PREFIX obo: <http://purl.obolibrary.org/obo/>
PREFIX rdf: <http://www.w3.org/1999/02/22-rdf-syntax-ns#>
PREFIX rdfs: <http://www.w3.org/2000/01/rdf-schema#>
PREFIX xsd: <http://www.w3.org/2001/XMLSchema#>

obo:DOID_0050177 a rdfs:Class ;
  rdfs:label "monogenic disease" ;
  rdfs:comment "A genetic disease that is the result of one or more abnormal alleles and may be dominant (a single copy of the abnormal allele is sufficient to give rise to the disease), semi-dominant, or recessive (requiring both copies of the gene to have an abnormal allele)." ;
  rdfs:subClassOf obo:DOID_630 .

obo:OBI_0000312 a rdf:Property ;
  rdfs:label "is_specified_output_of"@en ;
  rdfs:comment "A relation between a planned process and a continuant participating in that process. The presence of the continuant at the end of the process is explicitly specified in the objective specification which the process realizes the concretization of."@en ;
  rdfs:domain obo:BFO_0000002 ;
  rdfs:range obo:OBI_0000011 ;
  rdfs:subPropertyOf obo:RO_0000056 .

obo:RO_0000059 a rdf:Property ;
  rdfs:label "concretizes"@en ;
  rdfs:comment "A relationship between a specifically dependent continuant and a generically dependent continuant, in which the generically dependent continuant depends on some independent continuant in virtue of the fact that the specifically dependent continuant also depends on that same independent continuant. Multiple specifically dependent continuants can concretize the same generically dependent continuant."@en ;
  rdfs:domain obo:BFO_0000020 ;
  rdfs:range obo:BFO_0000031 .

obo:OBI_0000295 a rdf:Property ;
  rdfs:label "is_specified_input_of"@en ;
  rdfs:domain obo:BFO_0000001 ;
  rdfs:range obo:OBI_0000011 .

obo:BFO_0000050 a rdf:Property ;
  rdfs:label "part of" ;
  rdfs:comment """
a core relation that holds between a part and its whole
"""@en ;
  rdfs:seeAlso <http://ontologydesignpatterns.org/wiki/Community:Parts_and_Collections> , <http://ontologydesignpatterns.org/wiki/Submissions:PartOf> , <http://www.obofoundry.org/ro/#OBO_REL:part_of> ;
  rdfs:domain obo:BFO_0000001 ;
  rdfs:range obo:BFO_0000001 ;
  rdfs:subPropertyOf obo:RO_0002131 .

obo:RO_0004022 a rdf:Property ;
  rdfs:label "disease arises from feature"@en ;
  rdfs:comment "A relation that holds between the disease and a feature (a phenotype or other disease) where the physical basis of the disease is the feature."@en ;
  rdfs:domain obo:OGMS_0000031 ;
  rdfs:range xsd:string .

obo:RO_0000056 a rdf:Property ;
  rdfs:label "participates in"@en ;
  rdfs:comment "a relation between a continuant and a process, in which the continuant is somehow involved in the process"@en ;
  rdfs:domain obo:BFO_0000002 ;
  rdfs:range obo:BFO_0000003 .

obo:RO_0002609 a rdf:Property ;
  rdfs:label "related via dependence to" ;
  rdfs:comment """
A relationship that holds between two entities, where the relationship holds based on the presence or absence of statistical dependence relationship. The entities may be statistical variables, or they may be other kinds of entities such as diseases, chemical entities or processes.
""" ;
  rdfs:domain obo:BFO_0000001 ;
  rdfs:range obo:BFO_0000001 .

obo:RO_0002314 a rdf:Property ;
  rdfs:label "inheres in part of" ;
  rdfs:comment "q inheres in part of w if and only if there exists some p such that q inheres in p and p part of w." ;
  rdfs:domain obo:BFO_0000020 ;
  rdfs:range <https://w3id.org/linkml/Any> ;
  rdfs:subPropertyOf obo:RO_0002502 .

obo:RO_0000092 a rdf:Property ;
  rdfs:label "disposition of"@en ;
  rdfs:comment "inverse of has disposition" ;
  rdfs:domain obo:BFO_0000016 ;
  rdfs:range obo:BFO_0000004 ;
  rdfs:subPropertyOf obo:RO_0000052 .

obo:RO_0000052 a rdf:Property ;
  rdfs:label "inheres in" ;
  rdfs:comment "a relation between a specifically dependent continuant (the dependent) and an independent continuant (the bearer), in which the dependent specifically depends on the bearer for its existence"@en ;
  rdfs:domain obo:BFO_0000020 ;
  rdfs:range obo:BFO_0000004 ;
  rdfs:subPropertyOf obo:RO_0002502 , obo:RO_0002314 .

obo:BFO_0000054 a rdf:Property ;
  rdfs:label "realized in"@en ;
  rdfs:comment "Paraphrase of elucidation: a relation between a realizable entity and a process, where there is some material entity that is bearer of the realizable entity and participates in the process, and the realizable entity comes to be realized in the course of the process" ;
  rdfs:domain obo:BFO_0000017 ;
  rdfs:range obo:BFO_0000015 .

obo:BFO_0000113 a rdf:Property ;
  rdfs:range <https://w3id.org/linkml/Any> ;
  rdfs:subPropertyOf obo:IDO_0000664 .

obo:VSO_0000002 a rdfs:Class ;
  rdfs:label "auscultatory pulse rate measurement process"@en ;
  rdfs:subClassOf obo:VSO_0000031 .

obo:BFO_0000062 a rdf:Property ;
  rdfs:label "preceded by"@en ;
  rdfs:comment "x is preceded by y if and only if the time point at which y ends is before or equivalent to the time point at which x starts. Formally: x preceded by y iff ω(y) <= α(x), where α is a function that maps a process to a start point, and ω is a function that maps a process to an end point."@en ;
  rdfs:domain obo:BFO_0000003 ;
  rdfs:range obo:BFO_0000003 ;
  rdfs:subPropertyOf obo:RO_0002086 .

obo:BFO_0000063 a rdf:Property ;
  rdfs:label "precedes"@en ;
  rdfs:comment "x precedes y if and only if the time point at which x ends is before or equivalent to the time point at which y starts. Formally: x precedes y iff ω(x) <= α(y), where α is a function that maps a process to a start point, and ω is a function that maps a process to an end point."@en ;
  rdfs:domain obo:BFO_0000003 ;
  rdfs:range obo:BFO_0000003 ;
  rdfs:subPropertyOf obo:RO_0002222 .

obo:RO_0002091 a rdf:Property ;
  rdfs:label "starts during"@en ;
  rdfs:comment "X starts_during Y iff: (start(Y) before_or_simultaneous_with start(X)) AND (start(X) before_or_simultaneous_with end(Y))"@en ;
  rdfs:domain obo:BFO_0000003 ;
  rdfs:range obo:BFO_0000003 ;
  rdfs:subPropertyOf obo:RO_0002222 .

obo:RO_0002010 a rdf:Property ;
  rdfs:label "regulates in other organism" ;
  rdfs:comment "x 'regulates in other organism' y if and only if: (x is the realization of a function to exert an effect on the frequency, rate or extent of y) AND (the agents of x are produced by organism o1 and the agents of y are produced by organism o2)." ;
  rdfs:domain obo:BFO_0000015 ;
  rdfs:range obo:BFO_0000015 ;
  rdfs:subPropertyOf obo:RO_0002418 .

obo:BFO_0000066 a rdf:Property ;
  rdfs:label "occurs in" ;
  rdfs:comment "b occurs_in c =def b is a process and c is a material entity or immaterial entity& there exists a spatiotemporal region r and b occupies_spatiotemporal_region r.& forall(t) if b exists_at t then c exists_at t & there exist spatial regions s and s’ where & b spatially_projects_onto s at t& c is occupies_spatial_region s’ at t& s is a proper_continuant_part_of s’ at t"@en ;
  rdfs:domain obo:BFO_0000003 ;
  rdfs:range xsd:string .

obo:RO_0002501 a rdf:Property ;
  rdfs:label "causal relation between processes" ;
  rdfs:comment "p is causally related to q if and only if p or any part of p and q or any part of q are linked by a chain of events where each event pair is one of direct activation or direct inhibition. p may be upstream, downstream, part of or a container of q." ;
  rdfs:domain obo:BFO_0000003 ;
  rdfs:range obo:BFO_0000003 ;
  rdfs:subPropertyOf obo:RO_0002410 .

obo:RO_0002231 a rdf:Property ;
  rdfs:label "has start location"@en ;
  rdfs:comment "x 'has starts location' y if and only if there exists some process z such that x 'starts with' z and z 'occurs in' y" ;
  rdfs:domain obo:BFO_0000015 ;
  rdfs:range obo:BFO_0000004 ;
  rdfs:subPropertyOf obo:RO_0002479 .

obo:RO_0002232 a rdf:Property ;
  rdfs:label "has end location"@en ;
  rdfs:comment "x 'has end location' y if and only if there exists some process z such that x 'ends with' z and z 'occurs in' y" ;
  rdfs:domain obo:BFO_0000015 ;
  rdfs:range obo:BFO_0000004 ;
  rdfs:subPropertyOf obo:RO_0002479 .

obo:RO_0002608 a rdf:Property ;
  rdfs:label "has causal agent" ;
  rdfs:comment "Inverse of 'causal agent in'" ;
  rdfs:domain obo:BFO_0000015 ;
  rdfs:range obo:BFO_0000040 ;
  rdfs:subPropertyOf obo:RO_0002410 .

obo:RO_0002244 a rdf:Property ;
  rdfs:label "related via exposure to" ;
  rdfs:domain obo:BFO_0000015 ;
  rdfs:range obo:BFO_0000001 ;
  rdfs:subPropertyOf obo:RO_0002410 .

obo:RO_0002211 a rdf:Property ;
  rdfs:label "regulates"@en ;
  rdfs:comment "x regulates y if and only if the x is the realization of a function to exert an effect on the frequency, rate or extent of y" ;
  rdfs:domain obo:BFO_0000015 ;
  rdfs:range obo:BFO_0000015 ;
  rdfs:subPropertyOf obo:RO_0002411 .

obo:RO_0002410 a rdf:Property ;
  rdfs:label "causally related to"@en ;
  rdfs:comment "This relation groups causal relations between material entities and causal relations between processes" ;
  rdfs:domain obo:BFO_0000001 ;
  rdfs:range obo:BFO_0000001 ;
  rdfs:subPropertyOf obo:RO_0002609 .

obo:RO_0002479 a rdf:Property ;
  rdfs:label "has part that occurs in" ;
  rdfs:comment "p has part that occurs in c if and only if there exists some p1, such that p has_part p1, and p1 occurs in c." ;
  rdfs:domain obo:BFO_0000003 ;
  rdfs:range obo:BFO_0000004 .

obo:OBI_0000299 a rdf:Property ;
  rdfs:label "has_specified_output"@en ;
  rdfs:comment "A relation between a planned process and a continuant participating in that process. The presence of the continuant at the end of the process is explicitly specified in the objective specification which the process realizes the concretization of."@en ;
  rdfs:domain obo:OBI_0000011 ;
  rdfs:range obo:BFO_0000002 ;
  rdfs:subPropertyOf obo:RO_0000057 .

obo:BFO_0000055 a rdf:Property ;
  rdfs:label "realizes"@en ;
  rdfs:comment "Paraphrase of elucidation: a relation between a process and a realizable entity, where there is some material entity that is bearer of the realizable entity and participates in the process, and the realizable entity comes to be realized in the course of the process" ;
  rdfs:domain obo:BFO_0000015 ;
  rdfs:range obo:BFO_0000017 .

obo:RO_0000057 a rdf:Property ;
  rdfs:label "has participant"@en ;
  rdfs:comment "a relation between a process and a continuant, in which the continuant is somehow involved in the process"@en ;
  rdfs:domain obo:BFO_0000003 ;
  rdfs:range obo:BFO_0000002 .

obo:RO_0002222 a rdf:Property ;
  rdfs:label "temporally related to"@en ;
  rdfs:comment "A relation that holds between two occurrents. This is a grouping relation that collects together all the Allen relations." ;
  rdfs:domain obo:BFO_0000003 ;
  rdfs:range obo:BFO_0000003 .

obo:RO_0002334 a rdf:Property ;
  rdfs:label "regulated by"@en ;
  rdfs:comment "inverse of regulates" ;
  rdfs:domain obo:BFO_0000015 ;
  rdfs:range obo:BFO_0000015 ;
  rdfs:subPropertyOf obo:RO_0002427 .

obo:RO_0002414 a rdf:Property ;
  rdfs:label "transitively provides input for"@en ;
  rdfs:comment "transitive form of directly_provides_input_for" ;
  rdfs:domain obo:BFO_0000015 ;
  rdfs:range obo:BFO_0000015 ;
  rdfs:subPropertyOf obo:RO_0002411 .

obo:RO_0002012 a rdf:Property ;
  rdfs:label "occurent part of" ;
  rdfs:comment "A part of relation that applies only between occurents." ;
  rdfs:domain obo:BFO_0000003 ;
  rdfs:range obo:BFO_0000003 ;
  rdfs:subPropertyOf obo:RO_0002418 , obo:BFO_0000050 .

obo:OBI_0000293 a rdf:Property ;
  rdfs:label "has_specified_input"@en ;
  rdfs:comment "A relation between a planned process and a continuant participating in that process that is not created during  the process. The presence of the continuant during the process is explicitly specified in the plan specification which the process realizes the concretization of."@en ;
  rdfs:domain obo:OBI_0000011 ;
  rdfs:range obo:BFO_0000002 ;
  rdfs:subPropertyOf obo:RO_0000057 .

obo:DOID_2388 a rdfs:Class ;
  rdfs:label "renal artery disease" ;
  rdfs:subClassOf obo:DOID_0050828 .

obo:DOID_11162 a rdfs:Class ;
  rdfs:label "respiratory failure" ;
  rdfs:comment "A lung disease characterized by inadequate gas exchange by the respiratory system." ;
  rdfs:subClassOf obo:DOID_850 .

obo:IAO_0000623 a rdfs:Class ;
  rdfs:label "funding source declaration section"@en ;
  rdfs:comment "A part of a document used to detail information regarding the source of funding used in support of the generation of the document content."@en ;
  rdfs:subClassOf obo:IAO_0000314 .

obo:BFO_0000051 a rdf:Property ;
  rdfs:label "has part" ;
  rdfs:comment """
a core relation that holds between a whole and its part
"""@en ;
  rdfs:range <https://w3id.org/linkml/Any> ;
  rdfs:subPropertyOf obo:RO_0002131 .

obo:IAO_0000219 a rdf:Property ;
  rdfs:label "denotes"@en ;
  rdfs:comment "denotes is a primitive, instance-level, relation obtaining between an information content entity and some portion of reality. Denotation is what happens when someone creates an information content entity E in order to specifically refer to something. The only relation between E and the thing is that E can be used to 'pick out' the thing. This relation connects those two together. Freedictionary.com sense 3: To signify directly; refer to specifically"@en ;
  rdfs:domain obo:IAO_0000030 ;
  rdfs:range obo:BFO_0000001 ;
  rdfs:subPropertyOf obo:IAO_0000136 .

obo:IAO_0000136 a rdf:Property ;
  rdfs:label "is about"@en ;
  rdfs:comment "is_about is a (currently) primitive relation that relates an information artifact to an entity."@en ;
  rdfs:domain obo:IAO_0000030 ;
  rdfs:range obo:BFO_0000001 .

obo:RO_0000058 a rdf:Property ;
  rdfs:label "is concretized as"@en ;
  rdfs:comment "A relationship between a generically dependent continuant and a specifically dependent continuant, in which the generically dependent continuant depends on some independent continuant in virtue of the fact that the specifically dependent continuant also depends on that same independent continuant. A generically dependent continuant may be concretized as multiple specifically dependent continuants."@en ;
  rdfs:domain obo:BFO_0000031 ;
  rdfs:range obo:BFO_0000020 .

obo:OGMS_0000037 a rdfs:Class ;
  rdfs:label "abnormal homeostasis" ;
  rdfs:comment "Homeostasis that is clinically abnormal for an organism of a given type and age in a given environment."@en ;
  rdfs:subClassOf obo:OGMS_0000032 .

obo:BFO_0000034 a rdfs:Class ;
  rdfs:label "function"@en ;
  rdfs:subClassOf obo:BFO_0000016 .

obo:RO_0000079 a rdf:Property ;
  rdfs:label "function of"@en ;
  rdfs:comment "a relation between a function and an independent continuant (the bearer), in which the function specifically depends on the bearer for its existence"@en ;
  rdfs:domain obo:BFO_0000034 ;
  rdfs:range obo:BFO_0000004 ;
  rdfs:subPropertyOf obo:RO_0000052 .

obo:VSO_0000047 a rdfs:Class ;
  rdfs:label "vaginal temperature"@en ;
  rdfs:comment "The temperature of the lumen of the vagina." ;
  rdfs:subClassOf obo:VSO_0000007 .

obo:OGMS_0000051 a rdfs:Class ;
  rdfs:label "constitutional genetic disorder" ;
  rdfs:comment "A genetic disorder inherited during conception that is part of all cells in the organism."@en ;
  rdfs:subClassOf obo:OGMS_0000047 .

obo:RO_0002375 a rdf:Property ;
  rdfs:label "in branching relationship with"@en ;
  rdfs:comment "A relationship that holds between two material entities in a system of connected structures, where the branching relationship holds based on properties of the connecting network." ;
  rdfs:seeAlso <http://purl.obolibrary.org/obo/ro/docs/branching_part_of.png> ;
  rdfs:domain obo:BFO_0000040 ;
  rdfs:range obo:BFO_0000040 ;
  rdfs:subPropertyOf obo:RO_0002323 , obo:BFO_0000050 .

obo:RO_0002500 a rdf:Property ;
  rdfs:label "causal agent in" ;
  rdfs:comment """
A relationship between a material entity and a process where the material entity has some causal role that influences the process
""" ;
  rdfs:domain obo:BFO_0000040 ;
  rdfs:range obo:BFO_0000015 ;
  rdfs:subPropertyOf obo:RO_0002595 .

obo:RO_0000086 a rdf:Property ;
  rdfs:label "has_quality" ;
  rdfs:comment "a relation between an independent continuant (the bearer) and a quality, in which the quality specifically depends on the bearer for its existence"@en ;
  rdfs:domain obo:BFO_0000004 ;
  rdfs:range obo:BFO_0000019 ;
  rdfs:subPropertyOf obo:RO_0000053 .

obo:RO_0002325 a rdf:Property ;
  rdfs:label "colocalizes with"@en ;
  rdfs:comment "a colocalizes_with b if and only if  a is transiently or peripherally associated with b[GO]." ;
  rdfs:domain obo:BFO_0000040 ;
  rdfs:range obo:BFO_0000040 ;
  rdfs:subPropertyOf obo:RO_0002323 .

obo:RO_0002176 a rdf:Property ;
  rdfs:label "connects"@en ;
  rdfs:comment "c connects a if and only if there exist some b such that a and b are similar parts of the same system, and c connects b, specifically, c connects a with b. When one structure connects two others it unites some aspect of the function or role they play within the system." ;
  rdfs:domain obo:BFO_0000004 ;
  rdfs:range <https://w3id.org/linkml/Any> ;
  rdfs:subPropertyOf obo:RO_0002323 .

obo:RO_0002570 a rdf:Property ;
  rdfs:label "conduit for" ;
  rdfs:comment "x is a conduit for y iff y overlaps through the lumen_of of x, and y has parts on either side of the lumen of x." ;
  rdfs:domain obo:BFO_0000040 ;
  rdfs:range obo:BFO_0000040 ;
  rdfs:subPropertyOf obo:RO_0002131 .

obo:RO_0001020 a rdf:Property ;
  rdfs:label "is allergic trigger for"@en ;
  rdfs:comment "A relation between a material entity and a condition (a phenotype or disease) of a host, in which the material entity is not part of the host, and is considered harmless to non-allergic hosts, and the condition results in pathological processes that include an abnormally strong immune response against the material entity." ;
  rdfs:domain obo:BFO_0000040 ;
  rdfs:range obo:BFO_0000001 ;
  rdfs:subPropertyOf obo:RO_0003302 .

obo:RO_0001018 a rdf:Property ;
  rdfs:label "contained in"@en ;
  rdfs:domain obo:BFO_0000040 ;
  rdfs:range obo:BFO_0000004 .

obo:RO_0000087 a rdf:Property ;
  rdfs:label "has role"@en ;
  rdfs:comment "a relation between an independent continuant (the bearer) and a role, in which the role specifically depends on the bearer for its existence"@en ;
  rdfs:domain obo:BFO_0000004 ;
  rdfs:range obo:BFO_0000023 ;
  rdfs:subPropertyOf obo:RO_0000053 .

obo:RO_0002215 a rdf:Property ;
  rdfs:label "capable of"@en ;
  rdfs:comment """
A relation between a material entity (such as a cell) and a process, in which the material entity has the ability to carry out the process.
""" ;
  rdfs:domain obo:BFO_0000004 ;
  rdfs:range obo:BFO_0000015 ;
  rdfs:subPropertyOf obo:RO_0002216 .

obo:RO_0001015 a rdf:Property ;
  rdfs:label "location of"@en ;
  rdfs:comment "a relation between two independent continuants, the location and the target, in which the target is entirely within the location"@en ;
  rdfs:domain obo:BFO_0000004 ;
  rdfs:range obo:BFO_0000004 .

obo:RO_0000085 a rdf:Property ;
  rdfs:label "has function"@en ;
  rdfs:comment "a relation between an independent continuant (the bearer) and a function, in which the function specifically depends on the bearer for its existence"@en ;
  rdfs:domain obo:BFO_0000004 ;
  rdfs:range obo:BFO_0000034 ;
  rdfs:subPropertyOf obo:RO_0000053 .

obo:RO_0002150 a rdf:Property ;
  rdfs:label "continuous with"@en ;
  rdfs:comment "X continuous_with Y if and only if X and Y share a fiat boundary." ;
  rdfs:domain obo:BFO_0000004 ;
  rdfs:range obo:BFO_0000004 ;
  rdfs:subPropertyOf obo:RO_0002323 .

obo:RO_0000053 a rdf:Property ;
  rdfs:label "bearer of"@en ;
  rdfs:comment "a relation between an independent continuant (the bearer) and a specifically dependent continuant (the dependent), in which the dependent specifically depends on the bearer for its existence"@en ;
  rdfs:domain obo:BFO_0000004 ;
  rdfs:range obo:BFO_0000020 .

obo:RO_0002595 a rdf:Property ;
  rdfs:label """
causal relation between material entity and a process
""" ;
  rdfs:comment "A relationship that holds between a material entity and a process in which causality is involved, with either the material entity or some part of the material entity exerting some influence over the process, or the process influencing some aspect of the material entity." ;
  rdfs:domain obo:BFO_0000040 ;
  rdfs:range obo:BFO_0000015 ;
  rdfs:subPropertyOf obo:RO_0002410 .

obo:RO_0000091 a rdf:Property ;
  rdfs:label "has disposition"@en ;
  rdfs:comment "a relation between an independent continuant (the bearer) and a disposition, in which the disposition specifically depends on the bearer for its existence"@en ;
  rdfs:domain obo:BFO_0000004 ;
  rdfs:range obo:BFO_0000016 ;
  rdfs:subPropertyOf obo:RO_0000053 .

obo:RO_0002434 a rdf:Property ;
  rdfs:label "interacts with" ;
  rdfs:comment "A relationship that holds between two entities in which the processes executed by the two entities are causally connected." ;
  rdfs:seeAlso obo:MI_0914 ;
  rdfs:domain obo:BFO_0000040 ;
  rdfs:range obo:BFO_0000040 .

obo:RO_0001021 a rdf:Property ;
  rdfs:label "is autoimmune trigger for"@en ;
  rdfs:comment "A relation between a material entity and a condition (a phenotype or disease) of a host, in which the material entity is part of the host itself, and the condition results in pathological processes that include an abnormally strong immune response against the material entity." ;
  rdfs:domain obo:BFO_0000040 ;
  rdfs:range obo:BFO_0000001 ;
  rdfs:subPropertyOf obo:RO_0003302 .

obo:RO_0002220 a rdf:Property ;
  rdfs:label "adjacent to"@en ;
  rdfs:comment "x adjacent to y if and only if x and y share a boundary." ;
  rdfs:domain obo:BFO_0000004 ;
  rdfs:range obo:BFO_0000004 ;
  rdfs:subPropertyOf obo:RO_0002163 .

obo:RO_0002002 a rdf:Property ;
  rdfs:label "has 2D boundary"@en ;
  rdfs:comment "a relation between a material entity and a 2D immaterial entity (the boundary), in which the boundary delimits the material entity"@en ;
  rdfs:domain obo:BFO_0000040 ;
  rdfs:range obo:BFO_0000141 ;
  rdfs:subPropertyOf obo:RO_0002323 .

obo:RO_0001025 a rdf:Property ;
  rdfs:label "located in" ;
  rdfs:comment "a relation between two independent continuants, the target and the location, in which the target is entirely within the location"@en ;
  rdfs:domain obo:BFO_0000004 ;
  rdfs:range obo:BFO_0000004 .

obo:RO_0002216 a rdf:Property ;
  rdfs:label "capable of part of"@en ;
  rdfs:comment "c stands in this relationship to p if and only if there exists some p' such that c is capable_of p', and p' is part_of p." ;
  rdfs:domain obo:BFO_0000040 ;
  rdfs:range obo:BFO_0000015 ;
  rdfs:subPropertyOf obo:RO_0002500 , obo:RO_0002328 .

obo:RO_0002506 a rdf:Property ;
  rdfs:label "causal relation between material entities" ;
  rdfs:domain obo:BFO_0000040 ;
  rdfs:range obo:BFO_0000040 ;
  rdfs:subPropertyOf obo:RO_0002410 .

obo:VSO_0000032 a rdfs:Class ;
  rdfs:label "radial pulse rate"@en ;
  rdfs:comment "The pulse rate of the radial artery." ;
  rdfs:subClassOf obo:VSO_0000029 .

obo:IAO_0000417 a rdf:Property ;
  rdfs:label "is quality measured as"@en ;
  rdfs:comment "inverse of the relation of is quality measurement of"@en ;
  rdfs:domain obo:BFO_0000019 ;
  rdfs:range obo:IAO_0000109 .

obo:PATO_0002303 a rdfs:Class ;
  rdfs:label "decreased object quality" ;
  rdfs:subClassOf obo:PATO_0001241 , obo:PATO_0002301 .

obo:RO_0002573 a rdf:Property ;
  rdfs:label "has modifier" ;
  rdfs:comment "A relation that holds between an attribute or a qualifier and another attribute." ;
  rdfs:range <https://w3id.org/linkml/Any> .

obo:BFO_0000017 a rdfs:Class ;
  rdfs:label "realizable entity"@en ;
  rdfs:comment "A specifically dependent continuant  that inheres in continuant  entities and are not exhibited in full at every time in which it inheres in an entity or group of entities. The exhibition or actualization of a realizable entity is a particular manifestation, functioning or process that occurs under certain circumstances."@en ;
  rdfs:subClassOf obo:BFO_0000020 .

obo:IAO_0000612 a rdfs:Class ;
  rdfs:label "availability textual entity"@en ;
  rdfs:comment "A textual entity expressing the location of a resource, e.g. software, or the manner in which a resource can be obtained."@en ;
  rdfs:subClassOf obo:IAO_0000300 .

obo:DOID_74 a rdfs:Class ;
  rdfs:label "hematopoietic system disease" ;
  rdfs:comment "An immune system disease that has_material_basis_in hematopoietic cells." ;
  rdfs:subClassOf obo:DOID_7 .

obo:IAO_0000009 a rdfs:Class ;
  rdfs:label "datum label"@en ;
  rdfs:comment "A label is a symbol that is part of some other datum and is used to either partially define  the denotation of that datum or to provide a means for identifying the datum as a member of the set of data with the same label"@en ;
  rdfs:subClassOf obo:IAO_0000030 .

obo:HTN_00000051 a rdfs:Class ;
  rdfs:label "adult over 18 years of age measurement datum"@en ;
  rdfs:comment "An age measurement datum that is about a human being has a measurement value equal to or greater than 18 years" ;
  rdfs:subClassOf obo:OBI_0001167 .

obo:OBI_0001938 a rdf:Property ;
  rdfs:label "has value specification" ;
  rdfs:range <https://w3id.org/linkml/Any> .

obo:IAO_0000004 a rdf:Property ;
  rdfs:label "has measurement value"@en ;
  rdfs:domain obo:IAO_0000032 ;
  rdfs:range <https://w3id.org/linkml/Any> .

obo:IAO_0000413 a rdf:Property ;
  rdfs:label "is duration of"@en ;
  rdfs:comment "relates a process to a time-measurement-datum that represents the duration of the process"@en ;
  rdfs:domain obo:IAO_0000416 ;
  rdfs:range obo:BFO_0000015 ;
  rdfs:subPropertyOf obo:IAO_0000136 .

obo:IAO_0000039 a rdf:Property ;
  rdfs:label "has measurement unit label"@en ;
  rdfs:domain obo:IAO_0000109 ;
  rdfs:range obo:UO_0000003 , obo:IAO_0000003 , obo:UO_0000002 ;
  rdfs:subPropertyOf obo:BFO_0000051 .

obo:IAO_0000418 a rdf:Property ;
  rdfs:label "is quality specification of"@en ;
  rdfs:comment "a relation between a data item and a quality of a material entity where the material entity is the specified output of a material transformation which achieves an objective specification that indicates the intended value of the specified quality."@en ;
  rdfs:domain obo:IAO_0000027 ;
  rdfs:range obo:BFO_0000001 ;
  rdfs:subPropertyOf obo:IAO_0000136 .

obo:IAO_0000221 a rdf:Property ;
  rdfs:label "is quality measurement of"@en ;
  rdfs:comment """m is a quality measurement of q at t when
q is a quality 
there is a measurement process p that has specified output m, a measurement datum, that is about q"""@en ;
  rdfs:domain obo:IAO_0000109 ;
  rdfs:range obo:BFO_0000019 , obo:PATO_0000125 ;
  rdfs:subPropertyOf obo:IAO_0000136 .

obo:IAO_0000443 a rdfs:Class ;
  rdfs:label "data item extraction from journal article" ;
  rdfs:comment "a planned process in which journal articles are read or processed and data items are extracted, typically for further analysis or indexing" ;
  rdfs:subClassOf obo:OBI_0000011 .

obo:IAO_0000055 a rdfs:Class ;
  rdfs:label "rule"@en ;
  rdfs:comment "a rule is an executable which guides, defines, restricts actions"@en ;
  rdfs:subClassOf obo:IAO_0000001 .

