rdfs:subClassOf obo:BFO_0000040 .

obo:OBI_0003592 a rdfs:Class ;
  rdfs:label "sequential organ failure assessment score"@en ;
  rdfs:comment "A clinical data item that quantifies the degree of function of a critically ill patient's organs." ;
  rdfs:subClassOf obo:OGMS_0000123 .

obo:OBCS_0000350 a rdfs:Class ;
  rdfs:label "input uncertainty" ;
  rdfs:comment "definition and classification to be confirmed" ;
  rdfs:subClassOf obo:OBCS_0000251 .

obo:OBI_0200079 a rdfs:Class ;
  rdfs:label "arithmetic mean calculation"@en ;
  rdfs:comment "An arithmetic mean calculation is a descriptive statistics calculation in which the mean is calculated by taking the sum of all of the observations in a data set divided by the total number of observations. It gives a measure of the 'center of gravity' for the data set. It is also known as the first moment."@en ;
  rdfs:subClassOf obo:APOLLO_SV_00000796 , obo:OBI_0200170 , obo:OBI_0200181 .

obo:OBI_0500011 a rdfs:Class ;
  rdfs:label "latin square design" ;
  rdfs:comment "Latin square design is_a study design which allows in its simpler form controlling 2 levels of nuisance variables (also known as blocking variables).he 2 nuisance factors are divided into a tabular grid with the property that each row and each column receive each treatment exactly once." ;
  rdfs:subClassOf obo:OBI_0500007 .

obo:OBCS_0000232 a rdfs:Class ;
  rdfs:label "hospital unit  shift rate"@en ;
  rdfs:comment "A rate of unit shif in a hospital. " ;
  rdfs:subClassOf obo:PATO_0000161 .

obo:IAO_0000309 a rdfs:Class ;
  rdfs:label "diagram"@en ;
  rdfs:comment "A figure that expresses one or more propositions"@en ;
  rdfs:subClassOf obo:IAO_0000308 .

obo:OBI_0200139 a rdfs:Class ;
  rdfs:label "quantitative subgraph degree calculation"@en ;
  rdfs:comment "A network subgraph quality calculation in which an input data set describing subgraphs and quantitative relationship edges between subgraphs and other network objects is used to sum the quantitative relationships of an individual subgraph."@en ;
  rdfs:subClassOf obo:OBI_0200137 .

obo:BFO_0000027 a rdfs:Class ;
  rdfs:label "object aggregate"@en ;
  rdfs:subClassOf obo:BFO_0000040 .

obo:OBCS_0000255 a rdfs:Class ;
  rdfs:label "objective process" ;
  rdfs:comment "A process in which tangible substances or objects undergo movement or change in a way that can be observed and measured independently, regardless of subjective interpretations or perceptions. It is a concept often used in scientific and objective contexts to describe the physical changes and movements of matter in the external world." ;
  rdfs:subClassOf obo:BFO_0000015 .

obo:OBI_0001621 a rdfs:Class ;
  rdfs:label "longitude coordinate measurement datum"@en ;
  rdfs:comment "A measurement datum that is the measure of the longitude coordinate of a site."@en ;
  rdfs:subClassOf obo:IAO_0000109 .

obo:OBCS_0000114 a rdfs:Class ;
  rdfs:label "median" ;
  rdfs:comment "A center value that separates the higher half from the lower half of the data sample, population, or probability distribution" ;
  rdfs:subClassOf obo:OBI_0000674 .

obo:OBI_0200027 a rdfs:Class ;
  rdfs:label "total intensity transformation paired"@en ;
  rdfs:comment "A total intensity transformation paired is a data transformation that takes as input two n-dimensional (real) vectors and multiplies each component of the first vector by a coefficient, where the coefficient is obtained by taking the ratio of the sum of the second input components or of a subset of these by the sum of the first input components or of a subset of these (the same subset is used for the two vectors)."@en ;
  rdfs:subClassOf obo:OBI_0200169 .

obo:IAO_8000002 a rdfs:Class ;
  rdfs:label "editors ontology module"@en ;
  rdfs:comment "An ontology module that is intended to be directly edited, typically managed in source control, and typically not intended for direct consumption by end-users."@en ;
  rdfs:subClassOf obo:IAO_8000000 .

obo:OBI_0001945 a rdfs:Class ;
  rdfs:label "scaffold N50"@en ;
  rdfs:comment "N50 statistic computed for the scaffold produced by the assembly process. The method for computing the value is similar to that of contig N50 but uses scaffold information instead of contig information" ;
  rdfs:subClassOf obo:OBI_0001940 .

obo:OBI_0002992 a rdfs:Class ;
  rdfs:label "prevalence of pathogen in specimens" ;
  rdfs:comment "A data item that is the frequency of detection of a specified pathogenic organism in collected specimens." ;
  rdfs:subClassOf obo:IAO_0000027 .

obo:OBI_0200043 a rdfs:Class ;
  rdfs:label "average linkage hierarchical clustering"@en ;
  rdfs:comment "An average linkage hierarchical clustering is an agglomerative hierarchical clustering which generates successive clusters based on a distance measure, where the distance between two clusters is calculated as the average distance between objects from the first cluster and objects from the second cluster."@en ;
  rdfs:subClassOf obo:OBI_0200154 .

obo:OBCS_0000374 a rdfs:Class ;
  rdfs:label "very low uncertainty level" ;
  rdfs:comment "definition to be confirmed" ;
  rdfs:subClassOf obo:OBCS_0000367 .

obo:OBCS_0000042 a rdfs:Class ;
  rdfs:label "dummy variable" ;
  rdfs:comment "A statistical variable with only two categories that reflect only part of the information available in a more comprehensive variable" ;
  rdfs:subClassOf obo:OBCS_0000038 .

obo:IAO_8000017 a rdfs:Class ;
  rdfs:label "ontology module subsetted by expressivity"@en ;
  rdfs:subClassOf obo:IAO_8000006 .

obo:OBI_0001566 a rdfs:Class ;
  rdfs:label "50% dissociation of binding temperature (Tm)" ;
  rdfs:comment "A quantitative binding datum that specifies the temperature at which half of the binding partners are forming a complex and the other half are unbound." ;
  rdfs:subClassOf obo:OBI_0003142 .

obo:OBI_0003374 a rdfs:Class ;
  rdfs:label "remote patient assessment"@en ;
  rdfs:comment "An organism diagnostic process which involves a remote assessment of a patient by a clinician."@en ;
  rdfs:subClassOf obo:OBI_0003366 .

obo:OBCS_0000088 a rdfs:Class ;
  rdfs:label "non-randomization sampling design" ;
  rdfs:comment "A data sampling design that does not use randomization for sample selection" ;
  rdfs:subClassOf obo:OBCS_0000062 .

obo:OBI_0002977 a rdfs:Class ;
  rdfs:label "input gene sequence start site" ;
  rdfs:comment "The position of the first nucleotide in a gene sequence being analyzed (input gene sequence)." ;
  rdfs:subClassOf obo:OBI_0000973 .

obo:OBCS_0000196 a rdfs:Class ;
  rdfs:label "ordinal data value"@en ;
  rdfs:comment "A data value that is an ordinal number, ie., a number that tells the position of something in a list." ;
  rdfs:subClassOf obo:OBCS_0000193 .

obo:OBI_0001164 a rdfs:Class ;
  rdfs:label "age since sowing measurement datum"@en ;
  rdfs:comment "An age measurement datum that is the result of the measurement of the age of an organism since sowing, the process of placing a seed or spore in some media with the intention to invoke germination." ;
  rdfs:subClassOf obo:OBI_0001167 .

obo:OBCS_0000093 a rdfs:Class ;
  rdfs:label "ratio scale" ;
  rdfs:comment "A measurement scale  that is similar to an interval scale, i.e. a magnitude of a continuous quantity and a unit magnitude of the same kind; the distinguishing feature of a ratio scale is a meaningful zero value that means the absence of whatever is measured." ;
  rdfs:subClassOf obo:OBCS_0000011 .

obo:IAO_0000572 a rdfs:Class ;
  rdfs:label "documenting"@en ;
  rdfs:comment "A planned process in which a document is created or added to by including the specified input in it."@en ;
  rdfs:subClassOf obo:OBI_0000011 .

obo:OBI_0200173 a rdfs:Class ;
  rdfs:label "background correction objective"@en ;
  rdfs:comment "A background correction objective is a data transformation objective where the aim is to remove irrelevant contributions from the measured signal, e.g. those due to instrument noise or sample preparation."@en ;
  rdfs:subClassOf obo:OBI_0200168 .

obo:OBI_0000658 a rdfs:Class ;
  rdfs:label "data representational model" ;
  rdfs:comment "Data representational model is an information content entity of the  relationships between data items. A data representational model is encoded in a data format specification such as for cytoscape or biopax." ;
  rdfs:subClassOf obo:IAO_0000033 .

obo:OBI_0003273 a rdfs:Class ;
  rdfs:label "eukaryota in lung datum" ;
  rdfs:comment "A lung microbiology datum that is about eukaryota." ;
  rdfs:subClassOf obo:OBI_0003256 .

obo:OBI_0200155 a rdfs:Class ;
  rdfs:label "divisive hierarchical clustering"@en ;
  rdfs:comment "A divisive hierarchical clustering is a hierarchical clustering which starts with a single cluster and then successively splits resulting clusters until only clusters of individual objects remain."@en ;
  rdfs:subClassOf obo:OBI_0200042 .

obo:OBCS_0000174 a rdfs:Class ;
  rdfs:label "collection of incommensurate data"@en ;
  rdfs:comment "A data collection process that deals with incommensurate fields in the data." ;
  rdfs:subClassOf obo:OBCS_0000002 .

obo:OBI_0000838 a rdfs:Class ;
  rdfs:label "material maintenance" ;
  rdfs:comment "A planned process with the objective to maintain some or all of the characteristics of an input material over time." ;
  rdfs:subClassOf obo:OBI_0000011 .

obo:OBCS_0000055 a rdfs:Class ;
  rdfs:label "prevalence rate" ;
  rdfs:comment "A data item that refers to the number of individuals with a given disease at a given point in time divided by the population at risk at a specified point in time or over a specified period of time." ;
  rdfs:subClassOf obo:OBCS_0000220 .

obo:GO_0006306 a rdfs:Class ;
  rdfs:label "DNA methylation" ;
  rdfs:comment "The covalent transfer of a methyl group to either N-6 of adenine or C-5 or N-4 of cytosine." ;
  rdfs:subClassOf obo:GO_0008150 .

obo:OBCS_0000102 a rdfs:Class ;
  rdfs:label "F test" ;
  rdfs:comment "A statistical hypothesis test in which the test statistic has an F-distribution under the null hypothesis" ;
  rdfs:subClassOf obo:OBI_0000673 .

obo:OBCS_0000020 a rdfs:Class ;
  rdfs:label "hierarchical linear model" ;
  rdfs:subClassOf obo:OBCS_0000035 .

obo:OBI_0003072 a rdfs:Class ;
  rdfs:label "axillary temperature measurement datum" ;
  rdfs:comment "A temperature measurement datum that is about an axilla." ;
  rdfs:subClassOf obo:OBI_0003079 .

obo:OBI_0002776 a rdfs:Class ;
  rdfs:label "cytometry analysis by automated gating" ;
  rdfs:comment "A gating in which the output of a flow- or mass- cytometry experiment is separated into gates that were set by an algorithm in order to quantify the frequency of different cell populations of interest." ;
  rdfs:subClassOf obo:OBI_0200077 .

obo:OBI_0001618 a rdfs:Class ;
  rdfs:label "average depth of sequence coverage"@en ;
  rdfs:comment "An average value of the depth of sequence coverage based both on external (e.g. Cot-based size estimates) and internal (average coverage in the assembly) measures of genome size."@en ;
  rdfs:subClassOf obo:OBI_0000679 .

obo:OBI_0002608 a rdfs:Class ;
  rdfs:label "oropharyngeal swab specimen" ;
  rdfs:comment "A specimen that is collected with a swab from the surface of a oropharynx." ;
  rdfs:subClassOf obo:OBI_0002599 .

obo:OBI_0200005 a rdfs:Class ;
  rdfs:label "feature extraction objective"@en ;
  rdfs:comment "A feature extraction objective is a data transformation objective where the aim of the data transformation is to generate quantified values from a scanned image."@en ;
  rdfs:subClassOf obo:OBI_0200166 .

obo:OBI_0000471 a rdfs:Class ;
  rdfs:label "study design execution" ;
  rdfs:comment "a planned process that carries out a study design" ;
  rdfs:subClassOf obo:OBI_0000011 .

obo:GO_0008150 a rdfs:Class ;
  rdfs:label "biological_process" ;
  rdfs:comment "A biological process is the execution of a genetically-encoded biological module or program. It consists of all the steps required to achieve the specific biological objective of the module. A biological process is accomplished by a particular set of molecular functions carried out by specific gene products (or macromolecular complexes), often in a highly regulated manner and in a particular temporal sequence." ;
  rdfs:subClassOf obo:BFO_0000015 .

obo:OBI_0000984 a rdfs:Class ;
  rdfs:label "dose" ;
  rdfs:comment "A measurement datum that measures the quantity of something that may be administered to an organism or that an organism may be exposed to. Quantities of nutrients, drugs, vaccines and toxins are referred to as doses." ;
  rdfs:subClassOf obo:IAO_0000109 .

obo:OBI_0001163 a rdfs:Class ;
  rdfs:label "age since eclosion measurement datum"@en ;
  rdfs:comment "An age measurement datum that is the result of the measurement of the age of an organism since eclosion, the process of emergence of an adult insect from its pupa or cocoon." ;
  rdfs:subClassOf obo:OBI_0001167 .

obo:OBI_0000662 a rdfs:Class ;
  rdfs:label "error corrected data set"@en ;
  rdfs:comment "A data set that is produced as the output of an error correction data transformation and consists of producing a data set which has had erroneous contributions from the input to the data transformation removed (corrected for)."@en ;
  rdfs:subClassOf obo:OBCS_0000123 .

obo:STATO_0000154 a rdfs:Class ;
  rdfs:label "violin plot" ;
  rdfs:comment """a violin plot is a plot combining the features of box plot and kernel density plot. The violin plot is therefore similar to box plot but it incorporated in the display the probability density of the data at different values.
Typically violin plots will include a marker for the median of the data and a box indicating the interquartile range, as in standard box plots."""@en ;
  rdfs:subClassOf obo:IAO_0000038 .

obo:PATO_0001422 a rdfs:Class ;
  rdfs:label "dead" ;
  rdfs:comment "A viability quality inhering in a bearer by virtue of the cessation of the bearer's life." ;
  rdfs:subClassOf obo:PATO_0000169 .

obo:OBCS_0000008 a rdfs:Class ;
  rdfs:label "log-normal distribution" ;
  rdfs:comment "A continuous probability that is the distribution of a random variable X if ln(X) is normally distributed" ;
  rdfs:subClassOf obo:OBCS_0000066 .

obo:OBI_0003251 a rdfs:Class ;
  rdfs:label "induced sputum microbiology datum" ;
  rdfs:comment "An organism detection datum that is the specified output of an induced sputum microbiology assay." ;
  rdfs:subClassOf obo:OBI_0003064 , obo:OBI_0003249 .

obo:OBCS_0000191 a rdfs:Class ;
  rdfs:label "Anscombe transformation"@en ;
  rdfs:comment "A variance-stabilizing transformation that transforms a random variable with a Poisson distribution into one with an approximately standard Gaussian distribution."@en ;
  rdfs:subClassOf obo:OBCS_0000188 .

obo:OBCS_0000239 a rdfs:Class ;
  rdfs:label "Friedman test"@en ;
  rdfs:comment "A special case of the Durbin test that was proposed by Milton Frieman and is applicable to complete block designs. Friedman test detects the differences in treatments across multiple test attempts. The procedure involves ranking each row (or block) together, then considering the values of ranks by columns." ;
  rdfs:subClassOf obo:OBCS_0000238 .

obo:OBI_0000131 a rdfs:Class ;
  rdfs:label "molecular feature identification objective"@en ;
  rdfs:comment "Molecular_feature_identification_objective is a biological_feature_identification_objective role describing a study designed to examine or characterize molecular features of a biological system, e.g. expression profiling, copy number of molecular components, epigenetic modifications."@en ;
  rdfs:subClassOf obo:OBI_0000015 .

obo:OBI_0200076 a rdfs:Class ;
  rdfs:label "column submatrix extraction"@en ;
  rdfs:comment "A column submatrix extraction is a submatrix extraction where all the rows of the input matrix are retained and selection only occurs on the columns."@en ;
  rdfs:subClassOf obo:OBI_0200074 .

obo:OBCS_0000002 a rdfs:Class ;
  rdfs:label "data collection"@en ;
  rdfs:comment "A planned process that gathers and measures information on variables of interest, in an established systematic fashion that enables one to answer stated research questions, test hypotheses, and evaluate outcomes. Data collection results in a collection of data." ;
  rdfs:subClassOf obo:OBI_0000011 .

obo:OBI_0000751 a rdfs:Class ;
  rdfs:label "study design dependent variable"@en ;
  rdfs:comment "dependent variable specification is part of a study design. The dependent variable is the event studied and expected to change when the independent variable varies."@en ;
  rdfs:subClassOf obo:IAO_0000033 .

obo:OBI_0200057 a rdfs:Class ;
  rdfs:label "replicate analysis"@en ;
  rdfs:comment "A replicate analysis is a data transformation in which data from replicates are combined, e.g. through descriptive statistics calculations, and the results might be utilized for a variety of purposes, like assessing reproducibility, identifying outliers, normalizing, etc."@en ;
  rdfs:subClassOf obo:OBI_0200169 .

obo:OBI_0600014 a rdfs:Class ;
  rdfs:label "material component separation"@en ;
  rdfs:comment "a material processing in which components of an input material become segregated in space"@en ;
  rdfs:subClassOf obo:OBI_0000094 .

obo:STATO_0000269 a rdfs:Class ;
  rdfs:label "polychoric correlation coefficient"@en ;
  rdfs:comment "polychoric correlation coefficient is a correlation coefficient which is computed over 2 variables to characterise an association by proxy with 2  (latent) variables which are assumed to be continuous and normally distributed."@en ;
  rdfs:subClassOf obo:STATO_0000142 .

obo:OBI_0000651 a rdfs:Class ;
  rdfs:label "urine specimen" ;
  rdfs:comment "a portion of urine collected from an organism" ;
  rdfs:subClassOf obo:OBI_0001479 .

obo:IAO_8000013 a rdfs:Class ;
  rdfs:label "reasoned ontology module"@en ;
  rdfs:comment "An ontology module that contains axioms generated by a reasoner. The generated axioms are typically direct SubClassOf axioms, but other possibilities are available."@en ;
  rdfs:seeAlso <http://robot.obolibrary.org/reason> ;
  rdfs:subClassOf obo:IAO_8000000 .

obo:OBCS_0000318 a rdfs:Class ;
  rdfs:label "subjective judgement" ;
  rdfs:comment "definition to be confirmed" ;
  rdfs:subClassOf obo:OBCS_0000272 .

obo:OBI_0002475 a rdfs:Class ;
  rdfs:label "number of PCR cycles during library construction"@en ;
  rdfs:comment "A data item that is the number of PCR cycles used during the construction of a sequencing library."@en ;
  rdfs:subClassOf obo:IAO_0000027 .

obo:UO_0000051 a rdfs:Class ;
  rdfs:label "concentration unit" ;
  rdfs:subClassOf obo:IAO_0000003 .

obo:IAO_0000180 a rdfs:Class ;
  rdfs:label "heatmap"@en ;
  rdfs:comment """A heatmap is a report graph which is a graphical representation of data
where the values taken by a variable(s) are shown as colors in a
two-dimensional map."""@en ;
  rdfs:subClassOf obo:IAO_0000038 .

obo:OBI_0001051 a rdfs:Class ;
  rdfs:label "DNA extract" ;
  rdfs:comment "The output of an extraction process in which DNA molecules are purified in order to exclude DNA from organellas." ;
  rdfs:subClassOf obo:OBI_0001010 .

obo:OBI_0000643 a rdf:Property ;
  rdfs:label "has grain" ;
  rdfs:comment "the relation of the cells in the finger of the skin to the finger, in which an indeterminate number of grains are parts of the whole by virtue of being grains in a collective that is part of the whole, and in which removing one granular part does not nec- essarily damage or diminish the whole. Ontological Whether there is a fixed, or nearly fixed number of parts - e.g. fingers of the hand, chambers of the heart, or wheels of a car - such that there can be a notion of a single one being missing, or whether, by contrast, the number of parts is indeterminate - e.g., cells in the skin of the hand, red cells in blood, or rubber molecules in the tread of the tire of the wheel of the car." ;
  rdfs:range <https://w3id.org/linkml/Any> , obo:CL_0000010 ;
  rdfs:subPropertyOf obo:BFO_0000051 .

obo:OBCS_0000307 a rdfs:Class ;
  rdfs:label "division of labor along technical/substantive line" ;
  rdfs:comment "definition to be confirmed" ;
  rdfs:subClassOf obo:OBCS_0000273 .

obo:BFO_0000016 a rdfs:Class ;
  rdfs:label "disposition"@en ;
  rdfs:subClassOf obo:BFO_0000017 .

obo:OBI_0003236 a rdfs:Class ;
  rdfs:label "milk assay" ;
  rdfs:comment "An assay that has a milk specimen as evaluant." ;
  rdfs:subClassOf obo:OBI_0000070 .

obo:OBCS_0000366 a rdfs:Class ;
  rdfs:label "uncertainty about value system" ;
  rdfs:comment "classification to be confirmed" ;
  rdfs:subClassOf obo:OBCS_0000363 .

obo:OBI_0001536 a rdfs:Class ;
  rdfs:label "equilibrium dissociation constant (KD)" ;
  rdfs:comment "A binding constant defined as the ratio of kon over koff (on-rate of binding divided by off-rate)" ;
  rdfs:subClassOf obo:OBI_0001144 .

obo:OBI_0000704 a rdfs:Class ;
  rdfs:label "decision tree induction objective" ;
  rdfs:comment "A decision tree induction objective is a data transformation objective in which a tree-like graph of edges and nodes is created and from which the selection of each branch requires that some type of logical decision is made." ;
  rdfs:subClassOf obo:OBI_0200166 .

obo:OBCS_0000066 a rdfs:Class ;
  rdfs:label "continuous probability distribution" ;
  rdfs:comment "A probability distribution that is associated with continuous variables and has a probability density function." ;
  rdfs:subClassOf obo:OBCS_0000010 .

obo:OBI_0002515 a rdfs:Class ;
  rdfs:label "pleural fluid specimen" ;
  rdfs:comment "A specimen that is derived from pleural fluid." ;
  rdfs:subClassOf obo:OBI_2000009 .

obo:OBI_0001588 a rdfs:Class ;
  rdfs:label "binding" ;
  rdfs:comment "The process of material entities forming complexes." ;
  rdfs:subClassOf obo:GO_0008150 .

obo:OBCS_0000165 a rdfs:Class ;
  rdfs:label "Patterns from Gene Expression software"@en ;
  rdfs:comment """A software that can be used to produce lists of differentially expressed genes with confidence measures attached. These lists are generated via a False Discovery Rate (FDR) method of controlling the false positives. Patterns from Gene Expression (PaGE) is more than a differential expression analysis tool.  PaGE is a tool to attach descriptive, dependable, and easily interpretable expression patterns to genes across multiple conditions, each represented by a set of replicated array experiments. 
""" ;
  rdfs:subClassOf obo:IAO_0000010 .

obo:OBI_0002534 a rdfs:Class ;
  rdfs:label "lung specimen" ;
  rdfs:comment "A specimen that is derived from lung." ;
  rdfs:subClassOf obo:OBI_0001479 .

obo:STATO_0000212 a rdfs:Class ;
  rdfs:label "tetrachoric correlation coefficient"@en ;
  rdfs:comment "a tetrachoric correlation coefficient is a polychoric correlation coefficient for 2 dichotomous variables used as proxy for correlation between 2 continuous latent variables."@en ;
  rdfs:subClassOf obo:STATO_0000269 .

obo:PATO_0001995 a rdfs:Class ;
  rdfs:label "organismal quality" ;
  rdfs:comment "A quality that inheres in an entire organism or part of an organism." ;
  rdfs:subClassOf obo:PATO_0001241 .

obo:OBCS_0000202 a rdfs:Class ;
  rdfs:label "interval-scale variable"@en ;
  rdfs:comment "A continuous variable that has order and equal intervals." ;
  rdfs:subClassOf obo:OBCS_0000200 .

obo:OBI_0003579 a rdfs:Class ;
  rdfs:label "bone marrow microbiology datum" ;
  rdfs:comment "An organism detection datum that is the specified output of a bone marrow microbiology assay." ;
  rdfs:subClassOf obo:OBI_0003064 .

obo:OBCS_0000292 a rdfs:Class ;
  rdfs:label "lack of institutional security" ;
  rdfs:comment "definition to be confirmed" ;
  rdfs:subClassOf obo:OBCS_0000272 .

obo:OBCS_0000361 a rdfs:Class ;
  rdfs:label "situational uncertainty" ;
  rdfs:comment "Situational uncertainty relates to \"the predicament of the person responsible for a crisis, either in the phase of preparation and planning, or of actual emergency. It refers to individual behaviours or personal interventions in crisis situations\" (De Marchi, 1994) and as such represents a form of integration over the other six types of uncertainty. That is, it tends to combine the uncertainties one has to face in a given situation or on a particular issue. High situational uncertainty would be characterized by situations where individual decisions play a substantial role and there is uncertainty about the nature of those decisions." ;
  rdfs:subClassOf obo:OBCS_0000251 .

obo:OBI_0200192 a rdfs:Class ;
  rdfs:label "classified data visualization" ;
  rdfs:comment "A data visualization which has input of a classified data set and produces an output of a report graph which is capable of rendering data of this type." ;
  rdfs:subClassOf obo:OBI_0200111 .

obo:OBCS_0000138 a rdfs:Class ;
  rdfs:label "diagnostic validity"@en ;
  rdfs:comment "A validity that refers to the validity of a diagnosis, and associated diagnostic tests or screening tests in a clinical field such as medicine." ;
  rdfs:subClassOf obo:OBCS_0000060 .

obo:OBCS_0000019 a rdfs:Class ;
  rdfs:label "correlation statistical analysis" ;
  rdfs:comment "A measure of the linear association between two variables that are measured on ordinal, interval or ratio scales" ;
  rdfs:subClassOf obo:OBCS_0000121 .

obo:OBI_0000673 a rdfs:Class ;
  rdfs:label "statistical hypothesis test"@en ;
  rdfs:comment "A statistical hypothesis test data transformation is a data transformation that has objective statistical hypothesis test."@en ;
  rdfs:subClassOf obo:OBCS_0000121 .

obo:OBCS_0000124 a rdfs:Class ;
  rdfs:label "inferential statistical data analysis objective"@en ;
  rdfs:comment "A statistical data analysis objective where the aim is to make inference using population sample data. " ;
  rdfs:subClassOf obo:OBI_0200166 .

obo:OBCS_0000282 a rdfs:Class ;
  rdfs:label "lack of causal model" ;
  rdfs:comment "definition to be confirmed" ;
  rdfs:subClassOf obo:OBCS_0000272 .

obo:IAO_0000030 a rdfs:Class ;
  rdfs:label "information content entity"@en ;
  rdfs:comment "A generically dependent continuant that is about some thing."@en ;
  rdfs:subClassOf obo:BFO_0000031 .

obo:OBCS_0000097 a rdfs:Class ;
  rdfs:label "interaction effect" ;
  rdfs:comment "A statistical effect that represents the role of a variable in an estimated model (most often a regression model) and its effect on the dependent variable. A variable that has an interaction effect will have a different effect on the dependent variable, depending on the level of some third variable." ;
  rdfs:subClassOf obo:OBCS_0000037 .

obo:OBI_0200089 a rdfs:Class ;
  rdfs:label "multiple testing correction method"@en ;
  rdfs:comment "A multiple testing correction method is a hypothesis test performed simultaneously on M > 1 hypotheses.  Multiple testing procedures produce a set of rejected hypotheses that is an estimate for the set of false null hypotheses while controlling for a suitably define Type I error rate" ;
  rdfs:subClassOf obo:OBCS_0000121 , obo:OBI_0000668 .

obo:OBCS_0000329 a rdfs:Class ;
  rdfs:label "diagnostic uncertainty" ;
  rdfs:comment "Diagnostic uncertainty arose when investigators attempted to fit a particular case into their taxonomies." ;
  rdfs:subClassOf obo:OBCS_0000253 .

obo:OBI_0001583 a rdfs:Class ;
  rdfs:label "half life of binding datum" ;
  rdfs:comment "A half life datum of the time it takes for 50% of bound complexes in an ensemble to disassociate in absence of re-association." ;
  rdfs:subClassOf obo:OBI_0001144 , obo:OBI_0001171 .

obo:OBI_0003240 a rdfs:Class ;
  rdfs:label "cerebrospinal fluid microbiology assay" ;
  rdfs:comment "An organism detection assay that detects microorganisms in a cerebrospinal fluid specimen." ;
  rdfs:subClassOf obo:OBI_0003232 , obo:OBI_0003498 .

obo:UBERON_0000064 a rdfs:Class ;
  rdfs:label "organ part" ;
  rdfs:comment "A multicellular structure that is a part of an organ." ;
  rdfs:subClassOf obo:UBERON_0010000 .

obo:OBCS_0000113 a rdfs:Class ;
  rdfs:label "weighted kappa" ;
  rdfs:comment "A weighted data that measures the agreement for categorical data; a generalization of the Kappa statistics to situations in which the categories are not equal in some respect so weighted by an objective or subjective function" ;
  rdfs:subClassOf obo:OBCS_0000014 .

obo:OBI_0000740 a rdfs:Class ;
  rdfs:label "material sample role" ;
  rdfs:comment "A material sample role is a specimen role borne by a material entity that is the output of a material sampling process." ;
  rdfs:subClassOf obo:OBI_0000112 .

obo:PATO_0000122 a rdfs:Class ;
  rdfs:label "length" ;
  rdfs:comment "A 1-D extent quality which is equal to the distance between two points." ;
  rdfs:subClassOf obo:PATO_0001241 .

obo:OBI_0001912 a rdfs:Class ;
  rdfs:label "cell freezing medium"@en ;
  rdfs:comment "A processed material that serves as a liquid vehicle for freezing cells for long term quiescent stroage, which contains chemicls needed to sustain cell viability across freeze-thaw cycles." ;
  rdfs:subClassOf obo:OBI_0000047 .

obo:STATO_0000165 a rdfs:Class ;
  rdfs:label "pie chart"@en ;
  rdfs:comment "a pie chart is a graph in which a circular graph is divided into sector illustrating numerical proportion, meaning that the arc length of each sector (and consequently its central angle and area), is proportional to the quantity it represents."@en ;
  rdfs:subClassOf obo:IAO_0000038 .

obo:OBI_0002471 a rdfs:Class ;
  rdfs:label "date process started"@en ;
  rdfs:comment "A data item that is the date when a process was initiated."@en ;
  rdfs:subClassOf obo:IAO_0000027 .

obo:OBI_0002508 a rdfs:Class ;
  rdfs:label "sputum specimen" ;
  rdfs:comment "A specimen that is derived from sputum." ;
  rdfs:subClassOf obo:OBI_0001479 .

obo:OBCS_0000077 a rdfs:Class ;
  rdfs:label "standard deviation" ;
  rdfs:comment "A quantitative confidence value that measures the variability of data around the mean." ;
  rdfs:subClassOf obo:OBI_0000071 .

obo:OBCS_0000149 a rdfs:Class ;
  rdfs:label "data collection from observation"@en ;
  rdfs:comment "A data collection process that results in a collection of data generated from observation(s)." ;
  rdfs:subClassOf obo:OBCS_0000002 .

obo:IAO_8000006 a rdfs:Class ;
  rdfs:label "subset ontology module"@en ;
  rdfs:comment "An ontology module that is extracted from a main ontology module and includes only a subset of entities or axioms."@en ;
  rdfs:seeAlso <http://robot.obolibrary.org/filter> , <http://www.geneontology.org/page/go-slim-and-subset-guide> ;
  rdfs:subClassOf obo:IAO_8000000 .

obo:STATO_0000128 a rdfs:Class ;
  rdfs:label "Altman box and whisker plot" ;
  rdfs:comment "Altman Box and Whisker plot is a variation of Tukey Box and Whisker plot which use the criteria of Altman to create the 'whisker' of the plot."@en ;
  rdfs:subClassOf obo:STATO_0000243 .

obo:OBCS_0000105 a rdfs:Class ;
  rdfs:label "case-control study design" ;
  rdfs:comment "A study design that starts with the outcome of interest and works backward to the exposure. For instance, patients with a disease are identified and compared with controls for exposure to a risk factor." ;
  rdfs:subClassOf obo:OBI_0500000 .

obo:OBI_0000272 a rdfs:Class ;
  rdfs:label "protocol"@en ;
  rdfs:comment "A plan specification which has sufficient level of detail and quantitative information to communicate it between investigation agents, so that different investigation agents will reliably be able to independently reproduce the process."@en ;
  rdfs:subClassOf obo:IAO_0000104 .

obo:OBI_0000995 a rdfs:Class ;
  rdfs:label "administration of material to specimen" ;
  rdfs:comment "The directed combination of a material entity with a specimen." ;
  rdfs:subClassOf obo:OBI_0000274 .

obo:OBCS_0000154 a rdfs:Class ;
  rdfs:label "ecological validity"@en ;
  rdfs:comment "An external validity that refers to the extent to which research results can be applied to real life situations outside of research settings." ;
  rdfs:subClassOf obo:OBCS_0000153 .

obo:OBI_0002583 a rdfs:Class ;
  rdfs:label "DNA methylation profiling data" ;
  rdfs:comment "The results of a DNA methylation profiling assay" ;
  rdfs:subClassOf obo:OBI_0000973 .

obo:OBI_0200101 a rdfs:Class ;
  rdfs:label "linear discriminant functional analysis"@en ;
  rdfs:comment "Linear discriminant functional analysis (LDFA) is a multivariate technique used in special applications where there are several intact groups (random assignment may be impossible) and they have been measured on several independent measures. Thus, you will want to describe how these groups differ on the basis of these measures. In this case, classification and prediction is the main objective."@en ;
  rdfs:subClassOf obo:APOLLO_SV_00000796 , obo:OBI_0000663 , obo:OBI_0200106 , obo:OBI_0200175 .

obo:UBERON_0000477 a rdfs:Class ;
  rdfs:label "anatomical cluster" ;
  rdfs:comment "Anatomical group whose component anatomical structures lie in close proximity to each other." ;
  rdfs:subClassOf obo:UBERON_0000465 .

obo:OBI_0003332 a rdfs:Class ;
  rdfs:label "magnetic resonance pulse sequence protocol"@en ;
  rdfs:comment "The NMR/MRI machine protocol about the radiofrequency pulse sequence." ;
  rdfs:subClassOf obo:OBI_0000272 .

obo:OBCS_0000178 a rdfs:Class ;
  rdfs:label "processing incompatible data"@en ;
  rdfs:comment "A data transformation process that transforms incompatible data to compatible data." ;
  rdfs:subClassOf obo:OBI_0200000 .

obo:OBI_0002601 a rdfs:Class ;
  rdfs:label "demultiplexed sequence data" ;
  rdfs:comment "Sequence data in which an identifier subsequence has been used to categorize each reads by source." ;
  rdfs:subClassOf obo:OBI_0000973 .

obo:OBI_0200091 a rdfs:Class ;
  rdfs:label "inter-rater reliability objective"@en ;
  rdfs:comment "a data transformation objective of determining the concordance or agreement between human judges." ;
  rdfs:subClassOf obo:OBI_0200166 .

obo:OBCS_0000029 a rdfs:Class ;
  rdfs:label "covariation" ;
  rdfs:comment "A measure of the extent to which two variables are associated; the extent to which two random variables vary together" ;
  rdfs:subClassOf obo:OBCS_0000121 .

obo:IAO_0000584 a rdfs:Class ;
  rdfs:label "time sampled measurement data set"@en ;
  rdfs:comment "A data set that is an aggregate of data recording some measurement at a number of time points. The time series data set is an ordered list of pairs of time measurement data and the corresponding measurement data acquired at that time."@en ;
  rdfs:subClassOf obo:IAO_0000100 .

obo:OBI_0200195 a rdfs:Class ;
  rdfs:label "proportional hazards model estimation" ;
  rdfs:comment "Proportional hazards model is a data transformation model to estimate the effects of different covariates influencing the times-to-failure of a system." ;
  rdfs:subClassOf obo:OBCS_0000121 , obo:OBI_0200194 .

obo:OBI_0002197 a rdfs:Class ;
  rdfs:label "tissue section thickness"@en ;
  rdfs:comment "A length measurement datum that is the result of an assay measuring the thickness of a tissue section." ;
  rdfs:subClassOf obo:IAO_0000408 .

obo:OBI_0200013 a rdfs:Class ;
  rdfs:label "loess global transformation one-channel"@en ;
  rdfs:comment "A loess global transformation one-channel is a loess global transformation in the special case where the input is the result of an MA transformation applied to intensities from two related one-channel assays."@en ;
  rdfs:subClassOf obo:OBI_0200023 .

obo:OBI_0001968 a rdfs:Class ;
  rdfs:label "operational taxonomic unit matrix"@en ;
  rdfs:comment "Operational Taxonomic Unit matrix  is a data item, organized as a table, where organismal taxonomic units, computed by sequence analysis and genetic distance calculation, are counted in a set of biological or environmental samples. The table is  used to appraise biodiversity of a population or community of living organism."@en ;
  rdfs:subClassOf obo:OBCS_0000233 .

