PREFIX obo: PREFIX rdf: PREFIX rdfs: PREFIX xsd: obo:HP_0040197 a rdfs:Class ; rdfs:label "Encephalomalacia" ; rdfs:comment "Encephalomalacia is the softening or loss of brain tissue after cerebral infarction, cerebral ischemia, infection, craniocerebral trauma, or other injury." ; rdfs:subClassOf obo:HP_0012443 . obo:RO_0000059 a rdf:Property ; rdfs:label "concretizes"@en ; rdfs:comment "A relationship between a specifically dependent continuant and a generically dependent continuant, in which the generically dependent continuant depends on some independent continuant in virtue of the fact that the specifically dependent continuant also depends on that same independent continuant. Multiple specifically dependent continuants can concretize the same generically dependent continuant."@en ; rdfs:domain obo:BFO_0000020 ; rdfs:range obo:BFO_0000031 . obo:BFO_0000059 a rdf:Property ; rdfs:label "concretizes at some time"@en ; rdfs:domain obo:BFO_0000020 ; rdfs:range obo:BFO_0000031 . obo:BFO_0000108 a rdf:Property ; rdfs:label "exists at"@en ; rdfs:domain obo:BFO_0000001 ; rdfs:range obo:BFO_0000008 . obo:BFO_0000169 a rdf:Property ; rdfs:label "specifically depends on at some time"@en ; rdfs:range . obo:BFO_0000176 a rdf:Property ; rdfs:label "part of continuant at some time"@en ; rdfs:comment "[copied from inverse property 'has continuant part at some time'] b has_continuant_part c at t = Def. c continuant_part_of b at t. (axiom label in BFO2 Reference: [006-001])" ; rdfs:domain obo:BFO_0000002 ; rdfs:range obo:BFO_0000002 . obo:BFO_0000187 a rdf:Property ; rdfs:label "has continuant part at all times that part exists"@en ; rdfs:comment "forall(t) exists_at(y,t) -> exists_at(x,t) and 'has continuant part'(x,y,t)" ; rdfs:domain obo:BFO_0000002 ; rdfs:range obo:BFO_0000002 ; rdfs:subPropertyOf obo:BFO_0000178 . obo:BFO_0000052 a rdf:Property ; rdfs:label "inheres in at all times"@en ; rdfs:comment "b inheres_in c at t =Def. b is a dependent continuant & c is an independent continuant that is not a spatial region & b s-depends_on c at t. (axiom label in BFO2 Reference: [051-002])"@en ; rdfs:domain obo:BFO_0000020 ; rdfs:range ; rdfs:subPropertyOf obo:BFO_0000070 . obo:BFO_0000050 a rdf:Property ; rdfs:label "part of" ; rdfs:comment "a core relation that holds between a part and its whole"@en ; rdfs:seeAlso , , ; rdfs:domain obo:BFO_0000001 ; rdfs:range obo:BFO_0000001 ; rdfs:subPropertyOf obo:RO_0002131 . obo:BFO_0000178 a rdf:Property ; rdfs:label "has continuant part at some time"@en ; rdfs:comment "b has_continuant_part c at t = Def. c continuant_part_of b at t. (axiom label in BFO2 Reference: [006-001])"@en ; rdfs:domain obo:BFO_0000002 ; rdfs:range obo:BFO_0000002 . obo:RO_0000056 a rdf:Property ; rdfs:label "participates in"@en ; rdfs:comment "a relation between a continuant and a process, in which the continuant is somehow involved in the process"@en ; rdfs:domain obo:BFO_0000002 ; rdfs:range obo:BFO_0000003 . obo:CHEBI_33673 a rdfs:Class ; rdfs:label "zinc group molecular entity" ; rdfs:subClassOf obo:CHEBI_33676 . obo:BFO_0000083 a rdf:Property ; rdfs:label "occupies spatial region at some time"@en ; rdfs:domain obo:BFO_0000004 ; rdfs:range obo:BFO_0000006 . obo:BFO_0000073 a rdf:Property ; rdfs:label "is granular part of"@en ; rdfs:domain obo:BFO_0000040 ; rdfs:range obo:BFO_0000040 ; rdfs:subPropertyOf obo:BFO_0000050 . obo:OBI_1110119 a rdf:Property ; rdfs:label "bound_to" ; rdfs:comment "A relationship between two material entities that form a complex based on a selective, non-covalent interaction." ; rdfs:domain obo:BFO_0000040 ; rdfs:range obo:BFO_0000040 . obo:CIDO_0000119 a rdf:Property ; rdfs:label "chemical inhibits protein"@en ; rdfs:comment "An object property that represents a relation between a chemical entity and a protein where the chemical entity can target the protein as an enzyme inhibitor. Note that the chemical entity is usually an active compound of a corresponding drug." ; rdfs:domain obo:CHEBI_24431 ; rdfs:range obo:PR_000000001 ; rdfs:subPropertyOf obo:CIDO_0000118 . obo:RO_0001025 a rdf:Property ; rdfs:label "located in"@en ; rdfs:comment "a relation between two independent continuants, the target and the location, in which the target is entirely within the location"@en ; rdfs:domain obo:BFO_0000004 ; rdfs:range . obo:VO_0005242 a rdf:Property ; rdfs:label "up-expressed as immune signature of"@en ; rdfs:comment "An object property that represents a relation between a material entity and biological process" ; rdfs:domain obo:BFO_0000040 ; rdfs:range obo:BFO_0000015 . obo:CIDO_0000417 a rdf:Property ; rdfs:label "secreted from"@en ; rdfs:comment "An object property that represents a relation between a material entity (e.g., gene or protein) that is secreted from another material entity (e.g., cell)." ; rdfs:domain obo:BFO_0000040 ; rdfs:range obo:BFO_0000040 . obo:CIDO_0000184 a rdf:Property ; rdfs:label "capable of inhibiting activity of"@en ; rdfs:comment "An object property between material entity a and b where a is capable of inhibiting the activity of b." ; rdfs:domain obo:BFO_0000040 ; rdfs:range obo:BFO_0000040 ; rdfs:subPropertyOf obo:RO_0002410 . obo:RO_0000087 a rdf:Property ; rdfs:label "has role" ; rdfs:comment "a relation between an independent continuant (the bearer) and a role, in which the role specifically depends on the bearer for its existence"@en ; rdfs:domain obo:BFO_0000004 ; rdfs:range obo:BFO_0000023 ; rdfs:subPropertyOf obo:RO_0000053 . obo:RO_0000085 a rdf:Property ; rdfs:label "has function"@en ; rdfs:comment "a relation between an independent continuant (the bearer) and a function, in which the function specifically depends on the bearer for its existence"@en ; rdfs:domain obo:BFO_0000004 ; rdfs:range obo:BFO_0000034 ; rdfs:subPropertyOf obo:RO_0000053 . obo:CIDO_0000249 a rdf:Property ; rdfs:label "agent capable of inducing phenotype"@en ; rdfs:comment "a causal relation between a material entity and a phenotype where the material agent is capable of inducing the phenotype." ; rdfs:domain obo:BFO_0000040 ; rdfs:range ; rdfs:subPropertyOf obo:CIDO_0000220 . obo:RO_0001000 a rdf:Property ; rdfs:label "derives from"@en ; rdfs:comment "a relation between two distinct material entities, the new entity and the old entity, in which the new entity begins to exist when the old entity ceases to exist, and the new entity inherits the significant portion of the matter of the old entity"@en ; rdfs:domain obo:BFO_0000004 ; rdfs:range obo:BFO_0000004 . obo:OBI_0000304 a rdf:Property ; rdfs:label "is_manufactured_by"@en ; rdfs:comment "c is_manufactured_by o means that there was a process p in which c was built in which a person, or set of people or machines did the work(bore the \"Manufacturer Role\", and those people/and or machines were members or of directed by the organization to do this."@en ; rdfs:domain obo:BFO_0000040 ; rdfs:range xsd:string . obo:CIDO_0000030 a rdf:Property ; rdfs:label "susceptible to adverse event"@en ; rdfs:comment "An object property that represents a relation between a material entity (such as a drug or chemical or vaccine) and an adverse event (AE) where the administration of the material entity is susceptible to the presence of the adverse event." ; rdfs:domain obo:BFO_0000040 ; rdfs:range obo:OAE_0000001 . obo:NCBITaxon_574549 a rdfs:Class ; rdfs:label "Bulbul coronavirus HKU11" ; rdfs:subClassOf obo:NCBITaxon_2509474 . obo:BFO_0000051 a rdf:Property ; rdfs:label "has part" ; rdfs:comment "a core relation that holds between a whole and its part"@en ; rdfs:range ; rdfs:subPropertyOf obo:RO_0002131 . obo:CIDO_0000433 a rdf:Property ; rdfs:label "has motivation"@en ; rdfs:range obo:CIDO_0000434 . obo:CIDO_0000298 a rdf:Property ; rdfs:label "organism susceptibly has up-regulated gene"@en ; rdfs:comment "An object property that represents a relation between an organism and a gene where the organism is susceptible to have an up-regulation of the expression of the gene." ; rdfs:domain obo:OBI_0100026 ; rdfs:range obo:OGG_0000000002 . obo:HP_0001928 a rdfs:Class ; rdfs:label "Abnormality of coagulation" ; rdfs:comment "An abnormality of the process of blood coagulation. That is, altered ability or inability of the blood to clot." ; rdfs:subClassOf obo:HP_0001871 . obo:PR_000010137 a rdfs:Class ; rdfs:label "mitogen-activated protein kinase kinase kinase 4" ; rdfs:comment "A protein that is a translation product of the human MAP3K4 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . a rdf:Property ; rdfs:label "is tautomer of" ; rdfs:range . a rdf:Property ; rdfs:label "has parent hydride" ; rdfs:range . obo:VO_0005079 a rdfs:Class ; rdfs:label "AV-COVID-19"@en ; rdfs:comment "A SARS-CoV-2 vaccine consisting of autologous dendritic cells previously loaded ex vivo with spike protein." ; rdfs:subClassOf obo:VO_0005199 . obo:VO_0004909 a rdf:Property ; rdfs:label "immunizes against disease process"@en ; rdfs:comment "A shortcut object property that represents a relation between a vaccine and a disease process where the vaccine immunizes a host against a disease process." ; rdfs:range . obo:OBI_0000312 a rdf:Property ; rdfs:label "is_specified_output_of" ; rdfs:comment "A relation between a planned process and a continuant participating in that process. The presence of the continuant at the end of the process is explicitly specified in the objective specification which the process realizes the concretization of."