PREFIX obo: <http://purl.obolibrary.org/obo/>
PREFIX rdf: <http://www.w3.org/1999/02/22-rdf-syntax-ns#>
PREFIX rdfs: <http://www.w3.org/2000/01/rdf-schema#>
PREFIX xsd: <http://www.w3.org/2001/XMLSchema#>

obo:NCBITaxon_131567 a rdfs:Class ;
  rdfs:label "cellular organism" ;
  rdfs:subClassOf obo:COB_0000022 .

obo:COB_0000801 a rdf:Property ;
  rdfs:label "has number of atomic nuclei"@en ;
  rdfs:domain obo:BFO_0000040 ;
  rdfs:range <https://w3id.org/linkml/Any> .

obo:IAO_0000033 a rdfs:Class ;
  rdfs:label "directive information entity"@en ;
  rdfs:comment "An information content entity whose concretizations indicate to their bearer how to realize them in a process."@en ;
  rdfs:subClassOf obo:IAO_0000030 .

obo:IAO_0000136 a rdf:Property ;
  rdfs:label "is about"@en ;
  rdfs:domain obo:IAO_0000030 ;
  rdfs:range <https://w3id.org/linkml/Any> .

obo:COB_0000056 a rdfs:Class ;
  rdfs:label "obsolete immaterial anatomical entity" .

obo:MOP_0000543 a rdfs:Class ;
  rdfs:label "physico-chemical process" ;
  rdfs:comment "A process in which at least one of the participants is a molecule." ;
  rdfs:subClassOf obo:BFO_0000015 .

obo:RO_0002233 a rdf:Property ;
  rdfs:label "has input"@en ;
  rdfs:comment "p has input c iff: p is a process, c is a material entity, c is a participant in p, c is present at the start of p, and the state of c is modified during p." ;
  rdfs:domain obo:BFO_0000015 ;
  rdfs:range <https://w3id.org/linkml/Any> .

obo:BFO_0000055 a rdf:Property ;
  rdfs:label "realizes"@en ;
  rdfs:comment "Paraphrase of elucidation: a relation between a process and a realizable entity, where there is some material entity that is bearer of the realizable entity and participates in the process, and the realizable entity comes to be realized in the course of the process"@en ;
  rdfs:domain obo:BFO_0000015 ;
  rdfs:range obo:BFO_0000017 .

obo:ENVO_01001110 a rdfs:Class ;
  rdfs:label "ecosystem"@en ;
  rdfs:comment "An environmental system which includes both living and non-living components." ;
  rdfs:subClassOf obo:BFO_0000040 .

obo:GO_0110165 a rdfs:Class ;
  rdfs:label "cellular anatomical entity" ;
  rdfs:comment "A part of a cellular organism that is either an immaterial entity or a material entity with granularity above the level of a protein complex but below that of an anatomical system. Or, a substance produced by a cellular organism with granularity above the level of a protein complex." ;
  rdfs:subClassOf obo:GO_0005575 , obo:UBERON_0000465 .

obo:BFO_0000051 a rdf:Property ;
  rdfs:label "has part"@en ;
  rdfs:comment "a core relation that holds between a whole and its part"@en ;
  rdfs:range <https://w3id.org/linkml/Any> .

obo:BFO_0000034 a rdfs:Class ;
  rdfs:label "function"@en ;
  rdfs:subClassOf obo:BFO_0000016 .

obo:BFO_0000017 a rdfs:Class ;
  rdfs:label "realizable entity"@en ;
  rdfs:subClassOf obo:COB_0000502 .

obo:UBERON_0000465 a rdfs:Class ;
  rdfs:label "material anatomical entity" ;
  rdfs:comment "Anatomical entity that has mass." ;
  rdfs:subClassOf obo:BFO_0000040 , obo:UBERON_0001062 .

obo:COB_0000080 a rdfs:Class ;
  rdfs:label "complex of molecules"@en ;
  rdfs:comment "A complex of two or more molecules that are not covalently bound."@en ;
  rdfs:subClassOf obo:BFO_0000040 .

obo:COB_0000022 a rdfs:Class ;
  rdfs:label "organism"@en ;
  rdfs:comment "A material entity that is a maximal functionally integrated unit that develops from a program encoded in a genome"@en ;
  rdfs:subClassOf obo:UBERON_0000465 .