obo:OBCS_0000210 a rdfs:Class ;
  rdfs:label "histogram distribution"@en ;
  rdfs:comment "A probability distribution that represents the probability distribution corresponding to a histogram of data values." ;
  rdfs:subClassOf obo:OBCS_0000010 .

obo:OBCS_0000322 a rdfs:Class ;
  rdfs:label "technological surprise" ;
  rdfs:comment "New developments or breakthroughs in technology or unexpected consequences (‘side-effects’) of technologies." ;
  rdfs:subClassOf obo:OBCS_0000272 .

obo:OBCS_0000050 a rdfs:Class ;
  rdfs:label "censored data" ;
  rdfs:comment "A data item collected from censoring that the value of a measurement or observation is only partially known." ;
  rdfs:subClassOf obo:IAO_0000027 .

obo:OBCS_0000373 a rdfs:Class ;
  rdfs:label "low uncertainty level" ;
  rdfs:comment "definition to be confirmed" ;
  rdfs:subClassOf obo:OBCS_0000367 .

obo:OBI_0000054 a rdfs:Class ;
  rdfs:label "ratio of collected to emitted light"@en ;
  rdfs:comment "A measurement datum measuring the amount of light collected s compared to the total amount of emitted light in the detector component of a flow cytometer instrument. The datum has a qualitative role"@en ;
  rdfs:subClassOf obo:IAO_0000109 .

obo:OBI_0000338 a rdfs:Class ;
  rdfs:label "drawing a conclusion based on data"@en ;
  rdfs:comment "A planned process in which data gathered in an investigation is evaluated in the context of existing knowledge with the objective to generate more general conclusions or to conclude that the data does not allow one to draw general conclusion"@en ;
  rdfs:subClassOf obo:OBI_0000011 .

obo:OBCS_0000355 a rdfs:Class ;
  rdfs:label "scientific uncertainty" ;
  rdfs:comment "Scientific uncertainty refers to uncertainty which emanates from the scientific and technical dimensions of a problem as opposed to the legal, moral, societal, institutional, proprietary, and situational dimensions outlined by De Marchi et al. Scientific uncertainty is intrinsic to the processes of risk assessment and forecasting." ;
  rdfs:subClassOf obo:OBCS_0000251 .

obo:IAO_0000414 a rdfs:Class ;
  rdfs:label "mass measurement datum"@en ;
  rdfs:comment "A scalar measurement datum that is the result of measurement of mass quality"@en ;
  rdfs:subClassOf obo:IAO_0000032 .

obo:OBI_0000666 a rdfs:Class ;
  rdfs:label "background correction data transformation"@en ;
  rdfs:comment "A background correction data transformation (sometimes called supervised classification) is a data transformation that has the objective background correction."@en ;
  rdfs:subClassOf obo:APOLLO_SV_00000796 , obo:OBCS_0000188 .

obo:OBI_0200016 a rdfs:Class ;
  rdfs:label "sine transformation"@en ;
  rdfs:comment "A sine transformation is a data transformation which consists in applying the sine function to a (one dimensional) real number input. The sine function is one of the basic trigonometric functions and a definition is provided, e.g., at http://mathworld.wolfram.com/Sine.html."@en ;
  rdfs:subClassOf obo:OBI_0200169 .

obo:OBI_0200049 a rdfs:Class ;
  rdfs:label "Benjamini and Yekutieli false discovery rate correction method"@en ;
  rdfs:comment "A data transformation in which the Benjamini and Yekutieli method is applied with the aim of correcting false discovery rate" ;
  rdfs:subClassOf obo:OBI_0200163 .

obo:BFO_0000001 a rdfs:Class ;
  rdfs:label "entity"@en .

obo:BFO_0000026 a rdfs:Class ;
  rdfs:label "one-dimensional spatial region"@en ;
  rdfs:subClassOf obo:BFO_0000006 .

obo:OBCS_0000288 a rdfs:Class ;
  rdfs:label "unequal status between investigators" ;
  rdfs:comment "definition to be confirmed" ;
  rdfs:subClassOf obo:OBCS_0000272 .

obo:OBI_0200132 a rdfs:Class ;
  rdfs:label "node in-degree calculation"@en ;
  rdfs:comment "A node quality calculation in which an input data set describing object nodes and directional relationship edges between object nodes is used to enumerate the number of unique relationships pointing into an individual object node."@en ;
  rdfs:subClassOf obo:OBI_0200129 .

obo:OBI_0002444 a rdfs:Class ;
  rdfs:label "measurand role"@en ;
  rdfs:comment "A role borne by a material entity and realized in an assay which achieves the objective to measure the magnitude/concentration/amount of the measurand in the entity bearing evaluant role." ;
  rdfs:subClassOf obo:BFO_0000023 .

obo:RO_0000081 a rdf:Property ;
  rdfs:label "role of"@en ;
  rdfs:comment "a relation between a role and an independent continuant (the bearer), in which the role specifically depends on the bearer for its existence"@en ;
  rdfs:range <https://w3id.org/linkml/Any> ;
  rdfs:subPropertyOf obo:RO_0000052 .

obo:OBI_0000125 a rdfs:Class ;
  rdfs:label "number of lost events electronic"@en ;
  rdfs:comment "A measurement datum measuring the number of analysis events lost due to errors in data acquisition electronic coincidence in a flow cytometer instrument. The datum has a qualitative role."@en ;
  rdfs:subClassOf obo:IAO_0000109 .

obo:OBI_0003077 a rdfs:Class ;
  rdfs:label "entomological data item" ;
  rdfs:comment "A data item that is about a collection of insects." ;
  rdfs:subClassOf obo:IAO_0000027 .

obo:IAO_0000592 a rdfs:Class ;
  rdfs:label "software module"@en ;
  rdfs:comment "A software module is software composed of a collection of software methods."@en ;
  rdfs:subClassOf obo:IAO_0000010 .

obo:OBCS_0000277 a rdfs:Class ;
  rdfs:label "material difficult to obtain" ;
  rdfs:comment "definition to be confirmed" ;
  rdfs:subClassOf obo:OBCS_0000272 .

obo:IAO_0000184 a rdfs:Class ;
  rdfs:label "scatter plot"@en ;
  rdfs:comment "A scatterplot is a graph which uses Cartesian coordinates to display values for two variables for a set of data. The data is displayed as a collection of points, each having the value of one variable determining the position on the horizontal axis and the value of the other variable determining the position on the vertical axis."@en ;
  rdfs:subClassOf obo:IAO_0000038 .

obo:OBI_0200085 a rdfs:Class ;
  rdfs:label "mass spectrometry analysis"@en ;
  rdfs:comment "A data transformation which has the objective of spectrum analysis." ;
  rdfs:subClassOf obo:OBI_0200000 .

obo:OBI_0003141 a rdfs:Class ;
  rdfs:label "categorical binding datum" ;
  rdfs:comment "A binding datum that is expressed as a categorical value." ;
  rdfs:subClassOf obo:OBI_0001181 .

obo:OBI_0200121 a rdfs:Class ;
  rdfs:label "standard deviation calculation"@en ;
  rdfs:comment "A standard deviation calculation is a descriptive statistics calculation defined as the square root of the variance.  Also thought of as the average distance of each value to the mean."@en ;
  rdfs:subClassOf obo:OBI_0200086 .

obo:OBCS_0000300 a rdfs:Class ;
  rdfs:label "find exemplars-filter for clear-cut case" ;
  rdfs:comment "definition to be confirmed" ;
  rdfs:subClassOf obo:OBCS_0000273 .

obo:OBCS_0000313 a rdfs:Class ;
  rdfs:label "substitution of theoretical validity for technical consistency" ;
  rdfs:comment "definition to be confirmed" ;
  rdfs:subClassOf obo:OBCS_0000273 .

obo:OBI_0001909 a rdfs:Class ;
  rdfs:label "conclusion based on data" ;
  rdfs:comment "An information content entity that is inferred from data." ;
  rdfs:subClassOf obo:IAO_0000030 .

obo:OBI_0001442 a rdfs:Class ;
  rdfs:label "q-value" ;
  rdfs:comment """A quantitative confidence value that measures the minimum false discovery rate that is incurred when calling that test significant. 
To compute q-values, it is necessary to know the p-value produced by a test and possibly set a false discovery rate level."""@en ;
  rdfs:subClassOf obo:OBI_0000071 , obo:OBI_0000662 .

obo:OBCS_0000160 a rdfs:Class ;
  rdfs:label "concurrent validity"@en ;
  rdfs:comment "A criterion validity that refers to the degree to which the operationalization correlates with other measures of the same construct that are measured at the same time. When the measure is compared to another measure of the same type, they will be related (or correlated). In the selection test example, this would mean that the tests are administered to current employees and then correlated with their scores on performance reviews." ;
  rdfs:subClassOf obo:OBCS_0000159 .

obo:OBI_0003252 a rdfs:Class ;
  rdfs:label "cerebrospinal fluid assay datum" ;
  rdfs:comment "A data item that is the specified output of a cerebrospinal fluid assay." ;
  rdfs:subClassOf obo:IAO_0000027 .

obo:STATO_0000132 a rdfs:Class ;
  rdfs:label "Hotelling T2 distribution"@en ;
  rdfs:comment """Hotelling T squared distribution is a probability distribution used in multivariate hypothesis testing, which is a univariate distribution proportional to the F-distribution and arises importantly as the distribution of a set of statistics which are natural generalizations of the statistics underlying Student's t-distribution.
In particular, the distribution arises in multivariate statistics in undertaking tests of the differences between the (multivariate) means of different populations, where tests for univariate problems would make use of a t-test.
The distribution is named for Harold Hotelling, who developed it[1] as a generalization of Student's t-distribution.
This distribution is commonly used to describe the sample Mahalanobis distance between two populations."""@en ;
  rdfs:subClassOf obo:OBCS_0000010 .

obo:IAO_8000011 a rdfs:Class ;
  rdfs:label "external import ontology module"@en ;
  rdfs:comment "An imported ontology module that is derived from an external ontology. Derivation methods include the OWLAPI SLME approach."@en ;
  rdfs:subClassOf obo:IAO_8000005 .

obo:OBCS_0000061 a rdfs:Class ;
  rdfs:label "polynomial regression" ;
  rdfs:comment "A special case of multiple linear regression in which the relationship between the independent variable x and the dependent variable y is modeled as an nth order polynomial" ;
  rdfs:subClassOf obo:OBI_0200103 .

obo:OBCS_0000206 a rdfs:Class ;
  rdfs:label "discrete ordinal variable"@en ;
  rdfs:comment "A nominal variable, but its different states are ordered in a meaningful sequence" ;
  rdfs:subClassOf obo:OBCS_0000205 .

obo:OBI_0002978 a rdfs:Class ;
  rdfs:label "input gene sequence stop site" ;
  rdfs:comment "The position of the last nucelotide in a gene sequence being analyzed (input gene sequence)." ;
  rdfs:subClassOf obo:OBI_0000973 .

obo:IAO_0000007 a rdfs:Class ;
  rdfs:label "action specification"@en ;
  rdfs:comment "A directive information entity that describes an action the bearer will take."@en ;
  rdfs:subClassOf obo:IAO_0000033 .

obo:OBCS_0000117 a rdfs:Class ;
  rdfs:label "rank order" ;
  rdfs:comment "A data item that represents an arrangement according to a rank, i.e., the position of a particular case relative to other cases on a defined scale." ;
  rdfs:subClassOf obo:OBCS_0000220 .

obo:OBI_0200002 a rdfs:Class ;
  rdfs:label "logistic-log curve fitting"@en ;
  rdfs:comment "A logistic-log curve fitting is a curve fitting where a curve of the form y=d+((a-d)/(1+(x/c)^b)) is obtained, where a, b, c, and d are determined so to optimize its fit to the input data points (x_1, y_1), (x_2, y_2), ..., (x_n, y_n)."@en ;
  rdfs:subClassOf obo:OBI_0200072 .

obo:OBCS_0000018 a rdfs:Class ;
  rdfs:label "causal model" ;
  rdfs:comment "A statistical model that an abstract, quantitative model of the causal dependencies and other interrelationships among observed or hypothetical models; an ordered triple , where U is a set of exogenous variables whose values are determined by factors outside the model; V is a set of endogenous variables whose values are determined by factors within the model; and E is a set of structural equations that express the value of each endogenous variable as a function of the values of the other variables in U and V." ;
  rdfs:subClassOf obo:OBCS_0000035 .

obo:OBI_0001479 a rdfs:Class ;
  rdfs:label "specimen from organism"@en ;
  rdfs:comment "A specimen that derives from an anatomical part or substance arising from an organism. Examples of tissue specimen include tissue, organ, physiological system, blood, or body location (arm)." ;
  rdfs:subClassOf obo:OBI_0100051 .

obo:OBCS_0000262 a rdfs:Class ;
  rdfs:label "screening sensitivity analysis" ;
  rdfs:comment "to be confirmed" ;
  rdfs:subClassOf obo:OBCS_0000259 .

obo:BFO_0000004 a rdfs:Class ;
  rdfs:label "independent continuant"@en ;
  rdfs:comment "b is an independent continuant = Def. b is a continuant which is such that there is no c and no t such that b s-depends_on c at t. (axiom label in BFO2 Reference: [017-002])"@en ;
  rdfs:subClassOf obo:BFO_0000002 .

obo:IAO_0000573 a rdfs:Class ;
  rdfs:label "line graph"@en ;
  rdfs:comment """A line graph is a type of graph created by connecting a series of data
points together with a line."""@en ;
  rdfs:subClassOf obo:IAO_0000038 .

obo:BFO_0000146 a rdfs:Class ;
  rdfs:label "two-dimensional continuant fiat boundary"@en ;
  rdfs:subClassOf obo:BFO_0000140 .

obo:OBI_0003238 a rdfs:Class ;
  rdfs:label "umbilical cord blood assay" ;
  rdfs:comment "An assay that has an umbilical cord blood specimen as evaluant." ;
  rdfs:subClassOf obo:OBI_0000070 .

obo:OBI_0000423 a rdfs:Class ;
  rdfs:label "extract"@en ;
  rdfs:comment "an extract is a material entity which results from an extraction process"@en ;
  rdfs:subClassOf obo:OBI_0000047 .

obo:OBCS_0000324 a rdfs:Class ;
  rdfs:label "probability" ;
  rdfs:comment "definition and classification to be confirmed" ;
  rdfs:subClassOf obo:OBCS_0000251 .

obo:BFO_0000015 a rdfs:Class ;
  rdfs:label "process"@en ;
  rdfs:comment "p is a process = Def. p is an occurrent that has temporal proper parts and for some time t, p s-depends_on some material entity at t. (axiom label in BFO2 Reference: [083-003])"@en ;
  rdfs:subClassOf obo:BFO_0000003 .

obo:OBI_0302859 a rdfs:Class ;
  rdfs:label "genetically modified organism"@en ;
  rdfs:comment "an organism that is the output of a genetic transformation process"@en ;
  rdfs:subClassOf obo:OBI_0001151 .

obo:OBCS_0000109 a rdfs:Class ;
  rdfs:label "kappa statistic" ;
  rdfs:comment "A statistic test for several similar measures of agreement used with categorical data; typically used in assessing the degree to which two or more raters, examining the same data, agree on assigning data to categories" ;
  rdfs:subClassOf obo:OBCS_0000013 .

obo:STATO_0000066 a rdfs:Class ;
  rdfs:label "Cleveland dot plot" ;
  rdfs:comment "Cleveland dot plot is a dot plot which plots points that each belong to one of several categories. They are an alternative to bar charts or pie charts, and look somewhat like a horizontal bar chart where the bars are replaced by a dots at the values associated with each category. Compared to (vertical) bar charts and pie charts, Cleveland argues that dot plots allow more accurate interpretation of the graph by readers by making the labels easier to read, reducing non-data ink (or graph clutter) and supporting table look-up.which"@en ;
  rdfs:subClassOf obo:IAO_0000037 .

obo:OBCS_0000128 a rdfs:Class ;
  rdfs:label "data collection from experiment"@en ;
  rdfs:comment "A data collection process that results in a collection of data generated from an experiment(s)." ;
  rdfs:subClassOf obo:OBCS_0000002 .

obo:OBI_0200188 a rdfs:Class ;
  rdfs:label "cross validation objective"@en ;
  rdfs:comment "A cross validation objective is a data transformation objective in which the aim is to partition a sample of data into subsets such that the analysis is initially performed on a single subset, while the other subset(s) are retained for subsequent use in confirming and validating the initial analysis."@en ;
  rdfs:subClassOf obo:OBI_0200172 .

obo:OBCS_0000025 a rdfs:Class ;
  rdfs:label "univariate analysis" ;
  rdfs:comment "An inferential statistical data analysis that has only one independent variable" ;
  rdfs:subClassOf obo:OBCS_0000121 .

obo:OBCS_0000311 a rdfs:Class ;
  rdfs:label "standardization of observational technique (form) and protocol" ;
  rdfs:comment "definition to be confirmed" ;
  rdfs:subClassOf obo:OBCS_0000299 .

obo:OBI_0002482 a rdfs:Class ;
  rdfs:label "specimen harvest quantity"@en ;
  rdfs:comment "A scalar measurement datum that indicates the amount of specimen collected."@en ;
  rdfs:subClassOf obo:IAO_0000109 .

obo:OBI_0200177 a rdfs:Class ;
  rdfs:label "center calculation objective"@en ;
  rdfs:comment "A center calculation objective is a data transformation objective where the aim is to calculate the center of an input data set."@en ;
  rdfs:subClassOf obo:OBI_0200166 .

obo:OBI_0200166 a rdfs:Class ;
  rdfs:label "data transformation objective"@en ;
  rdfs:comment "An objective specification to transformation input data into output data"@en ;
  rdfs:subClassOf obo:IAO_0000005 .

obo:OBI_0003235 a rdfs:Class ;
  rdfs:label "lung assay" ;
  rdfs:comment "An assay that has a lung specimen as evaluant." ;
  rdfs:subClassOf obo:OBI_0000070 .

obo:STATO_0000171 a rdfs:Class ;
  rdfs:label "Spear box and whisker plot" ;
  rdfs:comment "Spear Box and Whisker plot is a variation of Tukey Box and Whisker plot which use the criteria of Spear to create the 'whisker' of the plot."@en ;
  rdfs:subClassOf obo:STATO_0000243 .

obo:OBI_0003259 a rdfs:Class ;
  rdfs:label "umbilical cord blood assay datum" ;
  rdfs:comment "A data item that is the specified output of an umbilical cord blood assay." ;
  rdfs:subClassOf obo:IAO_0000027 .

obo:BFO_0000009 a rdfs:Class ;
  rdfs:label "two-dimensional spatial region"@en ;
  rdfs:subClassOf obo:BFO_0000006 .

obo:OBCS_0000175 a rdfs:Class ;
  rdfs:label "web crawling software"@en ;
  rdfs:comment "A software that is used to browses the World Wide Web in a methodical, automated manner." ;
  rdfs:subClassOf obo:IAO_0000010 .

obo:OBCS_0000083 a rdfs:Class ;
  rdfs:label "expected value" ;
  rdfs:comment "A quantitative confidence value that represents theoretical average value of a statistic over an infinite number of samples from the same population;  the weights correspond to the probabilities in the case of a discrete random variable or densities in the case of a continuous random variable." ;
  rdfs:subClassOf obo:OBI_0000071 .

obo:OBI_0200024 a rdfs:Class ;
  rdfs:label "loess group transformation"@en ;
  rdfs:comment "A loess group transformation is a loess transformation where the input is partitioned into groups and for each group a loess fitting is performed, utilizing a subset of (or possibly all of) the data points in that group. Thus, a collection of loess curves y=f_i(x) is generated, one per group. Each (x, y) in the input is transformed into (x, y-f_i(x)), where f_i(x) is the curve corresponding to the group to which that data point belongs."@en ;
  rdfs:subClassOf obo:OBI_0200071 .

obo:OBI_0000079 a rdfs:Class ;
  rdfs:label "culture medium"@en ;
  rdfs:comment "a processed material that provides the needed nourishment for microorganisms or cells grown in vitro." ;
  rdfs:subClassOf obo:OBI_0000047 .

obo:OBI_0200021 a rdfs:Class ;
  rdfs:label "linlog transformation"@en ;
  rdfs:comment "A linlog transformation is a data transformation, described in PMID 16646782, whose input is a matrix [y_ik] and whose output is a matrix obtained by applying formula (9) of this paper, where values below an appropriately determined threshold (dependent on the row i) are transformed via a polynomial of degree 1, and values above this threshold are transformed via a logarithm."@en ;
  rdfs:subClassOf obo:OBI_0200169 .

obo:OBI_0000269 a rdfs:Class ;
  rdfs:label "number of lost events computer"@en ;
  rdfs:comment "A measurement datum recording the number of measurement events lost due to overloading of the analysis chip in a flow cytometer instrument. The datum has a qualitative role"@en ;
  rdfs:subClassOf obo:IAO_0000109 .

obo:OBCS_0000189 a rdfs:Class ;
  rdfs:label "log2 transformation"@en ;
  rdfs:comment "A logarithmic transformation that uses the base-2 logarithm."@en ;
  rdfs:subClassOf obo:OBI_0200094 .

obo:OBI_0000251 a rdfs:Class ;
  rdfs:label "cluster"@en ;
  rdfs:comment "A data set which is a subset of data that are a similar to each other in some way."@en ;
  rdfs:subClassOf obo:IAO_0000100 .

obo:OBI_0001460 a rdfs:Class ;
  rdfs:label "genetic modification design" ;
  rdfs:comment "A study design in which an organism(s) is studied that has had genetic material removed, rearranged, mutagenized or added, such as in a knock out." ;
  rdfs:subClassOf obo:OBI_0000115 .

obo:OBCS_0000347 a rdfs:Class ;
  rdfs:label "model uncertainty" ;
  rdfs:comment "Model uncertainty is associated with both the conceptual model (i.e., the variables and their relationships that are chosen to describe the system located within the boundaries and thus constituting the model complex) and the computer model." ;
  rdfs:subClassOf obo:OBCS_0000253 .

obo:OBCS_0000074 a rdfs:Class ;
  rdfs:label "power" ;
  rdfs:comment "A quantitative confidence value that refers to the ability of a study to detect a true difference. Negative findings may reflect that the study was underpowered to detect a difference." ;
  rdfs:subClassOf obo:OBI_0000071 .

obo:OBI_0003263 a rdfs:Class ;
  rdfs:label "eukaryota in blood datum" ;
  rdfs:comment "A blood microbiology datum that is about eukaryota." ;
  rdfs:subClassOf obo:OBI_0003244 .

obo:OBI_0003416 a rdfs:Class ;
  rdfs:label "mid-upper arm circumference datum" ;
  rdfs:comment "A length measurement datum that is the specified output of an assay measuring the length around an upper arm, taken midway along the upper arm." ;
  rdfs:subClassOf obo:IAO_0000408 .

obo:OBCS_0000284 a rdfs:Class ;
  rdfs:label "lack of information for comparison" ;
  rdfs:comment "definition to be confirmed" ;
  rdfs:subClassOf obo:OBCS_0000272 .

obo:OBCS_0000302 a rdfs:Class ;
  rdfs:label "substitution of taxonomy for diagnosis" ;
  rdfs:comment "definition to be confirmed" ;
  rdfs:subClassOf obo:OBCS_0000273 .

obo:OBI_0200143 a rdfs:Class ;
  rdfs:label "subgraph in-degree calculation"@en ;
  rdfs:comment "A network subgraph quality calculation in which an input data set describing subgraphs and directional relationship edges between subgraphs and other network objects is used to enumerate the number of unique relationships pointing into an individual subgraph."@en ;
  rdfs:subClassOf obo:OBI_0200137 .

obo:UBERON_0007779 a rdfs:Class ;
  rdfs:label "transudate" ;
  rdfs:comment "Any bodily fluid that has passed through a membrane such as the capillary wall, as a result of unbalanced hydrostatic and osmotic forces." ;
  rdfs:subClassOf obo:UBERON_0006314 .

obo:OBCS_0000094 a rdfs:Class ;
  rdfs:label "disease test sensitivity" ;
  rdfs:comment "A sensitivity that refers to the number of patients with a positive test who have a disease divided by all patients who have the disease. A test with high sensitivity will not miss many patients who have the disease (i.e., few false negative results)." ;
  rdfs:subClassOf obo:OBCS_0000058 .

obo:OBI_0003354 a rdfs:Class ;
  rdfs:label "raw magnetic resonance image data set" ;
  rdfs:comment "An image data set that is the direct output of an magnetic resonance imaging assay and whose values encode spatial frequencies produced by the NMR or MRI instrument." ;
  rdfs:subClassOf obo:OBI_0003328 , obo:OBI_0003331 .

obo:OBI_0200151 a rdfs:Class ;
  rdfs:label "exponential base"@en ;
  rdfs:comment "The exponential base is a feature of an exponential function which is defined in http://en.wikipedia.org/wiki/Exponential_function. Its value can be any positive real number (typically different from 1)." ;
  rdfs:subClassOf obo:OBI_0200140 .

obo:OBI_0000292 a rdf:Property ;
  rdfs:label "has_feature_value"@en ;
  rdfs:comment "has_feature_value datatype property is used to describe the feature values which the feature class can contain, for example has_base can have feature values of nonNegativeInteger values."@en ;
  rdfs:range <https://w3id.org/linkml/Any> .

obo:OBI_0002599 a rdfs:Class ;
  rdfs:label "swab specimen" ;
  rdfs:comment "A specimen that is stored on a swab as the output of a collecting specimen with swab process." ;
  rdfs:subClassOf obo:OBI_0100051 .

obo:STATO_0000044 a rdfs:Class ;
  rdfs:label "one-way ANOVA"@en ;
  rdfs:comment "one-way anova is an analysis of variance where the different groups being compared are associated with the factor levels of only one independent variable. The null hypothesis is an absence of difference between the means calculated for each of the groups. The test assumes normality and equivariance of the data."@en ;
  rdfs:subClassOf obo:OBI_0200201 .

obo:OBI_0003274 a rdfs:Class ;
  rdfs:label "virus in lung datum" ;
  rdfs:comment "A lung microbiology datum that is about a virus." ;
  rdfs:subClassOf obo:OBI_0003256 .

obo:OBI_0002567 a rdfs:Class ;
  rdfs:label "sequence alignment" ;
  rdfs:comment "A data transformation in which one or more sequences (reads) are positioned on a reference sequence template (often a reference set of genes), according to the genetic base-pairing paradigm." ;
  rdfs:subClassOf obo:OBI_0200187 .

obo:OBCS_0000344 a rdfs:Class ;
  rdfs:label "irreducible ignorance" ;
  rdfs:comment "Irreducible ignorance applies when neither research nor development can provide sufficient knowledge about the essential relationships. " ;
  rdfs:subClassOf obo:OBCS_0000342 .

obo:OBI_0200140 a rdfs:Class ;
  rdfs:label "mathematical feature"@en ;
  rdfs:comment "feature is a (parent_class) that describes a characteristic, trait or quality of a data transformation"@en ;
  rdfs:subClassOf obo:OBI_0200000 .

obo:OBI_0000118 a rdfs:Class ;
  rdfs:label "gene list"@en ;
  rdfs:comment "A data set of the names or identifiers of genes that are the outcome of an analysis or have been put together for the purpose of an analysis."@en ;
  rdfs:subClassOf obo:IAO_0000100 .

obo:UBERON_0012168 a rdfs:Class ;
  rdfs:label "umbilical cord blood" ;
  rdfs:comment "Blood that remains in the placenta and in the attached umbilical cord after childbirth[WP]." ;
  rdfs:subClassOf obo:UBERON_0013755 .

obo:BFO_0000028 a rdfs:Class ;
  rdfs:label "three-dimensional spatial region"@en ;
  rdfs:subClassOf obo:BFO_0000006 .

obo:OBI_0001930 a rdfs:Class ;
  rdfs:label "categorical value specification" ;
  rdfs:comment "A value specification that is specifies one category out of a fixed number of nominal categories" ;
  rdfs:subClassOf obo:OBI_0001933 .

obo:CHEBI_23367 a rdfs:Class ;
  rdfs:label "molecular entity" ;
  rdfs:comment "Any constitutionally or isotopically distinct atom, molecule, ion, ion pair, radical, radical ion, complex, conformer etc., identifiable as a separately distinguishable entity." ;
  rdfs:subClassOf obo:BFO_0000040 .

obo:OBI_0003281 a rdfs:Class ;
  rdfs:label "eukaryota in umbilical cord blood datum" ;
  rdfs:comment "An umbilical cord blood microbiology datum that is about eukaryota." ;
  rdfs:subClassOf obo:OBI_0003260 , obo:OBI_0003263 .

obo:OBI_2000012 a rdfs:Class ;
  rdfs:label "umbilical cord blood specimen" ;
  rdfs:comment "A specimen that is derived from some umbilical cord blood" ;
  rdfs:subClassOf obo:OBI_2000013 .

obo:OBCS_0000036 a rdfs:Class ;
  rdfs:label "partitioning of variance components" ;
  rdfs:comment "Partitioning of the overall variation into assignable components" ;
  rdfs:subClassOf obo:OBI_0200000 .

obo:OBCS_0000273 a rdfs:Class ;
  rdfs:label "uncertainty response activity" ;
  rdfs:comment "definition to be confirmed" ;
  rdfs:subClassOf obo:BFO_0000015 .

obo:OBCS_0000358 a rdfs:Class ;
  rdfs:label "societal uncertainty" ;
  rdfs:comment "Communities from one region to another may differ in the set of norms, values, and manner of relating characteristic of their societies. This in turn can result in differences in approach to decision making and assessment. Some salient characteristics of these differences will be different views about the role of consensus versus conflict, on locating responsibility between individuals and larger groups, on views about the legitimacy and role of social and private institutions, and on attitudes to authority and expertise. From De Marchi (1994). Societal uncertainty would typically be high when decisions involve substantial collaboration among groups characterized by divergent decision making styles." ;
  rdfs:subClassOf obo:OBCS_0000251 .

obo:OBI_0200170 a rdfs:Class ;
  rdfs:label "averaging data transformation"@en ;
  rdfs:comment "An averaging data transformation is a data transformation that has objective averaging."@en ;
  rdfs:subClassOf obo:OBI_0200184 .

obo:OBCS_0000143 a rdfs:Class ;
  rdfs:label "experimental validity"@en ;
  rdfs:comment "A validity that refers to whether an experiment (or a study) is able to scientifically answer the questions it is intended to answer." ;
  rdfs:subClassOf obo:OBCS_0000060 .

obo:OBI_0003580 a rdfs:Class ;
  rdfs:label "nasal aspirate microbiology assay" ;
  rdfs:comment "An organism detection assay that detects microorganisms in a nasal aspirate specimen." ;
  rdfs:subClassOf obo:OBI_0003498 .

obo:OBI_0002747 a rdfs:Class ;
  rdfs:label "passage process"@en ;
  rdfs:comment "A material processing that consists of first growing an organism in an environmental system and then removing the organism to be grown in another environmental system, a process which may be repeated with the objective of altering the organism or increasing its number."@en ;
  rdfs:subClassOf obo:OBI_0000094 .

obo:OBCS_0000005 a rdfs:Class ;
  rdfs:label "normal distribution" ;
  rdfs:comment "A continuous probability distribution that has a symmetrical curve, whose position and shape is determined by its location and scale parameters, the mean and standard deviation respectively." ;
  rdfs:subClassOf obo:OBCS_0000066 .

obo:OBI_0200035 a rdfs:Class ;
  rdfs:label "boostrapping"@en ;
  rdfs:comment "Bootstrapping is a statistical method for estimating the sampling distribution of a statistic by sampling with replacement from the original data, most often with the purpose of deriving robust estimates of standard errors and confidence intervals of a population parameter like a mean, median, proportion, odds ratio, correlation coefficient or regression coefficient"@en ;
  rdfs:subClassOf obo:OBI_0000792 .

obo:OBI_0200162 a rdfs:Class ;
  rdfs:label "tail probability for the proportion of false positives correction method"@en ;
  rdfs:comment "A TPPFP correction method is a MTP that controls the probability that the proportion of false positives among all rejected hypotheses is no greater than a constant q, where q is between 0 and 1." ;
  rdfs:subClassOf obo:OBI_0200089 .

obo:OBI_0000741 a rdfs:Class ;
  rdfs:label "topologically preserved clustered data set" ;
  rdfs:comment "A clustered data set in which the topology, i.e. the spatial properties between data points, is preserved from the original input data from which it was derived." ;
  rdfs:subClassOf obo:OBI_0000648 .

obo:OBCS_0000014 a rdfs:Class ;
  rdfs:label "weighted data" ;
  rdfs:comment "A derived data from inferential statistical analysis that is obtained by applying a weighting process to adjust the impact of cases for representing the population from which the data sample is drawn." ;
  rdfs:subClassOf obo:OBCS_0000220 .

obo:OBCS_0000333 a rdfs:Class ;
  rdfs:label "positive or neutral certainty" ;
  rdfs:comment "definition and classification to be confirmed" ;
  rdfs:subClassOf obo:OBCS_0000251 .

obo:OBCS_0000186 a rdfs:Class ;
  rdfs:label "sorting based on numerical order"@en ;
  rdfs:comment "A sorting process that sorts a set of data items based on the numberical order." ;
  rdfs:subClassOf obo:OBCS_0000185 .

obo:OBCS_0000072 a rdfs:Class ;
  rdfs:label "interquartile range" ;
  rdfs:comment "A quantitative confidence value that refers to the upper and lower values defining the central 50 percent of observations. The boundaries are equal to the 25th and 75th percentiles. The interquartile range can be depicted in a box and whiskers plot." ;
  rdfs:subClassOf obo:OBI_0000071 .

obo:OBI_0002769 a rdfs:Class ;
  rdfs:label "karyotype information"@en ;
  rdfs:comment "A genetic characteristics information that is about the number and appearance of chromosomes in the nucleus of an eukaryotic cell."@en ;
  rdfs:subClassOf obo:OBI_0001404 .

obo:OBI_0200154 a rdfs:Class ;
  rdfs:label "agglomerative hierarchical clustering"@en ;
  rdfs:comment "An agglomerative hierarchical clustering is a hierarchical clustering which starts with separate clusters and then successively combines these clusters until there is only one cluster remaining."@en ;
  rdfs:subClassOf obo:OBI_0200042 .

obo:UBERON_0013755 a rdfs:Class ;
  rdfs:label "arterial blood" ;
  rdfs:comment "A blood that is part of a artery." ;
  rdfs:subClassOf obo:UBERON_0000178 .

obo:BFO_0000142 a rdfs:Class ;
  rdfs:label "one-dimensional continuant fiat boundary"@en ;
  rdfs:subClassOf obo:BFO_0000140 .

obo:OBI_0003241 a rdfs:Class ;
  rdfs:label "endotracheal tube aspirate microbiology assay" ;
  rdfs:comment "An organism detection assay that detects microorganisms in an endotracheal aspirate specimen." ;
  rdfs:subClassOf obo:OBI_0003233 , obo:OBI_0003498 .

obo:OBI_0003591 a rdfs:Class ;
  rdfs:label "chronic allograft damage index score"@en ;
  rdfs:comment "A clinical data item that quantifies the degree of tissue damage in biopsies taken from transplanted kidneys." ;
  rdfs:subClassOf obo:OGMS_0000123 .

obo:OBI_0200199 a rdfs:Class ;
  rdfs:label "gas chromatography mass spectrometry" ;
  rdfs:comment """Gas chromatography mass spectrometry is a data transformation combining mass spectrometry and  
gas chromatography for the qualitative as well as quantitative  
determinations of compounds.""" ;
  rdfs:subClassOf obo:OBI_0200085 .

obo:OBI_0001474 a rdfs:Class ;
  rdfs:label "lowess group transformation"@en ;
  rdfs:comment "A lowess transformation where a potentially different normalization curve is generated and used for two or more groups (delineated by some criteria); criteria could include blocks (e.g. print-tip groups) on an array, or the day on which mass spectrometry was performed." ;
  rdfs:subClassOf obo:OBI_0001477 .

obo:OBCS_0000085 a rdfs:Class ;
  rdfs:label "standardized coefficient" ;
  rdfs:comment "A quantitative confidence value that has been standardized so that they have variances of 1.0; produces standardized regression coefficients (betas)" ;
  rdfs:subClassOf obo:OBI_0000071 .

obo:OBCS_0000047 a rdfs:Class ;
  rdfs:label "positive likelihood ratio" ;
  rdfs:comment "A likelihood ratio that is calculated by dividing sensitivity by 1 minus specificity (sensitivity/(1-specificity))." ;
  rdfs:subClassOf obo:OBCS_0000118 .

obo:OBCS_0000243 a rdfs:Class ;
  rdfs:label "log-rank test"@en ;
  rdfs:comment "A non-parametric test that compares the survival distributions of two samples, and iis appropriate to use when the data are right skewed and censored (technically, the censoring must be non-informative). It is widely used in clinical trials to establish the efficacy of a new treatment in comparison with a control treatment when the measurement is the time to event (such as the time from initial treatment to a heart attack)." ;
  rdfs:subClassOf obo:OBCS_0000236 .

obo:OBCS_0000251 a rdfs:Class ;
  rdfs:label "uncertainty" ;
  rdfs:comment "A disposition that inheres in some objects, which prevents accurate prediction or determination of the quality of a material entity. It is realized in objective process or subjective process." ;
  rdfs:subClassOf obo:BFO_0000016 .

obo:OBCS_0000336 a rdfs:Class ;
  rdfs:label "detrimental uncertainty" ;
  rdfs:comment "definition and classification to be confirmed" ;
  rdfs:subClassOf obo:OBCS_0000251 .

