PREFIX obo: <http://purl.obolibrary.org/obo/>
PREFIX rdf: <http://www.w3.org/1999/02/22-rdf-syntax-ns#>
PREFIX rdfs: <http://www.w3.org/2000/01/rdf-schema#>
PREFIX xsd: <http://www.w3.org/2001/XMLSchema#>

obo:SYMP_0000435 a rdfs:Class ;
  rdfs:label "paresthesia" ;
  rdfs:comment "Paresthesia is a skin and integumentary tissue symptom characterized as a sensation of pricking, tingling, or creeping on the skin having no objective cause and usually associated with injury or irritation of a sensory nerve or nerve root." ;
  rdfs:subClassOf obo:SYMP_0000488 .

<https://bio.scai.fraunhofer.de/ontology/0000405> a rdf:Property ;
  rdfs:label "isSignAndSymptomFor" ;
  rdfs:range <https://w3id.org/linkml/Any> .

obo:DOID_13027 a rdfs:Class ;
  rdfs:label "transient global amnesia" ;
  rdfs:comment "An amnestic disorder that is characterized by temporary but almost total disruption of short-term memory with a range of problems accessing older memories." ;
  rdfs:subClassOf obo:DOID_10914 .

obo:OGMS_0000037 a rdfs:Class ;
  rdfs:label "abnormal homeostasis" ;
  rdfs:comment "Homeostasis that is clinically abnormal for an organism of a given type and age in a given environment." ;
  rdfs:subClassOf obo:OGMS_0000032 .

<https://bio.scai.fraunhofer.de/ontology/0000500> a rdfs:Class ;
  rdfs:label "connectivity" ;
  rdfs:subClassOf obo:BFO_0000031 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#epilepsy_imitator> a rdfs:Class ;
  rdfs:label "epilepsy imitator" ;
  rdfs:seeAlso <https://stanfordhealthcare.org/medical-conditions/brain-and-nerves/epilepsy/symptoms/imitators.html> ;
  rdfs:subClassOf <https://bio.scai.fraunhofer.de/ontology/epilepsy#International_League_Against_Epilepsy_classification> .

<https://bio.scai.fraunhofer.de/ontology/0000410> a rdf:Property ;
  rdfs:label "isImitatorFor" ;
  rdfs:range <https://w3id.org/linkml/Any> .

obo:UBERON_0013535 a rdfs:Class ;
  rdfs:label "Brodmann (1909) area 4" ;
  rdfs:comment "The term area 4 of Brodmann-1909 refers to a cytoarchitecturally defined portion of the frontal lobe of the guenon. It is located predominantly in the precentral gyrus. Brodmann-1909 regarded it as topographically and cytoarchitecturally homologous to the human gigantopyramidal area 4 and noted that it occupies a much greater fraction of the frontal lobe in the monkey than in the human. Distinctive features (Brodmann-1905): the cortex is unusually thick; the layers are not distinct; the cells are relatively sparsely distributed; giant pyramidal (Betz) cells are present in the internal pyramidal layer (V); lack of an internal granular layer (IV) such that the boundary between the external pyramidal layer (III) and the internal pyramidal layer (V) is indistinct; lack of a distinct external granular layer (II); a gradual transition from the multiform layer (VI) to the subcortical white matter." ;
  rdfs:seeAlso <https://github.com/obophenotype/uberon/issues/515> ;
  rdfs:subClassOf obo:UBERON_0013529 .

<https://bio.scai.fraunhofer.de/ontology/0000418> a rdf:Property ;
  rdfs:label "isAnatomicalEntityFor" ;
  rdfs:range <https://w3id.org/linkml/Any> .

obo:HP_0011004 a rdfs:Class ;
  rdfs:label "Abnormal systemic arterial morphology" ;
  rdfs:comment "An abnormality of the systemic arterial tree, which consists of the aorta and other systemic arteries." ;
  rdfs:subClassOf obo:HP_0025015 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#N-methyl-DL-aspartate_model> a rdfs:Class ;
  rdfs:label "N-methyl-DL-aspartate model" ;
  rdfs:subClassOf <https://bio.scai.fraunhofer.de/ontology/epilepsy#convulsant_drug_model> .

obo:HP_0000708 a rdfs:Class ;
  rdfs:label "Behavioral abnormality" ;
  rdfs:comment "An abnormality of mental functioning including various affective, behavioural, cognitive and perceptual abnormalities." ;
  rdfs:subClassOf obo:HP_0012638 .

obo:HP_0000712 a rdfs:Class ;
  rdfs:label "Emotional lability" ;
  rdfs:comment "Unstable emotional experiences and frequent mood changes; emotions that are easily aroused, intense, and/or out of proportion to events and circumstances." ;
  rdfs:subClassOf obo:HP_0031466 .

obo:SYMP_0000075 a rdfs:Class ;
  rdfs:label "lethargy" ;
  rdfs:comment "Lethargy is a fatigue characterized as abnormal drowsiness." ;
  rdfs:seeAlso <https://www.epilepsy.org.uk/info/wellbeing/fatigue> ;
  rdfs:subClassOf obo:SYMP_0019177 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#focal_motor_seizure_with_dysarthria_/_anarthria> a rdfs:Class ;
  rdfs:label "focal motor seizure with dysarthria / anarthria" ;
  rdfs:subClassOf obo:HP_0011153 .

<https://bio.scai.fraunhofer.de/ontology/0000414> a rdf:Property ;
  rdfs:label "isSeizureClassificationFor" ;
  rdfs:range <https://w3id.org/linkml/Any> .

obo:UBERON_0002336 a rdfs:Class ;
  rdfs:label "corpus callosum" ;
  rdfs:comment "White matter structure containing massive numbers of commissural fibers connecting cortical areas in the two cerebral hemispheres.it is subdivided into a genu, a rostrum, a body, and a splenium. (MM)" ;
  rdfs:seeAlso <https://www.webmd.com/epilepsy/guide/corpus-callosotomy#1> , <https://www.epilepsy.com/learn/professionals/diagnosis-treatment/surgery/corpus-callosotomy> ;
  rdfs:subClassOf obo:UBERON_0002473 , obo:UBERON_0005340 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#sialorrheic_seizure> a rdfs:Class ;
  rdfs:label "sialorrheic seizure" ;
  rdfs:seeAlso <http://www.case.edu/EpSO.owl#SialorrheicSeizure> ;
  rdfs:subClassOf obo:SYMP_0000124 .

obo:HP_0011158 a rdfs:Class ;
  rdfs:label "Focal sensory auditory seizure" ;
  rdfs:comment "A type of focal sensory seizure that is characterized by elementary auditory phenomena including buzzing, ringing, drumming or single tones." ;
  rdfs:seeAlso <http://www.case.edu/EpSO.owl#ElementaryAuditoryAura> , <http://www.case.edu/EpSO.owl#AuditoryAura> , <http://www.case.edu/EpSO.owl#ComplexAuditoryAura> ;
  rdfs:subClassOf obo:HP_0011157 .

obo:MONDO_0015654 a rdfs:Class ;
  rdfs:label "idiopathic or cryptogenic familial epilepsy syndrome with identified loci/genes" ;
  rdfs:subClassOf obo:DOID_1826 .

<https://bio.scai.fraunhofer.de/ontology/ac113c60_c3d8_48f2_871c_cc34524d844f> a rdf:Property ;
  rdfs:label "isClassificationFor" ;
  rdfs:range <https://w3id.org/linkml/Any> .

obo:NCIT_C35470 a rdfs:Class ;
  rdfs:label "Behavioral Disorder" ;
  rdfs:comment "A specific behavioral problem that occurs in persistent patterns and characteristic clusters and that causes clinically significant impairment." ;
  rdfs:seeAlso <https://www.epilepsydiagnosis.org/epilepsy-imitators.html#behavioral> ;
  rdfs:subClassOf <https://bio.scai.fraunhofer.de/ontology/epilepsy#epilepsy_imitator> .

obo:DOID_8986 a rdfs:Class ;
  rdfs:label "narcolepsy" ;
  rdfs:comment "A sleep disorder that involves an excessive urge to sleep at inappropriate times, such as while at work." ;
  rdfs:seeAlso <https://www.epilepsy.com/learn/professionals/co-existing-disorders/sleep-disorders/narcolepsy> , <http://www.case.edu/EpSO.owl#Narcolepsy> ;
  rdfs:subClassOf obo:NBO_0000419 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#rotational_vertical> a rdfs:Class ;
  rdfs:label "rotational vertical" ;
  rdfs:seeAlso <https://www.aafp.org/afp/2006/0115/p244.html> ;
  rdfs:subClassOf obo:SYMP_0000399 .

obo:DOID_0060326 a rdfs:Class ;
  rdfs:label "myelomeningocele" ;
  rdfs:comment "A spina bifida characterized by protrusion of the spinal cord through an opening, covered by meningeal membranes." ;
  rdfs:subClassOf obo:DOID_0080016 , obo:DOID_319 .

obo:DOID_0060037 a rdfs:Class ;
  rdfs:label "developmental disorder of mental health" ;
  rdfs:comment "A disease of mental health that occur during a child's developmental period between birth and age 18 resulting in retarding of the child's psychological or physical development." ;
  rdfs:subClassOf obo:DOID_150 .

obo:HP_0001939 a rdfs:Class ;
  rdfs:label "Abnormality of metabolism/homeostasis" ;
  rdfs:subClassOf obo:HP_0000118 .

obo:DOID_934 a rdfs:Class ;
  rdfs:label "viral infectious disease" ;
  rdfs:comment "A disease by infectious agent that results in infection, has_material_basis_in Viruses." ;
  rdfs:subClassOf obo:DOID_0050117 .

<https://bio.scai.fraunhofer.de/ontology/0000401> a rdf:Property ;
  rdfs:label "isRiskFactorFor" ;
  rdfs:range <https://w3id.org/linkml/Any> .

obo:DOID_680 a rdfs:Class ;
  rdfs:label "tauopathy" ;
  rdfs:comment "A neurodegenerative disease that has_material_basis_in the pathological aggregation of tau protein in so-called neurofibrillary tangles (NFT) in the human brain." ;
  rdfs:subClassOf obo:DOID_1289 .

obo:OBI_0000094 a rdfs:Class ;
  rdfs:label "material processing" ;
  rdfs:comment "A planned process which results in physical changes in a specified input material" ;
  rdfs:subClassOf obo:ERO_0000007 .

obo:MP_0005604 a rdfs:Class ;
  rdfs:label "hyperekplexia" ;
  rdfs:comment "disorder characterized by pathologic startle responses, protective reactions to unanticipated, potentially threatening, stimuli of any type, particularly auditory" ;
  rdfs:seeAlso <https://rarediseases.org/rare-diseases/hyperekplexia/> ;
  rdfs:subClassOf obo:MONDO_0017657 .

obo:DOID_0050177 a rdfs:Class ;
  rdfs:label "monogenic disease" ;
  rdfs:comment "A genetic disease that is the result of one or more abnormal alleles and may be dominant, semi-dominant, or recessive." ;
  rdfs:subClassOf obo:DOID_630 .

obo:DOID_0080422 a rdfs:Class ;
  rdfs:label "Dravet syndrome" ;
  rdfs:comment "An early infantile epileptic encephalopathy that has_material_basis_in heterozygous mutation in the SCN1A gene on chromosome 2q24." ;
  rdfs:subClassOf obo:MONDO_0100022 .

<https://bio.scai.fraunhofer.de/ontology/0000409> a rdf:Property ;
  rdfs:label "isSyndromeFor" ;
  rdfs:range <https://w3id.org/linkml/Any> .

obo:MP_0004085 a rdfs:Class ;
  rdfs:label "abnormal heartbeat" ;
  rdfs:comment "anomaly in the appearance of regularly spaced contractions of the heart due to defects in the frequency, rate, pattern or extent of heart contraction" ;
  rdfs:subClassOf obo:HP_0001626 .

obo:HP_0011097 a rdfs:Class ;
  rdfs:label "Epileptic spasms" ;
  rdfs:comment "A sudden flexion, extension or mixed extension-flexion of predominantly proximal and truncal muscles which is usually more sustained than a myoclonic movement but not as sustained as a tonic seizure." ;
  rdfs:seeAlso <https://www.epilepsydiagnosis.org/seizure/motor-overview.html> ;
  rdfs:subClassOf obo:HP_0011153 , <https://bio.scai.fraunhofer.de/ontology/epilepsy#generalized_motor_onset_seizure> .

obo:HP_0011842 a rdfs:Class ;
  rdfs:label "Abnormality of skeletal morphology" ;
  rdfs:comment "An abnormality of the form, structure, or size of the skeletal system." ;
  rdfs:subClassOf obo:HP_0000924 .

obo:HP_0002597 a rdfs:Class ;
  rdfs:label "Abnormality of the vasculature" ;
  rdfs:comment "An abnormality of the vasculature." ;
  rdfs:subClassOf obo:HP_0001626 .

obo:OMIT_0027689 a rdfs:Class ;
  rdfs:label "Functional Neuroimaging" ;
  rdfs:subClassOf obo:OMIT_0027688 .

<https://bio.scai.fraunhofer.de/ontology/cac13978_e4e8_4240_907f_80ddfd3af981> a rdf:Property ;
  rdfs:label "isBrainConnectivityFor" ;
  rdfs:range <https://w3id.org/linkml/Any> .

obo:UBERON_0034768 a rdfs:Class ;
  rdfs:label "morphological feature" ;
  rdfs:comment "A part of an organism or organ that is continuous with its surroundings and distinguished from its surroundings based on morphology." ;
  rdfs:subClassOf obo:UBERON_0000061 .

obo:BFO_0000034 a rdfs:Class ;
  rdfs:label "function" ;
  rdfs:subClassOf obo:BFO_0000016 .

<https://bio.scai.fraunhofer.de/ontology/0000512> a rdfs:Class ;
  rdfs:label "stereotactic electroencephalogaphy" ;
  rdfs:subClassOf obo:OBI_0002186 .

<https://bio.scai.fraunhofer.de/ontology/0000403> a rdf:Property ;
  rdfs:label "isDiagnosisFor" ;
  rdfs:range <https://w3id.org/linkml/Any> .

obo:MMO_0000147 a rdfs:Class ;
  rdfs:label "urine analysis" ;
  rdfs:comment "Any method to determine the nature, properties, or composition of urine, the fluid waste product excreted by the kidneys, including measurement of the volume of urine or of the quantity or quality of component parts of urine." ;
  rdfs:subClassOf obo:CMO_0000000 .

obo:HP_0001123 a rdfs:Class ;
  rdfs:label "Visual field defect" ;
  rdfs:subClassOf obo:HP_0000505 .

obo:MONDO_0016158 a rdfs:Class ;
  rdfs:label "narcolepsy-cataplexy syndrome" ;
  rdfs:comment "Narcolepsy with cataplexy is a sleep disorder characterized by excessive day-time sleepiness associated with uncontrollable sleep urges and cataplexy (loss of muscle tone often triggered by pleasant emotions)." ;
  rdfs:subClassOf obo:DOID_535 .

obo:BFO_0000017 a rdfs:Class ;
  rdfs:label "realizable entity" ;
  rdfs:subClassOf obo:BFO_0000020 .

obo:DOID_1059 a rdfs:Class ;
  rdfs:label "intellectual disability" ;
  rdfs:comment "A specific developmental disorder that involves significant limitations both in mental functioning and in adaptive behavior such as communicating, taking care of him or herself, and social skills." ;
  rdfs:seeAlso <https://www.psychiatryadvisor.com/home/topics/neurodevelopmental-disorder/intellectual-disabilities/managing-epilepsy-in-patients-with-intellectual-disability/> , <http://www.case.edu/EpSO.owl#MentalRetardation> ;
  rdfs:subClassOf obo:DOID_0060038 .

obo:HP_0011153 a rdfs:Class ;
  rdfs:label "Focal motor seizure" ;
  rdfs:comment "A type of focal-onset seizure characterized by a motor sign as its initial semiological manifestation." ;
  rdfs:seeAlso <https://www.medicinenet.com/script/main/art.asp?articlekey=32972> ;
  rdfs:subClassOf <https://bio.scai.fraunhofer.de/ontology/epilepsy#focal_seizure_classification_by_onset_feature> .

obo:UBERON_0000465 a rdfs:Class ;
  rdfs:label "material anatomical entity" ;
  rdfs:comment "Anatomical entity that has mass." ;
  rdfs:subClassOf obo:UBERON_0001062 .

obo:NCIT_C101035 a rdfs:Class ;
  rdfs:label "Neonatal Injury Related to Birth" ;
  rdfs:comment "An injury sustained to a neonate during the birthing process." ;
  rdfs:seeAlso <http://www.case.edu/EpSO.owl#BirthInjury> ;
  rdfs:subClassOf obo:OGMS_0000102 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#mu_rhythm> a rdfs:Class ;
  rdfs:label "mu rhythm" ;
  rdfs:seeAlso <http://www.case.edu/EpSO.owl#MuRhythm> , <https://emedicine.medscape.com/article/1139332-overview#a1> ;
  rdfs:subClassOf <https://bio.scai.fraunhofer.de/ontology/epilepsy#normal_EEG_pattern> .

obo:DOID_0060394 a rdfs:Class ;
  rdfs:label "chromosome 15q13.3 microdeletion syndrome" ;
  rdfs:comment "A chromosomal deletion syndrome that is characterized by intellectual dsability, developmental delay, autism spectrum disorder and seizure, has_material_basis_in autosomal dominant inheritance of partial deletion of the long arm of chromosome 15." ;
  rdfs:subClassOf obo:MONDO_0019040 .

<https://bio.scai.fraunhofer.de/ontology/0000412> a rdf:Property ;
  rdfs:label "isEtiologyFor" ;
  rdfs:range <https://w3id.org/linkml/Any> .

obo:UBERON_0002769 a rdfs:Class ;
  rdfs:label "superior temporal gyrus" ;
  rdfs:comment "Component of the temporal lobe, lateral aspect. The rostral boundary is the rostral extent of the ssuperior temporal sulcus. The caudal boundary is the cauday portion of the superior temporal gyrus (posterior to becoming continuous with the supramarginal gyrus). The medial boundary is the lateral fissure (and when present the supramarginal gyrus), and the lateral boundary is the superior temporal suclus (Christine Fennema-Notestine)." ;
  rdfs:subClassOf obo:UBERON_0000200 .

obo:HP_0010931 a rdfs:Class ;
  rdfs:label "Abnormal blood sodium concentration" ;
  rdfs:comment "An abnormal concentration of sodium." ;
  rdfs:subClassOf obo:HP_0010930 .

obo:DOID_2030 a rdfs:Class ;
  rdfs:label "anxiety disorder" ;
  rdfs:comment "A cognitive disorder that involves an excessive, irrational dread of everyday situations." ;
  rdfs:subClassOf obo:DOID_1561 .

obo:HP_0000805 a rdfs:Class ;
  rdfs:label "Enuresis" ;
  rdfs:comment "Lack of the ability to control the urinary bladder leading to involuntary urination at an age where control of the bladder should already be possible." ;
  rdfs:subClassOf obo:HP_0000009 .

obo:HP_0008373 a rdfs:Class ;
  rdfs:label "Puberty and gonadal disorders" ;
  rdfs:subClassOf obo:HP_0000818 .

obo:UBERON_0002616 a rdfs:Class ;
  rdfs:label "regional part of brain" ;
  rdfs:comment "Anatomical divisons of the brain according to one or more criteria, e.g. cytoarchitectural, gross anatomy. Parts may be contiguous in 3D or not, e.g., basal ganglia." ;
  rdfs:subClassOf obo:UBERON_0000073 .

obo:MONDO_0018027 a rdfs:Class ;
  rdfs:label "duplication/inversion 15q11" ;
  rdfs:comment "Isodicentric chromosome 15 syndrome is a chromosome abnormality that affects many different parts of the body. As the name suggests, people with this condition have an extra chromosome (called an isodicentric chromosome 15 ) which is made of two pieces of chromosome 15 that are stuck together end-to-end. Although the severity of the condition and the associated features vary from person to person, common signs and symptoms include poor muscle tone in newborns; developmental delay; mild to severe intellectual disability; delayed or absent speech; behavioral abnormalities; and seizures . Most cases of isodicentric chromosome 15 syndrome occur sporadically in people with no family history of the condition. Treatment is based on the signs and symptoms present in each person." ;
  rdfs:subClassOf obo:MONDO_0019040 .

obo:UBERON_0007702 a rdfs:Class ;
  rdfs:label "tract of brain" ;
  rdfs:comment "An axon tract that is part of a brain." ;
  rdfs:subClassOf obo:UBERON_0001018 .

obo:DOID_1205 a rdfs:Class ;
  rdfs:label "allergic hypersensitivity disease" ;
  rdfs:comment "An immune system disease that is an exaggerated immune response to allergens, such as insect venom, dust mites, pollen, pet dander, drugs or some foods." ;
  rdfs:subClassOf obo:DOID_0060056 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#horizontal_occular_oscillation> a rdfs:Class ;
  rdfs:label "horizontal occular oscillation" ;
  rdfs:seeAlso <https://iovs.arvojournals.org/article.aspx?articleid=2165843> ;
  rdfs:subClassOf <https://bio.scai.fraunhofer.de/ontology/epilepsy#occular_oscillation> .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#electrographic_seizure> a rdfs:Class ;
  rdfs:label "electrographic seizure" ;
  rdfs:subClassOf obo:SYMP_0000124 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#lateral_parietal_epilepsy> a rdfs:Class ;
  rdfs:label "lateral parietal epilepsy" ;
  rdfs:seeAlso <http://www.case.edu/EpSO.owl#LateralParietalEpilepsy> ;
  rdfs:subClassOf <https://bio.scai.fraunhofer.de/ontology/epilepsy#parietal_lobe_epilepsy> .

obo:SYMP_0019184 a rdfs:Class ;
  rdfs:label "limited attention" ;
  rdfs:comment "A behavioral symptom that is characterized by a restricted rate of information processing by the brain." ;
  rdfs:seeAlso <https://www.epilepsy.com/learn/challenges-epilepsy/moods-and-behavior/mood-and-behavior-advanced/impaired-attention> ;
  rdfs:subClassOf obo:SYMP_0019182 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#late_post-traumatic_seizure> a rdfs:Class ;
  rdfs:label "late post-traumatic seizure" ;
  rdfs:subClassOf obo:SYMP_0000124 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#mesial_parietal_epilepsy> a rdfs:Class ;
  rdfs:label "mesial parietal epilepsy" ;
  rdfs:seeAlso <http://www.case.edu/EpSO.owl#MesialParietalEpilepsy> ;
  rdfs:subClassOf <https://bio.scai.fraunhofer.de/ontology/epilepsy#parietal_lobe_epilepsy> .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#calcium-activated_potassium_channel_model> a rdfs:Class ;
  rdfs:label "calcium-activated potassium channel model" ;
  rdfs:subClassOf obo:NCIT_C19146 .

obo:DOID_0050453 a rdfs:Class ;
  rdfs:label "lissencephaly" ;
  rdfs:comment "A congenital nervous system abnormality characterized by the absence of folds in the cerebral cortex and caused_by defective neuronal migration during the 12th to 24th weeks of gestation." ;
  rdfs:subClassOf obo:NCIT_C84834 .

obo:DOID_2426 a rdfs:Class ;
  rdfs:label "gangliocytoma" ;
  rdfs:comment "A central nervous system benign neoplasm that has_material_basis_in mature neurons, and is classified by the absence of neoplastic glial cells." ;
  rdfs:seeAlso <http://www.case.edu/EpSO.owl#Gangliocytoma> ;
  rdfs:subClassOf obo:DOID_0060090 .

obo:SYMP_0000459 a rdfs:Class ;
  rdfs:label "digestive system symptom" ;
  rdfs:subClassOf obo:SYMP_0000462 .

obo:OMIT_0007783 a rdfs:Class ;
  rdfs:label "Hippocampus" ;
  rdfs:seeAlso <http://www.case.edu/EpSO.owl#Hippocampus> ;
  rdfs:subClassOf obo:UBERON_0000956 .

obo:MONDO_0005287 a rdfs:Class ;
  rdfs:label "developmental disability" ;
  rdfs:comment "Disorders in which there is a delay in development based on that expected for a given age level or stage of development. These impairments or disabilities originate before age 18, may be expected to continue indefinitely, and constitute a substantial impairment. Biological and nonbiological factors are involved in these disorders. (From American Psychiatric Glossary, 6th ed)" ;
  rdfs:subClassOf obo:DOID_0060037 .

obo:CMO_0000182 a rdfs:Class ;
  rdfs:label "head morphological measurement" ;
  rdfs:subClassOf obo:CMO_0000021 .

obo:NCIT_C118304 a rdfs:Class ;
  rdfs:label "Micropsia" ;
  rdfs:comment "An alteration in visual perception that causes objects to appear smaller than their actual size." ;
  rdfs:subClassOf obo:HP_0000504 .

obo:DOID_10652 a rdfs:Class ;
  rdfs:label "Alzheimer's disease" ;
  rdfs:comment "A tauopathy that is characterized by memory lapses, confusion, emotional instability and progressive loss of mental ability and results in progressive memory loss, impaired thinking, disorientation, and changes in personality and mood starting and leads in advanced cases to a profound decline in cognitive and physical functioning and is marked histologically by the degeneration of brain neurons especially in the cerebral cortex and by the presence of neurofibrillary tangles and plaques containing beta-amyloid." ;
  rdfs:subClassOf obo:DOID_680 .

obo:ERO_0001764 a rdfs:Class ;
  rdfs:label "polysomnography" ;
  rdfs:comment "A physiological assay used in the study of sleep and as a diagnostic tool in sleep medicine. " ;
  rdfs:subClassOf obo:ERO_0001292 .

obo:NCIT_C161601 a rdfs:Class ;
  rdfs:label "Surgical Procedure by Type" ;
  rdfs:comment "A categorization of surgical procedures by type or purpose." ;
  rdfs:subClassOf obo:OMIABIS_0001041 .

obo:NCIT_C162646 a rdfs:Class ;
  rdfs:label "7 Tesla Magnetic Resonance Imaging" ;
  rdfs:comment "MRI that uses a magnet capable of producing a 7 telsa field strength. This increased magnet strength is can produce images with greater signal-to-noise ratio and increased spatial resolution, or faster imaging at standard resolution." ;
  rdfs:subClassOf obo:ERO_0001235 .

obo:HP_0002069 a rdfs:Class ;
  rdfs:label "Generalized tonic-clonic seizures" ;
  rdfs:comment "Generalized tonic-clonic seizures are generalized seizures with bilateral symmetrical tonic contraction then bilateral clonic contractions of somatic muscles usually associated with autonomic phenomena." ;
  rdfs:subClassOf <https://bio.scai.fraunhofer.de/ontology/epilepsy#generalized_motor_onset_seizure> .

obo:MONDO_0016019 a rdfs:Class ;
  rdfs:label "Rasmussen subacute encephalitis" ;
  rdfs:comment "A rare, progressive chronic inflammation of a single cerebral hemisphere that usually affects children. It is characterized by severe seizures, loss of motor skills and speech, hemiparesis, and dementia." ;
  rdfs:seeAlso <http://www.case.edu/EpSO.owl#RasmussenEncephalitis> ;
  rdfs:subClassOf <https://bio.scai.fraunhofer.de/ontology/epilepsy#immune_etiology> .

obo:MONDO_0016702 a rdfs:Class ;
  rdfs:label "oligoastrocytoma" ;
  rdfs:comment "A WHO grade II tumor composed of a conspicuous mixture of two distinct neoplastic cell types morphologically resembling the tumor cells in oligodendroglioma and diffuse astrocytoma. (WHO)" ;
  rdfs:seeAlso <http://www.case.edu/EpSO.owl#Oligoastrocytoma> ;
  rdfs:subClassOf obo:MONDO_0016701 , obo:MONDO_0021639 .

obo:EUPATH_0011795 a rdfs:Class ;
  rdfs:label "blood test" ;
  rdfs:comment "a laboratory test that has a blood specimen as specified input" ;
  rdfs:seeAlso <https://www.webmd.com/epilepsy/guide/epilepsy-blood-test> ;
  rdfs:subClassOf obo:OBI_0000070 .

obo:BFO_0000145 a rdfs:Class ;
  rdfs:label "relational quality" ;
  rdfs:comment "b is a relational quality = Def. for some independent continuants c, d and for some time t: b quality_of c at t & b quality_of d at t. (axiom label in BFO2 Reference: [057-001])" ;
  rdfs:subClassOf obo:BFO_0000019 .

obo:MP_0004874 a rdfs:Class ;
  rdfs:label "abnormal timing of postnatal eyelid opening" ;
  rdfs:comment "anomaly in the average time for the first postnatal eye opening, or failure of eyes to ever open" ;
  rdfs:subClassOf obo:MP_0001340 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#seizure_associated_with_human_immunodeficiency_virus_infection> a rdfs:Class ;
  rdfs:label "seizure associated with human immunodeficiency virus infection" ;
  rdfs:subClassOf <https://bio.scai.fraunhofer.de/ontology/epilepsy#infectious_cause_of_seizure> .

obo:SYMP_0000488 a rdfs:Class ;
  rdfs:label "skin and integumentary tissue symptom" ;
  rdfs:subClassOf obo:SYMP_0000462 .

obo:HP_0020207 a rdfs:Class ;
  rdfs:label "Reflex seizure" ;
  rdfs:comment "Seizures precipitated by exogenous stimuli." ;
  rdfs:subClassOf obo:SYMP_0000124 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#responsive_neurostimulation> a rdfs:Class ;
  rdfs:label "responsive neurostimulation" ;
  rdfs:subClassOf obo:OGMS_0000112 .

<https://bio.scai.fraunhofer.de/ontology/0000416> a rdf:Property ;
  rdfs:label "isTreatmentFor" ;
  rdfs:range <https://w3id.org/linkml/Any> .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#occular_oscillation> a rdfs:Class ;
  rdfs:label "occular oscillation" ;
  rdfs:subClassOf obo:HP_0000496 .

obo:DOID_9428 a rdfs:Class ;
  rdfs:label "intracranial hypertension" ;
  rdfs:comment "A brain disease that is characterized by high pressure inside the skull, the brain tissue and cerebrospinal fluid, has_symptom headache, has_symptom vomiting, has_symptom altered mental status, has_symptom papilledema." ;
  rdfs:subClassOf obo:NCIT_C69023 .

obo:DOID_37 a rdfs:Class ;
  rdfs:label "skin disease" ;
  rdfs:comment "An integumentary system disease that is located_in skin." ;
  rdfs:subClassOf obo:DOID_16 .

obo:SYMP_0000528 a rdfs:Class ;
  rdfs:label "cardiovascular system symptom" ;
  rdfs:subClassOf obo:SYMP_0000462 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#paroxysmal_nonkinesigenic_dyskinesia> a rdfs:Class ;
  rdfs:label "paroxysmal nonkinesigenic dyskinesia" ;
  rdfs:subClassOf obo:MONDO_0017657 .

obo:OAE_0002430 a rdfs:Class ;
  rdfs:label "acupuncture" ;
  rdfs:comment "Acupuncture is the stimulation of specific acupuncture points along the skin of the body using thin needles. It can be associated with the application of heat, pressure, or laser light to these same points." ;
  rdfs:subClassOf obo:OAE_0000002 .

obo:HP_0011029 a rdfs:Class ;
  rdfs:label "Internal hemorrhage" ;
  rdfs:comment "The presence of hemorrhage within the body." ;
  rdfs:subClassOf obo:HP_0001892 , obo:HP_0011028 .

<http://www.ebi.ac.uk/efo/EFO_0005210> a rdfs:Class ;
  rdfs:label "brain connectivity measurement" ;
  rdfs:comment "quantification of the pattern of links between distinct units within a nervous system through neuroimaging techniques such a MRI" ;
  rdfs:subClassOf <http://www.ebi.ac.uk/efo/EFO_0004346> .

obo:MONDO_0003155 a rdfs:Class ;
  rdfs:label "cavernous hemangioma" ;
  rdfs:comment "A hemangioma characterized by the presence of cavernous vascular spaces." ;
  rdfs:seeAlso <http://www.case.edu/EpSO.owl#CavernousAngioma> ;
  rdfs:subClassOf obo:DOID_1287 .

obo:HP_0002795 a rdfs:Class ;
  rdfs:label "Functional respiratory abnormality" ;
  rdfs:comment "This category describes not-primarily structural lesions." ;
  rdfs:subClassOf obo:HP_0002086 .

obo:NCBITaxon_6239 a rdfs:Class ;
  rdfs:label "Caenorhabditis elegans" ;
  rdfs:subClassOf obo:NCBITaxon_6231 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#low_magnesium_slice_model> a rdfs:Class ;
  rdfs:label "low magnesium slice model" ;
  rdfs:subClassOf obo:NCIT_C19146 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#focal_non_convulsive_status_epilepticus> a rdfs:Class ;
  rdfs:label "focal non convulsive status epilepticus" ;
  rdfs:subClassOf obo:HP_0032671 .

obo:DOID_2377 a rdfs:Class ;
  rdfs:label "multiple sclerosis" ;
  rdfs:comment "A demyelinating disease that involves damage to the fatty myelin sheaths around the axons of the brain and spinal cord resulting in demyelination and scarring." ;
  rdfs:subClassOf obo:DOID_0060004 , obo:DOID_3213 .

obo:SYMP_0000511 a rdfs:Class ;
  rdfs:label "flushing" ;
  rdfs:comment "Flushing is a skin and integumentary tissue symptom characterized as a markedly red flush in a persons face and often other areas of the skin, from various physiological conditions. Flushing is generally distinguished, despite a close physiological relation between them, from blushing, which is milder, generally restricted to the face or cheeks, and generally assumed to reflect embarrassment. Flushing is also a cardinal symptom of carcinoid syndrome the syndrome that results from hormones (often serotonin or histamine) being secreted into systemic circulation." ;
  rdfs:subClassOf obo:SYMP_0000488 .

obo:HP_0000271 a rdfs:Class ;
  rdfs:label "Abnormality of the face" ;
  rdfs:comment "An abnormality of the face." ;
  rdfs:subClassOf obo:HP_0000234 .

obo:HP_0030972 a rdfs:Class ;
  rdfs:label "Abnormal systemic blood pressure" ;
  rdfs:comment "A chronic deviation from normal pressure in the systemic arterial system." ;
  rdfs:subClassOf obo:HP_0011025 .

obo:UBERON_0005358 a rdfs:Class ;
  rdfs:label "ventricle of nervous system" ;
  rdfs:comment "A layer in the central nervous system that lines system of communicating cavities in the brain and spinal cord." ;
  rdfs:subClassOf obo:UBERON_0004923 .

obo:SYMP_0000567 a rdfs:Class ;
  rdfs:label "general symptom" ;
  rdfs:subClassOf obo:SYMP_0000462 .

obo:NCBITaxon_9544 a rdfs:Class ;
  rdfs:label "Macaca mulatta" ;
  rdfs:subClassOf obo:NCBITaxon_9443 .

obo:DOID_0050739 a rdfs:Class ;
  rdfs:label "autosomal genetic disease" ;
  rdfs:comment "A monogenic disease that has_material_basis_in a mutation in a single gene on one of the non-sex chromosomes." ;
  rdfs:subClassOf obo:DOID_0050177 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#autoimmune_epilepsy> a rdfs:Class ;
  rdfs:label "autoimmune epilepsy" ;
  rdfs:subClassOf obo:DOID_4 .

obo:NCBITaxon_131567 a rdfs:Class ;
  rdfs:label "cellular organisms" ;
  rdfs:subClassOf obo:NCBITaxon_1 .

obo:NCIT_C9487 a rdfs:Class ;
  rdfs:label "Intractable Epilepsy" ;
  rdfs:comment "Epilepsy that is refractory to treatment." ;
  rdfs:subClassOf obo:DOID_1826 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#jitteriness> a rdfs:Class ;
  rdfs:label "jitteriness" ;
  rdfs:subClassOf obo:NCIT_C69023 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#symptomatic_epilepsy> a rdfs:Class ;
  rdfs:label "symptomatic epilepsy" ;
  rdfs:subClassOf obo:DOID_1826 .

obo:DOID_9207 a rdfs:Class ;
  rdfs:label "periodic limb movement disorder" ;
  rdfs:comment "A sleep disorder that involves involuntary limb movement during sleep." ;
  rdfs:seeAlso <http://www.case.edu/EpSO.owl#PeriodicLimbMovementDisorder> , <https://www.epilepsy.com/learn/professionals/co-existing-disorders/sleep-disorders/periodic-limb-movements-and-restless-legs> ;
  rdfs:subClassOf obo:DOID_535 .

obo:OMIT_0011757 a rdfs:Class ;
  rdfs:label "Photic Stimulation" ;
  rdfs:subClassOf obo:ERO_0000007 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#mesial_occipital_epilepsy> a rdfs:Class ;
  rdfs:label "mesial occipital epilepsy" ;
  rdfs:seeAlso <http://www.case.edu/EpSO.owl#MesialOccipitalEpilepsy> ;
  rdfs:subClassOf <https://bio.scai.fraunhofer.de/ontology/epilepsy#occipital_lobe_epilepsy> .

obo:MP_0001847 a rdfs:Class ;
  rdfs:label "brain inflammation" ;
  rdfs:comment "local accumulation of fluid, plasma proteins, and leukocytes in the brain" ;
  rdfs:subClassOf obo:MP_0006082 .

obo:MONDO_0016705 a rdfs:Class ;
  rdfs:label "angiocentric glioma" ;
  rdfs:comment "Angiocentric glioma (AG) is an extremely rare slow-growing glial neoplasm of the central nervous system, usually arising in a superficial location in the cerebrum, affecting all ages and both sexes, and characterized by intractable seizures and headaches, with most cases being cured by surgical incision alone and therefore having a good prognosis." ;
  rdfs:seeAlso <http://www.case.edu/EpSO.owl#AngiocentricGlioma> ;
  rdfs:subClassOf obo:MONDO_0021637 .

obo:DOID_3133 a rdfs:Class ;
  rdfs:label "acute porphyria" ;
  rdfs:comment "A porphyria that has_symptom abdominal pain, has_symptom neuropathy, has_symptom autonomic instability and has_symptom psychosis." ;
  rdfs:seeAlso <https://www.epilepsy.com/learn/professionals/co-existing-disorders/metabolic-disorders/inborn-errors/hepatic-porphyria> ;
  rdfs:subClassOf obo:DOID_13268 .

obo:HP_0032659 a rdfs:Class ;
  rdfs:label "Non-convulsive status epilepticus with coma" ;
  rdfs:comment "A type of status epilepticus without prominent motor symptoms and in the presence of coma." ;
  rdfs:subClassOf obo:HP_0031475 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#absence_seizure_model> a rdfs:Class ;
  rdfs:label "absence seizure model" ;
  rdfs:subClassOf obo:NCIT_C19272 .

obo:UBERON_0002308 a rdfs:Class ;
  rdfs:label "nucleus of brain" ;
  rdfs:comment "A neural nucleus that is part of the brain." ;
  rdfs:subClassOf obo:UBERON_0000125 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#rotational_horizontal> a rdfs:Class ;
  rdfs:label "rotational horizontal" ;
  rdfs:seeAlso <https://www.aafp.org/afp/2006/0115/p244.html> ;
  rdfs:subClassOf obo:SYMP_0000399 .

obo:UBERON_0001890 a rdfs:Class ;
  rdfs:label "forebrain" ;
  rdfs:comment "The most anterior region the brain including both the telencephalon and diencephalon." ;
  rdfs:seeAlso <http://www.case.edu/EpSO.owl#Forebrain> ;
  rdfs:subClassOf obo:UBERON_0002616 .

obo:NBO_0000391 a rdfs:Class ;
  rdfs:label "startle reflex" ;
  rdfs:comment "\"An action or movement due to the application of a sudden unexpected stimulus.\" [wikipedia:Startle_reflex]" ;
  rdfs:subClassOf obo:NBO_0000389 .

obo:MFOMD_0000138 a rdfs:Class ;
  rdfs:label "psychosis" ;
  rdfs:comment "Symptom or feature of mental illness typically characterized by radical changes in personality, impaired functioning, and a distorted or nonexistent sense of objective reality." ;
  rdfs:seeAlso <https://www.epilepsy.com/learn/challenges-epilepsy/moods-and-behavior/mood-and-behavior-101/psychosis> ;
  rdfs:subClassOf obo:MFOMD_0000024 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#object_spatial_inclination> a rdfs:Class ;
  rdfs:label "object spatial inclination" ;
  rdfs:subClassOf obo:HP_0000504 .

obo:OMIT_0001932 a rdfs:Class ;
  rdfs:label "Alpha Rhythm" ;
  rdfs:seeAlso <http://www.case.edu/EpSO.owl#AlphaRhythm> , <https://emedicine.medscape.com/article/1139332-overview#a1> ;
  rdfs:subClassOf obo:OMIT_0027154 .

obo:DOID_8778 a rdfs:Class ;
  rdfs:label "Crohn's disease" ;
  rdfs:comment "An intestinal disease that involves inflammation located_in intestine." ;
  rdfs:seeAlso <https://www.epilepsy.com/learn/professionals/co-existing-disorders/inflammatory-disorders> ;
  rdfs:subClassOf obo:DOID_0050589 .

obo:MONDO_0007530 a rdfs:Class ;
  rdfs:label "electroencephalographic peculiarity: 14 and 6 per sec. positive spike phenomenon" ;
  rdfs:seeAlso <http://www.case.edu/EpSO.owl#Fourteen-SixHertzPositiveBurst> ;
  rdfs:subClassOf obo:DOID_630 .

obo:DOID_5656 a rdfs:Class ;
  rdfs:label "cranial nerve disease" ;
  rdfs:comment "A neuropathy that is located_in one of the twelve cranial nerves." ;
  rdfs:subClassOf obo:DOID_870 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#macro-scale_model> a rdfs:Class ;
  rdfs:label "macro-scale model" ;
  rdfs:subClassOf <https://bio.scai.fraunhofer.de/ontology/epilepsy#deterministic_model> .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#ducky_mouse> a rdfs:Class ;
  rdfs:label "ducky mouse" ;
  rdfs:subClassOf <https://bio.scai.fraunhofer.de/ontology/epilepsy#absence_seizure_model> .

obo:DOID_4543 a rdfs:Class ;
  rdfs:label "retrograde amnesia" ;
  rdfs:comment "An amnestic disorder that involves a loss of one's pre-existing memories to conscious recollection." ;
  rdfs:subClassOf obo:DOID_10914 .

obo:NBO_0000644 a rdfs:Class ;
  rdfs:label "voluntary movement behavior phenotype" ;
  rdfs:comment "\"Observable characteristic of behavior related to movements executed with intent.\" [NBO:GVG]" ;
  rdfs:subClassOf obo:NBO_0000568 .

obo:NBO_0000359 a rdfs:Class ;
  rdfs:label "terrestrial locomotory behavior" ;
  rdfs:comment "\"Behavior associated with surface locomotion.\" [NBO:GVG]" ;
  rdfs:subClassOf obo:NBO_0000013 .

obo:DOID_6621 a rdfs:Class ;
  rdfs:label "cerebral angioma" ;
  rdfs:comment "A brain angioma that is characterized by vascular abnormalities that develops from cranial and spinal blood vasculature, has_material_basis_in abnormally proliferating cells, derives_from endothelial cells in and about the vascular lumen." ;
  rdfs:subClassOf obo:MONDO_0024291 .

obo:NBO_0000475 a rdfs:Class ;
  rdfs:label "dyssomnia" ;
  rdfs:comment "\"A pathological sleeping behavior related to the initiating or maintaining sleep or of excessive sleepiness and are characterized by a disturbance in the amount, quality, or timing of sleep.\" [wikipedia:Dyssomnia]" ;
  rdfs:subClassOf obo:NBO_0000419 .

obo:NCIT_C16033 a rdfs:Class ;
  rdfs:label "Follow-Up" ;
  rdfs:comment "The process by which information about the health status of an individual is obtained after a study has officially closed; an activity that continues something that has already begun or that repeats something that has already been done." ;
  rdfs:subClassOf obo:OBI_0000011 .

obo:MFOMD_0000024 a rdfs:Class ;
  rdfs:label "pathological mental process" ;
  rdfs:subClassOf obo:OGMS_0000061 .

obo:CLO_0037307 a rdfs:Class ;
  rdfs:label "induced pluripotent stem cell line cell" ;
  rdfs:subClassOf obo:BFO_0000040 .

obo:HP_0002138 a rdfs:Class ;
  rdfs:label "Subarachnoid hemorrhage" ;
  rdfs:comment "Hemorrhage occurring between the arachnoid mater and the pia mater." ;
  rdfs:seeAlso <http://www.case.edu/EpSO.owl#SubarachnoidHemorrhage> ;
  rdfs:subClassOf obo:HP_0001342 .

obo:HP_0004363 a rdfs:Class ;
  rdfs:label "Abnormal circulating calcium concentration" ;
  rdfs:comment "Any deviation from the normal concentration of calcium in the blood circulation." ;
  rdfs:subClassOf obo:HP_0010927 .

obo:DOID_9091 a rdfs:Class ;
  rdfs:label "REM sleep behavior disorder" ;
  rdfs:comment "A sleep disorder that involves abnormal behavior including the acting out of violent or dramatic dreams during the sleep phase with rapid eye movement." ;
  rdfs:seeAlso <http://www.case.edu/EpSO.owl#RapidEyeMovementBehaviorDisorder> ;
  rdfs:subClassOf obo:DOID_535 .

obo:NBO_0000131 a rdfs:Class ;
  rdfs:label "alcohol consumption" ;
  rdfs:comment "\"A drinking behavior associated with the intake of alcohol.\" [NBO:GVG]" ;
  rdfs:seeAlso <https://www.epilepsy.org.uk/info/daily-life/alcohol> ;
  rdfs:subClassOf obo:NBO_0000130 .

obo:OAE_0001551 a rdfs:Class ;
  rdfs:label "brain AE" ;
  rdfs:comment "an adverse event that occurs in brain. " ;
  rdfs:subClassOf obo:OAE_0000001 .

obo:HP_0000118 a rdfs:Class ;
  rdfs:label "Phenotypic abnormality" ;
  rdfs:comment "A phenotypic abnormality." ;
  rdfs:subClassOf obo:BFO_0000019 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#anterior_frontopolar_cortex> a rdfs:Class ;
  rdfs:label "anterior frontopolar cortex" ;
  rdfs:subClassOf obo:UBERON_0000956 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#urine_organic_acid_test> a rdfs:Class ;
  rdfs:label "urine organic acid test" ;
  rdfs:subClassOf obo:MMO_0000147 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#seizure_not_necessarily_requiring_a_diagnosis_of_epilepsy> a rdfs:Class ;
  rdfs:label "seizure not necessarily requiring a diagnosis of epilepsy" ;
  rdfs:subClassOf obo:SYMP_0000124 .

obo:DOID_0050989 a rdfs:Class ;
  rdfs:label "episodic ataxia type 1" ;
  rdfs:comment "An episodic ataxia that is characterized by periodic ataxia and frequent myokymic discharges, and has_material_basis_in autosomal dominant inheritance of mutation in the potassium channel gene KCNA1." ;
  rdfs:subClassOf obo:DOID_963 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#neonatal_hypoxia_model> a rdfs:Class ;
  rdfs:label "neonatal hypoxia model" ;
  rdfs:subClassOf obo:NCIT_C19021 .

obo:DOID_12568 a rdfs:Class ;
  rdfs:label "dyscalculia" ;
  rdfs:comment "A learning disability involving a math disability can cause such difficulties as learning math concepts (such as quantity, place value, and time), difficulty memorizing math facts, difficulty organizing numbers, and understanding how problems are organized on the page." ;
  rdfs:seeAlso <https://www.epilepsydiagnosis.org/seizure/cognitive-overview.html> ;
  rdfs:subClassOf obo:DOID_8927 .

obo:UBERON_0000055 a rdfs:Class ;
  rdfs:label "vessel" ;
  rdfs:comment "A tubular structure that contains, conveys body fluid, such as blood or lymph." ;
  rdfs:subClassOf obo:UBERON_0004111 .

obo:CMO_0000064 a rdfs:Class ;
  rdfs:label "blood enzyme activity level" ;
  rdfs:subClassOf obo:CMO_0002498 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#focal_emotional_seizure_with_pleasure> a rdfs:Class ;
  rdfs:label "focal emotional seizure with pleasure" ;
  rdfs:seeAlso <http://www.medlink.com/article/focal_sensory_seizures_with_experiential_symptoms> ;
  rdfs:subClassOf obo:HP_0025613 .

obo:NCIT_C15747 a rdfs:Class ;
  rdfs:label "Supportive Care" ;
  rdfs:comment "Supportive care is that which helps the patient and their family to cope with cancer and treatment of it from pre-diagnosis, through the process of diagnosis and treatment, to cure, continuing illness or death and into bereavement. It helps the patient to maximize the benefits of treatment and to live as well as possible with the effects of the disease. Supportive therapy may provide a patient with friendship, encouragement, practical advice such as access to community resources or how to develop a more active social life, vocational counseling, suggestions for minimizing friction with family members, and, above all, hope that the life of the patient may be improved. In all situations, supportive therapy involves the teaching of such life skills as managing medication, learning to socialize, handling finances, and getting a job." ;
  rdfs:subClassOf obo:OGMS_0000112 .

obo:DOID_0050117 a rdfs:Class ;
  rdfs:label "disease by infectious agent" ;
  rdfs:comment "A disease that is the consequence of the presence of pathogenic microbial agents, including pathogenic viruses, pathogenic bacteria, fungi, protozoa, multicellular parasites, and aberrant proteins known as prions." ;
  rdfs:subClassOf obo:DOID_4 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#speech_interrupted> a rdfs:Class ;
  rdfs:label "speech interrupted" ;
  rdfs:seeAlso <https://www.epilepsy.com/article/2014/3/types-language-problems-epilepsy> ;
  rdfs:subClassOf obo:SYMP_0000387 .

obo:HP_0031475 a rdfs:Class ;
  rdfs:label "Status epilepticus without prominent motor symptoms" ;
  rdfs:comment "There is inconclusive evidence to precisely define the duration of the seizure; however, based on current evidence an operational threshold of 10 minutes is appropriate as beyond this a seizure is likely to be more prolonged. The individual may or may not be aware or in coma." ;
  rdfs:subClassOf obo:HP_0002133 .

obo:NCIT_C123667 a rdfs:Class ;
  rdfs:label "Montreal Cognitive Assessment Functional Test" ;
  rdfs:comment "A standardized rating scale developed by Ziad Nasreddine in 1996 to screen for mild cognitive dysfunction and impairment. This instrument assesses the following cognitive domains: attention and concentration, executive functions, memory, language, visuoconstructional skills, conceptual thinking, calculations, and orientation." ;
  rdfs:subClassOf obo:NCIT_C20993 .

obo:UBERON_0006478 a rdfs:Class ;
  rdfs:label "Brodmann (1909) area 37" ;
  rdfs:comment "Brodmann area 37, or BA37, is part of the temporal cortex in the human brain. This area is known as occipitotemporal area 37 (H). It is a subdivision of the cytoarchitecturally defined temporal region of cerebral cortex. It is located primarily in the caudal portions of the fusiform gyrus and inferior temporal gyrus on the mediobasal and lateral surfaces at the caudal extreme of the temporal lobe. Cytoarchitecturally it is bounded caudally by the peristriate Brodmann area 19, rostrally by the inferior temporal area 20 and middle temporal area 21 and dorsally on the lateral aspect of the hemisphere by the angular area 39 (H) (Brodmann-1909)." ;
  rdfs:subClassOf obo:UBERON_0013529 .

obo:BFO_0000030 a rdfs:Class ;
  rdfs:label "object" ;
  rdfs:subClassOf obo:BFO_0000040 .

obo:NCIT_C50531 a rdfs:Class ;
  rdfs:label "Dialysis Encephalopathy" ;
  rdfs:comment "A severe, often fatal encephalopathy which has been attributed to accumulation in the brain of aluminum from dialysate prepared with inadequately purified water." ;
  rdfs:seeAlso <https://www.epilepsy.com/learn/professionals/co-existing-disorders/renal-disorders/dialysis-encephalopathy-syndrome> ;
  rdfs:subClassOf obo:NCIT_C26920 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#non-surgical_stimulation> a rdfs:Class ;
  rdfs:label "non-surgical stimulation" ;
  rdfs:subClassOf obo:OGMS_0000112 .

obo:DOID_13515 a rdfs:Class ;
  rdfs:label "tuberous sclerosis" ;
  rdfs:comment "A syndrome that is characterized by the growth of numerous noncancerous tumors in many parts of the body." ;
  rdfs:subClassOf obo:NCIT_C84834 .

obo:GO_0071626 a rdfs:Class ;
  rdfs:label "mastication" ;
  rdfs:comment "The process of biting and mashing food with the teeth prior to swallowing." ;
  rdfs:subClassOf obo:GO_0022600 .

obo:NCIT_C16358 a rdfs:Class ;
  rdfs:label "Body Mass Index" ;
  rdfs:comment "An individual's weight in kilograms divided by the square of the height in meters." ;
  rdfs:subClassOf obo:NCIT_C19332 .

obo:UBERON_0001020 a rdfs:Class ;
  rdfs:label "nervous system commissure" ;
  rdfs:comment "Axon tract that crosses the midline of the central nervous system[NIF, modified]. In the context of Drosophila refers to a broad band of axons connecting equivalent neuropils each side of the brain[FBbt]." ;
  rdfs:subClassOf obo:UBERON_0001018 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#flurothyl_model> a rdfs:Class ;
  rdfs:label "flurothyl model" ;
  rdfs:subClassOf <https://bio.scai.fraunhofer.de/ontology/epilepsy#convulsant_drug_model> .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#focal_motor_seizure_with_negative_myoclonus> a rdfs:Class ;
  rdfs:label "focal motor seizure with negative myoclonus" ;
  rdfs:subClassOf obo:HP_0011153 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#hyper-cyanotic_spell> a rdfs:Class ;
  rdfs:label "hyper-cyanotic spell" ;
  rdfs:subClassOf obo:HP_0001279 .

obo:UBERON_0005340 a rdfs:Class ;
  rdfs:label "dorsal telencephalic commissure" ;
  rdfs:comment "A fiber tracts that connect the dorsal region of the two cerebral hemispheres and span the longitudinal fissure, including the corpus callosum and hippocampal commissure[MP]." ;
  rdfs:subClassOf obo:UBERON_0019294 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#sharp_wave> a rdfs:Class ;
  rdfs:label "sharp wave" ;
  rdfs:seeAlso <http://www.case.edu/EpSO.owl#SharpWave> ;
  rdfs:subClassOf <https://bio.scai.fraunhofer.de/ontology/epilepsy#transient> .

obo:OGMS_0000123 a rdfs:Class ;
  rdfs:label "clinical data item" ;
  rdfs:comment "a data item that is about a patient and is the specified output of a health care process assay or diagnostic process" ;
  rdfs:subClassOf obo:IAO_0000027 .

<https://bio.scai.fraunhofer.de/ontology/0000505> a rdfs:Class ;
  rdfs:label "seizure network" ;
  rdfs:subClassOf obo:NCIT_C17429 .

obo:PW_0000007 a rdfs:Class ;
  rdfs:label "mitogen activated protein kinase signaling pathway" ;
  rdfs:comment "The mitogen -activated protein kinase pathway groups several serine/threonine protein kinases mediated cascades in response to a number of extracellular stimuli.  A characteristic feature of these cascades is the presence of at least three kinases in series leading to the activation of a multifunctional MAP kinase." ;
  rdfs:subClassOf obo:GO_0007165 .

<https://bio.scai.fraunhofer.de/ontology/0000420> a rdf:Property ;
  rdfs:label "isCellularProcessFor" ;
  rdfs:range <https://w3id.org/linkml/Any> .

obo:HP_0025031 a rdfs:Class ;
  rdfs:label "Abnormality of the digestive system" ;
  rdfs:comment "Any anomaly of the digestive system, a collection of organs that is made up of the gastrointestinal tract and the liver, pancreas, and gallbladder. The gastrointestinal tract is a series of hollow organs joined in a long, twisting tube from the mouth to the anus, including the mouth, esophagus, stomach, small intestine, large intestine and anus." ;
  rdfs:subClassOf obo:HP_0000118 .

obo:UBERON_0013554 a rdfs:Class ;
  rdfs:label "Brodmann (1909) area 23" ;
  rdfs:comment "The term area 23 of Brodmann-1909 refers to a subdivision of the cerebral cortex of the guenon defined on the basis of cytoarchitecture. Brodmann regarded it as topographically and cytoarchitecturally homologous to the combined ventral posterior cingulate area 23 and dorsal posterior cingulate area 31 of the human (Brodmann-1909). Distinctive Features (Brodmann-1905): the cortex is relatively thin; smaller cells predominate; the cell density of the multiform layer (VI) is great, producing a distinct boundary with the subcortical white matter; the internal granular layer (IV) is rather well developed; the internal pyramidal layer (V) contains a dense population of round, medium-sized ganglion cells concentrated at the border with layer IV; layers V and VI are narrow with a distinct mutual boundary.nn* Definition Source NeuroNames" ;
  rdfs:subClassOf obo:UBERON_0013529 .

obo:HP_0100832 a rdfs:Class ;
  rdfs:label "Vitreous floaters" ;
  rdfs:comment "Deposits of various size, shape, consistency, refractive index, and motility within the eye's vitreous humour, which is normally transparent." ;
  rdfs:subClassOf obo:HP_0000504 , obo:HP_0004327 .

obo:NCIT_C127816 a rdfs:Class ;
  rdfs:label "WHO Grade III Glioma" ;
  rdfs:comment "A group of malignant gliomas that includes anaplastic astrocytoma, anaplastic oligodendroglioma, anaplastic oligoastrocytoma, and anaplastic ependymoma." ;
  rdfs:seeAlso <http://www.case.edu/EpSO.owl#AnaplasticGlioma> ;
  rdfs:subClassOf obo:MONDO_0015917 .

obo:DOID_150 a rdfs:Class ;
  rdfs:label "disease of mental health" ;
  rdfs:comment "A disease that involves a psychological or behavioral pattern generally associated with subjective distress or disability that occurs in an individual, and which are not a part of normal development or culture." ;
  rdfs:subClassOf obo:DOID_4 .

obo:HP_0032039 a rdfs:Class ;
  rdfs:label "Abnormality of the ocular adnexa" ;
  rdfs:comment "An anomaly of the adjacent structures (i.e., adnexa) of the eye, defined as the lacrimal apparatus, the extraocular muscles and the eyelids, eyelashes, eyebrows and the conjunctiva." ;
  rdfs:subClassOf obo:HP_0000315 .

obo:HP_0002086 a rdfs:Class ;
  rdfs:label "Abnormality of the respiratory system" ;
  rdfs:comment "An abnormality of the respiratory system, which include the airways, lungs, and the respiratory muscles." ;
  rdfs:subClassOf obo:HP_0000118 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#mesial_temporal_lobe_seizure_including_hippocampus> a rdfs:Class ;
  rdfs:label "mesial temporal lobe seizure including hippocampus" ;
  rdfs:subClassOf <https://bio.scai.fraunhofer.de/ontology/epilepsy#temporal_lobe_seizure> .

obo:UBERON_0007193 a rdfs:Class ;
  rdfs:label "orbital gyrus" ;
  rdfs:comment "The inferior or orbital surface of the frontal lobe is concave, and rests on the orbital plate of the frontal bone. It is divided into four orbital gyri by a well-marked H-shaped orbital sulcus. These are named, from their position, the medial, anterior, lateral, and posterior orbital gyri. The medial orbital gyrus presents a well-marked antero-posterior sulcus, the olfactory sulcus, for the olfactory tract; the portion medial to this is named the straight gyrus, and is continuous with the superior frontal gyrus on the medial surface." ;
  rdfs:subClassOf obo:UBERON_0000200 .

obo:HP_0004374 a rdfs:Class ;
  rdfs:label "Hemiplegia/hemiparesis" ;
  rdfs:comment "Loss of strength in the arm, leg, and sometimes face on one side of the body. Hemiplegia refers to a severe or complete loss of strength, whereas hemiparesis refers to a relatively mild loss of strength." ;
  rdfs:subClassOf obo:HP_0010549 .

obo:NBO_0000686 a rdfs:Class ;
  rdfs:label "provoked seizure" ;
  rdfs:comment "\"Paroxysmal events that mimic an epileptic seizure but do not involve abnormal, rhythmic discharges of cortical neurons.\" [wikipedia:http\\://en.wikipedia.org/wiki/Non-epileptic_seizure]" ;
  rdfs:subClassOf obo:SYMP_0000124 .

obo:HP_0032663 a rdfs:Class ;
  rdfs:label "Focal motor status epilepticus" ;
  rdfs:comment "Status epilepticus with focal motor signs originating within networks limited to one hemisphere. Involves musculature in any form. The motor event could consist of an increase (positive) or decrease (negative) in muscle contraction to produce a movement." ;
  rdfs:subClassOf obo:HP_0032658 .

obo:BFO_0000006 a rdfs:Class ;
  rdfs:label "spatial region" ;
  rdfs:subClassOf obo:BFO_0000141 .

obo:MONDO_0019487 a rdfs:Class ;
  rdfs:label "epilepsy with myoclonic absences" ;
  rdfs:subClassOf obo:MONDO_0020072 .

obo:HP_0000079 a rdfs:Class ;
  rdfs:label "Abnormality of the urinary system" ;
  rdfs:comment "An abnormality of the urinary system." ;
  rdfs:subClassOf obo:HP_0000119 .

obo:DOID_3329 a rdfs:Class ;
  rdfs:label "benign epilepsy with centrotemporal spikes" ;
  rdfs:seeAlso <http://www.case.edu/EpSO.owl#BenignChildhoodEpilepsyWithCentrotemporalSpikes> ;
  rdfs:subClassOf obo:MONDO_0020072 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#sinusoidal_wave> a rdfs:Class ;
  rdfs:label "sinusoidal wave" ;
  rdfs:seeAlso <https://www.medicine.mcgill.ca/physio/vlab/biomed_signals/eeg_n.htm> ;
  rdfs:subClassOf obo:OMIT_0027154 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#cingulate_epilepsy> a rdfs:Class ;
  rdfs:label "cingulate epilepsy" ;
  rdfs:seeAlso <http://www.case.edu/EpSO.owl#CingulateEpilepsy> ;
  rdfs:subClassOf <https://bio.scai.fraunhofer.de/ontology/epilepsy#simple_focal_seizure> .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#person_hallucination> a rdfs:Class ;
  rdfs:label "person hallucination" ;
  rdfs:subClassOf obo:NBO_0000609 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#focal_autonomic_seizure_with_pallor/flushing> a rdfs:Class ;
  rdfs:label "focal autonomic seizure with pallor/flushing" ;
  rdfs:seeAlso <https://www.epilepsydiagnosis.org/seizure/autonomic-overview.html> , <http://epilepsyontario.org/about-epilepsy/types-of-seizures/simple-partial-seizures/> ;
  rdfs:subClassOf obo:HP_0011154 .

obo:HP_0004329 a rdfs:Class ;
  rdfs:label "Abnormal posterior eye segment morphology" ;
  rdfs:comment "The posterior segment comprises the anterior hyaloid membrane and all of the optical structures behind it: the vitreous humor, retina, choroid, and optic nerve." ;
  rdfs:subClassOf obo:HP_0012372 .

obo:DOID_0060091 a rdfs:Class ;
  rdfs:label "cardiovascular organ benign neoplasm" ;
  rdfs:comment "An organ system benign neoplasm disease located_in the blood, heart, blood vessels or the lymphatic system." ;
  rdfs:subClassOf obo:DOID_1287 .

obo:HP_0001977 a rdfs:Class ;
  rdfs:label "Abnormal thrombosis" ;
  rdfs:comment "Venous or arterial thrombosis (formation of blood clots) of spontaneous nature and which cannot be fully explained by acquired risk (e.g. atherosclerosis)." ;
  rdfs:subClassOf obo:HP_0001871 .

obo:PW_0000572 a rdfs:Class ;
  rdfs:label "brain-derived neurotrophic factor signaling pathway" ;
  rdfs:comment "Brain-derived neurotrophic factor (BDNF) signaling pathway plays important roles in the growth, differentiation and survival of neurons, particularly the striatal neurons. BDNF signals via the tropomyosin-related kinase receptor type B (TrkB) to activate PKC, PI3K-AKT and MAPK/ERK intracellular pathways. Impaired BDNF signaling contributes to the pathogenesis of conditions such as Huntington Disease (HD) and psychiatric disorders. Upregulation on the other hand, is associated with several malignancies." ;
  rdfs:subClassOf obo:GO_0007165 .

obo:HP_0011175 a rdfs:Class ;
  rdfs:label "Versive seizures" ;
  rdfs:comment "Tonic seizures with a sustained, forced conjugate ocular, cephalic and/or truncal rotation or lateral deviation from the midline." ;
  rdfs:subClassOf obo:SYMP_0000124 .

obo:UBERON_0000446 a rdfs:Class ;
  rdfs:label "septum of telencephalon" ;
  rdfs:comment "Gray matter structure located on the midline of the forebrain consisting of the septum pellucidum (in some species) and the septal nuclei (Heimer, 1996)." ;
  rdfs:subClassOf obo:UBERON_0005401 .

obo:SYMP_0000837 a rdfs:Class ;
  rdfs:label "chronic pain" ;
  rdfs:comment "Chronic pain is a pain that can range from mild to severe, and continues beyond the expected healing phase." ;
  rdfs:subClassOf obo:SYMP_0000099 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#sleep_deprived_electroencephalography> a rdfs:Class ;
  rdfs:label "sleep deprived electroencephalography" ;
  rdfs:subClassOf obo:OBI_0002186 .

obo:PW_0000388 a rdfs:Class ;
  rdfs:label "Reelin signaling pathway" ;
  rdfs:comment "The reelin signaling pathway regulates neuronal positioning and may also play a role in synaptic plasticity. The reelin gene appears to be downregulated in schizophrenic brains but the link between the reelin pathway and the disease remains to be established." ;
  rdfs:subClassOf obo:GO_0007165 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#primary_sensorimotor_cortex_seizure> a rdfs:Class ;
  rdfs:label "primary sensorimotor cortex seizure" ;
  rdfs:subClassOf <https://bio.scai.fraunhofer.de/ontology/epilepsy#frontal_lobe_seizure> .

obo:CMO_0001241 a rdfs:Class ;
  rdfs:label "cerebrospinal fluid chemistry measurement" ;
  rdfs:seeAlso <https://link.springer.com/article/10.1007/BF02075764> ;
  rdfs:subClassOf obo:CMO_0001240 .

obo:HP_0007359 a rdfs:Class ;
  rdfs:label "Focal-onset seizure" ;
  rdfs:comment "Seizures of which initial semiology indicates, or is consistent with, initial activation of only part of one cerebral hemisphere." ;
  rdfs:subClassOf <https://bio.scai.fraunhofer.de/ontology/epilepsy#seizure_classification> .

obo:MMO_0000024 a rdfs:Class ;
  rdfs:label "ultrasound method" ;
  rdfs:comment "A technique which uses the visualization of deep structures of the body by recording the reflections of pulses of ultrasonic waves directed into the tissues." ;
  rdfs:subClassOf obo:ERO_0001312 .

obo:OMIT_0019406 a rdfs:Class ;
  rdfs:label "Aromatherapy" ;
  rdfs:subClassOf obo:NCIT_C15308 .

obo:MONDO_0024361 a rdfs:Class ;
  rdfs:label "circadian rhythm sleep disorder" ;
  rdfs:comment "A persistent or recurrent pattern of sleep disruption that is primarily due to an alteration of the circadian system or to a misalignment between the endogenous circadian rhythm and the sleep-wake schedule required by an individual's physical environment or social or professional schedule.(DSM IV)" ;
  rdfs:subClassOf obo:NBO_0000419 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#deterministic_model> a rdfs:Class ;
  rdfs:label "deterministic model" ;
  rdfs:subClassOf <https://bio.scai.fraunhofer.de/ontology/epilepsy#in_silico_model> .

obo:MFOMD_0000113 a rdfs:Class ;
  rdfs:label "flashback" ;
  rdfs:comment """
The recurrence of a memory, feeling, or perceptual experience from the past.


DSM-IV-TR (american Psychiatric Association)""" ;
  rdfs:seeAlso <https://link.springer.com/content/pdf/10.1684/epd.2013.0550.pdf> ;
  rdfs:subClassOf obo:MFOMD_0000024 .

obo:MFOEM_000034 a rdfs:Class ;
  rdfs:label "joy" ;
  rdfs:comment "A pleasant, positive emotion which arises in safe and familiar circumstances, when people have made progress towards important personal goals, especially when the progress is better than expected. [Source: OCEAS]" ;
  rdfs:subClassOf obo:MFOEM_000042 .

obo:DOID_13365 a rdfs:Class ;
  rdfs:label "reading disorder" ;
  rdfs:comment "A learning disability involing difficulty reading resulting primarily from neurological factors which affect any part of the reading process." ;
  rdfs:subClassOf obo:DOID_8927 .

obo:CMO_0000036 a rdfs:Class ;
  rdfs:label "blood cell measurement" ;
  rdfs:subClassOf obo:CMO_0000035 , obo:CMO_0000227 .

obo:DOID_0050736 a rdfs:Class ;
  rdfs:label "autosomal dominant disease" ;
  rdfs:comment "An autosomal genetic disease that is characterized by the presence of one disease-associated mutation of a gene which is sufficient to cause the disease." ;
  rdfs:subClassOf obo:DOID_0050739 .

obo:UBERON_0002314 a rdfs:Class ;
  rdfs:label "midbrain tectum" ;
  rdfs:comment "Dorsal part of the midbrain, consisting of the superior and inferior colliculi and the pretectal nuclei (MM)." ;
  rdfs:subClassOf obo:UBERON_0002616 .

obo:BFO_0000182 a rdfs:Class ;
  rdfs:label "history" ;
  rdfs:subClassOf obo:BFO_0000015 .

obo:CMO_0000001 a rdfs:Class ;
  rdfs:label "cardiovascular measurement" ;
  rdfs:subClassOf obo:CMO_0000000 .

obo:HP_0100261 a rdfs:Class ;
  rdfs:label "Abnormal tendon morphology" ;
  rdfs:comment "An abnormality of the structure or form of the tendons, also often called sinews." ;
  rdfs:subClassOf obo:HP_0011842 .

obo:UBERON_0006482 a rdfs:Class ;
  rdfs:label "Brodmann (1909) area 45" ;
  rdfs:comment "Part of the cytoarchitecturally defined frontal region of cerebral cortex. In the human, it occupies the triangular part of the inferior frontal gyrus (human) and, surrounding the anterior horizontal limb of the lateral sulcus (human), a portion of the orbital part of the inferior frontal gyrus (human). Bounded caudally by the anterior ascending limb of the lateral sulcus (human), it borders on the insula in the depth of the lateral sulcus. Cytoarchitectonically it is bounded caudally by the opercular area 44, rostrodorsally by the area 46 of Brodmann (human) and ventrally by the area 47 of Brodmann (human) (Brodmann-1909) (Adapted from Brain Info)" ;
  rdfs:subClassOf obo:UBERON_0013529 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#benign_focal_epileptiform_discharge_of_childhood> a rdfs:Class ;
  rdfs:label "benign focal epileptiform discharge of childhood" ;
  rdfs:seeAlso <http://www.case.edu/EpSO.owl#BenignFocalEpileptiformDischargeofChildhood> ;
  rdfs:subClassOf obo:HP_0025373 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#parieto-occipital_junction_seizure> a rdfs:Class ;
  rdfs:label "parieto-occipital junction seizure" ;
  rdfs:subClassOf <https://bio.scai.fraunhofer.de/ontology/epilepsy#occipital_lobe_seizure> , <https://bio.scai.fraunhofer.de/ontology/epilepsy#parietal_lobe_seizure> .

obo:NBO_0000739 a rdfs:Class ;
  rdfs:label "dacrystic epilepsy" ;
  rdfs:comment "\"A type of epilepsy that is characterised a sudden paroxysmal crying.\" [NBO:<new dbxref>, NBO:GVG]" ;
  rdfs:subClassOf obo:DOID_1826 .

obo:OBI_0000047 a rdfs:Class ;
  rdfs:label "processed material" ;
  rdfs:comment "Is a material entity that is created or changed during material processing." ;
  rdfs:subClassOf obo:BFO_0000040 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#perinatal_insult> a rdfs:Class ;
  rdfs:label "perinatal insult" ;
  rdfs:subClassOf obo:NCIT_C17103 .

obo:HP_0011164 a rdfs:Class ;
  rdfs:label "Vegetative auras" ;
  rdfs:comment "A sensation consistent with involvement of the autonomic nervous system, including cardiovascular, gastrointestinal, sudomotor, vasomotor and thermoregulatory functions." ;
  rdfs:seeAlso <http://www.case.edu/EpSO.owl#AutonomicAura> ;
  rdfs:subClassOf obo:SYMP_0000124 .

obo:OMIT_0008800 a rdfs:Class ;
  rdfs:label "Kindling model" ;
  rdfs:subClassOf obo:NCIT_C16866 .

obo:HP_0011203 a rdfs:Class ;
  rdfs:label "EEG with abnormally slow frequencies" ;
  rdfs:comment "EEG with abnormally slow frequencies." ;
  rdfs:subClassOf obo:HP_0002353 .

obo:OGMS_0000112 a rdfs:Class ;
  rdfs:label "therapeutic procedure" ;
  rdfs:comment "A treatment whose completion is hypothesized by a health care provider to eliminate a disorder or to alleviate the signs and symptoms of a disorder or pathological process." ;
  rdfs:subClassOf obo:OGMS_0000090 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#non_dominant_parietal_cortex_seizure> a rdfs:Class ;
  rdfs:label "non dominant parietal cortex seizure" ;
  rdfs:subClassOf <https://bio.scai.fraunhofer.de/ontology/epilepsy#parietal_lobe_seizure> .

obo:DOID_3068 a rdfs:Class ;
  rdfs:label "glioblastoma multiforme" ;
  rdfs:comment "An astrocytoma characterized by the presence of small areas of necrotizing tissue that is surrounded by anaplastic cells as well as the presence of hyperplastic blood vessels, and that has_material_basis_in abnormally proliferating cells derives_from multiple cell types including astrocytes and oligondroctyes." ;
  rdfs:seeAlso <http://www.case.edu/EpSO.owl#GlioblastomaMultiforme> ;
  rdfs:subClassOf obo:DOID_3069 .

obo:MP_0003965 a rdfs:Class ;
  rdfs:label "abnormal pituitary hormone level" ;
  rdfs:comment "aberration in the blood or tissue concentration of any of the hormones secreted by the pituitary" ;
  rdfs:subClassOf obo:MP_0003953 .

obo:NBO_0000002 a rdfs:Class ;
  rdfs:label "whole body movement" ;
  rdfs:subClassOf obo:NBO_0000338 .

obo:MONDO_0015247 a rdfs:Class ;
  rdfs:label "opsoclonus-myoclonus syndrome" ;
  rdfs:comment "Opsoclonus myoclonus syndrome (OMS) is a rare neuroinflammatory disease of paraneoplastic, parainfectious or idiopathic origin, characterized by opsoclonus, myoclonus, ataxia, and behavioral and sleep disorders." ;
  rdfs:subClassOf obo:MONDO_0017657 .

obo:PATO_0001018 a rdfs:Class ;
  rdfs:label "physical quality" ;
  rdfs:comment "A quality of a physical entity that exists through action of continuants at the physical level of organisation in relation to other entities." ;
  rdfs:subClassOf obo:PATO_0001241 .

obo:MONDO_0021638 a rdfs:Class ;
  rdfs:label "low grade astrocytic tumor" ;
  rdfs:comment "A grade I or grade II astrocytic tumor. This category includes pilocytic astrocytoma (grade I), subependymal giant cell astrocytoma (grade I), and diffuse astrocytoma (grade II)." ;
  rdfs:subClassOf obo:MONDO_0021637 .

obo:UBERON_0001894 a rdfs:Class ;
  rdfs:label "diencephalon" ;
  rdfs:comment "The division of the forebrain that develops from the foremost primary cerebral vesicle." ;
  rdfs:seeAlso <http://www.case.edu/EpSO.owl#Diencephalon> ;
  rdfs:subClassOf obo:UBERON_0002616 .

obo:HP_0000733 a rdfs:Class ;
  rdfs:label "Stereotypy" ;
  rdfs:comment "A stereotypy is a repetitive, simple movement that can be voluntarily suppressed. Stereotypies are typically simple back-and-forth movements such as waving of flapping the hands or arms, and they do not involve complex sequences or movement fragments. Movement is often but not always rhythmic and may involve fingers, wrists, or more proximal portions of the upper extremity. The lower extremity is not typically involved. Stereotypies are more commonly bilateral than unilateral." ;
  rdfs:subClassOf obo:MONDO_0017657 .

obo:DOID_14250 a rdfs:Class ;
  rdfs:label "Down syndrome" ;
  rdfs:comment "A chromosomal disease that is characterized by flat-looking facial features and weak muscle tone (hypotonia) in infancy and is caused by trisomy of all or a critical portion of chromosome 21 and is associated with intellectual disability." ;
  rdfs:subClassOf obo:MONDO_0019040 .

obo:HP_0011182 a rdfs:Class ;
  rdfs:label "Interictal epileptiform activity" ;
  rdfs:comment "Epileptiform activity refers to distinctive EEG waves or complexes distinguished from background activity found in in a proportion of human subjects with epilepsy, but which can also be found in subjects without seizures. Interictal epileptiform activity refers to such activity that occurs in the absence of a clinical or subclinical seizure." ;
  rdfs:subClassOf obo:HP_0025373 .

obo:OGMS_0000073 a rdfs:Class ;
  rdfs:label "diagnosis" ;
  rdfs:comment "The representation of a conclusion of a diagnostic process." ;
  rdfs:seeAlso <https://www.epilepsy.com/learn/diagnosing-epilepsy> , <http://www.case.edu/EpSO.owl#Diagnosis> ;
  rdfs:subClassOf obo:OGMS_0000123 .

obo:SYMP_0000530 a rdfs:Class ;
  rdfs:label "palpitation" ;
  rdfs:comment "Palpitation is a cardiovascykar system symptom characterized by an abnormal awareness of the beating of the heart,whether it is too slow, too fast, irregular, or at its normal frequency when excited by violent exertion, strong emotion, or disease." ;
  rdfs:subClassOf obo:SYMP_0000528 .

obo:MONDO_0013792 a rdfs:Class ;
  rdfs:label "intracerebral hemorrhage" ;
  rdfs:comment "Bleeding into one or both cerebral hemispheres including the basal ganglia and the cerebral cortex. It is often associated with hypertension and craniocerebral trauma." ;
  rdfs:seeAlso <http://www.case.edu/EpSO.owl#IntracerebralHemorrhage> ;
  rdfs:subClassOf obo:HP_0001342 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#benign_EEG_pattern> a rdfs:Class ;
  rdfs:label "benign EEG pattern" ;
  rdfs:seeAlso <http://www.case.edu/EpSO.owl#BenignEEGPattern> ;
  rdfs:subClassOf obo:OBI_0002186 .

obo:UBERON_0006474 a rdfs:Class ;
  rdfs:label "Brodmann (1909) area 30" ;
  rdfs:comment "Brodmann area 30, also known as agranular retrolimbic area 30, is a subdivision of the cytoarchitecturally defined retrosplenial region of the cerebral cortex. In the human it is located in the isthmus of cingulate gyrus. Cytoarchitecturally it is bounded internally by the granular retrolimbic area 29, dorsally by the ventral posterior cingulate area 23 and ventrolaterally by the ectorhinal area 36 (Brodmann-1909)." ;
  rdfs:subClassOf obo:UBERON_0013529 .

obo:NBO_0000675 a rdfs:Class ;
  rdfs:label "reflex seizure" ;
  rdfs:comment "\"A type of seizure generated by sudden sensor stimulation caused by the environment.\" [NBO:GVG]" ;
  rdfs:subClassOf obo:NBO_0000686 .

obo:GO_0007610 a rdfs:Class ;
  rdfs:label "behavior" ;
  rdfs:comment "The internally coordinated responses (actions or inactions) of animals (individuals or groups) to internal or external stimuli, via a mechanism that involves nervous system activity." ;
  rdfs:subClassOf obo:OGMS_0000060 .

obo:HP_0031785 a rdfs:Class ;
  rdfs:label "Abnormal eyelid movement" ;
  rdfs:comment "An abnormality in voluntary or involuntary eyelid movements or their control." ;
  rdfs:subClassOf obo:HP_0031879 .

obo:MONDO_0014708 a rdfs:Class ;
  rdfs:label "ring chromosome 14" ;
  rdfs:comment "Ring chromosome 14 syndrome is characterized by intellectual deficit, retinal and skin pigmentation disorders, seizures, and dysmorphic features, including flat occiput, epicanthal folds, downward slanting eyes, flat nasal bridge, upturned nostrils, short neck, and large low set ears." ;
  rdfs:subClassOf obo:MONDO_0019040 .

obo:HP_0012508 a rdfs:Class ;
  rdfs:label "Metamorphopsia" ;
  rdfs:comment "A visual anomaly in which images appear distorted. A grid of straight lines appears wavy and parts of the grid may appear blank." ;
  rdfs:seeAlso <http://www.case.edu/EpSO.owl#Metamorphopsia> ;
  rdfs:subClassOf obo:HP_0000504 .

obo:BFO_0000029 a rdfs:Class ;
  rdfs:label "site" ;
  rdfs:subClassOf obo:BFO_0000141 .

obo:UBERON_0002436 a rdfs:Class ;
  rdfs:label "primary visual cortex" ;
  rdfs:comment "A subdivision of the cytoarchitecturally defined occipital region of cerebral cortex in the human. Defined by the band of Gennari, which gives it the name striate (furrowed) area, it occupies the banks of the calcarine sulcus which are located in the cuneus and the lingual gyrus of the occipital lobe. Cytoarchitecturally it is bounded by the area 18 of Brodmann (human) which surrounds it ( Brodmann-1909 ). In the mouse ( Paxinos-2001 ) and the rat ( Swanson-1998 ) it is located on the dorsolateral surface of the cerebral hemisphere[BrainInfo]." ;
  rdfs:subClassOf obo:UBERON_0013529 , obo:UBERON_0035014 .

obo:UBERON_0001898 a rdfs:Class ;
  rdfs:label "hypothalamus" ;
  rdfs:comment "A specialized brain region of the ventral diencephalon arising near the end of the segmentation period; the embryonic hypothalamic region will give rise to the posterior pituitary gland as well as a number of brain nuclei. [ZFA]. One of the most important functions of the hypothalamus is to link the nervous system to the endocrine system via the pituitary gland (hypophysis).[Wikipedia]." ;
  rdfs:seeAlso <http://www.case.edu/EpSO.owl#HypothalamusZone> ;
  rdfs:subClassOf obo:UBERON_0002616 .

obo:NCIT_C98909 a rdfs:Class ;
  rdfs:label "Cyanotic Attacks in Children" ;
  rdfs:comment "Episodes of cyanosis that result from breath holding spells in response to anger or frustration, during childhood. These episodes usually resolve in a few seconds." ;
  rdfs:seeAlso <https://www.epilepsydiagnosis.org/epilepsy-imitators.html#breath-holding> ;
  rdfs:subClassOf obo:HP_0001279 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#simple_visual_pattern> a rdfs:Class ;
  rdfs:label "simple visual pattern" ;
  rdfs:seeAlso <https://www.mayoclinicproceedings.org/article/S0025-6196(11)63178-9/fulltext> ;
  rdfs:subClassOf <https://bio.scai.fraunhofer.de/ontology/epilepsy#positive_visual_hallucination> .

obo:GO_0032501 a rdfs:Class ;
  rdfs:label "multicellular organismal process" ;
  rdfs:comment "Any biological process, occurring at the level of a multicellular organism, pertinent to its function." ;
  rdfs:subClassOf obo:GO_0008150 .

obo:NCIT_C84834 a rdfs:Class ;
  rdfs:label "Malformations of Cortical Development" ;
  rdfs:comment "A group of neural cortical developmental malformations of diverse genetic causes. Clinical manifestations include epilepsy and developmental delays." ;
  rdfs:subClassOf <https://bio.scai.fraunhofer.de/ontology/epilepsy#structural_etiology> .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#self_limited_seizure> a rdfs:Class ;
  rdfs:label "self limited seizure" ;
  rdfs:subClassOf obo:SYMP_0000124 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#non-deterministic_model> a rdfs:Class ;
  rdfs:label "non-deterministic model" ;
  rdfs:subClassOf <https://bio.scai.fraunhofer.de/ontology/epilepsy#in_silico_model> .

obo:UBERON_0001945 a rdfs:Class ;
  rdfs:label "superior colliculus" ;
  rdfs:comment "Part of the midbrain tecturm consisting of paired bodies that sit caudal to the thalamus and surround the pineal gland in the mesencephalon of vertebrate brains. It comprises the rostral aspect of the midbrain, posterior to the periaqueductal gray and adjacent superior the inferior colliculus. The inferior and superior colliculi are known collectively as the corpora quadrigemina (Latin, quadruplet bodies). It consists of several identified cellular layers and also comprises the brachium of the superior colliculus and commissure of supeior colliculus from Wikipedia.org and Neuronames (MM)." ;
  rdfs:subClassOf obo:UBERON_0002616 , obo:UBERON_0006794 .

obo:NBO_0000419 a rdfs:Class ;
  rdfs:label "sleeping behavior phenotype" ;
  rdfs:comment "\"Observable characteristic of behavior related to the readily reversible state of reduced awareness and metabolic activity that occurs periodically in many animals.\" [NBO:GVG]" ;
  rdfs:subClassOf obo:NBO_0000473 .

obo:DOID_8857 a rdfs:Class ;
  rdfs:label "lupus erythematosus" ;
  rdfs:comment "An autoimmune hypersensitivity disease that is characterized by a constellation of findings that include elevated antibodies to nuclear antigens, antiphospholipids, low complement levels, ulcers, non-scarring alopecia, renal or neurologic damage, and low white blood cell and platelet counts, has_symptom rashes, fatigue, arthritis, hair loss, seizures, and symptoms related to affected organs, and has_material_basis_in autoimmune disorder." ;
  rdfs:subClassOf obo:DOID_417 .

