@prefix rdf: <http://www.w3.org/1999/02/22-rdf-syntax-ns#> .
@prefix owl: <http://www.w3.org/2002/07/owl#> .
@prefix rdfs: <http://www.w3.org/2000/01/rdf-schema#> .
@prefix xml: <http://www.w3.org/XML/1998/namespace> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<http://purl.obolibrary.org/obo/cio.owl> a owl:Ontology;
  <http://www.geneontology.org/formats/oboInOwl#hasOBOFormatVersion> "1.4";
  <http://www.geneontology.org/formats/oboInOwl#default-namespace> "cio";
  owl:versionIRI <http://purl.obolibrary.org/obo/cio/releases/2015-03-10/cio.owl> .

<http://purl.obolibrary.org/obo/IAO_0000115> a owl:AnnotationProperty;
  rdfs:label "definition" .

<http://purl.obolibrary.org/obo/cio/#bgee_not_trusted> a owl:AnnotationProperty;
  rdfs:comment "Terms that are considered not trusted by the Bgee team, related to assertions needing additional support.";
  rdfs:subPropertyOf <http://www.geneontology.org/formats/oboInOwl#SubsetProperty> .

<http://www.geneontology.org/formats/oboInOwl#SubsetProperty> a owl:AnnotationProperty;
  rdfs:label "subset_property" .

<http://www.geneontology.org/formats/oboInOwl#hasDbXref> a owl:AnnotationProperty;
  rdfs:label "database_cross_reference" .

<http://www.geneontology.org/formats/oboInOwl#hasExactSynonym> a owl:AnnotationProperty;
  rdfs:label "has_exact_synonym" .

<http://www.geneontology.org/formats/oboInOwl#hasOBOFormatVersion> a owl:AnnotationProperty;
  rdfs:label "has_obo_format_version" .

<http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym> a owl:AnnotationProperty .

<http://www.geneontology.org/formats/oboInOwl#id> a owl:AnnotationProperty .

<http://www.geneontology.org/formats/oboInOwl#inSubset> a owl:AnnotationProperty;
  rdfs:label "in_subset" .

<http://www.geneontology.org/formats/oboInOwl#shorthand> a owl:AnnotationProperty;
  rdfs:label "shorthand" .

rdfs:comment a owl:AnnotationProperty .

rdfs:label a owl:AnnotationProperty .

<http://purl.obolibrary.org/obo/has_confidence_element> a owl:ObjectProperty;
  rdfs:label "has confidence element"@en;
  <http://www.geneontology.org/formats/oboInOwl#shorthand> "has_confidence_element";
  <http://purl.obolibrary.org/obo/IAO_0000115> "X has confidence element Y iff X is a confidence information statement and Y is an associated confidence information element, used to define the statement.";
  rdfs:domain <http://purl.obolibrary.org/obo/CIO_0000000>;
  rdfs:range <http://purl.obolibrary.org/obo/CIO_0000040> .

<http://purl.obolibrary.org/obo/has_confidence_level> a owl:ObjectProperty;
  rdfs:label "has confidence level"@en;
  <http://www.geneontology.org/formats/oboInOwl#shorthand> "has_confidence_level";
  <http://purl.obolibrary.org/obo/IAO_0000115> "X has confidence level Y iff X is a confidence information statement and Y is it associated confidence information level.";
  rdfs:range <http://purl.obolibrary.org/obo/CIO_0000028>;
  rdfs:subPropertyOf <http://purl.obolibrary.org/obo/has_confidence_element>;
  rdfs:domain _:5a090 .

_:5a090 a owl:Class;
  owl:intersectionOf _:5a0a0 .

_:5a0a0 rdf:first <http://purl.obolibrary.org/obo/CIO_0000000>;
  rdf:rest _:5a0c0 .

_:5a0c0 rdf:first _:5a0b0;
  rdf:rest rdf:nil .

_:5a0b0 a owl:Restriction;
  owl:onProperty <http://purl.obolibrary.org/obo/has_evidence_concordance>;
  owl:allValuesFrom _:5a0d0 .

_:5a0d0 a owl:Class;
  owl:complementOf <http://purl.obolibrary.org/obo/CIO_0000035> .

<http://purl.obolibrary.org/obo/has_evidence_concordance> a owl:ObjectProperty;
  rdfs:label "has evidence concordance"@en;
  <http://www.geneontology.org/formats/oboInOwl#shorthand> "has_evidence_concordance";
  <http://purl.obolibrary.org/obo/IAO_0000115> "X has evidence concordance Y iff X is a confidence information statement and Y is it associated evidence concordance.";
  rdfs:domain <http://purl.obolibrary.org/obo/CIO_0000000>;
  rdfs:range <http://purl.obolibrary.org/obo/CIO_0000032>;
  rdfs:subPropertyOf <http://purl.obolibrary.org/obo/has_confidence_element> .

<http://purl.obolibrary.org/obo/has_evidence_type_concordance> a owl:ObjectProperty;
  rdfs:label "has evidence type concordance"@en;
  <http://www.geneontology.org/formats/oboInOwl#shorthand> "has_evidence_type_concordance";
  <http://purl.obolibrary.org/obo/IAO_0000115> "X has evidence type concordance Y iff X is a confidence information statement and Y is it associated evidence type concordance.";
  rdfs:range <http://purl.obolibrary.org/obo/CIO_0000041>;
  rdfs:subPropertyOf <http://purl.obolibrary.org/obo/has_confidence_element>;
  rdfs:domain _:5a0e0 .

_:5a0e0 a owl:Class;
  owl:intersectionOf _:5a0f0 .

_:5a0f0 rdf:first <http://purl.obolibrary.org/obo/CIO_0000000>;
  rdf:rest _:5a110 .

_:5a110 rdf:first _:5a100;
  rdf:rest rdf:nil .

_:5a100 a owl:Restriction;
  owl:onProperty <http://purl.obolibrary.org/obo/has_evidence_concordance>;
  owl:allValuesFrom <http://purl.obolibrary.org/obo/CIO_0000043> .

<http://purl.obolibrary.org/obo/provides_greater_confidence_than> a owl:ObjectProperty,
    owl:TransitiveProperty;
  rdfs:label "provides greater confidence than"@en;
  <http://www.geneontology.org/formats/oboInOwl#shorthand> "provides_greater_confidence_than";
  <http://purl.obolibrary.org/obo/IAO_0000115> "X provides greater confidence than Y iff both X and Y provide a confidence information level, and the level of confidence provided by X is greater than the level of confidence provided by Y.";
  rdfs:domain <http://purl.obolibrary.org/obo/CIO_0000028>;
  rdfs:range <http://purl.obolibrary.org/obo/CIO_0000028> .

<http://purl.obolibrary.org/obo/CIO_0000000> a owl:Class;
  rdfs:label "confidence information statement";
  owl:equivalentClass _:5a120, _:5a2f0;
  rdfs:subClassOf _:5a3e0, _:5a3f0, _:5a400, _:5a410, _:5a420, _:5a430, _:5a440;
  owl:disjointWith <http://purl.obolibrary.org/obo/CIO_0000040>;
  <http://purl.obolibrary.org/obo/IAO_0000115> "A statement providing information about the confidence in an assertion, meaning, an information about the level of certainty that an assertion is correct.";
  <http://www.geneontology.org/formats/oboInOwl#id> "CIO:0000000";
  rdfs:comment "Quality and confidence are distinct concepts: quality refers to the value of a source or of an annotation, whereas confidence refers to the level of certainty that an assertion is correct." .

_:5a120 a owl:Class;
  owl:unionOf _:5a140 .

_:5a140 rdf:first _:5a130;
  rdf:rest _:5a220 .

_:5a130 a owl:Class;
  owl:intersectionOf _:5a160 .

_:5a160 rdf:first _:5a150;
  rdf:rest _:5a180 .

_:5a150 a owl:Restriction;
  owl:onProperty <http://purl.obolibrary.org/obo/has_evidence_concordance>;
  owl:allValuesFrom <http://purl.obolibrary.org/obo/CIO_0000042> .

_:5a180 rdf:first _:5a170;
  rdf:rest _:5a1a0 .

_:5a170 a owl:Restriction;
  owl:onProperty <http://purl.obolibrary.org/obo/has_confidence_element>;
  owl:onClass <http://purl.obolibrary.org/obo/CIO_0000040>;
  owl:minQualifiedCardinality "1"^^xsd:nonNegativeInteger .

_:5a1a0 rdf:first _:5a190;
  rdf:rest _:5a1c0 .

_:5a190 a owl:Restriction;
  owl:onProperty <http://purl.obolibrary.org/obo/has_confidence_level>;
  owl:onClass <http://purl.obolibrary.org/obo/CIO_0000028>;
  owl:minQualifiedCardinality "0"^^xsd:nonNegativeInteger .

_:5a1c0 rdf:first _:5a1b0;
  rdf:rest _:5a1e0 .

_:5a1b0 a owl:Restriction;
  owl:onProperty <http://purl.obolibrary.org/obo/has_evidence_type_concordance>;
  owl:onClass <http://purl.obolibrary.org/obo/CIO_0000041>;
  owl:qualifiedCardinality "0"^^xsd:nonNegativeInteger .

_:5a1e0 rdf:first _:5a1d0;
  rdf:rest _:5a200 .

_:5a1d0 a owl:Restriction;
  owl:onProperty <http://purl.obolibrary.org/obo/has_confidence_element>;
  owl:onClass <http://purl.obolibrary.org/obo/CIO_0000040>;
  owl:maxQualifiedCardinality "2"^^xsd:nonNegativeInteger .

_:5a200 rdf:first _:5a1f0;
  rdf:rest rdf:nil .

_:5a1f0 a owl:Restriction;
  owl:onProperty <http://purl.obolibrary.org/obo/has_confidence_level>;
  owl:onClass <http://purl.obolibrary.org/obo/CIO_0000028>;
  owl:maxQualifiedCardinality "1"^^xsd:nonNegativeInteger .

_:5a220 rdf:first _:5a210;
  rdf:rest rdf:nil .

_:5a210 a owl:Class;
  owl:intersectionOf _:5a240 .

_:5a240 rdf:first _:5a230;
  rdf:rest _:5a260 .

_:5a230 a owl:Restriction;
  owl:onProperty <http://purl.obolibrary.org/obo/has_evidence_concordance>;
  owl:allValuesFrom <http://purl.obolibrary.org/obo/CIO_0000043> .

_:5a260 rdf:first _:5a250;
  rdf:rest _:5a280 .

_:5a250 a owl:Restriction;
  owl:onProperty <http://purl.obolibrary.org/obo/has_confidence_element>;
  owl:onClass <http://purl.obolibrary.org/obo/CIO_0000040>;
  owl:minQualifiedCardinality "2"^^xsd:nonNegativeInteger .

_:5a280 rdf:first _:5a270;
  rdf:rest _:5a2a0 .

_:5a270 a owl:Restriction;
  owl:onProperty <http://purl.obolibrary.org/obo/has_confidence_level>;
  owl:onClass <http://purl.obolibrary.org/obo/CIO_0000028>;
  owl:minQualifiedCardinality "0"^^xsd:nonNegativeInteger .

_:5a2a0 rdf:first _:5a290;
  rdf:rest _:5a2c0 .

_:5a290 a owl:Restriction;
  owl:onProperty <http://purl.obolibrary.org/obo/has_evidence_type_concordance>;
  owl:onClass <http://purl.obolibrary.org/obo/CIO_0000041>;
  owl:qualifiedCardinality "1"^^xsd:nonNegativeInteger .

_:5a2c0 rdf:first _:5a2b0;
  rdf:rest _:5a2e0 .

_:5a2b0 a owl:Restriction;
  owl:onProperty <http://purl.obolibrary.org/obo/has_confidence_element>;
  owl:onClass <http://purl.obolibrary.org/obo/CIO_0000040>;
  owl:maxQualifiedCardinality "3"^^xsd:nonNegativeInteger .

