PREFIX obo: <http://purl.obolibrary.org/obo/>
PREFIX rdf: <http://www.w3.org/1999/02/22-rdf-syntax-ns#>
PREFIX rdfs: <http://www.w3.org/2000/01/rdf-schema#>
PREFIX xsd: <http://www.w3.org/2001/XMLSchema#>

obo:ExO_0000117 a rdfs:Class ;
  rdfs:label "never smoker" ;
  rdfs:comment "A person who was not smoking at the time of the interview and has smoked less than 100 cigarettes in their life." ;
  rdfs:subClassOf obo:ExO_0000113 .

obo:BFO_0000050 a rdf:Property ;
  rdfs:comment "For continuants: C part_of C' if and only if: given any c that instantiates C at a time t, there is some c' such that c' instantiates C' at time t, and c *part_of* c' at t. For processes: P part_of P' if and only if: given any p that instantiates P at a time t, there is some p' such that p' instantiates P' at time t, and p *part_of* p' at t. (Here *part_of* is the instance-level part-relation.)" ;
  rdfs:range <https://w3id.org/linkml/Any> .

obo:RO_0002434 a rdf:Property ;
  rdfs:label "interacts with" ;
  rdfs:range <https://w3id.org/linkml/Any> .

obo:ExO_0000106 a rdfs:Class ;
  rdfs:label "diet" ;
  rdfs:comment "The customary allowance of food and drink taken by a person or an animal from day to day, particularly one especially planned to meet specific requirements of the individual, including or excluding certain items of food; a prescribed course of eating and drinking in which the amount and kind of food, as well as the times at which it is to be taken, are regulated for therapeutic purposes or selected with reference to a particular state of health." ;
  rdfs:subClassOf obo:ExO_0000103 .

obo:ExO_0000156 a rdfs:Class ;
  rdfs:label "Samoan" ;
  rdfs:comment "A person having origins in any of the original peoples of Samoa." ;
  rdfs:subClassOf obo:ExO_0000109 .

obo:ExO_0000005 a rdfs:Class ;
  rdfs:label "biological agent" ;
  rdfs:comment "An agent of biological origin." ;
  rdfs:subClassOf obo:ExO_0000000 .

<http://purl.obolibrary.org/obo/exo#interacts_with_an_exposure_receptor_via> a rdf:Property ;
  rdfs:label "interacts_with_an_exposure_receptor_via" ;
  rdfs:range <https://w3id.org/linkml/Any> .

obo:ExO_0000146 a rdfs:Class ;
  rdfs:label "Inuit" ;
  rdfs:comment "A general term for a group of culturally similar indigenous peoples inhabiting the Arctic regions of Canada, Greenland, Russia and the United States. In Alaska, the term Eskimo is commonly used, because it includes both Yupik and Inupiat, while Inuit is not accepted as a collective term. In Canada and Greenland, the term Eskimo has fallen out of favor, as it is considered pejorative by the natives and has been replaced by the term Inuit." ;
  rdfs:subClassOf obo:ExO_0000109 .

obo:ExO_0000040 a rdfs:Class ;
  rdfs:label "cultural background" ;
  rdfs:comment "A social characteristic about or relating to the arts and manners favored or practiced by a group." ;
  rdfs:subClassOf obo:ExO_0000039 .

obo:ExO_0000034 a rdfs:Class ;
  rdfs:label "occupation" ;
  rdfs:comment "An individual attribute that is the usual or principal work or business of an individual." ;
  rdfs:subClassOf obo:ExO_0000089 .

obo:ExO_0000168 a rdfs:Class ;
  rdfs:label "static exposure" ;
  rdfs:comment "A sustained chemical exposure in which the exposed subject or sample is in a non-flowing, stagnant environment with the stressor." ;
  rdfs:subClassOf obo:ExO_0000167 .

obo:ExO_0000045 a rdfs:Class ;
  rdfs:label "tissue" ;
  rdfs:comment "Anatomical structure, which consists of similarly specialized cells and intercellular matrix, aggregated according to genetically determined spatial relationships. Examples: epithelium, muscle tissue, connective tissue, neural tissue, lymphoid tissue." .

obo:ExO_0000061 a rdfs:Class ;
  rdfs:label "subcutaneous tissue" ;
  rdfs:comment "Superficial fascia." .

<http://purl.obolibrary.org/obo/exo#targeted_to> a rdf:Property ;
  rdfs:range <https://w3id.org/linkml/Any> .

obo:ExO_0000163 a rdfs:Class ;
  rdfs:label "passive inhalation of the ambient environment route" ;
  rdfs:comment "An exposure route in which a subject or sample comes in contact with a stressor by breathing the ambient air containing this stressor." ;
  rdfs:subClassOf obo:ExO_0000057 , obo:ExO_0000162 .

obo:ExO_0000012 a rdfs:Class ;
  rdfs:label "habitat degradation" ;
  rdfs:comment "An ecological perturbation that results from the deterioration of  an ecological or environmental area that is inhabited by a particular species of animal, plant or other type of organism." ;
  rdfs:subClassOf obo:ExO_0000007 .

obo:ExO_0000152 a rdfs:Class ;
  rdfs:label "Native Hawaiian" ;
  rdfs:comment "A person having origins in any of the original peoples of Hawaii." ;
  rdfs:subClassOf obo:ExO_0000109 .

obo:ExO_0000050 a rdfs:Class ;
  rdfs:label "temporal quality" ;
  rdfs:comment "A quality of a single process inhering in a bearer by virtue of the bearer's occurrence." .

obo:ExO_0000157 a rdfs:Class ;
  rdfs:label "Vietnamese" ;
  rdfs:comment "A person having origins in any of the original peoples of Vietnam." ;
  rdfs:subClassOf obo:ExO_0000109 .

obo:ExO_0000141 a rdfs:Class ;
  rdfs:label "Cuban-American" ;
  rdfs:comment "Denotes a person from or of Cuba or an American citizen of Cuban descent." ;
  rdfs:subClassOf obo:ExO_0000109 .