<https://bio.scai.fraunhofer.de/ontology/0000411> a rdfs:Class ;
  rdfs:label "etiology TM_BIN" ;
  rdfs:comment "The 'etiology TM_BIN' concept enables a compilation of diverse concepts that are related to the etiology of Epilepsy via the Axiome 'isEtiologyFor some epilepsy'.  Thus enables the adaptation of the ontology for text mining purposes for Epilepsy related information retrieval and information extraction." .

obo:HP_0030826 a rdfs:Class ;
  rdfs:label "Eyelid fasciculation" ;
  rdfs:comment "Tiny, repetitive muscle contractions in the eyelids, causing the appearance of twitching." ;
  rdfs:subClassOf obo:HP_0031785 .

obo:NCIT_C18020 a rdfs:Class ;
  rdfs:label "Diagnostic Procedure" ;
  rdfs:comment "Any procedure or test to diagnose a disease or disorder." ;
  rdfs:subClassOf obo:OAE_0000002 .

obo:HP_0002167 a rdfs:Class ;
  rdfs:label "Neurological speech impairment" ;
  rdfs:subClassOf obo:HP_0011446 .

obo:DOID_0050628 a rdfs:Class ;
  rdfs:label "advanced sleep phase syndrome" ;
  rdfs:comment "A sleep disorder that involves an altered circadian rhythm resulting in falling asleep in early evening and awaking very early in the morning." ;
  rdfs:seeAlso <http://www.case.edu/EpSO.owl#AdvancedSleepPhaseSyndrome> ;
  rdfs:subClassOf obo:DOID_0050736 .

obo:HP_0001311 a rdfs:Class ;
  rdfs:label "Abnormal nervous system electrophysiology" ;
  rdfs:comment "An abnormality of the function of the electrical signals with which nerve cells communicate with each other or with muscles as measured by electrophysiological investigations." ;
  rdfs:seeAlso <http://www.case.edu/EpSO.owl#ElectrophysiologicalData> ;
  rdfs:subClassOf obo:HP_0012638 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#self_gratification> a rdfs:Class ;
  rdfs:label "self gratification" ;
  rdfs:subClassOf obo:NCIT_C35470 .

obo:MMO_0000435 a rdfs:Class ;
  rdfs:label "urine potassium analysis" ;
  rdfs:comment "A method which assesses the amount, proportions or properties of potassium in urine, the fluid waste product excreted by the kidneys. Potassium, the chemical element with atomic number 19 that in its ionic form has lost one electron, forming a cation with a charge of +1, is the chief cation of intracellular fluid." ;
  rdfs:subClassOf obo:MMO_0000433 .

obo:HP_0011354 a rdfs:Class ;
  rdfs:label "Generalized abnormality of skin" ;
  rdfs:comment "An abnormality of the skin that is not localized to any one particular region." ;
  rdfs:subClassOf obo:HP_0011121 .

obo:UBERON_0013560 a rdfs:Class ;
  rdfs:label "Brodmann (1909) area 32" ;
  rdfs:comment "The Brodmann area 32, also known in the human brain as the dorsal anterior cingulate area 32, refers to a subdivision of the cytoarchitecturally defined cingulate region of cerebral cortex. In the human it forms an outer arc around the anterior cingulate gyrus. The cingulate sulcus defines approximately its inner boundary and the superior rostral sulcus (H) its ventral boundary; rostrally it extends almost to the margin of the frontal lobe. Cytoarchitecturally it is bounded internally by the ventral anterior cingulate area 24, externally by medial margins of the agranular frontal area 6, intermediate frontal area 8, granular frontal area 9, frontopolar area 10, and prefrontal area 11-1909. (Brodmann19-09). Dorsal region of anterior cingulate gyrus is associated with rational thought processes, most notably active during the Stroop task." ;
  rdfs:subClassOf obo:UBERON_0013529 .

obo:HP_0011165 a rdfs:Class ;
  rdfs:label "Visual auras" ;
  rdfs:comment "Auras with sensation of flashing or flickering lights, spots, simple patterns, scotomata, or amaurosis." ;
  rdfs:seeAlso <https://academic.oup.com/brain/article/123/2/244/346024> , <http://www.case.edu/EpSO.owl#VisualAura> ;
  rdfs:subClassOf obo:HP_0011157 .

obo:MONDO_0020070 a rdfs:Class ;
  rdfs:label "neonatal epilepsy syndrome" ;
  rdfs:subClassOf obo:DOID_225 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#focal_cognitive_seizure_with_forced_thinking> a rdfs:Class ;
  rdfs:label "focal cognitive seizure with forced thinking" ;
  rdfs:seeAlso <https://www.epilepsy.com/connect/forums/living-epilepsy-adults/forced-thinking> ;
  rdfs:subClassOf <https://bio.scai.fraunhofer.de/ontology/epilepsy#focal_cognitive_seizure> .

obo:HP_0011186 a rdfs:Class ;
  rdfs:label "Focal epileptiform discharges with limited propagation to contralateral hemisphere" ;
  rdfs:comment "Focal epileptiform discharges with spreading to contralateral hemisphere but without secondary generalization." ;
  rdfs:subClassOf obo:HP_0011185 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#beta_coma> a rdfs:Class ;
  rdfs:label "beta coma" ;
  rdfs:seeAlso <http://www.case.edu/EpSO.owl#BetaComa> ;
  rdfs:subClassOf <https://bio.scai.fraunhofer.de/ontology/epilepsy#special_pattern> .

obo:DOID_14566 a rdfs:Class ;
  rdfs:label "disease of cellular proliferation" ;
  rdfs:comment "A disease that is characterized by abnormally rapid cell division." ;
  rdfs:subClassOf obo:DOID_4 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#parieto_occipital_epilepsy> a rdfs:Class ;
  rdfs:label "parieto occipital epilepsy" ;
  rdfs:seeAlso <http://www.case.edu/EpSO.owl#ParietoOccipitalEpilepsy> ;
  rdfs:subClassOf obo:DOID_1826 .

obo:HP_0010820 a rdfs:Class ;
  rdfs:label "Dacrystic seizures" ;
  rdfs:comment "A type of seizure characterized by crying or an outburst of crying as a major feature." ;
  rdfs:seeAlso <https://www.epilepsy.com/learn/types-seizures/gelastic-and-dacrystic-seizures> ;
  rdfs:subClassOf obo:HP_0025613 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#tapping> a rdfs:Class ;
  rdfs:label "tapping" ;
  rdfs:subClassOf obo:SYMP_0000891 .

obo:PW_0000060 a rdfs:Class ;
  rdfs:label "long term potentiation" ;
  rdfs:comment "Long-term potentiation (LTP) is a strengthening of the synapse that can last from hours to days and months.  It is thought to underlie information storage and constitute the cellular basis of learning and memory.  LTP engages numerous cascades of events on either side of the synapse and is accompanied by changes in gene expression." ;
  rdfs:subClassOf obo:PW_0000001 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#focal_bilateral_motor_seizure> a rdfs:Class ;
  rdfs:label "focal bilateral motor seizure" ;
  rdfs:subClassOf obo:HP_0011153 .

obo:MP_0003953 a rdfs:Class ;
  rdfs:label "abnormal hormone level" ;
  rdfs:comment "aberrant tissue or circulating concentration of any substance, usually a peptide or steroid, that has a specific metabolic regulatory effect on the activity or behavior of cells expressing a receptor for the hormone" ;
  rdfs:subClassOf obo:OGMS_0000037 .

obo:DOID_0060040 a rdfs:Class ;
  rdfs:label "pervasive developmental disorder" ;
  rdfs:comment "A developmental disorder of mental health that refers to a group of five disorders characterized by impairments in socialization and communication, as well as restricted interests and repetitive behaviors." ;
  rdfs:subClassOf obo:DOID_0060037 .

obo:MFOEM_000056 a rdfs:Class ;
  rdfs:label "sadness" ;
  rdfs:comment "A negative emotion felt when an event is appraised as unpleasant, obstructive to one's goals and concerns, and one feels unable to cope with it or modify it. [Source: OCEAS]" ;
  rdfs:seeAlso <https://www.epilepsy.org.uk/info/depression> ;
  rdfs:subClassOf obo:MFOEM_000001 .

obo:MFOEM_000026 a rdfs:Class ;
  rdfs:label "fear" ;
  rdfs:comment "An activated, aversive emotion that motivates attempts to cope with events that provide threats to the survival or well-being of organisms. Characterised by feelings of threat and impending doom, and by an urge to get out of the situation. [Source: OCEAS]" ;
  rdfs:subClassOf obo:MFOEM_000001 .

obo:OBI_0000968 a rdfs:Class ;
  rdfs:label "device" ;
  rdfs:comment "A material entity that is designed to perform a function in a scientific investigation, but is not a reagent." ;
  rdfs:subClassOf obo:OBI_0000047 .

obo:HP_0000478 a rdfs:Class ;
  rdfs:label "Abnormality of the eye" ;
  rdfs:comment "Any abnormality of the eye, including location, spacing, and intraocular abnormalities." ;
  rdfs:subClassOf obo:HP_0000118 .

obo:ERO_0000598 a rdfs:Class ;
  rdfs:label "educational intervention" ;
  rdfs:comment "An intervention which involves education, training programs, and courses in various fields and disciplines, and for training groups of persons." ;
  rdfs:subClassOf obo:ERO_0000347 .

<https://bio.scai.fraunhofer.de/ontology/0000404> a rdfs:Class ;
  rdfs:label "sign and symptom TM_BIN" ;
  rdfs:comment "The 'sign and symptom TM_BIN' concept enables a compilation of diverse concepts that are related to signs and symptoms in Epilepsy via the Axiome 'isSignAndSymptomsFor some epilepsy'.  Thus enables the adaptation of the ontology for text mining purposes for Epilepsy related information retrieval and information extraction." .

obo:HP_0001999 a rdfs:Class ;
  rdfs:label "Abnormal facial shape" ;
  rdfs:comment "An abnormal morphology (form) of the face or its components." ;
  rdfs:seeAlso <https://www.mendelian.co/symptoms/abnormal-facial-shape-and-polymicrogyria> ;
  rdfs:subClassOf obo:HP_0000271 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#negative_visual_illusion> a rdfs:Class ;
  rdfs:label "negative visual illusion" ;
  rdfs:subClassOf obo:HP_0000504 .

obo:SYMP_0000188 a rdfs:Class ;
  rdfs:label "abdominal discomfort" ;
  rdfs:subClassOf obo:SYMP_0000461 .

<https://bio.scai.fraunhofer.de/ontology/0000509> a rdfs:Class ;
  rdfs:label "global connectivity measure" ;
  rdfs:subClassOf obo:IAO_0000027 .

obo:SYMP_0000450 a rdfs:Class ;
  rdfs:label "shock" ;
  rdfs:comment "A cardiovascular system symptom that is characterized as a state of profound depression of the vital processes of the body that is characterized by pallor, rapid but weak pulse, rapid and shallow respiration, reduced total blood volume, and low blood pressure and that is caused usually by severe especially crushing injuries, hemorrhage, burns, or major surgery." ;
  rdfs:subClassOf obo:SYMP_0000528 .

obo:HP_0030049 a rdfs:Class ;
  rdfs:label "Brain abscess" ;
  rdfs:comment "A collection of pus, immune cells, and other material in the brain." ;
  rdfs:seeAlso <http://www.case.edu/EpSO.owl#CerebralAbcess> ;
  rdfs:subClassOf obo:HP_0011450 , obo:HP_0025615 .

obo:MONDO_0042983 a rdfs:Class ;
  rdfs:label "neurocutaneous syndrome" ;
  rdfs:comment "A group of disorders characterized by ectodermal-based malformations and neoplastic growths in the skin, nervous system, and other organs." ;
  rdfs:subClassOf obo:DOID_863 .

obo:HP_0025613 a rdfs:Class ;
  rdfs:label "Focal emotional seizure" ;
  rdfs:comment "A type of focal-onset seizure characterized by alterations in mood or emotion, or the appearance of altered emotion without the subjective emotion, at seizure onset. These emotional seizures may occur with or without objective clinical signs of a seizure evident to the observer." ;
  rdfs:subClassOf <https://bio.scai.fraunhofer.de/ontology/epilepsy#focal_non-motor_onset_seizure> .

obo:NBO_0000388 a rdfs:Class ;
  rdfs:label "involuntary movement behavior" ;
  rdfs:comment "\"Behavior related to movements that occur independent of planning.\" [NBO:GVG]" ;
  rdfs:subClassOf obo:NBO_0000001 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#occipital_lobe_epilepsy> a rdfs:Class ;
  rdfs:label "occipital lobe epilepsy" ;
  rdfs:seeAlso <http://www.case.edu/EpSO.owl#LateralFrontalEpilepsy> ;
  rdfs:subClassOf obo:DOID_1826 .

obo:HP_0012006 a rdfs:Class ;
  rdfs:label "Jamais vu" ;
  rdfs:comment "A subjective feeling that an experience which has occurred before is being experienced for the first time." ;
  rdfs:subClassOf obo:HP_0012004 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#organophosphates_model> a rdfs:Class ;
  rdfs:label "organophosphates model" ;
  rdfs:subClassOf obo:NCIT_C19021 .

obo:HP_0030178 a rdfs:Class ;
  rdfs:label "Abnormality of central nervous system electrophysiology" ;
  rdfs:subClassOf obo:HP_0001311 .

obo:NCIT_C50558 a rdfs:Class ;
  rdfs:label "Fall" ;
  rdfs:comment "A sudden movement downward, usually resulting in injury." ;
  rdfs:seeAlso <https://www.epilepsy.com/learn/age-groups/seniors-and-epilepsy/falls-during-seizures> ;
  rdfs:subClassOf obo:NCIT_C25499 .

obo:SYMP_0000514 a rdfs:Class ;
  rdfs:label "respiratory system and chest symptom" ;
  rdfs:subClassOf obo:SYMP_0000462 .

obo:HP_0031814 a rdfs:Class ;
  rdfs:label "Palilalia" ;
  rdfs:comment "Repetition of one's own words or phrases." ;
  rdfs:subClassOf obo:HP_0002167 .

obo:NBO_0000568 a rdfs:Class ;
  rdfs:label "kinesthetic behavior phenotype" ;
  rdfs:comment "\"Observable characteristic of behavior related to the movement of the body's muscles, tendons, and joints.\" [NBO:GVG]" ;
  rdfs:subClassOf obo:NBO_0000243 .

obo:PW_0000023 a rdfs:Class ;
  rdfs:label "immune response pathway" ;
  rdfs:comment "The Immune response pathways mediate the defense of host cells against infection and injury. The first line of defense is provided by the phylogenetically older innate immune response. The later, more versatile response is provided by the pathways of adaptive immunity: the B cell mediated humoral and the T cell mediated cellular or cell-mediated responses." ;
  rdfs:subClassOf obo:PW_0000001 .

obo:MONDO_0019040 a rdfs:Class ;
  rdfs:label "chromosomal anomaly" ;
  rdfs:comment "Clinical conditions caused by an abnormal chromosome constitution in which there is extra or missing chromosome material (either a whole chromosome or a chromosome segment). (from Thompson et al., Genetics in Medicine, 5th ed, p429)" ;
  rdfs:seeAlso <https://www.epilepsydiagnosis.org/aetiology/chromosomal-abnormalities-overview.html> , <http://www.case.edu/EpSO.owl#ChromosomalAbnormality> ;
  rdfs:subClassOf <https://bio.scai.fraunhofer.de/ontology/epilepsy#genetic_etiology> .

obo:MONDO_0018214 a rdfs:Class ;
  rdfs:label "generalized epilepsy with febrile seizures plus" ;
  rdfs:comment "Generalized epilepsy with febrile seizures plus (GEFS+) is a familial epilepsy syndrome in which family members display a seizure disorder from the GEFS+ spectrum which ranges from simple febrile seizures (FS) to the more severe phenotype of myoclonic-astatic epilepsy (MAE) or Dravet syndrome (DS) (see these terms)." ;
  rdfs:seeAlso <http://www.case.edu/EpSO.owl#GeneralizedEpilepsyWithFebrileSeizuresPlus> ;
  rdfs:subClassOf obo:DOID_1826 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#kainic_acid_model> a rdfs:Class ;
  rdfs:label "kainic acid model" ;
  rdfs:subClassOf <https://bio.scai.fraunhofer.de/ontology/epilepsy#convulsant_drug_model> .

obo:GO_0043084 a rdfs:Class ;
  rdfs:label "penile erection" ;
  rdfs:comment "The hardening, enlarging and rising of the penis which often occurs in the sexually aroused male and enables sexual intercourse. Achieved by increased inflow of blood into the vessels of erectile tissue, and decreased outflow." ;
  rdfs:subClassOf obo:GO_0048609 .

obo:HP_0000504 a rdfs:Class ;
  rdfs:label "Abnormality of vision" ;
  rdfs:comment "Abnormality of eyesight (visual perception)." ;
  rdfs:subClassOf obo:HP_0012373 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#parasitic_cyst> a rdfs:Class ;
  rdfs:label "parasitic cyst" ;
  rdfs:seeAlso <http://www.case.edu/EpSO.owl#ParasiticCysts> ;
  rdfs:subClassOf obo:IDO_0000586 .

obo:HP_0500165 a rdfs:Class ;
  rdfs:label "Abnormal blood oxygen level" ;
  rdfs:comment "An abnormality of the partial pressure of oxygen in the arterial blood." ;
  rdfs:subClassOf obo:HP_0012415 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#C57BL/10Bg_mouse> a rdfs:Class ;
  rdfs:label "C57BL/10Bg sps/sps mouse" ;
  rdfs:subClassOf <https://bio.scai.fraunhofer.de/ontology/epilepsy#absence_seizure_model> .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#gene_panel_sequencing> a rdfs:Class ;
  rdfs:label "gene panel sequencing" ;
  rdfs:subClassOf obo:ERO_0001286 .

obo:NCIT_C86580 a rdfs:Class ;
  rdfs:label "Pleasure" ;
  rdfs:comment "An emotion associated with feeling good." ;
  rdfs:subClassOf obo:MF_0000020 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#benign_neonatal_sleep_myoclonus> a rdfs:Class ;
  rdfs:label "benign neonatal sleep myoclonus" ;
  rdfs:subClassOf obo:DOID_535 .

obo:CMO_0001303 a rdfs:Class ;
  rdfs:label "blood lactate level" ;
  rdfs:subClassOf obo:CMO_0000023 .

obo:MONDO_0015917 a rdfs:Class ;
  rdfs:label "malignant glioma" ;
  rdfs:comment "A grade III or grade IV glioma arising from the central nervous system. This category includes glioblastoma, anaplastic astrocytoma, anaplastic ependymoma, anaplastic oligodendroglioma, and anaplastic oligoastrocytoma." ;
  rdfs:subClassOf obo:MONDO_0021042 .

obo:DOID_302 a rdfs:Class ;
  rdfs:label "substance abuse" ;
  rdfs:comment "A substance-related disorder that involves a maladaptive pattern of substance use leading to significant impairment in functioning." ;
  rdfs:seeAlso <https://www.epilepsy.com/learn/triggers-seizures/drug-abuse> , <http://www.case.edu/EpSO.owl#SubstanceAbuse> ;
  rdfs:subClassOf obo:DOID_303 .

obo:RS_0000480 a rdfs:Class ;
  rdfs:label "GAERS" ;
  rdfs:subClassOf obo:RS_0000765 .

obo:OAE_0000001 a rdfs:Class ;
  rdfs:label "adverse event" ;
  rdfs:comment "a pathological bodily process that occurs after a medical intervention. An adverse event is likely caused by the medical intervention; however, such a causal association is not required to be an adverse event." ;
  rdfs:subClassOf obo:OGMS_0000061 .

obo:HP_0002521 a rdfs:Class ;
  rdfs:label "Hypsarrhythmia" ;
  rdfs:comment "Hypsarrhythmia is abnormal interictal high amplitude waves and a background of irregular spikes. There is continuous (during wakefulness), high-amplitude (>200 Hz), generalized polymorphic slowing with no organized background and multifocal spikes demonstrated by electroencephalography (EEG)." ;
  rdfs:seeAlso <http://www.case.edu/EpSO.owl#Hypsarrhythmia> ;
  rdfs:subClassOf obo:HP_0011198 .

obo:UBERON_0001893 a rdfs:Class ;
  rdfs:label "telencephalon" ;
  rdfs:comment "Part of the forebrain consisting of paired olfactory bulbs and cerebral hemispheres." ;
  rdfs:subClassOf obo:UBERON_0002616 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#reading_epilepsy> a rdfs:Class ;
  rdfs:label "reading epilepsy" ;
  rdfs:seeAlso <http://www.case.edu/EpSO.owl#PrimaryReadingEpilepsy> ;
  rdfs:subClassOf obo:DOID_2548 .

obo:NCIT_C19146 a rdfs:Class ;
  rdfs:label "In Vitro Model" ;
  rdfs:subClassOf obo:NCIT_C17456 .

obo:DOID_7148 a rdfs:Class ;
  rdfs:label "rheumatoid arthritis" ;
  rdfs:comment "An arthritis that is an autoimmune disease which attacks healthy cells and tissue located_in joint." ;
  rdfs:seeAlso <https://www.healio.com/rheumatology/rheumatoid-arthritis/news/online/%7Bc65ca682-7bc8-4bae-8c69-45b38526cf5e%7D/patients-with-ra-may-be-at-higher-risk-for-epilepsy> ;
  rdfs:subClassOf obo:DOID_848 .

obo:HP_0002579 a rdfs:Class ;
  rdfs:label "Gastrointestinal dysmotility" ;
  rdfs:comment "Abnormal intestinal contractions, such as spasms and intestinal paralysis, related to the loss of the ability of the gut to coordinate muscular activity because of endogenous or exogenous causes." ;
  rdfs:subClassOf obo:HP_0030895 .

obo:DOID_5340 a rdfs:Class ;
  rdfs:label "anterograde amnesia" ;
  rdfs:comment "An amnestic disorder that involves the impaired or lost ability to memorize new things." ;
  rdfs:subClassOf obo:DOID_10914 .

obo:NBO_0000056 a rdfs:Class ;
  rdfs:label "walking behavior" ;
  rdfs:comment "The act of locomoting on limbs with body off the ground such that at least one limb is always touching the ground [NBO:AC]" ;
  rdfs:subClassOf obo:NBO_0000359 .

obo:DOID_1094 a rdfs:Class ;
  rdfs:label "attention deficit hyperactivity disorder" ;
  rdfs:comment "A specific developmental disorder that is characterized by co-existence of attentional problems and hyperactivity, with each behavior occurring infrequently alone and symptoms starting before seven years of age." ;
  rdfs:subClassOf obo:DOID_0060038 .

obo:DOID_3069 a rdfs:Class ;
  rdfs:label "astrocytoma" ;
  rdfs:comment "A malignant glioma that is has_material_basis_in astrocyte cells, a type of star-shaped glial cell, located in the brain and spinal cord." ;
  rdfs:subClassOf obo:MONDO_0015917 .

obo:UBERON_0019264 a rdfs:Class ;
  rdfs:label "gray matter of forebrain" ;
  rdfs:subClassOf obo:UBERON_0003528 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#blank_stare> a rdfs:Class ;
  rdfs:label "blank stare" ;
  rdfs:subClassOf obo:SYMP_0000480 .

obo:NCIT_C19332 a rdfs:Class ;
  rdfs:label "Personal Attribute" ;
  rdfs:comment "The distinguishing qualities or prominent aspects of an individual person." ;
  rdfs:subClassOf obo:IAO_0000030 .

obo:PW_0000325 a rdfs:Class ;
  rdfs:label "protein degradation pathway" ;
  rdfs:comment "Those pathways involved in the degradation of proteins." ;
  rdfs:subClassOf obo:PW_0000001 .

obo:NBO_0000017 a rdfs:Class ;
  rdfs:label "biting" ;
  rdfs:comment "The act of seizing with teeth or jaws an object or organism so as to grip or break the surface covering [NBO:AC]" ;
  rdfs:subClassOf obo:NBO_0000747 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#GABA-B_receptor_antibody> a rdfs:Class ;
  rdfs:label "GABA-B receptor antibody" ;
  rdfs:subClassOf obo:MONDO_0100029 .

obo:HP_0011160 a rdfs:Class ;
  rdfs:label "Focal sensory gustatory seizure" ;
  rdfs:comment "Auras with taste sensations including acidic, bitter, salty , sweet or metallic tastes." ;
  rdfs:subClassOf obo:HP_0011157 .

obo:DOID_77 a rdfs:Class ;
  rdfs:label "gastrointestinal system disease" ;
  rdfs:comment "A disease of anatomical entity that is located_in the gastrointestinal tract." ;
  rdfs:subClassOf obo:DOID_7 .

obo:MONDO_0100022 a rdfs:Class ;
  rdfs:label "neonatal/infantile epilepsy syndrome" ;
  rdfs:comment "An epilepsy sydrome that has an onset during the neonatal or infantile stage of life." ;
  rdfs:subClassOf obo:MONDO_0015650 .

obo:HP_0032046 a rdfs:Class ;
  rdfs:label "Focal cortical dysplasia" ;
  rdfs:comment "A type of malformation of cortical development that primarily affects areas of neocortex. It can be identified on conventional magnetic resonance imaging as focal cortical thickening, abnormal gyration, and blurring between gray and white matter, often associated with clusters of heterotopic neurons." ;
  rdfs:seeAlso <http://www.case.edu/EpSO.owl#FocalCorticalDysplasia> ;
  rdfs:subClassOf obo:NCIT_C84834 .

obo:NCIT_C18772 a rdfs:Class ;
  rdfs:label "Personal Medical History" ;
  rdfs:comment "A record of a patient's background regarding health and the occurrence of disease events of the individual. In addition, personal medical history may be a variable in epidemiologic studies." ;
  rdfs:subClassOf obo:NCIT_C19332 .

obo:OMIT_0005690 a rdfs:Class ;
  rdfs:label "Eating" ;
  rdfs:seeAlso <https://n.neurology.org/content/86/16_Supplement/P6.367> ;
  rdfs:subClassOf obo:GO_0007610 .

obo:MONDO_0015642 a rdfs:Class ;
  rdfs:label "benign partial infantile seizures" ;
  rdfs:subClassOf obo:MONDO_0020071 .

obo:BFO_0000038 a rdfs:Class ;
  rdfs:label "one-dimensional temporal region" ;
  rdfs:subClassOf obo:BFO_0000008 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#benign_electroencephalographic_pattern> a rdfs:Class ;
  rdfs:label "benign electroencephalographic pattern" ;
  rdfs:seeAlso <http://www.case.edu/EpSO.owl#BenignEEGPattern> ;
  rdfs:subClassOf obo:MP_0004994 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#gait_induced_seizure> a rdfs:Class ;
  rdfs:label "gait induced seizure" ;
  rdfs:subClassOf obo:SYMP_0000124 .

obo:CMO_0000294 a rdfs:Class ;
  rdfs:label "pulse" ;
  rdfs:subClassOf obo:CMO_0000001 .

obo:DOID_11038 a rdfs:Class ;
  rdfs:label "depersonalization disorder" ;
  rdfs:comment "A dissociative disorder in which the sufferer is affected by persistent or recurrent feelings of depersonalization and/or derealization." ;
  rdfs:subClassOf obo:DOID_150 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#GAD65_antibody> a rdfs:Class ;
  rdfs:label "GAD65 antibody" ;
  rdfs:subClassOf obo:MONDO_0100029 .

obo:NBO_0000009 a rdfs:Class ;
  rdfs:label "locomotory behavior phenotype" ;
  rdfs:comment "\"Observable characteristic of behavior associated with the specific movement from place to place of an organism.\" [NBO:GVG]" ;
  rdfs:subClassOf obo:NBO_0000644 .

obo:HP_0032050 a rdfs:Class ;
  rdfs:label "Focal cortical dysplasia type Ic" ;
  rdfs:comment "A subtype of focal cortical dysplasia type I that is characterized by abnormal radial and tangential cortical lamination." ;
  rdfs:seeAlso <http://www.case.edu/EpSO.owl#FocalCorticalDysplasiaTypeIC> ;
  rdfs:subClassOf obo:HP_0032047 .

obo:UBERON_0006092 a rdfs:Class ;
  rdfs:label "cuneus cortex" ;
  rdfs:comment "Component of the occipital lobe. The rostral boundary was the first coronal slice above the calcarine sulcus where the cuneus cortex becomes visible whereas the caudal boundary was the last slice where the calcarine sulcus was visualized. The medial boundary was the most medial portion of the occipital and parietal cortices. The superio-lateral boundary was the parieto-occipital fissure whereas the inferolateral boundary was the pericalcarine cortex (Christine Fennema-Notestine)." ;
  rdfs:subClassOf obo:UBERON_0014640 .

obo:UBERON_0001876 a rdfs:Class ;
  rdfs:label "amygdala" ;
  rdfs:comment "Subcortical brain region lying anterior to the hippocampal formation in the temporal lobe and anterior to the temporal horn of the lateral ventricle in some species. It is usually subdivided into several groups. Functionally, it is not considered a unitary structure (MM)." ;
  rdfs:seeAlso <http://www.case.edu/EpSO.owl#Amygdala> ;
  rdfs:subClassOf obo:UBERON_0002420 , obo:UBERON_0005401 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#focal_behaviour_arrest_seizure> a rdfs:Class ;
  rdfs:label "focal behaviour arrest seizure" ;
  rdfs:subClassOf <https://bio.scai.fraunhofer.de/ontology/epilepsy#focal_non-motor_onset_seizure> .

obo:HP_0010677 a rdfs:Class ;
  rdfs:label "Enuresis nocturna" ;
  rdfs:comment "Enuresis occurring during sleeping hours." ;
  rdfs:seeAlso <http://www.case.edu/EpSO.owl#Bedwetting> ;
  rdfs:subClassOf obo:HP_0000805 .

obo:DOID_0111537 a rdfs:Class ;
  rdfs:label "paroxysmal extreme pain disorder" ;
  rdfs:comment "An autonomic nervous system disease characterized by onset in the neonatal period or infancy of paroxysms of rectal, ocular, or submandibular pain with flushing that has_material_basis_in heterozygous mutation in SCN9A on chromosome 2q24.3." ;
  rdfs:subClassOf obo:NCIT_C69023 .

obo:CMO_0000035 a rdfs:Class ;
  rdfs:label "blood measurement" ;
  rdfs:seeAlso <https://www.webmd.com/epilepsy/guide/epilepsy-blood-test> ;
  rdfs:subClassOf obo:CMO_0000000 .

obo:MP_0003969 a rdfs:Class ;
  rdfs:label "abnormal luteinizing hormone level" ;
  rdfs:comment "aberrant levels in the bloodstream of LH, the hormone that regulates steroid production by the interstitial cells of the testis and the ovary" ;
  rdfs:subClassOf obo:MP_0003965 .

obo:DOID_0050425 a rdfs:Class ;
  rdfs:label "restless legs syndrome" ;
  rdfs:comment "A central nervous system disease characterized by throbbing, pulling creeping or other unpleasant sensations in the legs and the irresistible urge to move them." ;
  rdfs:seeAlso <http://www.case.edu/EpSO.owl#RestlessLegSyndrome> , <https://www.epilepsy.com/learn/professionals/co-existing-disorders/sleep-disorders/periodic-limb-movements-and-restless-legs> ;
  rdfs:subClassOf obo:DOID_331 .

obo:DOID_374 a rdfs:Class ;
  rdfs:label "nutrition disease" ;
  rdfs:comment "An acquired metabolic disease that is characterized by an insufficient intake of food or of certain nutrients, by an inability of the body to absorb and use nutrients, or by overconsumption of certain foods." ;
  rdfs:subClassOf obo:DOID_0060158 .

obo:DOID_526 a rdfs:Class ;
  rdfs:label "human immunodeficiency virus infectious disease" ;
  rdfs:comment "A viral infectious disease that results in destruction of immune system, leading to life-threatening opportunistic infections and cancers, has_material_basis_in Human immunodeficiency virus 1 or has_material_basis_in Human immunodeficiency virus 2, which are transmitted by sexual contact, transmitted by transfer of blood, semen, vaginal fluid, pre-ejaculate, or breast milk, transmitted by congenital method, and transmitted by contaminated needles. The virus infects helper T cells (CD4+ T cells) which are directly or indirectly destroyed, macrophages, and dendritic cells. The infection has symptom diarrhea, has symptom fatigue, has symptom fever, has symptom vaginal yeast infection, has symptom headache, has symptom mouth sores, has symptom muscle aches, has symptom sore throat, and has symptom swollen lymph glands." ;
  rdfs:subClassOf <https://bio.scai.fraunhofer.de/ontology/epilepsy#infectious_etiology> .

obo:DOID_14503 a rdfs:Class ;
  rdfs:label "neuronal ceroid lipofuscinosis" ;
  rdfs:comment """Xref MGI.
OMIM mapping submitted by NeuroDevNet. [LS].""" ;
  rdfs:subClassOf obo:DOID_9455 .

obo:IDO_0000586 a rdfs:Class ;
  rdfs:label "infection" ;
  rdfs:comment "A part of an extended organism that itself has as part a population of one or more infectious agents and that (1) exists as a result of processes initiated by members of the infectious agent population and is (2) clinically abnormal in virtue of the presence of this infectious agent population, or (3) has a disposition to bring clinical abnormality to immunocompetent organisms of the same Species as the host (the organism corresponding to the extended organism) through transmission of a member or offspring of a member of the infectious agent population." ;
  rdfs:seeAlso <http://www.case.edu/EpSO.owl#Infection> ;
  rdfs:subClassOf obo:BFO_0000040 .

obo:NCIT_C157609 a rdfs:Class ;
  rdfs:label "Complication due to Medical/Surgical Care" ;
  rdfs:subClassOf obo:NCIT_C2959 .

obo:DOID_26 a rdfs:Class ;
  rdfs:label "pancreas disease" ;
  rdfs:comment "An endocrine system disease that is located_in the pancreas." ;
  rdfs:subClassOf obo:DOID_28 .

obo:OMIT_0002976 a rdfs:Class ;
  rdfs:label "Beta Rhythm" ;
  rdfs:seeAlso <http://www.case.edu/EpSO.owl#BetaActivity> ;
  rdfs:subClassOf obo:OMIT_0027154 .

obo:MONDO_0015346 a rdfs:Class ;
  rdfs:label "Jeavons syndrome" ;
  rdfs:comment "Jeavons syndrome is an idiopathic generalized form of reflex epilepsy characterized by childhood onset, unique seizure manifestations, striking light sensitivity, and possible occurrence of generalized tonic-clonic seizures." ;
  rdfs:subClassOf obo:MONDO_0020072 .

obo:NCIT_C15359 a rdfs:Class ;
  rdfs:label "Salvage Therapy" ;
  rdfs:comment "Performing a salvage procedure is the last resort. The clinical situation involves either ongoing life support measures, life support measures for more than 60 seconds during the prior 10 minutes, or unanticipated institution of extracorporeal circulatory support. (ACC)" ;
  rdfs:seeAlso <https://www.epilepsy.com/learn/managing-your-epilepsy/using-rescue-treatments> ;
  rdfs:subClassOf obo:OGMS_0000112 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#anatomic_neuroimaging> a rdfs:Class ;
  rdfs:label "anatomic neuroimaging" ;
  rdfs:seeAlso <https://www.apa.org/action/resources/research-in-action/scan> ;
  rdfs:subClassOf obo:OMIT_0027688 .

obo:MFOEM_000042 a rdfs:Class ;
  rdfs:label "happiness" ;
  rdfs:comment "A positive emotion which is experienced in reaction to a positive experience or event. [Source: OCEAS]" ;
  rdfs:subClassOf obo:MFOEM_000001 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#parietal_lobe_seizure> a rdfs:Class ;
  rdfs:label "parietal lobe seizure" ;
  rdfs:subClassOf <https://bio.scai.fraunhofer.de/ontology/epilepsy#seizure_based_on_lobar_localization> .

obo:OMIT_0027154 a rdfs:Class ;
  rdfs:label "Brain Waves" ;
  rdfs:subClassOf obo:OBI_0002186 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#benign_myoclonus_of_infancy_and_shuddering_attack> a rdfs:Class ;
  rdfs:label "benign myoclonus of infancy and shuddering attack" ;
  rdfs:subClassOf obo:NCIT_C69023 .

obo:HP_0000301 a rdfs:Class ;
  rdfs:label "Abnormality of facial musculature" ;
  rdfs:comment "An anomaly of a muscle that is innervated by the facial nerve (the seventh cranial nerve)." ;
  rdfs:subClassOf obo:HP_0011799 , obo:HP_0011805 .

<https://bio.scai.fraunhofer.de/ontology/0000511> a rdfs:Class ;
  rdfs:label "pre-ictal" ;
  rdfs:subClassOf obo:PATO_0001912 .

obo:SYMP_0019173 a rdfs:Class ;
  rdfs:label "meningitis" ;
  rdfs:comment "Meningitis is a nervous system symptom characterized as an inflammation of the meninges and especially of the pia mater and the arachnoid." ;
  rdfs:seeAlso <http://www.case.edu/EpSO.owl#Meningitis> ;
  rdfs:subClassOf obo:SYMP_0000480 .

obo:DOID_3211 a rdfs:Class ;
  rdfs:label "lysosomal storage disease" ;
  rdfs:comment "An inherited metabolic disorder that involve an abnormal accumulation of substances inside the lysosome resulting from defects in lysosomal function." ;
  rdfs:subClassOf obo:DOID_655 .

obo:CMO_0000094 a rdfs:Class ;
  rdfs:label "respiratory system measurement" ;
  rdfs:subClassOf obo:CMO_0000000 .

obo:UBERON_0001062 a rdfs:Class ;
  rdfs:label "anatomical entity" ;
  rdfs:comment "Biological entity that is either an individual member of a biological species or constitutes the structural organization of an individual member of a biological species." ;
  rdfs:subClassOf obo:BFO_0000040 .

obo:PATO_0001241 a rdfs:Class ;
  rdfs:label "physical object quality" ;
  rdfs:comment "A quality which inheres in a continuant." ;
  rdfs:subClassOf obo:BFO_0000019 .

obo:RS_0003717 a rdfs:Class ;
  rdfs:label "F344-Lgi1m1Kyo" ;
  rdfs:subClassOf obo:RS_0000461 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#frontal_arousal_rhythm> a rdfs:Class ;
  rdfs:label "frontal arousal rhythm" ;
  rdfs:seeAlso <http://www.case.edu/EpSO.owl#FrontalArousalRhythm> ;
  rdfs:subClassOf <https://bio.scai.fraunhofer.de/ontology/epilepsy#rhythmic_benign_variant> .

obo:DOID_1826 a rdfs:Class ;
  rdfs:label "epilepsy" ;
  rdfs:comment "A brain disease that is characterized by the occurrance of at least two unprovoked seizures resulting from a persistent epileptogenic abnormality of the brain that is able to spontaneously generate paroxysmal activity and typically manifested by sudden brief episodes of altered or diminished consciousness, involuntary movements, or convulsions." ;
  rdfs:seeAlso <http://www.case.edu/EpSO.owl#Epilepsy> ;
  rdfs:subClassOf obo:DOID_936 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#ASQ_(age_and_sex_questionnaire)> a rdfs:Class ;
  rdfs:label "age and sex questionnaire" ;
  rdfs:subClassOf obo:NCIT_C20993 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#insular_lobe_seizure> a rdfs:Class ;
  rdfs:label "insular lobe seizure" ;
  rdfs:subClassOf obo:SYMP_0000124 .

obo:MONDO_0016058 a rdfs:Class ;
  rdfs:label "paroxysmal dystonia" ;
  rdfs:subClassOf obo:DOID_480 .

obo:HP_0000009 a rdfs:Class ;
  rdfs:label "Functional abnormality of the bladder" ;
  rdfs:comment "Dysfunction of the urinary bladder." ;
  rdfs:subClassOf obo:HP_0000014 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#focal_autonomic_seizure_with_erection> a rdfs:Class ;
  rdfs:label "focal autonomic seizure with erection" ;
  rdfs:seeAlso <https://www.epilepsydiagnosis.org/seizure/autonomic-overview.html> , <http://epilepsyontario.org/about-epilepsy/types-of-seizures/simple-partial-seizures/> ;
  rdfs:subClassOf obo:HP_0011154 .

obo:DOID_399 a rdfs:Class ;
  rdfs:label "tuberculosis" ;
  rdfs:comment "A primary bacterial infectious disease that is located_in lungs, located_in lymph nodes, located_in pericardium, located_in brain, located_in pleura or located_in gastrointestinal tract, has_material_basis_in Mycobacterium tuberculosis, which is transmitted_by droplets released into the air when an infected person coughs or sneezes." ;
  rdfs:subClassOf <https://bio.scai.fraunhofer.de/ontology/epilepsy#infectious_etiology> .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#lip_smacking> a rdfs:Class ;
  rdfs:label "lip smacking" ;
  rdfs:subClassOf obo:SYMP_0019182 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#phenytion-induced_seizure> a rdfs:Class ;
  rdfs:label "phenytion-induced seizure" ;
  rdfs:subClassOf <https://bio.scai.fraunhofer.de/ontology/epilepsy#toxic_cause_of_seizure> .

obo:DOID_10934 a rdfs:Class ;
  rdfs:label "multiple personality disorder" ;
  rdfs:comment "A dissociative disorder that involves the simultaneous display of multiple distinct identities or personalities." ;
  rdfs:subClassOf obo:DOID_150 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#out_of_body_experience> a rdfs:Class ;
  rdfs:label "out of body experience" ;
  rdfs:subClassOf obo:NCIT_C35470 .

obo:UBERON_0014640 a rdfs:Class ;
  rdfs:label "occipital gyrus" ;
  rdfs:comment "A gyrus that is part of a occipital lobe." ;
  rdfs:subClassOf obo:UBERON_0000200 .

obo:NCIT_C139982 a rdfs:Class ;
  rdfs:label "Pre-operative Evaluation" ;
  rdfs:comment "An examination of an individual to determine their health status prior to a surgical procedure and their suitability for the procedure." ;
  rdfs:subClassOf obo:OBI_0000011 .

obo:NCIT_C34739 a rdfs:Class ;
  rdfs:label "Jacksonian Seizure" ;
  rdfs:comment "A partial motor seizure that begins in a single area of the body and progresses to include other areas on the same side of the body." ;
  rdfs:seeAlso <https://www.epilepsy.com/article/2013/6/do-you-know-what-jacksonian-march> ;
  rdfs:subClassOf obo:HP_0002266 .

obo:DOID_2846 a rdfs:Class ;
  rdfs:label "bruxism" ;
  rdfs:comment "A sleep disorder that involves involuntarily grinding or clenching of the teeth while sleeping." ;
  rdfs:seeAlso <http://www.case.edu/EpSO.owl#Bruxism> , <http://s3.amazonaws.com/host-article-assets/rou/588018d47f8c9d0a098b4e3a/fulltext.pdf> ;
  rdfs:subClassOf obo:SYMP_0000566 .

obo:UBERON_0000200 a rdfs:Class ;
  rdfs:label "gyrus" ;
  rdfs:comment "A ridge on the cerebral cortex. It is generally surrounded by one or more sulci ." ;
  rdfs:seeAlso <https://github.com/obophenotype/uberon/issues/573> ;
  rdfs:subClassOf obo:UBERON_0034768 .

obo:DOID_0050848 a rdfs:Class ;
  rdfs:label "obstructive sleep apnea" ;
  rdfs:comment "A sleep apnea that is characterized by repeated collapse and obstruction of the upper airway during sleep, which results in reduced airflow (hypopnea) or complete airflow cessation (apnea), oxygen desaturation, and arousals from sleep." ;
  rdfs:seeAlso <http://www.case.edu/EpSO.owl#ObstructiveSleepApnea> ;
  rdfs:subClassOf obo:DOID_0050847 .

obo:HP_0010819 a rdfs:Class ;
  rdfs:label "Atonic seizure" ;
  rdfs:comment "Atonic seizure is a type of motor seizure characterized by a sudden loss or diminution of muscle tone without apparent preceding myoclonic or tonic event lasting about 1 to 2 seconds, involving head, trunk, jaw, or limb musculature." ;
  rdfs:seeAlso <https://www.epilepsydiagnosis.org/seizure/atonic-overview.html> , <http://www.case.edu/EpSO.owl#AtonicSeizure> ;
  rdfs:subClassOf <https://bio.scai.fraunhofer.de/ontology/epilepsy#generalized_motor_onset_seizure> .

obo:OGMS_0000060 a rdfs:Class ;
  rdfs:label "bodily process" ;
  rdfs:comment "A process in which at least one bodily component of an organsim participates." ;
  rdfs:subClassOf obo:BFO_0000015 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#small_sharp_spike> a rdfs:Class ;
  rdfs:label "small sharp spike" ;
  rdfs:seeAlso <http://www.case.edu/EpSO.owl#SmallShartSpike> , <https://emedicine.medscape.com/article/1140563-overview#a1> ;
  rdfs:subClassOf <https://bio.scai.fraunhofer.de/ontology/epilepsy#epileptiform_benign_variant> .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#hyperventilation_syncope> a rdfs:Class ;
  rdfs:label "hyperventilation syncope" ;
  rdfs:subClassOf obo:HP_0001279 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#temporal_lobe_seizure> a rdfs:Class ;
  rdfs:label "temporal lobe seizure" ;
  rdfs:subClassOf <https://bio.scai.fraunhofer.de/ontology/epilepsy#seizure_based_on_lobar_localization> .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#right_frontal_encephalomalacia> a rdfs:Class ;
  rdfs:label "right frontal encephalomalacia" ;
  rdfs:seeAlso <http://www.case.edu/EpSO.owl#RightFrontalEncephalomalacia> ;
  rdfs:subClassOf obo:DOID_936 .

obo:UBERON_0011300 a rdfs:Class ;
  rdfs:label "gray matter of telencephalon" ;
  rdfs:comment "A portion of gray matter that is part of a telencephalon." ;
  rdfs:subClassOf obo:UBERON_0019264 .

obo:HP_0031884 a rdfs:Class ;
  rdfs:label "Abnormal CSF glucose level" ;
  rdfs:comment "A deviation from normal concentration of glucose content in the cerebrospinal fluid." ;
  rdfs:subClassOf obo:HP_0025454 .

obo:NBO_0000020 a rdfs:Class ;
  rdfs:label "head movement" ;
  rdfs:comment "A change in place or position of the portion of the organism containing the brain, mouth and main sense organs [NBO:SMAC]" ;
  rdfs:subClassOf obo:NBO_0000001 .

obo:SYMP_0000424 a rdfs:Class ;
  rdfs:label "claudication" ;
  rdfs:comment "A pain that is a leg pain in the calf or thigh which is caused by inadequate blood flow to the leg muscles brought on by leg exercise such as walking." ;
  rdfs:seeAlso <https://www.epilepsy.com/learn/types-seizures/atonic-seizures> ;
  rdfs:subClassOf obo:SYMP_0000099 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#focal_cognitive_seizure_with_neglect> a rdfs:Class ;
  rdfs:label "focal cognitive seizure with neglect" ;
  rdfs:subClassOf <https://bio.scai.fraunhofer.de/ontology/epilepsy#focal_cognitive_seizure> .

<https://bio.scai.fraunhofer.de/ontology/0000415> a rdfs:Class ;
  rdfs:label "treatment TM_BIN" ;
  rdfs:comment "The 'treatment TM_BIN' concept enables a compilation of diverse concepts that are related to treatment of Epilepsy via the Axiome 'isTreatmentFor some epilepsy'.  Thus enables the adaptation of the ontology for text mining purposes for Epilepsy related information retrieval and information extraction." .

obo:HP_0003236 a rdfs:Class ;
  rdfs:label "Elevated serum creatine kinase" ;
  rdfs:comment "An elevation of the level of the enzyme creatine kinase (also known as creatine phosphokinase, CPK; EC 2.7.3.2) in the blood. CPK levels can be elevated in a number of clinical disorders such as myocardial infarction, rhabdomyolysis, and muscular dystrophy." ;
  rdfs:subClassOf obo:HP_0040081 .

obo:UBERON_0008334 a rdfs:Class ;
  rdfs:label "subarachnoid sulcus" ;
  rdfs:subClassOf obo:UBERON_0013118 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#paracentral_lobule_seizure> a rdfs:Class ;
  rdfs:label "paracentral lobule seizure" ;
  rdfs:subClassOf <https://bio.scai.fraunhofer.de/ontology/epilepsy#parietal_lobe_seizure> .

obo:SYMP_0000461 a rdfs:Class ;
  rdfs:label "abdominal symptom" ;
  rdfs:subClassOf obo:SYMP_0000462 .

obo:SYMP_0019175 a rdfs:Class ;
  rdfs:label "sweaty" ;
  rdfs:comment "A skin and integumentary tissue symptom characterized as the excretion of moisture in visible quantities through the opening of the sweat glands." ;
  rdfs:subClassOf obo:SYMP_0000488 .

obo:CMO_0000046 a rdfs:Class ;
  rdfs:label "blood glucose level" ;
  rdfs:seeAlso <https://www.webmd.com/epilepsy/guide/epilepsy-blood-test> ;
  rdfs:subClassOf obo:CMO_0000023 .

obo:UBERON_0006095 a rdfs:Class ;
  rdfs:label "anterior transverse temporal area 41" ;
  rdfs:comment "A subdivision of the cytoarchitecturally defined temporal region of cerebral cortex. It occupies the anterior transverse temporal gyrus (H) in the bank of the lateral sulcus on the dorsal surface of the temporal lobe. Cytoarchitecturally it is bounded medially by the parainsular area 52 (H) and laterally by the posterior transverse temporal area 42 (H) (Brodmann-1909). Adapted from Brain Info" ;
  rdfs:subClassOf obo:UBERON_0013529 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#multifocal_epilepsy> a rdfs:Class ;
  rdfs:label "multifocal epilepsy" ;
  rdfs:seeAlso <http://www.case.edu/EpSO.owl#MultiFocalEpilepsy> ;
  rdfs:subClassOf obo:DOID_1826 .

obo:BFO_0000141 a rdfs:Class ;
  rdfs:label "immaterial entity" ;
  rdfs:subClassOf obo:BFO_0000004 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#focal_non-motor_onset_seizure> a rdfs:Class ;
  rdfs:label "focal non-motor onset seizure" ;
  rdfs:seeAlso <https://www.webmd.com/epilepsy/child-focal-seizure-symptoms#1> , <https://www.epilepsydiagnosis.org/seizure/focal-seizure-overview.html> ;
  rdfs:subClassOf <https://bio.scai.fraunhofer.de/ontology/epilepsy#focal_seizure_classification_by_onset_feature> .

obo:DOID_0111141 a rdfs:Class ;
  rdfs:label "delayed sleep phase syndrome" ;
  rdfs:comment "A sleep disorder characterized by an extreme evening preference, sleep-onset insomnia, and difficulty in awakening at the desired time." ;
  rdfs:seeAlso <http://www.case.edu/EpSO.owl#DelayedSleepPhaseSyndrome> ;
  rdfs:subClassOf obo:NBO_0000419 .

obo:HP_0032670 a rdfs:Class ;
  rdfs:label "Tonic status epilepticus" ;
  rdfs:comment "Tonic status epilepticus is a type of status epilepticus characterized by focal or bilateral limb stiffening or elevation, which may be electrographically generalized or focal." ;
  rdfs:subClassOf obo:HP_0032658 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#immediate_and_early_post_traumatic_seizure> a rdfs:Class ;
  rdfs:label "immediate and early post traumatic seizure" ;
  rdfs:subClassOf <https://bio.scai.fraunhofer.de/ontology/epilepsy#seizure_not_necessarily_requiring_a_diagnosis_of_epilepsy> .

obo:UBERON_0000122 a rdfs:Class ;
  rdfs:label "neuron projection bundle" ;
  rdfs:comment "A fasciculated bundle of neuron projections (GO:0043005), largely or completely lacking synapses." ;
  rdfs:subClassOf obo:UBERON_0005162 .

obo:CMO_0000289 a rdfs:Class ;
  rdfs:label "respiration rate" ;
  rdfs:subClassOf obo:CMO_0000114 .

obo:DOID_0060085 a rdfs:Class ;
  rdfs:label "organ system benign neoplasm" ;
  rdfs:comment "A benign neoplasm that is classified by the organ system from which it is arising from." ;
  rdfs:subClassOf obo:DOID_0060072 .

obo:UBERON_0005401 a rdfs:Class ;
  rdfs:label "cerebral hemisphere gray matter" ;
  rdfs:comment "A gray matter that is part of a cerebral hemisphere." ;
  rdfs:subClassOf obo:UBERON_0011300 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#prefrontal_epilepsy> a rdfs:Class ;
  rdfs:label "prefrontal epilepsy" ;
  rdfs:seeAlso <http://www.case.edu/EpSO.owl#PrefrontalEpilepsy> ;
  rdfs:subClassOf <https://bio.scai.fraunhofer.de/ontology/epilepsy#lateral_frontal_epilepsy> .

obo:UBERON_0000955 a rdfs:Class ;
  rdfs:label "brain" ;
  rdfs:comment "The brain is the center of the nervous system in all vertebrate, and most invertebrate, animals. Some primitive animals such as jellyfish and starfish have a decentralized nervous system without a brain, while sponges lack any nervous system at all. In vertebrates, the brain is located in the head, protected by the skull and close to the primary sensory apparatus of vision, hearing, balance, taste, and smell[WP]." ;
  rdfs:subClassOf obo:UBERON_0000062 .

obo:NCIT_C19300 a rdfs:Class ;
  rdfs:label "Non-Rodent Model" ;
  rdfs:comment "Research animal models that do not include mice, rats, etc, but that might include non-human primates, cats, dogs, and others." ;
  rdfs:subClassOf obo:NCIT_C71164 .

obo:DOID_3213 a rdfs:Class ;
  rdfs:label "demyelinating disease" ;
  rdfs:comment "A neurodegenerative disease that is characterized by damage to the myelin sheath present around nerve axons." ;
  rdfs:subClassOf obo:DOID_1289 .

obo:DOID_9970 a rdfs:Class ;
  rdfs:label "obesity" ;
  rdfs:comment "An overnutrition that is characterized by excess body fat, traditionally defined as an elevated ratio of weight to height (specifically 30 kilograms per meter squared), has_material_basis_in a multifactorial etiology related to excess nutrition intake, decreased caloric utilization, and genetic susceptibility, and possibly medications and certain disorders of metabolism, endocrine function, and mental illness." ;
  rdfs:subClassOf obo:DOID_654 .

obo:HP_0032057 a rdfs:Class ;
  rdfs:label "Focal cortical dysplasia type IIIc" ;
  rdfs:comment "A subtype of focal cortical dysplasia type III that is characterized by alterations in architectural (cortical dyslamination, hypoplasia) or cytoarchitectural composition of the neocortex (hypertrophic neurons), which occur adjacent to vascular malformations (cavernomas, arteriovenous malformations, leptomeningeal vascular malformations, telangiectasias, meningioangiomatosis)." ;
  rdfs:seeAlso <http://www.case.edu/EpSO.owl#FocalCorticalDysplasiaTypeIIIC> ;
  rdfs:subClassOf obo:HP_0032054 .

obo:HP_0000153 a rdfs:Class ;
  rdfs:label "Abnormality of the mouth" ;
  rdfs:comment "An abnormality of the mouth." ;
  rdfs:subClassOf obo:HP_0000271 .

obo:HP_0011025 a rdfs:Class ;
  rdfs:label "Abnormal cardiovascular system physiology" ;
  rdfs:comment "Abnormal functionality of the cardiovascular system." ;
  rdfs:subClassOf obo:HP_0001626 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#Panayiotopoulos_syndrome> a rdfs:Class ;
  rdfs:label "Panayiotopoulos syndrome" ;
  rdfs:subClassOf obo:MONDO_0020072 .

obo:SYMP_0000061 a rdfs:Class ;
  rdfs:label "inflammation" ;
  rdfs:comment "Inflammation is a general symptom where there is a local response to cellular injury that is marked by capillary dilatation, leukocytic infiltration, redness, heat, pain, swelling, and often loss of function and that serves as a mechanism initiating the elimination of noxious agents and of damaged tissue." ;
  rdfs:seeAlso <http://www.case.edu/EpSO.owl#Inflammation> ;
  rdfs:subClassOf obo:SYMP_0000567 .

obo:HP_0011729 a rdfs:Class ;
  rdfs:label "Abnormality of joint mobility" ;
  rdfs:comment "An abnormality in the range and ease of motion of joints across their normal range." ;
  rdfs:subClassOf obo:HP_0011843 .

obo:NCIT_C17883 a rdfs:Class ;
  rdfs:label "Palliative Surgery" ;
  rdfs:comment "Surgery that does not alter the course of a disease, but improves the quality of life." ;
  rdfs:subClassOf obo:NCIT_C161601 .

obo:DOID_5844 a rdfs:Class ;
  rdfs:label "myocardial infarction" ;
  rdfs:comment "A coronary artery disease characterized by myocardial cell death (myocardial necrosis) due to prolonged ischaemia." ;
  rdfs:subClassOf obo:DOID_3393 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy/brain_connectivity_TM_BIN> a rdfs:Class ;
  rdfs:label "Brain connectivity TM_BIN" .

obo:UBERON_0002728 a rdfs:Class ;
  rdfs:label "entorhinal cortex" ;
  rdfs:comment "Component of the temporal lobe on the mesial surface. The rostral and caudal boundaries of the entorhinal cortex are the rostral end of the collateral sulcus and the caudal end of the amygdala respectively. The medial boundary is the medial aspect of the temporal lobe and the lateral boundary is the collateral sulcus. (DK)." ;
  rdfs:subClassOf obo:UBERON_0000064 .

obo:UBERON_0008930 a rdfs:Class ;
  rdfs:label "somatosensory cortex" ;
  rdfs:comment "Area of the parietal lobe concerned with receiving general sensations. It lies posterior to the central sulcus." ;
  rdfs:subClassOf obo:UBERON_0035014 .

obo:NCIT_C94198 a rdfs:Class ;
  rdfs:label "Cardiac Pacemaker" ;
  rdfs:subClassOf obo:OBI_0000968 .

obo:MONDO_0021042 a rdfs:Class ;
  rdfs:label "glioma" ;
  rdfs:comment "A benign or malignant brain and spinal cord tumor that arises from glial cells (astrocytes, oligodendrocytes, ependymal cells). Tumors that arise from astrocytes are called astrocytic tumors or astrocytomas. Tumors that arise from oligodendrocytes are called oligodendroglial tumors. Tumors that arise from ependymal cells are called ependymomas." ;
  rdfs:seeAlso <http://www.case.edu/EpSO.owl#Glioma> ;
  rdfs:subClassOf obo:MONDO_0021193 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#pedaling> a rdfs:Class ;
  rdfs:label "pedaling" ;
  rdfs:subClassOf obo:SYMP_0000891 .

obo:NCIT_C15315 a rdfs:Class ;
  rdfs:label "Rehabilitation" ;
  rdfs:comment "Restoration of the ability to function in a normal or near normal manner following disease, illness, or injury." ;
  rdfs:subClassOf obo:NCIT_C15747 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#partial_amnesia> a rdfs:Class ;
  rdfs:label "partial amnesia" ;
  rdfs:seeAlso <https://www.verywellhealth.com/amnesia-and-memory-loss-2161855> ;
  rdfs:subClassOf obo:SYMP_0000719 .

obo:NCIT_C15420 a rdfs:Class ;
  rdfs:label "Hypnotherapy" ;
  rdfs:comment "Therapeutic use of hypnotism by a clinical professional." ;
  rdfs:seeAlso <https://hypnosementor.nl/en/the-use-of-hypnosis-with-epilepsy/> ;
  rdfs:subClassOf obo:NCIT_C15308 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#toxic_cause_of_seizure> a rdfs:Class ;
  rdfs:label "toxic cause of seizure" ;
  rdfs:subClassOf obo:NCIT_C17103 .

obo:NBO_0000493 a rdfs:Class ;
  rdfs:label "parasomnia" ;
  rdfs:comment "\"A sleeping behavior phenotype that involve abnormal and unnatural movements, emotions, perceptions, and dreams that occur while falling asleep, sleeping, between sleep stages, or during arousal from sleep.\" [wikipedia:Parasomnia]" ;
  rdfs:seeAlso <http://www.case.edu/EpSO.owl#Parasomnias> ;
  rdfs:subClassOf obo:DOID_535 .

obo:OMIT_0016978 a rdfs:Class ;
  rdfs:label "Head Injuries, Closed" ;
  rdfs:subClassOf obo:NCIT_C34660 .

obo:DOID_13317 a rdfs:Class ;
  rdfs:label "hyperinsulinemic hypoglycemia" ;
  rdfs:comment "A carbohydrate metabolic disorder that involves low blood glucose resulting from an excess of insulin." ;
  rdfs:subClassOf obo:DOID_2978 .

obo:MONDO_0019104 a rdfs:Class ;
  rdfs:label "Sandifer syndrome" ;
  rdfs:comment "Sandifer syndrome is a paroxysmal dystonic movement disorder occurring in association with gastro-oesophageal reflux, and, in some cases, hiatal hernia." ;
  rdfs:subClassOf obo:NCIT_C69023 .

obo:NBO_0000747 a rdfs:Class ;
  rdfs:label "jaw movement" ;
  rdfs:subClassOf obo:NBO_0000007 .

obo:DOID_0050155 a rdfs:Class ;
  rdfs:label "sensory system disease" ;
  rdfs:comment "A nervous system disease which is located in a part of the nervous system responsible for processing sensory information that consists of sensory receptors, neural pathways, and parts of the brain involved in sensory perception. Commonly recognized sensory systems are those for vision, hearing, somatic sensation (touch), taste and olfaction (smell)." ;
  rdfs:subClassOf obo:DOID_863 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#paroxysmal_dystonia_model> a rdfs:Class ;
  rdfs:label "paroxysmal dystonia model" ;
  rdfs:subClassOf obo:NCIT_C19272 .

obo:SYMP_0000387 a rdfs:Class ;
  rdfs:label "head symptom" ;
  rdfs:subClassOf obo:SYMP_0000597 .

obo:ERO_0001508 a rdfs:Class ;
  rdfs:label "karyotyping" ;
  rdfs:comment "A molecular assay used to determine the number and appearance of chromosomes in the nucleus of a eukaryotic cell." ;
  rdfs:subClassOf obo:ERO_0000833 .

obo:DOID_0050635 a rdfs:Class ;
  rdfs:label "alternating hemiplegia of childhood" ;
  rdfs:comment "A hemiplegia characterized by recurrent episodes of temporary weakness or complete paralysis on one or both sides of the body." ;
  rdfs:subClassOf obo:MONDO_0017657 .

obo:UBERON_0013543 a rdfs:Class ;
  rdfs:label "Brodmann (1909) area 12" ;
  rdfs:comment "Brodmann area 12 is a subdivision of the cerebral cortex of the guenon defined on the basis of cytoarchitecture. It occupies the most rostral portion of the frontal lobe. Brodmann-1909 did not regard it as homologous, either topographically or cytoarchitecturally, to rostral area 12 of the human. Distinctive features (Brodmann-1905): a quite distinct internal granular layer (IV) separates slender pyramidal cells of the external pyramidal layer (III) and the internal pyramidal layer (V); the multiform layer (VI) is expanded, contains widely dispersed spindle cells and merges gradually with the underlying cortical white matter; all cells, including the pyramidal cells of the external and internal pyramidal layers are inordinately small; the internal pyramidal layer (V) also contains spindle cells in groups of two to five located close to its border with the internal granular layer (IV)." ;
  rdfs:subClassOf obo:UBERON_0013529 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#autonomic_imbalance> a rdfs:Class ;
  rdfs:label "autonomic imbalance" ;
  rdfs:subClassOf obo:SYMP_0000480 .

obo:MONDO_0015650 a rdfs:Class ;
  rdfs:label "epilepsy syndrome" ;
  rdfs:subClassOf <https://bio.scai.fraunhofer.de/ontology/epilepsy#International_League_Against_Epilepsy_classification> .

obo:DOID_591 a rdfs:Class ;
  rdfs:label "phobic disorder" ;
  rdfs:comment "An anxiety disorder where fear and anxiety are triggered by a specific stimulus or situation." ;
  rdfs:subClassOf obo:DOID_2030 .

obo:UBERON_0001872 a rdfs:Class ;
  rdfs:label "parietal lobe" ;
  rdfs:comment "Upper central part of the cerebral hemisphere. (MSH)" ;
  rdfs:subClassOf obo:UBERON_0016526 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#focal_sensory_seizure_with_cephalic_sensation> a rdfs:Class ;
  rdfs:label "focal sensory seizure with cephalic sensation" ;
  rdfs:subClassOf obo:HP_0011157 .

obo:BFO_0000011 a rdfs:Class ;
  rdfs:label "spatiotemporal region" ;
  rdfs:subClassOf obo:BFO_0000003 .

obo:MONDO_0100026 a rdfs:Class ;
  rdfs:label "myoclonic encephalopathy in non-progressive disorder" ;
  rdfs:comment "This group of epilepsies are typically is characterized by onset of seizures from day 1 of life to 5 years (peak 12 months). Both sexes are affected, however the male to female ratio is 1:2. Antecedent (including birth) history, head size, neurological and developmental findings reflect the underlying cause (if known). Myoclonic status epilepticus is often the initial presenting seizure type, however other initial seizure types may also occur. Prognosis is unfavorable with severe neurological and developmental impairments typically seen." ;
  rdfs:subClassOf obo:MONDO_0100022 .

obo:CMO_0000921 a rdfs:Class ;
  rdfs:label "platelet measurement" ;
  rdfs:seeAlso <https://www.epilepsy.com/learn/treating-seizures-and-epilepsy/seizure-and-epilepsy-medicines/blood-testing> ;
  rdfs:subClassOf obo:CMO_0000036 .

obo:BFO_0000040 a rdfs:Class ;
  rdfs:label "material entity" ;
  rdfs:subClassOf obo:BFO_0000004 .

obo:DOID_0050561 a rdfs:Class ;
  rdfs:label "Lennox-Gastaut syndrome" ;
  rdfs:comment "A childhood electroclinical syndrome that is characterized by frequent seizures and intellectual disability that present in early childhood." ;
  rdfs:subClassOf obo:MONDO_0020072 .

obo:HP_0011154 a rdfs:Class ;
  rdfs:label "Focal autonomic seizure" ;
  rdfs:comment "Focal seizures with an objectively documented and distinct alteration of autonomic nervous system function involving cardiovascular, pupillary, gastrointestinal, sudomotor, vasomotor and thermoregularity functions." ;
  rdfs:subClassOf <https://bio.scai.fraunhofer.de/ontology/epilepsy#focal_non-motor_onset_seizure> .

obo:HP_0100770 a rdfs:Class ;
  rdfs:label "Hyperperistalsis" ;
  rdfs:comment "Excessively active peristalsis (wave of contraction of the tubular organs of the gastrointestinal tract) marked by excessive rapidity of the passage of food through the stomach and intestine." ;
  rdfs:subClassOf obo:HP_0030914 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#picrotoxin-induced_seizure> a rdfs:Class ;
  rdfs:label "picrotoxin-induced seizure" ;
  rdfs:subClassOf <https://bio.scai.fraunhofer.de/ontology/epilepsy#toxic_cause_of_seizure> .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#frontal_lobe_seizure> a rdfs:Class ;
  rdfs:label "frontal lobe seizure" ;
  rdfs:seeAlso <https://www.mayoclinic.org/diseases-conditions/frontal-lobe-seizures/symptoms-causes/syc-20353958> ;
  rdfs:subClassOf <https://bio.scai.fraunhofer.de/ontology/epilepsy#seizure_based_on_lobar_localization> .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#conventional_electroencephalography> a rdfs:Class ;
  rdfs:label "conventional electroencephalography" ;
  rdfs:subClassOf obo:OBI_0002186 .

obo:MONDO_0017656 a rdfs:Class ;
  rdfs:label "motor stereotypies" ;
  rdfs:subClassOf obo:DOID_480 .

obo:NBO_0000003 a rdfs:Class ;
  rdfs:label "emotional behavior" ;
  rdfs:comment "\"Behavior related to the complex psychophysiological experience of an individual's state of mind as interacting with biochemical (internal) and environmental (external) influences.\" [wikipedia:Emotions]" ;
  rdfs:subClassOf obo:NBO_0000313 .

