PREFIX obo: <http://purl.obolibrary.org/obo/>
PREFIX rdf: <http://www.w3.org/1999/02/22-rdf-syntax-ns#>
PREFIX rdfs: <http://www.w3.org/2000/01/rdf-schema#>
PREFIX xsd: <http://www.w3.org/2001/XMLSchema#>

obo:ICO_0000373 a rdfs:Class ;
  rdfs:label "designated video data"@en ;
  rdfs:comment "A 'designated data' that designates video data."@en ;
  rdfs:subClassOf obo:ICO_0000367 .

obo:OBI_0001938 a rdf:Property ;
  rdfs:label "has value specification" ;
  rdfs:comment "A relation between an information content entity and a value specification that specifies its value."@en ;
  rdfs:domain obo:IAO_0000030 ;
  rdfs:range obo:OBI_0001933 ;
  rdfs:subPropertyOf obo:BFO_0000051 .

obo:RO_0000056 a rdf:Property ;
  rdfs:label "participates in"@en ;
  rdfs:comment "a relation between a continuant and a process, in which the continuant is somehow involved in the process"@en ;
  rdfs:domain obo:BFO_0000002 ;
  rdfs:range obo:BFO_0000003 .

obo:IAO_0000235 a rdf:Property ;
  rdfs:label "denoted by"@en ;
  rdfs:comment "inverse of the relation 'denotes'"@en ;
  rdfs:domain obo:BFO_0000001 ;
  rdfs:range obo:IAO_0000030 .

obo:IAO_0000219 a rdf:Property ;
  rdfs:label "denotes"@en ;
  rdfs:comment "A primitive, instance-level, relation obtaining between an information content entity and some portion of reality. Denotation is what happens when someone creates an information content entity E in order to specifically refer to something. The only relation between E and the thing is that E can be used to 'pick out' the thing. This relation connects those two together. Freedictionary.com sense 3: To signify directly; refer to specifically"@en ;
  rdfs:domain obo:IAO_0000030 ;
  rdfs:range obo:BFO_0000001 ;
  rdfs:subPropertyOf obo:IAO_0000136 .

obo:IAO_0000136 a rdf:Property ;
  rdfs:label "is about"@en ;
  rdfs:comment "A (currently) primitive relation that relates an information artifact to an entity."@en ;
  rdfs:domain obo:IAO_0000030 ;
  rdfs:range <https://w3id.org/linkml/Any> .

obo:RO_0000058 a rdf:Property ;
  rdfs:label "is concretized as"@en ;
  rdfs:comment "A relationship between a generically dependent continuant and a specifically dependent continuant or process, in which the generically dependent continuant depends on some independent continuant or process in virtue of the fact that the specifically dependent continuant or process also depends on that same independent continuant. A generically dependent continuant may be concretized as multiple specifically dependent continuants or processes."@en ;
  rdfs:domain obo:BFO_0000031 ;
  rdfs:range xsd:string .

obo:DUO_0000046 a rdfs:Class ;
  rdfs:label "non-commercial use only"@en ;
  rdfs:comment "This data use modifier indicates that use of the data is limited to not-for-profit use."@en ;
  rdfs:subClassOf obo:DUO_0000018 .

obo:ICO_0000322 a rdfs:Class ;
  rdfs:label "consent directive"@en ;
  rdfs:comment "A 'permission directive' that prescribes some action that is made allowable by a consenting entity."@en ;
  rdfs:subClassOf obo:ICO_0000244 .

obo:ICO_0000316 a rdfs:Class ;
  rdfs:label "role directive"@en ;
  rdfs:comment "A directive information entity that prescribes some role."@en ;
  rdfs:subClassOf obo:IAO_0000033 .

<http://www.ontologyrepository.com/CommonCoreOntologies/prescribes> a rdf:Property ;
  rdfs:label "prescribes"@en ;
  rdfs:comment "For all types T1 and T2, if T1 prescribes T2, then there is some instance of T1, t1, that serves as a rule or guide to some instance of T2, t2 (if T2 is a type of bfo:Occurrent) or that serves as a model for some instance of T2, t2 (if T2 is a type of bfo:Continuant)."@en ;
  rdfs:domain obo:IAO_0000030 ;
  rdfs:range <https://w3id.org/linkml/Any> ;
  rdfs:subPropertyOf obo:IAO_0000136 .

obo:ICO_0000059 a rdfs:Class ;
  rdfs:label "ethics directive"@en ;
  rdfs:comment "A directive information entity prescribes an ethical requirement."@en ;
  rdfs:subClassOf obo:IAO_0000033 .

obo:OBI_0000655 a rdfs:Class ;
  rdfs:label "blood specimen" ;
  rdfs:comment "a material entity derived from a portion of blood collected from an organism"@en ;
  rdfs:subClassOf obo:OBI_2000009 .

obo:OBI_0000312 a rdf:Property ;
  rdfs:label "is_specified_output_of"@en ;
  rdfs:comment "A relation between a planned process and a continuant participating in that process. The presence of the continuant at the end of the process is explicitly specified in the objective specification which the process realizes the concretization of."@en ;
  rdfs:domain obo:BFO_0000002 ;
  rdfs:range obo:OBI_0000011 , obo:IAO_0000444 ;
  rdfs:subPropertyOf obo:RO_0000056 .

obo:RO_0001000 a rdf:Property ;
  rdfs:label "derives from"@en ;
  rdfs:comment "a relation between two distinct material entities, the new entity and the old entity, in which the new entity begins to exist when the old entity ceases to exist, and the new entity inherits the significant portion of the matter of the old entity"@en ;
  rdfs:range <https://w3id.org/linkml/Any> .

obo:RO_0000087 a rdf:Property ;
  rdfs:label "has role"@en ;
  rdfs:comment "a relation between an independent continuant (the bearer) and a role, in which the role specifically depends on the bearer for its existence"@en ;
  rdfs:domain obo:BFO_0000004 ;
  rdfs:range obo:BFO_0000023 ;
  rdfs:subPropertyOf obo:RO_0000053 .

obo:RO_0000085 a rdf:Property ;
  rdfs:label "has function"@en ;
  rdfs:comment "a relation between an independent continuant (the bearer) and a function, in which the function specifically depends on the bearer for its existence"@en ;
  rdfs:domain obo:BFO_0000004 ;
  rdfs:range obo:BFO_0000034 ;
  rdfs:subPropertyOf obo:RO_0000053 .

obo:RO_0000091 a rdf:Property ;
  rdfs:label "has disposition"@en ;
  rdfs:comment "a relation between an independent continuant (the bearer) and a disposition, in which the disposition specifically depends on the bearer for its existence"@en ;
  rdfs:domain obo:BFO_0000004 ;
  rdfs:range obo:BFO_0000016 ;
  rdfs:subPropertyOf obo:RO_0000053 .

obo:RO_0002002 a rdf:Property ;
  rdfs:label "has 2D boundary"@en ;
  rdfs:comment "a relation between a material entity and a 2D immaterial entity (the boundary), in which the boundary delimits the material entity"@en ;
  rdfs:domain obo:BFO_0000040 ;
  rdfs:range obo:BFO_0000141 .

obo:RO_0001025 a rdf:Property ;
  rdfs:label "located in"@en ;
  rdfs:comment "a relation between two independent continuants, the target and the location, in which the target is entirely within the location"@en ;
  rdfs:domain obo:BFO_0000004 ;
  rdfs:range <https://w3id.org/linkml/Any> .

obo:BFO_0000034 a rdfs:Class ;
  rdfs:label "function"@en ;
  rdfs:subClassOf obo:BFO_0000016 .

obo:RO_0000059 a rdf:Property ;
  rdfs:label "concretizes"@en ;
  rdfs:comment "A relationship between a specifically dependent continuant and a generically dependent continuant, in which the generically dependent continuant depends on some independent continuant in virtue of the fact that the specifically dependent continuant also depends on that same independent continuant. Multiple specifically dependent continuants can concretize the same generically dependent continuant."@en ;
  rdfs:domain obo:BFO_0000020 ;
  rdfs:range obo:BFO_0000031 .

obo:RO_0000079 a rdf:Property ;
  rdfs:label "function of"@en ;
  rdfs:comment "a relation between a function and an independent continuant (the bearer), in which the function specifically depends on the bearer for its existence"@en ;
  rdfs:domain obo:BFO_0000034 ;
  rdfs:range <https://w3id.org/linkml/Any> ;
  rdfs:subPropertyOf obo:RO_0000052 .

obo:BFO_0000054 a rdf:Property ;
  rdfs:label "realized in"@en ;
  rdfs:comment "Paraphrase of elucidation: a relation between a realizable entity and a process, where there is some material entity that is bearer of the realizable entity and participates in the process, and the realizable entity comes to be realized in the course of the process" ;
  rdfs:domain obo:BFO_0000017 ;
  rdfs:range obo:BFO_0000015 , obo:OBI_0000066 , obo:OBI_0000274 , <http://purl.obolibary.org/obo/IAO_0021001> , obo:OBI_0000471 .

obo:OBI_0002544 a rdfs:Class ;
  rdfs:label "esophagogastric junction specimen" ;
  rdfs:comment "A specimen that is derived from the esophagogastric junction."@en ;
  rdfs:subClassOf obo:OBI_0003483 .

obo:UBERON_0000465 a rdfs:Class ;
  rdfs:label "material anatomical entity" ;
  rdfs:comment "Anatomical entity that has mass." ;
  rdfs:subClassOf obo:BFO_0000040 .

obo:ICO_0000221 a rdfs:Class ;
  rdfs:label "act of informing"@en ;
  rdfs:comment "A social act in which information that is thought to be true, salient, or which is held to have a high degree of certainty is communicated to an agent that previously lacked that information."@en ;
  rdfs:subClassOf obo:IAO_0021003 .

obo:OBI_0000299 a rdf:Property ;
  rdfs:label "has_specified_output"@en ;
  rdfs:comment "The inverse property of is specified output of"@en ;
  rdfs:domain obo:OBI_0000011 ;
  rdfs:range obo:BFO_0000002 ;
  rdfs:subPropertyOf obo:RO_0000057 .

obo:BFO_0000066 a rdf:Property ;
  rdfs:label "occurs in"@en ;
  rdfs:comment "b occurs_in c =def b is a process and c is a material entity or immaterial entity& there exists a spatiotemporal region r and b occupies_spatiotemporal_region r.& forall(t) if b exists_at t then c exists_at t & there exist spatial regions s and s’ where & b spatially_projects_onto s at t& c is occupies_spatial_region s’ at t& s is a proper_continuant_part_of s’ at t"@en ;
  rdfs:domain obo:BFO_0000003 ;
  rdfs:range obo:BFO_0000004 .

obo:OBI_0000417 a rdf:Property ;
  rdfs:label "achieves_planned_objective" ;
  rdfs:comment "This relation obtains between a planned process and a objective specification when the criteria specified in the objective specification are met at the end of the planned process."@en ;
  rdfs:domain obo:OBI_0000011 ;
  rdfs:range obo:IAO_0000005 .

obo:OBI_0000293 a rdf:Property ;
  rdfs:label "has_specified_input"@en ;
  rdfs:comment "The inverse property of is specified input of"@en ;
  rdfs:domain obo:OBI_0000011 ;
  rdfs:range obo:BFO_0000002 , obo:BFO_0000040 ;
  rdfs:subPropertyOf obo:RO_0000057 .

obo:BFO_0000055 a rdf:Property ;
  rdfs:label "realizes"@en ;
  rdfs:comment "Paraphrase of elucidation: a relation between a process and a realizable entity, where there is some material entity that is bearer of the realizable entity and participates in the process, and the realizable entity comes to be realized in the course of the process" ;
  rdfs:domain obo:BFO_0000015 ;
  rdfs:range obo:BFO_0000017 .

obo:RO_0000057 a rdf:Property ;
  rdfs:label "has participant"@en ;
  rdfs:comment "a relation between a process and a continuant, in which the continuant is somehow involved in the process"@en ;
  rdfs:domain obo:BFO_0000003 ;
  rdfs:range obo:BFO_0000002 .

obo:ICO_0000344 a rdfs:Class ;
  rdfs:label "designated research purpose"@en ;
  rdfs:comment "A 'permission purpose directive' that designates a research process as its end."@en ;
  rdfs:subClassOf obo:ICO_0000328 .

obo:ICO_0000075 a rdfs:Class ;
  rdfs:label "obsolete authorization document" ;
  rdfs:comment "A document that is the output of an authorization process."@en ;
  rdfs:subClassOf <http://www.geneontology.org/formats/oboInOwl#ObsoleteClass> .

obo:IAO_0000443 a rdfs:Class ;
  rdfs:label "data item extraction from journal article" ;
  rdfs:comment "A planned process in which journal articles are read or processed and data items are extracted, typically for further analysis or indexing" ;
  rdfs:subClassOf obo:OBI_0000011 .

obo:OBI_0000102 a rdfs:Class ;
  rdfs:label "responsible party role"@en ;
  rdfs:comment "a study personnel role played by a party who is accountable for the execution of a study component and can make decisions about the conduct of the study"@en ;
  rdfs:subClassOf obo:OBI_0000202 .

obo:IAO_0021005 a rdfs:Class ;
  rdfs:label "obsolete_deontic declaration"@en ;
  rdfs:comment "A social act that brings about, transfers or revokes a socio-legal generically dependent continuant or brings about or transforms a role. Declarations do not depend on words spoken or written, but sometimes are merely actions, for instance the signing of a document."@en ;
  rdfs:subClassOf <http://www.geneontology.org/formats/oboInOwl#ObsoleteClass> .

obo:ICO_0000041 a rdfs:Class ;
  rdfs:label "informed consent rule specification"@en ;
  rdfs:comment "A directive information entity that specifies the deontic roles that are produced, revoked, or modified following a process of informed consent, where those deontic roles inhere in the human subject consenter signing an informed consent form, and the investigator or organization leading a research study or providing health care."@en ;
  rdfs:subClassOf obo:IAO_0000033 .

obo:ICO_0000276 a rdfs:Class ;
  rdfs:label "description of collected biospecimens"@en ;
  rdfs:comment "A descriptive information content entity that describes biospecimens that have been collected."@en ;
  rdfs:subClassOf <http://www.ontologyrepository.com/CommonCoreOntologies/DescriptiveInformationContentEntity> .

obo:ICO_0000120 a rdfs:Class ;
  rdfs:label "archiving signed informed consent form"@en ;
  rdfs:comment "A planned process that collect a signed  informed consent form. During this process, the information is systematically kept in a repository."@en ;
  rdfs:subClassOf obo:OBI_0000011 .

obo:OBI_0600044 a rdfs:Class ;
  rdfs:label "lavage"@en ;
  rdfs:comment "A protocol application to separate cells and/or cellular secretions from an anatomical space by the introduction and removal of fluid"@en ;
  rdfs:subClassOf obo:OBI_0600005 , obo:OBI_0600014 .

obo:NCBITaxon_117571 a rdfs:Class ;
  rdfs:label "Euteleostomi" ;
  rdfs:subClassOf obo:NCBITaxon_7742 .

obo:IAO_0000623 a rdfs:Class ;
  rdfs:label "funding source declaration section"@en ;
  rdfs:comment "A part of a document used to detail information regarding the source of funding used in support of the generation of the document content."@en ;
  rdfs:subClassOf obo:IAO_0000314 .

obo:BFO_0000051 a rdf:Property ;
  rdfs:label "has part"@en ;
  rdfs:comment "a core relation that holds between a whole and its part"@en ;
  rdfs:range <https://w3id.org/linkml/Any> , obo:IAO_0000030 .

obo:BFO_0000050 a rdf:Property ;
  rdfs:label "part of"@en ;
  rdfs:comment "a core relation that holds between a part and its whole"@en ;
  rdfs:seeAlso <http://www.obofoundry.org/ro/#OBO_REL:part_of> ;
  rdfs:range <https://w3id.org/linkml/Any> .

obo:ICO_0000414 a rdfs:Class ;
  rdfs:label "designated process of administration"@en ;
  rdfs:comment "A 'designated action' that designates a process of administration as permissable."@en ;
  rdfs:subClassOf obo:ICO_0000324 .

obo:OBI_0000094 a rdfs:Class ;
  rdfs:label "material processing"@en ;
  rdfs:comment "A planned process which results in physical changes in a specified input material"@en ;
  rdfs:subClassOf obo:OBI_0000011 .

obo:IAO_0000024 a rdfs:Class ;
  rdfs:label "obsolete_unit of measure" ;
  rdfs:comment "a unit of measure is the quality of some material entity compared to which another quality is some multiple of." ;
  rdfs:subClassOf <http://www.geneontology.org/formats/oboInOwl#ObsoleteClass> .

obo:BFO_0000017 a rdfs:Class ;
  rdfs:label "realizable entity"@en ;
  rdfs:comment "A specifically dependent continuant  that inheres in continuant  entities and are not exhibited in full at every time in which it inheres in an entity or group of entities. The exhibition or actualization of a realizable entity is a particular manifestation, functioning or process that occurs under certain circumstances."@en ;
  rdfs:subClassOf obo:BFO_0000020 .

obo:UBERON_0001988 a rdfs:Class ;
  rdfs:label "feces" ;
  rdfs:comment "Portion of semisolid bodily waste discharged through the anus[MW,modified]." ;
  rdfs:subClassOf obo:UBERON_0000463 .

obo:IAO_0000612 a rdfs:Class ;
  rdfs:label "availability textual entity"@en ;
  rdfs:comment "A textual entity expressing the location of a resource, e.g. software, or the manner in which a resource can be obtained."@en ;
  rdfs:subClassOf obo:IAO_0000300 .

obo:ICO_0000305 a rdfs:Class ;
  rdfs:label "description of future use"@en ;
  rdfs:comment "A descriptive information content entity that describes future use of material or information."@en ;
  rdfs:subClassOf <http://www.ontologyrepository.com/CommonCoreOntologies/DescriptiveInformationContentEntity> .

obo:OBI_0002126 a rdfs:Class ;
  rdfs:label "IHC-stained fixed tissue slide specimen" ;
  rdfs:comment "A fixed tissue slide specimen that is the output of immunohistochemistry slide staining."@en ;
  rdfs:subClassOf obo:OMIABIS_0000052 .

obo:ICO_0000086 a rdfs:Class ;
  rdfs:label "consenter role"@en ;
  rdfs:comment "A role that inheres in a patient or the legal guadian when he/she participates the consenting process."@en ;
  rdfs:subClassOf obo:BFO_0000023 .

obo:OBI_0000869 a rdfs:Class ;
  rdfs:label "polyA RNA extract" ;
  rdfs:comment "A RNA extract that is the output of an extraction process in which RNA molecules with poly A tail at its 3' end are purified."@en ;
  rdfs:subClassOf obo:OBI_0000880 .

obo:OBI_0000643 a rdf:Property ;
  rdfs:label "has grain" ;
  rdfs:comment "the relation of the cells in the finger of the skin to the finger, in which an indeterminate number of grains are parts of the whole by virtue of being grains in a collective that is part of the whole, and in which removing one granular part does not nec- essarily damage or diminish the whole. Ontological Whether there is a fixed, or nearly fixed number of parts - e.g. fingers of the hand, chambers of the heart, or wheels of a car - such that there can be a notion of a single one being missing, or whether, by contrast, the number of parts is indeterminate - e.g., cells in the skin of the hand, red cells in blood, or rubber molecules in the tread of the tire of the wheel of the car."@en ;
  rdfs:range <https://w3id.org/linkml/Any> , obo:CL_0000010 ;
  rdfs:subPropertyOf obo:BFO_0000051 .

obo:PATO_0001421 a rdfs:Class ;
  rdfs:label "alive" ;
  rdfs:comment "A viability quality inhering in a bearer by virtue of the bearer's condition before death." ;
  rdfs:subClassOf obo:PATO_0000169 .

obo:IAO_0000009 a rdfs:Class ;
  rdfs:label "datum label"@en ;
  rdfs:comment "A label is a symbol that is part of some other datum and is used to either partially define  the denotation of that datum or to provide a means for identifying the datum as a member of the set of data with the same label"@en ;
  rdfs:subClassOf obo:IAO_0000030 .

obo:BFO_0000145 a rdfs:Class ;
  rdfs:label "relational quality"@en ;
  rdfs:comment "b is a relational quality = Def. for some independent continuants c, d and for some time t: b quality_of c at t & b quality_of d at t. (axiom label in BFO2 Reference: [057-001])"@en ;
  rdfs:subClassOf obo:BFO_0000019 .

obo:DUO_0000029 a rdfs:Class ;
  rdfs:label "return to database or resource"@en ;
  rdfs:comment "This data use modifier indicates that the requestor must return derived/enriched data to the database/resource."@en ;
  rdfs:subClassOf obo:DUO_0000017 .

obo:IAO_8000014 a rdfs:Class ;
  rdfs:label "generated ontology module"@en ;
  rdfs:comment "An ontology module that is automatically generated, for example via a SPARQL query or via template and a CSV."@en ;
  rdfs:subClassOf obo:IAO_8000000 .

obo:OBI_0002516 a rdfs:Class ;
  rdfs:label "brain specimen" ;
  rdfs:comment "A specimen that is derived from brain."@en ;
  rdfs:subClassOf obo:OBI_0001479 .

obo:OBI_2000006 a rdfs:Class ;
  rdfs:label "upper respiratory tract specimen" ;
  rdfs:comment "A specimen that is derived from some upper respiratory tract"@en ;
  rdfs:subClassOf obo:OBI_2000005 .

obo:MONDO_0000001 a rdfs:Class ;
  rdfs:label "disease or disorder" ;
  rdfs:comment "A disease is a disposition to undergo pathological processes that exists in an organism because of one or more disorders in that organism." ;
  rdfs:subClassOf obo:BFO_0000016 .

obo:IAO_0000313 a rdfs:Class ;
  rdfs:label "patent"@en ;
  rdfs:comment "A document that has been accepted by a patent authority"@en ;
  rdfs:subClassOf obo:IAO_0000310 .

obo:DUO_0000024 a rdfs:Class ;
  rdfs:label "publication moratorium"@en ;
  rdfs:comment "This data use modifier indicates that requestor agrees not to publish results of studies until a specific date."@en ;
  rdfs:subClassOf obo:DUO_0000017 .

obo:IAO_0000319 a rdfs:Class ;
  rdfs:label "discussion section of a publication about an investigation"@en ;
  rdfs:comment "A part of a publication about an investigation that is about the study interpretation of the investigation"@en ;
  rdfs:subClassOf obo:IAO_0000314 .

obo:ICO_0000175 a rdfs:Class ;
  rdfs:label "filling questionnaire"@en ;
  rdfs:comment "A planned process that involves the filling of a questionnaire form that includes a list of questions."@en ;
  rdfs:subClassOf obo:OBI_0000011 .

obo:ICO_0000098 a rdfs:Class ;
  rdfs:label "explaining to participant candidate about the study participating information"@en ;
  rdfs:comment "A planned process that involves explanation to a human subject candidate with relevant study information, including study purpose, protocol, and human subject benefits and risks, that indicated in an informed consent form."@en ;
  rdfs:subClassOf obo:OBI_0000011 .

obo:ICO_0000254 a rdfs:Class ;
  rdfs:label "witness role"@en ;
  rdfs:comment "A role inhering in an agent as a result of that agent having observed some process."@en ;
  rdfs:subClassOf obo:BFO_0000023 .

obo:OBI_0002549 a rdfs:Class ;
  rdfs:label "ovary specimen" ;
  rdfs:comment "A specimen that is derived from female gonad."@en ;
  rdfs:subClassOf obo:OBI_0001479 .

obo:ICO_0000172 a rdfs:Class ;
  rdfs:label "yes answer text entity"@en ;
  rdfs:comment "A filled multiple choice text entity that records a response indicating 'yes' to a multiple choice question."@en ;
  rdfs:subClassOf obo:ICO_0000171 .

obo:OBI_0002538 a rdfs:Class ;
  rdfs:label "cerebellum specimen" ;
  rdfs:comment "A specimen that is derived from cerebellum."@en ;
  rdfs:subClassOf obo:OBI_0002516 .

obo:ICO_0000403 a rdfs:Class ;
  rdfs:label "designated unspecified actor"@en ;
  rdfs:comment "A 'designated actor' that designates an unspecified actor."@en ;
  rdfs:subClassOf obo:ICO_0000325 .

obo:IAO_0000055 a rdfs:Class ;
  rdfs:label "rule"@en ;
  rdfs:comment "A rule is an executable which guides, defines, restricts actions."@en ;
  rdfs:subClassOf obo:IAO_0000001 .

obo:ICO_0000426 a rdfs:Class ;
  rdfs:label "limited data set"@en ;
  rdfs:comment "Protected health information that excludes HIPAA-specified identifiers of the individual or of relatives, employers, or household members of the individual."@en ;
  rdfs:subClassOf obo:ICO_0000103 .

obo:OBI_0000880 a rdfs:Class ;
  rdfs:label "RNA extract" ;
  rdfs:comment "an extract which is the output of an extraction process in which RNA molecules are isolated from a specimen."@en ;
  rdfs:subClassOf obo:OBI_0001010 .

obo:ICO_0000217 a rdfs:Class ;
  rdfs:label "act of anonymizing"@en ;
  rdfs:comment "A planned process that involves altering an information content entity that is associated with an individual, such that such association is lost or inaccessible."@en ;
  rdfs:subClassOf obo:OBI_0000011 .

obo:OBI_0000832 a rdfs:Class ;
  rdfs:label "measurement device" ;
  rdfs:comment "A device in which a measure function inheres."@en ;
  rdfs:subClassOf obo:OBI_0000968 .

obo:IAO_0000416 a rdfs:Class ;
  rdfs:label "time measurement datum"@en ;
  rdfs:comment "A scalar measurement datum that is the result of measuring a temporal interval"@en ;
  rdfs:subClassOf obo:IAO_0000032 .

obo:IAO_0000004 a rdf:Property ;
  rdfs:label "has measurement value"@en ;
  rdfs:domain obo:IAO_0000032 ;
  rdfs:range xsd:double .

obo:IAO_0000413 a rdf:Property ;
  rdfs:label "is duration of"@en ;
  rdfs:comment "relates a process to a time-measurement-datum that represents the duration of the process"@en ;
  rdfs:domain obo:IAO_0000416 ;
  rdfs:range obo:BFO_0000015 ;
  rdfs:subPropertyOf obo:IAO_0000136 .

obo:IAO_0000221 a rdf:Property ;
  rdfs:label "is quality measurement of"@en ;
  rdfs:comment "m is a quality measurement of q at t. When q is a quality, there is a measurement process p that has specified output m, a measurement datum, that is about q"@en ;
  rdfs:domain obo:IAO_0000109 ;
  rdfs:range obo:BFO_0000019 , obo:PATO_0000125 ;
  rdfs:subPropertyOf obo:IAO_0000136 .

obo:IAO_0000039 a rdf:Property ;
  rdfs:label "has measurement unit label"@en ;
  rdfs:range obo:UO_0000003 , obo:UO_0000002 , obo:IAO_0000003 ;
  rdfs:subPropertyOf obo:BFO_0000051 .

obo:OBI_0002607 a rdfs:Class ;
  rdfs:label "oral swab specimen" ;
  rdfs:comment "A specimen that is collected with a swab from the inside surface of a mouth."@en ;
  rdfs:subClassOf obo:OBI_0001479 , obo:OBI_0002599 .

obo:OBI_0001933 a rdfs:Class ;
  rdfs:label "value specification" ;
  rdfs:comment "An information content entity that specifies a value within a classification scheme or on a quantitative scale."@en ;
  rdfs:subClassOf obo:IAO_0000030 .

obo:IAO_8000003 a rdfs:Class ;
  rdfs:label "main release ontology module"@en ;
  rdfs:comment "An ontology module that is intended to be the primary release product and the one consumed by the majority of tools."@en ;
  rdfs:subClassOf obo:IAO_8000000 .

obo:ICO_0000164 a rdfs:Class ;
  rdfs:label "subject withdrawal with sample stored for unlimited time"@en ;
  rdfs:comment "A planned process that represents a study participant withdrawing from the study and agreeing to have the participant sample stored for unlimited time."@en ;
  rdfs:subClassOf obo:OBI_0000011 .

obo:ICO_0000077 a rdfs:Class ;
  rdfs:label "obsolete benefit" ;
  rdfs:comment "A benefit is a disposition or the potential positive effects that may arise from participating in a study."@en ;
  rdfs:subClassOf <http://www.geneontology.org/formats/oboInOwl#ObsoleteClass> .

obo:ICO_0000232 a rdfs:Class ;
  rdfs:label "obsolete regulatory body" ;
  rdfs:comment "An organization that has a deontic power role prescribed by some regulatory document that occurs in a stasis of regulation."@en ;
  rdfs:subClassOf <http://www.geneontology.org/formats/oboInOwl#ObsoleteClass> .

obo:IAO_0000645 a rdfs:Class ;
  rdfs:label "tables section"@en ;
  rdfs:comment "A part of a document that contains one or more tables."@en ;
  rdfs:subClassOf obo:IAO_0000314 .

obo:UBERON_0000948 a rdfs:Class ;
  rdfs:label "heart" ;
  rdfs:comment "A myogenic muscular circulatory organ found in the vertebrate cardiovascular system composed of chambers of cardiac muscle. It is the primary circulatory organ." ;
  rdfs:subClassOf obo:UBERON_0000465 .

obo:ICO_0000355 a rdfs:Class ;
  rdfs:label "designated unspecified purpose"@en ;
  rdfs:comment "A 'permission purpose directive' that designates an unspecified process as its end."@en ;
  rdfs:subClassOf obo:ICO_0000328 .

obo:ICO_0000243 a rdfs:Class ;
  rdfs:label "consequent directive"@en ;
  rdfs:comment "A directive information entity that enumerates the results if a trigger condition describing failure to comply with a rule is met."@en ;
  rdfs:subClassOf obo:IAO_0000033 .

obo:IAO_0000013 a rdfs:Class ;
  rdfs:label "journal article"@en ;
  rdfs:comment "A report that is published in a journal."@en ;
  rdfs:subClassOf obo:IAO_0000088 , obo:IAO_0000311 .

obo:OBI_0002555 a rdfs:Class ;
  rdfs:label "age group inclusion criterion"@en ;
  rdfs:comment "An inclusion criterion that defines and states an age bracket which, if met, makes an entity suitable for a given task or participation in a given process."@en ;
  rdfs:subClassOf obo:OBI_0500027 .

obo:IAO_0000302 a rdfs:Class ;
  rdfs:label "author identification"@en ;
  rdfs:comment "A textual entity intended to identify a particular author"@en ;
  rdfs:subClassOf obo:IAO_0000590 .

obo:ICO_0000311 a rdfs:Class ;
  rdfs:label "act of genetic testing"@en ;
  rdfs:comment "A planned process that involves the investigation of some sequence of DNA."@en ;
  rdfs:subClassOf obo:OBI_0000011 .

obo:OBI_0002425 a rdfs:Class ;
  rdfs:label "radiation treatment exclusion criteria" ;
  rdfs:comment "An exclusion criterion that defines whether radiation was received or is being received for a previous  or current cancer, which when met, makes an individual unsuitable for a given task or participation in a given process"@en ;
  rdfs:subClassOf obo:OBI_0500028 .

obo:PATO_0000169 a rdfs:Class ;
  rdfs:label "viability" ;
  rdfs:comment "An organismal quality inhering in a bearer or a population by virtue of the bearer's disposition to survive and develop normally or the number of surviving individuals in a given population." ;
  rdfs:subClassOf obo:PATO_0001995 .

obo:UBERON_0001037 a rdfs:Class ;
  rdfs:label "strand of hair" ;
  rdfs:comment "A filament, mostly protein, that grows from follicles found in the dermis[WP]." ;
  rdfs:subClassOf obo:UBERON_0000465 .

obo:BFO_0000030 a rdfs:Class ;
  rdfs:label "object"@en ;
  rdfs:subClassOf obo:BFO_0000040 .

obo:UBERON_0001155 a rdfs:Class ;
  rdfs:label "colon" ;
  rdfs:comment "A portion of the large intestine before it becomes the rectum. In mammals, the colon is the most part of the large intestine, excluding the vermiform appendix, the rectum and the anal canal." ;
  rdfs:subClassOf obo:UBERON_0000465 .

obo:NCBITaxon_314146 a rdfs:Class ;
  rdfs:label "Euarchontoglires" ;
  rdfs:subClassOf obo:NCBITaxon_40674 .

<http://purl.obolibary.org/obo/IAO_0021001> a rdfs:Class ;
  rdfs:label "obsolete_deontic document act"@en ;
  rdfs:comment "A deontic declaration creating or revoking a deontic role by lawfully manipulating (signing, stamping, publishing) a document."@en ;
  rdfs:subClassOf <http://www.geneontology.org/formats/oboInOwl#ObsoleteClass> .

obo:IAO_0000606 a rdfs:Class ;
  rdfs:label "abbreviations section"@en ;
  rdfs:comment "A part of a document where abbreviations and their long-forms used within the document are listed."@en ;
  rdfs:subClassOf obo:IAO_0000314 .

obo:ICO_0000189 a rdfs:Class ;
  rdfs:label "contact directive"@en ;
  rdfs:comment "A directive information entity that prescribes a human being who is to bear a contact role."@en ;
  rdfs:subClassOf obo:IAO_0000033 .

obo:OBI_0002530 a rdfs:Class ;
  rdfs:label "adipose tissue specimen" ;
  rdfs:comment "A specimen that is derived from adipose tissue."@en ;
  rdfs:subClassOf obo:OBI_0001479 .

obo:ICO_0000026 a rdfs:Class ;
  rdfs:label "obsolete expiration date specification in informed consent form" ;
  rdfs:comment "A date specification in an informed consent form that specifies the expiration date of an investigation."@en ;
  rdfs:subClassOf <http://www.geneontology.org/formats/oboInOwl#ObsoleteClass> .

obo:ICO_0000377 a rdfs:Class ;
  rdfs:label "designated unspecified object"@en ;
  rdfs:comment "A 'designated object' that designates an unspecified object."@en ;
  rdfs:subClassOf obo:ICO_0000326 .

obo:ICO_0000153 a rdfs:Class ;
  rdfs:label "obsolete consenting to be contacted for tissue research" ;
  rdfs:subClassOf <http://www.geneontology.org/formats/oboInOwl#ObsoleteClass> .

obo:PATO_0001985 a rdfs:Class ;
  rdfs:label "frozen" ;
  rdfs:comment "A quality inhering in a bearer by virtue of the bearer's being kept below its freezing point." ;
  rdfs:subClassOf obo:PATO_0000146 .

obo:IAO_0000183 a rdfs:Class ;
  rdfs:label "dendrogram"@en ;
  rdfs:comment """A dendrogram is a report graph which is a tree diagram
frequently used to illustrate the arrangement of the clusters produced by a
clustering algorithm."""@en ;
  rdfs:subClassOf obo:IAO_0000038 .

obo:OBI_0500000 a rdfs:Class ;
  rdfs:label "study design"@en ;
  rdfs:comment "A plan specification comprised of protocols (which may specify how and what kinds of data will be gathered) that are executed as part of an investigation and is realized during a study design execution." ;
  rdfs:subClassOf obo:IAO_0000104 .

obo:ICO_0000104 a rdfs:Class ;
  rdfs:label "informed consent form containing questionnaire"@en ;
  rdfs:comment "An informed consent form that contains a questionnaire section."@en .

obo:ICO_0000170 a rdfs:Class ;
  rdfs:label "filled questionnaire"@en ;
  rdfs:comment "A questionnaire that is filled up with answers."@en ;
  rdfs:subClassOf obo:OBI_0001000 .

obo:ICO_0000340 a rdfs:Class ;
  rdfs:label "designated process of sharing"@en ;
  rdfs:comment "A 'designated action' that designates a process of sharing permissable."@en ;
  rdfs:subClassOf obo:ICO_0000324 .

obo:UBERON_3000016 a rdfs:Class ;
  rdfs:label "anterior nasal wall" ;
  rdfs:comment "Paired, vertical, and relatively straight plates that form the anterior limit of the nasal capsule." ;
  rdfs:subClassOf obo:UBERON_0000465 .

obo:OMRSE_00000024 a rdfs:Class ;
  rdfs:label "obsolete role in human social processes"@en ;
  rdfs:comment "A role inhering in an entity realized by social interactions in human society."@en ;
  rdfs:subClassOf obo:BFO_0000023 .

obo:IAO_0000323 a rdfs:Class ;
  rdfs:label "author contributions section"@en ;
  rdfs:comment "A part of a publication that is about the specific contributions of each author"@en ;
  rdfs:subClassOf obo:IAO_0000314 .

obo:IAO_0000422 a rdfs:Class ;
  rdfs:label "postal address"@en ;
  rdfs:comment "A textual entity that is used as directive to deliver something to a person, or organization" ;
  rdfs:subClassOf obo:IAO_0000300 .

obo:CL_0000842 a rdfs:Class ;
  rdfs:label "mononuclear cell" ;
  rdfs:comment "A leukocyte with a single non-segmented nucleus in the mature form." ;
  rdfs:subClassOf obo:CL_0000000 .

obo:OBI_0002573 a rdfs:Class ;
  rdfs:label "polyA depleted RNA extract" ;
  rdfs:comment "A RNA extract that is the output of an extraction process in which RNA molecules lacking poly A tails at thier 3' ends are purified."@en ;
  rdfs:subClassOf obo:OBI_0000880 .

obo:IAO_0000580 a rdfs:Class ;
  rdfs:label "looking up a centrally registered identifier"@en ;
  rdfs:comment "A planned process in which a request to a CRID registry is made to return the information associated with a CRID symbol"@en ;
  rdfs:subClassOf obo:OBI_0000011 .

obo:ICO_0000380 a rdfs:Class ;
  rdfs:label "designated corporation"@en ;
  rdfs:comment "A 'designated actor' that designates a corporation."@en ;
  rdfs:subClassOf obo:ICO_0000325 .

obo:ICO_0000069 a rdfs:Class ;
  rdfs:label "contact person for questions about research"@en ;
  rdfs:comment "A person who is the contact for questions about research."@en ;
  rdfs:subClassOf obo:NCBITaxon_9606 .

obo:OBI_0002426 a rdfs:Class ;
  rdfs:label "chemotherapy treatment within the recent past exclusion criterion" ;
  rdfs:comment "An exclusion criterion that defines whether chemotherapy was received within a certain timeframe, which when met, makes an individual unsuitable for a given task or participation in a given process."@en ;
  rdfs:subClassOf obo:OBI_0500028 .

obo:IAO_0021001 a rdfs:Class ;
  rdfs:label "deontic document act"@en ;
  rdfs:comment "A deontic declaration creating or revoking a deontic role by lawfully manipulating (signing, stamping, publishing) a document."@en ;
  rdfs:subClassOf obo:IAO_0021009 .

obo:IAO_0021011 a rdf:Property ;
  rdfs:label "legally revokes"@en ;
  rdfs:comment """d socio-legally revokes s if s participates in d and at the end of d s no longer exists.
It is important to note that this going out of existence of s is complete and unlike the going out of existence for material entities which basically always are transformed into something else. After the declaration nothing is left of the socio-legal generically dependent continuant in question."""@en ;
  rdfs:domain obo:IAO_0021009 ;
  rdfs:range obo:IAO_0021008 ;
  rdfs:subPropertyOf obo:RO_0000057 .

obo:OBI_0002454 a rdfs:Class ;
  rdfs:label "clinically relevant lifestyle inclusion criterion"@en ;
  rdfs:comment "An inclusion criterion that defines and states one or more clinically relevant planned processes that a human being actively participates in , which, if met, makes the human being suitable for a given task or participation in a given process."@en ;
  rdfs:subClassOf obo:OBI_0500027 .

obo:ICO_0000268 a rdfs:Class ;
  rdfs:label "confidentiality directive"@en ;
  rdfs:comment "A directive information entity that prescribes the nondisclosure of information."@en ;
  rdfs:subClassOf obo:IAO_0000033 .

obo:UBERON_0000173 a rdfs:Class ;
  rdfs:label "amniotic fluid" ;
  rdfs:comment "Amniotic fluid is a bodily fluid consisting of watery liquid surrounding and cushioning a growing fetus within the amnion. It allows the fetus to move freely without the walls of the uterus being too tight against its body. Buoyancy is also provided. The composition of the fluid changes over the course of gestation. Initially, amniotic fluid is similar to maternal plasma, mainly water with electrolytes. As the fetus develops, proteins, carbohydrates, lipids, phospholipids originating from the lungs, fetal cells, and urea are deposited in the fluid." ;
  rdfs:subClassOf obo:UBERON_0000463 .

obo:OBI_0302887 a rdfs:Class ;
  rdfs:label "staining"@en ;
  rdfs:comment "Staining is a process which results in the addition a class-specific (DNA, proteins, lipids, carbohydrates) dye to a substrate to qualify or quantify the presence of a specific compound."@en ;
  rdfs:subClassOf obo:OBI_0000094 .

obo:ICO_0000279 a rdfs:Class ;
  rdfs:label "description of procedure for obtaining further information"@en ;
  rdfs:comment "A descriptive information content entity that describes some procedure for obtaining information only available at some future time."@en ;
  rdfs:subClassOf <http://www.ontologyrepository.com/CommonCoreOntologies/DescriptiveInformationContentEntity> .

obo:CL_0000558 a rdfs:Class ;
  rdfs:label "reticulocyte" ;
  rdfs:comment "An immature erythrocyte that changes the protein composition of its plasma membrane by exosome formation and extrusion. The types of protein removed differ between species though removal of the transferrin receptor is apparent in mammals and birds." ;
  rdfs:subClassOf obo:CL_0000000 .

obo:UBERON_0000162 a rdfs:Class ;
  rdfs:label "cloaca" ;
  rdfs:comment "Common chamber into which the intestines and excretory system opens. Arises during development in all vertebrates, but in many it becomes subdivided, lost or incorporated into other structures." ;
  rdfs:subClassOf obo:UBERON_0000465 .

obo:ICO_0000030 a rdfs:Class ;
  rdfs:label "informed consent form for storage and future use of unused samples"@en ;
  rdfs:comment "An informed consent form that is used for a storage and future use of unused samples."@en .

obo:BFO_0000006 a rdfs:Class ;
  rdfs:label "spatial region"@en ;
  rdfs:subClassOf obo:BFO_0000141 .

obo:OBI_1000049 a rdfs:Class ;
  rdfs:label "whole mount tissue" ;
  rdfs:comment "A whole organism preparation resulting from a histological preparation known as whole mount preparation where the whole specimen is mounted or spread on the microscope (glass) slide"@en ;
  rdfs:subClassOf obo:OBI_0000680 , obo:OBI_0000953 .

obo:IAO_0000628 a rdfs:Class ;
  rdfs:label "genome announcement textual entity"@en ;
  rdfs:comment "A textual entity that describes the generation and public release of a novel, draft genome sequence."@en ;
  rdfs:subClassOf obo:IAO_0000300 .

obo:UBERON_0000178 a rdfs:Class ;
  rdfs:label "blood" ;
  rdfs:comment "A fluid that is composed of blood plasma and erythrocytes." ;
  rdfs:subClassOf obo:UBERON_0006314 .

obo:IAO_8000000 a rdfs:Class ;
  rdfs:label "ontology module"@en ;
  rdfs:subClassOf obo:IAO_0000102 .

obo:BFO_0000182 a rdfs:Class ;
  rdfs:label "history"@en ;
  rdfs:subClassOf obo:BFO_0000015 .

obo:OBI_0000047 a rdfs:Class ;
  rdfs:label "processed material"@en ;
  rdfs:comment "Is a material entity that is created or changed during material processing."@en ;
  rdfs:subClassOf obo:BFO_0000040 .

obo:ICO_0000088 a rdfs:Class ;
  rdfs:label "participation duration"@en ;
  rdfs:comment "A temporal interval during which a human being participates in a process."@en ;
  rdfs:subClassOf obo:BFO_0000038 .

obo:ICO_0000250 a rdfs:Class ;
  rdfs:label "liability directive"@en ;
  rdfs:comment "A directive information entity that prescribes the agent that is liable if a trigger condition is met."@en ;
  rdfs:subClassOf obo:IAO_0000033 .

obo:DUO_0000012 a rdfs:Class ;
  rdfs:label "research specific restrictions"@en ;
  rdfs:comment "This data use modifier indicates that use is limited to studies of a certain research type."@en ;
  rdfs:subClassOf obo:DUO_0000017 .

obo:DUO_0000010 a rdf:Property ;
  rdfs:label "is restricted to" ;
  rdfs:comment "A is restricted to B iff A is a consent code and B is an investigation and A may only participate in instances of a class C, of which B is an instance." ;
  rdfs:range <https://w3id.org/linkml/Any> .

obo:IAO_8000018 a rdfs:Class ;
  rdfs:label "obo basic subset ontology module"@en ;
  rdfs:comment """A subset ontology that is designed for basic applications to continue to make certain simplifying assumptions; many of these simplifying assumptions were based on the initial version of the Gene Ontology, and have become enshrined in many popular and useful tools such as term enrichment tools.

Examples of such assumptions include: traversing the ontology graph ignoring relationship types using a naive algorithm will not lead to cycles (i.e. the ontology is a DAG); every referenced term is declared in the ontology (i.e. there are no dangling clauses).