obo:OBI_0003248 a rdfs:Class ;
  rdfs:label "urine microbiology datum" ;
  rdfs:comment "An organism detection datum that is the specified output of a urine microbiology assay." ;
  rdfs:subClassOf obo:OBI_0003064 , obo:OBI_0003247 .

obo:OBI_0000789 a rdfs:Class ;
  rdfs:label "survival rate" ;
  rdfs:comment "A measurement data that represents the percentage of people or animals in a study or treatment group who are alive for a given period of time after diagnosis or initiation of monitoring." ;
  rdfs:subClassOf obo:IAO_0000109 .

obo:OBI_0001941 a rdfs:Class ;
  rdfs:label "contig N50"@en ;
  rdfs:comment "N50 statistic computed for the contigs produced by the assembly process. A contig N50 is calculated by first ordering every contig by length from longest to shortest. Next, starting from the longest contig, the lengths of each contig are summed, until this running sum equals one-half of the total length of all contigs in the assembly. The contig N50 of the assembly is the length of the shortest contig in this list." ;
  rdfs:subClassOf obo:OBI_0001940 .

obo:IAO_0000104 a rdfs:Class ;
  rdfs:label "plan specification"@en ;
  rdfs:comment "A directive information entity with action specifications and objective specifications as parts, and that may be concretized as a realizable entity that, if realized, is realized in a process in which the bearer tries to achieve the objectives by taking the actions specified."@en ;
  rdfs:subClassOf obo:IAO_0000033 .

obo:OBI_0600024 a rdfs:Class ;
  rdfs:label "maintaining cell culture"@en ;
  rdfs:comment "A planned process with the objective to keep cells alive in a defined environment outside of an organism."@en ;
  rdfs:subClassOf obo:OBI_0000838 .

obo:OBI_0000443 a rdfs:Class ;
  rdfs:label "analyte assay" ;
  rdfs:comment "An assay with the objective to capture information about the presence, concentration, or amount of an analyte in an evaluant." ;
  rdfs:subClassOf obo:OBI_0000070 .

obo:OBI_0003329 a rdfs:Class ;
  rdfs:label "magnetic resonance imaging participant"@en ;
  rdfs:comment "The subject being scanned in an MRI study, and bearor of data derived from that study." ;
  rdfs:subClassOf obo:BFO_0000040 .

obo:RO_0000053 a rdf:Property ;
  rdfs:label "has characteristic"@en ;
  rdfs:comment "Inverse of characteristic_of"@en ;
  rdfs:range obo:BFO_0000020 .

obo:OBCS_0000369 a rdfs:Class ;
  rdfs:label "high certainty level" ;
  rdfs:comment "definition to be confirmed" ;
  rdfs:subClassOf obo:OBCS_0000367 .

obo:OBI_0200181 a rdfs:Class ;
  rdfs:label "center calculation data transformation"@en ;
  rdfs:comment "A center calculation data transformation is a data transformation that has objective of center calculation."@en ;
  rdfs:subClassOf obo:OBI_0200184 .

obo:OBCS_0000031 a rdfs:Class ;
  rdfs:label "Kolmogorov-Smirnov two sample test" ;
  rdfs:comment "A Kolmogorov-Smirnov test that compares two samples." ;
  rdfs:subClassOf obo:OBCS_0000241 .

obo:OBI_0200128 a rdfs:Class ;
  rdfs:label "directed network graph construction"@en ;
  rdfs:comment "A network graph construction in which an input data set describing objects and directional relationships between objects is transformed into and output representation of these objects as nodes and the directional relationships as directed edges of a network graph."@en ;
  rdfs:subClassOf obo:OBI_0200126 .

obo:UBERON_0001913 a rdfs:Class ;
  rdfs:label "milk" ;
  rdfs:comment "An emulsion of fat globules within a fluid that is secreted by the mammary gland during lactation." ;
  rdfs:subClassOf obo:PR_000050567 , obo:UBERON_0006314 .

obo:OBI_0003066 a rdfs:Class ;
  rdfs:label "easting coordinate measurement datum" ;
  rdfs:comment "A one dimensional Cartesian spatial coordinate datum that is the eastward component of a distance from a point on a map projection." ;
  rdfs:subClassOf obo:IAO_0000401 .

obo:OBCS_0000266 a rdfs:Class ;
  rdfs:label "Numeral Unit Spread Assessment Pedigree" ;
  rdfs:comment "The NUSAP (Numeral Unit Spread Assessment, Pedigree) method aims to provide an analysis and diagnosis of uncertainty. It captures both quantitative dimensions and qualitative dimensions of uncertainty (Funtowicz and Ravetz 1990)." ;
  rdfs:subClassOf obo:OBCS_0000258 .

obo:OBI_0003246 a rdfs:Class ;
  rdfs:label "feces microbiology datum" ;
  rdfs:comment "An organism detection datum that is the specified output of a feces microbiology assay." ;
  rdfs:subClassOf obo:OBI_0003064 , obo:OBI_0003245 .

obo:OBI_0200037 a rdfs:Class ;
  rdfs:label "pareto scaling"@en ;
  rdfs:comment "A pareto scaling is a data transformation that divides all measurements of a variable by the square root of the standard deviation of that variable."@en ;
  rdfs:subClassOf obo:OBI_0200169 .

obo:OBI_0302867 a rdfs:Class ;
  rdfs:label "predicted data item"@en ;
  rdfs:comment "A data item that was generated on the basis of a calculation or logical reasoning"@en ;
  rdfs:subClassOf obo:IAO_0000027 .

obo:OBI_0200196 a rdfs:Class ;
  rdfs:label "correlation study objective" ;
  rdfs:comment "A data transformation objective in which correlation is obtained (often measured as a correlation coefficient, ρ) which indicates the strength and direction of a relationship between two random variables." ;
  rdfs:subClassOf obo:OBI_0200166 .

obo:OBCS_0000306 a rdfs:Class ;
  rdfs:label "division of data along political line for clarity" ;
  rdfs:comment "definition to be confirmed" ;
  rdfs:subClassOf obo:OBCS_0000273 .

obo:OBCS_0000170 a rdfs:Class ;
  rdfs:label "sum value"@en ;
  rdfs:comment "A data item that is produced as the output of a summing data transformation and represents the total value of the input data." ;
  rdfs:subClassOf obo:OBCS_0000233 .

obo:BFO_0000002 a rdfs:Class ;
  rdfs:label "continuant"@en ;
  rdfs:comment "An entity that exists in full at any time in which it exists at all, persists through time while maintaining its identity and has no temporal parts."@en ;
  rdfs:subClassOf obo:BFO_0000001 .

obo:OBCS_0000049 a rdfs:Class ;
  rdfs:label "accuracy" ;
  rdfs:comment "A data item that refers to the number of true positives and true negatives divided by the total number of observations." ;
  rdfs:subClassOf obo:OBCS_0000220 .

obo:OBI_0000953 a rdfs:Class ;
  rdfs:label "processed specimen" ;
  rdfs:comment "A specimen that has been intentionally physically modified." ;
  rdfs:subClassOf obo:OBI_0000047 , obo:OBI_0100051 .

obo:STATO_0000045 a rdfs:Class ;
  rdfs:label "two-way ANOVA"@en ;
  rdfs:comment "two-way anova is an analysis of variance where the different groups being compared are associated the factor levels of exatly 2 independent variables. The null hypothesis is an absence of difference between the means calculated for each of the groups. The test assumes normality and equivariance of the data."@en ;
  rdfs:subClassOf obo:OBI_0200201 .

obo:OBI_0001571 a rdfs:Class ;
  rdfs:label "equilibrium dissociation constant (KD) approximated by IC50" ;
  rdfs:comment "A measurement of an IC50 value under specific assay conditions approximates KD, namely the binding reaction is at an equilibrium, there is a single population of sites on the receptor that competitor and ligand are binding to, and the concentration of the receptor must be much less than the KD for the competitor and the ligand.  In this case, according to Cheng and Prussoff, KD = IC50 / (1 + Lstot / KDs), in which Lstot is the total concentration of the labeled competitor and KDs is the KD value of that competitor." ;
  rdfs:subClassOf obo:OBI_0001536 , obo:OBI_0003144 .

obo:OBI_0000700 a rdfs:Class ;
  rdfs:label "support vector machine" ;
  rdfs:comment "A support vector machine is a data transformation with a class prediction objective based on the construction of a separating hyperplane that maximizes the margin between two data sets of vectors in n-dimensional space." ;
  rdfs:subClassOf obo:OBI_0000663 .

obo:OBI_0003286 a rdfs:Class ;
  rdfs:label "urine microbiology assay" ;
  rdfs:comment "An organism detection assay that detects microorganisms in a urine specimen." ;
  rdfs:subClassOf obo:OBI_0003043 , obo:OBI_0003498 .

obo:OBCS_0000362 a rdfs:Class ;
  rdfs:label "psychological uncertainty" ;
  rdfs:comment "A belief is psychologically certain when the subject who has it is supremely convinced of its truth. Certainty in this sense is similar to incorrigibility, which is the property a belief has of being such that the subject is incapable of giving it up. But psychological certainty is not the same thing as incorrigibility. A belief can be certain in this sense without being incorrigible; this may happen, for example, when the subject receives a very compelling bit of counterevidence to the (previously) certain belief and gives it up for that reason. Moreover, a belief can be incorrigible without being psychologically certain. For example, a mother may be incapable of giving up the belief that her son did not commit a gruesome murder, and yet, compatible with that inextinguishable belief, she may be tortured by doubt. " ;
  rdfs:subClassOf obo:OBCS_0000253 .

obo:OBCS_0000261 a rdfs:Class ;
  rdfs:label "global sensitivity analysis" ;
  rdfs:comment "Model evaluation performed by varying uncertain factors throughout their entire feasible value space." ;
  rdfs:subClassOf obo:OBCS_0000259 .

obo:OBCS_0000059 a rdfs:Class ;
  rdfs:label "specificity" ;
  rdfs:comment "A data item that refers to the proportion of negatives in a binary classification test which are correctly identified" ;
  rdfs:subClassOf obo:OBCS_0000220 .

obo:OBI_0000011 a rdfs:Class ;
  rdfs:label "planned process"@en ;
  rdfs:comment "A process that realizes a plan which is the concretization of a plan specification."@en ;
  rdfs:subClassOf obo:BFO_0000015 .

obo:OBI_0001931 a rdfs:Class ;
  rdfs:label "scalar value specification" ;
  rdfs:comment "A value specification that consists of two parts: a numeral and a unit label" ;
  rdfs:subClassOf obo:OBI_0001933 .

obo:OBI_0001937 a rdf:Property ;
  rdfs:label "has specified numeric value" ;
  rdfs:comment "A relation between a value specification and a number that quantifies it." ;
  rdfs:range <https://w3id.org/linkml/Any> ;
  rdfs:subPropertyOf obo:OBI_0002135 .

obo:OBCS_0000276 a rdfs:Class ;
  rdfs:label "individual difference" ;
  rdfs:comment "definition to be confirmed" ;
  rdfs:subClassOf obo:OBCS_0000272 .

obo:BFO_0000008 a rdfs:Class ;
  rdfs:label "temporal region"@en ;
  rdfs:subClassOf obo:BFO_0000003 .

obo:STATO_0000260 a rdfs:Class ;
  rdfs:label "repeated measure ANOVA" ;
  rdfs:comment """repeated measure ANOVA is a kind of ANOVA specifically developed for non-independent observations as found when repeated measurements on the sample experimental unit. 
repeated measure ANOVA is sensitive to departure from normality (evaluation using Bartlett's test), more so in the case of unbalanced groups (i.e. different sizes of sample populations).
Departure from sphericity (evaluation  using Mauchly'test)  used to be an issue which is now handled robustly by modern tools such as R's lme4 or nlme, which accommodate dependence assumptions other than sphericity."""@en ;
  rdfs:subClassOf obo:OBI_0200201 , obo:STATO_0000202 .

obo:OBCS_0000195 a rdfs:Class ;
  rdfs:label "discrete data value"@en ;
  rdfs:comment "A data value that is discrete, ie, counted." ;
  rdfs:subClassOf obo:OBCS_0000193 .

obo:OBI_0001165 a rdfs:Class ;
  rdfs:label "age since coitus measurement datum"@en ;
  rdfs:comment "An age measurement datum that is the result of the measurement of the age of an organism since coitus, the process of copulation that occurs during the process of sexual reproduction." ;
  rdfs:subClassOf obo:OBI_0001167 .

obo:OBCS_0000211 a rdfs:Class ;
  rdfs:label "Box-Cox distribution"@en ;
  rdfs:comment "A normal distribution that is the distribution of a random variable X for which the Box–Cox transformation on X follows a truncated normal distribution." ;
  rdfs:subClassOf obo:OBCS_0000005 .

obo:OBI_0200099 a rdfs:Class ;
  rdfs:label "discriminant function analysis"@en ;
  rdfs:comment "Discriminant function analysis is a form of discriminant analysis used to determine which variables discriminate between two or more naturally occurring groups. Analysis is used to determine which variable(s) are the best predictors of a particular outcome."@en ;
  rdfs:subClassOf obo:APOLLO_SV_00000796 , obo:OBI_0000663 , obo:OBI_0200106 , obo:OBI_0200175 .

obo:OBCS_0000157 a rdfs:Class ;
  rdfs:label "discriminant validity"@en ;
  rdfs:comment "A construct validity that tests whether concepts or measurements that are supposed to be unrelated are, in fact, unrelated." ;
  rdfs:subClassOf obo:OBCS_0000155 .

obo:OBI_0003280 a rdfs:Class ;
  rdfs:label "virus in pleural fluid datum" ;
  rdfs:comment "A pleural fluid microbiology datum that is about a virus." ;
  rdfs:subClassOf obo:OBI_0003258 .

obo:OBCS_0000340 a rdfs:Class ;
  rdfs:label "measurement uncertainty" ;
  rdfs:comment "Measurement uncertainty stems from the fact that measurements can practically never precisely represent the ‘‘true’’ value of that which is being measured." ;
  rdfs:subClassOf obo:OBCS_0000339 .

obo:IAO_0000033 a rdfs:Class ;
  rdfs:label "directive information entity"@en ;
  rdfs:comment "An information content entity whose concretizations indicate to their bearer how to realize them in a process."@en ;
  rdfs:subClassOf obo:IAO_0000030 .

obo:IAO_0000306 a rdfs:Class ;
  rdfs:label "table"@en ;
  rdfs:comment "A textual entity that contains a two-dimensional arrangement of texts repeated at regular intervals across a spatial range, such that the spatial relationships among the constituent texts expresses propositions"@en ;
  rdfs:subClassOf obo:IAO_0000300 .

obo:OBI_0200032 a rdfs:Class ;
  rdfs:label "K-fold cross validation method"@en ;
  rdfs:comment "K-fold cross-validation randomly partitions the original sample into K subsamples. Of the K subsamples, a single subsample is retained as the validation data for testing the model, and the remaining K - 1 subsamples are used as training data. The cross-validation process is then repeated K times (the folds), with each of the K subsamples used exactly once as the validation data. The K results from the folds then can be averaged (or otherwise combined) to produce a single estimation. The advantage of this method over repeated random sub-sampling is that all observations are used for both training and validation, and each observation is used for validation exactly once. 10-fold cross-validation is commonly used" ;
  rdfs:subClassOf obo:OBI_0000792 .

obo:OBI_0002662 a rdfs:Class ;
  rdfs:label "bone marrow biopsy" ;
  rdfs:comment "A biopsy where a small amount of bone and a small amount of fluid and bone marrow are collected." ;
  rdfs:subClassOf obo:OBI_0002650 .

obo:OBCS_0000367 a rdfs:Class ;
  rdfs:label "uncertainty degree level" ;
  rdfs:comment "definition to be confirmed" ;
  rdfs:subClassOf obo:IAO_0000027 .

obo:IAO_0000401 a rdfs:Class ;
  rdfs:label "one dimensional cartesian spatial coordinate datum"@en ;
  rdfs:comment "A cartesion spatial coordinate datum that  uses one value to specify a position along a one dimensional spatial region"@en ;
  rdfs:subClassOf obo:IAO_0000400 .

obo:OBI_0002982 a rdfs:Class ;
  rdfs:label "reference gene sequence stop site" ;
  rdfs:comment "The position of the last nucelotide in a reference sequence (sequence being used for comparison)." ;
  rdfs:subClassOf obo:OBI_0000973 .

obo:SO_0000148 a rdfs:Class ;
  rdfs:label "supercontig" ;
  rdfs:comment "One or more contigs that have been ordered and oriented using end-read information. Contains gaps that are filled with N's." ;
  rdfs:subClassOf obo:SO_0000353 .

obo:OBCS_0000012 a rdfs:Class ;
  rdfs:label "outlier" ;
  rdfs:comment "A data item that is numerically distant from the rest of the data; often indicative either measurement error or that the population has a high kurtosis." ;
  rdfs:subClassOf obo:OBCS_0000220 .

obo:OBI_0200088 a rdfs:Class ;
  rdfs:label "Kaplan Meier"@en ;
  rdfs:comment "a nonparametric (actuarial) data transformation technique for estimating time-related events. It is a univariate analysis that estimates the probability of the proportion of subjects in remission at a particular time, starting from the initiation of active date (time zero), and takes into account those lost to follow-up or not yet in remission at end of study (censored)" ;
  rdfs:subClassOf obo:OBCS_0000121 , obo:OBI_0200194 .

obo:OBI_0200163 a rdfs:Class ;
  rdfs:label "false discovery rate correction method"@en ;
  rdfs:comment "The false discovery rate is a  data transformation used in multiple hypothesis testing to correct for multiple comparisons. It controls the expected proportion of incorrectly rejected null hypotheses (type I errors) in a list of rejected hypotheses. It is a less conservative comparison procedure with greater power than familywise error rate (FWER) control, at a cost of increasing the likelihood of obtaining type I errors. ." ;
  rdfs:subClassOf obo:APOLLO_SV_00000796 , obo:OBI_0200089 .

obo:OBI_0002579 a rdfs:Class ;
  rdfs:label "adapter-trimmed sequence data" ;
  rdfs:comment "The results of a data transformation of sequence data in which reference subsequences corresponding to ligated library adapters are removed." ;
  rdfs:subClassOf obo:OBI_0000973 .

obo:OBCS_0000087 a rdfs:Class ;
  rdfs:label "nonlinear regression" ;
  rdfs:comment "A form of regression analysis in which observational data are modeled by a function which is a nonlinear combination of the model parameters and depends on one or more independent variables" ;
  rdfs:subClassOf obo:OBI_0200102 .

obo:OBCS_0000126 a rdfs:Class ;
  rdfs:label "random variable"@en ;
  rdfs:comment "A statistical variable whose value is subject to variations due to chance (i.e. randomness, in a mathematical sense)." ;
  rdfs:subClassOf obo:OBCS_0000038 .

obo:OBI_0003365 a rdfs:Class ;
  rdfs:label "milk assay datum" ;
  rdfs:comment "A data item that is the specified output of a milk assay." ;
  rdfs:subClassOf obo:IAO_0000027 .

obo:OBCS_0000076 a rdfs:Class ;
  rdfs:label "range" ;
  rdfs:comment "A quantitative confidence value that equals the difference between the largest and smallest observation." ;
  rdfs:subClassOf obo:OBI_0000071 .

obo:UBERON_0000061 a rdfs:Class ;
  rdfs:label "anatomical structure" ;
  rdfs:comment "Material anatomical entity that is a single connected structure with inherent 3D shape generated by coordinated expression of the organism's own genome." ;
  rdfs:subClassOf obo:UBERON_0000465 .

obo:OBI_0001294 a rdfs:Class ;
  rdfs:label "wild type organism genotype information"@en ;
  rdfs:comment "a genotype information about an organism and includes information that there are no known modifications to the genetic background. Generally it is the genotype information of a representative individual from a class of organisms."@en ;
  rdfs:subClassOf obo:OBI_0001305 .

obo:OBCS_0000139 a rdfs:Class ;
  rdfs:label "data collection by censoring"@en ;
  rdfs:comment "A data collection by sampling process that results in a collection of data generated from an censoring." ;
  rdfs:subClassOf obo:OBCS_0000132 .

obo:OBI_0003257 a rdfs:Class ;
  rdfs:label "nasopharyngeal or oropharyngeal swab microbiology datum" ;
  rdfs:comment "An organism detection datum that is the specified output of a nasopharyngeal or oropharyngeal swab microbiology assay." ;
  rdfs:subClassOf obo:OBI_0003064 .

obo:OBI_0200174 a rdfs:Class ;
  rdfs:label "curve fitting objective"@en ;
  rdfs:comment "A curve fitting objective is a data transformation objective in which the aim is to find a curve which matches a series of data points and possibly other constraints."@en ;
  rdfs:subClassOf obo:OBI_0200166 .

obo:OBCS_0000296 a rdfs:Class ;
  rdfs:label "uncontrollable procedure" ;
  rdfs:comment "definition to be confirmed" ;
  rdfs:subClassOf obo:OBCS_0000272 .

obo:OBCS_0000356 a rdfs:Class ;
  rdfs:label "legal uncertainty" ;
  rdfs:comment "Legal uncertainty is relevant \"wherever agents must consider future contingencies of personal liability for their actions (or inactions)\". High legal uncertainty can result in defensive responses in regard to both decision making and release of information. Legal uncertainty may also play a role where actions are conditioned on the clarity or otherwise of a legal framework in allowing one to predict the consequences of particular actions." ;
  rdfs:subClassOf obo:OBCS_0000251 .

obo:OBI_0200026 a rdfs:Class ;
  rdfs:label "total intensity transformation single"@en ;
  rdfs:comment "A total intensity transformation single is a data transformation that takes as input an n-dimensional (real) vector and multiplies each component of this vector by a coefficient, where the coefficient is obtained by taking the sum of the input components or of a subset of these, multiplied by a constant of choice."@en ;
  rdfs:subClassOf obo:OBI_0200169 .

obo:STATO_0000145 a rdfs:Class ;
  rdfs:label "geometric distribution"@en ;
  rdfs:comment """the geometric distribution is a negative binomial distribution where r is 1.
It is useful for modeling the runs of consecutive successes (or failures) in repeated independent trials of a system.

The geometric distribution models the number of successes before one failure in an independent succession of tests where each test results in success or failure.


The geometric distribution with prob = p has density

p(x) = p (1-p)^x

for x = 0, 1, 2, …, 0 < p ≤ 1.

If an element of x is not integer, the result of dgeom is zero, with a warning.

The quantile is defined as the smallest value x such that F(x) ≥ p, where F is the distribution function."""@en ;
  rdfs:subClassOf obo:STATO_0000283 .

obo:OBCS_0000222 a rdfs:Class ;
  rdfs:label "normal distribution transformation"@en ;
  rdfs:comment "A data transformation process that transforms a data set to a normal distribution." ;
  rdfs:subClassOf obo:APOLLO_SV_00000796 , obo:OBCS_0000188 .

obo:OBCS_0000293 a rdfs:Class ;
  rdfs:label "delay and lack of communication between investigators" ;
  rdfs:comment "definition to be confirmed" ;
  rdfs:subClassOf obo:OBCS_0000272 .

obo:OBI_0001182 a rdfs:Class ;
  rdfs:label "negative binding datum" ;
  rdfs:comment "A categorical binding datum that states that there is no significant disposition of two or more entities to form a complex." ;
  rdfs:subClassOf obo:OBI_0003141 .

obo:OBI_0302910 a rdfs:Class ;
  rdfs:label "prediction"@en ;
  rdfs:comment "a process by which an  event or an entity is described before it actually happens or is being discovered and identified."@en ;
  rdfs:subClassOf obo:OBI_0000011 .

obo:OBCS_0000003 a rdfs:Class ;
  rdfs:label "F distribution" ;
  rdfs:comment "A continuous probability distribution that is associated with the f statistic." ;
  rdfs:subClassOf obo:OBCS_0000066 .

obo:OBCS_0000023 a rdfs:Class ;
  rdfs:label "multivariate analysis" ;
  rdfs:comment "An inferential statistical data analysis that is used to analyze data that arises from more than one variable" ;
  rdfs:subClassOf obo:OBCS_0000121 .

obo:OBI_0002777 a rdfs:Class ;
  rdfs:label "cytometry analysis by manual gating" ;
  rdfs:comment "A gating in which the output of a flow- or mass- cytometry experiment is separated into gates that were set by a human operator in order to quantify the frequency of different cell populations of interest." ;
  rdfs:subClassOf obo:OBI_0200077 .

obo:OBCS_0000161 a rdfs:Class ;
  rdfs:label "predictive validity"@en ;
  rdfs:comment "A criterion validity that refers to the degree to which the operationalization can predict (or correlate with) other measures of the same construct that are measured at some time in the future. With the selection test example, this would mean that the tests are administered to applicants, all applicants are hired, their performance is reviewed at a later time, and then their scores on the two measures are correlated." ;
  rdfs:subClassOf obo:OBCS_0000159 .

obo:OBI_0200185 a rdfs:Class ;
  rdfs:label "scaling data transformation"@en ;
  rdfs:comment "A scaling data transformation is a data transformation that has objective scaling."@en ;
  rdfs:subClassOf obo:OBI_0200000 .

obo:OBI_0001171 a rdfs:Class ;
  rdfs:label "half life datum (t 1/2)" ;
  rdfs:comment "The time it takes for 50% of a class of stochastic processes to occur." ;
  rdfs:subClassOf obo:IAO_0000416 .

obo:OBI_0003081 a rdfs:Class ;
  rdfs:label "extraction date" ;
  rdfs:comment "A time measurement datum that specifies when some material was extracted from an input material." ;
  rdfs:subClassOf obo:IAO_0000416 .

obo:STATO_0000256 a rdfs:Class ;
  rdfs:label "manhattan plot for gwas"@en ;
  rdfs:comment "a manhattan plot for gwas is a kind of scatter plot used to facilitate presentation of genome-wide association study (GWAS) data. Genomic coordinates are displayed along the X-axis, with the negative logarithm of the association P-value for each single nucleotide polymorphism displayed on the Y-axis."@en ;
  rdfs:subClassOf obo:IAO_0000184 .

obo:IAO_0000064 a rdfs:Class ;
  rdfs:label "algorithm"@en ;
  rdfs:comment "A plan specification which describes the inputs and output of mathematical functions as well as workflow of execution for achieving an predefined objective. Algorithms are realized usually by means of implementation as computer programs for execution by automata."@en ;
  rdfs:subClassOf obo:IAO_0000104 .

obo:OBI_0000437 a rdfs:Class ;
  rdfs:label "analyte measurement objective"@en ;
  rdfs:comment "an assay objective to determine the presence or concentration of an analyte in the evaluant"@en ;
  rdfs:subClassOf obo:OBI_0000441 .

obo:PATO_0000161 a rdfs:Class ;
  rdfs:label "rate" ;
  rdfs:comment "A quality of a single process inhering in a bearer by virtue of the bearer's occurrence per unit time." ;
  rdfs:subClassOf obo:PATO_0000001 .

obo:OBCS_0000250 a rdfs:Class ;
  rdfs:label "least square regression"@en ;
  rdfs:comment "A regression analysis method that the overall solution minimizes the sum of the squares of the residuals made in the results of every single equation." ;
  rdfs:subClassOf obo:OBI_0200102 .

obo:STATO_0000524 a rdfs:Class ;
  rdfs:label "Matthews correlation coefficient" ;
  rdfs:comment "Matthews Correlation Coefficient (or MCC) is a correlation coefficient which is a measure of the quality of binary (two-class) classifications, introduced by biochemist Brian W. Matthews in 1975." ;
  rdfs:subClassOf obo:STATO_0000142 .

obo:UBERON_0013522 a rdfs:Class ;
  rdfs:label "subdivision of tube" ;
  rdfs:subClassOf obo:UBERON_0000064 .

obo:OBCS_0000334 a rdfs:Class ;
  rdfs:label "detrimental certainty" ;
  rdfs:comment "definition and classification to be confirmed" ;
  rdfs:subClassOf obo:OBCS_0000251 .

obo:OBCS_0000216 a rdfs:Class ;
  rdfs:label "mathematic graph"@en ;
  rdfs:comment "An information content entity that represents a set of objects (vertices or nodes) where some pairs of objects are connected by links." ;
  rdfs:subClassOf obo:IAO_0000030 .

obo:OBCS_0000168 a rdfs:Class ;
  rdfs:label "differential expression analysis using LIMMA linear models for microarry data"@en ;
  rdfs:comment "A differential expression analysis using LIMMA linear model to identify differential expression for microarray data." ;
  rdfs:subClassOf obo:OBCS_0000121 .

obo:OBCS_0000038 a rdfs:Class ;
  rdfs:label "statistical variable" ;
  rdfs:comment "A directive information entity that specifies a data item that can be measured or counted and is used in a statistical analysis." ;
  rdfs:subClassOf obo:IAO_0000033 .

obo:OBCS_0000287 a rdfs:Class ;
  rdfs:label "specialist/nonspecialist handling of the same case" ;
  rdfs:comment "definition to be confirmed" ;
  rdfs:subClassOf obo:OBCS_0000272 .

obo:OBCS_0000150 a rdfs:Class ;
  rdfs:label "standardized mortality ratio"@en ;
  rdfs:comment "A data item which is the ratio of observed deaths in the study group to expected deaths in the general population." ;
  rdfs:subClassOf obo:OBCS_0000220 .

obo:OBI_0002503 a rdfs:Class ;
  rdfs:label "feces specimen" ;
  rdfs:comment "A specimen that is derived from feces." ;
  rdfs:subClassOf obo:OBI_0001479 .

obo:OBI_0200191 a rdfs:Class ;
  rdfs:label "gene list visualization" ;
  rdfs:comment "Adata visualization which has input of a gene list and produces an output of a report graph which is capable of rendering data of this type." ;
  rdfs:subClassOf obo:OBI_0200111 .

obo:OBCS_0000272 a rdfs:Class ;
  rdfs:label "uncertainty arise condition" ;
  rdfs:comment "definition to be confirmed" ;
  rdfs:subClassOf obo:BFO_0000015 .

obo:OBCS_0000146 a rdfs:Class ;
  rdfs:label "2x2 contingency table"@en ;
  rdfs:comment "A contingency table with two rows and two columns that reports the number of false positives, false negatives, true positives, and true negatives. This allows more detailed analysis than mere proportion of correct guesses (accuracy)." ;
  rdfs:subClassOf obo:OBCS_0000145 .

obo:IAO_0000037 a rdfs:Class ;
  rdfs:label "dot plot"@en ;
  rdfs:comment "A dot plot is a report graph which is a graphical representation of data where each data point is represented by a single dot placed on coordinates corresponding to data point values in particular dimensions."@en ;
  rdfs:subClassOf obo:IAO_0000038 .

obo:OBI_0000274 a rdfs:Class ;
  rdfs:label "adding a material entity into a target"@en ;
  rdfs:comment "is a process with the objective to place a material entity bearing the 'material to be added role' into a material bearing the 'target of material addition role'."@en ;
  rdfs:subClassOf obo:OBI_0000652 .

obo:OBI_0200180 a rdfs:Class ;
  rdfs:label "spread calculation objective"@en ;
  rdfs:comment "is a data transformation objective whereby the aim is to the calculate the spread of a dataset, spread is a descriptive statistic which describes the variability of values in a data set." ;
  rdfs:subClassOf obo:OBI_0200166 .

obo:OBCS_0000045 a rdfs:Class ;
  rdfs:label "Poisson distribution" ;
  rdfs:comment "A discrete probability distribution that expresses the probability of a given number of events occurring in a fixed interval of time and/or space if these events occur with a known average rate and independently of the time since the last event. The Poisson distribution can also be used for the number of events in other specified intervals such as distance, area or volume." ;
  rdfs:subClassOf obo:OBCS_0000067 .

obo:CL_0000578 a rdfs:Class ;
  rdfs:label "experimentally modified cell in vitro" ;
  rdfs:comment "A cell in vitro that has undergone physical changes as a consequence of a deliberate and specific experimental procedure." ;
  rdfs:subClassOf obo:CL_0001034 .

obo:OBI_0200073 a rdfs:Class ;
  rdfs:label "family wise error rate correction method"@en ;
  rdfs:comment "A family wise error rate correction method is a multiple testing procedure that controls the probability of at least one false positive." ;
  rdfs:subClassOf obo:APOLLO_SV_00000796 , obo:OBI_0200089 .

obo:OBCS_0000238 a rdfs:Class ;
  rdfs:label "Durbin test"@en ;
  rdfs:comment "A non-parametric test that was proposed by James Durbin and is used for for balanced incomplete designs." ;
  rdfs:subClassOf obo:OBCS_0000236 .

obo:OBI_0000441 a rdfs:Class ;
  rdfs:label "assay objective"@en ;
  rdfs:comment "an objective specification to determine a specified type of information about an evaluated entity (the material entity bearing evaluant role)"@en ;
  rdfs:subClassOf obo:IAO_0000005 .

obo:OBI_0200072 a rdfs:Class ;
  rdfs:label "curve fitting data transformation"@en ;
  rdfs:comment "A curve fitting is a data transformation that has objective curve fitting and that consists of finding a curve which matches a series of data points and possibly other constraints."@en ;
  rdfs:subClassOf obo:OBCS_0000121 .

obo:UBERON_0004121 a rdfs:Class ;
  rdfs:label "ectoderm-derived structure" ;
  rdfs:comment "An anatomical structure that develops (entirely or partially) from the ectoderm." ;
  rdfs:subClassOf obo:UBERON_0000061 .

obo:UBERON_0002048 a rdfs:Class ;
  rdfs:label "lung" ;
  rdfs:comment "Respiration organ that develops as an outpocketing of the esophagus." ;
  rdfs:subClassOf obo:UBERON_0000062 , obo:UBERON_0004119 .

obo:OBI_0001418 a rdfs:Class ;
  rdfs:label "dose response design" ;
  rdfs:comment "A study design that examines the relationship between the size of the administered dose and the extent of the response." ;
  rdfs:subClassOf obo:OBI_0000951 .

obo:OBCS_0000184 a rdfs:Class ;
  rdfs:label "knuth shuffle"@en ;
  rdfs:comment "A random permutation process that generates a permutation of n items uniformly at random without retries. Specifically, it is to start with any permutation (for example, the identity permutation), and then go through the positions 1 through n − 1, and for each position i swap the element currently there with a randomly chosen element from positions i through n, inclusive." ;
  rdfs:subClassOf obo:OBCS_0000179 .

obo:OBCS_0000351 a rdfs:Class ;
  rdfs:label "external driving forces uncertainty" ;
  rdfs:comment "Uncertainty about the external driving forces that produce changes within the system (the relevant scenario variables and policy variables) and the magnitude of the forces (the values of the scenario and policy variables). " ;
  rdfs:subClassOf obo:OBCS_0000350 .

obo:STATO_0000241 a rdfs:Class ;
  rdfs:label "Q-Q plot"@en ;
  rdfs:comment "Q-Q plot or quantile-quantile plot is the output of a graphical method for comparing two probability distributions by plotting their quantiles against each other"@en ;
  rdfs:subClassOf obo:IAO_0000038 .

obo:OBI_0500012 a rdfs:Class ;
  rdfs:label "graeco latin square design" ;
  rdfs:comment "Greco-Latin square design is a study design which relates to Latin square design" ;
  rdfs:subClassOf obo:OBI_0500007 .

obo:OBCS_0000016 a rdfs:Class ;
  rdfs:label "mode" ;
  rdfs:comment "A data item that is the value that appears most frequent in a set of data. In a normal distribution the numerical value of the mode is the same as that of the mean and median." ;
  rdfs:subClassOf obo:OBI_0000674 .

obo:STATO_0000123 a rdfs:Class ;
  rdfs:label "r2 measure of linkage desequilibrium"@en ;
  rdfs:comment "r2 is a correlation coefficient which is computed over the frequency of 2 dichotomous variable and is used as a measure of Linkage Disequilibrium and as input data item to the creation of an LD plot"@en ;
  rdfs:subClassOf obo:STATO_0000142 .

obo:OBI_0000242 a rdfs:Class ;
  rdfs:label "software testing objective"@en ;
  rdfs:comment "Software_testing_objective is a hardware_optimization role describing a study designed to examine the effects of using different software or software parameters, e.g. data processing software."@en ;
  rdfs:subClassOf obo:OBI_0000208 .

obo:OBI_0000676 a rdfs:Class ;
  rdfs:label "reduced dimension data set"@en ;
  rdfs:comment "A data set that is produced as the output of a data vector reduction data transformation and consists of producing a data set which has fewer vectors than the input data set."@en ;
  rdfs:subClassOf obo:OBCS_0000123 , obo:OBCS_0000220 .

obo:OBCS_0000265 a rdfs:Class ;
  rdfs:label "expert elicitation" ;
  rdfs:comment "A structured process to elicit subjective judgements from experts. Expert elicitation in the context of uncertainty quantification aims at a credible and traceable  account of specifying probabilistic information regarding uncertainty, in a structured and documented way." ;
  rdfs:subClassOf obo:OBCS_0000258 .

obo:OBI_0200100 a rdfs:Class ;
  rdfs:label "canonical variate analysis"@en ;
  rdfs:comment "canonical variate analysis is a form of discriminant analysis that takes several continuous predictor variables and uses the entire set to predict several criterion variables, each of which is also continuous. CVA simultaneously calculates a linear composite of all x variables and  a linear composite of all y variables. Unlike other multivariate techniques, these weighted composites are derived in pairs. Each linear combination is called a canonical variate and takes the general linear form."@en ;
  rdfs:subClassOf obo:OBI_0200106 , obo:OBI_0200171 .