obo:BFO_0000145 a rdfs:Class ;
  rdfs:label "relational quality"@en ;
  rdfs:comment "b is a relational quality = Def. for some independent continuants c, d and for some time t: b quality_of c at t & b quality_of d at t. (axiom label in BFO2 Reference: [057-001])"@en ;
  rdfs:subClassOf obo:BFO_0000019 .

obo:DOID_9428 a rdfs:Class ;
  rdfs:label "intracranial hypertension" ;
  rdfs:subClassOf obo:DOID_936 .

obo:IAO_0000416 a rdfs:Class ;
  rdfs:label "time measurement datum"@en ;
  rdfs:comment "A scalar measurement datum that is the result of measuring a temporal interval"@en ;
  rdfs:subClassOf obo:IAO_0000032 .

obo:OBI_0001933 a rdfs:Class ;
  rdfs:label "value specification" ;
  rdfs:subClassOf obo:IAO_0000030 .

obo:DOID_6929 a rdfs:Class ;
  rdfs:label "retinal edema" ;
  rdfs:subClassOf obo:DOID_5679 .

obo:IAO_0000319 a rdfs:Class ;
  rdfs:label "discussion section of a publication about an investigation"@en ;
  rdfs:comment "A part of a publication about an investigation that is about the study interpretation of the investigation"@en ;
  rdfs:subClassOf obo:IAO_0000314 .

obo:NCBITaxon_131567 a rdfs:Class ;
  rdfs:label "cellular organisms" ;
  rdfs:subClassOf obo:BFO_0000030 .

obo:RO_0002200 a rdf:Property ;
  rdfs:label "has phenotype" ;
  rdfs:comment "A relationship that holds between a biological entity and a phenotype. Here a phenotype is construed broadly as any kind of quality of an organism part, a collection of these qualities, or a change in quality or qualities (e.g. abnormally increased temperature). The subject of this relationship can be an organism (where the organism has the phenotype, i.e. the qualities inhere in parts of this organism), a genomic entity such as a gene or genotype (if modifications of the gene or the genotype causes the phenotype), or a condition such as a disease (such that if the condition inheres in an organism, then the organism has the phenotype)." ;
  rdfs:domain obo:CARO_0030000 ;
  rdfs:range obo:OGMS_0000023 .

obo:IAO_0000645 a rdfs:Class ;
  rdfs:label "tables section"@en ;
  rdfs:comment "A part of a document that contains one or more tables."@en ;
  rdfs:subClassOf obo:IAO_0000314 .

obo:VSO_0000014 a rdfs:Class ;
  rdfs:label "diastole"@en ;
  rdfs:comment "The phase of the cardiac cycle in which the heart fills with blood." ;
  rdfs:subClassOf obo:VSO_0000011 .

obo:OGMS_0000022 a rdfs:Class ;
  rdfs:label "manifestation of a disease" ;
  rdfs:comment "A quality of a patient that is (a) a deviation from clinical normality that exists in virtue of the realization of a disease and (b) is observable."@en ;
  rdfs:subClassOf obo:BFO_0000019 .

obo:IAO_0000313 a rdfs:Class ;
  rdfs:label "patent"@en ;
  rdfs:comment "A document that has been accepted by a patent authority"@en ;
  rdfs:subClassOf obo:IAO_0000310 .

obo:DOID_0050739 a rdfs:Class ;
  rdfs:label "autosomal genetic disease" ;
  rdfs:comment "A monogenic disease that is has material basis in a mutation in a single gene on one of the non-sex chromosomes." ;
  rdfs:subClassOf obo:DOID_0050177 .

obo:VSO_0000025 a rdfs:Class ;
  rdfs:label "oral temperature"@en ;
  rdfs:comment "The temperature of the oral cavity." ;
  rdfs:subClassOf obo:VSO_0000007 .

obo:DOID_1729 a rdfs:Class ;
  rdfs:label "retinal vascular occlusion" ;
  rdfs:subClassOf obo:DOID_341 .

obo:IAO_0000013 a rdfs:Class ;
  rdfs:label "journal article"@en ;
  rdfs:comment "a report that is published in a journal"@en ;
  rdfs:subClassOf obo:IAO_0000088 .

obo:DOID_5656 a rdfs:Class ;
  rdfs:label "cranial nerve disease" ;
  rdfs:comment "A neuropathy that is located_in one of the twelve cranial nerves." ;
  rdfs:subClassOf obo:DOID_870 .

obo:IAO_0000302 a rdfs:Class ;
  rdfs:label "author identification"@en ;
  rdfs:comment "A textual entity intended to identify a particular author"@en ;
  rdfs:subClassOf obo:IAO_0000590 .

obo:GO_0032502 a rdfs:Class ;
  rdfs:label "developmental process" ;
  rdfs:subClassOf obo:GO_0008150 .

obo:HTN_00000005 a rdfs:Class ;
  rdfs:label "adult over 18 years of age"@en ;
  rdfs:comment "A human who is equal to or older than 18 years old"@en ;
  rdfs:subClassOf obo:NCBITaxon_9606 .

obo:DOID_0050117 a rdfs:Class ;
  rdfs:label "disease by infectious agent" ;
  rdfs:comment "A disease that is the consequence of the presence of pathogenic microbial agents, including pathogenic viruses, pathogenic bacteria, fungi, protozoa, multicellular parasites, and aberrant proteins known as prions." ;
  rdfs:subClassOf obo:OGMS_0000031 .

obo:BFO_0000030 a rdfs:Class ;
  rdfs:label "object" ;
  rdfs:subClassOf obo:BFO_0000040 .

obo:OMRSE_00000024 a rdfs:Class ;
  rdfs:label "role in human social processes"@en ;
  rdfs:comment "A role inhering in an entity realized by social interactions in human society."@en ;
  rdfs:subClassOf obo:BFO_0000023 .

obo:RO_0000081 a rdf:Property ;
  rdfs:label "role of"@en ;
  rdfs:comment "a relation between a role and an independent continuant (the bearer), in which the role specifically depends on the bearer for its existence"@en ;
  rdfs:domain obo:BFO_0000023 ;
  rdfs:range obo:BFO_0000004 ;
  rdfs:subPropertyOf obo:RO_0000052 .

obo:GO_0003013 a rdfs:Class ;
  rdfs:label "circulatory system process" ;
  rdfs:subClassOf obo:GO_0003008 .

obo:IAO_0000580 a rdfs:Class ;
  rdfs:label "looking up a centrally registered identifier"@en ;
  rdfs:comment "A planned process in which a request to a CRID registry is made to return the information associated with a CRID symbol"@en ;
  rdfs:subClassOf obo:OBI_0000011 .

obo:DOID_150 a rdfs:Class ;
  rdfs:label "disease of mental health" ;
  rdfs:comment "A disease that involves a psychological or behavioral pattern generally associated with subjective distress or disability that occurs in an individual, and which are not a part of normal development or culture." ;
  rdfs:subClassOf obo:OGMS_0000031 .

obo:VSO_0000036 a rdfs:Class ;
  rdfs:label "respiratory rate measurement process"@en ;
  rdfs:subClassOf obo:OBI_0000011 .

<http://purl.org/obo/owl/GO#GO_0001659> a rdfs:Class ;
  rdfs:label "regulation of temperature"@en ;
  rdfs:comment "A homeostatic process in which an organism modulates its internal body temperature." ;
  rdfs:subClassOf <http://purl.org/obo/owl/GO#GO_0065008> .

obo:IAO_0000183 a rdfs:Class ;
  rdfs:label "dendrogram"@en ;
  rdfs:comment """A dendrogram is a report graph which is a tree diagram
frequently used to illustrate the arrangement of the clusters produced by a
clustering algorithm."""@en ;
  rdfs:subClassOf obo:IAO_0000038 .

obo:OBI_0500000 a rdfs:Class ;
  rdfs:label "study design"@en ;
  rdfs:comment "A plan specification comprised of protocols (which may specify how and what kinds of data will be gathered) that are executed as part of an investigation and is realized during a study design execution." ;
  rdfs:subClassOf obo:IAO_0000104 .

obo:DOID_1312 a rdfs:Class ;
  rdfs:label "focal segmental glomerulosclerosis" ;
  rdfs:comment """Xref MGI.
OMIM mapping confirmed by DO. [SN].""" ;
  rdfs:subClassOf obo:DOID_0050851 .

obo:OGMS_0000084 a rdfs:Class ;
  rdfs:label "organism population" ;
  rdfs:comment "An aggregate of organisms of the same type."@en ;
  rdfs:subClassOf obo:BFO_0000040 .

obo:IAO_0000323 a rdfs:Class ;
  rdfs:label "author contributions section"@en ;
  rdfs:comment "A part of a publication that is about the specific contributions of each author"@en ;
  rdfs:subClassOf obo:IAO_0000314 .

obo:IAO_0000422 a rdfs:Class ;
  rdfs:label "postal address"@en ;
  rdfs:comment "A textual entity that is used as directive to deliver something to a person, or organization" ;
  rdfs:subClassOf obo:IAO_0000300 .

obo:GO_0072519 a rdfs:Class ;
  rdfs:label "parasitism" ;
  rdfs:subClassOf obo:GO_0044403 .

obo:IAO_0000606 a rdfs:Class ;
  rdfs:label "abbreviations section"@en ;
  rdfs:comment "A part of a document where abbreviations and their long-forms used within the document are listed."@en ;
  rdfs:subClassOf obo:IAO_0000314 .

obo:GO_0040007 a rdfs:Class ;
  rdfs:label "growth" ;
  rdfs:subClassOf obo:GO_0008150 .

obo:IAO_0000409 a rdfs:Class ;
  rdfs:label "denotator type" ;
  rdfs:comment "A denotator type indicates how a term should be interpreted from an ontological perspective." ;
  rdfs:subClassOf obo:IAO_0000102 .

obo:DOID_305 a rdfs:Class ;
  rdfs:label "carcinoma" ;
  rdfs:comment "A cell type cancer that has_material_basis_in abnormally proliferating cells derives_from epithelial cells." ;
  rdfs:subClassOf obo:DOID_0050687 .

<http://www.geneontology.org/formats/oboInOwl#Subset> a rdfs:Class ;
  rdfs:subClassOf obo:IAO_0000102 .

obo:BFO_0000006 a rdfs:Class ;
  rdfs:label "spatial region"@en ;
  rdfs:subClassOf obo:BFO_0000141 .

obo:RO_0002572 a rdf:Property ;
  rdfs:label "luminal space of" ;
  rdfs:comment "s is luminal space of x iff s is lumen_of x and s is an immaterial entity" ;
  rdfs:domain obo:BFO_0000141 ;
  rdfs:range obo:BFO_0000040 ;
  rdfs:subPropertyOf obo:RO_0002571 .

obo:RO_0002000 a rdf:Property ;
  rdfs:label "2D boundary of"@en ;
  rdfs:comment "a relation between a 2D immaterial entity (the boundary) and a material entity, in which the boundary delimits the material entity"@en ;
  rdfs:domain obo:BFO_0000141 ;
  rdfs:range obo:BFO_0000040 ;
  rdfs:subPropertyOf obo:RO_0002323 .

obo:OBI_0001167 a rdfs:Class ;
  rdfs:label "age measurement datum"@en ;
  rdfs:comment "A time measurement datum that is the result of measurement of age of an organism" ;
  rdfs:subClassOf obo:IAO_0000416 .

<http://purl.org/obo/owl/GO#GO_0008015> a rdfs:Class ;
  rdfs:label "blood circulation"@en ;
  rdfs:comment "The flow of blood through the body of an animal, enabling the transport of nutrients to the tissues and the removal of waste products." ;
  rdfs:subClassOf obo:BFO_0000015 .

obo:DOID_0050736 a rdfs:Class ;
  rdfs:label "autosomal dominant disease" ;
  rdfs:comment "An autosomal genetic disease that is characterized by the presence of one disease-associated mutation of a gene which is sufficient to cause the disease." ;
  rdfs:subClassOf obo:DOID_0050739 .

obo:BFO_0000182 a rdfs:Class ;
  rdfs:label "history"@en ;
  rdfs:subClassOf obo:BFO_0000015 .

obo:IAO_0000132 a rdfs:Class ;
  rdfs:label "lot number"@en ;
  rdfs:comment "A lot number is an information content entity which is an identical sequence of character borne by part of manufactured product or its packaging for each instances of a product class in a discrete batch of an item. Lot numbers are usually assigned to each separate production run of an item. Manufacturing as a lot might be due to a variety of reasons, for example,  a single process during which many individuals are made from the same portion of source material. Lot numbers can be encoded in a pattern  of other information objects, such as bar codes, numerals, or patterns of dots."@en ;
  rdfs:subClassOf obo:IAO_0000028 .

obo:GO_0007610 a rdfs:Class ;
  rdfs:label "behavior" ;
  rdfs:subClassOf obo:GO_0050896 .

obo:PATO_0000128 a rdfs:Class ;
  rdfs:label "weight" ;
  rdfs:subClassOf obo:PATO_0001035 .

obo:OGMS_0000082 a rdfs:Class ;
  rdfs:label "pathological invasion" ;
  rdfs:comment "TODO: Define."@en ;
  rdfs:subClassOf obo:OGMS_0000061 .

obo:IAO_0000628 a rdfs:Class ;
  rdfs:label "genome announcement textual entity"@en ;
  rdfs:comment "A textual entity that describes the generation and public release of a novel, draft genome sequence."@en ;
  rdfs:subClassOf obo:IAO_0000300 .

obo:PATO_0002246 a rdfs:Class ;
  rdfs:label "decreased force" ;
  rdfs:subClassOf obo:PATO_0001035 , obo:PATO_0002303 .

obo:DOID_583 a rdfs:Class ;
  rdfs:label "hemolytic anemia" ;
  rdfs:comment """OMIM mapping confirmed by DO. [SN].
OMIM mapping by NeuroDevNet. [LS].""" ;
  rdfs:subClassOf obo:DOID_720 .

obo:OGMS_0000098 a rdfs:Class ;
  rdfs:label "hospitalization" ;
  rdfs:comment "TODO"@en ;
  rdfs:subClassOf obo:OGMS_0000097 .

obo:VSO_0000021 a rdfs:Class ;
  rdfs:label "facial pulse rate"@en ;
  rdfs:comment "The pulse rate of the facial artery." ;
  rdfs:subClassOf obo:VSO_0000029 .

obo:IAO_0000403 a rdfs:Class ;
  rdfs:label "three dimensional cartesian spatial coordinate datum"@en ;
  rdfs:comment "A cartesion spatial coordinate datum that  uses three values to specify a position within a three dimensional spatial region"@en ;
  rdfs:subClassOf obo:IAO_0000400 .

obo:IAO_0000406 a rdf:Property ;
  rdfs:label "has y coordinate value"@en ;
  rdfs:domain obo:IAO_0000400 ;
  rdfs:range xsd:float .

obo:IAO_0000405 a rdf:Property ;
  rdfs:label "has z coordinate value"@en ;
  rdfs:domain obo:IAO_0000400 ;
  rdfs:range xsd:float .

obo:IAO_0000404 a rdf:Property ;
  rdfs:label "has x coordinate value"@en ;
  rdfs:domain obo:IAO_0000400 ;
  rdfs:range xsd:float .

obo:IAO_0000407 a rdf:Property ;
  rdfs:label "has coordinate unit label"@en ;
  rdfs:comment "relating a cartesian spatial coordinate datum to a unit label that together with the values represent a point"@en ;
  rdfs:domain obo:IAO_0000400 ;
  rdfs:range obo:UO_0000001 ;
  rdfs:subPropertyOf obo:BFO_0000051 .

obo:PATO_0001018 a rdfs:Class ;
  rdfs:label "physical quality" ;
  rdfs:subClassOf obo:PATO_0001241 .

obo:IAO_0000617 a rdfs:Class ;
  rdfs:label "conflict of interest textual entity"@en ;
  rdfs:comment "A textual entity that expresses a situation involving one or more of the authors, or the funding source of a document whereby the authors or funding source stand to potentially gain (typically financially) from the results reported in the document."@en ;
  rdfs:subClassOf obo:IAO_0000300 .

obo:OGMS_0000033 a rdfs:Class ;
  rdfs:label "genetic predisposition to disease of type X" ;
  rdfs:comment "A predisposition to disease of type X whose physical basis is a constitutional abnormality in an organism's genome. This abnormality is the physical basis for the increased risk of acquiring the disease X."@en ;
  rdfs:subClassOf obo:OGMS_0000030 .

obo:VSO_0000010 a rdfs:Class ;
  rdfs:label "brachial pulse rate"@en ;
  rdfs:comment "The pulse rate of the brachial artery." ;
  rdfs:subClassOf obo:VSO_0000029 .

obo:OGMS_0000073 a rdfs:Class ;
  rdfs:label "diagnosis" ;
  rdfs:comment "The representation of a conclusion of a diagnostic process."@en ;
  rdfs:subClassOf obo:IAO_0000027 .

obo:GO_0040011 a rdfs:Class ;
  rdfs:label "locomotion" ;
  rdfs:subClassOf obo:GO_0008150 .

obo:RO_0002565 a rdf:Property ;
  rdfs:label "results in movement of" ;
  rdfs:comment "Holds between p and c when p is locomotion process and the outcome of this process is the change of location of c" ;
  rdfs:domain obo:GO_0040011 ;
  rdfs:range obo:BFO_0000002 ;
  rdfs:subPropertyOf obo:RO_0000057 .

obo:OGMS_0000026 a rdfs:Class ;
  rdfs:label "preclinical manifestation of a disease" ;
  rdfs:comment "A manifestation of a disease that exists prior to the time at which it would be detected in a clinical history taking or physical examination, if the patient were to present to a clinician. A realization of a disease that exists prior to its becoming detectable in a clinical history taking or physical examination."@en ;
  rdfs:subClassOf obo:OGMS_0000022 .

obo:IAO_0000017 a rdfs:Class ;
  rdfs:label "model number"@en ;
  rdfs:comment "A model number is an information content entity specifically borne by catalogs, design specifications, advertising materials, inventory systems and similar  that is about manufactured objects of the same class. The model number is an alternative term for the class. The manufactered objects may or may not also bear the model number. Model numbers can be encoded in a variety of other information objects, such as bar codes, numerals, or patterns of dots."@en ;
  rdfs:subClassOf obo:IAO_0000028 .

obo:OGMS_0000016 a rdfs:Class ;
  rdfs:label "clinical picture" ;
  rdfs:comment "A representation of clinically significant bodily components, dispositions, and/or bodily processes of a human being that is inferred from relevant clinical findings."@en ;
  rdfs:subClassOf obo:IAO_0000027 .

obo:BFO_0000029 a rdfs:Class ;
  rdfs:label "site"@en ;
  rdfs:subClassOf obo:BFO_0000141 .

obo:IAO_0000001 a rdfs:Class ;
  rdfs:label "conditional specification"@en ;
  rdfs:comment "a directive information entity that specifies what should happen if the trigger condition is fulfilled"@en ;
  rdfs:subClassOf obo:IAO_0000033 .

obo:UO_0000003 a rdfs:Class ;
  rdfs:label "time unit" ;
  rdfs:comment "A unit which is a standard measure of the dimension in which events occur in sequence." ;
  rdfs:subClassOf obo:IAO_0000003 .

obo:DOID_14566 a rdfs:Class ;
  rdfs:label "disease of cellular proliferation" ;
  rdfs:comment "A disease that is characterized by abnormally rapid cell division." ;
  rdfs:subClassOf obo:OGMS_0000031 .

obo:HTN_00000044 a rdfs:Class ;
  rdfs:label "elevated adult diastolic blood pressure measurement datum"@en ;
  rdfs:comment "An elevated diastolic blood pressure measurement datum that is quality measurement of a diastolic blood pressure that inheres in an adult with a measurement value that is equal to or above some specified threshold for adults"@en ;
  rdfs:subClassOf obo:HTN_00000043 .

obo:DOID_10772 a rdfs:Class ;
  rdfs:label "thrombotic thrombocytopenic purpura" ;
  rdfs:subClassOf obo:DOID_2452 .

obo:DOID_1588 a rdfs:Class ;
  rdfs:label "thrombocytopenia" ;
  rdfs:comment "A blood platelet disease characterized by low a platelet count in the blood." ;
  rdfs:subClassOf obo:DOID_2218 .

obo:GO_0032501 a rdfs:Class ;
  rdfs:label "multicellular organismal process" ;
  rdfs:subClassOf obo:GO_0008150 .

obo:OGMS_0000105 a rdfs:Class ;
  rdfs:label "relapse"@en ;
  rdfs:comment "a disease stage which is preceded by a remission and characterized by the return of a manifestation of a disease." ;
  rdfs:subClassOf <http://purl.obolibrary.org/obo/ogms.owl#disease_stage> .

obo:DOID_11664 a rdfs:Class ;
  rdfs:label "nephrosclerosis" ;
  rdfs:subClassOf obo:DOID_1073 .

obo:GO_0044403 a rdfs:Class ;
  rdfs:label "symbiosis, encompassing mutualism through parasitism" ;
  rdfs:subClassOf obo:GO_0044419 .

obo:OGMS_0000040 a rdfs:Class ;
  rdfs:label "pathological physical configuration" ;
  rdfs:comment "A configuration which deviates in some way from a canonical configuration for a particular organism."@en ;
  rdfs:subClassOf obo:OGMS_0000039 .

obo:DOID_1324 a rdfs:Class ;
  rdfs:label "lung cancer" ;
  rdfs:comment "A respiratory system cancer that is located_in the lung." ;
  rdfs:subClassOf obo:DOID_0050615 , obo:DOID_850 .

obo:PATO_0002300 a rdfs:Class ;
  rdfs:label "increased quality" ;
  rdfs:subClassOf obo:PATO_0000069 .

obo:IAO_0000593 a rdfs:Class ;
  rdfs:label "software library"@en ;
  rdfs:comment "A software library is software composed of a collection of software modules and/or software methods in a form that can be statically or dynamically linked to some software application."@en ;
  rdfs:subClassOf obo:IAO_0000010 .

obo:DOID_783 a rdfs:Class ;
  rdfs:label "end stage renal failure" ;
  rdfs:subClassOf obo:DOID_784 .

obo:IAO_0000320 a rdfs:Class ;
  rdfs:label "references section"@en ;
  rdfs:comment "A part of a document that has citations as parts"@en ;
  rdfs:subClassOf obo:IAO_0000314 .

obo:DOID_403 a rdfs:Class ;
  rdfs:label "mouth disease" ;
  rdfs:comment "A gastrointestinal system disease that is located_in the mouth." ;
  rdfs:subClassOf obo:DOID_77 .

obo:DOID_8649 a rdfs:Class ;
  rdfs:label "tongue cancer" ;
  rdfs:subClassOf obo:DOID_10944 , obo:DOID_8618 .

<http://purl.obolibrary.org/obo/ogms.owl#disease_stage> a rdfs:Class ;
  rdfs:label "disease stage"@en ;
  rdfs:subClassOf obo:OGMS_0000063 .

obo:VSO_0000030 a rdfs:Class ;
  rdfs:label "pulse rate measurement datum"@en ;
  rdfs:subClassOf obo:IAO_0000109 .

<https://raw.githubusercontent.com/aellenhicks/htn_owl/master/htn.owl/_:genid12172> a rdfs:Class .

obo:BFO_0000162 a rdf:Property ;
  rdfs:domain <https://raw.githubusercontent.com/aellenhicks/htn_owl/master/htn.owl/_:genid12172> ;
  rdfs:range xsd:string .

obo:DOID_77 a rdfs:Class ;
  rdfs:label "gastrointestinal system disease" ;
  rdfs:comment "A disease of anatomical entity that is located_in the gastrointestinal tract." ;
  rdfs:subClassOf obo:DOID_7 .

obo:BFO_0000038 a rdfs:Class ;
  rdfs:label "one-dimensional temporal region"@en ;
  rdfs:subClassOf obo:BFO_0000008 .

obo:OGMS_0000081 a rdfs:Class ;
  rdfs:label "pathological derivation" ;
  rdfs:comment "A pathological bodily process in which matter is reorganized in such a way as to give rise to new pathological formations which take the place of entities existing earlier."@en ;
  rdfs:subClassOf obo:OGMS_0000061 .

obo:DOID_302 a rdfs:Class ;
  rdfs:label "substance abuse" ;
  rdfs:comment "A substance-related disorder that involves a maladaptive pattern of substance use leading to significant impairment in functioning." ;
  rdfs:subClassOf obo:DOID_303 .

obo:DOID_11130 a rdfs:Class ;
  rdfs:label "secondary hypertension" ;
  rdfs:subClassOf obo:DOID_10763 .

<http://purl.org/obo/owl/GO#GO_0008217> a rdfs:Class ;
  rdfs:label "regulation of blood pressure"@en ;
  rdfs:comment "Any process that modulates the force with which blood travels through the circulatory system. The process is controlled by a balance of processes that increase pressure and decrease pressure." ;
  rdfs:subClassOf <http://purl.org/obo/owl/GO#GO_0065008> .

obo:DOID_1443 a rdfs:Class ;
  rdfs:label "cerebral degeneration" ;
  rdfs:subClassOf obo:DOID_936 .

obo:VSO_0000041 a rdfs:Class ;
  rdfs:label "systolic pulmonary artery pressure"@en ;
  rdfs:comment "The pulmonary artery pressure during systole." ;
  rdfs:subClassOf obo:VSO_0000038 .

<http://purl.org/obo/owl/OBO_REL#exists_during> a rdf:Property ;
  rdfs:range <https://w3id.org/linkml/Any> .

obo:DOID_9352 a rdfs:Class ;
  rdfs:label "type 2 diabetes mellitus" ;
  rdfs:comment "A diabetes mellitus that involves high blood glucose resulting from cells fail to use insulin properly." ;
  rdfs:subClassOf obo:DOID_9351 .

obo:DOID_8712 a rdfs:Class ;
  rdfs:label "neurofibromatosis" ;
  rdfs:comment """Xref MGI.
OMIM mapping confirmed by DO. [SN].""" ;
  rdfs:subClassOf obo:DOID_0050736 .

obo:IAO_0000303 a rdfs:Class ;
  rdfs:label "institutional identification"@en ;
  rdfs:comment "A textual entity intended to identify a particular institution"@en ;
  rdfs:subClassOf obo:IAO_0000300 .

obo:IAO_0000314 a rdfs:Class ;
  rdfs:label "document part"@en ;
  rdfs:comment "an information content entity that is part of a document"@en ;
  rdfs:subClassOf obo:IAO_0000030 .

obo:IAO_0000630 a rdfs:Class ;
  rdfs:label "keywords section"@en ;
  rdfs:comment "A part of a document where keywords selected by the author to categorize the major theme(s) of a document are listed."@en ;
  rdfs:subClassOf obo:IAO_0000314 .

obo:IAO_0000098 a rdfs:Class ;
  rdfs:label "data format specification"@en ;
  rdfs:comment """A data format specification is the information content borne by the document published defining the specification.
Example: The ISO document specifying what encompasses an XML document; The instructions in a XSD file"""@en ;
  rdfs:subClassOf obo:IAO_0000033 .

obo:PATO_0000052 a rdfs:Class ;
  rdfs:label "shape" ;
  rdfs:subClassOf obo:PATO_0000051 .

obo:DOID_11400 a rdfs:Class ;
  rdfs:label "pyelonephritis" ;
  rdfs:subClassOf obo:DOID_2744 .

obo:VSO_0000043 a rdfs:Class ;
  rdfs:label "temporal pulse rate"@en ;
  rdfs:comment "The pulse rate of the temporal artery." ;
  rdfs:subClassOf obo:VSO_0000029 .

obo:HTN_00000050 a rdfs:Class ;
  rdfs:label "stage 2 adult blood pressure measurement datum per 2017 guidelines"@en ;
  rdfs:subClassOf obo:HTN_00000015 .