obo:COB_0000122 a rdfs:Class ;
  rdfs:label "obsolete physical information carrier" .

obo:COB_0000011 a rdfs:Class ;
  rdfs:label "atom"@en ;
  rdfs:comment "A material entity consisting of exactly one atomic nucleus and the electron(s) orbiting it."@en ;
  rdfs:subClassOf obo:BFO_0000040 .

obo:COB_0000800 a rdf:Property ;
  rdfs:label "has atomic number"@en ;
  rdfs:comment "Number of protons in an atomic nucleus"@en ;
  rdfs:domain obo:COB_0000011 ;
  rdfs:range <https://w3id.org/linkml/Any> .

obo:BFO_0000029 a rdfs:Class ;
  rdfs:label "site"@en ;
  rdfs:subClassOf obo:BFO_0000141 .

obo:GO_0044423 a rdfs:Class ;
  rdfs:label "virion component" ;
  rdfs:comment "Any constituent part of a virion, a complete fully infectious extracellular virus particle." ;
  rdfs:subClassOf obo:GO_0005575 .

obo:COB_0000032 a rdfs:Class ;
  rdfs:label "obsolete geographical location" .

obo:PATO_0002193 a rdfs:Class ;
  rdfs:label "electric charge" ;
  rdfs:comment "A molecular quality that inheres in a molecular entity by virtue of the overall electric charge of the molecule, which is due to a comparison between the total number of electrons and the total number of protons." ;
  rdfs:subClassOf obo:COB_0000502 .

obo:COB_0001000 a rdfs:Class ;
  rdfs:label "exposure of organism"@en ;
  rdfs:comment "A process during which an organism comes into contact with another entity."@en ;
  rdfs:subClassOf obo:BFO_0000015 .

obo:RO_0000057 a rdf:Property ;
  rdfs:label "has participant"@en ;
  rdfs:comment "a relation between a process and a continuant, in which the continuant is somehow involved in the process"@en ;
  rdfs:range <https://w3id.org/linkml/Any> .

obo:COB_0000014 a rdfs:Class ;
  rdfs:label "obsolete macromolecular entity" .

obo:UBERON_0001062 a rdfs:Class ;
  rdfs:label "anatomical entity" ;
  rdfs:comment "Biological entity that is either an individual member of a biological species or constitutes the structural organization of an individual member of a biological species." .

obo:COB_0000021 a rdfs:Class ;
  rdfs:label "gross anatomical part"@en ;
  rdfs:comment "A part of a multicellular organism that is a collection of cell components that are not all contained in one cell."@en ;
  rdfs:subClassOf obo:UBERON_0000465 .

obo:BFO_0000141 a rdfs:Class ;
  rdfs:label "immaterial entity"@en .

obo:BFO_0000040 a rdfs:Class ;
  rdfs:label "material entity"@en .

obo:OBI_0000070 a rdfs:Class ;
  rdfs:label "assay"@en ;
  rdfs:comment "A planned process that has the objective to produce information about a material entity (the evaluant) by examining it."@en ;
  rdfs:subClassOf obo:COB_0000035 .

obo:OBI_0000293 a rdf:Property ;
  rdfs:label "has specified input"@en ;
  rdfs:comment "The inverse property of is specified input of" ;
  rdfs:domain obo:COB_0000035 ;
  rdfs:range <https://w3id.org/linkml/Any> .

obo:OBI_0000299 a rdf:Property ;
  rdfs:label "has specified output"@en ;
  rdfs:comment "The inverse property of is specified output of" ;
  rdfs:domain obo:COB_0000035 ;
  rdfs:range <https://w3id.org/linkml/Any> .

obo:COB_0000110 a rdfs:Class ;
  rdfs:label "material processing"@en ;
  rdfs:comment "A completely executed planned process that intends to output material entities from input material entities"@en ;
  rdfs:subClassOf obo:COB_0000035 .

obo:CL_0000000 a rdfs:Class ;
  rdfs:label "cell" ;
  rdfs:comment "A material entity of anatomical origin (part of or deriving from an organism) that has as its parts a maximally connected cell compartment surrounded by a plasma membrane." ;
  rdfs:subClassOf obo:UBERON_0000465 .

obo:BFO_0000023 a rdfs:Class ;
  rdfs:label "role"@en ;
  rdfs:subClassOf obo:BFO_0000017 .