obo:NCIT_C71164 a rdfs:Class ;
  rdfs:label "Animal Model" ;
  rdfs:comment "An animal that is amenable to experimentation and whose physiological or pathologic mechanisms are sufficiently similar to those of a human for the animal to serve as a model." ;
  rdfs:subClassOf obo:NCIT_C19148 .

obo:UBERON_0015593 a rdfs:Class ;
  rdfs:label "frontal gyrus" ;
  rdfs:comment "A gyrus that is part of a frontal cortex." ;
  rdfs:subClassOf obo:UBERON_0000200 .

obo:NCIT_C34660 a rdfs:Class ;
  rdfs:label "Head Injury" ;
  rdfs:comment "A traumatic injury to the head." ;
  rdfs:subClassOf obo:OGMS_0000102 .

obo:DOID_255 a rdfs:Class ;
  rdfs:label "hemangioma" ;
  rdfs:comment "A cardiovascular organ benign neoplasm that has_material_basis_in endothelial cells that line blood vessels and is characterised by increased number of normal or abnormal vessels filled with blood." ;
  rdfs:subClassOf obo:DOID_0060084 , obo:DOID_0060091 .

obo:HP_0000571 a rdfs:Class ;
  rdfs:label "Hypometric saccades" ;
  rdfs:comment "Saccadic undershoot, i.e., a saccadic eye movement that has less than the magnitude that would be required to gain fixation of the object." ;
  rdfs:subClassOf obo:HP_0000570 .

obo:UBERON_0010000 a rdfs:Class ;
  rdfs:label "multicellular anatomical structure" ;
  rdfs:comment "An anatomical structure that has more than one cell as a part." ;
  rdfs:subClassOf obo:UBERON_0000061 .

obo:OBI_0000070 a rdfs:Class ;
  rdfs:label "assay" ;
  rdfs:comment "A planned process with the objective to produce information about some evaluant" ;
  rdfs:subClassOf obo:OBI_0000011 .

obo:DOID_104 a rdfs:Class ;
  rdfs:label "bacterial infectious disease" ;
  rdfs:comment "A disease by infectious agent that results_in infection, has_material_basis_in Bacteria." ;
  rdfs:subClassOf obo:DOID_0050117 .

obo:HP_0011204 a rdfs:Class ;
  rdfs:label "EEG with continuous slow activity" ;
  rdfs:comment "EEG showing diffuse slowing without interruption." ;
  rdfs:subClassOf obo:HP_0010845 .

obo:HP_0012639 a rdfs:Class ;
  rdfs:label "Abnormality of nervous system morphology" ;
  rdfs:comment "A structural anomaly of the nervous system." ;
  rdfs:subClassOf obo:HP_0000707 .

obo:UBERON_0035933 a rdfs:Class ;
  rdfs:label "paracentral lobule" ;
  rdfs:comment "The junction of the precentral gyrus and postcentral gyrus on the medial surface of the cerebral cortex. It lies across the boundary between the frontal lobe and the parietal lobe." ;
  rdfs:subClassOf obo:UBERON_0000200 .

obo:CMO_0000183 a rdfs:Class ;
  rdfs:label "head circumference" ;
  rdfs:subClassOf obo:CMO_0000182 .

obo:RS_0001877 a rdfs:Class ;
  rdfs:label "F344-Scn1am1Kyo" ;
  rdfs:subClassOf obo:RS_0000461 .

obo:DOID_4428 a rdfs:Class ;
  rdfs:label "dyslexia" ;
  rdfs:comment "A reading disorder resulting from a developmental reading disability involving the inability to process graphic symbols resulting in impairment of reading ability." ;
  rdfs:seeAlso <https://www.epilepsydiagnosis.org/seizure/cognitive-overview.html> ;
  rdfs:subClassOf obo:DOID_13365 .

obo:UBERON_0004086 a rdfs:Class ;
  rdfs:label "brain ventricle" ;
  rdfs:comment "one of the system of communicating cavities in the brain that are continuous with the central canal of the spinal cord, that like it are derived from the medullary canal of the embryo, that are lined with an epithelial ependyma, and that contain a serous fluid" ;
  rdfs:subClassOf obo:UBERON_0003947 , obo:UBERON_0005358 .

obo:NCBITaxon_10090 a rdfs:Class ;
  rdfs:label "Mus musculus" ;
  rdfs:subClassOf obo:NCBITaxon_9989 .

obo:HP_0001269 a rdfs:Class ;
  rdfs:label "Hemiparesis" ;
  rdfs:comment "Loss of strength in the arm, leg, and sometimes face on one side of the body. Hemiplegia refers to a complete loss of strength, whereas hemiparesis refers to an incomplete loss of strength." ;
  rdfs:subClassOf obo:HP_0004374 .

obo:MONDO_0020308 a rdfs:Class ;
  rdfs:label "benign childhood occipital epilepsy, Gastaut type" ;
  rdfs:comment "Benign childhood occipital epilepsy, Gastaut type is a rare, genetic neurological disorder characterized by childhood to mid-adolescence onset of frequent, brief, diurnal simple partial seizures which usually begin with visual hallucinations (e.g. phosphenes) and/or ictal blindness and may associate non visual seizures (such as deviation of the eyes, oculoclonic seizures), forced eyelid closure and blinking and sensory hallucinations. Post-ictal headache is common while impairment of consciousness is rare." ;
  rdfs:subClassOf obo:MONDO_0020072 .

obo:NCIT_C116585 a rdfs:Class ;
  rdfs:label "Subdural Hematoma" ;
  rdfs:comment "A collection of blood between the dura mater and the brain." ;
  rdfs:seeAlso <https://www.medpagetoday.com/resource-centers/contemporary-advances-epilepsy/determining-risk-seizures-patients-subdural-hematomas/2090> ;
  rdfs:subClassOf obo:SYMP_0000874 .

obo:UBERON_0011215 a rdfs:Class ;
  rdfs:label "central nervous system cell part cluster" ;
  rdfs:comment "A multi cell part structure that is part of a central nervous system." ;
  rdfs:subClassOf obo:UBERON_0005162 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#single_seizure_or_isolated_clusters_of_seizure> a rdfs:Class ;
  rdfs:label "single seizure or isolated clusters of seizure" ;
  rdfs:subClassOf obo:SYMP_0000124 .

obo:MP_0006082 a rdfs:Class ;
  rdfs:label "CNS inflammation" ;
  rdfs:comment "local accumulation of fluid, plasma proteins, and leukocytes in the brain and/or spinal cord" ;
  rdfs:subClassOf obo:MP_0001846 .

obo:SYMP_0000124 a rdfs:Class ;
  rdfs:label "seizure" ;
  rdfs:subClassOf obo:SYMP_0000480 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#background_slow_activity> a rdfs:Class ;
  rdfs:label "background slow activity" ;
  rdfs:subClassOf obo:HP_0011203 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#seizure_classification> a rdfs:Class ;
  rdfs:label "seizure classification" ;
  rdfs:subClassOf <https://bio.scai.fraunhofer.de/ontology/epilepsy#International_League_Against_Epilepsy_classification> .

obo:HP_0032658 a rdfs:Class ;
  rdfs:label "Status epilepticus with prominent motor symptoms" ;
  rdfs:comment "Status epilepticus with prominent motor signs during the prolonged seizure." ;
  rdfs:subClassOf obo:HP_0002133 .

obo:NBO_0000702 a rdfs:Class ;
  rdfs:label "atypical absence seizure" ;
  rdfs:comment "\"An absence seizure not induced by hyperventilation.\" [NBO:GVG]" ;
  rdfs:subClassOf <https://bio.scai.fraunhofer.de/ontology/epilepsy#generalized_non-motor_onset_seizure> .

obo:UBERON_0002911 a rdfs:Class ;
  rdfs:label "parietal operculum" ;
  rdfs:comment "The parietal operculum, forming the superior bank of the sylvian fissure, as studied in the cat, contains the secondary somatosensory representation, 'S-II', and a second somatotopic representation (parietal ventral, or PV). Anatomically, primate S-II receives inputs from area 3 and area 1, and projects to PV and area 7. PV has projections to area 5 and premotor areas. [WP,unvetted]." ;
  rdfs:subClassOf obo:UBERON_0002616 .

obo:DOID_0060004 a rdfs:Class ;
  rdfs:label "autoimmune disease of central nervous system" ;
  rdfs:comment "An autoimmune hypersensitivity disease located_in the central nervous system." ;
  rdfs:subClassOf obo:DOID_438 .

obo:DOID_1679 a rdfs:Class ;
  rdfs:label "cystitis" ;
  rdfs:comment "A bladder disease that is characterized by inflammation of the bladder." ;
  rdfs:subClassOf obo:DOID_365 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#oligoantigenic_diet> a rdfs:Class ;
  rdfs:label "oligoantigenic diet" ;
  rdfs:subClassOf obo:OMIT_0005305 .

obo:DOID_3687 a rdfs:Class ;
  rdfs:label "MELAS syndrome" ;
  rdfs:comment "A mitochondrial encephalomyopathy that is characterized by mitochondrial myopathy, encephalopathy, lactic acidosis, and stroke-like episodes, has_symptom myalgia, motor weakness, headaches, seizures, and stroke-like episodes with acute hemiparesis and severe headaches, and develops_from mutation in mitochondrial genes including MT-TL1, which encodes tRNA proteins." ;
  rdfs:seeAlso <http://www.case.edu/EpSO.owl#MitochondrialEncephalomyopathyLacticAcidosisStrokelikeEpisodes> ;
  rdfs:subClassOf obo:MONDO_0044970 .

obo:MONDO_0018199 a rdfs:Class ;
  rdfs:label "new-onset refractory status epilepticus" ;
  rdfs:comment "New-onset refractory status epilepticus is an acute encephalopathy with inflammation-mediated status epilepticus characterized by an acute refractory status epilepticus, typically of the tonic-clonic type, following prodromal symptoms of confusion, fever, fatigue, headache, symptoms of gastrointestinal or upper respiratory tract infection, behavioral changes or hallucinations. Brain MRI abnormalities and abnormal findings in CSF, including pleocytosis and/or elevated protein levels, are frequently found during acute episode. Treatment-resistant epilepsy, cognitive and psychiatric impairments are usual consequences." ;
  rdfs:subClassOf obo:MONDO_0018200 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#structural_equation_model> a rdfs:Class ;
  rdfs:label "structural equation model" ;
  rdfs:subClassOf <https://bio.scai.fraunhofer.de/ontology/epilepsy#non-deterministic_model> .

obo:UBERON_0002028 a rdfs:Class ;
  rdfs:label "hindbrain" ;
  rdfs:comment "The most posterior of the three principal regions of the brain. In mammals and birds the hindbrain is divided into a rostral metencephalon and a caudal myelencephalon. In zebrafish, with the exception of the cerebellum, the ventral remainder of the metencephalon can be separated only arbitrarily from the more caudal myelencephalic portion of the medulla oblongata (From: Neuroanatomy of the Zebrafish Brain)[ZFA]. Organ component of neuraxis that has as its parts the pons, cerebellum and medulla oblongata[FMA]." ;
  rdfs:subClassOf obo:UBERON_0002616 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#sleep_electroencephalography> a rdfs:Class ;
  rdfs:label "sleep electroencephalography" ;
  rdfs:seeAlso <https://www.nhs.uk/conditions/electroencephalogram/> ;
  rdfs:subClassOf obo:OBI_0002186 .

obo:DOID_8506 a rdfs:Class ;
  rdfs:label "bullous pemphigoid" ;
  rdfs:comment "An autoimmune disease of skin and connective tissue characterized by large blisters." ;
  rdfs:subClassOf obo:DOID_0060039 .

obo:UBERON_0004718 a rdfs:Class ;
  rdfs:label "Brodmann (1909) area 26" ;
  rdfs:comment "." ;
  rdfs:subClassOf obo:UBERON_0013529 .

obo:NCIT_C118177 a rdfs:Class ;
  rdfs:label "Gustatory Hallucination" ;
  rdfs:comment "Perception of a taste in the absence of a corresponding stimulus." ;
  rdfs:subClassOf obo:NBO_0000308 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#adversive_movement> a rdfs:Class ;
  rdfs:label "adversive movement" ;
  rdfs:subClassOf obo:HP_0011175 .

obo:MONDO_0005132 a rdfs:Class ;
  rdfs:label "cytomegalovirus infection" ;
  rdfs:comment "A herpesvirus infection caused by Cytomegalovirus. Healthy individuals generally do not produce symptoms. However, the infection may be life-threatening in affected immunocompromised patients. The virus may cause retinitis, esophagitis, gastritis, and colitis. Morphologically, it is characterized by the presence of intranuclear inclusion bodies." ;
  rdfs:subClassOf <https://bio.scai.fraunhofer.de/ontology/epilepsy#infectious_etiology> .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#anterior_temporal_epilepsy> a rdfs:Class ;
  rdfs:label "anterior temporal epilepsy" ;
  rdfs:seeAlso <http://www.case.edu/EpSO.owl#AnteriorTemporalEpilepsy> ;
  rdfs:subClassOf obo:DOID_3328 .

obo:NBO_0000476 a rdfs:Class ;
  rdfs:label "intrinsic sleep disorder" ;
  rdfs:subClassOf obo:NBO_0000475 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#status_pattern> a rdfs:Class ;
  rdfs:label "status pattern" ;
  rdfs:seeAlso <http://www.case.edu/EpSO.owl#StatusPattern> ;
  rdfs:subClassOf <https://bio.scai.fraunhofer.de/ontology/epilepsy#ictal_pattern> .

obo:HP_0002917 a rdfs:Class ;
  rdfs:label "Hypomagnesemia" ;
  rdfs:comment "An abnormally decreased magnesium concentration in the blood." ;
  rdfs:seeAlso <https://www.epilepsy.com/learn/professionals/co-existing-disorders/metabolic-disorders/electrolyte-abnormalities> ;
  rdfs:subClassOf obo:HP_0004921 .

obo:MONDO_0020072 a rdfs:Class ;
  rdfs:label "childhood-onset epilepsy syndrome" ;
  rdfs:comment "A epilepsy syndrome that occurs during childhood." ;
  rdfs:seeAlso <https://www.epilepsydiagnosis.org/syndrome/epilepsy-syndrome-groupoverview.html#> ;
  rdfs:subClassOf obo:MONDO_0015650 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#kainic_acid-induced_seizure> a rdfs:Class ;
  rdfs:label "kainic acid-induced seizure" ;
  rdfs:subClassOf <https://bio.scai.fraunhofer.de/ontology/epilepsy#toxic_cause_of_seizure> .

obo:CMO_0001242 a rdfs:Class ;
  rdfs:label "cerebrospinal fluid electrolyte measurement" ;
  rdfs:seeAlso <https://link.springer.com/article/10.1007/BF02075764> ;
  rdfs:subClassOf obo:CMO_0001241 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#focal_cognitive_seizure_with_memory_impairment> a rdfs:Class ;
  rdfs:label "focal cognitive seizure with memory impairment" ;
  rdfs:seeAlso <https://www.epilepsysociety.org.uk/how-epilepsy-can-affect-memory#.XH926ogzbIU> ;
  rdfs:subClassOf <https://bio.scai.fraunhofer.de/ontology/epilepsy#focal_cognitive_seizure> .

<https://bio.scai.fraunhofer.de/ontology/0000501> a rdfs:Class ;
  rdfs:label "functional connectivity" ;
  rdfs:subClassOf <https://bio.scai.fraunhofer.de/ontology/0000500> .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#language_regression_due_to_other_etiology> a rdfs:Class ;
  rdfs:label "language regression due to other etiology" ;
  rdfs:seeAlso <https://www.epilepsydiagnosis.org/syndrome/lks-diffdiagnoses.html> ;
  rdfs:subClassOf obo:MONDO_0020072 .

<https://bio.scai.fraunhofer.de/ontology/0000419> a rdfs:Class ;
  rdfs:label "cellular process TM_BIN" ;
  rdfs:comment "The 'cellular process TM_BIN' concept enables a compilation of diverse concepts that are related to cellular processes in Epilepsy via the Axiome 'isAnatomicalEntityFor some epilepsy'.  Thus enables the adaptation of the ontology for text mining purposes for Epilepsy related information retrieval and information extraction." .

obo:HP_0002715 a rdfs:Class ;
  rdfs:label "Abnormality of the immune system" ;
  rdfs:comment "An abnormality of the immune system." ;
  rdfs:subClassOf obo:HP_0000118 .

obo:MONDO_0016027 a rdfs:Class ;
  rdfs:label "benign neonatal seizures" ;
  rdfs:comment "Benign familial neonatal epilepsy (BFNE) is a rare genetic epilepsy syndrome characterized by the occurrence of afebrile seizures in otherwise healthy newborns with onset in the first few days of life." ;
  rdfs:subClassOf obo:MONDO_0020070 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#focal_cognitive_seizure_with_dyslexia/alexia> a rdfs:Class ;
  rdfs:label "focal cognitive seizure with dyslexia/alexia" ;
  rdfs:subClassOf <https://bio.scai.fraunhofer.de/ontology/epilepsy#focal_cognitive_seizure> .

obo:NCIT_C103519 a rdfs:Class ;
  rdfs:label "Generalized Anxiety Disorder - 7 Questionnaire" ;
  rdfs:comment "A seven item validated, self-reported questionnaire for screening, and assessing the severity of generalized anxiety disorder in clinical practice and research settings." ;
  rdfs:subClassOf obo:NCIT_C91105 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#hypothalamic_epilepsy> a rdfs:Class ;
  rdfs:label "hypothalamic epilepsy" ;
  rdfs:seeAlso <http://www.case.edu/EpSO.owl#HypothalamicEpilepsy> ;
  rdfs:subClassOf <https://bio.scai.fraunhofer.de/ontology/epilepsy#simple_focal_seizure> .

obo:NBO_0000589 a rdfs:Class ;
  rdfs:label "tremor" ;
  rdfs:comment "\"An involuntary rhythmical, oscillatory movement of a body part.\" [NBO:GVG]" ;
  rdfs:seeAlso <https://genetic.org/wp-content/uploads/2017/07/Elizabeth-Berry-Kravis-seizures-and-tremor-AXYS-2017.pdf> ;
  rdfs:subClassOf obo:NBO_0000643 .

obo:RS_0001318 a rdfs:Class ;
  rdfs:label "GRY/Idr" ;
  rdfs:subClassOf obo:RS_0000765 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#episodic_ataxia_type-1_model> a rdfs:Class ;
  rdfs:label "episodic ataxia type-1 model" ;
  rdfs:subClassOf <https://bio.scai.fraunhofer.de/ontology/epilepsy#chemical_mutagenesis_derived_model> .

obo:DOID_0060410 a rdfs:Class ;
  rdfs:label "chromosome 1p36 deletion syndrome" ;
  rdfs:subClassOf obo:MONDO_0019040 .

obo:PATO_0000133 a rdfs:Class ;
  rdfs:label "orientation" ;
  rdfs:comment "A spatial quality inhering in a bearer by virtue of the bearer's placement which is defined by the angle between the bearer and an axis, or the angle between the bearer and another object." ;
  rdfs:subClassOf obo:PATO_0000140 .

obo:MF_0000033 a rdfs:Class ;
  rdfs:label "mental disposition" ;
  rdfs:comment "A mental disposition is a bodily disposition that is realized in a mental process. " ;
  rdfs:subClassOf obo:BFO_0000016 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#complex_febrile_model> a rdfs:Class ;
  rdfs:label "complex febrile model" ;
  rdfs:subClassOf <https://bio.scai.fraunhofer.de/ontology/epilepsy#hyperthermic_seizure_model> .

obo:HP_0012000 a rdfs:Class ;
  rdfs:label "EEG with generalized spikes" ;
  rdfs:comment "EEG with generalized sharp transient waves of a duration less than 80 msec." ;
  rdfs:seeAlso <http://www.case.edu/EpSO.owl#Spike> ;
  rdfs:subClassOf obo:HP_0011198 .

obo:UBERON_0008934 a rdfs:Class ;
  rdfs:label "secondary somatosensory cortex" ;
  rdfs:comment "the area of the upper bank of the lateral sulcus that is involved in somatic sensation" ;
  rdfs:subClassOf obo:UBERON_0008930 .

obo:DOID_0050741 a rdfs:Class ;
  rdfs:label "alcohol dependence" ;
  rdfs:comment "A substance dependence that is characterized by tolerance, withdrawal symptoms, increasing use, persistent desire to decrease consumption, time spent obtaining or recovering from alcohol caused by a physical and psychological dependence on alcohol." ;
  rdfs:subClassOf obo:DOID_9973 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#sharp_and_slow_wave_complex> a rdfs:Class ;
  rdfs:label "sharp and slow wave complex" ;
  rdfs:subClassOf obo:HP_0025373 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#first_line_immunotherapy> a rdfs:Class ;
  rdfs:label "first line immunotherapy" ;
  rdfs:subClassOf obo:OGMS_0000114 .

obo:DOID_0060056 a rdfs:Class ;
  rdfs:label "hypersensitivity reaction disease" ;
  rdfs:comment "An immune system disease that has_material_basis_in abnormal immune responses." ;
  rdfs:subClassOf obo:DOID_2914 .

obo:MONDO_0019052 a rdfs:Class ;
  rdfs:label "inborn errors of metabolism" ;
  rdfs:comment "A group of disorders present at birth that involve genetic defects leading to disturbances in carbohydrate, lipid, lysosomal storage or amino acid metabolism in the body. The inborn errors of metabolism are typically rare, but this class also encompasses non-rare diseases like hereditary hemochromatosis type 1" ;
  rdfs:subClassOf obo:DOID_0014667 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#focal_seizure_classification_by_onset_feature> a rdfs:Class ;
  rdfs:label "focal seizure classification by onset feature" ;
  rdfs:subClassOf obo:HP_0007359 .

obo:CMO_0002341 a rdfs:Class ;
  rdfs:label "white blood cell measurement" ;
  rdfs:seeAlso <https://www.webmd.com/epilepsy/guide/epilepsy-blood-test> ;
  rdfs:subClassOf obo:CMO_0000036 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#hypehydrotic_seizure> a rdfs:Class ;
  rdfs:label "hypehydrotic seizure" ;
  rdfs:seeAlso <http://www.case.edu/EpSO.owl#HypehydroticSeizure> ;
  rdfs:subClassOf obo:SYMP_0000124 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#focal_autonomic_seizure_with_hypoventilation/hyperventilation/altered_respiration> a rdfs:Class ;
  rdfs:label "focal autonomic seizure with hypoventilation/hyperventilation/altered respiration" ;
  rdfs:seeAlso <https://www.epilepsydiagnosis.org/seizure/autonomic-overview.html> ;
  rdfs:subClassOf obo:HP_0011154 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#bicuculline_model> a rdfs:Class ;
  rdfs:label "bicuculline model" ;
  rdfs:subClassOf <https://bio.scai.fraunhofer.de/ontology/epilepsy#convulsant_drug_model> .

obo:NBO_0000130 a rdfs:Class ;
  rdfs:label "liquid consumption" ;
  rdfs:comment "\"A behavior associated with the intake of liquid.\" [NBO:GVG]" ;
  rdfs:subClassOf obo:NBO_0000079 .

obo:BFO_0000027 a rdfs:Class ;
  rdfs:label "object aggregate" ;
  rdfs:subClassOf obo:BFO_0000040 .

<https://bio.scai.fraunhofer.de/ontology/mental_disorder#cognitive_symptom> a rdfs:Class ;
  rdfs:label "cognitive symptom" ;
  rdfs:seeAlso <https://livingwithschizophreniauk.org/cognitive-symptoms-schizophrenia/> ;
  rdfs:subClassOf obo:SYMP_0000480 .

obo:SYMP_0000564 a rdfs:Class ;
  rdfs:label "nocturia" ;
  rdfs:comment "Nocturia is a urinary system symptom characterized by urination at night especially when excessive." ;
  rdfs:seeAlso <http://www.case.edu/EpSO.owl#Nocturia> ;
  rdfs:subClassOf obo:SYMP_0000486 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#AMPA_receptor_antibody> a rdfs:Class ;
  rdfs:label "AMPA receptor antibody" ;
  rdfs:subClassOf obo:MONDO_0100029 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#dreamy_state> a rdfs:Class ;
  rdfs:label "dreamy state" ;
  rdfs:subClassOf obo:NBO_0000609 .

obo:MP_0001846 a rdfs:Class ;
  rdfs:label "increased inflammatory response" ;
  rdfs:comment "greater than expected response to injury, infection, or insult" ;
  rdfs:subClassOf obo:MP_0001845 .

obo:ERO_0001183 a rdfs:Class ;
  rdfs:label "next generation DNA sequencing" ;
  rdfs:comment "A DNA sequencing technique that became commercially available in 2004 and is used by specific commercial platforms that embody a complex interplay of enzymology, chemistry, high-resolution optics, hardware, and software engineering. These instruments allow highly streamlined sample preparation steps prior to DNA sequencing, which provides a significant time savings and a minimal requirement for associated equipment in comparison to the highly automated, multistep pipelines necessary for clone-based high-throughput sequencing. Each technology amplifies single strands of a fragment library and perform sequencing reactions on the amplified strands. The fragment libraries are obtained by annealing platform-specific linkers to blunt-ended fragments generated directly from a genome or DNA source of interest. Because the presence of adapter sequences means that the molecules then can be selectively amplified by PCR, and no bacterial cloning step is required to amplify the genomic fragment in a bacterial intermediate as is done in traditional sequencing approaches." ;
  rdfs:subClassOf obo:OBI_0000626 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#episodic_ataxia_type-2_model> a rdfs:Class ;
  rdfs:label "episodic ataxia type-2 model" ;
  rdfs:subClassOf <https://bio.scai.fraunhofer.de/ontology/epilepsy#chemical_mutagenesis_derived_model> .

obo:ERO_0001235 a rdfs:Class ;
  rdfs:label "magnetic resonance imaging" ;
  rdfs:comment "A physiological assay that uses nuclear magnetic resonance of protons to produce proton density images." ;
  rdfs:subClassOf obo:ERO_0001292 .

obo:PW_0001140 a rdfs:Class ;
  rdfs:label "calcium/calcium-mediated signaling pathway" ;
  rdfs:comment "Calcium signaling impacts on a large and diverse spectrum of cellular processes such as gene expression and cell death, proliferation, muscle contraction and energy metabolism, learning, memory and synaptic plasticity. Calcium acts in signal transduction as a first as well as a second messenger. Calcium transport, which controls and maintains the calcium gradient, and calcium signaling, which the gradient promotes, are inextricably connected in the fabric of calcium homeostasis." ;
  rdfs:subClassOf obo:GO_0007165 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#invasive_preoperative_exploration> a rdfs:Class ;
  rdfs:label "invasive preoperative exploration" ;
  rdfs:subClassOf obo:NCIT_C139982 .

obo:HP_0004305 a rdfs:Class ;
  rdfs:label "Involuntary movements" ;
  rdfs:comment "Involuntary contractions of muscle leading to involuntary movements of extremities, neck, trunk, or face." ;
  rdfs:subClassOf obo:HP_0100022 .

obo:OMIT_0027103 a rdfs:Class ;
  rdfs:label "Endophenotypes" ;
  rdfs:subClassOf obo:BFO_0000019 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#heautoscopy> a rdfs:Class ;
  rdfs:label "heautoscopy" ;
  rdfs:subClassOf obo:NBO_0000609 .

obo:OMIT_0004981 a rdfs:Class ;
  rdfs:label "Delta Rhythm" ;
  rdfs:seeAlso <http://www.case.edu/EpSO.owl#DeltaRhythm> , <https://emedicine.medscape.com/article/1139332-overview#a1> ;
  rdfs:subClassOf obo:OMIT_0027154 .

obo:SYMP_0000005 a rdfs:Class ;
  rdfs:label "ataxia" ;
  rdfs:comment "Ataxia is a neurological and physiological symptom characterized by an inability to coordinate voluntary muscular movements that is symptomatic of some nervous disorders." ;
  rdfs:subClassOf obo:SYMP_0000410 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#simple_visual_hallucination> a rdfs:Class ;
  rdfs:label "simple visual hallucination" ;
  rdfs:seeAlso <http://www.case.edu/EpSO.owl#SimpleVisualHallucination> ;
  rdfs:subClassOf obo:NBO_0000609 .

obo:NCIT_C65017 a rdfs:Class ;
  rdfs:label "Nutritional Therapy" ;
  rdfs:seeAlso <https://www.epilepsy.com/living-epilepsy/healthy-living/healthy-eating/nutrition-and-seizure-control> ;
  rdfs:subClassOf obo:OGMS_0000112 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#insular_epilepsy> a rdfs:Class ;
  rdfs:label "insular epilepsy" ;
  rdfs:seeAlso <http://www.case.edu/EpSO.owl#InsularEpilepsy> ;
  rdfs:subClassOf <https://bio.scai.fraunhofer.de/ontology/epilepsy#simple_focal_seizure> .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#palinopsia> a rdfs:Class ;
  rdfs:label "palinopsia" ;
  rdfs:seeAlso <http://www.case.edu/EpSO.owl#Palinopsia> ;
  rdfs:subClassOf obo:HP_0000504 .

obo:UBERON_0013529 a rdfs:Class ;
  rdfs:label "Brodmann area" ;
  rdfs:comment "A segmentation of the cerebral cortex on the basis of cytoarchitecture as described in Brodmann-1905, Brodmann-1909 and Brodmann-10. Maps for several species were presented. NeuroNames includes only areas in the human and in Old World monkeys. Of the latter, Brodmann studied representatives of several species including guenons (one Cercopithecus mona, one Cercocebus torquatus, and one Cercopithecus otherwise unspecified), which are all closely related African species, and one macaque (Macaca mulatta) an Asian species (Brodmann-1905). The legend to the summary map in Brodmann-1909 ascribes the areas simply to Cercopithecus. Brodmann referenced the areas by name and number. The same area number in humans and monkeys did not necessarily refer to topologically or cytoarchitecturally homologous structures. In NeuroNames the standard term for human areas consists of the English translation of Brodmann's Latin name followed by the number he assigned, e.g., agranular frontal area 6; the standard terms for monkey areas are in the format: area 6 of Brodmann-1909. He mapped a portion of areas limited to the banks of sulci, e.g., area 3 of Brodmann-1909 (Brodmann-1909) onto the adjacent, visible surface. This accounts for the fact that some areas appear larger on his surface map than on maps of other authors, e.g., area 3 of Vogts-1919. (Adapted from NeuroNames)" ;
  rdfs:subClassOf obo:UBERON_0002616 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#lithium-pilocarpine_model> a rdfs:Class ;
  rdfs:label "lithium-pilocarpine model" ;
  rdfs:subClassOf <https://bio.scai.fraunhofer.de/ontology/epilepsy#convulsant_drug_model> .

obo:OAE_0000002 a rdfs:Class ;
  rdfs:label "medical intervention" ;
  rdfs:comment "medical intervention is a planned process that has the goal of diagnosing, preventing or relieving illness or injury. " ;
  rdfs:subClassOf obo:OBI_0000011 .

obo:OBA_VT0005308 a rdfs:Class ;
  rdfs:label "blood ammonia amount" ;
  rdfs:comment "The amount of a ammonia when measured in blood." ;
  rdfs:subClassOf obo:CMO_0000063 .

obo:HP_0003394 a rdfs:Class ;
  rdfs:label "Muscle spasm" ;
  rdfs:comment "Sudden and involuntary contractions of one or more muscles." ;
  rdfs:subClassOf obo:HP_0011804 .

obo:HP_0025142 a rdfs:Class ;
  rdfs:label "Constitutional symptom" ;
  rdfs:comment "A symptom or manifestation indicating a systemic or general effect of a disease and that may affect the general well-being or status of an individual." ;
  rdfs:subClassOf obo:HP_0000118 .

obo:UBERON_0002420 a rdfs:Class ;
  rdfs:label "basal ganglion" ;
  rdfs:comment "An individual member of a collection of basal ganglia. Basal ganglia are subcortical masses of gray matter in the forebrain and midbrain that are richly interconnected and so viewed as a functional system. The nuclei usually included are the caudate nucleus (caudoputamen in rodents), putamen, globus pallidus, substantia nigra (pars compacta and pars reticulata) and the subthalamic nucleus. Some also include the nucleus accumbens and ventral pallidum[NIF,modified]." ;
  rdfs:seeAlso <http://www.case.edu/EpSO.owl#TelencephalonBasalGanglion> ;
  rdfs:subClassOf obo:UBERON_0003528 , obo:UBERON_0007245 .

obo:NBO_0000685 a rdfs:Class ;
  rdfs:label "continuous seizure" ;
  rdfs:subClassOf obo:SYMP_0000124 .

obo:MFOEM_000014 a rdfs:Class ;
  rdfs:label "rage" ;
  rdfs:seeAlso <https://www.epilepsy.com/connect/forums/family-friends/epilepsy-and-rage-episodes> ;
  rdfs:subClassOf obo:MFOEM_000009 .

obo:CMO_0000021 a rdfs:Class ;
  rdfs:label "body morphological measurement" ;
  rdfs:subClassOf obo:CMO_0000000 .

obo:HP_0011843 a rdfs:Class ;
  rdfs:label "Abnormality of skeletal physiology" ;
  rdfs:comment "An abnormality of the function of the skeletal system." ;
  rdfs:subClassOf obo:HP_0000924 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#structural_etiology> a rdfs:Class ;
  rdfs:label "structural etiology" ;
  rdfs:seeAlso <http://www.case.edu/EpSO.owl#StructuralCause> ;
  rdfs:subClassOf obo:NCIT_C16390 .

obo:DOID_10079 a rdfs:Class ;
  rdfs:label "cysticercosis" ;
  rdfs:comment "A taeniasis that results from ingestion of eggs or larvae of the Taenia solium tapeworm in undercooked pork or fecally contaminated food or water, which subsequently infect the central nervous system, heart, muscles, subcutaneous tissues, and eyes. Neurocysticercosis causes seizures, mental disturbances, focal neurologic deficits and intracerebral lesions." ;
  rdfs:subClassOf obo:DOID_331 .

obo:DOID_9281 a rdfs:Class ;
  rdfs:label "phenylketonuria" ;
  rdfs:comment "An amino acid metabolic disorder that is characterized by a mutation in the gene for the hepatic enzyme phenylalanine hydroxylase (PAH), rendering it nonfunctional." ;
  rdfs:seeAlso <https://www.epilepsy.com/learn/professionals/co-existing-disorders/metabolic-disorders/inborn-errors/phenylketonuria> ;
  rdfs:subClassOf obo:DOID_9252 .

obo:HP_0032058 a rdfs:Class ;
  rdfs:label "Focal cortical dysplasia type IIId" ;
  rdfs:comment "A subtype of focal cortical dysplasia type III that is characterized by altered architectural (cortical dyslamination, hypoplasia without six-layered structure) or cytoarchitectural composition (hypertrophic neurons) of the neocortex, which occur adjacent to other lesions acquired during early life (not included into FCD Type IIIa-c). These lesions comprise a large spectrum including traumatic brain injury, glial scarring after prenatal or perinatal ischemic injury or bleeding, and inflammatory or infectious diseases, i.e. Rasmussen encephalitis, limbic encephalitis, bacterial or viral infections." ;
  rdfs:seeAlso <http://www.case.edu/EpSO.owl#FocalCorticalDysplasiaTypeIIID> ;
  rdfs:subClassOf obo:HP_0032054 .

obo:BFO_0000023 a rdfs:Class ;
  rdfs:label "role" ;
  rdfs:subClassOf obo:BFO_0000017 .

obo:OMIT_0027688 a rdfs:Class ;
  rdfs:label "Neuroimaging" ;
  rdfs:subClassOf obo:ERO_0001312 .

obo:NCIT_C17204 a rdfs:Class ;
  rdfs:label "Computed Tomography" ;
  rdfs:comment "A method of examining structures within the body by scanning them with X rays and using a computer to construct a series of cross-sectional scans along a single axis." ;
  rdfs:subClassOf obo:ERO_0001312 .

obo:UBERON_0004111 a rdfs:Class ;
  rdfs:label "anatomical conduit" ;
  rdfs:comment "Any tube, opening or passage that connects two distinct anatomical spaces." ;
  rdfs:subClassOf obo:UBERON_0010000 .

obo:DOID_891 a rdfs:Class ;
  rdfs:label "progressive myoclonus epilepsy" ;
  rdfs:comment "A variable age at onset electroclinical syndrome characterised by a relentlessly progressive disease course until death." ;
  rdfs:subClassOf obo:MONDO_0100036 .

obo:SYMP_0000092 a rdfs:Class ;
  rdfs:label "skin lesion" ;
  rdfs:comment "Skin lesion is a skin and integumentary tissue symptom characterized as an abnormal change in structure of the skin that is especially circumscribed and well defined due to injury or disease." ;
  rdfs:subClassOf obo:SYMP_0000488 .

obo:OGMS_0000115 a rdfs:Class ;
  rdfs:label "physical therapy procedure" ;
  rdfs:comment "a therapeutic procedure that uses physical conditioning" ;
  rdfs:seeAlso <https://www.epilepsy.com/learn/diagnosis/you-and-your-healthcare-team/rehabilitation-therapists> ;
  rdfs:subClassOf obo:OGMS_0000112 .

obo:SYMP_0000458 a rdfs:Class ;
  rdfs:label "nausea" ;
  rdfs:comment "Nausea is a digestive system symptom characterized by an uneasy or unsettled feeling in the stomach together with an urge to vomit." ;
  rdfs:seeAlso <https://www.webmd.com/epilepsy/guide/abdominal-epilepsy-in-children-and-adults> ;
  rdfs:subClassOf obo:SYMP_0000459 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#febrile_seizure_model> a rdfs:Class ;
  rdfs:label "febrile seizure model" ;
  rdfs:subClassOf <https://bio.scai.fraunhofer.de/ontology/epilepsy#chemical_mutagenesis_derived_model> .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#infectious_cause_of_seizure> a rdfs:Class ;
  rdfs:label "infectious cause of seizure" ;
  rdfs:subClassOf obo:NCIT_C17103 .

obo:DOID_1289 a rdfs:Class ;
  rdfs:label "neurodegenerative disease" ;
  rdfs:comment "A central nervous system disease that results in the progressive deterioration of function or structure of neurons." ;
  rdfs:subClassOf obo:DOID_331 .

obo:CMO_0001232 a rdfs:Class ;
  rdfs:label "nervous system measurement" ;
  rdfs:subClassOf obo:CMO_0000000 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#epilepsy_classification> a rdfs:Class ;
  rdfs:label "epilepsy classification" ;
  rdfs:seeAlso <https://www.epilepsydiagnosis.org/epilepsy/epilepsy-classification-groupoverview.html> ;
  rdfs:subClassOf <https://bio.scai.fraunhofer.de/ontology/epilepsy#International_League_Against_Epilepsy_classification> .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#monomorphic_wave> a rdfs:Class ;
  rdfs:label "monomorphic wave" ;
  rdfs:seeAlso <https://www.medicine.mcgill.ca/physio/vlab/biomed_signals/eeg_n.htm> ;
  rdfs:subClassOf obo:OMIT_0027154 .

obo:HP_0000707 a rdfs:Class ;
  rdfs:label "Abnormality of the nervous system" ;
  rdfs:comment "An abnormality of the nervous system." ;
  rdfs:subClassOf obo:HP_0000118 .

obo:HP_0012443 a rdfs:Class ;
  rdfs:label "Abnormality of brain morphology" ;
  rdfs:comment "A structural abnormality of the brain, which has as its parts the forebrain, midbrain, and hindbrain." ;
  rdfs:subClassOf obo:HP_0002011 .

obo:NBO_0000643 a rdfs:Class ;
  rdfs:label "involuntary movement behavior phenotype" ;
  rdfs:comment "\"Observable characteristic of behavior related to movements that occur independent of planning.\" [NBO:GVG]" ;
  rdfs:subClassOf obo:NBO_0000568 .

obo:MP_0004924 a rdfs:Class ;
  rdfs:label "abnormal behavior" ;
  rdfs:comment "any anomaly in the actions, reactions, or performance of an organism in response to external or internal stimuli compared to controls" ;
  rdfs:subClassOf obo:SYMP_0019182 .

obo:MONDO_0015657 a rdfs:Class ;
  rdfs:label "inflammatory and autoimmune disease with epilepsy" ;
  rdfs:subClassOf obo:DOID_1826 .

obo:OGMS_0000057 a rdfs:Class ;
  rdfs:label "physical examination" ;
  rdfs:comment "A sequence of acts of observing and measuring qualities of a patient performed by a clinician; measurements may occur with and without elicitation." ;
  rdfs:subClassOf obo:OGMS_0000108 .

obo:UBERON_0034752 a rdfs:Class ;
  rdfs:label "secondary auditory cortex" ;
  rdfs:comment "The part of the auditory cortex that receive more diffuse input from the belt areas of the medial geniculate complex." ;
  rdfs:subClassOf obo:UBERON_0002616 .

obo:MONDO_0005697 a rdfs:Class ;
  rdfs:label "cerebral toxoplasmosis" ;
  rdfs:comment "Infections of the brain caused by the protozoan toxoplasma gondii that primarily arise in individuals with immunologic deficiency syndromes (see also aids-related opportunistic infections). The infection may involve the brain diffusely or form discrete abscesses. Clinical manifestations include seizures, altered mentation, headache, focal neurologic deficits, and intracranial hypertension. (From Joynt, Clinical Neurology, 1998, Ch27, pp41-3)" ;
  rdfs:subClassOf <https://bio.scai.fraunhofer.de/ontology/epilepsy#infectious_etiology> .

obo:MONDO_0024291 a rdfs:Class ;
  rdfs:label "vascular malformation" ;
  rdfs:comment "A non-neoplastic disorder that is the result of defects of vascular morphogenesis." ;
  rdfs:seeAlso <http://www.case.edu/EpSO.owl#VascularMalformation> ;
  rdfs:subClassOf <https://bio.scai.fraunhofer.de/ontology/epilepsy#structural_etiology> .

obo:NCIT_C154766 a rdfs:Class ;
  rdfs:label "Gamma-Aminobutyric Acid Measurement" ;
  rdfs:comment "The determination of the amount of gamma-aminobutyric acid present in a sample." ;
  rdfs:subClassOf obo:OBA_0000116 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#autoimmune_seizure> a rdfs:Class ;
  rdfs:label "autoimmune seizure" ;
  rdfs:subClassOf obo:SYMP_0000124 .

obo:GO_0008150 a rdfs:Class ;
  rdfs:label "biological_process" ;
  rdfs:comment "A biological process represents a specific objective that the organism is genetically programmed to achieve. Biological processes are often described by their outcome or ending state, e.g., the biological process of cell division results in the creation of two daughter cells (a divided cell) from a single parent cell. A biological process is accomplished by a particular set of molecular functions carried out by specific gene products (or macromolecular complexes), often in a highly regulated manner and in a particular temporal sequence." ;
  rdfs:subClassOf obo:BFO_0000015 .

obo:HP_0011161 a rdfs:Class ;
  rdfs:label "Olfactory auras" ;
  rdfs:comment "Auras with sensation of odor, usually disagreeable." ;
  rdfs:subClassOf obo:HP_0011157 .

obo:NCIT_C99020 a rdfs:Class ;
  rdfs:label "Porencephalic Cyst" ;
  rdfs:comment "A congenital or acquired cystic cavity within the cerebral hemisphere." ;
  rdfs:subClassOf <https://bio.scai.fraunhofer.de/ontology/epilepsy#structural_etiology> .

obo:MONDO_0100036 a rdfs:Class ;
  rdfs:label "variable age onset epilepsy" ;
  rdfs:comment "An epilepsy syndrome that has an onset during variable ages and stages of life." ;
  rdfs:subClassOf obo:MONDO_0015650 .

obo:DOID_0060041 a rdfs:Class ;
  rdfs:label "autism spectrum disorder" ;
  rdfs:comment "A pervasive developmental disorder that is a spectrum of psychological conditions. The disease has_symptom widespread abnormalities of social interactions and communication, has_symptom severely restricted interests and has_symptom highly repetitive behavior." ;
  rdfs:seeAlso <http://www.case.edu/EpSO.owl#AutismSpectrumDisorder> ;
  rdfs:subClassOf obo:DOID_0060040 .

obo:GO_0048609 a rdfs:Class ;
  rdfs:label "multicellular organismal reproductive process" ;
  rdfs:comment "The process, occurring above the cellular level, that is pertinent to the reproductive function of a multicellular organism. This includes the integrated processes at the level of tissues and organs." ;
  rdfs:subClassOf obo:GO_0022414 .

obo:SYMP_0000891 a rdfs:Class ;
  rdfs:label "musculoskeletal system symptom" ;
  rdfs:subClassOf obo:SYMP_0000462 .

obo:MP_0003929 a rdfs:Class ;
  rdfs:label "decreased heart rate variability" ;
  rdfs:comment "reduced variation of beat-to-beat intervals of the heart that occurs in conjunction with the respiratory cycle" ;
  rdfs:subClassOf obo:MP_0004122 .

obo:DOID_10935 a rdfs:Class ;
  rdfs:label "dissociative disorder" ;
  rdfs:comment "A disease of mental health in which the normally well-integrated functions of memory, identity, perception, or consciousness are separated (dissociated)." ;
  rdfs:subClassOf obo:NCIT_C35470 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#interictal_dysphoric_disorder> a rdfs:Class ;
  rdfs:label "interictal dysphoric disorder" ;
  rdfs:subClassOf obo:MONDO_0002025 .

<https://bio.scai.fraunhofer.de/ontology/0000504> a rdfs:Class ;
  rdfs:label "seizure event" ;
  rdfs:subClassOf obo:NCIT_C25499 .

obo:NCIT_C15986 a rdfs:Class ;
  rdfs:label "Pharmacotherapy" ;
  rdfs:comment "Treatment of disease through the use of drugs." ;
  rdfs:subClassOf obo:OGMS_0000112 .

obo:UBERON_0019303 a rdfs:Class ;
  rdfs:label "occipital sulcus" ;
  rdfs:subClassOf obo:UBERON_0013118 .

obo:HP_0025373 a rdfs:Class ;
  rdfs:label "Interictal EEG abnormality" ;
  rdfs:comment "Interictal refers to a period of time between epileptic seizures. Electroencephalographic (EEG) patterns are important in the differential diagnosis of epilepsy, and the EEG is almost always abnormal during a seizure. Some persons with seizures may show EEG abnormalities between seizures, while others do not. In some cases, multiple interictal EEGs must be recorded before an abnormality is observed. In most cases the electrographic pattern of seizure onset is completely different from the activity recorded during interictal discharge." ;
  rdfs:seeAlso <http://www.case.edu/EpSO.owl#InterIctalPattern> ;
  rdfs:subClassOf obo:HP_0002353 .

obo:MONDO_0021637 a rdfs:Class ;
  rdfs:label "low grade glioma" ;
  rdfs:comment "A grade I or grade II glioma arising from the central nervous system. This category includes pilocytic astrocytoma, diffuse astrocytoma, subependymal giant cell astrocytoma, ependymoma, oligodendroglioma, oligoastrocytoma, and angiocentric glioma." ;
  rdfs:seeAlso <http://www.case.edu/EpSO.owl#LowGradeGlioma> ;
  rdfs:subClassOf obo:MONDO_0021042 .

obo:UBERON_0003876 a rdfs:Class ;
  rdfs:label "hippocampal field" ;
  rdfs:comment "a part or parts of the hippocampus that have a particular function" ;
  rdfs:subClassOf obo:UBERON_0002616 .

obo:CMO_0002242 a rdfs:Class ;
  rdfs:label "blood creatine kinase activity level" ;
  rdfs:subClassOf obo:CMO_0000064 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#extensor_spasm> a rdfs:Class ;
  rdfs:label "extensor spasm" ;
  rdfs:subClassOf obo:HP_0003394 .

obo:ERO_0001312 a rdfs:Class ;
  rdfs:label "imaging technique" ;
  rdfs:comment "A technique used to create a representation or reproduction of an object's outward form; especially a visual representation (i.e., the formation of an image)." ;
  rdfs:subClassOf obo:ERO_0000007 .

obo:NBO_0000159 a rdfs:Class ;
  rdfs:label "rapid eye movement sleep" ;
  rdfs:seeAlso <https://n.neurology.org/content/90/15_Supplement/P3.278> , <http://www.case.edu/EpSO.owl#SleepOnsetRapidEyeMovement> ;
  rdfs:subClassOf <https://bio.scai.fraunhofer.de/ontology/epilepsy#special_pattern> .

<https://bio.scai.fraunhofer.de/ontology/0000516> a rdfs:Class ;
  rdfs:label "multi-contact electrode" ;
  rdfs:subClassOf obo:NCIT_C49936 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#alpha_variant> a rdfs:Class ;
  rdfs:label "alpha variant" ;
  rdfs:seeAlso <https://neurology.mhmedical.com/content.aspx?bookid=1042&sectionid=59078723#1101635347> , <http://www.case.edu/EpSO.owl#AlphaVariant> ;
  rdfs:subClassOf <https://bio.scai.fraunhofer.de/ontology/epilepsy#rhythmic_benign_variant> .

obo:UBERON_0000454 a rdfs:Class ;
  rdfs:label "cerebral subcortex" ;
  rdfs:comment "The layer located below the cerebral cortex that includes the forebrain, midbrain and hindbrain." ;
  rdfs:seeAlso <http://www.case.edu/EpSO.owl#SubcorticalTelecephalonSegment> ;
  rdfs:subClassOf obo:UBERON_0000064 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#tottering_mouse> a rdfs:Class ;
  rdfs:label "tottering mouse" ;
  rdfs:subClassOf <https://bio.scai.fraunhofer.de/ontology/epilepsy#absence_seizure_model> .

obo:MONDO_0100029 a rdfs:Class ;
  rdfs:label "antibody mediated epilepsy" ;
  rdfs:comment "An immune epilepsy where the underlying cause is antibody mediated." ;
  rdfs:seeAlso <https://www.epilepsydiagnosis.org/aetiology/antibody-mediated-overview.html> ;
  rdfs:subClassOf <https://bio.scai.fraunhofer.de/ontology/epilepsy#immune_etiology> .

obo:HP_0000826 a rdfs:Class ;
  rdfs:label "Precocious puberty" ;
  rdfs:comment "The onset of secondary sexual characteristics before a normal age. Although it is difficult to define normal age ranges because of the marked variation with which puberty begins in normal children, precocious puberty can be defined as the onset of puberty before the age of 8 years in girls or 9 years in boys." ;
  rdfs:seeAlso <http://www.case.edu/EpSO.owl#PrecociousPuberty> ;
  rdfs:subClassOf obo:HP_0100000 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#metallic_taste_hallucination> a rdfs:Class ;
  rdfs:label "metallic taste hallucination" ;
  rdfs:subClassOf obo:NCIT_C118177 .

obo:NCBITaxon_6204 a rdfs:Class ;
  rdfs:label "Taenia solium" ;
  rdfs:subClassOf obo:NCBITaxon_6157 .

obo:OMIT_0008479 a rdfs:Class ;
  rdfs:label "Intelligence Tests" ;
  rdfs:subClassOf obo:NCIT_C20993 .

obo:HP_0002170 a rdfs:Class ;
  rdfs:label "Intracranial hemorrhage" ;
  rdfs:comment "Hemorrhage occurring within the skull." ;
  rdfs:subClassOf obo:HP_0011029 , obo:HP_0100659 .

obo:DOID_1510 a rdfs:Class ;
  rdfs:label "personality disorder" ;
  rdfs:comment "A disease of mental health that involve long-term patterns of thoughts and behaviors that cause serious problems with relationships and work." ;
  rdfs:subClassOf obo:DOID_150 .

obo:MP_0005176 a rdfs:Class ;
  rdfs:label "eyelids fail to open" ;
  rdfs:comment "eyes remain shut when eyelids are expected to be open" ;
  rdfs:subClassOf obo:MP_0004874 .

obo:NCIT_C61377 a rdfs:Class ;
  rdfs:label "Network" ;
  rdfs:comment "An interconnected system of things or people." ;
  rdfs:subClassOf obo:BFO_0000031 .

obo:UBERON_0034751 a rdfs:Class ;
  rdfs:label "primary auditory cortex" ;
  rdfs:comment "The part of the auditory cortex that is located on the superior temporal gyrus in the temporal lobe and receives point-to-point input from the ventral division of the medial geniculate complex." ;
  rdfs:subClassOf obo:UBERON_0002616 .

obo:HP_0000317 a rdfs:Class ;
  rdfs:label "Facial myokymia" ;
  rdfs:comment "Facial myokymia is a fine fibrillary activity of one or more muscles innervated by the facial nerve (the seventh cranial nerve)." ;
  rdfs:subClassOf obo:HP_0000301 , obo:HP_0002411 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#left_frontal_astrocytoma> a rdfs:Class ;
  rdfs:label "left frontal astrocytoma" ;
  rdfs:seeAlso <http://www.case.edu/EpSO.owl#LeftFrontalAstrocytoma> , <https://rarediseases.org/rare-diseases/anaplastic-astrocytoma/> ;
  rdfs:subClassOf obo:DOID_3069 .

obo:HP_0003011 a rdfs:Class ;
  rdfs:label "Abnormality of the musculature" ;
  rdfs:comment "Abnormality originating in one or more muscles, i.e., of the set of muscles of body." ;
  rdfs:subClassOf obo:HP_0000118 .

obo:NCIT_C26920 a rdfs:Class ;
  rdfs:label "Encephalopathy" ;
  rdfs:comment "A functional and/or structural disorder of the brain caused by diseases (e.g. liver disease, kidney disease), medications, chemicals, and injuries." ;
  rdfs:subClassOf obo:DOID_936 .

obo:DOID_1319 a rdfs:Class ;
  rdfs:label "brain cancer" ;
  rdfs:comment "A central nervous system cancer that is characterized by the growth of abnormal cells in the tissues of the brain." ;
  rdfs:subClassOf obo:DOID_936 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#temporo_parietal_epilepsy> a rdfs:Class ;
  rdfs:label "temporo parietal epilepsy" ;
  rdfs:seeAlso <http://www.case.edu/EpSO.owl#TemporoParietalEpilepsy> ;
  rdfs:subClassOf obo:DOID_1826 .

obo:MONDO_0009187 a rdfs:Class ;
  rdfs:label "celiac disease-epilepsy-cerebral calcification syndrome" ;
  rdfs:comment "Celiac disease, epilepsy and cerebral calcification syndrome (CEC) is a rare disorder characterized by the combination of auto-immune intestinal disease, epileptic seizures and cerebral calcifications." ;
  rdfs:subClassOf obo:MONDO_0100029 .

obo:NBO_0000119 a rdfs:Class ;
  rdfs:label "impulsive behavior" ;
  rdfs:comment "\"A behavior that occur quickly without control, planning, or consideration of the consequences of that behavior.\" [NBO:GVG]" ;
  rdfs:subClassOf obo:NBO_0000313 .

obo:SYMP_0000510 a rdfs:Class ;
  rdfs:label "pallor" ;
  rdfs:comment "Pallor is a skin and integumentary tissue symptom characterized as a deficiency of color especially of the face." ;
  rdfs:subClassOf obo:SYMP_0000488 .

obo:PW_0000844 a rdfs:Class ;
  rdfs:label "glutamate signaling pathway" ;
  rdfs:comment "Glutamate signaling via the ionotropic AMPA or NMDA and several metabotropic receptors plays important roles in the modulation of synaptic plasticity, long term depression or potentiation, and in learning and memory." ;
  rdfs:subClassOf obo:GO_0007165 .

obo:DOID_2843 a rdfs:Class ;
  rdfs:label "long QT syndrome" ;
  rdfs:comment "An autosomal genetic disease that is characterized by delayed repolarization of the heart following a heartbeat increases the risk of episodes of torsade de pointes (TDP, a form of irregular heartbeat that originates from the ventricles)." ;
  rdfs:seeAlso <https://www.epilepsydiagnosis.org/epilepsy-imitators.html#longqt> ;
  rdfs:subClassOf obo:HP_0001279 .

obo:BFO_0000016 a rdfs:Class ;
  rdfs:label "disposition" ;
  rdfs:subClassOf obo:BFO_0000017 .

obo:UBERON_0006104 a rdfs:Class ;
  rdfs:label "Brodmann (1909) area 36" ;
  rdfs:comment "Ectorhinal area 36 is a subdivision of the cytoarchitecturally defined temporal region of cerebral cortex. With its medial boundary corresponding approximately to the rhinal sulcus it is located primarily in the fusiform gyrus. Cytoarchitecturally it is bounded laterally and caudally by the inferior temporal area 20, medially by the perirhinal area 35 and rostrally by the temporopolar area 38 (H) (Brodmann-1909). Together with Brodmann area 35, it comprises the perirhinal cortex." ;
  rdfs:subClassOf obo:UBERON_0013529 .

<https://bio.scai.fraunhofer.de/ontology/0000400> a rdfs:Class ;
  rdfs:label "risk factor TM_BIN" ;
  rdfs:comment "The 'risk factor TM_BIN' concept enables a compilation of diverse concepts that are related to risk factors in Epilepsy via the Axiome 'isRiskFactorFor some epilepsy'.  Thus enables the adaptation of the ontology for text mining purposes for Epilepsy related information retrieval and information extraction." .

obo:ERO_0001285 a rdfs:Class ;
  rdfs:label "organismal assay" ;
  rdfs:comment "An assay that generates data about the physical characteristics,  physological functions, or behavior of organisms or viruses." ;
  rdfs:subClassOf obo:OBI_0000070 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#seizure_based_on_hemispheric_lateralization> a rdfs:Class ;
  rdfs:label "seizure based on hemispheric lateralization" ;
  rdfs:subClassOf obo:HP_0007359 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#tantrum_and_rage_reaction> a rdfs:Class ;
  rdfs:label "tantrum and rage reaction" ;
  rdfs:subClassOf obo:NCIT_C35470 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#14Hz_and_6Hz_positive_spike> a rdfs:Class ;
  rdfs:label "14Hz and 6Hz positive spike" ;
  rdfs:seeAlso <https://emedicine.medscape.com/article/1140563-overview#a1> , <http://www.case.edu/EpSO.owl#Fourteen-SixHertzPositiveBurst> ;
  rdfs:subClassOf <https://bio.scai.fraunhofer.de/ontology/epilepsy#epileptiform_benign_variant> .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#focal_cognitive_seizure_with_dissociation> a rdfs:Class ;
  rdfs:label "focal cognitive seizure with dissociation" ;
  rdfs:subClassOf <https://bio.scai.fraunhofer.de/ontology/epilepsy#focal_cognitive_seizure> .

obo:NCBITaxon_7742 a rdfs:Class ;
  rdfs:label "Vertebrata <vertebrates>" ;
  rdfs:subClassOf obo:NCBITaxon_2759 .

obo:UBERON_0013556 a rdfs:Class ;
  rdfs:label "Brodmann (1909) area 25" ;
  rdfs:comment "Brodmann area 25 (BA25) is an area in the cerebral cortex of the brain and delineated based on its cytoarchitectonic characteristics. It is also called the subgenual area or area subgenualis. It is the 25th 'Brodmann area' defined by Korbinian Brodmann (thus its name). BA25 is located in the cingulate region as a narrow band in the caudal portion of the subcallosal area adjacent to the paraterminal gyrus. The posterior parolfactory sulcus separates the paraterminal gyrus from BA25. Rostrally it is bound by the prefrontal area 11 of Brodmann." ;
  rdfs:subClassOf obo:UBERON_0013529 .

obo:HP_0010927 a rdfs:Class ;
  rdfs:label "Abnormal blood inorganic cation concentration" ;
  rdfs:comment "An abnormality of divalent inorganic cation homeostasis." ;
  rdfs:subClassOf obo:HP_0010929 .

obo:PW_0000001 a rdfs:Class ;
  rdfs:label "pathway" ;
  rdfs:comment "A pathway is a set of inter-connected  reactions and interactions whose delineation and scope are used as a model for exploring and studying, describing and understanding the working of and relationships between biomolecules within a context." ;
  rdfs:subClassOf obo:GO_0009987 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#language_functional_magnetic_resonance_imaging> a rdfs:Class ;
  rdfs:label "language functional magnetic resonance imaging" ;
  rdfs:seeAlso <https://www.frontiersin.org/articles/10.3389/fnhum.2019.00183/full> ;
  rdfs:subClassOf obo:ERO_0002178 .

obo:UBERON_0000477 a rdfs:Class ;
  rdfs:label "anatomical cluster" ;
  rdfs:comment "Anatomical group that has its parts adjacent to one another." ;
  rdfs:subClassOf obo:UBERON_0001062 .

obo:DOID_9455 a rdfs:Class ;
  rdfs:label "lipid storage disease" ;
  rdfs:comment "A lysosomal storage disease that involves the accumulation of harmful amounts of lipids (fats) in some of the body's cells and tissues." ;
  rdfs:subClassOf obo:DOID_3211 .

obo:DOID_0050951 a rdfs:Class ;
  rdfs:label "hereditary ataxia" ;
  rdfs:comment "A neurodegenerative disease that is characterized by slowly progressive incoordination of gait and often associated with poor coordination of hands, speech, and eye movements." ;
  rdfs:subClassOf obo:DOID_1289 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#electrodecrement> a rdfs:Class ;
  rdfs:label "electrodecrement" ;
  rdfs:seeAlso <http://www.case.edu/EpSO.owl#Electrodecrement> ;
  rdfs:subClassOf obo:HP_0025373 .

obo:IAO_0000030 a rdfs:Class ;
  rdfs:label "information content entity" ;
  rdfs:comment "An information content entity is an entity that is generically dependent on some artifact and stands in relation of aboutness to some entity" ;
  rdfs:subClassOf obo:BFO_0000031 .

obo:UBERON_0002298 a rdfs:Class ;
  rdfs:label "brainstem" ;
  rdfs:comment "Stalk-like part of the brain that includes amongst its parts the medulla oblongata of the hindbrain and the tegmentum of the midbrain[ZFA,MP,generalized]." ;
  rdfs:subClassOf obo:UBERON_0002616 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#immediate_and_early_post_cerebral_insult_seizure> a rdfs:Class ;
  rdfs:label "immediate and early post cerebral insult seizure" ;
  rdfs:subClassOf obo:SYMP_0000124 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#sexual_seizure> a rdfs:Class ;
  rdfs:label "sexual seizure" ;
  rdfs:seeAlso <https://www.psychologytoday.com/us/blog/sex-in-the-brain/202001/what-happens-during-sexual-seizure> , <http://www.case.edu/EpSO.owl#SexualSeizure> ;
  rdfs:subClassOf obo:SYMP_0000124 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#myoclonic_absence_status_epilepticus> a rdfs:Class ;
  rdfs:label "myoclonic absence status epilepticus" ;
  rdfs:subClassOf <https://bio.scai.fraunhofer.de/ontology/epilepsy#generalized_non_convulsive_status_epilepticus_without_coma> .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#lamotrigine_resistant_kindled_model> a rdfs:Class ;
  rdfs:label "lamotrigine resistant kindled model" ;
  rdfs:subClassOf <https://bio.scai.fraunhofer.de/ontology/epilepsy#pharmacoresistant_epilepsy_model> .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#after_discharge> a rdfs:Class ;
  rdfs:label "afterdischarges model" ;
  rdfs:subClassOf obo:NCIT_C19021 .

obo:HP_0002282 a rdfs:Class ;
  rdfs:label "Gray matter heterotopia" ;
  rdfs:comment "Heterotopia or neuronal heterotopia are macroscopic clusters of misplaced neurons (gray matter), most often situated along the ventricular walls or within the subcortical white matter." ;
  rdfs:subClassOf obo:NCIT_C84834 .

obo:DOID_1932 a rdfs:Class ;
  rdfs:label "Angelman syndrome" ;
  rdfs:comment "A syndrome that is characterized by delayed development, intellectual disability, severe speech impairment, and problems with movement and balance." ;
  rdfs:seeAlso <https://www.ilae.org/guidelines/definition-and-classification> ;
  rdfs:subClassOf obo:MONDO_0019040 .

obo:NCIT_C38047 a rdfs:Class ;
  rdfs:label "Curative Surgery" ;
  rdfs:comment "Surgery which cures disease." ;
  rdfs:subClassOf obo:NCIT_C161601 .

obo:HP_0011028 a rdfs:Class ;
  rdfs:label "Abnormality of blood circulation" ;
  rdfs:comment "An abnormality of blood circulation." ;
  rdfs:subClassOf obo:HP_0011025 .

obo:UBERON_0000466 a rdfs:Class ;
  rdfs:label "immaterial anatomical entity" ;
  rdfs:comment "Anatomical entity that has no mass." ;
  rdfs:subClassOf obo:UBERON_0001062 .

obo:UBERON_0013553 a rdfs:Class ;
  rdfs:label "Brodmann (1909) area 22" ;
  rdfs:comment "Brodmann area 22 is one of Brodmann's cytologically defined regions of the brain. It is involved in auditory processing." ;
  rdfs:subClassOf obo:UBERON_0013529 .

obo:UBERON_0000064 a rdfs:Class ;
  rdfs:label "organ part" ;
  rdfs:comment "A multicellular structure that is a part of an organ." ;
  rdfs:subClassOf obo:UBERON_0010000 .

obo:PATO_0001995 a rdfs:Class ;
  rdfs:label "organismal quality" ;
  rdfs:comment "A quality that inheres in an entire organism or part of an organism." ;
  rdfs:subClassOf obo:PATO_0001241 .

obo:SYMP_0000016 a rdfs:Class ;
  rdfs:label "confusion" ;
  rdfs:comment "Confusion is a neurological and physiological symptom characterized by a disturbance of consciousness characterized by inability to engage in orderly thought or by lack of power to distinguish, choose, or act decisively." ;
  rdfs:subClassOf obo:SYMP_0000410 .

obo:GO_0007165 a rdfs:Class ;
  rdfs:label "signal transduction" ;
  rdfs:comment "The cellular process in which a signal is conveyed to trigger a change in the activity or state of a cell. Signal transduction begins with reception of a signal (e.g. a ligand binding to a receptor or receptor activation by a stimulus such as light), or for signal transduction in the absence of ligand, signal-withdrawal or the activity of a constitutively active receptor. Signal transduction ends with regulation of a downstream cellular process, e.g. regulation of transcription or regulation of a metabolic process. Signal transduction covers signaling from receptors located on the surface of the cell and signaling via molecules located within the cell. For signaling between cells, signal transduction is restricted to events at and within the receiving cell." ;
  rdfs:subClassOf obo:GO_0009987 .

obo:HP_0025015 a rdfs:Class ;
  rdfs:label "Abnormal vascular morphology" ;
  rdfs:subClassOf obo:HP_0002597 .

obo:UBERON_0002661 a rdfs:Class ;
  rdfs:label "superior frontal gyrus" ;
  rdfs:comment "Component of the frontal lobe, lateral aspect. The rostral boundary is the first appearance of the superior frontal sulcus whereas the caudal boundary is the midpoint of the paracentral sulcus on the \"inflated\" surface. The medial and lateral boundaries are the medial aspect of the frontal lobe and the superior frontal sulcus respectively (Christine Fennema-Notestine)." ;
  rdfs:subClassOf obo:UBERON_0015593 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#genetic_etiology> a rdfs:Class ;
  rdfs:label "genetic etiology" ;
  rdfs:seeAlso <http://www.case.edu/EpSO.owl#GeneticDefect> ;
  rdfs:subClassOf obo:NCIT_C16390 .

obo:NCIT_C102117 a rdfs:Class ;
  rdfs:label "European Quality of Life Five Dimension Five Level Scale Questionnaire" ;
  rdfs:comment "A standardized rating scale which is used as a measure of health outcome. This instrument is a descriptive system consisting of 5 dimensions: mobility, self-care, usual activity, pain/discomfort, and anxiety/depression. Each dimension has 5 levels ranging from no problem to extreme problem or incapable, which are assessed by the patient." ;
  rdfs:subClassOf obo:NCIT_C91105 .

obo:MP_0004122 a rdfs:Class ;
  rdfs:label "abnormal sinus arrhythmia" ;
  rdfs:comment "any anomaly in the normal phenomenon of mild acceleration and slowing of the heart rate that occurs during the respiratory cycle" ;
  rdfs:subClassOf obo:MP_0001629 .

obo:MONDO_0100030 a rdfs:Class ;
  rdfs:label "adolescent/adult-onset epilepsy syndrome" ;
  rdfs:comment "An epilepsy syndrome that has an onset during the adolescent or adult stage of life." ;
  rdfs:seeAlso <https://www.epilepsydiagnosis.org/syndrome/epilepsy-syndrome-groupoverview.html> ;
  rdfs:subClassOf obo:MONDO_0015650 .

obo:HP_0000549 a rdfs:Class ;
  rdfs:label "Abnormal conjugate eye movement" ;
  rdfs:comment "Any deviation from the normal motor coordination of the eyes that allows for bilateral fixation on a single object." ;
  rdfs:subClassOf obo:HP_0000496 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#K_complex> a rdfs:Class ;
  rdfs:label "K complex" ;
  rdfs:seeAlso <https://emedicine.medscape.com/article/1139332-overview#a1> ;
  rdfs:subClassOf <https://bio.scai.fraunhofer.de/ontology/epilepsy#normal_EEG_pattern> .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#negative_motor_seizure> a rdfs:Class ;
  rdfs:label "negative motor seizure" ;
  rdfs:subClassOf obo:SYMP_0000124 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#temporal_intermittent_rythmic_delta_activity> a rdfs:Class ;
  rdfs:label "temporal intermittent rythmic delta activity" ;
  rdfs:seeAlso <http://www.case.edu/EpSO.owl#TemporalIntermittentRythmicDeltaActivity> ;
  rdfs:subClassOf obo:HP_0010845 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#ictal_pattern> a rdfs:Class ;
  rdfs:label "ictal pattern" ;
  rdfs:seeAlso <http://www.case.edu/EpSO.owl#IctalPattern> ;
  rdfs:subClassOf obo:HP_0011198 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#excessive_fast_pattern> a rdfs:Class ;
  rdfs:label "excessive fast pattern" ;
  rdfs:seeAlso <http://www.case.edu/EpSO.owl#ExcessiveFastPattern> ;
  rdfs:subClassOf <https://bio.scai.fraunhofer.de/ontology/epilepsy#special_pattern> .

obo:HP_0000315 a rdfs:Class ;
  rdfs:label "Abnormality of the orbital region" ;
  rdfs:subClassOf obo:HP_0000271 .

obo:DOID_11294 a rdfs:Class ;
  rdfs:label "arteriovenous malformation" ;
  rdfs:comment "A hemangioma that is characterized by a configuration of blood vessels that shunts arterial blood directly into veins by bypassing the capillary system." ;
  rdfs:subClassOf obo:MONDO_0024291 .

obo:NBO_0000681 a rdfs:Class ;
  rdfs:label "benign rolandic epilepsy" ;
  rdfs:comment "\"Benign rolandic epilepsy is characterized by either simple partial seizures involving the mouth and face or generalized tonic-clonic seizures.\" [wikipedia:http\\://en.wikipedia.org/wiki/Rolandic_epilepsy]" ;
  rdfs:subClassOf obo:DOID_1826 .

obo:DOID_0080015 a rdfs:Class ;
  rdfs:label "physical disorder" ;
  rdfs:comment "A disease that has_material_basis_in a genetic abnormality, error with embryonic development, infection or compromised intrauterine environment." ;
  rdfs:subClassOf obo:DOID_4 .

obo:DOID_0060108 a rdfs:Class ;
  rdfs:label "brain glioma" ;
  rdfs:comment "A brain cancer that has_material_basis_in glial cells." ;
  rdfs:seeAlso <http://www.case.edu/EpSO.owl#LowGradeGlioma> ;
  rdfs:subClassOf obo:MONDO_0021042 .

obo:PW_0000595 a rdfs:Class ;
  rdfs:label "phosphatidylinositol 3-kinase signaling pathway" ;
  rdfs:comment "Phosphatidylinositol kinases represent a family of lipid kinases that phosphorylate the 3' position of the inositol ring in target substrates. They are grouped into three classes: class I further subdivided into subclass A and B, class II and class III. By far the best known and characterized is class I, particularly IA that signals downstream of receptor tyrosine kinases and engages the Akt family of kinases." ;
  rdfs:subClassOf obo:GO_0007165 .

obo:SYMP_0000408 a rdfs:Class ;
  rdfs:label "cataplexy" ;
  rdfs:comment "Cataplexy is a muscle symptom characterized by a sudden loss of muscle control with retention of clear consciousness that follows a strong emotional stimulus (as elation, surprise, or anger) and is a characteristic symptom of narcolepsy." ;
  rdfs:seeAlso <http://www.case.edu/EpSO.owl#Cataplexy> ;
  rdfs:subClassOf obo:SYMP_0000183 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#focal_autonomic_seizure_with_piloerection> a rdfs:Class ;
  rdfs:label "focal autonomic seizure with piloerection" ;
  rdfs:seeAlso <https://www.epilepsydiagnosis.org/seizure/autonomic-overview.html> , <http://epilepsyontario.org/about-epilepsy/types-of-seizures/simple-partial-seizures/> , <https://www.neurology-asia.org/articles/neuroasia-2018-23(2)-163.pdf> ;
  rdfs:subClassOf obo:HP_0011154 .

obo:DOID_1921 a rdfs:Class ;
  rdfs:label "Klinefelter's syndrome" ;
  rdfs:comment "No OMIM mapping, confirmed by DO. [LS]." ;
  rdfs:subClassOf obo:MONDO_0019040 .

obo:HP_0004936 a rdfs:Class ;
  rdfs:label "Venous thrombosis" ;
  rdfs:comment "Formation of a blood clot (thrombus) inside a vein, causing the obstruction of blood flow." ;
  rdfs:subClassOf obo:HP_0001977 .

obo:UBERON_0002695 a rdfs:Class ;
  rdfs:label "parieto-occipital sulcus" ;
  rdfs:comment "Only a small part of the Parietooccipital Fissure (or parieto-occipital sulcus) is seen on the lateral surface of the hemisphere, its chief part being on the medial surface. The lateral part of the parietooccipital fissure (Fig. 726) is situated about 5 cm. in front of the occipital pole of the hemisphere, and measures about 1.25 cm. in length. The medial part of the parietooccipital fissure (Fig. 727) runs downward and forward as a deep cleft on the medial surface of the hemisphere, and joins the calcarine fissure below and behind the posterior end of the corpus callosum. In most cases it contains a submerged gyrus. [WP,unvetted]." ;
  rdfs:subClassOf obo:UBERON_0008334 .

obo:NCBITaxon_9443 a rdfs:Class ;
  rdfs:label "Primates" ;
  rdfs:subClassOf obo:NCBITaxon_40674 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#delta_coma> a rdfs:Class ;
  rdfs:label "delta coma" ;
  rdfs:seeAlso <http://www.case.edu/EpSO.owl#DeltaComa> ;
  rdfs:subClassOf <https://bio.scai.fraunhofer.de/ontology/epilepsy#special_pattern> .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#hypnogogic_jerk> a rdfs:Class ;
  rdfs:label "hypnogogic jerk" ;
  rdfs:seeAlso <http://purl.bioontology.org/ontology/SNOMEDCT/443438009> ;
  rdfs:subClassOf obo:DOID_535 .

obo:GO_0007186 a rdfs:Class ;
  rdfs:label "G protein-coupled receptor signaling pathway" ;
  rdfs:comment "A series of molecular signals that proceeds with an activated receptor promoting the exchange of GDP for GTP on the alpha-subunit of an associated heterotrimeric G-protein complex. The GTP-bound activated alpha-G-protein then dissociates from the beta- and gamma-subunits to further transmit the signal within the cell. The pathway begins with receptor-ligand interaction, or for basal GPCR signaling the pathway begins with the receptor activating its G protein in the absence of an agonist, and ends with regulation of a downstream cellular process, e.g. transcription.  The pathway can start from the plasma membrane, Golgi or nuclear membrane." ;
  rdfs:subClassOf obo:GO_0007165 .

obo:MONDO_0019486 a rdfs:Class ;
  rdfs:label "myoclonic epilepsy of infancy" ;
  rdfs:subClassOf obo:MONDO_0100022 .

obo:SYMP_0000089 a rdfs:Class ;
  rdfs:label "meningoencephalitis" ;
  rdfs:comment "Meningoencephalitis is a nervous system symptom characterized as an inflammation of the brain and meninges." ;
  rdfs:subClassOf <https://bio.scai.fraunhofer.de/ontology/epilepsy#infectious_etiology> .

obo:NCIT_C41328 a rdfs:Class ;
  rdfs:label "Electrocardiographic Finding" ;
  rdfs:comment "Graphic representation and categorization of the electrical vectors produced by the depolarization and repolarization of myocardial tissue." ;
  rdfs:subClassOf obo:OGMS_0000014 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#non-invasive_preoperative_evaluation> a rdfs:Class ;
  rdfs:label "non-invasive preoperative evaluation" ;
  rdfs:subClassOf obo:NCIT_C139982 .