<https://raw.githubusercontent.com/aellenhicks/htn_owl/master/htn.owl/_:genid12156> a rdfs:Class .

obo:BFO_0000112 a rdf:Property ;
  rdfs:domain <https://raw.githubusercontent.com/aellenhicks/htn_owl/master/htn.owl/_:genid12156> ;
  rdfs:range xsd:string .

obo:PATO_0001241 a rdfs:Class ;
  rdfs:label "physical object quality" ;
  rdfs:subClassOf obo:BFO_0000019 .

obo:DOID_15 a rdfs:Class ;
  rdfs:label "reproductive system disease" ;
  rdfs:comment "A disease of anatomical entity that is located_in reproductive system organs." ;
  rdfs:subClassOf obo:DOID_7 .

obo:IAO_0000415 a rdfs:Class ;
  rdfs:label "hypothesis textual entity"@en ;
  rdfs:comment "A textual entity that expresses an assertion that is intended to be tested."@en ;
  rdfs:subClassOf obo:IAO_0000300 .

obo:OGMS_0000060 a rdfs:Class ;
  rdfs:label "bodily process" ;
  rdfs:subClassOf obo:BFO_0000015 .

obo:GO_0007631 a rdfs:Class ;
  rdfs:label "feeding behavior" ;
  rdfs:subClassOf obo:GO_0007610 .

obo:HTN_00000040 a rdfs:Class ;
  rdfs:label "stage 1 elevated adult systolic blood pressure meaurement datum per ACC 2017 guidelines"@en ;
  rdfs:comment """2017 Guideline for High Blood Pressure in Adults

http://www.onlinejacc.org/content/71/19/e127?_ga=2.55616109.754894593.1553089039-383350264.1553089039""" ;
  rdfs:subClassOf obo:HTN_00000003 .

obo:VSO_0000009 a rdfs:Class ;
  rdfs:label "body temperature measurement process"@en ;
  rdfs:subClassOf obo:OBI_0000011 .

obo:IAO_0000129 a rdfs:Class ;
  rdfs:label "version number"@en ;
  rdfs:comment "A version number is an information content entity which is a sequence of characters borne by part of each of a class of manufactured products or its packaging and indicates its order within a set of other products having the same name."@en ;
  rdfs:subClassOf obo:IAO_0000028 .

obo:DOID_0050758 a rdfs:Class ;
  rdfs:label "metabolic acidosis" ;
  rdfs:comment "An acquired metabolic disease that characterized by excessive production of acid." ;
  rdfs:subClassOf obo:DOID_0060158 .

obo:IAO_0000178 a rdfs:Class ;
  rdfs:label "material information bearer"@en ;
  rdfs:comment "A material entity in which a concretization of an information content entity inheres."@en ;
  rdfs:subClassOf obo:BFO_0000040 .

obo:OGMS_0000101 a rdfs:Class ;
  rdfs:label "ED encounter" ;
  rdfs:comment "TODO"@en ;
  rdfs:subClassOf obo:OGMS_0000097 .

obo:BFO_0000141 a rdfs:Class ;
  rdfs:label "immaterial entity"@en ;
  rdfs:subClassOf obo:BFO_0000004 .

obo:DOID_1076 a rdfs:Class ;
  rdfs:label "chronic pyelonephritis" ;
  rdfs:subClassOf obo:DOID_11400 .

obo:IAO_0000641 a rdfs:Class ;
  rdfs:label "requirements section"@en ;
  rdfs:comment "A part of a document about a resource described in the document, e.g. software, that describes the requirements necessary to use the resource, e.g. operating systems, hardware, etc. in the case of a software resource."@en ;
  rdfs:subClassOf obo:IAO_0000314 .

obo:DOID_0060085 a rdfs:Class ;
  rdfs:label "organ system benign neoplasm" ;
  rdfs:comment "A benign neoplasm that is classified by the organ system from which it is arising from." ;
  rdfs:subClassOf obo:DOID_0060072 .

obo:IAO_0000327 a rdfs:Class ;
  rdfs:label "table of contents"@en ;
  rdfs:comment "A table that relates document parts to specific locations in a document (usually page numbers).  This is also a document part (subsumption there should be inferred)."@en ;
  rdfs:subClassOf obo:IAO_0000306 .

obo:PATO_0000583 a rdfs:Class ;
  rdfs:label "decreased weight" ;
  rdfs:subClassOf obo:PATO_0000128 , obo:PATO_0002246 .

obo:DOID_5844 a rdfs:Class ;
  rdfs:label "myocardial infarction" ;
  rdfs:comment "A coronary artery disease characterized by myocardial cell death (myocardial necrosis) due to prolonged ischaemia." ;
  rdfs:subClassOf obo:DOID_3393 .

obo:OGMS_0000019 a rdfs:Class ;
  rdfs:label "preclinical finding" ;
  rdfs:comment "A representation of a quality of a patient that is (1) recorded by a clinician because the quality is hypothesized to be of clinical significance and (2) refers to qualities obtaining in the patient prior to their becoming detectable in a clinical history taking or physical examination."@en ;
  rdfs:subClassOf obo:IAO_0000027 .

obo:DOID_0050155 a rdfs:Class ;
  rdfs:label "sensory system disease" ;
  rdfs:comment "A nervous system disease which is located in a part of the nervous system responsible for processing sensory information that consists of sensory receptors, neural pathways, and parts of the brain involved in sensory perception. Commonly recognized sensory systems are those for vision, hearing, somatic sensation (touch), taste and olfaction (smell)." ;
  rdfs:subClassOf obo:DOID_863 .

obo:IAO_0000006 a rdfs:Class ;
  rdfs:label "narrative object"@en ;
  rdfs:comment "A narrative object is an information content entity that is a set of propositions."@en ;
  rdfs:subClassOf obo:IAO_0000030 .

obo:IAO_0000308 a rdfs:Class ;
  rdfs:label "figure"@en ;
  rdfs:comment "An information content entity consisting of a two dimensional arrangement of information content entities such that the arrangement itself is about something."@en ;
  rdfs:subClassOf obo:IAO_0000030 .

obo:DOID_2986 a rdfs:Class ;
  rdfs:label "IgA glomerulonephritis" ;
  rdfs:comment "A glomerulonephritis characterized by build up of IgA antibody in the glomerulus." ;
  rdfs:subClassOf obo:DOID_2921 .

obo:GO_0006952 a rdfs:Class ;
  rdfs:label "defense response" ;
  rdfs:subClassOf obo:GO_0006950 .

obo:IAO_0000028 a rdfs:Class ;
  rdfs:label "symbol"@en ;
  rdfs:comment "An information content entity that is a mark(s) or character(s) used as a conventional representation of another entity."@en ;
  rdfs:subClassOf obo:IAO_0000030 .

obo:OGMS_0000059 a rdfs:Class ;
  rdfs:label "etiological process" ;
  rdfs:comment "A process in an organism that leads to a subsequent disorder."@en ;
  rdfs:subClassOf obo:BFO_0000015 .

obo:PATO_0001035 a rdfs:Class ;
  rdfs:label "force" ;
  rdfs:subClassOf obo:PATO_0001018 .

obo:GO_0051816 a rdfs:Class ;
  rdfs:label "acquisition of nutrients from other organism during symbiotic interaction" ;
  rdfs:subClassOf obo:GO_0007631 .

obo:BFO_0000011 a rdfs:Class ;
  rdfs:label "spatiotemporal region"@en ;
  rdfs:subClassOf obo:BFO_0000003 .

obo:IAO_0000634 a rdfs:Class ;
  rdfs:label "notes section"@en ;
  rdfs:comment "A part of a document containing typically short notes about the document itself and/or the authors. Often the notes section contains subsections related to funding, competing interests, ethical approval, etc."@en ;
  rdfs:subClassOf obo:IAO_0000314 .

obo:BFO_0000040 a rdfs:Class ;
  rdfs:label "material entity" ;
  rdfs:comment """
An independent continuant that is spatially extended whose identity is independent of that of other entities and can be maintained through time.
"""@en ;
  rdfs:subClassOf obo:BFO_0000004 .

obo:DOID_345 a rdfs:Class ;
  rdfs:label "uterine disease" ;
  rdfs:comment "A female reproductive system disease that is located_in the uterus." ;
  rdfs:subClassOf obo:DOID_229 .

obo:DOID_104 a rdfs:Class ;
  rdfs:label "bacterial infectious disease" ;
  rdfs:comment "A disease by infectious agent that results_in infection, has_material_basis_in Bacteria." ;
  rdfs:subClassOf obo:DOID_0050117 .

obo:IDO_0000664 a rdf:Property ;
  rdfs:label "has material basis in" ;
  rdfs:range <https://w3id.org/linkml/Any> .

obo:IAO_0000402 a rdfs:Class ;
  rdfs:label "two dimensional cartesian spatial coordinate datum"@en ;
  rdfs:comment "A cartesion spatial coordinate datum that  uses two values to specify a position within a two dimensional spatial region"@en ;
  rdfs:subClassOf obo:IAO_0000400 .

obo:IAO_0000577 a rdfs:Class ;
  rdfs:label "centrally registered identifier symbol"@en ;
  rdfs:comment "A symbol that is part of a CRID and that is sufficient to look up a record from the CRID's registry."@en ;
  rdfs:subClassOf obo:IAO_0000028 .

obo:VSO_0000013 a rdfs:Class ;
  rdfs:label "core body temperature"@en ;
  rdfs:subClassOf obo:VSO_0000007 .

obo:HP_0000822 a rdfs:Class ;
  rdfs:label "Hypertension" ;
  rdfs:comment "The presence of chronic increased pressure in the systemic arterial system." ;
  rdfs:subClassOf obo:HTN_00000014 .

obo:RO_0002201 a rdf:Property ;
  rdfs:label "phenotype of"@en ;
  rdfs:comment "inverse of has phenotype" ;
  rdfs:domain obo:OGMS_0000023 ;
  rdfs:range obo:CARO_0030000 .

obo:HTN_00000028 a rdf:Property ;
  rdfs:label "feature gives rise to disease"@en ;
  rdfs:range <https://w3id.org/linkml/Any> .

obo:DOID_1679 a rdfs:Class ;
  rdfs:label "cystitis" ;
  rdfs:subClassOf obo:DOID_365 .

obo:DOID_8618 a rdfs:Class ;
  rdfs:label "oral cavity cancer" ;
  rdfs:comment "A gastrointestinal system cancer that is located_in the oral cavity." ;
  rdfs:subClassOf obo:DOID_3119 .

obo:VSO_0000042 a rdfs:Class ;
  rdfs:label "systolic right ventricular pressure"@en ;
  rdfs:comment "The right ventricular pressure during systole." ;
  rdfs:subClassOf obo:VSO_0000038 .

obo:ENVO_00000428 a rdfs:Class ;
  rdfs:label "biome" ;
  rdfs:subClassOf obo:ENVO_01000254 .

obo:RO_0002507 a rdf:Property ;
  rdfs:label "determined by" ;
  rdfs:comment "s determined by f if and only if s is a type of system, and f is a material entity that is part of s, such that f exerts a strong causal influence on the functioning of s, and the removal of f would cause the collapse of s." ;
  rdfs:domain obo:RO_0002577 ;
  rdfs:range obo:BFO_0000040 ;
  rdfs:subPropertyOf obo:RO_0002509 , obo:RO_0002559 , obo:BFO_0000050 .

obo:RO_0002509 a rdf:Property ;
  rdfs:label "determined by part of" ;
  rdfs:comment "s 'determined by part of' w if and only if there exists some f such that (1) s 'determined by' f and (2) f part_of w, or f=w." ;
  rdfs:domain obo:RO_0002577 ;
  rdfs:range obo:BFO_0000040 ;
  rdfs:subPropertyOf obo:RO_0002506 , obo:RO_0002131 .

obo:IAO_0000316 a rdfs:Class ;
  rdfs:label "introduction to a publication about an investigation"@en ;
  rdfs:comment "A part of a publication about an investigation that is about the objective specification (why the investigation is being done)"@en ;
  rdfs:subClassOf obo:IAO_0000314 .

obo:DOID_576 a rdfs:Class ;
  rdfs:label "proteinuria" ;
  rdfs:subClassOf obo:DOID_557 .

obo:HTN_00000004 a rdfs:Class ;
  rdfs:label "documented hypertensive phenotype"@en ;
  rdfs:comment "A phenotype of hypertension that has been documented"@en ;
  rdfs:subClassOf obo:HP_0000822 .

obo:DOID_0060095 a rdfs:Class ;
  rdfs:label "uterine benign neoplasm" ;
  rdfs:subClassOf obo:DOID_0060086 .

obo:PATO_0002323 a rdfs:Class ;
  rdfs:label "temporal distribution quality" ;
  rdfs:subClassOf obo:PATO_0002062 .

obo:VSO_0000005 a rdfs:Class ;
  rdfs:label "blood pressure measurement datum"@en ;
  rdfs:subClassOf obo:IAO_0000032 .

obo:VSO_0000024 a rdfs:Class ;
  rdfs:label "noninvasive blood pressure measurement process"@en ;
  rdfs:subClassOf obo:VSO_0000006 .

obo:IAO_0000100 a rdfs:Class ;
  rdfs:label "data set"@en ;
  rdfs:comment "A data item that is an aggregate of other data items of the same type that have something in common. Averages and distributions can be determined for data sets."@en ;
  rdfs:subClassOf obo:IAO_0000027 .

obo:DOID_1192 a rdfs:Class ;
  rdfs:label "peripheral nervous system neoplasm" ;
  rdfs:comment "A nervous system cancer that is located_in the peripheral nervous system." ;
  rdfs:subClassOf obo:DOID_3093 .

obo:OGMS_0000038 a rdfs:Class ;
  rdfs:label "normal homeostasis" ;
  rdfs:comment "Homeostasis of a type that is not clinically abnormal."@en ;
  rdfs:subClassOf obo:OGMS_0000032 .

obo:DOID_341 a rdfs:Class ;
  rdfs:label "peripheral vascular disease" ;
  rdfs:comment "A vascular disease that is characterized by obstruction of larger arteries not within the coronary, aortic arch vasculature, or brain." ;
  rdfs:subClassOf obo:DOID_178 .

obo:IAO_0000572 a rdfs:Class ;
  rdfs:label "documenting"@en ;
  rdfs:comment "a planned process in which a document is created or added to by including the specified input in it."@en ;
  rdfs:subClassOf obo:OBI_0000011 .

obo:VSO_0000031 a rdfs:Class ;
  rdfs:label "pulse rate measurement process"@en ;
  rdfs:subClassOf obo:OBI_0000011 .

obo:IAO_0000309 a rdfs:Class ;
  rdfs:label "diagram"@en ;
  rdfs:comment "A figure that expresses one or more propositions"@en ;
  rdfs:subClassOf obo:IAO_0000308 .

obo:CARO_0030000 a rdfs:Class ;
  rdfs:label "biological entity" ;
  rdfs:subClassOf obo:BFO_0000004 .

obo:PATO_0002266 a rdfs:Class ;
  rdfs:label "3-D shape" ;
  rdfs:subClassOf obo:PATO_0000052 .

obo:BFO_0000027 a rdfs:Class ;
  rdfs:label "object aggregate"@en ;
  rdfs:subClassOf obo:BFO_0000040 .

obo:DOID_2213 a rdfs:Class ;
  rdfs:label "hemorrhagic disease" ;
  rdfs:subClassOf obo:DOID_1247 .

obo:OGMS_0000039 a rdfs:Class ;
  rdfs:label "configuration" ;
  rdfs:comment "A quality which is an spatial arrangement or distribution of a(n) independent continuant(s) across a Three Dimensional Region."@en ;
  rdfs:subClassOf obo:BFO_0000019 .

<http://purl.org/obo/owl/GO#GO_0002027> a rdfs:Class ;
  rdfs:label "regulation of heart rate"@en ;
  rdfs:comment "Any process that modulates the frequency or rate of heart contraction." ;
  rdfs:subClassOf <http://purl.org/obo/owl/GO#GO_0065008> .

obo:OGMS_0000079 a rdfs:Class ;
  rdfs:label "portion of pathological body substance" ;
  rdfs:comment "TODO: Define, relate to disorder, and place in the OGMS hierarchy."@en ;
  rdfs:subClassOf obo:BFO_0000040 .

obo:IAO_0000625 a rdfs:Class ;
  rdfs:label "future directions section"@en ;
  rdfs:comment "A part of a document detailing extensions of the described work that may be implemented at some future point in time."@en ;
  rdfs:subClassOf obo:IAO_0000314 .

obo:BFO_0000023 a rdfs:Class ;
  rdfs:label "role"@en ;
  rdfs:comment "A realizable entity  the manifestation of which brings about some result or end that is not essential to a continuant  in virtue of the kind of thing that it is but that can be served or participated in by that kind of continuant  in some kinds of natural, social or institutional contexts."@en ;
  rdfs:subClassOf obo:BFO_0000017 .

obo:GO_0008150 a rdfs:Class ;
  rdfs:label "biological_process" ;
  rdfs:subClassOf obo:BFO_0000015 .

obo:PATO_0001237 a rdfs:Class ;
  rdfs:label "quality of a single physical entity"@en ;
  rdfs:comment "A physical object quality which inheres in a single-bearer."@en ;
  rdfs:subClassOf obo:BFO_0000019 .

obo:IAO_0000614 a rdfs:Class ;
  rdfs:label "case report textual entity"@en ;
  rdfs:comment "A textual entity that expresses a detailed account of a portion of the medical history for a specific patient."@en ;
  rdfs:subClassOf obo:IAO_0000300 .

obo:IAO_0000131 a rdfs:Class ;
  rdfs:label "serial number"@en ;
  rdfs:comment "A serial number is an information content entity which is a unique sequence of characters borne by part of manufactured product or its packaging that is assigned to each individual in some class of products, and so can serve as a way to identify an individual product within the class. Serial numbers can be encoded in a variety of other information objects, such as bar codes, numerals, or patterns of dots."@en ;
  rdfs:subClassOf obo:IAO_0000028 .

obo:DOID_1876 a rdfs:Class ;
  rdfs:label "sexual dysfunction" ;
  rdfs:subClassOf obo:DOID_0060043 .

obo:PATO_0002009 a rdfs:Class ;
  rdfs:label "branchiness" ;
  rdfs:subClassOf obo:PATO_0000052 .

obo:IAO_0000180 a rdfs:Class ;
  rdfs:label "heatmap"@en ;
  rdfs:comment """A heatmap is a report graph which is a graphical representation of data
where the values taken by a variable(s) are shown as colors in a
two-dimensional map."""@en ;
  rdfs:subClassOf obo:IAO_0000038 .

obo:VSO_0000046 a rdfs:Class ;
  rdfs:label "ulnar pulse rate"@en ;
  rdfs:comment "The pulse rate of the ulnar artery." ;
  rdfs:subClassOf obo:VSO_0000029 .

obo:OBI_0000471 a rdfs:Class ;
  rdfs:label "study design execution" ;
  rdfs:comment "a planned process that carries out a study design" ;
  rdfs:subClassOf obo:OBI_0000011 .

obo:OGMS_0000110 a rdfs:Class ;
  rdfs:label "health care process data transformation" ;
  rdfs:comment "A health care process that produces output from input data" ;
  rdfs:subClassOf obo:OGMS_0000096 .

obo:OGMS_0000092 a rdfs:Class ;
  rdfs:label "life course" ;
  rdfs:comment "A process which has as parts all the processes in which a given organism is participant."@en ;
  rdfs:subClassOf obo:BFO_0000015 .

obo:OGMS_0000109 a rdfs:Class ;
  rdfs:label "health care process biomaterial transformation " ;
  rdfs:comment "A health care process which results in physical changes in a specified input material " ;
  rdfs:subClassOf obo:OGMS_0000096 .

obo:IAO_0000644 a rdfs:Class ;
  rdfs:label "statistical analysis section"@en ;
  rdfs:comment "A part of the document used to describe the statistical methodologies employed in the work presented in the document."@en ;
  rdfs:subClassOf obo:IAO_0000314 .

obo:OGMS_0000017 a rdfs:Class ;
  rdfs:label "image finding" ;
  rdfs:comment "A representation of an image that supports an inference to an assertion about some quality of a patient."@en ;
  rdfs:subClassOf obo:OGMS_0000014 .

obo:IAO_0000330 a rdfs:Class ;
  rdfs:label "copyright section"@en ;
  rdfs:comment "A document part that describes  legal restrictions on making or distributing copies of the document"@en ;
  rdfs:subClassOf obo:IAO_0000314 .

obo:BFO_0000016 a rdfs:Class ;
  rdfs:label "disposition"@en ;
  rdfs:subClassOf obo:BFO_0000017 .

obo:IAO_0000611 a rdfs:Class ;
  rdfs:label "availability section"@en ;
  rdfs:comment "A part of a document about a resource described in the document, e.g. software, that describes where and/or how that resource can be obtained."@en ;
  rdfs:subClassOf obo:IAO_0000314 .

obo:GO_0008015 a rdfs:Class ;
  rdfs:label "blood circulation" ;
  rdfs:subClassOf obo:GO_0003013 .

obo:OGMS_0000057 a rdfs:Class ;
  rdfs:label "physical examination" ;
  rdfs:comment "A sequence of acts of observing and measuring qualities of a patient performed by a clinician; measurements may occur with and without elicitation."@en ;
  rdfs:subClassOf obo:OGMS_0000108 .

obo:IAO_0000030 a rdfs:Class ;
  rdfs:label "information content entity"@en ;
  rdfs:comment "An information content entity is an entity that is generically dependent on some artifact and stands in relation of aboutness to some entity"@en ;
  rdfs:subClassOf obo:BFO_0000031 .

obo:DOID_1936 a rdfs:Class ;
  rdfs:label "atherosclerosis" ;
  rdfs:subClassOf obo:DOID_2348 .

obo:VSO_0000020 a rdfs:Class ;
  rdfs:label "dorsalis pedis pulse rate"@en ;
  rdfs:comment "The pulse rate of the dorsalis pedis artery." ;
  rdfs:subClassOf obo:VSO_0000029 .

obo:IAO_0000442 a rdfs:Class ;
  rdfs:label "author role"@en ;
  rdfs:comment "A role inhering in a person or organization that is realized when the bearer participates in the work which is the basis of the document, in the writing of the document, and signs it with their name."@en ;
  rdfs:subClassOf obo:BFO_0000023 .

obo:PATO_0000122 a rdfs:Class ;
  rdfs:label "length" ;
  rdfs:comment "A 1-D extent quality which is equal to the distance between two points." ;
  rdfs:subClassOf obo:BFO_0000019 .

obo:IAO_0000633 a rdfs:Class ;
  rdfs:label "materials section"@en ;
  rdfs:comment "A part of a document about the materials required to reproduce the content of the document."@en ;
  rdfs:subClassOf obo:IAO_0000314 .

obo:IAO_0000622 a rdfs:Class ;
  rdfs:label "figures section"@en ;
  rdfs:comment "A part of a document that contains one or more figures."@en ;
  rdfs:subClassOf obo:IAO_0000314 .

obo:IAO_0000325 a rdfs:Class ;
  rdfs:label "footnote"@en ;
  rdfs:comment "A part of a document that is about a specific other part of the document.  Usually footnotes are spatially segregated from the rest of the document."@en ;
  rdfs:subClassOf obo:IAO_0000314 .

obo:IAO_0000636 a rdfs:Class ;
  rdfs:label "patients textual entity"@en ;
  rdfs:comment "A textual entity expressing information regarding the patients used in a study."@en ;
  rdfs:subClassOf obo:IAO_0000300 .

obo:PATO_0000460 a rdfs:Class ;
  rdfs:label "abnormal" ;
  rdfs:subClassOf obo:PATO_0000069 .

obo:VSO_0000035 a rdfs:Class ;
  rdfs:label "respiratory rate measurement datum"@en ;
  rdfs:subClassOf obo:IAO_0000109 .

obo:GO_0051704 a rdfs:Class ;
  rdfs:label "multi-organism process" ;
  rdfs:subClassOf obo:GO_0008150 .

obo:DOID_12215 a rdfs:Class ;
  rdfs:label "oligohydramnios" ;
  rdfs:comment "A placenta disease that is characterized by a deficiency of amniotic fluid sometimes resulting in an embryonic defect through adherence between embryo and amnion." ;
  rdfs:subClassOf obo:DOID_780 .

obo:HTN_00000043 a rdfs:Class ;
  rdfs:label "elevated diastolic blood pressure measurement datum"@en ;
  rdfs:comment "A diastolic blood pressure measurement datum with a measurement value that is equal to or above some specified threshold"@en ;
  rdfs:subClassOf obo:HTN_00000000 .

obo:DOID_630 a rdfs:Class ;
  rdfs:label "genetic disease" ;
  rdfs:comment "A disease that has_material_basis_in genetic variations in the human genome." ;
  rdfs:subClassOf obo:OGMS_0000031 .

obo:OGMS_0000087 a rdfs:Class ;
  rdfs:label "extended organism" ;
  rdfs:comment "An object aggregate consisting of an organism and all material entities located within the organism, overlapping the organism, or occupying sites formed in part by the organism."@en ;
  rdfs:subClassOf obo:BFO_0000040 .

obo:IAO_0000414 a rdfs:Class ;
  rdfs:label "mass measurement datum"@en ;
  rdfs:comment "A scalar measurement datum that is the result of measurement of mass quality"@en ;
  rdfs:subClassOf obo:IAO_0000032 .

obo:VSO_0000039 a rdfs:Class ;
  rdfs:label "systolic central venous pressure"@en ;
  rdfs:comment "The systolic blood pressure in the thoracic vena cava." ;
  rdfs:subClassOf obo:VSO_0000038 .

obo:BFO_0000026 a rdfs:Class ;
  rdfs:label "one-dimensional spatial region"@en ;
  rdfs:subClassOf obo:BFO_0000006 .

obo:NCBITaxon_9606 a rdfs:Class ;
  rdfs:label "Homo sapiens" ;
  rdfs:subClassOf obo:NCBITaxon_131567 .

obo:IAO_0000584 a rdfs:Class ;
  rdfs:label "time sampled measurement data set"@en ;
  rdfs:comment "A data set that is an aggregate of data recording some measurement at a number of time points. The time series data set is an ordered list of pairs of time measurement data and the corresponding measurement data acquired at that time."@en ;
  rdfs:subClassOf obo:IAO_0000100 .

obo:IAO_0000640 a rdfs:Class ;
  rdfs:label "related work textual entity"@en ;
  rdfs:comment "A textual entity that discusses work from other publications and expresses their relevancy to the content of a document."@en ;
  rdfs:subClassOf obo:IAO_0000300 .

obo:IAO_0000301 a rdfs:Class ;
  rdfs:label "citation"@en ;
  rdfs:comment "a textual entity intended to identify a particular publication"@en ;
  rdfs:subClassOf obo:IAO_0000300 .

obo:OGMS_0000104 a rdfs:Class ;
  rdfs:label "diagnostic process" ;
  rdfs:comment "A health care process that involves the interpretation of a clinical picture from a given patient (input) and the assertion to the effect that the patient has a disease, disorder, or syndrome of a certain type, or none of these (output)."@en ;
  rdfs:subClassOf obo:OGMS_0000096 .

obo:DOID_655 a rdfs:Class ;
  rdfs:label "inherited metabolic disorder" ;
  rdfs:comment "A disease of metabolism that is characterized by enzyme deficiency or accumulation of enzymes or toxins which interfere with normal function due to inherited enzyme abnormality." ;
  rdfs:subClassOf obo:DOID_0014667 .

obo:OGMS_0000024 a rdfs:Class ;
  rdfs:label "sign" ;
  rdfs:comment "A quality of a patient, a material entity that is part of a patient, or a processual entity that a patient participates in, any one of which is observed in a physical examination and is deemed by the clinician to be of clinical significance."@en ;
  rdfs:subClassOf obo:BFO_0000001 .

obo:DOID_0014667 a rdfs:Class ;
  rdfs:label "disease of metabolism" ;
  rdfs:comment "A disease that involving errors in metabolic processes of building or degradation of molecules." ;
  rdfs:subClassOf obo:OGMS_0000031 .

obo:DOID_0050686 a rdfs:Class ;
  rdfs:label "organ system cancer" ;
  rdfs:comment "A cancer that is classified based on the organ it starts in." ;
  rdfs:subClassOf obo:DOID_162 .

obo:IAO_0000618 a rdfs:Class ;
  rdfs:label "consent section"@en ;
  rdfs:comment "A part of a document about the consent process that was used to enroll patients in a study."@en ;
  rdfs:subClassOf obo:IAO_0000314 .

obo:OGMS_0000032 a rdfs:Class ;
  rdfs:label "homeostasis" ;
  rdfs:subClassOf obo:BFO_0000016 .

obo:BFO_0000001 a rdfs:Class ;
  rdfs:label "entity"@en .

obo:IAO_0000607 a rdfs:Class ;
  rdfs:label "author information section"@en ;
  rdfs:comment "A part of a document about the authors that provides biographical information and may discuss how the authors' professional experiences are relevant to the work described in the document."@en ;
  rdfs:subClassOf obo:IAO_0000314 .

obo:VSO_0000028 a rdfs:Class ;
  rdfs:label "popliteal pulse rate"@en ;
  rdfs:comment "The pulse rate of the popliteal artery." ;
  rdfs:subClassOf obo:VSO_0000029 .

obo:IAO_0000592 a rdfs:Class ;
  rdfs:label "software module"@en ;
  rdfs:comment " A software module is software composed of a collection of software methods."@en ;
  rdfs:subClassOf obo:IAO_0000010 .

obo:IAO_0000184 a rdfs:Class ;
  rdfs:label "scatter plot"@en ;
  rdfs:comment "A scatterplot is a graph which uses Cartesian coordinates to display values for two variables for a set of data. The data is displayed as a collection of points, each having the value of one variable determining the position on the horizontal axis and the value of the other variable determining the position on the vertical axis."@en ;
  rdfs:subClassOf obo:IAO_0000038 .

obo:OGMS_0000046 a rdfs:Class ;
  rdfs:label "epigenetic disorder" ;
  rdfs:comment "A disorder whose etiology involves (1) a modification to the patient's genomic DNA which leads to alterations in the normal expression pattern of the genome, but is (2) not a change in the nucleotide sequence."@en ;
  rdfs:subClassOf obo:OGMS_0000045 .

obo:DOID_6713 a rdfs:Class ;
  rdfs:label "cerebrovascular disease" ;
  rdfs:comment "An artery disease that is characterized by dysfunction of the blood vessels supplying the brain." ;
  rdfs:subClassOf obo:DOID_0050828 .

obo:IAO_0000324 a rdfs:Class ;
  rdfs:label "acknowledgements section"@en ;
  rdfs:comment "Part of a publication that is about the contributions of people or institutions other than the authors."@en ;
  rdfs:subClassOf obo:IAO_0000314 .

obo:IAO_0000007 a rdfs:Class ;
  rdfs:label "action specification"@en ;
  rdfs:comment "a directive information entity that describes an action the bearer will take"@en ;
  rdfs:subClassOf obo:IAO_0000033 .

obo:PATO_0000051 a rdfs:Class ;
  rdfs:label "morphology" ;
  rdfs:subClassOf obo:BFO_0000019 , obo:PATO_0001241 .

obo:IAO_0000088 a rdfs:Class ;
  rdfs:label "report"@en ;
  rdfs:comment "a document assembled by an author for the purpose of providing information for the audience. A report is the output of a documenting process and has the objective to be consumed by a specific audience. Topic of the report is on something that has completed. A report is not a single figure. Examples of reports are journal article, patent application, grant progress report, case report (not patient record)"@en ;
  rdfs:subClassOf obo:IAO_0000310 .

obo:VSO_0000006 a rdfs:Class ;
  rdfs:label "blood pressure measurement process"@en ;
  rdfs:subClassOf obo:OBI_0000011 .

obo:BFO_0000146 a rdfs:Class ;
  rdfs:label "two-dimensional continuant fiat boundary"@en ;
  rdfs:subClassOf obo:BFO_0000140 .

obo:DOID_0050161 a rdfs:Class ;
  rdfs:label "lower respiratory tract disease" ;
  rdfs:comment "A respiratory system disease which involves the lower respiratory tract." ;
  rdfs:subClassOf obo:DOID_1579 .

obo:DOID_1073 a rdfs:Class ;
  rdfs:label "renal hypertension" ;
  rdfs:subClassOf obo:DOID_11130 .

obo:OGMS_0000093 a rdfs:Class ;
  rdfs:label "prognosis" ;
  rdfs:comment "A hypothesis about some future part of a disease course."@en ;
  rdfs:subClassOf obo:IAO_0000027 .

obo:DOID_3905 a rdfs:Class ;
  rdfs:label "lung carcinoma" ;
  rdfs:comment "A lung cancer that has_material_basis_in abnormally proliferating cells derives_from epithelial cells and is located_in the lungs and has_symptom cough and has_symptom chest discomfort or pain and has_symptom weight loss and has_symptom hemoptysis." ;
  rdfs:subClassOf obo:DOID_1324 , obo:DOID_305 .

obo:DOID_863 a rdfs:Class ;
  rdfs:label "nervous system disease" ;
  rdfs:comment "A disease of anatomical entity that is located_in the central nervous system or located_in the peripheral nervous system." ;
  rdfs:subClassOf obo:DOID_7 .

obo:GO_0003008 a rdfs:Class ;
  rdfs:label "system process" ;
  rdfs:subClassOf obo:GO_0032501 .

obo:IAO_0000031 a rdfs:Class ;
  rdfs:label "integer numeral"@en ;
  rdfs:comment "a numeral that denotes an integer"@en ;
  rdfs:subClassOf obo:IAO_0000029 .