obo:CHEBI_30222 a rdfs:Class ;
  rdfs:label "neutron" ;
  rdfs:comment "Nuclear particle of zero charge, spin 1/2 and rest mass of 1.008664904(14) u." ;
  rdfs:subClassOf obo:CHEBI_36342 .

obo:GO_0008150 a rdfs:Class ;
  rdfs:label "biological process"@en ;
  rdfs:comment "A biological process is the execution of a genetically-encoded biological module or program. It consists of all the steps required to achieve the specific biological objective of the module. A biological process is accomplished by a particular set of molecular functions carried out by specific gene products (or macromolecular complexes), often in a highly regulated manner and in a particular temporal sequence." ;
  rdfs:subClassOf obo:BFO_0000015 .

obo:GO_0003674 a rdfs:Class ;
  rdfs:label "gene product or complex activity"@en ;
  rdfs:comment "A molecular process that can be carried out by the action of a single macromolecular machine, usually via direct physical interactions with other molecular entities. Function in this sense denotes an action, or activity, that a gene product (or a complex) performs." ;
  rdfs:subClassOf obo:BFO_0000015 .

obo:BFO_0000016 a rdfs:Class ;
  rdfs:label "disposition"@en ;
  rdfs:subClassOf obo:BFO_0000017 .

obo:IAO_0000030 a rdfs:Class ;
  rdfs:label "information content entity"@en ;
  rdfs:comment "A generically dependent continuant that is about some thing."@en .

obo:UBERON_0000466 a rdfs:Class ;
  rdfs:label "immaterial anatomical entity" ;
  rdfs:comment "Anatomical entity that has no mass." ;
  rdfs:subClassOf obo:BFO_0000141 , obo:UBERON_0001062 .

obo:ENVO_02500000 a rdfs:Class ;
  rdfs:label "environmental system process"@en ;
  rdfs:comment "A process in which includes the components of an environmental system as participants." ;
  rdfs:subClassOf obo:BFO_0000015 .

obo:OBI_0000260 a rdfs:Class ;
  rdfs:label "plan"@en ;
  rdfs:comment "A plan is a realizable entity that is the inheres in a bearer who is committed to realizing it as a completely executed planned process."@en ;
  rdfs:subClassOf obo:BFO_0000017 .

obo:RO_0000059 a rdf:Property ;
  rdfs:label "concretizes"@en ;
  rdfs:comment "A relationship between a specifically dependent continuant and a generically dependent continuant, in which the generically dependent continuant depends on some independent continuant in virtue of the fact that the specifically dependent continuant also depends on that same independent continuant. Multiple specifically dependent continuants can concretize the same generically dependent continuant."@en ;
  rdfs:range <https://w3id.org/linkml/Any> .

obo:COB_0000082 a rdfs:Class ;
  rdfs:label "planned process"@en ;
  rdfs:comment "A process that is initiated by an agent who intends to carry out a plan to achieve an objective through one or more actions as described in a plan specification."@en ;
  rdfs:subClassOf obo:BFO_0000015 .

obo:COB_0000026 a rdfs:Class ;
  rdfs:label "processed material entity"@en ;
  rdfs:comment "A material entity processed by human activity with an intent to produce it."@en ;
  rdfs:subClassOf obo:BFO_0000040 .

obo:OBI_0000312 a rdf:Property ;
  rdfs:label "is specified output of"@en ;
  rdfs:comment "A relation between a completely executed planned process and a continuant participating in that process. The presence of the continuant at the end of the process is explicitly specified in the objective specification which the process realizes the concretization of."@en ;
  rdfs:range obo:COB_0000035 .

obo:IAO_0000007 a rdfs:Class ;
  rdfs:label "action specification"@en ;
  rdfs:comment "A directive information entity that describes an action the bearer will take."@en ;
  rdfs:subClassOf obo:IAO_0000033 .

obo:BFO_0000015 a rdfs:Class ;
  rdfs:label "process"@en .

obo:CHEBI_33252 a rdfs:Class ;
  rdfs:label "atomic nucleus" ;
  rdfs:comment "A nucleus is the positively charged central portion of an atom, excluding the orbital electrons." ;
  rdfs:subClassOf obo:CHEBI_36342 .