obo:ExO_0000023 a rdfs:Class ;
  rdfs:label "process" ;
  rdfs:comment "The act of taking something through an established and usually routine set of procedures to convert it from one form to another." ;
  rdfs:subClassOf obo:ExO_0000016 .

obo:ExO_0000135 a rdfs:Class ;
  rdfs:label "Asian" ;
  rdfs:comment "A person having origins in any of the original peoples of the Far East, Southeast Asia, or the Indian subcontinent, including for example, Cambodia, China, India, Japan, Korea, Malaysia, Pakistan, the Philippine Islands, Thailand, and Vietnam." ;
  rdfs:subClassOf obo:ExO_0000109 .

obo:ExO_0000044 a rdfs:Class ;
  rdfs:label "organ" ;
  rdfs:comment "Anatomical structure, which consists of the maximal set of organ parts so connected to one another that together they constitute a unit of macroscopic anatomy, structurally distinct from other such units. Examples: femur, biceps, liver, heart, skin, tracheobronchial tree, ovary." .

obo:ExO_0000038 a rdfs:Class ;
  rdfs:label "health status" ;
  rdfs:comment "The condition of an organism in all aspects (e.g., functional or metabolic efficiency)." ;
  rdfs:subClassOf obo:ExO_0000089 .

obo:ExO_0000136 a rdfs:Class ;
  rdfs:label "Asian Indian" ;
  rdfs:comment "A person having origins in the original peoples of the Indian sub-continent." ;
  rdfs:subClassOf obo:ExO_0000109 .

obo:EXO_0000162 a rdfs:Class ;
  rdfs:label "intramuscular injection route" ;
  rdfs:comment "An injection route of exposure which is administered into a muscle." ;
  rdfs:subClassOf obo:ExO_0000060 .

obo:ExO_0000128 a rdfs:Class ;
  rdfs:label "subjects with disease or phenotype" ;
  rdfs:comment "Study subjects with a disease or phenotype as indicated." ;
  rdfs:subClassOf obo:ExO_0000033 .

obo:ExO_0000072 a rdfs:Class ;
  rdfs:label "model" ;
  rdfs:comment "A representation." ;
  rdfs:subClassOf obo:ExO_0000064 .

<http://purl.obolibrary.org/obo/exo#characterizes> a rdf:Property ;
  rdfs:label "characterizes" ;
  rdfs:range <https://w3id.org/linkml/Any> .

obo:ExO_0000055 a rdfs:Class ;
  rdfs:label "exposure route" ;
  rdfs:comment "The way people, sample, or other living organisms come into contact with a stressor." .

obo:ExO_0000033 a rdfs:Class ;
  rdfs:label "human population" ;
  rdfs:comment "An exposure_receptor that is a group of Homo sapiens inhabiting a given area." ;
  rdfs:subClassOf obo:ExO_0000001 .

obo:ExO_0000145 a rdfs:Class ;
  rdfs:label "Hispanic" ;
  rdfs:comment "A person of Cuban, Mexican, Puerto Rican, South or Central American, or other Spanish culture or origin, regardless of race." ;
  rdfs:subClassOf obo:ExO_0000109 .

obo:ExO_0000066 a rdfs:Class ;
  rdfs:label "unit" ;
  rdfs:comment "A unit of measurement is a standardized quantity of a physical quality." .

obo:BFO_0000051 a rdf:Property ;
  rdfs:label "has_part" ;
  rdfs:range <https://w3id.org/linkml/Any> .

obo:ExO_0000073 a rdfs:Class ;
  rdfs:label "conceptual" ;
  rdfs:comment "A representation of a particular system or subject matter that may only be drawn on paper, described in words, or imagined in the mind." ;
  rdfs:subClassOf obo:ExO_0000072 .

obo:ExO_0000017 a rdfs:Class ;
  rdfs:label "location" ;
  rdfs:comment "A spatial quality inhering in a bearer by virtue of the bearer's spatial location relative to other objects in the vicinity." ;
  rdfs:subClassOf obo:ExO_0000002 , obo:ExO_0000088 .

<http://purl.obolibrary.org/obo/exo#interacts_with_an_exposure_stressor_via> a rdf:Property ;
  rdfs:label "interacts_with_an_exposure stressor_via" ;
  rdfs:range <https://w3id.org/linkml/Any> .

obo:ExO_0000083 a rdfs:Class ;
  rdfs:label "exposure medium" ;
  rdfs:comment "An exposure medium is a substance through which something else is transmitted or carried during an exposure." .

obo:ExO_0000098 a rdfs:Class ;
  rdfs:label "region" ;
  rdfs:comment "An area or portion of something with more or less definite boundaries designed or specified according to some established biological, administrative, economic, demographic, etc. criteria." ;
  rdfs:subClassOf obo:ExO_0000096 .

obo:ExO_0000088 a rdfs:Class ;
  rdfs:label "spatial quality" ;
  rdfs:comment "Of or relating to space or components within space." .

obo:ExO_0000051 a rdfs:Class ;
  rdfs:label "frequency" ;
  rdfs:comment "A physical quality, which inheres in a bearer by virtue of the number of the bearer's repetitive actions in a particular time." ;
  rdfs:subClassOf obo:ExO_0000050 .

obo:ExO_0000002 a rdfs:Class ;
  rdfs:label "exposure event" ;
  rdfs:comment "An interaction between an exposure stressor and an exposure_receptor." ;
  rdfs:subClassOf obo:BFO_0000015 .

obo:ExO_0000011 a rdfs:Class ;
  rdfs:label "biomechanical agent" ;
  rdfs:comment "A mechanical agent applied to biological systems, such as humans, animals, plants, organs, and cells" ;
  rdfs:subClassOf obo:ExO_0000000 .