<http://www.geneontology.org/formats/oboInOwl#DbXref> a rdfs:Class ;
  rdfs:subClassOf obo:IAO_0000102 .

obo:BFO_0000004 a rdfs:Class ;
  rdfs:label "independent continuant"@en ;
  rdfs:comment "b is an independent continuant = Def. b is a continuant which is such that there is no c and no t such that b s-depends_on c at t. (axiom label in BFO2 Reference: [017-002])"@en ;
  rdfs:subClassOf obo:BFO_0000002 .

obo:IAO_0000573 a rdfs:Class ;
  rdfs:label "line graph"@en ;
  rdfs:comment """A line graph is a type of graph created by connecting a series of data
points together with a line."""@en ;
  rdfs:subClassOf obo:IAO_0000038 .

obo:DOID_11459 a rdfs:Class ;
  rdfs:label "pseudotumor cerebri" ;
  rdfs:comment "OMIM mapping confirmed by DO. [SN]." ;
  rdfs:subClassOf obo:DOID_6713 , obo:DOID_9428 .

obo:DOID_3021 a rdfs:Class ;
  rdfs:label "acute kidney failure" ;
  rdfs:subClassOf obo:DOID_1074 .

obo:GO_0044419 a rdfs:Class ;
  rdfs:label "interspecies interaction between organisms" ;
  rdfs:subClassOf obo:GO_0051704 .

obo:BFO_0000015 a rdfs:Class ;
  rdfs:label "process"@en ;
  rdfs:comment "p is a process = Def. p is an occurrent that has temporal proper parts and for some time t, p s-depends_on some material entity at t. (axiom label in BFO2 Reference: [083-003])"@en ;
  rdfs:subClassOf obo:BFO_0000003 .

obo:OGMS_0000065 a rdfs:Class ;
  rdfs:label "progressive disease course" ;
  rdfs:comment "A disease course that (a) does not terminate in a return to normal homeostasis and (b) would, absent intervention, involve an increasing deviation from homeostasis."@en ;
  rdfs:subClassOf obo:OGMS_0000063 .

obo:HTN_00000047 a rdfs:Class ;
  rdfs:label "stage 2 elevated adult systolic blood pressure meaurement datum per ACC 2017 guidelines"@en ;
  rdfs:subClassOf obo:HTN_00000003 .

obo:DOID_1532 a rdfs:Class ;
  rdfs:label "pleural disease" ;
  rdfs:comment "A thoracic disease which may involve inflammation of pleura, collection of air within the pleural cavity, abnormal collection of pleural fluid, abnormal growths on the pleura (pleural tumor) and pleural plaques. The main causes of pleural diseases including pleural effusions are congestive heart failure, malignancy, parapneumonic infections and pulmonary embolism." ;
  rdfs:subClassOf obo:DOID_0050161 .

obo:DOID_11502 a rdfs:Class ;
  rdfs:label "mitral valve insufficiency" ;
  rdfs:subClassOf obo:DOID_61 .

obo:DOID_18 a rdfs:Class ;
  rdfs:label "urinary system disease" ;
  rdfs:comment "A disease of anatomical entity that is located_in kidney, ureter, bladder and urethra." ;
  rdfs:subClassOf obo:DOID_7 .

obo:OGMS_0000108 a rdfs:Class ;
  rdfs:label "health care process assay" ;
  rdfs:comment "A health care process with the objective to produce information about the material entity that is the evaluant, by physically examining it or its proxies." ;
  rdfs:subClassOf obo:OGMS_0000096 .

obo:IAO_0000029 a rdfs:Class ;
  rdfs:label "numeral"@en ;
  rdfs:comment "A symbol that denotes a number."@en ;
  rdfs:subClassOf obo:IAO_0000028 .

obo:DOID_162 a rdfs:Class ;
  rdfs:label "cancer" ;
  rdfs:comment "A disease of cellular proliferation that is malignant and primary, characterized by uncontrolled cellular proliferation, local cell invasion and metastasis." ;
  rdfs:subClassOf obo:DOID_14566 .

obo:DOID_0060084 a rdfs:Class ;
  rdfs:label "cell type benign neoplasm" ;
  rdfs:comment "A benign neoplasm that is classified by the type of cell or tissue from which it is derived." ;
  rdfs:subClassOf obo:DOID_0060072 .

obo:DOID_3393 a rdfs:Class ;
  rdfs:label "coronary artery disease" ;
  rdfs:comment "An artery disease that is characterized by plaque building up along the inner walls of the arteries of the heart resulting in a narrowing of the arteries and a reduced blood supply to the cardiac muscles." ;
  rdfs:subClassOf obo:DOID_0050828 .

obo:IAO_0000312 a rdfs:Class ;
  rdfs:label "publication about an investigation"@en ;
  rdfs:comment "A publication that is about an investigation"@en ;
  rdfs:subClassOf obo:IAO_0000311 .

obo:HTN_00000003 a rdfs:Class ;
  rdfs:label "elevated adult systolic blood pressure measurement datum"@en ;
  rdfs:comment "A systolic blood pressure measurement datum that is about a blood pressure that inheres in an adult with a measurement value that is equal to or above some specified threshold for adults"@en ;
  rdfs:subClassOf obo:HTN_00000009 .

obo:DOID_12930 a rdfs:Class ;
  rdfs:label "dilated cardiomyopathy" ;
  rdfs:comment "An intrinsic cardiomyopathy that is characterized by an an enlarged heart and damage to the myocardium causing the heart to pump blood inefficiently." ;
  rdfs:subClassOf obo:DOID_0060036 .

<http://purl.org/obo/owl/GO#GO_0065008> a rdfs:Class ;
  rdfs:label "regulation of biological quality"@en ;
  rdfs:comment "Any process that modulates the frequency, rate or extent of a biological quality. A biological quality is a measurable attribute of an organism or part of an organism, such as size, mass, shape, color, etc." ;
  rdfs:subClassOf obo:BFO_0000015 .

obo:DOID_331 a rdfs:Class ;
  rdfs:label "central nervous system disease" ;
  rdfs:comment "A nervous system disease that affects either the spinal cord (myelopathy) or brain (encephalopathy) of the central nervous system." ;
  rdfs:subClassOf obo:DOID_863 .

obo:BFO_0000009 a rdfs:Class ;
  rdfs:label "two-dimensional spatial region"@en ;
  rdfs:subClassOf obo:BFO_0000006 .

obo:PATO_0002301 a rdfs:Class ;
  rdfs:label "decreased quality" ;
  rdfs:subClassOf obo:PATO_0000069 .

obo:BFO_0000028 a rdfs:Class ;
  rdfs:label "three-dimensional spatial region"@en ;
  rdfs:subClassOf obo:BFO_0000006 .

obo:DOID_3119 a rdfs:Class ;
  rdfs:label "gastrointestinal system cancer" ;
  rdfs:comment "An organ system cancer located_in gastrointestinal tract that is manifested in organs of the gastrointestinal system." ;
  rdfs:subClassOf obo:DOID_0050686 , obo:DOID_77 .

obo:OGMS_0000035 a rdfs:Class ;
  rdfs:label "constitutional genetic disease" ;
  rdfs:comment "A disease whose physical basis is a constitutional genetic disorder."@en ;
  rdfs:subClassOf obo:OGMS_0000031 .

obo:DOID_2921 a rdfs:Class ;
  rdfs:label "glomerulonephritis" ;
  rdfs:comment "A nephritis that causes inflammation of the glomeruli located_in kidney." ;
  rdfs:subClassOf obo:DOID_10952 .

obo:VSO_0000017 a rdfs:Class ;
  rdfs:label "diastolic left ventricular pressure"@en ;
  rdfs:comment "The left ventricular pressure during diastole." ;
  rdfs:subClassOf obo:VSO_0000015 .

obo:PATO_0001818 a rdfs:Class ;
  rdfs:label "progressive" ;
  rdfs:subClassOf obo:PATO_0000057 .

obo:IAO_0000104 a rdfs:Class ;
  rdfs:label "plan specification"@en ;
  rdfs:comment "A directive information entity with action specifications and objective specifications as parts that, when concretized, is realized in a process in which the bearer tries to achieve the objectives by taking the actions specified."@en ;
  rdfs:subClassOf obo:IAO_0000033 .

obo:BFO_0000142 a rdfs:Class ;
  rdfs:label "one-dimensional continuant fiat boundary"@en ;
  rdfs:subClassOf obo:BFO_0000140 .

obo:IAO_0000629 a rdfs:Class ;
  rdfs:label "keyword textual entity"@en ;
  rdfs:comment "A textual entity listing keywords indicating the major theme(s) of a document."@en ;
  rdfs:subClassOf obo:IAO_0000300 .

obo:DOID_4079 a rdfs:Class ;
  rdfs:label "heart valve disease" ;
  rdfs:comment "A heart disease involving one or more of the four valves of the heart (the aortic and mitral valves on the left and the pulmonary and tricuspid valves on the right)." ;
  rdfs:subClassOf obo:DOID_114 .

<http://www.geneontology.org/formats/oboInOwl#Definition> a rdfs:Class ;
  rdfs:subClassOf obo:IAO_0000102 .

<http://www.geneontology.org/formats/oboInOwl#Synonym> a rdfs:Class ;
  rdfs:subClassOf obo:IAO_0000102 .

obo:OGMS_0000091 a rdfs:Class ;
  rdfs:label "convalescence" ;
  rdfs:comment "A processual entity during which a patient participating in a disease course gradually returns to participating in a canonical life course. "@en ;
  rdfs:subClassOf obo:BFO_0000015 .

obo:OMRSE_00000010 a rdfs:Class ;
  rdfs:label "human health care role"@en ;
  rdfs:comment "A role in human social processes that is realized by health care processes such as seeking or providing treatment for disease and injury, diagnosing disease and injury, or undergoing diagnosis. "@en ;
  rdfs:subClassOf obo:OMRSE_00000024 .

obo:DOID_1591 a rdfs:Class ;
  rdfs:label "renovascular hypertension" ;
  rdfs:subClassOf obo:DOID_1073 .

obo:BFO_0000008 a rdfs:Class ;
  rdfs:label "temporal region"@en ;
  rdfs:subClassOf obo:BFO_0000003 .

obo:DOID_10763 a rdfs:Class ;
  rdfs:label "hypertension" ;
  rdfs:comment "An artery disease characterized by chronic elevated blood pressure in the arteries." ;
  rdfs:subClassOf obo:DOID_0050828 .

obo:PATO_0000069 a rdfs:Class ;
  rdfs:label "deviation(from_normal)" ;
  rdfs:subClassOf obo:PATO_0000068 .

obo:GO_0050878 a rdfs:Class ;
  rdfs:label "regulation of body fluid levels" ;
  rdfs:subClassOf obo:GO_0065008 .

obo:BFO_0000002 a rdfs:Class ;
  rdfs:label "continuant"@en ;
  rdfs:comment """
An entity that exists in full at any time in which it exists at all, persists through time while maintaining its identity and has no temporal parts.
"""@en ;
  rdfs:subClassOf obo:BFO_0000001 .

obo:IAO_0000306 a rdfs:Class ;
  rdfs:label "table"@en ;
  rdfs:comment "A textual entity that contains a two-dimensional arrangement of texts repeated at regular intervals across a spatial range, such that the spatial relationships among the constituent texts expresses propositions"@en ;
  rdfs:subClassOf obo:IAO_0000300 .

obo:IAO_0000317 a rdfs:Class ;
  rdfs:label "methods section"@en ;
  rdfs:comment "A part of a publication about an investigation that is about the study design of the investigation"@en ;
  rdfs:subClassOf obo:IAO_0000314 .

obo:IAO_0000401 a rdfs:Class ;
  rdfs:label "one dimensional cartesian spatial coordinate datum"@en ;
  rdfs:comment "A cartesion spatial coordinate datum that  uses one value to specify a position along a one dimensional spatial region"@en ;
  rdfs:subClassOf obo:IAO_0000400 .

obo:VSO_0000023 a rdfs:Class ;
  rdfs:label "invasive blood pressure measurement process"@en ;
  rdfs:subClassOf obo:VSO_0000006 .

obo:OBI_0000011 a rdfs:Class ;
  rdfs:label "planned process"@en ;
  rdfs:comment "A processual entity that realizes a plan which is the concretization of a plan specification."@en ;
  rdfs:subClassOf obo:BFO_0000015 .

obo:OBI_0001931 a rdfs:Class ;
  rdfs:label "scalar value specification" ;
  rdfs:subClassOf obo:IAO_0000030 .

obo:IAO_0000033 a rdfs:Class ;
  rdfs:label "directive information entity"@en ;
  rdfs:comment "An information content entity whose concretizations indicate to their bearer how to realize them in a process."@en ;
  rdfs:subClassOf obo:IAO_0000030 .

<https://raw.githubusercontent.com/aellenhicks/htn_owl/master/htn.owl/_:genid12140> a rdfs:Class .

obo:BFO_0000085 a rdf:Property ;
  rdfs:domain <https://raw.githubusercontent.com/aellenhicks/htn_owl/master/htn.owl/_:genid12140> ;
  rdfs:range xsd:string .

obo:HTN_00000009 a rdfs:Class ;
  rdfs:label "elevated systolic blood pressure measurement datum"@en ;
  rdfs:comment "Amanda Hicks" ;
  rdfs:subClassOf obo:HTN_00000001 .

obo:DOID_11396 a rdfs:Class ;
  rdfs:label "pulmonary edema" ;
  rdfs:subClassOf obo:DOID_11162 .

obo:IAO_0000326 a rdfs:Class ;
  rdfs:label "supplementary material to a document"@en ;
  rdfs:comment "part of a document that is segregated from the rest of the document due to its size"@en ;
  rdfs:subClassOf obo:IAO_0000314 .

obo:HTN_00000014 a rdfs:Class ;
  rdfs:label "elevated blood pressure phenotype"@en ;
  rdfs:comment "A phenotype of blood pressure that is above some specified threshold"@en ;
  rdfs:subClassOf obo:OGMS_0000023 .

obo:DOID_114 a rdfs:Class ;
  rdfs:label "heart disease" ;
  rdfs:comment "A cardiovascular system disease that involves the heart." ;
  rdfs:subClassOf obo:DOID_1287 .

obo:OMRSE_00000011 a rdfs:Class ;
  rdfs:label "patient role"@en ;
  rdfs:comment "A role borne by an organism and that is realized by presenting to a health care provider in a clinical encounter."@en ;
  rdfs:subClassOf obo:OMRSE_00000010 .

obo:IAO_0000064 a rdfs:Class ;
  rdfs:label "algorithm"@en ;
  rdfs:comment "A plan specification which describes the inputs and output of mathematical functions as well as workflow of execution for achieving an predefined objective. Algorithms are realized usually by means of implementation as computer programs for execution by automata."@en ;
  rdfs:subClassOf obo:IAO_0000104 .

obo:CARO_0000007 a rdfs:Class ;
  rdfs:label "immaterial anatomical entity" ;
  rdfs:subClassOf obo:BFO_0000141 .

obo:VSO_0000038 a rdfs:Class ;
  rdfs:label "systolic blood pressure"@en ;
  rdfs:comment "The blood pressure during systole." ;
  rdfs:subClassOf obo:VSO_0000004 .

obo:PATO_0001509 a rdfs:Class ;
  rdfs:label "functionality" ;
  rdfs:subClassOf obo:PATO_0001241 .

obo:IAO_0000610 a rdfs:Class ;
  rdfs:label "author summary textual entity"@en ;
  rdfs:comment "A textual entity, distinct from the abstract, that describes the significance and broader context of the document content. The author summary is often written in a non-technical manner and is aimed at both scientists and non-scientist readers, e.g as described in the article submission guidelines for PLoS Genetics (http://journals.plos.org/plosgenetics/s/submission-guidelines)."@en ;
  rdfs:subClassOf obo:IAO_0000300 .

obo:PATO_0000912 a rdfs:Class ;
  rdfs:label "increased rate" ;
  rdfs:subClassOf obo:PATO_0000161 , obo:PATO_0002304 .

obo:DOID_2355 a rdfs:Class ;
  rdfs:label "anemia" ;
  rdfs:comment "A hematopoietic system disease that is characterized by a decrease in the normal number of red blood cells." ;
  rdfs:subClassOf obo:DOID_74 .

obo:PATO_0000161 a rdfs:Class ;
  rdfs:label "rate" ;
  rdfs:comment "A quality of a single process inhering in a bearer by virtue of the bearer's occurrence per unit time." ;
  rdfs:subClassOf obo:PATO_0002062 .

obo:DOID_12510 a rdfs:Class ;
  rdfs:label "retinal ischemia" ;
  rdfs:subClassOf obo:DOID_5679 .

obo:IAO_0000015 a rdfs:Class ;
  rdfs:label "information carrier"@en ;
  rdfs:comment "A quality of an information bearer that imparts the information content"@en ;
  rdfs:subClassOf obo:BFO_0000019 .

obo:DOID_2527 a rdfs:Class ;
  rdfs:label "nephrosis" ;
  rdfs:subClassOf obo:DOID_557 .

obo:IAO_0000650 a rdfs:Class ;
  rdfs:label "database extract, transform, and load process"@en ;
  rdfs:comment "A planned process which takes as input a database and fills another database by extracting concretizations of information entities from the first, transforming them, and loading the transformed concretizations into the second."@en ;
  rdfs:subClassOf obo:OBI_0000011 .

obo:DOID_11465 a rdfs:Class ;
  rdfs:label "autonomic nervous system disease" ;
  rdfs:subClassOf obo:DOID_574 .

obo:OGMS_0000078 a rdfs:Class ;
  rdfs:label "pathological anatomical structure" ;
  rdfs:comment "An anatomical structure (FMA) is pathological whenever (1) it has come into being as a result of changes in some pre-existing canonical anatomical structure, (2) through processes other than the expression of the normal complement of genes of an organism of the given type, and (3) is predisposed to have health-related consequences for the organism in question manifested by symptoms and signs."@en ;
  rdfs:subClassOf obo:BFO_0000040 .

obo:OGMS_0000089 a rdfs:Class ;
  rdfs:label "congenital malformation" ;
  rdfs:comment "A structurally anomalous part of an organism acquired during fetal development and present at birth (but not necessarily hereditary) which is hypothesized to be harmful for the organism."@en ;
  rdfs:subClassOf obo:BFO_0000040 .

obo:IAO_0000321 a rdfs:Class ;
  rdfs:label "author list"@en ;
  rdfs:comment "part of a document that enumerates the authors of the document"@en ;
  rdfs:subClassOf obo:IAO_0000314 .

obo:IAO_0000429 a rdfs:Class ;
  rdfs:label "email address"@en ;
  rdfs:subClassOf obo:IAO_0000030 .

obo:DOID_874 a rdfs:Class ;
  rdfs:label "bacterial pneumonia" ;
  rdfs:comment "A pneumonia involving inflammation of the lungs caused by bacteria." ;
  rdfs:subClassOf obo:DOID_552 .

obo:OBI_0100026 a rdfs:Class ;
  rdfs:label "organism"@en ;
  rdfs:subClassOf obo:BFO_0000040 .

obo:IAO_0000574 a rdfs:Class ;
  rdfs:label "assigning a centrally registered identifier"@en ;
  rdfs:comment "a planned process in which a new CRID is created, associated with an entity, and stored in the CRID registry thereby registering it as being associated with some entity"@en ;
  rdfs:subClassOf obo:OBI_0000011 .

obo:OGMS_0000100 a rdfs:Class ;
  rdfs:label "inpatient encounter" ;
  rdfs:comment "TODO"@en ;
  rdfs:subClassOf obo:OGMS_0000097 .

obo:DOID_1920 a rdfs:Class ;
  rdfs:label "hyperuricemia" ;
  rdfs:comment "An acquired metabolic disease that has_material_basis_in an abnormally high level of uric acid in the blood." ;
  rdfs:subClassOf obo:DOID_0060158 .

obo:OGMS_0000029 a rdfs:Class ;
  rdfs:label "vital sign" ;
  rdfs:comment "A physical sign in which a non-zero value is standardly considered to be an indication that the organism is alive."@en ;
  rdfs:subClassOf obo:OGMS_0000024 .

obo:IAO_0000186 a rdfs:Class ;
  rdfs:label "photographic print"@en ;
  rdfs:comment "A photographic print is a material entity upon which a photograph generically depends."@en ;
  rdfs:subClassOf obo:BFO_0000040 , obo:IAO_0000178 .

obo:DOID_1579 a rdfs:Class ;
  rdfs:label "respiratory system disease" ;
  rdfs:comment "A disease of anatomical entity that located_in the respiratory system which extends from the nasal sinuses to the diaphragm." ;
  rdfs:subClassOf obo:DOID_7 .

obo:IAO_0000037 a rdfs:Class ;
  rdfs:label "dot plot"@en ;
  rdfs:comment "A dot plot is a report graph which is a graphical representation of data where each data point is represented by a single dot placed on coordinates corresponding to data point values in particular dimensions."@en ;
  rdfs:subClassOf obo:IAO_0000038 .

<http://purl.obolibrary.org/obo/http://purl.obolibrary.org/obo/VSO_0000027> a rdfs:Class ;
  rdfs:label "palpatory pulse rate measurement process"@en ;
  rdfs:subClassOf obo:VSO_0000031 .

obo:OGMS_0000031 a rdfs:Class ;
  rdfs:label "disease" ;
  rdfs:comment "A disposition (i) to undergo pathological processes that (ii) exists in an organism because of one or more disorders in that organism."@en ;
  rdfs:subClassOf obo:BFO_0000016 .

obo:IAO_0000181 a rdfs:Class ;
  rdfs:label "Venn diagram"@en ;
  rdfs:comment """A Venn diagram is a report graph showing all hypothetically possible
logical relations between a finite collection of sets."""@en ;
  rdfs:subClassOf obo:IAO_0000038 .

obo:IAO_0000101 a rdfs:Class ;
  rdfs:label "image"@en ;
  rdfs:comment "An image is an affine projection to a two dimensional surface, of measurements of some quality of an entity or entities repeated at regular intervals across a spatial range, where the measurements are represented as color and luminosity on the projected on surface."@en ;
  rdfs:subClassOf obo:IAO_0000308 .

obo:DOID_850 a rdfs:Class ;
  rdfs:label "lung disease" ;
  rdfs:comment "A lower respiratory tract disease in which the function of the lungs is adversely affected by narrowing or blockage of the airways resulting in poor air flow, a loss of elasticity in the lungs that produces a decrease in the total volume of air that the lungs are able to hold, and clotting, scarring, or inflammation of the blood vessels that affect the ability of the lungs to take up oxygen and to release carbon dioxide." ;
  rdfs:subClassOf obo:DOID_0050161 .

obo:VSO_0000012 a rdfs:Class ;
  rdfs:label "carotid pulse rate"@en ;
  rdfs:comment "The pulse rate of the carotid artery." ;
  rdfs:subClassOf obo:VSO_0000029 .

obo:DOID_720 a rdfs:Class ;
  rdfs:label "normocytic anemia" ;
  rdfs:subClassOf obo:DOID_2355 .

obo:DOID_2218 a rdfs:Class ;
  rdfs:label "blood platelet disease" ;
  rdfs:subClassOf obo:DOID_2213 .

obo:DOID_1074 a rdfs:Class ;
  rdfs:label "kidney failure" ;
  rdfs:comment "A kidney disease characterized by the failure of the kidneys to adequately filter waste products from the blood." ;
  rdfs:subClassOf obo:DOID_557 .

obo:OGMS_0000095 a rdfs:Class ;
  rdfs:label "inflammatory process" ;
  rdfs:comment "A bodily process caused by some disorder that results in recruitment of leukocytes into a localized tissue site, typically causing localized pain and swelling. "@en ;
  rdfs:subClassOf obo:OGMS_0000060 .

obo:DOID_962 a rdfs:Class ;
  rdfs:label "neurofibroma" ;
  rdfs:subClassOf obo:DOID_3193 .

obo:DOID_809 a rdfs:Class ;
  rdfs:label "cocaine abuse" ;
  rdfs:comment "A substance abuse that involves the recurring use of cocaine despite negative consequences." ;
  rdfs:subClassOf obo:DOID_302 .

obo:VSO_0000045 a rdfs:Class ;
  rdfs:label "tympanic temperature"@en ;
  rdfs:comment "The temperature of the external acoustic tube." ;
  rdfs:subClassOf obo:VSO_0000007 .

obo:DOID_5614 a rdfs:Class ;
  rdfs:label "eye disease" ;
  rdfs:comment "An eye and adnexa disease that is located_in the eye." ;
  rdfs:subClassOf obo:DOID_1492 .

obo:DOID_0050615 a rdfs:Class ;
  rdfs:label "respiratory system cancer" ;
  rdfs:comment "An organ system cancer located_in the respiratory system that is characterized by uncontrolled cellular proliferation in the respiratory tract." ;
  rdfs:subClassOf obo:DOID_0050686 .

obo:UO_0000001 a rdfs:Class ;
  rdfs:label "length unit" ;
  rdfs:comment "A unit which is a standard measure of the distance between two points." ;
  rdfs:subClassOf obo:IAO_0000003 .

obo:VSO_0000004 a rdfs:Class ;
  rdfs:label "blood pressure"@en ;
  rdfs:comment "The pressure exerted by circulating blood on the walls of blood vessels."@en ;
  rdfs:seeAlso <http://purl.bioontology.org/ontology/MDR/10005727> , <http://purl.bioontology.org/ontology/LNC/LP40259-1> , <http://purl.bioontology.org/ontology/SNOMEDCT/75367002> , <http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#Blood_Pressure> , <http://purl.bioontology.org/ontology/CMO/CMO_0000003> , <http://purl.bioontology.org/ontology/MSH/D001794> ;
  rdfs:subClassOf obo:OGMS_0000029 .

obo:PATO_0001236 a rdfs:Class ;
  rdfs:label "process quality" ;
  rdfs:subClassOf obo:BFO_0000019 .

obo:IAO_0000582 a rdfs:Class ;
  rdfs:label "time stamped measurement datum"@en ;
  rdfs:subClassOf obo:IAO_0000109 .

obo:IAO_0000583 a rdf:Property ;
  rdfs:label "has measurement datum"@en ;
  rdfs:comment "relates a time stamped measurement datum to the measurement datum that was measured"@en ;
  rdfs:domain obo:IAO_0000582 ;
  rdfs:range <https://w3id.org/linkml/Any> ;
  rdfs:subPropertyOf obo:BFO_0000051 .

obo:IAO_0000581 a rdf:Property ;
  rdfs:label "has time stamp"@en ;
  rdfs:comment "relates a time stamped measurement datum to the time measurement datum that denotes the time when the measurement was taken"@en ;
  rdfs:domain obo:IAO_0000582 ;
  rdfs:range obo:IAO_0000416 ;
  rdfs:subPropertyOf obo:BFO_0000051 .

obo:BFO_0000035 a rdfs:Class ;
  rdfs:label "process boundary"@en ;
  rdfs:comment "p is a process boundary =Def. p is a temporal part of a process & p has no proper temporal parts. (axiom label in BFO2 Reference: [084-001])"@en ;
  rdfs:subClassOf obo:BFO_0000003 .

obo:OGMS_0000018 a rdfs:Class ;
  rdfs:label "laboratory finding" ;
  rdfs:comment "A representation of a quality of a specimen that is the output of a laboratory test and that can support an inference to an assertion about some quality of the patient."@en ;
  rdfs:subClassOf obo:OGMS_0000014 .

obo:IAO_0000621 a rdfs:Class ;
  rdfs:label "ethical approval textual entity"@en ;
  rdfs:comment "A textual entity that documents the ethical approval of some study design."@en ;
  rdfs:subClassOf obo:IAO_0000300 .

obo:BFO_0000019 a rdfs:Class ;
  rdfs:label "quality" ;
  rdfs:subClassOf obo:BFO_0000020 .

obo:IAO_0000637 a rdfs:Class ;
  rdfs:label "pre-publication history section"@en ;
  rdfs:comment "A part of the document about the publication history of a document. This section typically details dates of document submission to a journal and dates of any re-submissions as well as reviewer comments and responses to reviewers by the authors."@en ;
  rdfs:subClassOf obo:IAO_0000314 .

obo:VSO_0000001 a rdfs:Class ;
  rdfs:label "auscultatory blood pressure measurement process"@en ;
  rdfs:subClassOf obo:VSO_0000024 .

obo:PATO_0000011 a rdfs:Class ;
  rdfs:label "age" ;
  rdfs:comment "A time quality inhering in a bearer by virtue of how long the bearer has existed." ;
  rdfs:subClassOf obo:PATO_0001237 .

obo:DOID_10908 a rdfs:Class ;
  rdfs:label "hydrocephalus" ;
  rdfs:comment "A cerebral degeneration characterized by an abnormal accumulation of cerebrospinal fluid in the ventricles of the brain, leading to progressive enlargement of the head." ;
  rdfs:subClassOf obo:DOID_1443 .

obo:DOID_6000 a rdfs:Class ;
  rdfs:label "congestive heart failure" ;
  rdfs:comment "A heart disease that is characterized by any structural or functional cardiac disorder that impairs the ability of the heart to fill with or pump a sufficient amount of blood throughout the body." ;
  rdfs:subClassOf obo:DOID_114 .

obo:VSO_0000034 a rdfs:Class ;
  rdfs:label "respiratory rate"@en ;
  rdfs:comment "The rate at which an organism breathes." ;
  rdfs:seeAlso <http://purl.bioontology.org/ontology/MDR/10038709> , <http://purl.bioontology.org/ontology/SNOMEDCT/86290005> , <http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#Respiratory_Rate> , <http://purl.bioontology.org/ontology/LNC/MTHU008344> , <http://www.co-ode.org/ontologies/galen#RespiratoryRate> , <http://purl.bioontology.org/ontology/CMO/CMO_0000289> , <http://purl.bioontology.org/ontology/MSH/D056152> ;
  rdfs:subClassOf obo:OGMS_0000029 , obo:PATO_0000161 .

obo:GO_0007599 a rdfs:Class ;
  rdfs:label "hemostasis" ;
  rdfs:subClassOf obo:GO_0050878 .

obo:DOID_1673 a rdfs:Class ;
  rdfs:label "pneumothorax" ;
  rdfs:subClassOf obo:DOID_1532 .

obo:DOID_0050871 a rdfs:Class ;
  rdfs:label "fibroma" ;
  rdfs:subClassOf obo:DOID_0060084 .

obo:DOID_2316 a rdfs:Class ;
  rdfs:label "brain ischemia" ;
  rdfs:subClassOf obo:DOID_326 .