_:5a2e0 rdf:first _:5a2d0;
  rdf:rest rdf:nil .

_:5a2d0 a owl:Restriction;
  owl:onProperty <http://purl.obolibrary.org/obo/has_confidence_level>;
  owl:onClass <http://purl.obolibrary.org/obo/CIO_0000028>;
  owl:maxQualifiedCardinality "1"^^xsd:nonNegativeInteger .

_:5a2f0 a owl:Class;
  owl:intersectionOf _:5a310 .

_:5a310 rdf:first _:5a300;
  rdf:rest _:5a330 .

_:5a300 a owl:Restriction;
  owl:onProperty <http://purl.obolibrary.org/obo/has_confidence_element>;
  owl:onClass <http://purl.obolibrary.org/obo/CIO_0000040>;
  owl:minQualifiedCardinality "1"^^xsd:nonNegativeInteger .

_:5a330 rdf:first _:5a320;
  rdf:rest _:5a350 .

_:5a320 a owl:Restriction;
  owl:onProperty <http://purl.obolibrary.org/obo/has_confidence_level>;
  owl:onClass <http://purl.obolibrary.org/obo/CIO_0000028>;
  owl:minQualifiedCardinality "0"^^xsd:nonNegativeInteger .

_:5a350 rdf:first _:5a340;
  rdf:rest _:5a370 .

_:5a340 a owl:Restriction;
  owl:onProperty <http://purl.obolibrary.org/obo/has_evidence_type_concordance>;
  owl:onClass <http://purl.obolibrary.org/obo/CIO_0000041>;
  owl:minQualifiedCardinality "0"^^xsd:nonNegativeInteger .

_:5a370 rdf:first _:5a360;
  rdf:rest _:5a390 .

_:5a360 a owl:Restriction;
  owl:onProperty <http://purl.obolibrary.org/obo/has_evidence_concordance>;
  owl:onClass <http://purl.obolibrary.org/obo/CIO_0000032>;
  owl:qualifiedCardinality "1"^^xsd:nonNegativeInteger .

_:5a390 rdf:first _:5a380;
  rdf:rest _:5a3b0 .

_:5a380 a owl:Restriction;
  owl:onProperty <http://purl.obolibrary.org/obo/has_confidence_element>;
  owl:onClass <http://purl.obolibrary.org/obo/CIO_0000040>;
  owl:maxQualifiedCardinality "3"^^xsd:nonNegativeInteger .

_:5a3b0 rdf:first _:5a3a0;
  rdf:rest _:5a3d0 .

_:5a3a0 a owl:Restriction;
  owl:onProperty <http://purl.obolibrary.org/obo/has_confidence_level>;
  owl:onClass <http://purl.obolibrary.org/obo/CIO_0000028>;
  owl:maxQualifiedCardinality "1"^^xsd:nonNegativeInteger .

_:5a3d0 rdf:first _:5a3c0;
  rdf:rest rdf:nil .

_:5a3c0 a owl:Restriction;
  owl:onProperty <http://purl.obolibrary.org/obo/has_evidence_type_concordance>;
  owl:onClass <http://purl.obolibrary.org/obo/CIO_0000041>;
  owl:maxQualifiedCardinality "1"^^xsd:nonNegativeInteger .

_:5a3e0 a owl:Restriction;
  owl:onProperty <http://purl.obolibrary.org/obo/has_confidence_level>;
  owl:onClass <http://purl.obolibrary.org/obo/CIO_0000028>;
  owl:maxQualifiedCardinality "1"^^xsd:nonNegativeInteger .

_:5a3f0 a owl:Restriction;
  owl:onProperty <http://purl.obolibrary.org/obo/has_confidence_element>;
  owl:onClass <http://purl.obolibrary.org/obo/CIO_0000040>;
  owl:minQualifiedCardinality "1"^^xsd:nonNegativeInteger .

_:5a400 a owl:Restriction;
  owl:onProperty <http://purl.obolibrary.org/obo/has_evidence_type_concordance>;
  owl:onClass <http://purl.obolibrary.org/obo/CIO_0000041>;
  owl:maxQualifiedCardinality "1"^^xsd:nonNegativeInteger .

_:5a410 a owl:Restriction;
  owl:onProperty <http://purl.obolibrary.org/obo/has_evidence_type_concordance>;
  owl:onClass <http://purl.obolibrary.org/obo/CIO_0000041>;
  owl:minQualifiedCardinality "0"^^xsd:nonNegativeInteger .

_:5a420 a owl:Restriction;
  owl:onProperty <http://purl.obolibrary.org/obo/has_evidence_concordance>;
  owl:onClass <http://purl.obolibrary.org/obo/CIO_0000032>;
  owl:qualifiedCardinality "1"^^xsd:nonNegativeInteger .

_:5a430 a owl:Restriction;
  owl:onProperty <http://purl.obolibrary.org/obo/has_confidence_element>;
  owl:onClass <http://purl.obolibrary.org/obo/CIO_0000040>;
  owl:maxQualifiedCardinality "3"^^xsd:nonNegativeInteger .

_:5a440 a owl:Restriction;
  owl:onProperty <http://purl.obolibrary.org/obo/has_confidence_level>;
  owl:onClass <http://purl.obolibrary.org/obo/CIO_0000028>;
  owl:minQualifiedCardinality "0"^^xsd:nonNegativeInteger .

_:5a450 a owl:Axiom;
  owl:annotatedTarget "A statement providing information about the confidence in an assertion, meaning, an information about the level of certainty that an assertion is correct.";
  <http://www.geneontology.org/formats/oboInOwl#hasDbXref> "Bgee:fbb";
  owl:annotatedSource <http://purl.obolibrary.org/obo/CIO_0000000>;
  owl:annotatedProperty <http://purl.obolibrary.org/obo/IAO_0000115> .

<http://purl.obolibrary.org/obo/CIO_0000001> a owl:Class;
  rdfs:label "confidence statement from single evidence";
  owl:equivalentClass _:5a460;
  rdfs:subClassOf <http://purl.obolibrary.org/obo/CIO_0000000>, _:5a4c0, _:5a4d0;
  owl:disjointWith <http://purl.obolibrary.org/obo/CIO_0000002>;
  <http://purl.obolibrary.org/obo/IAO_0000115> "A confidence information statement defined from a single evidence.";
  <http://www.geneontology.org/formats/oboInOwl#id> "CIO:0000001" .

_:5a460 a owl:Class;
  owl:intersectionOf _:5a470 .

_:5a470 rdf:first <http://purl.obolibrary.org/obo/CIO_0000000>;
  rdf:rest _:5a490 .

_:5a490 rdf:first _:5a480;
  rdf:rest _:5a4b0 .

_:5a480 a owl:Restriction;
  owl:onProperty <http://purl.obolibrary.org/obo/has_evidence_concordance>;
  owl:allValuesFrom <http://purl.obolibrary.org/obo/CIO_0000042> .

_:5a4b0 rdf:first _:5a4a0;
  rdf:rest rdf:nil .

_:5a4a0 a owl:Restriction;
  owl:onProperty <http://purl.obolibrary.org/obo/has_evidence_type_concordance>;
  owl:onClass <http://purl.obolibrary.org/obo/CIO_0000041>;
  owl:qualifiedCardinality "0"^^xsd:nonNegativeInteger .

_:5a4c0 a owl:Restriction;
  owl:onProperty <http://purl.obolibrary.org/obo/has_evidence_concordance>;
  owl:allValuesFrom <http://purl.obolibrary.org/obo/CIO_0000042> .

_:5a4d0 a owl:Restriction;
  owl:onProperty <http://purl.obolibrary.org/obo/has_evidence_type_concordance>;
  owl:onClass <http://purl.obolibrary.org/obo/CIO_0000041>;
  owl:qualifiedCardinality "0"^^xsd:nonNegativeInteger .

_:5a4e0 a owl:Axiom;
  owl:annotatedTarget "A confidence information statement defined from a single evidence.";
  <http://www.geneontology.org/formats/oboInOwl#hasDbXref> "Bgee:fbb";
  owl:annotatedSource <http://purl.obolibrary.org/obo/CIO_0000001>;
  owl:annotatedProperty <http://purl.obolibrary.org/obo/IAO_0000115> .

<http://purl.obolibrary.org/obo/CIO_0000002> a owl:Class;
  rdfs:label "confidence statement from multiple evidence lines";
  owl:equivalentClass _:5a4f0;
  rdfs:subClassOf <http://purl.obolibrary.org/obo/CIO_0000000>, _:5a550, _:5a560;
  <http://purl.obolibrary.org/obo/IAO_0000115> "A confidence information statement defined from a set of evidence lines.";
  <http://www.geneontology.org/formats/oboInOwl#id> "CIO:0000002" .

_:5a4f0 a owl:Class;
  owl:intersectionOf _:5a500 .

_:5a500 rdf:first <http://purl.obolibrary.org/obo/CIO_0000000>;
  rdf:rest _:5a520 .

_:5a520 rdf:first _:5a510;
  rdf:rest _:5a540 .

_:5a510 a owl:Restriction;
  owl:onProperty <http://purl.obolibrary.org/obo/has_evidence_concordance>;
  owl:allValuesFrom <http://purl.obolibrary.org/obo/CIO_0000043> .

_:5a540 rdf:first _:5a530;
  rdf:rest rdf:nil .

_:5a530 a owl:Restriction;
  owl:onProperty <http://purl.obolibrary.org/obo/has_evidence_type_concordance>;
  owl:onClass <http://purl.obolibrary.org/obo/CIO_0000041>;
  owl:qualifiedCardinality "1"^^xsd:nonNegativeInteger .

_:5a550 a owl:Restriction;
  owl:onProperty <http://purl.obolibrary.org/obo/has_evidence_type_concordance>;
  owl:onClass <http://purl.obolibrary.org/obo/CIO_0000041>;
  owl:qualifiedCardinality "1"^^xsd:nonNegativeInteger .

_:5a560 a owl:Restriction;
  owl:onProperty <http://purl.obolibrary.org/obo/has_evidence_concordance>;
  owl:allValuesFrom <http://purl.obolibrary.org/obo/CIO_0000043> .

_:5a570 a owl:Axiom;
  owl:annotatedTarget "A confidence information statement defined from a set of evidence lines.";
  <http://www.geneontology.org/formats/oboInOwl#hasDbXref> "Bgee:fbb";
  owl:annotatedSource <http://purl.obolibrary.org/obo/CIO_0000002>;
  owl:annotatedProperty <http://purl.obolibrary.org/obo/IAO_0000115> .

<http://purl.obolibrary.org/obo/CIO_0000003> a owl:Class;
  rdfs:label "high confidence from single evidence";
  owl:equivalentClass _:5a580;
  rdfs:subClassOf <http://purl.obolibrary.org/obo/CIO_0000001>, _:5a5c0;
  owl:disjointWith <http://purl.obolibrary.org/obo/CIO_0000004>, <http://purl.obolibrary.org/obo/CIO_0000005>,
    <http://purl.obolibrary.org/obo/CIO_0000039>;
  <http://purl.obolibrary.org/obo/IAO_0000115> "A confidence statement from single evidence related to assertions supported by a highly reliable evidence.";
  <http://www.geneontology.org/formats/oboInOwl#id> "CIO:0000003";
  <http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym> "gold" .

_:5a580 a owl:Class;
  owl:intersectionOf _:5a590 .

_:5a590 rdf:first <http://purl.obolibrary.org/obo/CIO_0000001>;
  rdf:rest _:5a5b0 .

_:5a5b0 rdf:first _:5a5a0;
  rdf:rest rdf:nil .

_:5a5a0 a owl:Restriction;
  owl:onProperty <http://purl.obolibrary.org/obo/has_confidence_level>;
  owl:allValuesFrom <http://purl.obolibrary.org/obo/CIO_0000029> .