obo:ExO_0000158 a rdfs:Class ;
  rdfs:label "White" ;
  rdfs:comment "A person having origins in any of the original peoples of Europe, the Middle East, or North Africa." ;
  rdfs:subClassOf obo:ExO_0000109 .

obo:ExO_0000169 a rdfs:Class ;
  rdfs:label "static renewal exposure" ;
  rdfs:comment "A sustained chemical exposure in which the exposed subject or sample is in an environment with the stressor is refreshed or renewed periodically." ;
  rdfs:subClassOf obo:ExO_0000167 .

obo:ExO_0000062 a rdfs:Class ;
  rdfs:label "muscle" ;
  rdfs:comment "The contractile tissue of animals and is derived from the mesodermal layer of embryonic germ cells." .

obo:ExO_0000022 a rdfs:Class ;
  rdfs:label "exposure stimulus" ;
  rdfs:comment "Any agent, entity, activity, or event that causally effects an organism and interacts with an exposure receptor during an exposure event." .

obo:ExO_0000134 a rdfs:Class ;
  rdfs:label "American Indian" ;
  rdfs:comment "Denotes a person having origins in one of the indigenous peoples of North America, who lived on the continent prior to the European colonization. The term includes individuals belonging to a large number of tribes, states, and ethnic groups, many of them still enduring as communities." ;
  rdfs:subClassOf obo:ExO_0000109 .

obo:ExO_0000077 a rdfs:Class ;
  rdfs:label "biological response" ;
  rdfs:subClassOf obo:ExO_0000003 .

<http://purl.obolibrary.org/obo/exo#is_associated_with> a rdf:Property ;
  rdfs:label "is_associated_with" ;
  rdfs:range <https://w3id.org/linkml/Any> .

obo:ExO_0000120 a rdfs:Class ;
  rdfs:label "cohort" ;
  rdfs:comment "A group of individuals, identified by a common characteristic." ;
  rdfs:subClassOf obo:ExO_0000033 .

obo:ExO_0000056 a rdfs:Class ;
  rdfs:label "ingestion route" ;
  rdfs:comment "An exposure route in which a subject or sample comes in contact with a stressor by swallowing the stressor or a substance containing the stressor." ;
  rdfs:subClassOf obo:ExO_0000165 .

obo:ExO_0000147 a rdfs:Class ;
  rdfs:label "Japanese" ;
  rdfs:comment "A person having origins in any of the original peoples of Japan." ;
  rdfs:subClassOf obo:ExO_0000109 .

obo:ExO_0000039 a rdfs:Class ;
  rdfs:label "social characteristic" ;
  rdfs:comment "An individual attribute human society and its modes of organization." ;
  rdfs:subClassOf obo:ExO_0000089 .

obo:ExO_0000167 a rdfs:Class ;
  rdfs:label "sustained exposure" ;
  rdfs:comment "An exposure in which the contact with the stressor is uninterrupted over an extended period of time." ;
  rdfs:subClassOf obo:ExO_0000172 .

obo:ExO_0000144 a rdfs:Class ;
  rdfs:label "Guamanian" ;
  rdfs:comment "Denotes inhabitants of Guam, an island in the North Pacific Ocean, about three-quarters of the way from Hawaii to the Philippines, south of the Northern Mariana Islands." ;
  rdfs:subClassOf obo:ExO_0000109 .

obo:ExO_0000076 a rdfs:Class ;
  rdfs:label "dose" ;
  rdfs:comment "The total quantity or strength of a substance administered at one time." ;
  rdfs:subClassOf obo:ExO_0000003 , obo:ExO_0000065 .

obo:ExO_0000121 a rdfs:Class ;
  rdfs:label "controls for disease or phenotype" ;
  rdfs:comment "Study subjects who serve as controls (i.e., lack the characteristics of a disease or phenotype) in a research study as compared to study subjects with a disease or phenotype as indicated." ;
  rdfs:subClassOf obo:ExO_0000033 .

obo:ExO_0000151 a rdfs:Class ;
  rdfs:label "Mexican-American" ;
  rdfs:comment "Denotes an american citizen of Mexican descent." ;
  rdfs:subClassOf obo:ExO_0000109 .

obo:ExO_0000099 a rdfs:Class ;
  rdfs:label "US State" ;
  rdfs:comment "One of the fifty states which is a member of the federation known as the United States of America. Other US geographic areas, such as Puerto Rico and the District of Columbia, are essentially equivalent to State when used in an address." ;
  rdfs:subClassOf obo:ExO_0000096 .

obo:ExO_0000140 a rdfs:Class ;
  rdfs:label "Cuban" ;
  rdfs:comment "A person of Cuban culture or origin, regardless of race." ;
  rdfs:subClassOf obo:ExO_0000109 .

obo:ExO_0000021 a rdfs:Class ;
  rdfs:label "endogenous" ;
  rdfs:comment "Substances or processes that originate within an organism or a system." ;
  rdfs:subClassOf obo:ExO_0000017 .

obo:ExO_0000010 a rdfs:Class ;
  rdfs:label "air transport path" ;
  rdfs:comment "A transport path that allows a stressor to interact with a receptor via air." ;
  rdfs:subClassOf obo:ExO_0000004 .

obo:ExO_0000137 a rdfs:Class ;
  rdfs:label "Central or South American" ;
  rdfs:comment "A person of Central or South American culture or origin." ;
  rdfs:subClassOf obo:ExO_0000109 .

obo:ExO_0000162 a rdfs:Class ;
  rdfs:label "ambient terrestrial environment route" ;
  rdfs:comment "An ambient environment in which the surroundings are terrestrial." ;
  rdfs:subClassOf obo:ExO_0000160 .

obo:ExO_0000087 a rdfs:Class ;
  rdfs:label "exposure intervention" ;
  rdfs:comment "The act or fact of interfering so as to modify." ;
  rdfs:subClassOf obo:ExO_0000003 .