obo:OGMS_0000064 a rdfs:Class ;
  rdfs:label "chronic disease course" ;
  rdfs:comment "A disease course that (a) does not terminate in a return to normal homeostasis and (b) would, absent intervention, fall within abnormal homeostatic range."@en ;
  rdfs:subClassOf obo:OGMS_0000063 .

obo:OGMS_0000096 a rdfs:Class ;
  rdfs:label "health care process" ;
  rdfs:comment "A planned process with the objective to improve the health status of a patient that directly involves the treatment, diagnosis, or prevention of disease or injury of a patient"@en ;
  rdfs:subClassOf obo:OBI_0000011 .

obo:IAO_0000632 a rdfs:Class ;
  rdfs:label "study limitations textual entity"@en ;
  rdfs:comment "A textual entity addressing a shortcoming or bias of a study design or execution."@en ;
  rdfs:subClassOf obo:IAO_0000300 .

obo:IAO_0000615 a rdfs:Class ;
  rdfs:label "conclusion section"@en ;
  rdfs:comment "A part of a document used to summarize the findings discussed in the document. The conclusion section is typically found near the end of a document. "@en ;
  rdfs:subClassOf obo:IAO_0000314 .

obo:IAO_0000025 a rdfs:Class ;
  rdfs:label "programming language"@en ;
  rdfs:comment "A language in which source code is written that is intended to be executed/run by a software interpreter. Programming languages are ways to write instructions that specify what to do, and sometimes, how to do it."@en ;
  rdfs:subClassOf obo:IAO_0000104 .

obo:IAO_0000643 a rdfs:Class ;
  rdfs:label "statistical analysis textual entity"@en ;
  rdfs:comment "A textual entity documenting statistical analysis tools and techniques employed."@en ;
  rdfs:subClassOf obo:IAO_0000300 .

obo:IAO_0000096 a rdfs:Class ;
  rdfs:label "source code module"@en ;
  rdfs:comment "A source code module is a directive information entity that specifies, using a programming language, some algorithm."@en ;
  rdfs:subClassOf obo:IAO_0000033 .

obo:VSO_0000016 a rdfs:Class ;
  rdfs:label "diastolic central venous pressure"@en ;
  rdfs:comment "The diastolic blood pressure in the thoracic vena cava." ;
  rdfs:subClassOf obo:VSO_0000015 .

obo:DOID_1875 a rdfs:Class ;
  rdfs:label "impotence" ;
  rdfs:subClassOf obo:DOID_1876 .

obo:DOID_3817 a rdfs:Class ;
  rdfs:label "cranial nerve palsy" ;
  rdfs:subClassOf obo:DOID_5656 .

obo:OGMS_0000103 a rdfs:Class ;
  rdfs:label "disease prophylaxis" ;
  rdfs:comment "A planned process whose completion is hypothesized by a health care provider to reduce the risk of developing a disorder or the signs and symptoms of a disorder."@en ;
  rdfs:subClassOf obo:OBI_0000011 .

obo:IAO_0000311 a rdfs:Class ;
  rdfs:label "publication"@en ;
  rdfs:comment "A document that has been accepted by a publisher"@en ;
  rdfs:subClassOf obo:IAO_0000310 .

obo:OGMS_0000025 a rdfs:Class ;
  rdfs:label "clinical manifestation of a disease" ;
  rdfs:comment "A manifestation of a disease that is detectable in a clinical history taking or physical examination."@en ;
  rdfs:subClassOf obo:OGMS_0000022 .

obo:OGMS_0000099 a rdfs:Class ;
  rdfs:label "outpatient encounter" ;
  rdfs:comment "TODO"@en ;
  rdfs:subClassOf obo:OGMS_0000097 .

obo:GO_0065008 a rdfs:Class ;
  rdfs:label "regulation of biological quality" ;
  rdfs:subClassOf obo:GO_0065007 .

obo:DOID_0050687 a rdfs:Class ;
  rdfs:label "cell type cancer" ;
  rdfs:comment "A cancer that is classified by the type of cell from which it is derived." ;
  rdfs:subClassOf obo:DOID_162 .

obo:IAO_0000144 a rdfs:Class ;
  rdfs:label "conclusion textual entity"@en ;
  rdfs:comment "A textual entity that expresses the results of reasoning about a problem, for instance as typically found towards the end of scientific papers."@en ;
  rdfs:subClassOf obo:IAO_0000300 .

obo:DOID_13223 a rdfs:Class ;
  rdfs:label "uterine fibroid" ;
  rdfs:comment "A uterine benign neoplasm derived from the smooth muscle layer of the uterus." ;
  rdfs:subClassOf obo:DOID_0050871 , obo:DOID_0060095 .

obo:VSO_0000029 a rdfs:Class ;
  rdfs:label "pulse rate"@en ;
  rdfs:comment "The rate at which an artery pulses (i.e., participates in expansion-contraction cycles) as blood passes through it."@en ;
  rdfs:seeAlso <http://purl.bioontology.org/ontology/MDR/10037485> , <http://purl.bioontology.org/ontology/SNOMEDCT/78564009> , <http://www.co-ode.org/ontologies/galen#Pulse> , <http://purl.bioontology.org/ontology/CMO/CMO_0000294> , <http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#Pulse_Rate> , <http://purl.bioontology.org/ontology/MSH/D006339> ;
  rdfs:subClassOf obo:OGMS_0000029 , obo:PATO_0000161 .

obo:DOID_870 a rdfs:Class ;
  rdfs:label "neuropathy" ;
  rdfs:comment "A nervous system disease that is located_in nerves or nerve cells." ;
  rdfs:subClassOf obo:DOID_574 .

obo:DOID_4556 a rdfs:Class ;
  rdfs:label "lung large cell carcinoma" ;
  rdfs:subClassOf obo:DOID_3908 , obo:DOID_4552 .

obo:DOID_4194 a rdfs:Class ;
  rdfs:label "glucose metabolism disease" ;
  rdfs:subClassOf obo:DOID_0050013 .

obo:IAO_0000591 a rdfs:Class ;
  rdfs:label "software method"@en ;
  rdfs:comment "A software method (also called subroutine, subprogram, procedure, method, function, or routine) is software designed to execute a specific task."@en ;
  rdfs:subClassOf obo:IAO_0000010 .

obo:OGMS_0000014 a rdfs:Class ;
  rdfs:label "clinical finding" ;
  rdfs:comment "A representation that is either the output of a clinical history taking or a physical examination or an image finding, or some combination thereof."@en ;
  rdfs:subClassOf obo:IAO_0000027 .

obo:BFO_0000020 a rdfs:Class ;
  rdfs:label "specifically dependent continuant"@en ;
  rdfs:comment "A continuant that inheres in or is borne by other entities. Every instance of A requires some specific instance of B which must always be the same."@en ;
  rdfs:subClassOf obo:BFO_0000002 .

obo:HTN_00000046 a rdfs:Class ;
  rdfs:label "stage 2 elevated adult diastolic blood pressure measurement datum per 2017 guidelines"@en ;
  rdfs:subClassOf obo:HTN_00000044 .

obo:DOID_10272 a rdfs:Class ;
  rdfs:label "left bundle branch hemiblock" ;
  rdfs:subClassOf obo:DOID_10273 .

obo:IAO_0000578 a rdfs:Class ;
  rdfs:label "centrally registered identifier"@en ;
  rdfs:comment "An information content entity that consists of a CRID symbol and additional information about the CRID registry to which it belongs."@en ;
  rdfs:subClassOf obo:IAO_0000030 .

obo:OGMS_0000086 a rdfs:Class ;
  rdfs:label "syndrome" ;
  rdfs:comment "A pattern of signs and symptoms that typically co-occur."@en ;
  rdfs:subClassOf obo:BFO_0000019 .

obo:OGMS_0000094 a rdfs:Class ;
  rdfs:label "acute disease course" ;
  rdfs:comment "a disease course with a rapid onset but typical unfolding of signs and symptoms after this rapid onset."@en ;
  rdfs:subClassOf obo:OGMS_0000063 .

obo:IAO_0000329 a rdfs:Class ;
  rdfs:label "running title"@en ;
  rdfs:comment "A shorter version of a document title"@en ;
  rdfs:subClassOf obo:IAO_0000305 .

obo:IAO_0000185 a rdfs:Class ;
  rdfs:label "photograph"@en ;
  rdfs:comment "A photograph is created by projecting an image onto a photosensitive surface such as a chemically treated plate or film, CCD receptor, etc."@en ;
  rdfs:subClassOf obo:IAO_0000101 .

obo:DOID_0050152 a rdfs:Class ;
  rdfs:label "aspiration pneumonia" ;
  rdfs:comment "A bacterial pneumonia which is an acute pulmonary inflammatory response that develops after the inhalation of colonized oropharyngeal material containing bacteria. It is seen in individuals with dysphagia and gastric dysmotility. The disease has_symptom tachypnea and has_symptom cough." ;
  rdfs:subClassOf obo:DOID_874 .

obo:OBI_0000066 a rdfs:Class ;
  rdfs:label "investigation"@en ;
  rdfs:comment "a planned process that consists of parts: planning, study design execution, documentation and which produce conclusion(s)."@en ;
  rdfs:subClassOf obo:OBI_0000011 .

obo:DOID_0050622 a rdfs:Class ;
  rdfs:label "reproductive organ benign neoplasm" ;
  rdfs:comment "An organ system benign neoplasm that is located_in reproductive system organs." ;
  rdfs:subClassOf obo:DOID_0060085 .

obo:DOID_5679 a rdfs:Class ;
  rdfs:label "retinal disease" ;
  rdfs:comment "An eye disease that is located_in the retina." ;
  rdfs:subClassOf obo:DOID_5614 .

<https://raw.githubusercontent.com/aellenhicks/htn_owl/master/htn.owl/_:genid12144> a rdfs:Class .

obo:BFO_0000086 a rdf:Property ;
  rdfs:domain <https://raw.githubusercontent.com/aellenhicks/htn_owl/master/htn.owl/_:genid12144> ;
  rdfs:range xsd:string .

obo:DOID_2741 a rdfs:Class ;
  rdfs:label "bilirubin metabolic disorder" ;
  rdfs:comment "An inherited metabolic disorder that involves elevated levels of bilirubin resulting from disruption of bilirubin metabolism." ;
  rdfs:subClassOf obo:DOID_655 .

obo:IAO_0000626 a rdfs:Class ;
  rdfs:label "future directions textual entity"@en ;
  rdfs:comment "A textual entity expressing ideas regarding future work relevant to work described in a document that could be done."@en ;
  rdfs:subClassOf obo:IAO_0000300 .

obo:IAO_0000619 a rdfs:Class ;
  rdfs:label "consent textual entity"@en ;
  rdfs:comment "A textual entity that documents the consenting process used to enroll patients in a study."@en ;
  rdfs:subClassOf obo:IAO_0000300 .

obo:DOID_13094 a rdfs:Class ;
  rdfs:label "branch retinal artery occlusion" ;
  rdfs:subClassOf obo:DOID_8483 .

obo:DOID_936 a rdfs:Class ;
  rdfs:label "brain disease" ;
  rdfs:comment "A central nervous system disease that is located_in the brain." ;
  rdfs:subClassOf obo:DOID_331 .

obo:IAO_0000079 a rdfs:Class ;
  rdfs:label "density plot"@en ;
  rdfs:comment "A density plot is a report graph which is a graphical representation of data where the tint of a particular pixel corresponds to some kind of function corresponding the the amount of data points relativelly with their distance from the the pixel."@en ;
  rdfs:subClassOf obo:IAO_0000038 .

obo:DOID_2348 a rdfs:Class ;
  rdfs:label "arteriosclerotic cardiovascular disease" ;
  rdfs:subClassOf obo:DOID_2349 .

obo:DOID_7 a rdfs:Class ;
  rdfs:label "disease of anatomical entity" ;
  rdfs:comment "A disease that manifests in a defined anatomical structure." ;
  rdfs:subClassOf obo:OGMS_0000031 .

obo:PATO_0000396 a rdfs:Class ;
  rdfs:label "severe intensity" ;
  rdfs:subClassOf obo:PATO_0000049 .

obo:DOID_4552 a rdfs:Class ;
  rdfs:label "large cell carcinoma" ;
  rdfs:comment "A carcinoma that is composed of large, monotonous rounded or overtly polygonal-shaped cells with abundant cytoplasm." ;
  rdfs:subClassOf obo:DOID_305 .

obo:DOID_11516 a rdfs:Class ;
  rdfs:label "hypertensive heart disease" ;
  rdfs:comment "A heart disease that is caused by high blood pressure." ;
  rdfs:subClassOf obo:DOID_114 .

obo:OGMS_0000020 a rdfs:Class ;
  rdfs:label "symptom" ;
  rdfs:comment "A quality of a patient that is observed by the patient or a processual entity experienced by the patient, either of which is hypothesized by the patient to be a realization of a disease."@en ;
  rdfs:subClassOf obo:BFO_0000001 .

obo:VSO_0000018 a rdfs:Class ;
  rdfs:label "diastolic pulmonary artery pressure"@en ;
  rdfs:comment "The pulmonary artery pressure during diastole." ;
  rdfs:subClassOf obo:VSO_0000015 .

obo:OBI_0000245 a rdfs:Class ;
  rdfs:label "organization"@en ;
  rdfs:subClassOf obo:BFO_0000040 .

obo:DOID_2452 a rdfs:Class ;
  rdfs:label "thrombophilia" ;
  rdfs:comment "OMIM mapping confirmed by DO. [LS]." ;
  rdfs:subClassOf obo:DOID_1247 .

obo:IAO_0000003 a rdfs:Class ;
  rdfs:label "measurement unit label"@en ;
  rdfs:comment "A measurement unit label is as a label that is part of a scalar measurement datum and denotes a unit of measure."@en ;
  rdfs:subClassOf obo:IAO_0000009 .

obo:DOID_780 a rdfs:Class ;
  rdfs:label "placenta disease" ;
  rdfs:comment "A uterine disease that is located_in the placenta." ;
  rdfs:subClassOf obo:DOID_345 .

obo:IAO_0000109 a rdfs:Class ;
  rdfs:label "measurement datum"@en ;
  rdfs:comment "A measurement datum is an information content entity that is a recording of the output of a measurement such as produced by a device."@en ;
  rdfs:subClassOf obo:IAO_0000027 .

obo:DOID_0060036 a rdfs:Class ;
  rdfs:label "intrinsic cardiomyopathy" ;
  rdfs:comment "A cardiomyopathy that is characterized as weakness in the muscle of the heart that is not due to an identifiable external cause." ;
  rdfs:subClassOf obo:DOID_0050700 .

obo:IAO_0000305 a rdfs:Class ;
  rdfs:label "document title"@en ;
  rdfs:comment "A textual entity that names a document"@en ;
  rdfs:subClassOf obo:IAO_0000300 .

obo:OGMS_0000047 a rdfs:Class ;
  rdfs:label "genetic disorder" ;
  rdfs:comment "A disorder whose etiology involves an abnormality in the nucleotide sequence of an organism's genome."@en ;
  rdfs:subClassOf obo:OGMS_0000045 .

obo:DOID_9042 a rdfs:Class ;
  rdfs:label "polyp of corpus uteri" ;
  rdfs:subClassOf obo:DOID_345 .

obo:DOID_3146 a rdfs:Class ;
  rdfs:label "lipid metabolism disorder" ;
  rdfs:comment "An inherited metabolic disorder that involves the creation and degradation of lipids." ;
  rdfs:subClassOf obo:DOID_655 .

obo:OGMS_0000107 a rdfs:Class ;
  rdfs:label "ancillary health care process" ;
  rdfs:comment """A planned process that has the objective to support the objective of a health care process without directly involving the treatment, diagnosis, or prevention of disease or injury of a patient.
""" ;
  rdfs:subClassOf obo:OBI_0000011 .

obo:DOID_557 a rdfs:Class ;
  rdfs:label "kidney disease" ;
  rdfs:comment "A urinary system disease that is located_in the kidney." ;
  rdfs:subClassOf obo:DOID_18 .

obo:IAO_0000608 a rdfs:Class ;
  rdfs:label "author information textual entity"@en ;
  rdfs:comment "A textual entity expression information about an author of a document. This information may include biographical information and may discuss how the authors' professional experiences are relevant to the work described in the document."@en ;
  rdfs:subClassOf obo:IAO_0000300 .

obo:DOID_13148 a rdfs:Class ;
  rdfs:label "acute cystitis" ;
  rdfs:comment "A cystitis characterized by a sudden onset or severe symptoms." ;
  rdfs:subClassOf obo:DOID_1679 .

obo:GO_0085031 a rdfs:Class ;
  rdfs:label "commensalism" ;
  rdfs:subClassOf obo:GO_0044403 .

obo:PATO_0001199 a rdfs:Class ;
  rdfs:label "linear" ;
  rdfs:subClassOf obo:PATO_0000052 .

obo:VSO_0000007 a rdfs:Class ;
  rdfs:label "body temperature"@en ;
  rdfs:comment "The temperature of a part of the human body"@en ;
  rdfs:seeAlso <http://purl.bioontology.org/ontology/MDR/10005906> , <http://purl.bioontology.org/ontology/SNOMEDCT/386725007> , <http://purl.bioontology.org/ontology/LNC/LP29701-7> , <http://purl.bioontology.org/ontology/CMO/CMO_0000015> , <http://purl.bioontology.org/ontology/MSH/D001831> ;
  rdfs:subClassOf obo:OGMS_0000029 .

obo:DOID_2983 a rdfs:Class ;
  rdfs:label "anuria" ;
  rdfs:subClassOf obo:DOID_557 .

obo:HTN_00000015 a rdfs:Class ;
  rdfs:label "elevated blood pressure measurement datum"@en ;
  rdfs:comment "A blood pressure measurement datum with a measurement value that is equal to or above some specified threshold"@en ;
  rdfs:subClassOf obo:VSO_0000005 .

obo:DOID_326 a rdfs:Class ;
  rdfs:label "ischemia" ;
  rdfs:comment "A vascular disease that is characterized by a restriction in blood supply to tissues." ;
  rdfs:subClassOf obo:DOID_178 .

obo:IAO_0000038 a rdfs:Class ;
  rdfs:label "graph"@en ;
  rdfs:comment "A diagram that presents one or more tuples of information by mapping those tuples in to a two dimensional space in a non arbitrary way."@en ;
  rdfs:subClassOf obo:IAO_0000309 .

obo:DOID_0060072 a rdfs:Class ;
  rdfs:label "benign neoplasm" ;
  rdfs:comment "A disease of cellular proliferation that results in abnormal growths in the body which lack the ability to metastasize." ;
  rdfs:subClassOf obo:DOID_14566 .

obo:IAO_0000102 a rdfs:Class ;
  rdfs:label "data about an ontology part"@en ;
  rdfs:comment "data about an ontology part is a data item about a part of an ontology, for example a term"@en ;
  rdfs:subClassOf obo:IAO_0000027 .

obo:DOID_11247 a rdfs:Class ;
  rdfs:label "disseminated intravascular coagulation" ;
  rdfs:subClassOf obo:DOID_2452 .

obo:RO_0002577 a rdfs:Class ;
  rdfs:label "system" ;
  rdfs:comment "A material entity consisting of multiple components that are causally integrated." ;
  rdfs:subClassOf obo:BFO_0000040 .

obo:OGMS_0000063 a rdfs:Class ;
  rdfs:label "disease course" ;
  rdfs:comment "The totality of all processes through which a given disease instance is realized."@en ;
  rdfs:subClassOf obo:BFO_0000015 .

obo:PATO_0000057 a rdfs:Class ;
  rdfs:label "occurrence" ;
  rdfs:subClassOf obo:PATO_0002323 .

obo:OGMS_0000088 a rdfs:Class ;
  rdfs:label "patient symptom report" ;
  rdfs:comment "A communication from a patient about something they perceive as being abnormal about their body or life."@en ;
  rdfs:subClassOf obo:IAO_0000030 .

obo:IAO_0000575 a rdfs:Class ;
  rdfs:label "associating information with a centrally registered identifier in its registry"@en ;
  rdfs:comment "A planned process in which a CRID registry associates an information content entity with a CRID symbol"@en ;
  rdfs:subClassOf obo:OBI_0000011 .

obo:DOID_2744 a rdfs:Class ;
  rdfs:label "pyelitis" ;
  rdfs:subClassOf obo:DOID_557 .

obo:DOID_11561 a rdfs:Class ;
  rdfs:label "hypertensive retinopathy" ;
  rdfs:subClassOf obo:DOID_5679 .

obo:PATO_0000068 a rdfs:Class ;
  rdfs:label "qualitative" ;
  rdfs:subClassOf obo:BFO_0000019 .

obo:VSO_0000037 a rdfs:Class ;
  rdfs:label "systole"@en ;
  rdfs:comment "The phase of the cardiac cycle in which the heart contracts." ;
  rdfs:subClassOf obo:VSO_0000011 .

obo:OGMS_0000023 a rdfs:Class ;
  rdfs:label "phenotype" ;
  rdfs:comment "A (combination of) quality(ies) of an organism determined by the interaction of its genetic make-up and environment that differentiates specific instances of a species from other instances of the same species."@en ;
  rdfs:subClassOf obo:BFO_0000019 .

obo:GO_0006950 a rdfs:Class ;
  rdfs:label "response to stress" ;
  rdfs:subClassOf obo:GO_0050896 .

obo:VSO_0000003 a rdfs:Class ;
  rdfs:label "axillary temperature"@en ;
  rdfs:comment "The temperature of the axillary fossa." ;
  rdfs:subClassOf obo:VSO_0000007 .

obo:IAO_0000638 a rdfs:Class ;
  rdfs:label "pre-publication history textual entity"@en ;
  rdfs:comment "A textual entity that expresses the pre-publication history (submission dates, reviewer comments, etc) for a document, often including a hyperlink to a web page detailing the information."@en ;
  rdfs:subClassOf obo:IAO_0000300 .

obo:GO_0007596 a rdfs:Class ;
  rdfs:label "blood coagulation" ;
  rdfs:subClassOf obo:GO_0007599 , obo:GO_0050817 .

obo:DOID_10944 a rdfs:Class ;
  rdfs:label "tongue disease" ;
  rdfs:subClassOf obo:DOID_403 .

obo:IAO_0000010 a rdfs:Class ;
  rdfs:label "software"@en ;
  rdfs:comment """Software is a plan specification composed of a series of instructions that can be 
interpreted by or directly executed by a processing unit."""@en ;
  rdfs:subClassOf obo:IAO_0000104 .

obo:OGMS_0000077 a rdfs:Class ;
  rdfs:label "pathological formation" ;
  rdfs:comment "TODO: Define, relate to disorder, and place in the OGMS hierarchy."@en ;
  rdfs:subClassOf obo:BFO_0000040 .

obo:IAO_0000032 a rdfs:Class ;
  rdfs:label "scalar measurement datum"@en ;
  rdfs:comment "a scalar measurement datum is a measurement datum that is composed of two parts, numerals and a unit label."@en ;
  rdfs:subClassOf obo:IAO_0000109 .

obo:IAO_0000605 a rdfs:Class ;
  rdfs:label "abbreviation textual entity"@en ;
  rdfs:comment "A textual entity listing abbreviations and their expansions that are used in a document."@en ;
  rdfs:subClassOf obo:IAO_0000300 .

obo:ENVO_01000254 a rdfs:Class ;
  rdfs:label "environmental system" ;
  rdfs:subClassOf obo:RO_0002577 .

obo:DOID_0050013 a rdfs:Class ;
  rdfs:label "carbohydrate metabolism disease" ;
  rdfs:comment "An acquired metabolic disease that is characterized by abnormal carbohydrate metabolism." ;
  rdfs:subClassOf obo:DOID_0060158 .

obo:HTN_00000006 a rdfs:Class ;
  rdfs:label "elevated systolic phenotype"@en ;
  rdfs:comment "An elevated blood pressure phenotype of systolic blood pressure that is above some specifed threshold" ;
  rdfs:subClassOf obo:HTN_00000014 .

obo:IAO_0000624 a rdfs:Class ;
  rdfs:label "funding source declaration textual entity"@en ;
  rdfs:comment "A textual entity documenting the source of funding that supported some study."@en ;
  rdfs:subClassOf obo:IAO_0000300 .

obo:IAO_0000034 a rdfs:Class ;
  rdfs:label "time trigger"@en ;
  rdfs:comment "revisit?"@en ;
  rdfs:subClassOf obo:IAO_0000001 .

obo:OGMS_0000055 a rdfs:Class ;
  rdfs:label "clinical history taking" ;
  rdfs:comment "A health care process in which a clinician elicits a description of previous sign and symptoms of disease from a patient or from a third party who is reporting on behalf of the patient."@en ;
  rdfs:subClassOf obo:OGMS_0000108 .

obo:IAO_0000631 a rdfs:Class ;
  rdfs:label "study limitations section"@en ;
  rdfs:comment "A part of a document about biases or short comings related to the study design and execution."@en ;
  rdfs:subClassOf obo:IAO_0000314 .

obo:PATO_0001874 a rdfs:Class ;
  rdfs:label "discoid" ;
  rdfs:subClassOf obo:PATO_0001873 .

obo:DOID_1168 a rdfs:Class ;
  rdfs:label "familial hyperlipidemia" ;
  rdfs:subClassOf obo:DOID_3146 .

obo:DOID_3193 a rdfs:Class ;
  rdfs:label "peripheral nerve sheath neoplasm" ;
  rdfs:comment "A peripheral nervous system neoplasm that is located_in the connective tissue surrounding nerves." ;
  rdfs:subClassOf obo:DOID_1192 .

obo:PATO_0000049 a rdfs:Class ;
  rdfs:label "intensity" ;
  rdfs:subClassOf obo:PATO_0000068 .

obo:HTN_00000035 a rdfs:Class ;
  rdfs:label "diagnosis of hypertension"@en ;
  rdfs:comment "A diagnosis that asserts of some patient that they have a disposition to chronically elevated blood pressure" ;
  rdfs:subClassOf obo:OGMS_0000073 .

obo:OGMS_0000083 a rdfs:Class ;
  rdfs:label "physical examination finding" ;
  rdfs:comment "TODO: Define."@en ;
  rdfs:subClassOf obo:OGMS_0000014 .

obo:DOID_1287 a rdfs:Class ;
  rdfs:label "cardiovascular system disease" ;
  rdfs:comment "A disease of anatomical entity which occurs in the blood, heart, blood vessels or the lymphatic system that passes nutrients (such as amino acids and electrolytes), gases, hormones, blood cells or lymph to and from cells in the body to help fight diseases and help stabilize body temperature and pH to maintain homeostasis." ;
  rdfs:subClassOf obo:DOID_7 .

obo:BFO_0000148 a rdfs:Class ;
  rdfs:label "zero-dimensional temporal region"@en ;
  rdfs:subClassOf obo:BFO_0000008 .

obo:VSO_0000022 a rdfs:Class ;
  rdfs:label "femoral pulse rate"@en ;
  rdfs:comment "The pulse rate of the femoral artery." ;
  rdfs:subClassOf obo:VSO_0000029 .

obo:IAO_0000613 a rdfs:Class ;
  rdfs:label "case report section"@en ;
  rdfs:comment "A part of a document about the medical history of a specific patient as it relates to the topic of the document."@en ;
  rdfs:subClassOf obo:IAO_0000314 .

obo:IAO_0000322 a rdfs:Class ;
  rdfs:label "institution list"@en ;
  rdfs:comment "part of a document that has parts that are institution identifications associated with the authors of the document"@en ;
  rdfs:subClassOf obo:IAO_0000314 .

obo:VSO_0000033 a rdfs:Class ;
  rdfs:label "rectal temperature"@en ;
  rdfs:comment "The temperature of the lumen of the rectum." ;
  rdfs:subClassOf obo:VSO_0000007 .

obo:PATO_0002304 a rdfs:Class ;
  rdfs:label "increased process quality" ;
  rdfs:subClassOf obo:PATO_0001236 , obo:PATO_0002300 .

obo:OGMS_0000085 a rdfs:Class ;
  rdfs:label "pain" ;
  rdfs:comment "A bodily process in an organism S involving two integrated levels: (a) activation of the nociceptive system and associated emotion generating brain components of S, and (b) a simultaneous aversive sensory and emotional experience on the part of S, where (b) is phenomenologically similar to the sort of aversive experience involved in pain with concordant tissue damage."@en ;
  rdfs:subClassOf obo:OGMS_0000020 .

obo:DOID_3908 a rdfs:Class ;
  rdfs:label "non-small cell lung carcinoma" ;
  rdfs:comment "A lung carcinoma that is characterized as any type of epithelial lung cancer other than small cell lung carcinoma." ;
  rdfs:subClassOf obo:DOID_3905 .

obo:PATO_0000125 a rdfs:Class ;
  rdfs:label "mass" ;
  rdfs:comment "A physical quality that inheres in a bearer by virtue of the proportion of the bearer's amount of matter." ;
  rdfs:subClassOf obo:BFO_0000019 .

obo:IAO_0000300 a rdfs:Class ;
  rdfs:label "textual entity"@en ;
  rdfs:comment "A textual entity is a part of a manifestation (FRBR sense), a generically dependent continuant whose concretizations are patterns of glyphs intended to be interpreted as words, formulas, etc."@en ;
  rdfs:subClassOf obo:IAO_0000030 .

obo:BFO_0000003 a rdfs:Class ;
  rdfs:label "occurrent"@en ;
  rdfs:comment """
An entity that has temporal parts and that happens, unfolds or develops through time.
"""@en ;
  rdfs:subClassOf obo:BFO_0000001 .

obo:OGMS_0000034 a rdfs:Class ;
  rdfs:label "acquired genetic disease" ;
  rdfs:comment "A disease whose physical basis is an acquired genetic disorder."@en ;
  rdfs:subClassOf obo:OGMS_0000031 .

obo:IAO_0000595 a rdfs:Class ;
  rdfs:label "software script"@en ;
  rdfs:comment """ A software script is software whose instructions can be executed using a software 
interpreter."""@en ;
  rdfs:subClassOf obo:IAO_0000010 .

obo:VSO_0000011 a rdfs:Class ;
  rdfs:label "cardiac cycle phase"@en ;
  rdfs:subClassOf obo:GO_0008150 .

obo:IAO_0000642 a rdfs:Class ;
  rdfs:label "requirements textual entity"@en ;
  rdfs:comment "A textual entity that expresses the requirements necessary to use a resource, e.g. software."@en ;
  rdfs:subClassOf obo:IAO_0000300 .

obo:OGMS_0000045 a rdfs:Class ;
  rdfs:label "disorder" ;
  rdfs:comment "A material entity which is clinically abnormal and part of an extended organism. Disorders are the physical basis of disease."@en ;
  rdfs:subClassOf obo:BFO_0000040 .