_:5a5c0 a owl:Restriction;
  owl:onProperty <http://purl.obolibrary.org/obo/has_confidence_level>;
  owl:allValuesFrom <http://purl.obolibrary.org/obo/CIO_0000029> .

_:5a5d0 a owl:Axiom;
  owl:annotatedTarget "A confidence statement from single evidence related to assertions supported by a highly reliable evidence.";
  <http://www.geneontology.org/formats/oboInOwl#hasDbXref> "Bgee:fbb";
  owl:annotatedSource <http://purl.obolibrary.org/obo/CIO_0000003>;
  owl:annotatedProperty <http://purl.obolibrary.org/obo/IAO_0000115> .

_:5a5e0 a owl:Axiom;
  owl:annotatedTarget "gold";
  <http://www.geneontology.org/formats/oboInOwl#hasDbXref> "neXtProt";
  owl:annotatedSource <http://purl.obolibrary.org/obo/CIO_0000003>;
  owl:annotatedProperty <http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym> .

<http://purl.obolibrary.org/obo/CIO_0000004> a owl:Class;
  rdfs:label "medium confidence from single evidence";
  owl:equivalentClass _:5a5f0;
  rdfs:subClassOf <http://purl.obolibrary.org/obo/CIO_0000001>, _:5a630;
  owl:disjointWith <http://purl.obolibrary.org/obo/CIO_0000005>, <http://purl.obolibrary.org/obo/CIO_0000039>;
  <http://purl.obolibrary.org/obo/IAO_0000115> "A confidence statement from single evidence related to assertions supported by moderately trusted evidence.";
  <http://www.geneontology.org/formats/oboInOwl#id> "CIO:0000004";
  <http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym> "silver" .

_:5a5f0 a owl:Class;
  owl:intersectionOf _:5a600 .

_:5a600 rdf:first <http://purl.obolibrary.org/obo/CIO_0000001>;
  rdf:rest _:5a620 .

_:5a620 rdf:first _:5a610;
  rdf:rest rdf:nil .

_:5a610 a owl:Restriction;
  owl:onProperty <http://purl.obolibrary.org/obo/has_confidence_level>;
  owl:allValuesFrom <http://purl.obolibrary.org/obo/CIO_0000030> .

_:5a630 a owl:Restriction;
  owl:onProperty <http://purl.obolibrary.org/obo/has_confidence_level>;
  owl:allValuesFrom <http://purl.obolibrary.org/obo/CIO_0000030> .

_:5a640 a owl:Axiom;
  owl:annotatedTarget "A confidence statement from single evidence related to assertions supported by moderately trusted evidence.";
  <http://www.geneontology.org/formats/oboInOwl#hasDbXref> "Bgee:fbb";
  owl:annotatedSource <http://purl.obolibrary.org/obo/CIO_0000004>;
  owl:annotatedProperty <http://purl.obolibrary.org/obo/IAO_0000115> .

_:5a650 a owl:Axiom;
  <http://www.geneontology.org/formats/oboInOwl#hasDbXref> "neXtProt";
  owl:annotatedTarget "silver";
  owl:annotatedSource <http://purl.obolibrary.org/obo/CIO_0000004>;
  owl:annotatedProperty <http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym> .

<http://purl.obolibrary.org/obo/CIO_0000005> a owl:Class;
  rdfs:label "low confidence from single evidence";
  owl:equivalentClass _:5a660;
  rdfs:subClassOf <http://purl.obolibrary.org/obo/CIO_0000001>, _:5a6a0;
  owl:disjointWith <http://purl.obolibrary.org/obo/CIO_0000039>;
  <http://purl.obolibrary.org/obo/IAO_0000115> "A confidence statement from single evidence related to assertions supported by not-trusted evidence.";
  <http://www.geneontology.org/formats/oboInOwl#id> "CIO:0000005";
  <http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym> "bronze";
  <http://www.geneontology.org/formats/oboInOwl#inSubset> <http://purl.obolibrary.org/obo/cio/#bgee_not_trusted> .

_:5a660 a owl:Class;
  owl:intersectionOf _:5a670 .

_:5a670 rdf:first <http://purl.obolibrary.org/obo/CIO_0000001>;
  rdf:rest _:5a690 .

_:5a690 rdf:first _:5a680;
  rdf:rest rdf:nil .

_:5a680 a owl:Restriction;
  owl:onProperty <http://purl.obolibrary.org/obo/has_confidence_level>;
  owl:allValuesFrom <http://purl.obolibrary.org/obo/CIO_0000031> .

_:5a6a0 a owl:Restriction;
  owl:onProperty <http://purl.obolibrary.org/obo/has_confidence_level>;
  owl:allValuesFrom <http://purl.obolibrary.org/obo/CIO_0000031> .

_:5a6b0 a owl:Axiom;
  owl:annotatedTarget "A confidence statement from single evidence related to assertions supported by not-trusted evidence.";
  <http://www.geneontology.org/formats/oboInOwl#hasDbXref> "Bgee:fbb";
  owl:annotatedSource <http://purl.obolibrary.org/obo/CIO_0000005>;
  owl:annotatedProperty <http://purl.obolibrary.org/obo/IAO_0000115> .

_:5a6c0 a owl:Axiom;
  owl:annotatedTarget "bronze";
  <http://www.geneontology.org/formats/oboInOwl#hasDbXref> "neXtProt";
  owl:annotatedSource <http://purl.obolibrary.org/obo/CIO_0000005>;
  owl:annotatedProperty <http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym> .

<http://purl.obolibrary.org/obo/CIO_0000006> a owl:Class;
  rdfs:label "confidence statement from multiple evidence lines of same type";
  owl:equivalentClass _:5a6d0;
  rdfs:subClassOf <http://purl.obolibrary.org/obo/CIO_0000002>, _:5a710;
  owl:disjointWith <http://purl.obolibrary.org/obo/CIO_0000007>;
  <http://purl.obolibrary.org/obo/IAO_0000115> "A confidence statement from multiple evidence lines, all using a same experimental or computational type.";
  <http://www.geneontology.org/formats/oboInOwl#id> "CIO:0000006" .

_:5a6d0 a owl:Class;
  owl:intersectionOf _:5a6e0 .

_:5a6e0 rdf:first <http://purl.obolibrary.org/obo/CIO_0000002>;
  rdf:rest _:5a700 .

_:5a700 rdf:first _:5a6f0;
  rdf:rest rdf:nil .

_:5a6f0 a owl:Restriction;
  owl:onProperty <http://purl.obolibrary.org/obo/has_evidence_type_concordance>;
  owl:allValuesFrom <http://purl.obolibrary.org/obo/CIO_0000037> .

_:5a710 a owl:Restriction;
  owl:onProperty <http://purl.obolibrary.org/obo/has_evidence_type_concordance>;
  owl:allValuesFrom <http://purl.obolibrary.org/obo/CIO_0000037> .

_:5a720 a owl:Axiom;
  owl:annotatedTarget "A confidence statement from multiple evidence lines, all using a same experimental or computational type.";
  <http://www.geneontology.org/formats/oboInOwl#hasDbXref> "Bgee:fbb";
  owl:annotatedSource <http://purl.obolibrary.org/obo/CIO_0000006>;
  owl:annotatedProperty <http://purl.obolibrary.org/obo/IAO_0000115> .

<http://purl.obolibrary.org/obo/CIO_0000007> a owl:Class;
  rdfs:label "confidence statement from multiple evidence lines of multiple types";
  owl:equivalentClass _:5a730;
  rdfs:subClassOf <http://purl.obolibrary.org/obo/CIO_0000002>, _:5a770;
  <http://purl.obolibrary.org/obo/IAO_0000115> "A confidence statement from multiple evidence lines, of different experimental or computational types.";
  <http://www.geneontology.org/formats/oboInOwl#id> "CIO:0000007" .

_:5a730 a owl:Class;
  owl:intersectionOf _:5a740 .

_:5a740 rdf:first <http://purl.obolibrary.org/obo/CIO_0000002>;
  rdf:rest _:5a760 .

_:5a760 rdf:first _:5a750;
  rdf:rest rdf:nil .

_:5a750 a owl:Restriction;
  owl:onProperty <http://purl.obolibrary.org/obo/has_evidence_type_concordance>;
  owl:allValuesFrom <http://purl.obolibrary.org/obo/CIO_0000038> .

_:5a770 a owl:Restriction;
  owl:onProperty <http://purl.obolibrary.org/obo/has_evidence_type_concordance>;
  owl:allValuesFrom <http://purl.obolibrary.org/obo/CIO_0000038> .

_:5a780 a owl:Axiom;
  owl:annotatedTarget "A confidence statement from multiple evidence lines, of different experimental or computational types.";
  <http://www.geneontology.org/formats/oboInOwl#hasDbXref> "Bgee:fbb";
  owl:annotatedSource <http://purl.obolibrary.org/obo/CIO_0000007>;
  owl:annotatedProperty <http://purl.obolibrary.org/obo/IAO_0000115> .

<http://purl.obolibrary.org/obo/CIO_0000008> a owl:Class;
  rdfs:label "confidence statement from congruent evidence lines of multiple types";
  owl:equivalentClass _:5a790;
  rdfs:subClassOf <http://purl.obolibrary.org/obo/CIO_0000007>, _:5a7d0;
  owl:disjointWith <http://purl.obolibrary.org/obo/CIO_0000009>;
  <http://purl.obolibrary.org/obo/IAO_0000115> "A confidence statement from multiple evidence lines of multiple types, that are all congruent.";
  <http://www.geneontology.org/formats/oboInOwl#id> "CIO:0000008" .

_:5a790 a owl:Class;
  owl:intersectionOf _:5a7a0 .

_:5a7a0 rdf:first <http://purl.obolibrary.org/obo/CIO_0000007>;
  rdf:rest _:5a7c0 .

_:5a7c0 rdf:first _:5a7b0;
  rdf:rest rdf:nil .

_:5a7b0 a owl:Restriction;
  owl:onProperty <http://purl.obolibrary.org/obo/has_evidence_concordance>;
  owl:allValuesFrom <http://purl.obolibrary.org/obo/CIO_0000033> .

_:5a7d0 a owl:Restriction;
  owl:onProperty <http://purl.obolibrary.org/obo/has_evidence_concordance>;
  owl:allValuesFrom <http://purl.obolibrary.org/obo/CIO_0000033> .

_:5a7e0 a owl:Axiom;
  owl:annotatedTarget "A confidence statement from multiple evidence lines of multiple types, that are all congruent.";
  <http://www.geneontology.org/formats/oboInOwl#hasDbXref> "Bgee:fbb";
  owl:annotatedSource <http://purl.obolibrary.org/obo/CIO_0000008>;
  owl:annotatedProperty <http://purl.obolibrary.org/obo/IAO_0000115> .

<http://purl.obolibrary.org/obo/CIO_0000009> a owl:Class;
  rdfs:label "confidence statement from conflicting evidence lines of multiple types";
  owl:equivalentClass _:5a7f0;
  rdfs:subClassOf <http://purl.obolibrary.org/obo/CIO_0000007>, _:5a830;
  <http://purl.obolibrary.org/obo/IAO_0000115> "A confidence statement from multiple evidence lines of multiple types, some of which being contradictory.";
  <http://www.geneontology.org/formats/oboInOwl#id> "CIO:0000009" .

_:5a7f0 a owl:Class;
  owl:intersectionOf _:5a800 .

_:5a800 rdf:first <http://purl.obolibrary.org/obo/CIO_0000007>;
  rdf:rest _:5a820 .

_:5a820 rdf:first _:5a810;
  rdf:rest rdf:nil .

_:5a810 a owl:Restriction;
  owl:onProperty <http://purl.obolibrary.org/obo/has_evidence_concordance>;
  owl:allValuesFrom <http://purl.obolibrary.org/obo/CIO_0000034> .