obo:ExO_0000003 a rdfs:Class ;
  rdfs:label "exposure outcome" ;
  rdfs:comment "Entity that results from the interaction between and exposure_receptor and an exposure stressor during an exposure event." .

obo:ExO_0000065 a rdfs:Class ;
  rdfs:label "intensity" ;
  rdfs:comment "A quality inhering in a bearer by virtue of the bearer possessing or displaying a distinctive feature in type or degree or effect or force." .

obo:ExO_0000170 a rdfs:Class ;
  rdfs:label "dynamic exposure" ;
  rdfs:comment "A sustained chemical exposure in which the exposed subject or sample is in an environment where the stressor is constantly refreshed or renewed." ;
  rdfs:subClassOf obo:ExO_0000167 .

obo:ExO_0000155 a rdfs:Class ;
  rdfs:label "Puerto Rican" ;
  rdfs:comment "A person of Puerto Rican descent." ;
  rdfs:subClassOf obo:ExO_0000109 .

obo:ExO_0000028 a rdfs:Class ;
  rdfs:label "water transport path" ;
  rdfs:comment "An exposure transport path involving the interaction of an exposure_receptor with an exposure stressor via water." ;
  rdfs:subClassOf obo:ExO_0000004 .

obo:ExO_0000110 a rdfs:Class ;
  rdfs:label "sex" ;
  rdfs:comment "The assemblage of physical properties or qualities by which male is distinguished from female; the physical difference between male and female; the distinguishing peculiarity of male or female." ;
  rdfs:subClassOf obo:ExO_0000103 .

obo:ExO_0000094 a rdfs:Class ;
  rdfs:label "medicinal stressor source" ;
  rdfs:comment "A drug product that contains one or more active and/or inactive ingredients; it is intended to treat, prevent or alleviate the symptoms of disease. This term does not refer to the individual ingredients that make up the product." ;
  rdfs:subClassOf obo:ExO_0000016 .

obo:ExO_0000054 a rdfs:Class ;
  rdfs:label "duration" ;
  rdfs:comment "Amount of time during which an event persists." ;
  rdfs:subClassOf obo:ExO_0000050 .

obo:ExO_0000032 a rdfs:Class .

obo:ExO_0000095 a rdfs:Class ;
  rdfs:label "dietary stressor source" ;
  rdfs:comment "The customary allowance of food and drink taken by a person or an animal from day to day, particularly one especially planned to meet specific requirements of the individual, including or excluding certain items of food; a prescribed course of eating and drinking in which the amount and kind of food, as well as the times at which it is to be taken, are regulated for therapeutic purposes or selected with reference to a particular state of health." ;
  rdfs:subClassOf obo:ExO_0000016 .

obo:ExO_0000133 a rdfs:Class ;
  rdfs:label "Alaska Native" ;
  rdfs:comment "Denotes a person having origins in any indigenous people of Alaska and their descendants and who maintains tribal affiliation, or community or cultural attachment. The concept refers to population subgroups such as Eskimos, Aleuts, Inupiat, Yupik, Alutiiq, Egegik,and Pribilovian, Alaskan Athabascan, Tlingit, and Haida. The concept refers also to individuals who classify themselves as such." ;
  rdfs:subClassOf obo:ExO_0000109 .

obo:ExO_0000130 a rdfs:Class ;
  rdfs:label "veterans" ;
  rdfs:comment "Former members of the armed services." ;
  rdfs:subClassOf obo:ExO_0000033 .

obo:ExO_0000004 a rdfs:Class ;
  rdfs:label "exposure transport path" ;
  rdfs:comment "A exposure transport path is the course an agent takes from the source to the target." .

obo:ExO_0000166 a rdfs:Class ;
  rdfs:label "gavage route" ;
  rdfs:comment "An exposure route in which a subject or sample comes in contact with a stressor that was directly administered into the stomach." ;
  rdfs:subClassOf obo:ExO_0000165 .

obo:ExO_0000043 a rdfs:Class ;
  rdfs:label "anatomy" ;
  rdfs:comment "The individual attribute describing the structure of a living organism." ;
  rdfs:subClassOf obo:ExO_0000089 , obo:ExO_0000101 .

obo:ExO_0000029 a rdfs:Class ;
  rdfs:label "soil transport path" ;
  rdfs:comment "An exposure transport path involving the interaction of an exposure_receptor with an exposure stressor via soil." ;
  rdfs:subClassOf obo:ExO_0000004 .

obo:ExO_0000105 a rdfs:Class ;
  rdfs:label "body mass index" ;
  rdfs:comment "A general indicator of the body fat an individual is carrying based upon the ratio of weight to height." ;
  rdfs:subClassOf obo:ExO_0000103 .

obo:ExO_0000159 a rdfs:Class ;
  rdfs:label "maternal" ;
  rdfs:comment "A route by which an exposure to a pregnant female causes an outcome in the fetus that might be observed long after birth" ;
  rdfs:subClassOf obo:ExO_0000055 .

obo:BFO_0000015 a rdfs:Class ;
  rdfs:label "process" .

obo:ExO_0000018 a rdfs:Class ;
  rdfs:label "exogenous" ;
  rdfs:comment "Substances or processes that originate outside of an organism or a system." ;
  rdfs:subClassOf obo:ExO_0000017 .

obo:ExO_0000148 a rdfs:Class ;
  rdfs:label "Korean" ;
  rdfs:comment "A person having origins in any of the original peoples of Korea." ;
  rdfs:subClassOf obo:ExO_0000109 .

obo:ExO_0000090 a rdfs:Class ;
  rdfs:label "method" ;
  rdfs:comment "The protocol for an assay." .

obo:ExO_0000008 a rdfs:Class ;
  rdfs:label "physical agent" ;
  rdfs:comment "An agent as a source of energy that may cause injury or disease (e.g., noise, vibration, radiation, temperature extremes)." ;
  rdfs:subClassOf obo:ExO_0000000 .