obo:VSO_0000044 a rdfs:Class ;
  rdfs:label "tibialis posterior pulse rate"@en ;
  rdfs:comment "The pulse rate of the tibialis posterior artery." ;
  rdfs:subClassOf obo:VSO_0000029 .

obo:BFO_0000018 a rdfs:Class ;
  rdfs:label "zero-dimensional spatial region"@en ;
  rdfs:subClassOf obo:BFO_0000006 .

obo:DOID_0050851 a rdfs:Class ;
  rdfs:label "glomerulosclerosis" ;
  rdfs:comment "A glomerulonephritis that is characterized by hardening of the glomerulus in the kidney." ;
  rdfs:subClassOf obo:DOID_2921 .

obo:IAO_0000318 a rdfs:Class ;
  rdfs:label "results section"@en ;
  rdfs:comment "A part of a publication about an investigation that is about a study design execution"@en ;
  rdfs:subClassOf obo:IAO_0000314 .

obo:OGMS_0000097 a rdfs:Class ;
  rdfs:label "health care encounter" ;
  rdfs:comment "A temporally-connected health care process that has as participants an organization or person realizing the health care provider role and a person realizing the patient role.  The health care provider role and patient are realized during the health care encounter"@en ;
  rdfs:subClassOf obo:OGMS_0000096 .

obo:OGMS_0000066 a rdfs:Class ;
  rdfs:label "transient disease course" ;
  rdfs:comment "A disease course that terminates in a return to normal homeostasis."@en ;
  rdfs:subClassOf obo:OGMS_0000063 .

obo:DOID_365 a rdfs:Class ;
  rdfs:label "bladder disease" ;
  rdfs:comment "A urinary system disease that is located_in the bladder." ;
  rdfs:subClassOf obo:DOID_18 .

obo:OGMS_0000074 a rdfs:Class ;
  rdfs:label "normal value" ;
  rdfs:comment "A value for a quality reported in a lab report and asserted by the testing lab or the kit manufacturer to be normal based on a statistical treatment of values from a reference population."@en ;
  rdfs:subClassOf obo:BFO_0000031 .

obo:HTN_00000048 a rdfs:Class ;
  rdfs:label "elevated adult blood pressure measurement datum per 2017 guidelines"@en ;
  rdfs:comment "120–129 mm Hg and <80 mm Hg" ;
  rdfs:subClassOf obo:HTN_00000015 .

obo:HTN_00000000 a rdfs:Class ;
  rdfs:label "diastolic blood pressure measurement datum"@en ;
  rdfs:comment "A blood pressure measurement datum that is a quality measure of some diastolic blood pressure" ;
  rdfs:subClassOf obo:VSO_0000005 .

obo:PATO_0002007 a rdfs:Class ;
  rdfs:label "convex 3-D shape" ;
  rdfs:subClassOf obo:PATO_0002266 .

obo:PATO_0002124 a rdfs:Class ;
  rdfs:label "laminar" ;
  rdfs:subClassOf obo:PATO_0000141 .

obo:GO_0051850 a rdfs:Class ;
  rdfs:label "acquisition of nutrients from symbiont" ;
  rdfs:subClassOf obo:GO_0051702 , obo:GO_0051705 , obo:GO_0051816 .

obo:IAO_0000408 a rdfs:Class ;
  rdfs:label "length measurement datum"@en ;
  rdfs:comment "A scalar measurement datum that is the result of measurement of length quality"@en ;
  rdfs:subClassOf obo:IAO_0000032 .

obo:IAO_0000590 a rdfs:Class ;
  rdfs:label "written name"@en ;
  rdfs:comment "A textual entity that denotes a particular in reality."@en ;
  rdfs:subClassOf obo:IAO_0000300 .

obo:PATO_0000146 a rdfs:Class ;
  rdfs:label "temperature"@en ;
  rdfs:comment "A physical quality of the thermal energy of a system." ;
  rdfs:subClassOf obo:BFO_0000019 .

obo:DOID_620 a rdfs:Class ;
  rdfs:label "blood protein disease" ;
  rdfs:subClassOf obo:DOID_74 .

obo:IAO_0000065 a rdfs:Class ;
  rdfs:label "software interpreter"@en ;
  rdfs:comment "A software interpreter is a software application that executes some specified input software. "@en ;
  rdfs:subClassOf obo:IAO_0000064 .

obo:DOID_0050700 a rdfs:Class ;
  rdfs:label "cardiomyopathy" ;
  rdfs:comment "A heart disease and a myopathy that is characterized by deterioration of the function of the heart muscle." ;
  rdfs:subClassOf obo:DOID_114 .

obo:PATO_0001873 a rdfs:Class ;
  rdfs:label "cylindrical" ;
  rdfs:subClassOf obo:PATO_0002007 .

obo:IAO_0000307 a rdfs:Class ;
  rdfs:label "table of abbreviations"@en ;
  rdfs:comment "A table where the constituent texts are abbreviations and their expansions"@en ;
  rdfs:subClassOf obo:IAO_0000306 .

obo:DOID_303 a rdfs:Class ;
  rdfs:label "substance-related disorder" ;
  rdfs:comment "A disease of mental health involving the abuse or dependence on a substance that is ingested in order to produce a high, alter one's senses, or otherwise affect functioning." ;
  rdfs:subClassOf obo:DOID_150 .

obo:DOID_10825 a rdfs:Class ;
  rdfs:label "essential hypertension" ;
  rdfs:comment "A hypertension with no known cause. It is the most common type of hypertension." ;
  rdfs:subClassOf obo:DOID_10763 .

obo:GO_0050817 a rdfs:Class ;
  rdfs:label "coagulation" ;
  rdfs:subClassOf obo:GO_0032501 .

obo:BFO_0000140 a rdfs:Class ;
  rdfs:label "continuant fiat boundary"@en ;
  rdfs:comment "b is a continuant fiat boundary = Def. b is an immaterial entity that is of zero, one or two dimensions and does not include a spatial region as part. (axiom label in BFO2 Reference: [029-001])"@en ;
  rdfs:subClassOf obo:BFO_0000141 .

<https://raw.githubusercontent.com/aellenhicks/htn_owl/master/htn.owl/_:genid12168> a rdfs:Class .

obo:BFO_0000161 a rdf:Property ;
  rdfs:domain <https://raw.githubusercontent.com/aellenhicks/htn_owl/master/htn.owl/_:genid12168> ;
  rdfs:range xsd:string .

obo:UO_0000002 a rdfs:Class ;
  rdfs:label "mass unit" ;
  rdfs:comment "A unit which is a standard measure of the amount of matter/energy of a physical object." ;
  rdfs:subClassOf obo:IAO_0000003 .

obo:PATO_0000141 a rdfs:Class ;
  rdfs:label "structure" ;
  rdfs:subClassOf obo:PATO_0000051 .

obo:IAO_0000627 a rdfs:Class ;
  rdfs:label "genome announcement section"@en ;
  rdfs:comment "A document part announcing the publication of a novel draft genome sequence."@en ;
  rdfs:subClassOf obo:IAO_0000314 .

obo:IAO_0000057 a rdfs:Class ;
  rdfs:label "contour plot"@en ;
  rdfs:subClassOf obo:IAO_0000038 .

obo:DOID_10273 a rdfs:Class ;
  rdfs:label "heart conduction disease" ;
  rdfs:comment "A cardiovascular system disease that involves the heart's electrical conduction system." ;
  rdfs:subClassOf obo:DOID_114 .

<https://raw.githubusercontent.com/aellenhicks/htn_owl/master/htn.owl/_:genid12148> a rdfs:Class .

obo:BFO_0000087 a rdf:Property ;
  rdfs:domain <https://raw.githubusercontent.com/aellenhicks/htn_owl/master/htn.owl/_:genid12148> ;
  rdfs:range xsd:string .

obo:OGMS_0000080 a rdfs:Class ;
  rdfs:label "pathological transformation" ;
  rdfs:comment "A pathological bodily process in which a canonical anatomical structure becomes a pathological anatomical structure."@en ;
  rdfs:subClassOf obo:OGMS_0000061 .

obo:VSO_0000026 a rdfs:Class ;
  rdfs:label "oscillometric blood pressure measurement process"@en ;
  rdfs:subClassOf obo:VSO_0000024 .

obo:OGMS_0000056 a rdfs:Class ;
  rdfs:label "laboratory test" ;
  rdfs:comment "A measurement assay that has as input a patient-derived specimen and as output a data itme that is about a quality of the specimen."@en ;
  rdfs:subClassOf obo:OGMS_0000108 .

obo:GO_0050896 a rdfs:Class ;
  rdfs:label "response to stimulus" ;
  rdfs:subClassOf obo:GO_0008150 .

obo:GO_0051705 a rdfs:Class ;
  rdfs:label "multi-organism behavior" ;
  rdfs:subClassOf obo:GO_0007610 , obo:GO_0051704 .

obo:HTN_00000016 a rdfs:Class ;
  rdfs:label "elevated diastolic phenotype"@en ;
  rdfs:comment "An elevated blood pressure phenotype of diastolic blood pressure that is above some specifed threshold"@en ;
  rdfs:subClassOf obo:HTN_00000014 .

obo:IAO_0000620 a rdfs:Class ;
  rdfs:label "ethical approval section"@en ;
  rdfs:comment "A part of a document about the governance body responsible for approving the work discussed in a document on an ethical basis."@en ;
  rdfs:subClassOf obo:IAO_0000314 .

obo:DOID_0050828 a rdfs:Class ;
  rdfs:label "artery disease" ;
  rdfs:comment "A vascular disease that is located_in an artery." ;
  rdfs:subClassOf obo:DOID_178 .

obo:DOID_9351 a rdfs:Class ;
  rdfs:label "diabetes mellitus" ;
  rdfs:comment "A glucose metabolism disease characterized  by chronic hyperglycaemia with disturbances of carbohydrate, fat and protein metabolism resulting from defects in insulin secretion, insulin action, or both." ;
  rdfs:subClassOf obo:DOID_4194 .

obo:DOID_10591 a rdfs:Class ;
  rdfs:label "pre-eclampsia" ;
  rdfs:comment "A hypertension occurring during pregnancy characterized by large amounts of protein in the urine (proteinuria) and edema, usually by the last trimester of pregnancy." ;
  rdfs:subClassOf obo:DOID_10763 .

obo:IAO_0000140 a rdfs:Class ;
  rdfs:label "setting datum"@en ;
  rdfs:comment "A settings datum is a datum that denotes some configuration of an instrument."@en ;
  rdfs:subClassOf obo:IAO_0000027 .

obo:DOID_1247 a rdfs:Class ;
  rdfs:label "blood coagulation disease" ;
  rdfs:subClassOf obo:DOID_74 .

obo:OGMS_0000106 a rdfs:Class ;
  rdfs:label "remission"@en ;
  rdfs:comment "a disease stage which is characterized by the lack of a manifestation of a disease." ;
  rdfs:subClassOf <http://purl.obolibrary.org/obo/ogms.owl#disease_stage> .

obo:GO_0065007 a rdfs:Class ;
  rdfs:label "biological regulation" ;
  rdfs:subClassOf obo:GO_0008150 .

obo:DOID_784 a rdfs:Class ;
  rdfs:label "chronic kidney disease" ;
  rdfs:subClassOf obo:DOID_1074 .

obo:VSO_0000015 a rdfs:Class ;
  rdfs:label "diastolic blood pressure"@en ;
  rdfs:comment "The blood pressure during diastole." ;
  rdfs:subClassOf obo:VSO_0000004 .

obo:DOID_1492 a rdfs:Class ;
  rdfs:label "eye and adnexa disease" ;
  rdfs:comment "A sensory system disease that is located_in the eye or the adnexa of the eye." ;
  rdfs:subClassOf obo:DOID_0050155 .

obo:OGMS_0000015 a rdfs:Class ;
  rdfs:label "clinical history" ;
  rdfs:comment "A series of statements representing health-relevant qualities of a patient and of a patient's family."@en ;
  rdfs:subClassOf obo:OGMS_0000014 .

obo:DOID_2349 a rdfs:Class ;
  rdfs:label "arteriosclerosis" ;
  rdfs:comment "An artery disease that is characterized by a thickening and hardening of arterial walls in the arteries." ;
  rdfs:subClassOf obo:DOID_0050828 .

obo:DOID_552 a rdfs:Class ;
  rdfs:label "pneumonia" ;
  rdfs:comment "A lung disease that involves lung parenchyma or alveolar inflammation and abnormal alveolar filling with fluid (consolidation and exudation). It results from a variety of causes including infection with bacteria, viruses, fungi or parasites, and chemical or physical injury to the lungs. It is accompanied by fever, chills, cough, and difficulty in breathing." ;
  rdfs:subClassOf obo:DOID_850 .

obo:VSO_0000040 a rdfs:Class ;
  rdfs:label "systolic left ventricular pressure"@en ;
  rdfs:comment "The left ventricular pressure during systole. " ;
  rdfs:subClassOf obo:VSO_0000038 .

obo:IAO_0000594 a rdfs:Class ;
  rdfs:label "software application"@en ;
  rdfs:comment "A software application is software that can be directly executed by some processing unit."@en ;
  rdfs:subClassOf obo:IAO_0000010 .

obo:DOID_2786 a rdfs:Class ;
  rdfs:label "cerebellar disease" ;
  rdfs:subClassOf obo:DOID_936 .

obo:IAO_0000635 a rdfs:Class ;
  rdfs:label "patients section"@en ;
  rdfs:comment "A part of a document about the patients that participated in a study."@en ;
  rdfs:subClassOf obo:IAO_0000314 .

obo:OGMS_0000030 a rdfs:Class ;
  rdfs:label "predisposition to disease of type X" ;
  rdfs:comment "A disposition in an organism that constitutes an increased risk of the organism's subsequently developing the disease X."@en ;
  rdfs:subClassOf obo:BFO_0000016 .

obo:DOID_229 a rdfs:Class ;
  rdfs:label "female reproductive system disease" ;
  rdfs:comment "A reproductive system disease that impairs the ability to reproduce and is located in the uterus, vagina, cervix, ovaries or fallopian tubes." ;
  rdfs:subClassOf obo:DOID_15 .

obo:BFO_0000031 a rdfs:Class ;
  rdfs:label "generically dependent continuant"@en ;
  rdfs:comment "A continuant that is dependent on one or other independent continuant bearers. For every instance of A requires some instance of (an independent continuant type) B but which instance of B serves can change from time to time."@en ;
  rdfs:subClassOf obo:BFO_0000002 .

obo:DOID_520 a rdfs:Class ;
  rdfs:label "aortic disease" ;
  rdfs:comment "An artery disease that is characterized by degeneration of the cells composing the aortic wall." ;
  rdfs:subClassOf obo:DOID_0050828 .

obo:DOID_10865 a rdfs:Class ;
  rdfs:label "abducens nerve disease" ;
  rdfs:subClassOf obo:DOID_3817 .

obo:IAO_0000304 a rdfs:Class ;
  rdfs:label "caption"@en ;
  rdfs:comment "A textual entity that describes a figure"@en ;
  rdfs:subClassOf obo:IAO_0000300 .

<https://w3id.org/linkml/Any> a rdfs:Class ;
  rdfs:comment "An unconstrained type or object" .

obo:DOID_574 a rdfs:Class ;
  rdfs:label "peripheral nervous system disease" ;
  rdfs:comment "A nervous system disease that affects the peripheral nervous system." ;
  rdfs:subClassOf obo:DOID_863 .

obo:IAO_0000005 a rdfs:Class ;
  rdfs:label "objective specification"@en ;
  rdfs:comment "a directive information entity that describes an intended process endpoint. When part of a plan specification the concretization is realized in a planned process in which the bearer tries to effect the world so that the process endpoint is achieved."@en ;
  rdfs:subClassOf obo:IAO_0000033 .

obo:VSO_0000019 a rdfs:Class ;
  rdfs:label "diastolic right ventricular pressure"@en ;
  rdfs:comment "The right ventricular pressure during diastole." ;
  rdfs:subClassOf obo:VSO_0000015 .

obo:IAO_0000225 a rdfs:Class ;
  rdfs:label "obsolescence reason specification"@en ;
  rdfs:comment "The reason for which a term has been deprecated. The allowed values come from an enumerated list of predefined terms. See the specification of these instances for more detailed definitions of each enumerated value."@en ;
  rdfs:subClassOf obo:IAO_0000102 .

obo:DOID_10952 a rdfs:Class ;
  rdfs:label "nephritis" ;
  rdfs:comment "A kidney disease that is characterized by an inflammation of the kidneys." ;
  rdfs:subClassOf obo:DOID_557 .

obo:BFO_0000147 a rdfs:Class ;
  rdfs:label "zero-dimensional continuant fiat boundary"@en ;
  rdfs:subClassOf obo:BFO_0000140 .

obo:VSO_0000008 a rdfs:Class ;
  rdfs:label "body temperature measurement datum"@en ;
  rdfs:subClassOf obo:IAO_0000109 .

obo:GO_0085030 a rdfs:Class ;
  rdfs:label "mutualism" ;
  rdfs:subClassOf obo:GO_0044403 .

obo:PR_000036907 a rdfs:Class ;
  rdfs:label "amino acid chain component" ;
  rdfs:comment """
A fiat object part that is either a modified amino-acid residue or an unmodified amino-acid residue.
""" ;
  rdfs:subClassOf obo:BFO_0000024 .

obo:BFO_0000144 a rdfs:Class ;
  rdfs:label "process profile"@en ;
  rdfs:comment "b is a process_profile =Def. there is some process c such that b process_profile_of c (axiom label in BFO2 Reference: [093-002])"@en ;
  rdfs:subClassOf obo:BFO_0000015 .

obo:GO_0006954 a rdfs:Class ;
  rdfs:label "inflammatory response" ;
  rdfs:subClassOf obo:GO_0006952 .

obo:DOID_866 a rdfs:Class ;
  rdfs:label "vein disease" ;
  rdfs:comment "A vascular disease that is located_in a vein." ;
  rdfs:subClassOf obo:DOID_178 .

obo:GO_0051702 a rdfs:Class ;
  rdfs:label "interaction with symbiont" ;
  rdfs:subClassOf obo:GO_0044419 .

obo:PATO_0002062 a rdfs:Class ;
  rdfs:label "physical quality of a process" ;
  rdfs:subClassOf obo:PATO_0001236 .

obo:IAO_0000579 a rdfs:Class ;
  rdfs:label "centrally registered identifier registry"@en ;
  rdfs:comment "A CRID registry is a dataset of CRID records, each consisting of a CRID symbol and additional information which was recorded in the dataset through a assigning a centrally registered identifier process."@en ;
  rdfs:subClassOf obo:IAO_0000100 .

obo:IAO_0000315 a rdfs:Class ;
  rdfs:label "abstract"@en ;
  rdfs:comment "A summary of the entire document that is substantially smaller than the document it summarizes.  It is about the document it summarizes."@en ;
  rdfs:subClassOf obo:IAO_0000314 .

obo:PATO_0000402 a rdfs:Class ;
  rdfs:label "branched" ;
  rdfs:subClassOf obo:PATO_0002009 .

obo:IAO_0000639 a rdfs:Class ;
  rdfs:label "related work section"@en ;
  rdfs:comment "A part of a document about work in other publications that is relevant to the content of the document."@en ;
  rdfs:subClassOf obo:IAO_0000314 .

obo:DOID_224 a rdfs:Class ;
  rdfs:label "transient cerebral ischemia" ;
  rdfs:subClassOf obo:DOID_2316 .

obo:DOID_2451 a rdfs:Class ;
  rdfs:label "protein S deficiency" ;
  rdfs:subClassOf obo:DOID_2452 , obo:DOID_620 .

<https://raw.githubusercontent.com/aellenhicks/htn_owl/master/htn.owl/_:genid12164> a rdfs:Class .

obo:BFO_0000160 a rdf:Property ;
  rdfs:domain <https://raw.githubusercontent.com/aellenhicks/htn_owl/master/htn.owl/_:genid12164> ;
  rdfs:range xsd:string .

obo:DOID_3093 a rdfs:Class ;
  rdfs:label "nervous system cancer" ;
  rdfs:comment "An organ system cancer located_in the nervous system that affects the central or peripheral nervous system." ;
  rdfs:subClassOf obo:DOID_0050686 .

obo:DOID_8483 a rdfs:Class ;
  rdfs:label "retinal artery occlusion" ;
  rdfs:subClassOf obo:DOID_1729 .

obo:DOID_14159 a rdfs:Class ;
  rdfs:label "obstructive hydrocephalus" ;
  rdfs:subClassOf obo:DOID_10908 .

<http://www.geneontology.org/formats/oboInOwl#SynonymType> a rdfs:Class ;
  rdfs:subClassOf obo:IAO_0000102 .

obo:HTN_00000045 a rdfs:Class ;
  rdfs:label "stage 1 elevated adult diastolic blood pressure measurement datum per 2017 guidelines"@en ;
  rdfs:subClassOf obo:HTN_00000044 .

obo:IAO_0000179 a rdfs:Class ;
  rdfs:label "histogram"@en ;
  rdfs:comment """A histogram is a report graph which is a statistical description of a
distribution in terms of occurrence frequencies of different event classes."""@en ;
  rdfs:subClassOf obo:IAO_0000038 .

obo:DOID_0060319 a rdfs:Class ;
  rdfs:label "cardiac arrest" ;
  rdfs:comment "A congestive heart failure characterized by a sudden stop in effective blood circulation due to the failure of the heart to contract effectively or at all." ;
  rdfs:subClassOf obo:DOID_6000 .

obo:OGMS_0000061 a rdfs:Class ;
  rdfs:label "pathological bodily process" ;
  rdfs:comment "A bodily process that is clinically abnormal."@en ;
  rdfs:subClassOf obo:OGMS_0000060 .

obo:HTN_00000001 a rdfs:Class ;
  rdfs:label "systolic blood pressure measurement datum"@en ;
  rdfs:comment "A blood pressure measurement datum that is a quality measure of some systolic blood pressure" ;
  rdfs:subClassOf obo:VSO_0000005 .

obo:DOID_0060158 a rdfs:Class ;
  rdfs:label "acquired metabolic disease" ;
  rdfs:comment "A disease of metabolism that has _material_basis_in enzyme deficiency or accumulation of enzymes or toxins which interfere with normal function due to an endocrine organ disease, organ malfunction, inadequate intake, dietary deficiency, or malabsorption." ;
  rdfs:subClassOf obo:DOID_0014667 .

obo:PATO_0001025 a rdfs:Class ;
  rdfs:label "pressure"@en ;
  rdfs:comment "A physical quality that inheres in a bearer by virtue of the bearer's amount of force per unit area it exerts." ;
  rdfs:subClassOf obo:BFO_0000019 .

obo:OGMS_0000090 a rdfs:Class ;
  rdfs:label "treatment" ;
  rdfs:comment "A planned process whose completion is hypothesized by a health care provider to eliminate a disorder or to alleviate the signs and symptoms of a disorder."@en ;
  rdfs:subClassOf obo:OBI_0000011 .

obo:IAO_0000310 a rdfs:Class ;
  rdfs:label "document"@en ;
  rdfs:comment "A collection of information content entities intended to be understood together as a whole"@en ;
  rdfs:subClassOf obo:IAO_0000030 .

obo:DOID_178 a rdfs:Class ;
  rdfs:label "vascular disease" ;
  rdfs:comment "A cardiovascular system disease that primarily affects the blood vessels which includes the arteries, veins and capillaries that carry blood to and from the heart." ;
  rdfs:subClassOf obo:DOID_1287 .

obo:HTN_00000049 a rdfs:Class ;
  rdfs:label "stage 1 adult blood pressure measurement datum per 2017 guidelines"@en ;
  rdfs:comment "130–139 mm Hg or 80–89 mm Hg" ;
  rdfs:subClassOf obo:HTN_00000015 .

obo:GO_0007585 a rdfs:Class ;
  rdfs:label "respiratory gaseous exchange" ;
  rdfs:subClassOf obo:GO_0032501 .

obo:IAO_0000328 a rdfs:Class ;
  rdfs:label "table of figures"@en ;
  rdfs:comment "A table that relates figures in a document to specific locations in that document (usually page numbers).  This is also a document part (subsumption there should be inferred)."@en ;
  rdfs:subClassOf obo:IAO_0000306 .

obo:IAO_0000616 a rdfs:Class ;
  rdfs:label "conflict of interest section"@en ;
  rdfs:comment "A part of a document used to declare any competing interests regarding the authors and/or funding organization for the work described in the document."@en ;
  rdfs:subClassOf obo:IAO_0000314 .

obo:DOID_61 a rdfs:Class ;
  rdfs:label "mitral valve disease" ;
  rdfs:subClassOf obo:DOID_4079 .

<https://raw.githubusercontent.com/aellenhicks/htn_owl/master/htn.owl/_:genid12160> a rdfs:Class .

obo:BFO_0000159 a rdf:Property ;
  rdfs:domain <https://raw.githubusercontent.com/aellenhicks/htn_owl/master/htn.owl/_:genid12160> ;
  rdfs:range xsd:string .

obo:IAO_0000400 a rdfs:Class ;
  rdfs:label "cartesian spatial coordinate datum"@en ;
  rdfs:comment "A cartesian spatial coordinate datum is a representation of a point in a spatial region, in which equal changes in the magnitude of a coordinate value denote length qualities with the same magnitude"@en ;
  rdfs:subClassOf obo:IAO_0000027 .

obo:OGMS_0000102 a rdfs:Class ;
  rdfs:label "injury" ;
  rdfs:comment "A disorder that involves some structural damage that is immediately caused by a catastrophic external force."@en ;
  rdfs:subClassOf obo:OGMS_0000045 .

obo:IAO_0000609 a rdfs:Class ;
  rdfs:label "author summary section"@en ;
  rdfs:comment "A part of a document, distinct from the abstract, that describes the significance and broader context of the document content. The author summary is often written in a non-technical manner and is aimed at both scientists and non-scientist readers."@en ;
  rdfs:subClassOf obo:IAO_0000314 .

obo:IAO_0000027 a rdfs:Class ;
  rdfs:label "data item"@en ;
  rdfs:comment "a data item is an information content entity that is intended to be a truthful statement about something (modulo, e.g., measurement precision or other systematic errors) and is constructed/acquired by a method which reliably tends to produce (approximately) truthful statements."@en ;
  rdfs:subClassOf obo:IAO_0000030 .

obo:DOID_12375 a rdfs:Class ;
  rdfs:label "bronchopneumonia" ;
  rdfs:comment "A pneumonia involving inflammation of lungs that begins in the terminal bronchioles, which become clogged with thick mucus that forms consolidated patches in adjacent lobules. It is caused by bacteria and viruses." ;
  rdfs:subClassOf obo:DOID_552 .

obo:BFO_0000024 a rdfs:Class ;
  rdfs:label "fiat object part" ;
  rdfs:subClassOf obo:BFO_0000040 .

obo:NCBITaxon_2 a rdfs:Class ;
  rdfs:label "Bacteria" ;
  rdfs:subClassOf obo:NCBITaxon_131567 .

obo:IAO_0000078 a rdfs:Class ;
  rdfs:label "curation status specification"@en ;
  rdfs:comment "The curation status of the term. The allowed values come from an enumerated list of predefined terms. See the specification of these instances for more detailed definitions of each enumerated value."@en ;
  rdfs:subClassOf obo:IAO_0000102 .

obo:DOID_0060086 a rdfs:Class ;
  rdfs:label "female reproductive organ benign neoplasm" ;
  rdfs:subClassOf obo:DOID_0050622 .

obo:GAZ_00000448 a rdfs:Class ;
  rdfs:label "geographic location" ;
  rdfs:comment "A reference to a place on the Earth, by its name or by its geographical location." ;
  rdfs:subClassOf obo:BFO_0000029 .

obo:OGMS_0000050 a rdfs:Class ;
  rdfs:label "acquired genetic disorder" ;
  rdfs:comment "A genetic disorder acquired by a single cell in an organism that leads to a population of cells within the organism bearing the disorder."@en ;
  rdfs:subClassOf obo:OGMS_0000047 .

obo:DOID_0060043 a rdfs:Class ;
  rdfs:label "sexual disorder" ;
  rdfs:comment "A disease of mental health that involves the impairment in normal sexual functioning." ;
  rdfs:subClassOf obo:DOID_150 .

obo:BFO_0000052 a rdf:Property ;
  rdfs:label "inheres in at all times"@en ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0000052 .

obo:BFO_0000067 a rdf:Property ;
  rdfs:label "contains process"@en ;
  rdfs:comment "[copied from inverse property 'occurs in'] b occurs_in c =def b is a process and c is a material entity or immaterial entity& there exists a spatiotemporal region r and b occupies_spatiotemporal_region r.& forall(t) if b exists_at t then c exists_at t & there exist spatial regions s and s’ where & b spatially_projects_onto s at t& c is occupies_spatial_region s’ at t& s is a proper_continuant_part_of s’ at t"@en ;
  rdfs:range <https://w3id.org/linkml/Any> .

obo:BFO_0000179 a rdf:Property ;
  rdfs:label "BFO OWL specification label"@en ;
  rdfs:comment "Relates an entity in the ontology to the name of the variable that is used to represent it in the code that generates the BFO OWL file from the lispy specification."@en ;
  rdfs:range xsd:string .

obo:BFO_0000180 a rdf:Property ;
  rdfs:label "BFO CLIF specification label"@en ;
  rdfs:comment "Relates an entity in the ontology to the term that is used to represent it in the the CLIF specification of BFO2"@en ;
  rdfs:range xsd:string .

obo:IAO_0000111 a rdf:Property ;
  rdfs:label "editor preferred label" ;
  rdfs:comment "The concise, meaningful, and human-friendly name for a class or property preferred by the ontology developers. (US-English)"@en ;
  rdfs:range xsd:string .

obo:IAO_0000112 a rdf:Property ;
  rdfs:label "example of usage"@en ;
  rdfs:comment "A phrase describing how a class name should be used. May also include other kinds of examples that facilitate immediate understanding of a class semantics, such as widely known prototypical subclasses or instances of the class. Although essential for high level terms, examples for low level terms (e.g., Affymetrix HU133 array) are not"@en ;
  rdfs:range xsd:string .

obo:IAO_0000113 a rdf:Property ;
  rdfs:label "in branch"@en ;
  rdfs:comment "An annotation property indicating which module the terms belong to. This is currently experimental and not implemented yet."@en ;
  rdfs:range xsd:string .

obo:IAO_0000114 a rdf:Property ;
  rdfs:label "has curation status"@en ;
  rdfs:range xsd:string .