<https://bio.scai.fraunhofer.de/ontology/0000513> a rdfs:Class ;
  rdfs:label "inter-ictal" ;
  rdfs:subClassOf obo:PATO_0001912 .

obo:UBERON_0006481 a rdfs:Class ;
  rdfs:label "Brodmann (1909) area 44" ;
  rdfs:comment "Brodmann area 44, or BA44, is part of the frontal cortex in the human brain. Situated just anterior to premotor cortex and on the lateral surface, inferior to BA9. This area is also known as pars opercularis (of the inferior frontal gyrus), and it refers to a subdivision of the cytoarchitecturally defined frontal region of cerebral cortex. In the human it corresponds approximately to the opercular part of inferior frontal gyrus (H). Thus, it is bounded caudally by the inferior precentral sulcus (H) and rostrally by the anterior ascending limb of lateral sulcus (H). It surrounds the diagonal sulcus (H). In the depth of the lateral sulcus it borders on the insula. Cytoarchitectonically it is bounded caudally and dorsally by the agranular frontal area 6, dorsally by the granular frontal area 9 and rostrally by the triangular area 45 (Brodmann-1909)." ;
  rdfs:subClassOf obo:UBERON_0013529 .

obo:HP_0032054 a rdfs:Class ;
  rdfs:label "Focal cortical dysplasia type III" ;
  rdfs:comment "A type of focal cortical dysplasia that is characterized by cortical lamination abnormalities associated with a principal lesion, usually adjacent to or affecting the same cortical area/lobe." ;
  rdfs:seeAlso <http://www.case.edu/EpSO.owl#FocalCorticalDysplasiaTypeIII> ;
  rdfs:subClassOf obo:HP_0032046 .

obo:UBERON_0006479 a rdfs:Class ;
  rdfs:label "Brodmann (1909) area 38" ;
  rdfs:comment "Brodmann area 38, also BA38 or temporopolar area 38 (H), is part of the temporal cortex in the human brain. BA 38 is at the anterior end of the temporal lobe, known as the temporal pole. BA38 is a subdivision of the cytoarchitecturally defined temporal region of cerebral cortex. It is located primarily in the most rostral portions of the superior temporal gyrus and the middle temporal gyrus. Cytoarchitecturally it is bounded caudally by the inferior temporal area 20, the middle temporal area 21, the superior temporal area 22 and the ectorhinal area 36 (Brodmann-1909). Cytoarchitectonic and chemoarchitectonic studies find that it contains at least seven subareas, one of which, TG, is unique to humans. 'The functional significance of this area TG is not known, but it may bind complex, highly processed perceptual inputs to visceral emotional responses.' This area is among the earliest affected by Alzheimer's disease and the earliest involved at the start of temporal lobe seizures. [" ;
  rdfs:subClassOf obo:UBERON_0013529 .

obo:DOID_630 a rdfs:Class ;
  rdfs:label "genetic disease" ;
  rdfs:comment "A disease that has_material_basis_in genetic variations in the human genome." ;
  rdfs:subClassOf obo:DOID_4 .

<https://bio.scai.fraunhofer.de/ontology/0000508> a rdfs:Class ;
  rdfs:label "functional connectivity measure" ;
  rdfs:subClassOf obo:IAO_0000027 .

obo:RS_0000765 a rdfs:Class ;
  rdfs:label "inbred strain" ;
  rdfs:comment "Inbred Strains are produced by brother x sister mating for 20 or more consecutive generations, and individuals of the strain can be traced to a single ancestral pair at the 20th or subsequent generation." ;
  rdfs:subClassOf obo:RS_0000457 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#focal_autonomic_seizure_with_epigastric_sensation_or_with_nausea_/_vomiting> a rdfs:Class ;
  rdfs:label "focal autonomic seizure with epigastric sensation or with nausea / vomiting" ;
  rdfs:subClassOf obo:HP_0011154 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#rapid_eye_movement_atonia> a rdfs:Class ;
  rdfs:label "rapid eye movement atonia" ;
  rdfs:subClassOf obo:NBO_0000419 .

obo:MONDO_0020476 a rdfs:Class ;
  rdfs:label "mesial temporal lobe epilepsy with hippocampal sclerosis" ;
  rdfs:comment "Mesial temporal lobe epilepsy with hippocampal sclerosis is a rare epilepsy syndrome defined by seizures originating in limbic areas of the mesial temporal lobe, particularly in the hippocampus, amygdala, and in the parahippocampal gyrus and its connections, and hippocampal sclerosis, usually unilateral or assymetric. It is frequently associated with an initial precipitating event, such as febrile seizures, hypoxia, intracranial infection or head trauma, most often occurring in the first five years of life, followed by a latent period without seizures. Typical seizures consist of a characteristic aura that is frequently a rising epigastric sensation associated with emotional disturbances, illusions, and autonomic symptoms (widened pupils, palpitations), progressive impairment of consciousness, oro-alimentary automatisms (lip smacking, chewing, licking, tooth grinding), behavioral arrest, head deviation, dystonic postures, hand and verbal automatisms. Seizures are followed by postictal dysfunction. Initially, seizures are easily controlled with antiepileptic drugs, later they frequently become refractory and associated with progressive behavioral changes and memory deficits." ;
  rdfs:subClassOf obo:DOID_1826 .

obo:HP_0032047 a rdfs:Class ;
  rdfs:label "Focal cortical dysplasia type I" ;
  rdfs:comment "A type of focal cortical dysplasia that is characterized by abnormal cortical layering." ;
  rdfs:seeAlso <http://www.case.edu/EpSO.owl#FocalCorticalDysplasiaTypeI> ;
  rdfs:subClassOf obo:HP_0032046 .

obo:DOID_0014667 a rdfs:Class ;
  rdfs:label "disease of metabolism" ;
  rdfs:comment "A disease that involving errors in metabolic processes of building or degradation of molecules." ;
  rdfs:seeAlso <https://www.epilepsy.com/learn/professionals/co-existing-disorders/metabolic-disorders> ;
  rdfs:subClassOf obo:DOID_4 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#hypoxic_and_ischemic_injury> a rdfs:Class ;
  rdfs:label "hypoxic and ischemic injury" ;
  rdfs:seeAlso <http://www.case.edu/EpSO.owl#HypoxicIschemicInjury> ;
  rdfs:subClassOf <https://bio.scai.fraunhofer.de/ontology/epilepsy#hypoxic-ischemic> .

obo:UBERON_0001384 a rdfs:Class ;
  rdfs:label "primary motor cortex" ;
  rdfs:comment "The part of the cerebral cortex that receives projections from the motor thalamus and which projects to motor neurons in the brainstem and spinal cord. The motor cortex corresponds to Brodmann's area 4 (MM). The primary motor cortex, or M1, is located on the precentral gyrus and on the anterior paracentral lobule on the medial surface of the brain. Of the three motor cortex areas, stimulation of the primary motor cortex requires the least amount of electrical current to elicit a movement. http://neuroscience.uth.tmc.edu/s3/chapter03.html" ;
  rdfs:subClassOf obo:UBERON_0002616 .

obo:MFOMD_0000154 a rdfs:Class ;
  rdfs:label "anhedonia" ;
  rdfs:comment """Is defined as the inability to experience pleasure from activities usually found enjoyable, e.g. exercise, hobbies, music, sexual activities or social interactions.


http://en.wikipedia.org/wiki/Anhedonia""" ;
  rdfs:subClassOf obo:MFOMD_0000024 .

obo:CMO_0000028 a rdfs:Class ;
  rdfs:label "blood protein measurement" ;
  rdfs:subClassOf obo:CMO_0000023 .

obo:DOID_1682 a rdfs:Class ;
  rdfs:label "congenital heart disease" ;
  rdfs:comment "OMIM mapping confirmed by DO. [SN]." ;
  rdfs:seeAlso <https://www.epilepsy.com/learn/professionals/co-existing-disorders/cardiac-disorders/congenital-heart-disease> ;
  rdfs:subClassOf obo:DOID_114 .

obo:MF_0000020 a rdfs:Class ;
  rdfs:label "mental process" ;
  rdfs:comment "A mental process is a bodily process that is of a type such that it can of itself be conscious. Examples include thinking, feeling pain, remembering and emotion as occurrent experiences. " ;
  rdfs:subClassOf obo:OGMS_0000060 .

obo:HP_0011198 a rdfs:Class ;
  rdfs:label "EEG with generalized epileptiform discharges" ;
  rdfs:comment "EEG discharges recorded on the entire scalp typically seen in persons with epilepsy." ;
  rdfs:seeAlso <http://www.case.edu/EpSO.owl#EpileptiformPattern> ;
  rdfs:subClassOf obo:HP_0011182 .

obo:DOID_0060244 a rdfs:Class ;
  rdfs:label "specific language impairment" ;
  rdfs:comment "A language disorder characterized by difficulty in language acquisition despite otherwise normal development and in the absence of any obvious explanatory factors." ;
  rdfs:subClassOf obo:DOID_93 .

obo:SYMP_0000610 a rdfs:Class ;
  rdfs:label "dizziness" ;
  rdfs:comment "Dizziness is a neurological and physiological symptom characterized by a sensation of unsteadiness accompanied by a feeling of movement within the head." ;
  rdfs:subClassOf obo:SYMP_0000410 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#pelopsia> a rdfs:Class ;
  rdfs:label "pelopsia" ;
  rdfs:seeAlso <http://www.case.edu/EpSO.owl#Pelopsia> ;
  rdfs:subClassOf obo:HP_0000504 .

obo:HP_0010852 a rdfs:Class ;
  rdfs:label "EEG with photoparoxysmal response" ;
  rdfs:comment "EEG abnormalities (epileptiform discharges) evoked by flashing lights or black and white striped patterns." ;
  rdfs:seeAlso <http://www.case.edu/EpSO.owl#PhotoparoxysmalResponse> ;
  rdfs:subClassOf obo:HP_0002353 .

obo:OGMS_0000032 a rdfs:Class ;
  rdfs:label "homeostasis" ;
  rdfs:subClassOf obo:BFO_0000016 .

obo:BFO_0000001 a rdfs:Class ;
  rdfs:label "entity" .

obo:DOID_594 a rdfs:Class ;
  rdfs:label "panic disorder" ;
  rdfs:comment "An anxiety disorder that is characterized by unexpected and repeated episodes of intense fear accompanied by physical symptoms that may include chest pain, heart palpitations, shortness of breath, dizziness, or abdominal distress." ;
  rdfs:subClassOf obo:DOID_2030 .

obo:OMIT_0019508 a rdfs:Class ;
  rdfs:label "Craniofacial Abnormalities" ;
  rdfs:seeAlso <https://medlineplus.gov/craniofacialabnormalities.html> ;
  rdfs:subClassOf obo:DOID_17 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#basal_temporal_epilepsy> a rdfs:Class ;
  rdfs:label "basal temporal epilepsy" ;
  rdfs:seeAlso <http://www.case.edu/EpSO.owl#BasalTemporalEpilepsy> ;
  rdfs:subClassOf obo:DOID_3328 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#non-epileptic_seizure> a rdfs:Class ;
  rdfs:label "non-epileptic seizure" ;
  rdfs:subClassOf obo:NCIT_C35470 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#lateral_/_neocortical_temporal_lobe_seizure> a rdfs:Class ;
  rdfs:label "lateral / neocortical temporal lobe seizure" ;
  rdfs:seeAlso <http://www.medlink.com/article/neocortical_temporal_lobe_seizures> ;
  rdfs:subClassOf <https://bio.scai.fraunhofer.de/ontology/epilepsy#temporal_lobe_seizure> .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#seizure_based_on_lobar_localization> a rdfs:Class ;
  rdfs:label "seizure based on lobar localization" ;
  rdfs:seeAlso <https://www.epilepsydiagnosis.org/seizure/focal-seizure-overview.html#> ;
  rdfs:subClassOf obo:HP_0007359 .

obo:UBERON_0001018 a rdfs:Class ;
  rdfs:label "axon tract" ;
  rdfs:comment "A group of axons linking two or more neuropils and having a common origin, termination[FBbt]." ;
  rdfs:subClassOf obo:UBERON_0000122 , obo:UBERON_0011215 .

obo:BFO_0000026 a rdfs:Class ;
  rdfs:label "one-dimensional spatial region" ;
  rdfs:subClassOf obo:BFO_0000006 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#malaria-related_seizure> a rdfs:Class ;
  rdfs:label "malaria-related seizure" ;
  rdfs:subClassOf <https://bio.scai.fraunhofer.de/ontology/epilepsy#infectious_cause_of_seizure> .

obo:ERO_0001286 a rdfs:Class ;
  rdfs:label "nucleic acid assay" ;
  rdfs:comment "A molecular assay that generates data about the presence, abundance, structure, function, or activity of nucleic acids." ;
  rdfs:subClassOf obo:ERO_0000833 .

obo:DOID_0060407 a rdfs:Class ;
  rdfs:label "chromosome 18q deletion syndrome" ;
  rdfs:subClassOf obo:MONDO_0019040 .

obo:NCBITaxon_9606 a rdfs:Class ;
  rdfs:label "Homo sapiens" ;
  rdfs:subClassOf obo:NCBITaxon_9443 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#brain_junction> a rdfs:Class ;
  rdfs:label "brain junction" ;
  rdfs:subClassOf obo:UBERON_0000956 .

obo:MONDO_0021193 a rdfs:Class ;
  rdfs:label "neuroepithelial neoplasm" ;
  rdfs:comment "A neoplasm of the nervous system that arises from the neuroepithelial tissues. Representative examples include astrocytic tumors, oligodendroglial tumors, ependymal tumors, and primitive neuroectodermal tumors." ;
  rdfs:subClassOf obo:MONDO_0021248 .

obo:SYMP_0000226 a rdfs:Class ;
  rdfs:label "atrial fibrillation" ;
  rdfs:comment "A cardiac fibrillation consisting of a very rapid uncoordinated contractions of the atria of the heart resulting in a lack of synchronism between heartbeat and pulse beat." ;
  rdfs:subClassOf obo:SYMP_0000898 .

obo:MONDO_0100025 a rdfs:Class ;
  rdfs:label "epilepsy of infancy with migrating focal seizures" ;
  rdfs:comment "This syndrome is characterized by onset of refractory focal seizures in the first year of life, with associated severe encephalopathy. Focal seizures arise independently in both hemispheres and can migrate from one cortical region to another randomly but consecutively in the same seizure. Seizures are often prolonged with episodes of status epilepticus. Prognosis is poor with severe neurological disability and reduced life expectancy, although a milder evolution has been reported in a few children." ;
  rdfs:subClassOf obo:MONDO_0100022 .

obo:HP_0002902 a rdfs:Class ;
  rdfs:label "Hyponatremia" ;
  rdfs:comment "An abnormally decreased sodium concentration in the blood." ;
  rdfs:seeAlso <https://www.epilepsy.com/learn/professionals/co-existing-disorders/metabolic-disorders/electrolyte-abnormalities/hyponatremia> ;
  rdfs:subClassOf obo:HP_0010931 .

obo:DOID_4724 a rdfs:Class ;
  rdfs:label "brain edema" ;
  rdfs:comment "A brain disease that is characterized by excess accumulation of fluid in the intracellular and/or extracellular spaces of the brain, has_symptom nausea, has_symptom vomiting, has_symptom blurred vision, has_symptom seizure, has_symptom coma." ;
  rdfs:subClassOf obo:DOID_936 .

obo:RS_0004742 a rdfs:Class ;
  rdfs:label "W/Lnne" ;
  rdfs:subClassOf obo:RS_0000765 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#self-limited_neonatal_seizure_and_self-limited_familial_neonatal_epilepsy> a rdfs:Class ;
  rdfs:label "self-limited neonatal seizure and self-limited familial neonatal epilepsy" ;
  rdfs:subClassOf obo:MONDO_0100022 .

obo:PW_0000103 a rdfs:Class ;
  rdfs:label "transport pathway" ;
  rdfs:comment "A pathway that mediates or facilitates the movement of biochemical material, organic and inorganic substances and/or drugs." ;
  rdfs:subClassOf obo:PW_0000001 .

obo:NCIT_C17103 a rdfs:Class ;
  rdfs:label "Risk Factor" ;
  rdfs:comment "Any aspect of an individual's life, behavior, an environmental exposure, or an inborn or inherited characteristic that increases the likelihood of a disease, condition or injury." ;
  rdfs:subClassOf obo:BFO_0000016 .

obo:CMO_0001356 a rdfs:Class ;
  rdfs:label "red blood cell measurement" ;
  rdfs:seeAlso <https://www.webmd.com/epilepsy/guide/epilepsy-blood-test> ;
  rdfs:subClassOf obo:CMO_0000036 .

obo:UBERON_0002947 a rdfs:Class ;
  rdfs:label "frontal operculum" ;
  rdfs:comment "Portion of frontal lobe that overlaps the insular cortex (adapted from Wikipedia)" ;
  rdfs:seeAlso <http://www.case.edu/EpSO.owl#FrontalOperculum> ;
  rdfs:subClassOf obo:UBERON_0002616 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#mixed_spasm> a rdfs:Class ;
  rdfs:label "mixed spasm" ;
  rdfs:subClassOf obo:HP_0003394 .

obo:MONDO_0018215 a rdfs:Class ;
  rdfs:label "paraneoplastic neurologic syndrome" ;
  rdfs:comment "A paraneoplastic syndrome that involves the nervous system." ;
  rdfs:subClassOf obo:DOID_936 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#organotypic_slice_cultures> a rdfs:Class ;
  rdfs:label "organotypic slice cultures" ;
  rdfs:subClassOf obo:NCIT_C19146 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#focal_cognitive_seizure_with_hallucination> a rdfs:Class ;
  rdfs:label "focal cognitive seizure with hallucination" ;
  rdfs:subClassOf <https://bio.scai.fraunhofer.de/ontology/epilepsy#focal_cognitive_seizure> .

obo:MONDO_0024883 a rdfs:Class ;
  rdfs:label "metastatic neoplasm" ;
  rdfs:comment "A tumor that has spread from its original (primary) site of growth to another site, close to or distant from the primary site. Metastasis is characteristic of advanced malignancies, but in rare instances can be seen in neoplasms lacking malignant morphology." ;
  rdfs:seeAlso <http://www.case.edu/EpSO.owl#MetastaticTumor> ;
  rdfs:subClassOf obo:MONDO_0024882 .

obo:SYMP_0000231 a rdfs:Class ;
  rdfs:label "bradycardia" ;
  rdfs:comment "Bradycardia is a cardiovascular system symptom consisting of a relatively slow heart action whether physiological or pathological." ;
  rdfs:subClassOf obo:SYMP_0000287 .

obo:DOID_655 a rdfs:Class ;
  rdfs:label "inherited metabolic disorder" ;
  rdfs:comment "A disease of metabolism that is characterized by enzyme deficiency or accumulation of enzymes or toxins which interfere with normal function due to inherited enzyme abnormality." ;
  rdfs:subClassOf obo:DOID_0014667 , obo:DOID_630 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#focal_cognitive_seizure_with_dyscalculia/acalculia> a rdfs:Class ;
  rdfs:label "focal cognitive seizure with dyscalculia/acalculia" ;
  rdfs:subClassOf <https://bio.scai.fraunhofer.de/ontology/epilepsy#focal_cognitive_seizure> .

obo:DOID_11257 a rdfs:Class ;
  rdfs:label "social phobia" ;
  rdfs:comment "A phobic disorder that involves social anxiety occurring only in specific public or social situations, interactions with others or being evaluated or scrutinized by other people." ;
  rdfs:subClassOf obo:DOID_591 .

obo:HP_0011150 a rdfs:Class ;
  rdfs:label "Myoclonic absence" ;
  rdfs:comment "Rhythmic myoclonic jerks of the shoulders and arms with tonic abduction that results in progressive lifting of the arms during the seizure. The myoclonic jerks are typically bilateral but may be unilateral or asymmetric. Perioral myoclonias and rhythmic jerks of the head and legs may occur. Seizures last 10-60 seconds and typically occur daily. Level of awareness varies from complete loss of awareness to retained awareness." ;
  rdfs:seeAlso <https://www.epilepsydiagnosis.org/seizure/awsf-myoclonic-absence-overview.html> ;
  rdfs:subClassOf <https://bio.scai.fraunhofer.de/ontology/epilepsy#generalized_non-motor_onset_seizure> .

obo:HP_0010549 a rdfs:Class ;
  rdfs:label "Weakness due to upper motor neuron dysfunction" ;
  rdfs:comment "Paralysis of voluntary muscles means loss of contraction due to interruption of one or more motor pathways from the brain to the muscle fibers. Although the word paralysis is often used interchangeably to mean either complete or partial loss of muscle strength, it is preferable to use paralysis or plegia for complete or severe loss of muscle strength, and paresis for partial or slight loss. Paralysis due to lesions of the principle motor tracts is related to a lesion in the corticospinal, corticobulbar or brainstem descending (subcorticospinal) neurons." ;
  rdfs:subClassOf obo:HP_0002493 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#temporo-parieto-occipital_junction> a rdfs:Class ;
  rdfs:label "temporo-parieto-occipital junction" ;
  rdfs:subClassOf <https://bio.scai.fraunhofer.de/ontology/epilepsy#brain_junction> .

obo:OGMS_0000024 a rdfs:Class ;
  rdfs:label "sign" ;
  rdfs:comment "A quality of a patient, a material entity that is part of a patient, or a processual entity that a patient participates in, any one of which is observed in a physical examination and is deemed by the clinician to be of clinical significance." ;
  rdfs:subClassOf obo:BFO_0000001 .

obo:NBO_0000499 a rdfs:Class ;
  rdfs:label "NREM parasomnia" ;
  rdfs:comment "\"A type of parasomnia that occurs during NREM sleep.\" [NBO:GVG]" ;
  rdfs:subClassOf obo:NBO_0000419 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#occipital_pole_epilepsy> a rdfs:Class ;
  rdfs:label "occipital pole epilepsy" ;
  rdfs:seeAlso <http://www.case.edu/EpSO.owl#OccipitalPoleEpilepsy> ;
  rdfs:subClassOf <https://bio.scai.fraunhofer.de/ontology/epilepsy#lateral_occipital_epilepsy> .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#focal_motor_seizure_with_dystonia> a rdfs:Class ;
  rdfs:label "focal motor seizure with dystonia" ;
  rdfs:subClassOf obo:HP_0011153 .

obo:HP_0004327 a rdfs:Class ;
  rdfs:label "Abnormal vitreous humor morphology" ;
  rdfs:comment "Any structural anomaly of the vitreous body." ;
  rdfs:subClassOf obo:HP_0004329 .

obo:UBERON_0013550 a rdfs:Class ;
  rdfs:label "Brodmann (1909) area 19" ;
  rdfs:comment "Brodmann area 19, or BA19, is part of the occipital lobe cortex in the human brain. Along with area 18, it comprises the extrastriate (or peristriate) cortex. In normally-sighted humans, extrastriate cortex is a visual association area, with feature-extracting, shape recognition, attentional, and multimodal integrating functions. This area is also known as peristriate area 19, and it refers to a subdivision of the cytoarchitecturally defined occipital region of cerebral cortex. In the human it is located in parts of the lingual gyrus, the cuneus, the lateral occipital gyrus (H) and the superior occipital gyrus (H) of the occipital lobe where it is bounded approximately by the parieto-occipital sulcus. Cytoarchitecturally it is bounded on one side by the parastriate area 18 which it surrounds. Rostrally it is bounded by the angular area 39 (H) and the occipitotemporal area 37 (H) (Brodmann-1909)." ;
  rdfs:subClassOf obo:UBERON_0013529 .

obo:UBERON_0009834 a rdfs:Class ;
  rdfs:label "dorsolateral prefrontal cortex" ;
  rdfs:comment "The dorsolateral prefrontal cortex (DL-PFC or DLPFC), according to a more restricted definition, is roughly equivalent to Brodmann areas 9 and 46.[1] According to a broader definition DL-PFC consists of the lateral portions of Brodmann areas 9 - 12, of areas 45, 46, and the superior part of area 47.[2] These regions mainly receive their blood supply from the middle cerebral artery. With respect to neurotransmitter systems, there is evidence that dopamine plays a particularly important role in DL-PFC.[2]DL-PFC is connected to the orbitofrontal cortex, and to a variety of brain areas, which include the thalamus, parts of the basal ganglia (the dorsal caudate nucleus), the hippocampus, and primary and secondary association areas of neocortex, including posterior temporal, parietal, and occipital areas" ;
  rdfs:subClassOf obo:UBERON_0002616 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#special_seizure> a rdfs:Class ;
  rdfs:label "special seizure" ;
  rdfs:seeAlso <http://www.case.edu/EpSO.owl#SpecialSeizure> ;
  rdfs:subClassOf obo:SYMP_0000124 .

obo:HP_0010531 a rdfs:Class ;
  rdfs:label "Spinal myoclonus" ;
  rdfs:comment "Spinal myoclonus is generally due to a tumor, infection, injury, or degenerative process of the spinal cord, and is characterized by involuntary rhythmic muscle contractions, usually at a rate of more than one per second. Myoclonus occurs synchronously in several muscles and can be increased in severity and frequency by fatigue or stress, but is usually unaffected by sensory stimuli. Spinal myoclonus ceases during sleep or anesthesia." ;
  rdfs:subClassOf obo:NCIT_C69023 .

obo:SYMP_0000480 a rdfs:Class ;
  rdfs:label "nervous system symptom" ;
  rdfs:subClassOf obo:SYMP_0000462 .

obo:DOID_13268 a rdfs:Class ;
  rdfs:label "porphyria" ;
  rdfs:comment "An inherited metabolic disorder that involves certain enzymes in the heme bio-synthetic pathway resulting in the overproduction and accumulation of the porphyrins." ;
  rdfs:subClassOf obo:DOID_655 .

obo:UBERON_0006473 a rdfs:Class ;
  rdfs:label "Brodmann (1909) area 18" ;
  rdfs:comment "." ;
  rdfs:subClassOf obo:UBERON_0013529 .

obo:ERO_0000007 a rdfs:Class ;
  rdfs:label "technique" ;
  rdfs:comment "A technique is a planned process used to accomplish a specific activity or task." ;
  rdfs:subClassOf obo:OBI_0000011 .

obo:UBERON_0001946 a rdfs:Class ;
  rdfs:label "inferior colliculus" ;
  rdfs:comment "Part of the midbrain tectum, consisting of paired predominantly gray matter elevations on the dorsal aspect of the midbrain, located caudal to the superior colliculus, dorsal to the periaqueductal gray of the cerebral aqueduct and rostral to the cerebellum. According to Neuronames, the inferior colliculus comprises the central, pericentral and external nucleus and two predominantly white matter structures, the brachium of the inferior colliculus and the commissure of the inferior colliculus (MM)." ;
  rdfs:subClassOf obo:UBERON_0002616 .

obo:HP_0003781 a rdfs:Class ;
  rdfs:label "Excessive salivation" ;
  rdfs:comment "Excessive production of saliva." ;
  rdfs:subClassOf obo:HP_0100755 .

obo:OBI_0400147 a rdfs:Class ;
  rdfs:label "microarray" ;
  rdfs:comment "A processed material that is made to be used in an analyte assay. It consists of a physical immobilisation matrix in which substances that bind the analyte are placed in regular spatial position." ;
  rdfs:subClassOf obo:OBI_0001865 .

obo:DOID_11201 a rdfs:Class ;
  rdfs:label "parathyroid gland disease" ;
  rdfs:comment "An endocrine system disease that is located_in the parathyroid gland." ;
  rdfs:subClassOf obo:DOID_28 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#metabolic_imaging> a rdfs:Class ;
  rdfs:label "metabolic imaging" ;
  rdfs:subClassOf obo:OMIT_0027689 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#channel_blocker-induced_seizure> a rdfs:Class ;
  rdfs:label "channel blocker-induced seizure" ;
  rdfs:subClassOf <https://bio.scai.fraunhofer.de/ontology/epilepsy#toxic_cause_of_seizure> .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#complex_visual_hallucination> a rdfs:Class ;
  rdfs:label "complex visual hallucination" ;
  rdfs:seeAlso <http://www.case.edu/EpSO.owl#ComplexVisualHallucination> ;
  rdfs:subClassOf obo:NBO_0000609 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#unclassified_seizure_onset> a rdfs:Class ;
  rdfs:label "unclassified seizure onset" ;
  rdfs:subClassOf <https://bio.scai.fraunhofer.de/ontology/epilepsy#unknown_onset_seizure> .

obo:GO_0003012 a rdfs:Class ;
  rdfs:label "muscle system process" ;
  rdfs:comment "A organ system process carried out at the level of a muscle. Muscle tissue is composed of contractile cells or fibers." ;
  rdfs:subClassOf obo:GO_0003008 .

obo:SYMP_0000508 a rdfs:Class ;
  rdfs:label "aphasia" ;
  rdfs:comment "Aphasia is a nervous system symptom characterized by a loss or impairment of the power to use or comprehend words usually resulting from brain damage." ;
  rdfs:subClassOf obo:SYMP_0000480 .

obo:FMA_242176 a rdfs:Class ;
  rdfs:label "Broca's area" ;
  rdfs:seeAlso <https://www.epilepsydiagnosis.org/seizure/frontal-lobe-overview.html> ;
  rdfs:subClassOf obo:UBERON_0000956 .

obo:UBERON_0002688 a rdfs:Class ;
  rdfs:label "supramarginal gyrus" ;
  rdfs:comment "Component of the parietal lobe. The first coronal slice between the superior temporal gyrus and the postcentral gyrus where the supramarginal gyrus appears was the rostral boundary whereas the slice where the supramarginal gyrus becomes continuous with the superior parietal gyrus was the caudal boundary. The medial and lateral boundaries were the lateral banks of the intraparietal sulcus and the medial banks of the lateral fissure and/or the superior temporal gyrus respectively (Christine Fennema-Notestine)." ;
  rdfs:subClassOf obo:UBERON_0000200 .

obo:HP_0000598 a rdfs:Class ;
  rdfs:label "Abnormality of the ear" ;
  rdfs:comment "An abnormality of the ear." ;
  rdfs:subClassOf obo:HP_0000118 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#right_fronto_parietal_abscess> a rdfs:Class ;
  rdfs:label "right fronto parietal abscess" ;
  rdfs:seeAlso <http://www.case.edu/EpSO.owl#RightFrontoParietalAbcess> ;
  rdfs:subClassOf obo:HP_0030049 .

obo:DOID_6713 a rdfs:Class ;
  rdfs:label "cerebrovascular disease" ;
  rdfs:comment "An vascular disease that is characterized by dysfunction of the blood vessels supplying the brain." ;
  rdfs:seeAlso <http://www.case.edu/EpSO.owl#CerebrovascularDisease> ;
  rdfs:subClassOf obo:DOID_178 , obo:DOID_936 .

obo:DOID_1574 a rdfs:Class ;
  rdfs:label "alcohol use disorder" ;
  rdfs:comment "A substance abuse that involves the recurring use of alcoholic beverages despite negative consequences." ;
  rdfs:seeAlso <http://www.case.edu/EpSO.owl#AlcoholAbuse> ;
  rdfs:subClassOf obo:DOID_302 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#theta_coma> a rdfs:Class ;
  rdfs:label "theta coma" ;
  rdfs:seeAlso <http://www.case.edu/EpSO.owl#ThetaComa> ;
  rdfs:subClassOf <https://bio.scai.fraunhofer.de/ontology/epilepsy#special_pattern> .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#high_potassium_slice_model> a rdfs:Class ;
  rdfs:label "high potassium slice model" ;
  rdfs:subClassOf obo:NCIT_C19146 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#hippocampal_sclerosis> a rdfs:Class ;
  rdfs:label "hippocampal sclerosis" ;
  rdfs:seeAlso <http://www.case.edu/EpSO.owl#MesialTemporalSclerosis> ;
  rdfs:subClassOf <https://bio.scai.fraunhofer.de/ontology/epilepsy#structural_etiology> .

obo:HP_0032053 a rdfs:Class ;
  rdfs:label "Focal cortical dysplasia type IIb" ;
  rdfs:comment "A subtype of focal cortical dysplasia type II that is characterized by dysmorphic neurons (significantly enlarged with accumulation of neurofilament proteins) and balloon cells." ;
  rdfs:seeAlso <http://www.case.edu/EpSO.owl#FocalCorticalDysplasiaTypeIIB> ;
  rdfs:subClassOf obo:HP_0032051 .

obo:HP_0002017 a rdfs:Class ;
  rdfs:label "Nausea and vomiting" ;
  rdfs:subClassOf obo:HP_0011458 .

obo:DOID_863 a rdfs:Class ;
  rdfs:label "nervous system disease" ;
  rdfs:comment "A disease of anatomical entity that is located_in the central nervous system or located_in the peripheral nervous system." ;
  rdfs:subClassOf obo:DOID_7 .

obo:GO_0003008 a rdfs:Class ;
  rdfs:label "system process" ;
  rdfs:comment "A multicellular organismal process carried out by any of the organs or tissues in an organ system. An organ system is a regularly interacting or interdependent group of organs or tissues that work together to carry out a biological objective." ;
  rdfs:subClassOf obo:GO_0032501 .

obo:UBERON_0002286 a rdfs:Class ;
  rdfs:label "third ventricle" ;
  rdfs:comment "Part of the ventricular system of the brain, forming a single large cavity in the midline of the diencephalon; it is continuous with the lateral ventricles through the interventricular foramen and the fourth ventricle through the cerebral aqueduct. (Maryann Martone)" ;
  rdfs:subClassOf obo:UBERON_0004086 .

obo:HP_0010783 a rdfs:Class ;
  rdfs:label "Erythema" ;
  rdfs:comment "Redness of the skin, caused by hyperemia of the capillaries in the lower layers of the skin." ;
  rdfs:subClassOf obo:HP_0011276 .

obo:MONDO_0008206 a rdfs:Class ;
  rdfs:label "benign paroxysmal tonic upgaze of childhood with ataxia" ;
  rdfs:comment "Benign paroxysmal tonic upgaze of childhood with ataxia is a rare paroxysmal movement disorder characterized by episodes of sustained, conjugate, upward deviation of the eyes and down beating saccades in attempted downgaze (with preserved horizontal eye movements) which is accompanied by ataxic symptomatology (unsteady gait, lack of balance and movement coordination disturbances) in an otherwise healthy individual. Bilateral vertical nystagmus is associated. Symptoms generally disappear spontaneously within 1-2 years after onset." ;
  rdfs:subClassOf obo:MONDO_0017657 .

obo:SYMP_0000473 a rdfs:Class ;
  rdfs:label "nutrition, metabolism, and development symptom" ;
  rdfs:subClassOf obo:SYMP_0000462 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#chronic_spontaneous_limbic_seizure_model> a rdfs:Class ;
  rdfs:label "chronic spontaneous limbic seizure model" ;
  rdfs:subClassOf obo:NCIT_C19021 .

obo:BFO_0000004 a rdfs:Class ;
  rdfs:label "independent continuant" ;
  rdfs:comment "b is an independent continuant = Def. b is a continuant which is such that there is no c and no t such that b s-depends_on c at t. (axiom label in BFO2 Reference: [017-002])" ;
  rdfs:subClassOf obo:BFO_0000002 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#benign_paroxysmal_vertigo> a rdfs:Class ;
  rdfs:label "benign paroxysmal vertigo" ;
  rdfs:subClassOf <https://bio.scai.fraunhofer.de/ontology/epilepsy#migraine_associated_disorder> .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#anterior_cingulate_epilepsy> a rdfs:Class ;
  rdfs:label "anterior cingulate epilepsy" ;
  rdfs:seeAlso <http://www.case.edu/EpSO.owl#AnteriorCingulateEpilepsy> ;
  rdfs:subClassOf <https://bio.scai.fraunhofer.de/ontology/epilepsy#cingulate_epilepsy> .

obo:SYMP_0000099 a rdfs:Class ;
  rdfs:label "pain" ;
  rdfs:comment "A sensation perception where there is an unpleasant sensation that usually indicates the body is threatened or damaged. The sensation may be sharp or dull, short-lived or chronic, intermittent or continual, confined to one area or spread over the entire body." ;
  rdfs:subClassOf obo:SYMP_0000892 .

obo:BFO_0000146 a rdfs:Class ;
  rdfs:label "two-dimensional continuant fiat boundary" ;
  rdfs:subClassOf obo:BFO_0000140 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#borborygmi> a rdfs:Class ;
  rdfs:label "borborygmi" ;
  rdfs:subClassOf obo:SYMP_0000459 .

obo:HP_0002315 a rdfs:Class ;
  rdfs:label "Headache" ;
  rdfs:comment "Cephalgia, or pain sensed in various parts of the head, not confined to the area of distribution of any nerve." ;
  rdfs:seeAlso <https://www.epilepsy.com/learn/about-epilepsy-basics/what-happens-during-seizure> ;
  rdfs:subClassOf obo:HP_0012638 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#worthiness> a rdfs:Class ;
  rdfs:label "worthiness" ;
  rdfs:seeAlso <http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2011000600009> ;
  rdfs:subClassOf obo:MFOEM_000001 .

obo:NCBITaxon_100937 a rdfs:Class ;
  rdfs:label "Papio papio" ;
  rdfs:subClassOf obo:NCBITaxon_9443 .

obo:GO_0016055 a rdfs:Class ;
  rdfs:label "Wnt signaling pathway" ;
  rdfs:comment "The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell and ending with a change in cell state." ;
  rdfs:subClassOf obo:GO_0007165 .

obo:SYMP_0000020 a rdfs:Class ;
  rdfs:label "dehydration" ;
  rdfs:comment "Dehydration is a nutrition, metabolism, and development symptom characterized by an abnormal depletion of body fluids." ;
  rdfs:seeAlso <https://www.epilepsy.com/learn/about-epilepsy-basics/what-are-risk-factors> ;
  rdfs:subClassOf obo:SYMP_0000473 .

obo:HP_0031833 a rdfs:Class ;
  rdfs:label "Hypometric upward saccades" ;
  rdfs:comment "Saccadic undershoot of upward saccadic eye movements, i.e., an upward saccadic eye movement that has less than the magnitude that would be required to gain fixation of the object." ;
  rdfs:seeAlso <http://www.efmny.org/epilepsy-101-know-the-facts/types-and-symptoms/> ;
  rdfs:subClassOf obo:HP_0000571 .

obo:HP_0032660 a rdfs:Class ;
  rdfs:label "Convulsive status epilepticus" ;
  rdfs:comment """A type of status epilepticus characterized by a prolonged bilateral tonic-clonic seizure, or repeated bilateral tonic-clonic seizures without recovery between.
comment: 
source: 
seeAlso: Tonic-clonic status epilepticus""" ;
  rdfs:subClassOf obo:HP_0032658 .

obo:BFO_0000015 a rdfs:Class ;
  rdfs:label "process" ;
  rdfs:comment "An occurrent that has temporal proper parts and for some time t, p s-depends_on some material entity at t." ;
  rdfs:subClassOf obo:BFO_0000003 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#focal_cognitive_seizure_with_anomia> a rdfs:Class ;
  rdfs:label "focal cognitive seizure with anomia" ;
  rdfs:subClassOf <https://bio.scai.fraunhofer.de/ontology/epilepsy#focal_cognitive_seizure> .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#primary_visual_cortex_seizure> a rdfs:Class ;
  rdfs:label "primary visual cortex seizure" ;
  rdfs:subClassOf <https://bio.scai.fraunhofer.de/ontology/epilepsy#occipital_lobe_seizure> .

obo:OBI_0000454 a rdfs:Class ;
  rdfs:label "extracellular electrophysiology recording assay" ;
  rdfs:comment "An electrophysiology recording assay where the recording location of the electrode is extracellular" ;
  rdfs:subClassOf obo:OBI_0000070 .

obo:DOID_2916 a rdfs:Class ;
  rdfs:label "hypersensitivity reaction type IV disease" ;
  rdfs:comment "A hypersensitivity reaction disease that is characterized by a cell-mediated response to antigens, where Th1 helper T cells react with antigens on antigen-presenting cells and cause a delayed type immune response." ;
  rdfs:subClassOf obo:DOID_0060056 .

obo:DOID_0050161 a rdfs:Class ;
  rdfs:label "lower respiratory tract disease" ;
  rdfs:comment "A respiratory system disease which involves the lower respiratory tract." ;
  rdfs:subClassOf obo:DOID_1579 .

obo:SYMP_0000834 a rdfs:Class ;
  rdfs:label "hypoesthesia" ;
  rdfs:comment "Hypoesthesia is a general symptom where there is a diminished sensitivity to stimulation." ;
  rdfs:subClassOf obo:SYMP_0000892 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#twisting> a rdfs:Class ;
  rdfs:label "twisting" ;
  rdfs:subClassOf obo:HP_0011175 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#6Hz_phantom_spike_and_wave> a rdfs:Class ;
  rdfs:label "6Hz phantom spike and wave" ;
  rdfs:seeAlso <https://emedicine.medscape.com/article/1140563-overview#a1> , <http://www.case.edu/EpSO.owl#Six-HertzSpikeWaveBurst> ;
  rdfs:subClassOf <https://bio.scai.fraunhofer.de/ontology/epilepsy#epileptiform_benign_variant> .

obo:OMIT_0022847 a rdfs:Class ;
  rdfs:label "Hemispherectomy" ;
  rdfs:subClassOf obo:OMIABIS_0001041 .

obo:UBERON_0000988 a rdfs:Class ;
  rdfs:label "pons" ;
  rdfs:comment "The part of the central nervous system lying between the medulla oblongata and the midbrain, ventral to the cerebellum." ;
  rdfs:subClassOf obo:UBERON_0002616 .

obo:HP_0002781 a rdfs:Class ;
  rdfs:label "Upper airway obstruction" ;
  rdfs:comment "Increased resistance to the passage of air in the upper airway." ;
  rdfs:subClassOf obo:HP_0001279 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#ambulatory_electroencephalography> a rdfs:Class ;
  rdfs:label "ambulatory electroencephalography" ;
  rdfs:seeAlso <https://www.epilepsysociety.org.uk/eeg-electroencephalogram#.XFE6tFwzbIU> ;
  rdfs:subClassOf obo:OBI_0002186 .

obo:NCIT_C40438 a rdfs:Class ;
  rdfs:label "Beck Depression Inventory" ;
  rdfs:comment "A twenty-one question survey completed by a patient, with each answer scored on a scale of 0 to 3, designed to measure presence of depression." ;
  rdfs:subClassOf obo:NCIT_C20993 .

obo:MONDO_0016686 a rdfs:Class ;
  rdfs:label "diffuse astrocytoma" ;
  rdfs:comment "A low-grade (WHO grade II) astrocytic neoplasm. It is characterized by diffuse infiltration of neighboring central nervous system structures. These lesions typically affect young adults and have a tendency for progression to anaplastic astrocytoma and glioblastoma. Based on the IDH genes mutation status, diffuse astrocytomas are classified as IDH-mutant, IDH-wildtype, and not otherwise specified." ;
  rdfs:subClassOf obo:MONDO_0016685 , obo:MONDO_0021639 .

obo:HP_0032671 a rdfs:Class ;
  rdfs:label "Non-convulsive status epilepticus without coma" ;
  rdfs:comment "A type of status epilepticus without prominent motor symptoms in the absence of coma." ;
  rdfs:subClassOf obo:HP_0031475 .

obo:HP_0040081 a rdfs:Class ;
  rdfs:label "Abnormal circulating creatine kinase concentration" ;
  rdfs:comment "Any deviation from the normal circulating creatine kinase concentration." ;
  rdfs:subClassOf obo:HP_0011021 .

obo:SYMP_0000585 a rdfs:Class ;
  rdfs:label "sleep related movement disorder" ;
  rdfs:subClassOf obo:DOID_535 .

obo:HP_0010876 a rdfs:Class ;
  rdfs:label "Abnormal circulating protein level" ;
  rdfs:comment "An abnormal level of a circulating protein in the blood." ;
  rdfs:subClassOf obo:HP_0032180 .

obo:NCIT_C45234 a rdfs:Class ;
  rdfs:label "Wound Infection" ;
  rdfs:comment "Infection of a break in the skin or other tissue." ;
  rdfs:subClassOf obo:IDO_0000586 .

obo:HP_0032252 a rdfs:Class ;
  rdfs:label "Granuloma" ;
  rdfs:comment "A compact, organized collection of mature mononuclear phagocytes, which may be but is not necessarily accompanied by accessory features such as necrosis." ;
  rdfs:seeAlso <http://www.case.edu/EpSO.owl#Granulomas> ;
  rdfs:subClassOf obo:HP_0032251 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#4-aminopyridine-induced_seizure> a rdfs:Class ;
  rdfs:label "4-aminopyridine-induced seizure" ;
  rdfs:subClassOf <https://bio.scai.fraunhofer.de/ontology/epilepsy#toxic_cause_of_seizure> .

obo:OMIT_0007957 a rdfs:Class ;
  rdfs:label "Hunger" ;
  rdfs:seeAlso <https://my.clevelandclinic.org/health/diseases/17778-temporal-lobe-seizures> ;
  rdfs:subClassOf obo:GO_0007610 .

obo:UBERON_0002586 a rdfs:Class ;
  rdfs:label "calcarine sulcus" ;
  rdfs:comment "The calcarine fissure is an anatomical landmark located at the caudal end of the medial surface of the brain. [WP,unvetted]." ;
  rdfs:subClassOf obo:UBERON_0013118 .

obo:HP_0001871 a rdfs:Class ;
  rdfs:label "Abnormality of blood and blood-forming tissues" ;
  rdfs:comment "An abnormality of the hematopoietic system." ;
  rdfs:subClassOf obo:HP_0000118 .

obo:SYMP_0000051 a rdfs:Class ;
  rdfs:label "hydrocephalus" ;
  rdfs:comment "doid/symp duplicate" ;
  rdfs:subClassOf obo:SYMP_0000387 .

obo:NCIT_C107543 a rdfs:Class ;
  rdfs:label "Treatment Satisfaction Questionnaire for Medication" ;
  rdfs:comment "A 9 question subset of the Treatment Satisfaction Questionnaire for Medication that omits the five items of the side effects domain." ;
  rdfs:subClassOf obo:NCIT_C91105 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#focal_cognitive_seizure> a rdfs:Class ;
  rdfs:label "focal cognitive seizure" ;
  rdfs:subClassOf <https://bio.scai.fraunhofer.de/ontology/epilepsy#focal_non-motor_onset_seizure> .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#frontopolar_epilepsy> a rdfs:Class ;
  rdfs:label "frontopolar epilepsy" ;
  rdfs:seeAlso <http://www.case.edu/EpSO.owl#FrontopolarEpilepsy> ;
  rdfs:subClassOf <https://bio.scai.fraunhofer.de/ontology/epilepsy#lateral_frontal_epilepsy> .

obo:SYMP_0019176 a rdfs:Class ;
  rdfs:label "malaise" ;
  rdfs:comment "Malaise is a neurological and physiological symptom characterized as an indefinite feeling of debility or lack of health often indicative of or accompanying the onset of an illness." ;
  rdfs:seeAlso <https://www.epilepsy.com/learn/professionals/co-existing-disorders/metabolic-disorders/electrolyte-abnormalities/hyponatremia> ;
  rdfs:subClassOf obo:SYMP_0000410 .

obo:CLO_0037199 a rdfs:Class ;
  rdfs:label "mouse DBA/2 inbred strain" ;
  rdfs:subClassOf obo:NCBITaxon_10090 .

obo:DOID_18 a rdfs:Class ;
  rdfs:label "urinary system disease" ;
  rdfs:comment "A disease of anatomical entity that is located_in kidney, ureter, bladder and urethra." ;
  rdfs:subClassOf obo:DOID_7 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#rhythmic_benign_variant> a rdfs:Class ;
  rdfs:label "rhythmic benign variant" ;
  rdfs:seeAlso <http://www.case.edu/EpSO.owl#RhythmicBenignVariant> ;
  rdfs:subClassOf <https://bio.scai.fraunhofer.de/ontology/epilepsy#benign_EEG_pattern> .

obo:NCIT_C74742 a rdfs:Class ;
  rdfs:label "Hormone Measurement" ;
  rdfs:comment "The determination of the amount of hormone present in a sample." ;
  rdfs:subClassOf obo:CMO_0000000 .

obo:SYMP_0000600 a rdfs:Class ;
  rdfs:label "apnea" ;
  rdfs:comment "Apnea is a respiratory abnormality characterized by transient cessation of respiration whether normal (as in hibernating animals) or abnormal (as that caused by certain drugs)." ;
  rdfs:subClassOf obo:SYMP_0000598 .

obo:OGMS_0000108 a rdfs:Class ;
  rdfs:label "health care process assay" ;
  rdfs:comment "A health care process with the objective to produce information about the material entity that is the evaluant, by physically examining it or its proxies." ;
  rdfs:subClassOf obo:OGMS_0000096 .

obo:HP_0031815 a rdfs:Class ;
  rdfs:label "Abnormal oral physiology" ;
  rdfs:comment "A functional anomaly of the mouth (which is also known as the oral cavity)." ;
  rdfs:subClassOf obo:HP_0000153 .

obo:SYMP_0000874 a rdfs:Class ;
  rdfs:label "hematoma" ;
  rdfs:comment "Hematoma is a skin and integumentary tissue symptom characterized by a mass of usually clotted blood that forms in a tissue, organ, or body space as a result of a broken blood vessel generally the result of hemorrhage, or more specifically, internal bleeding." ;
  rdfs:subClassOf obo:SYMP_0000488 .

obo:OBI_0002186 a rdfs:Class ;
  rdfs:label "electroencephalography" ;
  rdfs:comment "An extracellular electrophysiology assay where electrodes are mounted outside the brain (either on the surface of the scalp on onto the brain surface itself during surgery) to measure the electrical field over the external surface." ;
  rdfs:subClassOf obo:OBI_0000454 .

obo:DOID_0050847 a rdfs:Class ;
  rdfs:label "sleep apnea" ;
  rdfs:comment "A sleep disorder characterized by repeated cessation and commencing of breathing that repeatedly disrupts sleep." ;
  rdfs:subClassOf obo:NBO_0000419 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#non-epileptic_head_drop> a rdfs:Class ;
  rdfs:label "non-epileptic head drop" ;
  rdfs:subClassOf obo:NCIT_C69023 .

obo:MFOMD_0000211 a rdfs:Class ;
  rdfs:label "thought disorder (TD)" ;
  rdfs:comment "Refers to disorganized thinking as evidenced by disorganized speech." ;
  rdfs:subClassOf obo:MFOMD_0000024 .

obo:DOID_331 a rdfs:Class ;
  rdfs:label "central nervous system disease" ;
  rdfs:comment "A nervous system disease that affects either the spinal cord (myelopathy) or brain (encephalopathy) of the central nervous system." ;
  rdfs:subClassOf obo:DOID_863 .

obo:MONDO_0005070 a rdfs:Class ;
  rdfs:label "neoplasm (disease)" ;
  rdfs:comment "A benign or malignant tissue growth resulting from uncontrolled cell proliferation. Benign neoplastic cells resemble normal cells without exhibiting significant cytologic atypia, while malignant cells exhibit overt signs such as dysplastic features, atypical mitotic figures, necrosis, nuclear pleomorphism, and anaplasia. Representative examples of benign neoplasms include papillomas, cystadenomas, and lipomas; malignant neoplasms include carcinomas, sarcomas, lymphomas, and leukemias." ;
  rdfs:subClassOf obo:MONDO_0023370 .

obo:DOID_9993 a rdfs:Class ;
  rdfs:label "hypoglycemia" ;
  rdfs:comment "A glucose metabolism disease that is characterized by abnormally low levels of blood glucose." ;
  rdfs:seeAlso <https://www.epilepsy.com/learn/professionals/co-existing-disorders/metabolic-disorders/electrolyte-abnormalities/hypoglycemia> ;
  rdfs:subClassOf obo:DOID_26 , obo:DOID_4194 .

obo:DOID_7725 a rdfs:Class ;
  rdfs:label "epilepsy with generalized tonic-clonic seizures" ;
  rdfs:comment "An adolescence-adult electroclinical syndrome starting in adolescence exhibiting generalized tonic-clonic seizures as the only seizure type." ;
  rdfs:subClassOf obo:DOID_1827 , obo:MONDO_0100030 .

obo:HP_0011157 a rdfs:Class ;
  rdfs:label "Focal sensory seizure" ;
  rdfs:comment "A focal sensory seizure involves a sensation being experienced at seizure onset, without objective clinical signs of a seizure evident to the observer." ;
  rdfs:seeAlso <https://www.epilepsydiagnosis.org/seizure/sensory-overview.html> ;
  rdfs:subClassOf <https://bio.scai.fraunhofer.de/ontology/epilepsy#focal_non-motor_onset_seizure> .

obo:HP_0030895 a rdfs:Class ;
  rdfs:label "Abnormal gastrointestinal motility" ;
  rdfs:comment "An anomaly of the muscular contractions that propel food though the gastrointestinal tract." ;
  rdfs:subClassOf obo:HP_0012719 .

obo:RS_0000461 a rdfs:Class ;
  rdfs:label "mutant strain" ;
  rdfs:comment "Rat strains  carrying mutated alleles, spontaneously occurred, chemical-induced,  genome-edited and others, are  included in the mutant strain." ;
  rdfs:subClassOf obo:RS_0000457 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#focal_motor_seizure_with_paresis/paralysis> a rdfs:Class ;
  rdfs:label "focal motor seizure with paresis/paralysis" ;
  rdfs:subClassOf obo:HP_0011153 .

obo:PW_0000138 a rdfs:Class ;
  rdfs:label "vitamin B6 metabolic pathway" ;
  rdfs:comment "Those metabolic reactions involving vitamin B6 - a water-soluble vitamin that exists in several forms. Vitamin B6 is required for many enzymatic reactions as the active pyridoxal 5'-phosphate (PLP) form. A number of organisms can carry out de novo synthesis of vitamin B6; humans derive it from diet." ;
  rdfs:subClassOf obo:PW_0000001 .

obo:BFO_0000009 a rdfs:Class ;
  rdfs:label "two-dimensional spatial region" ;
  rdfs:subClassOf obo:BFO_0000006 .

obo:UBERON_0002751 a rdfs:Class ;
  rdfs:label "inferior temporal gyrus" ;
  rdfs:comment "Component of the temporal lobe, lateral aspect. The rostral boundary is the rostral extent of the inferior temporal sulcus whereas the caudal boundary is designated as the temporo-occipital incisure on the cortical surface. The occipitotemporal sulcus is the medial boundary and the inferior temporal sulcus is the lateral boundary (Christine Fennema-Notestine)." ;
  rdfs:subClassOf obo:UBERON_0000200 .

obo:UBERON_0002915 a rdfs:Class ;
  rdfs:label "postcentral sulcus of parietal lobe" ;
  rdfs:comment "The postcentral sulcus of the parietal lobe lies parallel to, and behind, the central sulcus in the human brain. (A sulcus is one of the prominent grooves on the surface of the brain. ) The postcentral sulcus divides the postcentral gyrus from the remainder of the parietal lobe. [WP,unvetted]." ;
  rdfs:subClassOf obo:UBERON_0035927 .

obo:HP_0011276 a rdfs:Class ;
  rdfs:label "Vascular skin abnormality" ;
  rdfs:subClassOf obo:HP_0002597 , obo:HP_0011354 .

obo:UBERON_0002264 a rdfs:Class ;
  rdfs:label "olfactory bulb" ;
  rdfs:comment "A bulbous anterior projection of the olfactory lobe that is the place of termination of the olfactory nerves and is especially well developed in lower vertebrates (as fishes)[BTO]." ;
  rdfs:subClassOf obo:UBERON_0002616 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#electrically_kindled_cat> a rdfs:Class ;
  rdfs:label "electrically kindled cat" ;
  rdfs:subClassOf obo:NCIT_C19300 .

obo:ERO_0001071 a rdfs:Class ;
  rdfs:label "cerebro-spinal tap" ;
  rdfs:comment "A technique used to collect cerebrospinal fluid (CSF) from an organism, which involves inserting a needle between the third and fourth lumbar vertebrae in the back and extracting a sample of fluid." ;
  rdfs:subClassOf obo:OBI_0000094 .

obo:HP_0012418 a rdfs:Class ;
  rdfs:label "Hypoxemia" ;
  rdfs:comment "An abnormally low level of blood oxygen." ;
  rdfs:subClassOf obo:HP_0500165 .

obo:HP_0012719 a rdfs:Class ;
  rdfs:label "Functional abnormality of the gastrointestinal tract" ;
  rdfs:comment "Abnormal functionality of the gastrointestinal tract." ;
  rdfs:subClassOf obo:HP_0011024 , obo:HP_0025032 .

obo:NBO_0000432 a rdfs:Class ;
  rdfs:label "acoustic startle reflex" ;
  rdfs:comment "\"An action or movement due to the application of a sudden unexpected loud noise.\" [NBO:GVG]" ;
  rdfs:seeAlso <https://www.epilepsy.com/learn/professionals/about-epilepsy-seizures/reflex-seizures-and-related-epileptic-syndromes/startle> ;
  rdfs:subClassOf obo:NBO_0000391 .

obo:BFO_0000028 a rdfs:Class ;
  rdfs:label "three-dimensional spatial region" ;
  rdfs:subClassOf obo:BFO_0000006 .

obo:NCIT_C34721 a rdfs:Class ;
  rdfs:label "Hysteria" ;
  rdfs:comment "A psychological state of emotional lability characterized by irrational behavior. This is a colloquial term that is not commonly used in clinical medicine." ;
  rdfs:subClassOf obo:DOID_1510 .

obo:HP_0003228 a rdfs:Class ;
  rdfs:label "Hypernatremia" ;
  rdfs:comment "An abnormally increased sodium concentration in the blood." ;
  rdfs:seeAlso <https://www.epilepsy.com/learn/professionals/co-existing-disorders/metabolic-disorders/electrolyte-abnormalities-0> ;
  rdfs:subClassOf obo:HP_0010931 .

obo:HP_0011024 a rdfs:Class ;
  rdfs:label "Abnormality of the gastrointestinal tract" ;
  rdfs:comment "An abnormality of the gastrointestinal tract." ;
  rdfs:subClassOf obo:HP_0025031 .

obo:DOID_0060084 a rdfs:Class ;
  rdfs:label "cell type benign neoplasm" ;
  rdfs:comment "A benign neoplasm that is classified by the type of cell or tissue from which it is derived." ;
  rdfs:subClassOf obo:DOID_0060072 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#lambda_wave> a rdfs:Class ;
  rdfs:label "lambda wave" ;
  rdfs:seeAlso <http://www.case.edu/EpSO.owl#LambdaWave> , <https://emedicine.medscape.com/article/1139332-overview#a1> ;
  rdfs:subClassOf <https://bio.scai.fraunhofer.de/ontology/epilepsy#normal_EEG_pattern> .

obo:DOID_3393 a rdfs:Class ;
  rdfs:label "coronary artery disease" ;
  rdfs:comment "An artery disease that is characterized by plaque building up along the inner walls of the arteries of the heart resulting in a narrowing of the arteries and a reduced blood supply to the cardiac muscles." ;
  rdfs:subClassOf obo:DOID_0050828 .

obo:MONDO_0021081 a rdfs:Class ;
  rdfs:label "anti-NMDA receptor encephalitis" ;
  rdfs:comment "An autoimmune acute encephalitis caused by antibodies against the glutamate NMDA receptor. It usually affects females and in the majority of cases it is associated with the presence of a tumor, most commonly an ovarian teratoma. The presence of a tumor in patients with this form of encephalitis implies that the latter is a paraneoplastic syndrome. It is manifested with psychiatric symptoms and epileptic seizures. It is a potentially lethal disorder; however, it is usually reversible with the prompt removal of the tumor." ;
  rdfs:subClassOf obo:MONDO_0100029 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#intracranial_infection> a rdfs:Class ;
  rdfs:label "intracranial infection" ;
  rdfs:subClassOf obo:IDO_0000586 .

obo:HP_0100543 a rdfs:Class ;
  rdfs:label "Cognitive impairment" ;
  rdfs:comment "Abnormality in the process of thought including the ability to process information." ;
  rdfs:subClassOf obo:HP_0011446 .

obo:DOID_0050742 a rdfs:Class ;
  rdfs:label "nicotine dependence" ;
  rdfs:comment "A substance dependence that is characterized by a physical dependence on nicotine." ;
  rdfs:subClassOf obo:DOID_9973 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#stereotactic_radiotherapy> a rdfs:Class ;
  rdfs:label "stereotactic radiotherapy" ;
  rdfs:subClassOf <https://bio.scai.fraunhofer.de/ontology/epilepsy#non-invasive_preoperative_evaluation> .

obo:HP_0010847 a rdfs:Class ;
  rdfs:label "EEG with spike-wave complexes (<2.5 Hz)" ;
  rdfs:comment "The presence of complexes of slow spikes and slow waves (<2.5 Hz) in electroencephalography (EEG)." ;
  rdfs:subClassOf obo:HP_0010850 .

obo:NCIT_C20080 a rdfs:Class ;
  rdfs:label "Angiography" ;
  rdfs:comment "The X-ray examination of the blood vessels or chambers of the heart." ;
  rdfs:seeAlso <http://epilepsyontario.org/wada-test/> ;
  rdfs:subClassOf obo:ERO_0001312 .

obo:UBERON_0016529 a rdfs:Class ;
  rdfs:label "cortex of cerebral lobe" ;
  rdfs:comment "Grey matter neocortex region of a lobe of the cerebral hemisphere." ;
  rdfs:subClassOf obo:UBERON_0002020 , obo:UBERON_0005401 .

obo:SYMP_0000462 a rdfs:Class ;
  rdfs:label "symptom" ;
  rdfs:comment "A symptom is a perceived change in function, sensation, loss, disturbance or appearance reported by a patient indicative of a disease." ;
  rdfs:subClassOf obo:BFO_0000017 .

obo:NBO_0000545 a rdfs:Class ;
  rdfs:label "swallowing" ;
  rdfs:comment "The act of moving food from the mouth cavity to the esophagus through coordinated muscular movements [NBO:AC]" ;
  rdfs:seeAlso <https://www.mayoclinic.org/diseases-conditions/temporal-lobe-seizure/symptoms-causes/syc-20378214> ;
  rdfs:subClassOf obo:NBO_0000079 .

obo:DOID_1891 a rdfs:Class ;
  rdfs:label "optic nerve disease" ;
  rdfs:comment "A cranial nerve disease that is located_in the optic nerve." ;
  rdfs:subClassOf obo:DOID_5656 .

<https://bio.scai.fraunhofer.de/ontology/0000408> a rdfs:Class ;
  rdfs:label "epilepsy imitator TM_BIN" ;
  rdfs:comment "The 'epilepsy imitator TM_BIN' concept enables a compilation of diverse concepts that are related to imitators of Epilepsy via the Axiome 'isImitatorFor some epilepsy'.  Thus enables the adaptation of the ontology for text mining purposes for Epilepsy related information retrieval and information extraction." .

obo:MFOMD_0000188 a rdfs:Class ;
  rdfs:label "dysphoria" ;
  rdfs:comment """Feeling of emotional and mental discomfort as a symptom of discontentment, restlessness, dissatisfaction, malaise, depression, anxiety or indifference.


http://en.wikipedia.org/wiki/Dysphoria """ ;
  rdfs:seeAlso <https://www.frontiersin.org/10.3389/conf.fnhum.2012.210.00006/event_abstract> ;
  rdfs:subClassOf obo:MFOMD_0000024 .

obo:UBERON_0005162 a rdfs:Class ;
  rdfs:label "multi cell part structure" ;
  rdfs:comment "A structure consisting of multiple cell components but which is not itself a cell and does not have (complete) cells as a part." ;
  rdfs:subClassOf obo:UBERON_0000477 .

obo:MP_0004144 a rdfs:Class ;
  rdfs:label "hypotonia" ;
  rdfs:comment "decreased muscle tension resulting in limpness of the muscles in the resting state, not to be confused with weakness" ;
  rdfs:subClassOf obo:HP_0003808 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#post-ictal> a rdfs:Class ;
  rdfs:label "post-ictal" ;
  rdfs:subClassOf obo:PATO_0001912 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#extratemporal_cortical_resection> a rdfs:Class ;
  rdfs:label "extratemporal cortical resection" ;
  rdfs:subClassOf obo:OMIABIS_0001041 .

obo:NCBITaxon_6656 a rdfs:Class ;
  rdfs:label "Arthropoda" ;
  rdfs:subClassOf obo:NCBITaxon_2759 .

obo:MONDO_0015436 a rdfs:Class ;
  rdfs:label "ring chromosome 20" ;
  rdfs:comment "Ring chromosome 20 syndrome is marked by a characteristic seizure phenotype. Depending on the amount of chromosomal loss and associated mosaicism, ring(20) can be associated with macrocephaly, mild to moderate intellectual deficit, or behavioural problems. In rare cases, brain, kidney or heart malformations may be present." ;
  rdfs:subClassOf obo:MONDO_0019040 .

obo:MP_0004994 a rdfs:Class ;
  rdfs:label "abnormal brain wave pattern" ;
  rdfs:comment "any anomaly in the standard pattern of rhythmic and rapid fluctuation of electrical potential between parts of the brain, often visualized on an electroencephalogram (EEG); the pattern is often measured to diagnose neurological conditions such as seizure disorders (epilepsy)" ;
  rdfs:seeAlso <http://www.case.edu/EpSO.owl#AbnormalEEGPattern> ;
  rdfs:subClassOf obo:HP_0030178 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#dysmature> a rdfs:Class ;
  rdfs:label "dysmature" ;
  rdfs:seeAlso <http://www.case.edu/EpSO.owl#Dysmature> ;
  rdfs:subClassOf obo:HP_0025373 .

obo:DOID_0080122 a rdfs:Class ;
  rdfs:label "mitochondrial DNA depletion syndrome 4a" ;
  rdfs:comment "A mitochondrial DNA depletion syndrome that is characterized by a clinical triad of psychomotor retardation, intractable epilepsy, and liver failure in infants and young children, and has_material_basis_in autosomal recessive inheritance of homozygous or compound heterozygous mutation in the nuclear gene encoding mitochondrial DNA polymerase gamma on chromosome 15q26." ;
  rdfs:subClassOf obo:MONDO_0044970 .

obo:NCIT_C112286 a rdfs:Class ;
  rdfs:label "Ghrelin Measurement" ;
  rdfs:comment "The determination of the amount of ghrelin present in a sample." ;
  rdfs:subClassOf obo:NCIT_C74742 .

obo:HP_0011805 a rdfs:Class ;
  rdfs:label "Abnormal skeletal muscle morphology" ;
  rdfs:comment "A structural abnormality of a skeletal muscle." ;
  rdfs:subClassOf obo:HP_0003011 .

obo:CMO_0000000 a rdfs:Class ;
  rdfs:label "clinical measurement" ;
  rdfs:seeAlso <http://www.case.edu/EpSO.owl#ClinicalEvaluation> ;
  rdfs:subClassOf obo:IAO_0000109 .

obo:NCIT_C16390 a rdfs:Class ;
  rdfs:label "Etiology" ;
  rdfs:comment "The cause of a disease or abnormal condition." ;
  rdfs:subClassOf <https://bio.scai.fraunhofer.de/ontology/epilepsy#International_League_Against_Epilepsy_classification> .

obo:DOID_14069 a rdfs:Class ;
  rdfs:label "cerebral malaria" ;
  rdfs:comment "A malaria that involves neurologic damage resulting from blockage of the blood vessels, caused due to the infection of the red blood cells by Plasmodium species." ;
  rdfs:subClassOf <https://bio.scai.fraunhofer.de/ontology/epilepsy#infectious_etiology> .

obo:MONDO_0011146 a rdfs:Class ;
  rdfs:label "tetrasomy 12p" ;
  rdfs:comment "Pallister-Killian syndrome (PKS) is a rare multiple congenital anomaly/intellectual deficit syndrome caused by mosaic tissue-limited tetrasomy for chromosome 12p." ;
  rdfs:subClassOf obo:MONDO_0019040 .

obo:MONDO_0015584 a rdfs:Class ;
  rdfs:label "febrile infection-related epilepsy syndrome" ;
  rdfs:comment "Febrile infection-related epilepsy syndrome (FIRES) describes an explosive-onset, potentially fatal acute epileptic encephalopathy that develops in previously healthy children and adolescents following the onset of a non-specific febrile illness." ;
  rdfs:subClassOf <https://bio.scai.fraunhofer.de/ontology/epilepsy#unknown_etiology> .

obo:UBERON_0016634 a rdfs:Class ;
  rdfs:label "premotor cortex" ;
  rdfs:comment "The premotor cortex is an area of motor cortex lying within the frontal lobe of the brain. It extends 3 mm anterior to the primary motor cortex, near the Sylvian fissure, before narrowing to approximately 1 mm near the medial longitudinal fissure, which serves as the posterior border for the prefrontal cortex. The premotor cortex is largely equivalent to Brodmann area 6. Activity within this region is critical to the sensory guidance of movement and control of proximal and trunk muscles of the body." ;
  rdfs:subClassOf obo:UBERON_0002616 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#temporo_occipital_epilepsy> a rdfs:Class ;
  rdfs:label "temporo occipital epilepsy" ;
  rdfs:seeAlso <http://www.case.edu/EpSO.owl#TemporoOccipitalEpilepsy> ;
  rdfs:subClassOf obo:DOID_1826 .

obo:HP_0000152 a rdfs:Class ;
  rdfs:label "Abnormality of head or neck" ;
  rdfs:comment "An abnormality of head and neck." ;
  rdfs:subClassOf obo:HP_0000118 .

obo:MONDO_0018200 a rdfs:Class ;
  rdfs:label "acute encephalopathy with inflammation-mediated status epilepticus" ;
  rdfs:subClassOf obo:DOID_1826 , obo:MONDO_0015657 .

obo:DOID_9252 a rdfs:Class ;
  rdfs:label "amino acid metabolic disorder" ;
  rdfs:comment "An inherited metabolic disorder that is characterized by impaired synthesis and degradation of amino acids." ;
  rdfs:subClassOf obo:DOID_655 .

obo:SYMP_0000515 a rdfs:Class ;
  rdfs:label "hiccough" ;
  rdfs:comment "Hiccough is a respiratory system and chest symptom characterized by a spasmodic inhalation with closure of the glottis accompanied by a peculiar sound." ;
  rdfs:subClassOf obo:SYMP_0000514 .

obo:GO_0022601 a rdfs:Class ;
  rdfs:label "menstrual cycle phase" ;
  rdfs:comment "The progression of physiological phases, occurring in the endometrium during the menstrual cycle that recur at regular intervals during the reproductive years. The menstrual cycle is an ovulation cycle where the endometrium is shed if pregnancy does not occur." ;
  rdfs:subClassOf <https://bio.scai.fraunhofer.de/ontology/epilepsy#trigger_factor_for_seizure> .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#6_Hertz_psychomotor> a rdfs:Class ;
  rdfs:label "6 Hertz psychomotor" ;
  rdfs:subClassOf obo:OMIT_0008800 .

obo:HP_0012005 a rdfs:Class ;
  rdfs:label "Deja vu" ;
  rdfs:comment "A subjective feeling that an experience which is occurring for the first time has been experienced before." ;
  rdfs:subClassOf obo:HP_0012004 .

obo:NCIT_C103526 a rdfs:Class ;
  rdfs:label "Patient Health Questionnaire - 9 Item" ;
  rdfs:comment "A 9-item scale using each of the 9 DSM-IV criteria with self-reported frequency of \"0\" (not at all) to \"3\" (nearly every day). One of the most widely used instruments to assess depression, PHQ-9 scores of 5, 10, 15, and 20 represent mild, moderate, moderately severe, and severe depression, respectively." ;
  rdfs:subClassOf obo:NCIT_C91105 .

obo:DOID_2234 a rdfs:Class ;
  rdfs:label "focal epilepsy" ;
  rdfs:comment "An epilepsy syndrome that is characterised by seizures that are preceded by an isolated disturbance of a cerebral function and arise from an epileptic focus, a small portion of the brain that serves as the irritant driving the epileptic response." ;
  rdfs:seeAlso <http://www.case.edu/EpSO.owl#FocalEpilepsy> ;
  rdfs:subClassOf <https://bio.scai.fraunhofer.de/ontology/epilepsy#epilepsy_classification> .

<https://bio.scai.fraunhofer.de/ontology/epilepsy/epilepsy_classification_TM_BIN> a rdfs:Class ;
  rdfs:label "epilepsy classification TM_BIN" ;
  rdfs:comment "The 'epilepsy classification TM_BIN' concept enables a compilation of diverse concepts that are related to classificactions in Epilepsy via the Axiome 'isClassificationFor some epilepsy'.  Thus enables the adaptation of the ontology for text mining purposes for Epilepsy related information retrieval and information extraction." .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#focal_autonomic_seizure_with_lacrimation> a rdfs:Class ;
  rdfs:label "focal autonomic seizure with lacrimation" ;
  rdfs:seeAlso <https://www.epilepsydiagnosis.org/seizure/autonomic-overview.html> , <https://emedicine.medscape.com/article/1186872-overview> ;
  rdfs:subClassOf obo:HP_0011154 .

obo:HP_0002493 a rdfs:Class ;
  rdfs:label "Upper motor neuron dysfunction" ;
  rdfs:comment "A functional anomaly of the upper motor neuron. The upper motor neurons are neurons of the primary motor cortex which project to the brainstem and spinal chord via the corticonuclear, corticobulbar and corticospinal (pyramidal) tracts. They are involved in control of voluntary movements. Dysfunction leads to weakness, impairment of fine motor movements, spasticity, hyperreflexia and abnormal pyramidal signs." ;
  rdfs:subClassOf obo:HP_0011442 .

obo:NCIT_C64862 a rdfs:Class ;
  rdfs:label "Diffusion Tensor Imaging" ;
  rdfs:comment "A type of diffusion-weighted magnetic resonance imaging (DW-MRI) that maps the diffusion of water in three dimensions, the principal purpose of which is to image the white matter of the brain, specifically measuring the anisotropy, location, and orientation of the neural tracts, which can demonstrate microstructural changes or differences with neuropathology and treatment." ;
  rdfs:subClassOf obo:ERO_0001235 .

obo:BFO_0000142 a rdfs:Class ;
  rdfs:label "one-dimensional continuant fiat boundary" ;
  rdfs:subClassOf obo:BFO_0000140 .

obo:NCIT_C34865 a rdfs:Class ;
  rdfs:label "Optical Illusion" ;
  rdfs:comment "The visual perception of an image that differs from the reality of the image." ;
  rdfs:seeAlso <https://eyewiki.aao.org/Ophthalmologic_Manifestations_of_Epilepsy> ;
  rdfs:subClassOf obo:MF_0000019 .

obo:HP_0000014 a rdfs:Class ;
  rdfs:label "Abnormality of the bladder" ;
  rdfs:comment "An abnormality of the urinary bladder." ;
  rdfs:subClassOf obo:HP_0010936 .

obo:NBO_0000707 a rdfs:Class ;
  rdfs:label "gestural automatism" ;
  rdfs:comment "\"An automatism characterised by involuntary movement of the limbs or body such as  fumbling, picking and rubbing.\" [NBO:GVG]" ;
  rdfs:subClassOf obo:NBO_0000705 .

obo:HP_0100000 a rdfs:Class ;
  rdfs:label "Early onset of sexual maturation" ;
  rdfs:comment "An early onset of puberty, in this case early does not refer to precocious." ;
  rdfs:subClassOf obo:HP_0008373 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#special_pattern> a rdfs:Class ;
  rdfs:label "special pattern" ;
  rdfs:seeAlso <http://www.case.edu/EpSO.owl#SpecialPattern> ;
  rdfs:subClassOf obo:HP_0002353 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#1.5_Tesla_magnetic_resonance_imaging> a rdfs:Class ;
  rdfs:label "1.5 Tesla magnetic resonance imaging" ;
  rdfs:seeAlso <https://jamanetwork.com/journals/jamaneurology/article-abstract/585216> ;
  rdfs:subClassOf obo:ERO_0001235 .

obo:UBERON_0000956 a rdfs:Class ;
  rdfs:label "cerebral cortex" ;
  rdfs:comment "The thin layer of gray matter on the surface of the cerebral hemisphere that develops from the telencephalon. It consists of the neocortex (6 layered cortex or isocortex), the hippocampal formation and the olfactory cortex." ;
  rdfs:seeAlso <http://www.case.edu/EpSO.owl#CerebralCortexRegion> ;
  rdfs:subClassOf obo:UBERON_0011215 , obo:UBERON_0016548 .

obo:NCIT_C120342 a rdfs:Class ;
  rdfs:label "Logical Memory I Subtest (WMS-IV)" ;
  rdfs:comment "A subtest of the Wechsler Memory Scale, 4th Edition that assesses narrative memory under a free recall condition. A short story is presented orally. Immediately after presentation of the story the subject is asked to recall the story from memory." ;
  rdfs:subClassOf obo:NCIT_C20993 .

obo:DOID_3181 a rdfs:Class ;
  rdfs:label "oligodendroglioma" ;
  rdfs:seeAlso <http://www.case.edu/EpSO.owl#Oligodendroglioma> ;
  rdfs:subClassOf obo:MONDO_0015917 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#allylglycine_model> a rdfs:Class ;
  rdfs:label "allylglycine model" ;
  rdfs:subClassOf <https://bio.scai.fraunhofer.de/ontology/epilepsy#convulsant_drug_model> .

obo:UBERON_0006102 a rdfs:Class ;
  rdfs:label "Brodmann (1909) area 35" ;
  rdfs:comment "Brodmann area 35, together with Brodmann area 36, is most frequently referred to as perirhinal cortex." ;
  rdfs:subClassOf obo:UBERON_0013529 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#strychnine_model> a rdfs:Class ;
  rdfs:label "strychnine model" ;
  rdfs:subClassOf <https://bio.scai.fraunhofer.de/ontology/epilepsy#convulsant_drug_model> .

obo:HP_0000951 a rdfs:Class ;
  rdfs:label "Abnormality of the skin" ;
  rdfs:comment "An abnormality of the skin." ;
  rdfs:subClassOf obo:HP_0001574 .

obo:DOID_4852 a rdfs:Class ;
  rdfs:label "pleomorphic xanthoastrocytoma" ;
  rdfs:seeAlso <http://www.case.edu/EpSO.owl#PleomorhicXanthoastrocytoma> ;
  rdfs:subClassOf obo:DOID_3069 .

obo:UBERON_0013559 a rdfs:Class ;
  rdfs:label "Brodmann (1909) area 28" ;
  rdfs:comment "." ;
  rdfs:subClassOf obo:UBERON_0013529 .

obo:DOID_1825 a rdfs:Class ;
  rdfs:label "childhood absence epilepsy" ;
  rdfs:comment "A childhood electroclinical syndrome that is characterized by brief and frequent absence seizures in children with age of onset between four and ten years." ;
  rdfs:seeAlso <http://www.case.edu/EpSO.owl#ChildhoodAbsenceEpilepsy> ;
  rdfs:subClassOf obo:DOID_1827 , obo:MONDO_0020072 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#lateral_frontal_epilepsy> a rdfs:Class ;
  rdfs:label "lateral frontal epilepsy" ;
  rdfs:seeAlso <http://www.case.edu/EpSO.owl#LateralFrontalEpilepsy> ;
  rdfs:subClassOf obo:DOID_3331 .

obo:DOID_10763 a rdfs:Class ;
  rdfs:label "hypertension" ;
  rdfs:comment "An artery disease characterized by chronic elevated blood pressure in the arteries." ;
  rdfs:subClassOf obo:DOID_0050828 .

obo:UBERON_0013528 a rdfs:Class ;
  rdfs:label "Brodmann (1909) area 11" ;
  rdfs:comment "Brodmann area 11 is one of Brodmann's cytologically defined regions of the brain. It is involved in planning, reasoning, and decision making." ;
  rdfs:subClassOf obo:UBERON_0013529 .

obo:UBERON_0016530 a rdfs:Class ;
  rdfs:label "parietal cortex" ;
  rdfs:comment "Gray matter of the parietal region of the neocortex, located in the parietal lobe of gyrencephalic animals. It is continuous anteriorly with the frontal cortex, posteriorly with the occipital cortex and medially with the insular cortex and with the temporal cortex on the posterior/inferior border." ;
  rdfs:subClassOf obo:UBERON_0016529 .

obo:MONDO_0015648 a rdfs:Class ;
  rdfs:label "startle epilepsy" ;
  rdfs:comment "Startle epilepsy is a rare neurologic disease characterized by frequent and spontaneous epileptic seizures (frequently with symmetrical or asymmetrical tonic features) triggered by a normal startle in response to a sudden and unexpected somatosensory (most frequently auditory) stimulus. Falls are common and can be traumatic. In most cases, the disease is associated with spastic hemi-, di-, or tetraplegia and intellectual disability." ;
  rdfs:subClassOf obo:DOID_2548 .

obo:NBO_0000701 a rdfs:Class ;
  rdfs:label "typical absence seizure" ;
  rdfs:comment "\"An absence seizure induced by hyperventilation.\" [NBO:GVG]" ;
  rdfs:subClassOf <https://bio.scai.fraunhofer.de/ontology/epilepsy#generalized_non-motor_onset_seizure> .

obo:UBERON_0008933 a rdfs:Class ;
  rdfs:label "primary somatosensory cortex" ;
  rdfs:comment "(Chapin & Lin, 1984, rat): the region considered as the SI cortex is not a cytoarchitecturally homogeneous structure but consists instead of a patchwork array of areas containing dense aggregations of layer IV granule cells, surrounded by granule-cell-sparse regions. As was shown by Welker (b71,b76), and in our own mapping studies (see Fig. 3), this discontinuous pattern of granular, or koniocortical, zones contains within itself a map of the ratbs cutaneous periphery. There are clear subtypes within this cytoarchitectural subregion, notably including the bgranular aggregateb type of cytoarchitecture characteristic of the paw, limb, and mystacial vibrissae areas, and the bbarrel-fieldb type (originally described by Woolsey and Van der Loos, b70) seen in the nose and perioral regions. In the mouse, but not the rat, such barrels also cover the whole whisker representation (Welker and Woolsey, b74)." ;
  rdfs:subClassOf obo:UBERON_0008930 .