obo:OBI_0200008 a rdfs:Class ;
  rdfs:label "hyperlog transformation"@en ;
  rdfs:comment "A hyperlog transformation ia a data transformation that, for each (one dimensional) real number input x, outputs an approximation (found, e.g. with the Newton's method) to a solution y of the equation EH(y)-x=0, where EH denotes an eh transformation."@en ;
  rdfs:subClassOf obo:OBI_0200169 .

obo:UBERON_0000344 a rdfs:Class ;
  rdfs:label "mucosa" ;
  rdfs:comment "A lining of mostly endodermal origin, covered in epithelium, which is involved in absorption and secretion. They line various body cavities that are exposed to the external environment and internal organs. It is at several places continuous with skin: at the nostrils, the lips, the ears, the genital area, and the anus. The sticky, thick fluid secreted by the mucous membranes and gland is termed mucus. The term mucous membrane refers to where they are found in the body and not every mucous membrane secretes mucus[WP]." ;
  rdfs:subClassOf obo:PR_000050567 , obo:UBERON_0000064 .

obo:OBCS_0000244 a rdfs:Class ;
  rdfs:label "Pearson's chi-square test"@en ;
  rdfs:comment "A chi square test that is applied to sets of categorical data to evaluate how likely it is that any observed difference between the sets arose by chance. It is suitable for unpaired data from large samples. It is also the most widely used of many chi-squared tests." ;
  rdfs:subClassOf obo:OBI_0200200 .

obo:UBERON_0007311 a rdfs:Class ;
  rdfs:label "sputum" ;
  rdfs:comment "Matter ejected from the lungs, bronchi, and trachea, through the mouth." ;
  rdfs:subClassOf obo:UBERON_0006538 .

obo:UBERON_0002371 a rdfs:Class ;
  rdfs:label "bone marrow" ;
  rdfs:comment "The soft tissue that fills the cavities of bones." ;
  rdfs:subClassOf obo:UBERON_0000479 .

obo:OBCS_0000181 a rdfs:Class ;
  rdfs:label "MANOVA"@en ;
  rdfs:comment "A multivariate analysis that compares multivariate sample means. As a multivariate procedure, it is used when there are two or more dependent variables." ;
  rdfs:subClassOf obo:OBCS_0000023 .

obo:OBCS_0000054 a rdfs:Class ;
  rdfs:label "odds ratio" ;
  rdfs:comment "A data item that refers to the odds that an individual with a specific condition has been exposed to a risk factor divided by the odds that a control has been exposed. The odds ratio is used in case-control studies. The odds ratio provides a reasonable estimate of the relative risk for uncommon conditions." ;
  rdfs:subClassOf obo:OBCS_0000220 .

obo:OBI_0000671 a rdfs:Class ;
  rdfs:label "sample from organism" ;
  rdfs:comment "a material obtained from an organism in order to be a representative of the whole" ;
  rdfs:subClassOf obo:OBI_0000747 , obo:OBI_0001479 .

obo:IAO_0000181 a rdfs:Class ;
  rdfs:label "Venn diagram"@en ;
  rdfs:comment """A Venn diagram is a report graph showing all hypothetically possible
logical relations between a finite collection of sets."""@en ;
  rdfs:subClassOf obo:IAO_0000038 .

obo:OBI_0001620 a rdfs:Class ;
  rdfs:label "latitude coordinate measurement datum"@en ;
  rdfs:comment "A measurement datum that is the measure of the latitude coordinate of a site."@en ;
  rdfs:subClassOf obo:IAO_0000109 .

obo:OBI_0200040 a rdfs:Class ;
  rdfs:label "modular decomposition"@en ;
  rdfs:comment "Molecular decomposition is the partition of a network into distinct subgraphs for the purpose of identifying functional clusters. The network data is run through any of several existing algorithms designed to partition a network into distinct subgraphs for the purpose of isolating groups of functionally linked biological elements such as proteins."@en ;
  rdfs:subClassOf obo:OBI_0200080 .

obo:IAO_0000101 a rdfs:Class ;
  rdfs:label "image"@en ;
  rdfs:comment "An image is an affine projection to a two dimensional surface, of measurements of some quality of an entity or entities repeated at regular intervals across a spatial range, where the measurements are represented as color and luminosity on the projected on surface."@en ;
  rdfs:subClassOf obo:IAO_0000308 .

obo:OBI_0000185 a rdfs:Class ;
  rdfs:label "imaging assay" ;
  rdfs:comment "An assay that produces a picture of an entity." ;
  rdfs:subClassOf obo:OBI_0000070 .

obo:OBI_0200200 a rdfs:Class ;
  rdfs:label "chi square test" ;
  rdfs:comment "The chi-square test is a data transformation with the objective of statistical hypothesis testing, in which the sampling distribution of the test statistic is a chi-square distribution when the null hypothesis is true, or any in which this is asymptotically true, meaning that the sampling distribution (if the null hypothesis is true) can be made to approximate a chi-square distribution as closely as desired by making the sample size large enough." ;
  rdfs:subClassOf obo:OBI_0000673 .

obo:OBCS_0000249 a rdfs:Class ;
  rdfs:label "independent component analysis"@en ;
  rdfs:comment "An inferential statistical data analysis which is used to find the independent components (also called factors, latent variables or sources) by maximizing the statistical independence of the estimated components." ;
  rdfs:subClassOf obo:OBCS_0000121 .

obo:OBI_0002020 a rdfs:Class ;
  rdfs:label "epigenetic modification assay" ;
  rdfs:comment "An assay that identifies epigenetic modifications including histone modifications, open chromatin, and DNA methylation." ;
  rdfs:subClassOf obo:OBI_0000070 .

obo:UBERON_0006538 a rdfs:Class ;
  rdfs:label "respiratory system fluid/secretion" ;
  rdfs:comment "A portion of organism substance that secreted_by a respiratory system." ;
  rdfs:subClassOf obo:UBERON_0000463 .

obo:OBI_0200103 a rdfs:Class ;
  rdfs:label "multiple linear regression analysis"@en ;
  rdfs:comment """multiple linear regression is a regression method that models the relationship between a dependent variable Y, independent variables Xi, i = 1, ..., p, and a random term epsilon. The model can be written as
    Y = \\beta_0 + \\beta_1 X_1 + \\beta_2 X_2 + \\cdots +\\beta_p X_p + \\varepsilon
where \\beta_0 =  0 is the intercept (\"constant\" term), the \\beta_i s  are the respective parameters of independent variables, and p is the number of parameters to be estimated in the linear regression."""@en ;
  rdfs:subClassOf obo:OBI_0200102 .

obo:OBI_0200010 a rdfs:Class ;
  rdfs:label "loess scale group transformation one-channel"@en ;
  rdfs:comment "A loess scale group transformation one-channel is a loess scale group transformation consisting in the application of a scale adjustment following a loess group transformation one-channel, to render the M group variances similar."@en ;
  rdfs:subClassOf obo:OBI_0200025 .

obo:OBI_0200058 a rdfs:Class ;
  rdfs:label "b cell epitope prediction"@en ;
  rdfs:comment "A B cell epitope prediction takes as input an antigen sequence, and through an analysis of this sequence, produces as output a prediction of the likelihood the biomaterial is a B Cell Epitope."@en ;
  rdfs:subClassOf obo:OBI_0200187 .

obo:OBI_0001619 a rdfs:Class ;
  rdfs:label "specimen collection time measurement datum"@en ;
  rdfs:comment "A time measurement datum that is the measure of the time when the specimens are collected."@en ;
  rdfs:subClassOf obo:IAO_0000416 .

obo:OBI_0200062 a rdfs:Class ;
  rdfs:label "continuum mass spectrum analysis"@en ;
  rdfs:comment "A continuum mass spectrum is a data transformation that contains the full profile of the detected signals for a given ion."@en ;
  rdfs:subClassOf obo:OBI_0200085 .

obo:PATO_0000011 a rdfs:Class ;
  rdfs:label "age" ;
  rdfs:comment "A time quality inhering in a bearer by virtue of how long the bearer has existed." ;
  rdfs:subClassOf obo:PATO_0001018 .

obo:OBCS_0000135 a rdfs:Class ;
  rdfs:label "discrete random variable"@en ;
  rdfs:comment "A random variable which may take on only a countable number of distinct values such as 0, 1, 2, 3, 4, ..." ;
  rdfs:subClassOf obo:OBCS_0000126 .

obo:OBI_0003576 a rdfs:Class ;
  rdfs:label "skin of body microbiology assay" ;
  rdfs:comment "An organism detection assay that detects microorganisms in a skin of body specimen." ;
  rdfs:subClassOf obo:OBI_0003498 .

obo:IAO_0000582 a rdfs:Class ;
  rdfs:label "time stamped measurement datum"@en ;
  rdfs:subClassOf obo:IAO_0000109 .

obo:IAO_0000581 a rdf:Property ;
  rdfs:label "has time stamp"@en ;
  rdfs:comment "relates a time stamped measurement datum to the time measurement datum that denotes the time when the measurement was taken"@en ;
  rdfs:range <https://w3id.org/linkml/Any> ;
  rdfs:subPropertyOf obo:BFO_0000051 .

obo:IAO_0000583 a rdf:Property ;
  rdfs:label "has measurement datum"@en ;
  rdfs:comment "relates a time stamped measurement datum to the measurement datum that was measured"@en ;
  rdfs:range <https://w3id.org/linkml/Any> ;
  rdfs:subPropertyOf obo:BFO_0000051 .

obo:STATO_0000168 a rdfs:Class ;
  rdfs:label "real time quantitative pcr plot"@en ;
  rdfs:comment "a real time quantitative pcr plot is a line graph which plots the signal fluorescence intensity as a function of the number of PCR cycle"@en ;
  rdfs:subClassOf obo:IAO_0000573 .

obo:OBI_0200149 a rdfs:Class ;
  rdfs:label "unit-variance scaling"@en ;
  rdfs:comment "A unit-variance scaling is a data transformation that divides all measurements of a variable by the standard deviation of that variable."@en ;
  rdfs:subClassOf obo:OBI_0200169 .

obo:OBCS_0000027 a rdfs:Class ;
  rdfs:label "cochran-armitage test" ;
  rdfs:comment "A data transformation used in categorical data analysis when the aim is to assess for the presence of an association between a variable with two categories and a variable with k categories." ;
  rdfs:subClassOf obo:OBCS_0000121 .

obo:STATO_0000112 a rdfs:Class ;
  rdfs:label "Funnel plot"@en ;
  rdfs:comment """a Funnel plot is a scatter plot of treatment effect versus a measure of study size and aims to provide a visual aid to detecting bias or systematic heterogeneity. A symmetric inverted funnel shape arises from a ‘well-behaved’ data set, in which publication bias is unlikely. An asymmetric funnel indicates a relationship between treatment effect and study size. 
Known caveats: If high precision studies really are different from low precision studies with respect to effect size (e.g., due to different populations examined) a funnel plot may give a wrong impression of publication bias. The appearance of the funnel plot can change quite dramatically depending on the scale on the y-axis — whether it is the inverse square error or the trial size.
Funnel plot was introduced by Light and Palmer in 1984."""@en ;
  rdfs:subClassOf obo:IAO_0000184 .

obo:OBCS_0000345 a rdfs:Class ;
  rdfs:label "total ignorance" ;
  rdfs:comment "Total ignorance is the other extreme from determinism on the scale of uncertainty, which implies a deep level of uncertainty, to the extent that we do not even know that we do not know. " ;
  rdfs:subClassOf obo:OBCS_0000251 .

obo:OBI_0200111 a rdfs:Class ;
  rdfs:label "data visualization"@en ;
  rdfs:comment "A planned process with the objective to graphically represent some data by inputing the data and outputting images, diagrams or animations."@en ;
  rdfs:subClassOf obo:OBI_0000011 .

obo:OBCS_0000317 a rdfs:Class ;
  rdfs:label "imperfect model" ;
  rdfs:comment "definition to be confirmed" ;
  rdfs:subClassOf obo:OBCS_0000272 .

obo:OBI_0200095 a rdfs:Class ;
  rdfs:label "exponential transformation"@en ;
  rdfs:comment "An exponential transformation is a data transformation consisting in the application of the exponential function with a given base a (where a>0 and a is typically not equal to 1) to a (one dimensional) real number input. For alternative definitions and properties of this function see, e.g., http://en.wikipedia.org/wiki/Exponential_function and http://en.wikipedia.org/wiki/Characterizations_of_the_exponential_function."@en ;
  rdfs:subClassOf obo:OBI_0200169 .

obo:OBCS_0000034 a rdfs:Class ;
  rdfs:label "mcnemar's test" ;
  rdfs:comment "A normal approximation used on nominal data; applied to 2x2 contingency tables to determine whether the row and column marginal frequencies are equal (\"marginal homogeneity\")." ;
  rdfs:subClassOf obo:OBCS_0000121 .

obo:OBI_0200083 a rdfs:Class ;
  rdfs:label "survival analysis objective"@en ;
  rdfs:comment "A data transformation objective which has the data transformation aims to model time to event data (where events are e.g. death and or disease recurrence); the purpose of survival analysis is to model the underlying distribution of event times and to assess the dependence of the event time on other explanatory variables" ;
  rdfs:subClassOf obo:OBI_0200166 .

obo:OBCS_0000104 a rdfs:Class ;
  rdfs:label "balanced design" ;
  rdfs:comment "An experimental design where all cells (i.e. treatment combinations) have the same number of observation" ;
  rdfs:subClassOf obo:OBI_0500000 .

obo:OBI_0001603 a rdfs:Class ;
  rdfs:label "binding off rate measurement datum (koff)" ;
  rdfs:comment "A rate measurement datum of how quickly bound complexes disassociate" ;
  rdfs:subClassOf obo:OBI_0001144 , obo:OBI_0001554 .

obo:OBI_0001874 a rdfs:Class ;
  rdfs:label "random access memory size"@en ;
  rdfs:comment "random access memory size is a scalar measurement datum which denotes the amount of physical memory know as random access memory present of a computer or required by a computational process or data transformation"@en ;
  rdfs:subClassOf obo:IAO_0000032 .

obo:BFO_0000019 a rdfs:Class ;
  rdfs:label "quality"@en ;
  rdfs:subClassOf obo:BFO_0000020 .

obo:OBI_0000434 a rdfs:Class ;
  rdfs:label "adding material objective"@en ;
  rdfs:comment "is the specification of an objective to add a material into a target material. The adding is asymmetric in the sense that the target material largely retains its identity"@en ;
  rdfs:subClassOf obo:OBI_0000686 .

obo:OBI_0000115 a rdfs:Class ;
  rdfs:label "intervention design" ;
  rdfs:comment "An intervention design is a study design in which a controlled process applied to the subjects (the intervention) serves as the independent variable manipulated by the experimentalist. The treatment (perturbation or intervention) defined can be defined as a combination of values taken by independent variable manipulated by the experimentalists are applied to the recruited subjects assigned (possibly by applying specific methods) to treatment groups. The specificity of intervention design is the fact that independent variables are being manipulated and a response of the biological system is evaluated via response variables as monitored by possibly a series of assays." ;
  rdfs:subClassOf obo:OBI_0500000 .

obo:OBI_0003237 a rdfs:Class ;
  rdfs:label "feces assay" ;
  rdfs:comment "An assay that has a feces specimen as evaluant." ;
  rdfs:subClassOf obo:OBI_0000070 .

obo:OBI_0000660 a rdfs:Class ;
  rdfs:label "background corrected data set"@en ;
  rdfs:comment "A data set that is produced as the output of a background correction data transformation."@en ;
  rdfs:subClassOf obo:OBCS_0000123 .

obo:OBCS_0000065 a rdfs:Class ;
  rdfs:label "point prevalence rate" ;
  rdfs:comment "A prevalence rate that occurs at a specific point of time." ;
  rdfs:subClassOf obo:OBCS_0000055 .

obo:UO_0000001 a rdfs:Class ;
  rdfs:label "length unit" ;
  rdfs:subClassOf obo:IAO_0000003 .

obo:STATO_0000267 a rdfs:Class ;
  rdfs:label "grouped bar chart" ;
  rdfs:comment "grouped bar chart is a kind of bar chart which juxtaposes the  discrete values for each of the possible value of a given categorical variable, thus providing  within group comparison. Grouped bar charts are good for comparing between each element in the categories, and comparing elements across categories. However, the grouping can make it harder to tell the difference between the total of each group."@en ;
  rdfs:subClassOf obo:STATO_0000166 .

obo:OBI_0200051 a rdfs:Class ;
  rdfs:label "principal components analysis dimensionality reduction"@en ;
  rdfs:comment "A principal components analysis dimensionality reduction is a dimensionality reduction achieved by applying principal components analysis and by keeping low-order principal components and excluding higher-order ones."@en ;
  rdfs:subClassOf obo:OBI_0200050 .

obo:OBI_0001834 a rdfs:Class ;
  rdfs:label "drawing a conclusion" ;
  rdfs:comment "A planned process in which new information is inferred from existing information." ;
  rdfs:subClassOf obo:OBI_0000011 .

obo:OBCS_0000173 a rdfs:Class ;
  rdfs:label "data collection by web crawling"@en ;
  rdfs:comment "An online data collection process that extracts data from online using a web crawler. A Web crawler is an Internet bot which systematically browses the World Wide Web and gets data from WWW." ;
  rdfs:subClassOf obo:OBCS_0000171 .

obo:OBCS_0000254 a rdfs:Class ;
  rdfs:label "subjective object" ;
  rdfs:comment "An object with subjective cognition." ;
  rdfs:subClassOf obo:BFO_0000030 .

obo:OBI_0200019 a rdfs:Class ;
  rdfs:label "loess group transformation two-channel"@en ;
  rdfs:comment "A loess group transformation two-channel is a loess group transformation in the special case where the input is the result of an MA transformation applied to intensities from the two channels of a two-channel assay."@en ;
  rdfs:subClassOf obo:OBI_0200024 .

obo:OBCS_0000283 a rdfs:Class ;
  rdfs:label "uncontrollable experimental condition" ;
  rdfs:comment "definition to be confirmed" ;
  rdfs:subClassOf obo:OBCS_0000272 .

obo:OBI_0000566 a rdfs:Class ;
  rdfs:label "NMR instrument" ;
  rdfs:comment "An Instrument which is used to carry out a NMR analysis of some sample." ;
  rdfs:subClassOf obo:OBI_0000832 .

obo:OBCS_0000233 a rdfs:Class ;
  rdfs:label "transformed data item"@en ;
  rdfs:comment "A data item that is produced as the output of a data transformation." ;
  rdfs:subClassOf obo:IAO_0000027 .

obo:OBCS_0000330 a rdfs:Class ;
  rdfs:label "organizational uncertainty" ;
  rdfs:comment "Organizational uncertainty arose when information was lost or trapped owing to the local division of labor or the circumstances of alliances and collaborations. " ;
  rdfs:subClassOf obo:OBCS_0000253 .

obo:OBCS_0000328 a rdfs:Class ;
  rdfs:label "taxonomic uncertainty" ;
  rdfs:comment "Taxonomic uncertainty arose as they tried to develop classification systems (for example, what kind of thing was epilepsy?)." ;
  rdfs:subClassOf obo:OBCS_0000252 .

obo:BFO_0000035 a rdfs:Class ;
  rdfs:label "process boundary"@en ;
  rdfs:comment "p is a process boundary =Def. p is a temporal part of a process & p has no proper temporal parts. (axiom label in BFO2 Reference: [084-001])"@en ;
  rdfs:subClassOf obo:BFO_0000003 .

obo:OBI_0003249 a rdfs:Class ;
  rdfs:label "induced sputum assay datum" ;
  rdfs:comment "A data item that is the specified output of a induced sputum assay." ;
  rdfs:subClassOf obo:IAO_0000027 .

obo:OBI_0001913 a rdfs:Class ;
  rdfs:label "computation run time"@en ;
  rdfs:comment "computation run time is a time measurement datum which corresponds the time expressed in second, minute, hour necessary for a computer program to complete a process execution, for example genome assembly. It is an important metrics as it indicates the resource occupancy and computer program efficiency."@en ;
  rdfs:subClassOf obo:IAO_0000416 .

obo:OBCS_0000007 a rdfs:Class ;
  rdfs:label "bivariate normal distribution" ;
  rdfs:comment "A continuous probability distribution of two variables that has the traditional bell shape and the distribution of one variable is normal to each and every value of the other variable." ;
  rdfs:subClassOf obo:OBCS_0000066 .

obo:OBCS_0000192 a rdfs:Class ;
  rdfs:label "rank-order transformation"@en ;
  rdfs:comment "A data transformation that lists data items in a sequential arrangement"@en ;
  rdfs:subClassOf obo:OBCS_0000188 .

obo:OBI_0003381 a rdfs:Class ;
  rdfs:label "placental blood microbiology assay" ;
  rdfs:comment "A blood microbiology assay that detects microorganisms in a placental blood specimen." ;
  rdfs:subClassOf obo:OBI_0002649 .

obo:OBI_0001234 a rdfs:Class ;
  rdfs:label "epigenetic modification identification objective"@en ;
  rdfs:comment "A molecular feature identification objective that aims to detect epigenetic modifications, such as DNA methylation, histone modifications."@en ;
  rdfs:subClassOf obo:OBI_0000131 .

obo:STATO_0000166 a rdfs:Class ;
  rdfs:label "bar chart"@en ;
  rdfs:comment "the bart chart is a graph resulting from plotting rectangular bars with lengths proportional to the values that they represent." ;
  rdfs:subClassOf obo:IAO_0000038 .

obo:OBI_0003267 a rdfs:Class ;
  rdfs:label "eukaryota in urine datum" ;
  rdfs:comment "A urine microbiology datum that is about eukaryota." ;
  rdfs:subClassOf obo:OBI_0003248 .

obo:OBI_0200025 a rdfs:Class ;
  rdfs:label "loess scale group transformation"@en ;
  rdfs:comment "A loess scale group transformation is a data transformation consisting in the application of a scale adjustment following a loess group transformation, to render the group variances for the second variable (y) similar.  Has objective scaling."@en ;
  rdfs:subClassOf obo:OBI_0200185 .

obo:OBI_0200004 a rdfs:Class ;
  rdfs:label "log-log curve fitting"@en ;
  rdfs:comment "A log-log curve fitting is a curve fitting where first a logarithmic transformation is applied both to the x and the y coordinates of the input data points (x_1, y_1), (x_2, y_2), ..., (x_n, y_n), and then coefficients a and b are determined to optimize the fit of log(y)=a+b*log(x) to these input data points."@en ;
  rdfs:subClassOf obo:OBI_0200072 .

obo:OBCS_0000372 a rdfs:Class ;
  rdfs:label "very high uncertainty level" ;
  rdfs:comment "definition to be confirmed" ;
  rdfs:subClassOf obo:OBCS_0000367 .

obo:OBCS_0000142 a rdfs:Class ;
  rdfs:label "signal-2-noise statistical analysis"@en ;
  rdfs:comment "A univariate analysis that calculates  the level of a desired signal to the level of background noise to identify which detected signal is more signal than noise. It can be used to identify differentially expressed genes." ;
  rdfs:subClassOf obo:OBCS_0000025 .

obo:OBCS_0000062 a rdfs:Class ;
  rdfs:label "data sampling design" ;
  rdfs:comment "A plan specification that provides a detailed outline of which measurements will be taken at what times, on which material, in what manner, and by whom. Sampling plans should be designed in such a way that the resulting data will contain a representative sample of the parameters of interest and allow for all questions, as stated in the goals, to be answered. " ;
  rdfs:subClassOf obo:OBCS_0000137 .

obo:OBCS_0000346 a rdfs:Class ;
  rdfs:label "context uncertainty" ;
  rdfs:comment "Context uncertainty includes uncertainty about the external economic, environmental, political, social, and technological situation that forms the context for the problem being examined. The context could fall within the past, the present, or the future. " ;
  rdfs:subClassOf obo:OBCS_0000252 .

obo:OBCS_0000147 a rdfs:Class ;
  rdfs:label "Gene Set Enrichment Analysis"@en ;
  rdfs:comment "An inferential statistical data analysis that determines whether an a priori defined set of genes shows statistically significant, concordant differences between two biological states (e.g. phenotypes)." ;
  rdfs:subClassOf obo:OBCS_0000121 .

obo:OBI_0001265 a rdfs:Class ;
  rdfs:label "FWER adjusted p-value" ;
  rdfs:comment "A quantitative confidence value resulting from a multiple testing error correction method which adjusts the p-value used as input to control for Type I error in the context of multiple pairwise tests"@en ;
  rdfs:subClassOf obo:OBI_0000071 , obo:OBI_0000662 .

obo:OBCS_0000205 a rdfs:Class ;
  rdfs:label "nominal variable"@en ;
  rdfs:comment "A discrete variable that allows for only qualitative classification" ;
  rdfs:subClassOf obo:OBCS_0000201 .

obo:OBI_0200092 a rdfs:Class ;
  rdfs:label "Westfall and Young family wise error rate correction"@en ;
  rdfs:comment "Is a data transformation process in which the Westfall and Young method is applied with the aim of controlling for multiple testing" ;
  rdfs:subClassOf obo:OBI_0200073 .

obo:SO_0001410 a rdfs:Class ;
  rdfs:label "experimental_feature" ;
  rdfs:comment "A region which is the result of some arbitrary experimental procedure. The procedure may be carried out with biological material or inside a computer." ;
  rdfs:subClassOf obo:SO_0000001 .

obo:OBCS_0000041 a rdfs:Class ;
  rdfs:label "dichotomous variable specification" ;
  rdfs:comment "A variable that has only two categories." ;
  rdfs:subClassOf obo:IAO_0000033 .

obo:OBI_0200133 a rdfs:Class ;
  rdfs:label "node out-degree calculation"@en ;
  rdfs:comment "A node quality calculation in which an input data set describing object nodes and directional relationship edges between object nodes is used to enumerate the number of unique relationships pointing out of an individual object node."@en ;
  rdfs:subClassOf obo:OBI_0200129 .

obo:STATO_0000095 a rdfs:Class ;
  rdfs:label "paired t-test"@en ;
  rdfs:comment "paired t-test is a statistical test which is specifically designed to analysis differences between paired observations in the case of studies realizing repeated measures design with only 2 repeated measurements per subject (before and after treatment for example)"@en ;
  rdfs:subClassOf obo:STATO_0000202 .

obo:OBI_0200077 a rdfs:Class ;
  rdfs:label "gating"@en ;
  rdfs:comment "Gating is a property-based vector selection with the objective of partitioning a data vector set into vector subsets based on dimension values of individual vectors (events), in which vectors represent individual physical particles (often cells) of a sample and dimension values represent light intensity qualities as measured by flow cytometry."@en ;
  rdfs:subClassOf obo:OBI_0200171 , obo:OBI_0200182 .

obo:OBCS_0000119 a rdfs:Class ;
  rdfs:label "chi-square distribution" ;
  rdfs:comment "A probability distribution that with k degrees of freedom is the distribution of a sum of the squares of k independent standard normal random variables." ;
  rdfs:subClassOf obo:OBCS_0000066 .

obo:OBI_0000707 a rdfs:Class ;
  rdfs:label "decision tree building data transformation"@en ;
  rdfs:comment "A decision tree building data transformation is a data transformation that has objective decision tree induction."@en ;
  rdfs:subClassOf obo:OBCS_0000121 .

obo:STATO_0000040 a rdfs:Class ;
  rdfs:label "MA plot"@en ;
  rdfs:comment "an MA plot is a scatter plot of the log intensity ratios M = log_2(T/R) versus the average log intensities A = log_2(T*T)/2, where T and R represent the signal intensities in the test and reference channels respectively."@en ;
  rdfs:subClassOf obo:IAO_0000184 .

obo:OBI_0200201 a rdfs:Class ;
  rdfs:label "ANOVA" ;
  rdfs:comment "A statistical hypothesis test in which the means of several groups are all equal." ;
  rdfs:subClassOf obo:OBI_0000673 .

obo:OBCS_0000051 a rdfs:Class ;
  rdfs:label "normal distribution probability density function"@en ;
  rdfs:comment "A probability density function that is for normal distribution probability" ;
  rdfs:subClassOf obo:OBCS_0000116 .

obo:OBI_0002650 a rdfs:Class ;
  rdfs:label "biopsy" ;
  rdfs:comment "A specimen collection that obtains a sample of tissue or cell from a living multicellular organism body for diagnostic purposes by means intended to be minimally invasive." ;
  rdfs:subClassOf obo:OBI_0600005 .

obo:OBI_0003073 a rdfs:Class ;
  rdfs:label "organismal body temperature measurement datum" ;
  rdfs:comment "A temperature measurement datum that is about an organism." ;
  rdfs:subClassOf obo:OBI_0003079 .

obo:OBI_0003278 a rdfs:Class ;
  rdfs:label "bacteria in pleural fluid datum" ;
  rdfs:comment "A pleural fluid microbiology datum that is about bacteria." ;
  rdfs:subClassOf obo:OBI_0003258 .

obo:OBCS_0000188 a rdfs:Class ;
  rdfs:label "data transformation in statistics"@en ;
  rdfs:comment "A data processing that applies a deterministic mathematical function to each point in a data set; that is, each data point zi is replaced with the transformed value yi = f(zi), where f is a function." ;
  rdfs:subClassOf obo:OBI_0200000 .

obo:OBI_0200114 a rdfs:Class ;
  rdfs:label "euclidean distance calculation"@en ;
  rdfs:comment "An euclidean distance calculation is a similarity calculation that attaches to each pair of real number vectors of the same dimension n the square root of the sum of the square differences between corresponding components. The smaller this number, the more similar the two vectors are considered."@en ;
  rdfs:subClassOf obo:OBI_0200113 .

obo:OBI_0003327 a rdfs:Class ;
  rdfs:label "image data set" ;
  rdfs:comment "A data set that is comprised of multidimensional structured measurements and metadata required for a morphological representation of an entity. An image data set can be the source from which an image (such as a 2D image using pixels or a 3D image using voxels) is produced." ;
  rdfs:subClassOf obo:IAO_0000100 .

obo:OBI_0000686 a rdfs:Class ;
  rdfs:label "material combination objective" ;
  rdfs:comment "is an objective to obtain an output material that contains several input materials." ;
  rdfs:subClassOf obo:OBI_0000456 .

obo:OBI_0302900 a rdfs:Class ;
  rdfs:label "group randomization"@en ;
  rdfs:comment "A group assignment which relies on chance to assign materials to a group of materials in order to avoid bias in experimental set up."@en ;
  rdfs:subClassOf obo:OBI_0600015 .

obo:OBI_0000726 a rdfs:Class ;
  rdfs:label "peak matching" ;
  rdfs:comment "Peak matching is a data transformation performed on a dataset of a graph of ordered data points (e.g. a spectrum) with the objective of pattern matching local maxima above a noise threshold" ;
  rdfs:subClassOf obo:OBI_0200000 .

obo:STATO_0000126 a rdfs:Class ;
  rdfs:label "volcano plot"@en ;
  rdfs:comment """volcano plot is a kind of scatter plot which graphs the negative log of the p-value (significance) on the y-axis versus log2 of fold-change between 2 conditions on the  x-axis. 
It is a popular method for visualizing differential occurence of variables between 2 conditions."""@en ;
  rdfs:subClassOf obo:IAO_0000184 .

obo:IAO_0000144 a rdfs:Class ;
  rdfs:label "conclusion textual entity"@en ;
  rdfs:comment "A textual entity that expresses the results of reasoning about a problem, for instance as typically found towards the end of scientific papers."@en ;
  rdfs:subClassOf obo:IAO_0000300 .

obo:OBCS_0000013 a rdfs:Class ;
  rdfs:label "test statistic" ;
  rdfs:comment "A statistic measure that is a function of the samples and considered as a numberical summary of a data-set that reduces the data to one value that can be used to perform a hypothesis test. It can be used to test a finding for statistical signifiance" ;
  rdfs:subClassOf obo:OBCS_0000220 .

obo:OBI_0200107 a rdfs:Class ;
  rdfs:label "partial least square discriminant analysis"@en ;
  rdfs:comment "PLS Discriminant Analysis (PLS-DA) is a discriminant analysis performed in order to sharpen the separation between groups of observations, by hopefully rotating PCA (Principal Components Analysis) components such that a maximum separation among classes is obtained, and to understand which variables carry the class separating information." ;
  rdfs:subClassOf obo:OBI_0200106 .

obo:IAO_8000016 a rdfs:Class ;
  rdfs:label "taxonomic bridge ontology module"@en ;
  rdfs:subClassOf obo:IAO_8000004 .

obo:OBI_0200122 a rdfs:Class ;
  rdfs:label "interquartile-range calculation"@en ;
  rdfs:comment "The interquartile range is a descriptive statistics calculation defined as the difference between the 0.75 quantile and the 0.25 quantile for a set of data."@en ;
  rdfs:subClassOf obo:OBI_0200086 .

obo:OBCS_0000185 a rdfs:Class ;
  rdfs:label "sorting"@en ;
  rdfs:comment "A data transformation process that puts the data items in a set in a certain order." ;
  rdfs:subClassOf obo:OBCS_0000188 .

obo:UBERON_8470000 a rdfs:Class ;
  rdfs:label "placental blood" ;
  rdfs:comment "Blood located in the placenta." ;
  rdfs:subClassOf obo:UBERON_0000178 .

obo:STATO_0000274 a rdfs:Class ;
  rdfs:label "receiver operational characteristics curve"@en ;
  rdfs:comment "receiver operational characteristics curve is a graphical plot which illustrates the performance of a binary classifier system as its discrimination threshold (aka cut-off point) is varied by plotting  sensitivity vs (1 − specificity)"@en ;
  rdfs:subClassOf obo:IAO_0000038 .

obo:OBCS_0000103 a rdfs:Class ;
  rdfs:label "mann-whitney U test" ;
  rdfs:comment "A non-parametric test of the null hypothesis that two populations are the same against an alternative hypothesis" ;
  rdfs:subClassOf obo:OBCS_0000236 .

obo:OBCS_0000024 a rdfs:Class ;
  rdfs:label "power calculation" ;
  rdfs:comment "A data transformation that is used to calculate the power of a statistical analysis." ;
  rdfs:subClassOf obo:OBI_0200000 .

obo:OBI_0002746 a rdfs:Class ;
  rdfs:label "induced sputum specimen" ;
  rdfs:comment "A sputum specimen that is collected from an organism following its inhalation of a nebulized salt solution." ;
  rdfs:subClassOf obo:OBI_0002508 .

obo:IAO_8000012 a rdfs:Class ;
  rdfs:label "species subset ontology module"@en ;
  rdfs:comment "A subset ontology that is crafted to either include or exclude a taxonomic grouping of species."@en ;
  rdfs:seeAlso <https://github.com/obophenotype/uberon/wiki/Taxon-constraints> ;
  rdfs:subClassOf obo:IAO_8000006 .

obo:OBI_0003331 a rdfs:Class ;
  rdfs:label "raw image data set" ;
  rdfs:comment "An image data set that encodes measurement values produced by some instrument before undergoing a data transformation." ;
  rdfs:subClassOf obo:OBI_0003327 .

obo:OBCS_0000121 a rdfs:Class ;
  rdfs:label "inferential statistical data analysis"@en ;
  rdfs:comment "A statistical data analysis that uses patterns in the sample data to draw inferences about the population represented, accounting for randomness." ;
  rdfs:subClassOf obo:OBCS_0000001 .

obo:OBCS_0000177 a rdfs:Class ;
  rdfs:label "generation of missing data"@en ;
  rdfs:comment "A planned process that generates possible values of missing data" ;
  rdfs:subClassOf obo:OBI_0000011 .

obo:STATO_0000263 a rdfs:Class ;
  rdfs:label "Galbraith plot"@en ;
  rdfs:comment """Galbraith (Radial) plot is a scatter plot which can be used in the meta-analytic context to examine the data for heterogeneity. For a fixed-effects model, the plot shows the inverse of the standard errors on the horizontal axis against the individual observed effect sizes or outcomes standardized by their corresponding standard errors on the vertical axis.
Radial plots were introduced by Rex Galbraith (1988a, 1988b, 1994).
"""@en ;
  rdfs:subClassOf obo:IAO_0000184 .

obo:UBERON_0000174 a rdfs:Class ;
  rdfs:label "excreta" ;
  rdfs:comment "A portion of organism substance that is the product of an excretion process that will be eliminated from the body. An excretion process is elimination by an organism of the waste products that arise as a result of metabolic activity." ;
  rdfs:subClassOf obo:UBERON_0000463 .

obo:OBI_0200015 a rdfs:Class ;
  rdfs:label "loess global transformation two-channel"@en ;
  rdfs:comment "A loess global transformation two-channel is a loess global transformation in the special case where the input the result of an MA transformation applied to intensities from the two channels of a two-channel assay."@en ;
  rdfs:subClassOf obo:OBI_0200023 .

obo:OBCS_0000131 a rdfs:Class ;
  rdfs:label "independent variable"@en ;
  rdfs:comment "A statistical variable that is manipulated or controlled in a scientific study to test its effect on a dependent variable(s)." ;
  rdfs:subClassOf obo:OBCS_0000038 .

obo:OBI_0200003 a rdfs:Class ;
  rdfs:label "logit-log curve fitting"@en ;
  rdfs:comment "A logit-log curve fitting is a curve fitting where first the limits y_0 an y_infty of y when x->0 and x->infinity, respectively, are estimated from the input data points (x_1, y_1), (x_2,y_2), ..., (x_n, y_n). Then a curve with equation log((y-y_0)/(y_infty-y))=a+b log(x) is obtained, where a and b are determined to optimize its fit to the input data points."@en ;
  rdfs:subClassOf obo:OBI_0200072 .

obo:OBI_0002526 a rdfs:Class ;
  rdfs:label "skin of body specimen" ;
  rdfs:comment "A specimen that is derived from skin." ;
  rdfs:subClassOf obo:OBI_0001479 .