An ontology is OBO Basic if and only if it has the following characteristics:
DAG
Unidirectional
No Dangling Clauses
Fully Asserted
Fully Labeled
No equivalence axioms
Singly labeled edges
No qualifier lists
No disjointness axioms
No owl-axioms header
No imports"""@en ;
  rdfs:seeAlso <http://owlcollab.github.io/oboformat/doc/obo-syntax.html#6.2> ;
  rdfs:subClassOf obo:IAO_8000017 .

obo:ICO_0000287 a rdfs:Class ;
  rdfs:label "minor role"@en ;
  rdfs:comment "A role inhering in a Homo sapiens that, if realized, is realized within the organizational context of a legal jurisdiction, when the bearer fails to meet the legal threshold for adulthood."@en ;
  rdfs:subClassOf obo:BFO_0000023 .

obo:ICO_0000327 a rdfs:Class ;
  rdfs:label "permission condition directive"@en ;
  rdfs:comment "A 'directive information entity' that directs the conditions of 'allowability' for a 'consent directive'."@en ;
  rdfs:subClassOf obo:IAO_0000033 .

obo:ICO_0000064 a rdfs:Class ;
  rdfs:label "study requiring informed consent"@en ;
  rdfs:comment "An investigation that requires an informed consent process."@en ;
  rdfs:subClassOf obo:OBI_0000066 .

obo:ICO_0000208 a rdf:Property ;
  rdfs:label "has permission"@en ;
  rdfs:comment "An object property that represents a relation between a research project and its associated permission type under the categery of 'information content entity'." ;
  rdfs:domain obo:OBI_0000066 ;
  rdfs:range obo:IAO_0000030 .

obo:OBI_0002505 a rdfs:Class ;
  rdfs:label "milk specimen" ;
  rdfs:comment "A specimen that is derived from milk."@en ;
  rdfs:subClassOf obo:OBI_2000009 .

obo:UBERON_0002046 a rdfs:Class ;
  rdfs:label "thyroid gland" ;
  rdfs:comment "A two-lobed endocrine gland found in all vertebrates, located in front of and on either side of the trachea in humans, and producing various hormones, such as triiodothyronine and calcitonin[BTO]." ;
  rdfs:subClassOf obo:UBERON_0000465 .

obo:OBI_0000981 a rdfs:Class ;
  rdfs:label "agar stab specimen" ;
  rdfs:comment "a specimen that is output of a process that cell culture inoculated into agar for long term storage."@en ;
  rdfs:subClassOf obo:OBI_0001472 , obo:OBI_0100051 .

obo:ICO_0000366 a rdfs:Class ;
  rdfs:label "possibility of withdraw directive"@en ;
  rdfs:comment "A 'permission requirement directive' that directs the possibility of withdraw."@en ;
  rdfs:subClassOf obo:ICO_0000364 .

obo:OBI_0002533 a rdfs:Class ;
  rdfs:label "colon specimen" ;
  rdfs:comment "A specimen that is derived from colon."@en ;
  rdfs:subClassOf obo:OBI_0003483 .

obo:UBERON_0001729 a rdfs:Class ;
  rdfs:label "oropharynx" ;
  rdfs:comment "The portion of the pharynx that lies between the soft palate and the upper edge of the epiglottis." ;
  rdfs:subClassOf obo:UBERON_0000465 .

obo:OBI_0666667 a rdfs:Class ;
  rdfs:label "nucleic acid extraction"@en ;
  rdfs:comment "a material separation to recover the nucleic acid fraction of an input material"@en ;
  rdfs:subClassOf obo:OBI_0302884 .

obo:IAO_0000035 a rdfs:Class ;
  rdfs:label "obsolete_study interpretation"@en ;
  rdfs:comment "A study interpretation is a textual entity about the implications of a study result. Examples include discussion of whether a hypothesis is false, whether the study failed to address the hypothesis, and whether the study results have led to new hypotheses"@en ;
  rdfs:subClassOf <http://www.geneontology.org/formats/oboInOwl#ObsoleteClass> .

obo:ICO_0000391 a rdfs:Class ;
  rdfs:label "designated regulatory organization"@en ;
  rdfs:comment "A 'designated organization' that designates a regulatory organization."@en ;
  rdfs:subClassOf obo:ICO_0000384 .

obo:ICO_0000351 a rdfs:Class ;
  rdfs:label "designated commercial purpose"@en ;
  rdfs:comment "A 'permission purpose directive' that designates a for-profit activity as its end."@en ;
  rdfs:subClassOf obo:ICO_0000328 .

obo:UBERON_0001359 a rdfs:Class ;
  rdfs:label "cerebrospinal fluid" ;
  rdfs:comment "A clear, colorless, bodily fluid, that occupies the subarachnoid space and the ventricular system around and inside the brain and spinal cord." ;
  rdfs:subClassOf obo:UBERON_0006314 .

obo:ICO_0000300 a rdfs:Class ;
  rdfs:label "act of regulatory supervision"@en ;
  rdfs:comment "A planned process in which a regulatory body directs or monitors another planned process."@en ;
  rdfs:subClassOf obo:OBI_0000011 .

obo:ICO_0000298 a rdfs:Class ;
  rdfs:label "stasis of law"@en ;
  rdfs:comment "A stasis of regulation that has participant some information content entity and during which that information content entity is recognized as a law within the jurisdiction in which the stasis of regulation is occurring."@en ;
  rdfs:subClassOf obo:ICO_0000297 .

obo:IAO_0000403 a rdfs:Class ;
  rdfs:label "three dimensional cartesian spatial coordinate datum"@en ;
  rdfs:comment "A cartesion spatial coordinate datum that  uses three values to specify a position within a three dimensional spatial region"@en ;
  rdfs:subClassOf obo:IAO_0000400 .

obo:IAO_0000405 a rdf:Property ;
  rdfs:label "has z coordinate value"@en ;
  rdfs:domain obo:IAO_0000400 ;
  rdfs:range xsd:float .

obo:IAO_0000404 a rdf:Property ;
  rdfs:label "has x coordinate value"@en ;
  rdfs:domain obo:IAO_0000400 ;
  rdfs:range xsd:float .

obo:IAO_0000406 a rdf:Property ;
  rdfs:label "has y coordinate value"@en ;
  rdfs:domain obo:IAO_0000400 ;
  rdfs:range xsd:float .

obo:IAO_0000407 a rdf:Property ;
  rdfs:label "has coordinate unit label"@en ;
  rdfs:comment "relating a cartesian spatial coordinate datum to a unit label that together with the values represent a point"@en ;
  rdfs:domain obo:IAO_0000400 ;
  rdfs:range obo:UO_0000001 ;
  rdfs:subPropertyOf obo:BFO_0000051 .

obo:PATO_0001018 a rdfs:Class ;
  rdfs:label "physical quality" ;
  rdfs:comment "A quality of a physical entity that exists through action of continuants at the physical level of organisation in relation to other entities." ;
  rdfs:subClassOf obo:PATO_0001241 .

obo:OBI_0400106 a rdfs:Class ;
  rdfs:label "centrifuge" ;
  rdfs:comment "A device with a rapidly rotating container that applies centrifugal force to its contents"@en ;
  rdfs:subClassOf obo:OBI_0000832 , obo:OBI_0000932 .

obo:ICO_0000131 a rdfs:Class ;
  rdfs:label "institutional review board approval number"@en ;
  rdfs:comment "A review board approval number that is assigned by an institutional review board."@en ;
  rdfs:subClassOf obo:ICO_0000111 .

obo:IAO_0000617 a rdfs:Class ;
  rdfs:label "conflict of interest textual entity"@en ;
  rdfs:comment "A textual entity that expresses a situation involving one or more of the authors, or the funding source of a document whereby the authors or funding source stand to potentially gain (typically financially) from the results reported in the document."@en ;
  rdfs:subClassOf obo:IAO_0000300 .

obo:ICO_0000423 a rdfs:Class ;
  rdfs:label "act of selling"@en ;
  rdfs:comment "A planned process in which goods or services are exachanged for money."@en ;
  rdfs:subClassOf obo:OBI_0000011 .

obo:ICO_0000335 a rdfs:Class ;
  rdfs:label "designated process of duplication"@en ;
  rdfs:comment "A 'designated action' that designates a process of duplication as permissable."@en ;
  rdfs:subClassOf obo:ICO_0000324 .

obo:IAO_0000132 a rdfs:Class ;
  rdfs:label "lot number"@en ;
  rdfs:comment "A lot number is an information content entity which is an identical sequence of character borne by part of manufactured product or its packaging for each instances of a product class in a discrete batch of an item. Lot numbers are usually assigned to each separate production run of an item. Manufacturing as a lot might be due to a variety of reasons, for example,  a single process during which many individuals are made from the same portion of source material. Lot numbers can be encoded in a pattern  of other information objects, such as bar codes, numerals, or patterns of dots."@en ;
  rdfs:subClassOf obo:IAO_0000028 .

obo:OBI_0002562 a rdfs:Class ;
  rdfs:label "country of residence inclusion criteria"@en ;
  rdfs:comment "An inclusion criterion that defines and states one or more countries of residence which, if met, makes a human being suitable for a given task or participation in a given process."@en ;
  rdfs:subClassOf obo:OBI_0500027 .

obo:OBI_0002613 a rdfs:Class ;
  rdfs:label "environmental swab specimen" ;
  rdfs:comment "A specimen that is collected with a swab from the surface of an environmenal material."@en ;
  rdfs:subClassOf obo:OBI_0002599 , obo:OBI_0100051 .

obo:DUO_0000034 a rdfs:Class ;
  rdfs:label "age category research" ;
  rdfs:comment "An investigation concerning specific age categories." ;
  rdfs:subClassOf obo:OBI_0000066 .

obo:IAO_0000001 a rdfs:Class ;
  rdfs:label "conditional specification"@en ;
  rdfs:comment "A directive information entity that specifies what should happen if the trigger condition is fulfilled."@en ;
  rdfs:subClassOf obo:IAO_0000033 .

obo:IAO_0000593 a rdfs:Class ;
  rdfs:label "software library"@en ;
  rdfs:comment "A software library is software composed of a collection of software modules and/or software methods in a form that can be statically or dynamically linked to some software application."@en ;
  rdfs:subClassOf obo:IAO_0000010 .

obo:OBI_2000013 a rdfs:Class ;
  rdfs:label "arterial blood specimen" ;
  rdfs:comment "A specimen that is derived from some arterial blood"@en ;
  rdfs:subClassOf obo:OBI_0000655 .

obo:ICO_0000261 a rdfs:Class ;
  rdfs:label "obsolete information about participant" ;
  rdfs:subClassOf <http://www.geneontology.org/formats/oboInOwl#ObsoleteClass> .

obo:ICO_0000108 a rdfs:Class ;
  rdfs:label "withdrawing participation in study"@en ;
  rdfs:comment "A planned process in which an agent decides to discontinue further participation in a study."@en ;
  rdfs:subClassOf obo:OBI_0000011 .

obo:ICO_0000198 a rdfs:Class ;
  rdfs:label "specimen sharing directive"@en ;
  rdfs:comment "A directive information entity that prescribes whether, under what conditions, and with which recipients biospecimens (including human biological materials and their derivatives) may be shared beyond the original study team or repository." ;
  rdfs:subClassOf obo:IAO_0000033 .

obo:OBI_0002523 a rdfs:Class ;
  rdfs:label "breast specimen" ;
  rdfs:comment "A specimen that is derived from breast."@en ;
  rdfs:subClassOf obo:OBI_0001479 .

obo:DUO_0000017 a rdfs:Class ;
  rdfs:label "data use modifier"@en ;
  rdfs:comment "Data use modifiers indicate additional conditions for use."@en ;
  rdfs:subClassOf obo:IAO_0000027 .

obo:OBI_0002123 a rdfs:Class ;
  rdfs:label "IHC slide staining"@en ;
  rdfs:comment "A staining using labeled antibodies, i.e. the analytical part of immunohistochemistry. The staining is applied to fixed specimens on slides to identify biomarkers in tissues."@en ;
  rdfs:subClassOf obo:OBI_0302887 .

<http://purl.obolibrary.org/obo/ico.owl#Belongs_in_D-Acts> a rdfs:Class ;
  rdfs:label "obsolete ICO Classes to Move to D-Acts" ;
  rdfs:comment "This is a dummy class to be deprecated after it has fulfilled its organization purposes"@en ;
  rdfs:subClassOf <http://www.geneontology.org/formats/oboInOwl#ObsoleteClass> .

obo:IAO_0000017 a rdfs:Class ;
  rdfs:label "model number"@en ;
  rdfs:comment "A model number is an information content entity specifically borne by catalogs, design specifications, advertising materials, inventory systems and similar  that is about manufactured objects of the same class. The model number is an alternative term for the class. The manufactered objects may or may not also bear the model number. Model numbers can be encoded in a variety of other information objects, such as bar codes, numerals, or patterns of dots."@en ;
  rdfs:subClassOf obo:IAO_0000028 .

obo:OBI_0302884 a rdfs:Class ;
  rdfs:label "extraction"@en ;
  rdfs:comment "A material separation in which a desired component of an input material is separated from the remainder"@en ;
  rdfs:subClassOf obo:OBI_0600014 .

<http://semanticscience.org/resource/SIO_000184> a rdfs:Class ;
  rdfs:label "legal name"@en ;
  rdfs:comment "A legal name is a name given at birth, or which appears on their birth certificate, marriage certificate, or change of name certificate."@en ;
  rdfs:subClassOf obo:IAO_0000302 .

obo:BFO_0000029 a rdfs:Class ;
  rdfs:label "site"@en ;
  rdfs:subClassOf obo:BFO_0000141 .

obo:ICO_0000401 a rdfs:Class ;
  rdfs:label "designated authorized representative"@en ;
  rdfs:comment "A 'designated actor' that designates an authorized representative."@en ;
  rdfs:subClassOf obo:ICO_0000325 .

obo:ICO_0000142 a rdfs:Class ;
  rdfs:label "legally effective consenting"@en ;
  rdfs:comment "A planned process that results in a legally effective consent status."@en ;
  rdfs:subClassOf obo:OBI_0000011 .

obo:UO_0000003 a rdfs:Class ;
  rdfs:label "time unit" ;
  rdfs:comment "A unit which is a standard measure of the dimension in which events occur in sequence." ;
  rdfs:subClassOf obo:IAO_0000003 .

obo:ICO_0000099 a rdfs:Class ;
  rdfs:label "informed consent form for human urine biospecimen collection"@en ;
  rdfs:comment "An informed consent form designed for use in human urine collection."@en .

obo:IAO_0000706 a rdfs:Class ;
  rdfs:label "study bias section"@en ;
  rdfs:comment "A study limitations section that describes systematic error introduced into sampling or testing by selecting or encouraging one outcome or answer over others."@en ;
  rdfs:subClassOf obo:IAO_0000631 .

obo:DUO_0000006 a rdfs:Class ;
  rdfs:label "health or medical or biomedical research"@en ;
  rdfs:comment "This data use permission indicates that use is allowed for health/medical/biomedical purposes; does not include the study of population origins or ancestry."@en ;
  rdfs:subClassOf obo:DUO_0000042 .

obo:OBI_0000968 a rdfs:Class ;
  rdfs:label "device" ;
  rdfs:comment "A material entity that is designed to perform a function in a scientific investigation, but is not a reagent."@en ;
  rdfs:subClassOf obo:OBI_0000047 .

obo:UBERON_0001159 a rdfs:Class ;
  rdfs:label "sigmoid colon" ;
  rdfs:comment "The part of the large intestine that is closest to the rectum and anus. It forms a loop that averages about 40 cm. in length, and normally lies within the pelvis, but on account of its freedom of movement it is liable to be displaced into the abdominal cavity." ;
  rdfs:subClassOf obo:UBERON_0000465 .

obo:ICO_0000052 a rdfs:Class ;
  rdfs:label "obsolete metastatic melanoma research investigation" ;
  rdfs:comment "A cancer research investigation that specifically targets metastatic melanoma research."@en ;
  rdfs:subClassOf <http://www.geneontology.org/formats/oboInOwl#ObsoleteClass> .

obo:IAO_8000010 a rdfs:Class ;
  rdfs:label "exclusion subset ontology module"@en ;
  rdfs:comment "A subset of an ontology that is intended to be excluded for some purpose. For example, a blacklist of classes."@en ;
  rdfs:subClassOf obo:IAO_8000006 .

obo:OBI_2000016 a rdfs:Class ;
  rdfs:label "erythrocyte specimen" ;
  rdfs:comment "A specimen that is derived from some erythrocytes"@en ;
  rdfs:subClassOf obo:OBI_0001468 .

obo:IAO_0000320 a rdfs:Class ;
  rdfs:label "references section"@en ;
  rdfs:comment "A part of a document that has citations as parts"@en ;
  rdfs:subClassOf obo:IAO_0000314 .

obo:OBI_0002501 a rdfs:Class ;
  rdfs:label "bile specimen" ;
  rdfs:comment "A specimen that is derived from bile."@en ;
  rdfs:subClassOf obo:OBI_0002504 .

obo:OBI_0000965 a rdfs:Class ;
  rdfs:label "lyophilized specimen" ;
  rdfs:comment "a specimen that is output of a lyophilization storage process in which specimen is lyophilized for storage."@en ;
  rdfs:subClassOf obo:OBI_0001472 , obo:OBI_0100051 .

obo:OBI_0000453 a rdfs:Class ;
  rdfs:label "measure function"@en ;
  rdfs:comment "Measure function is a function that is borne by a processed material  and realized in a process in which information about some entity is expressed relative to some reference."@en ;
  rdfs:subClassOf obo:BFO_0000034 .

obo:CHMO_0002832 a rdfs:Class ;
  rdfs:label "material disposal" ;
  rdfs:comment "A planned process in which materials are removed permanently from the laboratory or repository." ;
  rdfs:subClassOf obo:CHMO_0002845 .

obo:OBI_0002783 a rdfs:Class ;
  rdfs:label "lower respiratory tract specimen" ;
  rdfs:comment "A specimen that is derived from the lower respiratory tract."@en ;
  rdfs:subClassOf obo:OBI_2000005 .

obo:OBI_1110046 a rdfs:Class ;
  rdfs:label "organ harvesting"@en ;
  rdfs:comment "The process of removing an organ from its source organism"@en ;
  rdfs:subClassOf obo:OBI_0600014 .

obo:ICO_0000294 a rdfs:Class ;
  rdfs:label "permission transfer directive"@en ;
  rdfs:comment "A directive information entity that prescribes the process of transferring a permission role from one bearer to another."@en ;
  rdfs:subClassOf obo:IAO_0000033 .

obo:OBI_0000908 a rdfs:Class ;
  rdfs:label "labeled DNA extract" ;
  rdfs:comment "a labeled specimen that is the output of a labeling process and has grain labeled DNA to be able to detect DNA in future experiments."@en ;
  rdfs:subClassOf obo:OBI_0001143 .

obo:IAO_0000303 a rdfs:Class ;
  rdfs:label "institutional identification"@en ;
  rdfs:comment "A textual entity intended to identify a particular institution"@en ;
  rdfs:subClassOf obo:IAO_0000300 .

obo:OBI_0000684 a rdfs:Class ;
  rdfs:label "specimen collection objective" ;
  rdfs:comment "A objective specification that is fulfilled by obtaining a material entity for potential use as an input upon which measurements or observations are performed."@en ;
  rdfs:subClassOf obo:IAO_0000005 .

obo:OBI_0000833 a rdf:Property ;
  rdfs:label "objective_achieved_by" ;
  rdfs:comment "This relation obtains between an objective specification and a planned process when the criteria specified in the objective specification are met at the end of the planned process."@en ;
  rdfs:domain obo:IAO_0000005 ;
  rdfs:range obo:OBI_0000011 .

obo:DUO_0000045 a rdfs:Class ;
  rdfs:label "not for profit organisation use only"@en ;
  rdfs:comment "This data use modifier indicates that use of the data is limited to not-for-profit organizations."@en ;
  rdfs:subClassOf obo:DUO_0000018 .

obo:OAE_0000001 a rdfs:Class ;
  rdfs:label "adverse event" ;
  rdfs:comment "a pathological bodily process that occurs after a medical intervention. An adverse event is likely caused by the medical intervention; however, such a causal association is not required to be an adverse event." ;
  rdfs:subClassOf obo:OGMS_0000060 .

obo:ICO_0000195 a rdfs:Class ;
  rdfs:label "act of permitting"@en ;
  rdfs:comment "A social act in which an agent bearing a deontic power role and realizes that role in the creation of a permission role."@en ;
  rdfs:subClassOf obo:IAO_0021009 .

obo:OBI_0001468 a rdfs:Class ;
  rdfs:label "cell specimen" ;
  rdfs:comment "A specimen primarily composed of a cell or cells collected from a multicellular organism or a cell culture."@en ;
  rdfs:subClassOf obo:OBI_0001479 .

obo:OBI_0002541 a rdfs:Class ;
  rdfs:label "spleen specimen" ;
  rdfs:comment "A specimen that is derived from spleen."@en ;
  rdfs:subClassOf obo:OBI_0001479 .

obo:DUO_0000011 a rdfs:Class ;
  rdfs:label "population origins or ancestry research only"@en ;
  rdfs:comment "This data use permission indicates that use of the data is limited to the study of population origins or ancestry."@en ;
  rdfs:subClassOf obo:DUO_0000001 .

obo:ICO_0000336 a rdfs:Class ;
  rdfs:label "designated process of unspecified use"@en ;
  rdfs:comment "A 'designated action' that designates a process unspecified use as permissable."@en ;
  rdfs:subClassOf obo:ICO_0000324 .

obo:OBI_0001404 a rdfs:Class ;
  rdfs:label "genetic characteristics information"@en ;
  rdfs:comment "a data item that is about genetic material including polymorphisms, disease alleles, and haplotypes."@en ;
  rdfs:subClassOf obo:IAO_0000027 .

obo:OBI_0600036 a rdfs:Class ;
  rdfs:label "establishing cell culture" ;
  rdfs:comment "a process through which a new type of cell culture or cell line is created, either through the isolation and culture of one or more cells from a fresh source, or the deliberate experimental modification of an existing cell culture (e.g passaging a primary culture to become a secondary culture or line, or the immortalization or stable genetic modification of an existing culture or line)."@en ;
  rdfs:subClassOf obo:OBI_0000094 .

obo:ICO_0000002 a rdfs:Class ;
  rdfs:label "designing an informed consent form"@en ;
  rdfs:comment "A planned process that involves the design of an informed consent form."@en ;
  rdfs:subClassOf obo:OBI_0000011 .

obo:NCBITaxon_33208 a rdfs:Class ;
  rdfs:label "Metazoa" ;
  rdfs:subClassOf obo:NCBITaxon_33154 .

obo:ICO_0000184 a rdfs:Class ;
  rdfs:label "obsolete NEW_CLASSES" ;
  rdfs:subClassOf <http://www.geneontology.org/formats/oboInOwl#ObsoleteClass> .

obo:OBI_2000009 a rdfs:Class ;
  rdfs:label "bodily fluid specimen" ;
  rdfs:comment "A specimen that is derived from some bodily fluid"@en ;
  rdfs:subClassOf obo:OBI_0001479 .

obo:OBI_0002537 a rdfs:Class ;
  rdfs:label "thyroid gland specimen" ;
  rdfs:comment "A specimen that is derived from thyroid gland."@en ;
  rdfs:subClassOf obo:OBI_0001479 .

obo:ICO_0000412 a rdfs:Class ;
  rdfs:label "designated age category research purpose"@en ;
  rdfs:comment "A 'designated biomedical research purpose' that designates a process of age category research as its end."@en ;
  rdfs:subClassOf obo:ICO_0000345 .

obo:ICO_0000257 a rdfs:Class ;
  rdfs:label "act of approving"@en ;
  rdfs:comment "A social act in which formal or official endorsement of some entity is communicated."@en ;
  rdfs:subClassOf obo:IAO_0021003 .

obo:GEO_000000400 a rdfs:Class ;
  rdfs:label "governmental organization"@en ;
  rdfs:comment "An organization that governs the people living in a particular geographical region or aggregate of geographical regions. The geographical region it governs can change over time (such as the westward expansion of the United States and the addition of Hawaii). Note: this definition was taken over from \"geopolitical organization\"."@en ;
  rdfs:subClassOf obo:OBI_0000245 .

obo:BFO_0000038 a rdfs:Class ;
  rdfs:label "one-dimensional temporal region"@en ;
  rdfs:subClassOf obo:BFO_0000008 .

obo:ICO_0000283 a rdfs:Class ;
  rdfs:label "description of financial risk"@en ;
  rdfs:comment "A description of risk that describes the magnitude of potential financial loss."@en ;
  rdfs:subClassOf <http://www.ontologyrepository.com/CommonCoreOntologies/DescriptiveInformationContentEntity> .

obo:IAO_0000630 a rdfs:Class ;
  rdfs:label "keywords section"@en ;
  rdfs:comment "A part of a document where keywords selected by the author to categorize the major theme(s) of a document are listed."@en ;
  rdfs:subClassOf obo:IAO_0000314 .

obo:IAO_0000314 a rdfs:Class ;
  rdfs:label "document part"@en ;
  rdfs:comment "An information content entity that is part of a document."@en ;
  rdfs:subClassOf obo:IAO_0000030 .

obo:ICO_0000083 a rdfs:Class ;
  rdfs:label "individually identifiable health information entity"@en ;
  rdfs:comment "A protected health information entity which identifies an individual; or with respect to which there is a reasonable basis to believe the information can be used to identify an individual."@en ;
  rdfs:subClassOf obo:ICO_0000103 .

obo:IAO_0000098 a rdfs:Class ;
  rdfs:label "data format specification"@en ;
  rdfs:comment """A data format specification is the information content borne by the document published defining the specification.
Example: The ISO document specifying what encompasses an XML document; The instructions in a XSD file"""@en ;
  rdfs:subClassOf obo:IAO_0000033 .

obo:ICO_0000204 a rdfs:Class ;
  rdfs:label "assenter"@en ;
  rdfs:comment "An agent who has communicated their assent."@en ;
  rdfs:subClassOf obo:ICO_0000220 .

obo:ICO_0000225 a rdf:Property ;
  rdfs:label "agent in"@en ;
  rdfs:comment "A relation between a continuant and a process, where the continuant is a causal participant in the process."@en ;
  rdfs:domain obo:BFO_0000002 ;
  rdfs:range obo:BFO_0000003 ;
  rdfs:subPropertyOf obo:RO_0000056 .

obo:APOLLO_SV_00000033 a rdfs:Class ;
  rdfs:label "counting"@en ;
  rdfs:comment "The planned process of finding the number of elements in a finite set of objects."@en ;
  rdfs:subClassOf obo:OBI_0000011 .

obo:ICO_0000272 a rdfs:Class ;
  rdfs:label "description of expected study participation duration"@en ;
  rdfs:subClassOf <http://www.ontologyrepository.com/CommonCoreOntologies/DescriptiveInformationContentEntity> .

obo:ICO_0000265 a rdfs:Class ;
  rdfs:label "act of archiving informed consent"@en ;
  rdfs:comment "A planned process of storing the document output of an 'act of consent' for future use."@en ;
  rdfs:subClassOf obo:OBI_0000011 .

obo:ICO_0000061 a rdfs:Class ;
  rdfs:label "informed consent form for genetic study"@en ;
  rdfs:comment "An informed consent form that is designed for use in genetic studies."@en .

obo:PATO_0001241 a rdfs:Class ;
  rdfs:label "physical object quality" ;
  rdfs:comment "A quality which inheres in a continuant." ;
  rdfs:subClassOf obo:BFO_0000019 .

obo:DUO_0000002 a rdfs:Class ;
  rdfs:label "obsolete consent code primary category" ;
  rdfs:comment "A categorical data item indicating the primary category the consent code belongs to according to Dyke et al. 2016." ;
  rdfs:subClassOf <http://www.geneontology.org/formats/oboInOwl#ObsoleteClass> .

obo:IAO_0000415 a rdfs:Class ;
  rdfs:label "hypothesis textual entity"@en ;
  rdfs:comment "A textual entity that expresses an assertion that is intended to be tested."@en ;
  rdfs:subClassOf obo:IAO_0000300 .

obo:ICO_0000415 a rdfs:Class ;
  rdfs:label "designated pharmaceutical object"@en ;
  rdfs:comment "A 'designated object' that designates a pharmaceutical object"@en ;
  rdfs:subClassOf obo:ICO_0000326 .

obo:DUO_0000036 a rdfs:Class ;
  rdfs:label "research control" ;
  rdfs:comment "An investigation concerning use of data as reference or control material." ;
  rdfs:subClassOf obo:OBI_0000066 .

obo:ICO_0000388 a rdfs:Class ;
  rdfs:label "designated funding organization"@en ;
  rdfs:comment "A 'designated organization' that designates a funding organization."@en ;
  rdfs:subClassOf obo:ICO_0000384 .

obo:OGMS_0000060 a rdfs:Class ;
  rdfs:label "bodily process" ;
  rdfs:subClassOf obo:BFO_0000015 .

<http://www.w3.org/2003/11/swrl#Variable> a rdfs:Class .

obo:ICO_0000066 a rdfs:Class ;
  rdfs:label "clinical trial title"@en ;
  rdfs:comment "An investigation title that designates a clinical trial study, briefly identifying the purpose or design of the investigation."@en ;
  rdfs:subClassOf obo:OBI_0001622 .

obo:ICO_0000072 a rdfs:Class ;
  rdfs:label "contact person in informed consent process"@en ;
  rdfs:comment "A person who can be contacted during an informed consent process."@en ;
  rdfs:subClassOf obo:NCBITaxon_9606 .

obo:UBERON_0001797 a rdfs:Class ;
  rdfs:label "vitreous humor" ;
  rdfs:comment "A transparent, semigelatinous substance that fills the cavity behind the crystalline lens of the eye and in front of the retina." ;
  rdfs:subClassOf obo:UBERON_0000463 .

obo:OBI_0002552 a rdfs:Class ;
  rdfs:label "testis specimen" ;
  rdfs:comment "A specimen that is derived from testis."@en ;
  rdfs:subClassOf obo:OBI_0001479 .

obo:OBI_0003415 a rdfs:Class ;
  rdfs:label "peripheral blood mononuclear cell specimen" ;
  rdfs:comment "A processed specimen that is extracted from whole blood using gradient centrifugation that separates the blood into a layer of peripheral blood mononuclear cells under the top layer of plasma. It contains lymphocytes, monocytes or macrophages that are critical components in the immune system."@en ;
  rdfs:subClassOf obo:OBI_0000655 .

obo:IAO_0000129 a rdfs:Class ;
  rdfs:label "version number"@en ;
  rdfs:comment "A version number is an information content entity which is a sequence of characters borne by part of each of a class of manufactured products or its packaging and indicates its order within a set of other products having the same name."@en ;
  rdfs:subClassOf obo:IAO_0000028 .

obo:IAO_0000178 a rdfs:Class ;
  rdfs:label "material information bearer"@en ;
  rdfs:comment "A material entity in which a concretization of an information content entity inheres."@en ;
  rdfs:subClassOf obo:BFO_0000040 .

obo:ICO_0000319 a rdfs:Class ;
  rdfs:label "investigator role directive"@en ;
  rdfs:comment "A role directive that prescribes the bearer of an investigator role in a process."@en ;
  rdfs:subClassOf obo:ICO_0000316 .

obo:UBERON_0002097 a rdfs:Class ;
  rdfs:label "skin of body" ;
  rdfs:comment "The organ covering the body that consists of the dermis and epidermis." ;
  rdfs:subClassOf obo:UBERON_0000465 .

obo:UBERON_0002391 a rdfs:Class ;
  rdfs:label "lymph" ;
  rdfs:comment "Lymph is the fluid that is formed when interstitial fluid enters the conduits of the lymphatic system through lymph capillaries[WP]." ;
  rdfs:subClassOf obo:UBERON_0006314 .

obo:ICO_0000290 a rdfs:Class ;
  rdfs:label "waiver document"@en ;
  rdfs:comment "A document designed for the purpose of assisting in an act of waiving, and which contains both some description of waiver and some waiver directive."@en ;
  rdfs:subClassOf obo:IAO_0000310 .

obo:UBERON_0001567 a rdfs:Class ;
  rdfs:label "cheek" ;
  rdfs:comment "A fleshy subdivision of one side of the face bounded by an eye, ear and the nose." ;
  rdfs:subClassOf obo:UBERON_0000465 .

obo:BFO_0000141 a rdfs:Class ;
  rdfs:label "immaterial entity"@en ;
  rdfs:subClassOf obo:BFO_0000004 .

obo:IAO_0000641 a rdfs:Class ;
  rdfs:label "requirements section"@en ;
  rdfs:comment "A part of a document about a resource described in the document, e.g. software, that describes the requirements necessary to use the resource, e.g. operating systems, hardware, etc. in the case of a software resource."@en ;
  rdfs:subClassOf obo:IAO_0000314 .

obo:UBERON_0000955 a rdfs:Class ;
  rdfs:label "brain" ;
  rdfs:comment "The brain is the center of the nervous system in all vertebrate, and most invertebrate, animals. Some primitive animals such as jellyfish and starfish have a decentralized nervous system without a brain, while sponges lack any nervous system at all. In vertebrates, the brain is located in the head, protected by the skull and close to the primary sensory apparatus of vision, hearing, balance, taste, and smell[WP]." ;
  rdfs:subClassOf obo:UBERON_0000465 .

obo:CL_0000738 a rdfs:Class ;
  rdfs:label "leukocyte" ;
  rdfs:comment "An achromatic cell of the myeloid or lymphoid lineages capable of ameboid movement, found in blood or other tissue." ;
  rdfs:subClassOf obo:CL_0000000 .

obo:ICO_0000332 a rdfs:Class ;
  rdfs:label "designated process of collection"@en ;
  rdfs:comment "A 'designated action' that designates a process of collection as permissable."@en ;
  rdfs:subClassOf obo:ICO_0000324 .

obo:NCBITaxon_2157 a rdfs:Class ;
  rdfs:label "Archaea" ;
  rdfs:subClassOf obo:OBI_0100026 .

obo:CL_0000010 a rdfs:Class ;
  rdfs:label "cultured cell" ;
  rdfs:comment "A cell in vitro that is or has been maintained or propagated as part of a cell culture." ;
  rdfs:subClassOf obo:CL_0000578 .

obo:ERO_0000333 a rdfs:Class ;
  rdfs:label "video"@en ;
  rdfs:comment "Data containing moving pictures stored in digital and analog formats."@en ;
  rdfs:subClassOf obo:IAO_0000098 .

obo:IAO_0000308 a rdfs:Class ;
  rdfs:label "figure"@en ;
  rdfs:comment "An information content entity consisting of a two dimensional arrangement of information content entities such that the arrangement itself is about something."@en ;
  rdfs:subClassOf obo:IAO_0000030 .

obo:ICO_0000399 a rdfs:Class ;
  rdfs:label "designated assenting actor"@en ;
  rdfs:comment "A 'designated actor' that designates the entity that is permitting some 'designated action'."@en ;
  rdfs:subClassOf obo:ICO_0000325 .

obo:ICO_0000160 a rdfs:Class ;
  rdfs:label "consenting in short form"@en ;
  rdfs:comment "An informed consent process in which the participant is not able to read and write in the language of the informed consent form, but is aided in understanding the informed consent process by a translation into the agent's native language."@en ;
  rdfs:subClassOf obo:OBI_0000810 .

obo:DUO_0000025 a rdfs:Class ;
  rdfs:label "time limit on use"@en ;
  rdfs:comment "This data use modifier indicates that use is approved for a specific number of months."@en ;
  rdfs:subClassOf obo:DUO_0000017 .

obo:UBERON_0001088 a rdfs:Class ;
  rdfs:label "urine" ;
  rdfs:comment "Excretion that is the output of a kidney." ;
  rdfs:subClassOf obo:UBERON_0000463 .

obo:IAO_0000576 a rdfs:Class ;
  rdfs:label "obsolete_establishing a CRID registry" ;
  rdfs:comment "a planned process with the objective to establish a system that allows to refer to specific entities of a certain kind and store information about them, by establishing a CRID registry and plan specifications for the process of 1) assigning a CRID and 2) looking up a CRID." ;
  rdfs:subClassOf <http://www.geneontology.org/formats/oboInOwl#ObsoleteClass> .

obo:OBI_0001898 a rdfs:Class ;
  rdfs:label "comment on investigation"@en ;
  rdfs:comment "A textual entity that is about any of the aspects of an investigation worth noting"@en ;
  rdfs:subClassOf obo:IAO_0000300 .

obo:IAO_0021300 a rdfs:Class ;
  rdfs:label "obligor role"@en ;
  rdfs:comment "A role that is either the specified output of an obligation generating social act or the concretization of a transferable obligation and that is realized by it's bearer being the receiving part of a process that fulfills the previously agreed upon requirements."@en ;
  rdfs:subClassOf obo:BFO_0000023 .

obo:IAO_0000327 a rdfs:Class ;
  rdfs:label "table of contents"@en ;
  rdfs:comment "A table that relates document parts to specific locations in a document (usually page numbers).  This is also a document part (subsumption there should be inferred)."@en ;
  rdfs:subClassOf obo:IAO_0000306 .

obo:OBI_0001305 a rdfs:Class ;
  rdfs:label "genotype information"@en ;
  rdfs:comment "a genetic characteristics information that is about the genetic material of an organism and minimally includes information about the genetic background and can in addition contain information about specific alleles, genetic modifications, etc."@en ;
  rdfs:subClassOf obo:OBI_0001404 .

obo:OBI_0002512 a rdfs:Class ;
  rdfs:label "bone marrow specimen" ;
  rdfs:comment "A specimen that is derived from bone marrow."@en ;
  rdfs:subClassOf obo:OBI_0001479 .

obo:ICO_0000200 a rdfs:Class ;
  rdfs:label "obsolete consent power role" ;
  rdfs:comment "A deontic power role that, if realized, may permit an Act of Consent and thereby create a permission role, or revoke or modify a previously provided permission role created by permitting an Act of Consent."@en ;
  rdfs:subClassOf <http://www.geneontology.org/formats/oboInOwl#ObsoleteClass> .

obo:OBI_0000450 a rdfs:Class ;
  rdfs:label "regulatory agency"@en ;
  rdfs:comment "A regulatory agency is a organization that has responsibility over or for  the legislation (acts and regulations) for a given sector of the government."@en ;
  rdfs:subClassOf obo:OBI_0000245 .

obo:ICO_0000171 a rdfs:Class ;
  rdfs:label "filled multiple choice text entity"@en ;
  rdfs:comment "A textual entity that is the recorded response to a multiple choice question."@en ;
  rdfs:subClassOf obo:IAO_0000300 .

obo:ICO_0000119 a rdfs:Class ;
  rdfs:label "obsolete storage duration of signed informed consent form" ;
  rdfs:subClassOf <http://www.geneontology.org/formats/oboInOwl#ObsoleteClass> .

obo:IAO_0000006 a rdfs:Class ;
  rdfs:label "narrative object"@en ;
  rdfs:comment "A narrative object is an information content entity that is a set of propositions."@en ;
  rdfs:subClassOf obo:IAO_0000030 .

obo:OBI_0003610 a rdfs:Class ;
  rdfs:label "reactant role"@en ;
  rdfs:comment "A role borne by a biological or chemical entity that participates or has molecular components that participate in a chemical reaction."@en ;
  rdfs:subClassOf obo:BFO_0000023 .

obo:IAO_0000028 a rdfs:Class ;
  rdfs:label "symbol"@en ;
  rdfs:comment "An information content entity that is a mark(s) or character(s) used as a conventional representation of another entity."@en ;
  rdfs:subClassOf obo:IAO_0000030 .

obo:IAO_8000007 a rdfs:Class ;
  rdfs:label "curation subset ontology module"@en ;
  rdfs:comment "A subset ontology that is intended as a whitelist for curators using the ontology. Such a subset will exclude classes that curators should not use for curation."@en ;
  rdfs:subClassOf obo:IAO_8000006 .

obo:ICO_0000187 a rdfs:Class ;
  rdfs:label "legal representative role"@en ;
  rdfs:comment "A deontic role, which may be realized in an Act of Consent, where the bearer of the legal representative role consents on behalf of a person who lacks the capability to provide consent."@en ;
  rdfs:subClassOf obo:BFO_0000023 .

obo:BFO_0000011 a rdfs:Class ;
  rdfs:label "spatiotemporal region"@en ;
  rdfs:subClassOf obo:BFO_0000003 .

obo:IAO_0000634 a rdfs:Class ;
  rdfs:label "notes section"@en ;
  rdfs:comment "A part of a document containing typically short notes about the document itself and/or the authors. Often the notes section contains subsections related to funding, competing interests, ethical approval, etc."@en ;
  rdfs:subClassOf obo:IAO_0000314 .

obo:ICO_0000094 a rdfs:Class ;
  rdfs:label "obsolete follow-up visit" ;
  rdfs:comment "The process by which information about the health status of an individual is obtained after a study has officially closed; an activity that continues something that has already begun or that repeats something that has already been done."@en ;
  rdfs:subClassOf <http://www.geneontology.org/formats/oboInOwl#ObsoleteClass> .

obo:BFO_0000040 a rdfs:Class ;
  rdfs:label "material entity"@en ;
  rdfs:comment "An independent continuant that is spatially extended whose identity is independent of that of other entities and can be maintained through time."@en ;
  rdfs:subClassOf obo:BFO_0000004 .

obo:OBI_0400168 a rdfs:Class ;
  rdfs:label "microtome" ;
  rdfs:comment "A microtome is a mechanical instrument used to cut biological specimens into very thin segments for further treatment (e.g. ISH) and ultimately microscopic or histologic examination. Most microtomes provide cooling facilities (cryo-microtome) and use a steel blade to cut a slice of defined thickness. Some are automatic, and some are driven by hand."@en ;
  rdfs:subClassOf obo:OBI_0000932 .

obo:OBI_0003482 a rdfs:Class ;
  rdfs:label "lymph specimen" ;
  rdfs:comment "A specimen that is derived from a portion of lymph collected from an organism."@en ;
  rdfs:subClassOf obo:OBI_2000009 .

obo:OBI_0001936 a rdfs:Class ;
  rdfs:label "molecular-labeled material" ;
  rdfs:comment "a material entity that is the specified output of an addition of molecular label process that aims to label some molecular target to allow for its detection in a detection of molecular label assay"@en ;
  rdfs:subClassOf obo:BFO_0000040 , obo:OBI_0000047 .

obo:IAO_0020021 a rdfs:Class ;
  rdfs:label "identity document"@en ;
  rdfs:comment "A document that denotes some identity and is concretized by the bearer of some credential role."@en ;
  rdfs:subClassOf obo:IAO_0000310 .

obo:OBI_0000927 a rdfs:Class ;
  rdfs:label "lyophilization storage" ;
  rdfs:comment "a storage process with input material entity and output freeze dried material for long time storage"@en ;
  rdfs:subClassOf obo:OBI_0302893 .

obo:ICO_0000007 a rdfs:Class ;
  rdfs:label "part of informed consent form"@en ;
  rdfs:comment "A document that is a part of an informed consent form."@en ;
  rdfs:subClassOf obo:IAO_0000314 .

obo:ICO_0000308 a rdfs:Class ;
  rdfs:label "description of waiver"@en ;
  rdfs:comment "A descriptive information content entity that describes a directive information content entity that can be ignored."@en ;
  rdfs:subClassOf <http://www.ontologyrepository.com/CommonCoreOntologies/DescriptiveInformationContentEntity> .

obo:OBI_0500027 a rdfs:Class ;
  rdfs:label "inclusion criterion"@en ;
  rdfs:comment "an inclusion criterion (rule) is_a *eligibility criterion*  which defines and states a condition which, if met, makes an entity suitable for a given task or participation in a given process. For instance, in a study protocol, inclusion criteria indicate the conditions that prospective subjects MUST meet to be eligible for participation in a study."@en ;
  rdfs:subClassOf obo:OBI_0500026 .

obo:PR_000003918 a rdfs:Class ;
  rdfs:label "albumin" ;
  rdfs:comment "A protein that is a translation product of the human ALB gene or a 1:1 ortholog thereof." ;
  rdfs:subClassOf obo:PR_000000001 .

obo:ICO_0000018 a rdfs:Class ;
  rdfs:label "informed consent form signed by human subject"@en ;
  rdfs:comment "An informed consent form that has been signed by a human subject"@en .

obo:IAO_0000402 a rdfs:Class ;
  rdfs:label "two dimensional cartesian spatial coordinate datum"@en ;
  rdfs:comment "A cartesion spatial coordinate datum that  uses two values to specify a position within a two dimensional spatial region"@en ;
  rdfs:subClassOf obo:IAO_0000400 .

obo:IAO_0000577 a rdfs:Class ;
  rdfs:label "centrally registered identifier symbol"@en ;
  rdfs:comment "A symbol that is part of a CRID and that is sufficient to look up a record from the CRID's registry."@en ;
  rdfs:subClassOf obo:IAO_0000028 .

obo:OBIB_0000623 a rdfs:Class ;
  rdfs:label "biobank organization"@en ;
  rdfs:comment "An organization bearing legal personality that owns or adminstrates a biobank."@en ;
  rdfs:subClassOf obo:OBI_0000245 .

obo:ICO_0000011 a rdfs:Class ;
  rdfs:label "required informed consent element"@en ;
  rdfs:comment "A document part of an informed consent form for which an answer is required in order to complete the form."@en ;
  rdfs:subClassOf obo:IAO_0000314 .

obo:UBERON_0002409 a rdfs:Class ;
  rdfs:label "pericardial fluid" ;
  rdfs:comment "Transudate contained in the pericardial cavity.[FMA]." ;
  rdfs:subClassOf obo:UBERON_0006314 .

obo:ICO_0000425 a rdfs:Class ;
  rdfs:label "data recipient role"@en ;
  rdfs:comment "A role which is realized in processes of data disclosure."@en ;
  rdfs:subClassOf obo:BFO_0000023 .

obo:ICO_0000110 a rdfs:Class ;
  rdfs:label "standard medical treatment"@en ;
  rdfs:comment "A treatment currently in wide use and approved by a regulatory body or health authority, considered to be effective in the treatment of a specific disease or condition."@en ;
  rdfs:subClassOf obo:OGMS_0000090 .

obo:ICO_0000249 a rdfs:Class ;
  rdfs:label "conditional obligation directive"@en ;
  rdfs:comment "A conditional specification that prescirbes an obligation, should some trigger condition obtain."@en ;
  rdfs:subClassOf obo:IAO_0000001 .

obo:ICO_0000281 a rdfs:Class ;
  rdfs:label "description of breach of confidentiality"@en ;
  rdfs:subClassOf <http://www.ontologyrepository.com/CommonCoreOntologies/DescriptiveInformationContentEntity> .

obo:UBERON_0001225 a rdfs:Class ;
  rdfs:label "cortex of kidney" ;
  rdfs:comment "Outer cortical portion of the kidney, between the renal capsule and the renal medulla." ;
  rdfs:subClassOf obo:UBERON_0000465 .

obo:OBI_0000747 a rdfs:Class ;
  rdfs:label "material sample" ;
  rdfs:comment "A material entity that has the material sample role"@en ;
  rdfs:subClassOf obo:OBI_0100051 .

obo:ICO_0000343 a rdfs:Class ;
  rdfs:label "designated process of transfer"@en ;
  rdfs:comment "A 'designated action' that designates a process of transferral of ownership permissable."@en ;
  rdfs:subClassOf obo:ICO_0000324 .

obo:ICO_0000255 a rdfs:Class ;
  rdfs:label "withdrawal from participation directive"@en ;
  rdfs:comment "A directive information entity that prescribes some process for withdraw from another planned process."@en ;
  rdfs:subClassOf obo:IAO_0000033 .

obo:ICO_0000383 a rdfs:Class ;
  rdfs:label "designated information system actor"@en ;
  rdfs:comment "A 'designated actor' that designates an information system."@en ;
  rdfs:subClassOf obo:ICO_0000325 .

obo:ICO_0000182 a rdfs:Class ;
  rdfs:label "obsolete consenting to the secondary use of EHR" ;
  rdfs:subClassOf <http://www.geneontology.org/formats/oboInOwl#ObsoleteClass> .

obo:ICO_0000165 a rdfs:Class ;
  rdfs:label "subject withdrawal with sample stored for limited time"@en ;
  rdfs:comment "A planned process that represents a study participant withdrawing from the study and agreeing to have the participant sample stored for a limited time period."@en ;
  rdfs:subClassOf obo:OBI_0000011 .

obo:ICO_0000148 a rdfs:Class ;
  rdfs:label "candidate ineligible for study role"@en ;
  rdfs:comment "A role inhering in a participant who does not meet all eligibility criteria defined within the study protocol."@en ;
  rdfs:subClassOf obo:BFO_0000023 .

obo:OBI_2000000 a rdfs:Class ;
  rdfs:label "uterine cervix specimen" ;
  rdfs:comment "A specimen that is derived from some uterine cervix"@en ;
  rdfs:subClassOf obo:OBI_0002553 .