@en ; rdfs:domain obo:BFO_0000002 ; rdfs:range obo:OBI_0000011 , obo:OBI_0600044 ; rdfs:subPropertyOf obo:RO_0000056 . obo:VO_0000520 a rdf:Property ; rdfs:label "has vaccine component" ; rdfs:comment "an object property that defines a relation between a vaccine and its component" ; rdfs:domain obo:VO_0000001 ; rdfs:range . obo:VO_0003355 a rdf:Property ; rdfs:label "immunizes against microbe" ; rdfs:comment """a shortcut relation that equals to: processed material and (is_specified_output_of some vaccine preparation) and (has function some (vaccine function and (is realized by only (vaccine immunization and (realizes some ('immunization target role' and (role_of some 'MICROBE')))))))) The domain of this relation is a vaccine. The range of this relation is a microbe (a bacterium, a virus, a fungus, and a parasite)""" ; rdfs:range . obo:VO_0000547 a rdf:Property ; rdfs:label "vaccinated in route" ; rdfs:comment "an object property that specifies a relation between a vaccine and a vaccinate route" ; rdfs:domain obo:VO_0000001 ; rdfs:range obo:VO_0000574 . obo:VO_0001243 a rdf:Property ; rdfs:label "immunizes host" ; rdfs:comment """a shortcut relation that equals to: 'processed material' and (is_specified_output_of some 'vaccine preparation') and ('has function' some ('vaccine function' and ('is realized by' only ('vaccine immunization' and (realizes some ('vaccine host role' and (role_of some 'organism')))))))). The domain of this relation is a vaccine. The range of this relation is a organism."""@en ; rdfs:domain obo:VO_0000001 ; rdfs:range obo:OBI_0100026 . obo:VO_0000524 a rdf:Property ; rdfs:label "has vaccine antigen" ; rdfs:comment "an object property that specifies a vaccine antigen" ; rdfs:domain obo:VO_0000001 ; rdfs:range ; rdfs:subPropertyOf obo:VO_0000520 . obo:NCBITaxon_249088 a rdfs:Class ; rdfs:label "SARS coronavirus ZS-C" ; rdfs:subClassOf obo:NCBITaxon_694009 . obo:CIDO_0000593 a rdfs:Class ; rdfs:label "AA variant in SARS-CoV-2 S protein S1 RBD region"@en ; rdfs:comment "An AA variant that is located in the RBD of SARS-CoV-2 S protein. In the original Wuhan strain, this contains amino acids from position 306-527." ; rdfs:subClassOf obo:CIDO_0000592 . obo:CIDO_0000244 a rdf:Property ; rdfs:label "variant of"@en ; rdfs:comment "An object property that represents a relation between a molecular variant and a gene or protein where the variant derives from the gene or protein" ; rdfs:domain obo:BFO_0000001 ; rdfs:range obo:BFO_0000001 ; rdfs:subPropertyOf obo:BFO_0000050 . obo:PR_000001488 a rdfs:Class ; rdfs:label "muscarinic acetylcholine receptor" ; rdfs:comment "A rhodopsin-like G-protein coupled receptor that is a translation product of the human CHRM1 to CHRM5 genes, 1:1 orthologs thereof, or a semi-ortholog thereof." ; rdfs:subClassOf obo:PR_000001094 . obo:CHEBI_134158 a rdfs:Class ; rdfs:label "N-acylethanolamine 18:1" ; rdfs:comment "An N-acylethanolamine in which the acyl group contains 18 carbons and 1 double bond." ; rdfs:subClassOf obo:CHEBI_85282 . a rdf:Property ; rdfs:label "has functional parent" ; rdfs:range . obo:CHEBI_137114 a rdfs:Class ; rdfs:label "bromodomain-containing protein 4 inhibitor" ; rdfs:comment "Any inhibitor of bromodomain-containing protein 4 (BRD4)." ; rdfs:subClassOf obo:CHEBI_35222 , obo:CHEBI_52206 . obo:BFO_0000054 a rdf:Property ; rdfs:label "realized in"@en ; rdfs:comment "Paraphrase of elucidation: a relation between a realizable entity and a process, where there is some material entity that is bearer of the realizable entity and participates in the process, and the realizable entity comes to be realized in the course of the process" ; rdfs:domain obo:BFO_0000017 ; rdfs:range obo:BFO_0000015 , obo:GO_0006955 , obo:OBI_0000415 , obo:OBI_0000274 , obo:OBI_0000070 , obo:OBI_1110014 . obo:CHEBI_83982 a rdfs:Class ; rdfs:label "L-glutamic acid derivative" ; rdfs:comment "A proteinogenic amino acid derivative resulting from reaction of L-glutamic acid at the amino group or either of the carboxy groups, or from the replacement of any hydrogen of L-glutamic acid by a heteroatom." ; rdfs:subClassOf obo:CHEBI_24315 , obo:CHEBI_83811 . obo:CHEBI_28044 a rdfs:Class ; rdfs:label "phenylalanine" ; rdfs:comment "An aromatic amino acid that is alanine in which one of the methyl hydrogens is substituted by a phenyl group." ; rdfs:subClassOf obo:CHEBI_33704 , obo:CHEBI_33856 . a rdf:Property ; rdfs:label "is conjugate acid of" ; rdfs:range . a rdf:Property ; rdfs:label "is conjugate base of" ; rdfs:range . obo:OBI_0600044 a rdfs:Class ; rdfs:label "lavage"@en ; rdfs:comment "A protocol application to separate cells and/or cellular secretions from an anatomical space by the introduction and removal of fluid"@en ; rdfs:subClassOf obo:OBI_0600005 , obo:OBI_0600014 . obo:BFO_0000062 a rdf:Property ; rdfs:label "preceded by"@en ; rdfs:comment "x is preceded by y if and only if the time point at which y ends is before or equivalent to the time point at which x starts. Formally: x preceded by y iff ω(y) <= α(x), where α is a function that maps a process to a start point, and ω is a function that maps a process to an end point."@en ; rdfs:domain obo:BFO_0000003 ; rdfs:range obo:BFO_0000003 ; rdfs:subPropertyOf obo:RO_0002086 . obo:CIDO_0000208 a rdf:Property ; rdfs:label "catalyzed by"@en ; rdfs:comment "a subproperty of 'enabled by' that represents a relation between a process and an enzyme where a protein is catalyzed by the enzyme in a catalytic reaction" ; rdfs:domain obo:BFO_0000015 ; rdfs:range obo:PR_000000001 ; rdfs:subPropertyOf obo:RO_0002233 . obo:BFO_0000132 a rdf:Property ; rdfs:label "part of occurrent"@en ; rdfs:comment "[copied from inverse property 'has occurrent part'] b has_occurrent_part c = Def. c occurrent_part_of b. (axiom label in BFO2 Reference: [007-001])" ; rdfs:domain obo:BFO_0000003 ; rdfs:range obo:BFO_0000003 . obo:BFO_0000063 a rdf:Property ; rdfs:label "precedes"@en ; rdfs:comment "x precedes y if and only if the time point at which x ends is before or equivalent to the time point at which y starts. Formally: x precedes y iff ω(x) <= α(y), where α is a function that maps a process to a start point, and ω is a function that maps a process to an end point."