obo:CHEBI_33696 a rdfs:Class ;
  rdfs:label "nucleic acid" ;
  rdfs:comment "A macromolecule made up of nucleotide units and hydrolysable into certain pyrimidine or purine bases (usually adenine, cytosine, guanine, thymine, uracil), D-ribose or 2-deoxy-D-ribose and phosphoric acid." ;
  rdfs:subClassOf obo:CHEBI_33839 .

obo:IAO_8000001 a rdfs:Class ;
  rdfs:label "base ontology module"@en ;
  rdfs:comment "An ontology module that comprises only of asserted axioms local to the ontology, excludes import directives, and excludes axioms or declarations from external ontologies."@en ;
  rdfs:seeAlso <https://github.com/INCATools/ontology-starter-kit/issues/50> ;
  rdfs:subClassOf obo:IAO_8000000 .

obo:OBI_0002385 a rdfs:Class ;
  rdfs:label "diagnosis of infectious disease" ;
  rdfs:comment "A diagnosis that is an assertion that a patient who is the subject of a diagnostic process has an infectious disease." ;
  rdfs:subClassOf obo:OGMS_0000073 .

obo:OBI_0001153 a rdfs:Class ;
  rdfs:label "genetic transformation objective"@en ;
  rdfs:comment "a material transformation objective aims to create genetically modified organism or cell"@en ;
  rdfs:subClassOf obo:OBI_0000456 .

obo:OBCS_0000341 a rdfs:Class ;
  rdfs:label "scenario uncertainty" ;
  rdfs:comment "Scenario uncertainty can manifest itself in various ways –  for example, (a) as a range in the outcomes of an analysis  due to different underlying assumptions, (b) as uncertainty  about which changes and developments (e.g., in driving  forces or in system characteristics) are relevant for the  outcomes of interest, or (c) as uncertainty about the levels of  these relevant changes." ;
  rdfs:subClassOf obo:OBCS_0000251 .

obo:OBI_0003076 a rdfs:Class ;
  rdfs:label "age since birth at time of visit" ;
  rdfs:comment "An age since birth measurement datum at the time of a clinical visit." ;
  rdfs:subClassOf obo:OBI_0001169 .

obo:OBI_0001908 a rdfs:Class ;
  rdfs:label "testable hypothesis" ;
  rdfs:comment "An information content entity that expresses an assertion that is intended to be tested." ;
  rdfs:subClassOf obo:IAO_0000030 .

obo:OBI_0003043 a rdfs:Class ;
  rdfs:label "urine assay" ;
  rdfs:comment "An assay that has a urine specimen as evaluant." ;
  rdfs:subClassOf obo:OBI_0000070 .

obo:OBI_0000119 a rdfs:Class ;
  rdfs:label "number of particles in subset"@en ;
  rdfs:comment "A measurement datum measuring the number of subjects in a defined subset in a flow cytometer instrument. The datum has a qualitative role"@en ;
  rdfs:subClassOf obo:IAO_0000109 .

obo:OBI_0200014 a rdfs:Class ;
  rdfs:label "split-scale transformation"@en ;
  rdfs:comment "A split-scale transformation is a data transformation which is an application of a function f described as follows to a (one dimensional) real number input. f(x)=a*x+b if x=for x>t; where log denotes a logarithmic transformation and a, b, c, d, r, t are real constants, with a, c, d, r, t positive, chosen so that f is continuous with a continuous derivative at the transition point t."@en ;
  rdfs:subClassOf obo:OBI_0200000 .

obo:IAO_0000591 a rdfs:Class ;
  rdfs:label "software method"@en ;
  rdfs:comment "A software method (also called subroutine, subprogram, procedure, method, function, or routine) is software designed to execute a specific task."@en ;
  rdfs:subClassOf obo:IAO_0000010 .

obo:OBI_0001939 a rdfs:Class ;
  rdfs:label "genome coverage" ;
  rdfs:comment "A data item that is the total number of bases in reads, divided by genome size, assumed to be the reference size (for instance of 3.10 Gb for human and 2.73 Gb for mouse) and refers to the percentage of the genome that is contained in the assembly based on size estimates; these are usually based on cytological techniques. Genome coverage of 90–95% is generally considered to be good, as most genomes contain a considerable fraction of repetitive regions that are difficult to sequence. So it is not a cause for concern if the genome coverage of an assembly is a bit less than 100%."@en ;
  rdfs:subClassOf obo:OBCS_0000233 .

obo:OBI_0600015 a rdfs:Class ;
  rdfs:label "group assignment"@en ;
  rdfs:comment "group assignment is a process which has an organism as specified input and during which a role is assigned"@en ;
  rdfs:subClassOf obo:OBI_0000011 .

obo:CHEBI_33839 a rdfs:Class ;
  rdfs:label "macromolecule" ;
  rdfs:comment "A macromolecule is a molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass." ;
  rdfs:subClassOf obo:CHEBI_23367 .

obo:IAO_0000185 a rdfs:Class ;
  rdfs:label "photograph"@en ;
  rdfs:comment "A photograph is created by projecting an image onto a photosensitive surface such as a chemically treated plate or film, CCD receptor, etc."@en ;
  rdfs:subClassOf obo:IAO_0000101 .

obo:OBI_0003269 a rdfs:Class ;
  rdfs:label "eukaryota in induced sputum datum" ;
  rdfs:comment "An induced sputum microbiology datum that is about eukaryota." ;
  rdfs:subClassOf obo:OBI_0003251 .

obo:STATO_0000177 a rdfs:Class ;
  rdfs:label "beta distribution" ;
  rdfs:comment "the beta distribution is a continuous probability distributions defined on the interval [0, 1] parametrized by two positive shape parameters, denoted by α and β, that appear as exponents of the random variable and control the shape of the distribution"@en ;
  rdfs:subClassOf obo:OBCS_0000066 .

obo:OBCS_0000158 a rdfs:Class ;
  rdfs:label "content validity"@en ;
  rdfs:comment "A test validity that determine whether it covers a representative sample of the behavior domain to be measured through systematic examination of the test content. For example, does an IQ questionnaire have items covering all areas of intelligence discussed in the scientific literature?" ;
  rdfs:subClassOf obo:OBCS_0000053 .

obo:OBCS_0000030 a rdfs:Class ;
  rdfs:label "goodness of fit" ;
  rdfs:comment "An inferential statistical data analysis used to analyze how well a statistical model fits a set of observations; measures of goodness of fit typically summarize the discrepancy between observed values and the values expected under the model in question." ;
  rdfs:subClassOf obo:OBCS_0000121 .

obo:OBCS_0000080 a rdfs:Class ;
  rdfs:label "bias" ;
  rdfs:comment "A quantitative confidence value that is a general statistical term meaning a systematic (not random) deviation from the true value" ;
  rdfs:subClassOf obo:OBI_0000071 .

obo:OBCS_0000108 a rdfs:Class ;
  rdfs:label "complex sample design" ;
  rdfs:comment "A data sampling design that is designed to generate complex samples where sample members do not have equal probability of being selected." ;
  rdfs:subClassOf obo:OBCS_0000062 .

obo:OBI_0000066 a rdfs:Class ;
  rdfs:label "investigation"@en ;
  rdfs:comment "a planned process that consists of parts: planning, study design execution, documentation and which produce conclusion(s)."@en ;
  rdfs:subClassOf obo:OBI_0000011 .

obo:UO_0000005 a rdfs:Class ;
  rdfs:label "temperature unit" ;
  rdfs:subClassOf obo:IAO_0000003 .

obo:OBI_0000208 a rdfs:Class ;
  rdfs:label "methodology testing objective"@en ;
  rdfs:comment "Methodology_testing_objective is an objective role carried out by a proposition defining the aim of the study is to examine the effect of using different methodologies."@en ;
  rdfs:subClassOf obo:IAO_0000005 .

obo:OBCS_0000035 a rdfs:Class ;
  rdfs:label "statistical model" ;
  rdfs:comment "A directive information entity that represents a mathematical relationship which relates changes in a given response to changes in one or more factors. A statistical model is a formalization of relationships between variables in the form of mathematical equations." ;
  rdfs:subClassOf obo:IAO_0000033 .

obo:OBI_0001596 a rdfs:Class ;
  rdfs:label "PDB file chain" ;
  rdfs:comment "A 3D structural organization datum that is part of a PDB file and has a specific chain identifier that identifies the entire information on a subset of the material entities." ;
  rdfs:subClassOf obo:OBI_0001155 .

obo:BFO_0000020 a rdfs:Class ;
  rdfs:label "specifically dependent continuant"@en ;
  rdfs:comment "b is a specifically dependent continuant = Def. b is a continuant & there is some independent continuant c which is not a spatial region and which is such that b s-depends_on c at every time t during the course of b’s existence. (axiom label in BFO2 Reference: [050-003])"@en ;
  rdfs:subClassOf obo:BFO_0000002 .

obo:OBI_0001525 a rdfs:Class ;
  rdfs:label "PDB file" ;
  rdfs:comment "A 3d structural organization datum capturing the results of X-ray crystallography or NMR experiment that is formatted as specified by the Protein Databank (http://www.wwpdb.org/docs.html). A PDB file can describe the structure of multiple molecules, each of which has a different chain identifier assigned." ;
  rdfs:subClassOf obo:OBI_0001155 .

obo:OBI_0200066 a rdfs:Class ;
  rdfs:label "Holm-Bonferroni family-wise error rate correction method"@en ;
  rdfs:comment "a data transformation that performs more than one hypothesis test simultaneously, a closed-test procedure, that  controls the familywise error rate for all the k hypotheses at level α in the strong sense. Objective: multiple testing correction" ;
  rdfs:subClassOf obo:OBI_0200073 .

obo:OBCS_0000169 a rdfs:Class ;
  rdfs:label "summing data values"@en ;
  rdfs:comment "A data transformation that add two or more numbers, magnitudes, quantities, or particulars as determined by or as if by the mathematical process of addition." ;
  rdfs:subClassOf obo:OBI_0200000 .

obo:OBI_0002582 a rdfs:Class ;
  rdfs:label "sequence library feature count data" ;
  rdfs:comment "The results of a sequence data feature count tabulation." ;
  rdfs:subClassOf obo:IAO_0000100 .

obo:APOLLO_SV_00000796 a rdfs:Class ;
  rdfs:label "dataset creating"@en ;
  rdfs:comment "A planned process that has a data set as its specified output."@en ;
  rdfs:subClassOf obo:OBI_0000011 .

obo:OBCS_0000240 a rdfs:Class ;
  rdfs:label "intent-to-treat analysis"@en ;
  rdfs:comment "An inferential statistical data analysis that  includes all randomized patients in the groups to which they were randomly assigned. The intent-to-treat analysis  is based on the initial treatment assignment and not on the treatment eventually received.  ITT analysis includes every subject who is randomized according to randomized treatment assignment. It ignores noncompliance, protocol deviations, withdrawal, and anything that happens after randomization." ;
  rdfs:subClassOf obo:OBCS_0000121 .

obo:OBI_0003144 a rdfs:Class ;
  rdfs:label "IC50 binding datum" ;
  rdfs:comment "A quantitative binding datum that is expressed as a half-maximal inhibitory concentration (IC50)." ;
  rdfs:subClassOf obo:OBI_0001191 , obo:OBI_0003142 .

obo:OBI_0000985 a rdfs:Class ;
  rdfs:label "growth condition intervention design" ;
  rdfs:comment "A study design in which the independent variable is the environmental condition in which the specimen is growing" ;
  rdfs:subClassOf obo:OBI_0000115 .

obo:OBI_0000991 a rdfs:Class ;
  rdfs:label "Edinburgh score" ;
  rdfs:comment "A score that measures the dominance of a person's right or left hand in everyday activities." ;
  rdfs:subClassOf obo:OBI_0000970 .

obo:OBI_0002976 a rdfs:Class ;
  rdfs:label "input protein sequence stop site" ;
  rdfs:comment "The position of the last amino acid in a protein sequence being analyzed (input protein sequence)." ;
  rdfs:subClassOf obo:OBI_0000973 .

obo:IAO_0000079 a rdfs:Class ;
  rdfs:label "density plot"@en ;
  rdfs:comment "A density plot is a report graph which is a graphical representation of data where the tint of a particular pixel corresponds to some kind of function corresponding the the amount of data points relativelly with their distance from the the pixel."@en ;
  rdfs:subClassOf obo:IAO_0000038 .

obo:OBI_0003242 a rdfs:Class ;
  rdfs:label "induced sputum microbiology assay" ;
  rdfs:comment "An organism detection assay that detects microorganisms in an induced sputum specimen." ;
  rdfs:subClassOf obo:OBI_0003234 , obo:OBI_0003498 .

obo:OBI_0000455 a rdfs:Class ;
  rdfs:label "consume data function"@en ;
  rdfs:comment "Process data function is a function that is borne by in a material entity by virtue of its structure. When realized the material entity consumes data."@en ;
  rdfs:subClassOf obo:BFO_0000034 .

obo:OBI_0003382 a rdfs:Class ;
  rdfs:label "placental blood microbiology datum" ;
  rdfs:comment "An organism detection datum that is the specified output of a placental blood microbiology assay." ;
  rdfs:subClassOf obo:OBI_0003064 , obo:OBI_0003244 .

obo:OBCS_0000352 a rdfs:Class ;
  rdfs:label "system data uncertainty" ;
  rdfs:comment "Uncertainty about the systemdata that ‘drive’ themodel and typically quantify relevant features of the reference system and its behaviour (e.g. land-use maps, data on infrastructure (roads, houses)). Uncertainty about system data is generated by a lack of knowledge of the properties (including both the deterministic and the stochastic properties) of the underlying system and deficiencies in the description of the variability that can be an inherent feature of some of the phenomena under observation. " ;
  rdfs:subClassOf obo:OBCS_0000350 .

obo:OBI_0002578 a rdfs:Class ;
  rdfs:label "adapter sequence data" ;
  rdfs:comment "Nucleotide sequences of molecules that are ligated to assay samples prior to sequencing of these samples;  these sequences are provided by assay kit manufacturers and typically used to combine sequencing of multiple samples in one assay run." ;
  rdfs:subClassOf obo:OBI_0000973 .

obo:OBCS_0000153 a rdfs:Class ;
  rdfs:label "external validity"@en ;
  rdfs:comment "An experimental validity that refers to the extent to which the (internally valid) results of a study can be held to be true for other cases, for example to different people, places or times. In other words, it is about whether findings can be validly generalized. If the same research study was conducted in those other cases, would it get the same results?" ;
  rdfs:subClassOf obo:OBCS_0000143 .

obo:OBI_0200127 a rdfs:Class ;
  rdfs:label "weighted network graph construction"@en ;
  rdfs:comment "A network graph construction in which an input data set describing objects and quantitative relationships between objects is transformed into and output representation of these objects as nodes and the quantitative relationships as weighted edges of a network graph."@en ;
  rdfs:subClassOf obo:OBI_0200126 .

obo:OBCS_0000127 a rdfs:Class ;
  rdfs:label "data collection objective"@en ;
  rdfs:comment "An objective specification where the aim is to collect data. " ;
  rdfs:subClassOf obo:IAO_0000005 .

obo:OBI_0200036 a rdfs:Class ;
  rdfs:label "Benjamini and Hochberg false discovery rate correction method"@en ;
  rdfs:comment "A data transformation process in which the Benjamini and Hochberg method sequential p-value procedure  is applied with the aim of correcting false discovery rate" ;
  rdfs:subClassOf obo:OBI_0200163 .

obo:OBI_0100060 a rdfs:Class ;
  rdfs:label "cultured cell population" ;
  rdfs:comment "A processed material comprised of a collection of cultured cells that has been continuously maintained together in culture and shares a common propagation history." ;
  rdfs:subClassOf obo:OBI_0000047 .

obo:OBCS_0000335 a rdfs:Class ;
  rdfs:label "moderate degree of certainty" ;
  rdfs:comment "definition and classification to be confirmed" ;
  rdfs:subClassOf obo:OBCS_0000251 .

obo:OBI_0002600 a rdfs:Class ;
  rdfs:label "collecting specimen with swab" ;
  rdfs:comment "A specimen collection process that uses a swab as the collection device. A swab is an absorbent material (e.g. cotton) on a rod (e.g., wooden stick)." ;
  rdfs:subClassOf obo:OBI_0000659 .

obo:OBCS_0000209 a rdfs:Class ;
  rdfs:label "multiple response variable"@en ;
  rdfs:comment "A discrete variable which can assume more than one value. A typical example is a survey questionnaire about the use of computers in research. The respondents were asked to indicate the purpose(s) for which they use computers in their research work. The respondents could score more than one category." ;
  rdfs:subClassOf obo:OBCS_0000201 .

obo:OBI_0002994 a rdfs:Class ;
  rdfs:label "presence of blood from host organism in blood meal specimen" ;
  rdfs:comment "A data item that indicates whether blood in a blood meal specimen came from a specified host organism." ;
  rdfs:subClassOf obo:IAO_0000027 .

obo:OBCS_0000199 a rdfs:Class ;
  rdfs:label "nominal data value"@en ;
  rdfs:comment "A data value that is a nominal number, ie., a number used only as a name, or to identify something (not as an actual value or position)." ;
  rdfs:subClassOf obo:OBCS_0000193 .

obo:OBI_0002988 a rdfs:Class ;
  rdfs:label "specimen collection duration" ;
  rdfs:comment "A time measurement datum that is the count of collection cycles over which a specimen collection process occurs." ;
  rdfs:subClassOf obo:IAO_0000416 .

obo:OBI_0200152 a rdfs:Class ;
  rdfs:label "polynomial degree"@en ;
  rdfs:comment "The polynomial degree is a feature of a polynomial function defined as the highest power of the polynomial's terms, where the terms of a polynomial are the individual summands with the coefficients omitted." ;
  rdfs:subClassOf obo:OBI_0200140 .

obo:OBI_0001159 a rdfs:Class ;
  rdfs:label "age since egg laying measurement datum"@en ;
  rdfs:comment "An age measurement datum that is the result of the measurement of the age of an organism since egg laying, the process of the production of egg(s) by an organism." ;
  rdfs:subClassOf obo:OBI_0001167 .

obo:STATO_0000122 a rdfs:Class ;
  rdfs:label "pedigree chart"@en ;
  rdfs:comment "a pedigree chart is a graph which plots parent child relations"@en ;
  rdfs:subClassOf obo:IAO_0000038 .

obo:OBI_0200118 a rdfs:Class ;
  rdfs:label "quantile calculation"@en ;
  rdfs:comment "A quantile calculation is a descriptive statistics calculation in which the kth quantile is the data value for which an approximate k fraction of the data is less than or equal to that value.  See http://www.stat.wvu.edu/SRS/Modules/Quantiles/quantiles.html for details."@en ;
  rdfs:subClassOf obo:OBI_0200184 .

obo:OBCS_0000363 a rdfs:Class ;
  rdfs:label "identity uncertainty" ;
  rdfs:comment "classification to be confirmed" ;
  rdfs:subClassOf obo:OBCS_0000253 .

obo:OBI_0003330 a rdfs:Class ;
  rdfs:label "magnetic resonance imaging evaluant role"@en ;
  rdfs:comment "An evaluant role that inheres in a material entity that is realized in a MR imaging assay in which MR imaging data is generated about the bearer of the evaluant role." ;
  rdfs:subClassOf obo:OBI_0000067 .

obo:RO_0000052 a rdf:Property ;
  rdfs:label "characteristic of"@en ;
  rdfs:comment "a relation between a specifically dependent continuant (the characteristic) and any other entity (the bearer), in which the characteristic depends on the bearer for its existence."@en ;
  rdfs:range <https://w3id.org/linkml/Any> .

obo:OBI_0003247 a rdfs:Class ;
  rdfs:label "urine assay datum" ;
  rdfs:comment "A data item that is the specified output of a urine assay." ;
  rdfs:subClassOf obo:IAO_0000027 .

obo:OBI_0002993 a rdfs:Class ;
  rdfs:label "prevalence of blood meal specimens from a host organism" ;
  rdfs:comment "A data item that is the frequency of blood whose source is from a specified host organism in collected blood meal specimens." ;
  rdfs:subClassOf obo:IAO_0000027 .

obo:OBCS_0000136 a rdfs:Class ;
  rdfs:label "numerical data item" ;
  rdfs:comment "A data item which consists of digits as opposed to letters of the alphabet of special characters" ;
  rdfs:subClassOf obo:IAO_0000027 .

obo:OBI_0003275 a rdfs:Class ;
  rdfs:label "bacteria in nasopharyngeal or oropharyngeal swab datum" ;
  rdfs:comment "A nasopharyngeal or oropharyngeal swab microbiology datum that is about bacteria." ;
  rdfs:subClassOf obo:OBI_0003257 .

obo:OBI_0003258 a rdfs:Class ;
  rdfs:label "pleural fluid microbiology datum" ;
  rdfs:comment "An organism detection datum that is the specified output of a pleural fluid microbiology assay." ;
  rdfs:subClassOf obo:OBI_0003064 .

obo:OBI_0500018 a rdfs:Class ;
  rdfs:label "replicate design" ;
  rdfs:comment "A replicate experimental design type is where a series of replicates are performed to evaluate reproducibility or as a pilot study to determine the appropriate number of replicates for a subsequent experiments." ;
  rdfs:subClassOf obo:OBI_0500000 .

obo:OBI_0002568 a rdfs:Class ;
  rdfs:label "sequence data feature count tabulation" ;
  rdfs:comment "The counting of features (typically, genes) within aligned sequence data, and organization of these counts into one or more tables." ;
  rdfs:subClassOf obo:APOLLO_SV_00000796 , obo:OBI_0200187 .

obo:OBI_0200141 a rdfs:Class ;
  rdfs:label "log base"@en ;
  rdfs:comment "The log base is a feature of a logarithmic function which is defined in http://en.wikipedia.org/wiki/Logarithm. Its value can be any positive real number different from 1." ;
  rdfs:subClassOf obo:OBI_0200140 .

obo:OBI_0200050 a rdfs:Class ;
  rdfs:label "dimensionality reduction"@en ;
  rdfs:comment "A dimensionality reduction is data partitioning which transforms each input m-dimensional vector (x_1, x_2, ..., x_m) into an output n-dimensional vector (y_1, y_2, ..., y_n), where n is smaller than m."@en ;
  rdfs:subClassOf obo:APOLLO_SV_00000796 , obo:OBI_0200175 .

obo:OBCS_0000046 a rdfs:Class ;
  rdfs:label "negative likelihood ratio" ;
  rdfs:comment "A likelihood ratio that is calculated by dividing 1 minus sensitivity by specificity ((1-sensitivity)/specificity)." ;
  rdfs:subClassOf obo:OBCS_0000118 .

obo:UBERON_0000072 a rdfs:Class ;
  rdfs:label "proximo-distal subdivision of respiratory tract" ;
  rdfs:comment "An section of a respiratory tract." ;
  rdfs:subClassOf obo:UBERON_0004119 , obo:UBERON_0013522 .

obo:OBCS_0000164 a rdfs:Class ;
  rdfs:label "Extraction of Differential Gene Expression software"@en ;
  rdfs:comment "A software that is used for the differential gene expression significance analysis of DNA microarray experiments for both standard and time course experiments. The outputs consist of bothe p-values and q-values." ;
  rdfs:subClassOf obo:IAO_0000010 .

obo:UBERON_0000463 a rdfs:Class ;
  rdfs:label "organism substance" ;
  rdfs:comment "Material anatomical entity in a gaseous, liquid, semisolid or solid state; produced by anatomical structures or derived from inhaled and ingested substances that have been modified by anatomical structures as they pass through the body." ;
  rdfs:subClassOf obo:UBERON_0000465 .

obo:OBI_0003264 a rdfs:Class ;
  rdfs:label "bacteria in feces datum" ;
  rdfs:comment "A feces microbiology datum that is about bacteria." ;
  rdfs:subClassOf obo:OBI_0003246 .

obo:OBI_0002396 a rdfs:Class ;
  rdfs:label "age when gave birth to first child" ;
  rdfs:comment "An age measurement datum performed on a female when her first biological child was born." ;
  rdfs:subClassOf obo:OBI_0001167 .

obo:OBI_0003040 a rdfs:Class ;
  rdfs:label "blood assay" ;
  rdfs:comment "An assay that has a blood specimen as evaulant." ;
  rdfs:subClassOf obo:OBI_0000070 .

obo:OBCS_0000368 a rdfs:Class ;
  rdfs:label "definitive certainty level" ;
  rdfs:comment "definition to be confirmed" ;
  rdfs:subClassOf obo:OBCS_0000367 .

obo:OBCS_0000297 a rdfs:Class ;
  rdfs:label "observational difficulty" ;
  rdfs:comment "definition to be confirmed" ;
  rdfs:subClassOf obo:OBCS_0000272 .

obo:OBI_0000444 a rdfs:Class ;
  rdfs:label "target of material addition role"@en ;
  rdfs:comment "A role of a material entity that is realized in an \"adding a material entity into a target\" process where the bearer of the role (the target) receives the addition of another material entity." ;
  rdfs:subClassOf obo:BFO_0000023 .

obo:OBI_0001514 a rdfs:Class ;
  rdfs:label "minimal inhibitory concentration" ;
  rdfs:comment "A scalar measurement datum that indicates the lowest concentration at which a specific compound significantly inhibits a process from occurring compared to in the absence of the compound." ;
  rdfs:subClassOf obo:IAO_0000032 .

obo:IAO_8000005 a rdfs:Class ;
  rdfs:label "import ontology module"@en ;
  rdfs:comment "A subset ontology module that is intended to be imported from another ontology."@en ;
  rdfs:seeAlso <http://robot.obolibrary.org/extract> ;
  rdfs:subClassOf obo:IAO_8000006 .

obo:OBI_0001181 a rdfs:Class ;
  rdfs:label "binding datum" ;
  rdfs:comment "A data item that states if two or more material entities have the disposition to form a complex, and if so, how strong that disposition is." ;
  rdfs:subClassOf obo:IAO_0000027 .

obo:OBCS_0000110 a rdfs:Class ;
  rdfs:label "bartlett's test" ;
  rdfs:comment "A test statistic of whether k samples are from populations with equal variances." ;
  rdfs:subClassOf obo:OBCS_0000013 .

obo:IAO_0000003 a rdfs:Class ;
  rdfs:label "measurement unit label"@en ;
  rdfs:comment "A measurement unit label is as a label that is part of a scalar measurement datum and denotes a unit of measure."@en ;
  rdfs:subClassOf obo:IAO_0000009 .

obo:OBI_0003421 a rdfs:Class ;
  rdfs:label "antigen specific antibodies in milk assay datum" ;
  rdfs:comment "An antigen specific antibodies assay datum that is the specified output of an antigen specific antibodies in milk assay." ;
  rdfs:subClassOf obo:OBI_0003365 , obo:OBI_0003417 .

obo:OBCS_0000217 a rdfs:Class ;
  rdfs:label "hierarchical tree"@en ;
  rdfs:comment "A mathematic graph that a set of objects (vertices or nodes) that are connected in a hierarchical from." ;
  rdfs:subClassOf obo:OBCS_0000216 .

obo:OBI_0200061 a rdfs:Class ;
  rdfs:label "data imputation"@en ;
  rdfs:comment "Imputation is a means of filling in missing data values from a predictive distribution of the missing values.  The predictive distribution can be created either based on a formal statistical model (i,e, a multivariate normal distribution) or an algorithm."@en ;
  rdfs:subClassOf obo:OBI_0200000 .

obo:OBCS_0000084 a rdfs:Class ;
  rdfs:label "intraclass correlation coefficient" ;
  rdfs:comment "A quantitative confidence value that is a descriptive statistic and can be used to describe how strongly units in the same group resemble each other; unlike other correlation measures it operates on data structured as groups, rather than data structured as paired observations." ;
  rdfs:subClassOf obo:OBI_0000071 .

obo:OBCS_0000092 a rdfs:Class ;
  rdfs:label "ordinal scale" ;
  rdfs:comment "A measurement scale that rankings on which data can be sorted however the size or magnitude of differences between any data points in a class is unknown, just that one ranking is greater than the other" ;
  rdfs:subClassOf obo:OBCS_0000011 .

obo:OBI_0002983 a rdfs:Class ;
  rdfs:label "altitude measurement datum" ;
  rdfs:comment "A length measurement datum between a point at sea or ground level and some point above it." ;
  rdfs:subClassOf obo:IAO_0000408 .

obo:STATO_0000174 a rdfs:Class ;
  rdfs:label "Forest plot"@en ;
  rdfs:comment "A forest plot  is a graph designed to illustrate the relative strength of treatment effects in multiple quantitative scientific studies addressing the same question."@en ;
  rdfs:subClassOf obo:IAO_0000038 .

obo:IAO_0000109 a rdfs:Class ;
  rdfs:label "measurement datum"@en ;
  rdfs:comment "A measurement datum is an information content entity that is a recording of the output of a measurement such as produced by a device."@en ;
  rdfs:subClassOf obo:IAO_0000027 .

obo:STATO_0000023 a rdfs:Class ;
  rdfs:label "studentized range distribution"@en ;
  rdfs:comment """The studentized range (q) distribution is a probability distribution used by the Tukey Honestly Significant Difference test. 

The distribution of the statistic
[x̄(k)- x̄(1)]/(s/√n)
where random samples of size n have been taken from k independent and identically distributed normal populations, with x̄(1) and x̄(k) being, respectively, the smallest and largest of the k sample means, and s2 being the pooled estimate of the common variance. This statistic is particularly used in multiple comparison tests."""@en ;
  rdfs:subClassOf obo:OBCS_0000066 .

obo:OBI_0003253 a rdfs:Class ;
  rdfs:label "cerebrospinal fluid microbiology datum" ;
  rdfs:comment "An organism detection datum that is the specified output of a cerebrospinal fluid microbiology assay." ;
  rdfs:subClassOf obo:OBI_0003064 , obo:OBI_0003252 .

obo:OBCS_0000357 a rdfs:Class ;
  rdfs:label "moral uncertainty" ;
  rdfs:comment "Moral uncertainty stems from the underlying moral issues related to action and inaction in any given case. De Marchi notes that, though similar to legal responsibility, moral guilt may occur absent legal responsibility when negative consequences might have been limited by the dissemination of prior information or more effective management for example. \"Moral uncertainty is linked to the ethical tradition of a given country be it or not enacted in legislation (juridical and societal norms, shared moral values, mores), as well as the psychological characteristics of persons in charge, their social status and professional roles\" (De Marchi, 1994). Moral uncertainty would typically be high when moral and ethical dimensions of an issue are central and participants have a range of understandings of the moral imperatives at stake." ;
  rdfs:subClassOf obo:OBCS_0000251 .

obo:OBCS_0000125 a rdfs:Class ;
  rdfs:label "exponential distribution" ;
  rdfs:comment "A continuous probability distribution that describes the time between events in a Poisson process, i.e. a process in which events occur continuously and independently at a constant average rate." ;
  rdfs:subClassOf obo:OBCS_0000066 .

obo:OBI_0200189 a rdfs:Class ;
  rdfs:label "merging objective"@en ;
  rdfs:comment "A merging objective is a data transformation objective in which the data transformation has the aim of performing a union of two or more sets."@en ;
  rdfs:subClassOf obo:OBI_0200166 .

obo:OBI_0200059 a rdfs:Class ;
  rdfs:label "mhc binding prediction"@en ;
  rdfs:comment "An MHC binding prediction takes an input of a biomaterial sequence and through an analysis of this sequence, produces as output a prediction of the likelihood that the biomaterial will bind to an MHC molecule."@en ;
  rdfs:subClassOf obo:OBI_0200187 .

obo:OBI_0003417 a rdfs:Class ;
  rdfs:label "antigen specific antibodies assay datum" ;
  rdfs:comment "A data item that is the specified output of an antigen specific antibodies assay." ;
  rdfs:subClassOf obo:IAO_0000027 .

obo:OBI_0000339 a rdfs:Class ;
  rdfs:label "planning"@en ;
  rdfs:comment "a process of creating or modifying a plan specification"@en ;
  rdfs:subClassOf obo:BFO_0000015 .

obo:OBCS_0000116 a rdfs:Class ;
  rdfs:label "probability density function" ;
  rdfs:comment "A data transformation that represents a mathematical function describing the relative likelihood of a continuous random variable to take on a value." ;
  rdfs:subClassOf obo:OBI_0200000 .

obo:OBI_0200144 a rdfs:Class ;
  rdfs:label "subgraph out-degree calculation"@en ;
  rdfs:comment "A network subgraph quality calculation in which an input data set describing subgraphs and relationship edges between subgraphs and other network objects is used to enumerate the number of unique relationships pointing out of an individual subgraph."@en ;
  rdfs:subClassOf obo:OBI_0200137 .

obo:OBI_0000653 a rdfs:Class ;
  rdfs:label "fuzzy clustering objective"@en ;
  rdfs:comment "A fuzzy clustering objective is a data transformation objective where the aim is to assign input objects (typically vectors of attributes) a probability that a point belongs to a class, where the number of class and their specifications are not known a priori."@en ;
  rdfs:subClassOf obo:OBI_0200166 .

obo:OBI_0200138 a rdfs:Class ;
  rdfs:label "subgraph degree calculation"@en ;
  rdfs:comment "A network subgraph quality calculation in which an input data set describing subgraphs and relationship edges between subgraphs and other network objects is used to enumerate the number of unique relationships of an individual subgraph."@en ;
  rdfs:subClassOf obo:OBI_0200137 .

obo:OBI_0002972 a rdfs:Class ;
  rdfs:label "endotracheal aspirate specimen" ;
  rdfs:comment "A specimen that derives from a biofilm that forms on the inner surface of an endotracheal tube while the tube is in the trachea. The specimen is collected by suction without removing the tube." ;
  rdfs:subClassOf obo:OBI_0001479 .

obo:OBI_0003234 a rdfs:Class ;
  rdfs:label "induced sputum assay" ;
  rdfs:comment "An assay that has an induced sputum specimen as evaluant." ;
  rdfs:subClassOf obo:OBI_0000070 .

obo:OBI_0000806 a rdfs:Class ;
  rdfs:label "material maintenance objective" ;
  rdfs:comment "An objective specification maintains some or all of the qualities of a material over time." ;
  rdfs:subClassOf obo:IAO_0000005 .

obo:OBI_0003256 a rdfs:Class ;
  rdfs:label "lung microbiology datum" ;
  rdfs:comment "An organism detection datum that is the specified output of a lung microbiology assay." ;
  rdfs:subClassOf obo:OBI_0003064 .

obo:OBCS_0000245 a rdfs:Class ;
  rdfs:label "Yates' chi-squared test"@en ;
  rdfs:comment "A chi square test that is used in certain situations when testing for independence in a contingency table. In some cases, Yates' correction may adjust too far, and so its current use is limited." ;
  rdfs:subClassOf obo:OBI_0200200 .

obo:IAO_0000038 a rdfs:Class ;
  rdfs:label "graph"@en ;
  rdfs:comment "A diagram that presents one or more tuples of information by mapping those tuples in to a two dimensional space in a non arbitrary way."@en ;
  rdfs:subClassOf obo:IAO_0000309 .

obo:OBCS_0000338 a rdfs:Class ;
  rdfs:label "determinism" ;
  rdfs:comment "Determinism is the ideal situation in which we know everything precisely. It is not attainable, but acts as a limiting characteristic at one end of the spectrum." ;
  rdfs:subClassOf obo:OBCS_0000251 .

obo:IAO_8000004 a rdfs:Class ;
  rdfs:label "bridge ontology module"@en ;
  rdfs:comment "An ontology module that consists entirely of axioms that connect or bridge two distinct ontology modules. For example, the Uberon-to-ZFA bridge module."@en ;
  rdfs:seeAlso <https://github.com/obophenotype/uberon/wiki/inter-anatomy-ontology-bridge-ontologies> ;
  rdfs:subClassOf obo:IAO_8000000 .

obo:OBCS_0000234 a rdfs:Class ;
  rdfs:label "eMedical record  data transformation"@en ;
  rdfs:comment "A data transformation in statistics that processes the data matrix collected from eMedical records to a form that is ready for further data analysis." ;
  rdfs:subClassOf obo:OBCS_0000188 .

obo:OBCS_0000200 a rdfs:Class ;
  rdfs:label "continuous variable"@en ;
  rdfs:comment "A continuous variable over a particular range of the real numbers is one whose value in that range must be such that, if the variable can take values a and b in that range, then it can also take any value between a and b." ;
  rdfs:subClassOf obo:OBCS_0000038 .

obo:OBI_0001214 a rdfs:Class ;
  rdfs:label "normalization testing design" ;
  rdfs:comment "A study design that tests different normalization procedures." ;
  rdfs:subClassOf obo:OBI_0500000 .

obo:OBCS_0000339 a rdfs:Class ;
  rdfs:label "statistical uncertainty" ;
  rdfs:comment "Statistical uncertainty is any uncertainty that can be  described adequately in statistical terms. Statistical uncertainty can apply to any location in the model, even to model structure uncertainties, as long as the deviation from the true value can be characterised statistically.Statistical uncertainty is what is usually referred to as‘‘uncertainty’’in the natural sciences." ;
  rdfs:subClassOf obo:OBCS_0000252 .

obo:OBI_0003243 a rdfs:Class ;
  rdfs:label "blood assay datum" ;
  rdfs:comment "A data item that is the specified output of a blood assay." ;
  rdfs:subClassOf obo:IAO_0000027 .

obo:OBI_0500013 a rdfs:Class ;
  rdfs:label "hyper graeco latin square design" ;
  rdfs:comment "PRS to do" ;
  rdfs:subClassOf obo:OBI_0500007 .