obo:OBI_0000932 a rdfs:Class ;
  rdfs:label "material separation device" ;
  rdfs:comment "A device with a separation function realized in a planed process"@en ;
  rdfs:subClassOf obo:OBI_0000968 .

obo:ICO_0000070 a rdfs:Class ;
  rdfs:label "contact person for questions about research subject rights"@en ;
  rdfs:comment "A person who is the contact for questions about research subject right."@en ;
  rdfs:subClassOf obo:NCBITaxon_9606 .

obo:IAO_0021000 a rdfs:Class ;
  rdfs:label "obsolete_claim"@en ;
  rdfs:subClassOf <http://www.geneontology.org/formats/oboInOwl#ObsoleteClass> .

obo:APOLLO_SV_00000032 a rdfs:Class ;
  rdfs:label "count"@en ;
  rdfs:comment "A measurement datum that is the output of counting."@en ;
  rdfs:subClassOf obo:IAO_0000027 , obo:IAO_0000109 .

obo:OBI_0002519 a rdfs:Class ;
  rdfs:label "skeletal muscle tissue specimen" ;
  rdfs:comment "A specimen that is derived from skeletal muscle."@en ;
  rdfs:subClassOf obo:OBI_0001479 .

obo:ICO_0000384 a rdfs:Class ;
  rdfs:label "designated organization"@en ;
  rdfs:comment "A 'designated actor' that designates an organization."@en ;
  rdfs:subClassOf obo:ICO_0000325 .

obo:ICO_0000025 a rdfs:Class ;
  rdfs:label "effective date specification in informed consent form"@en ;
  rdfs:comment "A date specification in an informed consent form that specifies an effective date of an investigation."@en ;
  rdfs:subClassOf obo:ICO_0000022 .

obo:BFO_0000005 a rdfs:Class ;
  rdfs:label "obsolete dependent continuant"@en ;
  rdfs:comment "A continuant  that is either dependent on one or other independent continuant  bearers or inheres in or is borne by other entities."@en ;
  rdfs:subClassOf <http://www.geneontology.org/formats/oboInOwl#ObsoleteClass> .

obo:OBI_0000859 a rdfs:Class ;
  rdfs:label "cytoplasmic RNA extraction" ;
  rdfs:comment "A RNA extraction process in which the desired output material is RNA in the cytoplasm."@en ;
  rdfs:subClassOf obo:OBI_0666666 .

obo:OBI_0001506 a rdfs:Class ;
  rdfs:label "specimen with pre- or post-mortem status" ;
  rdfs:comment "A specimen that has been established to be taken from a live (pre-mortem) or dead (post-mortem) organism."@en ;
  rdfs:subClassOf obo:OBI_0001479 , obo:OBI_0100051 .

obo:OBI_0002556 a rdfs:Class ;
  rdfs:label "minimum age value specification"@en ;
  rdfs:comment "A value specifcation that specifies the youngest age when specifying an age range."@en ;
  rdfs:subClassOf obo:OBI_0001933 .

obo:IAO_0000105 a rdfs:Class ;
  rdfs:label "obsolete2_digital document"@en ;
  rdfs:comment "A digital document is a digital entity consisting of an electronic file which can be rendered into human-readable form by one or more computational applications.  The digital document does not refer to the information content of the document but to an instance of the file."@en ;
  rdfs:subClassOf <http://www.geneontology.org/formats/oboInOwl#ObsoleteClass> .

obo:OBI_0002743 a rdfs:Class ;
  rdfs:label "molecular label role"@en ;
  rdfs:comment "A reagent role inhering in a molecular entity intended to associate with some molecular target to serve as a proxy for the presence, abundance, or location of this target in a detection of molecular label assay."@en ;
  rdfs:subClassOf obo:OBI_0000086 .

obo:IAO_0000316 a rdfs:Class ;
  rdfs:label "introduction to a publication about an investigation"@en ;
  rdfs:comment "A part of a publication about an investigation that is about the objective specification (why the investigation is being done)"@en ;
  rdfs:subClassOf obo:IAO_0000314 .

obo:ICO_0000266 a rdfs:Class ;
  rdfs:label "contact method description"@en ;
  rdfs:comment "A descriptive information content entity that describes a method of some act of communicating."@en ;
  rdfs:subClassOf <http://www.ontologyrepository.com/CommonCoreOntologies/DescriptiveInformationContentEntity> .

obo:ICO_0000074 a rdfs:Class ;
  rdfs:label "authorization for release of confidential health information"@en ;
  rdfs:comment "An act of authorizing that is signed by a patient, or his legal representative, or clinical study participant for the use or disclosure of oral, written, or electronic form of confidential health information that identifies the individual and relates to the medical history, diagnosis, treatment, or prognosis of his condition."@en ;
  rdfs:subClassOf obo:ICO_0000046 .

obo:CL_0000000 a rdfs:Class ;
  rdfs:label "cell" ;
  rdfs:comment "A material entity of anatomical origin (part of or deriving from an organism) that has as its parts a maximally connected cell compartment surrounded by a plasma membrane." ;
  rdfs:subClassOf obo:BFO_0000040 .

obo:IAO_0000309 a rdfs:Class ;
  rdfs:label "diagram"@en ;
  rdfs:comment "A figure that expresses one or more propositions"@en ;
  rdfs:subClassOf obo:IAO_0000308 .

obo:BFO_0000027 a rdfs:Class ;
  rdfs:label "object aggregate"@en ;
  rdfs:subClassOf obo:BFO_0000040 .

obo:UBERON_0003126 a rdfs:Class ;
  rdfs:label "trachea" ;
  rdfs:comment "The trachea is the portion of the airway that attaches to the bronchi as it branches [GO:dph]." ;
  rdfs:subClassOf obo:UBERON_0000465 .

obo:IAO_0000100 a rdfs:Class ;
  rdfs:label "data set"@en ;
  rdfs:comment "A data item that is an aggregate of other data items of the same type that have something in common. Averages and distributions can be determined for data sets."@en ;
  rdfs:subClassOf obo:IAO_0000027 .

obo:IAO_8000002 a rdfs:Class ;
  rdfs:label "editors ontology module"@en ;
  rdfs:comment "An ontology module that is intended to be directly edited, typically managed in source control, and typically not intended for direct consumption by end-users."@en ;
  rdfs:subClassOf obo:IAO_8000000 .

obo:IAO_8000017 a rdfs:Class ;
  rdfs:label "ontology module subsetted by expressivity"@en ;
  rdfs:subClassOf obo:IAO_8000006 .

obo:ICO_0000244 a rdfs:Class ;
  rdfs:label "permission directive"@en ;
  rdfs:comment "A 'directive information entity' that prescribes an allowable action,  where that action is otherwise impermissible."@en ;
  rdfs:subClassOf obo:IAO_0000033 .

obo:ICO_0000050 a rdfs:Class ;
  rdfs:label "obsolete animal research investigation" ;
  rdfs:comment "An investigation that involves animal research."@en ;
  rdfs:subClassOf <http://www.geneontology.org/formats/oboInOwl#ObsoleteClass> .

obo:ICO_0000323 a rdfs:Class ;
  rdfs:label "assent directive"@en ;
  rdfs:comment "A 'permission directive' that prescribes some action that is made allowable by an assenting entity."@en ;
  rdfs:subClassOf obo:ICO_0000244 .

obo:OBI_0002504 a rdfs:Class ;
  rdfs:label "digestive system fluid or secretion specimen" ;
  rdfs:comment "A specimen that is derived from digestive system fluid or secretion."@en ;
  rdfs:subClassOf obo:OBI_2000009 .

obo:OBI_0001003 a rdfs:Class ;
  rdfs:label "agar stab storage" ;
  rdfs:comment "a storage process with input cell culture and agar and output agar stab for long time storage"@en ;
  rdfs:subClassOf obo:OBI_0302893 .

obo:IAO_0000572 a rdfs:Class ;
  rdfs:label "documenting"@en ;
  rdfs:comment "A planned process in which a document is created or added to by including the specified input in it."@en ;
  rdfs:subClassOf obo:OBI_0000011 .

obo:ICO_0000103 a rdfs:Class ;
  rdfs:label "protected health information entity"@en ;
  rdfs:comment "A health information entity which is created, received, stored, or transmitted by covered entities and their business associates in relation to the provision of healthcare, healthcare operations and payment for healthcare services."@en ;
  rdfs:subClassOf obo:ICO_0000101 .

obo:ICO_0000395 a rdfs:Class ;
  rdfs:label "designated research organization"@en ;
  rdfs:comment "A 'designated organization' that desginates a research organization."@en ;
  rdfs:subClassOf obo:ICO_0000384 .

obo:ICO_0000112 a rdfs:Class ;
  rdfs:label "data administration function"@en ;
  rdfs:comment "An organizational function that involves the areas of information systems and computer science; and that may be realized in planning, organizing, describing, and controlling data resources."@en ;
  rdfs:subClassOf obo:BFO_0000034 .

obo:UBERON_0013756 a rdfs:Class ;
  rdfs:label "venous blood" ;
  rdfs:comment "A blood that is part of a vein." ;
  rdfs:subClassOf obo:UBERON_0000178 .

obo:OBI_1110109 a rdfs:Class ;
  rdfs:label "target of material addition" ;
  rdfs:comment "A material entity that receives the addition of another material entity in an “adding a material entity into a target” process."@en ;
  rdfs:subClassOf obo:BFO_0000040 .

obo:ICO_0000222 a rdfs:Class ;
  rdfs:label "signature"@en ;
  rdfs:comment "An information content entity that is a handwritten depiction of a name."@en ;
  rdfs:subClassOf obo:IAO_0000030 .

obo:IAO_0000091 a rdfs:Class ;
  rdfs:label "obsolete_report element"@en ;
  rdfs:comment "A report element is a narrative object in which information is presented and consumed by a human being, and is part of a report. Examples of report elements are figure (dot plot), table, text portion (may include a movie or audio clip on a web page)."@en ;
  rdfs:subClassOf <http://www.geneontology.org/formats/oboInOwl#ObsoleteClass> .

obo:OBI_0003595 a rdfs:Class ;
  rdfs:label "nasal lavage fluid" ;
  rdfs:comment "A specimen collected through nasal cavity lavage that contains the reagents used to for the lavage process, organisms, cells, cellular secretions, and other biomaterials present in the nasal cavity space."@en ;
  rdfs:subClassOf obo:OBI_0003666 .

obo:UBERON_0001558 a rdfs:Class ;
  rdfs:label "lower respiratory tract" ;
  rdfs:comment "The segment of the respiratory tract that starts proximally with the trachea and includes all distal structures including the lungs[WP,modified]." ;
  rdfs:subClassOf obo:UBERON_0000465 .

obo:UBERON_0000992 a rdfs:Class ;
  rdfs:label "ovary" ;
  rdfs:comment "The gonad of a female organism which contains germ cells." ;
  rdfs:subClassOf obo:UBERON_0000465 .

obo:ICO_0000277 a rdfs:Class ;
  rdfs:label "description of collected information"@en ;
  rdfs:comment "A descriptive information content entity that describes information that may be collected or the processes of information collection."@en ;
  rdfs:subClassOf <http://www.ontologyrepository.com/CommonCoreOntologies/DescriptiveInformationContentEntity> .

obo:IAO_0000625 a rdfs:Class ;
  rdfs:label "future directions section"@en ;
  rdfs:comment "A part of a document detailing extensions of the described work that may be implemented at some future point in time."@en ;
  rdfs:subClassOf obo:IAO_0000314 .

obo:OBI_0001879 a rdfs:Class ;
  rdfs:label "reagent"@en ;
  rdfs:comment "A biological or chemical entity that bears a reagent role in virtue of it being intended for application in a scientific technique  to participate in (or have molecular parts that participate in) a chemical reaction that facilitates the generation of data about some distinct entity, or the generation of some distinct material specified output."@en ;
  rdfs:subClassOf obo:BFO_0000040 , obo:OBI_0000047 .

obo:BFO_0000023 a rdfs:Class ;
  rdfs:label "role"@en ;
  rdfs:comment "A realizable entity  the manifestation of which brings about some result or end that is not essential to a continuant  in virtue of the kind of thing that it is but that can be served or participated in by that kind of continuant  in some kinds of natural, social or institutional contexts."@en ;
  rdfs:subClassOf obo:BFO_0000017 .

obo:ICO_0000301 a rdfs:Class ;
  rdfs:label "act of abuse"@en ;
  rdfs:comment "A process of mistreating an entity such that the mistreated entity is harmed."@en ;
  rdfs:subClassOf obo:BFO_0000015 .

obo:OBI_0002455 a rdfs:Class ;
  rdfs:label "clinically relevant exposure inclusion criterion"@en ;
  rdfs:comment "An inclusion criterion that defines and states one or more clinically relevant histories of exposure of an entity, which, if met, makes the entity suitable for a given task or participation in a given process."@en ;
  rdfs:subClassOf obo:OBI_0500027 .

obo:OMRSE_00000038 a rdfs:Class ;
  rdfs:label "legal person role"@en ;
  rdfs:comment "A role borne by a human individual or by a collection of humans regarded as possessing rights and duties enforeable at law."@en ;
  rdfs:subClassOf obo:BFO_0000023 .

obo:OMRSE_00000054 a rdfs:Class ;
  rdfs:label "hospital role"@en ;
  rdfs:comment "A healthcare provider role that inheres in an organization and is realized by providing inpatient care."@en ;
  rdfs:subClassOf obo:OMRSE_00000015 .

obo:OBI_0600014 a rdfs:Class ;
  rdfs:label "material component separation"@en ;
  rdfs:comment "a material processing in which components of an input material become segregated in space"@en ;
  rdfs:subClassOf obo:OBI_0000094 .

obo:ICO_0000292 a rdfs:Class ;
  rdfs:label "study protocol"@en ;
  rdfs:comment "A protocol that is formal plan of a research activity, including the objective, rationale, design, materials, and methods for the conduct of the activity."@en ;
  rdfs:subClassOf obo:OBI_0000272 .

obo:ICO_0000238 a rdfs:Class ;
  rdfs:label "broad consent rule"@en ;
  rdfs:comment "A rule in an informed consent regulatory document that prescribes deontic roles that may be realized in an unspecified range of activities, or which is subject to few restrictions."@en ;
  rdfs:subClassOf obo:IAO_0000055 .

obo:ICO_0000031 a rdfs:Class ;
  rdfs:label "informed consent form for qualitative study"@en ;
  rdfs:comment "An informed consent form that is used for a qualitative study."@en .

obo:OBI_0000471 a rdfs:Class ;
  rdfs:label "study design execution" ;
  rdfs:comment "a planned process that carries out a study design" ;
  rdfs:subClassOf obo:OBI_0000011 .

obo:OMRSE_00002029 a rdfs:Class ;
  rdfs:label "education process"@en ;
  rdfs:comment "A planned process with an active participant who acquires mental representations of information content entities (ICEs), which had no previous mental representation in the cognitive system, and through repeated use or application of these ICEs either (1) becomes the bearer of a new instance of some type of capability, and the participant was not previously the bearer of that instance of that type of capability, (2) \"improves\" an existing capability as demonstrated through realization(s) of that capability, and/or (3) loses a capability whose realization is considered negative."@en ;
  rdfs:subClassOf obo:OBI_0000011 .

obo:OBI_0000838 a rdfs:Class ;
  rdfs:label "material maintenance" ;
  rdfs:comment "A planned process with the objective to maintain some or all of the characteristics of an input material over time."@en ;
  rdfs:subClassOf obo:OBI_0000011 .

obo:IAO_0000614 a rdfs:Class ;
  rdfs:label "case report textual entity"@en ;
  rdfs:comment "A textual entity that expresses a detailed account of a portion of the medical history for a specific patient."@en ;
  rdfs:subClassOf obo:IAO_0000300 .

obo:ICO_0000337 a rdfs:Class ;
  rdfs:label "designated process of modification"@en ;
  rdfs:comment "A 'designated action' that designates a process of modifcation as permissable."@en ;
  rdfs:subClassOf obo:ICO_0000324 .

obo:OBI_0000977 a rdfs:Class ;
  rdfs:label "paraffin storage" ;
  rdfs:comment "a storage process with input organism or anatomical entity and paraffin and output material embedded in paraffin for long term storage"@en ;
  rdfs:subClassOf obo:OBI_0302893 .

obo:PATO_0001422 a rdfs:Class ;
  rdfs:label "dead" ;
  rdfs:comment "A viability quality inhering in a bearer by virtue of the cessation of the bearer's life." ;
  rdfs:subClassOf obo:PATO_0000169 .

obo:IAO_0000131 a rdfs:Class ;
  rdfs:label "serial number"@en ;
  rdfs:comment "A serial number is an information content entity which is a unique sequence of characters borne by part of manufactured product or its packaging that is assigned to each individual in some class of products, and so can serve as a way to identify an individual product within the class. Serial numbers can be encoded in a variety of other information objects, such as bar codes, numerals, or patterns of dots."@en ;
  rdfs:subClassOf obo:IAO_0000028 .

obo:OBI_0002561 a rdfs:Class ;
  rdfs:label "sex inclusion criterion"@en ;
  rdfs:comment "An inclusion criterion that defines and states one or more sexes which, if met, makes an entity suitable for a given task or participation in a given process."@en ;
  rdfs:subClassOf obo:OBI_0500027 .

obo:ICO_0000251 a rdfs:Class ;
  rdfs:label "description of medical procedure"@en ;
  rdfs:comment "A descriptive information content entity that describes a medical procedure."@en ;
  rdfs:subClassOf <http://www.ontologyrepository.com/CommonCoreOntologies/DescriptiveInformationContentEntity> .

obo:ICO_0000134 a rdfs:Class ;
  rdfs:label "explaining study derived data usage to participant candidate"@en ;
  rdfs:comment "In the case of promoting future data sharing, the usage of the data derived from a study is to be explained to the candidate."@en ;
  rdfs:subClassOf obo:ICO_0000154 .

obo:ICO_0000299 a rdfs:Class ;
  rdfs:label "protection directive"@en ;
  rdfs:comment "A trigger condition directive that prescribes conditions for which a individual bears a vulnerability role or disposition of vulnerability, or a population of such individuals."@en ;
  rdfs:subClassOf obo:ICO_0000252 .

obo:ICO_0000121 a rdfs:Class ;
  rdfs:label "explaining benefits of participation to participant candidate"@en ;
  rdfs:comment "The potential benefit to the study subject that may arise from participating the study research is to be explained to candidate"@en ;
  rdfs:subClassOf obo:ICO_0000154 .

obo:ICO_0000173 a rdfs:Class ;
  rdfs:label "no answer text entity"@en ;
  rdfs:comment "A filled multiple choice text entity that records a response indicating 'no' to a multiple choice question."@en ;
  rdfs:subClassOf obo:ICO_0000171 .

obo:ICO_0000154 a rdfs:Class ;
  rdfs:label "explaining to participant candidate in informed consent process"@en ;
  rdfs:comment "A planned process of communicating information about an informed consent process."@en ;
  rdfs:subClassOf obo:OBI_0000011 .

obo:ICO_0000378 a rdfs:Class ;
  rdfs:label "designated permitted actor"@en ;
  rdfs:comment "A 'designated actor' that designates an actor that may bear a permission role that may be realized in the process prescribed by the process designated by the 'designated action.'"@en ;
  rdfs:subClassOf obo:ICO_0000325 .

obo:OBI_0000651 a rdfs:Class ;
  rdfs:label "urine specimen" ;
  rdfs:comment "a portion of urine collected from an organism"@en ;
  rdfs:subClassOf obo:OBI_2000009 .

obo:IAO_8000013 a rdfs:Class ;
  rdfs:label "reasoned ontology module"@en ;
  rdfs:comment "An ontology module that contains axioms generated by a reasoner. The generated axioms are typically direct SubClassOf axioms, but other possibilities are available."@en ;
  rdfs:seeAlso <http://robot.obolibrary.org/reason> ;
  rdfs:subClassOf obo:IAO_8000000 .

obo:IAO_0000644 a rdfs:Class ;
  rdfs:label "statistical analysis section"@en ;
  rdfs:comment "A part of the document used to describe the statistical methodologies employed in the work presented in the document."@en ;
  rdfs:subClassOf obo:IAO_0000314 .

obo:IAO_0000180 a rdfs:Class ;
  rdfs:label "heatmap"@en ;
  rdfs:comment """A heatmap is a report graph which is a graphical representation of data
where the values taken by a variable(s) are shown as colors in a
two-dimensional map."""@en ;
  rdfs:subClassOf obo:IAO_0000038 .

obo:OBI_0001051 a rdfs:Class ;
  rdfs:label "DNA extract" ;
  rdfs:comment "The output of an extraction process in which DNA molecules are purified in order to exclude DNA from organellas."@en ;
  rdfs:subClassOf obo:OBI_0001010 .

obo:ICO_0000312 a rdfs:Class ;
  rdfs:label "genetic testing directive"@en ;
  rdfs:comment "A directive information entity that prescribes some act of genetic testing."@en ;
  rdfs:subClassOf obo:IAO_0000033 .

obo:OBI_0002608 a rdfs:Class ;
  rdfs:label "oropharyngeal swab specimen" ;
  rdfs:comment "A specimen that is collected with a swab from the surface of a oropharynx."@en ;
  rdfs:subClassOf obo:OBI_0002599 , obo:OBI_2000006 .

obo:IAO_0000330 a rdfs:Class ;
  rdfs:label "copyright section"@en ;
  rdfs:comment "A document part that describes  legal restrictions on making or distributing copies of the document"@en ;
  rdfs:subClassOf obo:IAO_0000314 .

obo:IAO_0000705 a rdfs:Class ;
  rdfs:label "research settings section"@en ;
  rdfs:comment "A document part that describes the physical/social/cultural conditions around a research trial."@en ;
  rdfs:subClassOf obo:IAO_0000314 .

obo:BFO_0000016 a rdfs:Class ;
  rdfs:label "disposition"@en ;
  rdfs:subClassOf obo:BFO_0000017 .

obo:ICO_0000347 a rdfs:Class ;
  rdfs:label "designated administrative purpose"@en ;
  rdfs:comment "A 'permission purpose directive' that designates a process relating to the management of an organization as its end."@en ;
  rdfs:subClassOf obo:ICO_0000328 .

obo:IAO_0000611 a rdfs:Class ;
  rdfs:label "availability section"@en ;
  rdfs:comment "A part of a document about a resource described in the document, e.g. software, that describes where and/or how that resource can be obtained."@en ;
  rdfs:subClassOf obo:IAO_0000314 .

obo:OBI_0100067 a rdfs:Class ;
  rdfs:label "bronchial alveolar lavage" ;
  rdfs:comment "Group of biomaterials present in the bronchial aveolar space of an organism which are collected through lavage including the reagents used to for the lavage process, organisms, cells, and cellular secretions present in the bronchial aveolar space."@en ;
  rdfs:subClassOf obo:OBI_0003666 .

obo:UBERON_0007650 a rdfs:Class ;
  rdfs:label "esophagogastric junction" ;
  rdfs:comment "The junction between the esophagus and the stomach epithelium." ;
  rdfs:subClassOf obo:UBERON_0000465 .

obo:ICO_0000085 a rdfs:Class ;
  rdfs:label "informed assent form"@en ;
  rdfs:comment "A document that explains relevant information regarding the expectations and requirements of participation in a research study or clinical procedure, is adapted to the cognitive capacities of that individual so as to assist in that individual's understanding, and is designed to record the assent of that individual."@en ;
  rdfs:subClassOf obo:IAO_0000310 .

obo:OBI_0002515 a rdfs:Class ;
  rdfs:label "pleural fluid specimen" ;
  rdfs:comment "A specimen that is derived from pleural fluid."@en ;
  rdfs:subClassOf obo:OBI_2000009 .

<http://www.ontologyrepository.com/CommonCoreOntologies/DesignativeInformationContentEntity> a rdfs:Class ;
  rdfs:label "Designative Information Content Entity"@en ;
  rdfs:comment "An Information Content Entity that consists of a set of symbols that denote some Entity."@en ;
  rdfs:subClassOf obo:IAO_0000030 .

obo:UBERON_0001637 a rdfs:Class ;
  rdfs:label "artery" ;
  rdfs:comment "An epithelial tube or tree of tibes that transports blood away from the heart[modified from AEO definition]." ;
  rdfs:subClassOf obo:UBERON_0000465 .

obo:UBERON_0000165 a rdfs:Class ;
  rdfs:label "mouth" ;
  rdfs:comment "The proximal portion of the digestive tract, containing the oral cavity and bounded by the oral opening. In vertebrates, this extends to the pharynx and includes gums, lips, tongue and parts of the palate. Typically also includes the teeth, except where these occur elsewhere (e.g. pharyngeal jaws) or protrude from the mouth (tusks)." ;
  rdfs:subClassOf obo:UBERON_0000465 .

obo:OBI_0002534 a rdfs:Class ;
  rdfs:label "lung specimen" ;
  rdfs:comment "A specimen that is derived from lung."@en ;
  rdfs:subClassOf obo:OBI_0002783 .

obo:OBI_0000370 a rdfs:Class ;
  rdfs:label "contain function"@en ;
  rdfs:comment "A contain function is a function to constrain a material entities location in space"@en ;
  rdfs:subClassOf obo:BFO_0000034 .

obo:ICO_0000233 a rdfs:Class ;
  rdfs:label "regulatory document"@en ;
  rdfs:comment "A document that either prescribes actions or prescribes the permissions, obligations, restrictions, or protections relating to public or legal policy."@en ;
  rdfs:subClassOf obo:IAO_0000310 .

obo:ICO_0000270 a rdfs:Class ;
  rdfs:label "obsolete benefit" ;
  rdfs:subClassOf <http://www.geneontology.org/formats/oboInOwl#ObsoleteClass> .

obo:ICO_0000406 a rdfs:Class ;
  rdfs:label "designated methods development purpose"@en ;
  rdfs:comment "A 'designated research purpose' that designates a process of methods development research as it's end."@en ;
  rdfs:subClassOf obo:ICO_0000344 .

obo:IAO_0000636 a rdfs:Class ;
  rdfs:label "patients textual entity"@en ;
  rdfs:comment "A textual entity expressing information regarding the patients used in a study."@en ;
  rdfs:subClassOf obo:IAO_0000300 .

obo:OBI_0000272 a rdfs:Class ;
  rdfs:label "protocol"@en ;
  rdfs:comment "A plan specification which has sufficient level of detail and quantitative information to communicate it between investigation agents, so that different investigation agents will reliably be able to independently reproduce the process."@en ;
  rdfs:subClassOf obo:IAO_0000104 .

obo:UBERON_0007106 a rdfs:Class ;
  rdfs:label "chorionic villus" ;
  rdfs:comment "One of the minute vascular projections of the fetal chorion that combines with maternal uterine tissue to form the placenta." ;
  rdfs:subClassOf obo:UBERON_0000465 .

obo:ICO_0000328 a rdfs:Class ;
  rdfs:label "permission purpose directive"@en ;
  rdfs:comment "A 'permission condition directive' that directs the purpose for a 'permission directive'."@en ;
  rdfs:subClassOf obo:ICO_0000357 .

obo:IAO_0000030 a rdfs:Class ;
  rdfs:label "information content entity"@en ;
  rdfs:comment "A generically dependent continuant that is about some thing."@en ;
  rdfs:subClassOf obo:BFO_0000031 .

obo:ICO_0000369 a rdfs:Class ;
  rdfs:label "designated genetic data"@en ;
  rdfs:comment "A 'designated data' that designates genetic data."@en ;
  rdfs:subClassOf obo:ICO_0000367 .

obo:OBI_0000341 a rdfs:Class ;
  rdfs:label "histological sample preparation"@en ;
  rdfs:comment "histological sample preparation is the preparation of an input tissue via slicing and labeling to make tissue microstructure of interest visible in a future histology assay"@en ;
  rdfs:subClassOf obo:OBI_0000094 , obo:OBI_0000659 .

obo:UBERON_0001090 a rdfs:Class ;
  rdfs:label "synovial fluid" ;
  rdfs:comment "Joint fluid is a transudate of plasma that is actively secreted by synovial cells." ;
  rdfs:subClassOf obo:UBERON_0006314 .

obo:ICO_0000422 a rdfs:Class ;
  rdfs:label "patient"@en ;
  rdfs:comment "An agent who bears a patient role."@en ;
  rdfs:subClassOf obo:NCBITaxon_9606 .

obo:RO_0000053 a rdf:Property ;
  rdfs:label "has characteristic"@en ;
  rdfs:comment "a relation between an independent continuant (the bearer) and a specifically dependent continuant (the dependent), in which the dependent specifically depends on the bearer for its existence"@en ;
  rdfs:range obo:BFO_0000020 .

obo:OBI_0002612 a rdfs:Class ;
  rdfs:label "fecal swab specimen" ;
  rdfs:comment "A specimen that is collected with a swab from the surface of a feces."@en ;
  rdfs:subClassOf obo:OBI_0002503 , obo:OBI_0002599 .

obo:ICO_0000006 a rdfs:Class ;
  rdfs:label "informed consent regulatory body"@en ;
  rdfs:comment "An organization charged with approving clinical study protocols and ensuring that applicable governing rules and laws are upheld."@en ;
  rdfs:subClassOf obo:OBI_0000245 .

obo:IAO_0000442 a rdfs:Class ;
  rdfs:label "author role"@en ;
  rdfs:comment "A role inhering in a person or organization that is realized when the bearer participates in the work which is the basis of the document, in the writing of the document, and signs it with their name."@en ;
  rdfs:subClassOf obo:BFO_0000023 .

obo:PATO_0001995 a rdfs:Class ;
  rdfs:label "organismal quality" ;
  rdfs:comment "A quality that inheres in an entire organism or part of an organism." ;
  rdfs:subClassOf obo:PATO_0001241 .

obo:OBI_0000740 a rdfs:Class ;
  rdfs:label "material sample role" ;
  rdfs:comment "A material sample role is a specimen role borne by a material entity that is the output of a material sampling process."@en ;
  rdfs:subClassOf obo:OBI_0000112 .

obo:ICO_0000288 a rdfs:Class ;
  rdfs:label "pregnant woman"@en ;
  rdfs:comment "A woman who is pregnant."@en ;
  rdfs:subClassOf obo:BFO_0000030 .

obo:OBI_0002453 a rdfs:Class ;
  rdfs:label "health status inclusion criterion"@en ;
  rdfs:comment "An inclusion criterion that defines and states one or more clinically significant bodily components, dispositions, and/or bodily processes of an entity that are inferred from relevant clinical findings or self-reported, which, if met, makes the entity suitable for a given task or participation in a given process."@en ;
  rdfs:subClassOf obo:OBI_0500027 .

obo:PATO_0000122 a rdfs:Class ;
  rdfs:label "length" ;
  rdfs:comment "A 1-D extent quality which is equal to the distance between two points." ;
  rdfs:subClassOf obo:PATO_0000051 .

obo:OBI_0001912 a rdfs:Class ;
  rdfs:label "cell freezing medium"@en ;
  rdfs:comment "A processed material that serves as a liquid vehicle for freezing cells for long term quiescent stroage, which contains chemicls needed to sustain cell viability across freeze-thaw cycles."@en ;
  rdfs:subClassOf obo:OBI_0000047 .

obo:IAO_0000633 a rdfs:Class ;
  rdfs:label "materials section"@en ;
  rdfs:comment "A part of a document about the materials required to reproduce the content of the document."@en ;
  rdfs:subClassOf obo:IAO_0000314 .

obo:ICO_0000227 a rdfs:Class ;
  rdfs:label "act of storing"@en ;
  rdfs:comment "A planned process that involves placing a material entity in some location in order to maintain possession of it."@en ;
  rdfs:subClassOf obo:OBI_0000011 .

obo:ICO_0000063 a rdfs:Class ;
  rdfs:label "obsolete informed consent form for quantitative study" ;
  rdfs:subClassOf <http://www.geneontology.org/formats/oboInOwl#ObsoleteClass> .

obo:ICO_0000176 a rdfs:Class ;
  rdfs:label "obsolete permittee deontic role" ;
  rdfs:comment "A deontic role that if realized is realized by its bearer conducting or overseeing genetic research on the genome of a human donor."@en ;
  rdfs:subClassOf <http://www.geneontology.org/formats/oboInOwl#ObsoleteClass> .

obo:ICO_0000240 a rdfs:Class ;
  rdfs:label "deontic power role directive"@en ;
  rdfs:comment "A directive information entity that prescribes a deontic power role or the process that realizes it."@en ;
  rdfs:subClassOf obo:IAO_0000033 .

obo:OBI_0000103 a rdfs:Class ;
  rdfs:label "principal investigator role"@en ;
  rdfs:comment "a responsible party role played by a person responsible for the overall conduct of a study"@en ;
  rdfs:subClassOf obo:OBI_0000102 .

obo:NCBITaxon_7742 a rdfs:Class ;
  rdfs:label "Vertebrata <vertebrates>" ;
  rdfs:subClassOf obo:NCBITaxon_33213 .

obo:ICO_0000036 a rdfs:Class ;
  rdfs:label "informed consent form signing date" ;
  rdfs:comment "A date specification that designates when an informed consent form was signed."@en ;
  rdfs:subClassOf obo:ICO_0000022 .

obo:ENVO_00010483 a rdfs:Class ;
  rdfs:label "environmental material" ;
  rdfs:comment "A material entity which other material entities in an environmental system are primarily or partially composed of."@en ;
  rdfs:subClassOf obo:BFO_0000040 .

obo:ICO_0000159 a rdfs:Class ;
  rdfs:label "informed verbal consent"@en ;
  rdfs:comment "An informed consent process in which the participant communicates consent orally rather than by filling out and signing a written form."@en ;
  rdfs:subClassOf obo:ICO_0000196 .

obo:OBI_0002508 a rdfs:Class ;
  rdfs:label "sputum specimen" ;
  rdfs:comment "A specimen that is derived from sputum."@en ;
  rdfs:subClassOf obo:OBI_2000009 .

obo:IAO_0021022 a rdfs:Class ;
  rdfs:label "deontic declaration performer role"@en ;
  rdfs:comment "A role inhering in a human being or an organization or an aggregate of any of the aforementioned that is realized by the bearer being the agent in a declaration."@en ;
  rdfs:subClassOf obo:BFO_0000023 .

obo:UBERON_0001268 a rdfs:Class ;
  rdfs:label "peritoneal fluid" ;
  rdfs:comment "Transudate contained in the peritoneal cavity." ;
  rdfs:subClassOf obo:UBERON_0006314 .

obo:OBI_0002433 a rdfs:Class ;
  rdfs:label "history of sex with someone with a history of intravenous drugs exclusion criterion" ;
  rdfs:comment "An exclusion criterion defined  as whether an individual has a history of sex with someone who has used intravenous drugs in a specified time frame, which if met, makes the individual unsuitable for a given task or participation in a given process."@en ;
  rdfs:subClassOf obo:OBI_0500028 .

obo:IAO_0000622 a rdfs:Class ;
  rdfs:label "figures section"@en ;
  rdfs:comment "A part of a document that contains one or more figures."@en ;
  rdfs:subClassOf obo:IAO_0000314 .

obo:IAO_8000006 a rdfs:Class ;
  rdfs:label "subset ontology module"@en ;
  rdfs:comment "An ontology module that is extracted from a main ontology module and includes only a subset of entities or axioms."@en ;
  rdfs:seeAlso <http://robot.obolibrary.org/filter> , <http://www.geneontology.org/page/go-slim-and-subset-guide> ;
  rdfs:subClassOf obo:IAO_8000000 .

obo:UBERON_0000996 a rdfs:Class ;
  rdfs:label "vagina" ;
  rdfs:comment "A fibromuscular tubular tract leading from the uterus to the exterior of the body in female placental mammals and marsupials, or to the cloaca in female birds, monotremes, and some reptiles[WP]." ;
  rdfs:subClassOf obo:UBERON_0000465 .

obo:OBI_0002627 a rdfs:Class ;
  rdfs:label "ribosomal RNA-depleted RNA extract" ;
  rdfs:comment "An extract of RNA which is produced through rRNA (ribosomal RNA) depletion (the removal of highly abundant rRNA species)."@en ;
  rdfs:subClassOf obo:OBI_0000880 .

obo:ICO_0000218 a rdfs:Class ;
  rdfs:label "act of removing identifiable information"@en ;
  rdfs:comment "An act of anonymization that alters an information content entity by removing information content which identifies that individual."@en ;
  rdfs:subClassOf obo:ICO_0000217 .

obo:IAO_0000325 a rdfs:Class ;
  rdfs:label "footnote"@en ;
  rdfs:comment "A part of a document that is about a specific other part of the document.  Usually footnotes are spatially segregated from the rest of the document."@en ;
  rdfs:subClassOf obo:IAO_0000314 .

obo:ICO_0000417 a rdfs:Class ;
  rdfs:label "designated return of results purpose"@en ;
  rdfs:comment "A 'permission purpose directive' that designates a return of results."@en ;
  rdfs:subClassOf obo:ICO_0000328 .

obo:ICO_0000047 a rdfs:Class ;
  rdfs:label "human population"@en ;
  rdfs:comment "A population of human beings."@en ;
  rdfs:subClassOf obo:OBI_0000181 .

obo:OBI_0002460 a rdfs:Class ;
  rdfs:label "defined population inclusion criterion"@en ;
  rdfs:comment "An inclusion criterion that is based on fitting within the defined characteristics of a population based study design."@en ;
  rdfs:subClassOf obo:OBI_0500027 .

obo:OMIABIS_0000050 a rdfs:Class ;
  rdfs:label "fixed tissue specimen"@en ;
  rdfs:comment "A processed specimen that is the output of a fixation process."@en ;
  rdfs:subClassOf obo:OBI_0000953 .

obo:OBI_0002545 a rdfs:Class ;
  rdfs:label "ileum specimen" ;
  rdfs:comment "A specimen that is derived from ileum."@en ;
  rdfs:subClassOf obo:OBI_0003483 .

obo:ICO_0000226 a rdfs:Class ;
  rdfs:label "stasis of anonymization"@en ;
  rdfs:comment "A stasis of generically dependent continuant that has participant some information content entity which, during the stasis, is unable to be used to identify some agent which the information is about."@en ;
  rdfs:subClassOf <http://www.ontologyrepository.com/CommonCoreOntologies/StasisOfGenericallyDependentContinuant> .

obo:UBERON_0000477 a rdfs:Class ;
  rdfs:label "anatomical cluster" ;
  rdfs:comment "Anatomical group whose component anatomical structures lie in close proximity to each other." ;
  rdfs:subClassOf obo:BFO_0000040 .

obo:OBI_2000008 a rdfs:Class ;
  rdfs:label "semen specimen" ;
  rdfs:comment "A specimen that is derived from some semen"@en ;
  rdfs:subClassOf obo:OBI_2000009 .

obo:ICO_0000295 a rdfs:Class ;
  rdfs:label "future use directive"@en ;
  rdfs:comment "A directive information entity that prescribes the processes that involve some entity as a participant."@en ;
  rdfs:subClassOf obo:IAO_0000033 .

obo:ICO_0000022 a rdfs:Class ;
  rdfs:label "temporal region identifier"@en ;
  rdfs:comment "A information content entity that designates a temporal region."@en ;
  rdfs:subClassOf obo:IAO_0000030 .

obo:ICO_0000197 a rdfs:Class ;
  rdfs:label "act of communicating assent"@en ;
  rdfs:comment "An act of communicating one’s agreement."@en ;
  rdfs:subClassOf obo:IAO_0021003 .

obo:OBI_0000017 a rdfs:Class ;
  rdfs:label "regulatory role"@en ;
  rdfs:comment "a role which inheres in material entities and is realized in the processes of making, enforcing or being defined by legislation or orders issued by a governmental body."@en ;
  rdfs:subClassOf obo:BFO_0000023 .

obo:BFO_0000026 a rdfs:Class ;
  rdfs:label "one-dimensional spatial region"@en ;
  rdfs:subClassOf obo:BFO_0000006 .

obo:NCBITaxon_9606 a rdfs:Class ;
  rdfs:label "Homo sapiens" ;
  rdfs:subClassOf obo:ICO_0000220 , obo:NCBITaxon_314146 .

obo:IAO_0000607 a rdfs:Class ;
  rdfs:label "author information section"@en ;
  rdfs:comment "A part of a document about the authors that provides biographical information and may discuss how the authors' professional experiences are relevant to the work described in the document."@en ;
  rdfs:subClassOf obo:IAO_0000314 .

obo:IAO_0000301 a rdfs:Class ;
  rdfs:label "citation"@en ;
  rdfs:comment "A textual entity intended to identify a particular publication."@en ;
  rdfs:subClassOf obo:IAO_0000300 .

obo:DUO_0000033 a rdfs:Class ;
  rdfs:label "ancestry research" ;
  rdfs:comment "An investigation concerning ancestry or population origins." ;
  rdfs:subClassOf obo:OBI_0000066 .

obo:ICO_0000302 a rdfs:Class ;
  rdfs:label "act of disclosure"@en ;
  rdfs:comment "An act of communicating in which information is shared, overriding or violating a judgment that the information should not be shared."@en ;
  rdfs:subClassOf obo:ICO_0000269 .

obo:OBI_0002551 a rdfs:Class ;
  rdfs:label "suprapubic skin specimen" ;
  rdfs:comment "A specimen that is derived from suprapubic skin."@en ;
  rdfs:subClassOf obo:OBI_0002526 .

obo:ICO_0000428 a rdfs:Class ;
  rdfs:label "ownership statis"@en ;
  rdfs:comment "A stasis in which an entity bears an ownership role."@en ;
  rdfs:subClassOf <http://www.ontologyrepository.com/CommonCoreOntologies/Stasis> .

obo:IAO_0000618 a rdfs:Class ;
  rdfs:label "consent section"@en ;
  rdfs:comment "A part of a document about the consent process that was used to enroll patients in a study."@en ;
  rdfs:subClassOf obo:IAO_0000314 .

obo:ICO_0000411 a rdfs:Class ;
  rdfs:label "designated disease research purpose"@en ;
  rdfs:comment "A 'designated biomedical research purpose' that designates a process of disease specific research as its end."@en ;
  rdfs:subClassOf obo:ICO_0000345 .

obo:OBI_0002507 a rdfs:Class ;
  rdfs:label "saliva specimen" ;
  rdfs:comment "A specimen that is derived from saliva."@en ;
  rdfs:subClassOf obo:OBI_2000009 .

obo:OBI_0000338 a rdfs:Class ;
  rdfs:label "drawing a conclusion based on data"@en ;
  rdfs:comment "A planned process in which data gathered in an investigation is evaluated in the context of existing knowledge with the objective to generate more general conclusions or to conclude that the data does not allow one to draw general conclusion"@en ;
  rdfs:subClassOf obo:OBI_0000011 .

obo:OMRSE_00000027 a rdfs:Class ;
  rdfs:label "organization health care role"@en ;
  rdfs:comment "An organization social role that, if realized, is realized by either a health care process or an ancillary health care process"@en ;
  rdfs:subClassOf obo:OMRSE_00000025 .

obo:IAO_0000647 a rdfs:Class ;
  rdfs:label "Postal delivery route"@en ;
  rdfs:comment "A plan specification that if realized, is realized by the delivery of mail to some facility or mailbox within some geographical region."@en ;
  rdfs:subClassOf obo:IAO_0000104 .