obo:IAO_0000115 a rdf:Property ;
  rdfs:label "textual definition" ;
  rdfs:comment "The official OBI definition, explaining the meaning of a class or property. Shall be Aristotelian, formalized and normalized. Can be augmented with colloquial definitions."@en ;
  rdfs:range xsd:string .

obo:IAO_0000116 a rdf:Property ;
  rdfs:label "editor note" ;
  rdfs:comment "An administrative note intended for its editor. It may not be included in the publication version of the ontology, so it should contain nothing necessary for end users to understand the ontology."@en ;
  rdfs:range xsd:string .

obo:IAO_0000117 a rdf:Property ;
  rdfs:label "definition editor" ;
  rdfs:comment "Name of editor entering the term in the file. The term editor is a point of contact for information regarding the term. The term editor may be, but is not always, the author of the definition, which may have been worked upon by several people"@en ;
  rdfs:range xsd:string .

obo:IAO_0000118 a rdf:Property ;
  rdfs:label "alternative term"@en ;
  rdfs:comment "An alternative name for a class or property which means the same thing as the preferred name (semantically equivalent)"@en ;
  rdfs:range xsd:string .

obo:IAO_0000119 a rdf:Property ;
  rdfs:label "definition source" ;
  rdfs:comment "formal citation, e.g. identifier in external database to indicate / attribute source(s) for the definition. Free text indicate / attribute source(s) for the definition. EXAMPLE: Author Name, URI, MeSH Term C04, PUBMED ID, Wiki uri on 31.01.2007"@en ;
  rdfs:range xsd:string .

obo:IAO_0000142 a rdf:Property ;
  rdfs:label "mentions"@en ;
  rdfs:comment "An information artifact IA mentions an entity E exactly when it has a component/part that denotes E"@en ;
  rdfs:range obo:BFO_0000001 ;
  rdfs:subPropertyOf obo:IAO_0000136 .

obo:IAO_0000231 a rdf:Property ;
  rdfs:label "has obsolescence reason"@en ;
  rdfs:comment "Relates an annotation property to an obsolescence reason. The values of obsolescence reasons come from a list of predefined terms, instances of the class obsolescence reason specification."@en ;
  rdfs:range xsd:string .

obo:IAO_0000232 a rdf:Property ;
  rdfs:label "curator note" ;
  rdfs:comment "An administrative note of use for a curator but of no use for a user"@en ;
  rdfs:range xsd:string .

obo:IAO_0000233 a rdf:Property ;
  rdfs:label "term tracker item"@en ;
  rdfs:comment "An IRI or similar locator for a request or discussion of an ontology term." ;
  rdfs:range xsd:string .

obo:IAO_0000234 a rdf:Property ;
  rdfs:label "ontology term requester"@en ;
  rdfs:comment "The name of the person, project, or organization that motivated inclusion of an ontology term by requesting its addition." ;
  rdfs:range xsd:string .

obo:IAO_0000411 a rdf:Property ;
  rdfs:label "is denotator type" ;
  rdfs:comment "relates an class defined in an ontology, to the type of it's denotator" ;
  rdfs:range xsd:string .

obo:IAO_0000412 a rdf:Property ;
  rdfs:label "imported from"@en ;
  rdfs:comment "For external terms/classes, the ontology from which the term was imported"@en ;
  rdfs:range xsd:string .

obo:IAO_0000419 a rdf:Property ;
  rdfs:label "quality is specified as"@en ;
  rdfs:comment "inverse of the relation of is quality specification of"@en ;
  rdfs:range obo:IAO_0000027 .

obo:IAO_0000424 a rdf:Property ;
  rdfs:label "expand expression to" ;
  rdfs:comment "A macro expansion tag applied to an object property (or possibly a data property)  which can be used by a macro-expansion engine to generate more complex expressions from simpler ones"@en ;
  rdfs:range xsd:string .

obo:IAO_0000425 a rdf:Property ;
  rdfs:label "expand assertion to"@en ;
  rdfs:comment "A macro expansion tag applied to an annotation property which can be expanded into a more detailed axiom."@en ;
  rdfs:range xsd:string .

obo:IAO_0000426 a rdf:Property ;
  rdfs:label "first order logic expression"@en ;
  rdfs:comment "An assertion that holds between an OWL Object Property and a string or literal, where the value of the string or literal is a Common Logic sentence of collection of sentences that define the Object Property." ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002422 .

obo:IAO_0000427 a rdf:Property ;
  rdfs:label "antisymmetric property"@en ;
  rdfs:comment "use boolean value xsd:true to indicate that the property is an antisymmetric property"@en ;
  rdfs:range xsd:string .

obo:IAO_0000589 a rdf:Property ;
  rdfs:label "obo foundry unique label" ;
  rdfs:comment "An alternative name for a class or property which is unique across the OBO Foundry."@en ;
  rdfs:range xsd:string .

obo:IAO_0000596 a rdf:Property ;
  rdfs:label "has ID digit count"@en ;
  rdfs:comment "Relates an ontology used to record id policy to the number of digits in the URI. The URI is: the 'has ID prefix\" annotation property value concatenated with an integer in the id range (left padded with \"0\"s to make this many digits)" ;
  rdfs:range xsd:string .

obo:IAO_0000597 a rdf:Property ;
  rdfs:label "has ID range allocated to"@en ;
  rdfs:comment "Relates a datatype that encodes a range of integers to the name of the person or organization who can use those ids constructed in that range to define new terms" ;
  rdfs:range xsd:string .

obo:IAO_0000598 a rdf:Property ;
  rdfs:label "has ID policy for" ;
  rdfs:comment "Relating an ontology used to record id policy to the ontology namespace whose policy it manages" ;
  rdfs:range xsd:string .

obo:IAO_0000599 a rdf:Property ;
  rdfs:label "has ID prefix"@en ;
  rdfs:comment "Relates an ontology used to record id policy to a prefix concatenated with an integer in the id range (left padded with \"0\"s to make this many digits) to construct an ID for a term being created." ;
  rdfs:range xsd:string .

obo:IAO_0000600 a rdf:Property ;
  rdfs:label "elucidation"@en ;
  rdfs:range xsd:string .

obo:IAO_0000601 a rdf:Property ;
  rdfs:label "has associated axiom(nl)"@en ;
  rdfs:range xsd:string .

obo:IAO_0000602 a rdf:Property ;
  rdfs:label "has associated axiom(fol)"@en ;
  rdfs:range xsd:string .

obo:IAO_0000603 a rdf:Property ;
  rdfs:label "is allocated id range"@en ;
  rdfs:comment "Relates an ontology IRI to an (inclusive) range of IRIs in an OBO name space. The range is give as, e.g. \"IAO_0020000-IAO_0020999\""@en ;
  rdfs:range xsd:string .

obo:IAO_0000604 a rdf:Property ;
  rdfs:label "retired from use as of" ;
  rdfs:comment "relates a class of CRID to the date after which further instances should not be made, according to the central authority" ;
  rdfs:range xsd:string .

obo:IAO_0010000 a rdf:Property ;
  rdfs:label "has axiom label"@en ;
  rdfs:range xsd:string .

obo:IAO_0100001 a rdf:Property ;
  rdfs:label "term replaced by"@en ;
  rdfs:comment "Use on obsolete terms, relating the term to another term that can be used as a substitute"@en ;
  rdfs:range xsd:string .

obo:RO_0000080 a rdf:Property ;
  rdfs:label "quality of"@en ;
  rdfs:comment "a relation between a quality and an independent continuant (the bearer), in which the quality specifically depends on the bearer for its existence"@en ;
  rdfs:range obo:BFO_0000004 ;
  rdfs:subPropertyOf obo:RO_0000052 .

obo:RO_0001019 a rdf:Property ;
  rdfs:label "contains"@en ;
  rdfs:range <https://w3id.org/linkml/Any> .

obo:RO_0001022 a rdf:Property ;
  rdfs:label "has allergic trigger"@en ;
  rdfs:comment "A relation between a condition (a phenotype or disease) of a host and a material entity, in which the material entity is not part of the host, and is considered harmless to non-allergic hosts, and the condition results in pathological processes that include an abnormally strong immune response against the material entity." ;
  rdfs:range obo:BFO_0000040 ;
  rdfs:subPropertyOf obo:RO_0003302 .

obo:RO_0001023 a rdf:Property ;
  rdfs:label "has autoimmune trigger"@en ;
  rdfs:comment "A relation between a condition (a phenotype or disease) of a host and a material entity, in which the material entity is part of the host itself, and the condition results in pathological processes that include an abnormally strong immune response against the material entity." ;
  rdfs:range obo:BFO_0000040 ;
  rdfs:subPropertyOf obo:RO_0003302 .

obo:RO_0001900 a rdf:Property ;
  rdfs:label "temporal interpretation"@en ;
  rdfs:comment "An assertion that holds between an OWL Object Property and a temporal interpretation that elucidates how OWL Class Axioms that use this property are to be interpreted in a temporal context." ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002422 .

obo:RO_0002004 a rdf:Property ;
  rdfs:label "tracheates"@en ;
  rdfs:comment "The relationship that holds between a trachea or tracheole and an antomical structure that is contained in (and so provides an oxygen supply to)." ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0001018 .

obo:RO_0002006 a rdf:Property ;
  rdfs:label "has synaptic terminal of"@en ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002131 .

obo:RO_0002007 a rdf:Property ;
  rdfs:label "bounding layer of"@en ;
  rdfs:comment """X outer_layer_of Y iff:
. X :continuant that bearer_of some PATO:laminar
. X part_of Y
. exists Z :surface
. X has_boundary Z
. Z boundary_of Y

has_boundary: http://purl.obolibrary.org/obo/RO_0002002
boundary_of: http://purl.obolibrary.org/obo/RO_0002000""" ;
  rdfs:range obo:BFO_0000040 ;
  rdfs:subPropertyOf obo:BFO_0000050 .

obo:RO_0002008 a rdf:Property ;
  rdfs:label "coincident with" ;
  rdfs:comment "A relation that holds between two linear structures that are approximately parallel to each other for their entire length and where either the two structures are adjacent to each other or one is part of the other." ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002323 .

obo:RO_0002081 a rdf:Property ;
  rdfs:label "before or simultaneous with"@en ;
  rdfs:comment "Primitive instance level timing relation between events" ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002222 .

obo:RO_0002082 a rdf:Property ;
  rdfs:label "simultaneous with"@en ;
  rdfs:comment "t1 simultaneous_with t2 iff:=  t1 before_or_simultaneous_with t2  and not (t1 before t2)"@en ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002081 .

obo:RO_0002083 a rdf:Property ;
  rdfs:label "before"@en ;
  rdfs:comment "t1 before t2 iff:=  t1 before_or_simulataneous_with t2  and not (t1 simultaeous_with t2)"@en ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002081 .

obo:RO_0002084 a rdf:Property ;
  rdfs:label "during which ends"@en ;
  rdfs:comment "Previously had ID  http://purl.obolibrary.org/obo/RO_0002122 in test files in sandpit - but this seems to have been dropped from ro-edit.owl at some point.  No re-use under this ID AFAIK, but leaving note here in case we run in to clashes down the line.  Official ID now chosen from DOS ID range." ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002222 .

obo:RO_0002085 a rdf:Property ;
  rdfs:label "encompasses"@en ;
  rdfs:comment "Previously had ID  http://purl.obolibrary.org/obo/RO_0002124 in test files in sandpit - but this seems to have been dropped from ro-edit.owl at some point.  No re-use under this ID AFAIK, but leaving note here in case we run in to clashes down the line.  Official ID now chosen from DOS ID range." ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002088 .

obo:RO_0002086 a rdf:Property ;
  rdfs:label "ends after"@en ;
  rdfs:comment "X ends_after Y iff: end(Y) before_or_simultaneous_with end(X)"@en ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002222 .

obo:RO_0002087 a rdf:Property ;
  rdfs:label "immediately preceded by"@en ;
  rdfs:comment "X immediately_preceded_by Y iff: end(X) simultaneous_with start(Y)"@en ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:BFO_0000062 .

obo:RO_0002088 a rdf:Property ;
  rdfs:label "during which starts"@en ;
  rdfs:comment "Previously had ID  http://purl.obolibrary.org/obo/RO_0002123 in test files in sandpit - but this seems to have been dropped from ro-edit.owl at some point.  No re-use under this ID AFAIK, but leaving note here in case we run in to clashes down the line.  Official ID now chosen from DOS ID range." ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002222 .

obo:RO_0002089 a rdf:Property ;
  rdfs:label "starts before"@en ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002222 .

obo:RO_0002090 a rdf:Property ;
  rdfs:label "immediately precedes"@en ;
  rdfs:comment "X immediately_precedes_Y iff: end(X) simultaneous_with start(Y)"@en ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:BFO_0000063 .

obo:RO_0002092 a rdf:Property ;
  rdfs:label "happens during"@en ;
  rdfs:comment "X happens_during Y iff: (start(Y) before_or_simultaneous_with start(X)) AND (end(X) before_or_simultaneous_with end(Y))"@en ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002093 .

obo:RO_0002093 a rdf:Property ;
  rdfs:label "ends during"@en ;
  rdfs:comment "X ends_during Y iff: ((start(Y) before_or_simultaneous_with end(X)) AND end(X) before_or_simultaneous_with end(Y). "@en ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002222 .

obo:RO_0002100 a rdf:Property ;
  rdfs:label "has soma location"@en ;
  rdfs:comment "Relation between a neuron and an anatomical structure that its soma is part of."@en ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002131 .

obo:RO_0002101 a rdf:Property ;
  rdfs:label "fasciculates with"@en ;
  rdfs:comment """relationship between a neuron and a neuron projection bundle (e.g.- tract or nerve bundle) that one or more of its projections travels through.
"""@en ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002131 .

obo:RO_0002102 a rdf:Property ;
  rdfs:label "axon synapses in"@en ;
  rdfs:comment "Relation between a neuron and some structure its axon forms (chemical) synapses in."@en ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002113 .

obo:RO_0002104 a rdf:Property ;
  rdfs:label "has plasma membrane part"@en ;
  rdfs:comment """
Holds between a cell c and a protein complex or protein p if and only if that cell has as part a plasma_membrane[GO:0005886], and that plasma membrane has p as part.
""" ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:BFO_0000051 .

obo:RO_0002110 a rdf:Property ;
  rdfs:label "has postsynaptic terminal in"@en ;
  rdfs:comment "Relation between a neuron and some structure (e.g.- a brain region) in which it receives (chemical) synaptic input. "@en ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002130 .

obo:RO_0002113 a rdf:Property ;
  rdfs:label "has presynaptic terminal in"@en ;
  rdfs:comment "Relation between a neuron and some structure (e.g.- a brain region) in which it receives (chemical) synaptic input."@en ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002130 .

obo:RO_0002121 a rdf:Property ;
  rdfs:label "dendrite synapsed in"@en ;
  rdfs:comment """Relation between a neuron and some structure  (e.g.- a brain region) in which its dendrite receives synaptic input.

\t"""@en ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002110 .

obo:RO_0002130 a rdf:Property ;
  rdfs:label "has synaptic terminal in"@en ;
  rdfs:comment "A general relation between a neuron and some structure in which it either chemically synapses to some target or in which it receives (chemical) synaptic input." ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002131 .

obo:RO_0002131 a rdf:Property ;
  rdfs:label "overlaps"@en ;
  rdfs:comment """
x overlaps y if and only if there exists some z such that x has part z and z part of y
""" ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002323 .

obo:RO_0002132 a rdf:Property ;
  rdfs:label "has fasciculating neuron projection"@en ;
  rdfs:comment "The relation between a neuron projection bundle and a neuron projection that is fasciculated with it."@en ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002131 .

obo:RO_0002151 a rdf:Property ;
  rdfs:label "partially overlaps"@en ;
  rdfs:comment "x partially overlaps y iff there exists some z such that z is part of x and z is part of y, and it is also the case that neither x is part of y or y is part of x" ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002131 .

obo:RO_0002161 a rdf:Property ;
  rdfs:label "never in taxon" ;
  rdfs:comment "x never in taxon T if and only if T is a class, and x does not instantiate the class expression \"in taxon some T\". Note that this is a shortcut relation, and should be used as a hasValue restriction in OWL." ;
  rdfs:seeAlso <https://github.com/obophenotype/uberon/wiki/Taxon-constraints> ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002172 .

obo:RO_0002163 a rdf:Property ;
  rdfs:label "spatially disjoint from" ;
  rdfs:comment "A is spatially_disjoint_from B if and only if they have no parts in common" ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002323 .

obo:RO_0002170 a rdf:Property ;
  rdfs:label "connected to"@en ;
  rdfs:comment "a is connected to b if and only if a and b are discrete structure, and there exists some connecting structure c, such that c connects a and b" ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002323 .

obo:RO_0002171 a rdf:Property ;
  rdfs:label "mutually spatially disjoint with"@en ;
  rdfs:comment "A is mutually_spatially_disjoint_with B if both A and B are classes, and there exists no p such that p is part_of some A and p is part_of some B." ;
  rdfs:seeAlso obo:RO_0002163 ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002420 .

obo:RO_0002172 a rdf:Property ;
  rdfs:label "taxonomic class assertion"@en ;
  rdfs:comment "An assertion that holds between an ontology class and an organism taxon class, which is intepreted to yield some relationship between instances of the ontology class and the taxon." ;
  rdfs:seeAlso <https://github.com/obophenotype/uberon/wiki/Taxon-constraints> ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002420 .

obo:RO_0002173 a rdf:Property ;
  rdfs:label "ambiguous for taxon"@en ;
  rdfs:comment "S ambiguous_for_taxon T if the class S does not have a clear referent in taxon T. An example would be the class 'manual digit 1', which encompasses a homology hypotheses that is accepted for some species (e.g. human and mouse), but does not have a clear referent in Aves - the referent is dependent on the hypothesis embraced, and also on the ontogenetic stage.  [PHENOSCPAE:asilomar_mtg]" ;
  rdfs:seeAlso <https://github.com/obophenotype/uberon/wiki/Taxon-constraints> ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002172 .

obo:RO_0002174 a rdf:Property ;
  rdfs:label "dubious for taxon"@en ;
  rdfs:comment "S dubious_for_taxon T if it is probably the case that no instances of S can be found in any instance of T." ;
  rdfs:seeAlso <https://github.com/obophenotype/uberon/wiki/Taxon-constraints> ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002172 .

obo:RO_0002175 a rdf:Property ;
  rdfs:label "present in taxon"@en ;
  rdfs:comment "S present_in_taxon T if some instance of T has some S. This does not means that all instances of T have an S - it may only be certain life stages or sexes that have S" ;
  rdfs:seeAlso <https://github.com/obophenotype/uberon/wiki/Taxon-constraints> ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002172 .

obo:RO_0002178 a rdf:Property ;
  rdfs:label "supplies"@en ;
  rdfs:comment "Relation between an arterial structure and another structure, where the arterial structure acts as a conduit channeling fluid, substance or energy." ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002170 .

obo:RO_0002179 a rdf:Property ;
  rdfs:label "drains"@en ;
  rdfs:comment "Relation between an collecting structure and another structure, where the collecting structure acts as a conduit channeling fluid, substance or energy away from the other structure." ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002170 .

obo:RO_0002180 a rdf:Property ;
  rdfs:label "has component"@en ;
  rdfs:comment "w 'has component' p if w 'has part' p and w is such that it can be directly disassembled into into n parts p, p2, p3, ..., pn, where these parts are of similar type." ;
  rdfs:seeAlso <http://ontologydesignpatterns.org/wiki/Submissions:Componency> ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:BFO_0000051 .

obo:RO_0002212 a rdf:Property ;
  rdfs:label "negatively regulates"@en ;
  rdfs:comment "x negatively regulates y if and only if the progression of x reduces the frequency, rate or extent of y" ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002305 , obo:RO_0002211 .

obo:RO_0002213 a rdf:Property ;
  rdfs:label "positively regulates"@en ;
  rdfs:comment "x positively regulates y if and only if the progression of x increases the frequency, rate or extent of y" ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002304 , obo:RO_0002211 .

obo:RO_0002217 a rdf:Property ;
  rdfs:label "actively participates in"@en ;
  rdfs:comment "x actively participates in y if and only if x participates in y and x realizes some active role" ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0000056 .

obo:RO_0002218 a rdf:Property ;
  rdfs:label "has active participant"@en ;
  rdfs:comment "x has participant y if and only if x realizes some active role that inheres in y" ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0000057 .

obo:RO_0002219 a rdf:Property ;
  rdfs:label "surrounded by"@en ;
  rdfs:comment "x surrounded_by y if and only if (1) x is adjacent to y and for every region r that is adjacent to x, r overlaps y (2) the shared boundary between x and y occupies the majority of the outermost boundary of x" ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002220 .

obo:RO_0002221 a rdf:Property ;
  rdfs:label "surrounds"@en ;
  rdfs:comment "inverse of surrounded by" ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002220 .

obo:RO_0002223 a rdf:Property ;
  rdfs:label "starts"@en ;
  rdfs:comment "inverse of starts with" ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002222 , obo:BFO_0000050 .

obo:RO_0002224 a rdf:Property ;
  rdfs:label "starts with"@en ;
  rdfs:comment "x starts with y if and only if x has part y and the time point at which x starts is equivalent to the time point at which y starts. Formally: α(y) = α(x) ∧ ω(y) < ω(x), where α is a function that maps a process to a start point, and ω is a function that maps a process to an end point." ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002222 , obo:BFO_0000051 .

obo:RO_0002229 a rdf:Property ;
  rdfs:label "ends"@en ;
  rdfs:comment "inverse of ends with" ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002222 , obo:BFO_0000050 .

obo:RO_0002230 a rdf:Property ;
  rdfs:label "ends with"@en ;
  rdfs:comment "x ends with y if and only if x has part y and the time point at which x ends is equivalent to the time point at which y ends. Formally: α(y) > α(x) ∧ ω(y) = ω(x), where α is a function that maps a process to a start point, and ω is a function that maps a process to an end point." ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002222 , obo:BFO_0000051 .

obo:RO_0002233 a rdf:Property ;
  rdfs:label "has input"@en ;
  rdfs:comment "p has direct input c iff c is a participant in p, c is present at the start of p, and the state of c is modified during p." ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0000057 .

obo:RO_0002234 a rdf:Property ;
  rdfs:label "has output"@en ;
  rdfs:comment "p has output c iff c is a participant in p, c is present at the end of p, and c is not present at the beginning of p." ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0000057 .

obo:RO_0002240 a rdf:Property ;
  rdfs:label "has exposure receptor" ;
  rdfs:comment "A broad relationship between an exposure event or process and any entity (e.g., a human, human population, or a human organ) that interacts with an exposure stressor during the exposure event" ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002244 .

obo:RO_0002241 a rdf:Property ;
  rdfs:label "has exposure stressor" ;
  rdfs:comment "A broad relationship between an exposure event or process and any agent, stimulus, activity, or event that causes stress or tension on an organism and interacts with an exposure receptor during an exposure event." ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002244 .

obo:RO_0002242 a rdf:Property ;
  rdfs:label "has exposure route" ;
  rdfs:comment "A broad relationship between an exposure event or process and a process by which the exposure stressor comes into contact with the exposure receptor" ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002244 .

obo:RO_0002243 a rdf:Property ;
  rdfs:label "has exposure transport path" ;
  rdfs:comment "A broad relationship between an exposure event or process and a the material an agent takes from the source to the target." ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002244 .

obo:RO_0002248 a rdf:Property ;
  rdfs:label "has active ingredient" ;
  rdfs:comment "A relationship that holds between a substance and a chemical entity, if the chemical entity is part of the substance, and the chemical entity forms the biologically active component of the substance." ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:BFO_0000051 .

obo:RO_0002249 a rdf:Property ;
  rdfs:label "active ingredient in'" ;
  rdfs:comment "inverse of has active ingredient" ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:BFO_0000050 .

obo:RO_0002252 a rdf:Property ;
  rdfs:label "connecting branch of" ;
  rdfs:comment "b connecting-branch-of s iff b is connected to s, and there exists some tree-like structure t such that the mereological sum of b plus s is either the same as t or a branching-part-of t." ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002375 .

obo:RO_0002253 a rdf:Property ;
  rdfs:label "has connecting branch" ;
  rdfs:comment "inverse of connecting branch of" ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002375 .

obo:RO_0002259 a rdf:Property ;
  rdfs:label "defined by inverse" ;
  rdfs:range xsd:string .

obo:RO_0002260 a rdf:Property ;
  rdfs:label "has biological role" ;
  rdfs:comment "c has-biological-role r iff c has-role r and r is a biological role (CHEBI:24432)" ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0000087 .

obo:RO_0002261 a rdf:Property ;
  rdfs:label "has application role" ;
  rdfs:comment "c has-application-role r iff c has-role r and r is an application role (CHEBI:33232)" ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0000087 .

obo:RO_0002262 a rdf:Property ;
  rdfs:label "has chemical role" ;
  rdfs:comment "c has-chemical-role r iff c has-role r and r is a chemical role (CHEBI:51086)" ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0000087 .

obo:RO_0002263 a rdf:Property ;
  rdfs:label "acts upstream of" ;
  rdfs:comment "c involved in regulation of p if c enables  'p' and p' causally upstream of p" ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002264 .

obo:RO_0002264 a rdf:Property ;
  rdfs:label "acts upstream of or within" ;
  rdfs:comment "c acts upstream of or within p if c is enables 'p' and p' causally upstream of or within p" ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002500 .

obo:RO_0002302 a rdf:Property ;
  rdfs:label "is treated by substance" ;
  rdfs:comment "Inverse of 'is substance that treats'" ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002410 .

obo:RO_0002304 a rdf:Property ;
  rdfs:label "causally upstream of, positive effect" ;
  rdfs:comment "holds between x and y if and only if x is causally upstream of y and the progression of x increases the frequency, rate or extent of y" ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002411 .

obo:RO_0002305 a rdf:Property ;
  rdfs:label "causally upstream of, negative effect" ;
  rdfs:comment "holds between x and y if and only if x is causally upstream of y and the progression of x decreases the frequency, rate or extent of y" ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002411 .

obo:RO_0002323 a rdf:Property ;
  rdfs:label "mereotopologically related to"@en ;
  rdfs:comment """
A mereological relationship or a topological relationship
""" ;
  rdfs:range <https://w3id.org/linkml/Any> .

obo:RO_0002324 a rdf:Property ;
  rdfs:range obo:BFO_0000002 .

obo:RO_0002326 a rdf:Property ;
  rdfs:label "contributes to"@en ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002329 , obo:RO_0002216 .

obo:RO_0002327 a rdf:Property ;
  rdfs:label "enables"@en ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002215 .

obo:RO_0002328 a rdf:Property ;
  rdfs:label "functionally related to"@en ;
  rdfs:range <https://w3id.org/linkml/Any> .

obo:RO_0002329 a rdf:Property ;
  rdfs:label "part of structure that is capable of"@en ;
  rdfs:comment "this relation holds between c and p when c is part of some c', and c' is capable of p." ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002328 .

obo:RO_0002331 a rdf:Property ;
  rdfs:label "involved in"@en ;
  rdfs:comment "c involved_in p if and only if c enables some process p', and p' is part of p" ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002431 .

obo:RO_0002332 a rdf:Property ;
  rdfs:label "regulates levels of"@en ;
  rdfs:comment "p regulates levels of c if p regulates some amount (PATO:0000070) of c" ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002328 .

obo:RO_0002333 a rdf:Property ;
  rdfs:label "enabled by"@en ;
  rdfs:comment "inverse of enables" ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002328 .

obo:RO_0002335 a rdf:Property ;
  rdfs:label "negatively regulated by"@en ;
  rdfs:comment "inverse of negatively regulates" ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002334 .

obo:RO_0002336 a rdf:Property ;
  rdfs:label "positively regulated by"@en ;
  rdfs:comment "inverse of positively regulates" ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002334 .

obo:RO_0002350 a rdf:Property ;
  rdfs:label "member of"@en ;
  rdfs:comment "is member of is a mereological relation between a item and a collection." ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:BFO_0000050 .

obo:RO_0002351 a rdf:Property ;
  rdfs:label "has member"@en ;
  rdfs:comment "has member is a mereological relation between a collection and an item." ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:BFO_0000051 .

obo:RO_0002352 a rdf:Property ;
  rdfs:label "input of"@en ;
  rdfs:comment "inverse of has input" ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002328 , obo:RO_0000056 .

obo:RO_0002353 a rdf:Property ;
  rdfs:label "output of"@en ;
  rdfs:comment "inverse of has output" ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002328 , obo:RO_0000056 .

obo:RO_0002354 a rdf:Property ;
  rdfs:label "formed as result of"@en ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002353 .

obo:RO_0002360 a rdf:Property ;
  rdfs:label "has dendrite location"@en ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002131 .

obo:RO_0002376 a rdf:Property ;
  rdfs:label "tributary of"@en ;
  rdfs:comment "x tributary_of y if and only if x a channel for the flow of a substance into y, where y is larger than x. If x and y are hydrographic features, then y is the main stem of a river, or a lake or bay, but not the sea or ocean. If x and y are anatomical, then y is a vein." ;
  rdfs:seeAlso <http://dbpedia.org/ontology/drainsTo> , <http://en.wikipedia.org/wiki/Tributary> ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002375 .

obo:RO_0002377 a rdf:Property ;
  rdfs:label "distributary of"@en ;
  rdfs:comment "x distributary_of y if and only if x is capable of channeling the flow of a substance to y, where y channels less of the substance than x" ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002375 .

obo:RO_0002378 a rdf:Property ;
  rdfs:label "anabranch of"@en ;
  rdfs:comment "x anabranch_of y if x is a distributary of y (i.e. it channels a from a larger flow from y) and x ultimately channels the flow back into y." ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002377 .

obo:RO_0002379 a rdf:Property ;
  rdfs:label "spatially coextensive with"@en ;
  rdfs:comment "x spatially_coextensive_with y if and inly if x and y have the same location" ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002131 .

obo:RO_0002380 a rdf:Property ;
  rdfs:label "branching part of"@en ;
  rdfs:comment "x is a branching part of y if and only if x is part of y and x is connected directly or indirectly to the main stem of y" ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002375 , obo:BFO_0000050 .

obo:RO_0002381 a rdf:Property ;
  rdfs:label "main stem of"@en ;
  rdfs:comment "x main_stem_of y if y is a branching structure and x is a channel that traces a linear path through y, such that x has higher capacity than any other such path." ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002375 .

obo:RO_0002382 a rdf:Property ;
  rdfs:label "proper distributary of"@en ;
  rdfs:comment "x proper_distributary_of y iff x distributary_of y and x does not flow back into y" ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002377 .

obo:RO_0002383 a rdf:Property ;
  rdfs:label "proper tributary of"@en ;
  rdfs:comment "x proper_tributary_of y iff x tributary_of y and x does not originate from y" ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002376 .