obo:OBI_0000868 a rdfs:Class ;
  rdfs:label "pattern matching objective" ;
  rdfs:comment "A pattern matching objective aims to detect the presence of the constituents of a given pattern. In contrast to pattern recognition, the pattern is rigidly specified. Patterns are typicall sequences or trees." ;
  rdfs:subClassOf obo:OBI_0200166 .

obo:OBI_0001155 a rdfs:Class ;
  rdfs:label "3D structural organization datum" ;
  rdfs:comment "A measurement datum that describes the structural orientation of a material entity in 3D space." ;
  rdfs:subClassOf obo:IAO_0000109 .

obo:OBCS_0000280 a rdfs:Class ;
  rdfs:label "diverse populations for study" ;
  rdfs:comment "definition to be confirmed" ;
  rdfs:subClassOf obo:OBCS_0000272 .

obo:OBI_0200041 a rdfs:Class ;
  rdfs:label "k-means clustering"@en ;
  rdfs:comment "A k-means clustering is a data transformation which achieves a class discovery or partitioning objective, which takes as input a collection of objects (represented as points in multidimensional space) and which partitions them into a specified number k of clusters. The algorithm attempts to find the centers of natural clusters in the data. The most common form of the algorithm starts by partitioning the input points into k initial sets, either at random or using some heuristic data. It then calculates the mean point, or centroid, of each set. It constructs a new partition by associating each point with the closest centroid. Then the centroids are recalculated for the new clusters, and the algorithm repeated by alternate applications of these two steps until convergence, which is obtained when the points no longer switch clusters (or alternatively centroids are no longer changed)."@en ;
  rdfs:subClassOf obo:APOLLO_SV_00000796 , obo:OBI_0200171 , obo:OBI_0200175 .

obo:IAO_0000102 a rdfs:Class ;
  rdfs:label "data about an ontology part"@en ;
  rdfs:comment "Data about an ontology part is a data item about a part of an ontology, for example a term"@en ;
  rdfs:subClassOf obo:IAO_0000027 .

obo:OBI_0000648 a rdfs:Class ;
  rdfs:label "clustered data set"@en ;
  rdfs:comment "A data set that is produced as the output of a class discovery data transformation and consists of a data set with assigned discovered class labels."@en ;
  rdfs:subClassOf obo:OBCS_0000123 , obo:OBCS_0000220 .

obo:OBCS_0000091 a rdfs:Class ;
  rdfs:label "nominal scale" ;
  rdfs:comment "A measurement scale that placing of data into categories, without any order or structure (see related OBI term of categorical measurement datum)." ;
  rdfs:subClassOf obo:OBCS_0000011 .

obo:OBI_0003577 a rdfs:Class ;
  rdfs:label "skin of body microbiology datum" ;
  rdfs:comment "An organism detection datum that is the specified output of a skin of body microbiology assay." ;
  rdfs:subClassOf obo:OBI_0003064 .

obo:OBCS_0000248 a rdfs:Class ;
  rdfs:label "Receiver operating characteristic curve analysis"@en ;
  rdfs:comment "A data transformation that is used to calculate a ROC curve." ;
  rdfs:subClassOf obo:APOLLO_SV_00000796 , obo:OBI_0200184 .

obo:OBI_0300311 a rdfs:Class ;
  rdfs:label "observation design" ;
  rdfs:comment "observation design is a study design in which subjects are monitored in the absence of any active intervention by experimentalists." ;
  rdfs:subClassOf obo:OBI_0500000 .

obo:OBCS_0000004 a rdfs:Class ;
  rdfs:label "gamma distribution" ;
  rdfs:comment "A continuous probability distribution that is a two-parameter family of continuous probability distributions." ;
  rdfs:subClassOf obo:OBCS_0000066 .

obo:OBI_0000235 a rdfs:Class ;
  rdfs:label "standard error"@en ;
  rdfs:comment "A quantitative confidence value which is the standard deviations of the sample in a frequency distribution, obtained by dividing the standard deviation by the total number of cases in the frequency distribution."@en ;
  rdfs:subClassOf obo:OBI_0000071 .

obo:OGMS_0000063 a rdfs:Class ;
  rdfs:label "disease course" ;
  rdfs:comment "The totality of all processes through which a given disease instance is realized."@en ;
  rdfs:subClassOf obo:BFO_0000015 .

obo:OBI_0003420 a rdfs:Class ;
  rdfs:label "antigen specific antibodies in blood assay datum" ;
  rdfs:comment "An antigen specific antibodies assay datum that is the specified output of an antigen specific antibodies in blood assay." ;
  rdfs:subClassOf obo:OBI_0003243 , obo:OBI_0003417 .

obo:OBI_0302868 a rdfs:Class ;
  rdfs:label "mean-centered data"@en ;
  rdfs:comment "a data item which has been processed by a mean centering data transformation where each output value is produced by subtracting the mean from the inout value" ;
  rdfs:subClassOf obo:OBI_0000451 .

obo:OBI_0200190 a rdfs:Class ;
  rdfs:label "clustered data visualization" ;
  rdfs:comment "A data visualization which has input of a clustered data set and produces an output of a report graph which is capable of rendering data of this type." ;
  rdfs:subClassOf obo:OBI_0200111 .

obo:OBCS_0000058 a rdfs:Class ;
  rdfs:label "sensitivity" ;
  rdfs:comment "A data item that measures the proportion of actual positives which are correctly identified as such (e.g. the percentage of sick people who are correctly identified as having the condition)." ;
  rdfs:subClassOf obo:OBCS_0000220 .

obo:OBI_0003383 a rdfs:Class ;
  rdfs:label "eukaryota in placental blood datum" ;
  rdfs:comment "A placental blood microbiology datum that is about eukaryota." ;
  rdfs:subClassOf obo:OBI_0003263 , obo:OBI_0003382 .

obo:OBCS_0000118 a rdfs:Class ;
  rdfs:label "likelihood ratio" ;
  rdfs:comment "A quantitative confidence value that expresses how many times more likely the data are under one model than the other. " ;
  rdfs:subClassOf obo:OBI_0000071 .

obo:OBCS_0000111 a rdfs:Class ;
  rdfs:label "mediating variable" ;
  rdfs:comment "A statistical variable that specifies a variable describing how, rather than when, effects will occur by accounting for the relationship between the independent and dependent variables. A mediating relationship is one in which the path relating A to C is mediated by a third variable (B)." ;
  rdfs:subClassOf obo:OBCS_0000038 .

obo:OBI_0200197 a rdfs:Class ;
  rdfs:label "spectrum analysis objective" ;
  rdfs:comment "is a data transformation objective where the aim is to analyse some aspect of spectral data by some data transformation process." ;
  rdfs:subClassOf obo:OBI_0200166 .

obo:OBI_0001364 a rdfs:Class ;
  rdfs:label "genetic alteration information"@en ;
  rdfs:comment "a genetic characteristics information that is about known changes or the lack thereof from the genetic background, including allele information, duplication, insertion, deletion, etc."@en ;
  rdfs:subClassOf obo:OBI_0001404 .

obo:OBI_0200186 a rdfs:Class ;
  rdfs:label "error correction objective"@en ;
  rdfs:comment "An error correction objective is a data transformation objective where the aim is to remove (correct for) erroneous contributions arising from the input data, or the transformation itself."@en ;
  rdfs:subClassOf obo:OBI_0200168 .

obo:OBI_0000675 a rdfs:Class ;
  rdfs:label "statistical hypothesis test objective"@en ;
  rdfs:comment "is a data transformation objective where the aim is to estimate statistical significance with the aim of proving or disproving a hypothesis by means of some data transformation." ;
  rdfs:subClassOf obo:OBI_0200166 .

obo:OBI_0003254 a rdfs:Class ;
  rdfs:label "endotracheal aspirate assay datum" ;
  rdfs:comment "An organism detection datum that is the specified output of an endotracheal aspirate assay." ;
  rdfs:subClassOf obo:IAO_0000027 .

obo:OBI_0001873 a rdfs:Class ;
  rdfs:label "number of errors"@en ;
  rdfs:comment "a data item that is the number of times that a given process failed, as an integer"@en ;
  rdfs:subClassOf obo:IAO_0000027 , obo:OBI_0001933 .

obo:OBCS_0000171 a rdfs:Class ;
  rdfs:label "data collection from online resource"@en ;
  rdfs:comment "A data collection process that is conducted  through an online process." ;
  rdfs:subClassOf obo:OBCS_0000002 .

obo:OBI_0003334 a rdfs:Class ;
  rdfs:label "reconstructed magnetic resonance image data set" ;
  rdfs:comment "An image data set that is the direct output of a raw magnetic resonance image data set reconstruction or a transformation of another MR image data set." ;
  rdfs:subClassOf obo:OBI_0003328 , obo:OBI_0003333 .

obo:UBERON_0001728 a rdfs:Class ;
  rdfs:label "nasopharynx" ;
  rdfs:comment "The section of the pharynx that lies above the soft palate." ;
  rdfs:subClassOf obo:UBERON_0000072 .

obo:OBI_0200044 a rdfs:Class ;
  rdfs:label "complete linkage hierarchical clustering"@en ;
  rdfs:comment "an agglomerative hierarchical clustering which generates successive clusters based on a distance measure, where the distance between two clusters is calculated as the maximum distance between objects from the first cluster and objects from the second cluster."@en ;
  rdfs:subClassOf obo:OBI_0200154 .

obo:UBERON_0000479 a rdfs:Class ;
  rdfs:label "tissue" ;
  rdfs:comment "Multicellular anatomical structure that consists of many cells of one or a few types, arranged in an extracellular matrix such that their long-range organisation is at least partly a repetition of their short-range organisation." ;
  rdfs:subClassOf obo:UBERON_0010000 .

obo:IAO_8000009 a rdfs:Class ;
  rdfs:label "single layer subset ontology module"@en ;
  rdfs:comment "A subset ontology that is largely comprised of a single layer or strata in an ontology class hierarchy. The purpose is typically for rolling up for visualization. The classes in the layer need not be disjoint."@en ;
  rdfs:subClassOf obo:IAO_8000006 .

obo:OBI_0400107 a rdfs:Class ;
  rdfs:label "computer" ;
  rdfs:comment "A computer is an instrument which manipulates (stores, retrieves, and processes) data according to a list of instructions." ;
  rdfs:subClassOf obo:OBI_0000968 .

obo:OBCS_0000364 a rdfs:Class ;
  rdfs:label "uncertainty about gender role" ;
  rdfs:comment "classification to be confirmed" ;
  rdfs:subClassOf obo:OBCS_0000363 .

obo:OBI_0001161 a rdfs:Class ;
  rdfs:label "age since germination measurement datum"@en ;
  rdfs:comment "An age measurement datum that is the result of the measurement of the age of an organism since germination, the process consisting of physiological and developmental changes by a seed, spore, pollen grain (microspore), or zygote that occur after release from dormancy, and encompassing events prior to and including the first visible indications of growth." ;
  rdfs:subClassOf obo:OBI_0001167 .

obo:UBERON_0001460 a rdfs:Class ;
  rdfs:label "arm" ;
  rdfs:comment "The part of the forelimb extending from the shoulder to the autopod[cjm]." ;
  rdfs:subClassOf obo:UBERON_0010000 .

obo:OBCS_0000353 a rdfs:Class ;
  rdfs:label "parameters uncertainty" ;
  rdfs:comment "definition and classification to be confirmed" ;
  rdfs:subClassOf obo:OBCS_0000252 .

obo:OBCS_0000134 a rdfs:Class ;
  rdfs:label "continuous random variable"@en ;
  rdfs:comment "A random variable which can take an infinite number of possible values." ;
  rdfs:subClassOf obo:OBCS_0000126 .

obo:OBI_0000015 a rdfs:Class ;
  rdfs:label "biological feature identification objective"@en ;
  rdfs:comment "Biological_feature_identification_objective is an objective role carried out by the proposition defining the aim of a study designed to examine or characterize a particular biological feature."@en ;
  rdfs:subClassOf obo:IAO_0000005 .

obo:OBI_0200164 a rdfs:Class ;
  rdfs:label "proportion of expected false positives correction method"@en ;
  rdfs:comment "A proportion of expected false positives correction method is a multiple testing procedure that controls the ratio of the expected value of the numbers of false positives to the expected value of the numbers of rejected hypotheses." ;
  rdfs:subClassOf obo:APOLLO_SV_00000796 , obo:OBI_0200089 .

obo:OBI_0500004 a rdfs:Class ;
  rdfs:label "n-to-1 design" ;
  rdfs:comment "N-of-1 design is a cross-over design in which the same patient is repeatedly randomised to receive either the experimental treatment or its control (Senn, 1993)." ;
  rdfs:subClassOf obo:OBI_0500003 .

obo:OBCS_0000279 a rdfs:Class ;
  rdfs:label "partially available data" ;
  rdfs:comment "definition and classification to be confirmed" ;
  rdfs:subClassOf obo:OBCS_0000272 .

obo:OBI_0001180 a rdfs:Class ;
  rdfs:label "half maximal effective concentration (EC50)" ;
  rdfs:comment "half maximal effective concentration (EC50) is a scalar measurement datum corresponding to the concentration of a compound which induces a response halfway between the baseline and maximum after some specified exposure time." ;
  rdfs:subClassOf obo:IAO_0000032 .

obo:SO_0000001 a rdfs:Class ;
  rdfs:label "region" ;
  rdfs:comment "A sequence_feature with an extent greater than zero. A nucleotide region is composed of bases and a polypeptide region is composed of amino acids." ;
  rdfs:subClassOf obo:BFO_0000031 .

obo:OBCS_0000301 a rdfs:Class ;
  rdfs:label "segmentation of uncertainty" ;
  rdfs:comment "definition to be confirmed" ;
  rdfs:subClassOf obo:OBCS_0000273 .

obo:PATO_0002201 a rdfs:Class ;
  rdfs:label "handedness" ;
  rdfs:comment "A behavioral quality inhering ina bearer by virtue of the bearer's unequal distribution of fine motor skill between its left and right hands or feet." ;
  rdfs:subClassOf obo:PATO_0001995 .

obo:OBI_0001477 a rdfs:Class ;
  rdfs:label "lowess transformation"@en ;
  rdfs:comment "A data transformation of normalizing ratio data by using a locally weighted polynomial regression (typically after a log transformation). The regression can be performed on log ratios resulting from the relation of two data sets versus the average log intensity data from the same two data sets or it can be performed on raw or log transformed values from one data set versus values from another. The goal could be to remove intensity-dependent dye-specific effects from the set of pair wise ratios. This method can be applied globally, or limited by one or more specified criteria." ;
  rdfs:subClassOf obo:OBI_0200169 .

obo:OBCS_0000182 a rdfs:Class ;
  rdfs:label "Kriging"@en ;
  rdfs:comment "A regression method of interpolation for which the interpolated values are modeled by a Gaussian process governed by prior covariances, as opposed to a piecewise-polynomial spline chosen to optimize smoothness of the fitted values." ;
  rdfs:subClassOf obo:OBI_0200102 .

obo:OBCS_0000129 a rdfs:Class ;
  rdfs:label "data collection from survey"@en ;
  rdfs:comment "A data collection by sampling process that results in a collection of data generated from an survey(s)." ;
  rdfs:subClassOf obo:OBCS_0000132 .

obo:OBCS_0000069 a rdfs:Class ;
  rdfs:label "cohen's kappa coefficient" ;
  rdfs:comment "A statistical measure of inter-rater agreement or inter-annotator agreement for qualitative (categorical) items." ;
  rdfs:subClassOf obo:OBI_0000071 .

obo:OBI_0003233 a rdfs:Class ;
  rdfs:label "endotracheal aspirate assay" ;
  rdfs:comment "An assay that has an endotracheal aspirate specimen as evaluant." ;
  rdfs:subClassOf obo:OBI_0000070 .

obo:OBCS_0000193 a rdfs:Class ;
  rdfs:label "numerical data value"@en ;
  rdfs:comment "An information content entity that refers to a number value of a data item." ;
  rdfs:subClassOf obo:IAO_0000030 .

obo:PATO_0000001 a rdfs:Class ;
  rdfs:label "quality" ;
  rdfs:comment "A dependent entity that inheres in a bearer by virtue of how the bearer is related to other entities" ;
  rdfs:subClassOf obo:BFO_0000020 .

obo:OBI_0003276 a rdfs:Class ;
  rdfs:label "eukaryota in nasopharyngeal or oropharyngeal swab datum" ;
  rdfs:comment "A nasopharyngeal or oropharyngeal swab microbiology datum that is about eukaryota." ;
  rdfs:subClassOf obo:OBI_0003257 .

obo:OBI_0001191 a rdfs:Class ;
  rdfs:label "half maximal inhibitory concentration (IC50)" ;
  rdfs:comment "Half maximal inhibitory concentration (IC50) is a scalar measurement datum that measures the effectiveness of a compound to competitively inhibit a given process, and corresponds to the concentration of the compound at which it reaches half of its maximum inhibitory effect." ;
  rdfs:subClassOf obo:IAO_0000032 .

obo:IAO_0000010 a rdfs:Class ;
  rdfs:label "software"@en ;
  rdfs:comment """Software is a plan specification composed of a series of instructions that can be 
interpreted by or directly executed by a processing unit."""@en ;
  rdfs:subClassOf obo:IAO_0000104 .

obo:OBCS_0000100 a rdfs:Class ;
  rdfs:label "type I error" ;
  rdfs:comment "A statistical error that the null hypothesis is true but has been rejected; a test result that indicates a given condition has been fulfilled, when it actually has not been fulfilled" ;
  rdfs:subClassOf obo:OBCS_0000082 .

obo:OBI_0200055 a rdfs:Class ;
  rdfs:label "dye swap merge"@en ;
  rdfs:comment "A dye swap merge is a replicate analysis which takes as input data from paired two-channel microarray assays where the sample labeled with one dye in the first assay is labeled with the other dye in the second assay and vice versa. The output for each reporter is obtained by combining its (raw or possibly pre-processed) M values in the two assays, where the M value in an assay is defined as the difference of the log intensities in the two channels. This can be used as a normalization step, when appropriate assumptions are met."@en ;
  rdfs:subClassOf obo:OBI_0200057 .

obo:OBCS_0000022 a rdfs:Class ;
  rdfs:label "multilevel model" ;
  rdfs:comment "A statistical model of parameters that vary at more than one level; a type of regression model that explicitly takes into account structured/nested data" ;
  rdfs:subClassOf obo:OBCS_0000035 .

obo:OBI_0002606 a rdfs:Class ;
  rdfs:label "nasopharyngeal swab specimen" ;
  rdfs:comment "A specimen that is collected with a swab from the surface of a nasopharynx." ;
  rdfs:subClassOf obo:OBI_0002599 .

obo:OBI_0001172 a rdfs:Class ;
  rdfs:label "dose response curve" ;
  rdfs:comment "A data item of paired values, one indicating the dose of a material, the other quantitating a measured effect at that dose. The dosing intervals are chosen so that effect values be interpolated by a plotting a curve." ;
  rdfs:subClassOf obo:IAO_0000573 .

obo:OBCS_0000081 a rdfs:Class ;
  rdfs:label "coefficient of variation" ;
  rdfs:comment "A quantitative confidence value that is the standard deviation of a data set divided by the mean of the same data set; a normalized measure of dispersion of a probability distribution" ;
  rdfs:subClassOf obo:OBI_0000071 .

obo:IAO_0000032 a rdfs:Class ;
  rdfs:label "scalar measurement datum"@en ;
  rdfs:comment "A scalar measurement datum is a measurement datum that is composed of two parts, numerals and a unit label."@en ;
  rdfs:subClassOf obo:IAO_0000109 .

obo:OBCS_0000122 a rdfs:Class ;
  rdfs:label "transformed data matrix" ;
  rdfs:comment "A data item that consists of two or more data sets that are produced as the output of a data transformation." ;
  rdfs:subClassOf obo:IAO_0000027 .

obo:OBCS_0000349 a rdfs:Class ;
  rdfs:label "model technical uncertainty" ;
  rdfs:comment "uncertainty arising from the computer implementation of the model.Model technical uncertainty is the uncertainty generated  by software or hardware errors, i.e. hidden flaws in the  technical equipment. Software errors arise from bugs in  software, design errors in algorithms and typing errors in  model source code. Hardware errors arise from bugs, such as  the bug in the early version of the Pentium processor, which gave rise to numerical error in a broad range of floating-point calculations performed on the processor." ;
  rdfs:subClassOf obo:OBCS_0000347 .

obo:OBCS_0000145 a rdfs:Class ;
  rdfs:label "contingency table"@en ;
  rdfs:comment "A data item with a specific table layout that allows visualization of the performance of an algorithm. Each column of the matrix represents the instances in a predicted class, while each row represents the instances in an actual class." ;
  rdfs:subClassOf obo:IAO_0000030 .

obo:OBI_0200137 a rdfs:Class ;
  rdfs:label "network subgraph quality calculation"@en ;
  rdfs:comment "A network analysis in which an input data set describing node objects and edge relationships between node objects is used to determine the output quality of a subgraph partition of the network."@en ;
  rdfs:subClassOf obo:OBI_0200080 .

obo:OBCS_0000215 a rdfs:Class ;
  rdfs:label "bipartite graph"@en ;
  rdfs:comment "A mathematic graph that contains a set of objects (vertices or nodes) decomposed into two disjoint sets such that no two objects within the same set are adjacent." ;
  rdfs:subClassOf obo:OBCS_0000216 .

obo:OBCS_0000167 a rdfs:Class ;
  rdfs:label "peak calling"@en ;
  rdfs:comment "An inferential statistical data analysis to identify protein-binding regions in a genome sequence from the data generated from a ChIP-sequencing or ChIP-chip experiment. When the protein is a transcription factor, the region is a transcription factor binding site (TFBS)." ;
  rdfs:subClassOf obo:OBCS_0000121 .

obo:OBCS_0000342 a rdfs:Class ;
  rdfs:label "recognized ignorance" ;
  rdfs:comment "Recognised ignorance is fundamental uncertainty about  the mechanisms and functional relationships being studied. We know neither the functional relationships nor the  statistical properties and the scientific basis for developing  scenarios is weak." ;
  rdfs:subClassOf obo:OBCS_0000251 .

obo:OBI_0000112 a rdfs:Class ;
  rdfs:label "specimen role"@en ;
  rdfs:comment "a role borne by a material entity that is gained during a specimen collection process and that can be realized by use of the specimen in an investigation"@en ;
  rdfs:subClassOf obo:BFO_0000023 .

obo:OBI_0003366 a rdfs:Class ;
  rdfs:label "organism diagnostic process"@en ;
  rdfs:comment "A drawing a conclusion based on data that involves the interpretation of data about a given organism (human, animal, or plant) and the assertion to the effect that the organism has or had a disease, disorder, or syndrome of a certain type, or none of these as output." ;
  rdfs:subClassOf obo:OBI_0000338 .

obo:OBI_0002979 a rdfs:Class ;
  rdfs:label "reference protein sequence start site" ;
  rdfs:comment "The position of the first amino acid in a reference protein sequence (sequence being used for comparison)." ;
  rdfs:subClassOf obo:OBI_0000973 .

obo:OBI_0000656 a rdfs:Class ;
  rdfs:label "data set of predicted values according to fitted curve"@en ;
  rdfs:comment "A data set which is the output of a curve fitting data transformation in which the aim is to find a curve which matches a series of data points and possibly other constraints."@en ;
  rdfs:subClassOf obo:OBCS_0000123 , obo:OBCS_0000220 .

obo:OBI_0001877 a rdfs:Class ;
  rdfs:label "random access memory"@en ;
  rdfs:comment "Random-access memory (RAM) is a form of computer data storage. A random-access device allows stored data to be accessed directly in any random order. In contrast, other data storage media such as hard disks, CDs, DVDs and magnetic tape, as well as early primary memory types such as drum memory, read and write data only in a predetermined order, consecutively, because of mechanical design limitations. Therefore, the time to access a given data location varies significantly depending on its physical location"@en ;
  rdfs:subClassOf obo:IAO_0000178 .

obo:OBCS_0000268 a rdfs:Class ;
  rdfs:label "Pluralistic fRamework of Integrated uncertainty Management and risk Analysis" ;
  rdfs:comment "A meta approach (organising  framework) to structure the process of uncertainty management" ;
  rdfs:subClassOf obo:OBCS_0000258 .

obo:OBI_0200052 a rdfs:Class ;
  rdfs:label "probabilistic algorithm"@en ;
  rdfs:comment "A probabilistic algorithm is one which involves an element of probability or randomness in the transformation of the data."@en ;
  rdfs:subClassOf obo:OBI_0200000 .

obo:OBI_0003594 a rdfs:Class ;
  rdfs:label "human leukocyte antigen mismatch count"@en ;
  rdfs:comment "A genetic characteristics information that is about the number of dissimilarities in the human leukocyte antigen gene complexes of two humans." ;
  rdfs:subClassOf obo:OBI_0001404 .

obo:BFO_0000148 a rdfs:Class ;
  rdfs:label "zero-dimensional temporal region"@en ;
  rdfs:subClassOf obo:BFO_0000008 .

obo:OBI_0002387 a rdfs:Class ;
  rdfs:label "diagnosis of hepatitis C" ;
  rdfs:comment "A diagnosis of infectious disease caused by the hepatitis C virus." ;
  rdfs:subClassOf obo:OBI_0002385 .

obo:OBCS_0000257 a rdfs:Class ;
  rdfs:label "decision making" ;
  rdfs:comment "definition to be confirmed" ;
  rdfs:subClassOf obo:OBCS_0000256 .

obo:OBI_0200029 a rdfs:Class ;
  rdfs:label "mean centering"@en ;
  rdfs:comment "A mean centering is a data transformation that takes as input an n-dimensional (real) vector, performs a mean calculation on its components, and subtracts the resulting mean from each component of the input."@en ;
  rdfs:subClassOf obo:OBI_0200169 .

obo:OBI_0000343 a rdfs:Class ;
  rdfs:label "inductive reasoning"@en ;
  rdfs:comment "a interpreting data that is used to ascribe properties or relations to types based on an observation instance (i.e., on a number of observations or experiences); or to formulate laws based on limited observations of recurring phenomenal patterns."@en ;
  rdfs:subClassOf obo:OBI_0000338 .

obo:UBERON_0006314 a rdfs:Class ;
  rdfs:label "bodily fluid" ;
  rdfs:comment "Liquid components of living organisms. includes fluids that are excreted or secreted from the body as well as body water that normally is not." ;
  rdfs:subClassOf obo:UBERON_0000463 .

obo:IAO_8000019 a rdfs:Class ;
  rdfs:label "ontology module subsetted by OWL profile"@en ;
  rdfs:subClassOf obo:IAO_8000017 .

obo:OBCS_0000323 a rdfs:Class ;
  rdfs:label "sampling error in the measurement" ;
  rdfs:comment "Sampling error is the error associated with the degree to which the sample is representative." ;
  rdfs:subClassOf obo:OBCS_0000272 .

obo:OBI_0002502 a rdfs:Class ;
  rdfs:label "cerebrospinal fluid specimen" ;
  rdfs:comment "A specimen that is derived from cerbrospinal fluid." ;
  rdfs:subClassOf obo:OBI_2000009 .

obo:OBI_0001010 a rdfs:Class ;
  rdfs:label "nucleic acid extract" ;
  rdfs:comment "An extract that is the output of an extraction process in which nucleic acid molecules are isolated from a specimen." ;
  rdfs:subClassOf obo:OBI_0000423 , obo:OBI_0000953 .

obo:OBCS_0000198 a rdfs:Class ;
  rdfs:label "undirected graph"@en ;
  rdfs:comment "A mathematic graph that a set of objects (vertices or nodes) that are connected together, where all the edges between two objects are bidirectional." ;
  rdfs:subClassOf obo:OBCS_0000216 .

obo:OBI_0000425 a rdfs:Class ;
  rdfs:label "averaging objective"@en ;
  rdfs:comment "An averaging objective is a data transformation objective where the aim is to perform mean calculations on the input of the data transformation."@en ;
  rdfs:subClassOf obo:OBI_0200166 .

obo:OBI_0200110 a rdfs:Class ;
  rdfs:label "s transformation"@en ;
  rdfs:comment "An s transformation is a data transformation obtained by applying the function S described in what follows to a (one dimensional) real number input. S(x)=T*exp(w-m)*(exp(x-w)-(p^2)*exp((w-x)/p)+p^2-1) if x>=w, S(x)=-S(w-x) otherwise; where exp denotes an exponential_transformations, 'p^' denotes the exponential transformation with base p; T, w, m, p are real constants with T, m, and p positive and w non-negative, and where w and p are related by w=2p*ln(p)(p+1) with the objective of normalization."@en ;
  rdfs:subClassOf obo:OBI_0200169 .

obo:OBI_0002145 a rdfs:Class ;
  rdfs:label "antigen specific antibodies assay" ;
  rdfs:comment "An analyte assay that measures the presence or amount of antibodies to a specified antigen." ;
  rdfs:subClassOf obo:OBI_0000443 .

obo:OBCS_0000107 a rdfs:Class ;
  rdfs:label "randomized controlled trial design" ;
  rdfs:comment "A study design in which patients are randomly assigned to two or more interventions." ;
  rdfs:subClassOf obo:OBI_0500000 .

obo:OBI_0200167 a rdfs:Class ;
  rdfs:label "data normalization objective"@en ;
  rdfs:comment """A normalization objective is a data transformation objective where the aim is to remove
systematic sources of variation to put the data on equal footing in order
to create a common base for comparisons."""@en ;
  rdfs:subClassOf obo:OBI_0200166 .

obo:OBI_0003064 a rdfs:Class ;
  rdfs:label "organism detection datum" ;
  rdfs:comment "A data item that is the specified output of an organism detection assay." ;
  rdfs:subClassOf obo:IAO_0000027 .

obo:OBI_0200126 a rdfs:Class ;
  rdfs:label "network graph construction"@en ;
  rdfs:comment "A network analysis in which an input data set describing objects and relationships between objects is transformed into an output representation of these objects as nodes and the relationships as edges of a network graph."@en ;
  rdfs:subClassOf obo:OBI_0200080 .

obo:OBI_0000997 a rdfs:Class ;
  rdfs:label "growth environment" ;
  rdfs:comment "The collection of material entities and their qualities that are located near a live organism, tissue or cell and can influence its growth." ;
  rdfs:subClassOf obo:BFO_0000040 .

obo:OBI_0002585 a rdfs:Class ;
  rdfs:label "sequence trimming" ;
  rdfs:comment "A data transformation in which subsequences of a molecular sequence are cut (removed)." ;
  rdfs:subClassOf obo:OBI_0200000 .

obo:OBI_0002975 a rdfs:Class ;
  rdfs:label "input protein sequence start site" ;
  rdfs:comment "The position of the first amino acid in a protein sequence being analyzed (input protein sequence)." ;
  rdfs:subClassOf obo:OBI_0000973 .

obo:OBI_0200175 a rdfs:Class ;
  rdfs:label "class discovery data transformation"@en ;
  rdfs:comment "A class discovery data transformation (sometimes called unsupervised classification) is a data transformation that has objective class discovery."@en ;
  rdfs:subClassOf obo:OBCS_0000121 .

obo:PATO_0000125 a rdfs:Class ;
  rdfs:label "mass" ;
  rdfs:comment "A physical quality that inheres in a bearer by virtue of the proportion of the bearer's amount of matter." ;
  rdfs:subClassOf obo:PATO_0001018 .

obo:BFO_0000003 a rdfs:Class ;
  rdfs:label "occurrent"@en ;
  rdfs:comment "An entity that has temporal parts and that happens, unfolds or develops through time."@en ;
  rdfs:subClassOf obo:BFO_0000001 .

obo:IAO_0000595 a rdfs:Class ;
  rdfs:label "software script"@en ;
  rdfs:comment "A software script is software whose instructions can be executed using a software interpreter."@en ;
  rdfs:subClassOf obo:IAO_0000010 .

obo:OBCS_0000370 a rdfs:Class ;
  rdfs:label "intermediate certainty level" ;
  rdfs:comment "definition to be confirmed" ;
  rdfs:subClassOf obo:OBCS_0000367 .

obo:STATO_0000286 a rdfs:Class ;
  rdfs:label "one tailed test"@en ;
  rdfs:comment """a one-tailed test is a statistical test which, assuming an unskewed probability distribution, allocates all of the significance level to evaluate only one hypothesis to explain a difference.
The one-tailed test provides more power to detect an effect in one direction by not testing the effect in the other direction.
one-tailed test should be preceded by two-tailed test in order to avoid missing out on detecting alternate effect explaining an observed difference."""@en ;
  rdfs:subClassOf obo:OBI_0000673 .

obo:OBI_0003356 a rdfs:Class ;
  rdfs:label "raw magnetic resonance image data set reconstruction" ;
  rdfs:comment "A process that transforms raw magnetic resonance image data from an NMR/MRI machine into a reconstructed magnetic resonance image data set." ;
  rdfs:subClassOf obo:APOLLO_SV_00000796 , obo:OBI_0003355 .

obo:OBI_0200074 a rdfs:Class ;
  rdfs:label "submatrix extraction"@en ;
  rdfs:comment "A submatrix extraction is a projection whose input is a matrix and whose output is a matrix obtained by selecting certain rows and columns from the input. (Note that, if one represents the input matrix as a vector obtained by concatenating its rows, then extracting a submatrix is equivalent to projecting this vector into that composed by the entries belonging to the rows and columns of interest from the input matrix.)"@en ;
  rdfs:subClassOf obo:OBI_0200050 .

obo:OBCS_0000039 a rdfs:Class ;
  rdfs:label "confounding variable specification" ;
  rdfs:comment "A variable specification that specifies a variable that may have a causal impact on both the independent variable and dependent variable; ignoring a confounding variable may bias empirical estimates of the causal effect of the independent variable." ;
  rdfs:subClassOf obo:IAO_0000033 .

obo:OBCS_0000312 a rdfs:Class ;
  rdfs:label "observations down-focused to smaller area" ;
  rdfs:comment "definition to be confirmed" ;
  rdfs:subClassOf obo:OBCS_0000273 .

obo:IAO_0000408 a rdfs:Class ;
  rdfs:label "length measurement datum"@en ;
  rdfs:comment "A scalar measurement datum that is the result of measurement of length quality"@en ;
  rdfs:subClassOf obo:IAO_0000032 .

obo:BFO_0000018 a rdfs:Class ;
  rdfs:label "zero-dimensional spatial region"@en ;
  rdfs:subClassOf obo:BFO_0000006 .

obo:IAO_0000300 a rdfs:Class ;
  rdfs:label "textual entity"@en ;
  rdfs:comment "A textual entity is a part of a manifestation (FRBR sense), a generically dependent continuant whose concretizations are patterns of glyphs intended to be interpreted as words, formulas, etc."@en ;
  rdfs:subClassOf obo:IAO_0000030 .

obo:OBI_0003265 a rdfs:Class ;
  rdfs:label "eukaryota in feces datum" ;
  rdfs:comment "A feces microbiology datum that is about eukaryota." ;
  rdfs:subClassOf obo:OBI_0003246 .

obo:OBCS_0000006 a rdfs:Class ;
  rdfs:label "Student's t distribution" ;
  rdfs:comment "A continuous probability distribution that is is used to estimate population parameters when the sample size is small and/or when the population variance is unknown." ;
  rdfs:subClassOf obo:OBCS_0000066 .

obo:OBI_0000701 a rdfs:Class ;
  rdfs:label "self-organizing map" ;
  rdfs:comment "A self-organizing map (SOM) is an artificial neural network with objective class discovery that uses a neighborhood function to preserve the topological properties of a dataset to produce low-dimensional (typically 2) discretized representation of the training data set. A set of artificial neurons learn to map points in an input space to coordinates in an output space. The input space can have different dimensions and topology from the output space, and the SOM will attempt to preserve these." ;
  rdfs:subClassOf obo:APOLLO_SV_00000796 , obo:OBI_0200175 .

obo:CHEBI_16991 a rdfs:Class ;
  rdfs:label "deoxyribonucleic acid" ;
  rdfs:comment "High molecular weight, linear polymers, composed of nucleotides containing deoxyribose and linked by phosphodiester bonds; DNA contain the genetic information of organisms." ;
  rdfs:subClassOf obo:CHEBI_33696 .

obo:OBI_0200071 a rdfs:Class ;
  rdfs:label "loess transformation"@en ;
  rdfs:comment "A loess transformation is a data transformation that takes as input a collection of real number pairs (x, y) and, after performing (one or more) loess fittings, utilizes the resulting curves to transform each (x, y) in the input into (x, y-f(x)) where f(x) is one of the fitted curves."@en ;
  rdfs:subClassOf obo:OBI_0200169 .

obo:OBI_0003079 a rdfs:Class ;
  rdfs:label "temperature measurement datum" ;
  rdfs:comment "A scalar measurement datum that is the result of measuring temperature." ;
  rdfs:subClassOf obo:IAO_0000032 .

obo:OBI_0200130 a rdfs:Class ;
  rdfs:label "node degree calculation"@en ;
  rdfs:comment "A node quality calculation in which an input data set describing object nodes and relationship edges between object nodes is used to enumerate the number of unique relationships of an individual object node."@en ;
  rdfs:subClassOf obo:OBI_0200129 .

obo:OBI_0200178 a rdfs:Class ;
  rdfs:label "class discovery objective"@en ;
  rdfs:comment "A class discovery objective (sometimes called unsupervised classification) is a data transformation objective where the aim is to organize input data  (typically vectors of attributes) into classes, where the number of classes and their specifications are not known a priori. Depending on usage, the class assignment can be definite or probabilistic."@en ;
  rdfs:subClassOf obo:OBI_0200166 .