<https://bio.scai.fraunhofer.de/ontology/0000515> a rdfs:Class ;
  rdfs:label "automotor seizure" ;
  rdfs:subClassOf obo:HP_0020219 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#primary_sensory_area_(post-central_gyrus)_seizure> a rdfs:Class ;
  rdfs:label "primary sensory area (post-central gyrus) seizure" ;
  rdfs:subClassOf <https://bio.scai.fraunhofer.de/ontology/epilepsy#parietal_lobe_seizure> .

obo:NCIT_C81292 a rdfs:Class ;
  rdfs:label "Social History" ;
  rdfs:comment "Past events that occurred between individuals and/or their communities." ;
  rdfs:subClassOf obo:OGMS_0000015 .

obo:NBO_0001845 a rdfs:Class ;
  rdfs:label "consumption behavior" ;
  rdfs:comment "\"Behavior related to the intake of substances.\" [NBOC:GVG]" ;
  rdfs:subClassOf obo:NBO_0000313 .

obo:NBO_0000231 a rdfs:Class ;
  rdfs:label "excitement behavior" ;
  rdfs:subClassOf obo:NBO_0000003 .

obo:ERO_0002178 a rdfs:Class ;
  rdfs:label "functional magnetic resonance imaging" ;
  rdfs:comment "A magnetic resonance imaging technique that measures brain activity by detecting associated changes in blood flow. The procedure is similar to MRI but uses the change in magnetization between oxygen-rich and oxygen-poor blood as its basic measure. " ;
  rdfs:subClassOf obo:ERO_0001235 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#seizure_arising_inferior_to_the_calcarine_fissure> a rdfs:Class ;
  rdfs:label "seizure arising inferior to the calcarine fissure" ;
  rdfs:subClassOf <https://bio.scai.fraunhofer.de/ontology/epilepsy#occipital_lobe_seizure> .

obo:UBERON_0019294 a rdfs:Class ;
  rdfs:label "commissure of telencephalon" ;
  rdfs:subClassOf obo:UBERON_0005970 .

obo:NCIT_C50429 a rdfs:Class ;
  rdfs:label "Missed Dose" ;
  rdfs:comment "A dose of medicine that was not taken at the prescribed dosing interval." ;
  rdfs:seeAlso <https://www.epilepsy.com/learn/triggers-seizures/missed-medicines> ;
  rdfs:subClassOf <https://bio.scai.fraunhofer.de/ontology/epilepsy#trigger_factor_for_seizure> .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#loss_of_awareness> a rdfs:Class ;
  rdfs:label "loss of awareness" ;
  rdfs:seeAlso <https://www.epilepsy.com/learn/types-seizures/focal-onset-impaired-awareness-seizures-aka-complex-partial-seizures> ;
  rdfs:subClassOf obo:SYMP_0019182 .

obo:OBI_0000011 a rdfs:Class ;
  rdfs:label "planned process" ;
  rdfs:comment "A processual entity that realizes a plan which is the concretization of a plan specification." ;
  rdfs:subClassOf obo:BFO_0000015 .

obo:UBERON_0000451 a rdfs:Class ;
  rdfs:label "prefrontal cortex" ;
  rdfs:comment "The anterior part of the frontal lobes of the brain, lying in front of the motor and premotor areas.nnThis brain region has been implicated in planning complex cognitive behaviors, personality expression, decision making and moderating correct social behavior. The basic activity of this brain region is considered to be orchestration of thoughts and actions in accordance with internal goals.nnThe most typical psychological term for functions carried out by the pre-frontal cortex area is executive function. Executive function relates to abilities to differentiate among conflicting thoughts, determine good and bad, better and best, same and different, future consequences of current activities, working toward a defined goal, prediction of outcomes, expectation based on actions, and social 'control' (the ability to suppress urges that, if not suppressed, could lead to socially-unacceptable outcomes).nnMany authors have indicated an integral link between a person's personality and the functions of the prefrontal cortex. - definition adapted from Wikipedia" ;
  rdfs:subClassOf obo:UBERON_0002616 .

obo:OMIT_0028139 a rdfs:Class ;
  rdfs:label "Prodromal Symptoms" ;
  rdfs:subClassOf obo:SYMP_0000462 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#focal_cognitive_seizure_with_dysgraphia/agraphia> a rdfs:Class ;
  rdfs:label "focal cognitive seizure with dysgraphia/agraphia" ;
  rdfs:subClassOf <https://bio.scai.fraunhofer.de/ontology/epilepsy#focal_cognitive_seizure> .

obo:HP_0025236 a rdfs:Class ;
  rdfs:label "Somnambulism" ;
  rdfs:comment "Ambulation or other complex motor behaviors after getting out of bed in a sleep-like state. During sleepwalking episodes, the sonambulating individual appears confused or dazed, the eyes are usually open, and he or she might mumble or give inappropriate answers to questions, or occasionally appear agitated." ;
  rdfs:seeAlso <http://www.case.edu/EpSO.owl#SleepWalking> ;
  rdfs:subClassOf obo:NBO_0000499 .

obo:SYMP_0000486 a rdfs:Class ;
  rdfs:label "urinary system symptom" ;
  rdfs:subClassOf obo:SYMP_0000462 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#3-nitropropionic_acid-induced_seizure> a rdfs:Class ;
  rdfs:label "3-nitropropionic acid-induced seizure" ;
  rdfs:subClassOf <https://bio.scai.fraunhofer.de/ontology/epilepsy#toxic_cause_of_seizure> .

obo:BFO_0000008 a rdfs:Class ;
  rdfs:label "temporal region" ;
  rdfs:subClassOf obo:BFO_0000003 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#neurological_syncope> a rdfs:Class ;
  rdfs:label "neurological syncope" ;
  rdfs:subClassOf obo:HP_0001279 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#pseudostatus_epilepticus> a rdfs:Class ;
  rdfs:label "pseudostatus epilepticus" ;
  rdfs:subClassOf obo:NBO_0000687 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#micro-scale_model> a rdfs:Class ;
  rdfs:label "micro-scale model" ;
  rdfs:subClassOf <https://bio.scai.fraunhofer.de/ontology/epilepsy#deterministic_model> .

obo:DOID_10024 a rdfs:Class ;
  rdfs:label "migraine with aura" ;
  rdfs:comment "A migraine characterized by migraine headache which is preceded or accompanied by a transient focal neurological phenomenon." ;
  rdfs:subClassOf <https://bio.scai.fraunhofer.de/ontology/epilepsy#migraine_associated_disorder> .

obo:DOID_10914 a rdfs:Class ;
  rdfs:label "amnestic disorder" ;
  rdfs:comment "A cognitive disorder where the memory is disturbed or lost and involves the loss of memories previously established, loss of the ability to create new memories, or loss of the ability to learn new information." ;
  rdfs:subClassOf obo:DOID_1561 .

obo:OGMS_0000114 a rdfs:Class ;
  rdfs:label "immunotherapy procedure" ;
  rdfs:comment "A therapeutic procedure that uses immune system derived entities." ;
  rdfs:seeAlso <https://www.medscape.com/answers/1184846-153550/what-is-the-role-of-immunotherapy-in-the-treatment-of-epileptic-seizures> ;
  rdfs:subClassOf obo:OGMS_0000112 .

obo:HP_0032040 a rdfs:Class ;
  rdfs:label "Abnormal ocular adnexa physiology" ;
  rdfs:comment "A functional anomaly of the adjacent structures (i.e., adnexa) of the eye, defined as the lacrimal apparatus, the extraocular muscles and the eyelids, eyelashes, eyebrows and the conjunctiva." ;
  rdfs:subClassOf obo:HP_0032039 .

obo:HP_0012638 a rdfs:Class ;
  rdfs:label "Abnormality of nervous system physiology" ;
  rdfs:comment "A functional anomaly of the nervous system." ;
  rdfs:subClassOf obo:HP_0000707 .

obo:BFO_0000002 a rdfs:Class ;
  rdfs:label "continuant" ;
  rdfs:comment "An entity that exists in full at any time in which it exists at all, persists through time while maintaining its identity and has no temporal parts." ;
  rdfs:subClassOf obo:BFO_0000001 .

obo:DOID_0060469 a rdfs:Class ;
  rdfs:label "Miller-Dieker lissencephaly syndrome" ;
  rdfs:comment "A syndrome characterized by classical lissencephaly and distinct facial features and has_material_basis_in submicroscopic deletions of 17p13.3, including the LIS1 gene." ;
  rdfs:subClassOf obo:MONDO_0019040 .

obo:HP_0011205 a rdfs:Class ;
  rdfs:label "EEG with intermittent slow activity" ;
  rdfs:comment "Non-continuous diffuse slowing of electroencephalographic patterns." ;
  rdfs:seeAlso <http://www.case.edu/EpSO.owl#IntermittentSlowActivity> ;
  rdfs:subClassOf obo:HP_0010845 .

obo:MFOMD_0000162 a rdfs:Class ;
  rdfs:label "akinesia" ;
  rdfs:comment """Absence, poverty, or loss of control of voluntary muscle movements.


http://medical-dictionary.thefreedictionary.com/akinesia""" ;
  rdfs:subClassOf obo:MFOMD_0000024 .

obo:HP_0011804 a rdfs:Class ;
  rdfs:label "Abnormal muscle physiology" ;
  rdfs:comment "A functional abnormality of a skeletal muscle." ;
  rdfs:subClassOf obo:HP_0003011 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#amgdalar_epilepsy> a rdfs:Class ;
  rdfs:label "amgdalar epilepsy" ;
  rdfs:seeAlso <http://www.case.edu/EpSO.owl#AmgdalarEpilepsy> ;
  rdfs:subClassOf obo:DOID_3328 .

obo:MP_0003967 a rdfs:Class ;
  rdfs:label "abnormal follicle stimulating hormone level" ;
  rdfs:comment "anomalous concentration of the hormone that, in females, stimulates the graafian follicles of the ovary and assists in follicular maturation and the secretion of estradiol; in the male it stimulates the epithelium of the seminiferous tubules and is partly responsible for spermatogenesis" ;
  rdfs:subClassOf obo:MP_0003965 .

obo:HP_0001041 a rdfs:Class ;
  rdfs:label "Facial erythema" ;
  rdfs:comment "Redness of the skin of the face, caused by hyperemia of the capillaries in the lower layers of the skin." ;
  rdfs:subClassOf obo:HP_0010783 .

obo:DOID_9335 a rdfs:Class ;
  rdfs:label "scotoma" ;
  rdfs:subClassOf obo:DOID_5614 .

obo:DOID_593 a rdfs:Class ;
  rdfs:label "agoraphobia" ;
  rdfs:comment "A phobic disorder involving the specific anxiety about being in a place or situation where escape is difficult or embarrassing or where help may be unavailable." ;
  rdfs:subClassOf obo:DOID_591 .

obo:HP_0031466 a rdfs:Class ;
  rdfs:label "Impairment in personality functioning" ;
  rdfs:comment "A maladaptive personality trait characterized by moderate or greater impairment in personality (self /interpersonal) functioning." ;
  rdfs:subClassOf obo:HP_0000708 .

obo:UBERON_0006480 a rdfs:Class ;
  rdfs:label "Brodmann (1909) area 39" ;
  rdfs:comment "." ;
  rdfs:subClassOf obo:UBERON_0013529 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#focal_automatism_seizure> a rdfs:Class ;
  rdfs:label "focal automatism seizure" ;
  rdfs:subClassOf obo:HP_0011153 .

obo:DOID_114 a rdfs:Class ;
  rdfs:label "heart disease" ;
  rdfs:comment "A cardiovascular system disease that involves the heart." ;
  rdfs:seeAlso <https://www.epilepsy.com/learn/professionals/co-existing-disorders/cardiac-disorders> ;
  rdfs:subClassOf obo:DOID_1287 .

obo:HP_0004921 a rdfs:Class ;
  rdfs:label "Abnormal magnesium concentration" ;
  rdfs:comment "An abnormality of magnesium ion homeostasis." ;
  rdfs:subClassOf obo:HP_0010927 .

obo:SYMP_0000369 a rdfs:Class ;
  rdfs:label "ptosis" ;
  rdfs:comment "Ptosis is a general symptom characterized by a sagging or prolapse of an organ or part." ;
  rdfs:subClassOf obo:SYMP_0000567 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#combined_generalized_and_focal_epilepsy> a rdfs:Class ;
  rdfs:label "combined generalized and focal epilepsy" ;
  rdfs:subClassOf <https://bio.scai.fraunhofer.de/ontology/epilepsy#epilepsy_classification> .

obo:HP_0002615 a rdfs:Class ;
  rdfs:label "Hypotension" ;
  rdfs:comment "Low Blood Pressure, vascular hypotension." ;
  rdfs:subClassOf obo:HP_0030972 .

obo:CMO_0000114 a rdfs:Class ;
  rdfs:label "ventilation measurement" ;
  rdfs:subClassOf obo:CMO_0000094 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#quality_of_life_in_epilepsy_inventory_-_31> a rdfs:Class ;
  rdfs:label "quality of life in epilepsy inventory - 31" ;
  rdfs:seeAlso <https://www.epilepsy.com/sites/core/files/atoms/files/QOLIE-31%20for%20web-USA.pdf> ;
  rdfs:subClassOf obo:NCIT_C20993 .

obo:DOID_0060031 a rdfs:Class ;
  rdfs:label "autoimmune disease of gastrointestinal tract" ;
  rdfs:comment "An autoimmune hypersensitivity disease that is the abnormal functioning of the immune system that causes your immune system to produce antibodies or T cells against cells and/or tissues in the gastrointestinal tract." ;
  rdfs:subClassOf obo:DOID_417 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#screeching> a rdfs:Class ;
  rdfs:label "screeching" ;
  rdfs:subClassOf obo:GO_0007610 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#occipital_lobe_seizure> a rdfs:Class ;
  rdfs:label "occipital lobe seizure" ;
  rdfs:seeAlso <https://www.epilepsy.com/learn/professionals/about-epilepsy-seizures/symptomatic-and-probably-symptomatic-focal-epilepsies-1> ;
  rdfs:subClassOf <https://bio.scai.fraunhofer.de/ontology/epilepsy#seizure_based_on_lobar_localization> .

obo:DOID_0111169 a rdfs:Class ;
  rdfs:label "subcortical band heterotopia" ;
  rdfs:comment "A congenital nervous system abnormality characterized by migration of neurons to ectopic locations in the brain where the neurons form areas that appear as band-like clusters of white tissue underneath the gray tissue of the cerebral cortex." ;
  rdfs:subClassOf obo:NCIT_C84834 .

obo:DOID_0060115 a rdfs:Class ;
  rdfs:label "nervous system benign neoplasm" ;
  rdfs:comment "An organ system benign neoplasm that is located_in the central nervous system or located_in the peripheral nervous system." ;
  rdfs:subClassOf obo:DOID_0060085 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#vasomotor_seizure> a rdfs:Class ;
  rdfs:label "vasomotor seizure" ;
  rdfs:seeAlso <http://www.case.edu/EpSO.owl#VasomotorSeizure> ;
  rdfs:subClassOf obo:SYMP_0000124 .

obo:DOID_11465 a rdfs:Class ;
  rdfs:label "autonomic nervous system disease" ;
  rdfs:subClassOf obo:DOID_574 .

obo:UBERON_0004717 a rdfs:Class ;
  rdfs:label "Brodmann (1909) area 29" ;
  rdfs:comment "Brodmann area 29, also known as granular retrolimbic area 29 or granular retrosplenial cortex, is a cytoarchitecturally defined portion of the retrosplenial region of the cerebral cortex. In the human it is a narrow band located in the isthmus of cingulate gyrus. Cytoarchitecturally it is bounded internally by the ectosplenial area 26 and externally by the agranular retrolimbic area 30 (Brodmann-1909)." ;
  rdfs:subClassOf obo:UBERON_0013529 .

obo:MONDO_0023370 a rdfs:Class ;
  rdfs:label "neoplastic disease or syndrome" ;
  rdfs:comment "Either an isolated neoplasm or a syndrome with neoplasm as a major feature." ;
  rdfs:subClassOf obo:DOID_14566 .

obo:PATO_0000085 a rdfs:Class ;
  rdfs:label "sensitivity toward" ;
  rdfs:comment "A quality inhering in a bearer by virtue of the bearer's disposition to detect or perceive external stimulation." ;
  rdfs:subClassOf obo:PATO_0001995 .

obo:CMO_0000496 a rdfs:Class ;
  rdfs:label "blood potassium level" ;
  rdfs:seeAlso <https://www.webmd.com/epilepsy/guide/epilepsy-blood-test> ;
  rdfs:subClassOf obo:CMO_0000063 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#neurological_disorders_depression_inventory_for_epilepsy> a rdfs:Class ;
  rdfs:label "neurological disorders depression inventory for epilepsy" ;
  rdfs:subClassOf obo:NCIT_C20993 .

obo:UBERON_0000061 a rdfs:Class ;
  rdfs:label "anatomical structure" ;
  rdfs:comment "Material anatomical entity that is a single connected structure with inherent 3D shape generated by coordinated expression of the organism's own genome." ;
  rdfs:subClassOf obo:UBERON_0000465 .

obo:DOID_409 a rdfs:Class ;
  rdfs:label "liver disease" ;
  rdfs:seeAlso <https://www.epilepsy.com/learn/professionals/co-existing-disorders/gastrointestinal-liver-disease> ;
  rdfs:subClassOf obo:DOID_28 , obo:DOID_3118 .

obo:HP_0012377 a rdfs:Class ;
  rdfs:label "Hemianopia" ;
  rdfs:comment "Partial or complete loss of vision in one half of the visual field of one or both eyes." ;
  rdfs:subClassOf obo:HP_0001123 .

obo:MMO_0000433 a rdfs:Class ;
  rdfs:label "urine electrolyte analysis" ;
  rdfs:comment "A method which assesses the amount, proportions or properties of one or more electrolytes, any of various ions required by cells to regulate the electric charge and flow of water molecules across the cell membrane, in urine, the fluid waste product excreted by the kidneys." ;
  rdfs:subClassOf obo:MMO_0000147 .

obo:MONDO_0019385 a rdfs:Class ;
  rdfs:label "steroid-responsive encephalopathy associated with autoimmune thyroiditis" ;
  rdfs:comment "Editor note: TODO DP for chebi roles" ;
  rdfs:subClassOf obo:MONDO_0100029 .

obo:HP_0000505 a rdfs:Class ;
  rdfs:label "Visual impairment" ;
  rdfs:comment "Visual impairment (or vision impairment) is vision loss (of a person) to such a degree as to qualify as an additional support need through a significant limitation of visual capability resulting from either disease, trauma, or congenital or degenerative conditions that cannot be corrected by conventional means, such as refractive correction, medication, or surgery." ;
  rdfs:subClassOf obo:HP_0000504 .

obo:NCBITaxon_6157 a rdfs:Class ;
  rdfs:label "Platyhelminthes" ;
  rdfs:subClassOf obo:NCBITaxon_2759 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#supplementary_motor_area_seizure> a rdfs:Class ;
  rdfs:label "supplementary motor area seizure" ;
  rdfs:seeAlso <http://www.case.edu/EpSO.owl#SupplementaryMotorAreaEpilepsy> ;
  rdfs:subClassOf <https://bio.scai.fraunhofer.de/ontology/epilepsy#frontal_lobe_seizure> .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#neocortical_epilepsy> a rdfs:Class ;
  rdfs:label "neocortical epilepsy" ;
  rdfs:subClassOf <https://bio.scai.fraunhofer.de/ontology/epilepsy#symptomatic_epilepsy> .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#breach_rhythm> a rdfs:Class ;
  rdfs:label "breach rhythm" ;
  rdfs:seeAlso <http://www.case.edu/EpSO.owl#BreachRhythm> ;
  rdfs:subClassOf <https://bio.scai.fraunhofer.de/ontology/epilepsy#epileptiform_benign_variant> .

obo:NCIT_C121351 a rdfs:Class ;
  rdfs:label "Occupational Therapy" ;
  rdfs:comment "Interventions and exercises intended to develop, recover, or maintain the ability of an individual to accomplish their activities of daily living." ;
  rdfs:seeAlso <https://www.epilepsy.com/learn/diagnosis/you-and-your-healthcare-team/rehabilitation-therapists> ;
  rdfs:subClassOf obo:NCIT_C15747 .

obo:MONDO_0021639 a rdfs:Class ;
  rdfs:label "grade II glioma" ;
  rdfs:comment "A glioma arising from the central nervous system. This category includes diffuse astrocytoma, ependymoma, oligodendroglioma, and oligoastrocytoma." ;
  rdfs:subClassOf obo:MONDO_0021637 .

obo:MP_0009642 a rdfs:Class ;
  rdfs:label "abnormal blood homeostasis" ;
  rdfs:comment "anomaly in the processes involved in the maintenance of an internal equilibrium of various functions or chemical or protein composition of the blood" ;
  rdfs:subClassOf obo:OGMS_0000037 .

obo:MP_0011723 a rdfs:Class ;
  rdfs:label "ectopic neuron" ;
  rdfs:comment "appearance of a neuron or group of neurons in a region where it is not normally found" ;
  rdfs:seeAlso <http://www.case.edu/EpSO.owl#NeuronalHeterotopia> ;
  rdfs:subClassOf obo:DOID_936 .

obo:SYMP_0000156 a rdfs:Class ;
  rdfs:label "thirst" ;
  rdfs:comment "Thirst is a general symptom characterized by a sensation of dryness in the mouth and throat associated with a desire for liquids." ;
  rdfs:subClassOf obo:SYMP_0000567 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#gamma_rhythm> a rdfs:Class ;
  rdfs:label "gamma rhythm" ;
  rdfs:subClassOf <https://bio.scai.fraunhofer.de/ontology/epilepsy#normal_EEG_pattern> .

obo:NCIT_C19021 a rdfs:Class ;
  rdfs:label "Rodent Model of Disease" ;
  rdfs:comment "A rodent disease whose pathologic mechanisms are sufficiently similar to those of a human disease to serve as a model." ;
  rdfs:subClassOf obo:NCIT_C71164 .

obo:HP_0100576 a rdfs:Class ;
  rdfs:label "Amaurosis fugax" ;
  rdfs:comment "A transient visual disturbance that is typically caused by a circulatory, ocular or neurological underlying condition." ;
  rdfs:subClassOf obo:HP_0000504 .

obo:SYMP_0000287 a rdfs:Class ;
  rdfs:label "arrhythmia" ;
  rdfs:comment "Arrhythmia is a cardiovascular system symptom consisting of an alteration in rhythm of the heartbeat either in time or force." ;
  rdfs:subClassOf obo:SYMP_0000528 .

obo:GO_0006936 a rdfs:Class ;
  rdfs:label "muscle contraction" ;
  rdfs:comment "A process in which force is generated within muscle tissue, resulting in a change in muscle geometry. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis." ;
  rdfs:subClassOf obo:GO_0003012 .

obo:DOID_3324 a rdfs:Class ;
  rdfs:label "mood disorder" ;
  rdfs:comment "A cognitive disorder that involves a disturbance in mood as the predominant underlying feature." ;
  rdfs:subClassOf obo:DOID_1561 .

obo:SYMP_0000597 a rdfs:Class ;
  rdfs:label "head and neck symptom" ;
  rdfs:subClassOf obo:SYMP_0000462 .

obo:HP_0031885 a rdfs:Class ;
  rdfs:label "Hyperglycorrhachia" ;
  rdfs:comment "Abnormally high glucose concentration in the cerebrospinal fluid." ;
  rdfs:subClassOf obo:HP_0031884 .

obo:HP_0000570 a rdfs:Class ;
  rdfs:label "Abnormal saccadic eye movements" ;
  rdfs:comment "An abnormality of eye movement characterized by impairment of fast (saccadic) eye movements." ;
  rdfs:subClassOf obo:HP_0000496 .

obo:DOID_14504 a rdfs:Class ;
  rdfs:label "Niemann-Pick disease" ;
  rdfs:comment "A sphingoliidosis characterized by the accumulation of the lipid sphingomyelin in lysosomes in cells." ;
  rdfs:seeAlso <https://www.epilepsy.com/learn/professionals/co-existing-disorders/metabolic-disorders/inborn-errors/niemann-pick-disease> ;
  rdfs:subClassOf obo:DOID_1927 .

obo:MFOEM_000009 a rdfs:Class ;
  rdfs:label "anger" ;
  rdfs:comment """Anger is a negative emotion, characterised by feelings of unpleasantness and high arousal, in the form of antagonistic feelings and action tendencies. [Source: OCEAS]
""" ;
  rdfs:subClassOf obo:MFOEM_000001 .

obo:NCBITaxon_7227 a rdfs:Class ;
  rdfs:label "Drosophila melanogaster" ;
  rdfs:subClassOf obo:NCBITaxon_6656 .

obo:MONDO_0009945 a rdfs:Class ;
  rdfs:label "pyridoxine-dependent epilepsy" ;
  rdfs:comment "Pyridoxine-dependent epilepsy (PDE) is a rare neurometabolic disease characterized by recurrent intractable seizures in the prenatal, neonatal and postnatal period that are resistant to anti-epileptic drugs (AEDs) but that are responsive to pharmacological dosages of pyridoxine (vitamin B6)." ;
  rdfs:subClassOf <https://bio.scai.fraunhofer.de/ontology/epilepsy#metabolic_etiology> .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#non-invasive_multichannel_magnetoencephalography> a rdfs:Class ;
  rdfs:label "non-invasive multichannel magnetoencephalography" ;
  rdfs:subClassOf <https://bio.scai.fraunhofer.de/ontology/epilepsy#non-invasive_preoperative_evaluation> .

obo:PATO_0000161 a rdfs:Class ;
  rdfs:label "rate" ;
  rdfs:comment "A quality of a single process inhering in a bearer by virtue of the bearer's occurrence per unit time." ;
  rdfs:subClassOf obo:PATO_0002062 .

obo:SYMP_0000892 a rdfs:Class ;
  rdfs:label "sensation perception" ;
  rdfs:comment "Sensation perception is a nervous system symptom where the information perceived by sensory receptors are interpreted." ;
  rdfs:subClassOf obo:SYMP_0000480 .

obo:OMIT_0006305 a rdfs:Class ;
  rdfs:label "Exercise Therapy" ;
  rdfs:seeAlso <https://www.betterhealth.vic.gov.au/health/ConditionsAndTreatments/epilepsy-and-exercise> ;
  rdfs:subClassOf obo:NCIT_C15315 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#focal_cognitive_seizure_with_receptive_dysphasia/aphasia> a rdfs:Class ;
  rdfs:label "focal cognitive seizure with receptive dysphasia/aphasia" ;
  rdfs:subClassOf <https://bio.scai.fraunhofer.de/ontology/epilepsy#focal_cognitive_seizure> .

obo:DOID_0060169 a rdfs:Class ;
  rdfs:label "benign familial infantile epilepsy" ;
  rdfs:comment "An infancy electroclinical syndrome that is characterized by convulsions, with onset at age 3 to 12 months." ;
  rdfs:subClassOf obo:MONDO_0015642 , obo:MONDO_0015654 .

obo:DOID_0060032 a rdfs:Class ;
  rdfs:label "autoimmune disease of musculoskeletal system" ;
  rdfs:comment "An autoimmune hypersensitivity disease that is the abnormal functioning of the immune system that causes your immune system to produce antibodies or T cells against cells and/or tissues in the musculoskeletal system." ;
  rdfs:subClassOf obo:DOID_17 , obo:DOID_417 .

obo:MONDO_0015659 a rdfs:Class ;
  rdfs:label "infectious disease with epilepsy" ;
  rdfs:subClassOf obo:DOID_1826 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#epileptic_encephalopathy_with_continous_spikes_and_wave_during_sleep> a rdfs:Class ;
  rdfs:label "epileptic encephalopathy with continous spikes and wave during sleep" ;
  rdfs:subClassOf obo:MONDO_0020072 .

obo:ERO_0001351 a rdfs:Class ;
  rdfs:label "single photon emission computed tomography" ;
  rdfs:comment "An imaging technique, in which a gamma camera rotates around the patient and takes pictures from many angles, and a tomographic (cross-sectional) image is generated." ;
  rdfs:subClassOf obo:ERO_0001312 .

obo:DOID_438 a rdfs:Class ;
  rdfs:label "autoimmune disease of the nervous system" ;
  rdfs:comment "An autoimmune hypersensitivity disease affecting the nervous system." ;
  rdfs:subClassOf obo:DOID_417 .

obo:SYMP_0019182 a rdfs:Class ;
  rdfs:label "behavioral symptom" ;
  rdfs:comment "A nervous system symptom that involves, is related to, or emphasizes behavior." ;
  rdfs:subClassOf obo:SYMP_0000480 .

obo:HP_0011450 a rdfs:Class ;
  rdfs:label "Unusual CNS infection" ;
  rdfs:comment "A type of infection of the central nervous system that can be regarded as a sign of a pathological susceptibility to infection." ;
  rdfs:subClassOf obo:HP_0002011 .

obo:DOID_0050990 a rdfs:Class ;
  rdfs:label "episodic ataxia type 2" ;
  rdfs:comment "An episodic ataxia that is characterized by periodic ataxia and nystagmus, and has_material_basis_in autosomal dominant inheritance of mutation in the calcium channel gene CACNA1A." ;
  rdfs:subClassOf obo:DOID_963 .

obo:UBERON_0000093 a rdfs:Class ;
  rdfs:label "sulcus" ;
  rdfs:comment "A depression or fissure in the surface of an organ." ;
  rdfs:subClassOf obo:UBERON_0000464 .

obo:MONDO_0000839 a rdfs:Class ;
  rdfs:label "congenital abnormality" ;
  rdfs:comment "Any abnormality, anatomical or biochemical, evident at birth or during the neonatal period." ;
  rdfs:subClassOf obo:DOID_4 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#parahippocampal_epilepsy> a rdfs:Class ;
  rdfs:label "parahippocampal epilepsy" ;
  rdfs:seeAlso <http://www.case.edu/EpSO.owl#ParaHippocampalEpilepsy> ;
  rdfs:subClassOf obo:DOID_3328 .

obo:UBERON_0013552 a rdfs:Class ;
  rdfs:label "Brodmann (1909) area 21" ;
  rdfs:comment "Brodmann area 21, or BA21, is part of the temporal cortex in the human brain. The region encompasses most of the lateral temporal cortex, a region believed to play a part in auditory processing and language. Language function is left lateralized in most individuals. BA21 is superior to BA20 and inferior to BA40 and BA41. This area is also known as middle temporal area 21. It is a subdivision of the cytoarchitecturally defined temporal region of cerebral cortex. In the human it corresponds approximately to the middle temporal gyrus. It is bounded rostrally by the temporopolar area 38 (H), ventrally by the inferior temporal area 20, caudally by the occipitotemporal area 37 (H), and dorsally by the superior temporal area 22 (Brodmann-1909). [WP,unvetted]." ;
  rdfs:subClassOf obo:UBERON_0013529 .

obo:HP_0002266 a rdfs:Class ;
  rdfs:label "Focal clonic seizure" ;
  rdfs:comment "A focal clonic seizure is a type of focal motor seizure characterized by sustained rhythmic jerking, that is regularly repetitive." ;
  rdfs:seeAlso <http://www.medlink.com/article/focal_clonic_seizures> ;
  rdfs:subClassOf obo:HP_0011153 .

obo:UBERON_0000957 a rdfs:Class ;
  rdfs:label "lamina" ;
  rdfs:comment "Any thin layer or plate." ;
  rdfs:subClassOf obo:UBERON_0000479 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#mesial_temporal_lobe_epilepsy_by_specific_etiology> a rdfs:Class ;
  rdfs:label "mesial temporal lobe epilepsy by specific etiology" ;
  rdfs:subClassOf <https://bio.scai.fraunhofer.de/ontology/epilepsy#limbic_epilepsy> .

obo:ERO_0000833 a rdfs:Class ;
  rdfs:label "molecular assay" ;
  rdfs:comment "An assay that generates data about the presence, abundance, structure, function, or activity of biological molecules, or a process that occurs at a molecular level of granularity." ;
  rdfs:subClassOf obo:OBI_0000070 .

obo:UBERON_0035014 a rdfs:Class ;
  rdfs:label "functional part of brain" ;
  rdfs:comment "A brain region defined by functional criteria, e.g. auditory cortex, rather than by structural or histological criteria." ;
  rdfs:subClassOf obo:UBERON_0002616 .

obo:HP_0025357 a rdfs:Class ;
  rdfs:label "Erratic myoclonus" ;
  rdfs:comment "A type of myoclonus in which the myoclonias shift from body region to another in a random and asynchronous fashion. Erratic myoclonus can affect the face or limbs, are brief, single or repetitive, very frequent and nearly continuous." ;
  rdfs:subClassOf obo:HP_0001336 .

obo:DOID_850 a rdfs:Class ;
  rdfs:label "lung disease" ;
  rdfs:comment "A lower respiratory tract disease in which the function of the lungs is adversely affected by narrowing or blockage of the airways resulting in poor air flow, a loss of elasticity in the lungs that produces a decrease in the total volume of air that the lungs are able to hold, and clotting, scarring, or inflammation of the blood vessels that affect the ability of the lungs to take up oxygen and to release carbon dioxide." ;
  rdfs:subClassOf obo:DOID_0050161 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#non-pharmacological_treatment_of_epilepsy> a rdfs:Class ;
  rdfs:label "non-pharmacological treatment of epilepsy" ;
  rdfs:subClassOf obo:OGMS_0000090 .

obo:UBERON_0002912 a rdfs:Class ;
  rdfs:label "marginal sulcus" ;
  rdfs:comment "The marginal sulcus is the portion of the cingulate sulcus adjacent to the paracentral lobule and the precuneus. It is sometimes known as the 'marginal part of the cingulate sulcus'. [WP,unvetted]." ;
  rdfs:subClassOf obo:UBERON_0008334 .

obo:DOID_1074 a rdfs:Class ;
  rdfs:label "kidney failure" ;
  rdfs:comment "A kidney disease characterized by the failure of the kidneys to adequately filter waste products from the blood." ;
  rdfs:subClassOf obo:DOID_557 .

obo:OMIT_0028745 a rdfs:Class ;
  rdfs:label "Gamma Rhythm" ;
  rdfs:subClassOf obo:OMIT_0027154 .

obo:SYMP_0000414 a rdfs:Class ;
  rdfs:label "dysarthria" ;
  rdfs:comment "Dysarthria is a neurological and physiological symptom characterized by a difficulty in articulating words due to disease of the central nervous system." ;
  rdfs:subClassOf obo:SYMP_0000410 .

obo:HP_0020220 a rdfs:Class ;
  rdfs:label "Focal atonic seizure" ;
  rdfs:comment "A focal seizure characterized at onset by sudden loss or diminution of muscle tone without apparent preceding myoclonic or tonic activity, typically lasting more than 500 ms but less than 2 seconds. It may involve the head, trunk, jaw or limb musculature." ;
  rdfs:seeAlso <https://www.epilepsy.com/learn/types-seizures/atonic-seizures> ;
  rdfs:subClassOf obo:HP_0011153 .

obo:NCIT_C160587 a rdfs:Class ;
  rdfs:label "Executive Function Disorder" ;
  rdfs:comment "Cognitive, emotional, and behavioral difficulties that often occur in conjunction with frontal lobe disorders, including traumatic injury and dementia. It is also a feature of attention deficit disorder and other non-trauma-induced conditions." ;
  rdfs:subClassOf obo:DOID_1561 .

obo:HP_0032661 a rdfs:Class ;
  rdfs:label "Generalized convulsive status epilepticus" ;
  rdfs:comment "A type of bilateral convulsive seizure of generalized onset that is sufficiently prolonged (or repeated without recovery) to reach the threshold for status epilepticus." ;
  rdfs:subClassOf obo:HP_0032660 .

obo:GO_0042703 a rdfs:Class ;
  rdfs:label "menstruation" ;
  rdfs:comment "The cyclic, physiologic discharge through the vagina of blood and endometrial tissues from the nonpregnant uterus." ;
  rdfs:subClassOf obo:GO_0022601 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#positive_visual_hallucination> a rdfs:Class ;
  rdfs:label "positive visual hallucination" ;
  rdfs:subClassOf obo:NBO_0000609 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#alpha_coma> a rdfs:Class ;
  rdfs:label "alpha coma" ;
  rdfs:seeAlso <http://www.case.edu/EpSO.owl#AlphaComa> ;
  rdfs:subClassOf <https://bio.scai.fraunhofer.de/ontology/epilepsy#special_pattern> .

obo:NCIT_C93013 a rdfs:Class ;
  rdfs:label "3 Tesla Magnetic Resonance Imaging" ;
  rdfs:comment "MRI that uses a magnet capable of producing a 3 telsa field strength. In theory, 3.0 T magnets have the capability to provide better image quality, with improved diagnostic performance." ;
  rdfs:subClassOf obo:ERO_0001235 .

obo:HP_0032055 a rdfs:Class ;
  rdfs:label "Focal cortical dysplasia type IIIa" ;
  rdfs:comment "A subtype of focal cortical dysplasia type III that is characterized by alterations in architectural organisation (cortical dyslamination) or cytoarchitectural composition (hypertrophic neurons outside Layer 5) in patients with hippocampal sclerosis (HS, syn. Ammon's horn sclerosis)." ;
  rdfs:seeAlso <http://www.case.edu/EpSO.owl#FocalCorticalDysplasiaTypeIIIA> ;
  rdfs:subClassOf obo:HP_0032054 .

obo:DOID_535 a rdfs:Class ;
  rdfs:label "sleep disorder" ;
  rdfs:comment "A disease of mental health that involves disruption of sleep patterns." ;
  rdfs:seeAlso <http://www.case.edu/EpSO.owl#SleepDisorder> , <https://www.epilepsy.com/learn/professionals/co-existing-disorders/sleep-disorders> ;
  rdfs:subClassOf <https://bio.scai.fraunhofer.de/ontology/epilepsy#epilepsy_imitator> .

obo:NCIT_C68680 a rdfs:Class ;
  rdfs:label "Laser Interstitial Thermal Therapy" ;
  rdfs:comment "A thermal ablation therapy in which neoplasms are heated with prolonged and moderate temperature elevations.  It results in coagulative necrosis in the heated tissue." ;
  rdfs:subClassOf obo:OGMS_0000112 .

obo:MONDO_0016608 a rdfs:Class ;
  rdfs:label "megalencephaly (disease)" ;
  rdfs:comment "A congenital abnormality in which the occipitofrontal circumference is greater than two standard deviations above the mean for a given age. It is associated with hydrocephalus; subdural effusion; arachnoid cysts; or is part of a genetic condition (e.g., alexander disease; sotos syndrome)." ;
  rdfs:seeAlso <http://www.case.edu/EpSO.owl#Megalencephaly> ;
  rdfs:subClassOf obo:DOID_936 .

obo:UBERON_0002771 a rdfs:Class ;
  rdfs:label "middle temporal gyrus" ;
  rdfs:comment "Component of the temporal lobe, lateral aspect. The rostral boundary is the rostral extent of the superior temporal sulcus whereas the caudal boundary is the temporo-occipital incisure on the cortical surface. The superior temporal sulcus is the medial boundary and the inferior temporal sulcus is the lateral boundary (Christine Fennema-Notestine)." ;
  rdfs:subClassOf obo:UBERON_0000200 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#lethargic_mouse> a rdfs:Class ;
  rdfs:label "lethargic mouse" ;
  rdfs:subClassOf <https://bio.scai.fraunhofer.de/ontology/epilepsy#absence_seizure_model> .

obo:MONDO_0005433 a rdfs:Class ;
  rdfs:label "alcohol withdrawal" ;
  rdfs:subClassOf obo:MONDO_0005567 .

obo:MONDO_0019485 a rdfs:Class ;
  rdfs:label "idiopathic hemiconvulsion-hemiplegia syndrome" ;
  rdfs:seeAlso <https://www.medlink.com/index.php/article/hemiconvulsion-hemiplegia-epilepsy_syndrome> ;
  rdfs:subClassOf obo:DOID_225 , obo:MONDO_0018200 .

obo:OGMS_0000029 a rdfs:Class ;
  rdfs:label "vital sign" ;
  rdfs:comment "A physical sign in which a non-zero value is standardly considered to be an indication that the organism is alive." ;
  rdfs:subClassOf obo:OGMS_0000024 .

obo:OMIT_0026330 a rdfs:Class ;
  rdfs:label "Vagus Nerve Stimulation" ;
  rdfs:subClassOf obo:OGMS_0000112 .

obo:DOID_8893 a rdfs:Class ;
  rdfs:label "psoriasis" ;
  rdfs:comment "A skin disease that is characterized by patches of thick red skin and silvery scales." ;
  rdfs:subClassOf obo:DOID_37 .

obo:ERO_0001830 a rdfs:Class ;
  rdfs:label "positron emission tomography" ;
  rdfs:comment "An imaging technique that produces a three-dimensional image or picture of functional processes in the body. The system detects pairs of gamma rays emitted indirectly by a positron-emitting radionuclide (tracer), which is introduced into the body on a biologically active molecule. Three-dimensional images of tracer concentration within the body are then constructed by computer analysis." ;
  rdfs:subClassOf obo:ERO_0001312 .

obo:ERO_0000347 a rdfs:Class ;
  rdfs:label "intervention" ;
  rdfs:comment "A planned process used to influence one or more factors in a research study, and the independent variable in an interventional study wherein the influence is measured or evaluated." ;
  rdfs:subClassOf obo:OBI_0000011 .

obo:GO_0007613 a rdfs:Class ;
  rdfs:label "memory" ;
  rdfs:comment "The activities involved in the mental information processing system that receives (registers), modifies, stores, and retrieves informational stimuli. The main stages involved in the formation and retrieval of memory are encoding (processing of received information by acquisition), storage (building a permanent record of received information as a result of consolidation) and retrieval (calling back the stored information and use it in a suitable way to execute a given task)." ;
  rdfs:subClassOf obo:MF_0000033 .

obo:DOID_5078 a rdfs:Class ;
  rdfs:label "ganglioglioma" ;
  rdfs:comment "A cell type benign neoplasm that has_material_basis_in glial-type cells." ;
  rdfs:seeAlso <http://www.case.edu/EpSO.owl#Ganglioglioma> ;
  rdfs:subClassOf obo:HP_0002664 .

obo:UBERON_0006484 a rdfs:Class ;
  rdfs:label "Brodmann (1909) area 47" ;
  rdfs:comment "Brodmann area 47, or BA47, is part of the frontal cortex in the human brain. Curving from the lateral surface of the frontal lobe into the ventral (orbital) frontal cortex. It is below areas BA10 and BA45, and beside BA11. This area is also known as orbital area 47. In the human, on the orbital surface it surrounds the caudal portion of the orbital sulcus (H) from which it extends laterally into the orbital part of inferior frontal gyrus (H). Cytoarchitectonically it is bounded caudally by the triangular area 45, medially by the prefrontal area 11 of Brodmann-1909, and rostrally by the frontopolar area 10 (Brodmann-1909). It incorporates the region that Brodmann identified as 'Area 12' in the monkey, and therefore, following the suggestion of Michael Petrides, some contemporary neuroscientists refer to the region as 'BA47/12. ' BA47 has been implicated in the processing of syntax in spoken and signed languages, and more recently in musical syntax." ;
  rdfs:subClassOf obo:UBERON_0013529 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#midline_theta_rhythm> a rdfs:Class ;
  rdfs:label "midline theta rhythm" ;
  rdfs:seeAlso <http://www.case.edu/EpSO.owl#MidlineThetaRhythm> ;
  rdfs:subClassOf <https://bio.scai.fraunhofer.de/ontology/epilepsy#rhythmic_benign_variant> .

obo:NCIT_C116664 a rdfs:Class ;
  rdfs:label "Electrocorticography" ;
  rdfs:comment "The use of electrodes placed directly on the exposed brain surface to record the electrical activity of the cerebral cortex." ;
  rdfs:subClassOf obo:ERO_0001292 .

obo:UBERON_0000344 a rdfs:Class ;
  rdfs:label "mucosa" ;
  rdfs:comment "A lining of mostly endodermal origin, covered in epithelium, which is involved in absorption and secretion. They line various body cavities that are exposed to the external environment and internal organs. It is at several places continuous with skin: at the nostrils, the lips, the ears, the genital area, and the anus. The sticky, thick fluid secreted by the mucous membranes and gland is termed mucus. The term mucous membrane refers to where they are found in the body and not every mucous membrane secretes mucus[WP]" ;
  rdfs:subClassOf obo:UBERON_0004923 .

obo:UBERON_0002562 a rdfs:Class ;
  rdfs:label "superior frontal sulcus" ;
  rdfs:comment "The superior frontal sulcus is a sulcus between the superior frontal gyrus and the middle frontal gyrus. [WP,unvetted]." ;
  rdfs:subClassOf obo:UBERON_0013118 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#focal_sensory_vestibular_seizure> a rdfs:Class ;
  rdfs:label "focal sensory vestibular seizure" ;
  rdfs:seeAlso <https://link.springer.com/chapter/10.1007/978-1-4757-3801-8_14> ;
  rdfs:subClassOf obo:HP_0011157 .

obo:NCIT_C63479 a rdfs:Class ;
  rdfs:label "Gene Expression Analysis" ;
  rdfs:subClassOf obo:NCIT_C19770 .

obo:DOID_3488 a rdfs:Class ;
  rdfs:label "cellulitis" ;
  rdfs:comment "A skin disease where there is a diffuse infection of connective tissue with severe inflammation of dermal and subcutaneous layers of the skin. Cellulitis can be caused by normal skin flora or by exogenous bacteria, and often occurs where the skin has previously been broken: cracks in the skin, cuts, blisters, burns, insect bites, surgical wounds, or sites of intravenous catheter insertion." ;
  rdfs:subClassOf obo:DOID_37 , obo:DOID_65 .

obo:SYMP_0000022 a rdfs:Class ;
  rdfs:label "depression" ;
  rdfs:seeAlso <http://www.case.edu/EpSO.owl#Depression> , <https://www.epilepsy.com/living-epilepsy/healthy-living/emotional-health/overview-depression> ;
  rdfs:subClassOf obo:DOID_2468 .

obo:NCIT_C86933 a rdfs:Class ;
  rdfs:label "Unresponsive" ;
  rdfs:comment "Failing to produce an effect from some foregoing stimulus or agent." ;
  rdfs:subClassOf obo:PATO_0001995 .

obo:DOID_1579 a rdfs:Class ;
  rdfs:label "respiratory system disease" ;
  rdfs:comment "A disease of anatomical entity that located_in the respiratory system which extends from the nasal sinuses to the diaphragm." ;
  rdfs:subClassOf obo:DOID_7 .

obo:HP_0011162 a rdfs:Class ;
  rdfs:label "Psychic auras" ;
  rdfs:comment "Auras with affective, mnemonic or composite perceptual phenomena including illusory or composite hallucinatory events." ;
  rdfs:seeAlso <http://www.case.edu/EpSO.owl#PsychicAura> ;
  rdfs:subClassOf obo:SYMP_0000124 .

obo:RS_0000969 a rdfs:Class ;
  rdfs:label "WAG/Rij" ;
  rdfs:subClassOf obo:RS_0000765 .

obo:MONDO_0020067 a rdfs:Class ;
  rdfs:label "infectious encephalitis" ;
  rdfs:comment "An acute infectious process that affects the brain tissue. It is usually caused by viruses and less often by bacteria, parasites, and fungi." ;
  rdfs:subClassOf obo:DOID_9588 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#hyperthermic_seizure_model> a rdfs:Class ;
  rdfs:label "hyperthermic seizure model" ;
  rdfs:subClassOf obo:NCIT_C19021 .

obo:CMO_0000296 a rdfs:Class ;
  rdfs:label "abdominal morphological measurement" ;
  rdfs:subClassOf obo:CMO_0000021 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#chemical_mutagenesis_derived_model> a rdfs:Class ;
  rdfs:label "chemical mutagenesis derived model" ;
  rdfs:subClassOf obo:NCIT_C19272 .

obo:HP_0002011 a rdfs:Class ;
  rdfs:label "Morphological abnormality of the central nervous system" ;
  rdfs:comment "A structural abnormality of the central nervous system." ;
  rdfs:subClassOf obo:HP_0012639 .

obo:HP_0000496 a rdfs:Class ;
  rdfs:label "Abnormality of eye movement" ;
  rdfs:comment "An abnormality in voluntary or involuntary eye movements or their control." ;
  rdfs:subClassOf obo:HP_0012373 .

obo:MONDO_0043264 a rdfs:Class ;
  rdfs:label "post-traumatic epilepsy" ;
  rdfs:comment "Recurrent seizures causally related to CRANIOCEREBRAL TRAUMA. Seizure onset may be immediate but is typically delayed for several days after the injury and may not occur for up to two years. The majority of seizures have a focal onset that correlates clinically with the site of brain injury. Cerebral cortex injuries caused by a penetrating foreign object (CRANIOCEREBRAL TRAUMA, PENETRATING) are more likely than closed head injuries (HEAD INJURIES, CLOSED) to be associated with epilepsy. Concussive convulsions are nonepileptic phenomena that occur immediately after head injury and are characterized by tonic and clonic movements. (From Rev Neurol 1998 Feb;26(150):256-261; Sports Med 1998 Feb;25(2):131-6)" ;
  rdfs:subClassOf obo:DOID_1826 .

obo:DOID_11335 a rdfs:Class ;
  rdfs:label "sarcoidosis" ;
  rdfs:comment "A hypersensitivity reaction type IV disease characterized by the growth of collections of inflammatory cells (granulomas) in multiple organs." ;
  rdfs:seeAlso <https://www.epilepsy.com/learn/professionals/co-existing-disorders/inflammatory-disorders> ;
  rdfs:subClassOf obo:DOID_2916 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#dominant_parieto-temporal_region_seizure> a rdfs:Class ;
  rdfs:label "dominant parieto-temporal region seizure" ;
  rdfs:subClassOf <https://bio.scai.fraunhofer.de/ontology/epilepsy#parietal_lobe_seizure> .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#focal_cognitive_seizure_with_left-right_confusion> a rdfs:Class ;
  rdfs:label "focal cognitive seizure with left-right confusion" ;
  rdfs:subClassOf <https://bio.scai.fraunhofer.de/ontology/epilepsy#focal_cognitive_seizure> .

obo:MF_0000059 a rdfs:Class ;
  rdfs:label "daydreaming" ;
  rdfs:comment "Short-term detachment from one's immediate surroundings, during which a person's contact with reality is blurred and partially substituted by a visionary fantasy, especially one of happy, pleasant thoughts, hopes or ambitions, imagined as coming to pass, and experienced while awake." ;
  rdfs:subClassOf obo:NCIT_C35470 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#migraine_associated_disorder> a rdfs:Class ;
  rdfs:label "migraine associated disorder" ;
  rdfs:seeAlso <https://www.epilepsydiagnosis.org/epilepsy-imitators.html#migraine> , <https://americanmigrainefoundation.org/resource-library/migraine-and-common-co-morbidities/> ;
  rdfs:subClassOf <https://bio.scai.fraunhofer.de/ontology/epilepsy#epilepsy_imitator> .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#inhibitory_motor_seizure> a rdfs:Class ;
  rdfs:label "inhibitory motor seizure" ;
  rdfs:subClassOf obo:SYMP_0000124 .

obo:DOID_3565 a rdfs:Class ;
  rdfs:label "meningioma" ;
  rdfs:comment "A central nervous system cancer that are manifested in the central nervous system and arise from the arachnoid cap cells of the arachnoid villi in the meninges." ;
  rdfs:seeAlso <http://www.case.edu/EpSO.owl#Meningioma> ;
  rdfs:subClassOf obo:DOID_3620 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#hippocampal_kindling_model> a rdfs:Class ;
  rdfs:label "hippocampal kindling model" ;
  rdfs:subClassOf obo:OMIT_0008800 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#4-aminopyridine_slice_model> a rdfs:Class ;
  rdfs:label "4-aminopyridine slice model" ;
  rdfs:subClassOf obo:NCIT_C19146 .

obo:DOID_0050589 a rdfs:Class ;
  rdfs:label "inflammatory bowel disease" ;
  rdfs:comment "An intestinal disease characterized by inflammation located_in all parts of digestive tract." ;
  rdfs:subClassOf obo:DOID_5295 .

obo:NBO_0000705 a rdfs:Class ;
  rdfs:label "automatism" ;
  rdfs:comment "\"Purposeless repetitive motor activities that often occur during a seizure.\" [NBO:GVG]" ;
  rdfs:subClassOf obo:NBO_0000643 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#extra_striate_cortex_seizure> a rdfs:Class ;
  rdfs:label "extra striate cortex seizure" ;
  rdfs:subClassOf <https://bio.scai.fraunhofer.de/ontology/epilepsy#occipital_lobe_seizure> .

obo:MONDO_0020310 a rdfs:Class ;
  rdfs:label "familial focal epilepsy with variable foci" ;
  rdfs:comment "Familial focal epilepsy with variable foci is a rare genetic epilepsy disorder characterized by autosomal dominant lesional and nonlesional focal epilepsy with variable penetrance. Focal seizures emanate from different cortical locations (temporal, frontal, centroparietal, parietal, parietaloccipital, occipital) in different family members, but for each individual a single focus remains constant throughout lifetime. Seizure type (tonic, tonic-clonic or hyperkinetic) and severity varies among family members and tends to decrease (but do not disappear) during adulthood. Many patients have an aura and show automatisms during diurnal seizures whereas others have nocturnal seizures. Most individuals are of normal intelligence but patients with intellectual disability, autistic spectrum disorder and obsessive-compulsive disorder have been described." ;
  rdfs:subClassOf obo:MONDO_0100036 .

obo:UBERON_0001896 a rdfs:Class ;
  rdfs:label "medulla oblongata" ;
  rdfs:comment "Organ component of neuraxis that has as its parts the medullary reticular formation, inferior olivary complex and cochlear nuclear complex, among other structures[FMA]. The medulla oblongata lies directly above the spinal cord and controls vital autonomic functions such as digestion, breathing and the control of heart rate[GO]." ;
  rdfs:subClassOf obo:UBERON_0000064 .

obo:NCBITaxon_10047 a rdfs:Class ;
  rdfs:label "Meriones unguiculatus" ;
  rdfs:subClassOf obo:NCBITaxon_9989 .

obo:PATO_0001236 a rdfs:Class ;
  rdfs:label "process quality" ;
  rdfs:comment "A quality which inheres in an process." ;
  rdfs:subClassOf obo:BFO_0000019 .

obo:MP_0001340 a rdfs:Class ;
  rdfs:label "abnormal eyelid morphology" ;
  rdfs:comment "any structural anomaly of the skin folds covering the front of the eyeball" ;
  rdfs:subClassOf obo:HP_0012372 .

obo:MFOMD_0000136 a rdfs:Class ;
  rdfs:label "panic attack" ;
  rdfs:comment """Period of intense fear or apprehension that are of sudden onset and of variable duration from minutes to hours.


http://en.wikipedia.org/wiki/Panic_attack""" ;
  rdfs:subClassOf obo:NCIT_C35470 .

obo:OAE_0002392 a rdfs:Class ;
  rdfs:label "brain injury AE" ;
  rdfs:comment "a brain injury AE,  injury to the brain caused by an external force, that results in a brain AE" ;
  rdfs:seeAlso <http://www.case.edu/EpSO.owl#TraumaticBrainInjury> , <https://www.epilepsydiagnosis.org/aetiology/traumatic-brain-injury-overview.html> ;
  rdfs:subClassOf <https://bio.scai.fraunhofer.de/ontology/epilepsy#structural_etiology> .

obo:NCIT_C25499 a rdfs:Class ;
  rdfs:label "Event" ;
  rdfs:comment "Something that happens at a given place and time." ;
  rdfs:subClassOf obo:BFO_0000015 .

<https://bio.scai.fraunhofer.de/ontology/0000413> a rdfs:Class ;
  rdfs:label "seizure classification TM_BIN" ;
  rdfs:comment "The 'seizure classification TM_BIN' concept enables a compilation of diverse concepts that are related to seizure classification in Epilepsy via the Axiome 'isSeizureClassificationFor some epilepsy'.  Thus enables the adaptation of the ontology for text mining purposes for Epilepsy related information retrieval and information extraction." .

obo:UBERON_0003947 a rdfs:Class ;
  rdfs:label "brain ventricle/choroid plexus" ;
  rdfs:comment "The brain ventricles or their associated choroid plexuses" ;
  rdfs:subClassOf obo:UBERON_0010000 .

obo:OGMS_0000018 a rdfs:Class ;
  rdfs:label "laboratory finding" ;
  rdfs:comment "A representation of a quality of a specimen that is the output of a laboratory test and that can support an inference to an assertion about some quality of the patient." ;
  rdfs:subClassOf obo:OGMS_0000014 .

obo:DOID_6364 a rdfs:Class ;
  rdfs:label "migraine" ;
  rdfs:comment "A brain disease that is characterized by moderate to severe headaches, nausea, extreme sensitivity to light and sound and intense unilaterial throbbing or pulsing." ;
  rdfs:seeAlso <https://www.epilepsy.com/learn/professionals/co-existing-disorders/migraine-epilepsy> ;
  rdfs:subClassOf obo:DOID_936 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#spark> a rdfs:Class ;
  rdfs:label "spark" ;
  rdfs:seeAlso <https://www.scientificamerican.com/article/brains-gilal-cells-spark-seizures/> ;
  rdfs:subClassOf <https://bio.scai.fraunhofer.de/ontology/epilepsy#positive_visual_hallucination> .

obo:HP_0001892 a rdfs:Class ;
  rdfs:label "Abnormal bleeding" ;
  rdfs:comment "An abnormal susceptibility to bleeding, often referred to as a bleeding diathesis. A bleeding diathesis may be related to vascular, platelet and coagulation defects." ;
  rdfs:subClassOf obo:HP_0001871 .

obo:NBO_0000504 a rdfs:Class ;
  rdfs:label "REM parasomnia" ;
  rdfs:comment "\"A type of parasomnia that occurs during REM sleep.\" [NBO:GVG]" ;
  rdfs:subClassOf obo:NBO_0000419 .

obo:HP_0100659 a rdfs:Class ;
  rdfs:label "Abnormality of the cerebral vasculature" ;
  rdfs:subClassOf obo:HP_0002597 , obo:HP_0012443 .

obo:MONDO_0019113 a rdfs:Class ;
  rdfs:label "benign paroxysmal torticollis of infancy" ;
  rdfs:comment "Benign paroxysmal torticollis of infancy (BPTI) is a rare functional disorder characterised by recurrent episodes of torticollic posturing of the head (inclination or tilting of the head to one side) in healthy children." ;
  rdfs:subClassOf <https://bio.scai.fraunhofer.de/ontology/epilepsy#migraine_associated_disorder> .

obo:DOID_5614 a rdfs:Class ;
  rdfs:label "eye disease" ;
  rdfs:comment "An eye and adnexa disease that is located_in the eye." ;
  rdfs:subClassOf obo:DOID_0050155 .

<https://bio.scai.fraunhofer.de/ontology/0000502> a rdfs:Class ;
  rdfs:label "brain functional connectivity" ;
  rdfs:subClassOf <https://bio.scai.fraunhofer.de/ontology/0000501> .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#quality_of_life_in_epilepsy_inventory_-_89> a rdfs:Class ;
  rdfs:label "quality of life in epilepsy inventory - 89" ;
  rdfs:subClassOf obo:NCIT_C20993 .

obo:DOID_3342 a rdfs:Class ;
  rdfs:label "bone inflammation disease" ;
  rdfs:comment "A bone disease that results_in inflammation of the located_in bone." ;
  rdfs:subClassOf obo:DOID_0080001 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#audiogenic_model> a rdfs:Class ;
  rdfs:label "audiogenic model" ;
  rdfs:subClassOf obo:NCIT_C19272 .

obo:NCIT_C36327 a rdfs:Class ;
  rdfs:label "Gene Abnormality" ;
  rdfs:comment "A variation in or modification of the nucleic acid sequence of a gene that can alter its expression and may result in either a congenital disorder or the clinical presentation of a disease." ;
  rdfs:seeAlso <http://www.case.edu/EpSO.owl#GeneticMutation> ;
  rdfs:subClassOf <https://bio.scai.fraunhofer.de/ontology/epilepsy#genetic_etiology> .

obo:BFO_0000019 a rdfs:Class ;
  rdfs:label "quality" ;
  rdfs:subClassOf obo:BFO_0000020 .

obo:DOID_6000 a rdfs:Class ;
  rdfs:label "congestive heart failure" ;
  rdfs:comment "A heart disease that is characterized by any structural or functional cardiac disorder that impairs the ability of the heart to fill with or pump a sufficient amount of blood throughout the body." ;
  rdfs:seeAlso <https://www.epilepsy.com/learn/professionals/co-existing-disorders/cardiac-disorders> ;
  rdfs:subClassOf obo:DOID_114 .

<https://bio.scai.fraunhofer.de/ontology/0000514> a rdfs:Class ;
  rdfs:label "intracranial electrode" ;
  rdfs:subClassOf obo:NCIT_C49936 .

obo:DOID_9588 a rdfs:Class ;
  rdfs:label "encephalitis" ;
  rdfs:comment "A brain disease that is characterized as an acute inflammation of the brain with flu-like symptoms." ;
  rdfs:seeAlso <http://www.case.edu/EpSO.owl#Encephalitis> ;
  rdfs:subClassOf obo:DOID_936 .

obo:HP_0002349 a rdfs:Class ;
  rdfs:label "Focal aware seizure" ;
  rdfs:comment "A type of focal-onset seizure in which awareness is preserved. Awareness during a seizure is defined as the patient being fully aware of themself and their environment throughout the seizure, even if immobile." ;
  rdfs:subClassOf <https://bio.scai.fraunhofer.de/ontology/epilepsy#focal_seizure_classification_by_onset_feature> .

obo:NCIT_C121459 a rdfs:Class ;
  rdfs:label "Behavior Rating Inventory of Executive Function" ;
  rdfs:comment "A standardized rating scale designed to assess the executive function behaviors in the school and home environments for children and adolescents as observed by a parent or teacher." ;
  rdfs:subClassOf obo:NCIT_C20993 .

obo:HP_0020219 a rdfs:Class ;
  rdfs:label "Motor seizure" ;
  rdfs:comment "A motor seizure is a type of seizure that is characterized at onset by involvement of the skeletal musculature. The motor event could consist of an increase (positive) or decrease (negative) in muscle contraction to produce a movement." ;
  rdfs:subClassOf obo:SYMP_0000124 .

obo:DOID_0060500 a rdfs:Class ;
  rdfs:label "drug allergy" ;
  rdfs:comment "A hypersensitivity reaction type I disease triggered by a drug." ;
  rdfs:subClassOf obo:DOID_1205 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#ictal_or_post-ictal_respiratory_abnormality> a rdfs:Class ;
  rdfs:label "ictal or post-ictal respiratory abnormality" ;
  rdfs:subClassOf obo:SYMP_0000514 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#artifact_obscured_EEG> a rdfs:Class ;
  rdfs:label "artifact obscured EEG" ;
  rdfs:seeAlso <http://www.case.edu/EpSO.owl#ArtifactObscuredEEG> ;
  rdfs:subClassOf obo:HP_0025373 .

obo:ERO_0000606 a rdfs:Class ;
  rdfs:label "psychological and behavioral intervention" ;
  rdfs:comment "Psychological or behavior intervention is a combination of program elements, strategies, or modalities designed to influence psychological or behavioral processes or outcomes." ;
  rdfs:subClassOf obo:OBI_0000011 .

obo:GO_0009987 a rdfs:Class ;
  rdfs:label "cellular process" ;
  rdfs:comment "Any process that is carried out at the cellular level, but not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level." ;
  rdfs:subClassOf obo:GO_0008150 .

obo:MF_0000013 a rdfs:Class ;
  rdfs:label "thinking" ;
  rdfs:comment "a mental process that involves the manipulation of mental language and/or mental images" ;
  rdfs:seeAlso <https://www.epilepsy.com/learn/challenges-epilepsy/thinking-and-memory> ;
  rdfs:subClassOf obo:MF_0000020 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#cingulate_cortex_seizure> a rdfs:Class ;
  rdfs:label "cingulate cortex seizure" ;
  rdfs:subClassOf <https://bio.scai.fraunhofer.de/ontology/epilepsy#frontal_lobe_seizure> .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#non-invasive_assessment_of_language_dominance> a rdfs:Class ;
  rdfs:label "non-invasive assessment of language dominance" ;
  rdfs:subClassOf obo:NCIT_C20993 .

obo:MONDO_0011593 a rdfs:Class ;
  rdfs:label "seizures, benign familial infantile, 2" ;
  rdfs:subClassOf obo:DOID_0060169 .

obo:HP_0010821 a rdfs:Class ;
  rdfs:label "Gelastic seizures" ;
  rdfs:comment "A type of seizure characterized by laughing or an outburst of laughing as a major feature." ;
  rdfs:seeAlso <http://www.case.edu/EpSO.owl#GelasticSeizure> , <https://www.epilepsy.com/learn/types-seizures/gelastic-and-dacrystic-seizures> ;
  rdfs:subClassOf obo:HP_0025613 .

obo:HP_0012004 a rdfs:Class ;
  rdfs:label "Mnemonic auras" ;
  rdfs:comment "Auras which reflect ictal dysmnesia such as: feelings as familiarity (deja-vu) and unfamiliarity (jamais-vu)." ;
  rdfs:subClassOf obo:HP_0012002 .

obo:HP_0000818 a rdfs:Class ;
  rdfs:label "Abnormality of the endocrine system" ;
  rdfs:comment "An abnormality of the endocrine system." ;
  rdfs:subClassOf obo:HP_0000118 .

obo:UBERON_0000052 a rdfs:Class ;
  rdfs:label "fornix of brain" ;
  rdfs:comment "A C-shaped bundle of fibres (axons) in the brain, and carries signals from the hippocampus to the mammillary bodies and septal nuclei. It is typically divided into the columns (crus), body, commissure and the pre-commissural and post-commissural fornix (MM)." ;
  rdfs:subClassOf obo:UBERON_0007702 .

obo:ERO_0001236 a rdfs:Class ;
  rdfs:label "magnetic resonance spectroscopy" ;
  rdfs:comment "A physiological assay that complements magnetic resonance imaging (MRI) as a non-invasive means for the characterization of tissue. While MRI uses the signal from hydrogen protons to form anatomic images, proton MRS uses this information to determine the concentration of brain metabolites such as N-acetyl aspartate (NAA), choline (Cho), creatine (Cr) and lactate in the tissue examined." ;
  rdfs:subClassOf obo:ERO_0001292 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#childhood_epilepsy_with_occipital_paroxysm> a rdfs:Class ;
  rdfs:label "childhood epilepsy with occipital paroxysm" ;
  rdfs:seeAlso <http://www.case.edu/EpSO.owl#ChildhoodEpilepsyWithOccipitalParoxysms> ;
  rdfs:subClassOf <https://bio.scai.fraunhofer.de/ontology/epilepsy#simple_focal_seizure> .

obo:BFO_0000035 a rdfs:Class ;
  rdfs:label "process boundary" ;
  rdfs:comment "p is a process boundary =Def. p is a temporal part of a process & p has no proper temporal parts. (axiom label in BFO2 Reference: [084-001])" ;
  rdfs:subClassOf obo:BFO_0000003 .