<http://www.ontologyrepository.com/CommonCoreOntologies/StasisOfGenericallyDependentContinuant> a rdfs:Class ;
  rdfs:label "stasis of generically dependent continuant"@en ;
  rdfs:comment "A stasis in which some independent continuant bears some generically dependent continuant that remains unchanged during a temporal interval."@en ;
  rdfs:subClassOf <http://www.ontologyrepository.com/CommonCoreOntologies/Stasis> .

obo:ICO_0000178 a rdfs:Class ;
  rdfs:label "consenting to not to be informed about incidental finding"@en ;
  rdfs:comment "A planned process for a subject agrees not to be informed about any incidental finding."@en ;
  rdfs:subClassOf obo:OBI_0000011 .

obo:OBI_0002518 a rdfs:Class ;
  rdfs:label "prostate gland specimen" ;
  rdfs:comment "A specimen that is derived from prostate gland."@en ;
  rdfs:subClassOf obo:OBI_0001479 .

obo:ICO_0000201 a rdfs:Class ;
  rdfs:label "capability to consent"@en ;
  rdfs:comment "A cognitive capability inhering in some agent, which may be realized in an Act of Consent."@en ;
  rdfs:subClassOf obo:BFO_0000016 .

obo:RO_0000052 a rdf:Property ;
  rdfs:label "inheres in"@en ;
  rdfs:comment "a relation between a specifically dependent continuant (the characteristic) and any other entity (the bearer), in which the characteristic depends on the bearer for its existence."@en ;
  rdfs:range <https://w3id.org/linkml/Any> .

obo:IAO_0000414 a rdfs:Class ;
  rdfs:label "mass measurement datum"@en ;
  rdfs:comment "A scalar measurement datum that is the result of measurement of mass quality"@en ;
  rdfs:subClassOf obo:IAO_0000032 .

obo:ICO_0000350 a rdfs:Class ;
  rdfs:label "designated evaluation purpose"@en ;
  rdfs:comment "A 'permission purpose directive'  that designates a process of evaluation as its end."@en ;
  rdfs:subClassOf obo:ICO_0000328 .

obo:OBI_0002522 a rdfs:Class ;
  rdfs:label "adrenal gland specimen" ;
  rdfs:comment "A specimen that is derived from adrenal gland."@en ;
  rdfs:subClassOf obo:OBI_0001479 .

obo:ICO_0000145 a rdfs:Class ;
  rdfs:label "postmortem donation of biological specimen"@en ;
  rdfs:comment "A planned process in which an agent's designated biological specimen is collected after the death of the agent."@en ;
  rdfs:subClassOf obo:OBI_0000011 .

obo:BFO_0000001 a rdfs:Class ;
  rdfs:label "entity"@en ;
  rdfs:comment "from BFO"@en .

obo:IAO_0000584 a rdfs:Class ;
  rdfs:label "time sampled measurement data set"@en ;
  rdfs:comment "A data set that is an aggregate of data recording some measurement at a number of time points. The time series data set is an ordered list of pairs of time measurement data and the corresponding measurement data acquired at that time."@en ;
  rdfs:subClassOf obo:IAO_0000100 .

obo:OBI_0600038 a rdfs:Class ;
  rdfs:label "addition of molecular label"@en ;
  rdfs:comment "a material processing technique intended to add a molecular label to some input material entity, to allow detection of the molecular target of this label in a detection of molecular label assay"@en ;
  rdfs:subClassOf obo:OBI_0000094 .

obo:OMRSE_00000192 a rdfs:Class ;
  rdfs:label "obsolete communication"@en ;
  rdfs:comment "A process in which some participant shares some information content entity about some state of that participant with some other participant."@en ;
  rdfs:subClassOf obo:BFO_0000015 .

obo:ICO_0000296 a rdfs:Class ;
  rdfs:label "description of consequences of voluntarily withdrawal"@en ;
  rdfs:comment "A descriptive information content entity that describes the negative impact or harm that may befall an agent who withdraws from an investigation."@en ;
  rdfs:subClassOf <http://www.ontologyrepository.com/CommonCoreOntologies/DescriptiveInformationContentEntity> .

obo:UBERON_0001134 a rdfs:Class ;
  rdfs:label "skeletal muscle tissue" ;
  rdfs:comment "Muscle tissue that consists primarily of skeletal muscle fibers." ;
  rdfs:subClassOf obo:UBERON_0000479 .

obo:ICO_0000150 a rdfs:Class ;
  rdfs:label "eligibility screening process"@en ;
  rdfs:comment "A planned process to screen the eligibility of a candidate for a study or procedure, verifying whether certain sufficient or necessary conditions for eligibility obtain."@en ;
  rdfs:subClassOf obo:OBI_0000011 .

obo:IAO_0000640 a rdfs:Class ;
  rdfs:label "related work textual entity"@en ;
  rdfs:comment "A textual entity that discusses work from other publications and expresses their relevancy to the content of a document."@en ;
  rdfs:subClassOf obo:IAO_0000300 .

obo:IAO_0000592 a rdfs:Class ;
  rdfs:label "software module"@en ;
  rdfs:comment "A software module is software composed of a collection of software methods."@en ;
  rdfs:subClassOf obo:IAO_0000010 .

obo:IAO_0000184 a rdfs:Class ;
  rdfs:label "scatter plot"@en ;
  rdfs:comment "A scatterplot is a graph which uses Cartesian coordinates to display values for two variables for a set of data. The data is displayed as a collection of points, each having the value of one variable determining the position on the horizontal axis and the value of the other variable determining the position on the vertical axis."@en ;
  rdfs:subClassOf obo:IAO_0000038 .

obo:OBI_0002511 a rdfs:Class ;
  rdfs:label "vitreous humor specimen" ;
  rdfs:comment "A specimen that is derived from vireous humor."@en ;
  rdfs:subClassOf obo:OBI_2000004 .

obo:OGMS_0000104 a rdfs:Class ;
  rdfs:label "diagnostic process" ;
  rdfs:comment "A health care process that involves the interpretation of a clinical picture from a given patient (input) and the assertion to the effect that the patient has a disease, disorder, or syndrome of a certain type, or none of these (output)."@en ;
  rdfs:subClassOf obo:OGMS_0000096 .

obo:ICO_0000137 a rdfs:Class ;
  rdfs:label "obsolete assessment of participant candidate understanding" ;
  rdfs:comment "In order for the consent valid, the candidate should be competent to understand what has been explained."@en ;
  rdfs:subClassOf <http://www.geneontology.org/formats/oboInOwl#ObsoleteClass> .

obo:OBI_2000007 a rdfs:Class ;
  rdfs:label "nasopharynx specimen" ;
  rdfs:comment "A specimen that is derived from some nasopharynx"@en ;
  rdfs:subClassOf obo:OBI_2000006 .

obo:DUO_0000007 a rdfs:Class ;
  rdfs:label "disease specific research"@en ;
  rdfs:comment "This data use permission indicates that use is allowed provided it is related to the specified disease."@en ;
  rdfs:subClassOf obo:DUO_0000006 .

obo:IAO_8000011 a rdfs:Class ;
  rdfs:label "external import ontology module"@en ;
  rdfs:comment "An imported ontology module that is derived from an external ontology. Derivation methods include the OWLAPI SLME approach."@en ;
  rdfs:subClassOf obo:IAO_8000005 .

obo:IAO_0000324 a rdfs:Class ;
  rdfs:label "acknowledgements section"@en ;
  rdfs:comment "Part of a publication that is about the contributions of people or institutions other than the authors."@en ;
  rdfs:subClassOf obo:IAO_0000314 .

obo:OBI_2000015 a rdfs:Class ;
  rdfs:label "capillary blood specimen" ;
  rdfs:comment "A specimen that is derived from some capillary blood"@en ;
  rdfs:subClassOf obo:OBI_0000655 .

obo:ICO_0000284 a rdfs:Class ;
  rdfs:label "description of reputational risk"@en ;
  rdfs:comment "A description of risk that describes the magnitude or probability of damage to the reputation of an agent in a social context."@en ;
  rdfs:subClassOf <http://www.ontologyrepository.com/CommonCoreOntologies/DescriptiveInformationContentEntity> .

obo:PATO_0000051 a rdfs:Class ;
  rdfs:label "morphology" ;
  rdfs:comment "A quality of a single physical entity inhering in the bearer by virtue of the bearer's size or shape or structure." ;
  rdfs:subClassOf obo:PATO_0001241 .

obo:IAO_0000088 a rdfs:Class ;
  rdfs:label "report"@en ;
  rdfs:comment "A document assembled by an author for the purpose of providing information for the audience. A report is the output of a documenting process and has the objective to be consumed by a specific audience. Topic of the report is on something that has completed. A report is not a single figure. Examples of reports are journal article, patent application, grant progress report, case report (not patient record)."@en ;
  rdfs:subClassOf obo:IAO_0000310 .

obo:ICO_0000053 a rdfs:Class ;
  rdfs:label "drug testing investigation"@en ;
  rdfs:comment "An investigation that targets drug testing."@en ;
  rdfs:subClassOf obo:OBI_0000066 .

obo:ICO_0000389 a rdfs:Class ;
  rdfs:label "designated government organization"@en ;
  rdfs:comment "A 'designated organization' that designates a government organization."@en ;
  rdfs:subClassOf obo:ICO_0000384 .

obo:BFO_0000146 a rdfs:Class ;
  rdfs:label "two-dimensional continuant fiat boundary"@en ;
  rdfs:subClassOf obo:BFO_0000140 .

obo:BFO_0000015 a rdfs:Class ;
  rdfs:label "process"@en ;
  rdfs:comment "p is a process = Def. p is an occurrent that has temporal proper parts and for some time t, p s-depends_on some material entity at t. (axiom label in BFO2 Reference: [083-003])"@en ;
  rdfs:subClassOf obo:BFO_0000003 .

obo:UBERON_0001264 a rdfs:Class ;
  rdfs:label "pancreas" ;
  rdfs:comment "An endoderm derived structure that produces precursors of digestive enzymes and blood glucose regulating hormones[GO]." ;
  rdfs:subClassOf obo:UBERON_0000465 .

obo:ICO_0000331 a rdfs:Class ;
  rdfs:label "designated procedure"@en ;
  rdfs:comment "A 'designated action' that designates a procedure as permissable."@en ;
  rdfs:subClassOf obo:ICO_0000324 .

obo:ICO_0000003 a rdfs:Class ;
  rdfs:label "validating an informed consent form"@en ;
  rdfs:comment "A planned process that validates an informed consent form."@en ;
  rdfs:subClassOf obo:OBI_0000011 .

obo:UBERON_0001013 a rdfs:Class ;
  rdfs:label "adipose tissue" ;
  rdfs:comment "Portion of connective tissue composed of adipocytes enmeshed in areolar tissue." ;
  rdfs:subClassOf obo:UBERON_0000479 .

obo:ICO_0000118 a rdfs:Class ;
  rdfs:label "repository of documents"@en ;
  rdfs:comment "A site where documents are preserved."@en ;
  rdfs:subClassOf obo:BFO_0000029 .

obo:ICO_0000324 a rdfs:Class ;
  rdfs:label "designated action"@en ;
  rdfs:comment "A 'Directive Information Content Entity' that designates a process as permissable."@en ;
  rdfs:subClassOf <http://www.ontologyrepository.com/CommonCoreOntologies/DesignativeInformationContentEntity> .

obo:IAO_0000007 a rdfs:Class ;
  rdfs:label "action specification"@en ;
  rdfs:comment "A directive information entity that describes an action the bearer will take."@en ;
  rdfs:subClassOf obo:IAO_0000033 .

obo:DUO_0000018 a rdfs:Class ;
  rdfs:label "not for profit, non commercial use only"@en ;
  rdfs:comment "This data use modifier indicates that use of the data is limited to not-for-profit organizations and not-for-profit use, non-commercial use."@en ;
  rdfs:subClassOf obo:DUO_0000017 .

obo:IAO_0000031 a rdfs:Class ;
  rdfs:label "integer numeral"@en ;
  rdfs:comment "A numeral that denotes an integer"@en ;
  rdfs:subClassOf obo:IAO_0000029 .

obo:ICO_0000044 a rdfs:Class ;
  rdfs:label "informed consent identification code"@en ;
  rdfs:comment "A data item consisting of a unique identification code designating an informed consent."@en ;
  rdfs:subClassOf obo:IAO_0000027 .

obo:IAO_0021030 a rdfs:Class ;
  rdfs:label "obsoleted_document act target"@en ;
  rdfs:comment "The human being or organization or aggregate of any of the aforementioned that is the bearer of a concretization of a socio-legal generically dependent continuant brought about by or transferred in a specific document act." ;
  rdfs:subClassOf <http://www.geneontology.org/formats/oboInOwl#ObsoleteClass> .

obo:OBI_0001479 a rdfs:Class ;
  rdfs:label "specimen from organism" ;
  rdfs:comment "A specimen that derives from an anatomical part or substance arising from an organism. Examples of tissue specimen include tissue, organ, physiological system, blood, or body location (arm)."@en ;
  rdfs:subClassOf obo:OBI_0100051 .

obo:BFO_0000004 a rdfs:Class ;
  rdfs:label "independent continuant"@en ;
  rdfs:comment "b is an independent continuant = Def. b is a continuant which is such that there is no c and no t such that b s-depends_on c at t. (axiom label in BFO2 Reference: [017-002])"@en ;
  rdfs:subClassOf obo:BFO_0000002 .

obo:ICO_0000115 a rdfs:Class ;
  rdfs:label "obsolete anonymized genomic sample" ;
  rdfs:comment "An anonymized information content entity about a genomic sample."@en ;
  rdfs:subClassOf <http://www.geneontology.org/formats/oboInOwl#ObsoleteClass> .

obo:IAO_0000573 a rdfs:Class ;
  rdfs:label "line graph"@en ;
  rdfs:comment """A line graph is a type of graph created by connecting a series of data
points together with a line."""@en ;
  rdfs:subClassOf obo:IAO_0000038 .

obo:OBI_0001909 a rdfs:Class ;
  rdfs:label "conclusion based on data" ;
  rdfs:comment "An information content entity that is inferred from data."@en ;
  rdfs:subClassOf obo:IAO_0000030 .

obo:OBI_0000124 a rdf:Property ;
  rdfs:label "is_supported_by_data" ;
  rdfs:comment "The relation between a data item and a conclusion where the conclusion is the output of a data interpreting process and the data item is used as an input to that process"@en ;
  rdfs:domain obo:OBI_0001909 ;
  rdfs:range obo:IAO_0000027 .

obo:ICO_0000313 a rdfs:Class ;
  rdfs:label "excess material role"@en ;
  rdfs:comment "A role inhering in some material entity that is realized in an act of artifact modification where the material entity is separated from another portion of material."@en ;
  rdfs:subClassOf obo:BFO_0000023 .

obo:UBERON_0000473 a rdfs:Class ;
  rdfs:label "testis" ;
  rdfs:comment "A gonad of a male animal. A gonad produces and releases sperm." ;
  rdfs:subClassOf obo:UBERON_0000465 .

obo:NCBITaxon_33154 a rdfs:Class ;
  rdfs:label "Opisthokonta" ;
  rdfs:subClassOf obo:NCBITaxon_2759 .

obo:ICO_0000058 a rdfs:Class ;
  rdfs:label "investigation period"@en ;
  rdfs:comment "A one-dimensional temporal region to which an investigation stands in the occupies_temporal_region relation."@en ;
  rdfs:subClassOf obo:BFO_0000038 .

obo:ICO_0000143 a rdfs:Class ;
  rdfs:label "obsolete assent process" ;
  rdfs:comment "A planned process of acknowledgement, or agreement, to participate in a procedure or study, where the participant is incapable of informed consent."@en ;
  rdfs:subClassOf <http://www.geneontology.org/formats/oboInOwl#ObsoleteClass> .

obo:ICO_0000020 a rdfs:Class ;
  rdfs:label "human subject signature section in informed consent form"@en ;
  rdfs:comment "A signature section in informed consent element that that is specified as a place to receive a signature from a human subject."@en ;
  rdfs:subClassOf obo:ICO_0000019 .

obo:ICO_0000039 a rdfs:Class ;
  rdfs:label "project end date specification"@en ;
  rdfs:comment "A date specification that designates the date when a project ends."@en ;
  rdfs:subClassOf obo:ICO_0000022 .

obo:ICO_0000205 a rdfs:Class ;
  rdfs:label "consenter"@en ;
  rdfs:comment "An agent who, at some time, was the bearer of a consent power role, which was, in fact, realized in an act of informed consenting, and who, as a result of this act of informed consenting, now bears a consenter role."@en ;
  rdfs:subClassOf obo:NCBITaxon_9606 .

obo:OBI_0002605 a rdfs:Class ;
  rdfs:label "cheek swab specimen" ;
  rdfs:comment "A specimen that is collected with a swab from the cheek portion of the inside surface of a mouth."@en ;
  rdfs:subClassOf obo:OBI_0002607 .

obo:OBI_0002540 a rdfs:Class ;
  rdfs:label "coronary artery specimen" ;
  rdfs:comment "A specimen that is derived from coronary artery."@en ;
  rdfs:subClassOf obo:OBI_0001479 .

obo:UBERON_0000945 a rdfs:Class ;
  rdfs:label "stomach" ;
  rdfs:comment "An expanded region of the vertebrate alimentary tract that serves as a food storage compartment and digestive organ. A stomach is lined, in whole or in part by a glandular epithelium." ;
  rdfs:subClassOf obo:UBERON_0000465 .

obo:OBI_0002527 a rdfs:Class ;
  rdfs:label "pancreas specimen" ;
  rdfs:comment "A specimen that is derived from pancreas."@en ;
  rdfs:subClassOf obo:OBI_0001479 .

obo:ICO_0000161 a rdfs:Class ;
  rdfs:label "biological sample collecting"@en ;
  rdfs:comment "A planned process in which a biological sample from a subject is collected for testing."@en ;
  rdfs:subClassOf obo:OBI_0000011 .

obo:BFO_0000009 a rdfs:Class ;
  rdfs:label "two-dimensional spatial region"@en ;
  rdfs:subClassOf obo:BFO_0000006 .

obo:ICO_0000029 a rdfs:Class ;
  rdfs:label "informed consent form for clinical study"@en ;
  rdfs:comment "An informed consent form that is used for a clinical study."@en .

obo:UBERON_0013757 a rdfs:Class ;
  rdfs:label "capillary blood" ;
  rdfs:comment "A blood that is part of a capillary." ;
  rdfs:subClassOf obo:UBERON_0000178 .

obo:OBI_2000003 a rdfs:Class ;
  rdfs:label "throat specimen" ;
  rdfs:comment "A specimen that is derived from some throat"@en ;
  rdfs:subClassOf obo:OBI_0001479 .

obo:OBI_0003652 a rdfs:Class ;
  rdfs:label "albumin-free serum" ;
  rdfs:comment "A blood serum specimen that contains no albumin."@en ;
  rdfs:subClassOf obo:OBI_0100017 .

obo:ICO_0000055 a rdfs:Class ;
  rdfs:label "obsolete genetic study" ;
  rdfs:comment "An investigation that has process part some genetic analysis."@en ;
  rdfs:subClassOf <http://www.geneontology.org/formats/oboInOwl#ObsoleteClass> .

obo:OMRSE_00000023 a rdfs:Class ;
  rdfs:label "collection of humans"@en ;
  rdfs:comment "An object aggregate all of whose components are human beings."@en ;
  rdfs:subClassOf obo:OMRSE_00000022 .

obo:OMRSE_00000020 a rdf:Property ;
  rdfs:label "is-aggregate-of" ;
  rdfs:comment """We anticipate BFO 2.0 including and defining this relation.  When it does, we will obsolete this property and declare it equivalent to the BFO 2.0 relation.
"""@en ;
  rdfs:range <https://w3id.org/linkml/Any> .

obo:ICO_0000080 a rdfs:Class ;
  rdfs:label "research assistant role" ;
  rdfs:comment "a role inhering in a homo sapiens that, if realized, is realized in assisting with a research process."@en ;
  rdfs:subClassOf obo:BFO_0000023 .

obo:IAO_0000029 a rdfs:Class ;
  rdfs:label "numeral"@en ;
  rdfs:comment "A symbol that denotes a number."@en ;
  rdfs:subClassOf obo:IAO_0000028 .

obo:ICO_0000186 a rdfs:Class ;
  rdfs:label "permission temporal region"@en ;
  rdfs:comment "A temporal region during which some act is permitted."@en ;
  rdfs:subClassOf obo:BFO_0000008 .

obo:IAO_0021004 a rdfs:Class ;
  rdfs:label "obsolete_socio-legal generically dependent continuant"@en ;
  rdfs:comment "Socio-legal generically dependent continuants are generically dependent continuants that come into existence through social acts and that if they get concretized are concretized as realizable entities."@en ;
  rdfs:subClassOf <http://www.geneontology.org/formats/oboInOwl#ObsoleteClass> .

obo:OBI_0002599 a rdfs:Class ;
  rdfs:label "swab specimen" ;
  rdfs:comment "A specimen that is stored on a swab as the output of a collecting specimen with swab process."@en ;
  rdfs:subClassOf obo:OBI_0100051 .

obo:OBI_0000848 a rdfs:Class ;
  rdfs:label "polyA RNA extraction" ;
  rdfs:comment "A RNA extraction process typically involving the use of poly dT oligomers in which the desired output material is polyA RNA."@en ;
  rdfs:subClassOf obo:OBI_0666666 .

obo:IAO_0020024 a rdfs:Class ;
  rdfs:label "credential role"@en ;
  rdfs:comment "A role that inheres in a concretization of an identity document and is realized by an authentication process."@en ;
  rdfs:subClassOf obo:BFO_0000023 .

obo:ICO_0000129 a rdfs:Class ;
  rdfs:label "informed consent form for human saliva sample collection"@en ;
  rdfs:comment "An informed consent form for human sample collection that is specifically for human saliva sample collection."@en .

obo:ICO_0000042 a rdfs:Class ;
  rdfs:label "obligation informed consent rule specification"@en ;
  rdfs:comment "An informed consent rule specification that specifies a course of action legally required to be taken."@en ;
  rdfs:subClassOf obo:ICO_0000041 .

obo:ICO_0000181 a rdfs:Class ;
  rdfs:label "secondary use"@en ;
  rdfs:comment "A planned process that involves a human biological specimen originally collected for the purpose of treatment or a different investigation."@en ;
  rdfs:subClassOf obo:OBI_0000011 .

obo:UBERON_0001621 a rdfs:Class ;
  rdfs:label "coronary artery" ;
  rdfs:comment "An artery that supplies the myocardium." ;
  rdfs:subClassOf obo:UBERON_0001637 .

obo:ICO_0000194 a rdfs:Class ;
  rdfs:label "obsolete social act (placeholder)" ;
  rdfs:comment "A process that is carried out by a conscious being or an aggregate of conscious beings, and is spontaneous, directed towards another conscious being or another aggregate of conscious beings, and that needs to be perceived."@en ;
  rdfs:subClassOf <http://www.geneontology.org/formats/oboInOwl#ObsoleteClass> .

obo:UBERON_0012168 a rdfs:Class ;
  rdfs:label "umbilical cord blood" ;
  rdfs:comment "Blood that remains in the placenta and in the attached umbilical cord after childbirth[WP]." ;
  rdfs:subClassOf obo:UBERON_0013755 .

obo:OBI_0000921 a rdfs:Class ;
  rdfs:label "labeled RNA extract" ;
  rdfs:comment "a labeled specimen that is the output of a labeling process and has grain labeled RNA to be able to detect RNA in future experiments."@en ;
  rdfs:subClassOf obo:OBI_0001143 .

obo:DUO_0000040 a rdfs:Class ;
  rdfs:label "disease category research" ;
  rdfs:comment "Biomedical research research concerning specific disease/s" ;
  rdfs:subClassOf obo:DUO_0000037 .

obo:IAO_0000018 a rdfs:Class ;
  rdfs:label "obsolete_material_entity" ;
  rdfs:subClassOf <http://www.geneontology.org/formats/oboInOwl#ObsoleteClass> .

<http://www.ontologyrepository.com/CommonCoreOntologies/Stasis> a rdfs:Class ;
  rdfs:label "stasis"@en ;
  rdfs:comment "A process in which some independent continuant endures and one or more of the dependent entities it bears does not change in kind or intensity."@en ;
  rdfs:subClassOf obo:BFO_0000015 .

obo:ICO_0000306 a rdfs:Class ;
  rdfs:label "act of waiving"@en ;
  rdfs:comment "A social act of relinquishing a right, claim, or privilege."@en ;
  rdfs:subClassOf obo:IAO_0021003 .

obo:BFO_0000028 a rdfs:Class ;
  rdfs:label "three-dimensional spatial region"@en ;
  rdfs:subClassOf obo:BFO_0000006 .

obo:UBERON_0001557 a rdfs:Class ;
  rdfs:label "upper respiratory tract" ;
  rdfs:comment "The segment of the respiratory tract that starts proximally with the nose and ends distally with the cricoid cartilage, before continuing to the trachea." ;
  rdfs:subClassOf obo:UBERON_0000465 .

obo:CHEBI_23367 a rdfs:Class ;
  rdfs:label "molecular entity" ;
  rdfs:comment "Any constitutionally or isotopically distinct atom, molecule, ion, ion pair, radical, radical ion, complex, conformer etc., identifiable as a separately distinguishable entity." ;
  rdfs:subClassOf obo:BFO_0000040 .

obo:OBI_0000915 a rdfs:Class ;
  rdfs:label "freezing storage" ;
  rdfs:comment "A storage process in temperature that maintenance the frozen status of the stored entities."@en ;
  rdfs:subClassOf obo:OBI_0302893 .

obo:ICO_0000400 a rdfs:Class ;
  rdfs:label "designated consenting actor"@en ;
  rdfs:comment "A 'designated actor' that designates the actor that is permitting some 'designated action'."@en ;
  rdfs:subClassOf obo:ICO_0000325 .

obo:OBI_2000012 a rdfs:Class ;
  rdfs:label "umbilical cord blood specimen" ;
  rdfs:comment "A specimen that is derived from some umbilical cord blood"@en ;
  rdfs:subClassOf obo:OBI_0000655 , obo:OBI_2000013 .

obo:IAO_0000312 a rdfs:Class ;
  rdfs:label "publication about an investigation"@en ;
  rdfs:comment "A publication that is about an investigation"@en ;
  rdfs:subClassOf obo:IAO_0000311 .

obo:OBI_0000079 a rdfs:Class ;
  rdfs:label "culture medium"@en ;
  rdfs:comment "a processed material that provides the needed nourishment for microorganisms or cells grown in vitro."@en ;
  rdfs:subClassOf obo:OBI_0000047 .

obo:ICO_0000262 a rdfs:Class ;
  rdfs:label "cognitive impairment"@en ;
  rdfs:comment "A disposition to abnormality realized in cognitive processes that are qualitatively below those of individuals belonging to some type, to which the bearer of the disposition also belongs."@en ;
  rdfs:subClassOf obo:BFO_0000016 .

obo:OBI_0002127 a rdfs:Class ;
  rdfs:label "single cell specimen" ;
  rdfs:comment "A cell specimen that contains only one cell."@en ;
  rdfs:subClassOf obo:OBI_0001468 .

obo:DUO_0000003 a rdfs:Class ;
  rdfs:label "obsolete consent code secondary category" ;
  rdfs:comment "A categorical data item indicating the secondary category the consent code belongs to according to Dyke et al. 2016." ;
  rdfs:subClassOf <http://www.geneontology.org/formats/oboInOwl#ObsoleteClass> .

obo:OBI_0002691 a rdfs:Class ;
  rdfs:label "arthropod meal of blood specimen" ;
  rdfs:comment "A specimen of the blood ingested by an arthropod."@en ;
  rdfs:subClassOf obo:OBI_0000655 .

obo:OBI_0000378 a rdfs:Class ;
  rdfs:label "filter function"@en ;
  rdfs:comment "A filter function is a function to prevent the flow of certain entities based on a quality or qualities of the entity while allowing entities which have different qualities to pass through"@en ;
  rdfs:subClassOf obo:OBI_0000372 .

obo:OBI_0003055 a rdfs:Class ;
  rdfs:label "blood specimen on filter paper" ;
  rdfs:comment "A blood specimen that is located on a filter paper."@en ;
  rdfs:subClassOf obo:OBI_0000655 .

obo:BFO_0000142 a rdfs:Class ;
  rdfs:label "one-dimensional continuant fiat boundary"@en ;
  rdfs:subClassOf obo:BFO_0000140 .

obo:ICO_0000167 a rdfs:Class ;
  rdfs:label "obsolete permittee deontic role in genetic research" ;
  rdfs:comment "A deontic role that if realized is realized by its bearer conducting or overseeing genetic research on the genome of a human donor."@en ;
  rdfs:subClassOf <http://www.geneontology.org/formats/oboInOwl#ObsoleteClass> .

obo:DUO_0000022 a rdfs:Class ;
  rdfs:label "geographical restriction"@en ;
  rdfs:comment "This data use modifier indicates that use is limited to within a specific geographic region."@en ;
  rdfs:subClassOf obo:DUO_0000017 .

obo:IAO_0000059 a rdfs:Class ;
  rdfs:label "obsolete2_report figure"@en ;
  rdfs:comment "A report figure is a report display element that has some aspect of illustration, but may be a composite of figures, images, and other elements"@en ;
  rdfs:subClassOf <http://www.geneontology.org/formats/oboInOwl#ObsoleteClass> .

obo:APOLLO_SV_00000524 a rdfs:Class ;
  rdfs:label "compiling software"@en ;
  rdfs:comment "A planned process that converts human-written or curated software into a machine-executable or interpretable set of instructions."@en ;
  rdfs:subClassOf obo:APOLLO_SV_00000008 .

obo:DUO_0000014 a rdfs:Class ;
  rdfs:label "obsolete research use only"@en ;
  rdfs:comment "This data use limitation indicates that use is limited to research purposes (e.g., does not include its use in clinical care)."@en ;
  rdfs:subClassOf <http://www.geneontology.org/formats/oboInOwl#ObsoleteClass> .

obo:OBIB_0000702 a rdfs:Class ;
  rdfs:label "medical record"@en ;
  rdfs:comment "A document that contains information representing health-relevant qualities of a patient written in a chronological manner and that is primarily used for patient care in a clinical setting."@en ;
  rdfs:subClassOf obo:IAO_0000310 .

obo:ICO_0000097 a rdfs:Class ;
  rdfs:label "obsolete mental health care record" ;
  rdfs:comment "A medical record that describes a patient's mental health care history."@en ;
  rdfs:subClassOf <http://www.geneontology.org/formats/oboInOwl#ObsoleteClass> .

obo:UBERON_0001830 a rdfs:Class ;
  rdfs:label "minor salivary gland" ;
  rdfs:comment "One of the smaller, largely mucus-secreting, exocrine glands of the oral cavity, consisting of the labial, buccal, molar, lingual, and palatine glands[MP]." ;
  rdfs:subClassOf obo:UBERON_0000465 .

obo:OBI_0500028 a rdfs:Class ;
  rdfs:label "exclusion criterion"@en ;
  rdfs:comment "an exclusion criterion (rule) is_a *eligibility criterion*  which defines and states a condition which, if met, makes an entity unsuitable for a given task or participation in a given process. For instance, in a study protocol, exclusion criteria indicate the conditions that prospective subjects SHOULD NOT meet to be eligible for participation in a study"@en ;
  rdfs:subClassOf obo:OBI_0500026 .

obo:IAO_0000104 a rdfs:Class ;
  rdfs:label "plan specification"@en ;
  rdfs:comment "A directive information entity with action specifications and objective specifications as parts that, when concretized, is realized in a process in which the bearer tries to achieve the objectives by taking the actions specified."@en ;
  rdfs:subClassOf obo:IAO_0000033 .

obo:UBERON_0013755 a rdfs:Class ;
  rdfs:label "arterial blood" ;
  rdfs:comment "A blood that is part of a artery." ;
  rdfs:subClassOf obo:UBERON_0000178 .

obo:OBI_0000680 a rdfs:Class ;
  rdfs:label "whole organism preparation" ;
  rdfs:comment "A material entity which is the output of a process in which one or more whole organisms are prepared in a way to make it easier to study them, and in which the great majority of organismal parts are maintained"@en ;
  rdfs:subClassOf obo:OBI_0100051 .

obo:UBERON_0001089 a rdfs:Class ;
  rdfs:label "sweat" ;
  rdfs:comment "Secretion produced by a sweat gland." ;
  rdfs:subClassOf obo:UBERON_0006314 .

obo:OBI_0600024 a rdfs:Class ;
  rdfs:label "maintaining cell culture"@en ;
  rdfs:comment "A planned process with the objective to keep cells alive in a defined environment outside of an organism."@en ;
  rdfs:subClassOf obo:OBI_0000838 .

obo:IAO_0021015 a rdfs:Class ;
  rdfs:label "obsolete_document template creator role"@en ;
  rdfs:comment "The role of a human being or an aggregate of human beings preparing the initial document to undergo a document act, thus creating a socio-legal generically dependent continuant."@en ;
  rdfs:subClassOf <http://www.geneontology.org/formats/oboInOwl#ObsoleteClass> .

obo:ICO_0000372 a rdfs:Class ;
  rdfs:label "designated image data"@en ;
  rdfs:comment "A 'designated data' that designates image data."@en ;
  rdfs:subClassOf obo:ICO_0000367 .

obo:ICO_0000273 a rdfs:Class ;
  rdfs:label "research method directive"@en ;
  rdfs:comment "A directive information entity that prescribes some research process."@en ;
  rdfs:subClassOf obo:IAO_0000033 .

obo:ICO_0000317 a rdfs:Class ;
  rdfs:label "patient role directive"@en ;
  rdfs:comment "A role directive that prescribes the bearer of a patient role in a process."@en ;
  rdfs:subClassOf obo:ICO_0000316 .

obo:OBI_0002529 a rdfs:Class ;
  rdfs:label "pituitary gland specimen" ;
  rdfs:comment "A specimen that is derived from pituitary gland."@en ;
  rdfs:subClassOf obo:OBI_0001479 .

obo:OBI_0001622 a rdfs:Class ;
  rdfs:label "investigation title"@en ;
  rdfs:comment "A textual entity that denotes an investigation."@en ;
  rdfs:subClassOf obo:OBI_0001898 .

obo:UBERON_0000956 a rdfs:Class ;
  rdfs:label "cerebral cortex" ;
  rdfs:comment "The thin layer of gray matter on the surface of the cerebral hemisphere that develops from the telencephalon. It consists of the neocortex (6 layered cortex or isocortex), the hippocampal formation and the olfactory cortex." ;
  rdfs:subClassOf obo:UBERON_0000465 .

obo:OBI_0002500 a rdfs:Class ;
  rdfs:label "amniotic fluid specimen" ;
  rdfs:comment "A specimen that is derived from amniotic fluid."@en ;
  rdfs:subClassOf obo:OBI_2000009 .

obo:UBERON_0002116 a rdfs:Class ;
  rdfs:label "ileum" ;
  rdfs:comment "The portion of the small intestine that extends from the jejunum to the colon." ;
  rdfs:subClassOf obo:UBERON_0000465 .

obo:ICO_0000126 a rdfs:Class ;
  rdfs:label "storage duration of signed informed consent form"@en ;
  rdfs:comment "A temporal interval that represents a period of time during which a signed informed consent form is stored."@en ;
  rdfs:subClassOf obo:BFO_0000008 .

obo:ICO_0000192 a rdfs:Class ;
  rdfs:label "description of broad consent"@en ;
  rdfs:comment "A description of allowed action types that has in view a wide, unspecified range of action types, and is restricted only by a regulator body."@en ;
  rdfs:subClassOf <http://www.ontologyrepository.com/CommonCoreOntologies/DescriptiveInformationContentEntity> .

obo:ICO_0000033 a rdfs:Class ;
  rdfs:label "informed consent form for qualitative research involving children"@en ;
  rdfs:comment "An informed consent form for qualitative study that involves children."@en .

obo:ICO_0000409 a rdfs:Class ;
  rdfs:label "designated ancestry research purpose"@en ;
  rdfs:comment "A 'designated research purpose' that designates ancestry research as its end."@en ;
  rdfs:subClassOf obo:ICO_0000344 .

obo:ICO_0000156 a rdfs:Class ;
  rdfs:label "adult consent process"@en ;
  rdfs:comment "An informed consent process where the person who is being asked to consent is an adult."@en ;
  rdfs:subClassOf obo:OBI_0000810 .

obo:IAO_0000629 a rdfs:Class ;
  rdfs:label "keyword textual entity"@en ;
  rdfs:comment "A textual entity listing keywords indicating the major theme(s) of a document."@en ;
  rdfs:subClassOf obo:IAO_0000300 .

obo:UBERON_0001913 a rdfs:Class ;
  rdfs:label "milk" ;
  rdfs:comment "An emulsion of fat globules within a fluid that is secreted by the mammary gland during lactation." ;
  rdfs:subClassOf obo:UBERON_0006314 .

obo:ICO_0000107 a rdfs:Class ;
  rdfs:label "study termination"@en ;
  rdfs:comment "A process that terminates a study."@en ;
  rdfs:subClassOf obo:BFO_0000015 .

obo:ICO_0000014 a rdfs:Class ;
  rdfs:label "informed consent form for human blood sample collection"@en ;
  rdfs:comment "An informed consent form that is specifically for human blood sample collection."@en .

obo:OBI_0002432 a rdfs:Class ;
  rdfs:label "history of sex with someone with a history of blood borne infection  exclusion criterion" ;
  rdfs:comment "An exclusion criterion defined  as whether an individual has a history of sex with someone who has been diagnosed or at risk for a blood borne infections disease in a specified time frame, which if met, makes the individual unsuitable for a given task or participation in a given process."@en ;
  rdfs:subClassOf obo:OBI_0500028 .

obo:GO_0007565 a rdfs:Class ;
  rdfs:label "female pregnancy" ;
  rdfs:comment "The set of physiological processes that allow an embryo or foetus to develop within the body of a female animal. It covers the time from fertilization of a female ovum by a male spermatozoon until birth." ;
  rdfs:subClassOf obo:BFO_0000015 .

obo:OBI_0000922 a rdfs:Class ;
  rdfs:label "frozen specimen" ;
  rdfs:comment "A specimen that has been frozen in order to store it."@en ;
  rdfs:subClassOf obo:OBI_0001472 , obo:OBI_0100051 .

obo:OBI_0000011 a rdfs:Class ;
  rdfs:label "planned process"@en ;
  rdfs:comment "A process that realizes a plan which is the concretization of a plan specification."@en ;
  rdfs:subClassOf obo:BFO_0000015 .

obo:ICO_0000368 a rdfs:Class ;
  rdfs:label "designated waveform data"@en ;
  rdfs:comment "A 'designated data' that designates waveform data."@en ;
  rdfs:subClassOf obo:ICO_0000367 .

obo:BFO_0000008 a rdfs:Class ;
  rdfs:label "temporal region"@en ;
  rdfs:subClassOf obo:BFO_0000003 .

obo:OBI_0002609 a rdfs:Class ;
  rdfs:label "rectal swab specimen" ;
  rdfs:comment "A specimen that is collected with a swab from the surface of a rectum."@en ;
  rdfs:subClassOf obo:OBI_0002599 , obo:OBI_0003483 .

obo:IAO_0000033 a rdfs:Class ;
  rdfs:label "directive information entity"@en ;
  rdfs:comment "An information content entity whose concretizations indicate to their bearer how to realize them in a process."@en ;
  rdfs:subClassOf obo:IAO_0000030 .

obo:IAO_0000306 a rdfs:Class ;
  rdfs:label "table"@en ;
  rdfs:comment "A textual entity that contains a two-dimensional arrangement of texts repeated at regular intervals across a spatial range, such that the spatial relationships among the constituent texts expresses propositions"@en ;
  rdfs:subClassOf obo:IAO_0000300 .

obo:IAO_0000401 a rdfs:Class ;
  rdfs:label "one dimensional cartesian spatial coordinate datum"@en ;
  rdfs:comment "A cartesion spatial coordinate datum that  uses one value to specify a position along a one dimensional spatial region"@en ;
  rdfs:subClassOf obo:IAO_0000400 .

obo:OBI_0000953 a rdfs:Class ;
  rdfs:label "processed specimen" ;
  rdfs:comment "A specimen that has been intentionally physically modified."@en ;
  rdfs:subClassOf obo:OBI_0000047 , obo:OBI_0100051 .

obo:ICO_0000185 a rdfs:Class ;
  rdfs:label "informed assent form for cognitively impaired"@en ;
  rdfs:comment "An informed consent form that is adapted to the cognitive capacities of someone with significant mental impairment."@en ;
  rdfs:subClassOf obo:ICO_0000085 .

obo:OBI_0002611 a rdfs:Class ;
  rdfs:label "vagina swab specimen" ;
  rdfs:comment "A specimen that is collected with a swab from the surface of a vagina."@en ;
  rdfs:subClassOf obo:OBI_0002554 , obo:OBI_0002599 .

obo:ICO_0000028 a rdfs:Class ;
  rdfs:label "obsolete human blood sample collection section" ;
  rdfs:comment "A document part that describes and specifies human blood sample collection procedures."@en ;
  rdfs:subClassOf <http://www.geneontology.org/formats/oboInOwl#ObsoleteClass> .

obo:OBI_0003483 a rdfs:Class ;
  rdfs:label "digestive tract specimen" ;
  rdfs:comment "A specimen that is derived from part of a digestive tract."@en ;
  rdfs:subClassOf obo:OBI_0001479 .

obo:OBI_0002510 a rdfs:Class ;
  rdfs:label "synovial fluid specimen" ;
  rdfs:comment "A specimen that is derived from synovial fluid."@en ;
  rdfs:subClassOf obo:OBI_2000009 .

obo:ICO_0000398 a rdfs:Class ;
  rdfs:label "designated permitting actor"@en ;
  rdfs:comment "A 'designated actor' that designates an actor that may permit some 'designated action'."@en ;
  rdfs:subClassOf obo:ICO_0000325 .

obo:OBI_0002535 a rdfs:Class ;
  rdfs:label "esophagus muscularis mucosa specimen" ;
  rdfs:comment "A specimen that is derived from esophagus muscularis mucosa."@en ;
  rdfs:subClassOf obo:OBI_0003483 .

obo:OBI_0002431 a rdfs:Class ;
  rdfs:label "intravenous drug use exclusion criterion" ;
  rdfs:comment "An exclusion criterion defined as when an individual has a history of intravenous drug abuse for a specific timeframe, which if met, makes the individual unsuitable for a given task or participation in a given process."@en ;
  rdfs:subClassOf obo:OBI_0500028 .

obo:BFO_0000002 a rdfs:Class ;
  rdfs:label "continuant"@en ;
  rdfs:comment "An entity that exists in full at any time in which it exists at all, persists through time while maintaining its identity and has no temporal parts."@en ;
  rdfs:subClassOf obo:BFO_0000001 .

obo:OBI_0002662 a rdfs:Class ;
  rdfs:label "bone marrow biopsy" ;
  rdfs:comment "A biopsy where a small amount of bone and a small amount of fluid and bone marrow are collected."@en ;
  rdfs:subClassOf obo:OBI_0002650 .

obo:ICO_0000100 a rdfs:Class ;
  rdfs:label "research-related injury"@en ;
  rdfs:comment "A physical injury or illness that is a direct result of the treatment, or procedures required by the protocol, to which the subject would not have been exposed had they not participated in the study."@en ;
  rdfs:subClassOf obo:OGMS_0000102 .

obo:ICO_0000206 a rdfs:Class ;
  rdfs:label "obsolete consenter role" ;
  rdfs:comment "A deontic role that is output of some Act of Consent and, in some contexts, may be realized in revoking or modifying the permission role that was output of the same Act of Consent."@en ;
  rdfs:subClassOf <http://www.geneontology.org/formats/oboInOwl#ObsoleteClass> .

obo:ICO_0000060 a rdfs:Class ;
  rdfs:label "act of storing a specimen"@en ;
  rdfs:comment "A planned process that involves placing a specimen in some location in order to maintain possession of it."@en ;
  rdfs:subClassOf obo:ICO_0000227 .

obo:IAO_0000317 a rdfs:Class ;
  rdfs:label "methods section"@en ;
  rdfs:comment "A part of a publication about an investigation that is about the study design of the investigation"@en ;
  rdfs:subClassOf obo:IAO_0000314 .

obo:OBI_0000181 a rdfs:Class ;
  rdfs:label "population"@en ;
  rdfs:comment "a population is a collection of individuals from the same taxonomic class living, counted or sampled at a particular site or in a particular area"@en ;
  rdfs:subClassOf obo:BFO_0000040 .

obo:UBERON_0000007 a rdfs:Class ;
  rdfs:label "pituitary gland" ;
  rdfs:comment "The pituitary gland is an endocrine gland that secretes hormones that regulate many other glands [GO]. An endocrine gland located ventral to the diencephalon and derived from mixed neuroectodermal and non neuroectodermal origin [ZFIN]." ;
  rdfs:subClassOf obo:UBERON_0000465 .

obo:OBI_0002604 a rdfs:Class ;
  rdfs:label "breast swab specimen" ;
  rdfs:comment "A specimen that is collected with a swab from the surface of a breast."@en ;
  rdfs:subClassOf obo:OBI_0002523 , obo:OBI_0002599 .

obo:ICO_0000009 a rdfs:Class ;
  rdfs:label "recontact method directive"@en ;
  rdfs:comment "A document part that prescribes a method of contact in the future."@en ;
  rdfs:subClassOf obo:IAO_0000033 .

obo:IAO_0000326 a rdfs:Class ;
  rdfs:label "supplementary material to a document"@en ;
  rdfs:comment "A part of a document that is segregated from the rest of the document due to its size"@en ;
  rdfs:subClassOf obo:IAO_0000314 .

obo:ICO_0000333 a rdfs:Class ;
  rdfs:label "designated process of destruction"@en ;
  rdfs:comment "A 'designated action' that designates a process of destruction as permissable."@en ;
  rdfs:subClassOf obo:ICO_0000324 .

obo:ICO_0000158 a rdfs:Class ;
  rdfs:label "act of declining to provide consent"@en ;
  rdfs:comment "A planned process in which a person decides not to provide consent."@en ;
  rdfs:subClassOf obo:OBI_0000011 .

obo:ICO_0000062 a rdfs:Class ;
  rdfs:label "human subject unable to give informed consent"@en ;
  rdfs:comment "A human subject who is unable to give informed consent. In this case, another person is generally authorized to give consent on his behalf, e.g., parents or legal guardians of a child, though in this circumstance the child may be required to provide informed assent, and conservators for the mentally ill."@en ;
  rdfs:subClassOf obo:NCBITaxon_9606 .

obo:ICO_0000177 a rdfs:Class ;
  rdfs:label "consenting not to have financial benefit"@en ;
  rdfs:comment "An informed consent for a subject agrees not to have financial benefit in the future."@en ;
  rdfs:subClassOf obo:ICO_0000196 .

obo:OBI_0001942 a rdfs:Class ;
  rdfs:label "grant agency"@en ;
  rdfs:comment "An organization that provides funding support for projects such as investigations."@en ;
  rdfs:subClassOf obo:OBI_0000245 .

obo:ICO_0000012 a rdfs:Class ;
  rdfs:label "optional informed consent element"@en ;
  rdfs:comment "A document part of an informed consent form for which an answer is not required in order to complete the form."@en ;
  rdfs:subClassOf obo:IAO_0000314 .

obo:OMRSE_00000033 a rdfs:Class ;
  rdfs:label "aggregate of organizations"@en ;
  rdfs:comment "An aggregate of organizations that have some feature in common, but is not itself an organization."@en ;
  rdfs:subClassOf obo:BFO_0000040 .

obo:UBERON_0001968 a rdfs:Class ;
  rdfs:label "semen" ;
  rdfs:comment "Organism substance that is composed of sperm cells suspended in seminal fluid." ;
  rdfs:subClassOf obo:UBERON_0000463 .