_:5a830 a owl:Restriction;
  owl:onProperty <http://purl.obolibrary.org/obo/has_evidence_concordance>;
  owl:allValuesFrom <http://purl.obolibrary.org/obo/CIO_0000034> .

_:5a840 a owl:Axiom;
  owl:annotatedTarget "A confidence statement from multiple evidence lines of multiple types, some of which being contradictory.";
  <http://www.geneontology.org/formats/oboInOwl#hasDbXref> "Bgee:fbb";
  owl:annotatedSource <http://purl.obolibrary.org/obo/CIO_0000009>;
  owl:annotatedProperty <http://purl.obolibrary.org/obo/IAO_0000115> .

<http://purl.obolibrary.org/obo/CIO_0000010> a owl:Class;
  rdfs:label "confidence statement from strongly conflicting evidence lines of multiple types";
  owl:equivalentClass _:5a850;
  rdfs:subClassOf <http://purl.obolibrary.org/obo/CIO_0000009>, _:5a8b0, _:5a8c0;
  owl:disjointWith <http://purl.obolibrary.org/obo/CIO_0000011>;
  <http://purl.obolibrary.org/obo/IAO_0000115> "A confidence statement from conflicting evidence lines of multiple types, where evidence lines are in strong contradiction, meaning that the supporting evidence lines yield different conclusion, several of them being equally likely to be true.";
  <http://www.geneontology.org/formats/oboInOwl#id> "CIO:0000010";
  <http://www.geneontology.org/formats/oboInOwl#inSubset> <http://purl.obolibrary.org/obo/cio/#bgee_not_trusted> .

_:5a850 a owl:Class;
  owl:intersectionOf _:5a860 .

_:5a860 rdf:first <http://purl.obolibrary.org/obo/CIO_0000009>;
  rdf:rest _:5a880 .

_:5a880 rdf:first _:5a870;
  rdf:rest _:5a8a0 .

_:5a870 a owl:Restriction;
  owl:onProperty <http://purl.obolibrary.org/obo/has_evidence_concordance>;
  owl:allValuesFrom <http://purl.obolibrary.org/obo/CIO_0000035> .

_:5a8a0 rdf:first _:5a890;
  rdf:rest rdf:nil .

_:5a890 a owl:Restriction;
  owl:onProperty <http://purl.obolibrary.org/obo/has_confidence_level>;
  owl:onClass <http://purl.obolibrary.org/obo/CIO_0000028>;
  owl:qualifiedCardinality "0"^^xsd:nonNegativeInteger .

_:5a8b0 a owl:Restriction;
  owl:onProperty <http://purl.obolibrary.org/obo/has_evidence_concordance>;
  owl:allValuesFrom <http://purl.obolibrary.org/obo/CIO_0000035> .

_:5a8c0 a owl:Restriction;
  owl:onProperty <http://purl.obolibrary.org/obo/has_confidence_level>;
  owl:onClass <http://purl.obolibrary.org/obo/CIO_0000028>;
  owl:qualifiedCardinality "0"^^xsd:nonNegativeInteger .

_:5a8d0 a owl:Axiom;
  owl:annotatedTarget "A confidence statement from conflicting evidence lines of multiple types, where evidence lines are in strong contradiction, meaning that the supporting evidence lines yield different conclusion, several of them being equally likely to be true.";
  <http://www.geneontology.org/formats/oboInOwl#hasDbXref> "Bgee:fbb";
  owl:annotatedSource <http://purl.obolibrary.org/obo/CIO_0000010>;
  owl:annotatedProperty <http://purl.obolibrary.org/obo/IAO_0000115> .

<http://purl.obolibrary.org/obo/CIO_0000011> a owl:Class;
  rdfs:label "confidence statement from weakly conflicting evidence lines of multiple types";
  owl:equivalentClass _:5a8e0;
  rdfs:subClassOf <http://purl.obolibrary.org/obo/CIO_0000009>, _:5a920;
  <http://purl.obolibrary.org/obo/IAO_0000115> "A confidence statement from conflicting evidence lines of multiple types, where evidence lines are in weak contradiction, meaning that the overall supported assertion is believed to be true, but a subset of less-reliable evidence lines are in contradiction.";
  <http://www.geneontology.org/formats/oboInOwl#id> "CIO:0000011" .

_:5a8e0 a owl:Class;
  owl:intersectionOf _:5a8f0 .

_:5a8f0 rdf:first <http://purl.obolibrary.org/obo/CIO_0000009>;
  rdf:rest _:5a910 .

_:5a910 rdf:first _:5a900;
  rdf:rest rdf:nil .

_:5a900 a owl:Restriction;
  owl:onProperty <http://purl.obolibrary.org/obo/has_evidence_concordance>;
  owl:allValuesFrom <http://purl.obolibrary.org/obo/CIO_0000036> .

_:5a920 a owl:Restriction;
  owl:onProperty <http://purl.obolibrary.org/obo/has_evidence_concordance>;
  owl:allValuesFrom <http://purl.obolibrary.org/obo/CIO_0000036> .

_:5a930 a owl:Axiom;
  owl:annotatedTarget "A confidence statement from conflicting evidence lines of multiple types, where evidence lines are in weak contradiction, meaning that the overall supported assertion is believed to be true, but a subset of less-reliable evidence lines are in contradiction.";
  <http://www.geneontology.org/formats/oboInOwl#hasDbXref> "Bgee:fbb";
  owl:annotatedSource <http://purl.obolibrary.org/obo/CIO_0000011>;
  owl:annotatedProperty <http://purl.obolibrary.org/obo/IAO_0000115> .

<http://purl.obolibrary.org/obo/CIO_0000012> a owl:Class;
  rdfs:label "confidence statement from congruent evidence lines of multiple types, overall confidence high";
  owl:equivalentClass _:5a940;
  rdfs:subClassOf <http://purl.obolibrary.org/obo/CIO_0000008>, _:5a980;
  owl:disjointWith <http://purl.obolibrary.org/obo/CIO_0000013>, <http://purl.obolibrary.org/obo/CIO_0000014>;
  <http://purl.obolibrary.org/obo/IAO_0000115> "A confidence statement from congruent evidence lines of multiple types, of an overall high confidence level.";
  <http://www.geneontology.org/formats/oboInOwl#id> "CIO:0000012";
  rdfs:comment "Different strategies can be used to define the overall confidence level: for instance, it could be defined based on the confidence level of the most trusted evidence, from the set of evidence lines supporting the assertion; or, it could be defined based on the number of evidence lines supporting the assertion (e.g., 10 congruent low-confidence evidence lines could allow to have an overall high confidence in an assertion). It is the responsibility of annotation teams to define and communicate the parameters, pertinent to their field, allowing to produce overall confidence levels." .

_:5a940 a owl:Class;
  owl:intersectionOf _:5a950 .

_:5a950 rdf:first <http://purl.obolibrary.org/obo/CIO_0000008>;
  rdf:rest _:5a970 .

_:5a970 rdf:first _:5a960;
  rdf:rest rdf:nil .

_:5a960 a owl:Restriction;
  owl:onProperty <http://purl.obolibrary.org/obo/has_confidence_level>;
  owl:allValuesFrom <http://purl.obolibrary.org/obo/CIO_0000029> .

_:5a980 a owl:Restriction;
  owl:onProperty <http://purl.obolibrary.org/obo/has_confidence_level>;
  owl:allValuesFrom <http://purl.obolibrary.org/obo/CIO_0000029> .

_:5a990 a owl:Axiom;
  owl:annotatedTarget "A confidence statement from congruent evidence lines of multiple types, of an overall high confidence level.";
  <http://www.geneontology.org/formats/oboInOwl#hasDbXref> "Bgee:fbb";
  owl:annotatedSource <http://purl.obolibrary.org/obo/CIO_0000012>;
  owl:annotatedProperty <http://purl.obolibrary.org/obo/IAO_0000115> .

<http://purl.obolibrary.org/obo/CIO_0000013> a owl:Class;
  rdfs:label "confidence statement from congruent evidence lines of multiple types, overall confidence medium";
  owl:equivalentClass _:5a9a0;
  rdfs:subClassOf <http://purl.obolibrary.org/obo/CIO_0000008>, _:5a9e0;
  owl:disjointWith <http://purl.obolibrary.org/obo/CIO_0000014>;
  <http://purl.obolibrary.org/obo/IAO_0000115> "A confidence statement from congruent evidence lines of multiple types, of an overall moderately trusted confidence level.";
  <http://www.geneontology.org/formats/oboInOwl#id> "CIO:0000013";
  rdfs:comment "Different strategies can be used to define the overall confidence level: for instance, it could be defined based on the confidence level of the most trusted evidence, from the set of evidence lines supporting the assertion; or, it could be defined based on the number of evidence lines supporting the assertion (e.g., 10 congruent low-confidence evidence lines could allow to have an overall high confidence in an assertion). It is the responsibility of annotation teams to define and communicate the parameters, pertinent to their field, allowing to produce overall confidence levels." .

_:5a9a0 a owl:Class;
  owl:intersectionOf _:5a9b0 .

_:5a9b0 rdf:first <http://purl.obolibrary.org/obo/CIO_0000008>;
  rdf:rest _:5a9d0 .

_:5a9d0 rdf:first _:5a9c0;
  rdf:rest rdf:nil .

_:5a9c0 a owl:Restriction;
  owl:onProperty <http://purl.obolibrary.org/obo/has_confidence_level>;
  owl:allValuesFrom <http://purl.obolibrary.org/obo/CIO_0000030> .

_:5a9e0 a owl:Restriction;
  owl:onProperty <http://purl.obolibrary.org/obo/has_confidence_level>;
  owl:allValuesFrom <http://purl.obolibrary.org/obo/CIO_0000030> .

_:5a9f0 a owl:Axiom;
  owl:annotatedTarget "A confidence statement from congruent evidence lines of multiple types, of an overall moderately trusted confidence level.";
  <http://www.geneontology.org/formats/oboInOwl#hasDbXref> "Bgee:fbb";
  owl:annotatedSource <http://purl.obolibrary.org/obo/CIO_0000013>;
  owl:annotatedProperty <http://purl.obolibrary.org/obo/IAO_0000115> .

<http://purl.obolibrary.org/obo/CIO_0000014> a owl:Class;
  rdfs:label "confidence statement from congruent evidence lines of multiple types, overall confidence low";
  owl:equivalentClass _:5aa00;
  rdfs:subClassOf <http://purl.obolibrary.org/obo/CIO_0000008>, _:5aa40;
  <http://purl.obolibrary.org/obo/IAO_0000115> "A confidence statement from congruent evidence lines of multiple types, of an overall not-trusted confidence level.";
  <http://www.geneontology.org/formats/oboInOwl#id> "CIO:0000014";
  rdfs:comment "Different strategies can be used to define the overall confidence level: for instance, it could be defined based on the confidence level of the most trusted evidence, from the set of evidence lines supporting the assertion; or, it could be defined based on the number of evidence lines supporting the assertion (e.g., 10 congruent low-confidence evidence lines could allow to have an overall high confidence in an assertion). It is the responsibility of annotation teams to define and communicate the parameters, pertinent to their field, allowing to produce overall confidence levels." .

_:5aa00 a owl:Class;
  owl:intersectionOf _:5aa10 .

_:5aa10 rdf:first <http://purl.obolibrary.org/obo/CIO_0000008>;
  rdf:rest _:5aa30 .

_:5aa30 rdf:first _:5aa20;
  rdf:rest rdf:nil .

_:5aa20 a owl:Restriction;
  owl:onProperty <http://purl.obolibrary.org/obo/has_confidence_level>;
  owl:allValuesFrom <http://purl.obolibrary.org/obo/CIO_0000031> .

_:5aa40 a owl:Restriction;
  owl:onProperty <http://purl.obolibrary.org/obo/has_confidence_level>;
  owl:allValuesFrom <http://purl.obolibrary.org/obo/CIO_0000031> .