obo:RO_0002400 a rdf:Property ;
  rdfs:label "has direct input"@en ;
  rdfs:comment "p has direct input c iff c is a participant in p, c is present at the start of p, and the state of c is modified during p." ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002233 .

obo:RO_0002403 a rdf:Property ;
  rdfs:label "obsolete has indirect output" ;
  rdfs:comment """Likely to be obsoleted. See:
https://docs.google.com/document/d/1QMhs9J-P_q3o_rDh-IX4ZEnz0PnXrzLRVkI3vvz8NEQ/edit""" ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002234 .

obo:RO_0002404 a rdf:Property ;
  rdfs:label "causally downstream of"@en ;
  rdfs:comment "inverse of upstream of" ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002427 , obo:BFO_0000062 .

obo:RO_0002405 a rdf:Property ;
  rdfs:label "immediately causally downstream of"@en ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002404 , obo:RO_0002087 .

obo:RO_0002406 a rdf:Property ;
  rdfs:label "directly activates"@en ;
  rdfs:comment "p directly activates q if and only if p is immediately upstream of q and p is the realization of a function to increase the rate or activity of q" ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002629 .

obo:RO_0002407 a rdf:Property ;
  rdfs:label "indirectly activates"@en ;
  rdfs:comment "p directly activates q if and only if p is immediately upstream of q and p is the realization of a function to increase the rate or activity of q" ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002213 .

obo:RO_0002408 a rdf:Property ;
  rdfs:label "directly inhibits"@en ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002630 .

obo:RO_0002409 a rdf:Property ;
  rdfs:label "indirectly inhibits"@en ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002212 .

obo:RO_0002411 a rdf:Property ;
  rdfs:label "causally upstream of"@en ;
  rdfs:comment "p is causally upstream of q if and only if p precedes q and p and q are linked in a causal chain" ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002418 , obo:BFO_0000063 .

obo:RO_0002412 a rdf:Property ;
  rdfs:label "immediately causally upstream of"@en ;
  rdfs:comment "p is immediately causally upstream of q iff both (a) p immediately precedes q and (b) p is causally upstream of q. In addition, the output of p  must be an input of q." ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002411 , obo:RO_0002090 .

obo:RO_0002413 a rdf:Property ;
  rdfs:label "directly provides input for"@en ;
  rdfs:comment "p1 directly provides input for p2 iff there exists some c such that p1 has_output c and p2 has_input c" ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002414 , obo:RO_0002412 .

obo:RO_0002416 a rdf:Property ;
  rdfs:label "logical macro assertion"@en ;
  rdfs:comment "An assertion that involves at least one OWL object that is intended to be expanded into one or more logical axioms. The logical expansion can yield axioms expressed using any formal logical system, including, but not limited to OWL2-DL." ;
  rdfs:range xsd:string .

obo:RO_0002418 a rdf:Property ;
  rdfs:label "causally upstream of or within" ;
  rdfs:comment "p 'causally upstream or within' q iff (1) the end of p is before the end of q and (2) the execution of p exerts some causal influence over the outputs of q; i.e. if p was abolished or the outputs of p were to be modified, this would necessarily affect q." ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002501 .

obo:RO_0002419 a rdf:Property ;
  rdfs:label "annotation property cardinality"@en ;
  rdfs:comment "An assertion that holds between an OWL Annotation Property P and a non-negative integer N, with the interpretation: for any P(i j) it must be the case that | { k : P(i k) } | = N." ;
  rdfs:range xsd:nonNegativeInteger ;
  rdfs:subPropertyOf obo:RO_0002423 .

obo:RO_0002420 a rdf:Property ;
  rdfs:label "logical macro assertion on a class"@en ;
  rdfs:comment "A logical macro assertion whose domain is an IRI for a class" ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002416 .

obo:RO_0002421 a rdf:Property ;
  rdfs:label "logical macro assertion on a property"@en ;
  rdfs:comment "A logical macro assertion whose domain is an IRI for a property" ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002416 .

obo:RO_0002422 a rdf:Property ;
  rdfs:label "logical macro assertion on an object property"@en ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002421 .

obo:RO_0002423 a rdf:Property ;
  rdfs:label "logical macro assertion on an annotation property"@en ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002421 .

obo:RO_0002427 a rdf:Property ;
  rdfs:label "causally downstream of or within" ;
  rdfs:comment "inverse of causally upstream of or within" ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002501 .

obo:RO_0002428 a rdf:Property ;
  rdfs:label "involved in regulation of" ;
  rdfs:comment "c involved in regulation of p if c is involved in some 'p' and p' regulates some p" ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002431 , obo:RO_0002263 .

obo:RO_0002429 a rdf:Property ;
  rdfs:label "involved in positive regulation of" ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002428 .

obo:RO_0002430 a rdf:Property ;
  rdfs:label "involved in negative regulation of" ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002428 .

obo:RO_0002431 a rdf:Property ;
  rdfs:label "involved in or involved in regulation of" ;
  rdfs:comment "c involved in or regulates p if and only if either (i) c is involved in p or (ii) c is involved in regulation of p" ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002328 , obo:RO_0002500 , obo:RO_0002264 .

obo:RO_0002432 a rdf:Property ;
  rdfs:label "enables activity in" ;
  rdfs:comment "c executes activity in d if and only if c enables p and p occurs_in d" ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002328 .

obo:RO_0002433 a rdf:Property ;
  rdfs:label "contributes to morphology of" ;
  rdfs:comment "p contributes to morphology of w if and only if a change in the morphology of p entails a change in the morphology of w. Examples: every skull contributes to morphology of the head which it is a part of. Counter-example: nuclei do not generally contribute to the morphology of the cell they are part of, as they are buffered by cytoplasm." ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002131 .

obo:RO_0002448 a rdf:Property ;
  rdfs:label "molecularly controls" ;
  rdfs:comment "Holds between molecular entities a and b when the execution of a activates or inhibits the activity of b" ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002566 .

obo:RO_0002449 a rdf:Property ;
  rdfs:label "molecularly decreases activity of" ;
  rdfs:comment "Holds between molecules a and b if and only if a executes a process that directly diminishes a process executed by b." ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002448 .

obo:RO_0002450 a rdf:Property ;
  rdfs:label "molecularly increases activity of" ;
  rdfs:comment "Holds between molecules a and b if and only if a executes a process that directly activates a process executed by b." ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002448 .

obo:RO_0002452 a rdf:Property ;
  rdfs:label "has symptom" ;
  rdfs:comment "A relation that holds between a disease or an organism and a phenotype" ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002200 .

obo:RO_0002461 a rdf:Property ;
  rdfs:label "partner in" ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0000056 .

obo:RO_0002462 a rdf:Property ;
  rdfs:label "subject participant in" ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002461 .

obo:RO_0002463 a rdf:Property ;
  rdfs:label "target participant in" ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002461 .

obo:RO_0002472 a rdf:Property ;
  rdfs:label "is evidence for" ;
  rdfs:comment """A relationship between a piece of evidence a and some entity b, where b is  an information content entity, material entity or process, and 
the a supports either the existence of b, or the truth value of b.""" ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002616 .

obo:RO_0002473 a rdf:Property ;
  rdfs:label "composed primarily of" ;
  rdfs:comment "x composed_primarily_of y if and only if more than half of the mass of x is made from y or units of the same type as y." ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:BFO_0000051 .

obo:RO_0002474 a rdf:Property ;
  rdfs:label "dispositional interpretation" ;
  rdfs:comment "An assertion that holds between an OWL Object Property and a dispositional interpretation that elucidates how OWL Class Axioms or OWL Individuals that use this property are to be interpreted in a dispositional context. For example,  A binds B may be interpreted as A have a mutual disposition that is realized by binding to the other one." ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002422 .

obo:RO_0002475 a rdf:Property ;
  rdfs:label "has no connections with" ;
  rdfs:comment "A is has_no_connections_with B if there are no parts of A or B that have a connection with the other." ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002420 .

obo:RO_0002483 a rdf:Property ;
  rdfs:label "inherited annotation property" ;
  rdfs:range xsd:string .

obo:RO_0002484 a rdf:Property ;
  rdfs:label "curator guidance link" ;
  rdfs:comment "Connects an ontology entity (class, property, etc) to a URL from which curator guidance can be obtained. This assertion is inherited in the same manner as functional annotations (e.g. for GO, over SubClassOf and part_of)" ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002483 .

obo:RO_0002485 a rdf:Property ;
  rdfs:label "receives input from" ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002170 .

obo:RO_0002486 a rdf:Property ;
  rdfs:label "sends output to" ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002170 .

obo:RO_0002502 a rdf:Property ;
  rdfs:label "depends on" ;
  rdfs:seeAlso obo:BFO_0000169 ;
  rdfs:range <https://w3id.org/linkml/Any> .

obo:RO_0002503 a rdf:Property ;
  rdfs:label "towards" ;
  rdfs:comment "q towards e2 if and only if q is a relational quality such that q inheres-in some e, and e != e2 and q is dependent on e2" ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002502 .

obo:RO_0002504 a rdf:Property ;
  rdfs:label "always present in taxon" ;
  rdfs:comment "S always_present_in_taxon T if every fully formed member of taxon T has part some S, or is an instance of S" ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002175 .

obo:RO_0002505 a rdf:Property ;
  rdfs:label "has intermediate" ;
  rdfs:comment "p has intermediate c if and only if p has parts p1, p2 and p1 has output c, and p2 has input c" ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0000057 .

obo:RO_0002508 a rdf:Property ;
  rdfs:label "determines" ;
  rdfs:comment "inverse of determined by" ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002566 .

obo:RO_0002514 a rdf:Property ;
  rdfs:label "sequentially related to" ;
  rdfs:comment "A relation that holds between two entities that have the property of being sequences or having sequences. " ;
  rdfs:range <https://w3id.org/linkml/Any> .

obo:RO_0002515 a rdf:Property ;
  rdfs:label "sequentially adjacent to" ;
  rdfs:comment "x is sequentially adjacent to y iff x and y do not overlap and if there are no base units intervening between x and y" ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002527 .

obo:RO_0002516 a rdf:Property ;
  rdfs:label "has start sequence" ;
  rdfs:comment "x has start sequence y if the start of x is identical to the start of y, and x has y as a subsequence" ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002524 .

obo:RO_0002517 a rdf:Property ;
  rdfs:label "is start sequence of" ;
  rdfs:comment "inverse of has start sequence" ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002525 .

obo:RO_0002518 a rdf:Property ;
  rdfs:label "has end sequence" ;
  rdfs:comment "x has end sequence y if the end of x is identical to the end of y, and x has y as a subsequence" ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002524 .

obo:RO_0002519 a rdf:Property ;
  rdfs:label "is end sequence of" ;
  rdfs:comment "inverse of has end sequence" ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002525 .

obo:RO_0002520 a rdf:Property ;
  rdfs:label "is consecutive sequence of" ;
  rdfs:comment "x is a consecutive sequence of y iff x has subsequence y, and all the parts of x are made of zero or more repetitions of y or sequences as the same type as y." ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002524 .

obo:RO_0002521 a rdf:Property ;
  rdfs:label "is sequentially aligned with" ;
  rdfs:comment "x is sequentially aligned with if a significant portion bases of x and y correspond in terms of their base type and their relative ordering" ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002514 .

obo:RO_0002522 a rdf:Property ;
  rdfs:label "bounds sequence of" ;
  rdfs:comment "x bounds the sequence of y iff the upstream-most part of x is upstream of or coincident with the upstream-most part of y, and the downstream-most part of x is downstream of or coincident with the downstream-most part of y" ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002514 .

obo:RO_0002523 a rdf:Property ;
  rdfs:label "is bound by sequence of" ;
  rdfs:comment "inverse of bounds sequence of" ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002514 .

obo:RO_0002524 a rdf:Property ;
  rdfs:label "has subsequence" ;
  rdfs:comment "x has subsequence y iff all of the sequence parts of x are sequence parts of y" ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002522 , obo:RO_0002526 , obo:BFO_0000051 .

obo:RO_0002525 a rdf:Property ;
  rdfs:label "is subsequence of" ;
  rdfs:comment "inverse of has subsequence" ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002523 , obo:RO_0002526 , obo:BFO_0000050 .

obo:RO_0002526 a rdf:Property ;
  rdfs:label "overlaps sequence of" ;
  rdfs:comment "x overlaps the sequence of x if and only if x has a subsequence z and z is a subsequence of y." ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002514 , obo:RO_0002131 .

obo:RO_0002527 a rdf:Property ;
  rdfs:label "does not overlap sequence of" ;
  rdfs:comment "x does not overlaps the sequence of x if and only if there is no z such that x has a subsequence z and z is a subsequence of y." ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002514 .

obo:RO_0002528 a rdf:Property ;
  rdfs:label "is upstream of sequence of" ;
  rdfs:comment "inverse of downstream of sequence of" ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002527 .

obo:RO_0002529 a rdf:Property ;
  rdfs:label "is downstream of sequence of" ;
  rdfs:comment "x is downstream of the sequence of y iff either (1) x and y have sequence units, and all units of x are downstream of all units of y, or (2) x and y are sequence units, and x is either immediately downstream of y, or transitively downstream of y." ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002527 .

obo:RO_0002530 a rdf:Property ;
  rdfs:label "is immediately downstream of sequence of" ;
  rdfs:comment "x is immediately downstream of the sequence of y iff either (1) x and y have sequence units, and all units of x are downstream of all units of y, and x is sequentially adjacent to y, or (2) x and y are sequence units, in which case the immediately downstream relation is primitive and defined by context: for DNA bases, y would be adjacent and 5' to y" ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002529 , obo:RO_0002515 .

obo:RO_0002531 a rdf:Property ;
  rdfs:label "is immediately upstream of sequence of" ;
  rdfs:comment "inverse of immediately downstream of" ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002528 , obo:RO_0002515 .

obo:RO_0002535 a rdf:Property ;
  rdfs:label "temporal logical macro assertion on a class" ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002420 .

obo:RO_0002536 a rdf:Property ;
  rdfs:label "measurement property has unit" ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002423 .

obo:RO_0002537 a rdf:Property ;
  rdfs:label "has start time value" ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002535 .

obo:RO_0002538 a rdf:Property ;
  rdfs:label "has end time value" ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002535 .

obo:RO_0002539 a rdf:Property ;
  rdfs:label "start, days post fertilization" ;
  rdfs:comment "Count of number of days intervening between the start of the stage and the time of fertilization according to a reference model. Note that the first day of development has the value of 0 for this property." ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002537 .

obo:RO_0002540 a rdf:Property ;
  rdfs:label "end, days post fertilization" ;
  rdfs:comment "Count of number of days intervening between the end of the stage and the time of fertilization according to a reference model. Note that the first day of development has the value of 1 for this property." ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002538 .

obo:RO_0002541 a rdf:Property ;
  rdfs:label "start, years post birth" ;
  rdfs:comment "Count of number of years intervening between the start of the stage and the time of birth according to a reference model. Note that the first year of post-birth development has the value of 0 for this property, and the period during which the child is one year old has the value 1." ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002537 .

obo:RO_0002542 a rdf:Property ;
  rdfs:label "end, years post birth" ;
  rdfs:comment "Count of number of years intervening between the end of the stage and the time of birth according to a reference model. Note that the first year of post-birth development has the value of 1 for this property, and the period during which the child is one year old has the value 2" ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002538 .

obo:RO_0002543 a rdf:Property ;
  rdfs:label "start, months post birth" ;
  rdfs:comment "Count of number of months intervening between the start of the stage and the time of birth according to a reference model. Note that the first month of post-birth development has the value of 0 for this property, and the period during which the child is one month old has the value 1." ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002537 .

obo:RO_0002544 a rdf:Property ;
  rdfs:label "end, months post birth" ;
  rdfs:comment "Count of number of months intervening between the end of the stage and the time of birth according to a reference model. Note that the first month of post-birth development has the value of 1 for this property, and the period during which the child is one month old has the value 2" ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002538 .

obo:RO_0002545 a rdf:Property ;
  rdfs:label "month of gestation" ;
  rdfs:comment "Defines the start and end of a stage with a duration of 1 month, relative to either the time of fertilization or last menstrual period of the mother (to be clarified), counting from one, in terms of a reference model. Thus if month_of_gestation=3, then the stage is 2 month in." ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002535 .

obo:RO_0002546 a rdf:Property ;
  rdfs:label "has developmental stage marker" ;
  rdfs:comment "A relationship between a stage class and an anatomical structure or developmental process class, in which the stage is characterized by the appearance of the structure or the occurrence of the biological process" ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002535 .

obo:RO_0002547 a rdf:Property ;
  rdfs:label "start, days post coitum" ;
  rdfs:comment "Count of number of days intervening between the start of the stage and the time of coitum." ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002537 .

obo:RO_0002548 a rdf:Property ;
  rdfs:label "end, days post coitum" ;
  rdfs:comment "Count of number of days intervening between the end of the stage and the time of coitum." ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002538 .

obo:RO_0002549 a rdf:Property ;
  rdfs:label "start, weeks post birth" ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002537 .

obo:RO_0002550 a rdf:Property ;
  rdfs:label "end, weeks post birth" ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002538 .

obo:RO_0002551 a rdf:Property ;
  rdfs:label "has skeleton" ;
  rdfs:comment "A relation between a segment or subdivision of an organism and the maximal subdivision of material entities that provides structural support for that segment or subdivision." ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:BFO_0000051 .

obo:RO_0002558 a rdf:Property ;
  rdfs:label "has evidence" ;
  rdfs:comment "inverse of is evidence for" ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002616 .

obo:RO_0002559 a rdf:Property ;
  rdfs:label "causally influenced by" ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002506 .

obo:RO_0002560 a rdf:Property ;
  rdfs:label "is asymmetric relational form of process class" ;
  rdfs:comment "If Rel is the relational form of a process Pr, then it follow that: Rel(x,y) <-> exists p : Pr(p), x subject-partner-in p, y object-partner-in p" ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002562 .

obo:RO_0002561 a rdf:Property ;
  rdfs:label "is symmetric relational form of process class" ;
  rdfs:comment "If Rel is the relational form of a process Pr, then it follow that: Rel(x,y) <-> exists p : Pr(p), x partner-in p, y partner-in p" ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002562 .

obo:RO_0002562 a rdf:Property ;
  rdfs:label "is relational form of process class" ;
  rdfs:comment "R is the relational form of a process if and only if either (1) R is the symmetric relational form of a process or (2) R is the asymmetric relational form of a process" ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002594 .

obo:RO_0002566 a rdf:Property ;
  rdfs:label "causally influences" ;
  rdfs:comment "Holds between materal entities a and b if the activity of a is causally upstream of the activity of b, or causally upstream of a an activity that modifies b" ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002506 .

obo:RO_0002569 a rdf:Property ;
  rdfs:label "has branching part" ;
  rdfs:comment "inverse of branching part of" ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002375 .

obo:RO_0002571 a rdf:Property ;
  rdfs:label "lumen of" ;
  rdfs:comment "x lumen_of y iff x is the space or substance that is part of y and does not cross any of the inner membranes or boundaries of y that is maximal with respect to the volume of the convex hull." ;
  rdfs:range obo:BFO_0000040 ;
  rdfs:subPropertyOf obo:BFO_0000050 .

obo:RO_0002575 a rdf:Property ;
  rdfs:label "is direct form of" ;
  rdfs:comment "relation p is the direct form of relation q iff p is a subPropertyOf q, p does not have the Transitive characteristic, q does have the Transitive characteristic, and for all x, y: x q y -> exists z1, z2, ..., zn such that x p z1 ... z2n y" ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002422 .

obo:RO_0002576 a rdf:Property ;
  rdfs:label "skeleton of" ;
  rdfs:comment "inverse of has skeleton" ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:BFO_0000050 .

obo:RO_0002578 a rdf:Property ;
  rdfs:label "directly regulates" ;
  rdfs:comment "p 'directly regulates' q if and only if p and q are processes, and p regulates q, and q directly follows from p" ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002412 , obo:RO_0002211 .

obo:RO_0002579 a rdf:Property ;
  rdfs:label "is indirect form of" ;
  rdfs:comment "relation p is the indirect form of relation q iff p is a subPropertyOf q, and there exists some p' such that p' is the direct form of q, p' o p' -> p, and forall x,y : x q y -> either (1) x p y or (2) x p' y" ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002422 .

obo:RO_0002580 a rdf:Property ;
  rdfs:label "logical macro assertion on an axiom" ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002416 .

obo:RO_0002581 a rdf:Property ;
  rdfs:label "is a defining property chain axiom" ;
  rdfs:comment "If R <- P o Q is a defining property chain axiom, then it also holds that R -> P o Q. Note that this cannot be expressed directly in OWL" ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002580 .

obo:RO_0002582 a rdf:Property ;
  rdfs:label "is a defining property chain axiom where second argument is reflexive" ;
  rdfs:comment "If R <- P o Q is a defining property chain axiom, then (1) R -> P o Q holds and (2) Q is either reflexive or locally reflexive. A corollary of this is that P SubPropertyOf R." ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002581 .

obo:RO_0002584 a rdf:Property ;
  rdfs:label "has part structure that is capable of" ;
  rdfs:comment "s 'has part structure that is capable of' p if and only if there exists some part x such that s 'has part' x and x 'capable of' p" ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002595 , obo:RO_0002328 .

obo:RO_0002586 a rdf:Property ;
  rdfs:label "results in breakdown of" ;
  rdfs:comment "p results in breakdown of c if and only if the execution of p leads to c no longer being present at the end of p" ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002233 .

obo:RO_0002589 a rdf:Property ;
  rdfs:label "results in catabolism of" ;
  rdfs:comment "p results in catabolism of c if and only if p is a catabolic process, and the execution of p results in c being broken into smaller parts with energy being released." ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002586 .

obo:RO_0002590 a rdf:Property ;
  rdfs:label "results in disassembly of" ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002592 , obo:RO_0002586 .

obo:RO_0002591 a rdf:Property ;
  rdfs:label "results in remodeling of" ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002592 , obo:RO_0002233 .

obo:RO_0002592 a rdf:Property ;
  rdfs:label "results in organization of" ;
  rdfs:comment "p results in organization of c iff p results in the assembly, arrangement of constituent parts, or disassembly of c" ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0000057 .

obo:RO_0002594 a rdf:Property ;
  rdfs:label "is relational form of a class" ;
  rdfs:comment "An annotation property that connects an object property to a class, where the object property is derived from or a shortcut property for the class. The exact semantics of this annotation may vary on a case by case basis." ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002422 .

obo:RO_0002596 a rdf:Property ;
  rdfs:label "capable of regulating" ;
  rdfs:comment "Holds between c and p if and only if c is capable of some activity a, and a regulates p." ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002500 .

obo:RO_0002597 a rdf:Property ;
  rdfs:label "capable of negatively regulating" ;
  rdfs:comment "Holds between c and p if and only if c is capable of some activity a, and a negatively regulates p." ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002596 .

obo:RO_0002598 a rdf:Property ;
  rdfs:label "capable of positively regulating" ;
  rdfs:comment "Holds between c and p if and only if c is capable of some activity a, and a positively regulates p." ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002596 .

obo:RO_0002599 a rdf:Property ;
  rdfs:label "capable of inhibiting or preventing pathological process" ;
  rdfs:comment "Holds between a material entity c and a pathological process p if and only if c is capable of some activity a, where a inhibits p." ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002597 .

obo:RO_0002600 a rdf:Property ;
  rdfs:label "capable of upregulating or causing pathological process" ;
  rdfs:comment "Holds between a material entity c and a pathological process p if and only if c is capable of some activity a, where a negatively regulates p." ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002598 .

obo:RO_0002601 a rdf:Property ;
  rdfs:label "logical macro assertion involving identity" ;
  rdfs:comment "A shortcut relationship that holds between two entities based on their identity criteria" ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002416 .

obo:RO_0002602 a rdf:Property ;
  rdfs:label "in approximate one to one relationship with" ;
  rdfs:comment "A shortcut relationship between two entities x and y1, such that the intent is that the relationship is functional and inverse function, but there is no guarantee that this property holds." ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002601 .

obo:RO_0002603 a rdf:Property ;
  rdfs:label "is approximately equivalent to" ;
  rdfs:comment "x is approximately equivalent to y if it is the case that x is equivalent, identical or near-equivalent to y" ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002602 .

obo:RO_0002604 a rdf:Property ;
  rdfs:label "is opposite of" ;
  rdfs:comment "x is the opposite of y if there exists some distance metric M, and there exists no z such as M(x,z) <= M(x,y) or M(y,z) <= M(y,x)." ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002602 .

obo:RO_0002605 a rdf:Property ;
  rdfs:label "is indistinguishable from" ;
  rdfs:comment "x is indistinguishable from y if there exists some distance metric M, and there exists no z such as M(x,z) <= M(x,y) or M(y,z) <= M(y,x)." ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002603 .

obo:RO_0002606 a rdf:Property ;
  rdfs:label "is substance that treats" ;
  rdfs:comment "c is a substance that treats d if c is a material entity (such as a small molecule or compound) and d is a pathological process, phenotype or disease, and c is capable of some activity that negative regulates or decreases the magnitude of d." ;
  rdfs:seeAlso <https://code.google.com/p/obo-relations/issues/detail?id=46> ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002599 .

obo:RO_0002607 a rdf:Property ;
  rdfs:label "is marker for" ;
  rdfs:comment "c is marker for d iff the presence or occurrence of d is correlated with the presence of occurrence of c, and the observation of c is used to infer the presence or occurrence of d. Note that this does not imply that c and d are in a direct causal relationship, as it may be the case that there is a third entity e that stands in a direct causal relationship with c and d." ;
  rdfs:range <https://w3id.org/linkml/Any> .

obo:RO_0002611 a rdf:Property ;
  rdfs:label "evidential logical macro assertion on an axiom" ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002580 .

obo:RO_0002612 a rdf:Property ;
  rdfs:label "axiom has evidence" ;
  rdfs:comment "A relationship between a sentence and an instance of a piece of evidence in which the evidence supports the axiom" ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002611 .

obo:RO_0002613 a rdf:Property ;
  rdfs:label "axiom contradicted by evidence" ;
  rdfs:comment "A relationship between a sentence and an instance of a piece of evidence in which the evidence contradicts the axiom" ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002611 .

obo:RO_0002614 a rdf:Property ;
  rdfs:label "is evidence with support from" ;
  rdfs:comment "A relationship between a piece of evidence and an entity that plays a role in supporting that evidence." ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002616 .

obo:RO_0002616 a rdf:Property ;
  rdfs:label "related via evidence or inference to" ;
  rdfs:range <https://w3id.org/linkml/Any> .

obo:RO_0002617 a rdf:Property ;
  rdfs:label "is representative IRI for equivalence set" ;
  rdfs:comment "this property relates an IRI to the xsd boolean value \"True\" if the IRI is intended to be the representative IRI for a collection of classes that are mutually equivalent." ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002601 .

obo:RO_0002629 a rdf:Property ;
  rdfs:label "directly positively regulates" ;
  rdfs:comment "p 'directly positively regulates' q if and only if p and q are processes, and p positively regulates q, and q directly follows from p" ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002578 , obo:RO_0002213 .

obo:RO_0002630 a rdf:Property ;
  rdfs:label "directly negatively regulates" ;
  rdfs:comment "p 'directly negatively regulates' q if and only if p and q are processes, and p negatively regulates q, and q directly follows from p" ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002578 , obo:RO_0002212 .

obo:RO_0003002 a rdf:Property ;
  rdfs:label "represses expression of" ;
  rdfs:comment "Holds between protein a (a transcription factor) and DNA element b if and only if a diminishes the process of transcription of b." ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002449 .

obo:RO_0003003 a rdf:Property ;
  rdfs:label "increases expression of" ;
  rdfs:comment "Holds between protein a (a transcription factor) and DNA element b if and only if a activates the process of transcription of b." ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002450 .

obo:RO_0003302 a rdf:Property ;
  rdfs:label "causes or contributes to condition"@en ;
  rdfs:comment "A relationship between an entity (a genotype, genetic variation or environment) and a condition (a phenotype or disease) where the entity has some causal or contributing role that influences the condition." ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002410 .

obo:RO_0003303 a rdf:Property ;
  rdfs:label "causes condition"@en ;
  rdfs:comment "A relationship between an entity (a genotype, genetic variation or environment) and a condition (a phenotype or disease) where the entity has a causal role for the condition." ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0003302 .

obo:RO_0003304 a rdf:Property ;
  rdfs:label "contributes to condition"@en ;
  rdfs:comment "A relationship between an entity (a genotype, genetic variation or environment) and a condition (a phenotype or disease) where the entity has some contributing role in the manifestation of the condition." ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0003302 .

obo:RO_0003305 a rdf:Property ;
  rdfs:label "contributes to severity of condition"@en ;
  rdfs:comment "A relationship between an entity (a genotype, genetic variation or environment) and a condition (a phenotype or disease) where the entity influences the severity with which a condition manifests in an individual." ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0003304 .

obo:RO_0003306 a rdf:Property ;
  rdfs:label "contributes to frequency of condition"@en ;
  rdfs:comment "A relationship between an entity (a genotype, genetic variation or environment) and a condition (a phenotype or disease) where the entity influences the frequency of the condition in a population." ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0003304 .

obo:RO_0003307 a rdf:Property ;
  rdfs:label "is preventative for condition"@en ;
  rdfs:comment "A relationship between an entity (a genotype, genetic variation or environment) and a condition (a phenotype or disease) where the entity prevents or reduces the severity of a condition." ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002410 .

obo:RO_0003308 a rdf:Property ;
  rdfs:label "correlated with condition"@en ;
  rdfs:comment "A relationship between an entity and a condition (phenotype or disease) with which it exhibits a statistical dependence relationship." ;
  rdfs:range <https://w3id.org/linkml/Any> .

obo:UPHENO_0000001 a rdf:Property ;
  rdfs:label "has phenotype affecting" ;
  rdfs:range <https://w3id.org/linkml/Any> .

<http://purl.obolibrary.org/obo/ncbitaxon#has_rank> a rdf:Property ;
  rdfs:label "has_rank" ;
  rdfs:comment """
A metadata relation between a class and its taxonomic rank (eg species, family)
""" ;
  rdfs:range xsd:string .

<http://purl.obolibrary.org/obo/ro/subsets#ro-eco> a rdf:Property ;
  rdfs:label "eco subset" ;
  rdfs:range xsd:string .

<http://purl.org/obo/owl/obo#towards> a rdf:Property ;
  rdfs:label "towards"@en ;
  rdfs:comment "relation binding a relational quality or disposition to the relevant type of entity" ;
  rdfs:range <https://w3id.org/linkml/Any> .