<http://purl.obolibrary.org/obo/ico.owl#Belongs_in_CRO> a rdfs:Class ;
  rdfs:label "obsolete ICO Classes to Move to RUBRIC" ;
  rdfs:comment "This is a dummy class to be deprecated after it has fulfilled its organization purposes"@en ;
  rdfs:subClassOf <http://www.geneontology.org/formats/oboInOwl#ObsoleteClass> .

obo:ICO_0000122 a rdfs:Class ;
  rdfs:label "obsolete US federal policy for the protection of human subjects" ;
  rdfs:comment "A directive information entity that specifies US federal policy for the protection of human subjects."@en ;
  rdfs:subClassOf <http://www.geneontology.org/formats/oboInOwl#ObsoleteClass> .

obo:IAO_0000650 a rdfs:Class ;
  rdfs:label "database extract, transform, and load process"@en ;
  rdfs:comment "A planned process which takes as input a database and fills another database by extracting concretizations of information entities from the first, transforming them, and loading the transformed concretizations into the second."@en ;
  rdfs:subClassOf obo:OBI_0000011 .

obo:ICO_0000379 a rdfs:Class ;
  rdfs:label "designated affiliated actor"@en ;
  rdfs:comment "A 'designated actor' that designates an actor with an affilitation to an organization or institution."@en ;
  rdfs:subClassOf obo:ICO_0000325 .

obo:ICO_0000318 a rdfs:Class ;
  rdfs:label "regulatory oversight role directive"@en ;
  rdfs:comment "A role directive that prescirbes the bearer of a regulatory oversight role in a process."@en ;
  rdfs:subClassOf obo:ICO_0000316 .

obo:OBI_0000909 a rdfs:Class ;
  rdfs:label "cloacal specimen" ;
  rdfs:comment "A specimen obtained by inserting a swab deeply into the vent of the cloaca of an organism and vigorously swabbing the wall. The swab should be deeply stained with fecal material and is then placed in transport medium."@en ;
  rdfs:subClassOf obo:OBI_0001479 .

obo:ICO_0000084 a rdfs:Class ;
  rdfs:label "informed consent process with assent"@en ;
  rdfs:comment "An informed consent process that has an act of communicating assent as a process part, where the person who provides the assent does not bear a competency to consent."@en ;
  rdfs:subClassOf obo:OBI_0000810 .

obo:ICO_0000144 a rdfs:Class ;
  rdfs:label "legally effective consented participant role"@en ;
  rdfs:comment "A role that inheres in a human being who participates in a consenting process and eventually becomes legally effectively consented."@en ;
  rdfs:subClassOf obo:BFO_0000023 .

obo:IAO_0000610 a rdfs:Class ;
  rdfs:label "author summary textual entity"@en ;
  rdfs:comment "A textual entity, distinct from the abstract, that describes the significance and broader context of the document content. The author summary is often written in a non-technical manner and is aimed at both scientists and non-scientist readers, e.g as described in the article submission guidelines for PLoS Genetics (http://journals.plos.org/plosgenetics/s/submission-guidelines)."@en ;
  rdfs:subClassOf obo:IAO_0000300 .

obo:OBI_0002525 a rdfs:Class ;
  rdfs:label "tibial artery specimen" ;
  rdfs:comment "A specimen that is derived from tibial artery."@en ;
  rdfs:subClassOf obo:OBI_0001479 .

obo:IAO_0021003 a rdfs:Class ;
  rdfs:label "social act"@en ;
  rdfs:comment "A planned process that is carried out by a conscious being or an organization, and is self-generated, directed towards another conscious being or an aggregate of conscious beings, an organization or an aggregate of organizations, and that needs to be perceived."@en ;
  rdfs:subClassOf obo:OBI_0000011 .

obo:ICO_0000043 a rdfs:Class ;
  rdfs:label "permission informed consent rule specification"@en ;
  rdfs:comment "An informed consent rule specification that specifies an optional course of action that is an option for a participant to take."@en ;
  rdfs:subClassOf obo:ICO_0000041 .

obo:ICO_0000071 a rdfs:Class ;
  rdfs:label "obsolete contact person in the event of a research-related injury to the subject" ;
  rdfs:comment "A person who is the contact for questions in the event of a research-related injury to the subject"@en ;
  rdfs:subClassOf <http://www.geneontology.org/formats/oboInOwl#ObsoleteClass> .

obo:UBERON_0000002 a rdfs:Class ;
  rdfs:label "uterine cervix" ;
  rdfs:comment "Lower, narrow portion of the uterus where it joins with the top end of the vagina." ;
  rdfs:subClassOf obo:UBERON_0000465 .

obo:IAO_0000015 a rdfs:Class ;
  rdfs:label "information carrier"@en ;
  rdfs:comment "A quality of an information bearer that imparts the information content"@en ;
  rdfs:subClassOf obo:BFO_0000019 .

obo:OBI_0100016 a rdfs:Class ;
  rdfs:label "blood plasma specimen" ;
  rdfs:comment "a material entity which corresponds to the liquid component of blood, in which the blood cells are suspended."@en ;
  rdfs:subClassOf obo:OBI_0000655 , obo:OBI_0000953 .

obo:ICO_0000274 a rdfs:Class ;
  rdfs:label "description of conditional compensation"@en ;
  rdfs:comment "A descriptive information content entity that describes the conditions under which compensation is due to some agent."@en ;
  rdfs:subClassOf <http://www.ontologyrepository.com/CommonCoreOntologies/DescriptiveInformationContentEntity> .

obo:OBI_0002971 a rdfs:Class ;
  rdfs:label "endotracheal tube specimen" ;
  rdfs:comment "A specimen that derives from a biofilm that forms on the inner surface of an endotracheal tube while the tube is in the trachea. The specimen is collected upon removal of the tube from the trachea."@en ;
  rdfs:subClassOf obo:OBI_0002783 .

obo:ICO_0000155 a rdfs:Class ;
  rdfs:label "obsolete informed consent" ;
  rdfs:comment "https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3777303/"@en ;
  rdfs:subClassOf <http://www.geneontology.org/formats/oboInOwl#ObsoleteClass> .

obo:OBI_0002434 a rdfs:Class ;
  rdfs:label "HIV exclusion criterion" ;
  rdfs:comment "An exclusion criterion defined  as whether an individual has a history of repeatedly reactive screening assays for HIV-1 or HIV-2 antibody regardless of the results of supplemental assays, which if met, makes the individual unsuitable for a given task or participation in a given process."@en ;
  rdfs:subClassOf obo:OBI_0500028 .

obo:IAO_0000064 a rdfs:Class ;
  rdfs:label "algorithm"@en ;
  rdfs:comment "A plan specification which describes the inputs and output of mathematical functions as well as workflow of execution for achieving an predefined objective. Algorithms are realized usually by means of implementation as computer programs for execution by automata."@en ;
  rdfs:subClassOf obo:IAO_0000104 .

obo:ICO_0000102 a rdfs:Class ;
  rdfs:label "obsolete information sharing process" ;
  rdfs:comment "The process that shares the information under the informed consent context"@en ;
  rdfs:subClassOf <http://www.geneontology.org/formats/oboInOwl#ObsoleteClass> .

obo:ICO_0000263 a rdfs:Class ;
  rdfs:label "economic vulnerability"@en ;
  rdfs:comment "A vulnerability due to exposure to a depressed or impoverished economic environment."@en ;
  rdfs:subClassOf <http://purl.unep.org/sdg/SDGIO_00000024> .

obo:OBI_0002509 a rdfs:Class ;
  rdfs:label "sweat specimen" ;
  rdfs:comment "A specimen that is derived from sweat."@en ;
  rdfs:subClassOf obo:OBI_2000009 .

obo:IAO_0000444 a rdfs:Class ;
  rdfs:label "publishing process"@en ;
  rdfs:comment "A planned process of making information, such as literature, music, and software etc., available to the public for sale or for free."@en ;
  rdfs:subClassOf obo:OBI_0000011 .

obo:UBERON_0000310 a rdfs:Class ;
  rdfs:label "breast" ;
  rdfs:comment "The upper ventral region of the torso of an organism." ;
  rdfs:subClassOf obo:UBERON_0000465 .

obo:IAO_0021014 a rdfs:Class ;
  rdfs:label "obsolete_declaration executive role"@en ;
  rdfs:comment "The role borne by a human being, an organization or an aggregate of either of both that is realized by being the active participant in a declaration."@en ;
  rdfs:subClassOf <http://www.geneontology.org/formats/oboInOwl#ObsoleteClass> .

obo:IAO_0000704 a rdfs:Class ;
  rdfs:label "measurement methods section"@en ;
  rdfs:comment "A methods section that describes details of data assessment methods (data measurement)."@en ;
  rdfs:subClassOf obo:IAO_0000317 .

obo:IAO_0000321 a rdfs:Class ;
  rdfs:label "author list"@en ;
  rdfs:comment "A part of a document that enumerates the authors of the document"@en ;
  rdfs:subClassOf obo:IAO_0000314 .

obo:IAO_0000429 a rdfs:Class ;
  rdfs:label "email address"@en ;
  rdfs:subClassOf obo:IAO_0000030 .

obo:OBI_2000001 a rdfs:Class ;
  rdfs:label "urethra specimen" ;
  rdfs:comment "A specimen that is derived from some urethra"@en ;
  rdfs:subClassOf obo:OBI_0001479 .

obo:OBI_2000014 a rdfs:Class ;
  rdfs:label "venous blood specimen" ;
  rdfs:comment "A specimen that is derived from some venous blood"@en ;
  rdfs:subClassOf obo:OBI_0000655 .

obo:CL_0000578 a rdfs:Class ;
  rdfs:label "experimentally modified cell in vitro" ;
  rdfs:comment "A cell in vitro that has undergone physical changes as a consequence of a deliberate and specific experimental procedure." ;
  rdfs:subClassOf obo:CL_0000000 , obo:OBI_0000047 .

obo:DUO_0000037 a rdfs:Class ;
  rdfs:label "biomedical research" ;
  rdfs:comment "An investigation concerning health, medical, or biomedical research." ;
  rdfs:subClassOf obo:OBI_0000066 .

obo:OBIB_0000630 a rdfs:Class ;
  rdfs:label "department"@en ;
  rdfs:comment "An organization with a specific responsibility that is a part of a larger organization with a specific responsibility."@en ;
  rdfs:subClassOf obo:OBI_0000245 .

obo:ICO_0000095 a rdfs:Class ;
  rdfs:label "minimal risk"@en ;
  rdfs:comment "A risk that is equal or lesser than those ordinarily encountered in daily life or during the performance of routine physical or psychological examinations or tests."@en ;
  rdfs:subClassOf obo:ICO_0000078 .

obo:ICO_0000418 a rdfs:Class ;
  rdfs:label "sensitive information protection directive"@en ;
  rdfs:comment "A 'permission requirement directive' that directs sensitive infotmation proctection."@en ;
  rdfs:subClassOf obo:ICO_0000364 .

obo:OBI_2000004 a rdfs:Class ;
  rdfs:label "eye specimen" ;
  rdfs:comment "A specimen that is derived from some eye"@en ;
  rdfs:subClassOf obo:OBI_0001479 .

obo:IAO_0000186 a rdfs:Class ;
  rdfs:label "photographic print"@en ;
  rdfs:comment "A photographic print is a material entity upon which a photograph generically depends."@en ;
  rdfs:subClassOf obo:BFO_0000040 , obo:IAO_0000178 .

obo:OBI_0002781 a rdfs:Class ;
  rdfs:label "lower respiratory tract aspirate specimen" ;
  rdfs:comment "A specimen that is collected with a suctioning tube from the lower respiratory tract."@en ;
  rdfs:subClassOf obo:OBI_0002783 .

obo:OBI_0002648 a rdfs:Class ;
  rdfs:label "individual organism specimen" ;
  rdfs:comment "A specimen composed of an individual organism to be studied in an investigation."@en ;
  rdfs:subClassOf obo:OBI_0100051 .

obo:ICO_0000005 a rdfs:Class ;
  rdfs:label "signing an informed consent form"@en ;
  rdfs:comment "A social act that is a part of an informed consent process and has output of a signed informed consent form. The signing process leads to a legal obligation."@en ;
  rdfs:subClassOf obo:IAO_0021003 .

obo:ICO_0000393 a rdfs:Class ;
  rdfs:label "designated non-profit organization"@en ;
  rdfs:comment "A 'designated organization' that designated a non-profit organization."@en ;
  rdfs:subClassOf obo:ICO_0000384 .

obo:CL_0000232 a rdfs:Class ;
  rdfs:label "erythrocyte" ;
  rdfs:comment "A red blood cell. In mammals, mature erythrocytes are biconcave disks containing hemoglobin whose function is to transport oxygen." ;
  rdfs:subClassOf obo:CL_0000000 .

obo:ICO_0000405 a rdfs:Class ;
  rdfs:label "designated health services research purpose"@en ;
  rdfs:comment "A 'designated research purpose' that designates a health services research process as its end."@en ;
  rdfs:subClassOf obo:ICO_0000344 .

obo:OBI_0100026 a rdfs:Class ;
  rdfs:label "organism"@en ;
  rdfs:comment "A material entity that is an individual living system, such as animal, plant, bacteria or virus, that is capable of replicating or reproducing, growth and maintenance in the right environment. An organism may be unicellular or made up, like humans, of many billions of cells divided into specialized tissues and organs."@en ;
  rdfs:subClassOf obo:BFO_0000040 .

obo:OBI_0002503 a rdfs:Class ;
  rdfs:label "feces specimen" ;
  rdfs:comment "A specimen that is derived from feces."@en ;
  rdfs:subClassOf obo:OBI_0001479 .

obo:ICO_0000364 a rdfs:Class ;
  rdfs:label "permission requirement directive"@en ;
  rdfs:comment "A 'permission condition directive' that states an additional requirement."@en ;
  rdfs:subClassOf obo:ICO_0000327 .

obo:IAO_0000574 a rdfs:Class ;
  rdfs:label "assigning a centrally registered identifier"@en ;
  rdfs:comment "A planned process in which a new CRID is created, associated with an entity, and stored in the CRID registry thereby registering it as being associated with some entity"@en ;
  rdfs:subClassOf obo:OBI_0000011 .

obo:ICO_0000387 a rdfs:Class ;
  rdfs:label "designated for-profit organization"@en ;
  rdfs:comment "A 'designated organization' that designates a for-profit organization."@en ;
  rdfs:subClassOf obo:ICO_0000384 .

obo:ICO_0000032 a rdfs:Class ;
  rdfs:label "informed assent form for child or minor"@en ;
  rdfs:comment "An informed consent form that is adapted to the cognitive abilities and reading abilities child or minor."@en ;
  rdfs:subClassOf obo:ICO_0000085 .

obo:UBERON_0002048 a rdfs:Class ;
  rdfs:label "lung" ;
  rdfs:comment "Respiration organ that develops as an outpocketing of the esophagus." ;
  rdfs:subClassOf obo:UBERON_0000465 .

obo:OBI_0000950 a rdfs:Class ;
  rdfs:label "paraffin specimen" ;
  rdfs:comment "a specimen that is output of a paraffin storage process in which specimen is embedded in paraffin"@en ;
  rdfs:subClassOf obo:OBI_0001472 , obo:OBI_0100051 .

obo:ICO_0000169 a rdfs:Class ;
  rdfs:label "assenter role"@en ;
  rdfs:comment "a role that inheres in a human subject who participates in an assending process."@en ;
  rdfs:subClassOf obo:BFO_0000023 .

obo:ICO_0000021 a rdfs:Class ;
  rdfs:label "investigator signature section in informed consent form"@en ;
  rdfs:comment "A signature section in an informed consent form that is specified as a place to receive a signature from an investigator."@en ;
  rdfs:subClassOf obo:ICO_0000019 .

obo:OBI_1110116 a rdfs:Class ;
  rdfs:label "splenocyte specimen" ;
  rdfs:comment "A cell specimen comprised of a mixed cell population obtained by processing whole spleen into individual cells, typically performed using a sieve or blender. This population includes T cells, B cells, macrophages, and other cell types."@en ;
  rdfs:subClassOf obo:OBI_0000953 , obo:OBI_0001468 .

obo:ICO_0000329 a rdfs:Class ;
  rdfs:label "designated process of access"@en ;
  rdfs:comment "A 'designated action' that designates a process of access as permissable."@en ;
  rdfs:subClassOf obo:ICO_0000324 .

obo:ICO_0000353 a rdfs:Class ;
  rdfs:label "designated non-commercial purpose"@en ;
  rdfs:comment "A 'permission purpose directive' that designates a nonprofit activity as its end."@en ;
  rdfs:subClassOf obo:ICO_0000328 .

obo:UBERON_0007311 a rdfs:Class ;
  rdfs:label "sputum" ;
  rdfs:comment "Matter ejected from the lungs, bronchi, and trachea, through the mouth." ;
  rdfs:subClassOf obo:UBERON_0006538 .

obo:UBERON_0002371 a rdfs:Class ;
  rdfs:label "bone marrow" ;
  rdfs:comment "The soft tissue that fills the cavities of bones." ;
  rdfs:subClassOf obo:UBERON_0000479 .

obo:PR_000000001 a rdfs:Class ;
  rdfs:label "protein" ;
  rdfs:comment "An amino acid chain that is produced de novo by ribosome-mediated translation of a genetically-encoded mRNA, and any derivatives thereof." ;
  rdfs:subClassOf obo:CHEBI_16670 .

obo:IAO_0000037 a rdfs:Class ;
  rdfs:label "dot plot"@en ;
  rdfs:comment "A dot plot is a report graph which is a graphical representation of data where each data point is represented by a single dot placed on coordinates corresponding to data point values in particular dimensions."@en ;
  rdfs:subClassOf obo:IAO_0000038 .

obo:ICO_0000056 a rdfs:Class ;
  rdfs:label "nonprofit research investigation"@en ;
  rdfs:comment "An investigation that is conducted with a nonprofit purpose."@en ;
  rdfs:subClassOf obo:OBI_0000066 .

obo:ICO_0000224 a rdf:Property ;
  rdfs:label "has agent"@en ;
  rdfs:comment "A relation between an instance of Process and an instance of Continuant, where the continuant is a causal participant in the process."@en ;
  rdfs:domain obo:BFO_0000003 ;
  rdfs:range obo:BFO_0000002 ;
  rdfs:subPropertyOf obo:RO_0000057 .

obo:OBI_0000274 a rdfs:Class ;
  rdfs:label "adding a material entity into a target"@en ;
  rdfs:comment "is a process with the objective to place a material entity bearing the 'material to be added role' into a material bearing the 'target of material addition role'."@en ;
  rdfs:subClassOf obo:OBI_0000652 .

obo:ICO_0000338 a rdfs:Class ;
  rdfs:label "designated process of contact"@en ;
  rdfs:comment "A 'designated action' that designates a process of contact permissable."@en ;
  rdfs:subClassOf obo:ICO_0000324 .

obo:ICO_0000421 a rdfs:Class ;
  rdfs:label "act of data use"@en ;
  rdfs:comment "A planned process in which data is put to some use by an entity."@en ;
  rdfs:subClassOf obo:OBI_0000011 .

obo:OBI_0000671 a rdfs:Class ;
  rdfs:label "sample from organism" ;
  rdfs:comment "a material obtained from an organism in order to be a representative of the whole"@en ;
  rdfs:subClassOf obo:OBI_0000747 , obo:OBI_0001479 .

obo:DUO_0000026 a rdfs:Class ;
  rdfs:label "user specific restriction"@en ;
  rdfs:comment "This data use modifier indicates that use is limited to use by approved users."@en ;
  rdfs:subClassOf obo:DUO_0000017 .

obo:IAO_0000181 a rdfs:Class ;
  rdfs:label "Venn diagram"@en ;
  rdfs:comment """A Venn diagram is a report graph showing all hypothetically possible
logical relations between a finite collection of sets."""@en ;
  rdfs:subClassOf obo:IAO_0000038 .

obo:IAO_0000101 a rdfs:Class ;
  rdfs:label "image"@en ;
  rdfs:comment "An image is an affine projection to a two dimensional surface, of measurements of some quality of an entity or entities repeated at regular intervals across a spatial range, where the measurements are represented as color and luminosity on the projected on surface."@en ;
  rdfs:subClassOf obo:IAO_0000308 .

obo:ICO_0000124 a rdfs:Class ;
  rdfs:label "archiving signed electronic informed consent form"@en ;
  rdfs:comment "A planned process of storage of signed informed consent form when the form is in digital format."@en ;
  rdfs:subClassOf obo:OBI_0000011 .

obo:ICO_0000166 a rdfs:Class ;
  rdfs:label "obsolete deontic role" ;
  rdfs:subClassOf <http://www.geneontology.org/formats/oboInOwl#ObsoleteClass> .

obo:ICO_0000079 a rdfs:Class ;
  rdfs:label "institutional review board"@en ;
  rdfs:comment "A specially constituted organization comprised of medical, scientific and non-scientific members established and designated by an entity to ensure the protection of the rights, safety and well-being of human subjects recruited to participate in biomedical or behavioral research according to the requirements outlined in Title 38, part 16 (same as Title 45, part 46 and Title 21, part 56) of the U.S. Code of Federal Regulations. IRB responsibility include but not limited to the reviewing, approving, and providing continuing review of trial protocol and amendments and of the methods and material to be used in obtaining and documenting informed consent of the trial. Other equivalent committees with the same or similar functions are also considered to be IRBs."@en ;
  rdfs:seeAlso <http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C16741&ns=NCI_Thesaurus> ;
  rdfs:subClassOf obo:OBI_0000245 .

obo:ICO_0000285 a rdfs:Class ;
  rdfs:label "vulnerable individual role"@en ;
  rdfs:comment "A role that inheres in an agent or group of agents that is the output of a process during which the agent or group of agents is designated as belonging to a vulnerable group."@en ;
  rdfs:subClassOf obo:BFO_0000023 .

obo:ICO_0000190 a rdfs:Class ;
  rdfs:label "description of participation benefit"@en ;
  rdfs:comment "A descriptive information content entity that describes potential benefit or estimates the likelihood of benefit."@en ;
  rdfs:subClassOf <http://www.ontologyrepository.com/CommonCoreOntologies/DescriptiveInformationContentEntity> .

obo:OBI_0002560 a rdfs:Class ;
  rdfs:label "family status inclusion criterion"@en ;
  rdfs:comment "An inclusion criterion that defines and states one or more family statuses, which, if met, makes a human being suitable for a given task or participation in a given process."@en ;
  rdfs:subClassOf obo:OBI_0500027 .

obo:UBERON_0006538 a rdfs:Class ;
  rdfs:label "respiratory system fluid/secretion" ;
  rdfs:comment "A portion of organism substance that secreted_by a respiratory system." ;
  rdfs:subClassOf obo:UBERON_0000463 .

obo:OBI_0302893 a rdfs:Class ;
  rdfs:label "storage"@en ;
  rdfs:comment "A planned process with the objective to preserve and protect material entities by placing them in an identified location which may have a controlled environment."@en ;
  rdfs:subClassOf obo:OBI_0000838 .

obo:OBI_0000014 a rdfs:Class ;
  rdfs:label "regulator role"@en ;
  rdfs:comment "a regulatory role involved with making and/or enforcing relevant legislation and governmental orders"@en ;
  rdfs:subClassOf obo:OBI_0000017 .

obo:CHEBI_16670 a rdfs:Class ;
  rdfs:label "peptide" ;
  rdfs:comment "Amide derived from two or more amino carboxylic acid molecules (the same or different) by formation of a covalent bond from the carbonyl carbon of one to the nitrogen atom of another with formal loss of water. The term is usually applied to structures formed from alpha-amino acids, but it includes those derived from any amino carboxylic acid. X = OH, OR, NH2, NHR, etc." ;
  rdfs:subClassOf obo:CHEBI_33839 .

obo:ICO_0000375 a rdfs:Class ;
  rdfs:label "designated biospecimen"@en ;
  rdfs:comment "A 'designated object' that designates a biospecimen."@en ;
  rdfs:subClassOf obo:ICO_0000326 .

obo:OBI_0002546 a rdfs:Class ;
  rdfs:label "liver specimen" ;
  rdfs:comment "A specimen that is derived from liver."@en ;
  rdfs:subClassOf obo:OBI_0001479 .

obo:OBI_0002557 a rdfs:Class ;
  rdfs:label "maximum age value specification"@en ;
  rdfs:comment "A value specifcation that specifies the oldest age when specifying an age range."@en ;
  rdfs:subClassOf obo:OBI_0001933 .

obo:ICO_0000407 a rdfs:Class ;
  rdfs:label "designated control material research purpose"@en ;
  rdfs:comment "A 'designated research purpose' that designates reference control material research processes as its end."@en ;
  rdfs:subClassOf obo:ICO_0000344 .

obo:OBI_2000018 a rdfs:Class ;
  rdfs:label "leukocyte specimen" ;
  rdfs:comment "A specimen that is derived from some leukocytes"@en ;
  rdfs:subClassOf obo:OBI_0001468 .

obo:OMRSE_00000198 a rdfs:Class ;
  rdfs:label "information content entity-request process"@en ;
  rdfs:comment "a communication in which some participant requests of some other participant an information content entity about some portion of reality"@en ;
  rdfs:subClassOf obo:OMRSE_00000192 .

obo:OBI_0000434 a rdfs:Class ;
  rdfs:label "adding material objective"@en ;
  rdfs:comment "is the specification of an objective to add a material into a target material. The adding is asymmetric in the sense that the target material largely retains its identity"@en ;
  rdfs:subClassOf obo:OBI_0000686 .

obo:UO_0000001 a rdfs:Class ;
  rdfs:label "length unit" ;
  rdfs:comment "A unit which is a standard measure of the distance between two points." ;
  rdfs:subClassOf obo:IAO_0000003 .

obo:IAO_0000141 a rdfs:Class ;
  rdfs:label "obsolete_digital quality" ;
  rdfs:subClassOf <http://www.geneontology.org/formats/oboInOwl#ObsoleteClass> .

obo:ICO_0000196 a rdfs:Class ;
  rdfs:label "act of informed consenting"@en ;
  rdfs:comment "An act of permitting that is a process part of some informed consent process."@en ;
  rdfs:subClassOf obo:ICO_0000195 .

obo:OBI_0002456 a rdfs:Class ;
  rdfs:label "gravidity inclusion criterion"@en ;
  rdfs:comment "An inclusion criterion that defines and states one or more gravidity statuses of an organism, which, if met, makes the entity suitable for a given task or participation in a given process."@en ;
  rdfs:subClassOf obo:OBI_0500027 .

obo:OBI_0002550 a rdfs:Class ;
  rdfs:label "sigmoid colon specimen" ;
  rdfs:comment "A specimen that is derived from sigmoid colon."@en ;
  rdfs:subClassOf obo:OBI_0003483 .

obo:OBI_0000810 a rdfs:Class ;
  rdfs:label "informed consent process" ;
  rdfs:comment "A planned process with the objective to inform a person or their legal representative of legally and ethically relevant facts about a process that the person in question is asked to participate in, and which results in a documented decision as to whether the person in question will participate."@en ;
  rdfs:subClassOf obo:OBI_0000011 .

obo:IAO_0021007 a rdfs:Class ;
  rdfs:label "document act input document"@en ;
  rdfs:comment "A document that is intended to be the specified input in a document act. It has a plan specification as a part that specifies the intended socio-legal entities that are created through the document (objective specification) and the way in which the document act is to be performed (by signing, by stamping, etc.) (action specification)."@en ;
  rdfs:subClassOf obo:IAO_0000310 .

obo:CL_2000001 a rdfs:Class ;
  rdfs:label "peripheral blood mononuclear cell" ;
  rdfs:comment "A leukocyte with a single non-segmented nucleus in the mature form found in the circulatory pool of blood." ;
  rdfs:subClassOf obo:CL_0000842 .

obo:OBI_0002423 a rdfs:Class ;
  rdfs:label "age of majority inclusion criterion" ;
  rdfs:comment "An inclusion criterion that uses the age of majority for a state or institution, where one is generally considered to be an adult, which if met, makes an individual suitable for a given task or participation in a given process."@en ;
  rdfs:subClassOf obo:OBI_0500027 .

obo:UBERON_0000995 a rdfs:Class ;
  rdfs:label "uterus" ;
  rdfs:comment "The female muscular organ of gestation in which the developing embryo or fetus is nourished until birth." ;
  rdfs:subClassOf obo:UBERON_0000465 .

obo:IAO_0021018 a rdfs:Class ;
  rdfs:label "obsolete_obligator role"@en ;
  rdfs:comment "The role of a human being or an aggregate of human beings  concretizing an obligation."@en ;
  rdfs:subClassOf <http://www.geneontology.org/formats/oboInOwl#ObsoleteClass> .

obo:OGMS_0000018 a rdfs:Class ;
  rdfs:label "laboratory finding" ;
  rdfs:comment "A representation of a quality of a specimen that is the output of a laboratory test and that can support an inference to an assertion about some quality of the patient."@en ;
  rdfs:subClassOf obo:OGMS_0000014 .

obo:IAO_0000621 a rdfs:Class ;
  rdfs:label "ethical approval textual entity"@en ;
  rdfs:comment "A textual entity that documents the ethical approval of some study design."@en ;
  rdfs:subClassOf obo:IAO_0000300 .

obo:UBERON_0036149 a rdfs:Class ;
  rdfs:label "suprapubic skin" ;
  rdfs:comment "Area of skin in the hypoastric region of the abdomen." ;
  rdfs:subClassOf obo:UBERON_0000465 .

obo:ICO_0000416 a rdfs:Class ;
  rdfs:label "designated recruitment purpose"@en ;
  rdfs:comment "A 'permission purpose directive' that designates a process of recruitment."@en ;
  rdfs:subClassOf obo:ICO_0000328 .

obo:IAO_0000637 a rdfs:Class ;
  rdfs:label "pre-publication history section"@en ;
  rdfs:comment "A part of the document about the publication history of a document. This section typically details dates of document submission to a journal and dates of any re-submissions as well as reviewer comments and responses to reviewers by the authors."@en ;
  rdfs:subClassOf obo:IAO_0000314 .

obo:BFO_0000019 a rdfs:Class ;
  rdfs:label "quality"@en ;
  rdfs:subClassOf obo:BFO_0000020 .

obo:OBI_0001000 a rdfs:Class ;
  rdfs:label "questionnaire" ;
  rdfs:comment "A document with a set of printed or written questions with a choice of answers, devised for the purposes of a survey or statistical study."@en ;
  rdfs:subClassOf obo:IAO_0000310 .

obo:UBERON_0000057 a rdfs:Class ;
  rdfs:label "urethra" ;
  rdfs:comment "The fibromuscular tubular canal through which urine is discharged from the bladder to the exterior via the external urinary meatus; in males, the urethra is joined by the ejaculatory ducts and serves as a passageway for semen during ejaculation, as well as a canal for urine during voiding; in females, the urethra is shorter and emerges above the vaginal opening." ;
  rdfs:subClassOf obo:UBERON_0000465 .

obo:ICO_0000342 a rdfs:Class ;
  rdfs:label "designated process of surveillance" ;
  rdfs:comment "A 'designated action' that designates a process of surveillance."@en ;
  rdfs:subClassOf obo:ICO_0000324 .

obo:ICO_0000236 a rdfs:Class ;
  rdfs:label "informed consent rule"@en ;
  rdfs:comment "A rule in an informed consent regulatory document that prescribes either an informed consent process or deontic roles inhering in agents that participate in an informed consent process."@en ;
  rdfs:subClassOf obo:IAO_0000055 .

obo:NCIT_C70800 a rdfs:Class ;
  rdfs:label "Institutional Review Board Approval" ;
  rdfs:comment "A document containing the determination of the Institutional Review Board (IRB) that the clinical study with human subject participation has been reviewed and may be conducted at a particular study site within the constraints set forth by the IRB and other institutional and federal requirements. The regulations require that an IRB conduct continuing review of research at intervals appropriate to the degree of risk, but not less than once a year." ;
  rdfs:subClassOf obo:IAO_0000310 .

obo:ICO_0000111 a rdfs:Class ;
  rdfs:label "review board approval number"@en ;
  rdfs:comment "A character string that is assigned by a review board upon approval of a regulatory document."@en ;
  rdfs:subClassOf obo:IAO_0000028 .

obo:OBI_0002521 a rdfs:Class ;
  rdfs:label "renal medulla specimen" ;
  rdfs:comment "A specimen that is derived from renal medulla."@en ;
  rdfs:subClassOf obo:OBI_0001479 .

obo:IAO_0000582 a rdfs:Class ;
  rdfs:label "time stamped measurement datum"@en ;
  rdfs:subClassOf obo:IAO_0000109 .

obo:IAO_0000581 a rdf:Property ;
  rdfs:label "has time stamp"@en ;
  rdfs:comment "relates a time stamped measurement datum to the time measurement datum that denotes the time when the measurement was taken"@en ;
  rdfs:domain obo:IAO_0000582 ;
  rdfs:range obo:IAO_0000416 ;
  rdfs:subPropertyOf obo:BFO_0000051 .

obo:IAO_0000583 a rdf:Property ;
  rdfs:label "has measurement datum"@en ;
  rdfs:comment "relates a time stamped measurement datum to the measurement datum that was measured"@en ;
  rdfs:domain obo:IAO_0000582 ;
  rdfs:range <https://w3id.org/linkml/Any> ;
  rdfs:subPropertyOf obo:BFO_0000051 .

obo:ICO_0000073 a rdfs:Class ;
  rdfs:label "research subject role"@en ;
  rdfs:comment "A role that inheres in human being and is an output of some participation in a research study."@en ;
  rdfs:subClassOf obo:BFO_0000023 .

obo:ICO_0000147 a rdfs:Class ;
  rdfs:label "candidate eligible for study role"@en ;
  rdfs:comment "A role inhering in a participant who meets all eligibility criteria defined within a study protocol."@en ;
  rdfs:subClassOf obo:BFO_0000023 .

obo:ICO_0000382 a rdfs:Class ;
  rdfs:label "designated principal investigator"@en ;
  rdfs:comment "A 'designated actor' that designates a principal investigator."@en ;
  rdfs:subClassOf obo:ICO_0000325 .

obo:ICO_0000054 a rdfs:Class ;
  rdfs:label "human research investigation"@en ;
  rdfs:comment "An investigation that involves human research."@en ;
  rdfs:subClassOf obo:OBI_0000066 .

obo:BFO_0000035 a rdfs:Class ;
  rdfs:label "process boundary"@en ;
  rdfs:comment "p is a process boundary =Def. p is a temporal part of a process & p has no proper temporal parts. (axiom label in BFO2 Reference: [084-001])"@en ;
  rdfs:subClassOf obo:BFO_0000003 .

<http://www.geneontology.org/formats/oboInOwl#ObsoleteClass> a rdfs:Class ;
  rdfs:label "Obsolete Class" .

obo:ICO_0000390 a rdfs:Class ;
  rdfs:label "designated healthcare organization"@en ;
  rdfs:comment "A 'designated organization' that designates a healthcare organization."@en ;
  rdfs:subClassOf obo:ICO_0000384 .

obo:OBI_0002650 a rdfs:Class ;
  rdfs:label "biopsy" ;
  rdfs:comment "A specimen collection that obtains a sample of tissue or cell from a living multicellular organism body for diagnostic purposes by means intended to be minimally invasive."@en ;
  rdfs:subClassOf obo:OBI_0600005 .

obo:ICO_0000229 a rdfs:Class ;
  rdfs:label "human subject-specified contact person role"@en ;
  rdfs:comment "A contact person role that is the output of either a human subject or patient assigning that person as their point of contact."@en ;
  rdfs:subClassOf obo:ICO_0000230 .

obo:ICO_0000117 a rdfs:Class ;
  rdfs:label "explaining study protocol to participant candidate"@en ;
  rdfs:comment "In order to make sure that the candidate is informed adequately from his or her perspective, the protocol of the study including the protocol of participating, for example, what kind of procedure the participant will be involved, how many scheduled visits will be explained."@en ;
  rdfs:subClassOf obo:ICO_0000154 .

obo:IAO_0000615 a rdfs:Class ;
  rdfs:label "conclusion section"@en ;
  rdfs:comment "A part of a document used to summarize the findings discussed in the document. The conclusion section is typically found near the end of a document."@en ;
  rdfs:subClassOf obo:IAO_0000314 .

obo:ICO_0000215 a rdfs:Class ;
  rdfs:label "deontic power role"@en ;
  rdfs:comment "A deontic role that, if realized, is realized in the creation, modification, or revoking of other deontic roles."@en ;
  rdfs:subClassOf obo:IAO_0021008 .

obo:IAO_0000025 a rdfs:Class ;
  rdfs:label "programming language"@en ;
  rdfs:comment "A language in which source code is written that is intended to be executed/run by a software interpreter. Programming languages are ways to write instructions that specify what to do, and sometimes, how to do it."@en ;
  rdfs:subClassOf obo:IAO_0000104 .

obo:NCBITaxon_32523 a rdfs:Class ;
  rdfs:label "Tetrapoda" ;
  rdfs:subClassOf obo:NCBITaxon_117571 .

obo:IAO_0021008 a rdfs:Class ;
  rdfs:label "deontic role"@en ;
  rdfs:comment "A role that inheres in an agent and which is externally grounded in the normative expectations that other agents within a social context have concerning how that agent should behave."@en ;
  rdfs:subClassOf obo:BFO_0000023 .

obo:IAO_0000311 a rdfs:Class ;
  rdfs:label "publication"@en ;
  rdfs:comment "A document that is the output of a publishing process."@en ;
  rdfs:subClassOf obo:IAO_0000310 .

obo:OBI_0000834 a rdfs:Class ;
  rdfs:label "high molecular weight DNA extract" ;
  rdfs:comment "The output of an extraction process in which DNA molecules above a molecular weight cutoff are purified in order to exclude DNA from organellas."@en ;
  rdfs:subClassOf obo:OBI_0001051 .

obo:IAO_0000047 a rdfs:Class ;
  rdfs:label "obsolete2_text based digital entity"@en ;
  rdfs:comment "A text based digital entity is a digital entity that is encoded so that it only contains text characters."@en ;
  rdfs:subClassOf <http://www.geneontology.org/formats/oboInOwl#ObsoleteClass> .

obo:OBI_1200000 a rdfs:Class ;
  rdfs:label "FFPE specimen" ;
  rdfs:comment "A specimen that has been fixed in formalin and embedded in paraffin."@en ;
  rdfs:subClassOf obo:OBI_0000950 .

obo:ICO_0000125 a rdfs:Class ;
  rdfs:label "archiving signed scanned paper informed consent form"@en ;
  rdfs:comment "A process of storage of signed informed consent form when the form is in digital format."@en ;
  rdfs:subClassOf obo:ICO_0000120 .

obo:OGMS_0000096 a rdfs:Class ;
  rdfs:label "health care process" ;
  rdfs:comment "A planned process with the objective to improve the health status of a patient that directly involves the treatment, diagnosis, or prevention of disease or injury of a patient"@en ;
  rdfs:subClassOf obo:OBI_0000011 .

obo:ICO_0000397 a rdfs:Class ;
  rdfs:label "designated unspecified organization"@en ;
  rdfs:comment "A 'designated organization' that designates an unspecified organization."@en ;
  rdfs:subClassOf obo:ICO_0000384 .

obo:OBI_0000379 a rdfs:Class ;
  rdfs:label "mechanical function"@en ;
  rdfs:comment "A mechanical function is a function that is realised via mechanical work (through an certain amount of energy transferred by some force)."@en ;
  rdfs:subClassOf obo:BFO_0000034 .

obo:IAO_0000632 a rdfs:Class ;
  rdfs:label "study limitations textual entity"@en ;
  rdfs:comment "A textual entity addressing a shortcoming or bias of a study design or execution."@en ;
  rdfs:subClassOf obo:IAO_0000300 .

obo:ICO_0000325 a rdfs:Class ;
  rdfs:label "designated actor"@en ;
  rdfs:comment "A 'Designative Information Content Entity' that designates an entity which can bear deontic roles."@en ;
  rdfs:subClassOf <http://www.ontologyrepository.com/CommonCoreOntologies/DesignativeInformationContentEntity> .

obo:OBI_0000686 a rdfs:Class ;
  rdfs:label "material combination objective" ;
  rdfs:comment "is an objective to obtain an output material that contains several input materials."@en ;
  rdfs:subClassOf obo:OBI_0000456 .

obo:IAO_0000008 a rdfs:Class ;
  rdfs:label "obsolete_artifact" ;
  rdfs:subClassOf <http://www.geneontology.org/formats/oboInOwl#ObsoleteClass> .

obo:OBI_0000151 a rdfs:Class ;
  rdfs:label "filter paper" ;
  rdfs:comment "A device manufacture with the intent to provide a porous unsized paper used for filtering."@en ;
  rdfs:subClassOf obo:OBI_0000932 .

obo:IAO_0000144 a rdfs:Class ;
  rdfs:label "conclusion textual entity"@en ;
  rdfs:comment "A textual entity that expresses the results of reasoning about a problem, for instance as typically found towards the end of scientific papers."@en ;
  rdfs:subClassOf obo:IAO_0000300 .

obo:ICO_0000367 a rdfs:Class ;
  rdfs:label "designated data"@en ;
  rdfs:comment "A 'designated object' that designates data or information."@en ;
  rdfs:subClassOf obo:ICO_0000326 .

obo:ICO_0000162 a rdfs:Class ;
  rdfs:label "tissue sample collecting"@en ;
  rdfs:comment "A biological sample collecting in which a tissue sample from a subject is collected for testing."@en ;
  rdfs:subClassOf obo:ICO_0000161 .

obo:IAO_8000016 a rdfs:Class ;
  rdfs:label "taxonomic bridge ontology module"@en ;
  rdfs:subClassOf obo:IAO_8000004 .

obo:IAO_0020023 a rdfs:Class ;
  rdfs:label "authentication"@en ;
  rdfs:comment """Authentication is the act of checking or verifying an identity claim (that is either tacit or explicit).
"""@en ;
  rdfs:subClassOf obo:BFO_0000015 .

obo:IAO_0000643 a rdfs:Class ;
  rdfs:label "statistical analysis textual entity"@en ;
  rdfs:comment "A textual entity documenting statistical analysis tools and techniques employed."@en ;
  rdfs:subClassOf obo:IAO_0000300 .

obo:DUO_0000043 a rdfs:Class ;
  rdfs:label "clinical care use"@en ;
  rdfs:comment "This data use modifier indicates that use is allowed for clinical use and care."@en ;
  rdfs:subClassOf obo:DUO_0000017 .

obo:OBI_0002774 a rdfs:Class ;
  rdfs:label "platelet-poor plasma specimen" ;
  rdfs:comment "A blood plasma specimen that is the output of some platelet-poor plasma preparation and is the portion of plasma that contains fewer than 10,000 platelets per microliter."@en ;
  rdfs:subClassOf obo:OBI_0100016 .

obo:OBI_0002520 a rdfs:Class ;
  rdfs:label "heart specimen" ;
  rdfs:comment "A specimen that is derived from heart."@en ;
  rdfs:subClassOf obo:OBI_0001479 .

obo:ICO_0000360 a rdfs:Class ;
  rdfs:label "jurisdiction restriction directive"@en ;
  rdfs:comment "A 'permission restriction directive' that defines the spatial boundaries of a 'designated action'."@en ;
  rdfs:subClassOf obo:ICO_0000357 .

obo:UBERON_8470000 a rdfs:Class ;
  rdfs:label "placental blood" ;
  rdfs:comment "Blood located in the placenta." ;
  rdfs:subClassOf obo:UBERON_0000178 .

obo:ICO_0000049 a rdfs:Class ;
  rdfs:label "profit organization"@en ;
  rdfs:comment "An organization which has the principle goal of earning financial profit."@en ;
  rdfs:subClassOf obo:OBI_0000245 .

obo:IAO_0000096 a rdfs:Class ;
  rdfs:label "source code module"@en ;
  rdfs:comment "A source code module is a directive information entity that specifies, using a programming language, some algorithm."@en ;
  rdfs:subClassOf obo:IAO_0000033 .

obo:ICO_0000241 a rdfs:Class ;
  rdfs:label "obsolete confidentiality directive" ;
  rdfs:comment "A directive information entity that prescribes the limits of disclosure regarding an agent’s identity."@en ;
  rdfs:subClassOf <http://www.geneontology.org/formats/oboInOwl#ObsoleteClass> .

obo:UBERON_0001323 a rdfs:Class ;
  rdfs:label "tibial nerve" ;
  rdfs:comment "The tibial nerve is a branch of the sciatic nerve. The tibial nerve passes through the popliteal fossa to pass below the arch of soleus. In the popliteal fossa the nerve gives off branches to gastrocnemius, popliteus, soleus and plantaris muscles, an articular branch to the knee joint, and a cutaneous branch that will become the sural nerve. The sural nerve is joined by fibres from the common peroneal nerve and runs down the calf to supply the lateral side of the foot. Below the soleus muscle the nerve lies close to the tibia and supplies the tibialis posterior, the flexor digitorum longus and the flexor hallucis longus. The nerve passes into the foot running posterior to the medial malleolus. Here it is bound down by the flexor retinaculum in company with the posterior tibial artery. [WP,unvetted]." ;
  rdfs:subClassOf obo:UBERON_0000465 .

obo:ICO_0000128 a rdfs:Class ;
  rdfs:label "explaining risks of participation to participant candidate"@en ;
  rdfs:comment "The potential future harm that may arise from participating the study research is to be explained to candidate"@en ;
  rdfs:subClassOf obo:ICO_0000154 .

obo:ICO_0000237 a rdfs:Class ;
  rdfs:label "conditional informed consent rule"@en ;
  rdfs:comment "A rule in an informed consent regulatory document that prescribes an informed consent process and has part trigger condition description."@en ;
  rdfs:subClassOf obo:IAO_0000055 .

obo:topic_0003 a rdfs:Class ;
  rdfs:label "Topic" ;
  rdfs:comment "A category denoting a rather broad domain or field of interest, study, application, work, data, or technology. Topics have no clearly defined borders between each other." ;
  rdfs:subClassOf obo:IAO_0000030 .

obo:IAO_0000591 a rdfs:Class ;
  rdfs:label "software method"@en ;
  rdfs:comment "A software method (also called subroutine, subprogram, procedure, method, function, or routine) is software designed to execute a specific task."@en ;
  rdfs:subClassOf obo:IAO_0000010 .

obo:OGMS_0000014 a rdfs:Class ;
  rdfs:label "clinical finding" ;
  rdfs:comment "A representation that is either the output of a clinical history taking or a physical examination or an image finding, or some combination thereof."@en ;
  rdfs:subClassOf obo:IAO_0000027 .

obo:BFO_0000020 a rdfs:Class ;
  rdfs:label "specifically dependent continuant"@en ;
  rdfs:comment "A continuant that inheres in or is borne by other entities. Every instance of A requires some specific instance of B which must always be the same."@en ;
  rdfs:subClassOf obo:BFO_0000002 .

obo:OMRSE_00000056 a rdfs:Class ;
  rdfs:label "hospital organization"@en ;
  rdfs:comment "An organization that is the bearer of a hospital role."@en ;
  rdfs:subClassOf obo:OBI_0000245 .

obo:UBERON_0002106 a rdfs:Class ;
  rdfs:label "spleen" ;
  rdfs:comment "The organ that functions to filter blood and to store red corpuscles and platelets." ;
  rdfs:subClassOf obo:UBERON_0000465 .

obo:UBERON_0000481 a rdfs:Class ;
  rdfs:label "multi-tissue structure" ;
  rdfs:comment "Anatomical structure that has as its parts two or more portions of tissue of at least two different types and which through specific morphogenetic processes forms a single distinct structural unit demarcated by bona-fide boundaries from other distinct structural units of different types." ;
  rdfs:subClassOf obo:UBERON_0000465 .

obo:ICO_0000010 a rdfs:Class ;
  rdfs:label "option to check" ;
  rdfs:comment "An answer directive that is part of a document and whose filling in or leaving blank is incidental to the completion of the form."@en ;
  rdfs:subClassOf obo:ICO_0000242 .

obo:OBI_1110041 a rdfs:Class ;
  rdfs:label "lymph node cell specimen" ;
  rdfs:comment "A cell specimen comprised of a mixed population of cells obtained by processing whole lymph node into individual cells, typically performed using a sieve. This population includes T cells, B cells, macrophages, and other cell types."@en ;
  rdfs:subClassOf obo:OBI_0000953 , obo:OBI_0001468 .

obo:OBI_0002526 a rdfs:Class ;
  rdfs:label "skin of body specimen" ;
  rdfs:comment "A specimen that is derived from skin."@en ;
  rdfs:subClassOf obo:OBI_0001479 .

obo:IAO_0000329 a rdfs:Class ;
  rdfs:label "running title"@en ;
  rdfs:comment "A shorter version of a document title"@en ;
  rdfs:subClassOf obo:IAO_0000305 .

obo:ICO_0000376 a rdfs:Class ;
  rdfs:label "designated residual tissue"@en ;
  rdfs:comment "A 'designated biospecimen' that designates a portion of excess tissue."@en ;
  rdfs:subClassOf obo:ICO_0000375 .

obo:CHEBI_33696 a rdfs:Class ;
  rdfs:label "nucleic acid" ;
  rdfs:comment "A macromolecule made up of nucleotide units and hydrolysable into certain pyrimidine or purine bases (usually adenine, cytosine, guanine, thymine, uracil), D-ribose or 2-deoxy-D-ribose and phosphoric acid." ;
  rdfs:subClassOf obo:CHEBI_33839 .

obo:IAO_8000001 a rdfs:Class ;
  rdfs:label "base ontology module"@en ;
  rdfs:comment "An ontology module that comprises only of asserted axioms local to the ontology, excludes import directives, and excludes axioms or declarations from external ontologies."@en ;
  rdfs:seeAlso <https://github.com/INCATools/ontology-starter-kit/issues/50> ;
  rdfs:subClassOf obo:IAO_8000000 .

obo:ICO_0000068 a rdfs:Class ;
  rdfs:label "obsolete general requirement for informed consent" ;
  rdfs:subClassOf <http://www.geneontology.org/formats/oboInOwl#ObsoleteClass> .

obo:OBI_0002746 a rdfs:Class ;
  rdfs:label "induced sputum specimen" ;
  rdfs:comment "A sputum specimen that is collected from an organism following its inhalation of a nebulized salt solution."@en ;
  rdfs:subClassOf obo:OBI_0002508 .