_:5aa50 a owl:Axiom;
  owl:annotatedTarget "A confidence statement from congruent evidence lines of multiple types, of an overall not-trusted confidence level.";
  <http://www.geneontology.org/formats/oboInOwl#hasDbXref> "Bgee:fbb";
  owl:annotatedSource <http://purl.obolibrary.org/obo/CIO_0000014>;
  owl:annotatedProperty <http://purl.obolibrary.org/obo/IAO_0000115> .

<http://purl.obolibrary.org/obo/CIO_0000015> a owl:Class;
  rdfs:label "confidence statement from conflicting evidence lines of same type";
  owl:equivalentClass _:5aa60;
  rdfs:subClassOf <http://purl.obolibrary.org/obo/CIO_0000006>, _:5aaa0;
  owl:disjointWith <http://purl.obolibrary.org/obo/CIO_0000016>;
  <http://www.geneontology.org/formats/oboInOwl#id> "CIO:0000015";
  <http://purl.obolibrary.org/obo/IAO_0000115> "Confidence statement from multiple evidence lines of same type, some of which being contradictory." .

_:5aa60 a owl:Class;
  owl:intersectionOf _:5aa70 .

_:5aa70 rdf:first <http://purl.obolibrary.org/obo/CIO_0000006>;
  rdf:rest _:5aa90 .

_:5aa90 rdf:first _:5aa80;
  rdf:rest rdf:nil .

_:5aa80 a owl:Restriction;
  owl:onProperty <http://purl.obolibrary.org/obo/has_evidence_concordance>;
  owl:allValuesFrom <http://purl.obolibrary.org/obo/CIO_0000034> .

_:5aaa0 a owl:Restriction;
  owl:onProperty <http://purl.obolibrary.org/obo/has_evidence_concordance>;
  owl:allValuesFrom <http://purl.obolibrary.org/obo/CIO_0000034> .

_:5aab0 a owl:Axiom;
  <http://www.geneontology.org/formats/oboInOwl#hasDbXref> "Bgee:fbb";
  owl:annotatedTarget "Confidence statement from multiple evidence lines of same type, some of which being contradictory.";
  owl:annotatedSource <http://purl.obolibrary.org/obo/CIO_0000015>;
  owl:annotatedProperty <http://purl.obolibrary.org/obo/IAO_0000115> .

<http://purl.obolibrary.org/obo/CIO_0000016> a owl:Class;
  rdfs:label "confidence statement from congruent evidence lines of same type";
  owl:equivalentClass _:5aac0;
  rdfs:subClassOf <http://purl.obolibrary.org/obo/CIO_0000006>, _:5ab00;
  <http://www.geneontology.org/formats/oboInOwl#id> "CIO:0000016";
  <http://purl.obolibrary.org/obo/IAO_0000115> "Confidence statement from multiple evidence lines of same type, that are all congruent." .

_:5aac0 a owl:Class;
  owl:intersectionOf _:5aad0 .

_:5aad0 rdf:first <http://purl.obolibrary.org/obo/CIO_0000006>;
  rdf:rest _:5aaf0 .

_:5aaf0 rdf:first _:5aae0;
  rdf:rest rdf:nil .

_:5aae0 a owl:Restriction;
  owl:onProperty <http://purl.obolibrary.org/obo/has_evidence_concordance>;
  owl:allValuesFrom <http://purl.obolibrary.org/obo/CIO_0000033> .

_:5ab00 a owl:Restriction;
  owl:onProperty <http://purl.obolibrary.org/obo/has_evidence_concordance>;
  owl:allValuesFrom <http://purl.obolibrary.org/obo/CIO_0000033> .

_:5ab10 a owl:Axiom;
  <http://www.geneontology.org/formats/oboInOwl#hasDbXref> "Bgee:fbb";
  owl:annotatedTarget "Confidence statement from multiple evidence lines of same type, that are all congruent.";
  owl:annotatedSource <http://purl.obolibrary.org/obo/CIO_0000016>;
  owl:annotatedProperty <http://purl.obolibrary.org/obo/IAO_0000115> .

<http://purl.obolibrary.org/obo/CIO_0000017> a owl:Class;
  rdfs:label "confidence statement from congruent evidence lines of same type, overall confidence high";
  owl:equivalentClass _:5ab20;
  rdfs:subClassOf <http://purl.obolibrary.org/obo/CIO_0000016>, _:5ab60;
  owl:disjointWith <http://purl.obolibrary.org/obo/CIO_0000018>, <http://purl.obolibrary.org/obo/CIO_0000019>;
  <http://purl.obolibrary.org/obo/IAO_0000115> "A confidence statement from congruent evidence lines of same type, of an overall high confidence level.";
  <http://www.geneontology.org/formats/oboInOwl#id> "CIO:0000017";
  rdfs:comment "Different strategies can be used to define the overall confidence level: for instance, it could be defined based on the confidence level of the most trusted evidence, from the set of evidence lines supporting the assertion; or, it could be defined based on the number of evidence lines supporting the assertion (e.g., 10 congruent low-confidence evidence lines could allow to have an overall high confidence in an assertion). It is the responsibility of annotation teams to define and communicate the parameters, pertinent to their field, allowing to produce overall confidence levels." .

_:5ab20 a owl:Class;
  owl:intersectionOf _:5ab30 .

_:5ab30 rdf:first <http://purl.obolibrary.org/obo/CIO_0000016>;
  rdf:rest _:5ab50 .

_:5ab50 rdf:first _:5ab40;
  rdf:rest rdf:nil .

_:5ab40 a owl:Restriction;
  owl:onProperty <http://purl.obolibrary.org/obo/has_confidence_level>;
  owl:allValuesFrom <http://purl.obolibrary.org/obo/CIO_0000029> .

_:5ab60 a owl:Restriction;
  owl:onProperty <http://purl.obolibrary.org/obo/has_confidence_level>;
  owl:allValuesFrom <http://purl.obolibrary.org/obo/CIO_0000029> .

_:5ab70 a owl:Axiom;
  owl:annotatedTarget "A confidence statement from congruent evidence lines of same type, of an overall high confidence level.";
  <http://www.geneontology.org/formats/oboInOwl#hasDbXref> "Bgee:fbb";
  owl:annotatedSource <http://purl.obolibrary.org/obo/CIO_0000017>;
  owl:annotatedProperty <http://purl.obolibrary.org/obo/IAO_0000115> .

<http://purl.obolibrary.org/obo/CIO_0000018> a owl:Class;
  rdfs:label "confidence statement from congruent evidence lines of same type, overall confidence low";
  owl:equivalentClass _:5ab80;
  rdfs:subClassOf <http://purl.obolibrary.org/obo/CIO_0000016>, _:5abc0;
  owl:disjointWith <http://purl.obolibrary.org/obo/CIO_0000019>;
  <http://purl.obolibrary.org/obo/IAO_0000115> "A confidence statement from congruent evidence lines of same type, of an overall not-trusted confidence level.";
  <http://www.geneontology.org/formats/oboInOwl#id> "CIO:0000018";
  rdfs:comment "Different strategies can be used to define the overall confidence level: for instance, it could be defined based on the confidence level of the most trusted evidence, from the set of evidence lines supporting the assertion; or, it could be defined based on the number of evidence lines supporting the assertion (e.g., 10 congruent low-confidence evidence lines could allow to have an overall high confidence in an assertion). It is the responsibility of annotation teams to define and communicate the parameters, pertinent to their field, allowing to produce overall confidence levels." .

_:5ab80 a owl:Class;
  owl:intersectionOf _:5ab90 .

_:5ab90 rdf:first <http://purl.obolibrary.org/obo/CIO_0000016>;
  rdf:rest _:5abb0 .

_:5abb0 rdf:first _:5aba0;
  rdf:rest rdf:nil .

_:5aba0 a owl:Restriction;
  owl:onProperty <http://purl.obolibrary.org/obo/has_confidence_level>;
  owl:allValuesFrom <http://purl.obolibrary.org/obo/CIO_0000031> .

_:5abc0 a owl:Restriction;
  owl:onProperty <http://purl.obolibrary.org/obo/has_confidence_level>;
  owl:allValuesFrom <http://purl.obolibrary.org/obo/CIO_0000031> .

_:5abd0 a owl:Axiom;
  owl:annotatedTarget "A confidence statement from congruent evidence lines of same type, of an overall not-trusted confidence level.";
  <http://www.geneontology.org/formats/oboInOwl#hasDbXref> "Bgee:fbb";
  owl:annotatedSource <http://purl.obolibrary.org/obo/CIO_0000018>;
  owl:annotatedProperty <http://purl.obolibrary.org/obo/IAO_0000115> .

<http://purl.obolibrary.org/obo/CIO_0000019> a owl:Class;
  rdfs:label "confidence statement from congruent evidence lines of same type, overall confidence medium";
  owl:equivalentClass _:5abe0;
  rdfs:subClassOf <http://purl.obolibrary.org/obo/CIO_0000016>, _:5ac20;
  <http://purl.obolibrary.org/obo/IAO_0000115> "A confidence statement from congruent evidence lines of same type, of an overall moderately trusted confidence level.";
  <http://www.geneontology.org/formats/oboInOwl#id> "CIO:0000019";
  rdfs:comment "Different strategies can be used to define the overall confidence level: for instance, it could be defined based on the confidence level of the most trusted evidence, from the set of evidence lines supporting the assertion; or, it could be defined based on the number of evidence lines supporting the assertion (e.g., 10 congruent low-confidence evidence lines could allow to have an overall high confidence in an assertion). It is the responsibility of annotation teams to define and communicate the parameters, pertinent to their field, allowing to produce overall confidence levels." .

_:5abe0 a owl:Class;
  owl:intersectionOf _:5abf0 .

_:5abf0 rdf:first <http://purl.obolibrary.org/obo/CIO_0000016>;
  rdf:rest _:5ac10 .

_:5ac10 rdf:first _:5ac00;
  rdf:rest rdf:nil .

_:5ac00 a owl:Restriction;
  owl:onProperty <http://purl.obolibrary.org/obo/has_confidence_level>;
  owl:allValuesFrom <http://purl.obolibrary.org/obo/CIO_0000030> .

_:5ac20 a owl:Restriction;
  owl:onProperty <http://purl.obolibrary.org/obo/has_confidence_level>;
  owl:allValuesFrom <http://purl.obolibrary.org/obo/CIO_0000030> .

_:5ac30 a owl:Axiom;
  owl:annotatedTarget "A confidence statement from congruent evidence lines of same type, of an overall moderately trusted confidence level.";
  <http://www.geneontology.org/formats/oboInOwl#hasDbXref> "Bgee:fbb";
  owl:annotatedSource <http://purl.obolibrary.org/obo/CIO_0000019>;
  owl:annotatedProperty <http://purl.obolibrary.org/obo/IAO_0000115> .

<http://purl.obolibrary.org/obo/CIO_0000020> a owl:Class;
  rdfs:label "confidence statement from strongly conflicting evidence lines of same type";
  owl:equivalentClass _:5ac40;
  rdfs:subClassOf <http://purl.obolibrary.org/obo/CIO_0000015>, _:5aca0, _:5acb0;
  owl:disjointWith <http://purl.obolibrary.org/obo/CIO_0000021>;
  <http://www.geneontology.org/formats/oboInOwl#id> "CIO:0000020";
  <http://purl.obolibrary.org/obo/IAO_0000115> "Confidence statement from conflicting evidence lines of same type, where evidence lines are in strong contradiction, meaning that the supporting evidence lines yield different conclusion, several of them being equally likely to be true.";
  <http://www.geneontology.org/formats/oboInOwl#inSubset> <http://purl.obolibrary.org/obo/cio/#bgee_not_trusted> .

_:5ac40 a owl:Class;
  owl:intersectionOf _:5ac50 .