obo:ExO_0000127 a rdfs:Class ;
  rdfs:label "study subjects" ;
  rdfs:comment "Persons who are observed, analyzed, examined, investigated, experimented upon, or/and treated in the course of a particular study." ;
  rdfs:subClassOf obo:ExO_0000033 .

obo:ExO_0000116 a rdfs:Class ;
  rdfs:label "former smoker" ;
  rdfs:comment "A person who was not smoking at the time of the interview but has smoked at least 100 cigarettes in their life." ;
  rdfs:subClassOf obo:ExO_0000113 .

obo:ExO_0000109 a rdfs:Class ;
  rdfs:label "race" ;
  rdfs:comment "An arbitrary classification of a taxonomic group that is a division of a species. It usually arises as a consequence of geographical isolation within a species and is characterized by shared heredity, physical attributes and behavior, and in the case of humans, by common history, nationality, or geographic distribution." ;
  rdfs:subClassOf obo:ExO_0000103 .

obo:EXO_0000161 a rdfs:Class ;
  rdfs:label "subcutaneous injection route" ;
  rdfs:comment "An injection route of exposure which is administered under the skin." ;
  rdfs:subClassOf obo:ExO_0000060 .

obo:ExO_0000122 a rdfs:Class ;
  rdfs:label "fetuses" ;
  rdfs:comment "An unborn or unhatched vertebrate in the later stages of development showing the main recognizable features of the mature being." ;
  rdfs:subClassOf obo:ExO_0000033 .

obo:ExO_0000020 a rdfs:Class ;
  rdfs:label "outdoor" ;
  rdfs:comment "An exogenous location that is happening or arising or located outside" ;
  rdfs:subClassOf obo:ExO_0000017 .

obo:ExO_0000070 a rdfs:Class ;
  rdfs:label "time" ;
  rdfs:comment "An exposure quality in which events occur in sequence." ;
  rdfs:subClassOf obo:ExO_0000050 .

obo:ExO_0000080 a rdfs:Class ;
  rdfs:label "symptom" ;
  rdfs:comment "A symptom is a perceived change in function, sensation, loss, disturbance or appearance reported by a patient indicative of a disease." ;
  rdfs:subClassOf obo:ExO_0000077 .

obo:ExO_0000138 a rdfs:Class ;
  rdfs:label "Chicano" ;
  rdfs:comment "A term sometimes used interchangeably with Mexican-American to denote an American citizen of Mexican decent.  The term is a chosen identity of some Mexican-Americans in the United States." ;
  rdfs:subClassOf obo:ExO_0000109 .

obo:ExO_0000171 a rdfs:Class ;
  rdfs:label "repeated exposure" ;
  rdfs:comment "An exposure in which the contact with the stressor occurs more than once over a period of time, at intervals." ;
  rdfs:subClassOf obo:ExO_0000172 .

obo:ExO_0000019 a rdfs:Class ;
  rdfs:label "indoor" ;
  rdfs:comment "A location that is happening or arising or located inside some limits, or especially, some surface." ;
  rdfs:subClassOf obo:ExO_0000017 .

obo:ExO_0000059 a rdfs:Class ;
  rdfs:label "leaching" ;
  rdfs:comment "The extraction of certain materials from a carrier into a liquid (usually, but not always a solvent)." ;
  rdfs:subClassOf obo:ExO_0000055 .

obo:ExO_0000064 a rdfs:Class ;
  rdfs:label "assay" ;
  rdfs:comment "A planned process with the objective to produce information about some evaluant." .

obo:ExO_0000143 a rdfs:Class ;
  rdfs:label "Filipino" ;
  rdfs:comment "A person having origins in any of the original peoples of the Philippine Islands." ;
  rdfs:subClassOf obo:ExO_0000109 .

obo:ExO_0000075 a rdfs:Class ;
  rdfs:label "computational" ;
  rdfs:comment "A representation of a particular system or subject matter that is computer-derived." ;
  rdfs:subClassOf obo:ExO_0000072 .

obo:ExO_0000007 a rdfs:Class ;
  rdfs:label "ecological perturbation" ;
  rdfs:comment "An exposure stressor that is a change in the distributions, abundance and relations of organisms and their interactions with the environment." ;
  rdfs:subClassOf obo:ExO_0000000 .

obo:ExO_0000150 a rdfs:Class ;
  rdfs:label "Mexican" ;
  rdfs:comment "Denotes a person from or of Mexico." ;
  rdfs:subClassOf obo:ExO_0000109 .

obo:ExO_0000126 a rdfs:Class ;
  rdfs:label "pregnant females" ;
  rdfs:comment "Human females who are pregnant." ;
  rdfs:subClassOf obo:ExO_0000033 .

obo:ExO_0000093 a rdfs:Class ;
  rdfs:label "occupational stressor source" ;
  rdfs:comment "The origination of a stressor from the location of the principal work or business of an individual." ;
  rdfs:subClassOf obo:ExO_0000016 .

obo:ExO_0000053 a rdfs:Class ;
  rdfs:label "continuous" ;
  rdfs:comment "A quality of a single process inhering in a bearer by virtue of the bearer's being uninterrupted in time, sequence, substance, or extent." ;
  rdfs:subClassOf obo:ExO_0000051 .

obo:ExO_0000047 a rdfs:Class ;
  rdfs:label "biological molecules" ;
  rdfs:comment "Substances made up of atoms, such as proteins, nucleic acids, lipids and carbohydrates that are produced only by living organisms. Biological molecules are often referred to as macromolecules or biopolymers." .

obo:ExO_0000091 a rdfs:Class ;
  rdfs:label "residential environment stressor source" ;
  rdfs:comment "Of, or relating to, the area in which an individual or population lives, primarily describing the dwelling or shelter used for housing and the location immediately surrounding it" ;
  rdfs:subClassOf obo:ExO_0000016 .