obo:ICO_0000371 a rdfs:Class ;
  rdfs:label "designated identifiable information"@en ;
  rdfs:comment "A 'designated data' that designates information that may identify an entity."@en ;
  rdfs:subClassOf obo:ICO_0000367 .

obo:DUO_0000032 a rdfs:Class ;
  rdfs:label "population research" ;
  rdfs:comment "An investigation concerning a specific population group." ;
  rdfs:subClassOf obo:OBI_0000066 .

obo:CHEBI_33839 a rdfs:Class ;
  rdfs:label "macromolecule" ;
  rdfs:comment "A macromolecule is a molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass." ;
  rdfs:subClassOf obo:CHEBI_23367 .

obo:IAO_0000185 a rdfs:Class ;
  rdfs:label "photograph"@en ;
  rdfs:comment "A photograph is created by projecting an image onto a photosensitive surface such as a chemically treated plate or film, CCD receptor, etc."@en ;
  rdfs:subClassOf obo:IAO_0000101 .

obo:ICO_0000303 a rdfs:Class ;
  rdfs:label "description of research procedure"@en ;
  rdfs:comment "A descriptive information content entity that describes a research procedure."@en ;
  rdfs:subClassOf <http://www.ontologyrepository.com/CommonCoreOntologies/DescriptiveInformationContentEntity> .

obo:DUO_0000021 a rdfs:Class ;
  rdfs:label "ethics approval required"@en ;
  rdfs:comment "This data use modifier indicates that the requestor must provide documentation of local IRB/ERB approval."@en ;
  rdfs:subClassOf obo:DUO_0000017 .

obo:IAO_8000012 a rdfs:Class ;
  rdfs:label "species subset ontology module"@en ;
  rdfs:comment "A subset ontology that is crafted to either include or exclude a taxonomic grouping of species."@en ;
  rdfs:seeAlso <https://github.com/obophenotype/uberon/wiki/Taxon-constraints> ;
  rdfs:subClassOf obo:IAO_8000006 .

obo:OBI_0000066 a rdfs:Class ;
  rdfs:label "investigation"@en ;
  rdfs:comment "a planned process that consists of parts: planning, study design execution, documentation and which produce conclusion(s)."@en ;
  rdfs:subClassOf obo:OBI_0000011 .

obo:ICO_0000123 a rdfs:Class ;
  rdfs:label "act of storing signed informed consent form" ;
  rdfs:comment "An act of storing a complete informed consent form."@en ;
  rdfs:subClassOf obo:ICO_0000227 .

obo:OBI_0002427 a rdfs:Class ;
  rdfs:label "radiation treatment within the recent past exclusion criterion" ;
  rdfs:comment "An exclusion criterion that defines whether radiation was received within a certain timeframe, which when met, makes an individual unsuitable for a given task or participation in a given process."@en ;
  rdfs:subClassOf obo:OBI_0500028 .

obo:APOLLO_SV_00000796 a rdfs:Class ;
  rdfs:label "dataset creating"@en ;
  rdfs:comment "A planned process that has a data set as its specified output."@en ;
  rdfs:subClassOf obo:OBI_0000011 .

obo:ICO_0000034 a rdfs:Class ;
  rdfs:label "informed consent form for clinical research involving children"@en ;
  rdfs:comment "An informed consent form for clinical study that involves children."@en .

obo:IAO_0000578 a rdfs:Class ;
  rdfs:label "centrally registered identifier"@en ;
  rdfs:comment "An information content entity that consists of a CRID symbol and additional information about the CRID registry to which it belongs."@en ;
  rdfs:subClassOf obo:IAO_0020000 .

obo:ICO_0000427 a rdfs:Class ;
  rdfs:label "owner role directive"@en ;
  rdfs:comment "A directive information entity that prescribes the owner role."@en ;
  rdfs:subClassOf obo:IAO_0000033 .

obo:DUO_0000015 a rdfs:Class ;
  rdfs:label "no general methods research"@en ;
  rdfs:comment "This data use modifier indicates that use does not allow methods development research (e.g., development of software or algorithms)."@en ;
  rdfs:subClassOf obo:DUO_0000017 .

obo:ICO_0000081 a rdfs:Class ;
  rdfs:label "legal guardian role"@en ;
  rdfs:comment "A role that inheres in an individual who is authorized under applicable State or local law to consent on behalf of a child or incapable person to general medical care including participation in clinical research."@en ;
  rdfs:subClassOf obo:BFO_0000023 .

obo:ICO_0000386 a rdfs:Class ;
  rdfs:label "designated biobank organization"@en ;
  rdfs:comment "A 'designated organization' that designates a biobank organization."@en ;
  rdfs:subClassOf obo:ICO_0000384 .

obo:ICO_0000365 a rdfs:Class ;
  rdfs:label "permission sub-directive"@en ;
  rdfs:comment "A 'permission condition directive' that directs another 'consent directive' as a requirement of a primary 'consent directive'."@en ;
  rdfs:subClassOf obo:ICO_0000327 .

obo:ICO_0000310 a rdfs:Class ;
  rdfs:label "directive about research of biospecimens"@en ;
  rdfs:comment "A directive information entity that prescribes some investigation of biospecimens."@en ;
  rdfs:subClassOf obo:IAO_0000033 .

obo:NCBITaxon_2759 a rdfs:Class ;
  rdfs:label "Eukaryota" ;
  rdfs:subClassOf obo:OBI_0100026 .

obo:ICO_0000394 a rdfs:Class ;
  rdfs:label "designated public health organization"@en ;
  rdfs:comment "A 'designated organization' that designates a public health organization."@en ;
  rdfs:subClassOf obo:ICO_0000384 .

obo:IAO_0000079 a rdfs:Class ;
  rdfs:label "density plot"@en ;
  rdfs:comment "A density plot is a report graph which is a graphical representation of data where the tint of a particular pixel corresponds to some kind of function corresponding the the amount of data points relativelly with their distance from the the pixel."@en ;
  rdfs:subClassOf obo:IAO_0000038 .

obo:UBERON_0006618 a rdfs:Class ;
  rdfs:label "atrium auricular region" ;
  rdfs:comment "A small conical pouch projections located on the upper anterior portion of each atrium of the heart." ;
  rdfs:subClassOf obo:UBERON_0000481 .

obo:ICO_0000193 a rdfs:Class ;
  rdfs:label "act of filling out form"@en ;
  rdfs:comment "A planned process of providing information according to prompts on a form."@en ;
  rdfs:subClassOf obo:OBI_0000011 .

obo:ICO_0000045 a rdfs:Class ;
  rdfs:label "investigator role"@en ;
  rdfs:comment "A role borne by an agent that, if realized, is realized in an investigation."@en ;
  rdfs:subClassOf obo:BFO_0000023 .

obo:UBERON_0001004 a rdfs:Class ;
  rdfs:label "respiratory system" ;
  rdfs:comment "Functional system which consists of structures involved in respiration." ;
  rdfs:subClassOf obo:UBERON_0000465 .

obo:IAO_0000626 a rdfs:Class ;
  rdfs:label "future directions textual entity"@en ;
  rdfs:comment "A textual entity expressing ideas regarding future work relevant to work described in a document that could be done."@en ;
  rdfs:subClassOf obo:IAO_0000300 .

obo:UBERON_0001970 a rdfs:Class ;
  rdfs:label "bile" ;
  rdfs:comment "Vital aqueous secretion of the liver that is formed by hepatocytes and modified down stream by absorptive and secretory properties of the bile duct epithelium." ;
  rdfs:subClassOf obo:UBERON_0006314 .

obo:OMRSE_00000087 a rdfs:Class ;
  rdfs:label "employer role"@en ;
  rdfs:comment "a role in human social processes that is realized when the bearer provides a wage or salary in exchange for some labour or services as specified by some declaration"@en ;
  rdfs:subClassOf obo:OMRSE_00000024 .

obo:ICO_0000354 a rdfs:Class ;
  rdfs:label "designated therapeutic purpose"@en ;
  rdfs:comment "A 'permission purpose directive' that designates a process related to healing a disease as its end."@en ;
  rdfs:subClassOf obo:ICO_0000328 .

obo:OBI_0002514 a rdfs:Class ;
  rdfs:label "peritoneal fluid specimen" ;
  rdfs:comment "A specimen that is derived from peritoneal fluid."@en ;
  rdfs:subClassOf obo:OBI_2000009 .

obo:IAO_0000619 a rdfs:Class ;
  rdfs:label "consent textual entity"@en ;
  rdfs:comment "A textual entity that documents the consenting process used to enroll patients in a study."@en ;
  rdfs:subClassOf obo:IAO_0000300 .

obo:OBI_0100060 a rdfs:Class ;
  rdfs:label "cultured cell population" ;
  rdfs:comment "A processed material comprised of a collection of cultured cells that has been continuously maintained together in culture and shares a common propagation history."@en ;
  rdfs:subClassOf obo:OBI_0000047 .

obo:UBERON_0000029 a rdfs:Class ;
  rdfs:label "lymph node" ;
  rdfs:comment "Any of the rounded masses of lymphoid tissue that are surrounded by a capsule of connective tissue, are distributed along the lymphatic vessels, and contain numerous lymphocytes which filter the flow of lymph." ;
  rdfs:subClassOf obo:UBERON_0000465 .

obo:OBI_0000245 a rdfs:Class ;
  rdfs:label "organization"@en ;
  rdfs:comment "An entity that can bear roles, has members, and has a set of organization rules. Members of organizations are either organizations themselves or individual people. Members can bear specific organization member roles that are determined in the organization rules. The organization rules also determine how decisions are made on behalf of the organization by the organization members."@en ;
  rdfs:subClassOf obo:ICO_0000220 .

obo:ICO_0000429 a rdfs:Class ;
  rdfs:label "residual clinical biospecimen"@en ;
  rdfs:comment "A material entity, collected during some health care process, that bears both a specimen role and an excess material role following some act of artifact modification."@en ;
  rdfs:subClassOf obo:BFO_0000040 .

obo:IAO_0021020 a rdfs:Class ;
  rdfs:label "obsolete_declaration target"@en ;
  rdfs:comment "The human being or organization or aggregate of any of the aforementioned that is the bearer of a concretization of a socio-legal generically dependent continuant brought about by or transferred in a specific document act."@en ;
  rdfs:subClassOf <http://www.geneontology.org/formats/oboInOwl#ObsoleteClass> .

obo:ICO_0000330 a rdfs:Class ;
  rdfs:label "designated process of analysis"@en ;
  rdfs:comment "A 'designated action' that designates a process of analysis as permissable."@en ;
  rdfs:subClassOf obo:ICO_0000324 .

obo:ICO_0000248 a rdfs:Class ;
  rdfs:label "obligation directive"@en ;
  rdfs:comment "A directive information entity that prescribes an obligation that is realized a deontic role that is the output of a document act."@en ;
  rdfs:subClassOf obo:IAO_0000033 .

obo:ICO_0000348 a rdfs:Class ;
  rdfs:label "designated diagnostic purpose"@en ;
  rdfs:comment "A 'permission purpose directive' that designates a process of diagnosis as its end."@en ;
  rdfs:subClassOf obo:ICO_0000328 .

obo:ICO_0000259 a rdfs:Class ;
  rdfs:label "description of alternative"@en ;
  rdfs:comment "A descriptive information content entity that describes some process that may be elected."@en ;
  rdfs:subClassOf <http://www.ontologyrepository.com/CommonCoreOntologies/DescriptiveInformationContentEntity> .

obo:OBI_0002539 a rdfs:Class ;
  rdfs:label "tibial nerve specimen" ;
  rdfs:comment "A specimen that is derived from tibial nerve."@en ;
  rdfs:subClassOf obo:OBI_0001479 .

obo:ICO_0000038 a rdfs:Class ;
  rdfs:label "project starting date specification"@en ;
  rdfs:comment "A date specification that designates the date when a project begins."@en ;
  rdfs:subClassOf obo:ICO_0000022 .

obo:ICO_0000410 a rdfs:Class ;
  rdfs:label "designated drug research purpose"@en ;
  rdfs:comment "A 'designated biomedical research purpose' that designates a process of drug research as its end."@en ;
  rdfs:subClassOf obo:ICO_0000345 .

obo:UBERON_0001987 a rdfs:Class ;
  rdfs:label "placenta" ;
  rdfs:comment "Organ of metabolic interchange between fetus and mother, partly of embryonic origin and partly of maternal origin[GO]. The fetal portion of the placenta is known as the villous chorion. The maternal portion is known as the decidua basalis. The two portions are held together by anchoring villi that are anchored to the decidua basalis by the cytotrophoblastic shell." ;
  rdfs:subClassOf obo:UBERON_0000465 .

obo:ICO_0000133 a rdfs:Class ;
  rdfs:label "explaining sample process and usage to participant candidate"@en ;
  rdfs:comment "In order to make sure that the candidate is informed adequately from his or her perspective, the process of collecting, storing or destroying the sample collected from the study subject is to be explained."@en ;
  rdfs:subClassOf obo:ICO_0000154 .

obo:OBI_0003054 a rdfs:Class ;
  rdfs:label "blood specimen in vacutainer" ;
  rdfs:comment "A blood specimen that is located in a vacutainer."@en ;
  rdfs:subClassOf obo:OBI_0000655 .

obo:ICO_0000202 a rdfs:Class ;
  rdfs:label "competency to consent"@en ;
  rdfs:comment "A capability to consent that is sufficiently robust as to pass the legal requirements of some jurisdiction."@en ;
  rdfs:subClassOf obo:ICO_0000201 .

obo:OBI_0000855 a rdfs:Class ;
  rdfs:label "total RNA extraction" ;
  rdfs:comment "A RNA extraction process in which total cellular and organelle RNA are extracted."@en ;
  rdfs:subClassOf obo:OBI_0666666 .

obo:ICO_0000230 a rdfs:Class ;
  rdfs:label "contact person role"@en ;
  rdfs:comment "A role inhering in a person who is a designated contact for some other agent."@en ;
  rdfs:subClassOf obo:BFO_0000023 .

obo:OBI_0002600 a rdfs:Class ;
  rdfs:label "collecting specimen with swab" ;
  rdfs:comment "A specimen collection process that uses a swab as the collection device. A swab is an absorbent material (e.g. cotton) on a rod (e.g., wooden stick)."@en ;
  rdfs:subClassOf obo:OBI_0000659 .

obo:UBERON_0000970 a rdfs:Class ;
  rdfs:label "eye" ;
  rdfs:comment "An organ that detects light." ;
  rdfs:subClassOf obo:UBERON_0000465 .

obo:ICO_0000252 a rdfs:Class ;
  rdfs:label "trigger condition directive"@en ;
  rdfs:comment "A directive information entity that describes some state of affairs such that, if that state of affairs holds, some other prescription follows."@en ;
  rdfs:subClassOf obo:IAO_0000033 .

obo:OBIB_0000039 a rdfs:Class ;
  rdfs:label "blood specimen on blood spot card"@en ;
  rdfs:comment "A blood specimen that is located on a blood spot card." ;
  rdfs:subClassOf obo:OBI_0000655 .

obo:ICO_0000101 a rdfs:Class ;
  rdfs:label "health information entity"@en ;
  rdfs:comment "An information content entity which is created or received by a health care provider, health plan, public health authority, employer, life insurer, school or university, or health care clearinghouse; and relates to the past, present, or future physical or mental health or condition of any individual, the provision of health care to an individual, or the past, present, or future payment for the provision of health care to an individual."@en ;
  rdfs:subClassOf obo:IAO_0000030 .

obo:ICO_0000096 a rdfs:Class ;
  rdfs:label "obsolete alcohol abuse treatment record" ;
  rdfs:comment "A medical record that records the history of a subject's treatment for alcohol abuse."@en ;
  rdfs:subClassOf <http://www.geneontology.org/formats/oboInOwl#ObsoleteClass> .

obo:OBI_0000849 a rdfs:Class ;
  rdfs:label "organellar RNA extraction" ;
  rdfs:comment "A RNA extraction process in which the desired output material is RNA in the organelle(s)."@en ;
  rdfs:subClassOf obo:OBI_0666666 .

obo:OBI_0000444 a rdfs:Class ;
  rdfs:label "target of material addition role"@en ;
  rdfs:comment "A role of a material entity that is realized in an \"adding a material entity into a target\" process where the bearer of the role (the target) receives the addition of another material entity."@en ;
  rdfs:subClassOf obo:BFO_0000023 .

obo:CHMO_0002845 a rdfs:Class ;
  rdfs:label "waste management" ;
  rdfs:comment "A planned process that involves all aspects of dealing with the waste produced in experiments." ;
  rdfs:subClassOf obo:OBI_0000011 .

obo:OBI_0302886 a rdfs:Class ;
  rdfs:label "centrifugation"@en ;
  rdfs:comment "centrifugation is a process separating molecules by size or density using centrifugal forces generated by a spinning rotor. G-forces of several hundred thousand times gravity are generated in ultracentrifugation"@en ;
  rdfs:subClassOf obo:OBI_0600014 .

obo:IAO_0000305 a rdfs:Class ;
  rdfs:label "document title"@en ;
  rdfs:comment "A textual entity that names a document"@en ;
  rdfs:subClassOf obo:IAO_0000300 .

obo:OMRSE_00000015 a rdfs:Class ;
  rdfs:label "health care provider organization role"@en ;
  rdfs:comment "A role that inheres in an organization and that is realized by the providing of services in a health care encounter."@en ;
  rdfs:subClassOf obo:OMRSE_00000027 .

obo:ICO_0000136 a rdfs:Class ;
  rdfs:label "participant candidate making voluntary decision of acceptance"@en ;
  rdfs:comment "A process in which a candidate makes a voluntary decision to join a study, following their consideration of adequate information presented to them regarding the study and their participation in it."@en ;
  rdfs:subClassOf obo:BFO_0000015 .

obo:UBERON_0000463 a rdfs:Class ;
  rdfs:label "organism substance" ;
  rdfs:comment "Material anatomical entity in a gaseous, liquid, semisolid or solid state; produced by anatomical structures or derived from inhaled and ingested substances that have been modified by anatomical structures as they pass through the body." ;
  rdfs:subClassOf obo:UBERON_0000465 .

obo:ICO_0000023 a rdfs:Class ;
  rdfs:label "completely filled informed consent form"@en ;
  rdfs:comment "An informed consent form that has been filled with all required contents."@en .

obo:OBI_0000339 a rdfs:Class ;
  rdfs:label "planning"@en ;
  rdfs:comment "a process of creating or modifying a plan specification"@en ;
  rdfs:subClassOf obo:BFO_0000015 .

obo:OBI_0000806 a rdfs:Class ;
  rdfs:label "material maintenance objective" ;
  rdfs:comment "An objective specification maintains some or all of the qualities of a material over time."@en ;
  rdfs:subClassOf obo:IAO_0000005 .

obo:UBERON_0002367 a rdfs:Class ;
  rdfs:label "prostate gland" ;
  rdfs:comment "The prostate gland is a partly muscular, partly glandular body that is situated near the base of the mammalian male urethra and secretes an alkaline viscid fluid which is a major constituent of the ejaculatory fluid." ;
  rdfs:subClassOf obo:UBERON_0000465 .

obo:ICO_0000139 a rdfs:Class ;
  rdfs:label "obsolete Walgreens vaccine informed consent form'" ;
  rdfs:comment "An informed consent form that is used for vaccination by Walgreens"@en ;
  rdfs:subClassOf <http://www.geneontology.org/formats/oboInOwl#ObsoleteClass> .

obo:ICO_0000114 a rdfs:Class ;
  rdfs:label "obsolete anonymized genomic data" ;
  rdfs:comment "An anonymized data item that is about a genomic sample."@en ;
  rdfs:subClassOf <http://www.geneontology.org/formats/oboInOwl#ObsoleteClass> .

obo:ICO_0000356 a rdfs:Class ;
  rdfs:label "permission precondition"@en ;
  rdfs:comment "A 'permission condition directive' which states a preceding event or condition."@en ;
  rdfs:subClassOf obo:ICO_0000327 .

obo:IAO_0021031 a rdfs:Class ;
  rdfs:label "document act performer role"@en ;
  rdfs:comment "A role inhering in a human being or an organization or an aggregate of any of the aforementioned that is realized by the bearer being the agent in a document act."@en ;
  rdfs:subClassOf obo:BFO_0000023 .

obo:IAO_8000005 a rdfs:Class ;
  rdfs:label "import ontology module"@en ;
  rdfs:comment "A subset ontology module that is intended to be imported from another ontology."@en ;
  rdfs:seeAlso <http://robot.obolibrary.org/extract> ;
  rdfs:subClassOf obo:IAO_8000006 .

obo:ICO_0000314 a rdfs:Class ;
  rdfs:label "investigation objective specification"@en ;
  rdfs:comment "An objective specification whose intended process endpoint is an investigation."@en ;
  rdfs:subClassOf obo:IAO_0000005 .

obo:IAO_0000019 a rdfs:Class ;
  rdfs:label "obsolete2_binary digital entity"@en ;
  rdfs:comment "A binary digital entity is a digital entity that is encoded in a way that is not easily human readable and that contains other than text characters."@en ;
  rdfs:subClassOf <http://www.geneontology.org/formats/oboInOwl#ObsoleteClass> .

obo:ICO_0000307 a rdfs:Class ;
  rdfs:label "waiver directive"@en ;
  rdfs:comment "A directive information entity that prescribes an act of waiving."@en ;
  rdfs:subClassOf obo:IAO_0000033 .

obo:ICO_0000151 a rdfs:Class ;
  rdfs:label "eligibility screening role" ;
  rdfs:comment "A role that inheres in a person that, if realized, is realized in an eligibility screening process."@en ;
  rdfs:subClassOf obo:BFO_0000023 .

obo:IAO_0000003 a rdfs:Class ;
  rdfs:label "measurement unit label"@en ;
  rdfs:comment "A measurement unit label is as a label that is part of a scalar measurement datum and denotes a unit of measure."@en ;
  rdfs:subClassOf obo:IAO_0000009 .

obo:UBERON_0002469 a rdfs:Class ;
  rdfs:label "esophagus mucosa" ;
  rdfs:comment "A mucosa that is part of a esophagus [Automatically generated definition]." ;
  rdfs:subClassOf obo:UBERON_0000465 .

obo:OBI_2000011 a rdfs:Class ;
  rdfs:label "meconium specimen" ;
  rdfs:comment "A specimen that is derived from some meconium"@en ;
  rdfs:subClassOf obo:OBI_0002503 .

obo:OBI_0000914 a rdfs:Class ;
  rdfs:label "nasopharyngeal aspirate specimen" ;
  rdfs:comment "A specimen which derives from nasopharyngeal mucosa after aspiration."@en ;
  rdfs:subClassOf obo:OBI_2000007 .

obo:IAO_0000109 a rdfs:Class ;
  rdfs:label "measurement datum"@en ;
  rdfs:comment "A measurement datum is an information content entity that is a recording of the output of a measurement such as produced by a device."@en ;
  rdfs:subClassOf obo:IAO_0000027 .

obo:ICO_0000017 a rdfs:Class ;
  rdfs:label "obsolete fully signed informed consent form" ;
  rdfs:comment "An informed consent form that has been signed by all participants."@en ;
  rdfs:subClassOf <http://www.geneontology.org/formats/oboInOwl#ObsoleteClass> .

obo:DUO_0000004 a rdfs:Class ;
  rdfs:label "no restriction"@en ;
  rdfs:comment "This data use permission indicates there is no restriction on use."@en ;
  rdfs:subClassOf obo:DUO_0000001 .

obo:ICO_0000140 a rdfs:Class ;
  rdfs:label "eligibility questionnaire"@en ;
  rdfs:comment "A questionnaire whose purpose is to aid in identifying whether an agent is eligible to participate in a process."@en ;
  rdfs:subClassOf obo:OBI_0001000 .

obo:ICO_0000106 a rdfs:Class ;
  rdfs:label "obsolete legal name" ;
  rdfs:comment "Legal name is the person name that identifies a person for legal, administrative and other official purposes. A person&apos;s first legal name generally is the name of the person that was given for the purpose of registration of the birth and which then appears on a birth certificate (see birth name), but may change subsequently."@en ;
  rdfs:subClassOf <http://www.geneontology.org/formats/oboInOwl#ObsoleteClass> .

obo:DUO_0000019 a rdfs:Class ;
  rdfs:label "publication required"@en ;
  rdfs:comment "This data use modifier indicates that requestor agrees to make results of studies using the data available to the larger scientific community."@en ;
  rdfs:subClassOf obo:DUO_0000017 .

obo:OMRSE_00000022 a rdfs:Class ;
  rdfs:label "collection of organisms"@en ;
  rdfs:comment "An object aggregate of organisms."@en ;
  rdfs:subClassOf obo:BFO_0000040 .

obo:IAO_0000608 a rdfs:Class ;
  rdfs:label "author information textual entity"@en ;
  rdfs:comment "A textual entity expression information about an author of a document. This information may include biographical information and may discuss how the authors' professional experiences are relevant to the work described in the document."@en ;
  rdfs:subClassOf obo:IAO_0000300 .

obo:ICO_0000359 a rdfs:Class ;
  rdfs:label "permitted actor restriction directive"@en ;
  rdfs:comment "A 'permission restriction directive' that designates an actor."@en ;
  rdfs:subClassOf obo:ICO_0000357 .

obo:ICO_0000345 a rdfs:Class ;
  rdfs:label "designated biomedical research purpose"@en ;
  rdfs:comment "A 'designated research purpose' that designates a biomedical research process as its end."@en ;
  rdfs:subClassOf obo:ICO_0000344 .

obo:IAO_0000648 a rdfs:Class ;
  rdfs:label "zone improvement plan code"@en ;
  rdfs:comment "A postal code that is used in the United States for the purpose of sorting and delivering mail, and that denotes some postal delivery route or some aggregate of postal delivery routes."@en ;
  rdfs:subClassOf obo:IAO_0000646 .

obo:OBI_0002972 a rdfs:Class ;
  rdfs:label "endotracheal aspirate specimen" ;
  rdfs:comment "A specimen that derives from a biofilm that forms on the inner surface of an endotracheal tube while the tube is in the trachea. The specimen is collected by suction without removing the tube."@en ;
  rdfs:subClassOf obo:OBI_0002781 .

obo:ICO_0000116 a rdfs:Class ;
  rdfs:label "act of using study participant data"@en ;
  rdfs:comment "A planned process that involves using data which was an output of a human being's participation in a study and which is about that human being."@en ;
  rdfs:subClassOf obo:ICO_0000421 .

obo:IAO_0000102 a rdfs:Class ;
  rdfs:label "data about an ontology part"@en ;
  rdfs:comment "Data about an ontology part is a data item about a part of an ontology, for example a term"@en ;
  rdfs:subClassOf obo:IAO_0000027 .

obo:ICO_0000269 a rdfs:Class ;
  rdfs:label "act of communicating"@en ;
  rdfs:comment "A planned process in which some entity provides information to another entity."@en ;
  rdfs:subClassOf obo:IAO_0021003 .

obo:OBI_0002429 a rdfs:Class ;
  rdfs:label "blood transfusion exclusion criterion" ;
  rdfs:comment "An exclusion criterion that is defined by whether the specimen donor received a whole blood transfusion within a specified time frame prior to death, which if met, makes a specimen donor unsuitable for a given task or participation in a given process."@en ;
  rdfs:subClassOf obo:OBI_0500028 .

obo:UBERON_0001723 a rdfs:Class ;
  rdfs:label "tongue" ;
  rdfs:comment "A muscular organ in the floor of the mouth." ;
  rdfs:subClassOf obo:UBERON_0000465 .

obo:ICO_0000374 a rdfs:Class ;
  rdfs:label "designated human object"@en ;
  rdfs:comment "A 'designated object' that designates a person, or part of a person, as the target of a 'designated action.'"@en ;
  rdfs:subClassOf obo:ICO_0000326 .

obo:OBI_0100017 a rdfs:Class ;
  rdfs:label "blood serum specimen" ;
  rdfs:comment "A material entity which derives from blood and corresponds to blood plasma without fibrinogen or the other clotting factors."@en ;
  rdfs:subClassOf obo:OBI_0100016 .

obo:IAO_0000575 a rdfs:Class ;
  rdfs:label "associating information with a centrally registered identifier in its registry"@en ;
  rdfs:comment "A planned process in which a CRID registry associates an information content entity with a CRID symbol"@en ;
  rdfs:subClassOf obo:OBI_0000011 .

obo:OBI_0001364 a rdfs:Class ;
  rdfs:label "genetic alteration information"@en ;
  rdfs:comment "a genetic characteristics information that is about known changes or the lack thereof from the genetic background, including allele information, duplication, insertion, deletion, etc."@en ;
  rdfs:subClassOf obo:OBI_0001404 .

obo:OBI_0002528 a rdfs:Class ;
  rdfs:label "stomach specimen" ;
  rdfs:comment "A specimen that is derived from stomach."@en ;
  rdfs:subClassOf obo:OBI_0003483 .

obo:ICO_0000168 a rdfs:Class ;
  rdfs:label "obsolete genetic research permission deontic declaration" ;
  rdfs:comment "A deontic declaration that has output a permittee role that permits genetic research on a human donor as a specified outcome."@en ;
  rdfs:subClassOf <http://www.geneontology.org/formats/oboInOwl#ObsoleteClass> .

obo:UBERON_0001728 a rdfs:Class ;
  rdfs:label "nasopharynx" ;
  rdfs:comment "The section of the pharynx that lies above the soft palate." ;
  rdfs:subClassOf obo:UBERON_0000465 .

obo:ICO_0000105 a rdfs:Class ;
  rdfs:label "explaining study purpose to participant candidate"@en ;
  rdfs:comment "As a partial process of inform the candidate about the study participating information, the purpose of the study will be explained to make sure that the candidate is informed adequately from his/her perspective."@en ;
  rdfs:subClassOf obo:ICO_0000154 .

obo:OBI_0002559 a rdfs:Class ;
  rdfs:label "hospital patient inclusion criterion"@en ;
  rdfs:comment "An inclusion criterion defines that a human being has to be a hospital patient to be suitable for a given task or participation in a given process."@en ;
  rdfs:subClassOf obo:OBI_0500027 .

obo:ICO_0000235 a rdfs:Class ;
  rdfs:label "informed consent regulatory document"@en ;
  rdfs:comment "A regulatory document designed to prescribe an informed consent process or inputs in an informed consent process."@en ;
  rdfs:subClassOf obo:ICO_0000233 .

obo:IAO_0000038 a rdfs:Class ;
  rdfs:label "graph"@en ;
  rdfs:comment "A diagram that presents one or more tuples of information by mapping those tuples in to a two dimensional space in a non arbitrary way."@en ;
  rdfs:subClassOf obo:IAO_0000309 .

obo:ICO_0000089 a rdfs:Class ;
  rdfs:label "actual duration of study subject participation"@en ;
  rdfs:comment "Total length of time of subject's participation in a clinical study; from the time of enrollment to the completion of follow-up."@en ;
  rdfs:subClassOf obo:BFO_0000008 .

obo:IAO_8000004 a rdfs:Class ;
  rdfs:label "bridge ontology module"@en ;
  rdfs:comment "An ontology module that consists entirely of axioms that connect or bridge two distinct ontology modules. For example, the Uberon-to-ZFA bridge module."@en ;
  rdfs:seeAlso <https://github.com/obophenotype/uberon/wiki/inter-anatomy-ontology-bridge-ontologies> ;
  rdfs:subClassOf obo:IAO_8000000 .

obo:ICO_0000286 a rdfs:Class ;
  rdfs:label "regulatory oversight role"@en ;
  rdfs:comment "A role that inheres in a regulatory body that, if realized, is realized in some act of regulatory supervision."@en ;
  rdfs:subClassOf obo:BFO_0000023 .

obo:ICO_0000157 a rdfs:Class ;
  rdfs:label "parental informed consent process"@en ;
  rdfs:comment "An informed consent process in which a parent reaches a decision concerning whether or not to grant consent on a minor's behalf, when the minor is incapable of providing consent for themselves."@en ;
  rdfs:subClassOf obo:OBI_0000810 .

obo:ICO_0000138 a rdfs:Class ;
  rdfs:label "informed consent form for vaccination"@en ;
  rdfs:comment "An informed consent form that contains sections specific to procedures in vaccination."@en .

obo:ICO_0000334 a rdfs:Class ;
  rdfs:label "designated process of disclosure"@en ;
  rdfs:comment "A 'designated action' that designates a process of disclosure as permissable."@en ;
  rdfs:subClassOf obo:ICO_0000324 .

obo:OBI_0002574 a rdfs:Class ;
  rdfs:label "RNA extraction with polyA depletion" ;
  rdfs:comment "A RNA extraction process in which only RNAs lacking a polyA tail are retained"@en ;
  rdfs:subClassOf obo:OBI_0666666 .

obo:ICO_0000004 a rdfs:Class ;
  rdfs:label "approving an informed consent form"@en ;
  rdfs:comment "A planned process that approves an informed consent form."@en ;
  rdfs:subClassOf obo:OBI_0000011 .

obo:OBI_0002506 a rdfs:Class ;
  rdfs:label "pericardial fluid specimen" ;
  rdfs:comment "A specimen that is derived from pericardial fluid."@en ;
  rdfs:subClassOf obo:OBI_2000009 .

obo:ICO_0000315 a rdfs:Class ;
  rdfs:label "secondary use objective specification"@en ;
  rdfs:comment "An objective specification that prescribes the participation of an information content entity or a material entity in a process prescirbed by a future invesitgation objective specification."@en ;
  rdfs:subClassOf obo:IAO_0000005 .

obo:IAO_0000638 a rdfs:Class ;
  rdfs:label "pre-publication history textual entity"@en ;
  rdfs:comment "A textual entity that expresses the pre-publication history (submission dates, reviewer comments, etc) for a document, often including a hyperlink to a web page detailing the information."@en ;
  rdfs:subClassOf obo:IAO_0000300 .

obo:UBERON_0002107 a rdfs:Class ;
  rdfs:label "liver" ;
  rdfs:comment "An exocrine gland which secretes bile and functions in metabolism of protein and carbohydrate and fat, synthesizes substances involved in the clotting of the blood, synthesizes vitamin A, detoxifies poisonous substances, stores glycogen, and breaks down worn-out erythrocytes[GO]." ;
  rdfs:subClassOf obo:UBERON_0000465 .

obo:OMIABIS_0000052 a rdfs:Class ;
  rdfs:label "fixed tissue slide specimen"@en ;
  rdfs:comment "A fixed tissue specimen that is placed in a slide."@en ;
  rdfs:subClassOf obo:OMIABIS_0000050 .

obo:ICO_0000419 a rdfs:Class ;
  rdfs:label "designated process of treatment"@en ;
  rdfs:comment "A 'designated action' that designates a process fo treament."@en ;
  rdfs:subClassOf obo:ICO_0000324 .

obo:UBERON_0000479 a rdfs:Class ;
  rdfs:label "tissue" ;
  rdfs:comment "Multicellular anatomical structure that consists of many cells of one or a few types, arranged in an extracellular matrix such that their long-range organisation is at least partly a repetition of their short-range organisation." ;
  rdfs:subClassOf obo:UBERON_0000465 .

obo:IAO_8000009 a rdfs:Class ;
  rdfs:label "single layer subset ontology module"@en ;
  rdfs:comment "A subset ontology that is largely comprised of a single layer or strata in an ontology class hierarchy. The purpose is typically for rolling up for visualization. The classes in the layer need not be disjoint."@en ;
  rdfs:subClassOf obo:IAO_8000006 .

obo:OBI_0002553 a rdfs:Class ;
  rdfs:label "uterus specimen" ;
  rdfs:comment "A specimen that is derived from uterus."@en ;
  rdfs:subClassOf obo:OBI_0001479 .

obo:OBI_0000924 a rdfs:Class ;
  rdfs:label "labeled specimen" ;
  rdfs:comment "A specimen  that has been modified in order to be able to detect it in future experiments"@en ;
  rdfs:subClassOf obo:OBI_0000953 , obo:OBI_0001936 , obo:OBI_0100051 .

obo:ICO_0000352 a rdfs:Class ;
  rdfs:label "designated healthcare operation purpose"@en ;
  rdfs:comment "A 'permission purpose directive' that designates a healthcare operation process as its end."@en ;
  rdfs:subClassOf obo:ICO_0000328 .

obo:ICO_0000297 a rdfs:Class ;
  rdfs:label "stasis of regulation"@en ;
  rdfs:comment "A stasis of generically dependent continuant that has participant some information content entity and during which that information content entity is recognized within that jurisdiction and directs governance within that jurisdiction."@en ;
  rdfs:subClassOf <http://www.ontologyrepository.com/CommonCoreOntologies/StasisOfGenericallyDependentContinuant> .

obo:OBI_0000971 a rdfs:Class ;
  rdfs:label "fresh specimen" ;
  rdfs:comment "a specimen that is output of a specimen creation process used for an investigation without storage."@en ;
  rdfs:subClassOf obo:OBI_0001472 .

obo:ICO_0000339 a rdfs:Class ;
  rdfs:label "designated process of retention"@en ;
  rdfs:comment "A 'designated action' that designates a process of retention as permissable."@en ;
  rdfs:subClassOf obo:ICO_0000324 .

obo:IAO_0000605 a rdfs:Class ;
  rdfs:label "abbreviation textual entity"@en ;
  rdfs:comment "A textual entity listing abbreviations and their expansions that are used in a document."@en ;
  rdfs:subClassOf obo:IAO_0000300 .

<http://purl.unep.org/sdg/SDGIO_00000024> a rdfs:Class ;
  rdfs:label "vulnerability"@en ;
  rdfs:comment "A disposition of an entity to undergo undesirable change in response to some exposure."@en ;
  rdfs:subClassOf obo:BFO_0000016 .

obo:ICO_0000242 a rdfs:Class ;
  rdfs:label "user input directive"@en ;
  rdfs:comment "A directive information entity that, when signed, stamped, or initialed realizes a deontic role as described by the document specifications, or specifications in another related document."@en ;
  rdfs:subClassOf obo:IAO_0000033 .

obo:IAO_0000010 a rdfs:Class ;
  rdfs:label "software"@en ;
  rdfs:comment """Software is a plan specification composed of a series of instructions that can be 
interpreted by or directly executed by a processing unit."""@en ;
  rdfs:subClassOf obo:IAO_0000104 .

obo:ICO_0000027 a rdfs:Class ;
  rdfs:label "starting date specification in informed consent form"@en ;
  rdfs:comment "A date specification in an informed consent form that specifies the starting date of an investigation."@en ;
  rdfs:subClassOf obo:ICO_0000022 .

obo:ICO_0000381 a rdfs:Class ;
  rdfs:label "designated institution"@en ;
  rdfs:comment "A 'designated actor' that designates an institution."@en ;
  rdfs:subClassOf obo:ICO_0000325 .

obo:OBI_0002606 a rdfs:Class ;
  rdfs:label "nasopharyngeal swab specimen" ;
  rdfs:comment "A specimen that is collected with a swab from the surface of a nasopharynx."@en ;
  rdfs:subClassOf obo:OBI_0002599 , obo:OBI_2000007 .

obo:OBI_0002513 a rdfs:Class ;
  rdfs:label "placenta specimen" ;
  rdfs:comment "A specimen that is derived from placenta."@en ;
  rdfs:subClassOf obo:OBI_0001479 .

obo:IAO_0000032 a rdfs:Class ;
  rdfs:label "scalar measurement datum"@en ;
  rdfs:comment "A scalar measurement datum is a measurement datum that is composed of two parts, numerals and a unit label."@en ;
  rdfs:subClassOf obo:IAO_0000109 .

obo:IAO_0021002 a rdfs:Class ;
  rdfs:label "obsolete_document act"@en ;
  rdfs:comment "A social act creating, revoking or transferring a socio-legal generically dependent continuant or a role by validating (signing, stamping, publishing) a document."@en ;
  rdfs:subClassOf <http://www.geneontology.org/formats/oboInOwl#ObsoleteClass> .

obo:UBERON_0000947 a rdfs:Class ;
  rdfs:label "aorta" ;
  rdfs:comment "The main trunk of the systemic arterial system that carries blood from the heart to all the organs and other structures of the body, bringing oxygenated blood to all parts of the body in the systemic circulation." ;
  rdfs:subClassOf obo:UBERON_0000465 .

obo:ICO_0000013 a rdfs:Class ;
  rdfs:label "informed consent form for human biospecimen collection"@en ;
  rdfs:comment "An informed consent form that documents a voluntary decision to deposit a human biospecimen."@en .

obo:OBI_0002554 a rdfs:Class ;
  rdfs:label "vagina specimen" ;
  rdfs:comment "A specimen that is derived from vagina."@en ;
  rdfs:subClassOf obo:OBI_0001479 .

obo:ICO_0000191 a rdfs:Class ;
  rdfs:label "obsolete description of allowed action types" ;
  rdfs:comment "A document part that describes the action types to be permitted."@en ;
  rdfs:subClassOf <http://www.geneontology.org/formats/oboInOwl#ObsoleteClass> .

obo:DUO_0000039 a rdfs:Class ;
  rdfs:label "drug development research" ;
  rdfs:comment "Biomedical research concerning drug development." ;
  rdfs:subClassOf obo:DUO_0000037 .

obo:OBI_0600052 a rdfs:Class ;
  rdfs:label "dialysis"@en ;
  rdfs:comment "a protocol application that uses diffusion through a semi-permeable membrane to separate an input material into two fractions of different composition"@en ;
  rdfs:subClassOf obo:OBI_0600014 .

obo:ICO_0000392 a rdfs:Class ;
  rdfs:label "designated media organization"@en ;
  rdfs:comment "A 'designated organization' that designates a media organization."@en ;
  rdfs:subClassOf obo:ICO_0000384 .

obo:ICO_0000163 a rdfs:Class ;
  rdfs:label "blood sample collecting"@en ;
  rdfs:comment "A biological sample collecting in which a blood sample from a subject is collected for testing."@en ;
  rdfs:subClassOf obo:ICO_0000161 .

obo:OBI_0000917 a rdfs:Class ;
  rdfs:label "nasal swab specimen" ;
  rdfs:comment "A specimen obtained using a cotton swab on a stick, passed up the nostril to obtain a sample of exudate and epithelial debris for microbiological or cellular examination."@en ;
  rdfs:subClassOf obo:OBI_0002599 , obo:OBI_2000006 .

obo:OBI_0302885 a rdfs:Class ;
  rdfs:label "filtration"@en ;
  rdfs:comment "filtration is a process which separates components suspended in a fluid based on granularity properties relying on a filter device"@en ;
  rdfs:subClassOf obo:OBI_0600014 .

obo:OBI_0000093 a rdfs:Class ;
  rdfs:label "patient role"@en ;
  rdfs:comment "a role which inheres in a person and is realized by the process of being under the care of a physician or health care provider"@en ;
  rdfs:subClassOf obo:BFO_0000023 .

obo:SO_0000001 a rdfs:Class ;
  rdfs:label "region" ;
  rdfs:comment "A sequence_feature with an extent greater than zero. A nucleotide region is composed of bases and a polypeptide region is composed of amino acids." ;
  rdfs:subClassOf obo:BFO_0000031 .

obo:OBI_0002424 a rdfs:Class ;
  rdfs:label "chemotherapy treatment exclusion criterion" ;
  rdfs:comment "An exclusion criterion that defines whether chemotherapy was received or is being received for a previous  or current cancer, which when met, makes an individual unsuitable for a given task or participation in a given process"@en ;
  rdfs:subClassOf obo:OBI_0500028 .

obo:ICO_0000341 a rdfs:Class ;
  rdfs:label "designated process of study"@en ;
  rdfs:comment "A 'designated action' that designates a process of study as permissable."@en ;
  rdfs:subClassOf obo:ICO_0000324 .

obo:IAO_0000624 a rdfs:Class ;
  rdfs:label "funding source declaration textual entity"@en ;
  rdfs:comment "A textual entity documenting the source of funding that supported some study."@en ;
  rdfs:subClassOf obo:IAO_0000300 .

obo:OBI_0002125 a rdfs:Class ;
  rdfs:label "H&E-stained fixed tissue slide specimen" ;
  rdfs:comment "A fixed tissue slide specimen that is the output of H&E slide staining."@en ;
  rdfs:subClassOf obo:OMIABIS_0000052 .

obo:ICO_0000304 a rdfs:Class ;
  rdfs:label "description of future data use"@en ;
  rdfs:comment "A descriptive information content entity that describes how data will be used."@en ;
  rdfs:subClassOf obo:ICO_0000305 .

obo:IAO_0000703 a rdfs:Class ;
  rdfs:label "research participants section"@en ;
  rdfs:comment "A document part that describes human subject(s) that participated in a study (e.g. inclusion & exclusion criteria, recruitment methods, reasons for non-participation, grouping and randomisation, methods of follow-up, etc.)."@en ;
  rdfs:subClassOf obo:IAO_0000314 .

obo:OOSTT_00000062 a rdfs:Class ;
  rdfs:label "hospital governing body role"@en ;
  rdfs:comment "A role that inheres in an organization and that, if realized, is realized by its bearer overseeing the overall operation of a hospital."@en ;
  rdfs:subClassOf obo:BFO_0000023 .

obo:OBI_0002430 a rdfs:Class ;
  rdfs:label "history of metastatic cancer exclusion criterion" ;
  rdfs:comment "An exclusion criterion defined as whether an individual has ever been diagnosed with metastatic cancer (cancer that spread beyond the initial site such as to other organs like brain bone or liver), which if met, makes the individual unsuitable for a given task or participation in a given process."@en ;
  rdfs:subClassOf obo:OBI_0500028 .

obo:ICO_0000363 a rdfs:Class ;
  rdfs:label "temporal restriction directive"@en ;
  rdfs:comment "A 'permission restriction directive' that designates the temporal boundaries of the 'designated action'."@en ;
  rdfs:subClassOf obo:ICO_0000357 .

obo:IAO_0000631 a rdfs:Class ;
  rdfs:label "study limitations section"@en ;
  rdfs:comment "A part of a document about biases or short comings related to the study design and execution."@en ;
  rdfs:subClassOf obo:IAO_0000314 .

obo:APOLLO_SV_00000008 a rdfs:Class ;
  rdfs:label "software development"@en ;
  rdfs:comment "A planned process that has specified output a software product and that involves the creation of source code."@en ;
  rdfs:subClassOf obo:OBI_0000011 .

obo:OBI_0002548 a rdfs:Class ;
  rdfs:label "omentum specimen" ;
  rdfs:comment "A specimen that is derived from omentum."@en ;
  rdfs:subClassOf obo:OBI_0001479 .

obo:OBI_0000112 a rdfs:Class ;
  rdfs:label "specimen role"@en ;
  rdfs:comment "A role borne by a material entity that is obtained during a specimen collection process and that can be realized by performing measurements or observations on the specimen."@en ;
  rdfs:subClassOf obo:BFO_0000023 .

obo:OBI_0002543 a rdfs:Class ;
  rdfs:label "atrial appendage specimen" ;
  rdfs:comment "A specimen that is derived from the atrium auricular region."@en ;
  rdfs:subClassOf obo:OBI_0001479 .

obo:OBI_0002531 a rdfs:Class ;
  rdfs:label "cortex of kidney specimen" ;
  rdfs:comment "A specimen that is derived from cortex of kidney."@en ;
  rdfs:subClassOf obo:OBI_0001479 .