<https://bio.scai.fraunhofer.de/ontology/0000402> a rdfs:Class ;
  rdfs:label "diagnosis TM_BIN" ;
  rdfs:comment "The 'diagnosis TM_BIN' concept enables a compilation of diverse concepts that are related to diagnosis in Epilepsy via the Axiome 'isDiagnosisFor some epilepsy'.  Thus enables the adaptation of the ontology for text mining purposes for Epilepsy related information retrieval and information extraction." .

obo:HP_0011446 a rdfs:Class ;
  rdfs:label "Abnormality of higher mental function" ;
  rdfs:comment "Cognitive, psychiatric or memory anomaly." ;
  rdfs:subClassOf obo:HP_0012638 .

obo:DOID_4248 a rdfs:Class ;
  rdfs:label "coronary stenosis" ;
  rdfs:subClassOf obo:DOID_3393 .

obo:UBERON_0002702 a rdfs:Class ;
  rdfs:label "middle frontal gyrus" ;
  rdfs:comment "Component of the frontal lobe, lateral aspect (Christine Fennema-Notestine)." ;
  rdfs:subClassOf obo:UBERON_0015593 .

obo:HP_0012372 a rdfs:Class ;
  rdfs:label "Abnormal eye morphology" ;
  rdfs:comment "A structural anomaly of the globe of the eye, or bulbus oculi." ;
  rdfs:subClassOf obo:HP_0000478 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#unknown_onset_seizure> a rdfs:Class ;
  rdfs:label "unknown onset seizure" ;
  rdfs:subClassOf <https://bio.scai.fraunhofer.de/ontology/epilepsy#seizure_classification> .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#orbitofrontal_cortex_seizure> a rdfs:Class ;
  rdfs:label "orbitofrontal cortex seizure" ;
  rdfs:subClassOf <https://bio.scai.fraunhofer.de/ontology/epilepsy#frontal_lobe_seizure> .

obo:MF_0000008 a rdfs:Class ;
  rdfs:label "cognitive process" ;
  rdfs:comment "A mental process that creates, modifies or has as participant some cognitive representation." ;
  rdfs:subClassOf obo:MF_0000020 .

obo:OGMS_0000096 a rdfs:Class ;
  rdfs:label "health care process" ;
  rdfs:comment "A planned process with the objective to improve the health status of a patient that directly involves the treatment, diagnosis, or prevention of disease or injury of a patient" ;
  rdfs:subClassOf obo:OBI_0000011 .

obo:SYMP_0000734 a rdfs:Class ;
  rdfs:label "stroke" ;
  rdfs:comment "Stroke is a nervous system symptom characterized by a sudden diminution or loss of consciousness, sensation, and voluntary motion caused by rupture or obstruction (as by a clot) of a blood vessel of the brain." ;
  rdfs:subClassOf <https://bio.scai.fraunhofer.de/ontology/epilepsy#hypoxic-ischemic> .

obo:SYMP_0019177 a rdfs:Class ;
  rdfs:label "fatigue" ;
  rdfs:comment "Fatigue is a neurological and physiological symptom characterized by a weariness or exhaustion from labor, exertion, or stress." ;
  rdfs:subClassOf obo:SYMP_0000410 .

obo:HP_0032048 a rdfs:Class ;
  rdfs:label "Focal cortical dysplasia type Ia" ;
  rdfs:comment "A subtype of focal cortical dysplasia type I that is characterized by abnormal radial cortical lamination." ;
  rdfs:seeAlso <http://www.case.edu/EpSO.owl#FocalCorticalDysplasiaTypeIA> ;
  rdfs:subClassOf obo:HP_0032047 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#paroxysmal_exercise_induced_dyskinesia> a rdfs:Class ;
  rdfs:label "paroxysmal exercise induced dyskinesia" ;
  rdfs:subClassOf obo:MONDO_0017657 .

obo:RS_0004315 a rdfs:Class ;
  rdfs:label "SD-GEPR-9" ;
  rdfs:subClassOf obo:RS_0000765 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#early-onset_benign_childhood_occipital_seizure> a rdfs:Class ;
  rdfs:label "early-onset benign childhood occipital seizure" ;
  rdfs:subClassOf obo:SYMP_0000124 .

obo:UBERON_0016525 a rdfs:Class ;
  rdfs:label "frontal lobe" ;
  rdfs:comment "Frontal lobe is the anterior-most of five lobes of the cerebral hemisphere. It is bounded by the central sulcus on its posterior border and by the longitudinal cerebral fissure on its medial border." ;
  rdfs:seeAlso <http://www.case.edu/EpSO.owl#FrontalLobe> ;
  rdfs:subClassOf obo:UBERON_0016526 .

obo:DOID_10907 a rdfs:Class ;
  rdfs:label "microcephaly" ;
  rdfs:comment "OMIM mapping confirmed by DO. [SN]." ;
  rdfs:seeAlso <http://www.case.edu/EpSO.owl#Microcephaly> ;
  rdfs:subClassOf obo:DOID_936 .

obo:HP_0012415 a rdfs:Class ;
  rdfs:label "Abnormal blood gas level" ;
  rdfs:comment "An abnormality of the partial pressure of oxygen or carbon dioxide in the arterial blood." ;
  rdfs:subClassOf obo:HP_0002795 .

obo:UBERON_0001891 a rdfs:Class ;
  rdfs:label "midbrain" ;
  rdfs:comment "The midbrain is the middle division of the three primary divisions of the developing chordate brain or the corresponding part of the adult brain (in vertebrates, includes a ventral part containing the cerebral peduncles and a dorsal tectum containing the corpora quadrigemina and that surrounds the aqueduct of Sylvius connecting the third and fourth ventricles)[GO]." ;
  rdfs:subClassOf obo:UBERON_0002616 .

obo:NCIT_C103849 a rdfs:Class ;
  rdfs:label "Pittsburgh Sleep Quality Index" ;
  rdfs:comment "A self-rated questionnaire which assesses sleep quality and disturbances over a one month time interval." ;
  rdfs:subClassOf obo:NCIT_C20993 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#metabolic_etiology> a rdfs:Class ;
  rdfs:label "metabolic etiology" ;
  rdfs:seeAlso <http://www.case.edu/EpSO.owl#MetabolicCause> , <https://www.epilepsydiagnosis.org/aetiology/metabolic-groupoverview.html> ;
  rdfs:subClassOf obo:NCIT_C16390 .

obo:HP_0004372 a rdfs:Class ;
  rdfs:label "Reduced consciousness/confusion" ;
  rdfs:subClassOf obo:HP_0011446 .

obo:DOID_2316 a rdfs:Class ;
  rdfs:label "brain ischemia" ;
  rdfs:comment "An ischemia that is characterized by insufficient blood flow to the brain to meet metabolic demand." ;
  rdfs:subClassOf obo:DOID_326 , obo:DOID_6713 .

obo:NBO_0000019 a rdfs:Class ;
  rdfs:label "licking" ;
  rdfs:comment "The act of stroking or touching with the tongue [NBO:AC]" ;
  rdfs:seeAlso <https://www.aboutkidshealth.ca/article?contentid=2060&language=english> ;
  rdfs:subClassOf obo:NBO_0000748 .

obo:NCIT_C50726 a rdfs:Class ;
  rdfs:label "Regurgitation" ;
  rdfs:comment "Flow in the opposite direction from normal, as the casting up of undigested food or gas from the stomach, or the backward flowing of blood into the heart, or between the chambers of the heart when a valve is incompetent." ;
  rdfs:subClassOf obo:SYMP_0000459 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#speech_arrest> a rdfs:Class ;
  rdfs:label "speech arrest" ;
  rdfs:subClassOf obo:SYMP_0000387 .

obo:PATO_0000140 a rdfs:Class ;
  rdfs:label "position" ;
  rdfs:comment "A spatial quality inhering in a bearer by virtue of the bearer's spatial location relative to other objects in the vicinity." ;
  rdfs:subClassOf obo:PATO_0001018 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#sleep_spindle> a rdfs:Class ;
  rdfs:label "sleep spindle" ;
  rdfs:seeAlso <https://emedicine.medscape.com/article/1139332-overview#a1> ;
  rdfs:subClassOf <https://bio.scai.fraunhofer.de/ontology/epilepsy#normal_EEG_pattern> .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#flickering_light> a rdfs:Class ;
  rdfs:label "flickering light" ;
  rdfs:seeAlso <https://www.epilepsysociety.org.uk/photosensitive-epilepsy#.Xmob-fkzbIU> ;
  rdfs:subClassOf <https://bio.scai.fraunhofer.de/ontology/epilepsy#positive_visual_hallucination> .

obo:NCIT_C81328 a rdfs:Class ;
  rdfs:label "Body Weight" ;
  rdfs:comment "The weight of a subject." ;
  rdfs:subClassOf obo:NCIT_C19332 .

obo:UBERON_0013541 a rdfs:Class ;
  rdfs:label "Brodmann (1909) area 10" ;
  rdfs:comment "Brodmann area 10, or BA10, is part of the frontal cortex in the human brain. BA10 encompasses the most anterior part of the frontal cortex, known as the frontopolar region. This area is believed to play a part in strategic processes involved in memory retrieval and executive function. This area is also called frontopolar area 10, and it refers to a subdivision of the cytoarchitecturally defined frontal region of cerebral cortex. It occupies the most rostral portions of the superior frontal gyrus and the middle frontal gyrus. In humans, on the medial aspect of the hemisphere it is bounded ventrally by the superior rostral sulcus (H). It does not extend as far as the cingulate sulcus. Cytoarchitecturally it is bounded dorsally by the granular frontal area 9, caudally by the middle frontal area 46, and ventrally by the orbital area 47 and by the rostral area 12 or, in an early version of Brodmann's cortical map (Brodmann-1909), the prefrontal Brodmann area 11-1909." ;
  rdfs:subClassOf obo:UBERON_0013529 .

obo:HP_0500173 a rdfs:Class ;
  rdfs:label "Reflex asystolic syncope" ;
  rdfs:comment "A loss of consciousness followed by stiffening and brief clonic movements affecting some or all limbs, often misinterpreted as an epileptic seizure." ;
  rdfs:subClassOf obo:HP_0001279 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#limbic_epilepsy> a rdfs:Class ;
  rdfs:label "limbic epilepsy" ;
  rdfs:subClassOf <https://bio.scai.fraunhofer.de/ontology/epilepsy#symptomatic_epilepsy> .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#normal_EEG_pattern> a rdfs:Class ;
  rdfs:label "normal EEG pattern" ;
  rdfs:seeAlso <http://www.case.edu/EpSO.owl#NormalEEGPattern> ;
  rdfs:subClassOf obo:OBI_0002186 .

obo:HP_0006813 a rdfs:Class ;
  rdfs:label "Hemiclonic seizures" ;
  rdfs:subClassOf obo:HP_0002266 .

obo:MONDO_0100020 a rdfs:Class ;
  rdfs:label "atypical childhood epilepsy with centrotemporal spikes" ;
  rdfs:comment "A childhood-onset epilepsy that is characterized by frequent seizures of multiple types, including nocturnal focal motor and fronto-parietal opercular seizures, and daytime focal motor seizures with negative myoclonus and atypical absence seizures. Centrotemporal sharp waves are seen on EEG. During the phase of the epilepsy when seizures are frequent, neuropsychological deficits and motor impairment may be present. These deficits improve when seizures remit." ;
  rdfs:subClassOf obo:MONDO_0020072 .

obo:SYMP_0000571 a rdfs:Class ;
  rdfs:label "insomnia" ;
  rdfs:comment "Insomnia is a sleep disturbance characterized by prolonged and usually abnormal inability to obtain adequate sleep." ;
  rdfs:seeAlso <https://www.epilepsysociety.org.uk/7-top-tips-better-sleep-epilepsy-and-insomnia> , <http://www.case.edu/EpSO.owl#Insomnia> ;
  rdfs:subClassOf obo:SYMP_0000566 .

obo:HP_0032667 a rdfs:Class ;
  rdfs:label "Myoclonic status epilepticus" ;
  rdfs:comment "A type of motor status epilepticus with repeating bilateral sudden brief (less than 100 ms) involuntary single or multiple contraction of muscles or muscle groups of variable topography." ;
  rdfs:subClassOf obo:HP_0032658 .

obo:UBERON_0002316 a rdfs:Class ;
  rdfs:label "white matter" ;
  rdfs:comment "Neural tissue consisting of myelinated axons connecting grey matter areas of the central nervous system." ;
  rdfs:subClassOf obo:UBERON_0011215 .

obo:CMO_0000027 a rdfs:Class ;
  rdfs:label "white blood cell count" ;
  rdfs:seeAlso <https://www.webmd.com/epilepsy/guide/epilepsy-blood-test> ;
  rdfs:subClassOf obo:CMO_0002341 .

obo:HP_0000234 a rdfs:Class ;
  rdfs:label "Abnormality of the head" ;
  rdfs:comment "An abnormality of the head." ;
  rdfs:subClassOf obo:HP_0000152 .

obo:DOID_2914 a rdfs:Class ;
  rdfs:label "immune system disease" ;
  rdfs:comment "A disease of anatomical entity that is located_in the immune system." ;
  rdfs:subClassOf obo:DOID_7 .

obo:HP_0010853 a rdfs:Class ;
  rdfs:label "EEG with periodic lateralized epileptiform discharges" ;
  rdfs:comment "Periodic lateralized epileptiform discharges (PLEDs)are periodic, lateralized, and epileptiform. PLEDs show a relatively constant interval between discharges (0.5 to 3 seconds)." ;
  rdfs:seeAlso <http://www.case.edu/EpSO.owl#PeriodicLateralizedEpileptiformDischarge> ;
  rdfs:subClassOf obo:HP_0011186 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#multilobar_resection> a rdfs:Class ;
  rdfs:label "multilobar resection" ;
  rdfs:seeAlso <https://pdfs.semanticscholar.org/1758/8f2f2affb26e5ac437702e13af64499fd522.pdf> ;
  rdfs:subClassOf obo:OMIABIS_0001041 .

obo:HP_0010929 a rdfs:Class ;
  rdfs:label "Abnormal blood cation concentration" ;
  rdfs:comment "An abnormality of cation homeostasis." ;
  rdfs:subClassOf obo:HP_0003111 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#genital_automatism> a rdfs:Class ;
  rdfs:label "genital automatism" ;
  rdfs:subClassOf obo:NBO_0000705 .

obo:NCIT_C117014 a rdfs:Class ;
  rdfs:label "Cyclical Vomiting" ;
  rdfs:comment "A condition characterized by recurrent, self-limiting episodes of vomiting associated with intense nausea, pallor, and lethargy. It is commonly a migraine precursor." ;
  rdfs:subClassOf <https://bio.scai.fraunhofer.de/ontology/epilepsy#migraine_associated_disorder> .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#vertical_occular_oscillation> a rdfs:Class ;
  rdfs:label "vertical occular oscillation" ;
  rdfs:subClassOf <https://bio.scai.fraunhofer.de/ontology/epilepsy#occular_oscillation> .

obo:SYMP_0000290 a rdfs:Class ;
  rdfs:label "belching" ;
  rdfs:comment "Belching is a digestive system symptom involving the sudden expulsion of gas from the stomach through the mouth." ;
  rdfs:subClassOf obo:SYMP_0000459 .

obo:HP_0002664 a rdfs:Class ;
  rdfs:label "Neoplasm" ;
  rdfs:comment "An organ or organ-system abnormality that consists of uncontrolled autonomous cell-proliferation which can occur in any part of the body as a benign or malignant neoplasm (tumour)." ;
  rdfs:subClassOf <https://bio.scai.fraunhofer.de/ontology/epilepsy#structural_etiology> .

obo:HP_0032052 a rdfs:Class ;
  rdfs:label "Focal cortical dysplasia type IIa" ;
  rdfs:comment "A subtype of focal cortical dysplasia type II that is characterized by dysmorphic neurons, which present with a significantly enlarged cell body and nucleus, malorientation, abnormally distributed intracellular Nissl substance and cytoplasmic accumulation of neurofilament proteins." ;
  rdfs:seeAlso <http://www.case.edu/EpSO.owl#FocalCorticalDysplasiaTypeIIA> ;
  rdfs:subClassOf obo:HP_0032051 .

obo:UBERON_0006477 a rdfs:Class ;
  rdfs:label "Brodmann (1909) area 34" ;
  rdfs:comment "Brodmann area 34 is a part of the brain. It has been described as part of the entorhinal area. It has been described as part of the superior temporal gyrus." ;
  rdfs:subClassOf obo:UBERON_0013529 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#focal_cognitive_seizure_with_illusion> a rdfs:Class ;
  rdfs:label "focal cognitive seizure with illusion" ;
  rdfs:subClassOf <https://bio.scai.fraunhofer.de/ontology/epilepsy#focal_cognitive_seizure> .

obo:UBERON_0006472 a rdfs:Class ;
  rdfs:label "Brodmann (1909) area 6" ;
  rdfs:comment "Brodmann area 6, or BA6, is part of the frontal cortex in the human brain. Situated just anterior to the primary motor cortex, it is composed of the premotor cortex and, medially, the supplementary motor area, or SMA. This large area of the frontal cortex is believed to play a role in the planning of complex, coordinated movements. Brodmann area 6 is also called agranular frontal area 6 in humans because it lacks an internal granular cortical layer (layer IV). It is a subdivision of the cytoarchitecturally defined precentral region of cerebral cortex. In the human brain, it is located on the portions of the precentral gyrus that are not occupied by the gigantopyramidal area 4; furthermore, BA6 extends onto the caudal portions of the superior frontal and middle frontal gyri. It extends from the cingulate sulcus on the medial aspect of the hemisphere to the lateral sulcus on the lateral aspect. It is bounded rostrally by the granular frontal region and caudally by the gigantopyramidal area 4 (Brodmann, 1909)." ;
  rdfs:subClassOf obo:UBERON_0013529 .

obo:NCBITaxon_9989 a rdfs:Class ;
  rdfs:label "Rodentia" ;
  rdfs:subClassOf obo:NCBITaxon_40674 .

obo:DOID_0060281 a rdfs:Class ;
  rdfs:label "photosensitive epilepsy" ;
  rdfs:comment "An epilepsy characterized by seizures triggered by visual stimuli that form patterns in space or time, such as flashing lights." ;
  rdfs:seeAlso <https://www.epilepsysociety.org.uk/photosensitive-epilepsy#.Xl9_lqgzbIV> ;
  rdfs:subClassOf obo:DOID_1826 .

obo:DOID_870 a rdfs:Class ;
  rdfs:label "neuropathy" ;
  rdfs:comment "A nervous system disease that is located_in nerves or nerve cells." ;
  rdfs:subClassOf obo:DOID_574 .

obo:DOID_308 a rdfs:Class ;
  rdfs:label "early myoclonic encephalopathy" ;
  rdfs:subClassOf obo:MONDO_0100022 .

obo:DOID_3620 a rdfs:Class ;
  rdfs:label "central nervous system cancer" ;
  rdfs:comment "A nervous system cancer that is located_in the central nervous system." ;
  rdfs:subClassOf obo:DOID_331 .

obo:UBERON_0006483 a rdfs:Class ;
  rdfs:label "Brodmann (1909) area 46" ;
  rdfs:comment "Brodmann area 46, or BA46, is part of the frontal cortex in the human brain. It is between BA10 and BA45. BA46 is known as middle frontal area 46. In the human it occupies approximately the middle third of the middle frontal gyrus and the most rostral portion of the inferior frontal gyrus. Brodmann area 46 roughly corresponds with the dorsolateral prefrontal cortex (DLPFC), although the borders of area 46 are based on cytoarchitecture rather than function. The DLPFC also encompasses part of granular frontal area 9, directly adjacent on the dorsal surface of the cortex. Cytoarchitecturally, BA46 is bounded dorsally by the granular frontal area 9, rostroventrally by the frontopolar area 10 and caudally by the triangular area 45 (Brodmann-1909). There is some discrepancy between the extent of BA8 (Brodmann-1905) and the same area as described by Walker (1940)" ;
  rdfs:subClassOf obo:UBERON_0013529 .

obo:MONDO_0005384 a rdfs:Class ;
  rdfs:label "partial epilepsy" ;
  rdfs:comment "A seizure caused by a localized disorder." ;
  rdfs:subClassOf obo:DOID_1826 .

obo:OMIT_0008783 a rdfs:Class ;
  rdfs:label "Kidney Function Tests" ;
  rdfs:subClassOf obo:OBI_0000070 .

obo:UBERON_0006101 a rdfs:Class ;
  rdfs:label "Brodmann (1909) area 24" ;
  rdfs:comment "." ;
  rdfs:subClassOf obo:UBERON_0013529 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#right_hemispheric_stroke> a rdfs:Class ;
  rdfs:label "right hemispheric stroke" ;
  rdfs:seeAlso <https://mrri.org/right-hemisphere-stroke-center/> , <http://www.case.edu/EpSO.owl#RightHemisphericStroke> ;
  rdfs:subClassOf obo:DOID_936 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#rhythmic_temporal_theta_of_drowsiness> a rdfs:Class ;
  rdfs:label "rhythmic temporal theta of drowsiness" ;
  rdfs:seeAlso <http://www.case.edu/EpSO.owl#RhytmicTemporalThetaBurstsofDrowsiness> ;
  rdfs:subClassOf <https://bio.scai.fraunhofer.de/ontology/epilepsy#rhythmic_benign_variant> .

obo:BFO_0000020 a rdfs:Class ;
  rdfs:label "specifically dependent continuant" ;
  rdfs:comment "A continuant that inheres in or is borne by other entities. Every instance of A requires some specific instance of B which must always be the same." ;
  rdfs:subClassOf obo:BFO_0000002 .

obo:NCIT_C15308 a rdfs:Class ;
  rdfs:label "Psychotherapy" ;
  rdfs:comment "A method of treating disease, esp. psychic disorders, by mental rather than pharmacological means (e.g., suggestion, re-education, hypnotism, and psychoanalysis). (Taber's)" ;
  rdfs:subClassOf obo:OGMS_0000112 .

obo:NBO_0000570 a rdfs:Class ;
  rdfs:label "head bobbing" ;
  rdfs:comment "Movement of the head in the vertical plane. [NBO:GVG]" ;
  rdfs:seeAlso <https://www.epilepsy.com/learn/types-seizures/atonic-seizures> ;
  rdfs:subClassOf obo:NBO_0000020 .

obo:NCIT_C116454 a rdfs:Class ;
  rdfs:label "Functional Connectivity Magnetic Resonance Imaging" ;
  rdfs:comment "A technique that monitors blood oxygen level dependent (BOLD) signals to map distant brain regions that work together while performing a task." ;
  rdfs:subClassOf obo:OMIT_0027689 .

obo:DOID_17 a rdfs:Class ;
  rdfs:label "musculoskeletal system disease" ;
  rdfs:comment "A disease of anatomical entity that occurs in the muscular and/or skeletal system." ;
  rdfs:subClassOf obo:DOID_7 .

obo:DOID_1307 a rdfs:Class ;
  rdfs:label "dementia" ;
  rdfs:comment "A cognitive disorder resulting from a loss of brain function affecting memory, thinking, language, judgement and behavior." ;
  rdfs:subClassOf obo:DOID_1561 .

obo:HP_0011442 a rdfs:Class ;
  rdfs:label "Abnormality of central motor function" ;
  rdfs:comment "An anomaly of the control or production of movement in the central nervous system." ;
  rdfs:subClassOf obo:HP_0012638 .

obo:HP_0011021 a rdfs:Class ;
  rdfs:label "Abnormality of circulating enzyme level" ;
  rdfs:subClassOf obo:HP_0010876 .

obo:UBERON_0006794 a rdfs:Class ;
  rdfs:label "visual processing part of nervous system" ;
  rdfs:comment "This grouping class is primarily to accommodate GO" ;
  rdfs:subClassOf obo:UBERON_0011216 .

obo:DOID_9074 a rdfs:Class ;
  rdfs:label "systemic lupus erythematosus" ;
  rdfs:comment "A lupus erythematosus that is an inflammation of connective tissue marked by skin rashes, joint pain and swelling, inflammation of the kidneys and inflammation of the tissue surrounding the heart." ;
  rdfs:subClassOf obo:DOID_1575 , obo:DOID_8857 .

obo:MONDO_0016688 a rdfs:Class ;
  rdfs:label "fibrillary astrocytoma" ;
  rdfs:comment "The most frequent histological variant of diffuse astrocytoma. It is predominantly composed of fibrillary neoplastic astrocytes. Nuclear atypia is a diagnostic criterion but mitotic activity, necrosis and microvascular proliferation are absent. The occasional or regional occurrence of gemistocytic neoplastic cells is compatible with the diagnosis of fibrillary astrocytoma. (WHO)" ;
  rdfs:seeAlso <https://www.epilepsy.com/learn/professionals/co-existing-disorders/brain-tumors/astrocytoma> ;
  rdfs:subClassOf obo:MONDO_0016686 .

obo:DOID_4194 a rdfs:Class ;
  rdfs:label "glucose metabolism disease" ;
  rdfs:subClassOf obo:DOID_0050013 .

obo:OGMS_0000014 a rdfs:Class ;
  rdfs:label "clinical finding" ;
  rdfs:comment "A representation that is either the output of a clinical history taking or a physical examination or an image finding, or some combination thereof." ;
  rdfs:subClassOf obo:OGMS_0000123 .

obo:HP_0100310 a rdfs:Class ;
  rdfs:label "Epidural hemorrhage" ;
  rdfs:comment "Hemorrhage occurring between the dura mater and the skull." ;
  rdfs:subClassOf obo:HP_0002170 .

obo:NCIT_C113191 a rdfs:Class ;
  rdfs:label "Have Feeling of Fullness or Heaviness in Stomach Area" ;
  rdfs:comment "A question about whether an individual has or had a feeling of fullness or heaviness in the area of the stomach." ;
  rdfs:subClassOf obo:SYMP_0000459 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#simple_focal_seizure> a rdfs:Class ;
  rdfs:label "simple focal seizure" ;
  rdfs:seeAlso <http://www.case.edu/EpSO.owl#SingleFocalEpilepsy> ;
  rdfs:subClassOf obo:DOID_1826 .

obo:UBERON_0004714 a rdfs:Class ;
  rdfs:label "septum pellucidum" ;
  rdfs:comment "A triangular double membrane, consisting of glial cells and fibers (Heimer, 1996) separating the anterior horns of the lateral ventricles of the brain. It is situated in the median plane and bounded by the corpus callosum and the body and columns of the fornix." ;
  rdfs:subClassOf obo:UBERON_0000119 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#hypoxia_model> a rdfs:Class ;
  rdfs:label "hypoxia model" ;
  rdfs:subClassOf <https://bio.scai.fraunhofer.de/ontology/epilepsy#neonatal_hypoxia_model> .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#in_silico_model> a rdfs:Class ;
  rdfs:label "in silico model" ;
  rdfs:subClassOf obo:NCIT_C19272 .

obo:OMIT_0006603 a rdfs:Class ;
  rdfs:label "First Aid" ;
  rdfs:seeAlso <https://www.epilepsy.com/learn/seizure-first-aid-and-safety/adapting-first-aid-plans/seizure-first-aid> ;
  rdfs:subClassOf obo:OGMS_0000112 .

obo:HP_0002921 a rdfs:Class ;
  rdfs:label "Abnormality of the cerebrospinal fluid" ;
  rdfs:comment "An abnormality of the cerebrospinal fluid (CSF)." ;
  rdfs:subClassOf obo:HP_0002011 .

obo:PATO_0002168 a rdfs:Class ;
  rdfs:label "displaced to" ;
  rdfs:comment "An angular placement quality inhering in a bearer by virtue of the bearer being changed in position in relation to another entity." ;
  rdfs:subClassOf obo:PATO_0000133 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#periodic_pattern> a rdfs:Class ;
  rdfs:label "periodic pattern" ;
  rdfs:seeAlso <http://www.case.edu/EpSO.owl#PeriodicPattern> ;
  rdfs:subClassOf <https://bio.scai.fraunhofer.de/ontology/epilepsy#special_pattern> .

obo:NCIT_C124040 a rdfs:Class ;
  rdfs:label "Continuous Positive Airway Pressure" ;
  rdfs:comment "A form of non-invasive mechanical pressure support ventilation that uses a continuous positive airway pressure level to support spontaneous breathing activity." ;
  rdfs:subClassOf obo:OGMS_0000112 .

obo:MONDO_0100034 a rdfs:Class ;
  rdfs:label "cerebral folate deficiency" ;
  rdfs:comment "Cerebral folate deficiency is defined as a neurological syndrome associated with low CSF 5-methyltetrahydrofolate (5MTHF), the active folate metabolite, in the presence of normal folate metabolism outside the nervous system. Cerebral folate deficiency can result from either disturbed folate transport or from increased folate turnover within the central nervous system." ;
  rdfs:subClassOf <https://bio.scai.fraunhofer.de/ontology/epilepsy#metabolic_etiology> .

obo:OBA_0000116 a rdfs:Class ;
  rdfs:label "neurotransmitter levels" ;
  rdfs:comment "The amount of a neurotransmitter." ;
  rdfs:subClassOf obo:CMO_0000000 .

<https://bio.scai.fraunhofer.de/ontology/0000510> a rdfs:Class ;
  rdfs:label "brain functional connectivity measure" ;
  rdfs:subClassOf <https://bio.scai.fraunhofer.de/ontology/0000508> .

obo:MONDO_0015916 a rdfs:Class ;
  rdfs:label "rare neuroinflammatory or neuroimmunological disease" ;
  rdfs:seeAlso <https://github.com/monarch-initiative/mondo/issues/254> ;
  rdfs:subClassOf obo:DOID_863 .

obo:NBO_0000607 a rdfs:Class ;
  rdfs:label "cognitive behavior" ;
  rdfs:comment "\"Behaviour related to cognitive processes.\" [NBO:JH]" ;
  rdfs:subClassOf obo:NBO_0000313 .

obo:ERO_0001292 a rdfs:Class ;
  rdfs:label "physiological assay" ;
  rdfs:comment "An organismal assay designed to capture information pertaining to the the organic processes and phenomena of an organism or any of its parts or of a particular bodily process." ;
  rdfs:subClassOf obo:ERO_0001285 .

obo:OMIT_0002726 a rdfs:Class ;
  rdfs:label "Aversive Therapy" ;
  rdfs:subClassOf obo:NCIT_C15308 .

obo:HP_0012668 a rdfs:Class ;
  rdfs:label "Vasovagal syncope" ;
  rdfs:subClassOf obo:HP_0001279 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#premotor_epilepsy> a rdfs:Class ;
  rdfs:label "premotor epilepsy" ;
  rdfs:seeAlso <http://www.case.edu/EpSO.owl#PremotorEpilepsy> ;
  rdfs:subClassOf <https://bio.scai.fraunhofer.de/ontology/epilepsy#lateral_frontal_epilepsy> .

obo:UBERON_0000481 a rdfs:Class ;
  rdfs:label "multi-tissue structure" ;
  rdfs:comment "Anatomical structure that has as its parts two or more portions of tissue of at least two different types and which through specific morphogenetic processes forms a single distinct structural unit demarcated by bona-fide boundaries from other distinct structural units of different types." ;
  rdfs:subClassOf obo:UBERON_0010000 .

obo:SYMP_0000492 a rdfs:Class ;
  rdfs:label "urinary incontinence" ;
  rdfs:comment "Urinary incontinence is a urinary system symptom characterized by the an inability of the body to control the evacuative functions." ;
  rdfs:subClassOf obo:SYMP_0000486 .

obo:MONDO_0044970 a rdfs:Class ;
  rdfs:label "mitochondrial disease" ;
  rdfs:seeAlso <https://www.epilepsydiagnosis.org/aetiology/metabolic-groupoverview.html#mitochondrial> ;
  rdfs:subClassOf <https://bio.scai.fraunhofer.de/ontology/epilepsy#metabolic_etiology> .

obo:NBO_0000719 a rdfs:Class ;
  rdfs:label "alcohol withdrawal induced seizure" ;
  rdfs:comment "\"A type of seizure induced by termination of alcohol administration.\" [NBO:GVG]" ;
  rdfs:seeAlso <https://www.fairview.org/patient-education/115703EN> ;
  rdfs:subClassOf obo:NBO_0000711 .

obo:DOID_9744 a rdfs:Class ;
  rdfs:label "type 1 diabetes mellitus" ;
  rdfs:comment "A diabetes mellitus that results from the body's failure to produce insulin and has_material_basis_in autoimmune destruction of insulin-producing beta cells of the pancreas." ;
  rdfs:subClassOf obo:DOID_9351 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#diaphragmatic_breathing> a rdfs:Class ;
  rdfs:label "diaphragmatic breathing" ;
  rdfs:subClassOf obo:SYMP_0000514 .

obo:DOID_3312 a rdfs:Class ;
  rdfs:label "bipolar disorder" ;
  rdfs:comment "A mood disorder that involves alternating periods of mania and depression." ;
  rdfs:seeAlso <http://www.case.edu/EpSO.owl#BipolarDisorder> ;
  rdfs:subClassOf obo:DOID_3324 .

obo:DOID_0060155 a rdfs:Class ;
  rdfs:label "visual agnosia" ;
  rdfs:comment "An agnosia that is a loss of the ability to visually recognize objects." ;
  rdfs:seeAlso <http://www.case.edu/EpSO.owl#VisualAgnosia> ;
  rdfs:subClassOf obo:DOID_4090 .

obo:PATO_0001912 a rdfs:Class ;
  rdfs:label "physiological state" ;
  rdfs:comment "A quality of a single process inhering in a bearer by virtue of the state of bearer's mechanical, physical, and biochemical processes." ;
  rdfs:subClassOf obo:PATO_0000161 .

obo:HP_0005294 a rdfs:Class ;
  rdfs:label "Arterial dissection" ;
  rdfs:comment "A separation (dissection) of the layers of an artery." ;
  rdfs:subClassOf obo:HP_0011004 .

obo:UBERON_0022776 a rdfs:Class ;
  rdfs:label "composite part spanning multiple base regional parts of brain" ;
  rdfs:subClassOf obo:UBERON_0034925 .

obo:DOID_3118 a rdfs:Class ;
  rdfs:label "hepatobiliary disease" ;
  rdfs:comment "A gastrointestinal system disease that is located_in the liver and/or biliary tract." ;
  rdfs:subClassOf obo:DOID_77 .

obo:NCBITaxon_2759 a rdfs:Class ;
  rdfs:label "Eukaryota" ;
  rdfs:subClassOf obo:NCBITaxon_131567 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#convulsant_drug_model> a rdfs:Class ;
  rdfs:label "convulsant drug model" ;
  rdfs:subClassOf obo:NCIT_C19021 .

obo:DOID_10113 a rdfs:Class ;
  rdfs:label "trypanosomiasis" ;
  rdfs:comment "A parasitic protozoa infectious disease that involves infection caused by parasitic protozoan of the genus Trypanosoma in animals and humans." ;
  rdfs:subClassOf obo:DOID_0050117 .

obo:MONDO_0016685 a rdfs:Class ;
  rdfs:label "low-grade astrocytoma" ;
  rdfs:subClassOf obo:MONDO_0021638 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#beta_activity> a rdfs:Class ;
  rdfs:label "beta activity" ;
  rdfs:seeAlso <http://www.case.edu/EpSO.owl#BetaActivity> , <https://emedicine.medscape.com/article/1139332-overview#a1> ;
  rdfs:subClassOf <https://bio.scai.fraunhofer.de/ontology/epilepsy#normal_EEG_pattern> .

obo:MONDO_0100031 a rdfs:Class ;
  rdfs:label "autosomal dominant epilepsy with auditory features" ;
  rdfs:comment "A genetic focal epilepsy, with focal sensory auditory seizures seen in family members. Seizures often comprise such mild symptoms that they are undiagnosed. There are no implications expected for development or learning and seizures are typically infrequent and well controlled." ;
  rdfs:seeAlso <http://www.case.edu/EpSO.owl#AutosomalDominantPartialEpilepsyWithAuditoryFeatures> ;
  rdfs:subClassOf obo:MONDO_0100030 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#pentylenetetrazol_model> a rdfs:Class ;
  rdfs:label "pentylenetetrazol model" ;
  rdfs:subClassOf <https://bio.scai.fraunhofer.de/ontology/epilepsy#convulsant_drug_model> .

obo:GO_0022414 a rdfs:Class ;
  rdfs:label "reproductive process" ;
  rdfs:comment "A biological process that directly contributes to the process of producing new individuals by one or two organisms. The new individuals inherit some proportion of their genetic material from the parent or parents." ;
  rdfs:subClassOf obo:GO_0008150 .

obo:PW_0000180 a rdfs:Class ;
  rdfs:label "mTOR signaling pathway" ;
  rdfs:comment "mTOR signaling pathway regulates cellular processes such as translation, ribosome biogenesis, cell growth and autophagy and is regulated or responds to growth factors, energy metabolites and/or levels of nutrients." ;
  rdfs:subClassOf obo:GO_0007165 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#focal_autonomic_seizure_with_urge_to_urinate/defecate> a rdfs:Class ;
  rdfs:label "focal autonomic seizure with urge to urinate/defecate" ;
  rdfs:seeAlso <https://www.epilepsydiagnosis.org/seizure/autonomic-overview.html> ;
  rdfs:subClassOf obo:HP_0011154 .

obo:DOID_7998 a rdfs:Class ;
  rdfs:label "hyperthyroidism" ;
  rdfs:comment "A thyroid gland disease that involves an over production of thyroid hormone." ;
  rdfs:seeAlso <https://www.epilepsy.com/learn/professionals/co-existing-disorders/metabolic-disorders/hyperthyroidism> ;
  rdfs:subClassOf obo:DOID_50 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#focal_cognitive_seizure_with_de_javu_/_jamais_vu> a rdfs:Class ;
  rdfs:label "focal cognitive seizure with de javu / jamais vu" ;
  rdfs:subClassOf <https://bio.scai.fraunhofer.de/ontology/epilepsy#focal_cognitive_seizure> .

obo:NBO_0000007 a rdfs:Class ;
  rdfs:label "mouth movement" ;
  rdfs:comment "The act of moving any of the tissues and hard structures surrounding the mouth other than teeth, jaws or filter structures [NBO:AC]" ;
  rdfs:subClassOf obo:NBO_0000001 .

obo:MONDO_0024417 a rdfs:Class ;
  rdfs:label "perceptual disorders" ;
  rdfs:comment "Cognitive disorders characterized by an impaired ability to perceive the nature of objects or concepts through use of the sense organs. These include spatial neglect syndromes, where an individual does not attend to visual, auditory, or sensory stimuli presented from one side of the body." ;
  rdfs:subClassOf obo:DOID_863 .

obo:DOID_936 a rdfs:Class ;
  rdfs:label "brain disease" ;
  rdfs:comment "A central nervous system disease that is located_in the brain." ;
  rdfs:subClassOf obo:DOID_331 .

obo:HP_0010930 a rdfs:Class ;
  rdfs:label "Abnormal blood monovalent inorganic cation concentration" ;
  rdfs:comment "An abnormality of monovalent inorganic cation homeostasis." ;
  rdfs:subClassOf obo:HP_0010929 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#V_wave> a rdfs:Class ;
  rdfs:label "V wave" ;
  rdfs:seeAlso <https://emedicine.medscape.com/article/1139332-overview#a1> ;
  rdfs:subClassOf <https://bio.scai.fraunhofer.de/ontology/epilepsy#normal_EEG_pattern> .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#corpus_callosotomy> a rdfs:Class ;
  rdfs:label "corpus callosotomy" ;
  rdfs:subClassOf obo:OMIABIS_0001041 .

obo:NCIT_C19770 a rdfs:Class ;
  rdfs:label "Molecular Analysis" ;
  rdfs:comment "A laboratory procedure that involves the study of tissues, cells, and fluids using DNA/RNA analysis techniques for the identification of characteristics and abnormalities at the molecular level." ;
  rdfs:subClassOf obo:ERO_0000007 .

obo:HP_0012002 a rdfs:Class ;
  rdfs:label "Experiential auras" ;
  rdfs:comment "Affective, mnemonic or composite perceptual auras with subjective qualities similar to those experienced in life but are recognized by the subject as occurring outside of actual context." ;
  rdfs:subClassOf obo:SYMP_0000124 .

obo:DOID_11199 a rdfs:Class ;
  rdfs:label "hypoparathyroidism" ;
  rdfs:comment "A parathyroid gland disease characterized by decreased function of parathyroid glands with underproduction of parathyroid hormone (PTH), leading to abnormally low ionized calcium levels in the blood." ;
  rdfs:seeAlso <https://www.epilepsy.com/learn/professionals/co-existing-disorders/metabolic-disorders/hypoparathyroidism> ;
  rdfs:subClassOf obo:DOID_11201 .

obo:MONDO_0020071 a rdfs:Class ;
  rdfs:label "infantile epilepsy syndrome" ;
  rdfs:comment "A epilepsy syndrome that occurs between 28 days to one year of life.." ;
  rdfs:subClassOf obo:DOID_225 .

obo:DOID_7 a rdfs:Class ;
  rdfs:label "disease of anatomical entity" ;
  rdfs:comment "A disease that manifests in a defined anatomical structure." ;
  rdfs:subClassOf obo:DOID_4 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#video_telemetry> a rdfs:Class ;
  rdfs:label "video telemetry" ;
  rdfs:seeAlso <https://www.epilepsysociety.org.uk/eeg-electroencephalogram#.XFE6tFwzbIU> ;
  rdfs:subClassOf obo:OBI_0002186 .

obo:DOID_4851 a rdfs:Class ;
  rdfs:label "pilocytic astrocytoma" ;
  rdfs:comment "An astrocytoma that is characterized by cells that look like fibers when viewed under a microscope and is located_in the brain." ;
  rdfs:seeAlso <http://www.case.edu/EpSO.owl#PilocyticAstrocytoma> ;
  rdfs:subClassOf obo:MONDO_0015917 .

obo:PW_0000204 a rdfs:Class ;
  rdfs:label "Notch signaling pathway" ;
  rdfs:comment "Notch signaling pathway regulates processes involved in early embryonic development. It plays an important role in cell fate determination. Target genes of Notch have been implicated in angiogenesis, somitogenesis, gliogenesis. Deregulation of the Notch signaling pathway underlies a broad spectrum of diseases and clinical conditions." ;
  rdfs:subClassOf obo:GO_0007165 .

obo:HP_0002384 a rdfs:Class ;
  rdfs:label "Focal impaired awareness seizure" ;
  rdfs:comment "A type of focal-onset saeizure characterized by impaired awareness. Awareness during a seizure is defined as the patient being fully aware of themself and their environment throughout the seizure, even if immobile. If awareness is impaired at any point during the seizure, the seizure is a focal impaired awareness seizure. The degree of loss of awareness may vary." ;
  rdfs:seeAlso <http://www.case.edu/EpSO.owl#DialepticSeizure> ;
  rdfs:subClassOf <https://bio.scai.fraunhofer.de/ontology/epilepsy#focal_seizure_classification_by_onset_feature> .

obo:MONDO_0000188 a rdfs:Class ;
  rdfs:label "GLUT1 deficiency syndrome" ;
  rdfs:comment "Editor note: todo http://identifiers.org/hgnc/11005" ;
  rdfs:subClassOf <https://bio.scai.fraunhofer.de/ontology/epilepsy#metabolic_etiology> .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#trigeminal_nerve_stimulation> a rdfs:Class ;
  rdfs:label "trigeminal nerve stimulation" ;
  rdfs:subClassOf obo:OGMS_0000112 .

obo:HP_0025267 a rdfs:Class ;
  rdfs:label "Snoring" ;
  rdfs:comment "Deep, noisy breathing during sleep accompanied by hoarse or harsh sounds caused by the vibration of respiratory structures (especially the soft palate) resulting in sound due to obstructed air movement during breathing while sleeping." ;
  rdfs:seeAlso <http://www.case.edu/EpSO.owl#Snoring> ;
  rdfs:subClassOf obo:SYMP_0000566 .

obo:CMO_0001243 a rdfs:Class ;
  rdfs:label "cerebrospinal fluid chloride level" ;
  rdfs:seeAlso <https://link.springer.com/article/10.1007/BF02075764> ;
  rdfs:subClassOf obo:CMO_0001242 .

obo:CMO_0000508 a rdfs:Class ;
  rdfs:label "hemoglobin measurement" ;
  rdfs:seeAlso <https://www.webmd.com/epilepsy/guide/epilepsy-blood-test> ;
  rdfs:subClassOf obo:CMO_0000036 .

obo:CMO_0000038 a rdfs:Class ;
  rdfs:label "mean corpuscular volume" ;
  rdfs:seeAlso <https://www.webmd.com/epilepsy/guide/epilepsy-blood-test> ;
  rdfs:subClassOf obo:CMO_0001356 .

<https://bio.scai.fraunhofer.de/ontology/0000407> a rdfs:Class ;
  rdfs:label "epilepsy syndrome TM_BIN" ;
  rdfs:comment "The 'epilepsy syndrome TM_BIN' concept enables a compilation of diverse concepts that are related to syndromes in Epilepsy via the Axiome 'isSyndromeFor some epilepsy'.  Thus enables the adaptation of the ontology for text mining purposes for Epilepsy related information retrieval and information extraction." .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#post_stroke_seizure> a rdfs:Class ;
  rdfs:label "post stroke seizure" ;
  rdfs:subClassOf <https://bio.scai.fraunhofer.de/ontology/epilepsy#immediate_and_early_post_cerebral_insult_seizure> .

obo:NBO_0000738 a rdfs:Class ;
  rdfs:label "gelastic epilepsy" ;
  rdfs:comment "\"A type of epilepsy that is characterised a sudden burst of energy, usually in the form of laughing.\" [NBO:GVG]" ;
  rdfs:subClassOf obo:DOID_1826 .

obo:MFOMD_0000119 a rdfs:Class ;
  rdfs:label "dissociation" ;
  rdfs:comment """
A disruption in the usually integrated functions of consciousness, memory, identity, or perception of the environment. 
The disturbance may be sudden or gradual, transient or chronic.


DSM-IV-TR (american Psychiatric Association)""" ;
  rdfs:subClassOf obo:MFOMD_0000024 .

obo:UBERON_0005913 a rdfs:Class ;
  rdfs:label "zone of bone organ" ;
  rdfs:subClassOf obo:UBERON_0034944 .

obo:DOID_319 a rdfs:Class ;
  rdfs:label "spinal cord disease" ;
  rdfs:subClassOf obo:DOID_331 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#World_Health_Organization_quality_of_life_instrument,_short_form> a rdfs:Class ;
  rdfs:label "World Health Organization quality of life instrument, short form" ;
  rdfs:subClassOf obo:NCIT_C20993 .

obo:UBERON_0022303 a rdfs:Class ;
  rdfs:label "nervous system cell part layer" ;
  rdfs:comment "Single layer of a laminar structure, identified by different density, arrangement or size of cells and processes arranged in flattened layers or lamina[CUMBO]." ;
  rdfs:subClassOf obo:UBERON_0005162 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#hypoxic-ischemic> a rdfs:Class ;
  rdfs:label "hypoxic-ischemic" ;
  rdfs:subClassOf <https://bio.scai.fraunhofer.de/ontology/epilepsy#structural_etiology> .

obo:NBO_0000611 a rdfs:Class ;
  rdfs:label "olfactory hallucination" ;
  rdfs:comment "\"A form of hallucination that involves perceiving odors without odor stimulus.\" [NBO:GVG]" ;
  rdfs:seeAlso <http://www.tasteandsmell.com/june2013.htm> ;
  rdfs:subClassOf obo:NBO_0000308 .

obo:NBO_0000678 a rdfs:Class ;
  rdfs:label "febrile seizure" ;
  rdfs:comment "\"A type of seizure associated with a significant rise in body temperature.\" [wikpedia:http\\://en.wikipedia.org/wiki/Febrile_seizure]" ;
  rdfs:seeAlso <https://www.mayoclinic.org/diseases-conditions/febrile-seizure/symptoms-causes/syc-20372522> , <https://www.epilepsy.com/learn/about-epilepsy-basics/what-are-risk-factors> ;
  rdfs:subClassOf obo:NBO_0000686 .

obo:MP_0001845 a rdfs:Class ;
  rdfs:label "abnormal inflammatory response" ;
  rdfs:comment "aberrant reaction of the microcirculation characterized by movement of fluid and leukocytes from the blood into extravascular tissues" ;
  rdfs:subClassOf obo:HP_0010978 .

obo:UBERON_0013538 a rdfs:Class ;
  rdfs:label "Brodmann (1909) area 7" ;
  rdfs:comment "Brodmann area 7 is one of Brodmann's cytologically defined regions of the brain. It is involved in locating objects in space. It serves as a point of convergence between vision and proprioception to determine where objects are in relation to parts of the body." ;
  rdfs:subClassOf obo:UBERON_0013529 .

obo:HP_0100755 a rdfs:Class ;
  rdfs:label "Abnormality of salivation" ;
  rdfs:subClassOf obo:HP_0031815 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#biotinidase_and_holocarboxylase_synthase_deficiency> a rdfs:Class ;
  rdfs:label "biotinidase and holocarboxylase synthase deficiency" ;
  rdfs:subClassOf <https://bio.scai.fraunhofer.de/ontology/epilepsy#metabolic_etiology> .

obo:UBERON_0000125 a rdfs:Class ;
  rdfs:label "neural nucleus" ;
  rdfs:comment "A spatially aggregated collection of nerve cell bodies in the CNS, consisting of one or more subpopulations that share cell type, chemical phenotype, and connections, and including nearby cells that share the same cell type, chemical phenotype, and connections. (CUMBO)" ;
  rdfs:subClassOf obo:UBERON_0011215 .

obo:NCIT_C19272 a rdfs:Class ;
  rdfs:label "Transgenic Model" ;
  rdfs:comment "A disease in a transgenic animal with pathologic mechanisms sufficiently similar to those of a human disease for the animal disease to serve as a model." ;
  rdfs:subClassOf obo:NCIT_C71164 .

obo:UBERON_0006088 a rdfs:Class ;
  rdfs:label "inferior parietal cortex" ;
  rdfs:comment "Component of the parietal lobe. The inferior parietal cortex label includes the inferior parietal gyrus and the angular gyrus and lies inferior to the superior parietal gyrus. The rostral and caudal boundaries were the supramarginal gyrus and the parieto-occipital incisure respectively. The medial and lateral boundaries were the superior parietal gyrus and the middle temporal gyrus respectively (Christine Fennema-Notestine)." ;
  rdfs:subClassOf obo:UBERON_0000064 .

obo:HP_0011458 a rdfs:Class ;
  rdfs:label "Abdominal symptom" ;
  rdfs:subClassOf obo:HP_0025032 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#trigger_factor_for_seizure> a rdfs:Class ;
  rdfs:label "trigger factor for seizure" ;
  rdfs:seeAlso <https://www.epilepsy.com/learn/about-epilepsy-basics/what-are-risk-factors> ;
  rdfs:subClassOf obo:NCIT_C17103 .

obo:HP_0002901 a rdfs:Class ;
  rdfs:label "Hypocalcemia" ;
  rdfs:comment "An abnormally decreased calcium concentration in the blood." ;
  rdfs:seeAlso <https://www.epilepsy.com/learn/professionals/co-existing-disorders/metabolic-disorders/electrolyte-abnormalities/hypocalcemia> ;
  rdfs:subClassOf obo:HP_0004363 .

obo:NCIT_C86974 a rdfs:Class ;
  rdfs:label "Wechsler Preschool and Primary Scale of Intelligence" ;
  rdfs:comment "An intelligence test published by Harcourt Assessment and designed for children ages 2 years 6 months to 7 years 3 months. It provides subtest and composite scores that represent intellectual functioning in verbal and performance cognitive domains, and provides a composite score that represents a child's general intellectual ability." ;
  rdfs:subClassOf obo:NCIT_C20993 .

obo:NBO_0000473 a rdfs:Class ;
  rdfs:label "rhythmic behavior phenotype" ;
  rdfs:subClassOf obo:NBO_0000243 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#pharmacoresistant_epilepsy_model> a rdfs:Class ;
  rdfs:label "pharmacoresistant epilepsy model" ;
  rdfs:subClassOf obo:NCIT_C19021 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#generalized_motor_onset_seizure> a rdfs:Class ;
  rdfs:label "generalized motor onset seizure" ;
  rdfs:seeAlso <https://www.epilepsydiagnosis.org/seizure/generalized-seizure-groupoverview.html> ;
  rdfs:subClassOf obo:HP_0002197 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#focal_cognitive_seizure_with_expressive_dysphasia/aphasia> a rdfs:Class ;
  rdfs:label "focal cognitive seizure with expressive dysphasia/aphasia" ;
  rdfs:seeAlso <https://emedicine.medscape.com/article/1176568-clinical> ;
  rdfs:subClassOf <https://bio.scai.fraunhofer.de/ontology/epilepsy#focal_cognitive_seizure> .

obo:MP_0005308 a rdfs:Class ;
  rdfs:label "abnormal circulating ammonia level" ;
  rdfs:comment "aberrant amount of ammonia or its compounds in blood, formed in the body during organic decomposition" ;
  rdfs:subClassOf obo:MP_0009642 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#lateral_occipital_epilepsy> a rdfs:Class ;
  rdfs:label "lateral occipital epilepsy" ;
  rdfs:seeAlso <http://www.case.edu/EpSO.owl#LateralOccipitalEpilepsy> ;
  rdfs:subClassOf <https://bio.scai.fraunhofer.de/ontology/epilepsy#occipital_lobe_epilepsy> .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#late-onset_benign_occipital_seizure> a rdfs:Class ;
  rdfs:label "late-onset benign occipital seizure" ;
  rdfs:subClassOf obo:SYMP_0000124 .

obo:MONDO_0007365 a rdfs:Class ;
  rdfs:label "seizures, benign familial neonatal, 1" ;
  rdfs:comment "Any benign neonatal seizures in which the cause of the disease is a mutation in the KCNQ2 gene." ;
  rdfs:subClassOf obo:MONDO_0016027 .

obo:HP_0025615 a rdfs:Class ;
  rdfs:label "Abscess" ;
  rdfs:subClassOf obo:HP_0032251 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#electrode_implantation> a rdfs:Class ;
  rdfs:label "electrode implantation" ;
  rdfs:subClassOf obo:OMIABIS_0001041 .

obo:MP_0001993 a rdfs:Class ;
  rdfs:label "abnormal blinking" ;
  rdfs:comment "anomaly in the normal reflex of closing the eyes frequently and rapidly" ;
  rdfs:seeAlso <https://www.epilepsysociety.org.uk/absence-seizures#.XEhRulwzbIU> ;
  rdfs:subClassOf obo:MP_0004924 .

obo:DOID_225 a rdfs:Class ;
  rdfs:label "syndrome" ;
  rdfs:comment "A disease characterized by a group of signs and symptoms that occur together and characterize a particular abnormality." ;
  rdfs:subClassOf obo:DOID_4 .

obo:CMO_0000670 a rdfs:Class ;
  rdfs:label "heart measurement" ;
  rdfs:comment "This is not the same term as the original \"heart measurement\".  That term is now \"heart morphological measurement\"." ;
  rdfs:subClassOf obo:CMO_0000001 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#International_League_Against_Epilepsy_classification> a rdfs:Class ;
  rdfs:label "International League Against Epilepsy classification" ;
  rdfs:subClassOf obo:NCIT_C20993 .

obo:NCIT_C86022 a rdfs:Class ;
  rdfs:label "Comprehension" ;
  rdfs:comment "An ability to understand the meaning or importance of something (or the knowledge acquired as a result)." ;
  rdfs:subClassOf obo:MF_0000020 .

obo:DOID_5419 a rdfs:Class ;
  rdfs:label "schizophrenia" ;
  rdfs:comment "A psychotic disorder that is characterized by a disintegration of thought processes and of emotional responsiveness." ;
  rdfs:seeAlso <http://www.case.edu/EpSO.owl#Schizophrenia> ;
  rdfs:subClassOf obo:DOID_2468 .

obo:HP_0011799 a rdfs:Class ;
  rdfs:label "Abnormality of facial soft tissue" ;
  rdfs:subClassOf obo:HP_0000271 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#unknown_etiology> a rdfs:Class ;
  rdfs:label "unknown etiology" ;
  rdfs:subClassOf obo:NCIT_C16390 .

obo:NBO_0000313 a rdfs:Class ;
  rdfs:label "behavior process" ;
  rdfs:comment "\"The action, reaction, or performance of an organism in response to external or internal stimuli.\" [GO:GO\\:0007610]" ;
  rdfs:subClassOf obo:OGMS_0000060 .

obo:DOID_326 a rdfs:Class ;
  rdfs:label "ischemia" ;
  rdfs:comment "A vascular disease that is characterized by a restriction in blood supply to tissues." ;
  rdfs:subClassOf obo:DOID_178 .

obo:IAO_0000109 a rdfs:Class ;
  rdfs:label "measurement datum" ;
  rdfs:comment "A measurement datum is an information content entity that is a recording of the output of a measurement such as produced by a device." ;
  rdfs:subClassOf obo:IAO_0000027 .

obo:SYMP_0000582 a rdfs:Class ;
  rdfs:label "hypersomnia" ;
  rdfs:comment "Hypersomnia is a sleep disturbance characterized by sleeping for excessive periods at intervals with intervening periods of normal duration of sleeping and waking." ;
  rdfs:seeAlso <https://www.ajmc.com/conferences/sleep-2013/epilepsy-and-sleep-defining-the-relationship> , <http://www.case.edu/EpSO.owl#Hypersomnia> ;
  rdfs:subClassOf obo:SYMP_0000566 .

obo:DOID_0060036 a rdfs:Class ;
  rdfs:label "intrinsic cardiomyopathy" ;
  rdfs:comment "A cardiomyopathy that is characterized as weakness in the muscle of the heart that is not due to an identifiable external cause." ;
  rdfs:subClassOf obo:DOID_0050700 .

obo:DOID_28 a rdfs:Class ;
  rdfs:label "endocrine system disease" ;
  rdfs:comment "A disease of anatomical entity that is located_in endocrine glands which secretes a type of hormone directly into the bloodstream to regulate the body." ;
  rdfs:subClassOf obo:DOID_7 .

obo:SYMP_0000537 a rdfs:Class ;
  rdfs:label "cyanosis" ;
  rdfs:comment "Cyanosis is a skin and integumentary tissue symptom characterized as a bluish or purplish discoloration (as of skin) due to deficient oxygenation of the blood." ;
  rdfs:seeAlso <https://www.epilepsy.com/connect/forums/living-epilepsy-adults/cyanosis> ;
  rdfs:subClassOf obo:SYMP_0000488 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#penicillin_model> a rdfs:Class ;
  rdfs:label "penicillin model" ;
  rdfs:subClassOf <https://bio.scai.fraunhofer.de/ontology/epilepsy#convulsant_drug_model> .

obo:NCIT_C2959 a rdfs:Class ;
  rdfs:label "Complication" ;
  rdfs:comment "Any disease or disorder that occurs during the course of, or because of, another disease, treatment, or procedure." ;
  rdfs:subClassOf obo:DOID_4 .

obo:HP_0011121 a rdfs:Class ;
  rdfs:label "Abnormality of skin morphology" ;
  rdfs:comment "Any morphological abnormality of the skin." ;
  rdfs:subClassOf obo:HP_0000951 .

obo:DOID_1926 a rdfs:Class ;
  rdfs:label "Gaucher's disease" ;
  rdfs:comment "A sphingolipidosis characterized by deficiency of the enzyme glucocerebrosidase which results in the accumulation of harmful quantities of the glycolipid glucocerebroside throughout the body, especially within the bone marrow, spleen and liver." ;
  rdfs:seeAlso <https://www.epilepsy.com/learn/professionals/co-existing-disorders/metabolic-disorders/inborn-errors/gauchers-disease> ;
  rdfs:subClassOf obo:DOID_1927 .

obo:NCIT_C15186 a rdfs:Class ;
  rdfs:label "Biofeedback" ;
  rdfs:comment "A training technique in which various bodily functions, such as heart rate, skin temperature, muscle tension, and brain activity are monitored so that people can learn to control them voluntarily so as to improve their health and physical performance." ;
  rdfs:subClassOf obo:NCIT_C15308 .

obo:SYMP_0000396 a rdfs:Class ;
  rdfs:label "mydriasis" ;
  rdfs:subClassOf obo:SYMP_0000254 .

obo:DOID_1768 a rdfs:Class ;
  rdfs:label "conversion disorder" ;
  rdfs:comment "A somatoform disorder that involves numbness, blindness, paralysis or fits without a neurological cause." ;
  rdfs:subClassOf obo:DOID_4737 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#beta-carboline_model> a rdfs:Class ;
  rdfs:label "beta-carboline model" ;
  rdfs:subClassOf <https://bio.scai.fraunhofer.de/ontology/epilepsy#convulsant_drug_model> .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#generalized_non_convulsive_status_epilepticus_without_coma> a rdfs:Class ;
  rdfs:label "generalized non convulsive status epilepticus without coma" ;
  rdfs:subClassOf obo:HP_0032671 .

obo:NCIT_C87089 a rdfs:Class ;
  rdfs:label "Irregular Respiration" ;
  rdfs:comment "A change from the normal breathing pattern in an infant, child, or adult, in terms of the amplitude and frequency of inhalations and exhalations." ;
  rdfs:subClassOf obo:SYMP_0000598 .

obo:DOID_3331 a rdfs:Class ;
  rdfs:label "frontal lobe epilepsy" ;
  rdfs:seeAlso <http://www.case.edu/EpSO.owl#FrontalLobeEpilepsy> ;
  rdfs:subClassOf obo:DOID_1826 .

obo:HP_0001371 a rdfs:Class ;
  rdfs:label "Flexion contracture" ;
  rdfs:comment "A flexion contracture is a bent (flexed) joint that cannot be straightened actively or passively. It is thus a chronic loss of joint motion due to structural changes in muscle, tendons, ligaments, or skin that prevents normal movement of joints." ;
  rdfs:subClassOf obo:HP_0003549 , obo:HP_0011729 , obo:HP_0011805 , obo:HP_0100261 .

obo:DOID_0050451 a rdfs:Class ;
  rdfs:label "Brugada syndrome" ;
  rdfs:comment "A heart conduction disease that is characterized by abnormal electrocardiogram (ECG) findings and an increased risk of sudden cardiac death." ;
  rdfs:subClassOf obo:DOID_0050177 , obo:DOID_10273 .

obo:NCIT_C69023 a rdfs:Class ;
  rdfs:label "Miscellaneous" ;
  rdfs:comment "Diverse, mixed, consisting of an assortment of different kinds." ;
  rdfs:seeAlso <https://www.epilepsydiagnosis.org/epilepsy-imitators.html#misc> ;
  rdfs:subClassOf <https://bio.scai.fraunhofer.de/ontology/epilepsy#epilepsy_imitator> .

obo:NBO_0000065 a rdfs:Class ;
  rdfs:label "consciousness behavior" ;
  rdfs:comment "\"Behavior related to a variety of aspects of the relationship between the mind and the world with which it interacts.\" [wikipedia:Consciousness]" ;
  rdfs:seeAlso <https://www.epilepsybehavior.com/article/S1525-5050(13)00484-8/fulltext> ;
  rdfs:subClassOf obo:NBO_0000313 .

obo:HP_0011167 a rdfs:Class ;
  rdfs:label "Focal tonic seizures" ;
  rdfs:comment "Seizures with sustained increase in muscle contraction in parts of the body lasting a few seconds to minutes." ;
  rdfs:seeAlso <https://www.epilepsy.com/learn/types-seizures/tonic-seizures> ;
  rdfs:subClassOf obo:HP_0011153 .

obo:HP_0002013 a rdfs:Class ;
  rdfs:label "Vomiting" ;
  rdfs:comment "Forceful ejection of the contents of the stomach through the mouth by means of a series of involuntary spasmic contractions." ;
  rdfs:subClassOf obo:HP_0002017 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#posterior_temporal_epilepsy> a rdfs:Class ;
  rdfs:label "posterior temporal epilepsy" ;
  rdfs:seeAlso <http://www.case.edu/EpSO.owl#PosteriorTemporalEpilepsy> , <http://www.case.edu/EpSO.owl#BasalTemporalEpilepsy> ;
  rdfs:subClassOf obo:DOID_3328 .

obo:OMIT_0027574 a rdfs:Class ;
  rdfs:label "Cerebral Small Vessel Diseases" ;
  rdfs:subClassOf obo:DOID_6713 .

obo:DOID_557 a rdfs:Class ;
  rdfs:label "kidney disease" ;
  rdfs:comment "A urinary system disease that is located_in the kidney." ;
  rdfs:seeAlso <https://www.epilepsy.com/learn/professionals/co-existing-disorders/renal-disorders> ;
  rdfs:subClassOf obo:DOID_18 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#fragmentary_behavior> a rdfs:Class ;
  rdfs:label "fragmentary behavior" ;
  rdfs:subClassOf obo:SYMP_0019182 .

obo:HP_0000364 a rdfs:Class ;
  rdfs:label "Hearing abnormality" ;
  rdfs:comment "An abnormality of the sensory perception of sound." ;
  rdfs:subClassOf obo:HP_0031704 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#corneal_kindling> a rdfs:Class ;
  rdfs:label "corneal kindling" ;
  rdfs:subClassOf obo:OMIT_0008800 .

obo:DOID_13148 a rdfs:Class ;
  rdfs:label "acute cystitis" ;
  rdfs:comment "A cystitis characterized by a sudden onset or severe symptoms." ;
  rdfs:subClassOf obo:DOID_1679 .

obo:GO_0022600 a rdfs:Class ;
  rdfs:label "digestive system process" ;
  rdfs:comment "A physical, chemical, or biochemical process carried out by living organisms to break down ingested nutrients into components that may be easily absorbed and directed into metabolism." ;
  rdfs:subClassOf obo:GO_0003008 .

obo:NCIT_C50465 a rdfs:Class ;
  rdfs:label "Asphyxia" ;
  rdfs:comment "A state of general hypoxia and hypercapnea, resulting in acidosis, which affects all tissues in the body." ;
  rdfs:subClassOf obo:OGMS_0000037 .

obo:DOID_3526 a rdfs:Class ;
  rdfs:label "cerebral infarction" ;
  rdfs:comment "A cerebrovascular disease that is characterized by an area of necrotic tissue in the brain resulting from a blockage or narrowing in the arteries supplying blood and oxygen to the brain." ;
  rdfs:seeAlso <http://www.case.edu/EpSO.owl#CerebralInfarction> ;
  rdfs:subClassOf obo:DOID_3454 .

obo:OMIT_0014676 a rdfs:Class ;
  rdfs:label "Theta Rhythm" ;
  rdfs:seeAlso <http://www.case.edu/EpSO.owl#ThetaActivity> , <https://emedicine.medscape.com/article/1139332-overview#a1> ;
  rdfs:subClassOf obo:OMIT_0027154 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#emetic_seizure> a rdfs:Class ;
  rdfs:label "emetic seizure" ;
  rdfs:seeAlso <http://www.case.edu/EpSO.owl#EmeticSeizure> ;
  rdfs:subClassOf obo:SYMP_0000124 .

obo:NBO_0000609 a rdfs:Class ;
  rdfs:label "visual hallucination" ;
  rdfs:comment "\"A form of hallucination that involves perceiving images without visual stimulus.\" [NBO:GVG]" ;
  rdfs:seeAlso <http://www.case.edu/EpSO.owl#Polyopia> ;
  rdfs:subClassOf obo:NBO_0000308 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#sz_mutant_hamster> a rdfs:Class ;
  rdfs:label "sz mutant hamster" ;
  rdfs:subClassOf <https://bio.scai.fraunhofer.de/ontology/epilepsy#paroxysmal_dystonia_model> .

obo:MF_0000019 a rdfs:Class ;
  rdfs:label "perception" ;
  rdfs:comment """a mental process which is a) produced by a causal process (for example involving light rays or air vibrations) involving a part of the environment of the organism, and b) is experienced by the organism as being so caused, and c) in
which the relevant part of the environment is thereby represented to the organism""" ;
  rdfs:subClassOf obo:MF_0000020 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#vertigo_aura> a rdfs:Class ;
  rdfs:label "vertigo aura" ;
  rdfs:subClassOf obo:SYMP_0000124 .

obo:DOID_1575 a rdfs:Class ;
  rdfs:label "rheumatic disease" ;
  rdfs:comment "An autoimmune hypersensitivity disease that involves inflammation or pain in the muscles, joints, or fibrous tissue." ;
  rdfs:subClassOf obo:DOID_0060032 , obo:DOID_65 .

obo:SYMP_0000399 a rdfs:Class ;
  rdfs:label "vertigo" ;
  rdfs:comment "Vertigo is a dizziness characterized by a specific type of dizziness, a major symptom of a balance disorder. It is the sensation of spinning or swaying while the body is stationary with respect to the surroundings." ;
  rdfs:subClassOf obo:SYMP_0000610 .

obo:MONDO_0003083 a rdfs:Class ;
  rdfs:label "venous hemangioma" ;
  rdfs:comment "A rare slow growing benign tumor of aberrant and ectatic venous connections." ;
  rdfs:seeAlso <http://www.case.edu/EpSO.owl#VenousAngioma> ;
  rdfs:subClassOf obo:DOID_1287 .

obo:RS_0000274 a rdfs:Class ;
  rdfs:label "GEPR" ;
  rdfs:subClassOf obo:RS_0000765 .

obo:DOID_1564 a rdfs:Class ;
  rdfs:label "fungal infectious disease" ;
  rdfs:comment "A disease by infectious agent that results_in infection, has_material_basis_in Fungi, which pass the resistance barriers of the human or animal body." ;
  rdfs:subClassOf obo:DOID_0050117 .

obo:SYMP_0000449 a rdfs:Class ;
  rdfs:label "cardiogenic shock" ;
  rdfs:seeAlso <https://www.epilepsy.com/learn/professionals/co-existing-disorders/cardiac-disorders> ;
  rdfs:subClassOf obo:SYMP_0000450 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#convulsive_status_epilepticus> a rdfs:Class ;
  rdfs:label "convulsive status epilepticus" ;
  rdfs:subClassOf obo:HP_0032658 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#sucking> a rdfs:Class ;
  rdfs:label "sucking" ;
  rdfs:subClassOf obo:NBO_0000705 .

obo:NBO_0000390 a rdfs:Class ;
  rdfs:label "primitive reflex" ;
  rdfs:comment "\"Reflex actions originating in the central nervous system that are exhibited by normal infants in response to particular stimuli.\" [wikipedia:Primitive_reflexes]" ;
  rdfs:subClassOf obo:NBO_0000389 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#spindle_stupor> a rdfs:Class ;
  rdfs:label "spindle stupor" ;
  rdfs:seeAlso <http://www.case.edu/EpSO.owl#SpindleStupor> ;
  rdfs:subClassOf <https://bio.scai.fraunhofer.de/ontology/epilepsy#special_pattern> .

obo:DOID_0060072 a rdfs:Class ;
  rdfs:label "benign neoplasm" ;
  rdfs:comment "A disease of cellular proliferation that results in abnormal growths in the body which lack the ability to metastasize." ;
  rdfs:subClassOf obo:DOID_14566 .

obo:NBO_0000575 a rdfs:Class ;
  rdfs:label "pilomotor reflex" ;
  rdfs:comment "\"A reflex that elucidates goose bumps (bumps on a person's skin at the base of body hairs) which may involuntarily develop when a person is cold or experiences strong emotions such as fear, awe, admiration or sexual arousal\" [wikipedia:Goose_bumps]" ;
  rdfs:subClassOf obo:NBO_0000389 .

obo:HP_0001279 a rdfs:Class ;
  rdfs:label "Syncope" ;
  rdfs:comment "Syncope refers to a generalized weakness of muscles with loss of postural tone, inability to stand upright, and loss of consciousness. Once the patient is in a horizontal position, blood flow to the brain is no longer hindered by gravitation and consciousness is regained. Unconsciousness usually lasts for seconds to minutes. Headache and drowsiness (which usually follow seizures) do not follow a syncopal attack. Syncope results from a sudden impairment of brain metabolism usually due to a reduction in cerebral blood flow." ;
  rdfs:seeAlso <https://www.epilepsydiagnosis.org/epilepsy-imitators.html#syncope> ;
  rdfs:subClassOf <https://bio.scai.fraunhofer.de/ontology/epilepsy#epilepsy_imitator> .

obo:NBO_0000101 a rdfs:Class ;
  rdfs:label "retropulsion" ;
  rdfs:comment "\"Moving backwards.\" [NBO:GVG]" ;
  rdfs:subClassOf obo:NBO_0000056 .

obo:SYMP_0000566 a rdfs:Class ;
  rdfs:label "sleep disturbance" ;
  rdfs:subClassOf obo:SYMP_0000567 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#spike_and_slow_wave_complex> a rdfs:Class ;
  rdfs:label "spike and slow wave complex" ;
  rdfs:subClassOf obo:HP_0025373 .

obo:DOID_2841 a rdfs:Class ;
  rdfs:label "asthma" ;
  rdfs:comment "A bronchial disease that is characterized by chronic inflammation and narrowing of the airways, which is caused by a combination of environmental and genetic factors. The disease has_symptom recurring periods of wheezing (a whistling sound while breathing), has_symptom chest tightness, has_symptom shortness of breath, has_symptom mucus production and has_symptom coughing. The symptoms appear due to a variety of triggers such as allergens, irritants, respiratory infections, weather changes, exercise, stress, reflux disease, medications, foods and emotional anxiety." ;
  rdfs:subClassOf obo:DOID_1176 .

obo:HP_0002411 a rdfs:Class ;
  rdfs:label "Myokymia" ;
  rdfs:comment "Myokymia consists of involuntary, fine, continuous, undulating contractions that spread across the affected striated muscle." ;
  rdfs:subClassOf obo:HP_0100022 .

obo:NBO_0000502 a rdfs:Class ;
  rdfs:label "somniloquy" ;
  rdfs:comment "\"A NREM parasomnia characterised by talking during sleep.\" [NBO:GVG]" ;
  rdfs:seeAlso <https://www.epilepsy.com/learn/challenges-epilepsy/sleep-and-epilepsy/sleep-disorders> , <http://www.case.edu/EpSO.owl#SleepTalking> ;
  rdfs:subClassOf obo:NBO_0000499 .

obo:HP_0002197 a rdfs:Class ;
  rdfs:label "Generalized-onset seizure" ;
  rdfs:comment "Seizures of with initial involvement of both cerebral hemispheres." ;
  rdfs:subClassOf <https://bio.scai.fraunhofer.de/ontology/epilepsy#seizure_classification> .

obo:NBO_0000079 a rdfs:Class ;
  rdfs:label "feeding behavior" ;
  rdfs:comment "The act of bringing an object or substance into the body by swallowing, surrounding or absorbing it [NBO:SMAC]" ;
  rdfs:subClassOf obo:NBO_0001845 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#polymorphic_wave> a rdfs:Class ;
  rdfs:label "polymorphic wave" ;
  rdfs:subClassOf obo:OMIT_0027154 .

obo:NCIT_C25347 a rdfs:Class ;
  rdfs:label "Height" ;
  rdfs:comment "The vertical measurement or distance from the base to the top of an object; the vertical dimension of extension." ;
  rdfs:subClassOf obo:NCIT_C19332 .

obo:MFOMD_0000123 a rdfs:Class ;
  rdfs:label "stupor" ;
  rdfs:comment """A state of unresponsiveness with immobility and mutism.


DSM-IV-TR (american Psychiatric Association)""" ;
  rdfs:subClassOf obo:MFOMD_0000024 .

obo:OMIABIS_0001008 a rdfs:Class ;
  rdfs:label "comorbidity" ;
  rdfs:comment "A diagnosis that is the outcome of a diagnostic process targeting a second or additional health problem." ;
  rdfs:subClassOf obo:OGMS_0000073 .

obo:DOID_8970 a rdfs:Class ;
  rdfs:label "subacute sclerosing panencephalitis" ;
  rdfs:comment "A viral infectious disease that results_in infection located_in brain and that  has_material_basis_in Measles virus which is immune resistant." ;
  rdfs:subClassOf obo:DOID_934 .

obo:DOID_0080001 a rdfs:Class ;
  rdfs:label "bone disease" ;
  rdfs:comment "A connective tissue disease that affects the structure or development of bone or causes an impairment of normal bone function." ;
  rdfs:subClassOf obo:DOID_65 .

obo:NCIT_C18280 a rdfs:Class ;
  rdfs:label "Cytogenetic Analysis" ;
  rdfs:comment "Techniques for analysis of chromosomal and subchromosomal properties and structures, such as those to diagnose, classify, screen for, or manage genetic diseases and abnormalities." ;
  rdfs:subClassOf obo:NCIT_C19770 .

obo:DOID_0050562 a rdfs:Class ;
  rdfs:label "West syndrome" ;
  rdfs:comment "An infancy electroclinical syndrome that is characterized by infantile spasms, hypsarrhythmia on electroencephalogram and intellectual disability." ;
  rdfs:subClassOf obo:MONDO_0100022 .

obo:NCIT_C20993 a rdfs:Class ;
  rdfs:label "Research or Clinical Assessment Tool" ;
  rdfs:comment "Any one of several evaluation/assessment tools used to ascertain a patient's condition or diagnosis." ;
  rdfs:subClassOf obo:NCIT_C18020 .

obo:HP_0002329 a rdfs:Class ;
  rdfs:label "Drowsiness" ;
  rdfs:comment "Excessive daytime sleepiness." ;
  rdfs:subClassOf obo:HP_0004372 .

obo:HP_0025144 a rdfs:Class ;
  rdfs:label "Shivering" ;
  rdfs:comment "Involuntary contraction or twitching of the muscles." ;
  rdfs:seeAlso <https://pdfs.semanticscholar.org/286d/427de14ed86a44160267f6a2c444afccf2a1.pdf> ;
  rdfs:subClassOf obo:HP_0025142 .

obo:DOID_646 a rdfs:Class ;
  rdfs:label "viral encephalitis" ;
  rdfs:comment "An encephalitis that involves inflammation of the brain caused by viral infection." ;
  rdfs:subClassOf <https://bio.scai.fraunhofer.de/ontology/epilepsy#infectious_etiology> .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#multiple_subpial_transection> a rdfs:Class ;
  rdfs:label "multiple subpial transection" ;
  rdfs:seeAlso <https://www.webmd.com/epilepsy/guide/multiple-subpial-transection-mst> ;
  rdfs:subClassOf obo:OMIABIS_0001041 .

obo:NCIT_C16866 a rdfs:Class ;
  rdfs:label "Model" ;
  rdfs:comment "A representation of something, often idealized or modified to make it conceptually easier to understand." ;
  rdfs:subClassOf obo:IAO_0000030 .

obo:DOID_4 a rdfs:Class ;
  rdfs:label "disease" ;
  rdfs:comment "A disease is a disposition (i) to undergo pathological processes that (ii) exists in an organism because of one or more disorders in that organism." ;
  rdfs:subClassOf obo:BFO_0000016 .

obo:OMIT_0005788 a rdfs:Class ;
  rdfs:label "Eidetic Imagery" ;
  rdfs:subClassOf obo:NCIT_C35470 .

obo:UBERON_0013558 a rdfs:Class ;
  rdfs:label "Brodmann (1909) area 27" ;
  rdfs:comment "Area 27 of Brodmann-1909 is a cytoarchitecturally defined cortical area that is a rostral part of the parahippocampal gyrus of the guenon (Brodmann-1909). It is commonly regarded as a synonym of presubiculum (Crosby-62). [WP,unvetted]." ;
  rdfs:subClassOf obo:UBERON_0013529 .

obo:MP_0004086 a rdfs:Class ;
  rdfs:label "absent heartbeat" ;
  rdfs:comment "lack of a spontaneously beating heart (usually due to defects in the calcium delivery mechanism or loss of a functional contractile apparatus)" ;
  rdfs:subClassOf obo:MP_0004085 .

obo:SYMP_0000529 a rdfs:Class ;
  rdfs:label "tachycardia" ;
  rdfs:comment "Tachycardia is a cardiovascular system symptom consisting of a relatively rapid heart action whether physiological (as after exercise) or pathological." ;
  rdfs:subClassOf obo:SYMP_0000287 .

obo:NCIT_C64345 a rdfs:Class ;
  rdfs:label "Cognitive Behavior Therapy" ;
  rdfs:comment "A type of psychotherapy utilized to treat different forms of mental disorders.The treatment involves the identification of unhelpful or destructive patterns of thinking and behaviors and the subsequent replacement with behaviors that are beneficial and constructive." ;
  rdfs:subClassOf obo:NCIT_C15308 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#flexor_spasm> a rdfs:Class ;
  rdfs:label "flexor spasm" ;
  rdfs:subClassOf obo:HP_0003394 .

obo:HP_0003111 a rdfs:Class ;
  rdfs:label "Abnormal blood ion concentration" ;
  rdfs:comment "Abnormality of the homeostasis (concentration) of a monoatomic ion." ;
  rdfs:subClassOf obo:HP_0032180 .

obo:DOID_12132 a rdfs:Class ;
  rdfs:label "granulomatosis with polyangiitis" ;
  rdfs:comment "An autoimmune hypersensitivity disease that is characterized by necrotizing granulomatous inflammation of the upper and lower respiratory tract, glomerulonephritis, vasculitis, and the presence of antineutrophil cytoplasmatic autoantibodies (ANCAs) in patient sera, and is located_in lung, located_in kidney, located_in skin resulting from an autoimmune attack by antineutrophil cytoplasmic antibodies against small and medium-size blood vessels." ;
  rdfs:seeAlso <https://www.epilepsy.com/learn/professionals/challenging-cases/granulomatosis-polyangiitis> ;
  rdfs:subClassOf obo:DOID_37 , obo:DOID_417 , obo:DOID_557 , obo:DOID_850 .

obo:UBERON_0001897 a rdfs:Class ;
  rdfs:label "dorsal plus ventral thalamus" ;
  rdfs:comment "Subcortical brain region consisting of paired gray matter bodies in the dorsal diencephalon and forming part of the lateral wall of the third ventricle of the brain. The thalamus represents the major portion of the diencephalon and is commonly divided into cellular aggregates known as nuclear groups.(MeSH). The dorsal topographic division of the interbrain. The macrodissected adult human thalamus was clearly illustrated by Vesalius in 1543 and the term as defined here was introduced by His in 1893. It includes the traditional epithalamus, dorsal thalamus, and ventral thalamus of Herrick (1910, pp. 494, 498). Also see Kuhlenbeck (1927, Ch. 9) and Jones (1985, p. 87)." ;
  rdfs:seeAlso <http://www.case.edu/EpSO.owl#ThalamusSegment> ;
  rdfs:subClassOf obo:UBERON_0002616 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#bifocal_encephalomalacia> a rdfs:Class ;
  rdfs:label "bifocal encephalomalacia" ;
  rdfs:seeAlso <http://www.case.edu/EpSO.owl#BifocalEncephalomalacia> ;
  rdfs:subClassOf obo:DOID_936 .

obo:HP_0031704 a rdfs:Class ;
  rdfs:label "Abnormal ear physiology" ;
  rdfs:comment "Any functional anomaly of the ear." ;
  rdfs:subClassOf obo:HP_0000598 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#Wada_test> a rdfs:Class ;
  rdfs:label "Wada test" ;
  rdfs:subClassOf obo:ERO_0001330 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#somatoform_dissociation_questionnaire> a rdfs:Class ;
  rdfs:label "somatoform dissociation questionnaire" ;
  rdfs:subClassOf obo:NCIT_C20993 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#music_hallucination> a rdfs:Class ;
  rdfs:label "music hallucination" ;
  rdfs:subClassOf obo:NBO_0000610 .

obo:GO_0060273 a rdfs:Class ;
  rdfs:label "crying behavior" ;
  rdfs:comment "The behavior in which an organism sheds tears, often accompanied by non-verbal vocalizations and in response to external or internal stimuli." ;
  rdfs:subClassOf obo:GO_0007610 .

obo:SYMP_0000598 a rdfs:Class ;
  rdfs:label "respiratory abnormality" ;
  rdfs:subClassOf obo:SYMP_0000514 .

obo:DOID_0111563 a rdfs:Class ;
  rdfs:label "Sturge-Weber syndrome" ;
  rdfs:comment "A vascular disease characterized by intracranial vascular anomaly, leptomeningeal angiomatosis, facial cutaneous vascular malformations, and glaucoma that has_material_basis_in somatic mutation in GNAQ on chromosome 9q21.2." ;
  rdfs:subClassOf obo:MONDO_0024291 .

obo:DOID_2548 a rdfs:Class ;
  rdfs:label "reflex epilepsy" ;
  rdfs:comment "A variable age at onset electroclinical syndrome that is consistently induced by identifiable and objective-specific triggers, which may be an afferent stimulus or by the patient's own activity." ;
  rdfs:subClassOf obo:MONDO_0100036 .

obo:UBERON_0000479 a rdfs:Class ;
  rdfs:label "tissue" ;
  rdfs:comment "Multicellular anatomical structure that consists of many cells of one or a few types, arranged in an extracellular matrix such that their long-range organisation is at least partly a repetition of their short-range organisation." ;
  rdfs:subClassOf obo:UBERON_0010000 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#SCN8A-related_epilepsy_with_encephalopathy> a rdfs:Class ;
  rdfs:label "SCN8A-related epilepsy with encephalopathy" ;
  rdfs:subClassOf obo:DOID_225 .

obo:HP_0010978 a rdfs:Class ;
  rdfs:label "Abnormality of immune system physiology" ;
  rdfs:comment "A functional abnormality of the immune system." ;
  rdfs:subClassOf obo:HP_0002715 .

obo:PW_0000848 a rdfs:Class ;
  rdfs:label "gamma-aminobutyric acid signaling pathway" ;
  rdfs:comment "Gamma-aminobutyric acid signals at inhibitory synapses via the type A receptor, which is part of a ligand-gated ion channel and the type B receptors which are metabotropic, G protein-coupled receptors." ;
  rdfs:subClassOf obo:GO_0007165 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#electrocerebral_inactivity> a rdfs:Class ;
  rdfs:label "electrocerebral inactivity" ;
  rdfs:seeAlso <http://www.case.edu/EpSO.owl#ElectrocerebralInactivity> ;
  rdfs:subClassOf <https://bio.scai.fraunhofer.de/ontology/epilepsy#special_pattern> .

obo:NCIT_C21024 a rdfs:Class ;
  rdfs:label "Deep Brain Stimulation" ;
  rdfs:comment "A highly invasive form of electroanalgesia mainly used in the management of debilitating chronic pain syndromes after all other less invasive therapeutic modalities (including SCS) have failed. (White, Li, and Chiu)" ;
  rdfs:subClassOf obo:OGMS_0000112 .

obo:HP_0002307 a rdfs:Class ;
  rdfs:label "Drooling" ;
  rdfs:comment "Habitual flow of saliva out of the mouth." ;
  rdfs:subClassOf obo:HP_0000708 , obo:HP_0003781 .

obo:HP_0032049 a rdfs:Class ;
  rdfs:label "Focal cortical dysplasia type Ib" ;
  rdfs:comment "A subtype of focal cortical dysplasia type I that is characterized by abnormal tangential cortical lamination." ;
  rdfs:seeAlso <http://www.case.edu/EpSO.owl#FocalCorticalDysplasiaTypeIB> ;
  rdfs:subClassOf obo:HP_0032047 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#dorsolateral_frontal_cortex> a rdfs:Class ;
  rdfs:label "dorsolateral frontal cortex" ;
  rdfs:subClassOf <https://bio.scai.fraunhofer.de/ontology/epilepsy#frontal_lobe_seizure> .

obo:HP_0004418 a rdfs:Class ;
  rdfs:label "Thrombophlebitis" ;
  rdfs:comment "Inflammation of a vein associated with venous thrombosis (blood clot formation within the vein)." ;
  rdfs:seeAlso <https://www.longdom.org/open-access/a-case-of-thrombophlebitis-caused-by-carbamazepine-2161-1025.1000121.pdf> ;
  rdfs:subClassOf obo:HP_0004936 .

obo:MFOMD_0000101 a rdfs:Class ;
  rdfs:label "delusion" ;
  rdfs:comment """
Erroneous beliefs that usually involve a misinterpretation of perceptions or experiences. (their content may include a variety of themes (e.g., persecutory, referential, somatic, religious, or grandiose).