_:5ac50 rdf:first <http://purl.obolibrary.org/obo/CIO_0000015>;
  rdf:rest _:5ac70 .

_:5ac70 rdf:first _:5ac60;
  rdf:rest _:5ac90 .

_:5ac60 a owl:Restriction;
  owl:onProperty <http://purl.obolibrary.org/obo/has_evidence_concordance>;
  owl:allValuesFrom <http://purl.obolibrary.org/obo/CIO_0000035> .

_:5ac90 rdf:first _:5ac80;
  rdf:rest rdf:nil .

_:5ac80 a owl:Restriction;
  owl:onProperty <http://purl.obolibrary.org/obo/has_confidence_level>;
  owl:onClass <http://purl.obolibrary.org/obo/CIO_0000028>;
  owl:qualifiedCardinality "0"^^xsd:nonNegativeInteger .

_:5aca0 a owl:Restriction;
  owl:onProperty <http://purl.obolibrary.org/obo/has_evidence_concordance>;
  owl:allValuesFrom <http://purl.obolibrary.org/obo/CIO_0000035> .

_:5acb0 a owl:Restriction;
  owl:onProperty <http://purl.obolibrary.org/obo/has_confidence_level>;
  owl:onClass <http://purl.obolibrary.org/obo/CIO_0000028>;
  owl:qualifiedCardinality "0"^^xsd:nonNegativeInteger .

_:5acc0 a owl:Axiom;
  <http://www.geneontology.org/formats/oboInOwl#hasDbXref> "Bgee:fbb";
  owl:annotatedTarget "Confidence statement from conflicting evidence lines of same type, where evidence lines are in strong contradiction, meaning that the supporting evidence lines yield different conclusion, several of them being equally likely to be true.";
  owl:annotatedSource <http://purl.obolibrary.org/obo/CIO_0000020>;
  owl:annotatedProperty <http://purl.obolibrary.org/obo/IAO_0000115> .

<http://purl.obolibrary.org/obo/CIO_0000021> a owl:Class;
  rdfs:label "confidence statement from weakly conflicting evidence lines of same type";
  owl:equivalentClass _:5acd0;
  rdfs:subClassOf <http://purl.obolibrary.org/obo/CIO_0000015>, _:5ad10;
  <http://www.geneontology.org/formats/oboInOwl#id> "CIO:0000021";
  <http://purl.obolibrary.org/obo/IAO_0000115> "Confidence statement from conflicting evidence lines of same type, where evidence lines are in weak contradiction, meaning that the overall supported assertion is believed to be true, but a subset of less-reliable evidence lines are in contradiction." .

_:5acd0 a owl:Class;
  owl:intersectionOf _:5ace0 .

_:5ace0 rdf:first <http://purl.obolibrary.org/obo/CIO_0000015>;
  rdf:rest _:5ad00 .

_:5ad00 rdf:first _:5acf0;
  rdf:rest rdf:nil .

_:5acf0 a owl:Restriction;
  owl:onProperty <http://purl.obolibrary.org/obo/has_evidence_concordance>;
  owl:allValuesFrom <http://purl.obolibrary.org/obo/CIO_0000036> .

_:5ad10 a owl:Restriction;
  owl:onProperty <http://purl.obolibrary.org/obo/has_evidence_concordance>;
  owl:allValuesFrom <http://purl.obolibrary.org/obo/CIO_0000036> .

_:5ad20 a owl:Axiom;
  <http://www.geneontology.org/formats/oboInOwl#hasDbXref> "Bgee:fbb";
  owl:annotatedTarget "Confidence statement from conflicting evidence lines of same type, where evidence lines are in weak contradiction, meaning that the overall supported assertion is believed to be true, but a subset of less-reliable evidence lines are in contradiction.";
  owl:annotatedSource <http://purl.obolibrary.org/obo/CIO_0000021>;
  owl:annotatedProperty <http://purl.obolibrary.org/obo/IAO_0000115> .

<http://purl.obolibrary.org/obo/CIO_0000022> a owl:Class;
  rdfs:label "confidence statement from weakly conflicting evidence lines of same type, overall confidence high";
  owl:equivalentClass _:5ad30;
  rdfs:subClassOf <http://purl.obolibrary.org/obo/CIO_0000021>, _:5ad70;
  owl:disjointWith <http://purl.obolibrary.org/obo/CIO_0000023>, <http://purl.obolibrary.org/obo/CIO_0000024>;
  <http://www.geneontology.org/formats/oboInOwl#id> "CIO:0000022";
  <http://purl.obolibrary.org/obo/IAO_0000115> "Confidence statement from weakly conflicting evidence lines of same type, of an overall high confidence level.";
  rdfs:comment "Different strategies can be used to define the overall confidence level: for instance, it could be defined based on the confidence level of the most trusted evidence, from the set of evidence lines supporting (not contradicting) the assertion; or, it could be defined based on the number of evidence lines supporting the assertion (e.g., 10 congruent low-confidence evidence lines could allow to have an overall high confidence in an assertion, even if contradicted by one other low-confidence evidence). It is the responsibility of annotation teams to define and communicate the parameters, pertinent to their field, allowing to produce overall confidence levels." .

_:5ad30 a owl:Class;
  owl:intersectionOf _:5ad40 .

_:5ad40 rdf:first <http://purl.obolibrary.org/obo/CIO_0000021>;
  rdf:rest _:5ad60 .

_:5ad60 rdf:first _:5ad50;
  rdf:rest rdf:nil .

_:5ad50 a owl:Restriction;
  owl:onProperty <http://purl.obolibrary.org/obo/has_confidence_level>;
  owl:allValuesFrom <http://purl.obolibrary.org/obo/CIO_0000029> .

_:5ad70 a owl:Restriction;
  owl:onProperty <http://purl.obolibrary.org/obo/has_confidence_level>;
  owl:allValuesFrom <http://purl.obolibrary.org/obo/CIO_0000029> .

_:5ad80 a owl:Axiom;
  <http://www.geneontology.org/formats/oboInOwl#hasDbXref> "Bgee:fbb";
  owl:annotatedTarget "Confidence statement from weakly conflicting evidence lines of same type, of an overall high confidence level.";
  owl:annotatedSource <http://purl.obolibrary.org/obo/CIO_0000022>;
  owl:annotatedProperty <http://purl.obolibrary.org/obo/IAO_0000115> .

<http://purl.obolibrary.org/obo/CIO_0000023> a owl:Class;
  rdfs:label "confidence statement from weakly conflicting evidence lines of same type, overall confidence low";
  owl:equivalentClass _:5ad90;
  rdfs:subClassOf <http://purl.obolibrary.org/obo/CIO_0000021>, _:5add0;
  owl:disjointWith <http://purl.obolibrary.org/obo/CIO_0000024>;
  <http://www.geneontology.org/formats/oboInOwl#id> "CIO:0000023";
  <http://purl.obolibrary.org/obo/IAO_0000115> "Confidence statement from weakly conflicting evidence lines of same type, of an overall not-trusted confidence level.";
  rdfs:comment "Different strategies can be used to define the overall confidence level: for instance, it could be defined based on the confidence level of the most trusted evidence, from the set of evidence lines supporting (not contradicting) the assertion; or, it could be defined based on the number of evidence lines supporting the assertion (e.g., 10 congruent low-confidence evidence lines could allow to have an overall high confidence in an assertion, even if contradicted by one other low-confidence evidence). It is the responsibility of annotation teams to define and communicate the parameters, pertinent to their field, allowing to produce overall confidence levels.";
  <http://www.geneontology.org/formats/oboInOwl#inSubset> <http://purl.obolibrary.org/obo/cio/#bgee_not_trusted> .

_:5ad90 a owl:Class;
  owl:intersectionOf _:5ada0 .

_:5ada0 rdf:first <http://purl.obolibrary.org/obo/CIO_0000021>;
  rdf:rest _:5adc0 .

_:5adc0 rdf:first _:5adb0;
  rdf:rest rdf:nil .

_:5adb0 a owl:Restriction;
  owl:onProperty <http://purl.obolibrary.org/obo/has_confidence_level>;
  owl:allValuesFrom <http://purl.obolibrary.org/obo/CIO_0000031> .

_:5add0 a owl:Restriction;
  owl:onProperty <http://purl.obolibrary.org/obo/has_confidence_level>;
  owl:allValuesFrom <http://purl.obolibrary.org/obo/CIO_0000031> .

_:5ade0 a owl:Axiom;
  <http://www.geneontology.org/formats/oboInOwl#hasDbXref> "Bgee:fbb";
  owl:annotatedTarget "Confidence statement from weakly conflicting evidence lines of same type, of an overall not-trusted confidence level.";
  owl:annotatedSource <http://purl.obolibrary.org/obo/CIO_0000023>;
  owl:annotatedProperty <http://purl.obolibrary.org/obo/IAO_0000115> .

<http://purl.obolibrary.org/obo/CIO_0000024> a owl:Class;
  rdfs:label "confidence statement from weakly conflicting evidence lines of same type, overall confidence medium";
  owl:equivalentClass _:5adf0;
  rdfs:subClassOf <http://purl.obolibrary.org/obo/CIO_0000021>, _:5ae30;
  <http://www.geneontology.org/formats/oboInOwl#id> "CIO:0000024";
  <http://purl.obolibrary.org/obo/IAO_0000115> "Confidence statement from weakly conflicting evidence lines of same type, of an overall moderately trusted confidence level.";
  rdfs:comment "Different strategies can be used to define the overall confidence level: for instance, it could be defined based on the confidence level of the most trusted evidence, from the set of evidence lines supporting (not contradicting) the assertion; or, it could be defined based on the number of evidence lines supporting the assertion (e.g., 10 congruent low-confidence evidence lines could allow to have an overall high confidence in an assertion, even if contradicted by one other low-confidence evidence). It is the responsibility of annotation teams to define and communicate the parameters, pertinent to their field, allowing to produce overall confidence levels." .

_:5adf0 a owl:Class;
  owl:intersectionOf _:5ae00 .

_:5ae00 rdf:first <http://purl.obolibrary.org/obo/CIO_0000021>;
  rdf:rest _:5ae20 .

_:5ae20 rdf:first _:5ae10;
  rdf:rest rdf:nil .

_:5ae10 a owl:Restriction;
  owl:onProperty <http://purl.obolibrary.org/obo/has_confidence_level>;
  owl:allValuesFrom <http://purl.obolibrary.org/obo/CIO_0000030> .

_:5ae30 a owl:Restriction;
  owl:onProperty <http://purl.obolibrary.org/obo/has_confidence_level>;
  owl:allValuesFrom <http://purl.obolibrary.org/obo/CIO_0000030> .

_:5ae40 a owl:Axiom;
  <http://www.geneontology.org/formats/oboInOwl#hasDbXref> "Bgee:fbb";
  owl:annotatedTarget "Confidence statement from weakly conflicting evidence lines of same type, of an overall moderately trusted confidence level.";
  owl:annotatedSource <http://purl.obolibrary.org/obo/CIO_0000024>;
  owl:annotatedProperty <http://purl.obolibrary.org/obo/IAO_0000115> .

<http://purl.obolibrary.org/obo/CIO_0000025> a owl:Class;
  rdfs:label "confidence statement from weakly conflicting evidence lines of multiple types, overall confidence high";
  owl:equivalentClass _:5ae50;
  rdfs:subClassOf <http://purl.obolibrary.org/obo/CIO_0000011>, _:5ae90;
  owl:disjointWith <http://purl.obolibrary.org/obo/CIO_0000026>, <http://purl.obolibrary.org/obo/CIO_0000027>;
  <http://www.geneontology.org/formats/oboInOwl#id> "CIO:0000025";
  <http://purl.obolibrary.org/obo/IAO_0000115> "Confidence statement from weakly conflicting evidence lines of multiple types, of an overall high confidence level.";
  rdfs:comment "Different strategies can be used to define the overall confidence level: for instance, it could be defined based on the confidence level of the most trusted evidence, from the set of evidence lines supporting (not contradicting) the assertion; or, it could be defined based on the number of evidence lines supporting the assertion (e.g., 10 congruent low-confidence evidence lines could allow to have an overall high confidence in an assertion, even if contradicted by one other low-confidence evidence). It is the responsibility of annotation teams to define and communicate the parameters, pertinent to their field, allowing to produce overall confidence levels." .