obo:COB_0000502 a rdfs:Class ;
  rdfs:label "characteristic"@en .

obo:COB_0000020 a rdfs:Class ;
  rdfs:label "obsolete subcellular structure" .

obo:IAO_0000104 a rdfs:Class ;
  rdfs:label "plan specification"@en ;
  rdfs:comment "A directive information entity with action specifications and objective specifications as parts, and that may be concretized as a realizable entity that, if realized, is realized in a process in which the bearer tries to achieve the objectives by taking the actions specified."@en ;
  rdfs:subClassOf obo:IAO_0000033 .

obo:CHEBI_10545 a rdfs:Class ;
  rdfs:label "electron" ;
  rdfs:comment "Elementary particle not affected by the strong force having a spin 1/2, a negative elementary charge and a rest mass of 0.000548579903(13) u, or 0.51099906(15) MeV." ;
  rdfs:subClassOf obo:CHEBI_36342 .

obo:COB_0000116 a rdfs:Class ;
  rdfs:label "obsolete cellular membrane" .

obo:COB_0000073 a rdfs:Class ;
  rdfs:label "obsolete gene product" .

obo:COB_0000049 a rdfs:Class ;
  rdfs:label "nucleic acid chain"@en ;
  rdfs:comment "A molecule that consists of nucleotides (unmodified nucleotide residues and/or modified nucleotide residues) linked by phosphodiester bonds or derivatives of such bonds."@en ;
  rdfs:subClassOf obo:COB_0000013 .

obo:COB_0000005 a rdfs:Class ;
  rdfs:label "obsolete elementary charge" .

obo:PO_0025131 a rdfs:Class ;
  rdfs:label "plant anatomical entity" ;
  rdfs:comment "An anatomical entity that is or was part of a plant." ;
  rdfs:subClassOf obo:UBERON_0000465 .

obo:PR_000000001 a rdfs:Class ;
  rdfs:label "protein" ;
  rdfs:comment "An amino acid chain that is produced de novo by ribosome-mediated translation of a genetically-encoded mRNA, and any derivatives thereof." ;
  rdfs:subClassOf obo:PR_000018263 .

obo:OBI_0000066 a rdfs:Class ;
  rdfs:label "investigation"@en ;
  rdfs:comment "a planned process that consists of parts: planning, study design execution, documentation and which produce conclusion(s)."@en ;
  rdfs:subClassOf obo:COB_0000035 .

obo:COB_0000083 a rdfs:Class ;
  rdfs:label "failed planned process"@en ;
  rdfs:subClassOf obo:COB_0000082 .

obo:GO_0032991 a rdfs:Class ;
  rdfs:label "protein-containing complex" ;
  rdfs:comment "A stable assembly of two or more macromolecules, i.e. proteins, nucleic acids, carbohydrates or lipids, in which at least one component is a protein and the constituent parts function together." ;
  rdfs:subClassOf obo:COB_0000080 , obo:GO_0005575 .

obo:CHEBI_24636 a rdfs:Class ;
  rdfs:label "proton" ;
  rdfs:comment "Nuclear particle of charge number +1, spin 1/2 and rest mass of 1.007276470(12) u." ;
  rdfs:subClassOf obo:CHEBI_36342 .

obo:ENVO_01000813 a rdfs:Class ;
  rdfs:label "geophysical entity"@en ;
  rdfs:comment "A material part of an astronomical body." ;
  rdfs:subClassOf obo:BFO_0000040 .

obo:CHEBI_36342 a rdfs:Class ;
  rdfs:label "subatomic particle" ;
  rdfs:comment "A particle smaller than an atom." ;
  rdfs:subClassOf obo:BFO_0000040 .

obo:IAO_0000109 a rdfs:Class ;
  rdfs:label "measurement datum"@en ;
  rdfs:comment "A measurement datum is an information content entity that is a recording of the output of a measurement such as produced by a device."@en ;
  rdfs:subClassOf obo:IAO_0000027 .

obo:COB_0000077 a rdfs:Class ;
  rdfs:label "obsolete action specification" .

obo:PATO_0000125 a rdfs:Class ;
  rdfs:label "mass" ;
  rdfs:comment "A physical quality that inheres in a bearer by virtue of the proportion of the bearer's amount of matter." ;
  rdfs:subClassOf obo:COB_0000502 .