@en ; rdfs:domain obo:BFO_0000003 ; rdfs:range obo:BFO_0000003 ; rdfs:subPropertyOf obo:RO_0002222 . obo:BFO_0000155 a rdf:Property ; rdfs:label "occupies temporal region"@en ; rdfs:domain obo:BFO_0000003 ; rdfs:range obo:BFO_0000008 ; rdfs:subPropertyOf obo:BFO_0000108 . obo:BFO_0000117 a rdf:Property ; rdfs:label "has occurrent part"@en ; rdfs:comment "b has_occurrent_part c = Def. c occurrent_part_of b. (axiom label in BFO2 Reference: [007-001])"@en ; rdfs:domain obo:BFO_0000003 ; rdfs:range obo:BFO_0000003 . obo:BFO_0000139 a rdf:Property ; rdfs:label "temporal part of"@en ; rdfs:comment "b proper_temporal_part_of c =Def. b temporal_part_of c & not (b = c). (axiom label in BFO2 Reference: [116-001])"@en ; rdfs:domain obo:BFO_0000003 ; rdfs:range obo:BFO_0000003 ; rdfs:subPropertyOf obo:BFO_0000132 . obo:CIDO_0000176 a rdf:Property ; rdfs:label "susceptibly occurs in"@en ; rdfs:comment "An object property that represents a relation between a process and a material entity (particularly an organism, anatomical entity, or cell) in which the process has a susceptible disposition to occur." ; rdfs:domain obo:BFO_0000015 ; rdfs:range obo:BFO_0000040 . obo:OBI_0000417 a rdf:Property ; rdfs:label "achieves_planned_objective" ; rdfs:comment "This relation obtains between a planned process and a objective specification when the criteria specified in the objective specification are met at the end of the planned process." ; rdfs:domain obo:OBI_0000011 ; rdfs:range obo:IAO_0000005 . obo:OBI_0000293 a rdf:Property ; rdfs:label "has_specified_input"@en ; rdfs:comment "A relation between a planned process and a continuant participating in that process that is not created during the process. The presence of the continuant during the process is explicitly specified in the plan specification which the process realizes the concretization of."@en ; rdfs:domain obo:OBI_0000011 ; rdfs:range obo:BFO_0000040 , obo:BFO_0000002 , obo:IAO_0000027 ; rdfs:subPropertyOf obo:RO_0000057 . obo:OBI_0000299 a rdf:Property ; rdfs:label "has_specified_output"@en ; rdfs:comment "A relation between a planned process and a continuant participating in that process. The presence of the continuant at the end of the process is explicitly specified in the objective specification which the process realizes the concretization of."@en ; rdfs:domain obo:OBI_0000011 ; rdfs:range obo:BFO_0000002 , obo:IAO_0000027 ; rdfs:subPropertyOf obo:RO_0000057 . obo:BFO_0000055 a rdf:Property ; rdfs:label "realizes"@en ; rdfs:comment "Paraphrase of elucidation: a relation between a process and a realizable entity, where there is some material entity that is bearer of the realizable entity and participates in the process, and the realizable entity comes to be realized in the course of the process" ; rdfs:domain obo:BFO_0000015 ; rdfs:range obo:BFO_0000017 . obo:RO_0000057 a rdf:Property ; rdfs:label "has_participant" ; rdfs:comment "a relation between a process and a continuant, in which the continuant is somehow involved in the process"@en ; rdfs:domain obo:BFO_0000003 ; rdfs:range obo:BFO_0000002 . obo:BFO_0000130 a rdf:Property ; rdfs:label "occupies spatiotemporal region"@en ; rdfs:domain obo:BFO_0000003 ; rdfs:range obo:BFO_0000011 . obo:BFO_0000138 a rdf:Property ; rdfs:label "proper part of occurrent"@en ; rdfs:comment "[copied from inverse property 'has proper occurrent part'] b has_proper_occurrent_part c = Def. c proper_occurrent_part_of b. [XXX-001" ; rdfs:domain obo:BFO_0000003 ; rdfs:range obo:BFO_0000003 ; rdfs:subPropertyOf obo:BFO_0000132 . obo:BFO_0000118 a rdf:Property ; rdfs:label "has proper occurrent part"@en ; rdfs:comment "[copied from inverse property 'proper part of occurrent'] b proper_occurrent_part_of c =Def. b occurrent_part_of c & b and c are not identical. (axiom label in BFO2 Reference: [005-001])" ; rdfs:domain obo:BFO_0000003 ; rdfs:range obo:BFO_0000003 ; rdfs:subPropertyOf obo:BFO_0000117 . obo:CIDO_0000248 a rdf:Property ; rdfs:label "process capable of inducing phenotype"@en ; rdfs:comment "a causal relation between a process and a phenotype where the process is capable of inducing the phenotype." ; rdfs:domain obo:BFO_0000015 ; rdfs:range ; rdfs:subPropertyOf obo:CIDO_0000220 . obo:NCBITaxon_384338 a rdfs:Class ; rdfs:label "Human coronavirus NO/0749/04" ; rdfs:subClassOf obo:NCBITaxon_384335 . obo:GO_0060627 a rdfs:Class ; rdfs:label "regulation of vesicle-mediated transport" ; rdfs:comment "Any process that modulates the rate, frequency, or extent of vesicle-mediated transport, the directed movement of substances, either within a vesicle or in the vesicle membrane, into, out of or within a cell." ; rdfs:subClassOf obo:GO_0050794 , obo:GO_0051049 . obo:NCBITaxon_376913 a rdfs:Class ; rdfs:label "Haplorrhini" ; rdfs:subClassOf obo:NCBITaxon_9443 . obo:PR_000002067 a rdfs:Class ; rdfs:label "poliovirus receptor" ; rdfs:comment "A poliovirus receptor-related protein that is a translation product of the human PVR gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000001911 . obo:CIDO_0000153 a rdfs:Class ; rdfs:label "coronaviral disease epidemic"@en ; rdfs:subClassOf obo:IDO_0000502 . obo:NCBITaxon_864603 a rdfs:Class ; rdfs:label "Bat coronavirus BM98-05/BGR/2008" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:HP_0025143 a rdfs:Class ; rdfs:label "Chills"@en ; rdfs:comment "A sudden sensation of feeling cold." ; rdfs:subClassOf obo:HP_0025142 . obo:CHEBI_37070 a rdfs:Class ; rdfs:label "2-methylbutyric acid" ; rdfs:comment "A methylbutyric acid comprising a butyric acid core carrying a 2-methyl substituent. Produced from amino acid leucine during nutrient starvation in bacteria." ; rdfs:subClassOf obo:CHEBI_38653 . obo:OGG_3043740577 a rdfs:Class ; rdfs:label "ORF8 of severe acute respiratory syndrome coronavirus 2" ; rdfs:subClassOf obo:OGG_2002697049 . obo:OGG_0000000029 a rdf:Property ; rdfs:label "has GO association"@en ; rdfs:comment "an annotation property that shows the GO information associated with a specific gene. " ; rdfs:domain obo:OGG_0000000002 ; rdfs:range xsd:string . obo:OGG_0000000016 a rdf:Property ; rdfs:label "is gene of organism"@en ; rdfs:comment "a relation between a gene and the organism where this gene belongs to the organism in nature. It does not include a foreign gene that is transferred to an organism by a genetic engineering method. " ; rdfs:domain obo:OGG_0000000002 ; rdfs:range obo:OBI_0100026 ; rdfs:subPropertyOf obo:BFO_0000050 . obo:PR_Q12770 a rdfs:Class ; rdfs:label "sterol regulatory element-binding protein cleavage-activating protein (human)" ; rdfs:comment "A sterol regulatory element-binding protein cleavage-activating protein that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000014489 , obo:PR_000029067 . obo:RO_0002160 a rdf:Property ; rdfs:label "only in taxon" ; rdfs:comment "x only in taxon y if and only if x is in taxon y, and there is no other organism z such that y!=z a and x is in taxon z." ; rdfs:seeAlso ; rdfs:range . obo:CIDO_0020117 a rdfs:Class ; rdfs:label "Dimension EXL SARS‑CoV‑2 IgG (CV2G)" ; rdfs:seeAlso ; rdfs:subClassOf obo:CIDO_0000454 . obo:CIDO_0000024 a rdf:Property ; rdfs:label "EUA-authorized use at"@en ; rdfs:domain obo:CIDO_0000454 ; rdfs:range obo:OBI_0000245 , obo:CIDO_0000458 . obo:RO_0002215 a rdf:Property ; rdfs:label "capable of"@en ; rdfs:comment "A relation between a material entity (such as a cell) and a process, in which the material entity has the ability to carry out the process. " ; rdfs:range ; rdfs:subPropertyOf obo:RO_0002216 . obo:DOID_13027 a rdfs:Class ; rdfs:label "transient global amnesia" ; rdfs:comment "An amnestic disorder that is characterized by temporary but almost total disruption of short-term memory with a range of problems accessing older memories." ; rdfs:subClassOf obo:DOID_10914 . obo:CIDO_0000219 a rdf:Property ; rdfs:label "disease induced by phenotype"@en ; rdfs:comment "A causal relationship with disease as subject that shows that the realization of the disease is caused by a phenotype." ; rdfs:domain obo:OGMS_0000031 ; rdfs:range ; rdfs:subPropertyOf obo:RO_0004023 . obo:PR_000001167 a rdfs:Class ; rdfs:label "5-hydroxytryptamine receptor 2B" ; rdfs:comment "A 5-hydroxytryptamine receptor 2 that is a translation product of the human HTR2B gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000001099 . obo:NCBITaxon_1643330 a rdfs:Class ; rdfs:label "Suncus coronavirus" ; rdfs:subClassOf obo:NCBITaxon_2664420 . a rdfs:Class ; rdfs:label "Pimozide [Chemical/Ingredient]" ; rdfs:subClassOf . obo:NCBITaxon_461308 a rdfs:Class ; rdfs:label "Rocky Mountain Bat Coronavirus 6" ; rdfs:subClassOf obo:NCBITaxon_366617 . obo:CHEBI_140325 a rdfs:Class ; rdfs:label "secondary carboxamide" ; rdfs:comment "A carboxamide resulting from the formal condensation of a carboxylic acid with a primary amine; formula RC(=O)NHR(1)." ; rdfs:subClassOf obo:CHEBI_37622 . obo:CIDO_0000558 a rdfs:Class ; rdfs:label "TLFKFLLLLYAIYAL" ; rdfs:comment "A coronavirus epitope that is part of some S protein from HCoV NL63 composed of the following amino acids TLFKFLLLLYAIYAL" ; rdfs:subClassOf obo:CIDO_0000449 . obo:CIDO_0000312 a rdf:Property ; rdfs:label "homologous epitope of"@en ; rdfs:comment "An object property that represents a relation between two epitopes X and Y where X is an homologous epitope of Y." ; rdfs:range . obo:CHEBI_5123 a rdfs:Class ; rdfs:label "fluphenazine" ; rdfs:comment "A phenothiazine derivative having a trifluoromethyl subsitituent at the 2-position and a 3-[4-(2-hydroxyethyl)piperazin-1-yl]propyl group at the N-10 position." ; rdfs:subClassOf obo:CHEBI_37143 , obo:CHEBI_38093 , obo:CHEBI_46845 . obo:CIDO_0000118 a rdf:Property ; rdfs:label "chemical has protein target"@en ; rdfs:comment "An object property that represents a relation between a chemical entity and a protein where the chemical entity can target the protein. Note that the chemical entity is usually an active compound of a corresponding drug." ; rdfs:range . obo:CIDO_0000120 a rdf:Property ; rdfs:label "chemical has protein target as antagonist"@en ; rdfs:comment "An object property that represents a relation between a chemical entity and a protein where the chemical entity can target the protein as an receptor antagonist. Note that the chemical entity is usually an active compound of a corresponding drug." ; rdfs:range ; rdfs:subPropertyOf obo:CIDO_0000118 . obo:HP_0012723 a rdfs:Class ; rdfs:label "Sinoatrial block" ; rdfs:comment "Disturbance in the atrial activation that is caused by transient failure of impulse conduction from the sinoatrial node to the cardiac atria." ; rdfs:subClassOf obo:HP_0011702 , obo:HP_0012722 . a rdfs:Class ; rdfs:label "Heterocyclic Compounds [Chemical/Ingredient]" ; rdfs:subClassOf . obo:CHEBI_29360 a rdfs:Class ; rdfs:label "methanediide" ; rdfs:subClassOf obo:CHEBI_38222 . obo:HP_0001939 a rdfs:Class ; rdfs:label "Abnormality of metabolism/homeostasis" ; rdfs:subClassOf obo:HP_0000118 . obo:NCBITaxon_2691591 a rdfs:Class ; rdfs:label "unclassified Pedacovirus" ; rdfs:subClassOf obo:NCBITaxon_2509505 . obo:GO_0022890 a rdfs:Class ; rdfs:label "inorganic cation transmembrane transporter activity" ; rdfs:comment "Enables the transfer of inorganic cations from one side of a membrane to the other. Inorganic cations are atoms or small molecules with a positive charge that do not contain carbon in covalent linkage." ; rdfs:subClassOf obo:GO_0015075 , obo:GO_0015318 . obo:PR_000001938 a rdfs:Class ; rdfs:label "thrombomodulin-like receptor" ; rdfs:comment "A protein with core architecture consisting of a signal sequence, a Lectin C-type domain (Pfam:PF00059), 5 or 6 EGF-like domains (Pfam:PF00008, Pfam:PF09064, or Pfam:PF07645), a transmembrane region, and a small cytoplasmic region (36-51 amino acids)." ; rdfs:subClassOf obo:PR_000000001 . obo:PR_Q96D53 a rdfs:Class ; rdfs:label "atypical kinase COQ8B, mitochondrial (human)" ; rdfs:comment "An atypical kinase COQ8B, mitochondrial that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000029067 , obo:PR_000029090 . obo:VO_0005106 a rdfs:Class ; rdfs:label "SARS tPA-S DNA vaccine" ; rdfs:comment "A SARS DNA vaccine that is made from tpa-optimize800 DNA with SARS-CoV S protein" ; rdfs:subClassOf obo:VO_0012183 . obo:CHEBI_145932 a rdfs:Class ; rdfs:label "(S)-2-methylbutanoate" ; rdfs:comment "A branched-chain saturated fatty acid anion resulting from the deprotonation of the carboxy group of (S)-2-methylbutanoic acid. The major species at pH 7.3." ; rdfs:subClassOf obo:CHEBI_58951 , obo:CHEBI_58956 , obo:CHEBI_83976 . obo:PR_P50406 a rdfs:Class ; rdfs:label "5-hydroxytryptamine receptor 6 (human)" ; rdfs:comment "A 5-hydroxytryptamine receptor 6 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000001102 , obo:PR_000029067 . obo:NCBITaxon_1679898 a rdfs:Class ; rdfs:label "Coronavirus RCoV/D_RMU10_2070/Myo_gla/GER/2010" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:APOLLO_SV_00000230 a rdfs:Class ; rdfs:label "case isolation control strategy"@en ; rdfs:comment "an infectious disease control strategy that has an action specification that is realized in isolating organsims who are infectious."@en ; rdfs:subClassOf obo:APOLLO_SV_00000086 . obo:OBI_0001938 a rdf:Property ; rdfs:label "has value specification" ; rdfs:comment "A relation between an information content entity and a value specification that specifies its value." ; rdfs:domain obo:IAO_0000030 ; rdfs:range obo:OBI_0001933 ; rdfs:subPropertyOf obo:BFO_0000051 . obo:BFO_0000058 a rdf:Property ; rdfs:label "concretized by at some time"@en ; rdfs:domain obo:BFO_0000031 ; rdfs:range obo:BFO_0000020 . obo:IAO_0000136 a rdf:Property ; rdfs:label "is about" ; rdfs:comment "is_about is a (currently) primitive relation that relates an information artifact to an entity."@en ; rdfs:domain obo:IAO_0000030 ; rdfs:range . obo:GO_0048678 a rdfs:Class ; rdfs:label "response to axon injury" ; rdfs:comment "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an axon injury stimulus." ; rdfs:subClassOf obo:GO_0009611 . obo:CHEBI_63452 a rdfs:Class ; rdfs:label "midostaurin" ; rdfs:comment "An organic heterooctacyclic compound that is the N-benzoyl derivative of staurosporine." ; rdfs:subClassOf obo:CHEBI_22702 , obo:CHEBI_38165 , obo:CHEBI_51915 , obo:CHEBI_74222 . obo:has_role a rdf:Property ; rdfs:range . obo:DOID_934 a rdfs:Class ; rdfs:label "viral infectious disease" ; rdfs:comment "A disease by infectious agent that results in infection, has_material_basis_in Viruses." ; rdfs:subClassOf obo:IDO_0000436 . obo:VO_0000147 a rdfs:Class ; rdfs:label "vaccine adjuvant role" ; rdfs:comment "an adjuvant role that inheres in a vaccine component which is added as part of a vaccine and induces enhanced adaptive immune response to the vaccine antigen. " ; rdfs:subClassOf obo:VO_0000415 . obo:NCBITaxon_117571 a rdfs:Class ; rdfs:label "Euteleostomi" ; rdfs:subClassOf obo:NCBITaxon_117570 , obo:NCBITaxon_7742 . obo:CIDO_0000113 a rdfs:Class ; rdfs:label "modulation of host response to SARS-CoV infection"@en ; rdfs:comment "A process that modulates host response to SARS-CoV viral infection" ; rdfs:subClassOf obo:CIDO_0000111 . obo:CHEBI_27477 a rdfs:Class ; rdfs:label "D-valine" ; rdfs:comment "The D-enantiomer of valine." ; rdfs:subClassOf obo:CHEBI_16733 , obo:CHEBI_27266 . a rdf:Property ; rdfs:label "is enantiomer of" ; rdfs:range . obo:OAE_0002807 a rdfs:Class ; rdfs:label "medical procedure"@en ; rdfs:comment "a medical intervention that refers to any series of pre-defined steps that should be followed to achieve a desired result." ; rdfs:subClassOf obo:OBI_0000011 . obo:PR_000001784 a rdfs:Class ; rdfs:label "interleukin-1 receptor-associated kinase 3" ; rdfs:comment "An interleukin-1 receptor-associated kinase IRAK1/3 that is a translation product of the human IRAK3 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000001781 . obo:GO_0018108 a rdfs:Class ; rdfs:label "peptidyl-tyrosine phosphorylation" ; rdfs:comment "The phosphorylation of peptidyl-tyrosine to form peptidyl-O4'-phospho-L-tyrosine." ; rdfs:subClassOf obo:GO_0006464 , obo:GO_0006468 . a rdfs:Class ; rdfs:label "Amebiasis [Disease/Finding]" ; rdfs:subClassOf . obo:PR_Q9ULT8 a rdfs:Class ; rdfs:label "E3 ubiquitin-protein ligase HECTD1 (human)" ; rdfs:comment "An E3 ubiquitin-protein ligase HECTD1 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000008502 , obo:PR_000029067 . obo:PR_O95747 a rdfs:Class ; rdfs:label "serine/threonine-protein kinase OSR1 (human)" ; rdfs:comment "A serine/threonine-protein kinase OSR1 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000012099 , obo:PR_000029067 . obo:CIDO_0020272 a rdfs:Class ; rdfs:label "SARS-CoV-2 IgG assay" ; rdfs:seeAlso ; rdfs:subClassOf obo:CIDO_0000454 . obo:DOID_11162 a rdfs:Class ; rdfs:label "respiratory failure" ; rdfs:comment "A lung disease characterized by inadequate gas exchange by the respiratory system." ; rdfs:subClassOf obo:DOID_850 . obo:CIDO_0000569 a rdfs:Class ; rdfs:label "VQIDRLINGRLTALN" ; rdfs:comment "A coronavirus epitope that is part of some S protein from HCoV HKU1 composed of the following amino acids VQIDRLINGRLTALN" ; rdfs:subClassOf obo:CIDO_0000450 . obo:CHEBI_8764 a rdfs:Class ; rdfs:label "mycophenolate mofetil" ; rdfs:comment "A carboxylic ester resulting from the formal condensation between the carboxylic acid group of mycophenolic acid and the hydroxy group of 2-(morpholin-4-yl)ethanol. In the liver, it is metabolised to mycophenolic acid, an immunosuppressant for which it is a prodrug. It is widely used to prevent tissue rejection following organ transplants as well as for the treatment of certain autoimmune diseases." ; rdfs:subClassOf obo:CHEBI_25698 , obo:CHEBI_33308 , obo:CHEBI_33853 , obo:CHEBI_37581 , obo:CHEBI_50996 . obo:CIDO_0000123 a rdf:Property ; rdfs:label "chemical induces protein"@en ; rdfs:comment "An object property that represents a relation between a chemical entity and a protein where the chemical entity can target the protein as an enzyme inducer. Note that the chemical entity is usually an active compound of a corresponding drug. An enzyme inducer is a type of chemical that increases the metabolic activity of an enzyme either by binding to the enzyme and activating it, or by increasing the expression of the gene coding for the enzyme." ; rdfs:range ; rdfs:subPropertyOf obo:CIDO_0000118 . obo:CIDO_0000144 a rdf:Property ; rdfs:label "chemical inhibits in vitro replication of virus"@en ; rdfs:comment "An object property that represents a relation between a chemical entity and a virus where the chemical has an effective role against viral replication in vitro" ; rdfs:range ; rdfs:subPropertyOf obo:CIDO_0000150 , obo:CIDO_0000141 . obo:CHEBI_51689 a rdfs:Class ; rdfs:label "enone" ; rdfs:comment "An alpha,beta-unsaturated ketone of general formula R(1)R(2)C=CR(3)-C(=O)R(4) (R(4) =/= H) in which the C=O function is conjugated to a C=C double bond at the alpha,beta position." ; rdfs:subClassOf obo:CHEBI_51721 , obo:CHEBI_78840 . obo:PR_P31645 a rdfs:Class ; rdfs:label "sodium-dependent serotonin transporter (human)" ; rdfs:comment "A sodium-dependent serotonin transporter that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000015189 , obo:PR_000029067 . obo:PR_Q9UKE5 a rdfs:Class ; rdfs:label "TRAF2 and NCK-interacting protein kinase (human)" ; rdfs:comment "A TRAF2 and NCK-interacting protein kinase that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000016491 , obo:PR_000029067 . obo:CHEBI_46851 a rdfs:Class ; rdfs:label "N-(2-hydroxyethyl)piperazine" ; rdfs:subClassOf obo:CHEBI_23981 , obo:CHEBI_46845 . obo:VO_0005164 a rdfs:Class ; rdfs:label "ARCT-021" ; rdfs:comment "A SARS-CoV-2 investigational vaccine comprising a self-replicating (replicon) mRNA that encodes for the prefusion spike protein of 2019-nCoV formulated in a lipid nanoparticle" ; rdfs:subClassOf obo:VO_0005198 . obo:VO_0000530 a rdf:Property ; rdfs:label "has vaccine vector" ; rdfs:comment "a type of 'has vaccine component' relation that is specifically for vaccine vector component" ; rdfs:domain obo:VO_0000001 ; rdfs:range obo:VO_0000599 ; rdfs:subPropertyOf obo:VO_0000520 . obo:PR_000006359 a rdfs:Class ; rdfs:label "nucleolar RNA helicase 2" ; rdfs:comment "A protein that is a translation product of the human DDX21 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:OBI_0000094 a rdfs:Class ; rdfs:label "material processing"@en ; rdfs:comment "A planned process which results in physical changes in a specified input material"@en ; rdfs:subClassOf obo:OBI_0000011 . a rdfs:Class ; rdfs:label "Colonic Diseases, Functional [Disease/Finding]" ; rdfs:subClassOf . obo:PR_A2QLK4 a rdfs:Class ; rdfs:subClassOf obo:PR_000000001 . obo:NCBITaxon_9845 a rdfs:Class ; rdfs:label "Ruminantia" ; rdfs:subClassOf obo:NCBITaxon_91561 . obo:NCBITaxon_550971 a rdfs:Class ; rdfs:label "Bat coronavirus R.aur/Australia/CoV000/2006" ; rdfs:subClassOf obo:NCBITaxon_696098 . obo:CIDO_0000276 a rdfs:Class ; rdfs:label "Y144- in SARS-CoV-2 S protein" ; rdfs:comment "Y144del in SARS-CoV-2 S protein" ; rdfs:subClassOf obo:CIDO_0001144 . obo:CIDO_0000706 a rdf:Property ; rdfs:label "is characteristic AA mutation of"@en ; rdfs:comment "An object property that defines a relation between a microbe variant and an AA mutation where the microbe (like SARS_CoV-2) variant has the AA mutation such that the microbe variant has an AA change that is used to identify a microbe variant. This is used over AA variant for deletions or nonsense mutations." ; rdfs:range ; rdfs:subPropertyOf obo:CIDO_0000609 . obo:DOID_0050177 a rdfs:Class ; rdfs:label "monogenic disease" ; rdfs:comment "A genetic disease that is the result of one or more abnormal alleles and may be dominant, semi-dominant, or recessive." ; rdfs:subClassOf obo:DOID_630 . obo:NCBITaxon_9838 a rdfs:Class ; rdfs:label "Camelus dromedarius" ; rdfs:subClassOf obo:NCBITaxon_9836 . obo:CIDO_0000948 a rdfs:Class ; rdfs:label "SARS-CoV2 nsp9 protein binding to human EIF4H" ; rdfs:comment "SARS-CoV2 nsp9 protein binding to human EIF4H, as evidented by an affinity-purification mass spectrometry experiment" ; rdfs:subClassOf obo:CIDO_0000583 . obo:CIDO_0000273 a rdfs:Class ; rdfs:label "SARS-CoV-2 clade GV"@en ; rdfs:subClassOf obo:CIDO_0000232 . obo:CIDO_0000281 a rdf:Property ; rdfs:label "has characteristic AA variant"@en ; rdfs:comment "An object property that defines a relation between a microbe variant and an AA variant where the microbe (like SARS_CoV-2) variant has the AA variant such that the microbe variant changes its AA from a previous one to a new one." ; rdfs:range ; rdfs:subPropertyOf obo:CIDO_0000603 . obo:NCBITaxon_249077 a rdfs:Class ; rdfs:label "SARS coronavirus HZS2-C" ; rdfs:subClassOf obo:NCBITaxon_694009 . obo:NCBITaxon_681862 a rdfs:Class ; rdfs:label "Kenya bat coronavirus BtKY15" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:PR_O75534 a rdfs:Class ; rdfs:label "cold shock domain-containing protein E1 (human)" ; rdfs:comment "A cold shock domain-containing protein E1 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000005928 , obo:PR_000029067 . obo:CHEBI_33554 a rdfs:Class ; rdfs:label "organosulfonate oxoanion" ; rdfs:comment "An organic anion obtained by deprotonation of the sufonate group(s) of any organosulfonic acid." ; rdfs:subClassOf obo:CHEBI_25696 . obo:PR_000014493 a rdfs:Class ; rdfs:label "scavenger receptor class B member 1" ; rdfs:comment "A protein that is a translation product of the human SCARB1 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:VO_0005243 a rdfs:Class ; rdfs:label "CoviVac"@en ; rdfs:comment "A SARS-CoV-2 inactivated whole virus vaccine developed by the Chumakov Centre at the Russian Academy of Sciences" ; rdfs:subClassOf obo:VO_0005266 . obo:PR_000002344 a rdfs:Class ; rdfs:label "protein kinase C theta type" ; rdfs:comment "A protein kinase C, delta-like that is a translation product of the human PRKCQ gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000002210 . obo:PR_Q9H8W4 a rdfs:Class ; rdfs:label "pleckstrin homology domain-containing family F member 2 (human)" ; rdfs:comment "A pleckstrin homology domain-containing family F member 2 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000029067 , obo:PR_000029676 . obo:PR_000004950 a rdfs:Class ; rdfs:label "voltage-dependent calcium channel gamma-1 subunit" ; rdfs:comment "A protein that is a translation product of the human CACNG1 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:OAE_0000392 a rdfs:Class ; rdfs:label "paresthesia AE" ; rdfs:comment "a sensory neuropathy AE that shows a sensation of tingling, pricking, or numbness of a person's skin with no apparent long-term physical effect." ; rdfs:subClassOf obo:OAE_0000162 . obo:PR_Q2M389 a rdfs:Class ; rdfs:label "WASH complex subunit 4 (human)" ; rdfs:comment "A WASH complex subunit 4 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000029067 , obo:PR_000060149 . obo:HP_0011842 a rdfs:Class ; rdfs:label "Abnormality of skeletal morphology" ; rdfs:comment "An abnormality of the form, structure, or size of the skeletal system." ; rdfs:subClassOf obo:HP_0000924 . obo:PR_000010187 a rdfs:Class ; rdfs:label "serine/threonine-protein kinase MARK2" ; rdfs:comment "A protein that is a translation product of the human MARK2 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:CIDO_0000856 a rdfs:Class ; rdfs:label "SARS-CoV2 nsp13 protein binding to human RDX" ; rdfs:comment "SARS-CoV2 nsp13 protein binding to human RDX, as evidented by an affinity-purification mass spectrometry experiment" ; rdfs:subClassOf obo:CIDO_0000058 . obo:NCBITaxon_337687 a rdfs:Class ; rdfs:label "Muroidea" ; rdfs:subClassOf obo:NCBITaxon_1963758 . obo:VO_0005124 a rdfs:Class ; rdfs:label "MERS rNTD vaccine" ; rdfs:comment "A MERS subunit vaccine made of a neutralizing monoclonal antibodiesagainst MERS-CoV which bind to the N-terminal domain (NTD) of the MERS-CoV S1 subunit that was expressed by baculovirus-insect cell sf9-derived recombinant MERS-CoV." ; rdfs:subClassOf obo:VO_0004900 . obo:VO_0005137 a rdfs:Class ; rdfs:label "MVA-MERS vaccine" ; rdfs:comment "A MERS VLP vaccine made from a recombinant baculovirus co-expresssing the spike S, envelope (E), and membrane (M) proteins of MERS." ; rdfs:subClassOf obo:VO_0004900 . obo:GO_0051174 a rdfs:Class ; rdfs:label "regulation of phosphorus metabolic process" ; rdfs:comment "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving phosphorus or compounds containing phosphorus." ; rdfs:subClassOf obo:GO_0031323 . obo:NCBITaxon_745724 a rdfs:Class ; rdfs:label "Coronavirus N.noc/VM182/2007/NLD" ; rdfs:subClassOf obo:NCBITaxon_696098 . obo:CIDO_0000975 a rdfs:Class ; rdfs:label "SARS-CoV2 orf3a protein binding to human HMOX1" ; rdfs:comment "SARS-CoV2 orf3a protein binding to human HMOX1, as evidented by an affinity-purification mass spectrometry experiment" ; rdfs:subClassOf obo:CIDO_0000584 . obo:OBI_0000655 a rdfs:Class ; rdfs:label "blood specimen" ; rdfs:comment "a material entity derived from a portion of blood collected from an organism" ; rdfs:subClassOf obo:OBI_2000009 . obo:HP_0002597 a rdfs:Class ; rdfs:label "Abnormality of the vasculature" ; rdfs:comment "An abnormality of the vasculature." ; rdfs:subClassOf obo:HP_0001626 . obo:NCBITaxon_2042701 a rdfs:Class ; rdfs:label "Vespertilionid betacoronavirus" ; rdfs:subClassOf obo:NCBITaxon_696098 . obo:OGG_0000000002 a rdfs:Class ; rdfs:label "gene"@en ; rdfs:comment "A gene is a material entity that represents the entire DNA sequence required for synthesis of a functional protein or RNA molecule. " ; rdfs:subClassOf obo:BFO_0000040 . obo:NCBITaxon_903620 a rdfs:Class ; rdfs:label "Kenya bat coronavirus BtKY82" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:GO_0019220 a rdfs:Class ; rdfs:label "regulation of phosphate metabolic process" ; rdfs:comment "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving phosphates." ; rdfs:subClassOf obo:GO_0051174 . obo:PR_Q9P2K8 a rdfs:Class ; rdfs:label "eIF-2-alpha kinase GCN2 (human)" ; rdfs:comment "An eIF-2-alpha kinase GCN2 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000006961 , obo:PR_000029067 . obo:PR_P23219 a rdfs:Class ; rdfs:label "prostaglandin G/H synthase 1 (human)" ; rdfs:comment "A prostaglandin G/H synthase 1 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000013427 , obo:PR_000029067 . obo:CHEBI_63046 a rdfs:Class ; rdfs:label "emulsifier" ; rdfs:comment "The chemical role played by a substance that stabilizes an emulsion by increasing its kinetic stability." ; rdfs:subClassOf obo:CHEBI_51086 . obo:PR_000016496 a rdfs:Class ; rdfs:label "activated CDC42 kinase 1" ; rdfs:comment "A protein that is a translation product of the human TNK2 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:VO_0005203 a rdfs:Class ; rdfs:label "COVID-19 DNA vaccine"@en ; rdfs:subClassOf obo:VO_0004908 . obo:CIDO_0001048 a rdfs:Class ; rdfs:label "SARS-CoV2 orf9c protein binding to human DPY19L1" ; rdfs:comment "SARS-CoV2 orf9c protein binding to human DPY19L1, as evidented by an affinity-purification mass spectrometry experiment" ; rdfs:subClassOf obo:CIDO_0000054 . obo:CIDO_0000750 a rdfs:Class ; rdfs:label "SARS-CoV2 M protein binding to human ANO6" ; rdfs:comment "SARS-CoV2 M protein binding to human ANO6, as evidented by an affinity-purification mass spectrometry experiment" ; rdfs:subClassOf obo:CIDO_0000055 . obo:CIDO_0000467 a rdfs:Class ; rdfs:label "AEALNNLLQQLSNRF" ; rdfs:comment "A coronavirus epitope that is part of some S protein from HCoV OC43 composed of the following amino acids AEALNNLLQQLSNRF" ; rdfs:subClassOf obo:CIDO_0000452 . obo:NCBITaxon_1289555 a rdfs:Class ; rdfs:label "Coronavirus Mex_CoV-9" ; rdfs:subClassOf obo:NCBITaxon_696098 . obo:BFO_0000034 a rdfs:Class ; rdfs:label "function"@en ; rdfs:subClassOf obo:BFO_0000016 , obo:BFO_0000017 . obo:RO_0000079 a rdf:Property ; rdfs:label "function of"@en ; rdfs:comment "a relation between a function and an independent continuant (the bearer), in which the function specifically depends on the bearer for its existence"@en ; rdfs:domain obo:BFO_0000034 ; rdfs:range ; rdfs:subPropertyOf obo:RO_0000052 . a rdfs:Class ; rdfs:label "Otitis Media [Disease/Finding]" ; rdfs:subClassOf . obo:CHEBI_33318 a rdfs:Class ; rdfs:label "main group element atom" ; rdfs:comment "An atom belonging to one of the main groups (found in the s- and p- blocks) of the periodic table." ; rdfs:subClassOf obo:CHEBI_33250 . obo:CIDO_0000052 a rdfs:Class ; rdfs:label "SARS-CoV-2 Orf9b protein interaction with host protein"@en ; rdfs:comment "A molecular interaction that has participant of the SARS-CoV-2 Orf9b protein and a host protein" ; rdfs:subClassOf obo:CIDO_0000348 . obo:OAE_0000300 a rdfs:Class ; rdfs:label "anxiety AE" ; rdfs:comment "a psychiatric disorder AE that has an outcome of a psychological and physiological state characterized by cognitive, somatic, emotional, and behavioral components. These components combine to create an unpleasant feeling that is typically associated with uneasiness, fear, or worry." ; rdfs:subClassOf obo:OAE_0001797 . obo:CIDO_0020130 a rdfs:Class ; rdfs:label "ePlex Respiratory Pathogen Panel 2" ; rdfs:seeAlso ; rdfs:subClassOf obo:CIDO_0000454 . obo:PR_000015753 a rdfs:Class ; rdfs:label "serine/threonine-protein kinase 36" ; rdfs:comment "A protein that is a translation product of the human STK36 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:NCBITaxon_277944 a rdfs:Class ; rdfs:label "Human coronavirus NL63" ; rdfs:subClassOf obo:NCBITaxon_2509512 . obo:CHEBI_7640 a rdfs:Class ; rdfs:label "nortriptyline" ; rdfs:comment "A tricyclic antidepressant that has formula C19H21N." ; rdfs:subClassOf obo:CHEBI_36809 . obo:BFO_0000053 a rdf:Property ; rdfs:label "is_bearer_of" ; rdfs:range . obo:CHEBI_88227 a rdfs:Class ; rdfs:label "potassium ionophore" ; rdfs:comment "Any ionophore capable of transportation of potassium ions across membranes." ; rdfs:subClassOf obo:CHEBI_24869 . obo:GO_0060158 a rdfs:Class ; rdfs:label "phospholipase C-activating dopamine receptor signaling pathway" ; rdfs:comment "A phospholipase C-activating receptor G protein-coupled receptor signaling pathway initiated by dopamine binding to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription." ; rdfs:subClassOf obo:GO_0007200 , obo:GO_0007212 . obo:NCBITaxon_1788490 a rdfs:Class ; rdfs:label "Rhinolophus bat coronavirus BtCoV/4017-1" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:NCBITaxon_227984 a rdfs:Class ; rdfs:label "SARS coronavirus Tor2" ; rdfs:subClassOf obo:NCBITaxon_694009 . obo:PR_000003197 a rdfs:Class ; rdfs:label "calcium/calmodulin-dependent protein kinase type II chain" ; rdfs:comment "A protein with a core domain architecture consisting of a Protein kinase domain (Pfam:PF00069) and a C-terminal Calcium/calmodulin dependent protein kinase II Association (Pfam:PF08332) domain." ; rdfs:subClassOf obo:PR_000000001 . obo:NCBITaxon_1525854 a rdfs:Class ; rdfs:label "Swine deltacoronavirus OhioCVM1/2014" ; rdfs:subClassOf obo:NCBITaxon_1159905 . obo:CHEBI_38263 a rdfs:Class ; rdfs:label "2-amino-3-hydroxybutanoic acid" ; rdfs:comment "An alpha-amino acid that is butanoic acid substituted by an amino group at position 2 and a hydroxy group at position 3." ; rdfs:subClassOf obo:CHEBI_33704 . obo:CHEBI_50905 a rdfs:Class ; rdfs:label "teratogenic agent" ; rdfs:comment "A role played by a chemical compound in biological systems with adverse consequences in embryo developments, leading to birth defects, embryo death or altered development, growth retardation and functional defect." ; rdfs:subClassOf obo:CHEBI_52209 . obo:VariO_0012 a rdfs:Class ; rdfs:label "protein variation type" ; rdfs:comment "Type of protein variation. Describes origin and classification of a variant." ; rdfs:subClassOf obo:VariO_0002 . obo:BFO_0000017 a rdfs:Class ; rdfs:label "realizable entity"@en ; rdfs:comment "A specifically dependent continuant that inheres in continuant entities and are not exhibited in full at every time in which it inheres in an entity or group of entities. The exhibition or actualization of a realizable entity is a particular manifestation, functioning or process that occurs under certain circumstances."