obo:ExO_0000009 a rdfs:Class ;
  rdfs:label "psychosocial agent" ;
  rdfs:comment "An agent that interferes with one's psychological development in and interaction with a social environment." ;
  rdfs:subClassOf obo:ExO_0000000 .

obo:ExO_0000161 a rdfs:Class ;
  rdfs:label "ambient acquatic environment route" ;
  rdfs:comment "An ambient environment route in which the surroundings are water." ;
  rdfs:subClassOf obo:ExO_0000160 .

obo:ExO_0000025 a rdfs:Class ;
  rdfs:label "industrial process" ;
  rdfs:comment "A systematic series of mechanical or chemical operations that produce or manufacture something." ;
  rdfs:subClassOf obo:ExO_0000023 .

obo:ExO_0000031 a rdfs:Class ;
  rdfs:label "biosphere" ;
  rdfs:comment "MERGED DEFINITION:\\nTARGET DEFINITION: An exposure_receptor that is the global ecological system integrating all living beings and their relationships, including their interaction with the elements of the lithosphere, hydrosphere and atmosphere.\\n--------------------\\nSOURCE DEFINITION: An exposure_receptor that is the part of the environment that is made or modified by humans for use in human activities and human habitats." .

obo:ExO_0000111 a rdfs:Class ;
  rdfs:label "female" ;
  rdfs:comment "A person who belongs to the sex that normally produces ova. The term is used to indicate biological sex distinctions, or cultural gender role distinctions, or both." ;
  rdfs:subClassOf obo:ExO_0000110 .

obo:ExO_0000015 a rdfs:Class ;
  rdfs:label "poverty" ;
  rdfs:comment "A psychosocial agent that is a situation in which the level of living of an individual, family, or group is below the standard of the community. It is often related to a specific income level." ;
  rdfs:subClassOf obo:ExO_0000009 .

obo:ExO_0000154 a rdfs:Class ;
  rdfs:label "Pacific Islander" ;
  rdfs:comment "A person having origins in the original peoples of the Pacific Islands, but not Guam, Hawaii, the Mariana Islands or Samoa." ;
  rdfs:subClassOf obo:ExO_0000109 .

obo:ExO_0000014 a rdfs:Class ;
  rdfs:label "climate change" ;
  rdfs:comment "An ecological pertubation that is any significant change in measures of climate (such as temperature, precipitation, or wind) lasting for an extended period (decades or longer). It may result from natural factors such as changes in the sun's intensity, natural processes within the climate system such as changes in ocean circulation, or human activities." ;
  rdfs:subClassOf obo:ExO_0000007 .

obo:ExO_0000026 a rdfs:Class ;
  rdfs:label "agricultural process" ;
  rdfs:comment "The exposure process of producing food, feed, fiber and other desired products by cultivation of certain plants or raising domesticated animals (livestock)." ;
  rdfs:subClassOf obo:ExO_0000023 .

obo:ExO_0000165 a rdfs:Class ;
  rdfs:label "gastrointestinal tract route" ;
  rdfs:comment "An exposure route in which a subject or sample comes in contact with a stressor in the subject's gastrointestinal tract." ;
  rdfs:subClassOf obo:ExO_0000055 .

obo:ExO_0000042 a rdfs:Class ;
  rdfs:label "human individual" ;
  rdfs:comment "Being or characteristic of a single thing or person." ;
  rdfs:subClassOf obo:ExO_0000001 .

obo:ExO_0000048 a rdfs:Class ;
  rdfs:label "built environment" ;
  rdfs:comment "Human-made surroundings that provide the setting for human activity, ranging in scale from personal shelter and buildings to neighborhoods and cite, and can often include their supporting infrastructure, such as water supply or energy networks." .

obo:ExO_0000115 a rdfs:Class ;
  rdfs:label "current smoker" ;
  rdfs:comment "An adult who has smoked 100 cigarettes in his or her lifetime and who currently smokes cigarettes. Includes daily smokers and non-daily smokers (also known as occasional smokers)." ;
  rdfs:subClassOf obo:ExO_0000113 .

obo:ExO_0000160 a rdfs:Class ;
  rdfs:label "ambient environment route" ;
  rdfs:comment "An exposure route in which a subject or sample comes in contact with a stressor present in the subject or sample's direct surroundings." ;
  rdfs:subClassOf obo:ExO_0000055 .

obo:ExO_0000172 a rdfs:Class ;
  rdfs:label "exposure regimen" ;
  rdfs:comment "The pattern or schedule of an exposure event, including dose, frequency, and duration." .

obo:ExO_0000108 a rdfs:Class ;
  rdfs:label "physical activity" ;
  rdfs:comment "Any form of exercise or movement. Physical activity may include planned activity such as walking, running, basketball, or other sports. Physical activity may also include other daily activities such as household chores, yard work, walking the dog, etc." ;
  rdfs:subClassOf obo:ExO_0000103 .

obo:ExO_0000132 a rdfs:Class ;
  rdfs:label "African American" ;
  rdfs:comment "A person having origins in any of the Black racial groups of Africa. Terms such as \"Haitian\" or \"Negro\" can be used in addition to \"Black or African American\"." ;
  rdfs:subClassOf obo:ExO_0000109 .

obo:ExO_0000058 a rdfs:Class ;
  rdfs:label "absorption" ;
  rdfs:comment "The process of one material (absorbent) being retained by another (absorbate)." ;
  rdfs:subClassOf obo:ExO_0000055 .

obo:ExO_0000149 a rdfs:Class ;
  rdfs:label "Latino" ;
  rdfs:comment "A person of Cuban, Mexican, Puerto Rican, South or Central American, or other Spanish culture or origin, regardless of race." ;
  rdfs:subClassOf obo:ExO_0000109 .

obo:ExO_0000037 a rdfs:Class ;
  rdfs:label "lifestage" ;
  rdfs:comment "A individual attribute that is a particular period in the life of an organism." ;
  rdfs:subClassOf obo:ExO_0000089 .