obo:PR_000018263 a rdfs:Class ;
  rdfs:label "amino acid chain" ;
  rdfs:comment "An organic amino compound that consists of amino acid residues (unmodified amino-acid residues and/or modified amino-acid residues) linked by peptide bonds or derivatives of such bonds." ;
  rdfs:subClassOf obo:COB_0000013 .

obo:COB_0000013 a rdfs:Class ;
  rdfs:label "molecule"@en ;
  rdfs:comment "A material entity that consists of two or more atoms that are all connected via covalent bonds such that any atom can be transitively connected with any other atom."@en ;
  rdfs:subClassOf obo:BFO_0000040 .

obo:PCO_0000000 a rdfs:Class ;
  rdfs:label "collection of organisms"@en ;
  rdfs:comment "A material entity that consists of two or more organisms, viruses, or viroids."@en ;
  rdfs:subClassOf obo:BFO_0000040 .

<https://w3id.org/linkml/Any> a rdfs:Class ;
  rdfs:comment "An unconstrained type or object" .

obo:IAO_0000005 a rdfs:Class ;
  rdfs:label "objective specification"@en ;
  rdfs:comment "A directive information entity that describes an intended process endpoint. When part of a plan specification the concretization is realized in a planned process in which the bearer tries to effect the world so that the process endpoint is achieved."@en ;
  rdfs:subClassOf obo:IAO_0000033 .

obo:OBI_0200000 a rdfs:Class ;
  rdfs:label "data transformation"@en ;
  rdfs:comment "A completely executed planned process that produces output data from input data."@en ;
  rdfs:subClassOf obo:COB_0000035 .

obo:GO_0005575 a rdfs:Class ;
  rdfs:label "cellular_component" ;
  rdfs:comment "A location, relative to cellular compartments and structures, occupied by a macromolecular machine. There are three types of cellular components described in the gene ontology: (1) the cellular anatomical entity where a gene product carries out a molecular function (e.g., plasma membrane, cytoskeleton) or membrane-enclosed compartments (e.g., mitochondrion); (2) virion components, where viral proteins act, and (3) the stable macromolecular complexes of which gene product are parts (e.g., the clathrin complex)." ;
  rdfs:subClassOf obo:BFO_0000040 .

obo:COB_0001300 a rdfs:Class ;
  rdfs:label "device"@en ;
  rdfs:comment "A processed material entity which is designed to be capable of a process."@en ;
  rdfs:subClassOf obo:COB_0000026 .

obo:RO_0002215 a rdf:Property ;
  rdfs:label "capable of"@en ;
  rdfs:comment "A relation between a material entity (such as a cell) and a process, in which the material entity has the ability to carry out the process." ;
  rdfs:range obo:BFO_0000015 .

obo:NCBITaxon_10239 a rdfs:Class ;
  rdfs:label "virus"@en ;
  rdfs:subClassOf obo:COB_0000022 .

obo:IAO_0000027 a rdfs:Class ;
  rdfs:label "data item"@en ;
  rdfs:comment "An information content entity that is intended to be a truthful statement about something (modulo, e.g., measurement precision or other systematic errors) and is constructed/acquired by a method which reliably tends to produce (approximately) truthful statements."@en ;
  rdfs:subClassOf obo:IAO_0000030 .

obo:COB_0000035 a rdfs:Class ;
  rdfs:label "completely executed planned process"@en ;
  rdfs:subClassOf obo:COB_0000082 .

obo:BFO_0000050 a rdf:Property ;
  rdfs:label "part of"@en ;
  rdfs:comment "a core relation that holds between a part and its whole"@en ;
  rdfs:range <https://w3id.org/linkml/Any> .

obo:COB_0000016 a rdf:Property ;
  rdfs:label "executed by"@en ;
  rdfs:range <https://w3id.org/linkml/Any> .

obo:COB_0000081 a rdf:Property ;
  rdfs:label "intended to realize"@en ;
  rdfs:range <https://w3id.org/linkml/Any> .

obo:COB_0000084 a rdf:Property ;
  rdfs:label "has plan"@en ;
  rdfs:range <https://w3id.org/linkml/Any> .

obo:COB_0000085 a rdf:Property ;
  rdfs:label "intended plan process type"@en ;
  rdfs:range <https://w3id.org/linkml/Any> .