_:5ae50 a owl:Class;
  owl:intersectionOf _:5ae60 .

_:5ae60 rdf:first <http://purl.obolibrary.org/obo/CIO_0000011>;
  rdf:rest _:5ae80 .

_:5ae80 rdf:first _:5ae70;
  rdf:rest rdf:nil .

_:5ae70 a owl:Restriction;
  owl:onProperty <http://purl.obolibrary.org/obo/has_confidence_level>;
  owl:allValuesFrom <http://purl.obolibrary.org/obo/CIO_0000029> .

_:5ae90 a owl:Restriction;
  owl:onProperty <http://purl.obolibrary.org/obo/has_confidence_level>;
  owl:allValuesFrom <http://purl.obolibrary.org/obo/CIO_0000029> .

_:5aea0 a owl:Axiom;
  <http://www.geneontology.org/formats/oboInOwl#hasDbXref> "Bgee:fbb";
  owl:annotatedTarget "Confidence statement from weakly conflicting evidence lines of multiple types, of an overall high confidence level.";
  owl:annotatedSource <http://purl.obolibrary.org/obo/CIO_0000025>;
  owl:annotatedProperty <http://purl.obolibrary.org/obo/IAO_0000115> .

<http://purl.obolibrary.org/obo/CIO_0000026> a owl:Class;
  rdfs:label "confidence statement from weakly conflicting evidence lines of multiple types, overall confidence low";
  owl:equivalentClass _:5aeb0;
  rdfs:subClassOf <http://purl.obolibrary.org/obo/CIO_0000011>, _:5aef0;
  owl:disjointWith <http://purl.obolibrary.org/obo/CIO_0000027>;
  <http://www.geneontology.org/formats/oboInOwl#id> "CIO:0000026";
  <http://purl.obolibrary.org/obo/IAO_0000115> "Confidence statement from weakly conflicting evidence lines of multiple types, of an overall not-trusted confidence level.";
  rdfs:comment "Different strategies can be used to define the overall confidence level: for instance, it could be defined based on the confidence level of the most trusted evidence, from the set of evidence lines supporting (not contradicting) the assertion; or, it could be defined based on the number of evidence lines supporting the assertion (e.g., 10 congruent low-confidence evidence lines could allow to have an overall high confidence in an assertion, even if contradicted by one other low-confidence evidence). It is the responsibility of annotation teams to define and communicate the parameters, pertinent to their field, allowing to produce overall confidence levels.";
  <http://www.geneontology.org/formats/oboInOwl#inSubset> <http://purl.obolibrary.org/obo/cio/#bgee_not_trusted> .

_:5aeb0 a owl:Class;
  owl:intersectionOf _:5aec0 .

_:5aec0 rdf:first <http://purl.obolibrary.org/obo/CIO_0000011>;
  rdf:rest _:5aee0 .

_:5aee0 rdf:first _:5aed0;
  rdf:rest rdf:nil .

_:5aed0 a owl:Restriction;
  owl:onProperty <http://purl.obolibrary.org/obo/has_confidence_level>;
  owl:allValuesFrom <http://purl.obolibrary.org/obo/CIO_0000031> .

_:5aef0 a owl:Restriction;
  owl:onProperty <http://purl.obolibrary.org/obo/has_confidence_level>;
  owl:allValuesFrom <http://purl.obolibrary.org/obo/CIO_0000031> .

_:5af00 a owl:Axiom;
  <http://www.geneontology.org/formats/oboInOwl#hasDbXref> "Bgee:fbb";
  owl:annotatedTarget "Confidence statement from weakly conflicting evidence lines of multiple types, of an overall not-trusted confidence level.";
  owl:annotatedSource <http://purl.obolibrary.org/obo/CIO_0000026>;
  owl:annotatedProperty <http://purl.obolibrary.org/obo/IAO_0000115> .

<http://purl.obolibrary.org/obo/CIO_0000027> a owl:Class;
  rdfs:label "confidence statement from weakly conflicting evidence lines of multiple types, overall confidence medium";
  owl:equivalentClass _:5af10;
  rdfs:subClassOf <http://purl.obolibrary.org/obo/CIO_0000011>, _:5af50;
  <http://www.geneontology.org/formats/oboInOwl#id> "CIO:0000027";
  <http://purl.obolibrary.org/obo/IAO_0000115> "Confidence statement from weakly conflicting evidence lines of multiple types, of an overall moderately trusted confidence level.";
  rdfs:comment "Different strategies can be used to define the overall confidence level: for instance, it could be defined based on the confidence level of the most trusted evidence, from the set of evidence lines supporting (not contradicting) the assertion; or, it could be defined based on the number of evidence lines supporting the assertion (e.g., 10 congruent low-confidence evidence lines could allow to have an overall high confidence in an assertion, even if contradicted by one other low-confidence evidence). It is the responsibility of annotation teams to define and communicate the parameters, pertinent to their field, allowing to produce overall confidence levels." .

_:5af10 a owl:Class;
  owl:intersectionOf _:5af20 .

_:5af20 rdf:first <http://purl.obolibrary.org/obo/CIO_0000011>;
  rdf:rest _:5af40 .

_:5af40 rdf:first _:5af30;
  rdf:rest rdf:nil .

_:5af30 a owl:Restriction;
  owl:onProperty <http://purl.obolibrary.org/obo/has_confidence_level>;
  owl:allValuesFrom <http://purl.obolibrary.org/obo/CIO_0000030> .

_:5af50 a owl:Restriction;
  owl:onProperty <http://purl.obolibrary.org/obo/has_confidence_level>;
  owl:allValuesFrom <http://purl.obolibrary.org/obo/CIO_0000030> .

_:5af60 a owl:Axiom;
  <http://www.geneontology.org/formats/oboInOwl#hasDbXref> "Bgee:fbb";
  owl:annotatedTarget "Confidence statement from weakly conflicting evidence lines of multiple types, of an overall moderately trusted confidence level.";
  owl:annotatedSource <http://purl.obolibrary.org/obo/CIO_0000027>;
  owl:annotatedProperty <http://purl.obolibrary.org/obo/IAO_0000115> .

<http://purl.obolibrary.org/obo/CIO_0000028> a owl:Class;
  rdfs:label "confidence level";
  rdfs:subClassOf <http://purl.obolibrary.org/obo/CIO_0000040>;
  owl:disjointWith <http://purl.obolibrary.org/obo/CIO_0000032>, <http://purl.obolibrary.org/obo/CIO_0000041>;
  <http://purl.obolibrary.org/obo/IAO_0000115> "A confidence information element representing the different levels of confidence, used to compose confidence information statements.";
  <http://www.geneontology.org/formats/oboInOwl#id> "CIO:0000028" .

_:5af70 a owl:Axiom;
  owl:annotatedTarget "A confidence information element representing the different levels of confidence, used to compose confidence information statements.";
  <http://www.geneontology.org/formats/oboInOwl#hasDbXref> "Bgee:fbb";
  owl:annotatedSource <http://purl.obolibrary.org/obo/CIO_0000028>;
  owl:annotatedProperty <http://purl.obolibrary.org/obo/IAO_0000115> .

<http://purl.obolibrary.org/obo/CIO_0000029> a owl:Class;
  rdfs:label "high confidence level";
  rdfs:subClassOf <http://purl.obolibrary.org/obo/CIO_0000028>, _:5af80;
  owl:disjointWith <http://purl.obolibrary.org/obo/CIO_0000030>, <http://purl.obolibrary.org/obo/CIO_0000031>;
  <http://purl.obolibrary.org/obo/IAO_0000115> "A confidence level representing a high trust in an evidence.";
  <http://www.geneontology.org/formats/oboInOwl#id> "CIO:0000029" .

_:5af80 a owl:Restriction;
  owl:onProperty <http://purl.obolibrary.org/obo/provides_greater_confidence_than>;
  owl:someValuesFrom <http://purl.obolibrary.org/obo/CIO_0000030> .

_:5af90 a owl:Axiom;
  owl:annotatedTarget "A confidence level representing a high trust in an evidence.";
  <http://www.geneontology.org/formats/oboInOwl#hasDbXref> "Bgee:fbb";
  owl:annotatedSource <http://purl.obolibrary.org/obo/CIO_0000029>;
  owl:annotatedProperty <http://purl.obolibrary.org/obo/IAO_0000115> .

<http://purl.obolibrary.org/obo/CIO_0000030> a owl:Class;
  rdfs:label "medium confidence level";
  rdfs:subClassOf <http://purl.obolibrary.org/obo/CIO_0000028>, _:5afa0;
  owl:disjointWith <http://purl.obolibrary.org/obo/CIO_0000031>;
  <http://purl.obolibrary.org/obo/IAO_0000115> "A confidence level representing a moderate trust in an evidence.";
  <http://www.geneontology.org/formats/oboInOwl#id> "CIO:0000030" .

_:5afa0 a owl:Restriction;
  owl:onProperty <http://purl.obolibrary.org/obo/provides_greater_confidence_than>;
  owl:someValuesFrom <http://purl.obolibrary.org/obo/CIO_0000031> .

_:5afb0 a owl:Axiom;
  owl:annotatedTarget "A confidence level representing a moderate trust in an evidence.";
  <http://www.geneontology.org/formats/oboInOwl#hasDbXref> "Bgee:fbb";
  owl:annotatedSource <http://purl.obolibrary.org/obo/CIO_0000030>;
  owl:annotatedProperty <http://purl.obolibrary.org/obo/IAO_0000115> .

<http://purl.obolibrary.org/obo/CIO_0000031> a owl:Class;
  rdfs:label "low confidence level";
  rdfs:subClassOf <http://purl.obolibrary.org/obo/CIO_0000028>;
  <http://purl.obolibrary.org/obo/IAO_0000115> "A confidence level representing an absence of trust in an evidence.";
  <http://www.geneontology.org/formats/oboInOwl#id> "CIO:0000031" .

_:5afc0 a owl:Axiom;
  owl:annotatedTarget "A confidence level representing an absence of trust in an evidence.";
  <http://www.geneontology.org/formats/oboInOwl#hasDbXref> "Bgee:fbb";
  owl:annotatedSource <http://purl.obolibrary.org/obo/CIO_0000031>;
  owl:annotatedProperty <http://purl.obolibrary.org/obo/IAO_0000115> .

<http://purl.obolibrary.org/obo/CIO_0000032> a owl:Class;
  rdfs:label "evidence concordance";
  rdfs:subClassOf <http://purl.obolibrary.org/obo/CIO_0000040>;
  owl:disjointWith <http://purl.obolibrary.org/obo/CIO_0000041>;
  <http://purl.obolibrary.org/obo/IAO_0000115> "A confidence information element representing the type of concordance of evidence lines supporting an assertion, used to compose confidence information statements.";
  <http://www.geneontology.org/formats/oboInOwl#id> "CIO:0000032";
  rdfs:comment "Subclasses are used to define whether there is a single evidence, or multiple evidence lines, in support of an assertion, and whether they are congruent or conflicting." .

_:5afd0 a owl:Axiom;
  owl:annotatedTarget "A confidence information element representing the type of concordance of evidence lines supporting an assertion, used to compose confidence information statements.";
  <http://www.geneontology.org/formats/oboInOwl#hasDbXref> "Bgee:fbb";
  owl:annotatedSource <http://purl.obolibrary.org/obo/CIO_0000032>;
  owl:annotatedProperty <http://purl.obolibrary.org/obo/IAO_0000115> .