obo:OBI_0000895 a rdfs:Class ;
  rdfs:label "total RNA extract" ;
  rdfs:comment "A RNA extract that is the output of an extraction process in which total celluar and organelle RNA molecules are isolated from a specimen."@en ;
  rdfs:subClassOf obo:OBI_0000880 .

obo:ICO_0000408 a rdfs:Class ;
  rdfs:label "designated populations research purpose"@en ;
  rdfs:comment "A 'designated research purpose' that designates a process of population research as its end."@en ;
  rdfs:subClassOf obo:ICO_0000344 .

obo:ICO_0000090 a rdfs:Class ;
  rdfs:label "obsolete credential letter" ;
  rdfs:comment "A document that certifies that 1) a person may perform some action, or 2) which provides authentication for a claim, or 3) which confirms position or status."@en ;
  rdfs:subClassOf <http://www.geneontology.org/formats/oboInOwl#ObsoleteClass> .

obo:OBI_0302716 a rdfs:Class ;
  rdfs:label "pool of specimens" ;
  rdfs:comment "A pool of specimens is a mixture of a population of samples which have been gathered from one or more sample populations, obtained by the physical process of mixing individual specimens, e.g.  mixing the DNA collected from the individual fish."@en ;
  rdfs:subClassOf obo:OBI_0000953 , obo:OBI_0100051 .

obo:IAO_0000034 a rdfs:Class ;
  rdfs:label "time trigger"@en ;
  rdfs:subClassOf obo:IAO_0000001 .

obo:UBERON_0002032 a rdfs:Class ;
  rdfs:label "areola" ;
  rdfs:comment "Subdivision of breast which consists of skin, connective tissue and smooth muscle bundle and modified sebaceous glands and which surrounds the nipple." ;
  rdfs:subClassOf obo:UBERON_0000465 .

obo:IAO_0021102 a rdfs:Class ;
  rdfs:label "standing declaration"@en ;
  rdfs:comment "A social act that postulates a socio-legal fact for a specified group of people or organizations."@en ;
  rdfs:subClassOf obo:IAO_0021003 .

obo:ICO_0000220 a rdfs:Class ;
  rdfs:label "agent"@en ;
  rdfs:comment "A material entity (either a human being or an aggregate of humans such as an organization) which is active in a process or has the relevant capabilities of intentionality."@en ;
  rdfs:subClassOf obo:BFO_0000040 .

obo:BFO_0000148 a rdfs:Class ;
  rdfs:label "zero-dimensional temporal region"@en ;
  rdfs:subClassOf obo:BFO_0000008 .

obo:OBI_0000202 a rdfs:Class ;
  rdfs:label "investigation agent role" ;
  rdfs:comment "A role borne by an entity and that is realized in a process that is part of an investigation in which an objective is achieved. These processes include, among others: planning, overseeing, funding, reviewing."@en ;
  rdfs:subClassOf obo:BFO_0000023 .

obo:IAO_0000701 a rdfs:Class ;
  rdfs:label "descriptive data section"@en ;
  rdfs:comment "A document part that lists and defines data variables, describes data characteristics (e.g. missing data information) and any assumptions and simplifications made."@en ;
  rdfs:subClassOf obo:IAO_0000314 .

obo:DUO_0000027 a rdfs:Class ;
  rdfs:label "project specific restriction"@en ;
  rdfs:comment "This data use modifier indicates that use is limited to use within an approved project."@en ;
  rdfs:subClassOf obo:DUO_0000017 .

obo:ICO_0000424 a rdfs:Class ;
  rdfs:label "covered entity role"@en ;
  rdfs:comment "A role based on the Health Insurance Portability and Accountability Act that inheres in individuals, organizations, and agencies that are also health care providers, health plans, or health care clearinghouse."@en ;
  rdfs:subClassOf obo:BFO_0000023 .

obo:IAO_0000613 a rdfs:Class ;
  rdfs:label "case report section"@en ;
  rdfs:comment "A part of a document about the medical history of a specific patient as it relates to the topic of the document."@en ;
  rdfs:subClassOf obo:IAO_0000314 .

obo:IAO_0000646 a rdfs:Class ;
  rdfs:label "postal code"@en ;
  rdfs:comment "An identifier that denotes some postal delivery route, some aggregate of postal delivery routes or a geographical region and was created for the purpose of sorting and delivering mail."@en ;
  rdfs:subClassOf obo:IAO_0020000 .

obo:IAO_0000322 a rdfs:Class ;
  rdfs:label "institution list"@en ;
  rdfs:comment "A part of a document that has parts that are institution identifications associated with the authors of the document"@en ;
  rdfs:subClassOf obo:IAO_0000314 .

obo:UBERON_0006314 a rdfs:Class ;
  rdfs:label "bodily fluid" ;
  rdfs:comment "Liquid components of living organisms. includes fluids that are excreted or secreted from the body as well as body water that normally is not." ;
  rdfs:subClassOf obo:UBERON_0000463 .

obo:IAO_8000019 a rdfs:Class ;
  rdfs:label "ontology module subsetted by OWL profile"@en ;
  rdfs:subClassOf obo:IAO_8000017 .

obo:OBI_0002610 a rdfs:Class ;
  rdfs:label "tongue swab specimen" ;
  rdfs:comment "A specimen that is collected with a swab from the surface of a tongue."@en ;
  rdfs:subClassOf obo:OBI_0002607 .

obo:ICO_0000008 a rdfs:Class ;
  rdfs:label "description of participation risk"@en ;
  rdfs:comment "A descriptive information content entity that describes potential harm or estimates the likelihood of harm."@en ;
  rdfs:subClassOf <http://www.ontologyrepository.com/CommonCoreOntologies/DescriptiveInformationContentEntity> .

obo:ICO_0000015 a rdfs:Class ;
  rdfs:label "signed informed consent form"@en ;
  rdfs:comment "An informed consent form that has been signed by at least one participant."@en .

obo:ICO_0000326 a rdfs:Class ;
  rdfs:label "designated object"@en ;
  rdfs:comment "A 'Designative Information Content Entity' that designates the object of a 'designated action'."@en ;
  rdfs:subClassOf <http://www.ontologyrepository.com/CommonCoreOntologies/DesignativeInformationContentEntity> .

obo:OBI_0002502 a rdfs:Class ;
  rdfs:label "cerebrospinal fluid specimen" ;
  rdfs:comment "A specimen that is derived from cerbrospinal fluid."@en ;
  rdfs:subClassOf obo:OBI_2000009 .

obo:OBI_0001010 a rdfs:Class ;
  rdfs:label "nucleic acid extract" ;
  rdfs:comment "An extract that is the output of an extraction process in which nucleic acid molecules are isolated from a specimen."@en ;
  rdfs:subClassOf obo:OBI_0000953 , obo:OBI_0100051 .

obo:IAO_0021017 a rdfs:Class ;
  rdfs:label "obsolete_claimant role"@en ;
  rdfs:comment "The role of a human being or an aggregate of human beings concretizing a claim."@en ;
  rdfs:subClassOf <http://www.geneontology.org/formats/oboInOwl#ObsoleteClass> .

obo:OBI_0002435 a rdfs:Class ;
  rdfs:label "exposure to blood borne infectious disease exclusion criterion" ;
  rdfs:comment "An exclusion criterion defined  as whether an individual has been exposed to a blood borne infections disease through needle sticks and/or contact with non-intact skin and/or contact with open wounds and/or contact with mucous membranes, which if met, makes the individual unsuitable for a given task or participation in a given process."@en ;
  rdfs:subClassOf obo:OBI_0500028 .

obo:OBI_0002779 a rdfs:Class ;
  rdfs:label "mid-turbinate nasal swab specimen" ;
  rdfs:comment "A specimen that is collected with a mid-turbinate nasal swab from the turbinate area of the nasal cavity."@en ;
  rdfs:subClassOf obo:OBI_0000917 .

obo:ICO_0000231 a rdfs:Class ;
  rdfs:label "jurisdiction"@en ;
  rdfs:comment "A site within which a deontic power may be realized, where that deontic power inheres in a formally created regulatory body."@en ;
  rdfs:subClassOf obo:BFO_0000029 .

obo:ICO_0000109 a rdfs:Class ;
  rdfs:label "act of canceling a permission"@en ;
  rdfs:comment "A planned process that revokes a permission role inhering in some agent."@en ;
  rdfs:subClassOf obo:OBI_0000011 .

obo:IAO_0000093 a rdfs:Class ;
  rdfs:label "obsolete2_binary executable"@en ;
  rdfs:comment "Binary executable is a digital entity consisting of the binary representation of machine instructions of a specific processor or they may be binary pseudocode for a virtual machine. A non-source executable file is also called an object program. It is assumed that the binary executable file contains properly-formatted computer instructions.  (derived from Wikipedia, Nov 1, 2007)"@en ;
  rdfs:subClassOf <http://www.geneontology.org/formats/oboInOwl#ObsoleteClass> .

obo:ICO_0000141 a rdfs:Class ;
  rdfs:label "question textual entity"@en ;
  rdfs:comment "A textual entity that is a sentence in the interrogative mood."@en ;
  rdfs:subClassOf obo:IAO_0000300 .

obo:OBI_0666666 a rdfs:Class ;
  rdfs:label "RNA extraction"@en ;
  rdfs:comment "A RNA extraction is a nucleic acid extraction where the desired output material is RNA"@en ;
  rdfs:subClassOf obo:OBI_0666667 .

obo:OMRSE_00000025 a rdfs:Class ;
  rdfs:label "organization social role"@en ;
  rdfs:comment "A role in human social processes that inheres in an organization."@en ;
  rdfs:subClassOf obo:OMRSE_00000024 .

obo:IAO_0000318 a rdfs:Class ;
  rdfs:label "results section"@en ;
  rdfs:comment "A part of a publication about an investigation that is about a study design execution"@en ;
  rdfs:subClassOf obo:IAO_0000314 .

obo:ICO_0000180 a rdfs:Class ;
  rdfs:label "obsolete process of providing broad consent for research with biological sample" ;
  rdfs:comment "A broad consent that is for an unspecified range of future research subject to a few content or process restrictions with biological sample."@en ;
  rdfs:subClassOf <http://www.geneontology.org/formats/oboInOwl#ObsoleteClass> .

obo:PATO_0000125 a rdfs:Class ;
  rdfs:label "mass" ;
  rdfs:comment "A physical quality that inheres in a bearer by virtue of the proportion of the bearer's amount of matter." ;
  rdfs:subClassOf obo:PATO_0001018 .

obo:ICO_0000253 a rdfs:Class ;
  rdfs:label "description of voluntary participation"@en ;
  rdfs:subClassOf <http://www.ontologyrepository.com/CommonCoreOntologies/DescriptiveInformationContentEntity> .

obo:ICO_0000127 a rdfs:Class ;
  rdfs:label "planned duration of study subject participation"@en ;
  rdfs:comment "A participation time that is the total length of time of subject's participation in a research study; from the time of enrollment to the completion of follow-up."@en ;
  rdfs:subClassOf obo:IAO_0000104 .

obo:ICO_0000146 a rdfs:Class ;
  rdfs:label "eligibility of candidate participation"@en ;
  rdfs:comment "A role that represents the eligibility of a candidate according to a study protocol."@en ;
  rdfs:subClassOf obo:BFO_0000023 .

obo:ICO_0000078 a rdfs:Class ;
  rdfs:label "risk"@en ;
  rdfs:comment "A risk is a disposition or the potential future harm that may arise from some present action. It is often combined or confused with the probability of an event which is seen as undesirable."@en ;
  rdfs:subClassOf obo:BFO_0000016 .

obo:IAO_0021006 a rdfs:Class ;
  rdfs:label "obligee role"@en ;
  rdfs:comment "A role that is either the specified output of an obligation generating social act or the concretization of a transferable obligation and that is realized by it's bearer being the providing part of a process that fulfills the previously agreed upon requirements."@en ;
  rdfs:subClassOf obo:BFO_0000023 .

obo:NCBITaxon_33213 a rdfs:Class ;
  rdfs:label "Bilateria" ;
  rdfs:subClassOf obo:NCBITaxon_33208 .

obo:DUO_0000028 a rdfs:Class ;
  rdfs:label "institution specific restriction"@en ;
  rdfs:comment "This data use modifier indicates that use is limited to use within an approved institution."@en ;
  rdfs:subClassOf obo:DUO_0000017 .

obo:IAO_8000015 a rdfs:Class ;
  rdfs:label "template generated ontology module"@en ;
  rdfs:comment "An ontology module that is automatically generated from a template specification and fillers for slots in that template."@en ;
  rdfs:seeAlso <http://robot.obolibrary.org/template> , <https://github.com/dosumis/dead_simple_owl_design_patterns/> , <https://doi.org/10.1186/s13326-017-0126-0> ;
  rdfs:subClassOf obo:IAO_8000014 .

obo:IAO_0000182 a rdfs:Class ;
  rdfs:label "obsolete_survival curve"@en ;
  rdfs:comment "A survival curve is a report graph which is a graphical representation of data where the percentage of survival is plotted as a function of time."@en ;
  rdfs:subClassOf <http://www.geneontology.org/formats/oboInOwl#ObsoleteClass> .

obo:PATO_0000146 a rdfs:Class ;
  rdfs:label "temperature" ;
  rdfs:comment "A physical quality of the thermal energy of a system." ;
  rdfs:subClassOf obo:PATO_0001018 .

obo:BFO_0000018 a rdfs:Class ;
  rdfs:label "zero-dimensional spatial region"@en ;
  rdfs:subClassOf obo:BFO_0000006 .

obo:OBI_0002517 a rdfs:Class ;
  rdfs:label "hair specimen" ;
  rdfs:comment "A specimen that is derived from hair."@en ;
  rdfs:subClassOf obo:OBI_0001479 .

obo:OBI_0002603 a rdfs:Class ;
  rdfs:label "areolar swab specimen" ;
  rdfs:comment "A specimen that is collected with a swab from the surface of an areola of a breast."@en ;
  rdfs:subClassOf obo:OBI_0002604 .

obo:IAO_0000300 a rdfs:Class ;
  rdfs:label "textual entity"@en ;
  rdfs:comment "A textual entity is a part of a manifestation (FRBR sense), a generically dependent continuant whose concretizations are patterns of glyphs intended to be interpreted as words, formulas, etc."@en ;
  rdfs:subClassOf obo:IAO_0000030 .

obo:BFO_0000003 a rdfs:Class ;
  rdfs:label "occurrent"@en ;
  rdfs:comment "An entity that has temporal parts and that happens, unfolds or develops through time."@en ;
  rdfs:subClassOf obo:BFO_0000001 .

obo:ICO_0000057 a rdfs:Class ;
  rdfs:label "for-profit research investigation"@en ;
  rdfs:comment "An investigation that is conducted with the purpose of earning a profit."@en ;
  rdfs:subClassOf obo:OBI_0000066 .

obo:IAO_0000595 a rdfs:Class ;
  rdfs:label "software script"@en ;
  rdfs:comment "A software script is software whose instructions can be executed using a software interpreter."@en ;
  rdfs:subClassOf obo:IAO_0000010 .

obo:ICO_0000246 a rdfs:Class ;
  rdfs:label "restriction directive"@en ;
  rdfs:comment "A directive information entity that prescribes actions that are impermissible."@en ;
  rdfs:subClassOf obo:IAO_0000033 .

obo:OBI_2000002 a rdfs:Class ;
  rdfs:label "cervical mucus specimen" ;
  rdfs:comment "A specimen that is derived from some cervical mucus"@en ;
  rdfs:subClassOf obo:OBI_0001479 , obo:OBI_2000009 .

obo:IAO_0000642 a rdfs:Class ;
  rdfs:label "requirements textual entity"@en ;
  rdfs:comment "A textual entity that expresses the requirements necessary to use a resource, e.g. software."@en ;
  rdfs:subClassOf obo:IAO_0000300 .

obo:ICO_0000040 a rdfs:Class ;
  rdfs:label "human subject consenter"@en ;
  rdfs:comment "A human subject who provides informed consent without a legal guardian."@en ;
  rdfs:subClassOf obo:NCBITaxon_9606 .

obo:UBERON_0000362 a rdfs:Class ;
  rdfs:label "renal medulla" ;
  rdfs:comment "The inner portion of the kidney consisting of the renal pyramids." ;
  rdfs:subClassOf obo:UBERON_0000481 .

obo:OGMS_0000045 a rdfs:Class ;
  rdfs:label "disorder" ;
  rdfs:comment "A material entity which is clinically abnormal and part of an extended organism. Disorders are the physical basis of disease."@en ;
  rdfs:subClassOf obo:BFO_0000040 .

obo:CHEBI_16991 a rdfs:Class ;
  rdfs:label "deoxyribonucleic acid" ;
  rdfs:comment "High molecular weight, linear polymers, composed of nucleotides containing deoxyribose and linked by phosphodiester bonds; DNA contain the genetic information of organisms." ;
  rdfs:subClassOf obo:CHEBI_33696 .

obo:UBERON_0007610 a rdfs:Class ;
  rdfs:label "tibial artery" ;
  rdfs:comment "The anterior and posterior arteries created at the bifurcation of the popliteal artery. The anterior tibial artery begins at the lower border of the popliteus muscle and lies along the tibia at the distal part of the leg to surface superficially anterior to the ankle joint. Its branches are distributed throughout the leg, ankle, and pes. The posterior tibial artery begins at the lower border of the popliteus muscle, lies behind the tibia in the lower part of its course, and is found situated between the medial malleolus and the medial process of the calcaneal tuberosity. Its branches are distributed throughout the leg and foot." ;
  rdfs:subClassOf obo:UBERON_0001637 .

obo:UBERON_0003688 a rdfs:Class ;
  rdfs:label "omentum" ;
  rdfs:comment "A fold of peritoneum originating at the stomach and supporting the viscera." ;
  rdfs:subClassOf obo:UBERON_0000465 .

obo:DUO_0000001 a rdfs:Class ;
  rdfs:label "data use permission"@en ;
  rdfs:comment "A data item that is used to indicate consent permissions for datasets and/or materials, and relates to the purposes for which datasets and/or material might be removed, stored or used."@en ;
  rdfs:subClassOf obo:IAO_0000027 .

obo:IAO_0000012 a rdfs:Class ;
  rdfs:label "obsolete2_digital entity"@en ;
  rdfs:comment "A digital entity is an information entity which is a collection of bits that can be interpreted by a computer. Two digital entities are the same if they are bitwise identical."@en ;
  rdfs:subClassOf <http://www.geneontology.org/formats/oboInOwl#ObsoleteClass> .

obo:IAO_0000408 a rdfs:Class ;
  rdfs:label "length measurement datum"@en ;
  rdfs:comment "A scalar measurement datum that is the result of measurement of length quality"@en ;
  rdfs:subClassOf obo:IAO_0000032 .

obo:IAO_0000590 a rdfs:Class ;
  rdfs:label "written name"@en ;
  rdfs:comment "A textual entity that denotes a particular in reality."@en ;
  rdfs:subClassOf obo:IAO_0000300 .

obo:OBI_0003666 a rdfs:Class ;
  rdfs:label "lavage fluid specimen" ;
  rdfs:comment "A specimen obtained through a lavage process which includes fluid in addition to cells and/or cellular secretions."@en ;
  rdfs:subClassOf obo:OBI_0000953 , obo:OBI_0001479 .

obo:DUO_0000038 a rdfs:Class ;
  rdfs:label "genetic research" ;
  rdfs:comment "Biomedical research concerning genetics (i.e., the study of genes, genetic variations and heredity)." ;
  rdfs:subClassOf obo:DUO_0000037 .

obo:OBI_0002784 a rdfs:Class ;
  rdfs:label "anterior nasal swab specimen" ;
  rdfs:comment "A specimen that is derived from the anterior nasal wall"@en ;
  rdfs:subClassOf obo:OBI_0000917 .

obo:OBI_2000005 a rdfs:Class ;
  rdfs:label "respiratory system specimen" ;
  rdfs:comment "A specimen that is derived from some respiratory system"@en ;
  rdfs:subClassOf obo:OBI_0001479 .

obo:IAO_0000065 a rdfs:Class ;
  rdfs:label "software interpreter"@en ;
  rdfs:comment "A software interpreter is a software application that executes some specified input software."@en ;
  rdfs:subClassOf obo:IAO_0000064 .

obo:ICO_0000179 a rdfs:Class ;
  rdfs:label "broad consent process"@en ;
  rdfs:comment "A planned process for an unspecified range of future research subject to a few content or process restrictions."@en ;
  rdfs:subClassOf obo:OBI_0000011 .

obo:UBERON_0001826 a rdfs:Class ;
  rdfs:label "nasal cavity mucosa" ;
  rdfs:comment "The mucous membrane that lines the nasal cavity[MP]." ;
  rdfs:subClassOf obo:UBERON_0000465 .

obo:IAO_0000057 a rdfs:Class ;
  rdfs:label "contour plot"@en ;
  rdfs:subClassOf obo:IAO_0000038 .

obo:ICO_0000051 a rdfs:Class ;
  rdfs:label "cancer research investigation"@en ;
  rdfs:comment "An investigation that targets cancer research."@en ;
  rdfs:subClassOf obo:OBI_0000066 .

obo:DUO_0000016 a rdfs:Class ;
  rdfs:label "genetic studies only"@en ;
  rdfs:comment "This data use modifier indicates that use is limited to genetic studies only (i.e., studies that include genotype research alone or both genotype and phenotype research, but not phenotype research exclusively)"@en ;
  rdfs:subClassOf obo:DUO_0000017 .

obo:OBI_0003667 a rdfs:Class ;
  rdfs:label "oral lavage fluid" ;
  rdfs:comment "A specimen collected through oral cavity lavage that contains the reagents used to for the lavage process, organisms, cells, cellular secretions, and other biomaterials present in the oral cavity space."@en ;
  rdfs:subClassOf obo:OBI_0003666 .

obo:OBI_0500026 a rdfs:Class ;
  rdfs:label "eligibility criterion"@en ;
  rdfs:comment """an eligibility criterion (rule) is_a selection criterion which 
defines and states the requirements (positive or negative) for an entity to be considered as suitable for a given task or participation in a process."""@en ;
  rdfs:subClassOf obo:IAO_0000033 .

obo:CHEBI_33697 a rdfs:Class ;
  rdfs:label "ribonucleic acid" ;
  rdfs:comment "High molecular weight, linear polymers, composed of nucleotides containing ribose and linked by phosphodiester bonds; RNA is central to the synthesis of proteins." ;
  rdfs:subClassOf obo:CHEBI_33696 .

obo:ICO_0000019 a rdfs:Class ;
  rdfs:label "signature section"@en ;
  rdfs:comment "A document part that is specified as a place to receive a signature."@en ;
  rdfs:subClassOf obo:IAO_0000314 .

obo:IAO_0000620 a rdfs:Class ;
  rdfs:label "ethical approval section"@en ;
  rdfs:comment "A part of a document about the governance body responsible for approving the work discussed in a document on an ethical basis."@en ;
  rdfs:subClassOf obo:IAO_0000314 .

obo:UO_0000002 a rdfs:Class ;
  rdfs:label "mass unit" ;
  rdfs:comment "A unit which is a standard measure of the amount of matter/energy of a physical object." ;
  rdfs:subClassOf obo:IAO_0000003 .

obo:ICO_0000035 a rdfs:Class ;
  rdfs:label "date specification in informed consent form"@en ;
  rdfs:comment "A data item that indicates a date that specified on an informed consent form."@en ;
  rdfs:subClassOf obo:IAO_0000027 .

obo:UBERON_0000316 a rdfs:Class ;
  rdfs:label "cervical mucus" ;
  rdfs:comment "A substance produced by the cervix and endocervical glands[BTO]. Thick acidic mucus that blocks the cervical os after mestruation[WP]. This 'infertile' mucus blocks spermatozoa from entering the uterus." ;
  rdfs:subClassOf obo:UBERON_0006314 .

obo:OBI_0000372 a rdfs:Class ;
  rdfs:label "material separation function"@en ;
  rdfs:comment "A material separation function is a function that increases the resolution between two or more material entities. The  to distinction between the entities is usually based on some associated physical quality."@en ;
  rdfs:subClassOf obo:BFO_0000034 .

obo:IAO_0000307 a rdfs:Class ;
  rdfs:label "table of abbreviations"@en ;
  rdfs:comment "A table where the constituent texts are abbreviations and their expansions"@en ;
  rdfs:subClassOf obo:IAO_0000306 .

obo:OBI_0002785 a rdfs:Class ;
  rdfs:label "aspiration specimen collection"@en ;
  rdfs:comment "Procedure using suction, usually with a thin needle and syringe, to remove bodily fluid or tissue."@en ;
  rdfs:subClassOf obo:OBI_0000659 .

obo:ICO_0000076 a rdfs:Class ;
  rdfs:label "obsolete authorization for medical records release" ;
  rdfs:comment "An authorization process aims to release the medical record."@en ;
  rdfs:subClassOf <http://www.geneontology.org/formats/oboInOwl#ObsoleteClass> .

obo:IAO_0000128 a rdfs:Class ;
  rdfs:label "obsolete_identifier" ;
  rdfs:subClassOf <http://www.geneontology.org/formats/oboInOwl#ObsoleteClass> .

obo:OBI_0100051 a rdfs:Class ;
  rdfs:label "specimen"@en ;
  rdfs:comment "A material entity that is collected for potential use as an input upon which measurements or observations are performed."@en ;
  rdfs:subClassOf obo:BFO_0000040 .

obo:OBI_0000899 a rdfs:Class ;
  rdfs:label "organellar RNA extract" ;
  rdfs:comment "A RNA extract that is the output of an extraction process in which RNA molecules found in an organelle, e.g., mitochondrion, ER, or chloroplast, excluding the nucleus, are extracted."@en ;
  rdfs:subClassOf obo:OBI_0000880 .

obo:IAO_0000097 a rdfs:Class ;
  rdfs:label "obsolete_report table"@en ;
  rdfs:comment "A report table is a report display element consisting of a matrix of cells layed out in a grid, some set of which are filled with some information content"@en ;
  rdfs:subClassOf <http://www.geneontology.org/formats/oboInOwl#ObsoleteClass> .

obo:ICO_0000065 a rdfs:Class ;
  rdfs:label "clinical trial"@en ;
  rdfs:comment "A study that is a clinical trial that requires an informed consent process."@en ;
  rdfs:subClassOf obo:OBI_0000066 .

obo:IAO_0021021 a rdfs:Class ;
  rdfs:label "document act template creator role"@en ;
  rdfs:comment "A role that inheres in a human being or organization or aggregate of any of the aforementioned that prepares a document that is the specified input to a document act and is the input document of a document act."@en ;
  rdfs:subClassOf obo:BFO_0000023 .

obo:ICO_0000046 a rdfs:Class ;
  rdfs:label "act of authorizing"@en ;
  rdfs:comment "A planned process of making the decision of the competent authorities in form of a letter, document, or verbal or electronic form, that confirms that somebody has permission to do something or be somewhere, e.g. to realize a given project."@en ;
  rdfs:subClassOf obo:IAO_0021003 .

obo:BFO_0000140 a rdfs:Class ;
  rdfs:label "continuant fiat boundary"@en ;
  rdfs:comment "b is a continuant fiat boundary = Def. b is an immaterial entity that is of zero, one or two dimensions and does not include a spatial region as part. (axiom label in BFO2 Reference: [029-001])"@en ;
  rdfs:subClassOf obo:BFO_0000141 .

obo:OGMS_0000056 a rdfs:Class ;
  rdfs:label "clinical laboratory test" ;
  rdfs:comment "A measurement assay that has as input a patient-derived specimen and as output a data item that is about a quality of the specimen."@en ;
  rdfs:subClassOf obo:OBI_0000011 .

obo:ICO_0000275 a rdfs:Class ;
  rdfs:label "description of discomfort"@en ;
  rdfs:comment "A descriptive information content entity that describes an emotional state of mental or physical uneasiness."@en ;
  rdfs:subClassOf <http://www.ontologyrepository.com/CommonCoreOntologies/DescriptiveInformationContentEntity> .

obo:ICO_0000234 a rdfs:Class ;
  rdfs:label "human subject research regulatory document"@en ;
  rdfs:comment "A regulatory document designed to prescribe research involving human subjects."@en ;
  rdfs:subClassOf obo:ICO_0000233 .

obo:UBERON_0001087 a rdfs:Class ;
  rdfs:label "pleural fluid" ;
  rdfs:comment "Transudate contained in the pleural cavity." ;
  rdfs:subClassOf obo:UBERON_0006314 .

obo:DUO_0000020 a rdfs:Class ;
  rdfs:label "collaboration required"@en ;
  rdfs:comment "This data use modifier indicates that the requestor must agree to collaboration with the primary study investigator(s)."@en ;
  rdfs:subClassOf obo:DUO_0000017 .

obo:OBI_0000456 a rdfs:Class ;
  rdfs:label "material transformation objective"@en ;
  rdfs:comment "an objective specifiction that creates an specific output object from input materials."@en ;
  rdfs:subClassOf obo:IAO_0000005 .

obo:OBI_0002532 a rdfs:Class ;
  rdfs:label "esophagus mucosa specimen" ;
  rdfs:comment "A specimen that is derived from esophagus mucosa."@en ;
  rdfs:subClassOf obo:OBI_0003483 .

obo:OBI_0002563 a rdfs:Class ;
  rdfs:label "ethnicity inclusion criterion"@en ;
  rdfs:comment "An inclusion criteria that defines and states one or more ethnicities which, if met, makes an entity suitable for a given task or participation in a given process."@en ;
  rdfs:subClassOf obo:OBI_0500027 .

obo:ICO_0000289 a rdfs:Class ;
  rdfs:label "prisoner role"@en ;
  rdfs:comment "A role inhering in a Homo sapiens that is realized in a process of incarceration."@en ;
  rdfs:subClassOf obo:BFO_0000023 .

obo:APOLLO_SV_00000522 a rdfs:Class ;
  rdfs:label "source code repository"@en ;
  rdfs:comment "A document that comprises at least one source code module and provenance data about who contributed the set of files making up the module(s), and optionally comprises also multiple versions of files with detailed change history about who committed files and when, a license for the software, readme files, documentation, executables, etc."@en ;
  rdfs:subClassOf obo:IAO_0000310 .

obo:IAO_0000627 a rdfs:Class ;
  rdfs:label "genome announcement section"@en ;
  rdfs:comment "A document part announcing the publication of a novel draft genome sequence."@en ;
  rdfs:subClassOf obo:IAO_0000314 .

obo:OBI_0600005 a rdfs:Class ;
  rdfs:label "collecting specimen from organism"@en ;
  rdfs:comment "a process with the objective to obtain a material entity that was part of an organism for potential future use in an investigation"@en ;
  rdfs:subClassOf obo:OBI_0000659 .

obo:OBI_0002547 a rdfs:Class ;
  rdfs:label "minor salivary gland specimen" ;
  rdfs:comment "A specimen that is derived from minor salivary gland."@en ;
  rdfs:subClassOf obo:OBI_0001479 .

obo:OOSTT_00000117 a rdfs:Class ;
  rdfs:label "committee member role"@en ;
  rdfs:comment "A role that, if realized, is realized in the organizational context of a committee."@en ;
  rdfs:subClassOf obo:BFO_0000023 .

obo:ICO_0000357 a rdfs:Class ;
  rdfs:label "permission restriction directive"@en ;
  rdfs:comment "A 'permission requirement directive' that directs a 'permissable' limit of a 'consent directive'."@en ;
  rdfs:subClassOf obo:ICO_0000327 .

obo:IAO_0000702 a rdfs:Class ;
  rdfs:label "additional results section"@en ;
  rdfs:comment "A results section that reports analyses other than main results of the study (e.g. subgroups analyses, adjusted analyses, sensitivity analyses, etc.)"@en ;
  rdfs:subClassOf obo:IAO_0000318 .

obo:OBI_0003380 a rdfs:Class ;
  rdfs:label "placental blood specimen" ;
  rdfs:comment "A specimen that is derived from placental blood."@en ;
  rdfs:subClassOf obo:OBI_0000655 .

obo:OBI_0002124 a rdfs:Class ;
  rdfs:label "H&E slide staining"@en ;
  rdfs:comment "A staining using hematoxylin and eosin. The staining is applied to fixed specimens on slides to observe the whole structure and morphology of cells in a tissue; nuclei are stained dark blue/purple while cytoplasm is stained pink."@en ;
  rdfs:subClassOf obo:OBI_0302887 .

obo:ICO_0000349 a rdfs:Class ;
  rdfs:label "designated educational purpose"@en ;
  rdfs:comment "A 'permission purpose directive'  that designates an educational process as its end."@en ;
  rdfs:subClassOf obo:ICO_0000328 .

obo:ICO_0000152 a rdfs:Class ;
  rdfs:label "obsolete eligibility screening person" ;
  rdfs:subClassOf <http://www.geneontology.org/formats/oboInOwl#ObsoleteClass> .

obo:ICO_0000223 a rdfs:Class ;
  rdfs:label "consent power role"@en ;
  rdfs:comment "A deontic power role that may be realized in an act of consent that is a process part of an informed consent process."@en ;
  rdfs:subClassOf obo:ICO_0000215 .

obo:UBERON_0001836 a rdfs:Class ;
  rdfs:label "saliva" ;
  rdfs:comment "A fluid produced in the oral cavity by salivary glands, typically used in predigestion, but also in other functions." ;
  rdfs:subClassOf obo:UBERON_0000463 .

obo:ICO_0000264 a rdfs:Class ;
  rdfs:label "educational vulnerability"@en ;
  rdfs:comment "A vulnerability due to exposure to a harsh learning environment."@en ;
  rdfs:subClassOf <http://purl.unep.org/sdg/SDGIO_00000024> .

obo:BFO_0000031 a rdfs:Class ;
  rdfs:label "generically dependent continuant"@en ;
  rdfs:comment "A continuant that is dependent on one or other independent continuant bearers. For every instance of A requires some instance of (an independent continuant type) B but which instance of B serves can change from time to time."@en ;
  rdfs:subClassOf obo:BFO_0000002 .

obo:IAO_8000020 a rdfs:Class ;
  rdfs:label "EL++ ontology module"@en ;
  rdfs:subClassOf obo:IAO_8000019 .

obo:IAO_0000635 a rdfs:Class ;
  rdfs:label "patients section"@en ;
  rdfs:comment "A part of a document about the patients that participated in a study."@en ;
  rdfs:subClassOf obo:IAO_0000314 .

obo:OBI_0002780 a rdfs:Class ;
  rdfs:label "nasal aspirate specimen" ;
  rdfs:comment "A specimen that is collected with a suctioning tube from the nasal cavity."@en ;
  rdfs:subClassOf obo:OBI_2000006 .

obo:IAO_0000140 a rdfs:Class ;
  rdfs:label "setting datum"@en ;
  rdfs:comment "A settings datum is a datum that denotes some configuration of an instrument."@en ;
  rdfs:subClassOf obo:IAO_0000027 .

obo:OBI_0000257 a rdfs:Class ;
  rdfs:label "DNA extraction"@en ;
  rdfs:comment "A DNA extraction is a nucleic acid extraction where the desired output material is DNA."@en ;
  rdfs:subClassOf obo:OBI_0666667 .

obo:ICO_0000135 a rdfs:Class ;
  rdfs:label "explaining record confidentiality to participant candidate"@en ;
  rdfs:comment "In order to enable the candidate to make voluntary decision, the options for enhancing the protection of confidentiality for participants who have contributed personal information to a study is to be explained."@en ;
  rdfs:subClassOf obo:ICO_0000154 .

obo:ICO_0000413 a rdfs:Class ;
  rdfs:label "designated gender research purpose"@en ;
  rdfs:comment "A 'designated biomedical research purpose' that designates a process of gender category research as its end."@en ;
  rdfs:subClassOf obo:ICO_0000345 .

obo:OBI_0000652 a rdfs:Class ;
  rdfs:label "material combination" ;
  rdfs:comment "is a material processing with the objective to combine two or more material entities as input into a single material entity as output."@en ;
  rdfs:subClassOf obo:OBI_0000094 .

obo:NCIT_C85521 a rdfs:Class ;
  rdfs:label "Incarceration" ;
  rdfs:comment "The state of being confined to jail or prison." ;
  rdfs:subClassOf obo:BFO_0000015 .

obo:ICO_0000037 a rdfs:Class ;
  rdfs:label "project duration specification" ;
  rdfs:comment "A temporal region identifier that designates a project duration."@en ;
  rdfs:subClassOf obo:ICO_0000022 .

obo:OBI_0002542 a rdfs:Class ;
  rdfs:label "aorta specimen" ;
  rdfs:comment "A specimen that is derived from aorta."@en ;
  rdfs:subClassOf obo:OBI_0001479 .

obo:ICO_0000082 a rdfs:Class ;
  rdfs:label "obsolete legal guardian" ;
  rdfs:subClassOf <http://www.geneontology.org/formats/oboInOwl#ObsoleteClass> .

obo:ICO_0000203 a rdfs:Class ;
  rdfs:label "obsolete assenter role" ;
  rdfs:comment "A role that is the output of an act of assent and which inheres in a human being, who, because they fail to satisfy certain criteria for consent, is thereby allowed the aid of a legal representative who aids them in an Act of Consent, and, in some contexts, may be realized in revoking or modifying the permission role that was output of the informed consent process of which the the Act of Assent was a process part."@en ;
  rdfs:subClassOf <http://www.geneontology.org/formats/oboInOwl#ObsoleteClass> .

obo:UBERON_0006911 a rdfs:Class ;
  rdfs:label "digestive system secreted substance" ;
  rdfs:subClassOf obo:UBERON_0000463 .

obo:OBI_0000319 a rdfs:Class ;
  rdfs:label "material to be added role"@en ;
  rdfs:comment "A role of a material entity that is realized in an \"adding a material entity into a target\" process where the bearer of the role is added into another material entity (the target)."@en ;
  rdfs:subClassOf obo:BFO_0000023 .

obo:DUO_00000044 a rdfs:Class ;
  rdfs:label "population origins or ancestry research prohibited"@en ;
  rdfs:comment "This data use modifier indicates use for purposes of population, origin, or ancestry research is prohibited."@en ;
  rdfs:subClassOf obo:DUO_0000017 .

obo:DUO_0000042 a rdfs:Class ;
  rdfs:label "general research use"@en ;
  rdfs:comment "This data use permission indicates that use is allowed for general research use for any research purpose."@en ;
  rdfs:subClassOf obo:DUO_0000001 .

obo:OBI_0000888 a rdfs:Class ;
  rdfs:label "nuclear RNA extraction" ;
  rdfs:comment "A RNA extraction process in which the desired output material is RNA in the nucleus."@en ;
  rdfs:subClassOf obo:OBI_0666666 .

obo:UBERON_0001555 a rdfs:Class ;
  rdfs:label "digestive tract" ;
  rdfs:comment "A tube extending from the mouth to the anus." ;
  rdfs:subClassOf obo:UBERON_0000465 .

obo:ICO_0000346 a rdfs:Class ;
  rdfs:label "designated genetic research purpose"@en ;
  rdfs:comment "A 'designated research purpose' that designates a process of genetic research as its end."@en ;
  rdfs:subClassOf obo:ICO_0000345 .

obo:OBI_0002778 a rdfs:Class ;
  rdfs:label "tracheal aspirate specimen" ;
  rdfs:comment "A specimen that is collected with a suctioning tube from the trachea."@en ;
  rdfs:subClassOf obo:OBI_0002781 , obo:OBI_0002783 .

obo:UBERON_0002037 a rdfs:Class ;
  rdfs:label "cerebellum" ;
  rdfs:comment "Part of the metencephalon that lies in the posterior cranial fossa behind the brain stem. It is concerned with the coordination of movement[MESH]. A large dorsally projecting part of the brain concerned especially with the coordination of muscles and the maintenance of bodily equilibrium, situated between the brain stem and the back of the cerebrum , and formed in humans of two lateral lobes and a median lobe[BTO]. Brain structure derived from the anterior hindbrain, and perhaps including posterior midbrain. The cerebellum plays a role in somatic motor function, the control of muscle tone, and balance[ZFA]." ;
  rdfs:subClassOf obo:UBERON_0000481 .

obo:IAO_0000594 a rdfs:Class ;
  rdfs:label "software application"@en ;
  rdfs:comment "A software application is software that can be directly executed by some processing unit."@en ;
  rdfs:subClassOf obo:IAO_0000010 .

obo:DUO_0000005 a rdfs:Class ;
  rdfs:label "obsolete general research use and clinical care"@en ;
  rdfs:comment "This data use limitation indicates that use is allowed for health/medical/biomedical purposes and other biological research, including the study of population origins or ancestry."@en ;
  rdfs:subClassOf <http://www.geneontology.org/formats/oboInOwl#ObsoleteClass> .

obo:IAO_0000304 a rdfs:Class ;
  rdfs:label "caption"@en ;
  rdfs:comment "A textual entity that describes a figure"@en ;
  rdfs:subClassOf obo:IAO_0000300 .

obo:ICO_0000174 a rdfs:Class ;
  rdfs:label "filling informed consent form"@en ;
  rdfs:comment "A planned process that involves the filling of an informed consent form."@en ;
  rdfs:subClassOf obo:OBI_0000011 .

obo:IAO_0000005 a rdfs:Class ;
  rdfs:label "objective specification"@en ;
  rdfs:comment "A directive information entity that describes an intended process endpoint. When part of a plan specification the concretization is realized in a planned process in which the bearer tries to effect the world so that the process endpoint is achieved."@en ;
  rdfs:subClassOf obo:IAO_0000033 .

obo:ICO_0000280 a rdfs:Class ;
  rdfs:label "contact method directive"@en ;
  rdfs:comment "A directive information entity that prescribes methods for contacting an agent."@en ;
  rdfs:subClassOf obo:IAO_0000033 .

obo:ICO_0000113 a rdfs:Class ;
  rdfs:label "anonymized information content entity"@en ;
  rdfs:comment "An information content entity that has been processed to prevent the identification of the person with whom the data are associated, thereby enduring in a stasis of anonymization."@en ;
  rdfs:subClassOf obo:IAO_0000030 .

obo:ICO_0000271 a rdfs:Class ;
  rdfs:label "obsolete risk" ;
  rdfs:subClassOf <http://www.geneontology.org/formats/oboInOwl#ObsoleteClass> .

obo:IAO_0021009 a rdfs:Class ;
  rdfs:label "deontic declaration"@en ;
  rdfs:comment "A social act that creates or revokes a deontic role." ;
  rdfs:subClassOf obo:IAO_0021003 .

obo:IAO_0000445 a rdfs:Class ;
  rdfs:label "document in preparation for publication"@en ;
  rdfs:comment "A document that is in preparation for submission to be published."@en ;
  rdfs:subClassOf obo:IAO_0000310 .

obo:ICO_0000016 a rdfs:Class ;
  rdfs:label "allowed research scope in informed consent form"@en ;
  rdfs:comment "A directive information entity that specifies the scope of allowed research and is derived from a research protocol."@en ;
  rdfs:subClassOf obo:IAO_0000033 .

obo:ICO_0000245 a rdfs:Class ;
  rdfs:label "obsolete conditional permission directive" ;
  rdfs:comment "A conditional specification that prescirbes a permission, should some trigger condition obtain."@en ;
  rdfs:subClassOf <http://www.geneontology.org/formats/oboInOwl#ObsoleteClass> .

obo:IAO_0000579 a rdfs:Class ;
  rdfs:label "centrally registered identifier registry"@en ;
  rdfs:comment "A CRID registry is a dataset of CRID records, each consisting of a CRID symbol and additional information which was recorded in the dataset through a assigning a centrally registered identifier process."@en ;
  rdfs:subClassOf obo:IAO_0000100 .

obo:UBERON_0001052 a rdfs:Class ;
  rdfs:label "rectum" ;
  rdfs:comment "The terminal portion of the intestinal tube, terminating with the anus." ;
  rdfs:subClassOf obo:UBERON_0000465 .

obo:ICO_0000258 a rdfs:Class ;
  rdfs:label "consent language directive"@en ;
  rdfs:comment "A directive information entity that prescribes the language that must be used in an informed consent process."@en ;
  rdfs:subClassOf obo:IAO_0000033 .

obo:UBERON_0000341 a rdfs:Class ;
  rdfs:label "throat" ;
  rdfs:comment "In anatomy, the throat is the anterior part of the neck, in front of the vertebral column. It consists of the pharynx and larynx. An important feature of the throat is the epiglottis, a flap which separates the esophagus from the trachea and prevents inhalation of food or drink. The throat contains various blood vessels, various pharyngeal muscles, the trachea (windpipe) and the esophagus. The hyoid bone and the clavicle are the only bones located in the throat of mammals. It is sometimes considered a synonym for fauces. [WP,unvetted]." ;
  rdfs:subClassOf obo:UBERON_0000465 .

obo:ICO_0000239 a rdfs:Class ;
  rdfs:label "disclosure directive"@en ;
  rdfs:comment "A directive information entity that prescribes information that must be revealed and prescribes to whom that information must be revealed."@en ;
  rdfs:subClassOf obo:IAO_0000033 .