obo:COB_0000511 a rdf:Property ;
  rdfs:label "has quantity"@en ;
  rdfs:range <https://w3id.org/linkml/Any> .

obo:COB_0000803 a rdf:Property ;
  rdfs:label "has inchi string"@en ;
  rdfs:range <https://w3id.org/linkml/Any> .

obo:IAO_0000115 a rdf:Property ;
  rdfs:label "definition" ;
  rdfs:range xsd:string .

obo:IAO_0000116 a rdf:Property ;
  rdfs:label "editor note"@en ;
  rdfs:range xsd:string .

obo:IAO_0100001 a rdf:Property ;
  rdfs:label "term replaced by"@en ;
  rdfs:range xsd:string .

obo:OBI_0000295 a rdf:Property ;
  rdfs:label "is specified input of"@en ;
  rdfs:comment "A relation between a completely executed planned process and a continuant participating in that process that is not created during the process. The presence of the continuant during the process is explicitly specified in the plan specification which the process realizes the concretization of." ;
  rdfs:range obo:COB_0000035 .

obo:RO_0000052 a rdf:Property ;
  rdfs:label "characteristic of"@en ;
  rdfs:comment "a relation between a specifically dependent continuant (the characteristic) and any other entity (the bearer), in which the characteristic depends on the bearer for its existence."@en ;
  rdfs:range <https://w3id.org/linkml/Any> .

obo:RO_0000053 a rdf:Property ;
  rdfs:label "has characteristic"@en ;
  rdfs:comment "Inverse of characteristic_of"@en ;
  rdfs:range <https://w3id.org/linkml/Any> .

obo:RO_0000056 a rdf:Property ;
  rdfs:label "participates in"@en ;
  rdfs:comment "a relation between a continuant and a process, in which the continuant is somehow involved in the process"@en ;
  rdfs:range <https://w3id.org/linkml/Any> .

obo:RO_0000058 a rdf:Property ;
  rdfs:label "is concretized as"@en ;
  rdfs:comment "A relationship between a generically dependent continuant and a specifically dependent continuant, in which the generically dependent continuant depends on some independent continuant in virtue of the fact that the specifically dependent continuant also depends on that same independent continuant. A generically dependent continuant may be concretized as multiple specifically dependent continuants."@en ;
  rdfs:range <https://w3id.org/linkml/Any> .

obo:RO_0001000 a rdf:Property ;
  rdfs:label "derives from"@en ;
  rdfs:comment "a relation between two distinct material entities, the new entity and the old entity, in which the new entity begins to exist when the old entity ceases to exist, and the new entity inherits the significant portion of the matter of the old entity"@en ;
  rdfs:range <https://w3id.org/linkml/Any> .

obo:RO_0001015 a rdf:Property ;
  rdfs:label "location of"@en ;
  rdfs:comment "a relation between two independent continuants, the location and the target, in which the target is entirely within the location"@en ;
  rdfs:range <https://w3id.org/linkml/Any> .

obo:RO_0001025 a rdf:Property ;
  rdfs:label "located in"@en ;
  rdfs:comment "a relation between two independent continuants, the target and the location, in which the target is entirely within the location"@en ;
  rdfs:range <https://w3id.org/linkml/Any> .

obo:RO_0002219 a rdf:Property ;
  rdfs:label "surrounded by"@en ;
  rdfs:comment "x surrounded_by y if and only if (1) x is adjacent to y and for every region r that is adjacent to x, r overlaps y (2) the shared boundary between x and y occupies the majority of the outermost boundary of x" ;
  rdfs:range <https://w3id.org/linkml/Any> .

obo:RO_0002221 a rdf:Property ;
  rdfs:label "surrounds"@en ;
  rdfs:comment "inverse of surrounded by" ;
  rdfs:range <https://w3id.org/linkml/Any> .

obo:RO_0002234 a rdf:Property ;
  rdfs:label "has output"@en ;
  rdfs:comment "p has output c iff c is a participant in p, c is present at the end of p, and c is not present in the same state at the beginning of p." ;
  rdfs:range <https://w3id.org/linkml/Any> .

obo:RO_0002333 a rdf:Property ;
  rdfs:label "enabled by"@en ;
  rdfs:comment "inverse of enables" ;
  rdfs:range <https://w3id.org/linkml/Any> .