obo:STATO_0000057 a rdfs:Class ;
  rdfs:label "null hypothesis"@en ;
  rdfs:comment """A null hypothesis is a statistical hypothesis that is tested for possible rejection under the assumption that it is true (usually that observations are the result of chance). The concept was introduced by R. A. Fisher.
The hypothesis contrary to the null hypothesis, usually that the observations are the result of a real effect, is known as the alternative hypothesis.[wolfram alpha]"""@en ;
  rdfs:subClassOf obo:OBI_0001908 .

obo:IAO_8000015 a rdfs:Class ;
  rdfs:label "template generated ontology module"@en ;
  rdfs:comment "An ontology module that is automatically generated from a template specification and fillers for slots in that template."@en ;
  rdfs:seeAlso <http://robot.obolibrary.org/template> , <https://github.com/dosumis/dead_simple_owl_design_patterns/> , <https://doi.org/10.1186/s13326-017-0126-0> ;
  rdfs:subClassOf obo:IAO_8000014 .

obo:OBI_0000101 a rdfs:Class ;
  rdfs:label "measured expression level"@en ;
  rdfs:comment "A measurement datum that is the outcome of the quantification of an assay for the activity of a gene, or the number of RNA transcripts."@en ;
  rdfs:subClassOf obo:IAO_0000109 .

obo:OBI_0000010 a rdfs:Class ;
  rdfs:label "fluorescent reporter intensity"@en ;
  rdfs:comment "A measurement datum that represents the output of a scanner measuring the intensity value for each fluorescent reporter."@en ;
  rdfs:subClassOf obo:IAO_0000109 .

obo:OBCS_0000212 a rdfs:Class ;
  rdfs:label "directed graph"@en ;
  rdfs:comment "A mathematic graph that a set of objects (vertices or nodes) that are connected together, where all the edges are directed from one object to another. A directed graph is sometimes called a digraph or a directed network." ;
  rdfs:subClassOf obo:OBCS_0000216 .

obo:OBI_0200063 a rdfs:Class ;
  rdfs:label "characteristic path length calculation"@en ;
  rdfs:comment "Quantifying subgraph navigability based on shortest-path length averaged over all pairs of subgraph vertices"@en ;
  rdfs:subClassOf obo:OBI_0200085 .

obo:OBI_0000749 a rdfs:Class ;
  rdfs:label "CART"@en ;
  rdfs:comment "A CART (classification and regression trees) is a data transformation method for producing a classification or regression model with a tree-based structure."@en ;
  rdfs:subClassOf obo:OBI_0000707 .

obo:IAO_0000065 a rdfs:Class ;
  rdfs:label "software interpreter"@en ;
  rdfs:comment "A software interpreter is a software application that executes some specified input software."@en ;
  rdfs:subClassOf obo:IAO_0000064 .

obo:OBCS_0000259 a rdfs:Class ;
  rdfs:label "sensitivity analysis" ;
  rdfs:comment "Study of how the uncertainty in the output of a mathematical model or system (numerical or otherwise) can be divided and allocated to different sources of uncertainty in its inputs.Conducted to understand the factors and processes that most (or least) control a model’s outputs " ;
  rdfs:subClassOf obo:OBCS_0000258 .

obo:OBCS_0000064 a rdfs:Class ;
  rdfs:label "period prevalence rate" ;
  rdfs:comment "A prevalence rate that occurs at a specific period of time." ;
  rdfs:subClassOf obo:OBCS_0000055 .

obo:OBCS_0000226 a rdfs:Class ;
  rdfs:label "numerical data set"@en ;
  rdfs:comment "A data set that is an aggregate of numerical data item. " ;
  rdfs:subClassOf obo:IAO_0000100 .

obo:UBERON_0001826 a rdfs:Class ;
  rdfs:label "nasal cavity mucosa" ;
  rdfs:comment "The mucous membrane that lines the nasal cavity[MP]." ;
  rdfs:subClassOf obo:UBERON_0000344 , obo:UBERON_0004119 , obo:UBERON_0004121 .

obo:OBCS_0000044 a rdfs:Class ;
  rdfs:label "binomial distribution" ;
  rdfs:comment "A discrete probability distribution that has the number of successes in a sequence of n independent yes/no experiments, each of which yields success with probability p. Such a success/failure experiment is also called a Bernoulli experiment or Bernoulli trial." ;
  rdfs:subClassOf obo:OBCS_0000067 .

obo:OBI_0002785 a rdfs:Class ;
  rdfs:label "aspiration specimen collection"@en ;
  rdfs:comment "Procedure using suction, usually with a thin needle and syringe, to remove bodily fluid or tissue." ;
  rdfs:subClassOf obo:OBI_0000659 .

obo:OBCS_0000327 a rdfs:Class ;
  rdfs:label "ambiguity" ;
  rdfs:comment "Ambiguity, on the other hand, is associated with one-to-many relations, that is, situations in which several alternatives are left unspecified or a desired categorization of an element is left undecided due to ignorance." ;
  rdfs:subClassOf obo:OBCS_0000253 .

obo:OBI_0001369 a rdfs:Class ;
  rdfs:label "wild type allele information"@en ;
  rdfs:comment "an allele information that is about the allele found most frequently in natural populations, or in standard laboratory stocks for a given organism."@en ;
  rdfs:subClassOf obo:OBI_0001352 .

obo:OBI_0200123 a rdfs:Class ;
  rdfs:label "skewness calculation"@en ;
  rdfs:comment "A skewness calculation is a descriptive statistics calculation defined as a parameter that describes how much a distribution (or a data set) varies from a bell-shaped curve.  See http://www.riskglossary.com/link/skewness.htm for details.  It is also known as the third central moment"@en ;
  rdfs:subClassOf obo:APOLLO_SV_00000796 , obo:OBI_0200181 .

obo:OBI_0200104 a rdfs:Class ;
  rdfs:label "principal component regression"@en ;
  rdfs:comment "The Principal Component Regression method is a regression analysis method that combines the Principal Component Analysis (PCA)spectral decomposition with an Inverse Least Squares (ILS) regression method to create a quantitative model for complex samples. Unlike quantitation methods based directly on Beer's Law which attempt to calculate the absorbtivity coefficients for the constituents of interest from a direct regression of the constituent concentrations onto the spectroscopic responses, the PCR method regresses the concentrations on the PCA scores."@en ;
  rdfs:subClassOf obo:APOLLO_SV_00000796 , obo:OBI_0200102 , obo:OBI_0200175 .

obo:OBCS_0000269 a rdfs:Class ;
  rdfs:label "Checklist for Model Quality Assistance" ;
  rdfs:comment "An instrument for internal use to assist  modellers and users of models in the process of quality control." ;
  rdfs:subClassOf obo:OBCS_0000258 .

obo:OBI_0200156 a rdfs:Class ;
  rdfs:label "data partitioning"@en ;
  rdfs:comment "Data partitioning is a data transformation with the objective of partitioning or separating input data into output subsets."@en ;
  rdfs:subClassOf obo:OBI_0200000 .

obo:OBI_0002386 a rdfs:Class ;
  rdfs:label "diagnosis of hepatitis B" ;
  rdfs:comment "A diagnosis of infectious disease caused by the hepatitis B virus." ;
  rdfs:subClassOf obo:OBI_0002385 .

obo:UO_0000002 a rdfs:Class ;
  rdfs:label "mass unit" ;
  rdfs:subClassOf obo:IAO_0000003 .

obo:OBI_0000456 a rdfs:Class ;
  rdfs:label "material transformation objective"@en ;
  rdfs:comment "an objective specifiction that creates an specific output object from input materials."@en ;
  rdfs:subClassOf obo:IAO_0000005 .

obo:OBCS_0000264 a rdfs:Class ;
  rdfs:label "Monte Carlo analysis" ;
  rdfs:comment "A broad class of computational algorithms that rely on repeated random sampling to obtain numerical results.The goal of Monte Carlo analysis is to trace out the structure of the distributions of model output that results from specified uncertainty distributions of model inputs and model parameters.  " ;
  rdfs:subClassOf obo:OBCS_0000258 .

obo:OBI_0002581 a rdfs:Class ;
  rdfs:label "merged aligned sequence data" ;
  rdfs:comment "The results of a data transformation of sequence data in which files containing aligned sequence data are merged together" ;
  rdfs:subClassOf obo:OBCS_0000233 , obo:OBI_0000973 .

obo:IAO_0000057 a rdfs:Class ;
  rdfs:label "contour plot"@en ;
  rdfs:subClassOf obo:IAO_0000038 .

obo:OBI_0000750 a rdfs:Class ;
  rdfs:label "study design independent variable"@en ;
  rdfs:comment "a directive information entity that is part of a study design. Independent variables are entities whose values are selected to determine its relationship to an observed phenomenon (the dependent variable). In such an experiment, an attempt is made to find evidence that the values of the independent variable determine the values of the dependent variable (that which is being measured). The independent variable can be changed as required, and its values do not represent a problem requiring explanation in an analysis, but are taken simply as given. The dependent variable on the other hand, usually cannot be directly controlled"@en ;
  rdfs:subClassOf obo:IAO_0000033 .

obo:OBI_0001605 a rdfs:Class ;
  rdfs:label "binding on rate measurement datum (kon)" ;
  rdfs:comment "A rate measurement datum of how quickly bound complexes form" ;
  rdfs:subClassOf obo:OBI_0001144 , obo:OBI_0001554 .

obo:OBCS_0000219 a rdfs:Class ;
  rdfs:label "derived data from descriptive statistical analysis"@en ;
  rdfs:comment "A data item that is derived from a descriptive statistical data analysis." ;
  rdfs:subClassOf obo:IAO_0000027 , obo:OBCS_0000123 , obo:OBCS_0000218 .

obo:OBCS_0000163 a rdfs:Class ;
  rdfs:label "face validity"@en ;
  rdfs:comment "A content validity that estimates whether a test appears to measure a certain criterion. It is not guaranteed that the test actually measures phenomena in that domain. When the test does not appear to be measuring what it is, it has low face validity." ;
  rdfs:subClassOf obo:OBCS_0000158 .

obo:OBI_0001028 a rdfs:Class ;
  rdfs:label "feature extraction" ;
  rdfs:comment "A planed process with objective of obtaining quantified values from an image." ;
  rdfs:subClassOf obo:OBI_0200000 .

obo:OBCS_0000253 a rdfs:Class ;
  rdfs:label "subjective uncertainty" ;
  rdfs:comment "An uncertainty that inheres in an organism (in especial human) and results from subjective cognition." ;
  rdfs:subClassOf obo:OBCS_0000251 .

obo:OBI_0100051 a rdfs:Class ;
  rdfs:label "specimen"@en ;
  rdfs:comment "A material entity that has the specimen role."@en ;
  rdfs:subClassOf obo:BFO_0000040 .

obo:OBCS_0000208 a rdfs:Class ;
  rdfs:label "preference variable"@en ;
  rdfs:comment "A preference variable is a specific discrete variable, whose value is either in a decreasing or increasing order." ;
  rdfs:subClassOf obo:OBCS_0000201 .

obo:OBI_0000451 a rdfs:Class ;
  rdfs:label "normalized data set"@en ;
  rdfs:comment "A data set that is produced as the output of a normalization data transformation."@en ;
  rdfs:subClassOf obo:OBCS_0000123 .

obo:STATO_0000159 a rdfs:Class ;
  rdfs:label "stacked bar chart" ;
  rdfs:comment "Stacked bar chart is a bar which is used to compare overall quantities across items while showing the contribution of category to the total amount. Stacked bar chart can be used  for highlighting the total as they visually aggregate all of the categories in a group while indicating a part to whole relationship. The downside is that it becomes harder to compare the sizes of the individual categories."@en ;
  rdfs:subClassOf obo:STATO_0000166 .

obo:CL_0001034 a rdfs:Class ;
  rdfs:label "cell in vitro" ;
  rdfs:comment "A cell that is maintained or propagated in a controlled artificial environment for use in an investigation." ;
  rdfs:subClassOf obo:CL_0000000 .

obo:BFO_0000140 a rdfs:Class ;
  rdfs:label "continuant fiat boundary"@en ;
  rdfs:comment "b is a continuant fiat boundary = Def. b is an immaterial entity that is of zero, one or two dimensions and does not include a spatial region as part. (axiom label in BFO2 Reference: [029-001])"@en ;
  rdfs:subClassOf obo:BFO_0000141 .

obo:GO_0050896 a rdfs:Class ;
  rdfs:label "response to stimulus" ;
  rdfs:comment "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus. The process begins with detection of the stimulus and ends with a change in state or activity or the cell or organism." ;
  rdfs:subClassOf obo:GO_0008150 .

obo:STATO_0000103 a rdfs:Class ;
  rdfs:label "multinomial distribution"@en ;
  rdfs:comment "the multinomial distribution is a probability distribution which gives the probability of any particular combination of numbers of successes for various categories defined in the context of  n independent trials each of which leads to a success for exactly one of k categories, with each category having a given fixed success probability."@en ;
  rdfs:subClassOf obo:OBCS_0000067 .

obo:OBCS_0000156 a rdfs:Class ;
  rdfs:label "convergent validity"@en ;
  rdfs:comment "A construct validity that refers to the degree to which a measure is correlated with other measures that it is theoretically predicted to correlate with." ;
  rdfs:subClassOf obo:OBCS_0000155 .

obo:OBI_0001546 a rdfs:Class ;
  rdfs:label "comparative phenotypic assessment" ;
  rdfs:comment "Interpreting data from assays that evaluate the qualities or dispositions inhering in an organism or organism part and comparing it to data from other organisms to make a conclusion about a phenotypic difference" ;
  rdfs:subClassOf obo:OBI_0000338 , obo:OBI_0001834 .

obo:OBCS_0000033 a rdfs:Class ;
  rdfs:label "loglinear analysis" ;
  rdfs:comment "A data transformation used for both hypothesis testing and model building to examine the relationship between more than two categorical variables; uses a likelihood ratio statistic that has an approximate chi-square distribution when the sample size is large." ;
  rdfs:subClassOf obo:OBI_0000673 .

obo:UBERON_0001087 a rdfs:Class ;
  rdfs:label "pleural fluid" ;
  rdfs:comment "Transudate contained in the pleural cavity." ;
  rdfs:subClassOf obo:UBERON_0007779 .

obo:OBCS_0000079 a rdfs:Class ;
  rdfs:label "type 2 error rate" ;
  rdfs:comment "A quantitative confidence value that refers to the probability of incorrectly concluding that there was no statistically significant difference in a dataset. This error often reflects insufficient power of the study." ;
  rdfs:subClassOf obo:OBI_0000071 .

obo:OBI_0000078 a rdfs:Class ;
  rdfs:label "eMedical record"@en ;
  rdfs:comment "An eMedical record is a digital document derived from a computer system used primarily for patient care in a clinical setting.  Not required to be compliant with requirements of 21 CFR Part 11."@en ;
  rdfs:subClassOf obo:IAO_0000030 .

obo:OBCS_0000331 a rdfs:Class ;
  rdfs:label "technical uncertainty" ;
  rdfs:comment "Technical uncertainty developed as a result of inadequate tools or ambiguous information about techniques. Technical uncertainty arose from difficulties with subjects, equipment, and procedures, including the lack of standard  measurement techniques. " ;
  rdfs:subClassOf obo:OBCS_0000252 .

obo:OBCS_0000290 a rdfs:Class ;
  rdfs:label "lack of funding" ;
  rdfs:comment "definition to be confirmed" ;
  rdfs:subClassOf obo:OBCS_0000272 .

obo:OBI_0600005 a rdfs:Class ;
  rdfs:label "collecting specimen from organism"@en ;
  rdfs:comment "a process with the objective to obtain a material entity that was part of an organism for potential future use in an investigation"@en ;
  rdfs:subClassOf obo:OBI_0000659 .

obo:OBI_0003279 a rdfs:Class ;
  rdfs:label "eukaryota in pleural fluid datum" ;
  rdfs:comment "A pleural fluid microbiology datum that is about eukaryota." ;
  rdfs:subClassOf obo:OBI_0003258 .

obo:OBI_0200115 a rdfs:Class ;
  rdfs:label "pearson correlation coefficient calculation"@en ;
  rdfs:comment "A pearson correlation coefficient calculation is a similarity calculation which attaches to each pair of random variables X and Y the ratio of their covariance by the product of their standard deviations. Given a series of n measurements of X and Y written as x_i and y_i where i = 1, 2, ..., n, then their Pearson correlation coefficient refers to the \"sample correlation coefficient\" and is written as the sum over i of the ratios (x_i-xbar)*(y_i-ybar)/((n-1)*s_x*s_y) where xbar and ybar are the sample means of X and Y , s_x and s_y are the sample standard deviations of X and Y. The closer the pearson correlation coefficient is to 1, the more similar the inputs are considered."@en ;
  rdfs:subClassOf obo:OBI_0200113 .

obo:OBI_0200179 a rdfs:Class ;
  rdfs:label "class prediction objective"@en ;
  rdfs:comment """A class prediction objective (sometimes called supervised classification) is a data transformation objective where the aim is to create a predictor from training data through a machine learning technique. The training data consist of pairs of objects (typically vectors of attributes) and
class labels for these objects. The resulting predictor can be used to attach class labels to any valid novel input object. Depending on usage, the prediction can be definite or probabilistic. A classification is learned from the training data and can then be tested on test data."""@en ;
  rdfs:subClassOf obo:OBI_0200166 .

obo:OBI_0000652 a rdfs:Class ;
  rdfs:label "material combination" ;
  rdfs:comment "is a material processing with the objective to combine two or more material entities as input into a single material entity as output." ;
  rdfs:subClassOf obo:OBI_0000094 .

obo:OBI_0200145 a rdfs:Class ;
  rdfs:label "intra subgraph connectivity calculation"@en ;
  rdfs:comment "A network subgraph quality calculation in which an input data set describing internal nodes, edges and node degrees is used to determine the average node degree within the subgraph."@en ;
  rdfs:subClassOf obo:OBI_0200137 .

obo:UBERON_0004119 a rdfs:Class ;
  rdfs:label "endoderm-derived structure" ;
  rdfs:comment "An anatomical structure that develops (entirely or partially) from the endoderm." ;
  rdfs:subClassOf obo:UBERON_0000061 .

obo:OBI_0003380 a rdfs:Class ;
  rdfs:label "placental blood specimen" ;
  rdfs:comment "A specimen that is derived from placental blood." ;
  rdfs:subClassOf obo:OBI_2000009 .

obo:OBI_0200131 a rdfs:Class ;
  rdfs:label "quantitative node degree calculation"@en ;
  rdfs:comment "A node quality calculation in which an input data set describing object nodes and quantitative relationship edges between object nodes is used to sum all of the quantitative relationships of an individual object node."@en ;
  rdfs:subClassOf obo:OBI_0200129 .

obo:OBI_0200030 a rdfs:Class ;
  rdfs:label "median centering"@en ;
  rdfs:comment "A median centering is a data transformation that takes as input an n-dimensional (real) vector, performs a median calculation on its components, and subtracts the resulting median from each component of the input."@en ;
  rdfs:subClassOf obo:OBI_0200169 .

obo:OBI_0000392 a rdfs:Class ;
  rdfs:label "information processor function"@en ;
  rdfs:comment "An information processor function is a function that converts information from one form to another, by a lossless process or an extraction process."@en ;
  rdfs:subClassOf obo:BFO_0000034 .

obo:IAO_8000020 a rdfs:Class ;
  rdfs:label "EL++ ontology module"@en ;
  rdfs:subClassOf obo:IAO_8000019 .

obo:OBCS_0000316 a rdfs:Class ;
  rdfs:label "limited understanding" ;
  rdfs:comment "definition to be confirmed" ;
  rdfs:subClassOf obo:OBCS_0000272 .

obo:OBCS_0000286 a rdfs:Class ;
  rdfs:label "delayed information" ;
  rdfs:comment "definition and classification to be confirmed" ;
  rdfs:subClassOf obo:OBCS_0000272 .

obo:IAO_0000140 a rdfs:Class ;
  rdfs:label "setting datum"@en ;
  rdfs:comment "A settings datum is a datum that denotes some configuration of an instrument."@en ;
  rdfs:subClassOf obo:IAO_0000027 .

obo:OBI_0000257 a rdfs:Class ;
  rdfs:label "DNA extraction"@en ;
  rdfs:comment "A DNA extraction is a nucleic acid extraction where the desired output material is DNA."@en ;
  rdfs:subClassOf obo:OBI_0666667 .

obo:OBCS_0000258 a rdfs:Class ;
  rdfs:label "uncertainty analysis" ;
  rdfs:comment "definition to be confirmed" ;
  rdfs:subClassOf obo:OBI_0000011 .

obo:OBI_0003084 a rdfs:Class ;
  rdfs:label "specimen collection time post infection" ;
  rdfs:comment "A specimen collection time measurement datum that is the measure of a time when specimens are collected after an infection starts." ;
  rdfs:subClassOf obo:OBI_0001619 .

obo:OBCS_0000098 a rdfs:Class ;
  rdfs:label "random effect" ;
  rdfs:comment "A statistical effect that is associated with input variables chosen at random from a population having a large or infinite number of possible values." ;
  rdfs:subClassOf obo:OBCS_0000037 .

obo:OBI_0000319 a rdfs:Class ;
  rdfs:label "material to be added role"@en ;
  rdfs:comment "A role of a material entity that is realized in an \"adding a material entity into a target\" process where the bearer of the role is added into another material entity (the target)."@en ;
  rdfs:subClassOf obo:BFO_0000023 .

obo:OBI_0200134 a rdfs:Class ;
  rdfs:label "node shortest path identification"@en ;
  rdfs:comment "A node quality calculation in which a path describing the shortest path needed to transverse through connected nodes and edges to arrive at a specific target node in the network."@en ;
  rdfs:subClassOf obo:OBI_0200129 .

obo:OBI_0003268 a rdfs:Class ;
  rdfs:label "bacteria in induced sputum datum" ;
  rdfs:comment "An induced sputum microbiology datum that is about bacteria." ;
  rdfs:subClassOf obo:OBI_0003251 .

obo:OBI_0200078 a rdfs:Class ;
  rdfs:label "descriptive statistical calculation objective"@en ;
  rdfs:comment "A descriptive statistical calculation objective is a data transformation objective which concerns any calculation intended to describe a feature of a data set, for example, its center or its variability."@en ;
  rdfs:subClassOf obo:OBI_0200166 .

obo:OBI_0003075 a rdfs:Class ;
  rdfs:label "age since birth at time of enrollment" ;
  rdfs:comment "An age since birth measurement datum at the time of subject enrollment." ;
  rdfs:subClassOf obo:OBI_0001169 .

obo:IAO_0000594 a rdfs:Class ;
  rdfs:label "software application"@en ;
  rdfs:comment "A software application is software that can be directly executed by some processing unit."@en ;
  rdfs:subClassOf obo:IAO_0000010 .

obo:OBI_0001508 a rdfs:Class ;
  rdfs:label "sampling time measurement datum"@en ;
  rdfs:comment "A time measurement datum when an observation is made or a sample is taken from a material as measured from some reference point." ;
  rdfs:subClassOf obo:IAO_0000416 .

obo:OBCS_0000371 a rdfs:Class ;
  rdfs:label "highest uncertainty degree" ;
  rdfs:comment "definition to be confirmed" ;
  rdfs:subClassOf obo:OBCS_0000367 .

obo:BFO_0000031 a rdfs:Class ;
  rdfs:label "generically dependent continuant"@en ;
  rdfs:comment "b is a generically dependent continuant = Def. b is a continuant that g-depends_on one or more other entities. (axiom label in BFO2 Reference: [074-001])"@en ;
  rdfs:subClassOf obo:BFO_0000002 .

obo:OBCS_0000309 a rdfs:Class ;
  rdfs:label "utilitarian emphasis on practical result" ;
  rdfs:comment "definition to be confirmed" ;
  rdfs:subClassOf obo:OBCS_0000273 .

obo:OBI_0200082 a rdfs:Class ;
  rdfs:label "longitudinal data analysis"@en ;
  rdfs:comment "Longitudinal analysis is a data transformation used to perform repeated observations of the same items over long periods of time."@en ;
  rdfs:subClassOf obo:OBI_0200000 .

obo:OBI_0000067 a rdfs:Class ;
  rdfs:label "evaluant role"@en ;
  rdfs:comment "a role that inheres in a material entity that is realized in an assay in which data is generated about the bearer of the evaluant role"@en ;
  rdfs:subClassOf obo:BFO_0000023 .

obo:OBCS_0000068 a rdfs:Class ;
  rdfs:label "frequency distribution" ;
  rdfs:comment "A tabular summary of a set of data showing the number of items in each of several non-overlapping classes or groupings" ;
  rdfs:subClassOf obo:OBCS_0000010 .

obo:OBI_0002780 a rdfs:Class ;
  rdfs:label "nasal aspirate specimen" ;
  rdfs:comment "A specimen that is collected with a suctioning tube from the nasal cavity." ;
  rdfs:subClassOf obo:OBI_0100051 .

obo:OBI_0000650 a rdfs:Class ;
  rdfs:label "differential expression analysis data transformation"@en ;
  rdfs:comment "A differential expression analysis data transformation is a data transformation that has an objective of differential expression analysis.  Frequently this data transformation involves summarizing or otherwise aggregating signals from various samples categorized into groups, and calculating measures of group differences from these aggregated signals."@en ;
  rdfs:subClassOf obo:OBI_0200000 .

obo:OBI_0001581 a rdfs:Class ;
  rdfs:label "equilibrium dissociation constant (KD) approximated by EC50" ;
  rdfs:comment "A measurement of an EC50 value under specific assay conditions approximates KD, namely the binding reaction is at an equilibrium,  and the concentration of the receptor must be much less than the KD for the ligand." ;
  rdfs:subClassOf obo:OBI_0001536 , obo:OBI_0003143 .

obo:OBI_0002137 a rdfs:Class ;
  rdfs:label "RNA Integrity Number value specification"@en ;
  rdfs:comment "A value specification that specifies the value of the RNA Integrity Number as a real value between 1 (most degraded) and 10 (most intact)." ;
  rdfs:subClassOf obo:OBI_0001933 .

obo:BFO_0000147 a rdfs:Class ;
  rdfs:label "zero-dimensional continuant fiat boundary"@en ;
  rdfs:subClassOf obo:BFO_0000140 .

obo:OBI_0002770 a rdfs:Class ;
  rdfs:label "partial karyotype information"@en ;
  rdfs:comment "A karyotype information that is about the structural variation of partial genome rather than whole genome."@en ;
  rdfs:subClassOf obo:OBI_0002769 .

obo:OBI_0200060 a rdfs:Class ;
  rdfs:label "t cell epitope prediction"@en ;
  rdfs:comment "A T cell epitope prediction takes as input an antigen sequence, and through an analysis of this sequence, produces as output a prediction of the likelihood the biomaterial is a T cell epitope."@en ;
  rdfs:subClassOf obo:OBI_0200187 .

obo:OBCS_0000152 a rdfs:Class ;
  rdfs:label "internal validity"@en ;
  rdfs:comment "An experimental validity that refers to the degree to which conclusions about causal relationships can be made (e.g. cause and effect), based on the measures used, the research setting, and the whole research design." ;
  rdfs:subClassOf obo:OBCS_0000143 .

obo:OBI_0001575 a rdfs:Class ;
  rdfs:label "assigning gene property based on phenotypic assessment" ;
  rdfs:comment "Interpreting data from assays that evaluate the qualities or dispositions inhering in an organism or organism part and comparing it to data from other organisms that have a defined genetic difference, and assigning a property to the product of the targeted gene as a result." ;
  rdfs:subClassOf obo:OBI_0000338 .

obo:OBI_0000679 a rdfs:Class ;
  rdfs:label "average value"@en ;
  rdfs:comment "A  data item that is produced as the output of an averaging data transformation and represents the average value of the input data."@en ;
  rdfs:subClassOf obo:OBCS_0000219 , obo:OBI_0000649 .

obo:OBCS_0000241 a rdfs:Class ;
  rdfs:label "Kolmogorov–Smirnov test"@en ;
  rdfs:comment "A non-parametric test of the equality of continuous, one-dimensional probability distributions that can be used to compare a sample with a reference probability distribution (one-sample K–S test), or to compare two samples (two-sample K–S test). The distributions considered under the null hypothesis are continuous distributions but are otherwise unrestricted." ;
  rdfs:subClassOf obo:OBCS_0000236 .

obo:OBI_0200033 a rdfs:Class ;
  rdfs:label "leave one out cross validation method"@en ;
  rdfs:comment "is a data transformation :  leave-one-out cross-validation (LOOCV) involves using a single observation from the original sample as the validation data, and the remaining observations as the training data. This is repeated such that each observation in the sample is used once as the validation data" ;
  rdfs:subClassOf obo:OBI_0000792 .

<https://w3id.org/linkml/Any> a rdfs:Class ;
  rdfs:comment "An unconstrained type or object" .

obo:OBCS_0000115 a rdfs:Class ;
  rdfs:label "mixed model" ;
  rdfs:comment "A statistical model containing both fixed effects and random effects, that is mixed effects;" ;
  rdfs:subClassOf obo:OBCS_0000035 .

obo:OBCS_0000295 a rdfs:Class ;
  rdfs:label "operative complication (experimental)" ;
  rdfs:comment "definition to be confirmed" ;
  rdfs:subClassOf obo:OBCS_0000272 .

obo:IAO_0000005 a rdfs:Class ;
  rdfs:label "objective specification"@en ;
  rdfs:comment "A directive information entity that describes an intended process endpoint. When part of a plan specification the concretization is realized in a planned process in which the bearer tries to effect the world so that the process endpoint is achieved."@en ;
  rdfs:subClassOf obo:IAO_0000033 .

obo:OBCS_0000204 a rdfs:Class ;
  rdfs:label "ratio-scale variable"@en ;
  rdfs:comment "A continuous variable that is a continuous positive measurement on a nonlinear scale" ;
  rdfs:subClassOf obo:OBCS_0000200 .

obo:OBI_0000071 a rdfs:Class ;
  rdfs:label "quantitative confidence value"@en ;
  rdfs:comment "A data item which is used to indicate the degree of uncertainty about a measurement."@en ;
  rdfs:subClassOf obo:OBCS_0000220 .

obo:OBCS_0000230 a rdfs:Class ;
  rdfs:label "data collection from eMedical record"@en ;
  rdfs:comment "A data collection process that results in a collection of data generated from eMedical record(s)." ;
  rdfs:subClassOf obo:OBCS_0000002 .

obo:OBI_0200108 a rdfs:Class ;
  rdfs:label "eh transformation"@en ;
  rdfs:comment "An eh transformation is a data transformation obtained by applying the function EH described in what follows to a (one dimensional) real number input. EH(x)=exp(x*d/r)+b*(d/r)*x-1, if x>=0, and EH(x)=-exp(-x*d/r)+b*(d/r)*x+1, otherwise. Here exp denotes an exponential transformation and b, d, r are positive real constants with the objective of normalization."@en ;
  rdfs:subClassOf obo:OBI_0200169 .

obo:OBI_0200000 a rdfs:Class ;
  rdfs:label "data transformation"@en ;
  rdfs:comment "A planned process that produces output data from input data."@en ;
  rdfs:subClassOf obo:OBI_0000011 .

obo:OBI_0000811 a rdfs:Class ;
  rdfs:label "primary structure of DNA macromolecule" ;
  rdfs:comment "a quality of a DNA molecule that inheres in its bearer due to the order of its DNA nucleotide residues." ;
  rdfs:subClassOf obo:SO_0000001 .

obo:OBI_0000791 a rdfs:Class ;
  rdfs:label "multiple testing correction objective" ;
  rdfs:comment "A multiple testing correction objectives is a data transformation objective where the aim is to correct for a set of statistical inferences considered simultaneously" ;
  rdfs:subClassOf obo:OBI_0200186 .

obo:IAO_8000008 a rdfs:Class ;
  rdfs:label "analysis subset ontology module"@en ;
  rdfs:comment "An ontology module that is intended for usage in analysis or discovery applications."@en ;
  rdfs:subClassOf obo:IAO_8000006 .

obo:OBI_0000727 a rdfs:Class ;
  rdfs:label "k-nearest neighbors"@en ;
  rdfs:comment "A k-nearest neighbors is a data transformation which achieves a class discovery or partitioning objective, in which an input data object with vector y is assigned to a class label based upon the k closest training data set points to y; where k is the largest value that class label is assigned."@en ;
  rdfs:subClassOf obo:APOLLO_SV_00000796 , obo:OBI_0200171 , obo:OBI_0200175 .

obo:OBI_0200045 a rdfs:Class ;
  rdfs:label "single linkage hierarchical clustering"@en ;
  rdfs:comment "A single linkage hierarchical clustering is an agglomerative hierarchical clustering which generates successive clusters based on a distance measure, where the distance between two clusters is calculated as the minimum distance between objects from the first cluster and objects from the second cluster."@en ;
  rdfs:subClassOf obo:OBI_0200154 .

obo:OBI_0001169 a rdfs:Class ;
  rdfs:label "age since birth measurement datum"@en ;
  rdfs:comment "An age measurement datum that is the result of the measurement of the age of an organism since birth, the process of emergence and separation of offspring from the mother." ;
  rdfs:subClassOf obo:OBI_0001167 .

obo:OBI_0000659 a rdfs:Class ;
  rdfs:label "specimen collection process" ;
  rdfs:comment "A planned process with the objective of collecting a specimen." ;
  rdfs:subClassOf obo:OBI_0000011 .

obo:OBI_0200153 a rdfs:Class ;
  rdfs:label "number of variables"@en ;
  rdfs:comment "The number of variables is a feature of any function (including polynomial functions) with domain contained in an n-dimensional vector space and is defined as n, the dimension of such space." ;
  rdfs:subClassOf obo:OBI_0200140 .

obo:OBCS_0000326 a rdfs:Class ;
  rdfs:label "vagueness" ;
  rdfs:comment "vagueness is associated with the lack of precise or sharp distinctions or boundaries" ;
  rdfs:subClassOf obo:OBCS_0000251 .

obo:BFO_0000144 a rdfs:Class ;
  rdfs:label "process profile"@en ;
  rdfs:comment "b is a process_profile =Def. there is some process c such that b process_profile_of c (axiom label in BFO2 Reference: [093-002])"@en ;
  rdfs:subClassOf obo:BFO_0000015 .

obo:IAO_0000179 a rdfs:Class ;
  rdfs:label "histogram"@en ;
  rdfs:comment """A histogram is a report graph which is a statistical description of a
distribution in terms of occurrence frequencies of different event classes."""@en ;
  rdfs:subClassOf obo:IAO_0000038 .

obo:STATO_0000202 a rdfs:Class ;
  rdfs:label "within subject comparison statistical test"@en ;
  rdfs:comment "within subject comparison statistical test is a kind of statistical test which evaluates if a change occurs within one experimental unit over time following a treatment or an event"@en ;
  rdfs:subClassOf obo:OBI_0000673 .

obo:OBI_0200119 a rdfs:Class ;
  rdfs:label "median calculation"@en ;
  rdfs:comment "A median calculation is a  descriptive statistics calculation in which the midpoint of the data set (the 0.5 quantile) is calculated.  First, the observations are sorted in increasing order.  For an odd number of observations, the median is the middle value of the sorted data.  For an even number of observations, the median is the average of the two middle values."@en ;
  rdfs:subClassOf obo:APOLLO_SV_00000796 , obo:OBI_0200181 .

obo:OBI_0000668 a rdfs:Class ;
  rdfs:label "error correction data transformation"@en ;
  rdfs:comment "An error correction data transformation is a data transformation that has the objective of error correction, where the aim is to remove (correct for) erroneous contributions from the input to the data transformation."@en ;
  rdfs:subClassOf obo:OBI_0200000 .

obo:OBI_0500002 a rdfs:Class ;
  rdfs:label "repeated measure design" ;
  rdfs:comment "a study design which use the same individuals and exposure them to a set of conditions. The effect of order and practice can be confounding factor in such designs" ;
  rdfs:subClassOf obo:OBI_0000115 .

obo:OBCS_0000057 a rdfs:Class ;
  rdfs:label "reliability" ;
  rdfs:comment "A data item that refers to the extent to which repeated measurements of a relatively stable phenomenon fall closely to each other." ;
  rdfs:subClassOf obo:OBCS_0000220 .

obo:OBI_0500007 a rdfs:Class ;
  rdfs:label "randomized complete block design" ;
  rdfs:comment "A randomized complete block design is_a study design which assigns randomly treatments to block. The number of units per block equals the number of treatment so each block receives each treatment exactly once (hence the qualifier 'complete'). The design was originally devised from field trials used in agronomy and agriculture. The analysis assumes that there is no interaction between block and treatment. The method was then used in other settings So The randomised complete block design is a design in which the subjects are matched according to a variable which the experimenter wishes to control. The subjects are put into groups (blocks) of the same size as the number of treatments. The members of each block are then randomly assigned to different treatment groups." ;
  rdfs:subClassOf obo:OBI_0000115 .

obo:OBI_0001358 a rdfs:Class ;
  rdfs:label "post-transcriptional modification design" ;
  rdfs:comment "A study design in which a modification of the transcriptome, proteome (not genome) is made, for example RNAi, antibody targeting." ;
  rdfs:subClassOf obo:OBI_0000115 .

obo:OBI_0000086 a rdfs:Class ;
  rdfs:label "reagent role"@en ;
  rdfs:comment "A role inhering in a biological or chemical entity that is intended to be applied in a scientific technique to participate (or have molecular components that participate) in a chemical reaction that facilitates the generation of data about some entity distinct from the bearer, or the generation of some specified material output distinct from the bearer."@en ;
  rdfs:subClassOf obo:BFO_0000023 .