<https://w3id.org/linkml/Any> a rdfs:Class ;
  rdfs:comment "An unconstrained type or object" .

obo:OBI_0000862 a rdfs:Class ;
  rdfs:label "nuclear RNA extract" ;
  rdfs:comment "A RNA extract that is the output of an extraction process in which RNA molecules found in the nucleus, including mRNA precursors (pre-mRNA), are extracted."@en ;
  rdfs:subClassOf obo:OBI_0000880 .

obo:OBI_2000017 a rdfs:Class ;
  rdfs:label "reticulocyte specimen" ;
  rdfs:comment "A specimen that is derived from some reticulocytes"@en ;
  rdfs:subClassOf obo:OBI_0001468 .

obo:IAO_0000315 a rdfs:Class ;
  rdfs:label "abstract"@en ;
  rdfs:comment "A summary of the entire document that is substantially smaller than the document it summarizes.  It is about the document it summarizes."@en ;
  rdfs:subClassOf obo:IAO_0000314 .

obo:OBI_0200000 a rdfs:Class ;
  rdfs:label "data transformation"@en ;
  rdfs:comment "A planned process that produces output data from input data."@en ;
  rdfs:subClassOf obo:OBI_0000011 .

obo:IAO_0000639 a rdfs:Class ;
  rdfs:label "related work section"@en ;
  rdfs:comment "A part of a document about work in other publications that is relevant to the content of the document."@en ;
  rdfs:subClassOf obo:IAO_0000314 .

obo:IAO_8000008 a rdfs:Class ;
  rdfs:label "analysis subset ontology module"@en ;
  rdfs:comment "An ontology module that is intended for usage in analysis or discovery applications."@en ;
  rdfs:subClassOf obo:IAO_8000006 .

obo:UBERON_0002369 a rdfs:Class ;
  rdfs:label "adrenal gland" ;
  rdfs:comment "Either of a pair of complex endocrine organs near the anterior medial border of the kidney consisting of a mesodermal cortex that produces glucocorticoid, mineralocorticoid, and androgenic hormones and an ectodermal medulla that produces epinephrine and norepinephrine[BTO]." ;
  rdfs:subClassOf obo:UBERON_0000465 .

obo:BFO_0000147 a rdfs:Class ;
  rdfs:label "zero-dimensional continuant fiat boundary"@en ;
  rdfs:subClassOf obo:BFO_0000140 .

obo:ICO_0000309 a rdfs:Class ;
  rdfs:label "abused person role"@en ;
  rdfs:comment "A role inhering in a Homo sapiens that, if realized, is realized in being a passive participant in some act of abuse process."@en ;
  rdfs:subClassOf obo:BFO_0000023 .

obo:OBI_0002744 a rdfs:Class ;
  rdfs:label "molecular label"@en ;
  rdfs:comment "A molecular reagent intended to associate with some molecular target to serve as a proxy for the presence, abundance, or location of this target in a detection of molecular label assay"@en ;
  rdfs:subClassOf obo:CHEBI_23367 , obo:OBI_0001879 .

obo:ICO_0000282 a rdfs:Class ;
  rdfs:label "description of legal responsibility"@en ;
  rdfs:comment "A descriptive information content entity that describes legal responsibility that an entity has due to some risk."@en ;
  rdfs:subClassOf <http://www.ontologyrepository.com/CommonCoreOntologies/DescriptiveInformationContentEntity> .

obo:ICO_0000048 a rdfs:Class ;
  rdfs:label "nonprofit organization"@en ;
  rdfs:comment "An organization that is operated without the principal goal of making a financial profit."@en ;
  rdfs:subClassOf obo:OBI_0000245 .

obo:UBERON_0005921 a rdfs:Class ;
  rdfs:label "middle nasal concha" ;
  rdfs:comment "The medial surface of the labyrinth of ethmoid consists of a thin lamella, which descends from the under surface of the cribriform plate, and ends below in a free, convoluted margin, the middle nasal concha. It is rough, and marked above by numerous grooves, directed nearly vertically downward from the cribriform plate; they lodge branches of the olfactory nerves, which are distributed to the mucous membrane covering the superior nasal concha." ;
  rdfs:subClassOf obo:UBERON_0000465 .

obo:OBI_0100066 a rdfs:Class ;
  rdfs:label "organ section"@en ;
  rdfs:comment "A processed material which derives from an organ and results from a process of dissection or histological sample preparation a portion(formerly an organ section is portion of an organ removed from the context of the organ)"@en ;
  rdfs:subClassOf obo:OBI_0000047 .

obo:ICO_0000370 a rdfs:Class ;
  rdfs:label "designated health information"@en ;
  rdfs:comment "A 'designated data' that designates data about health."@en ;
  rdfs:subClassOf obo:ICO_0000367 .

obo:OBI_0000659 a rdfs:Class ;
  rdfs:label "specimen collection process" ;
  rdfs:comment "A planned process with the objective to obtain a material entity for potential use as an input upon which measurements or observations are performed."@en ;
  rdfs:subClassOf obo:OBI_0000011 .

<http://www.ontologyrepository.com/CommonCoreOntologies/Government> a rdfs:Class ;
  rdfs:label "government"@en ;
  rdfs:comment "An Organization that exercises executive, legislative, or judicial authority over a Geopolitical Entity."@en ;
  rdfs:subClassOf obo:OBI_0000245 .

obo:BFO_0000144 a rdfs:Class ;
  rdfs:label "process profile"@en ;
  rdfs:comment "b is a process_profile =Def. there is some process c such that b process_profile_of c (axiom label in BFO2 Reference: [093-002])"@en ;
  rdfs:subClassOf obo:BFO_0000015 .

obo:OBI_0001472 a rdfs:Class ;
  rdfs:label "specimen with known storage state" ;
  rdfs:comment "A specimen for which it is known whether it has been subjected to storage of a specified type."@en ;
  rdfs:subClassOf obo:OBI_0100051 .

obo:ICO_0000278 a rdfs:Class ;
  rdfs:label "description of future biospecimen use"@en ;
  rdfs:comment "A descriptive information content entity that describes how biospecimens will be used."@en ;
  rdfs:subClassOf obo:ICO_0000305 .

obo:OBI_0002536 a rdfs:Class ;
  rdfs:label "cerebral cortex specimen" ;
  rdfs:comment "A specimen that is derived from cerebral cortex."@en ;
  rdfs:subClassOf obo:OBI_0002516 .

obo:IAO_0020000 a rdfs:Class ;
  rdfs:label "identifier"@en ;
  rdfs:comment "An identifier is an information content entity that is the outcome of a dubbing process and is used to refer to one instance of entity shared by a group of people to refer to that individual entity."@en ;
  rdfs:subClassOf obo:IAO_0000030 .

obo:OBI_0000902 a rdfs:Class ;
  rdfs:label "post mortem specimen" ;
  rdfs:comment "a specimen that was taken from a dead organism"@en ;
  rdfs:subClassOf obo:OBI_0001506 .

obo:ICO_0000149 a rdfs:Class ;
  rdfs:label "act of contact for future research"@en ;
  rdfs:comment "A planned process in which an agent contacts a participant of an informed consent process regarding opportunities related to future research."@en ;
  rdfs:subClassOf obo:OBI_0000011 .

obo:ICO_0000228 a rdfs:Class ;
  rdfs:label "act of data sharing"@en ;
  rdfs:comment "A planned process in which data possessed by one person or organization is shared with one or more other persons or organizations."@en ;
  rdfs:subClassOf obo:OBI_0000011 .

obo:ICO_0000320 a rdfs:Class ;
  rdfs:label "legally authorized representative role directive"@en ;
  rdfs:comment "A role directive that prescribes the bearer of a legally authorized representative role in process."@en ;
  rdfs:subClassOf obo:ICO_0000316 .

obo:ICO_0000188 a rdfs:Class ;
  rdfs:label "organization-specified contact role"@en ;
  rdfs:comment "A role borne by a human being who is part of a group of individuals and acts as a contact person for the group."@en ;
  rdfs:subClassOf obo:ICO_0000230 .

obo:BFO_0000024 a rdfs:Class ;
  rdfs:label "fiat object part"@en ;
  rdfs:subClassOf obo:BFO_0000040 .

obo:ICO_0000396 a rdfs:Class ;
  rdfs:label "designated team"@en ;
  rdfs:comment "A 'designated actor' that designates a team."@en ;
  rdfs:subClassOf obo:ICO_0000325 .

obo:GAZ_00000448 a rdfs:Class ;
  rdfs:label "geographic location" ;
  rdfs:comment "A reference to a place on the Earth, by its name or by its geographical location." ;
  rdfs:subClassOf obo:BFO_0000029 .

obo:NCBITaxon_32524 a rdfs:Class ;
  rdfs:label "Amniota" ;
  rdfs:subClassOf obo:NCBITaxon_32523 .

obo:ICO_0000087 a rdfs:Class ;
  rdfs:label "study duration measurement"@en ;
  rdfs:comment "A time measurement datum that measures the duration of a study."@en ;
  rdfs:subClassOf obo:IAO_0000109 .

obo:OBI_0001225 a rdfs:Class ;
  rdfs:label "genetic population background information"@en ;
  rdfs:comment "a genetic characteristics information which is a part of genotype information that identifies the population of organisms"@en ;
  rdfs:subClassOf obo:OBI_0001404 .

obo:OBI_0000873 a rdfs:Class ;
  rdfs:label "pre-mortem specimen" ;
  rdfs:comment "a specimen that was taken from a live organism"@en ;
  rdfs:subClassOf obo:OBI_0001506 .

obo:ICO_0000293 a rdfs:Class ;
  rdfs:label "data sharing directive"@en ;
  rdfs:comment "A directive information entity that prescribes the information that is permitted to be shared or the processes for sharing that information."@en ;
  rdfs:subClassOf obo:IAO_0000033 .

obo:ICO_0000024 a rdfs:Class ;
  rdfs:label "partially filled informed consent form"@en ;
  rdfs:comment "An informed consent form that has been partially filled with required contents."@en .

<http://www.ontologyrepository.com/CommonCoreOntologies/DescriptiveInformationContentEntity> a rdfs:Class ;
  rdfs:label "descriptive information content entity"@en ;
  rdfs:comment "An information content entity that consists of a set of propositions that describe some entity."@en ;
  rdfs:subClassOf obo:IAO_0000030 .

obo:IAO_0000179 a rdfs:Class ;
  rdfs:label "histogram"@en ;
  rdfs:comment """A histogram is a report graph which is a statistical description of a
distribution in terms of occurrence frequencies of different event classes."""@en ;
  rdfs:subClassOf obo:IAO_0000038 .

obo:IAO_0000328 a rdfs:Class ;
  rdfs:label "table of figures"@en ;
  rdfs:comment "A table that relates figures in a document to specific locations in that document (usually page numbers).  This is also a document part (subsumption there should be inferred)."@en ;
  rdfs:subClassOf obo:IAO_0000306 .

obo:IAO_0000616 a rdfs:Class ;
  rdfs:label "conflict of interest section"@en ;
  rdfs:comment "A part of a document used to declare any competing interests regarding the authors and/or funding organization for the work described in the document."@en ;
  rdfs:subClassOf obo:IAO_0000314 .

obo:OBI_0001143 a rdfs:Class ;
  rdfs:label "labeled nucleic acid extract" ;
  rdfs:comment "a labeled specimen that is the output of a labeling process and has grain labeled nucleic acid for detection of the nucleic acid in future experiments."@en ;
  rdfs:subClassOf obo:OBI_0000924 .

obo:NCBITaxon_40674 a rdfs:Class ;
  rdfs:label "Mammalia" ;
  rdfs:subClassOf obo:NCBITaxon_32524 .

obo:OBI_0002524 a rdfs:Class ;
  rdfs:label "urinary bladder specimen" ;
  rdfs:comment "A specimen that is derived from urinary bladder."@en ;
  rdfs:subClassOf obo:OBI_0001479 .

obo:UBERON_0007109 a rdfs:Class ;
  rdfs:label "meconium" ;
  rdfs:comment "A dark greenish mass that accumulates in the bowel during fetal life and is discharged shortly after birth." ;
  rdfs:subClassOf obo:UBERON_0001988 .

obo:IAO_0021010 a rdfs:Class ;
  rdfs:label "obsolete_obligation"@en ;
  rdfs:subClassOf <http://www.geneontology.org/formats/oboInOwl#ObsoleteClass> .

obo:ICO_0000385 a rdfs:Class ;
  rdfs:label "designated educational organization"@en ;
  rdfs:comment "A 'designated organization' that desginates an educational organization."@en ;
  rdfs:subClassOf obo:ICO_0000384 .

obo:OGMS_0000102 a rdfs:Class ;
  rdfs:label "injury" ;
  rdfs:comment "A disorder that involves some structural damage that is immediately caused by a catastrophic external force."@en ;
  rdfs:subClassOf obo:OGMS_0000045 .

obo:IAO_0000400 a rdfs:Class ;
  rdfs:label "cartesian spatial coordinate datum"@en ;
  rdfs:comment "A cartesian spatial coordinate datum is a representation of a point in a spatial region, in which equal changes in the magnitude of a coordinate value denote length qualities with the same magnitude"@en ;
  rdfs:subClassOf obo:IAO_0000027 .

obo:ICO_0000199 a rdfs:Class ;
  rdfs:label "permission role"@en ;
  rdfs:comment "A deontic role that inheres in an agent and which permits certain actions."@en ;
  rdfs:subClassOf obo:IAO_0021008 .

obo:DUO_0000035 a rdfs:Class ;
  rdfs:label "gender category research" ;
  rdfs:comment "An investigation concerning specific gender categories." ;
  rdfs:subClassOf obo:OBI_0000066 .

obo:NCBITaxon_10239 a rdfs:Class ;
  rdfs:label "Viruses" ;
  rdfs:subClassOf obo:OBI_0100026 .

obo:IAO_0000609 a rdfs:Class ;
  rdfs:label "author summary section"@en ;
  rdfs:comment "A part of a document, distinct from the abstract, that describes the significance and broader context of the document content. The author summary is often written in a non-technical manner and is aimed at both scientists and non-scientist readers."@en ;
  rdfs:subClassOf obo:IAO_0000314 .

obo:ICO_0000256 a rdfs:Class ;
  rdfs:label "legal age"@en ;
  rdfs:comment "A temporal region identifier that designates the temporal region during which a living person is alive, and where the temporal region is such that the living person is qualified to exercise a deontic power within a legal jurisdiction."@en ;
  rdfs:subClassOf obo:IAO_0000030 .

obo:IAO_0000027 a rdfs:Class ;
  rdfs:label "data item"@en ;
  rdfs:comment "An information content entity that is intended to be a truthful statement about something (modulo, e.g., measurement precision or other systematic errors) and is constructed/acquired by a method which reliably tends to produce (approximately) truthful statements."@en ;
  rdfs:subClassOf obo:IAO_0000030 .

obo:UBERON_0004648 a rdfs:Class ;
  rdfs:label "esophagus muscularis mucosa" ;
  rdfs:comment "A muscularis mucosa that is part of a esophagus." ;
  rdfs:subClassOf obo:UBERON_0000479 .

obo:IAO_0020022 a rdfs:Class ;
  rdfs:label "documented identity"@en ;
  rdfs:comment "A documented identity is the aggregate of all data items about an entity.  Notice that a documented identity is not itself a document since a document is intended to be understood as a whole and data items about an individual are usually scattered across different documents."@en ;
  rdfs:subClassOf obo:IAO_0000030 .

obo:ICO_0000291 a rdfs:Class ;
  rdfs:label "description of incentive"@en ;
  rdfs:comment "A descriptive information content entity that describes an entity that provides positive motivation for some material entity."@en ;
  rdfs:subClassOf <http://www.ontologyrepository.com/CommonCoreOntologies/DescriptiveInformationContentEntity> .

obo:NCBITaxon_2 a rdfs:Class ;
  rdfs:label "Bacteria" ;
  rdfs:subClassOf obo:OBI_0100026 .

obo:UBERON_0001255 a rdfs:Class ;
  rdfs:label "urinary bladder" ;
  rdfs:comment "Distensible musculomembranous organ situated in the anterior part of the pelvic cavity in which urine collects before excretion[MP]." ;
  rdfs:subClassOf obo:UBERON_0000465 .

obo:ICO_0000267 a rdfs:Class ;
  rdfs:label "vulnerable population directive"@en ;
  rdfs:comment "A directive information entity that prescribes some process in which vulnerable individuals participate."@en ;
  rdfs:subClassOf obo:IAO_0000033 .

obo:DUO_0000031 a rdfs:Class ;
  rdfs:label "method development" ;
  rdfs:comment "An investigation concerning development of methods, algorithms, software or analytical tools." ;
  rdfs:subClassOf obo:OBI_0000066 .

obo:OBI_0002558 a rdfs:Class ;
  rdfs:label "use of medication inclusion criterion"@en ;
  rdfs:comment "An inclusion criterion that defines and states a a set of medications, which, if used by an entity, makes that entity suitable for a given task or participation in a given process."@en ;
  rdfs:subClassOf obo:OBI_0500027 .

obo:OBI_0000876 a rdfs:Class ;
  rdfs:label "cytoplasmic RNA extract" ;
  rdfs:comment "A RNA extract that is the output of a RNA extraction process in which RNA molecules found in the cytoplasm are extracted."@en ;
  rdfs:subClassOf obo:OBI_0000880 .

obo:OGMS_0000090 a rdfs:Class ;
  rdfs:label "treatment" ;
  rdfs:comment "A planned process whose completion is hypothesized by a health care provider to eliminate, prevent, or alleviate a disorder, the signs and symptoms of a disorder, or a pathological process"@en ;
  rdfs:subClassOf obo:OBI_0000011 .

obo:OBI_0000097 a rdfs:Class ;
  rdfs:label "participant under investigation role"@en ;
  rdfs:comment "A role that is realized through the execution of a study design in which the bearer of the role participates and in which data about that bearer is collected."@en ;
  rdfs:subClassOf obo:BFO_0000023 .

obo:OBI_0002428 a rdfs:Class ;
  rdfs:label "BMI range inclusion criterion" ;
  rdfs:comment "An inclusion criterion that defines and states a Body Mass Index range, which if met, makes an individual suitable for a given task or participation in a given process."@en ;
  rdfs:subClassOf obo:OBI_0500027 .

obo:IAO_0000310 a rdfs:Class ;
  rdfs:label "document"@en ;
  rdfs:comment "A collection of information content entities intended to be understood together as a whole"@en ;
  rdfs:subClassOf obo:IAO_0000030 .

obo:ICO_0000247 a rdfs:Class ;
  rdfs:label "conditional restriction directive"@en ;
  rdfs:comment "A conditional specification that prescirbes an impermissibility, should some trigger condition obtain."@en ;
  rdfs:subClassOf obo:IAO_0000001 .

obo:OBI_2000010 a rdfs:Class ;
  rdfs:label "chorionic villus specimen" ;
  rdfs:comment "A specimen that is derived from some chorionic villus"@en ;
  rdfs:subClassOf obo:OBI_0002513 .

obo:IAO_0000707 a rdfs:Class ;
  rdfs:label "graphical abstract"@en ;
  rdfs:comment "An abstract that is pictorial summary of the main findings described in the document."@en ;
  rdfs:subClassOf obo:IAO_0000315 .

obo:OBI_0000086 a rdfs:Class ;
  rdfs:label "reagent role"@en ;
  rdfs:comment "A role inhering in a biological or chemical entity that is intended to be applied in a scientific technique to participate (or have molecular components that participate) in a chemical reaction that facilitates the generation of data about some entity distinct from the bearer, or the generation of some specified material output distinct from the bearer."@en ;
  rdfs:subClassOf obo:OBI_0003610 .

obo:ICO_0000260 a rdfs:Class ;
  rdfs:label "description of coercion"@en ;
  rdfs:comment "A descriptive information content entity that describes expressions or implications of threat that may compel an agent to act out of fear against the agent's will."@en ;
  rdfs:subClassOf <http://www.ontologyrepository.com/CommonCoreOntologies/DescriptiveInformationContentEntity> .

obo:BFO_0000062 a rdf:Property ;
  rdfs:label "preceded_by" ;
  rdfs:range <https://w3id.org/linkml/Any> .

obo:BFO_0000067 a rdf:Property ;
  rdfs:label "contains process"@en ;
  rdfs:comment "[copied from inverse property 'occurs in'] b occurs_in c =def b is a process and c is a material entity or immaterial entity& there exists a spatiotemporal region r and b occupies_spatiotemporal_region r.& forall(t) if b exists_at t then c exists_at t & there exist spatial regions s and s’ where & b spatially_projects_onto s at t& c is occupies_spatial_region s’ at t& s is a proper_continuant_part_of s’ at t"@en ;
  rdfs:range <https://w3id.org/linkml/Any> .

obo:BFO_0000179 a rdf:Property ;
  rdfs:label "BFO OWL specification label"@en ;
  rdfs:comment "Relates an entity in the ontology to the name of the variable that is used to represent it in the code that generates the BFO OWL file from the lispy specification."@en ;
  rdfs:range xsd:string .

obo:BFO_0000180 a rdf:Property ;
  rdfs:label "BFO CLIF specification label"@en ;
  rdfs:comment "Relates an entity in the ontology to the term that is used to represent it in the the CLIF specification of BFO2"@en ;
  rdfs:range xsd:string .

obo:DUO_0000041 a rdf:Property ;
  rdfs:label "DUO_preferred_label"@en ;
  rdfs:range xsd:string .

obo:IAO_0000111 a rdf:Property ;
  rdfs:label "editor preferred label" ;
  rdfs:comment "The concise, meaningful, and human-friendly name for a class or property preferred by the ontology developers. (US-English)"@en ;
  rdfs:range xsd:string .

obo:IAO_0000112 a rdf:Property ;
  rdfs:label "example of usage"@en ;
  rdfs:comment "A phrase describing how a term should be used and/or a citation to a work which uses it. May also include other kinds of examples that facilitate immediate understanding, such as widely know prototypes or instances of a class, or cases where a relation is said to hold."@en ;
  rdfs:range xsd:string .

obo:IAO_0000113 a rdf:Property ;
  rdfs:label "in branch"@en ;
  rdfs:comment "An annotation property indicating which module the terms belong to. This is currently experimental and not implemented yet."@en ;
  rdfs:range xsd:string .

obo:IAO_0000114 a rdf:Property ;
  rdfs:label "has curation status" ;
  rdfs:range xsd:string .

obo:IAO_0000115 a rdf:Property ;
  rdfs:label "textual definition" ;
  rdfs:comment "A property representing the English language definitions of what NCI means by the concept. They may also include information about the definition's source and attribution in a form that can easily be interpreted by software." ;
  rdfs:range xsd:string .

obo:IAO_0000116 a rdf:Property ;
  rdfs:label "editor note" ;
  rdfs:comment "An administrative note intended for its editor. It may not be included in the publication version of the ontology, so it should contain nothing necessary for end users to understand the ontology."@en ;
  rdfs:range xsd:string .

obo:IAO_0000117 a rdf:Property ;
  rdfs:label "term editor" ;
  rdfs:comment "Name of editor entering the term in the file. The term editor is a point of contact for information regarding the term. The term editor may be, but is not always, the author of the definition, which may have been worked upon by several people"@en ;
  rdfs:range xsd:string .

obo:IAO_0000118 a rdf:Property ;
  rdfs:label "alternative term" ;
  rdfs:comment "A label for a class or property that can be used to refer to the class or property instead of the preferred rdfs:label. Alternative labels should be used to indicate community- or context-specific labels, abbreviations, shorthand forms and the like."@en ;
  rdfs:range xsd:string .

obo:IAO_0000119 a rdf:Property ;
  rdfs:label "definition source" ;
  rdfs:comment "Formal citation, e.g. identifier in external database to indicate / attribute source(s) for the definition. Free text indicate / attribute source(s) for the definition. EXAMPLE: Author Name, URI, MeSH Term C04, PUBMED ID, Wiki uri on 31.01.2007"@en ;
  rdfs:range xsd:string .

obo:IAO_0000135 a rdf:Property ;
  rdfs:label "obsolete_specifically denotes" ;
  rdfs:comment """c specifically denotes r =def 
r is a portion of reality
& c is a particular quality
& c depends specifically on some independent continuant b 
& b acquired c as the result of the achievement of an objective to enable pointing to r repeatedly. 

Marked means there is a changed or additional quality of the bearer - the  quality is the information carrier.

Case 1
Memory trace as mark created when reading some description of some friend. The trace can denote.

Case 2
Pattern of ink arrayed on paper as mark when writing down a friend's name

Case 3
Pattern of magnetic domains on scattered pieces of a hard disk platter as mark when saving a file.""" ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf <http://www.geneontology.org/formats/oboInOwl#ObsoleteProperty> .

obo:IAO_0000142 a rdf:Property ;
  rdfs:label "mentions"@en ;
  rdfs:comment "An information artifact IA mentions an entity E exactly when it has a component/part that denotes E"@en ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:IAO_0000136 .

obo:IAO_0000220 a rdf:Property ;
  rdfs:label "obsolete_materially denotes" ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf <http://www.geneontology.org/formats/oboInOwl#ObsoleteProperty> .

obo:IAO_0000222 a rdf:Property ;
  rdfs:label "obsolete_describes" ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf <http://www.geneontology.org/formats/oboInOwl#ObsoleteProperty> .

obo:IAO_0000223 a rdf:Property ;
  rdfs:label "obsolete_represents" ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf <http://www.geneontology.org/formats/oboInOwl#ObsoleteProperty> .

obo:IAO_0000231 a rdf:Property ;
  rdfs:label "has obsolescence reason"@en ;
  rdfs:comment "Relates an annotation property to an obsolescence reason. The values of obsolescence reasons come from a list of predefined terms, instances of the class obsolescence reason specification."@en ;
  rdfs:range xsd:string .

obo:IAO_0000232 a rdf:Property ;
  rdfs:label "curator notes" ;
  rdfs:comment "An administrative note of use for a curator but of no use for a user"@en ;
  rdfs:range xsd:string .

obo:IAO_0000233 a rdf:Property ;
  rdfs:label "term tracker item"@en ;
  rdfs:comment "An IRI or similar locator for a request or discussion of an ontology term."@en ;
  rdfs:range xsd:string .

obo:IAO_0000234 a rdf:Property ;
  rdfs:label "ontology term requester"@en ;
  rdfs:comment "The name of the person, project, or organization that motivated inclusion of an ontology term by requesting its addition."@en ;
  rdfs:range xsd:string .

obo:IAO_0000411 a rdf:Property ;
  rdfs:label "is denotator type"@en ;
  rdfs:comment "Relates an class defined in an ontology, to the type of it's denotator"@en ;
  rdfs:range xsd:string .

obo:IAO_0000412 a rdf:Property ;
  rdfs:label "imported from" ;
  rdfs:comment "For external terms/classes, the ontology from which the term was imported"@en ;
  rdfs:range xsd:string .

obo:IAO_0000417 a rdf:Property ;
  rdfs:label "is quality measured as"@en ;
  rdfs:comment "inverse of the relation of is quality measurement of"@en ;
  rdfs:range <https://w3id.org/linkml/Any> .

obo:IAO_0000418 a rdf:Property ;
  rdfs:label "is quality specification of"@en ;
  rdfs:comment "A relation between a data item and a quality of a material entity where the material entity is the specified output of a material transformation which achieves an objective specification that indicates the intended value of the specified quality."@en ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:IAO_0000136 .

obo:IAO_0000419 a rdf:Property ;
  rdfs:label "quality is specified as"@en ;
  rdfs:comment "inverse of the relation of is quality specification of"@en ;
  rdfs:range <https://w3id.org/linkml/Any> .

obo:IAO_0000424 a rdf:Property ;
  rdfs:label "expand expression to"@en ;
  rdfs:comment "A macro expansion tag applied to an object property (or possibly a data property)  which can be used by a macro-expansion engine to generate more complex expressions from simpler ones"@en ;
  rdfs:range xsd:string .

obo:IAO_0000425 a rdf:Property ;
  rdfs:label "expand assertion to"@en ;
  rdfs:comment "A macro expansion tag applied to an annotation property which can be expanded into a more detailed axiom."@en ;
  rdfs:range xsd:string .

obo:IAO_0000426 a rdf:Property ;
  rdfs:label "first order logic expression"@en ;
  rdfs:range xsd:string .

obo:IAO_0000427 a rdf:Property ;
  rdfs:label "antisymmetric property"@en ;
  rdfs:comment "Use boolean value xsd:true to indicate that the property is an antisymmetric property"@en ;
  rdfs:range xsd:string .

obo:IAO_0000589 a rdf:Property ;
  rdfs:label "OBO foundry unique label"@en ;
  rdfs:comment "An alternative name for a class or property which is unique across the OBO Foundry."@en ;
  rdfs:range xsd:string .

obo:IAO_0000596 a rdf:Property ;
  rdfs:label "has ID digit count"@en ;
  rdfs:comment "Relates an ontology used to record id policy to the number of digits in the URI. The URI is: the 'has ID prefix\" annotation property value concatenated with an integer in the id range (left padded with \"0\"s to make this many digits)"@en ;
  rdfs:range xsd:string .

obo:IAO_0000597 a rdf:Property ;
  rdfs:label "has ID range allocated to"@en ;
  rdfs:comment "Relates a datatype that encodes a range of integers to the name of the person or organization who can use those ids constructed in that range to define new terms"@en ;
  rdfs:range xsd:string .

obo:IAO_0000598 a rdf:Property ;
  rdfs:label "has ID policy for"@en ;
  rdfs:comment "Relating an ontology used to record id policy to the ontology namespace whose policy it manages"@en ;
  rdfs:range xsd:string .

obo:IAO_0000599 a rdf:Property ;
  rdfs:label "has ID prefix"@en ;
  rdfs:comment "Relates an ontology used to record id policy to a prefix concatenated with an integer in the id range (left padded with \"0\"s to make this many digits) to construct an ID for a term being created."@en ;
  rdfs:range xsd:string .

obo:IAO_0000600 a rdf:Property ;
  rdfs:label "elucidation"@en ;
  rdfs:range xsd:string .

obo:IAO_0000601 a rdf:Property ;
  rdfs:label "has associated axiom(nl)"@en ;
  rdfs:range xsd:string .

obo:IAO_0000602 a rdf:Property ;
  rdfs:label "has associated axiom(fol)"@en ;
  rdfs:range xsd:string .

obo:IAO_0000603 a rdf:Property ;
  rdfs:label "is allocated id range"@en ;
  rdfs:comment "Relates an ontology IRI to an (inclusive) range of IRIs in an OBO name space. The range is give as, e.g. \"IAO_0020000-IAO_0020999\""@en ;
  rdfs:range xsd:string .

obo:IAO_0000604 a rdf:Property ;
  rdfs:label "retired from use as of" ;
  rdfs:comment "relates a class of CRID to the date after which further instances should not be made, according to the central authority" ;
  rdfs:range xsd:string .

obo:IAO_0000700 a rdf:Property ;
  rdfs:label "has ontology root term"@en ;
  rdfs:comment "Ontology annotation property. Relates an ontology to a term that is a designated root term of the ontology. Display tools like OLS can use terms annotated with this property as the starting point for rendering the ontology class hierarchy. There can be more than one root."@en ;
  rdfs:range xsd:string .

obo:IAO_0006011 a rdf:Property ;
  rdfs:label "may be identical to"@en ;
  rdfs:comment "A annotation relationship between two terms in an ontology that may refer to the same (natural) type but where more evidence is required before terms are merged."@en ;
  rdfs:range xsd:string .

obo:IAO_0006012 a rdf:Property ;
  rdfs:label "scheduled for obsoletion on or after"@en ;
  rdfs:comment "Used when the class or object is scheduled for obsoletion/deprecation on or after a particular date."@en ;
  rdfs:range xsd:dateTime .

obo:IAO_0010000 a rdf:Property ;
  rdfs:label "has axiom label"@en ;
  rdfs:range xsd:string .

obo:IAO_0021012 a rdf:Property ;
  rdfs:label "obsolete_legally transfers"@en ;
  rdfs:comment "d socio-legally transfers l if l participates in d and d has specified input  (concretization of l)1 and specified output  (concretization of l)2, where (concretization of l)1 and (concretization of l)2 are not identical."@en ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf <http://www.geneontology.org/formats/oboInOwl#ObsoleteProperty> .

obo:IAO_0100001 a rdf:Property ;
  rdfs:label "term replaced by"@en ;
  rdfs:comment "Use on obsolete terms, relating the term to another term that can be used as a substitute"@en ;
  rdfs:range xsd:string .

obo:ICO_0000067 a rdf:Property ;
  rdfs:label "obsolete form signed by" ;
  rdfs:comment "An object property that represents a relation between a form and the person or organization who acts as a signer and signs the form."@en ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf <http://www.geneontology.org/formats/oboInOwl#ObsoleteProperty> .

obo:ICO_0000091 a rdf:Property ;
  rdfs:label "term_mapping_to_UMLS"@en ;
  rdfs:range xsd:string .

obo:ICO_0000092 a rdf:Property ;
  rdfs:label "term_mapping_to_NCIT"@en ;
  rdfs:range xsd:string .

obo:ICO_0000093 a rdf:Property ;
  rdfs:label "term_mapping_to_HL7v3"@en ;
  rdfs:range xsd:string .

obo:ICO_0000130 a rdf:Property ;
  rdfs:label "obsolete is associated with review board approval number" ;
  rdfs:comment "A relation that links an informed consent form to an associated IRB number."@en ;
  rdfs:range obo:ICO_0000111 ;
  rdfs:subPropertyOf <http://www.geneontology.org/formats/oboInOwl#ObsoleteProperty> .

obo:ICO_0000132 a rdf:Property ;
  rdfs:label "obsolete is assigned by organization" ;
  rdfs:comment "An object property that represents a relation between a unique identifier (ID) and an organization that assigns the ID."@en ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf <http://www.geneontology.org/formats/oboInOwl#ObsoleteProperty> .

obo:ICO_0000183 a rdf:Property ;
  rdfs:label "has duration"@en ;
  rdfs:comment "Relates a process to a time-measurement-datum that represents the duration of the process" ;
  rdfs:range <https://w3id.org/linkml/Any> .

obo:ICO_0000216 a rdf:Property ;
  rdfs:label "permits"@en ;
  rdfs:comment "A relation holding between an instance of a deontic role and an instance of an intentional action when the deontic role bearer participates in the intentional action and is allowed to do so."@en ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:BFO_0000054 .

obo:ICO_0000321 a rdf:Property ;
  rdfs:label "RUBRIC"@en ;
  rdfs:range xsd:string .

obo:ICO_0000404 a rdf:Property ;
  rdfs:label "PICO CLASS"@en ;
  rdfs:comment "All classes and properties with this annotation are members of the PICO grammar."@en ;
  rdfs:range xsd:string .

obo:ICO_0000420 a rdf:Property ;
  rdfs:label "Merriam-Webster Definition"@en ;
  rdfs:range xsd:string .

obo:NCIT_NHC0 a rdf:Property ;
  rdfs:label "code" ;
  rdfs:comment "A property representing a concept unique identifier within the NCI Enterprise Vocabulary Service's NCI Thesaurus." ;
  rdfs:range xsd:string .

obo:NCIT_P106 a rdf:Property ;
  rdfs:label "Semantic_Type" ;
  rdfs:comment "A property that represents a description of the sort of thing or category to which a concept belongs in the context of the UMLS semantic network." ;
  rdfs:range xsd:string .

obo:NCIT_P107 a rdf:Property ;
  rdfs:label "Display_Name" ;
  rdfs:comment "A property representing an alternative Preferred Name for use in some NCI systems." ;
  rdfs:range xsd:string .

obo:NCIT_P108 a rdf:Property ;
  rdfs:label "Preferred_Name" ;
  rdfs:comment "A property representing the word or phrase that NCI uses by preference to refer to the concept." ;
  rdfs:range xsd:string .

obo:NCIT_P207 a rdf:Property ;
  rdfs:label "UMLS_CUI" ;
  rdfs:comment "A property representing the concept unique identifier (CUI) assigned by the National Library of Medicine (NLM). If a concept in any NCI-maintained knowledgebase exists in the NLM Unified Medical Language System (UMLS), NCI includes the NLM CUI among the information we provide about the concept." ;
  rdfs:range xsd:string .

obo:NCIT_P322 a rdf:Property ;
  rdfs:label "Contributing_Source" ;
  rdfs:comment "A property is used to indicate when a non-EVS entity has contributed to, and has a stake in, a concept. This is used where such entities, within or outside NCI, have indicated the need to be able to track their own concepts. A single concept can have multiple instances of this property if multiple entities have such a defined stake." ;
  rdfs:range xsd:string .

obo:NCIT_P325 a rdf:Property ;
  rdfs:label "ALT_DEFINITION" ;
  rdfs:comment "A property representing the English language definition of a concept from a source other than NCI." ;
  rdfs:range xsd:string .

obo:NCIT_P366 a rdf:Property ;
  rdfs:label "Legacy Concept Name" ;
  rdfs:comment "A property representing a retired unique concept identifier created and stored as Concept Name by legacy EVS software. Use of these values was long discouraged, but continued as late as 2009 when creation of new values ceased and Concept Name was retired. Legacy values are intended solely to help resolve and update earlier coding." ;
  rdfs:range xsd:string .

obo:NCIT_P98 a rdf:Property ;
  rdfs:label "DesignNote" ;
  rdfs:comment "A property representing notations made by NCI vocabulary curators. They are intended to provide supplemental, unstructured information to the user or additional insight about the concept." ;
  rdfs:range xsd:string .

obo:OBI_0000295 a rdf:Property ;
  rdfs:label "is_specified_input_of"@en ;
  rdfs:comment "A relation between a planned process and a continuant participating in that process that is not created during  the process. The presence of the continuant during the process is explicitly specified in the plan specification which the process realizes the concretization of."@en ;
  rdfs:range obo:OBI_0000011 ;
  rdfs:subPropertyOf obo:RO_0000056 .

obo:OBI_0001847 a rdf:Property ;
  rdfs:label "ISA alternative term"@en ;
  rdfs:comment "An alternative term used by the ISA tools project (http://isa-tools.org)."@en ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:IAO_0000118 .

obo:OBI_0001886 a rdf:Property ;
  rdfs:label "NIAID GSCID-BRC alternative term"@en ;
  rdfs:comment "An alternative term used by the National Institute of Allergy and Infectious Diseases (NIAID) Genomic Sequencing Centers for Infectious Diseases (GSCID) and Bioinformatics Resource Centers (BRC)."@en ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:IAO_0000118 .

obo:RO_0000080 a rdf:Property ;
  rdfs:label "quality of"@en ;
  rdfs:comment "a relation between a quality and an independent continuant (the bearer), in which the quality specifically depends on the bearer for its existence"@en ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0000052 .

obo:RO_0000081 a rdf:Property ;
  rdfs:label "role of"@en ;
  rdfs:comment "a relation between a role and an independent continuant (the bearer), in which the role specifically depends on the bearer for its existence"@en ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0000052 .

obo:RO_0000086 a rdf:Property ;
  rdfs:label "has quality"@en ;
  rdfs:comment "a relation between an independent continuant (the bearer) and a quality, in which the quality specifically depends on the bearer for its existence"@en ;
  rdfs:range obo:BFO_0000019 ;
  rdfs:subPropertyOf obo:RO_0000053 .

obo:RO_0000092 a rdf:Property ;
  rdfs:label "disposition of"@en ;
  rdfs:comment "This relation is modeled after the BFO relation of the same name which was in BFO2, but is used in a more restricted sense - specifically, we model this relation as functional (inherited from characteristic-of). Note that this relation is now removed from BFO2020." ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0000052 .

obo:RO_0001001 a rdf:Property ;
  rdfs:label "derives into"@en ;
  rdfs:comment "a relation between two distinct material entities, the old entity and the new entity, in which the new entity begins to exist when the old entity ceases to exist, and the new entity inherits the significant portion of the matter of the old entity"@en ;
  rdfs:range <https://w3id.org/linkml/Any> .

obo:RO_0001015 a rdf:Property ;
  rdfs:label "location of"@en ;
  rdfs:comment "a relation between two independent continuants, the location and the target, in which the target is entirely within the location"@en ;
  rdfs:range <https://w3id.org/linkml/Any> .

obo:RO_0001900 a rdf:Property ;
  rdfs:label "temporal interpretation"@en ;
  rdfs:comment "An assertion that holds between an OWL Object Property and a temporal interpretation that elucidates how OWL Class Axioms that use this property are to be interpreted in a temporal context." ;
  rdfs:range xsd:string .

obo:RO_0002000 a rdf:Property ;
  rdfs:label "2D boundary of"@en ;
  rdfs:comment "a relation between a 2D immaterial entity (the boundary) and a material entity, in which the boundary delimits the material entity"@en ;
  rdfs:range <https://w3id.org/linkml/Any> .

obo:RO_0002180 a rdf:Property ;
  rdfs:label "has component"@en ;
  rdfs:comment "w 'has component' p if w 'has part' p and w is such that it can be directly disassembled into into n parts p, p2, p3, ..., pn, where these parts are of similar type." ;
  rdfs:seeAlso <http://ontologydesignpatterns.org/wiki/Submissions:Componency> ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:BFO_0000051 .

obo:RO_0002218 a rdf:Property ;
  rdfs:label "has active participant"@en ;
  rdfs:comment "x has participant y if and only if x realizes some active role that inheres in y" ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0000057 .

obo:RO_0002350 a rdf:Property ;
  rdfs:label "member of"@en ;
  rdfs:comment "is member of is a mereological relation between a item and a collection." ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:BFO_0000050 .

obo:RO_0002351 a rdf:Property ;
  rdfs:label "has member"@en ;
  rdfs:comment "has member is a mereological relation between a collection and an item." ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:BFO_0000051 .

obo:RO_0004096 a rdf:Property ;
  rdfs:label "DEPRECATED inheres in"@en ;
  rdfs:comment "DEPRECATED This relation is similar to but different in important respects to the characteristic-of relation. See comments on that relation for more information." ;
  rdfs:range <https://w3id.org/linkml/Any> .

obo:RO_0004097 a rdf:Property ;
  rdfs:label "DEPRECATED bearer of"@en ;
  rdfs:range <https://w3id.org/linkml/Any> .

<http://www.geneontology.org/formats/oboInOwl#ObsoleteProperty> a rdf:Property ;
  rdfs:range <https://w3id.org/linkml/Any> .

<http://www.ontologyrepository.com/CommonCoreOntologies/designated_by> a rdf:Property ;
  rdfs:label "designated by"@en ;
  rdfs:comment "The inverse of designates, which relates an Entity to some Information Content Entity."@en ;
  rdfs:range <https://w3id.org/linkml/Any> .

<http://www.ontologyrepository.com/CommonCoreOntologies/has_familial_relationship_to> a rdf:Property ;
  rdfs:label "has familial relationship to"@en ;
  rdfs:comment "A relationship between persons by virtue of ancestry or legal union."@en ;
  rdfs:range <https://w3id.org/linkml/Any> .

<http://www.ontologyrepository.com/CommonCoreOntologies/prescribed_by> a rdf:Property ;
  rdfs:label "prescribed by"@en ;
  rdfs:comment "The inverse of presecribes, which relates an Entity to some Directive Information Content Entity."@en ;
  rdfs:range <https://w3id.org/linkml/Any> .

obo:IAO_0000409 a rdfs:Class ;
  rdfs:label "denotator type"@en ;
  rdfs:comment "A denotator type indicates how a term should be interpreted from an ontological perspective."@en ;
  rdfs:subClassOf obo:IAO_0000102 .

obo:IAO_0000410 a obo:IAO_0000409 ;
  rdfs:label "universal"@en .

obo:IAO_0000420 a obo:IAO_0000409 ;
  rdfs:label "defined class"@en ;
  rdfs:comment "A defined class is a class that is defined by a set of logically necessary and sufficient conditions but is not a universal"@en .

obo:IAO_0000421 a obo:IAO_0000409 ;
  rdfs:label "named class expression"@en ;
  rdfs:comment "A named class expression is a logical expression that is given a name. The name can be used in place of the expression."@en .

obo:OBI_0000639 a rdfs:Class ;
  rdfs:label "material separation objective" ;
  rdfs:comment "is an objective to transform a material entity into spatially separated components."@en ;
  rdfs:subClassOf obo:OBI_0000456 .

obo:OBI_0000678 a obo:OBI_0000639 ;
  rdfs:label "portioning objective" ;
  rdfs:comment "A material separation objective aiming to separate material into multiple portions, each of which contains a similar composition of the input material."@en .

obo:OBI_0000681 a obo:OBI_0000639 ;
  rdfs:label "separation into different composition objective" ;
  rdfs:comment "A material separation objective aiming to separate a material entity that has parts of different types, and end with at least one output that is a material with parts of fewer types (modulo impurities)."@en .

obo:ICO_0000001 a rdfs:Class ;
  rdfs:label "informed consent form"@en ;
  rdfs:comment "A document that explains all relevant information to assist a human being in understanding the expectations and requirements of participation in a process, and is an instrument in obtaining consent and, after having obtained consent, is a record that such a consent has occurred."@en ;
  rdfs:subClassOf obo:IAO_0021007 .

obo:ICO_0000213 a obo:ICO_0000001 ;
  rdfs:label "incomplete informed consent form"@en ;
  rdfs:comment "A document act input document that explains all relevant information to assist a human being in understanding the expectations and requirements of participation in a process, and whose purpose is to assist in obtaining consent."@en .

obo:ICO_0000214 a obo:ICO_0000001 ;
  rdfs:label "complete informed consent form indicating consent"@en ;
  rdfs:comment "A document act input document that has, as part, an incomplete informed consent form, along with some additional parts, such as a signature, stamp, or initials, which serve as a record to an act of consent that had the incomplete informed consent form as a specified input."@en .

obo:IAO_0000225 a rdfs:Class ;
  rdfs:label "obsolescence reason specification"@en ;
  rdfs:comment "The reason for which a term has been deprecated. The allowed values come from an enumerated list of predefined terms. See the specification of these instances for more detailed definitions of each enumerated value."@en ;
  rdfs:subClassOf obo:IAO_0000102 .

obo:IAO_0000103 a obo:IAO_0000225 ;
  rdfs:label "failed exploratory term"@en ;
  rdfs:comment "The term was used in an attempt to structure part of the ontology but in retrospect failed to do a good job"@en .

obo:IAO_0000226 a obo:IAO_0000225 ;
  rdfs:label "placeholder removed"@en .

obo:IAO_0000227 a obo:IAO_0000225 ;
  rdfs:label "terms merged"@en .

obo:IAO_0000228 a obo:IAO_0000225 ;
  rdfs:label "term imported"@en .

obo:IAO_0000229 a obo:IAO_0000225 ;
  rdfs:label "term split"@en .

obo:IAO_0000078 a rdfs:Class ;
  rdfs:label "curation status specification"@en ;
  rdfs:comment "The curation status of the term. The allowed values come from an enumerated list of predefined terms. See the specification of these instances for more detailed definitions of each enumerated value."@en ;
  rdfs:subClassOf obo:IAO_0000102 .

obo:IAO_0000002 a obo:IAO_0000078 ;
  rdfs:label "example to be eventually removed"@en .

obo:IAO_0000120 a obo:IAO_0000078 ;
  rdfs:label "metadata complete"@en ;
  rdfs:comment "Class has all its metadata, but is either not guaranteed to be in its final location in the asserted IS_A hierarchy or refers to another class that is not complete."@en .

obo:IAO_0000121 a obo:IAO_0000078 ;
  rdfs:label "organizational term"@en ;
  rdfs:comment "Term created to ease viewing/sort terms for development purpose, and will not be included in a release"@en .

obo:IAO_0000122 a obo:IAO_0000078 ;
  rdfs:label "ready for release"@en ;
  rdfs:comment "Class has undergone final review, is ready for use, and will be included in the next release. Any class lacking \"ready_for_release\" should be considered likely to change place in hierarchy, have its definition refined, or be obsoleted in the next release.  Those classes deemed \"ready_for_release\" will also derived from a chain of ancestor classes that are also \"ready_for_release.\""@en .

obo:IAO_0000123 a obo:IAO_0000078 ;
  rdfs:label "metadata incomplete"@en ;
  rdfs:comment "Class is being worked on; however, the metadata (including definition) are not complete or sufficiently clear to the branch editors."@en .

obo:IAO_0000124 a obo:IAO_0000078 ;
  rdfs:label "uncurated"@en ;
  rdfs:comment "Nothing done yet beyond assigning a unique class ID and proposing a preferred term."@en .

obo:IAO_0000125 a obo:IAO_0000078 ;
  rdfs:label "pending final vetting"@en ;
  rdfs:comment "All definitions, placement in the asserted IS_A hierarchy and required minimal metadata are complete. The class is awaiting a final review by someone other than the term editor."@en .

obo:IAO_0000423 a obo:IAO_0000078 ;
  rdfs:label "to be replaced with external ontology term"@en ;
  rdfs:comment "Terms with this status should eventually replaced with a term from another ontology."@en .

obo:IAO_0000428 a obo:IAO_0000078 ;
  rdfs:label "requires discussion"@en ;
  rdfs:comment "A term that is metadata complete, has been reviewed, and problems have been identified that require discussion before release. Such a term requires editor note(s) to identify the outstanding issues."@en .