obo:ExO_0000119 a rdfs:Class ;
  rdfs:label "children" ;
  rdfs:comment "Persons who are not yet adults. The specific cut-off age will vary by purpose." ;
  rdfs:subClassOf obo:ExO_0000033 .

obo:ExO_0000104 a rdfs:Class ;
  rdfs:label "alcohol consumption" ;
  rdfs:comment "Consumption of liquids containing ethanol, including the behaviors associated with drinking the alcohol." ;
  rdfs:subClassOf obo:ExO_0000103 .

obo:ExO_0000096 a rdfs:Class ;
  rdfs:label "country" ;
  rdfs:comment "A collective generic term that refers here to a wide variety of dependencies, areas of special sovereignty, uninhabited islands, and other entities in addition to the traditional countries or independent states." ;
  rdfs:subClassOf obo:ExO_0000017 .

obo:ExO_0000067 a rdfs:Class ;
  rdfs:label "measurement" ;
  rdfs:comment "A measurement is an information entity that is a recording of the output of a measurement such as produced by an instrument." ;
  rdfs:subClassOf obo:ExO_0000064 .

obo:ExO_0000060 a rdfs:Class ;
  rdfs:label "injection route" ;
  rdfs:comment "An exposure route in which a subject or sample comes in contact with a stressor that has directly entered the body through punctures, bites, or needles." ;
  rdfs:subClassOf obo:ExO_0000055 .

obo:ExO_0000030 a rdfs:Class ;
  rdfs:label "ecosphere" ;
  rdfs:comment "The earth, all of the organisms living on it, and all of the environmental factors, which act on the organisms. The volume of area where biological matter can exist, slightly above, on or below ground level." ;
  rdfs:subClassOf obo:ExO_0000001 .

obo:ExO_0000112 a rdfs:Class ;
  rdfs:label "male" ;
  rdfs:comment "A person who belongs to the sex that normally produces sperm. The term is used to indicate biological sex distinctions, cultural gender role distinctions, or both." ;
  rdfs:subClassOf obo:ExO_0000110 .

obo:ExO_0000052 a rdfs:Class ;
  rdfs:label "intermittent" ;
  rdfs:comment "A quality of a single process inhering in a bearer by virtue of the bearer's being marked by breaks or interruptions." ;
  rdfs:subClassOf obo:ExO_0000051 .

obo:EXO_0000160 a rdfs:Class ;
  rdfs:label "intravenous injection route" ;
  rdfs:comment "An injection exposure route which takes place within or is administered into a vein" ;
  rdfs:subClassOf obo:ExO_0000060 .

obo:ExO_0000092 a rdfs:Class ;
  rdfs:label "environmental stressor source" ;
  rdfs:comment "The external elements and conditions which surround, influence, and affect the life and development of an organism or population." ;
  rdfs:subClassOf obo:ExO_0000016 .

obo:ExO_0000035 a rdfs:Class ;
  rdfs:label "genetic background" ;
  rdfs:comment "The individual attribute that is the genes and their composition that are characteristic of an individual or population." ;
  rdfs:subClassOf obo:ExO_0000089 .

obo:ExO_0000131 a rdfs:Class ;
  rdfs:label "workers" ;
  rdfs:comment "A person performing a job or service for another person or a business firm on a full- or part-time basis and who receives payment for this work." ;
  rdfs:subClassOf obo:ExO_0000033 .

obo:ExO_0000074 a rdfs:Class ;
  rdfs:label "mathematical" ;
  rdfs:comment "A representation of a particular system or subject matter that can be computed." ;
  rdfs:subClassOf obo:ExO_0000072 .

obo:ExO_0000085 a rdfs:Class ;
  rdfs:label "commercial product" ;
  rdfs:comment "The end result of a manufacturing process; anything that is produced." ;
  rdfs:subClassOf obo:ExO_0000016 .

obo:ExO_0000024 a rdfs:Class ;
  rdfs:label "biological process" ;
  rdfs:comment "A process occurring in living organisms." ;
  rdfs:subClassOf obo:ExO_0000023 .

obo:ExO_0000046 a rdfs:Class ;
  rdfs:label "cell" ;
  rdfs:comment "Anatomical structure that consists of a cell compartment surrounded by a plasma membrane; together with other cells and intercellular matrix, it constitutes tissues. Examples: lymphocyte, fibroblast, erythrocyte, neuron." .

obo:ExO_0000000 a rdfs:Class ;
  rdfs:label "exposure stressor" ;
  rdfs:comment "An agent, stimulus, activity, or event that causes stress or tension on an organism and interacts with an exposure_receptor during an exposure event." .

obo:ExO_0000013 a rdfs:Class ;
  rdfs:label "acid rain" ;
  rdfs:comment "An ecological perturbation that is acidic water, usually pH 2.5 to 4.5, which poisons the ecosystem and adversely affects plants, fishes, and mammals. It is caused by industrial pollutants, mainly sulfur oxides and nitrogen oxides, emitted into the atmosphere and returning to earth in the form of acidic rain water." ;
  rdfs:subClassOf obo:ExO_0000007 .

obo:ExO_0000063 a rdfs:Class ;
  rdfs:label "blood" ;
  rdfs:comment "Body substance which consists of plasma and blood cells." .

obo:ExO_0000113 a rdfs:Class ;
  rdfs:label "smoking status" ;
  rdfs:comment "An indication of a person's current tobacco and nicotine consumption as well as some indication of smoking history." ;
  rdfs:subClassOf obo:ExO_0000103 .

obo:ExO_0000071 a rdfs:Class ;
  rdfs:label "biological marker" ;
  rdfs:comment "A substance used as an indicator of a biological state." ;
  rdfs:subClassOf obo:ExO_0000064 .