<http://purl.obolibrary.org/obo/CIO_0000033> a owl:Class;
  rdfs:label "congruent";
  rdfs:subClassOf <http://purl.obolibrary.org/obo/CIO_0000043>;
  owl:disjointWith <http://purl.obolibrary.org/obo/CIO_0000034>;
  <http://purl.obolibrary.org/obo/IAO_0000115> "An evidence concordance of multiple evidence lines that are congruent.";
  <http://www.geneontology.org/formats/oboInOwl#id> "CIO:0000033";
  rdfs:comment "The assumption here is that assertions supported by a single evidence are less trustworthy than assertions supported by multiple evidence lines." .

_:5afe0 a owl:Axiom;
  owl:annotatedTarget "An evidence concordance of multiple evidence lines that are congruent.";
  <http://www.geneontology.org/formats/oboInOwl#hasDbXref> "Bgee:fbb";
  owl:annotatedSource <http://purl.obolibrary.org/obo/CIO_0000033>;
  owl:annotatedProperty <http://purl.obolibrary.org/obo/IAO_0000115> .

<http://purl.obolibrary.org/obo/CIO_0000034> a owl:Class;
  rdfs:label "conflicting";
  rdfs:subClassOf <http://purl.obolibrary.org/obo/CIO_0000043>;
  rdfs:comment "An assertion can have several related evidence lines, some supporting the assertion, and some rejecting the assertion (e.g., using the NOT qualifier in GO annotations).";
  <http://purl.obolibrary.org/obo/IAO_0000115> "An evidence concordance of multiple evidence lines that are conflicting.";
  <http://www.geneontology.org/formats/oboInOwl#id> "CIO:0000034" .

_:5aff0 a owl:Axiom;
  owl:annotatedTarget "An evidence concordance of multiple evidence lines that are conflicting.";
  <http://www.geneontology.org/formats/oboInOwl#hasDbXref> "Bgee:fbb";
  owl:annotatedSource <http://purl.obolibrary.org/obo/CIO_0000034>;
  owl:annotatedProperty <http://purl.obolibrary.org/obo/IAO_0000115> .

<http://purl.obolibrary.org/obo/CIO_0000035> a owl:Class;
  rdfs:label "strongly conflicting";
  rdfs:subClassOf <http://purl.obolibrary.org/obo/CIO_0000034>;
  owl:disjointWith <http://purl.obolibrary.org/obo/CIO_0000036>;
  <http://purl.obolibrary.org/obo/IAO_0000115> "A conflicting concordance for evidence lines that are strongly conflicting.";
  <http://www.geneontology.org/formats/oboInOwl#id> "CIO:0000035";
  rdfs:comment "We distinguish two levels of conflict: weak conflict between evidence lines, e.g., a low confidence evidence negating an assertion, versus several high confidence evidence lines supporting the assertion; and strong conflict between evidence lines, e.g., two high confidence evidence lines contradicting each other. Note that strongly conflicting evidence lines are not used to produce confidence information statements associated to a confidence level (low, medium, high): in that case, the supported assertion is believed to need further validation, as evidence lines yield different conclusions of similar confidence." .

_:5b000 a owl:Axiom;
  owl:annotatedTarget "A conflicting concordance for evidence lines that are strongly conflicting.";
  <http://www.geneontology.org/formats/oboInOwl#hasDbXref> "Bgee:fbb";
  owl:annotatedSource <http://purl.obolibrary.org/obo/CIO_0000035>;
  owl:annotatedProperty <http://purl.obolibrary.org/obo/IAO_0000115> .

<http://purl.obolibrary.org/obo/CIO_0000036> a owl:Class;
  rdfs:label "weakly conflicting";
  rdfs:subClassOf <http://purl.obolibrary.org/obo/CIO_0000034>;
  <http://purl.obolibrary.org/obo/IAO_0000115> "A conflicting concordance for evidence lines that are weakly conflicting.";
  <http://www.geneontology.org/formats/oboInOwl#id> "CIO:0000036";
  rdfs:comment "We distinguish two levels of conflict: weak conflict between evidence lines, e.g., a low confidence evidence negating an assertion, versus several high confidence evidence lines supporting the assertion; and strong conflict between evidence lines, e.g., two high confidence evidence lines contradicting each other." .

_:5b010 a owl:Axiom;
  owl:annotatedTarget "A conflicting concordance for evidence lines that are weakly conflicting.";
  <http://www.geneontology.org/formats/oboInOwl#hasDbXref> "Bgee:fbb";
  owl:annotatedSource <http://purl.obolibrary.org/obo/CIO_0000036>;
  owl:annotatedProperty <http://purl.obolibrary.org/obo/IAO_0000115> .

<http://purl.obolibrary.org/obo/CIO_0000037> a owl:Class;
  rdfs:label "same type";
  rdfs:subClassOf <http://purl.obolibrary.org/obo/CIO_0000041>;
  owl:disjointWith <http://purl.obolibrary.org/obo/CIO_0000038>;
  <http://purl.obolibrary.org/obo/IAO_0000115> "An evidence type concordance for evidence lines that are from a same type.";
  <http://www.geneontology.org/formats/oboInOwl#id> "CIO:0000037" .

_:5b020 a owl:Axiom;
  owl:annotatedTarget "An evidence type concordance for evidence lines that are from a same type.";
  <http://www.geneontology.org/formats/oboInOwl#hasDbXref> "Bgee:fbb";
  owl:annotatedSource <http://purl.obolibrary.org/obo/CIO_0000037>;
  owl:annotatedProperty <http://purl.obolibrary.org/obo/IAO_0000115> .

<http://purl.obolibrary.org/obo/CIO_0000038> a owl:Class;
  rdfs:label "different type";
  rdfs:subClassOf <http://purl.obolibrary.org/obo/CIO_0000041>;
  <http://purl.obolibrary.org/obo/IAO_0000115> "An evidence type concordance for evidence lines that are from different types.";
  <http://www.geneontology.org/formats/oboInOwl#id> "CIO:0000038" .

_:5b030 a owl:Axiom;
  owl:annotatedTarget "An evidence type concordance for evidence lines that are from different types.";
  <http://www.geneontology.org/formats/oboInOwl#hasDbXref> "Bgee:fbb";
  owl:annotatedSource <http://purl.obolibrary.org/obo/CIO_0000038>;
  owl:annotatedProperty <http://purl.obolibrary.org/obo/IAO_0000115> .

<http://purl.obolibrary.org/obo/CIO_0000039> a owl:Class;
  rdfs:label "rejected";
  rdfs:subClassOf <http://purl.obolibrary.org/obo/CIO_0000001>;
  <http://purl.obolibrary.org/obo/IAO_0000115> "A confidence statement from single evidence related to assertions that have been rejected, for instance, following paper retraction, author misinterpretation, or curator misinterpretation.";
  <http://www.geneontology.org/formats/oboInOwl#id> "CIO:0000039";
  rdfs:comment "When results are retracted, associated annotations are often removed. Consequently, end-users might not be aware that the result was annotated. Annotating an assertion with this confidence term allows to keep the information available. Such assertions should not interfer with aggregation of multiple evidence lines to generate a confidence level from the branch CIO:0000002 \"confidence from multiple evidence lines\". This is different from negative annotations, used to negate the interpretation of an annotation. It is also different from conflicting multiple evidence lines, where each single evidence has not been directly invalidated. Rejection is a stronger assertion about an annotation source than conflict, capturing that this evidence should no longer be used." .

_:5b040 a owl:Axiom;
  owl:annotatedTarget "A confidence statement from single evidence related to assertions that have been rejected, for instance, following paper retraction, author misinterpretation, or curator misinterpretation.";
  <http://www.geneontology.org/formats/oboInOwl#hasDbXref> "Bgee:fbb";
  owl:annotatedSource <http://purl.obolibrary.org/obo/CIO_0000039>;
  owl:annotatedProperty <http://purl.obolibrary.org/obo/IAO_0000115> .

<http://purl.obolibrary.org/obo/CIO_0000040> a owl:Class;
  rdfs:label "confidence information element";
  <http://www.geneontology.org/formats/oboInOwl#id> "CIO:0000040";
  <http://purl.obolibrary.org/obo/IAO_0000115> "Confidence information element represent intrinsic properties of confidence information statements, allowing to compose them." .

_:5b050 a owl:Axiom;
  <http://www.geneontology.org/formats/oboInOwl#hasDbXref> "Bgee:fbb";
  owl:annotatedTarget "Confidence information element represent intrinsic properties of confidence information statements, allowing to compose them.";
  owl:annotatedSource <http://purl.obolibrary.org/obo/CIO_0000040>;
  owl:annotatedProperty <http://purl.obolibrary.org/obo/IAO_0000115> .

<http://purl.obolibrary.org/obo/CIO_0000041> a owl:Class;
  rdfs:label "evidence type concordance";
  rdfs:subClassOf <http://purl.obolibrary.org/obo/CIO_0000040>;
  <http://purl.obolibrary.org/obo/IAO_0000115> "A confidence information element representing the concordance of experimental or computational types of evidence lines supporting an assertion, used to compose confidence information statements.";
  <http://www.geneontology.org/formats/oboInOwl#id> "CIO:0000041";
  rdfs:comment "The assumption here is that assertions supported by evidence lines of different experimental or computational types are more trustworthy than assertions supported by evidence lines of a same experimental or computational type." .

_:5b060 a owl:Axiom;
  owl:annotatedTarget "A confidence information element representing the concordance of experimental or computational types of evidence lines supporting an assertion, used to compose confidence information statements.";
  <http://www.geneontology.org/formats/oboInOwl#hasDbXref> "Bgee:fbb";
  owl:annotatedSource <http://purl.obolibrary.org/obo/CIO_0000041>;
  owl:annotatedProperty <http://purl.obolibrary.org/obo/IAO_0000115> .

<http://purl.obolibrary.org/obo/CIO_0000042> a owl:Class;
  rdfs:label "single evidence";
  rdfs:subClassOf <http://purl.obolibrary.org/obo/CIO_0000032>;
  owl:disjointWith <http://purl.obolibrary.org/obo/CIO_0000043>;
  <http://purl.obolibrary.org/obo/IAO_0000115> "An evidence concordance for confidence information about an assertion produced from a single evidence.";
  <http://www.geneontology.org/formats/oboInOwl#id> "CIO:0000042";
  rdfs:comment "The assumption here is that assertions supported by a single evidence are less trustworthy than assertions supported by multiple evidence lines." .

_:5b070 a owl:Axiom;
  owl:annotatedTarget "An evidence concordance for confidence information about an assertion produced from a single evidence.";
  <http://www.geneontology.org/formats/oboInOwl#hasDbXref> "Bgee:fbb";
  owl:annotatedSource <http://purl.obolibrary.org/obo/CIO_0000042>;
  owl:annotatedProperty <http://purl.obolibrary.org/obo/IAO_0000115> .

<http://purl.obolibrary.org/obo/CIO_0000043> a owl:Class;
  rdfs:label "concordance of multiple evidence lines";
  rdfs:subClassOf <http://purl.obolibrary.org/obo/CIO_0000032>;
  <http://purl.obolibrary.org/obo/IAO_0000115> "An evidence concordance for confidence information about an assertion produced from multiple evidence lines.";
  <http://www.geneontology.org/formats/oboInOwl#id> "CIO:0000043";
  rdfs:comment "The assumption here is that assertions supported by a single evidence are less trustworthy than assertions supported by multiple evidence lines." .

_:5b080 a owl:Axiom;
  owl:annotatedTarget "An evidence concordance for confidence information about an assertion produced from multiple evidence lines.";
  <http://www.geneontology.org/formats/oboInOwl#hasDbXref> "Bgee:fbb";
  owl:annotatedSource <http://purl.obolibrary.org/obo/CIO_0000043>;
  owl:annotatedProperty <http://purl.obolibrary.org/obo/IAO_0000115> .