obo:OBI_0000873 a rdfs:Class ;
  rdfs:label "pre-mortem specimen" ;
  rdfs:comment "a specimen that was taken from a live organism" ;
  rdfs:subClassOf obo:OBI_0001506 .

obo:OBI_0000969 a rdfs:Class ;
  rdfs:label "dose specification" ;
  rdfs:comment "a directive information entity that describes the dose that will be administered to a target" ;
  rdfs:subClassOf obo:IAO_0000033 .

obo:IAO_0000400 a rdfs:Class ;
  rdfs:label "cartesian spatial coordinate datum"@en ;
  rdfs:comment "A cartesian spatial coordinate datum is a representation of a point in a spatial region, in which equal changes in the magnitude of a coordinate value denote length qualities with the same magnitude"@en ;
  rdfs:subClassOf obo:IAO_0000027 .

obo:OBI_0200022 a rdfs:Class ;
  rdfs:label "variance stabilizing transformation"@en ;
  rdfs:comment "A variance stabilizing transformation is a data transformation, described in PMID 12169536, whose input is a matrix [y_ik] and whose output is a matrix obtained by applying formula (6) in this paper. One of the goals is to obtain an output matrix whose rows have equal variances. The method relies on various assumptions described in the paper."@en ;
  rdfs:subClassOf obo:OBI_0200169 .

obo:OBI_0200018 a rdfs:Class ;
  rdfs:label "loess group transformation one-channel"@en ;
  rdfs:comment "A loess group transformation one-channel is a loess group transformation in the special case where the input is the result of an MA transformation applied to intensities from two related one-channel assays."@en ;
  rdfs:subClassOf obo:OBI_0200024 .

obo:OBCS_0000130 a rdfs:Class ;
  rdfs:label "data collection from literature"@en ;
  rdfs:comment "A data collection process that results in a collection of data from the literature." ;
  rdfs:subClassOf obo:OBCS_0000002 .

obo:OBI_0001396 a rdfs:Class ;
  rdfs:label "stimulus or stress design" ;
  rdfs:comment "A study design in which the response of an organism(s) to the stress or stimulus is studied, e.g. osmotic stress, heat shock, radiation exposure, behavioral treatment etc." ;
  rdfs:subClassOf obo:OBI_0000115 .

obo:OBCS_0000011 a rdfs:Class ;
  rdfs:label "measurement scale" ;
  rdfs:comment "An information content entity that represents a type of scale on which a variable is measured, including nominal, ordinal, interval, ratio." ;
  rdfs:subClassOf obo:IAO_0000030 .

obo:IAO_0000027 a rdfs:Class ;
  rdfs:label "data item"@en ;
  rdfs:comment "An information content entity that is intended to be a truthful statement about something (modulo, e.g., measurement precision or other systematic errors) and is constructed/acquired by a method which reliably tends to produce (approximately) truthful statements."@en ;
  rdfs:subClassOf obo:IAO_0000030 .

obo:OBI_0200093 a rdfs:Class ;
  rdfs:label "polynomial transformation"@en ;
  rdfs:comment "A polynomial transformation is a data transformation that is obtained through a polynomial, where a polynomial is a mathematical expression involving a sum of powers in one or more variables multiplied by coefficients (e.g. see http://mathworld.wolfram.com/Polynomial.html). The number of variables and the degree are properties of a polynomial. The degree of a polynomial is the highest power of its terms, where the terms of a polynomial are the individual summands with the coefficients omitted."@en ;
  rdfs:subClassOf obo:OBCS_0000188 .

obo:OBI_0002480 a rdfs:Class ;
  rdfs:label "sequencing library input quantity measurement datum"@en ;
  rdfs:comment "A scalar measurement datum that indicates the amount of sequencing library used as input for a sequencer."@en ;
  rdfs:subClassOf obo:IAO_0000032 .

obo:OBI_0000634 a rdfs:Class ;
  rdfs:label "DNA methylation profiling assay" ;
  rdfs:comment "An assay that measures the state of methylation of DNA molecules using genomic DNA collected from a material entity using a range of techniques and instrument such as DNA sequencers and often relying on treatment with bisulfites to ensure cytosine conversion." ;
  rdfs:subClassOf obo:OBI_0002020 .

obo:BFO_0000024 a rdfs:Class ;
  rdfs:label "fiat object part"@en ;
  rdfs:subClassOf obo:BFO_0000040 .

obo:OBI_0200011 a rdfs:Class ;
  rdfs:label "logical transformation"@en ;
  rdfs:comment "A logical transformation is a data transformation that, for each (one dimensional) real number input x, outputs an approximation (found, e.g. with the Newton's method) to a solution y of the equation S(y)-x=0, where S denotes an s transformation."@en ;
  rdfs:subClassOf obo:OBI_0200169 .

obo:OBCS_0000305 a rdfs:Class ;
  rdfs:label "shotgun treatment" ;
  rdfs:comment "definition to be confirmed" ;
  rdfs:subClassOf obo:OBCS_0000273 .

obo:UBERON_0000062 a rdfs:Class ;
  rdfs:label "organ" ;
  rdfs:comment "Anatomical structure that performs a specific function or group of functions [WP]." ;
  rdfs:subClassOf obo:UBERON_0010000 .

obo:OBCS_0000275 a rdfs:Class ;
  rdfs:label "multiple effects from single cause" ;
  rdfs:comment "definition to be confirmed" ;
  rdfs:subClassOf obo:OBCS_0000272 .

obo:IAO_0000310 a rdfs:Class ;
  rdfs:label "document"@en ;
  rdfs:comment "A collection of information content entities intended to be understood together as a whole"@en ;
  rdfs:subClassOf obo:IAO_0000030 .

obo:OBI_0200098 a rdfs:Class ;
  rdfs:label "soft independent modeling of class analogy analysis"@en ;
  rdfs:comment "Soft independent modeling by class analogy (SIMCA) is a descriptive statistics method for supervised classification of data. The method requires a training data set consisting of samples (or objects) with a set of attributes and their class membership. The term soft refers to the fact the classifier can identify samples as belonging to multiple classes and not necessarily producing a classification of samples into non-overlapping classes."@en ;
  rdfs:subClassOf obo:OBI_0200169 .

obo:OBI_0000175 a rdfs:Class ;
  rdfs:label "p-value"@en ;
  rdfs:comment "A quantitative confidence value that represents the probability of obtaining a result at least as extreme as that actually obtained, assuming that the actual value was the result of chance alone."@en ;
  rdfs:subClassOf obo:OBI_0000071 .

obo:OBCS_0000320 a rdfs:Class ;
  rdfs:label "behavioural variability" ;
  rdfs:comment "‘non-rational’behaviour, discrepancies between what people say and what they actually do (cognitive dissonance), or deviations of ‘standard’ behavioural patterns (micro-level behaviour)." ;
  rdfs:subClassOf obo:OBCS_0000272 .

obo:OBI_0003143 a rdfs:Class ;
  rdfs:label "EC50 binding datum" ;
  rdfs:comment "A quantitative binding datum that is expressed as a half-maximal effective concentration (EC50)." ;
  rdfs:subClassOf obo:OBI_0001180 , obo:OBI_0003142 .

obo:OBI_0200007 a rdfs:Class ;
  rdfs:label "box-cox transformation"@en ;
  rdfs:comment "A box-cox transformation is a data transformation according to the methods of Box and Cox as described in the article Box, G. E. P. and Cox, D.R. (1964) An analysis of transformations. Journal of Royal Statistical Society, Series B, vol. 26, pp. 211-246."@en ;
  rdfs:subClassOf obo:OBI_0200169 .

obo:OBCS_0000141 a rdfs:Class ;
  rdfs:label "significance analysis of microarrays"@en ;
  rdfs:comment "An inferential statistical data analysis that is established in 2001 by Virginia Tusher, Robert Tibshirani and Gilbert Chu, for determining whether changes in gene expression are statistically significant." ;
  rdfs:subClassOf obo:OBCS_0000121 .

obo:OBI_0001225 a rdfs:Class ;
  rdfs:label "genetic population background information"@en ;
  rdfs:comment "a genetic characteristics information which is a part of genotype information that identifies the population of organisms"@en ;
  rdfs:subClassOf obo:OBI_0001404 .

obo:BFO_0000067 a rdf:Property ;
  rdfs:label "contains process"@en ;
  rdfs:comment "[copied from inverse property 'occurs in'] b occurs_in c =def b is a process and c is a material entity or immaterial entity& there exists a spatiotemporal region r and b occupies_spatiotemporal_region r.& forall(t) if b exists_at t then c exists_at t & there exist spatial regions s and s’ where & b spatially_projects_onto s at t& c is occupies_spatial_region s’ at t& s is a proper_continuant_part_of s’ at t"@en ;
  rdfs:range <https://w3id.org/linkml/Any> .

obo:BFO_0000179 a rdf:Property ;
  rdfs:label "BFO OWL specification label"@en ;
  rdfs:comment "Relates an entity in the ontology to the name of the variable that is used to represent it in the code that generates the BFO OWL file from the lispy specification."@en ;
  rdfs:range xsd:string .

obo:BFO_0000180 a rdf:Property ;
  rdfs:label "BFO CLIF specification label"@en ;
  rdfs:comment "Relates an entity in the ontology to the term that is used to represent it in the the CLIF specification of BFO2"@en ;
  rdfs:range xsd:string .

obo:IAO_0000111 a rdf:Property ;
  rdfs:label "editor preferred term"@en ;
  rdfs:comment "The concise, meaningful, and human-friendly name for a class or property preferred by the ontology developers. (US-English)"@en ;
  rdfs:range xsd:string .

obo:IAO_0000112 a rdf:Property ;
  rdfs:label "example of usage"@en ;
  rdfs:comment "A phrase describing how a term should be used and/or a citation to a work which uses it. May also include other kinds of examples that facilitate immediate understanding, such as widely know prototypes or instances of a class, or cases where a relation is said to hold."@en ;
  rdfs:range xsd:string .

obo:IAO_0000113 a rdf:Property ;
  rdfs:label "in branch"@en ;
  rdfs:comment "An annotation property indicating which module the terms belong to. This is currently experimental and not implemented yet."@en ;
  rdfs:range xsd:string .

obo:IAO_0000114 a rdf:Property ;
  rdfs:label "has curation status"@en ;
  rdfs:range xsd:string .

obo:IAO_0000115 a rdf:Property ;
  rdfs:label "definition"@en ;
  rdfs:comment "The official definition, explaining the meaning of a class or property. Shall be Aristotelian, formalized and normalized. Can be augmented with colloquial definitions."@en ;
  rdfs:range xsd:string .

obo:IAO_0000116 a rdf:Property ;
  rdfs:label "editor note"@en ;
  rdfs:comment "An administrative note intended for its editor. It may not be included in the publication version of the ontology, so it should contain nothing necessary for end users to understand the ontology."@en ;
  rdfs:range xsd:string .

obo:IAO_0000117 a rdf:Property ;
  rdfs:label "term editor"@en ;
  rdfs:comment "Name of editor entering the term in the file. The term editor is a point of contact for information regarding the term. The term editor may be, but is not always, the author of the definition, which may have been worked upon by several people"@en ;
  rdfs:range xsd:string .

obo:IAO_0000118 a rdf:Property ;
  rdfs:label "alternative label"@en ;
  rdfs:comment "A label for a class or property that can be used to refer to the class or property instead of the preferred rdfs:label. Alternative labels should be used to indicate community- or context-specific labels, abbreviations, shorthand forms and the like."@en ;
  rdfs:range xsd:string .

obo:IAO_0000119 a rdf:Property ;
  rdfs:label "definition source"@en ;
  rdfs:comment "Formal citation, e.g. identifier in external database to indicate / attribute source(s) for the definition. Free text indicate / attribute source(s) for the definition. EXAMPLE: Author Name, URI, MeSH Term C04, PUBMED ID, Wiki uri on 31.01.2007"@en ;
  rdfs:range xsd:string .

obo:IAO_0000231 a rdf:Property ;
  rdfs:label "has obsolescence reason"@en ;
  rdfs:comment "Relates an annotation property to an obsolescence reason. The values of obsolescence reasons come from a list of predefined terms, instances of the class obsolescence reason specification."@en ;
  rdfs:range xsd:string .

obo:IAO_0000232 a rdf:Property ;
  rdfs:label "curator note"@en ;
  rdfs:comment "An administrative note of use for a curator but of no use for a user"@en ;
  rdfs:range xsd:string .

obo:IAO_0000233 a rdf:Property ;
  rdfs:label "term tracker item"@en ;
  rdfs:comment "An IRI or similar locator for a request or discussion of an ontology term."@en ;
  rdfs:range xsd:string .

obo:IAO_0000234 a rdf:Property ;
  rdfs:label "ontology term requester"@en ;
  rdfs:comment "The name of the person, project, or organization that motivated inclusion of an ontology term by requesting its addition."@en ;
  rdfs:range xsd:string .

obo:IAO_0000235 a rdf:Property ;
  rdfs:label "denoted by"@en ;
  rdfs:comment "inverse of the relation 'denotes'"@en ;
  rdfs:range <https://w3id.org/linkml/Any> .

obo:IAO_0000411 a rdf:Property ;
  rdfs:label "is denotator type"@en ;
  rdfs:comment "Relates an class defined in an ontology, to the type of it's denotator"@en ;
  rdfs:range xsd:string .

obo:IAO_0000412 a rdf:Property ;
  rdfs:label "imported from"@en ;
  rdfs:comment "For external terms/classes, the ontology from which the term was imported"@en ;
  rdfs:range xsd:string .

obo:IAO_0000417 a rdf:Property ;
  rdfs:label "is quality measured as"@en ;
  rdfs:comment "inverse of the relation of is quality measurement of"@en ;
  rdfs:range <https://w3id.org/linkml/Any> .

obo:IAO_0000424 a rdf:Property ;
  rdfs:label "expand expression to"@en ;
  rdfs:comment "A macro expansion tag applied to an object property (or possibly a data property)  which can be used by a macro-expansion engine to generate more complex expressions from simpler ones"@en ;
  rdfs:range xsd:string .

obo:IAO_0000425 a rdf:Property ;
  rdfs:label "expand assertion to"@en ;
  rdfs:comment "A macro expansion tag applied to an annotation property which can be expanded into a more detailed axiom."@en ;
  rdfs:range xsd:string .

obo:IAO_0000426 a rdf:Property ;
  rdfs:label "first order logic expression"@en ;
  rdfs:range xsd:string .

obo:IAO_0000427 a rdf:Property ;
  rdfs:label "antisymmetric property"@en ;
  rdfs:comment "Use boolean value xsd:true to indicate that the property is an antisymmetric property"@en ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:OMO_0001001 .

obo:IAO_0000589 a rdf:Property ;
  rdfs:label "OBO foundry unique label"@en ;
  rdfs:comment "An alternative name for a class or property which is unique across the OBO Foundry."@en ;
  rdfs:range xsd:string .

obo:IAO_0000596 a rdf:Property ;
  rdfs:label "has ID digit count"@en ;
  rdfs:comment "Relates an ontology used to record id policy to the number of digits in the URI. The URI is: the 'has ID prefix\" annotation property value concatenated with an integer in the id range (left padded with \"0\"s to make this many digits)"@en ;
  rdfs:range xsd:string .

obo:IAO_0000597 a rdf:Property ;
  rdfs:label "has ID range allocated to"@en ;
  rdfs:comment "Relates a datatype that encodes a range of integers to the name of the person or organization who can use those ids constructed in that range to define new terms"@en ;
  rdfs:range xsd:string .

obo:IAO_0000598 a rdf:Property ;
  rdfs:label "has ID policy for"@en ;
  rdfs:comment "Relating an ontology used to record id policy to the ontology namespace whose policy it manages"@en ;
  rdfs:range xsd:string .

obo:IAO_0000599 a rdf:Property ;
  rdfs:label "has ID prefix"@en ;
  rdfs:comment "Relates an ontology used to record id policy to a prefix concatenated with an integer in the id range (left padded with \"0\"s to make this many digits) to construct an ID for a term being created."@en ;
  rdfs:range xsd:string .

obo:IAO_0000600 a rdf:Property ;
  rdfs:label "elucidation"@en ;
  rdfs:range xsd:string .

obo:IAO_0000601 a rdf:Property ;
  rdfs:label "has associated axiom(nl)"@en ;
  rdfs:range xsd:string .

obo:IAO_0000602 a rdf:Property ;
  rdfs:label "has associated axiom(fol)"@en ;
  rdfs:range xsd:string .

obo:IAO_0000603 a rdf:Property ;
  rdfs:label "is allocated id range"@en ;
  rdfs:comment "Relates an ontology IRI to an (inclusive) range of IRIs in an OBO name space. The range is give as, e.g. \"IAO_0020000-IAO_0020999\""@en ;
  rdfs:range xsd:string .

obo:IAO_0000700 a rdf:Property ;
  rdfs:label "has ontology root term"@en ;
  rdfs:comment "Ontology annotation property. Relates an ontology to a term that is a designated root term of the ontology. Display tools like OLS can use terms annotated with this property as the starting point for rendering the ontology class hierarchy. There can be more than one root."@en ;
  rdfs:range xsd:string .

obo:IAO_0006011 a rdf:Property ;
  rdfs:label "may be identical to"@en ;
  rdfs:comment "A annotation relationship between two terms in an ontology that may refer to the same (natural) type but where more evidence is required before terms are merged."@en ;
  rdfs:range xsd:string .

obo:IAO_0006012 a rdf:Property ;
  rdfs:label "scheduled for obsoletion on or after"@en ;
  rdfs:comment "Used when the class or object is scheduled for obsoletion/deprecation on or after a particular date."@en ;
  rdfs:range xsd:dateTime .

obo:IAO_0010000 a rdf:Property ;
  rdfs:label "has axiom label"@en ;
  rdfs:range xsd:string .

obo:IAO_0100001 a rdf:Property ;
  rdfs:label "term replaced by"@en ;
  rdfs:comment "Use on obsolete terms, relating the term to another term that can be used as a substitute"@en ;
  rdfs:range xsd:string .

obo:OBCS_0000221 a rdf:Property ;
  rdfs:label "mathematical formula"@en ;
  rdfs:comment "An annotation property that represents a mathematical formula." ;
  rdfs:range xsd:string .

obo:OBI_0000295 a rdf:Property ;
  rdfs:label "is_specified_input_of"@en ;
  rdfs:comment "A relation between a planned process and a continuant participating in that process that is not created during  the process. The presence of the continuant during the process is explicitly specified in the plan specification which the process realizes the concretization of."@en ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0000056 .

obo:OBI_0000833 a rdf:Property ;
  rdfs:label "objective_achieved_by" ;
  rdfs:comment "This relation obtains between an objective specification and a planned process when the criteria specified in the objective specification are met at the end of the planned process." ;
  rdfs:range <https://w3id.org/linkml/Any> .

obo:OBI_0000999 a rdf:Property ;
  rdfs:label "has category label" ;
  rdfs:comment "A relation between a categorical measurement data item and the categorical label that indicates the value of that data item on the categorical scale." ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:BFO_0000051 .

obo:OBI_0001847 a rdf:Property ;
  rdfs:label "ISA alternative term"@en ;
  rdfs:comment "An alternative term used by the ISA tools project (http://isa-tools.org)." ;
  rdfs:range xsd:string .

obo:OBI_0001886 a rdf:Property ;
  rdfs:label "NIAID GSCID-BRC alternative term"@en ;
  rdfs:comment "An alternative term used by the National Institute of Allergy and Infectious Diseases (NIAID) Genomic Sequencing Centers for Infectious Diseases (GSCID) and Bioinformatics Resource Centers (BRC)." ;
  rdfs:range xsd:string .

obo:OBI_0002135 a rdf:Property ;
  rdfs:label "has specified value"@en ;
  rdfs:comment "A relation between a value specification and a literal." ;
  rdfs:range <https://w3id.org/linkml/Any> .

obo:OBI_9991118 a rdf:Property ;
  rdfs:label "IEDB alternative term" ;
  rdfs:comment "An alternative term used by the IEDB." ;
  rdfs:range xsd:string .

obo:OMO_0001001 a rdf:Property ;
  rdfs:label "logical characteristic of object property" ;
  rdfs:comment "This is an annotation used on an object property to indicate a logical characterstic beyond what is possible in OWL." ;
  rdfs:range xsd:string .

obo:OMO_0002000 a rdf:Property ;
  rdfs:label "defined by construct" ;
  rdfs:comment "Links an annotation property to a SPARQL CONSTRUCT query which is meant to provide semantics for a shortcut relation." ;
  rdfs:range xsd:string .

obo:OMO_0003000 a rdf:Property ;
  rdfs:label "abbreviation" ;
  rdfs:comment "A synonym type for describing abbreviations or initalisms" ;
  rdfs:range xsd:string .

obo:OMO_0003001 a rdf:Property ;
  rdfs:label "ambiguous synonym" ;
  rdfs:comment "A synonym type for describing ambiguous synonyms" ;
  rdfs:range xsd:string .

obo:OMO_0003002 a rdf:Property ;
  rdfs:label "dubious synonym" ;
  rdfs:comment "A synonym type for describing dubious synonyms" ;
  rdfs:range xsd:string .

obo:OMO_0003003 a rdf:Property ;
  rdfs:label "layperson synonym" ;
  rdfs:comment "A synonym type for describing layperson or colloquial synonyms" ;
  rdfs:range xsd:string .

obo:OMO_0003004 a rdf:Property ;
  rdfs:label "plural form" ;
  rdfs:comment "A synonym type for describing pluralization synonyms" ;
  rdfs:range xsd:string .

obo:OMO_0003005 a rdf:Property ;
  rdfs:label "UK spelling synonym" ;
  rdfs:comment "A synonym type for describing UK spelling variants" ;
  rdfs:range xsd:string .

obo:OMO_0003006 a rdf:Property ;
  rdfs:label "misspelling" ;
  rdfs:comment "A synonym type for common misspellings" ;
  rdfs:range xsd:string .

obo:OMO_0003007 a rdf:Property ;
  rdfs:label "misnomer" ;
  rdfs:comment "A synonym type for misnomers, i.e., a synonym that is not technically correct but is commonly used anyway" ;
  rdfs:range xsd:string .

obo:OMO_0003008 a rdf:Property ;
  rdfs:label "previous name" ;
  rdfs:comment "A synonym type for names that have been used as primary labels in the past." ;
  rdfs:range xsd:string .

obo:OMO_0003009 a rdf:Property ;
  rdfs:label "legal name" ;
  rdfs:comment "A synonym type for the legal entity name" ;
  rdfs:range xsd:string .

obo:OMO_0003010 a rdf:Property ;
  rdfs:label "International Nonproprietary Name" ;
  rdfs:comment "The International Nonproprietary Name (INN) is a standardize name for a pharmaceutical drug or active ingredient issued by the World Health Organization (WHO) meant to address the issues with country- or language-specific brand names. These are issued in several languages, including English, Latin, French, Russian, Spanish, Arabic, and Chinese." ;
  rdfs:range xsd:string .

obo:OMO_0003011 a rdf:Property ;
  rdfs:label "latin term" ;
  rdfs:comment "A synonym type for describing Latin term synonyms." ;
  rdfs:range xsd:string .

obo:OMO_0003012 a rdf:Property ;
  rdfs:label "acronym" ;
  rdfs:comment "A synonym type for describing abbreviations that are a part of the full name's words, such as initialisms or alphabetisms." ;
  rdfs:range xsd:string .

obo:RO_0000080 a rdf:Property ;
  rdfs:label "quality of"@en ;
  rdfs:comment "a relation between a quality and an independent continuant (the bearer), in which the quality specifically depends on the bearer for its existence"@en ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0000052 .

obo:RO_0000086 a rdf:Property ;
  rdfs:label "has quality"@en ;
  rdfs:comment "a relation between an independent continuant (the bearer) and a quality, in which the quality specifically depends on the bearer for its existence"@en ;
  rdfs:range obo:BFO_0000019 ;
  rdfs:subPropertyOf obo:RO_0000053 .

obo:RO_0000092 a rdf:Property ;
  rdfs:label "disposition of"@en ;
  rdfs:comment "This relation is modeled after the BFO relation of the same name which was in BFO2, but is used in a more restricted sense - specifically, we model this relation as functional (inherited from characteristic-of). Note that this relation is now removed from BFO2020." ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0000052 .

obo:RO_0001001 a rdf:Property ;
  rdfs:label "derives into"@en ;
  rdfs:comment "a relation between two distinct material entities, the old entity and the new entity, in which the new entity begins to exist when the old entity ceases to exist, and the new entity inherits the significant portion of the matter of the old entity"@en ;
  rdfs:range <https://w3id.org/linkml/Any> .

obo:RO_0001015 a rdf:Property ;
  rdfs:label "location of"@en ;
  rdfs:comment "a relation between two independent continuants, the location and the target, in which the target is entirely within the location"@en ;
  rdfs:range <https://w3id.org/linkml/Any> .

obo:RO_0001900 a rdf:Property ;
  rdfs:label "temporal interpretation" ;
  rdfs:comment "An assertion that holds between an OWL Object Property and a temporal interpretation that elucidates how OWL Class Axioms that use this property are to be interpreted in a temporal context." ;
  rdfs:seeAlso <http://purl.obolibrary.org/obo/ro/docs/temporal-semantics/> ;
  rdfs:range xsd:string .

obo:RO_0002000 a rdf:Property ;
  rdfs:label "2D boundary of"@en ;
  rdfs:comment "a relation between a 2D immaterial entity (the boundary) and a material entity, in which the boundary delimits the material entity"@en ;
  rdfs:range <https://w3id.org/linkml/Any> .

obo:RO_0002086 a rdf:Property ;
  rdfs:label "ends after"@en ;
  rdfs:comment "X ends_after Y iff: end(Y) before_or_simultaneous_with end(X)"@en ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002222 .

obo:RO_0002091 a rdf:Property ;
  rdfs:label "starts during"@en ;
  rdfs:comment "X starts_during Y iff: (start(Y) before_or_simultaneous_with start(X)) AND (start(X) before_or_simultaneous_with end(Y))"@en ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002222 .

obo:RO_0002092 a rdf:Property ;
  rdfs:label "happens during"@en ;
  rdfs:comment "X happens_during Y iff: (start(Y) before_or_simultaneous_with start(X)) AND (end(X) before_or_simultaneous_with end(Y))"@en ;
  rdfs:seeAlso <https://wiki.geneontology.org/Happens_during> ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002093 .

obo:RO_0002093 a rdf:Property ;
  rdfs:label "ends during"@en ;
  rdfs:comment "X ends_during Y iff: ((start(Y) before_or_simultaneous_with end(X)) AND end(X) before_or_simultaneous_with end(Y). "@en ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002222 .

obo:RO_0002161 a rdf:Property ;
  rdfs:label "never in taxon" ;
  rdfs:comment "x never in taxon T if and only if T is a class, and x does not instantiate the class expression \"in taxon some T\". Note that this is a shortcut relation, and should be used as a hasValue restriction in OWL." ;
  rdfs:seeAlso <https://github.com/obophenotype/uberon/wiki/Taxon-constraints> ;
  rdfs:range xsd:string .

obo:RO_0002171 a rdf:Property ;
  rdfs:label "mutually spatially disjoint with"@en ;
  rdfs:comment "A is mutually_spatially_disjoint_with B if both A and B are classes, and there exists no p such that p is part_of some A and p is part_of some B." ;
  rdfs:seeAlso obo:RO_0002163 , <https://github.com/obophenotype/uberon/wiki/Part-disjointness-Design-Pattern> ;
  rdfs:range xsd:string .

obo:RO_0002172 a rdf:Property ;
  rdfs:label "taxonomic class assertion"@en ;
  rdfs:comment "An assertion that holds between an ontology class and an organism taxon class, which is intepreted to yield some relationship between instances of the ontology class and the taxon." ;
  rdfs:seeAlso <https://github.com/obophenotype/uberon/wiki/Taxon-constraints> ;
  rdfs:range xsd:string .

obo:RO_0002175 a rdf:Property ;
  rdfs:label "present in taxon"@en ;
  rdfs:comment "S present_in_taxon T if some instance of T has some S. This does not means that all instances of T have an S - it may only be certain life stages or sexes that have S" ;
  rdfs:seeAlso <https://github.com/obophenotype/uberon/wiki/Taxon-constraints> ;
  rdfs:range xsd:string .

obo:RO_0002222 a rdf:Property ;
  rdfs:label "temporally related to"@en ;
  rdfs:comment "A relation that holds between two occurrents. This is a grouping relation that collects together all the Allen relations." ;
  rdfs:range <https://w3id.org/linkml/Any> .

obo:RO_0002223 a rdf:Property ;
  rdfs:label "starts"@en ;
  rdfs:comment "inverse of starts with" ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:BFO_0000050 .

obo:RO_0002350 a rdf:Property ;
  rdfs:label "member of"@en ;
  rdfs:comment "is member of is a mereological relation between a item and a collection." ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:BFO_0000050 .

obo:RO_0002416 a rdf:Property ;
  rdfs:label "logical macro assertion"@en ;
  rdfs:comment "An assertion that involves at least one OWL object that is intended to be expanded into one or more logical axioms. The logical expansion can yield axioms expressed using any formal logical system, including, but not limited to OWL2-DL." ;
  rdfs:seeAlso <http://purl.obolibrary.org/obo/ro/docs/shortcut-relations/> ;
  rdfs:range xsd:string .

obo:RO_0002420 a rdf:Property ;
  rdfs:label "logical macro assertion on a class"@en ;
  rdfs:comment "A logical macro assertion whose domain is an IRI for a class" ;
  rdfs:range xsd:string .

obo:RO_0002421 a rdf:Property ;
  rdfs:label "logical macro assertion on a property"@en ;
  rdfs:comment "A logical macro assertion whose domain is an IRI for a property" ;
  rdfs:range xsd:string .

obo:RO_0002422 a rdf:Property ;
  rdfs:label "logical macro assertion on an object property"@en ;
  rdfs:comment "Used to annotate object properties to describe a logical meta-property or characteristic of the object property." ;
  rdfs:range xsd:string .

obo:RO_0004096 a rdf:Property ;
  rdfs:label "DEPRECATED inheres in"@en ;
  rdfs:comment "DEPRECATED This relation is similar to but different in important respects to the characteristic-of relation. See comments on that relation for more information." ;
  rdfs:range <https://w3id.org/linkml/Any> .

obo:RO_0004097 a rdf:Property ;
  rdfs:label "DEPRECATED bearer of"@en ;
  rdfs:range <https://w3id.org/linkml/Any> .

obo:IAO_0000409 a rdfs:Class ;
  rdfs:label "denotator type"@en ;
  rdfs:comment "A denotator type indicates how a term should be interpreted from an ontological perspective."@en ;
  rdfs:subClassOf obo:IAO_0000102 .

obo:IAO_0000410 a obo:IAO_0000409 ;
  rdfs:label "universal"@en .

obo:IAO_0000420 a obo:IAO_0000409 ;
  rdfs:label "defined class"@en ;
  rdfs:comment "A defined class is a class that is defined by a set of logically necessary and sufficient conditions but is not a universal"@en .

obo:IAO_0000421 a obo:IAO_0000409 ;
  rdfs:label "named class expression"@en ;
  rdfs:comment "A named class expression is a logical expression that is given a name. The name can be used in place of the expression."@en .

obo:OBI_0000639 a rdfs:Class ;
  rdfs:label "material separation objective" ;
  rdfs:comment "is an objective to transform a material entity into spatially separated components." ;
  rdfs:subClassOf obo:OBI_0000456 .

obo:OBI_0000678 a obo:OBI_0000639 ;
  rdfs:label "portioning objective" ;
  rdfs:comment "A material separation objective aiming to separate material into multiple portions, each of which contains a similar composition of the input material." .

obo:OBI_0000681 a obo:OBI_0000639 ;
  rdfs:label "separation into different composition objective" ;
  rdfs:comment "A material separation objective aiming to separate a material entity that has parts of different types, and end with at least one output that is a material with parts of fewer types (modulo impurities)." .

obo:OBI_0100026 a rdfs:Class ;
  rdfs:label "organism"@en ;
  rdfs:comment "A material entity that is an individual living system, such as animal, plant, bacteria or virus, that is capable of replicating or reproducing, growth and maintenance in the right environment. An organism may be unicellular or made up, like humans, of many billions of cells divided into specialized tissues and organs."@en ;
  rdfs:subClassOf obo:BFO_0000040 .

obo:NCBITaxon_10239 a obo:OBI_0100026 ;
  rdfs:label "Viruses" .

obo:NCBITaxon_2 a obo:OBI_0100026 ;
  rdfs:label "Bacteria" .

obo:NCBITaxon_2157 a obo:OBI_0100026 ;
  rdfs:label "Archaea" .

obo:NCBITaxon_2759 a obo:OBI_0100026 ;
  rdfs:label "Eukaryota" .

obo:OBI_0000963 a rdfs:Class ;
  rdfs:label "categorical label" ;
  rdfs:comment "A label that is part of a categorical datum and that indicates the value of the data item on the categorical scale." ;
  rdfs:subClassOf obo:IAO_0000009 .

obo:OBI_0000958 a obo:OBI_0000963 ;
  rdfs:label "right handed" .

obo:OBI_0000979 a obo:OBI_0000963 ;
  rdfs:label "ambidexterous" .

obo:OBI_0000998 a obo:OBI_0000963 ;
  rdfs:label "left handed" .

obo:OBCS_0000070 a rdfs:Class ;
  rdfs:label "confidence interval" ;
  rdfs:comment "A quantitative confidence value that refers to an interval give values within which there is a high probability (95 percent by convention) that the true population value can be found. The calculation of a confidence interval considers the standard deviation of the data and the number of observations. Thus, a confidence interval narrows as the number of observations increases, or its variance (dispersion) decreases." ;
  rdfs:subClassOf obo:OBI_0000071 .

obo:OBCS_0000228 a obo:OBCS_0000070 ;
  rdfs:label "95% confidence interval"@en ;
  rdfs:comment "An confidence interval with 95 percent probability that the true population value can be found." .

obo:IAO_0000225 a rdfs:Class ;
  rdfs:label "obsolescence reason specification"@en ;
  rdfs:comment "The reason for which a term has been deprecated. The allowed values come from an enumerated list of predefined terms. See the specification of these instances for more detailed definitions of each enumerated value."@en ;
  rdfs:subClassOf obo:IAO_0000102 .

obo:IAO_0000103 a obo:IAO_0000225 ;
  rdfs:label "failed exploratory term"@en ;
  rdfs:comment "The term was used in an attempt to structure part of the ontology but in retrospect failed to do a good job"@en .

obo:IAO_0000226 a obo:IAO_0000225 ;
  rdfs:label "placeholder removed"@en .

obo:IAO_0000227 a obo:IAO_0000225 ;
  rdfs:label "terms merged"@en .

obo:IAO_0000228 a obo:IAO_0000225 ;
  rdfs:label "term imported"@en .

obo:IAO_0000229 a obo:IAO_0000225 ;
  rdfs:label "term split"@en .

obo:OMO_0001000 a obo:IAO_0000225 ;
  rdfs:label "out of scope" ;
  rdfs:comment "The term was added to the ontology on the assumption it was in scope, but it turned out later that it was not."@en .

obo:IAO_0000078 a rdfs:Class ;
  rdfs:label "curation status specification"@en ;
  rdfs:comment "The curation status of the term. The allowed values come from an enumerated list of predefined terms. See the specification of these instances for more detailed definitions of each enumerated value."@en ;
  rdfs:subClassOf obo:IAO_0000102 .

obo:IAO_0000002 a obo:IAO_0000078 ;
  rdfs:label "example to be eventually removed"@en .

obo:IAO_0000120 a obo:IAO_0000078 ;
  rdfs:label "metadata complete"@en ;
  rdfs:comment "Class has all its metadata, but is either not guaranteed to be in its final location in the asserted IS_A hierarchy or refers to another class that is not complete."@en .

obo:IAO_0000121 a obo:IAO_0000078 ;
  rdfs:label "organizational term"@en ;
  rdfs:comment "Term created to ease viewing/sort terms for development purpose, and will not be included in a release"@en .

obo:IAO_0000122 a obo:IAO_0000078 ;
  rdfs:label "ready for release"@en ;
  rdfs:comment "Class has undergone final review, is ready for use, and will be included in the next release. Any class lacking \"ready_for_release\" should be considered likely to change place in hierarchy, have its definition refined, or be obsoleted in the next release.  Those classes deemed \"ready_for_release\" will also derived from a chain of ancestor classes that are also \"ready_for_release.\""@en .

obo:IAO_0000123 a obo:IAO_0000078 ;
  rdfs:label "metadata incomplete"@en ;
  rdfs:comment "Class is being worked on; however, the metadata (including definition) are not complete or sufficiently clear to the branch editors."@en .

obo:IAO_0000124 a obo:IAO_0000078 ;
  rdfs:label "uncurated"@en ;
  rdfs:comment "Nothing done yet beyond assigning a unique class ID and proposing a preferred term."@en .

obo:IAO_0000125 a obo:IAO_0000078 ;
  rdfs:label "pending final vetting"@en ;
  rdfs:comment "All definitions, placement in the asserted IS_A hierarchy and required minimal metadata are complete. The class is awaiting a final review by someone other than the term editor."@en .

obo:IAO_0000423 a obo:IAO_0000078 ;
  rdfs:label "to be replaced with external ontology term"@en ;
  rdfs:comment "Terms with this status should eventually replaced with a term from another ontology."@en .

obo:IAO_0000428 a obo:IAO_0000078 ;
  rdfs:label "requires discussion"@en ;
  rdfs:comment "A term that is metadata complete, has been reviewed, and problems have been identified that require discussion before release. Such a term requires editor note(s) to identify the outstanding issues."@en .