DSM-IV-TR (american Psychiatric Association)""" ;
  rdfs:subClassOf obo:MFOMD_0000024 .

obo:DOID_0060047 a rdfs:Class ;
  rdfs:label "writing disorder" ;
  rdfs:comment "A learning disability that involves impaired written language ability such as impairments in handwriting, spelling, organization of ideas, and composition." ;
  rdfs:subClassOf obo:DOID_8927 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#amygdala_kindling> a rdfs:Class ;
  rdfs:label "amygdala kindling" ;
  rdfs:subClassOf <https://bio.scai.fraunhofer.de/ontology/epilepsy#pharmacoresistant_epilepsy_model> .

obo:OBI_0000626 a rdfs:Class ;
  rdfs:label "DNA sequencing" ;
  rdfs:comment "DNA sequencing is a sequencing process which uses deoxyribonucleic acid as input and results in a the creation of DNA sequence information artifact using a DNA sequencer instrument." ;
  rdfs:subClassOf obo:ERO_0001286 .

obo:DOID_4540 a rdfs:Class ;
  rdfs:label "dysgraphia" ;
  rdfs:comment "A writing disorder that involves a deficiency in the ability to write where the writing is distorted or incorrect, spelling difficulty, poor handwriting or trouble putting thoughts on paper." ;
  rdfs:seeAlso <https://www.epilepsydiagnosis.org/seizure/cognitive-overview.html> ;
  rdfs:subClassOf obo:DOID_0060047 .

obo:OBI_1110049 a rdfs:Class ;
  rdfs:label "allergy" ;
  rdfs:comment "is a disease in which an abnormally strong inflammatory immune response is triggered against non-self entities, and the immune response has no protective effect" ;
  rdfs:subClassOf obo:HP_0010978 .

obo:DOID_3454 a rdfs:Class ;
  rdfs:label "brain infarction" ;
  rdfs:comment "A cerebrovascular disease that is characterized by tissue necrosis located_in the brain, resulting from inadequate blood flow through the brain." ;
  rdfs:subClassOf obo:DOID_6713 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#El_mouse> a rdfs:Class ;
  rdfs:label "El mouse" ;
  rdfs:subClassOf obo:NCIT_C19272 .

obo:DOID_10933 a rdfs:Class ;
  rdfs:label "obsessive-compulsive disorder" ;
  rdfs:comment "An anxiety disorder that involves unwanted and repeated thoughts, feelings, ideas, sensations (obsessions), or behaviors that make them feel driven to do something (compulsions)." ;
  rdfs:subClassOf obo:DOID_2030 .

obo:HP_0011163 a rdfs:Class ;
  rdfs:label "Somatosensory auras" ;
  rdfs:comment "Auras with sensation of tingling, numbness, electric shock sensations, pain, sense of movement, or desire to move." ;
  rdfs:subClassOf obo:HP_0011157 .

obo:NBO_0000001 a rdfs:Class ;
  rdfs:label "body part movement" ;
  rdfs:comment "A change of place or position of part of an organism that does not involve the entire organism [NBO:SMAC]" ;
  rdfs:subClassOf obo:NBO_0000338 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#elementary_partial_seizure> a rdfs:Class ;
  rdfs:label "elementary partial seizure" ;
  rdfs:subClassOf obo:SYMP_0000124 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#amnestic_seizure> a rdfs:Class ;
  rdfs:label "amnestic seizure" ;
  rdfs:seeAlso <http://www.case.edu/EpSO.owl#AmnesticSeizure> ;
  rdfs:subClassOf <https://bio.scai.fraunhofer.de/ontology/epilepsy#special_seizure> .

<https://bio.scai.fraunhofer.de/ontology/0000506> a rdfs:Class ;
  rdfs:label "epileptic seizure network" ;
  rdfs:subClassOf <https://bio.scai.fraunhofer.de/ontology/0000505> .

obo:NCIT_C84973 a rdfs:Class ;
  rdfs:label "Orthostatic Intolerance" ;
  rdfs:comment "A condition characterized by development of symptoms while standing. It is an autonomic nervous system disorder and the symptoms are relieved once the person sits back down. Symptoms include heart palpitations, sweating, anxiety, lightheadedness, hyperpnea, anxiety, and blurred vision." ;
  rdfs:subClassOf obo:HP_0001279 .

obo:NCBITaxon_1 a rdfs:Class ;
  rdfs:label "root" ;
  rdfs:subClassOf obo:BFO_0000040 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#familial_(autosomal_dominant)_focal_epilepsy> a rdfs:Class ;
  rdfs:label "familial (autosomal dominant) focal epilepsy" ;
  rdfs:subClassOf obo:DOID_1826 .

obo:HP_0032251 a rdfs:Class ;
  rdfs:label "Abnormal immune system morphology" ;
  rdfs:subClassOf obo:HP_0002715 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#non-invasive_epileptic_focus_localization> a rdfs:Class ;
  rdfs:label "non-invasive epileptic focus localization" ;
  rdfs:subClassOf <https://bio.scai.fraunhofer.de/ontology/epilepsy#non-invasive_preoperative_evaluation> .

obo:DOID_1176 a rdfs:Class ;
  rdfs:label "bronchial disease" ;
  rdfs:comment "A lower respiratory tract disease that affects the airways leading into the lungs, which is caused due to inflammation of the bronchi and bronchioles, infection, or blockage." ;
  rdfs:subClassOf obo:DOID_0050161 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#bilateral_periodic_lateralized_epileptiform_discharge> a rdfs:Class ;
  rdfs:label "bilateral periodic lateralized epileptiform discharge" ;
  rdfs:seeAlso <http://www.case.edu/EpSO.owl#Bi-PeriodicLateralizedEpileptiformDischarge> ;
  rdfs:subClassOf obo:HP_0025373 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#right_fronto_temporal_glioma> a rdfs:Class ;
  rdfs:label "right fronto temporal glioma" ;
  rdfs:seeAlso <http://www.case.edu/EpSO.owl#RightFrontoTemporalGlioma> ;
  rdfs:subClassOf obo:DOID_0060108 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#compulsive_valsalva> a rdfs:Class ;
  rdfs:label "compulsive valsalva" ;
  rdfs:subClassOf obo:HP_0001279 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#posterior_cingulate_epilepsy> a rdfs:Class ;
  rdfs:label "posterior cingulate epilepsy" ;
  rdfs:seeAlso <http://www.case.edu/EpSO.owl#PosteriorCingulateEpilepsy> ;
  rdfs:subClassOf <https://bio.scai.fraunhofer.de/ontology/epilepsy#cingulate_epilepsy> .

obo:OMIT_0009194 a rdfs:Class ;
  rdfs:label "Liver Function Tests" ;
  rdfs:seeAlso <https://www.webmd.com/epilepsy/guide/epilepsy-blood-test> ;
  rdfs:subClassOf obo:OBI_0000070 .

obo:NCIT_C118305 a rdfs:Class ;
  rdfs:label "Macropsia" ;
  rdfs:comment "An alteration in visual perception that causes objects to appear larger than their actual size." ;
  rdfs:seeAlso <http://www.case.edu/EpSO.owl#Macropsia> , <https://www.epilepsy.com/connect/forums/living-epilepsy-adults/macropsia-things-feeling-larger-they-are> ;
  rdfs:subClassOf obo:HP_0000504 .

obo:NBO_0000711 a rdfs:Class ;
  rdfs:label "drug withdrawal induced seizure" ;
  rdfs:comment "\"A type of seizure induced by termination of drug administration.\" [NBO:GVG]" ;
  rdfs:subClassOf obo:NBO_0000709 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#Subclinical_Rhythmical_Discharges_of_Adults> a rdfs:Class ;
  rdfs:label "subclinical rhythmical discharge of adults" ;
  rdfs:seeAlso <http://www.case.edu/EpSO.owl#SubclinicalRhythmicElectrographicDischargesinAdult> ;
  rdfs:subClassOf <https://bio.scai.fraunhofer.de/ontology/epilepsy#rhythmic_benign_variant> .

obo:HP_0011159 a rdfs:Class ;
  rdfs:label "Epigastric auras" ;
  rdfs:comment "Auras with abdominal discomfort including nausea, emptiness, tightness, churning, butterflies, malaise, pain, and hunger; sensation may rise to chest or throat. Some phenomena may reflect ictal autonomic dysfunction." ;
  rdfs:subClassOf obo:SYMP_0000124 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#flash> a rdfs:Class ;
  rdfs:label "flash" ;
  rdfs:seeAlso <https://www.healthline.com/health/seeing-stars-in-vision> , <https://www.aao.org/eye-health/symptoms/flashes-of-light> ;
  rdfs:subClassOf <https://bio.scai.fraunhofer.de/ontology/epilepsy#positive_visual_hallucination> .

obo:HP_0032316 a rdfs:Class ;
  rdfs:label "Family history" ;
  rdfs:comment "Information about close relatives of an individual who is the proband of a study or who is being investigated with the goal of identifying a medical diagnosis. Usually, the family history includes information from three generations of relatives, including children, brothers and sisters, parents, aunts and uncles, nieces and nephews, grandparents, and cousins." ;
  rdfs:seeAlso <https://www.webmd.com/epilepsy/epilepsy-common-causes#1> ;
  rdfs:subClassOf obo:OGMS_0000015 .

obo:DOID_5295 a rdfs:Class ;
  rdfs:label "intestinal disease" ;
  rdfs:comment "A gastrointestinal system disease that is located_in the intestine." ;
  rdfs:subClassOf obo:DOID_77 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#autosomal-dominant_lateral_temporal_lobe_epilepsy_model> a rdfs:Class ;
  rdfs:label "autosomal-dominant lateral temporal lobe epilepsy model" ;
  rdfs:subClassOf <https://bio.scai.fraunhofer.de/ontology/epilepsy#chemical_mutagenesis_derived_model> .

obo:UBERON_0013573 a rdfs:Class ;
  rdfs:label "Brodmann (1909) area 40" ;
  rdfs:comment "Brodmann area 40, or BA40, is part of the parietal cortex in the human brain. The inferior part of BA40 is in the area of the supramarginal gyrus, which lies at the posterior end of the lateral fissure, in the inferior lateral part of the parietal lobe. It is bounded approximately by the intraparietal sulcus, the inferior postcentral sulcus, the posterior subcentral sulcus and the lateral sulcus. Cytoarchitecturally it is bounded caudally by the angular area 39 (H), rostrally and dorsally by the caudal postcentral area 2, and ventrally by the subcentral area 43 and the superior temporal area 22 (Brodmann-1909). Cytoarchitectonically defined subregions of rostral BA40/the supramarginal gyrus are PF, PFcm, PFm, PFop, and PFt. Area PF is the homologue to macaque area PF, part of the mirror neuron system, and active in humans during imitation. The supramarginal gyrus part of Brodmann area 40 is the region in the inferior parietal lobe that is involved in reading both in regards to meaning and phonology. [WP,unvetted]." ;
  rdfs:subClassOf obo:UBERON_0013529 .

obo:NCIT_C80519 a rdfs:Class ;
  rdfs:label "Biological Model" ;
  rdfs:comment "Systems designed to elucidate facts about complex biological phenomena, usually in a less complex or theoretical test environment." ;
  rdfs:subClassOf obo:NCIT_C16866 .

obo:HP_0012001 a rdfs:Class ;
  rdfs:label "EEG with generalized polyspikes" ;
  rdfs:comment "EEG with repetitive generalized sharp transient waves of a duration less than 80 msec." ;
  rdfs:seeAlso <http://www.case.edu/EpSO.owl#PolySpike> ;
  rdfs:subClassOf obo:HP_0011198 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#second_line_immunotherapy> a rdfs:Class ;
  rdfs:label "second line immunotherapy" ;
  rdfs:seeAlso <https://www.j-epilepsy.org/journal/view.php?number=151> ;
  rdfs:subClassOf obo:OGMS_0000114 .

obo:DOID_0060038 a rdfs:Class ;
  rdfs:label "specific developmental disorder" ;
  rdfs:comment "A developmental disorder of mental health that categorizes specific learning disabilities and developmental disorders affecting coordination." ;
  rdfs:subClassOf obo:DOID_0060037 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#hypnogogic_seizure> a rdfs:Class ;
  rdfs:label "hypnogogic seizure" ;
  rdfs:seeAlso <http://www.columbianeurology.org/sites/default/files/nocturnal_seizures_SemNeurol_2004.pdf> , <http://www.case.edu/EpSO.owl#HypnogogicSeizure> ;
  rdfs:subClassOf <https://bio.scai.fraunhofer.de/ontology/epilepsy#special_seizure> .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#transient> a rdfs:Class ;
  rdfs:label "transient" ;
  rdfs:seeAlso <https://www.medicine.mcgill.ca/physio/vlab/biomed_signals/eeg_n.htm> ;
  rdfs:subClassOf obo:OMIT_0027154 .

obo:NCIT_C103517 a rdfs:Class ;
  rdfs:label "Epworth Sleepiness Scale Questionnaire" ;
  rdfs:comment "A standardized rating scale used to assess an individual's general level of daytime sleepiness." ;
  rdfs:subClassOf obo:NCIT_C91105 .

obo:MONDO_0017409 a rdfs:Class ;
  rdfs:label "fetal cytomegalovirus syndrome" ;
  rdfs:comment "An infection with the Cytomegalovirus that is present from birth." ;
  rdfs:subClassOf obo:MONDO_0005132 .

obo:HP_0010845 a rdfs:Class ;
  rdfs:label "EEG with generalized slow activity" ;
  rdfs:comment "Diffuse slowing of cerebral electrical activity recorded along the scalp by electroencephalography (EEG)." ;
  rdfs:seeAlso <http://www.case.edu/EpSO.owl#SlowActivity> ;
  rdfs:subClassOf obo:HP_0011203 .

obo:NCIT_C114781 a rdfs:Class ;
  rdfs:label "Dialysis Disequilibrium Syndrome" ;
  rdfs:comment "A complication occurring during hemodialysis that is thought to be due to a rapid decrease in blood urea nitrogen, and is characterized by an increase in intracranial pressure resulting in nausea, headache, vomiting, restlessness, and/or a decreased level of consciousness." ;
  rdfs:seeAlso <https://www.epilepsy.com/learn/professionals/co-existing-disorders/renal-disorders/dialysis-disequilibrium-syndrome> ;
  rdfs:subClassOf obo:DOID_225 .

obo:RS_0004561 a rdfs:Class ;
  rdfs:label "SD-GEPR-3" ;
  rdfs:subClassOf obo:RS_0000765 .

<https://bio.scai.fraunhofer.de/ontology/0000503> a rdfs:Class ;
  rdfs:label "brain connectivity" ;
  rdfs:subClassOf <https://bio.scai.fraunhofer.de/ontology/0000500> .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#epileptiform_benign_variant> a rdfs:Class ;
  rdfs:label "epileptiform benign variant" ;
  rdfs:seeAlso <http://www.case.edu/EpSO.owl#EpileptiformBenignVariant> ;
  rdfs:subClassOf <https://bio.scai.fraunhofer.de/ontology/epilepsy#benign_EEG_pattern> .

obo:HP_0001336 a rdfs:Class ;
  rdfs:label "Myoclonus" ;
  rdfs:comment "Very brief, involuntary random muscular contractions occurring at rest, in response to sensory stimuli, or accompanying voluntary movements." ;
  rdfs:subClassOf obo:HP_0004305 .

obo:SYMP_0019163 a rdfs:Class ;
  rdfs:label "eye symptom" ;
  rdfs:subClassOf obo:SYMP_0000387 .

obo:UBERON_0004923 a rdfs:Class ;
  rdfs:label "organ component layer" ;
  rdfs:comment "A part of a wall of an organ that forms a layer." ;
  rdfs:subClassOf obo:UBERON_0000064 .

<https://bio.scai.fraunhofer.de/ontology/0000417> a rdfs:Class ;
  rdfs:label "anatomical entity TM_BIN" ;
  rdfs:comment "The 'anatomical entity TM_BIN' concept enables a compilation of diverse concepts that are related to anatomical entities in Epilepsy via the Axiome 'isAnatomicalEntityFor some epilepsy'.  Thus enables the adaptation of the ontology for text mining purposes for Epilepsy related information retrieval and information extraction." .

obo:HP_0004325 a rdfs:Class ;
  rdfs:label "Decreased body weight" ;
  rdfs:comment "Abnormally low body weight." ;
  rdfs:subClassOf obo:HP_0004323 .

obo:ERO_0002016 a rdfs:Class ;
  rdfs:label "whole genome sequencing" ;
  rdfs:comment "A genotyping assay that determines the complete DNA sequence of a cell or organism's genome at a single time." ;
  rdfs:subClassOf obo:ERO_0001286 .

obo:DOID_8869 a rdfs:Class ;
  rdfs:label "neuromyelitis optica" ;
  rdfs:comment "A central nervous system disease characterized by inflammation of the optic nerve (optic neuritis) and inflammation of the spinal cord (myelitis)." ;
  rdfs:subClassOf obo:DOID_0060004 , obo:DOID_0060033 , obo:DOID_1891 , obo:DOID_319 .

obo:DOID_0050013 a rdfs:Class ;
  rdfs:label "carbohydrate metabolism disease" ;
  rdfs:comment "An acquired metabolic disease that is characterized by abnormal carbohydrate metabolism." ;
  rdfs:subClassOf obo:DOID_0060158 .

obo:HP_0002392 a rdfs:Class ;
  rdfs:label "EEG with polyspike wave complexes" ;
  rdfs:comment "The presence of complexes of repetitive spikes and waves in EEG." ;
  rdfs:subClassOf obo:HP_0010850 .

obo:NCIT_C9505 a rdfs:Class ;
  rdfs:label "Dysembryoplastic Neuroepithelial Tumor" ;
  rdfs:comment "A benign glial-neuronal neoplasm. It is usually supratentorial, located, generally, in the cortex and occurs in children and young adults with a long-standing history of partial seizures. A histologic hallmark of this tumor is the 'specific glioneuronal element', characterized by columns, made up of bundles of axons, oriented perpendicularly to the cortical surface. (Adapted from WHO)" ;
  rdfs:subClassOf obo:HP_0002664 .

obo:UBERON_0013533 a rdfs:Class ;
  rdfs:label "Brodmann (1909) area 2" ;
  rdfs:subClassOf obo:UBERON_0013529 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#mini-international_neuropsychiatric_interview> a rdfs:Class ;
  rdfs:label "mini-international neuropsychiatric interview" ;
  rdfs:subClassOf obo:NCIT_C20993 .

obo:DOID_1969 a rdfs:Class ;
  rdfs:label "cerebral palsy" ;
  rdfs:comment "A brain disease that is caused by damage to the motor control centers of the developing brain during pregnancy, during childbirth or after birth, which affects muscle movement and balance." ;
  rdfs:seeAlso <http://www.case.edu/EpSO.owl#CerebralPalsy> ;
  rdfs:subClassOf obo:DOID_936 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#occipital_intermittent_rhythmic_delta_activity> a rdfs:Class ;
  rdfs:label "occipital intermittent rhythmic delta activity" ;
  rdfs:seeAlso <http://www.case.edu/EpSO.owl#OccipitalIntermittentRythmicDeltaActivity> ;
  rdfs:subClassOf obo:HP_0002353 .

obo:UBERON_0006475 a rdfs:Class ;
  rdfs:label "Brodmann (1909) area 31" ;
  rdfs:comment "Brodmann area 31, also known as dorsal posterior cingulate area 31, is a subdivision of the cytoarchitecturally defined cingulate region of the cerebral cortex. In the human it occupies portions of the posterior cingulate gyrus and medial aspect of the parietal lobe. Approximate boundaries are the cingulate sulcus dorsally and the parieto-occipital sulcus caudally. It partially surrounds the subparietal sulcus, the ventral continuation of the cingulate sulcus in the parietal lobe. Cytoarchitecturally it is bounded rostrally by the ventral anterior cingulate area 24, ventrally by the ventral posterior cingulate area 23, dorsally by the gigantopyramidal area 4 and preparietal area 5 and caudally by the superior parietal area 7 (H) (Brodmann-1909)." ;
  rdfs:subClassOf obo:UBERON_0013529 .

obo:HP_0030914 a rdfs:Class ;
  rdfs:label "Abnormal peristalsis" ;
  rdfs:comment "An anomaly of the wave-like muscle contractions of the digestive tract." ;
  rdfs:subClassOf obo:HP_0002579 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#methoxypyridoxine_model> a rdfs:Class ;
  rdfs:label "methoxypyridoxine model" ;
  rdfs:subClassOf <https://bio.scai.fraunhofer.de/ontology/epilepsy#convulsant_drug_model> .

obo:DOID_12894 a rdfs:Class ;
  rdfs:label "Sjogren's syndrome" ;
  rdfs:comment "An autoimmune hypersensitivity disease that involves attack of immune cells which destroy the exocrine glands that produce tears and saliva." ;
  rdfs:seeAlso <https://www.epilepsy.com/learn/professionals/co-existing-disorders/inflammatory-disorders> ;
  rdfs:subClassOf obo:DOID_417 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#focal_cognitive_seizure_with_conduction_dysphasia/aphasia> a rdfs:Class ;
  rdfs:label "focal cognitive seizure with conduction dysphasia/aphasia" ;
  rdfs:subClassOf <https://bio.scai.fraunhofer.de/ontology/epilepsy#focal_cognitive_seizure> .

obo:OGMS_0000083 a rdfs:Class ;
  rdfs:label "physical examination finding" ;
  rdfs:comment "TODO: Define." ;
  rdfs:subClassOf obo:OGMS_0000014 .

obo:HP_0012847 a rdfs:Class ;
  rdfs:label "Epilepsia partialis continua" ;
  rdfs:comment "Epilepsia partialis continua (also called Kojevnikov's or Kozhevnikov's epilepsia) is a type of focal motor status epilepticus characterized by repeated stereotyped simple motor manifestations such as jerks, typically of a limb or the face, recurring every few seconds or minutes for extended periods (days or years)." ;
  rdfs:subClassOf obo:HP_0011153 .

obo:UBERON_0016548 a rdfs:Class ;
  rdfs:label "central nervous system gray matter layer" ;
  rdfs:comment "A layer of of the central nervous system that is part of gray matter." ;
  rdfs:subClassOf obo:UBERON_0022303 .

obo:RS_0000637 a rdfs:Class ;
  rdfs:label "P77PMC" ;
  rdfs:subClassOf obo:RS_0000765 .

obo:NBO_0000027 a rdfs:Class ;
  rdfs:label "grooming behavior" ;
  rdfs:comment "The act of using body parts to pick at, rub and or remove material from exterior covering, e.g., fur, scales, feathers, skin [NBO:SMAC]" ;
  rdfs:subClassOf obo:NBO_0000313 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#fronto-parietal_operculum_seizure> a rdfs:Class ;
  rdfs:label "fronto-parietal operculum seizure" ;
  rdfs:subClassOf <https://bio.scai.fraunhofer.de/ontology/epilepsy#frontal_lobe_seizure> , <https://bio.scai.fraunhofer.de/ontology/epilepsy#parietal_lobe_seizure> .

obo:NBO_0000243 a rdfs:Class ;
  rdfs:label "behavioral phenotype" ;
  rdfs:comment "\"An observable characteristic of the behavior of an organism.\" [NBO:RH]" ;
  rdfs:subClassOf obo:GO_0007610 .

obo:SYMP_0019152 a rdfs:Class ;
  rdfs:label "diaphoresis" ;
  rdfs:comment "Diaphoresis is a sweat characterized as excessive sweating commonly associated with shock and other medical emergency conditions." ;
  rdfs:seeAlso <https://www.healthline.com/health/diaphoresis#sweat> ;
  rdfs:subClassOf obo:SYMP_0019175 .

obo:BFO_0000148 a rdfs:Class ;
  rdfs:label "zero-dimensional temporal region" ;
  rdfs:subClassOf obo:BFO_0000008 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#object_distortion> a rdfs:Class ;
  rdfs:label "object distortion" ;
  rdfs:subClassOf obo:HP_0000504 .

obo:HP_0011149 a rdfs:Class ;
  rdfs:label "Absence seizure with eyelid myoclonia" ;
  rdfs:comment "Absence seizures accompanied by brief, repetitive, often rhythmic, fast (4-6 Hz) myoclonic jerks of the eyelids with simultaneous upward deviation of the eyeballs and extension of the head. Seizures are typically very brief (less than 6s in duration) and multiple seizures occur on a daily basis. Mostly awareness is retained." ;
  rdfs:seeAlso <https://www.epilepsydiagnosis.org/seizure/awsf-eyelid-myoclonia-overview.html> ;
  rdfs:subClassOf <https://bio.scai.fraunhofer.de/ontology/epilepsy#generalized_non-motor_onset_seizure> .

obo:SYMP_0000254 a rdfs:Class ;
  rdfs:label "dilated pupil" ;
  rdfs:subClassOf obo:SYMP_0000417 .

obo:DOID_635 a rdfs:Class ;
  rdfs:label "acquired immunodeficiency syndrome" ;
  rdfs:comment "A Human immunodeficiency virus infectious disease that results_in reduction in the numbers of CD4-bearing helper T cells below 200 per ��L of blood or 14% of all lymphocytes thereby rendering the subject highly vulnerable to life-threatening infections and cancers, has_material_basis_in Human immunodeficiency virus 1 or has_material_basis_in Human immunodeficiency virus 2, which are transmitted_by sexual contact, transmitted_by transfer of blood, semen, vaginal fluid, pre-ejaculate, or breast milk, transmitted_by congenital method, and transmitted_by contaminated needles. Opportunistic infections are common in people with AIDS." ;
  rdfs:seeAlso <https://www.epilepsy.com/learn/professionals/co-existing-disorders/infectious-states-seizures/viral-infections/human> ;
  rdfs:subClassOf obo:DOID_526 .

obo:UBERON_0035927 a rdfs:Class ;
  rdfs:label "sulcus of parietal lobe" ;
  rdfs:subClassOf obo:UBERON_0013118 .

obo:MONDO_0005156 a rdfs:Class ;
  rdfs:label "encephalomyelitis" ;
  rdfs:comment "Inflammation of the brain and the spinal cord." ;
  rdfs:subClassOf obo:DOID_331 .

obo:MONDO_0016292 a rdfs:Class ;
  rdfs:label "nodular neuronal heterotopia" ;
  rdfs:seeAlso <http://www.case.edu/EpSO.owl#NodularHeterotopias> ;
  rdfs:subClassOf obo:DOID_936 .

obo:HP_0003552 a rdfs:Class ;
  rdfs:label "Muscle stiffness" ;
  rdfs:comment "A condition in which muscles cannot be moved quickly without accompanying pain or spasm." ;
  rdfs:seeAlso <https://www.epilepsysociety.org.uk/seizure-types#.XJsKjZgzbIU> ;
  rdfs:subClassOf obo:HP_0011804 .

obo:HP_0001507 a rdfs:Class ;
  rdfs:label "Growth abnormality" ;
  rdfs:subClassOf obo:HP_0000118 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#focal_emotional_seizure_with_anger> a rdfs:Class ;
  rdfs:label "focal emotional seizure with anger" ;
  rdfs:seeAlso <https://www.epilepsy.com/learn/challenges-epilepsy/moods-and-behavior/mood-and-behavior-101/aggression> ;
  rdfs:subClassOf obo:HP_0025613 .

obo:UBERON_0002473 a rdfs:Class ;
  rdfs:label "intercerebral commissure" ;
  rdfs:comment "A commissure that connects the two cerebral hemispheres. Examples: anterior commissure, corpus callosum." ;
  rdfs:subClassOf obo:UBERON_0019294 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#seizure_pattern> a rdfs:Class ;
  rdfs:label "seizure pattern" ;
  rdfs:seeAlso <http://www.case.edu/EpSO.owl#SeizurePattern> ;
  rdfs:subClassOf <https://bio.scai.fraunhofer.de/ontology/epilepsy#ictal_pattern> .

obo:HP_0100033 a rdfs:Class ;
  rdfs:label "Tics" ;
  rdfs:comment "Repeated, individually recognizable, intermittent movements or movement fragments that are almost always briefly suppresable and are usually associated with awareness of an urge to perform the movement." ;
  rdfs:subClassOf obo:MONDO_0017657 .

obo:OAE_0002391 a rdfs:Class ;
  rdfs:label "brain herniation AE" ;
  rdfs:comment "a brain disorder AE  that results in brain tissue, cerebrospinal fluid, and blood vessels being moved or pressed away from their usual position inside the skull." ;
  rdfs:subClassOf obo:OAE_0001551 .

obo:UBERON_0001871 a rdfs:Class ;
  rdfs:label "temporal lobe" ;
  rdfs:comment "Lower lateral part of the cerebral hemisphere. (MSH)" ;
  rdfs:subClassOf obo:UBERON_0016526 .

obo:HP_0001342 a rdfs:Class ;
  rdfs:label "Cerebral hemorrhage" ;
  rdfs:comment "Hemorrhage into the parenchyma of the brain." ;
  rdfs:seeAlso <http://www.case.edu/EpSO.owl#CerebralHemorrhage> ;
  rdfs:subClassOf obo:HP_0011025 .

obo:HP_0000716 a rdfs:Class ;
  rdfs:label "Depressivity" ;
  rdfs:comment "Frequent feelings of being down, miserable, and/or hopeless; difficulty recovering from such moods; pessimism about the future; pervasive shame; feeling of inferior self-worth; thoughts of suicide and suicidal behavior." ;
  rdfs:subClassOf obo:HP_0031466 .

obo:NCBITaxon_10116 a rdfs:Class ;
  rdfs:label "Rattus norvegicus" ;
  rdfs:subClassOf obo:NCBITaxon_9989 .

obo:IDOMAL_6000062 a rdfs:Class ;
  rdfs:label "medicinal plant disposition" ;
  rdfs:comment "The disposition of a plant or its parts to be used to cure disease or relieve pain." ;
  rdfs:subClassOf obo:BFO_0000016 .

obo:HP_0000365 a rdfs:Class ;
  rdfs:label "Hearing impairment" ;
  rdfs:comment "A decreased magnitude of the sensory perception of sound." ;
  rdfs:seeAlso <https://rarediseases.org/rare-diseases/progressive-myoclonus-epilepsy/> ;
  rdfs:subClassOf obo:HP_0000364 .

obo:HP_0011174 a rdfs:Class ;
  rdfs:label "Hyperkinetic seizures" ;
  rdfs:comment "Seizures with increase in rate of ongoing movements or inappropriately rapid performance of a movement involving predominantly proximal limb or axial muscles producing irregular sequential ballistic movements, such as pedaling, pelvic thrashing, rocking movements." ;
  rdfs:seeAlso <https://link.springer.com/referenceworkentry/10.1007%2F978-1-84882-128-6_61> ;
  rdfs:subClassOf obo:HP_0011153 .

obo:NCIT_C116487 a rdfs:Class ;
  rdfs:label "Diffusion Kurtosis Imaging" ;
  rdfs:comment "An extension of conventional diffusion tension imaging, which estimates the kurtosis of the water diffusion probability distribution function. This technique is most commonly used to study the brain." ;
  rdfs:subClassOf obo:NCIT_C64862 .

obo:NCIT_C100018 a rdfs:Class ;
  rdfs:label "Syncope with High Risk Cardiac Characteristics" ;
  rdfs:comment "A sudden loss of consciousness with loss of postural tone not related to anesthesia with high risk characteristics. High risk characteristics include non-ischemic dilated cardiomyopathy, or ischemic heart disease with significant ventricular dysfunction, hypertrophic cardiomyopathy, Brugada Syndrome, or Long QT Syndrome. (ACC)" ;
  rdfs:seeAlso <https://www.epilepsydiagnosis.org/epilepsy-imitators.html#longqt> ;
  rdfs:subClassOf obo:HP_0001279 .

obo:UBERON_0006099 a rdfs:Class ;
  rdfs:label "Brodmann (1909) area 1" ;
  rdfs:comment "." ;
  rdfs:subClassOf obo:UBERON_0013529 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#seizure_arising_superior_to_the_calcarine_fissure> a rdfs:Class ;
  rdfs:label "seizure arising superior to the calcarine fissure" ;
  rdfs:subClassOf <https://bio.scai.fraunhofer.de/ontology/epilepsy#occipital_lobe_seizure> .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#intermittent_slow_activity> a rdfs:Class ;
  rdfs:label "intermittent slow activity" ;
  rdfs:subClassOf obo:HP_0011203 .

obo:DOID_0080016 a rdfs:Class ;
  rdfs:label "spina bifida" ;
  rdfs:subClassOf obo:DOID_0080074 .

obo:NBO_0000338 a rdfs:Class ;
  rdfs:label "kinesthetic behavior" ;
  rdfs:comment "\"Movement behavior of the body or its parts.\"" ;
  rdfs:subClassOf obo:NBO_0000313 .

obo:PATO_0000927 a rdfs:Class ;
  rdfs:label "photosensitivity" ;
  rdfs:comment "A quality inhering in a bearer by virtue of the bearer's disposition to being sensitivity to the action of radiant energy." ;
  rdfs:subClassOf obo:PATO_0000085 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#unworthiness> a rdfs:Class ;
  rdfs:label "unworthiness" ;
  rdfs:seeAlso <http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2011000600009> ;
  rdfs:subClassOf obo:MFOEM_000001 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#focal_non_convulsive_status_epilepticus_with_impairment_of_consciousness> a rdfs:Class ;
  rdfs:label "focal non convulsive status epilepticus with impairment of consciousness" ;
  rdfs:subClassOf <https://bio.scai.fraunhofer.de/ontology/epilepsy#focal_non_convulsive_status_epilepticus> .

obo:HP_0002123 a rdfs:Class ;
  rdfs:label "Generalized myoclonic seizures" ;
  rdfs:comment "Seizures with sudden, brief (< 100 msec) involuntary single or multiple contraction(s) of muscles(s) or muscle groups of variable topography (axial, proximal limb, distal)." ;
  rdfs:subClassOf <https://bio.scai.fraunhofer.de/ontology/epilepsy#generalized_motor_onset_seizure> .

obo:NBO_0000683 a rdfs:Class ;
  rdfs:label "lateral temporal lobe epilepsy" ;
  rdfs:comment "\"A temporal lobe epilepsy arises in the neocortex on the outer surface of the temporal lobe of the brain.\" [wikipedia:http\\://en.wikipedia.org/wiki/Temporal_lobe_epilepsy]" ;
  rdfs:seeAlso <http://www.case.edu/EpSO.owl#LateralTemporalEpilepsy> ;
  rdfs:subClassOf obo:DOID_3328 .

obo:UBERON_0013540 a rdfs:Class ;
  rdfs:label "Brodmann (1909) area 9" ;
  rdfs:comment "." ;
  rdfs:subClassOf obo:UBERON_0013529 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#focal_autonomic_seizure_with_pupillary_dilation/constriction> a rdfs:Class ;
  rdfs:label "focal autonomic seizure with pupillary dilation/constriction" ;
  rdfs:seeAlso <https://www.epilepsydiagnosis.org/seizure/autonomic-overview.html> , <http://epilepsyontario.org/about-epilepsy/types-of-seizures/simple-partial-seizures/> ;
  rdfs:subClassOf obo:HP_0011154 .

obo:CMO_0001924 a rdfs:Class ;
  rdfs:label "blood cytokine measurement" ;
  rdfs:subClassOf obo:CMO_0000028 .

obo:DOID_1287 a rdfs:Class ;
  rdfs:label "cardiovascular system disease" ;
  rdfs:comment "A disease of anatomical entity which occurs in the blood, heart, blood vessels or the lymphatic system that passes nutrients (such as amino acids and electrolytes), gases, hormones, blood cells or lymph to and from cells in the body to help fight diseases and help stabilize body temperature and pH to maintain homeostasis." ;
  rdfs:subClassOf obo:DOID_7 .

obo:DOID_417 a rdfs:Class ;
  rdfs:label "autoimmune hypersensitivity disease" ;
  rdfs:comment "An immune system disease that is an overactive immune response of the body against substances and tissues normally present in the body resulting from an abnormal functioning of the immune system that results in the production of antibodies or T cell directed against the host tissues." ;
  rdfs:subClassOf obo:DOID_0060056 .

obo:PW_0000234 a rdfs:Class ;
  rdfs:label "innate immune response pathway" ;
  rdfs:comment "The innate immune response - a universal and ancient form of host defense against infection - is a first line of response to various pathogens and also to damaged cells. It plays a role in stimulating adaptive immunity; molecules generated during innate responses act as second signals that can impact on both the magnitude and the nature of the adaptive response." ;
  rdfs:subClassOf obo:PW_0000023 .

obo:DOID_9973 a rdfs:Class ;
  rdfs:label "substance dependence" ;
  rdfs:comment "A substance-related disorder that involves the continued use of alcohol or other drugs despite problems related to use of the substance." ;
  rdfs:subClassOf obo:DOID_303 .

obo:CMO_0000063 a rdfs:Class ;
  rdfs:label "blood electrolyte measurement" ;
  rdfs:subClassOf obo:CMO_0000023 .

obo:DOID_906 a rdfs:Class ;
  rdfs:label "peroxisomal disease" ;
  rdfs:comment "An inherited metabolic disorder that involves peroxisome malfunction." ;
  rdfs:subClassOf <https://bio.scai.fraunhofer.de/ontology/epilepsy#metabolic_etiology> .

obo:CMO_0000037 a rdfs:Class ;
  rdfs:label "hematocrit" ;
  rdfs:seeAlso <https://www.webmd.com/epilepsy/guide/epilepsy-blood-test> ;
  rdfs:subClassOf obo:CMO_0001356 .

obo:CMO_0000002 a rdfs:Class ;
  rdfs:label "heart rate" ;
  rdfs:subClassOf obo:CMO_0000670 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#asymmetry_pattern> a rdfs:Class ;
  rdfs:label "asymmetry pattern" ;
  rdfs:seeAlso <http://www.case.edu/EpSO.owl#AsymmetryPattern> ;
  rdfs:subClassOf <https://bio.scai.fraunhofer.de/ontology/epilepsy#special_pattern> .

obo:DOID_1827 a rdfs:Class ;
  rdfs:label "idiopathic generalized epilepsy" ;
  rdfs:comment "An epilepsy syndrome that is characterised by generalised seizures with no apparent cause which arise from many independent foci (multifocal epilepsies) or from epileptic circuits that involve the whole brain." ;
  rdfs:seeAlso <https://www.epilepsy.com/learn/professionals/about-epilepsy-seizures/idiopathic-generalized-epilepsies> ;
  rdfs:subClassOf <https://bio.scai.fraunhofer.de/ontology/epilepsy#epilepsy_classification> .

obo:NBO_0000687 a rdfs:Class ;
  rdfs:label "psychogenic non-epileptic seizure" ;
  rdfs:comment "\"A type of seizure of psychological origin that superficially resembles an epileptic seizure, but without the characteristic electrical discharges associated with epilepsy.\" [wikipedia:http\\://en.wikipedia.org/wiki/Psychogenic_non-epileptic_seizures]" ;
  rdfs:seeAlso <https://www.epilepsysociety.org.uk/non-epileptic-seizures#.XJhlBXduLIV> ;
  rdfs:subClassOf obo:NBO_0000686 .

obo:CMO_0002498 a rdfs:Class ;
  rdfs:label "blood enzyme measurement" ;
  rdfs:subClassOf obo:CMO_0000028 .

obo:DOID_10969 a rdfs:Class ;
  rdfs:label "hemiplegia" ;
  rdfs:comment "A central nervous system disease that is characterized by the complete paralysis of half of the body." ;
  rdfs:subClassOf obo:DOID_331 .

obo:BFO_0000003 a rdfs:Class ;
  rdfs:label "occurrent" ;
  rdfs:comment "An entity that has temporal parts and that happens, unfolds or develops through time." ;
  rdfs:subClassOf obo:BFO_0000001 .

obo:MONDO_0017201 a rdfs:Class ;
  rdfs:label "Spasmus nutans (disease)" ;
  rdfs:comment "Spasmus nutans (SN) is a rare eye disease characterized by the clinical triad of asymmetric and pendular nystagmus, head nodding, and torticollis." ;
  rdfs:subClassOf obo:NCIT_C69023 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#sleep_onset_rapid_eye_movement> a rdfs:Class ;
  rdfs:label "sleep onset rapid eye movement" ;
  rdfs:seeAlso <http://www.case.edu/EpSO.owl#SleepOnsetRapidEyeMovement> ;
  rdfs:subClassOf <https://bio.scai.fraunhofer.de/ontology/epilepsy#special_pattern> .

obo:OGMS_0000045 a rdfs:Class ;
  rdfs:label "disorder" ;
  rdfs:comment "A material entity which is clinically abnormal and part of an extended organism. Disorders are the physical basis of disease." ;
  rdfs:subClassOf obo:BFO_0000040 .

obo:MP_0001956 a rdfs:Class ;
  rdfs:label "hypopnea" ;
  rdfs:comment "breathing that is shallower and/or slower than normal" ;
  rdfs:seeAlso <http://www.case.edu/EpSO.owl#HypopneaSyndrome> ;
  rdfs:subClassOf obo:DOID_535 .

obo:MONDO_0016701 a rdfs:Class ;
  rdfs:label "oligoastrocytic tumor" ;
  rdfs:subClassOf obo:MONDO_0015917 .

obo:NCIT_C50697 a rdfs:Class ;
  rdfs:label "Phosphene Visualization" ;
  rdfs:comment "An objective visual sensation that appears with the eyes closed and in the absence of visual light." ;
  rdfs:subClassOf obo:HP_0000504 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#focal_to_bilateral_tonic_clonic_seizure> a rdfs:Class ;
  rdfs:label "focal to bilateral tonic clonic seizure" ;
  rdfs:seeAlso <https://epilepsynewengland.org/knowledge-center/types-of-seizures/focal-bilateral-tonic-clonic-seizures> , <https://www.epilepsy.com/learn/types-seizures/focal-bilateral-tonic-clonic-seizures-aka-secondarily-generalized-seizures> ;
  rdfs:subClassOf obo:HP_0007359 .

obo:UBERON_0034925 a rdfs:Class ;
  rdfs:label "anatomical collection" ;
  rdfs:comment "A collection of anatomical structures that are alike in terms of their morphology or developmental origin." ;
  rdfs:subClassOf obo:UBERON_0000465 .

obo:OAE_0000934 a rdfs:Class ;
  rdfs:label "coagulopathy AE" ;
  rdfs:comment "coagulopathy AE results in the impairment of blood to clot causing ecessive or prolonged bleeding. " ;
  rdfs:seeAlso <http://www.case.edu/EpSO.owl#CoagulopathyHemorrhage> ;
  rdfs:subClassOf obo:MONDO_0013792 .

obo:HP_0100022 a rdfs:Class ;
  rdfs:label "Abnormality of movement" ;
  rdfs:comment "An abnormality of movement with a neurological basis characterized by changes in coordination and speed of voluntary movements." ;
  rdfs:subClassOf obo:HP_0012638 .

obo:CMO_0001240 a rdfs:Class ;
  rdfs:label "cerebrospinal fluid measurement" ;
  rdfs:subClassOf obo:CMO_0001970 .

obo:DOID_3328 a rdfs:Class ;
  rdfs:label "temporal lobe epilepsy" ;
  rdfs:seeAlso <http://www.case.edu/EpSO.owl#TemporalLobeEpilepsy> ;
  rdfs:subClassOf obo:DOID_1826 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#methyl-6,7-dimethoxy-4-ethyl-beta-carboline-3-carboxylate_model> a rdfs:Class ;
  rdfs:label "methyl-6,7-dimethoxy-4-ethyl-beta-carboline-3-carboxylate model" ;
  rdfs:subClassOf <https://bio.scai.fraunhofer.de/ontology/epilepsy#beta-carboline_model> .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#experiential_sensory_seizures> a rdfs:Class ;
  rdfs:label "experiential sensory seizure" ;
  rdfs:subClassOf obo:SYMP_0000124 .

obo:HP_0025454 a rdfs:Class ;
  rdfs:label "Abnormal CSF metabolite level" ;
  rdfs:comment "Any deviation from the normal range of concentration of a metabolite in the cerebrospinal fluid." ;
  rdfs:subClassOf obo:HP_0002921 .

obo:OMIT_0026277 a rdfs:Class ;
  rdfs:label "Ketogenic Diet" ;
  rdfs:subClassOf obo:OMIT_0005305 .

obo:MONDO_0005567 a rdfs:Class ;
  rdfs:label "substance withdrawal syndrome" ;
  rdfs:comment "A substance-specific organic brain syndrome that follows the discontinuation of administration or use, or reduction in intake of an addictive substance, e.g. opioids, barbiturates and alcohol; amphetamines or similarly acting sympathomimetics; cocaine; nicotine; sedatives, hypnotics, or anxiolytics. Syndrome manifests with diverse, often painful physical and psychological symptoms, which include but not limited to intense drug craving, anxiety, depression, insomnia, nausea, perspiration, body aches, tremors, hallucinations, and convulsions." ;
  rdfs:subClassOf obo:DOID_303 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#ictal_or_post-ictal_cardiac_abnormality> a rdfs:Class ;
  rdfs:label "ictal or post-ictal cardiac abnormality" ;
  rdfs:subClassOf obo:SYMP_0000528 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#background_suppression> a rdfs:Class ;
  rdfs:label "background suppression" ;
  rdfs:seeAlso <http://www.case.edu/EpSO.owl#BackgroundSuppression> ;
  rdfs:subClassOf <https://bio.scai.fraunhofer.de/ontology/epilepsy#special_pattern> .

obo:HP_0001574 a rdfs:Class ;
  rdfs:label "Abnormality of the integument" ;
  rdfs:comment "An abnormality of the integument, which consists of the skin and the superficial fascia." ;
  rdfs:subClassOf obo:HP_0000118 .

<https://bio.scai.fraunhofer.de/ontology/epilepsyZung_self-rating_anxiety_scale> a rdfs:Class ;
  rdfs:label "Zung self-rating anxiety scale" ;
  rdfs:subClassOf obo:NCIT_C20993 .

obo:UBERON_0002021 a rdfs:Class ;
  rdfs:label "occipital lobe" ;
  rdfs:comment "Posterior part of the cerebral hemisphere (MSH)" ;
  rdfs:subClassOf obo:UBERON_0016526 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#hippocampal_epilepsy> a rdfs:Class ;
  rdfs:label "hippocampal epilepsy" ;
  rdfs:seeAlso <http://www.medlink.com/article/hippocampal_and_parahippocampal_seizures> , <http://www.case.edu/EpSO.owl#HippocampalEpilepsy> ;
  rdfs:subClassOf obo:DOID_3328 .

obo:DOID_310 a rdfs:Class ;
  rdfs:label "MERRF syndrome" ;
  rdfs:comment "OMIM mapping confirmed by DO. [SN]." ;
  rdfs:subClassOf obo:MONDO_0044970 .

obo:DOID_5113 a rdfs:Class ;
  rdfs:label "nutritional deficiency disease" ;
  rdfs:comment "A nutrition disease that is characterized by deficiency of a nutritional element, such as a vitamin, mineral, carbohydrate, protein, fat, or general energy content." ;
  rdfs:seeAlso <https://www.epilepsy.com/learn/triggers-seizures/nutritional-deficiencies> ;
  rdfs:subClassOf obo:DOID_374 .

obo:MONDO_0021248 a rdfs:Class ;
  rdfs:label "nervous system neoplasm" ;
  rdfs:comment "A neoplasm (disease) that involves the nervous system." ;
  rdfs:subClassOf obo:MONDO_0005070 .

obo:NCBITaxon_8355 a rdfs:Class ;
  rdfs:label "Xenopus laevis" ;
  rdfs:subClassOf obo:NCBITaxon_8292 .

obo:DOID_365 a rdfs:Class ;
  rdfs:label "bladder disease" ;
  rdfs:comment "A urinary system disease that is located_in the bladder." ;
  rdfs:subClassOf obo:DOID_18 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#situational_cicardian_rhythm_sleep_disorder> a rdfs:Class ;
  rdfs:label "situational cicardian rhythm sleep disorder" ;
  rdfs:seeAlso <http://www.case.edu/EpSO.owl#SituationalCicardianRhythmSleepDisorder> ;
  rdfs:subClassOf obo:DOID_535 .

obo:PW_0000754 a rdfs:Class ;
  rdfs:label "drug pathway" ;
  rdfs:comment "The pharmacokinetics and the pharmacodynamics pathway elicited by the administration of specific drugs. The systems involved in drug processing and responses are also those handling exogenous, xenobiotic compounds in the cellular detoxification pathway. The distinction between a random encounter with a foreign compound and the processing of a substance administered for treatment along with the importance of genetic variation for the individual responses to particular drugs warrant their separate consideration." ;
  rdfs:subClassOf obo:PW_0000001 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#generalized_linear_model> a rdfs:Class ;
  rdfs:label "generalized linear model" ;
  rdfs:subClassOf <https://bio.scai.fraunhofer.de/ontology/epilepsy#non-deterministic_model> .

obo:UBERON_0003993 a rdfs:Class ;
  rdfs:label "interventricular foramen of CNS" ;
  rdfs:comment "The paired channels that connect the lateral and third ventricles and allows cerebrospinal fluid produced in the lateral ventricles to flow into the third ventricles" ;
  rdfs:subClassOf obo:UBERON_0004111 .

obo:SYMP_0000719 a rdfs:Class ;
  rdfs:label "memory impairment" ;
  rdfs:subClassOf obo:SYMP_0000410 .

obo:DOID_92 a rdfs:Class ;
  rdfs:label "speech disorder" ;
  rdfs:comment "A communication disorder that involves difficulty with the act of speech production." ;
  rdfs:subClassOf obo:DOID_2033 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#pilocarpine_model> a rdfs:Class ;
  rdfs:label "pilocarpine model" ;
  rdfs:subClassOf <https://bio.scai.fraunhofer.de/ontology/epilepsy#convulsant_drug_model> .

obo:PW_0000073 a rdfs:Class ;
  rdfs:label "lysine degradation pathway" ;
  rdfs:comment "Those metabolic reactions involved in the degradation of lysine. In mammals, lysine is metabolized to acetyl-CoA. A derivative of lysine, allysine, is used in the production of elastin and collagen." ;
  rdfs:subClassOf obo:PW_0000001 .

obo:HP_0007206 a rdfs:Class ;
  rdfs:label "Hemimegalencephaly" ;
  rdfs:comment "Enlargement of all or parts of one cerebral hemisphere." ;
  rdfs:subClassOf obo:NCIT_C84834 .

obo:UBERON_0005970 a rdfs:Class ;
  rdfs:label "brain commissure" ;
  rdfs:comment "any of the nerve fiber tracts that span the longitudinal fissure between the cerebral and/or cerebellar hemispheres of the brain" ;
  rdfs:subClassOf obo:UBERON_0001020 , obo:UBERON_0007702 .

obo:MONDO_0024882 a rdfs:Class ;
  rdfs:label "secondary neoplasm" ;
  rdfs:comment "A neoplasm that arises from a pre-existing lower grade lesion, or as a result of a primary lesion that has spread to secondary sites, or due to a complication of a cancer treatment." ;
  rdfs:subClassOf obo:MONDO_0023370 .

obo:CMO_0000502 a rdfs:Class ;
  rdfs:label "blood calcium level" ;
  rdfs:seeAlso <https://www.webmd.com/epilepsy/guide/epilepsy-blood-test> ;
  rdfs:subClassOf obo:CMO_0000063 .

obo:BFO_0000018 a rdfs:Class ;
  rdfs:label "zero-dimensional spatial region" ;
  rdfs:subClassOf obo:BFO_0000006 .

obo:DOID_1766 a rdfs:Class ;
  rdfs:label "factitious disorder" ;
  rdfs:comment "A disease of mental health where symptoms are deliberately produced, feigned or exaggerated in order to falsely demonstrate the presence of an illness." ;
  rdfs:seeAlso <https://www.epilepsydiagnosis.org/epilepsy-imitators.html#fabricated> , <https://www.epilepsysociety.org.uk/non-epileptic-seizures#.XJhlBXduLIV> ;
  rdfs:subClassOf obo:NCIT_C35470 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#rushing_noise> a rdfs:Class ;
  rdfs:label "rushing noise" ;
  rdfs:subClassOf obo:NBO_0000610 .

obo:DOID_0080074 a rdfs:Class ;
  rdfs:label "neural tube defect" ;
  rdfs:subClassOf obo:DOID_0080015 .

obo:DOID_0050700 a rdfs:Class ;
  rdfs:label "cardiomyopathy" ;
  rdfs:comment "A heart disease and a myopathy that is characterized by deterioration of the function of the heart muscle." ;
  rdfs:seeAlso <https://www.epilepsy.com/learn/professionals/co-existing-disorders/cardiac-disorders> ;
  rdfs:subClassOf obo:DOID_114 .

obo:CMO_0000242 a rdfs:Class ;
  rdfs:label "waist circumference" ;
  rdfs:subClassOf obo:CMO_0000296 .

obo:HP_0000119 a rdfs:Class ;
  rdfs:label "Abnormality of the genitourinary system" ;
  rdfs:comment "The presence of any abnormality of the genitourinary system." ;
  rdfs:subClassOf obo:HP_0000118 .

obo:NBO_0000494 a rdfs:Class ;
  rdfs:label "sleep breathing disorder" ;
  rdfs:comment "\"An intrinsic sleep disorder characterised by breathing abnormalities.\" [NBO:GVG]" ;
  rdfs:subClassOf obo:NBO_0000476 .

obo:UBERON_0004167 a rdfs:Class ;
  rdfs:label "orbitofrontal cortex" ;
  rdfs:comment "The region of the cerebral cortex covering the basal surface of the frontal lobes; this region normally controls emotion and decision making" ;
  rdfs:subClassOf obo:UBERON_0015593 .

obo:HP_0002133 a rdfs:Class ;
  rdfs:label "Status epilepticus" ;
  rdfs:comment "Status epilepticus is a type of prolonged seizure. The definition is based on both the length of the seizure and the time point (t1) beyond which the seizure should be regarded as continuous seizure activity. The second time point (t2) is the time of ongoing seizure activity after which there is a risk of long-term consequences. See the comment for information on t1 and t2." ;
  rdfs:subClassOf obo:SYMP_0000124 .

obo:NBO_0000389 a rdfs:Class ;
  rdfs:label "reflexive behavior" ;
  rdfs:comment "\"Behavior related to involuntary movement in response to a stimulus.\" [NBO:GVG]" ;
  rdfs:subClassOf obo:NBO_0000388 .

obo:NBO_0000308 a rdfs:Class ;
  rdfs:label "sensation behavior" ;
  rdfs:comment "\"Cognitive perception of a sensation by any of the five senses -- vision, touch, smell, taste, and hearing.\" [NBO:GVG]" ;
  rdfs:subClassOf obo:NBO_0000607 .

obo:MONDO_0019197 a rdfs:Class ;
  rdfs:label "folinic acid-responsive seizures" ;
  rdfs:comment "Folinic acid-responsive seizures is a very rare neonatal epileptic encephalopathy disorder characterized clinically by myoclonic and clonic, or clonic seizures associated with apnea occurring several hours to 5 days after birth and responding to folinic acid." ;
  rdfs:subClassOf <https://bio.scai.fraunhofer.de/ontology/epilepsy#metabolic_etiology> .

obo:HP_0032051 a rdfs:Class ;
  rdfs:label "Focal cortical dysplasia type II" ;
  rdfs:comment "A type of focal cortical dysplasia that is characterized by disrupted cortical lamination and specific cytological abnormalities." ;
  rdfs:seeAlso <http://www.case.edu/EpSO.owl#FocalCorticalDysplasiaTypeII> ;
  rdfs:subClassOf obo:HP_0032046 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#autoregressive_model> a rdfs:Class ;
  rdfs:label "autoregressive model" ;
  rdfs:subClassOf <https://bio.scai.fraunhofer.de/ontology/epilepsy#non-deterministic_model> .

obo:HP_0011185 a rdfs:Class ;
  rdfs:label "EEG with focal epileptiform discharges" ;
  rdfs:comment "EEG discharges recorded in particular areas of a localized (focal) abnormality in cerebral electrical activity recorded along the scalp by electroencephalography (EEG)." ;
  rdfs:subClassOf obo:HP_0011182 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#paroxysmal_kinesigenic_dyskinesia> a rdfs:Class ;
  rdfs:label "paroxysmal kinesigenic dyskinesia" ;
  rdfs:subClassOf obo:MONDO_0017657 .

obo:MFOEM_000027 a rdfs:Class ;
  rdfs:label "terror" ;
  rdfs:seeAlso <https://www.epilepsy.com/connect/forums/living-epilepsy-adults/feelings-terror-seizures> ;
  rdfs:subClassOf obo:MFOEM_000026 .

obo:UBERON_0000464 a rdfs:Class ;
  rdfs:label "anatomical space" ;
  rdfs:comment "Non-material anatomical entity of three dimensions, that is generated by morphogenetic or other physiologic processes; is surrounded by one or more anatomical structures; contains one or more organism substances or anatomical structures." ;
  rdfs:subClassOf obo:UBERON_0000466 .

obo:OMIT_0013780 a rdfs:Class ;
  rdfs:label "Sleep Deprivation" ;
  rdfs:subClassOf obo:NBO_0000475 .

obo:NCIT_C103520 a rdfs:Class ;
  rdfs:label "Hospital Anxiety and Depression Scale Questionnaire" ;
  rdfs:comment "A standardized survey developed and copyrighted by A. S. Zigmond and R. P. Snaith in 1983, 1992, 1994 and published in the Acta Psychiatrica Scandinavica journal (A.S. Zigmond and R.P. Snaith. The Hospital Anxiety and Depression Scale. Acta psychiart. scand. 1983, 67:361-370) which is used to detect depression and anxiety in individuals in a hospital or medical outpatient clinic. This instrument is a self-administered questionnaire consisting of 14 items that assess how the individual has felt over the past week. Each item as 4 response options that are associated with a score of 0 to 3." ;
  rdfs:subClassOf obo:NCIT_C91105 .

obo:DOID_10273 a rdfs:Class ;
  rdfs:label "heart conduction disease" ;
  rdfs:comment "A cardiovascular system disease that involves the heart's electrical conduction system." ;
  rdfs:subClassOf obo:DOID_114 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#primitive_behavior> a rdfs:Class ;
  rdfs:label "primitive behavior" ;
  rdfs:seeAlso <https://link.springer.com/chapter/10.1385/1-59259-872-2:189> ;
  rdfs:subClassOf obo:GO_0007610 .

obo:SYMP_0000412 a rdfs:Class ;
  rdfs:label "anxiety" ;
  rdfs:comment "Anxiety is a neurological and physiological symptom characterized by a painful or apprehensive uneasiness of mind usually over an impending or anticipated ill." ;
  rdfs:subClassOf obo:SYMP_0000410 .

obo:MP_0001629 a rdfs:Class ;
  rdfs:label "abnormal heart rate" ;
  rdfs:comment "greater than or fewer than average resting heart beats per minute, usually measured by the number of times the heart ventricles contract per unit of time, usually per minute" ;
  rdfs:subClassOf obo:MP_0004085 .

obo:DOID_303 a rdfs:Class ;
  rdfs:label "substance-related disorder" ;
  rdfs:comment "A disease of mental health involving the abuse or dependence on a substance that is ingested in order to produce a high, alter one's senses, or otherwise affect functioning." ;
  rdfs:subClassOf obo:DOID_150 , obo:MONDO_0005084 .

obo:NCBITaxon_8292 a rdfs:Class ;
  rdfs:label "Amphibia" ;
  rdfs:subClassOf obo:NCBITaxon_7742 .

obo:MONDO_0007295 a rdfs:Class ;
  rdfs:label "rolandic epilepsy" ;
  rdfs:comment "Rolandic epilepsy (RE) is a focal childhood epilepsy characterized by seizures consisting of unilateral facial sensory-motor symptoms, with electroencephalogram (EEG) showing sharp biphasic waves over the rolandic region. It is an age-related epilepsy, with excellent outcome." ;
  rdfs:seeAlso <http://www.case.edu/EpSO.owl#ChildhoodRolandicEpilepsy> , <https://rarediseases.info.nih.gov/diseases/10287/benign-rolandic-epilepsy-bre> ;
  rdfs:subClassOf obo:DOID_1826 .

obo:UBERON_0002710 a rdfs:Class ;
  rdfs:label "cingulate sulcus" ;
  rdfs:comment "The cingulate sulcus is a sulcus (brain fold) on the medial wall of the cerebral cortex. The frontal and parietal lobes are separated by the cingulate sulcus from the cingulate gyrus. [WP,unvetted]." ;
  rdfs:subClassOf obo:UBERON_0008334 .

obo:DOID_10608 a rdfs:Class ;
  rdfs:label "celiac disease" ;
  rdfs:comment "An autoimmune disease of gastrointestinal tract that is caused by a reaction located_in small intestine to gliadin, a prolamin (gluten protein) found in wheat, and similar proteins found in the crops of the tribe Triticeae. The disease is associated with HLA-DQ gene. It has_symptom abdominal pain, has_symptom constipation, has_symptom diarrhea, has_symptom nausea and vomiting, and has_symptom loss of appetite." ;
  rdfs:subClassOf obo:DOID_0060031 .

obo:MONDO_0100032 a rdfs:Class ;
  rdfs:label "familial temporal lobe epilepsy syndrome" ;
  rdfs:comment "This syndrome is identified in an individual who has seizures with temporal lobe features with a family history of similar seizures. Seizures often comprise such mild symptoms that they are undiagnosed. There are no implications expected for development or learning and seizures are typically infrequent and well controlled." ;
  rdfs:subClassOf obo:MONDO_0100030 .

obo:SYMP_0000898 a rdfs:Class ;
  rdfs:label "cardiac fibrillation" ;
  rdfs:comment "An arrhythmia characterized by rapid, irregular, and unsynchronized contraction of muscle fibers within the heart." ;
  rdfs:subClassOf obo:SYMP_0000287 .

obo:DOID_5393 a rdfs:Class ;
  rdfs:label "brain angioma" ;
  rdfs:subClassOf obo:DOID_255 , obo:DOID_936 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#moan> a rdfs:Class ;
  rdfs:label "moan" ;
  rdfs:subClassOf obo:GO_0007610 .

obo:NCIT_C19148 a rdfs:Class ;
  rdfs:label "In Vivo Model" ;
  rdfs:subClassOf obo:NCIT_C17456 .

obo:NCIT_C118719 a rdfs:Class ;
  rdfs:label "Monocular Diplopia" ;
  rdfs:comment "Perception of more than one image when viewing with one eye." ;
  rdfs:subClassOf obo:HP_0000504 .

obo:UBERON_0011216 a rdfs:Class ;
  rdfs:label "organ system subdivision" ;
  rdfs:comment "A subdivision of an anatomical system." ;
  rdfs:subClassOf obo:UBERON_0010000 .

obo:HP_0032180 a rdfs:Class ;
  rdfs:label "Abnormal circulating metabolite concentration" ;
  rdfs:comment "An abnormal level of an analyte measured in the blood." ;
  rdfs:subClassOf obo:HP_0001939 .

obo:NBO_0000709 a rdfs:Class ;
  rdfs:label "drug induced seizure" ;
  rdfs:comment "\"A type of seizure induced by the administration of a drug.\" [NBO:GVG]" ;
  rdfs:seeAlso <http://www.medlink.com/article/drug-induced_seizures> ;
  rdfs:subClassOf obo:NBO_0000686 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#immune_etiology> a rdfs:Class ;
  rdfs:label "immune etiology" ;
  rdfs:subClassOf obo:NCIT_C16390 .

obo:UBERON_0002020 a rdfs:Class ;
  rdfs:label "gray matter" ;
  rdfs:comment "A nervous system structure composed primarily of nerve cell bodies (somas). May also include dendrites and the initial unmyelinated portion of axons." ;
  rdfs:subClassOf obo:UBERON_0011215 .

obo:BFO_0000140 a rdfs:Class ;
  rdfs:label "continuant fiat boundary" ;
  rdfs:comment "b is a continuant fiat boundary = Def. b is an immaterial entity that is of zero, one or two dimensions and does not include a spatial region as part. (axiom label in BFO2 Reference: [029-001])" ;
  rdfs:subClassOf obo:BFO_0000141 .

obo:UBERON_0006471 a rdfs:Class ;
  rdfs:label "Brodmann (1909) area 5" ;
  rdfs:comment "Brodmann area 5 is one of Brodmann's cytologically defined regions of the brain. It is involved in somatosensory processing and association." ;
  rdfs:subClassOf obo:UBERON_0013529 .

obo:MFOEM_000195 a rdfs:Class ;
  rdfs:label "affective process" ;
  rdfs:comment "An affective process is any process that has positive or negative valence. " ;
  rdfs:subClassOf obo:MF_0000020 .

obo:HP_0032662 a rdfs:Class ;
  rdfs:label "Focal-onset seizure evolving into bilateral convulsive status epilepticus" ;
  rdfs:comment "A type of bilateral convulsive seizure of focal onset (which could be with awareness or impaired awareness, either motor or non- motor) that is sufficiently prolonged (or repeated without recovery) to reach the threshold for status epilepticus." ;
  rdfs:subClassOf obo:HP_0032660 .

obo:DOID_654 a rdfs:Class ;
  rdfs:label "overnutrition" ;
  rdfs:comment "A nutrition disease that is characterized by an excess of a nutritional element, such as a vitamin, mineral, carbohydrate, protein, fat, or general energy content." ;
  rdfs:subClassOf obo:DOID_374 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#autonomic_status_epilepsy> a rdfs:Class ;
  rdfs:label "autonomic status epilepsy" ;
  rdfs:subClassOf <https://bio.scai.fraunhofer.de/ontology/epilepsy#focal_non_convulsive_status_epilepticus> .

obo:DOID_4890 a rdfs:Class ;
  rdfs:label "juvenile myoclonic epilepsy" ;
  rdfs:comment "A adolescence-adult electroclinical syndrome that is characterized by brief, involuntary twitching of a muscle or a group of muscles (myoclonus) early in the morning with onset between 12 and 18 years." ;
  rdfs:seeAlso <http://www.case.edu/EpSO.owl#JuvenileMyoclonicEpilepsy> ;
  rdfs:subClassOf obo:DOID_1827 , obo:MONDO_0100030 .

obo:HP_0025032 a rdfs:Class ;
  rdfs:label "Abnormality of digestive system physiology" ;
  rdfs:comment "A functional anomaly of the digestive system." ;
  rdfs:subClassOf obo:HP_0025031 .

obo:DOID_2490 a rdfs:Class ;
  rdfs:label "congenital nervous system abnormality" ;
  rdfs:seeAlso <http://www.case.edu/EpSO.owl#CongenitalNeurologicalDeficit> ;
  rdfs:subClassOf obo:DOID_0080015 .

obo:UBERON_0024151 a rdfs:Class ;
  rdfs:label "tegmentum" ;
  rdfs:comment "The ventral topographic division of the midbrain; the dorsal topographic division is the tectum. Meckel (1817; see English translation, 1832, vol. 2, p. 467) apparently introduced the term and roughly its definition here for macrodissected adult humans, except he excluded the cerebral peduncle (Tarin, 1753), a white matter tract at the base of the midbrain, which is still common today but is included here. As defined here, tegmentum refers to the whole of the midbrain (Baer, 1837) excluding the tectum but including the pretectal region (Scalia, 1972); see Swanson (2000, pp. 522, 526). Usage of this term is very complex, inconsistent, and illogical; see for example Crosby et al. (1962, pp. 221, 260, 262), Carpenter (1976, p. 367 ff.)." ;
  rdfs:subClassOf obo:UBERON_0022776 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#self-limited_familial_and_non-familial_infantile_epilepsy> a rdfs:Class ;
  rdfs:label "self-limited familial and non-familial infantile epilepsy" ;
  rdfs:subClassOf obo:MONDO_0100022 .

obo:UBERON_0002422 a rdfs:Class ;
  rdfs:label "fourth ventricle" ;
  rdfs:comment "Part of the ventricular system of the brain, forming a single large irregularly shaped cavity located on the midline of the rhombencephalon, between the medulla, pons and the isthmus ventrally and the cerebellum dorsally. It is continuous with the cerebral aqueduct anteriorally and the central canal of the spinal cord posteriorly. It communicates with the subarachnoid space through its lateral and median apertures." ;
  rdfs:subClassOf obo:UBERON_0004086 .

obo:HP_0011166 a rdfs:Class ;
  rdfs:label "Focal myoclonic seizures" ;
  rdfs:subClassOf obo:HP_0011153 .

obo:HP_0012373 a rdfs:Class ;
  rdfs:label "Abnormal eye physiology" ;
  rdfs:comment "A functional anomaly of the eye." ;
  rdfs:subClassOf obo:HP_0000478 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#tetanus_toxin_model> a rdfs:Class ;
  rdfs:label "tetanus toxin model" ;
  rdfs:subClassOf <https://bio.scai.fraunhofer.de/ontology/epilepsy#convulsant_drug_model> .

obo:UBERON_0006100 a rdfs:Class ;
  rdfs:label "Brodmann (1909) area 3" ;
  rdfs:comment "." ;
  rdfs:subClassOf obo:UBERON_0013529 .

obo:DOID_0050828 a rdfs:Class ;
  rdfs:label "artery disease" ;
  rdfs:comment "A vascular disease that is located_in an artery." ;
  rdfs:subClassOf obo:DOID_178 .

obo:DOID_9351 a rdfs:Class ;
  rdfs:label "diabetes mellitus" ;
  rdfs:comment "A glucose metabolism disease characterized  by chronic hyperglycaemia with disturbances of carbohydrate, fat and protein metabolism resulting from defects in insulin secretion, insulin action, or both." ;
  rdfs:subClassOf obo:DOID_4194 .

obo:UBERON_0000119 a rdfs:Class ;
  rdfs:label "cell layer" ;
  rdfs:comment "Portion of tissue, that consists of single layer of cells connected to each other by cell junctions. Examples: layer of glial cells; epithelium." ;
  rdfs:subClassOf obo:UBERON_0000957 .

obo:UBERON_0002721 a rdfs:Class ;
  rdfs:label "lateral sulcus" ;
  rdfs:comment "A sulcus that divides the frontal lobe and parietal lobe above from the temporal lobe below. It is in both hemispheres of the brain but is longer in the left hemisphere. The lateral sulcus is one of the earliest-developing sulci of the human brain. It first appears around the fourteenth gestational week[WP,modified]." ;
  rdfs:subClassOf obo:UBERON_0008334 .

obo:NCIT_C17429 a rdfs:Class ;
  rdfs:label "Neural Network" ;
  rdfs:comment "A computer algorithm to solve non-linear optimization problems. The algorithm was derived in analogy to the way the densely interconnected, parallel structure of the brain processes information." ;
  rdfs:subClassOf obo:NCIT_C61377 .

obo:DOID_2468 a rdfs:Class ;
  rdfs:label "psychotic disorder" ;
  rdfs:comment "A cognitive disorder that involves abnormal thinking and perceptions resulting in a disconnection with reality." ;
  rdfs:subClassOf obo:DOID_1561 .

obo:UBERON_0013118 a rdfs:Class ;
  rdfs:label "sulcus of brain" ;
  rdfs:comment "A depression or fissure in the surface of the brain. It surrounds the gyri, creating the characteristic appearance of the brain in humans and other large mammals." ;
  rdfs:subClassOf obo:UBERON_0000093 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#left_mesial_temporal_lesion> a rdfs:Class ;
  rdfs:label "left mesial temporal lesion" ;
  rdfs:seeAlso <http://www.case.edu/EpSO.owl#LeftMesialTemporalLesion> ;
  rdfs:subClassOf obo:DOID_936 .

obo:DOID_65 a rdfs:Class ;
  rdfs:label "connective tissue disease" ;
  rdfs:comment "A musculoskeletal system disease that affects tissues such as skin, tendons, and cartilage." ;
  rdfs:subClassOf obo:DOID_17 .

obo:NBO_0000748 a rdfs:Class ;
  rdfs:label "tongue movement" ;
  rdfs:comment "The act of displacing part or all of the tongue from its current position [NBO:SMAC]" ;
  rdfs:subClassOf obo:NBO_0000007 .