obo:ExO_0000164 a rdfs:Class ;
  rdfs:label "active inhalation route" ;
  rdfs:comment "An exposure route in which a subject or sample comes in contact with a stressor by purposely breathing or inhaling the stressor or substance containing the stressor." ;
  rdfs:subClassOf obo:ExO_0000057 .

obo:ExO_0000006 a rdfs:Class ;
  rdfs:label "chemical agent" ;
  rdfs:comment "An agent of chemical origin." ;
  rdfs:subClassOf obo:ExO_0000000 .

obo:ExO_0000078 a rdfs:Class ;
  rdfs:label "molecular response" ;
  rdfs:subClassOf obo:ExO_0000077 .

obo:ExO_0000123 a rdfs:Class ;
  rdfs:label "infants or newborns" ;
  rdfs:comment "A young child between one month and two years of age or between birth and one month of age." ;
  rdfs:subClassOf obo:ExO_0000033 .

obo:ExO_0000101 a rdfs:Class ;
  rdfs:label "phenotype" ;
  rdfs:comment "The assemblage of traits or outward appearance of an individual. It is the product of interactions between genes and between genes and the environment." ;
  rdfs:subClassOf obo:ExO_0000077 .

obo:ExO_0000125 a rdfs:Class ;
  rdfs:label "mothers" ;
  rdfs:comment "A female parent." ;
  rdfs:subClassOf obo:ExO_0000033 .

obo:ExO_0000089 a rdfs:Class ;
  rdfs:label "human attribute" ;
  rdfs:comment "An attribute describing some aspect of an individual or human population." ;
  rdfs:subClassOf obo:ExO_0000033 , obo:ExO_0000042 .

obo:ExO_0000153 a rdfs:Class ;
  rdfs:label "Other Race" ;
  rdfs:comment "A person of non-specified racial, cultural, or geographic origins." ;
  rdfs:subClassOf obo:ExO_0000109 .

obo:ExO_0000097 a rdfs:Class ;
  rdfs:label "province" ;
  rdfs:comment "A region, district or division of a country; a tract; a portion a state, especially one remote from the capital." ;
  rdfs:subClassOf obo:ExO_0000096 .

obo:ExO_0000057 a rdfs:Class ;
  rdfs:label "inhalation route" ;
  rdfs:comment "An exposure route in which a subject or sample comes in contact with a stressor through breathing." ;
  rdfs:subClassOf obo:ExO_0000055 .

obo:ExO_0000082 a rdfs:Class ;
  rdfs:label "public policy" ;
  rdfs:subClassOf obo:ExO_0000003 .

obo:ExO_0000107 a rdfs:Class ;
  rdfs:label "genotype" ;
  rdfs:comment "The genetic constitution of an organism or cell, as distinct from its expressed features or phenotype." ;
  rdfs:subClassOf obo:ExO_0000103 .

obo:ExO_0000139 a rdfs:Class ;
  rdfs:label "Chinese" ;
  rdfs:comment "A person having origins in any of the original peoples of China." ;
  rdfs:subClassOf obo:ExO_0000109 .

obo:ExO_0000129 a rdfs:Class ;
  rdfs:label "subjects with gene influence" ;
  rdfs:comment "Study subjects who exhibit characteristics of a specific genotype in a research study." ;
  rdfs:subClassOf obo:ExO_0000033 .

obo:ExO_0000114 a rdfs:Class ;
  rdfs:label "socioeconomic status" ;
  rdfs:comment "Characteristics of a person such as education and occupation, used to describe the person's position in stratification systems, access to services, etc." ;
  rdfs:subClassOf obo:ExO_0000039 , obo:ExO_0000103 .

obo:ExO_0000124 a rdfs:Class ;
  rdfs:label "military personnel" ;
  rdfs:comment "Persons including soldiers involved with the armed forces." ;
  rdfs:subClassOf obo:ExO_0000033 .

<https://w3id.org/linkml/Any> a rdfs:Class ;
  rdfs:comment "An unconstrained type or object" .

obo:ExO_0000103 a rdfs:Class ;
  rdfs:label "influencing factor" ;
  rdfs:comment "Other conditions with the power to have an effect on health status." ;
  rdfs:subClassOf obo:ExO_0000038 .

obo:ExO_0000102 a rdfs:Class ;
  rdfs:label "age" ;
  rdfs:comment "How long something or someone has existed; elapsed time since birth." ;
  rdfs:subClassOf obo:ExO_0000103 .

obo:ExO_0000142 a rdfs:Class ;
  rdfs:label "Dominican" ;
  rdfs:comment "Denotes the inhabitants of the Dominican Republic, a person from there, or their descendants elsewhere." ;
  rdfs:subClassOf obo:ExO_0000109 .

obo:ExO_0000016 a rdfs:Class ;
  rdfs:label "source" ;
  rdfs:comment "Where something is available or from where it originates." .

obo:ExO_0000118 a rdfs:Class ;
  rdfs:label "non-smoker" ;
  rdfs:comment "A person who was not smoking at the time of the interview and has smoked less than 100 cigarettes in their life." ;
  rdfs:subClassOf obo:ExO_0000113 .

obo:ExO_0000041 a rdfs:Class ;
  rdfs:label "education" ;
  rdfs:comment "The act or process of imparting or acquiring knowledge." ;
  rdfs:subClassOf obo:ExO_0000039 .

obo:ExO_0000079 a rdfs:Class ;
  rdfs:label "disease" ;
  rdfs:comment "A disease is a pattern of abnormal functioning, or abnormal localization of normal functioning, and/or abnormal localization of constituents when compared to other members of that species." ;
  rdfs:subClassOf obo:ExO_0000077 , obo:ExO_0000103 .

obo:ExO_0000001 a rdfs:Class ;
  rdfs:label "exposure recipient" ;
  rdfs:comment "An entity (e.g., a human, human population, or a human organ) that interacts with an exposure stimulus during an exposure event." .

obo:IAO_0000115 a rdf:Property ;
  rdfs:label "definition" ;
  rdfs:range xsd:string .