obo:UBERON_0003528 a rdfs:Class ;
  rdfs:label "brain gray matter" ;
  rdfs:comment "A gray matter that is part of a brain [Automatically generated definition]." ;
  rdfs:subClassOf obo:UBERON_0002020 .

obo:NCIT_C74739 a rdfs:Class ;
  rdfs:label "Glutamate Measurement" ;
  rdfs:comment "The determination of the amount of glutamate present in a sample." ;
  rdfs:subClassOf obo:OBA_0000116 .

obo:RS_0001872 a rdfs:Class ;
  rdfs:label "F344-Adms/Kyo" ;
  rdfs:subClassOf obo:RS_0000461 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#infectious_etiology> a rdfs:Class ;
  rdfs:label "infectious etiology" ;
  rdfs:subClassOf obo:NCIT_C16390 .

obo:GO_0097193 a rdfs:Class ;
  rdfs:label "intrinsic apoptotic signaling pathway" ;
  rdfs:comment "A series of molecular signals in which an intracellular signal is conveyed to trigger the apoptotic death of a cell. The pathway starts with reception of an intracellular signal (e.g. DNA damage, endoplasmic reticulum stress, oxidative stress etc.), and ends when the execution phase of apoptosis is triggered. The intrinsic apoptotic signaling pathway is crucially regulated by permeabilization of the mitochondrial outer membrane (MOMP)." ;
  rdfs:subClassOf obo:GO_0007165 .

obo:UBERON_0003027 a rdfs:Class ;
  rdfs:label "cingulate cortex" ;
  rdfs:comment "The cingulate cortex is a part of the brain situated in the medial aspect of the cortex. It is extended from the corpus callosum below to the cingulate sulcus above, at least anteriorly. [WP,unvetted]." ;
  rdfs:seeAlso <http://www.case.edu/EpSO.owl#CingulateSegment> ;
  rdfs:subClassOf obo:UBERON_0002616 .

obo:OMIT_0007063 a rdfs:Class ;
  rdfs:label "Gestures" ;
  rdfs:subClassOf obo:GO_0007610 .

obo:UBERON_0007245 a rdfs:Class ;
  rdfs:label "nuclear complex of neuraxis" ;
  rdfs:comment "Gray matter of the central nervous system which is a collection of clustered nuclei." ;
  rdfs:subClassOf obo:UBERON_0002020 .

obo:DOID_0060172 a rdfs:Class ;
  rdfs:label "juvenile absence epilepsy" ;
  rdfs:comment "An adolescence-adult electroclinical syndrome statring between the age of ten to 17 years characterized by the occurrence of typical absence seizures." ;
  rdfs:seeAlso <http://www.case.edu/EpSO.owl#JuvenileAbsenceEpilepsy> ;
  rdfs:subClassOf obo:DOID_1827 , obo:MONDO_0100030 .

obo:OMIT_0012985 a rdfs:Class ;
  rdfs:label "Rejection (Psychology)" ;
  rdfs:subClassOf obo:GO_0007610 .

obo:DOID_1927 a rdfs:Class ;
  rdfs:label "sphingolipidosis" ;
  rdfs:comment "A lipid storage disease characterized by functional deficiencies in the enzymes needed for lysosomal degradation of sphingolipid substrates." ;
  rdfs:subClassOf obo:DOID_9455 .

obo:DOID_0060039 a rdfs:Class ;
  rdfs:label "autoimmune disease of skin and connective tissue" ;
  rdfs:comment "An autoimmune hypersensitivity disease that is the abnormal functioning of the immune system that causes your immune system to produce antibodies or T cells against cells and/or tissues in the skin and connective tissue." ;
  rdfs:subClassOf obo:DOID_1575 , obo:DOID_3488 .

obo:FMA_71055 a rdfs:Class ;
  rdfs:label "Supracalcarine cortex (SCAL)" ;
  rdfs:subClassOf obo:UBERON_0000956 .

obo:HP_0003808 a rdfs:Class ;
  rdfs:label "Abnormal muscle tone" ;
  rdfs:subClassOf obo:HP_0011804 .

obo:NCIT_C84932 a rdfs:Class ;
  rdfs:label "Neurocysticercosis" ;
  rdfs:comment "A parasitic infection with tapeworms of the genus Taenia affecting the brain. It is manifested with seizures and headaches." ;
  rdfs:subClassOf <https://bio.scai.fraunhofer.de/ontology/epilepsy#infectious_etiology> .

obo:DOID_16 a rdfs:Class ;
  rdfs:label "integumentary system disease" ;
  rdfs:comment "A disease of anatomical entity that is located_in the integumentary system comprising the skin and its appendages." ;
  rdfs:subClassOf obo:DOID_7 .

obo:OMIT_0005305 a rdfs:Class ;
  rdfs:label "Diet Therapy" ;
  rdfs:subClassOf obo:NCIT_C65017 .

obo:NBO_0000608 a rdfs:Class ;
  rdfs:label "hallucination" ;
  rdfs:comment "\"Perception in the absence of a stimulus.\" [wikipedia:Hallucination]" ;
  rdfs:subClassOf obo:NCIT_C35470 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#rarely_repeated_seizure_(oligo-epilepsy)> a rdfs:Class ;
  rdfs:label "rarely repeated seizure (oligo-epilepsy)" ;
  rdfs:subClassOf <https://bio.scai.fraunhofer.de/ontology/epilepsy#seizure_not_necessarily_requiring_a_diagnosis_of_epilepsy> .

obo:HP_0010636 a rdfs:Class ;
  rdfs:label "Schizencephaly" ;
  rdfs:comment "The presence of a cleft in the cerebral cortex unilaterally or bilaterally, usually located in the frontal area." ;
  rdfs:subClassOf obo:NCIT_C84834 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#focal_emotional_seizure_with_fear/anxiety/panic> a rdfs:Class ;
  rdfs:label "focal emotional seizure with fear/anxiety/panic" ;
  rdfs:seeAlso <https://www.epilepsy.com/learn/challenges-epilepsy/moods-and-behavior/mood-and-behavior-101/anxiety> ;
  rdfs:subClassOf obo:HP_0025613 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#wicket_wave> a rdfs:Class ;
  rdfs:label "wicket wave" ;
  rdfs:seeAlso <http://www.case.edu/EpSO.owl#WicketSpike> , <https://emedicine.medscape.com/article/1140563-overview#a1> ;
  rdfs:subClassOf <https://bio.scai.fraunhofer.de/ontology/epilepsy#epileptiform_benign_variant> .

obo:NBO_0000510 a rdfs:Class ;
  rdfs:label "sleep paralysis" ;
  rdfs:comment "\"A REM parasomnia characterised by periods of inability to perform voluntary movements either when going to sleep or when waking up.\" [wikipedia:Sleep_paralysis]" ;
  rdfs:seeAlso <http://www.case.edu/EpSO.owl#SleepParalysis> ;
  rdfs:subClassOf obo:NBO_0000032 , obo:NBO_0000504 .

obo:DOID_0060033 a rdfs:Class ;
  rdfs:label "autoimmune disease of peripheral nervous system" ;
  rdfs:comment "An autoimmune disease of the nervous system that is the abnormal functioning of the immune system that causes your immune system to produce antibodies or T cells against cells and/or tissues in the peripheral nervous system." ;
  rdfs:subClassOf obo:DOID_438 , obo:DOID_574 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#zinc_model> a rdfs:Class ;
  rdfs:label "zinc model" ;
  rdfs:subClassOf <https://bio.scai.fraunhofer.de/ontology/epilepsy#convulsant_drug_model> .

obo:HP_0010850 a rdfs:Class ;
  rdfs:label "EEG with spike-wave complexes" ;
  rdfs:comment "Complexes of spikes (<70 ms) and sharp waves (70-200 ms), which are sharp transient waves that have a strong association with epilepsy, in cerebral electrical activity recorded along the scalp by electroencephalography (EEG)." ;
  rdfs:subClassOf obo:HP_0011198 .

obo:UBERON_0013539 a rdfs:Class ;
  rdfs:label "Brodmann (1909) area 8" ;
  rdfs:comment "Brodmann area 8 is one of Brodmann's cytologically defined regions of the brain. It is involved in planning complex movements." ;
  rdfs:subClassOf obo:UBERON_0013529 .

obo:MONDO_0019137 a rdfs:Class ;
  rdfs:label "non-24-hour sleep-wake syndrome" ;
  rdfs:comment "Non-24-hour sleep-wake disorder (non-24 disorder), also known as hypernychthemeral syndrome, is a circadian rhythm sleep disorder characterized by non-synchronization to a 24-hour day leading to insomnia and daytime sleepiness with sometimes severe associated manifestations." ;
  rdfs:seeAlso <http://www.case.edu/EpSO.owl#NonTwentyFourHourSleepWakeSyndrome> ;
  rdfs:subClassOf obo:MONDO_0024361 .

obo:UBERON_0006476 a rdfs:Class ;
  rdfs:label "Brodmann (1909) area 33" ;
  rdfs:comment "Brodmann area 33, also known as pregenual area 33, is a subdivision of the cytoarchitecturally defined cingulate region of cerebral cortex. It is a narrow band located in the anterior cingulate gyrus adjacent to the supracallosal gyrus in the depth of the callosal sulcus, near the genu of the corpus callosum. Cytoarchitecturally it is bounded by the ventral anterior cingulate area 24 and the supracallosal gyrus (Brodmann-1909)." ;
  rdfs:subClassOf obo:UBERON_0013529 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#frontal_intermittent_rhythmic_delta_activity> a rdfs:Class ;
  rdfs:label "frontal intermittent rhythmic delta activity" ;
  rdfs:subClassOf obo:HP_0002353 .

obo:DOID_10112 a rdfs:Class ;
  rdfs:label "sleeping sickness" ;
  rdfs:comment "A trypanosomiasis that results from infection by Trypanosoma brucei and gambiense, which is transmitted by the bite of an infected tsetse fly (Glossina spp). The symptoms include fever, headache, joint pain, itching, confusion, sensory disturbances, poor coordination and sleep disturbances." ;
  rdfs:seeAlso <http://www.case.edu/EpSO.owl#SleepingSickness> ;
  rdfs:subClassOf obo:DOID_10113 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#mesial_frontal_epilepsy> a rdfs:Class ;
  rdfs:label "mesial frontal epilepsy" ;
  rdfs:seeAlso <http://www.case.edu/EpSO.owl#MesialFrontalEpilepsy> ;
  rdfs:subClassOf obo:DOID_3331 .

obo:PW_0000024 a rdfs:Class ;
  rdfs:label "inflammatory response pathway" ;
  rdfs:comment "Inflammation is the cellular response of the innate immune system to infection or injury. Sensing of infection by pattern recognition receptors triggers signaling cascades leading to the expression of mediator genes such as the pro-inflammatory cytokines." ;
  rdfs:subClassOf obo:PW_0000001 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#right_mesial_lesion> a rdfs:Class ;
  rdfs:label "right mesial lesion" ;
  rdfs:seeAlso <http://www.case.edu/EpSO.owl#RightMesialLesion> ;
  rdfs:subClassOf obo:DOID_936 .

obo:MONDO_0002025 a rdfs:Class ;
  rdfs:label "psychiatric disorder" ;
  rdfs:comment "A disorder characterized by behavioral and/or psychological abnormalities, often accompanied by physical symptoms. The symptoms may cause clinically significant distress or impairment in social and occupational areas of functioning. Representative examples include anxiety disorders, cognitive disorders, mood disorders and schizophrenia." ;
  rdfs:subClassOf obo:DOID_150 .

obo:DOID_8461 a rdfs:Class ;
  rdfs:label "Aicardi syndrome" ;
  rdfs:comment "A syndrome that is characterized by absence or underdeveloped tissue connecting the left and right halves of the brain, infantile spasms and chorioretinal lacunae, which are defects in the light-sensitive tissue at the back of the eye." ;
  rdfs:seeAlso <https://ghr.nlm.nih.gov/condition/aicardi-syndrome> ;
  rdfs:subClassOf obo:DOID_225 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#alpha_rhythm> a rdfs:Class ;
  rdfs:label "alpha rhythm" ;
  rdfs:seeAlso <http://www.case.edu/EpSO.owl#AlphaRhythm> , <https://emedicine.medscape.com/article/1139332-overview#a1> ;
  rdfs:subClassOf <https://bio.scai.fraunhofer.de/ontology/epilepsy#normal_EEG_pattern> .

obo:MONDO_0024429 a rdfs:Class ;
  rdfs:label "Alice in wonderland syndrome" ;
  rdfs:comment "A disorienting neuropsychological condition that affects perception. People experience size distortion such as micropsia, macropsia, pelopsia, or teleopsia. Size distortion may occur of other sensory modalities." ;
  rdfs:seeAlso <http://www.case.edu/EpSO.owl#Teleopsia> ;
  rdfs:subClassOf obo:DOID_5614 .

obo:NCBITaxon_6231 a rdfs:Class ;
  rdfs:label "Nematoda" ;
  rdfs:subClassOf obo:NCBITaxon_2759 .

obo:OGMS_0000015 a rdfs:Class ;
  rdfs:label "clinical history" ;
  rdfs:comment "A series of statements representing health-relevant qualities of a patient and of a patient's family." ;
  rdfs:subClassOf obo:OGMS_0000123 .

obo:UBERON_0016526 a rdfs:Class ;
  rdfs:label "lobe of cerebral hemisphere" ;
  rdfs:comment "Subdivision of telencephalon which is one of a number of subdivisions of each hemisphere separated by both real landmarks (sulci and fissures) and arbitrary boundaries[FMA,modified]." ;
  rdfs:subClassOf obo:UBERON_0000064 .

obo:NCIT_C118507 a rdfs:Class ;
  rdfs:label "Neonatal Seizure" ;
  rdfs:comment "Abnormal hypersynchronous electrical activity in the brain of a newborn which may be associated with stereotyped movements or autonomic changes." ;
  rdfs:seeAlso <https://emedicine.medscape.com/article/1177069-overview> ;
  rdfs:subClassOf obo:SYMP_0000124 .

obo:DOID_848 a rdfs:Class ;
  rdfs:label "arthritis" ;
  rdfs:comment "A bone inflammation disease that involves a response to irritation or injury, characterized by joint pain, swelling, stiffness located_in joint and/or redness located_in skin over the joint." ;
  rdfs:subClassOf obo:DOID_3342 .

obo:OMIT_0013955 a rdfs:Class ;
  rdfs:label "Speech Therapy" ;
  rdfs:seeAlso <https://www.asdclinic.co.uk/conditions/epilepsy/speech-and-language-therapy-for-epilepsy.php> ;
  rdfs:subClassOf obo:NCIT_C15315 .

obo:DOID_963 a rdfs:Class ;
  rdfs:label "episodic ataxia" ;
  rdfs:comment "A hereditary ataxia characterized by sporadic bouts of ataxia with or without continuous muscle movement." ;
  rdfs:subClassOf obo:MONDO_0017657 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#music_tone> a rdfs:Class ;
  rdfs:label "music tone" ;
  rdfs:subClassOf obo:NBO_0000610 .

obo:MONDO_0014633 a rdfs:Class ;
  rdfs:label "myoclonic-atonic epilepsy" ;
  rdfs:subClassOf obo:MONDO_0020072 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#focal_autonomic_seizure_with_palpitation/tachycardia_/bradycardia/asystole> a rdfs:Class ;
  rdfs:label "focal autonomic seizure with palpitation/tachycardia /bradycardia/asystole" ;
  rdfs:seeAlso <https://www.epilepsydiagnosis.org/seizure/autonomic-overview.html> ;
  rdfs:subClassOf obo:HP_0011154 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#left_hemisphere_tumor_resection> a rdfs:Class ;
  rdfs:label "left hemisphere tumor resection" ;
  rdfs:seeAlso <http://www.case.edu/EpSO.owl#LeftHemisphereTumorResection> ;
  rdfs:subClassOf obo:OMIABIS_0001041 .

obo:PATO_0001913 a rdfs:Class ;
  rdfs:label "ictal" ;
  rdfs:comment "A physiological state which is characterized by periods of high-frequency high amplitude electrical activity in neuronal tissue." ;
  rdfs:subClassOf obo:PATO_0001912 .

obo:HP_0003549 a rdfs:Class ;
  rdfs:label "Abnormality of connective tissue" ;
  rdfs:comment "Any abnormality of the soft tissues, including both connective tissue (tendons, ligaments, fascia, fibrous tissues, and fat)." ;
  rdfs:subClassOf obo:HP_0000118 .

obo:MFOEM_000001 a rdfs:Class ;
  rdfs:label "emotion process" ;
  rdfs:comment "An emotion process is a complex mental process that is a synchronized aggregate of constituent mental processes including an appraisal process as part, and which gives rise to an action tendency." ;
  rdfs:subClassOf obo:MFOEM_000195 .

obo:UBERON_0002037 a rdfs:Class ;
  rdfs:label "cerebellum" ;
  rdfs:comment "Part of the metencephalon that lies in the posterior cranial fossa behind the brain stem. It is concerned with the coordination of movement[MESH]. A large dorsally projecting part of the brain concerned especially with the coordination of muscles and the maintenance of bodily equilibrium, situated between the brain stem and the back of the cerebrum , and formed in humans of two lateral lobes and a median lobe[BTO]. Brain structure derived from the anterior hindbrain, and perhaps including posterior midbrain. The cerebellum plays a role in somatic motor function, the control of muscle tone, and balance[ZFA]." ;
  rdfs:subClassOf obo:UBERON_0002616 .

obo:DOID_0060090 a rdfs:Class ;
  rdfs:label "central nervous system benign neoplasm" ;
  rdfs:comment "A central nervous system benign neoplasm that is characterized by lack of malignancy." ;
  rdfs:subClassOf obo:DOID_0060115 , obo:DOID_331 .

obo:MMO_0000434 a rdfs:Class ;
  rdfs:label "urine sodium analysis" ;
  rdfs:comment "A method which assesses the amount, proportions or properties of sodium in urine, the fluid waste product excreted by the kidneys. Sodium, the chemical element with atomic number 11 that in its ionic form has lost one electron, forming a cation with a charge of +1, is the chief cation of extracellular body fluids." ;
  rdfs:subClassOf obo:MMO_0000433 .

obo:NBO_0000057 a rdfs:Class ;
  rdfs:label "scratching" ;
  rdfs:comment "The act of dragging claws or nails over a surface [NBO:AC]" ;
  rdfs:subClassOf obo:NBO_0000027 .

obo:DOID_4737 a rdfs:Class ;
  rdfs:label "somatoform disorder" ;
  rdfs:comment "A disease of mental health that involves physical symptoms suggesting a physical illness where the biological or medical cause of the symptoms is indeterminate." ;
  rdfs:subClassOf obo:DOID_150 .

obo:BFO_0000031 a rdfs:Class ;
  rdfs:label "generically dependent continuant" ;
  rdfs:comment "b is a generically dependent continuant = Def. b is a continuant that g-depends_on one or more other entities. (axiom label in BFO2 Reference: [074-001])" ;
  rdfs:subClassOf obo:BFO_0000002 .

obo:NCIT_C15272 a rdfs:Class ;
  rdfs:label "Lobectomy" ;
  rdfs:comment "Surgical removal of a lobe of an organ." ;
  rdfs:seeAlso <http://www.chp.edu/our-services/brain/neurosurgery/epilepsy-surgery/services/lobectomy> ;
  rdfs:subClassOf obo:OMIABIS_0001041 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#invasive_subdural_grid_monitoring> a rdfs:Class ;
  rdfs:label "invasive subdural grid monitoring" ;
  rdfs:subClassOf <https://bio.scai.fraunhofer.de/ontology/epilepsy#invasive_preoperative_exploration> .

obo:DOID_0050460 a rdfs:Class ;
  rdfs:label "Wolf-Hirschhorn syndrome" ;
  rdfs:comment "A chromosomal deletion syndrome that is characterized by distinct craniofacial features, hypotonia and intellectual disability and has_material_basis_in a microdeletion of the short arm of chromosome 4." ;
  rdfs:subClassOf obo:MONDO_0019040 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#cobalt_model> a rdfs:Class ;
  rdfs:label "cobalt model" ;
  rdfs:subClassOf <https://bio.scai.fraunhofer.de/ontology/epilepsy#convulsant_drug_model> .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#delta_rhythm> a rdfs:Class ;
  rdfs:label "delta rhythm" ;
  rdfs:seeAlso <http://www.case.edu/EpSO.owl#DeltaRhythm> , <https://emedicine.medscape.com/article/1139332-overview#a1> ;
  rdfs:subClassOf <https://bio.scai.fraunhofer.de/ontology/epilepsy#normal_EEG_pattern> .

obo:HP_0001276 a rdfs:Class ;
  rdfs:label "Hypertonia" ;
  rdfs:comment "A condition in which there is increased muscle tone so that arms or legs, for example, are stiff and difficult to move." ;
  rdfs:subClassOf obo:HP_0002493 , obo:HP_0003808 .

obo:SYMP_0000183 a rdfs:Class ;
  rdfs:label "muscle symptom" ;
  rdfs:subClassOf obo:SYMP_0000891 .

obo:OMIT_0015836 a rdfs:Class ;
  rdfs:label "Yoga" ;
  rdfs:subClassOf obo:OGMS_0000112 .

obo:CMO_0000029 a rdfs:Class ;
  rdfs:label "platelet count" ;
  rdfs:seeAlso <https://www.epilepsy.com/learn/treating-seizures-and-epilepsy/seizure-and-epilepsy-medicines/blood-testing> ;
  rdfs:subClassOf obo:CMO_0000921 .

obo:NBO_0000424 a rdfs:Class ;
  rdfs:label "sleep terror" ;
  rdfs:comment "\"A NREM parasomnia characterised by abrupt awakening from sleep with behavior consistent with terror and a temporary inability to regain full consciousness.\" [NBO:GVG]" ;
  rdfs:seeAlso <http://www.case.edu/EpSO.owl#NightTerror> ;
  rdfs:subClassOf obo:NBO_0000499 .

obo:UBERON_0025096 a rdfs:Class ;
  rdfs:label "superior calcarine sulcus" ;
  rdfs:subClassOf obo:UBERON_0019303 .

obo:CMO_0001244 a rdfs:Class ;
  rdfs:label "cerebrospinal fluid sodium level" ;
  rdfs:seeAlso <https://link.springer.com/article/10.1007/BF02075764> ;
  rdfs:subClassOf obo:CMO_0001242 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#focal_sensory_seizure_with_hot-cold_sensation> a rdfs:Class ;
  rdfs:label "focal sensory seizure with hot-cold sensation" ;
  rdfs:subClassOf obo:HP_0011157 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#electroshock_stimulation_model> a rdfs:Class ;
  rdfs:label "electroshock stimulation model" ;
  rdfs:subClassOf obo:NCIT_C19021 .

obo:OMIT_0008942 a rdfs:Class ;
  rdfs:label "Laughter" ;
  rdfs:seeAlso <https://www.epilepsy.com/learn/types-seizures/gelastic-and-dacrystic-seizures> ;
  rdfs:subClassOf obo:GO_0007610 .

obo:HP_0002353 a rdfs:Class ;
  rdfs:label "EEG abnormality" ;
  rdfs:comment "Abnormality observed by electroencephalogram (EEG), which is used to record of the brain's spontaneous electrical activity from multiple electrodes placed on the scalp." ;
  rdfs:subClassOf obo:HP_0030178 .

obo:NCIT_C120333 a rdfs:Class ;
  rdfs:label "Word Pairs Delayed" ;
  rdfs:comment "A component of the Children's Memory Scale. A child is read a list of paired words and then asked to say the second word after being told the first. The list is presented three times in this fashion. After about 30 minutes the child is given the cued recall trial again." ;
  rdfs:subClassOf obo:NCIT_C20993 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#gustatory_illusion> a rdfs:Class ;
  rdfs:label "gustatory illusion" ;
  rdfs:subClassOf obo:SYMP_0000410 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#uremic_encephalopathy> a rdfs:Class ;
  rdfs:label "uremic encephalopathy" ;
  rdfs:seeAlso <https://www.epilepsy.com/learn/professionals/co-existing-disorders/renal-disorders/uremic-encephalopathy> , <https://emedicine.medscape.com/article/239191-overview> ;
  rdfs:subClassOf obo:DOID_557 .

obo:SYMP_0000417 a rdfs:Class ;
  rdfs:label "pupil symptom" ;
  rdfs:subClassOf obo:SYMP_0019163 .

obo:UBERON_0002686 a rdfs:Class ;
  rdfs:label "angular gyrus" ;
  rdfs:comment "Part of inferior parietal lobule formed by the cortex surrounding the upturned end of the superior temporal sulcus (Nolte, The Human Brain, 6th ed, 2009, pg 659)" ;
  rdfs:subClassOf obo:UBERON_0000200 .

obo:NBO_0000438 a rdfs:Class ;
  rdfs:label "snout reflex" ;
  rdfs:comment "\"A pouting or pursing of the lips that is elicited by light tapping of the closed lips near the midline.\" [wikipedia:Snout_reflex]" ;
  rdfs:subClassOf obo:NBO_0000390 .

obo:PATO_0002062 a rdfs:Class ;
  rdfs:label "physical quality of a process" ;
  rdfs:subClassOf obo:PATO_0001236 .

obo:HP_0100771 a rdfs:Class ;
  rdfs:label "Hypoperistalsis" ;
  rdfs:comment "Reduced or inadequate peristalsis, with resultant slow passage of contents through the digestive tract." ;
  rdfs:subClassOf obo:HP_0030914 .

obo:HP_0025097 a rdfs:Class ;
  rdfs:label "Eyelid myoclonus" ;
  rdfs:comment "Marked, involuntary jerking of the eyelids." ;
  rdfs:subClassOf obo:HP_0001336 .

obo:HP_0010936 a rdfs:Class ;
  rdfs:label "Abnormality of the lower urinary tract" ;
  rdfs:comment "An abnormality of the lower urinary tract." ;
  rdfs:subClassOf obo:HP_0000079 .

<https://w3id.org/linkml/Any> a rdfs:Class ;
  rdfs:comment "An unconstrained type or object" .

obo:HP_0001518 a rdfs:Class ;
  rdfs:label "Small for gestational age" ;
  rdfs:comment "Smaller than normal size according to sex and gestational age related norms, defined as a weight below the 10th percentile for the gestational age." ;
  rdfs:seeAlso <https://www.epilepsy.com/learn/about-epilepsy-basics/what-are-risk-factors> ;
  rdfs:subClassOf obo:HP_0004325 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#aluminum_encephalopathy_syndrome> a rdfs:Class ;
  rdfs:label "aluminum encephalopathy syndrome" ;
  rdfs:subClassOf obo:DOID_557 .

obo:CMO_0000227 a rdfs:Class ;
  rdfs:label "cell measurement" ;
  rdfs:subClassOf obo:CMO_0000000 .

obo:DOID_574 a rdfs:Class ;
  rdfs:label "peripheral nervous system disease" ;
  rdfs:comment "A nervous system disease that affects the peripheral nervous system." ;
  rdfs:subClassOf obo:DOID_863 .

obo:MONDO_0100021 a rdfs:Class ;
  rdfs:label "photosensitive occipital lobe epilepsy" ;
  rdfs:comment "A childhood-onset epilepsy that is characterized by the presence of visually-induced focal occipital lobe seizures. A proportion of patients with this syndrome have developmental delays and learning difficulty." ;
  rdfs:subClassOf obo:MONDO_0020072 .

obo:DOID_8534 a rdfs:Class ;
  rdfs:label "gastroesophageal reflux disease" ;
  rdfs:comment "OMIM mapping confirmed by DO. [SN]." ;
  rdfs:subClassOf obo:DOID_77 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#hypnopompic_seizure> a rdfs:Class ;
  rdfs:label "hypnopompic seizure" ;
  rdfs:seeAlso <http://www.case.edu/EpSO.owl#HypnopompicSeizure> ;
  rdfs:subClassOf <https://bio.scai.fraunhofer.de/ontology/epilepsy#special_seizure> .

obo:NCIT_C17456 a rdfs:Class ;
  rdfs:label "Experimental Model" ;
  rdfs:subClassOf obo:NCIT_C80519 .

obo:DOID_0060681 a rdfs:Class ;
  rdfs:label "autosomal dominant nocturnal frontal lobe epilepsy" ;
  rdfs:comment "A frontal lobe epilepsy that is characterized by autosomal dominant inheritance with childhood onset of clusters of brief nocturnal motor seizures with hyperkinetic or tonic manifestations." ;
  rdfs:seeAlso <http://www.case.edu/EpSO.owl#AutosomalDominantNocturnalFrontalLobeEpilepsy> ;
  rdfs:subClassOf obo:MONDO_0020072 .

obo:NBO_0000032 a rdfs:Class ;
  rdfs:label "paralysis" ;
  rdfs:comment "\"Loss of power of voluntary movement in a muscle through injury or disease of its nerve supply.\" [JAX:<new dbxref>]" ;
  rdfs:subClassOf obo:NBO_0000009 .

obo:DOID_0050338 a rdfs:Class ;
  rdfs:label "primary bacterial infectious disease" ;
  rdfs:comment "A bacterial infectious disease that results_in infection by bacteria as a result of their presence or activity within the normal, healthy host, and their intrinsic virulence is, in part, a necessary consequence of their need to reproduce and spread." ;
  rdfs:subClassOf obo:DOID_104 .

obo:OMIABIS_0001041 a rdfs:Class ;
  rdfs:label "surgical procedure" ;
  rdfs:comment "A planned process that uses operative manual and instrumental techniques on a patient to investigate and/or treat a pathological condition such as disease or injury, or to help improve bodily function or appearance." ;
  rdfs:subClassOf obo:OBI_0000011 .

obo:DOID_0050709 a rdfs:Class ;
  rdfs:label "early infantile epileptic encephalopathy" ;
  rdfs:comment "A neonatal period electroclinical syndrome that is characterized by tonic spasms and partial seizures." ;
  rdfs:subClassOf obo:MONDO_0100022 .

obo:SYMP_0000513 a rdfs:Class ;
  rdfs:label "stridor" ;
  rdfs:comment "Stridor is a respiratory system and chest symptom characterized by a harsh vibrating sound heard during respiration in cases of obstruction of the air passages." ;
  rdfs:subClassOf obo:SYMP_0000514 .

obo:HP_0002888 a rdfs:Class ;
  rdfs:label "Ependymoma" ;
  rdfs:comment "The presence of an ependymoma of the central nervous system." ;
  rdfs:seeAlso <http://www.case.edu/EpSO.owl#Ependymoma> ;
  rdfs:subClassOf obo:MONDO_0021042 .

obo:HP_0001626 a rdfs:Class ;
  rdfs:label "Abnormality of the cardiovascular system" ;
  rdfs:comment "Any abnormality of the cardiovascular system." ;
  rdfs:subClassOf obo:HP_0000118 .

obo:DOID_224 a rdfs:Class ;
  rdfs:label "transient cerebral ischemia" ;
  rdfs:comment "A brain ischemia that is characterized by ischemia of brief duration and without resultant tissue death." ;
  rdfs:subClassOf obo:DOID_2316 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#seizure_induced_by_chlorinated_hydrocarbon> a rdfs:Class ;
  rdfs:label "seizure induced by chlorinated hydrocarbon" ;
  rdfs:subClassOf <https://bio.scai.fraunhofer.de/ontology/epilepsy#toxic_cause_of_seizure> .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#status_semiology> a rdfs:Class ;
  rdfs:label "status semiology" ;
  rdfs:seeAlso <http://www.case.edu/EpSO.owl#StatusSemiology> ;
  rdfs:subClassOf <https://bio.scai.fraunhofer.de/ontology/epilepsy#ictal_pattern> .

obo:DOID_2538 a rdfs:Class ;
  rdfs:label "Landau-Kleffner syndrome" ;
  rdfs:comment "OMIM mapping confirmed by DO. [SN]." ;
  rdfs:subClassOf obo:MONDO_0020072 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#metaldehyde-induced_seizure> a rdfs:Class ;
  rdfs:label "metaldehyde-induced seizure" ;
  rdfs:subClassOf <https://bio.scai.fraunhofer.de/ontology/epilepsy#toxic_cause_of_seizure> .

obo:BFO_0000147 a rdfs:Class ;
  rdfs:label "zero-dimensional continuant fiat boundary" ;
  rdfs:subClassOf obo:BFO_0000140 .

obo:HP_0002126 a rdfs:Class ;
  rdfs:label "Polymicrogyria" ;
  rdfs:comment "Polymicrogyria is a congenital malformation of the cerebral cortex characterized by abnormal cortical layering (lamination) and an excessive number of small gyri (folds)." ;
  rdfs:subClassOf obo:NCIT_C84834 .

obo:NCIT_C16811 a rdfs:Class ;
  rdfs:label "Magnetoencephalography" ;
  rdfs:comment "The measurement of the magnetic fields produced by electrical activity in the brain, usually conducted externally, using extremely sensitive devices. The measurement of electric fields in the brain provides information about the localization of brain activity which is complementary to that provided by electroencephalography." ;
  rdfs:subClassOf obo:ERO_0001312 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#cognitive_aura> a rdfs:Class ;
  rdfs:label "cognitive aura" ;
  rdfs:subClassOf <https://bio.scai.fraunhofer.de/ontology/mental_disorder#cognitive_symptom> .

obo:MONDO_0043510 a rdfs:Class ;
  rdfs:label "brain injury" ;
  rdfs:comment "Acute and chronic (see also brain INJURIES, CHRONIC) injuries to the brain, including the cerebral hemispheres, CEREBELLUM, and brain STEM. Clinical manifestations depend on the nature of injury. Diffuse trauma to the brain is frequently associated with DIFFUSE AXONAL INJURY or COMA, POST-TRAUMATIC. Localized injuries may be associated with NEUROBEHAVIORAL MANIFESTATIONS; HEMIPARESIS, or other focal neurologic deficits." ;
  rdfs:seeAlso <https://www.epilepsy.com/learn/about-epilepsy-basics/what-are-risk-factors> ;
  rdfs:subClassOf obo:OGMS_0000102 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#fluid_percussion_injury_model> a rdfs:Class ;
  rdfs:label "fluid percussion injury model" ;
  rdfs:subClassOf <https://bio.scai.fraunhofer.de/ontology/epilepsy#posttraumatic_epilepsy_model> .

obo:RS_0000457 a rdfs:Class ;
  rdfs:label "rat strain" ;
  rdfs:subClassOf obo:NCBITaxon_10116 .

obo:NCIT_C91105 a rdfs:Class ;
  rdfs:label "Clinical or Research Assessment Questionnaire" ;
  rdfs:comment "An instrument consisting of a predetermined set of questions for a clinical or research assessment." ;
  rdfs:subClassOf obo:NCIT_C20993 .

obo:HP_0031879 a rdfs:Class ;
  rdfs:label "Abnormal eyelid physiology" ;
  rdfs:comment "Any functional abnormality of the eyelid." ;
  rdfs:subClassOf obo:HP_0032040 .

obo:NCIT_C49936 a rdfs:Class ;
  rdfs:label "Electrode Device" ;
  rdfs:comment "A conductor that is designed to make contact with part of a circuit or system." ;
  rdfs:subClassOf obo:OBI_0000968 .

obo:CMO_0000023 a rdfs:Class ;
  rdfs:label "blood chemistry measurement" ;
  rdfs:seeAlso <https://www.webmd.com/epilepsy/guide/epilepsy-blood-test> ;
  rdfs:subClassOf obo:CMO_0000035 .

obo:MONDO_0000456 a rdfs:Class ;
  rdfs:label "cerebral creatine deficiency syndrome" ;
  rdfs:comment "Creatine deficiency syndrome (CDS) comprises a group of inborn errors of creatine metabolism, characterized by a global developmental delay, intellectual disability and associated neurological (seizures, movement disorders, myopathy) and behavioral manifestions. CDS includes two creatine biosynthesis disorders; guanidinoacetate methyltransferase deficiency and L- Arginine: glycine amidinotransferase deficiency, as well as X-linked creatine transporter deficiency." ;
  rdfs:subClassOf <https://bio.scai.fraunhofer.de/ontology/epilepsy#metabolic_etiology> .

obo:HP_0032666 a rdfs:Class ;
  rdfs:label "Hyperkinetic status epilepticus" ;
  rdfs:comment "Status epilepticus characterized by continuous hyperkinetic proximal limb or axial muscles producing irregular sequential ballistic movements such as pedaling pelvic thrusting, thrashing, or rocking movements." ;
  rdfs:subClassOf obo:HP_0032658 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#rubbing> a rdfs:Class ;
  rdfs:label "rubbing" ;
  rdfs:subClassOf obo:GO_0007610 .

obo:BFO_0000144 a rdfs:Class ;
  rdfs:label "process profile" ;
  rdfs:comment "b is a process_profile =Def. there is some process c such that b process_profile_of c (axiom label in BFO2 Reference: [093-002])" ;
  rdfs:subClassOf obo:BFO_0000015 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#selective_amygdalohippocampectomy> a rdfs:Class ;
  rdfs:label "selective amygdalohippocampectomy" ;
  rdfs:subClassOf obo:OMIABIS_0001041 .

obo:UBERON_0034944 a rdfs:Class ;
  rdfs:label "zone of organ" ;
  rdfs:subClassOf obo:UBERON_0000064 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#interictal_behavior_disorder> a rdfs:Class ;
  rdfs:label "interictal behavior disorder" ;
  rdfs:subClassOf obo:SYMP_0019182 .

obo:MONDO_0043327 a rdfs:Class ;
  rdfs:label "cerebrospinal fluid leak" ;
  rdfs:comment "Discharge of cerebrospinal fluid through a hole through the skull bone most commonly draining from the nose (CEREBROSPINAL FLUID RHINORRHEA) or the ear (CEREBROSPINAL FLUID OTORRHEA)." ;
  rdfs:subClassOf obo:DOID_331 .

obo:SYMP_0000406 a rdfs:Class ;
  rdfs:label "bruise" ;
  rdfs:comment "Bruise is a skin and integumentary tissue symptom characterized as an injury transmitted through unbroken skin to underlying tissue causing rupture of small blood vessels and escape of blood into the tissue with resulting discoloration." ;
  rdfs:seeAlso <https://www.epilepsy.com/learn/seizure-first-aid-and-safety/staying-safe/types-injuries> ;
  rdfs:subClassOf obo:SYMP_0000488 .

obo:DOID_2978 a rdfs:Class ;
  rdfs:label "carbohydrate metabolic disorder" ;
  rdfs:comment "An inherited metabolic disorder that affect the catabolism and anabolism of carbohydrates." ;
  rdfs:subClassOf obo:DOID_655 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#parietal_lobe_epilepsy> a rdfs:Class ;
  rdfs:label "parietal lobe epilepsy" ;
  rdfs:seeAlso <http://www.case.edu/EpSO.owl#ParietalLobeEpilepsy> ;
  rdfs:subClassOf <https://bio.scai.fraunhofer.de/ontology/epilepsy#simple_focal_seizure> .

obo:HP_0032056 a rdfs:Class ;
  rdfs:label "Focal cortical dysplasia type IIIb" ;
  rdfs:comment "A subtype of focal cortical dysplasia type III that is characterized by altered architectural (cortical dyslamination, hypoplasia without six-layered structure) and/or cytoarchitectural composition (hypertrophic neurons) of the neocortex, which occur adjacent to glial or glioneuronal tumor." ;
  rdfs:seeAlso <http://www.case.edu/EpSO.owl#FocalCorticalDysplasiaTypeIIIB> ;
  rdfs:subClassOf obo:HP_0032054 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#focal_motor_seizure_with_version> a rdfs:Class ;
  rdfs:label "focal motor seizure with version" ;
  rdfs:subClassOf obo:HP_0011153 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#focal_cognitive_seizure_with_auditory_agnosia> a rdfs:Class ;
  rdfs:label "focal cognitive seizure with auditory agnosia" ;
  rdfs:subClassOf <https://bio.scai.fraunhofer.de/ontology/epilepsy#focal_cognitive_seizure> .

obo:DOID_480 a rdfs:Class ;
  rdfs:label "movement disease" ;
  rdfs:comment "A brain disease that is characterized by a clinical syndrome of either hyperkinetic movement or hyperkinetic movement unrelated to weakness or spasticity." ;
  rdfs:subClassOf obo:DOID_936 .

obo:ERO_0001330 a rdfs:Class ;
  rdfs:label "neuropsychological testing" ;
  rdfs:comment "A physiological assay that utilizes systematic administration of defined procedures to measure specific psychological functions known to be linked to particular brain structures or pathways in humans." ;
  rdfs:subClassOf obo:ERO_0001292 .

obo:UBERON_0000073 a rdfs:Class ;
  rdfs:label "regional part of nervous system" ;
  rdfs:comment "Any part or collection of parts of the central or peripheral nervous system. Parts may span both CNS and PNS." ;
  rdfs:subClassOf obo:UBERON_0000481 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#multiple_sleep_latency_test> a rdfs:Class ;
  rdfs:label "multiple sleep latency test" ;
  rdfs:subClassOf obo:OGMS_0000112 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#frontopolar_cortex_seizure> a rdfs:Class ;
  rdfs:label "frontopolar cortex seizure" ;
  rdfs:subClassOf <https://bio.scai.fraunhofer.de/ontology/epilepsy#frontal_lobe_seizure> .

obo:DOID_1561 a rdfs:Class ;
  rdfs:label "cognitive disorder" ;
  rdfs:comment "A disease of mental health that affects cognitive functions including memory processing, perception and problem solving." ;
  rdfs:subClassOf obo:DOID_150 .

obo:SYMP_0000410 a rdfs:Class ;
  rdfs:label "neurological and physiological symptom" ;
  rdfs:subClassOf obo:SYMP_0000462 .

obo:NCIT_C74838 a rdfs:Class ;
  rdfs:label "Acetylcholine Measurement" ;
  rdfs:comment "The determination of the amount of acetylcholine hormone present in a sample." ;
  rdfs:subClassOf obo:NCIT_C74742 , obo:OBA_0000116 .

obo:UBERON_0002913 a rdfs:Class ;
  rdfs:label "intraparietal sulcus" ;
  rdfs:comment "The intraparietal sulcus (IPS) is located on the lateral surface of the parietal lobe, and consists of an oblique and a horizontal portion. The IPS contains a series of functionally distinct subregions that have been intensively investigated using both single cell neurophysiology in primates and human functional neuroimaging. Its principal functions are related to perceptual-motor coordination (for directing eye movements and reaching) and visual attention. The IPS is also thought to play a role in other functions, including processing symbolic numerical information, visuospatial working memory and interpreting the intent of others. [WP,unvetted]." ;
  rdfs:seeAlso <https://link.springer.com/article/10.1186/s42494-019-0005-7> ;
  rdfs:subClassOf obo:UBERON_0035927 .

<https://bio.scai.fraunhofer.de/ontology/0000507> a rdfs:Class ;
  rdfs:label "brain functional connectivity network" ;
  rdfs:subClassOf obo:NCIT_C17429 .

obo:UBERON_0002581 a rdfs:Class ;
  rdfs:label "postcentral gyrus" ;
  rdfs:comment "Component of the parietal lobe. The appearance and disappearance of the central sulcus were the rostral and caudal boundaries of the postcentral gyrus respectively. The medial and lateral boundaries were the lateral bank of the precentral gyrus and the lateral fissure and/or the medial bank of the superior parietal gyrus respectively (Christine Fennema-Notestine)." ;
  rdfs:subClassOf obo:UBERON_0000200 .

obo:DOID_0060043 a rdfs:Class ;
  rdfs:label "sexual disorder" ;
  rdfs:comment "A disease of mental health that involves the impairment in normal sexual functioning." ;
  rdfs:subClassOf obo:DOID_150 .

obo:HP_0004323 a rdfs:Class ;
  rdfs:label "Abnormality of body weight" ;
  rdfs:comment "An abnormal increase or decrease of weight or an abnormal distribution of mass in the body." ;
  rdfs:subClassOf obo:HP_0001507 .

obo:DOID_93 a rdfs:Class ;
  rdfs:label "language disorder" ;
  rdfs:comment "A communication disorder that involves the processing of linguistic information." ;
  rdfs:subClassOf obo:DOID_2033 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#scenery_hallucination> a rdfs:Class ;
  rdfs:label "scenery hallucination" ;
  rdfs:subClassOf obo:NBO_0000609 .

obo:PATO_0002131 a rdfs:Class ;
  rdfs:label "abduction" ;
  rdfs:comment "A displaced angular placement quality inhering in a body part by virtue of the bearer's movement away from the medial plane of the body." ;
  rdfs:subClassOf obo:PATO_0002168 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#picrotoxin_model> a rdfs:Class ;
  rdfs:label "picrotoxin model" ;
  rdfs:subClassOf <https://bio.scai.fraunhofer.de/ontology/epilepsy#convulsant_drug_model> .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#infantile_behavior> a rdfs:Class ;
  rdfs:label "infantile behavior" ;
  rdfs:subClassOf obo:SYMP_0019182 .

obo:DOID_4090 a rdfs:Class ;
  rdfs:label "agnosia" ;
  rdfs:comment "A communication disorder that is a loss of ability to recognize objects, persons, sounds, shapes, or smells while the specific sense is not defective nor is there any significant memory loss." ;
  rdfs:subClassOf obo:DOID_2033 .

obo:NCBITaxon_40674 a rdfs:Class ;
  rdfs:label "Mammalia" ;
  rdfs:subClassOf obo:NCBITaxon_7742 .

obo:UBERON_0006096 a rdfs:Class ;
  rdfs:label "posterior transverse temporal area 42" ;
  rdfs:comment "A subdivision of the cytoarchitecturally defined temporal region of cerebral cortex. It is located in the bank of the lateral sulcus on the dorsal surface of the temporal lobe. Cytoarchitecturally it is bounded medially by the anterior transverse temporal area 41(H) and laterally by the superior temporal area 22 (Brodmann-1909). Adapted from Brain Info" ;
  rdfs:subClassOf obo:UBERON_0013529 .

obo:MP_0013403 a rdfs:Class ;
  rdfs:label "abnormal circulating lactate level" ;
  rdfs:comment "any anomaly of the amount of lactate in the blood which is produced from pyruvate by lactate dehydrogenase" ;
  rdfs:subClassOf obo:MP_0009642 .

obo:DOID_2033 a rdfs:Class ;
  rdfs:label "communication disorder" ;
  rdfs:comment "A specific developmental disorder that involves specific developmental disorders of speech and language." ;
  rdfs:subClassOf obo:DOID_0060038 .

obo:NCIT_C73501 a rdfs:Class ;
  rdfs:label "Perinatal Brain Injury" ;
  rdfs:comment "Injury to the brain of a newborn infant occurring around the time of birth." ;
  rdfs:seeAlso <https://www.epilepsy.com/learn/about-epilepsy-basics/what-are-risk-factors> ;
  rdfs:subClassOf obo:MONDO_0043510 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#unknown_epilepsy> a rdfs:Class ;
  rdfs:label "unknown epilepsy" ;
  rdfs:subClassOf <https://bio.scai.fraunhofer.de/ontology/epilepsy#epilepsy_classification> .

obo:OBI_0001865 a rdfs:Class ;
  rdfs:label "assay array" ;
  rdfs:comment "A device made to be used in an analyte assay for immobilization of substances that bind the analyte at regular spatial positions on a surface." ;
  rdfs:subClassOf obo:OBI_0000968 .

obo:DOID_0060319 a rdfs:Class ;
  rdfs:label "cardiac arrest" ;
  rdfs:comment "A congestive heart failure characterized by a sudden stop in effective blood circulation due to the failure of the heart to contract effectively or at all." ;
  rdfs:seeAlso <https://www.epilepsy.com/learn/professionals/co-existing-disorders/cardiac-disorders> ;
  rdfs:subClassOf obo:DOID_6000 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#congenital_stroke> a rdfs:Class ;
  rdfs:label "congenital stroke" ;
  rdfs:subClassOf obo:SYMP_0000734 .

obo:OGMS_0000102 a rdfs:Class ;
  rdfs:label "injury" ;
  rdfs:comment "A disorder that involves some structural damage that is immediately caused by a catastrophic external force." ;
  rdfs:seeAlso <https://www.epilepsy.com/learn/about-epilepsy-basics/what-are-risk-factors> ;
  rdfs:subClassOf obo:OGMS_0000045 .

obo:MONDO_0015723 a rdfs:Class ;
  rdfs:label "trisomy 12p" ;
  rdfs:comment "Trisomy 12p is an extremely rare chromosomal disorder (over 30 cases reported worldwide) characterized by craniofacial malformations (round face, prominent cheeks, high bulging forehead, broad and flat nasal bridge, short nose with anteverted nostrils, long philtrum, prominent and everted lower lip, low-set ears, abnormally folded helix, protuberant antihelix), postnatal growth retardation, mental and psychomotor retardation, generalized hypotonia, abnormally short wide hands and/or other abnormalities." ;
  rdfs:subClassOf obo:MONDO_0019040 .

obo:UBERON_0006093 a rdfs:Class ;
  rdfs:label "precuneus cortex" ;
  rdfs:comment "Component of the pareital lobe. The rostral boundary was the posterior extent of the paracentral lobule whereas the caudal boundary was the lingual gyrus. The medial and lateral boundaries were the parieto-occipital fissure and the superior parietal gyrus respectively (Christine Fennema-Notestine)." ;
  rdfs:subClassOf obo:UBERON_0000200 .

obo:IAO_0000027 a rdfs:Class ;
  rdfs:label "data item" ;
  rdfs:comment "a data item is an information content entity that is intended to be a truthful statement about something (modulo, e.g., measurement precision or other systematic errors) and is constructed/acquired by a method which reliably tends to produce (approximately) truthful statements." ;
  rdfs:subClassOf obo:IAO_0000030 .

obo:NBO_0000610 a rdfs:Class ;
  rdfs:label "auditory hallucination" ;
  rdfs:comment "\"A form of hallucination that involves perceiving sounds without auditory stimulus.\" [wikipedia:Auditory_hallucination]" ;
  rdfs:seeAlso <https://emedicine.medscape.com/article/1184509-clinical> ;
  rdfs:subClassOf obo:NBO_0000308 .

obo:HP_0010818 a rdfs:Class ;
  rdfs:label "Generalized tonic seizures" ;
  rdfs:comment "Generalized seizures with sustained increase in muscle contraction lasting a few seconds to minutes." ;
  rdfs:subClassOf <https://bio.scai.fraunhofer.de/ontology/epilepsy#generalized_motor_onset_seizure> .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#Atkins_diet> a rdfs:Class ;
  rdfs:label "Atkins diet" ;
  rdfs:seeAlso <http://purl.bioontology.org/ontology/SNOMEDCT/407667003> ;
  rdfs:subClassOf obo:OMIT_0005305 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#secondary_sensory_area_(parietal_upper_bank_of_the_sylvian_fissure)_seizure> a rdfs:Class ;
  rdfs:label "secondary sensory area (parietal upper bank of the sylvian fissure) seizure" ;
  rdfs:subClassOf <https://bio.scai.fraunhofer.de/ontology/epilepsy#parietal_lobe_seizure> .

<http://www.ebi.ac.uk/efo/EFO_0004346> a rdfs:Class ;
  rdfs:label "neuroimaging measurement" ;
  rdfs:comment "Non-invasive methods of visualizing and measuring the CENTRAL NERVOUS SYSTEM, especially the brain, by various imaging modalities e.g. CT scan" ;
  rdfs:subClassOf obo:CMO_0000000 .

obo:NCIT_C102122 a rdfs:Class ;
  rdfs:label "Short Form 36 Health Survey Standard, US Version 2.0 Questionnaire" ;
  rdfs:comment "A standardized, multipurpose, general health survey developed by John E. Ware and copyrighted by Quality Metric Inc. and the Medical Outcomes Trust in 1996 and 2000 which is used to assess the patient's functional health and overall well-being. This second version contains 36 questions that refer to the patient's symptoms or status within the past four weeks and can be completed by the patient. For each question the patient must choose from five different responses." ;
  rdfs:subClassOf obo:NCIT_C91105 .

obo:OGMS_0000061 a rdfs:Class ;
  rdfs:label "pathological bodily process" ;
  rdfs:comment "A bodily process that is clinically abnormal." ;
  rdfs:subClassOf obo:OGMS_0000060 .

obo:MONDO_0100027 a rdfs:Class ;
  rdfs:label "febrile seizures plus, genetic epilepsy with febrile seizures plus" ;
  rdfs:comment "These epilepsy syndromes are characterized by the presence of febrile seizures in an individual that may continue past the usual age where these are expected to resolve and/or be accompanied by afebrile seizures that may be generalized seizures (tonic-clonic, atonic, myoclonic, myoclonic-atonic or absence) or focal seizures. Febrile seizures plus and genetic epilepsy with febrile seizures plus are distinguished on the basis of family history. A number of dominantly inherited genes have been linked to these syndromes, with implications for specific genetic counseling, due to the variable severity of the resulting epilepsy in different family members." ;
  rdfs:subClassOf obo:MONDO_0100022 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#triphasic_wave> a rdfs:Class ;
  rdfs:label "triphasic wave" ;
  rdfs:seeAlso <http://www.case.edu/EpSO.owl#TriphasicWave> ;
  rdfs:subClassOf <https://bio.scai.fraunhofer.de/ontology/epilepsy#special_pattern> .

obo:MONDO_0017657 a rdfs:Class ;
  rdfs:label "rare paroxysmal movement disorder" ;
  rdfs:seeAlso <https://www.epilepsydiagnosis.org/epilepsy-imitators.html#paroxysmal> , <https://github.com/monarch-initiative/mondo/issues/254> ;
  rdfs:subClassOf <https://bio.scai.fraunhofer.de/ontology/epilepsy#epilepsy_imitator> .

obo:HP_0002172 a rdfs:Class ;
  rdfs:label "Postural instability" ;
  rdfs:comment "A tendency to fall or the inability to keep oneself from falling; imbalance. The retropulsion test is widely regarded as the gold standard to evaluate postural instability, Use of the retropulsion test includes a rapid balance perturbation in the backward direction, and the number of balance correcting steps (or total absence thereof) is used to rate the degree of postural instability. Healthy subjects correct such perturbations with either one or two large steps, or without taking any steps, hinging rapidly at the hips while swinging the arms forward as a counterweight. In patients with balance impairment, balance correcting steps are often too small, forcing patients to take more than two steps. Taking three or more steps is generally considered to be abnormal, and taking more than five steps is regarded as being clearly abnormal. Markedly affected patients continue to step backward without ever regaining their balance and must be caught by the examiner (this would be called true retropulsion). Even more severely affected patients fail to correct entirely, and fall backward like a pushed toy soldier, without taking any corrective steps." ;
  rdfs:seeAlso <https://www.epilepsy.com/learn/types-seizures/atonic-seizures> ;
  rdfs:subClassOf obo:HP_0100022 .

obo:BFO_0000024 a rdfs:Class ;
  rdfs:label "fiat object part" ;
  rdfs:subClassOf obo:BFO_0000040 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#posttraumatic_epilepsy_model> a rdfs:Class ;
  rdfs:label "posttraumatic epilepsy model" ;
  rdfs:subClassOf obo:NCIT_C19021 .

obo:DOID_437 a rdfs:Class ;
  rdfs:label "myasthenia gravis" ;
  rdfs:comment "An autoimmune disease of the nervous system that has_material_basis_in antibodies to acetylcholine receptors at the neuromuscular junction, has_symptom ptosis, has_symptom diplopia, has_symptom dysphagia, has_symptom dysarthria, has_symptom muscle weakness and has_symptom dyspnea." ;
  rdfs:subClassOf obo:DOID_438 .

obo:DOID_0060158 a rdfs:Class ;
  rdfs:label "acquired metabolic disease" ;
  rdfs:comment "A disease of metabolism that has _material_basis_in enzyme deficiency or accumulation of enzymes or toxins which interfere with normal function due to an endocrine organ disease, organ malfunction, inadequate intake, dietary deficiency, or malabsorption." ;
  rdfs:subClassOf obo:DOID_0014667 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#anteromesial_temporal_lobectomy> a rdfs:Class ;
  rdfs:label "anteromesial temporal lobectomy" ;
  rdfs:subClassOf obo:OMIABIS_0001041 .

obo:CMO_0001970 a rdfs:Class ;
  rdfs:label "central nervous system measurement" ;
  rdfs:subClassOf obo:CMO_0001232 .

obo:HP_0000924 a rdfs:Class ;
  rdfs:label "Abnormality of the skeletal system" ;
  rdfs:comment "An abnormality of the skeletal system." ;
  rdfs:subClassOf obo:HP_0000118 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#eye_rotation> a rdfs:Class ;
  rdfs:label "eye rotation" ;
  rdfs:subClassOf obo:HP_0000496 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#theta_activity> a rdfs:Class ;
  rdfs:label "theta activity" ;
  rdfs:seeAlso <http://www.case.edu/EpSO.owl#ThetaActivity> , <https://emedicine.medscape.com/article/1139332-overview#a1> ;
  rdfs:subClassOf <https://bio.scai.fraunhofer.de/ontology/epilepsy#normal_EEG_pattern> .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#positive_occipital_sharp_transients_of_sleep> a rdfs:Class ;
  rdfs:label "positive occipital sharp transients of sleep" ;
  rdfs:seeAlso <https://emedicine.medscape.com/article/1139332-overview#a1> ;
  rdfs:subClassOf <https://bio.scai.fraunhofer.de/ontology/epilepsy#normal_EEG_pattern> .

obo:MONDO_0005084 a rdfs:Class ;
  rdfs:label "mental disorder" ;
  rdfs:comment "A disease that has its basis in the disruption of mental process." ;
  rdfs:subClassOf obo:MONDO_0002025 .

obo:DOID_0060178 a rdfs:Class ;
  rdfs:label "familial hemiplegic migraine" ;
  rdfs:comment "A migraine with aura that is characterized by temporary numbness or weakness, often affecting one side of the body (hemiparesis). Additional features of an aura can include difficulty with speech, confusion, and drowsiness." ;
  rdfs:subClassOf <https://bio.scai.fraunhofer.de/ontology/epilepsy#migraine_associated_disorder> .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#voltage-gated_potassium_channel_antibody> a rdfs:Class ;
  rdfs:label "voltage-gated potassium channel antibody" ;
  rdfs:subClassOf obo:MONDO_0100029 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#epilepsy_with_general_tonic_clonic_seizure_on_awakening> a rdfs:Class ;
  rdfs:label "epilepsy with general tonic clonic seizure on awakening" ;
  rdfs:seeAlso <https://www.epilepsy.com/learn/types-epilepsy-syndromes/epilepsy-generalized-tonic-clonic-seizures-alone> , <http://www.case.edu/EpSO.owl#EpilepsyWithGeneralTonicClonicSeizureOnAwakening> ;
  rdfs:subClassOf obo:DOID_1826 .

obo:OGMS_0000090 a rdfs:Class ;
  rdfs:label "treatment" ;
  rdfs:comment "A planned process whose completion is hypothesized by a health care provider to eliminate, prevent, or alleviate the signs and symptoms of a disorder or pathological process" ;
  rdfs:subClassOf obo:OBI_0000011 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#auditory_illusion> a rdfs:Class ;
  rdfs:label "auditory illusion" ;
  rdfs:subClassOf obo:SYMP_0000410 .

obo:SYMP_0000428 a rdfs:Class ;
  rdfs:label "hypoventilation" ;
  rdfs:comment "Hypoventilation is a respiratory abnormality characterized by a deficient ventilation of the lungs that results in reduction in the oxygen content or increase in the carbon dioxide content of the blood or both." ;
  rdfs:subClassOf obo:SYMP_0000598 .

obo:DOID_8927 a rdfs:Class ;
  rdfs:label "learning disability" ;
  rdfs:comment "A specific developmental disorder that involves difficulty in scholastic skills such as reading, writing, spelling, reasoning, recalling and/or organizing information resulting from the brain's inability to receive and process information." ;
  rdfs:subClassOf obo:DOID_0060038 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#orbito_frontal_epilepsy> a rdfs:Class ;
  rdfs:label "orbito frontal epilepsy" ;
  rdfs:seeAlso <http://www.case.edu/EpSO.owl#OrbitoFrontalEpilepsy> , <http://www.case.edu/EpSO.owl#HypermotorSeizure> ;
  rdfs:subClassOf obo:DOID_3331 .

obo:UBERON_0000062 a rdfs:Class ;
  rdfs:label "organ" ;
  rdfs:comment "Anatomical structure that performs a specific function or group of functions [WP]." ;
  rdfs:subClassOf obo:UBERON_0010000 .

obo:NBO_0000013 a rdfs:Class ;
  rdfs:label "locomotory behavior" ;
  rdfs:comment "Movement from place to place of an organism.\" [GO:0007626]" ;
  rdfs:subClassOf obo:NBO_0000002 .

obo:DOID_50 a rdfs:Class ;
  rdfs:label "thyroid gland disease" ;
  rdfs:comment "An endocrine system disease that is located_in the thyroid." ;
  rdfs:subClassOf obo:DOID_28 .

obo:HP_0002444 a rdfs:Class ;
  rdfs:label "Hypothalamic hamartoma" ;
  rdfs:comment "The presence of a hamartoma of the hypothalamus." ;
  rdfs:seeAlso <http://www.case.edu/EpSO.owl#Hamartoma> , <http://www.case.edu/EpSO.owl#HypothalamicHamartoma> ;
  rdfs:subClassOf obo:NCIT_C84834 .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#generalized_non-motor_onset_seizure> a rdfs:Class ;
  rdfs:label "generalized non-motor onset seizure" ;
  rdfs:seeAlso <https://www.epilepsydiagnosis.org/seizure/generalized-seizure-groupoverview.html> ;
  rdfs:subClassOf obo:HP_0002197 .

obo:DOID_178 a rdfs:Class ;
  rdfs:label "vascular disease" ;
  rdfs:comment "A cardiovascular system disease that primarily affects the blood vessels which includes the arteries, veins and capillaries that carry blood to and from the heart." ;
  rdfs:subClassOf obo:DOID_1287 .

obo:HP_0032673 a rdfs:Class ;
  rdfs:label "Focal non-convulsive status epilepticus without coma" ;
  rdfs:comment "Focal non-convulsive status epilepticus without coma is a type of status epilepticus without prominent motor signs, which is electrographically focal. It is a prolonged focal non-motor seizure." ;
  rdfs:subClassOf <https://bio.scai.fraunhofer.de/ontology/epilepsy#focal_non_convulsive_status_epilepticus> .

obo:BFO_0000179 a rdf:Property ;
  rdfs:label "BFO OWL specification label" ;
  rdfs:comment "Relates an entity in the ontology to the name of the variable that is used to represent it in the code that generates the BFO OWL file from the lispy specification." ;
  rdfs:range xsd:string .

obo:BFO_0000180 a rdf:Property ;
  rdfs:label "BFO CLIF specification label" ;
  rdfs:comment "Relates an entity in the ontology to the term that is used to represent it in the the CLIF specification of BFO2" ;
  rdfs:range xsd:string .

obo:IAO_0000111 a rdf:Property ;
  rdfs:label "编辑首选术语" ;
  rdfs:comment "对于一类或属性的简洁的、有意义的、与人类友好的名称由本体开发商首选。 （美国英语）" ;
  rdfs:range xsd:string .

obo:IAO_0000112 a rdf:Property ;
  rdfs:label "example of usage" ;
  rdfs:comment "A phrase describing how a class name should be used. May also include other kinds of examples that facilitate immediate understanding of a class semantics, such as widely known prototypical subclasses or instances of the class. Although essential for high level terms, examples for low level terms (e.g., Affymetrix HU133 array) are not" ;
  rdfs:range xsd:string .

obo:IAO_0000114 a rdf:Property ;
  rdfs:label "has curation status" ;
  rdfs:range xsd:string .

obo:IAO_0000115 a rdf:Property ;
  rdfs:label "定义" ;
  rdfs:comment "The official OBI definition, explaining the meaning of a class or property. Shall be Aristotelian, formalized and normalized. Can be augmented with colloquial definitions." ;
  rdfs:range xsd:string .

obo:IAO_0000116 a rdf:Property ;
  rdfs:label "编者注" ;
  rdfs:comment "管理者注释用于其编辑器。它可能不包含在本体的出版版本中，所以它应该不包含最终用户了解本体所需的信息。" ;
  rdfs:range xsd:string .

obo:IAO_0000117 a rdf:Property ;
  rdfs:label "term editor" ;
  rdfs:comment "Name of editor entering the definition in the file. The definition editor is a point of contact for information regarding the term. The definition editor may be, but is not always, the author of the definition, which may have been worked upon by several people" ;
  rdfs:range xsd:string .

obo:IAO_0000118 a rdf:Property ;
  rdfs:label "alternative term" ;
  rdfs:comment "An alternative name for a class or property which means the same thing as the preferred name (semantically equivalent)" ;
  rdfs:range xsd:string .

obo:IAO_0000119 a rdf:Property ;
  rdfs:label "定义来源" ;
  rdfs:comment "formal citation, e.g. identifier in external database to indicate / attribute source(s) for the definition. Free text indicate / attribute source(s) for the definition. EXAMPLE: Author Name, URI, MeSH Term C04, PUBMED ID, Wiki uri on 31.01.2007" ;
  rdfs:range xsd:string .

obo:IAO_0000232 a rdf:Property ;
  rdfs:label "curator notes" ;
  rdfs:comment "An administrative note of use for a curator but of no use for a user" ;
  rdfs:range xsd:string .

obo:IAO_0000412 a rdf:Property ;
  rdfs:label "引自" ;
  rdfs:comment "外部术语/类，术语引入的本体" ;
  rdfs:range xsd:string .

obo:IAO_0000589 a rdf:Property ;
  rdfs:label "OBO foundry unique label" ;
  rdfs:range xsd:string .

obo:IAO_0000600 a rdf:Property ;
  rdfs:label "elucidation" ;
  rdfs:range xsd:string .

obo:IAO_0000601 a rdf:Property ;
  rdfs:label "has associated axiom(nl)" ;
  rdfs:range xsd:string .

obo:IAO_0000602 a rdf:Property ;
  rdfs:label "has associated axiom(fol)" ;
  rdfs:range xsd:string .

obo:MFOEM_000010 a rdf:Property ;
  rdfs:label "synonym" ;
  rdfs:range xsd:string .

obo:MFOEM_000165 a rdf:Property ;
  rdfs:label "tag display synonym" ;
  rdfs:range xsd:string .

obo:NCIT_A10 a rdf:Property ;
  rdfs:label "Has_CDRH_Parent" ;
  rdfs:comment "An association created to allow the source CDRH to assign a parent to each concept with the intent of creating a hierarchy that includes only terms in which they are the contributing source." ;
  rdfs:range xsd:string .

obo:NCIT_A11 a rdf:Property ;
  rdfs:label "Has_NICHD_Parent" ;
  rdfs:comment "An association created to allow the source NICHD to assign a parent to each concept with the intent of creating a hierarchy that includes only terms in which they are a contributing source." ;
  rdfs:range xsd:string .

obo:NCIT_A13 a rdf:Property ;
  rdfs:label "Related_To_Genetic_Biomarker" ;
  rdfs:comment "An association that indicates that a finding or lab test is related to a gene, possibly through a variant or product." ;
  rdfs:range xsd:string .

obo:NCIT_A14 a rdf:Property ;
  rdfs:label "Neoplasm_Has_Special_Category" ;
  rdfs:comment "An association that indicates that a neoplastic disease can have the characteristics defined by a Neoplasm by Special Category concept." ;
  rdfs:range xsd:string .

obo:NCIT_NHC0 a rdf:Property ;
  rdfs:label "code" ;
  rdfs:comment "A property representing a concept unique identifier within the NCI Enterprise Vocabulary Service's NCI Thesaurus." ;
  rdfs:range xsd:string .

obo:NCIT_P106 a rdf:Property ;
  rdfs:label "Semantic_Type" ;
  rdfs:comment "A property that represents a description of the sort of thing or category to which a concept belongs in the context of the UMLS semantic network." ;
  rdfs:range xsd:string .

obo:NCIT_P107 a rdf:Property ;
  rdfs:label "Display_Name" ;
  rdfs:comment "A property representing an alternative Preferred Name for use in some NCI systems." ;
  rdfs:range xsd:string .

obo:NCIT_P108 a rdf:Property ;
  rdfs:label "Preferred_Name" ;
  rdfs:comment "A property representing the word or phrase that NCI uses by preference to refer to the concept." ;
  rdfs:range xsd:string .

obo:NCIT_P207 a rdf:Property ;
  rdfs:label "UMLS_CUI" ;
  rdfs:comment "A property representing the concept unique identifier (CUI) assigned by the National Library of Medicine (NLM). If a concept in any NCI-maintained knowledgebase exists in the NLM Unified Medical Language System (UMLS), NCI includes the NLM CUI among the information we provide about the concept." ;
  rdfs:range xsd:string .

obo:NCIT_P208 a rdf:Property ;
  rdfs:label "NCI_META_CUI" ;
  rdfs:comment "A property representing the concept unique identifier (CUI) for those concepts that appear in NCI Metathesaurus but not in the National Library of Medicine Unified Medical Language System (NLM UMLS)." ;
  rdfs:range xsd:string .

obo:NCIT_P310 a rdf:Property ;
  rdfs:label "Concept_Status" ;
  rdfs:comment "A property used to indicate the standing of a concept in relation to currently accepted classifications and concepts. In NCI Thesaurus concept status subtype indicates concepts with unusual and problematic characteristics that should be evaluated by people and/or programs before those concept are used." ;
  rdfs:range xsd:string .

obo:NCIT_P317 a rdf:Property ;
  rdfs:label "FDA_Table" ;
  rdfs:comment "A property used to flag terms that are part of an FDA data standard manual, including Route of Administration, Dosage Form, Package Type and Potency." ;
  rdfs:range xsd:string .

obo:NCIT_P322 a rdf:Property ;
  rdfs:label "Contributing_Source" ;
  rdfs:comment "A property is used to indicate when a non-EVS entity has contributed to, and has a stake in, a concept. This is used where such entities, within or outside NCI, have indicated the need to be able to track their own concepts. A single concept can have multiple instances of this property if multiple entities have such a defined stake." ;
  rdfs:range xsd:string .

obo:NCIT_P325 a rdf:Property ;
  rdfs:label "ALT_DEFINITION" ;
  rdfs:comment "A property representing the English language definition of a concept from a source other than NCI." ;
  rdfs:range xsd:string .

obo:NCIT_P333 a rdf:Property ;
  rdfs:label "Use_For" ;
  rdfs:comment "A property representing a term that had been used in a coding system and then subsumed by the given NCIt concept." ;
  rdfs:range xsd:string .

obo:NCIT_P334 a rdf:Property ;
  rdfs:label "ICD-O-3_Code" ;
  rdfs:comment "A property representing the matching ICD-O-3 code for the NCI Thesaurus concept." ;
  rdfs:range xsd:string .

obo:NCIT_P363 a rdf:Property ;
  rdfs:label "Neoplastic_Status" ;
  rdfs:comment "A property representing the morphologic, clinical, and genetic profile of a neoplastic growth that defines it as benign, malignant, or of uncertain cancerous potential." ;
  rdfs:range xsd:string .

obo:NCIT_P366 a rdf:Property ;
  rdfs:label "Legacy_Concept_Name" ;
  rdfs:comment "A property representing a retired unique concept identifier created and stored as Concept Name by legacy EVS software. Use of these values was long discouraged, but continued as late as 2009 when creation of new values ceased and Concept Name was retired. Legacy values are intended solely to help resolve and update earlier coding." ;
  rdfs:range xsd:string .

obo:NCIT_P371 a rdf:Property ;
  rdfs:label "NICHD_Hierarchy_Term" ;
  rdfs:comment "A property representing a term chosen by NICHD to be used in the representation of the NICHD hierarchy." ;
  rdfs:range xsd:string .

obo:NCIT_P372 a rdf:Property ;
  rdfs:label "Publish_Value_Set" ;
  rdfs:comment "A property representing whether a value set is ready for publication in the browser." ;
  rdfs:range xsd:string .

obo:NCIT_P375 a rdf:Property ;
  rdfs:label "Maps_To" ;
  rdfs:comment "A property representing that a term in another terminology has been mapped to a term in NCIt and describes the relationship between the mapped terms." ;
  rdfs:range xsd:string .

obo:NCIT_P98 a rdf:Property ;
  rdfs:label "DesignNote" ;
  rdfs:comment "A property representing notations made by NCI vocabulary curators. They are intended to provide supplemental, unstructured information to the user or additional insight about the concept." ;
  rdfs:range xsd:string .

obo:OAE_0004334 a rdf:Property ;
  rdfs:label "has_MedDRA_id" ;
  rdfs:range xsd:string .

obo:OBI_0001847 a rdf:Property ;
  rdfs:label "ISA alternative term" ;
  rdfs:comment "An alternative term used by the ISA tools project (http://isa-tools.org)." ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:IAO_0000118 .

obo:OBI_9991118 a rdf:Property ;
  rdfs:label "IEDB alternative term" ;
  rdfs:comment "An alternative term used by the IEDB." ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:IAO_0000118 .

obo:RO_0002174 a rdf:Property ;
  rdfs:label "dubious_for_taxon" ;
  rdfs:comment "S dubious_for_taxon T if it is probably the case that no instances of S can be found in any instance of T." ;
  rdfs:range xsd:string .

obo:RO_0002175 a rdf:Property ;
  rdfs:label "present_in_taxon" ;
  rdfs:comment "S present_in_taxon T if some instance of T has some S. This does not means that all instances of T have an S - it may only be certain life stages or sexes that have S" ;
  rdfs:range xsd:string .

obo:RO_0002604 a rdf:Property ;
  rdfs:label "is_opposite_of" ;
  rdfs:comment "x is the opposite of y if there exists some distance metric M, and there exists no z such as M(x,z) <= M(x,y) or M(y,z) <= M(y,x)." ;
  rdfs:range xsd:string .

obo:UBPROP_0000001 a rdf:Property ;
  rdfs:label "external_definition" ;
  rdfs:comment "An alternate textual definition for a class taken unmodified from an external source. This definition may have been used to derive a generalized definition for the new class." ;
  rdfs:range xsd:string .

obo:UBPROP_0000002 a rdf:Property ;
  rdfs:label "axiom_lost_from_external_ontology" ;
  rdfs:comment "A textual description of an axiom loss in this ontology compared to an external ontology." ;
  rdfs:range xsd:string .

obo:UBPROP_0000003 a rdf:Property ;
  rdfs:label "homology_notes" ;
  rdfs:comment "Notes on the homology status of this class." ;
  rdfs:range xsd:string .

obo:UBPROP_0000007 a rdf:Property ;
  rdfs:label "has_relational_adjective" ;
  rdfs:range xsd:string .

obo:UBPROP_0000008 a rdf:Property ;
  rdfs:label "taxon_notes" ;
  rdfs:comment "Notes on the how instances of this class vary across species." ;
  rdfs:range xsd:string .

obo:UBPROP_0000011 a rdf:Property ;
  rdfs:label "development_notes" ;
  rdfs:comment "Notes on the ontogenic development of instances of this class." ;
  rdfs:range xsd:string .

obo:UBPROP_0000012 a rdf:Property ;
  rdfs:label "external_ontology_notes" ;
  rdfs:comment "Notes on how similar or equivalent classes are represented in other ontologies." ;
  rdfs:range xsd:string .

obo:UBPROP_0000202 a rdf:Property ;
  rdfs:label "fma_set_term" ;
  rdfs:range xsd:string .

<http://purl.obolibrary.org/obo/mondo#excluded_subClassOf> a rdf:Property ;
  rdfs:label "excluded subClassOf" ;
  rdfs:range xsd:string .

<http://purl.obolibrary.org/obo/ncbitaxon#has_rank> a rdf:Property ;
  rdfs:label "has_rank" ;
  rdfs:comment "A metadata relation between a class and its taxonomic rank (eg species, family)" ;
  rdfs:range xsd:string .

<http://xmlns.com/foaf/0.1/depicted_by> a rdf:Property ;
  rdfs:label "depicted by" ;
  rdfs:range xsd:string .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#fromArticle> a rdf:Property ;
  rdfs:comment "Concept is taken from other resources than PubMed" ;
  rdfs:range xsd:string .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#fromEPILONT> a rdf:Property ;
  rdfs:comment "concept is derived from Epilepsy Ontology (EPILONT)  https://bioportal.bioontology.org/ontologies/EPILONT" ;
  rdfs:range xsd:string .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#fromESSO> a rdf:Property ;
  rdfs:comment "concept is derived from Epilepsy Syndrome Seizure Ontology (ESSO) https://bioportal.bioontology.org/ontologies/ESSO" ;
  rdfs:range xsd:string .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#fromEpSO> a rdf:Property ;
  rdfs:comment "concept isderived from Epilepsy and Seizure Ontology (EpSO)  https://bioportal.bioontology.org/ontologies/EPSO" ;
  rdfs:range xsd:string .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#fromILAE> a rdf:Property ;
  rdfs:comment "concept is derived from International League Against Epilpesy (ILAE)  seizure classification (https://www.epilepsydiagnosis.org/index.html" ;
  rdfs:range xsd:string .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#fromNCBIBook> a rdf:Property ;
  rdfs:comment "Concept is taken from NCBI book" ;
  rdfs:range xsd:string .

<https://bio.scai.fraunhofer.de/ontology/epilepsy#fromPubMed> a rdf:Property ;
  rdfs:comment "Concepts is taken from PubMed article" ;
  rdfs:range xsd:string .