@en ; rdfs:subClassOf obo:BFO_0000020 . obo:PR_000029489 a rdfs:Class ; rdfs:label "protein FAM8A1" ; rdfs:comment "A protein that is a translation product of the human FAM8A1 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:NCBITaxon_1381359 a rdfs:Class ; rdfs:label "Bat Coronavirus Taper/CII_KSA_287/Bisha/Saudi Arabia/2012" ; rdfs:subClassOf obo:NCBITaxon_696098 . obo:UBERON_0001988 a rdfs:Class ; rdfs:label "feces" ; rdfs:comment "Portion of semisolid bodily waste discharged through the anus[MW,modified]" ; rdfs:subClassOf obo:UBERON_0000463 , obo:UBERON_0000465 . obo:CIDO_0000056 a rdfs:Class ; rdfs:label "SARS-CoV-2 N protein interaction with host protein"@en ; rdfs:comment "A molecular interaction that has participant of the SARS-CoV-2 N protein and a host protein" ; rdfs:subClassOf obo:CIDO_0000348 . obo:PR_Q15759 a rdfs:Class ; rdfs:label "mitogen-activated protein kinase 11 (human)" ; rdfs:comment "A mitogen-activated protein kinase 11 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000010152 , obo:PR_000029067 . obo:NCBITaxon_1261615 a rdfs:Class ; rdfs:label "Rhinolophus bat coronavirus/Rwanda/445/2008" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:CHEBI_64571 a rdfs:Class ; rdfs:label "NMDA receptor agonist" ; rdfs:comment "An excitatory amino acid agonist which binds to NMDA receptors and triggers a response." ; rdfs:subClassOf obo:CHEBI_50103 . obo:PR_000013575 a rdfs:Class ; rdfs:label "sulfhydryl oxidase 2" ; rdfs:comment "A protein that is a translation product of the human QSOX2 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:PR_P21964 a rdfs:Class ; rdfs:label "catechol O-methyltransferase (human)" ; rdfs:comment "A catechol O-methyltransferase that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000005731 , obo:PR_000029067 . obo:CIDO_0020167 a rdfs:Class ; rdfs:label "Helix COVID-19 Test" ; rdfs:seeAlso ; rdfs:subClassOf obo:CIDO_0000454 . obo:CIDO_0000029 a rdf:Property ; rdfs:label "PCR kit detects gene"@en ; rdfs:comment "A short-cut relation that represents a direct relationship between a PCR test kit and the target gene (or gene region) that the test kit is designed to run a PCR assay for amplifying and detecting the targeted gene or gene region." ; rdfs:range . obo:CIDO_0000138 a rdfs:Class ; rdfs:label "SARS-CoV-2 binding to human cell"@en ; rdfs:comment "A host-coronovirus interaction that involves in the SARS-CoV-2 virus binding to a host cell" ; rdfs:subClassOf obo:CIDO_0000135 . obo:CIDO_0000270 a rdf:Property ; rdfs:label "has receptor"@en ; rdfs:comment "A subproperty of 'has participant' that represents a relation between a process and a participant where the participant has the receptor role." ; rdfs:domain obo:BFO_0000003 ; rdfs:range obo:BFO_0000002 ; rdfs:subPropertyOf obo:RO_0000057 . obo:CIDO_0000269 a rdf:Property ; rdfs:label "has ligand"@en ; rdfs:comment "A subproperty of 'has participant' that represents a relation between a process and a participant where the participant has the ligand role." ; rdfs:domain obo:BFO_0000003 ; rdfs:range obo:BFO_0000002 ; rdfs:subPropertyOf obo:RO_0000057 . obo:NCBITaxon_572289 a rdfs:Class ; rdfs:label "Munia coronavirus HKU13-3514" ; rdfs:subClassOf obo:NCBITaxon_1297661 . obo:NCBITaxon_1433215 a rdfs:Class ; rdfs:label "Bottlenose dolphin coronavirus HKU22" ; rdfs:subClassOf obo:NCBITaxon_694015 . obo:CHEBI_16235 a rdfs:Class ; rdfs:label "guanine" ; rdfs:comment "A 2-aminopurine carrying a 6-oxo substituent." ; rdfs:subClassOf obo:CHEBI_20702 , obo:CHEBI_25810 , obo:CHEBI_26386 . obo:NCBITaxon_231430 a rdfs:Class ; rdfs:label "Turkey coronavirus (strain Minnesota)" ; rdfs:subClassOf obo:NCBITaxon_11152 . obo:OBI_0002126 a rdfs:Class ; rdfs:label "IHC-stained fixed tissue slide specimen"@en ; rdfs:comment "A fixed tissue slide specimen that is the output of immunohistochemistry slide staining."@en ; rdfs:subClassOf obo:OMIABIS_0000052 . obo:PR_Q13724 a rdfs:Class ; rdfs:label "mannosyl-oligosaccharide glucosidase (human)" ; rdfs:comment "A mannosyl-oligosaccharide glucosidase that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000010518 , obo:PR_000029067 . obo:NCBITaxon_1288693 a rdfs:Class ; rdfs:label "Bat coronavirus POA/2012/94" ; rdfs:subClassOf obo:NCBITaxon_366617 . obo:OBI_0000869 a rdfs:Class ; rdfs:label "polyA RNA extract" ; rdfs:comment "A RNA extract that is the output of an extraction process in which RNA molecules with poly A tail at its 3' end are purified." ; rdfs:subClassOf obo:OBI_0000880 . obo:OBI_0000643 a rdf:Property ; rdfs:label "has grain" ; rdfs:comment "the relation of the cells in the finger of the skin to the finger, in which an indeterminate number of grains are parts of the whole by virtue of being grains in a collective that is part of the whole, and in which removing one granular part does not nec- essarily damage or diminish the whole. Ontological Whether there is a fixed, or nearly fixed number of parts - e.g. fingers of the hand, chambers of the heart, or wheels of a car - such that there can be a notion of a single one being missing, or whether, by contrast, the number of parts is indeterminate - e.g., cells in the skin of the hand, red cells in blood, or rubber molecules in the tread of the tire of the wheel of the car." ; rdfs:range , obo:CHEBI_23367 , obo:CL_0000010 ; rdfs:subPropertyOf obo:BFO_0000051 . obo:CIDO_0000867 a rdfs:Class ; rdfs:label "SARS-CoV2 nsp15 protein binding to human NUTF2" ; rdfs:comment "SARS-CoV2 nsp15 protein binding to human NUTF2, as evidented by an affinity-purification mass spectrometry experiment" ; rdfs:subClassOf obo:CIDO_0000347 . a rdfs:Class ; rdfs:label "Aminoquinolines [Chemical/Ingredient]" ; rdfs:subClassOf . a rdfs:Class ; rdfs:label "Amides [Chemical/Ingredient]" ; rdfs:subClassOf . obo:CIDO_0000344 a rdfs:Class ; rdfs:label "YEQYIKWPWYIWLGF"@en ; rdfs:subClassOf obo:CIDO_0000314 . obo:HP_0001962 a rdfs:Class ; rdfs:label "Palpitations" ; rdfs:comment "A sensation that the heart is pounding or racing, which is a non-specific sign but may be a manifestation of arrhythmia." ; rdfs:subClassOf obo:HP_0011675 . obo:CIDO_0020000 a rdfs:Class ; rdfs:label "1copy COVID-19 qPCR Multi Kit" ; rdfs:seeAlso ; rdfs:subClassOf obo:CIDO_0000454 . obo:CIDO_0000625 a rdfs:Class ; rdfs:label "Q19E in SARS-CoV-2 M protein" ; rdfs:comment "An AA mutation or AA variant that has mutated an amino acid at position 19 into a glutamine in M protein." ; rdfs:subClassOf obo:CIDO_0000619 . obo:CIDO_0000707 a rdf:Property ; rdfs:label "has mutated from"@en ; rdfs:range . obo:CIDO_0000613 a rdf:Property ; rdfs:label "has amino acid position"@en ; rdfs:range . obo:CIDO_0000705 a rdf:Property ; rdfs:label "is characteristic AA variant of"@en ; rdfs:comment "An object property that defines a relation between an AA variant and a microbe variant where the microbe (like SARS_CoV-2) variant has the AA variant such that the microbe variant changes its AA from a previous one to a new one and that such a variant is used to identify a microbe variant.." ; rdfs:range ; rdfs:subPropertyOf obo:CIDO_0000600 . obo:CHEBI_3540 a rdfs:Class ; rdfs:label "cephalotaxine" ; rdfs:comment "A benzazepine alkaloid isolated from Cephalotaxus harringtonia." ; rdfs:subClassOf obo:CHEBI_35681 , obo:CHEBI_38164 , obo:CHEBI_38523 , obo:CHEBI_38527 , obo:CHEBI_47985 , obo:CHEBI_50996 , obo:CHEBI_59770 . obo:OBI_0002544 a rdfs:Class ; rdfs:label "esophagogastric junction specimen" ; rdfs:comment "A specimen that is derived from the esophagogastric junction." ; rdfs:subClassOf obo:OBI_0001479 . obo:NCBITaxon_2801853 a rdfs:Class ; rdfs:label "Bat coronavirus RacCS253" ; rdfs:subClassOf obo:NCBITaxon_1986197 . obo:CIDO_0000960 a rdfs:Class ; rdfs:label "SARS-CoV2 nsp9 protein binding to human NUP88" ; rdfs:comment "SARS-CoV2 nsp9 protein binding to human NUP88, as evidented by an affinity-purification mass spectrometry experiment" ; rdfs:subClassOf obo:CIDO_0000583 . obo:UBERON_0000465 a rdfs:Class ; rdfs:label "material anatomical entity" ; rdfs:comment "Anatomical entity that has mass." ; rdfs:subClassOf obo:BFO_0000040 , obo:UBERON_0001062 . a rdfs:Class ; rdfs:label "Peptic Ulcer [Disease/Finding]" ; rdfs:subClassOf , . obo:PR_000010396 a rdfs:Class ; rdfs:label "E3 ubiquitin-protein ligase MIB1" ; rdfs:comment "A protein that is a translation product of the human MIB1 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:PR_O00469 a rdfs:Class ; rdfs:label "procollagen-lysine,2-oxoglutarate 5-dioxygenase 2 (human)" ; rdfs:comment "A procollagen-lysine,2-oxoglutarate 5-dioxygenase 2 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000012877 , obo:PR_000029067 . obo:NCBITaxon_2042543 a rdfs:Class ; rdfs:label "Coronavirus PREDICT CoV-17" ; rdfs:subClassOf obo:NCBITaxon_696098 . obo:OPMI_0000552 a rdfs:Class ; rdfs:label "contributory cause of death status"@en ; rdfs:comment "A contributory cause of death is a significant condition that unfavourably influences the course of the morbid process and thus contributes to the fatal outcome, but which is not related to the disease or condition directly causing death." ; rdfs:subClassOf obo:OPMI_0000533 . obo:CHEBI_5623 a rdfs:Class ; rdfs:label "harman" ; rdfs:comment "An indole alkaloid fundamental parent with a structure of 9H-beta-carboline carrying a methyl substituent at C-1. It has been isolated from the bark of Sickingia rubra, Symplocus racemosa, Passiflora incarnata, Peganum harmala, Banisteriopsis caapi and Tribulus terrestris, as well as from tobacco smoke. It is a specific, reversible inhibitor of monoamine oxidase A." ; rdfs:subClassOf obo:CHEBI_38482 , obo:CHEBI_38958 , obo:CHEBI_61379 . obo:PR_Q70EL1 a rdfs:Class ; rdfs:label "inactive ubiquitin carboxyl-terminal hydrolase 54 (human)" ; rdfs:comment "An inactive ubiquitin carboxyl-terminal hydrolase 54 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000017193 , obo:PR_000029067 . obo:CHEBI_48633 a rdfs:Class ; rdfs:label "piperidinium ion" ; rdfs:subClassOf obo:CHEBI_25697 , obo:CHEBI_35274 . a rdfs:Class ; rdfs:label "Rhinitis, Allergic, Perennial [Disease/Finding]" ; rdfs:subClassOf , . obo:CHEBI_45525 a rdfs:Class ; rdfs:label "(R)-2-methylbutyric acid" ; rdfs:comment "The (R)-enantiomer of 2-methylbutanoic acid." ; rdfs:subClassOf obo:CHEBI_37070 . obo:CIDO_0001080 a rdfs:Class ; rdfs:label "AA variant in SARS-CoV-2 nsp9 protein"@en ; rdfs:comment "An AA variant in SARS-CoV-2 nsp9 protein. Equivalent to an AA variant in SARS-CoV-2 rep 1ab with an AA position of 4118 - 4230." ; rdfs:subClassOf obo:CIDO_0000714 . obo:HP_0004754 a rdfs:Class ; rdfs:label "Permanent atrial fibrillation" ; rdfs:comment "AF that cannot be successfully terminated by cardioversion, and longstanding (more than 1 year) AF, where cardioversion is not indicated or has not been attempted, is termed permanent." ; rdfs:subClassOf obo:HP_0005110 . obo:PR_000011307 a rdfs:Class ; rdfs:label "nucleolar protein 10" ; rdfs:comment "A protein that is a translation product of the human NOL10 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:PR_000009065 a rdfs:Class ; rdfs:label "insulin receptor-related protein" ; rdfs:comment "A protein that is a translation product of the human INSRR gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:CHEBI_74634 a rdfs:Class ; rdfs:label "cardenolides" ; rdfs:comment "Any steroid lactone that is a C23 steroid with a five-membered lactone ring at C-17 and its substituted derivatives. They form the aglycone constituents of cardiac glycosides." ; rdfs:subClassOf obo:CHEBI_26766 , obo:CHEBI_50523 . obo:CHEBI_26907 a rdfs:Class ; rdfs:label "tetrahydrofolic acid" ; rdfs:comment "A group of heterocyclic compounds based on the 5,6,7,8-tetrahydropteroic acid skeleton conjugated with one or more L-glutamic acid units." ; rdfs:subClassOf obo:CHEBI_37445 . obo:CIDO_0000744 a rdfs:Class ; rdfs:label "T265I in SARS-CoV-2 pp1a protein"@en ; rdfs:comment "An AA mutation or AA variant that has mutated an amino acid at position 265 into a isoleucine in pp1a." ; rdfs:subClassOf obo:CIDO_0001073 . obo:CIDO_0000600 a rdf:Property ; rdfs:label "is AA variant of"@en ; rdfs:comment "An object property that defines a relation between an AA variant and a microbe variant where the microbe (like SARS_CoV-2) variant has the AA variant such that the microbe variant changes its AA from a previous one to a new one." ; rdfs:range . obo:CHEBI_33405 a rdfs:Class ; rdfs:label "hydracid" ; rdfs:comment "A hydracid is a compound which contains hydrogen that is not bound to oxygen, and which produces a conjugate base by loss of positive hydrogen ion(s) (hydrons)." ; rdfs:subClassOf obo:CHEBI_33608 . obo:NCBITaxon_903627 a rdfs:Class ; rdfs:label "Kenya bat coronavirus BtKY89" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:DOID_2030 a rdfs:Class ; rdfs:label "anxiety disorder" ; rdfs:comment "A cognitive disorder that involves an excessive, irrational dread of everyday situations." ; rdfs:subClassOf obo:DOID_1561 . obo:GO_0008610 a rdfs:Class ; rdfs:label "lipid biosynthetic process" ; rdfs:comment "The chemical reactions and pathways resulting in the formation of lipids, compounds soluble in an organic solvent but not, or sparingly, in an aqueous solvent." ; rdfs:subClassOf obo:GO_0006629 , obo:GO_1901576 . a rdfs:Class ; rdfs:label "Herpesviridae Infections [Disease/Finding]" ; rdfs:subClassOf . obo:NCBITaxon_1788474 a rdfs:Class ; rdfs:label "Miniopterus bat coronavirus BtCoV/4023-2" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:NCBITaxon_169418 a rdfs:Class ; rdfs:label "Mustelinae" ; rdfs:subClassOf obo:NCBITaxon_9655 . obo:CIDO_0000048 a rdfs:Class ; rdfs:label "SARS-CoV-2 Nsp6 protein interaction with host protein"@en ; rdfs:comment "A molecular interaction that has participant of the SARS-CoV-2 Nsp6 protein and a host protein" ; rdfs:subClassOf obo:CIDO_0000348 . obo:GO_0018958 a rdfs:Class ; rdfs:label "phenol-containing compound metabolic process" ; rdfs:comment "The chemical reactions and pathways involving a phenol, any compound containing one or more hydroxyl groups directly attached to an aromatic carbon ring." ; rdfs:subClassOf obo:GO_0006725 , obo:GO_0071704 , obo:GO_1901360 . obo:NCBITaxon_1245464 a rdfs:Class ; rdfs:label "Guinea fowl coronavirus GfCoV/FR/2011" ; rdfs:subClassOf obo:NCBITaxon_749416 . obo:PR_000050268 a rdfs:Class ; rdfs:label "spike protein S2 (SARS-CoV-2)" ; rdfs:comment "A spike glycoprotein, signal peptide removed form (SARS-CoV-2) that has been processed by proteolytic cleavage to yield the C-terminal portion. UniProtKB:P0DTC2, 686-1273." ; rdfs:subClassOf obo:PR_000050266 . obo:CIDO_0000410 a rdf:Property ; rdfs:label "has epitope cross-reactivity"@en ; rdfs:comment "A relation between two chemical entities X and Y such that if a portion of X is an epitope that binds to some antigen, there is also a portion of Y that is also an epitope which will bind to the same antigen." ; rdfs:range . a rdf:Property ; rdfs:range . a rdf:Property ; rdfs:range . a rdf:Property ; rdfs:range . a rdf:Property ; rdfs:range . obo:RO_0002436 a rdf:Property ; rdfs:label "molecularly interacts with" ; rdfs:comment "An interaction relationship in which the two partners are molecular entities that directly physically interact with each other for example via a stable binding interaction or a brief interaction during which one modifies the other." ; rdfs:seeAlso obo:ECO_0000353 ; rdfs:range ; rdfs:subPropertyOf obo:RO_0002434 . obo:CIDO_0000386 a rdf:Property ; rdfs:label "capable of binding to"@en ; rdfs:range ; rdfs:subPropertyOf obo:CIDO_0000385 . a rdf:Property ; rdfs:range . obo:NCBITaxon_6072 a rdfs:Class ; rdfs:label "Eumetazoa" ; rdfs:subClassOf obo:NCBITaxon_33208 . obo:NCBITaxon_1379866 a rdfs:Class ; rdfs:label "Bat coronavirus M.rufus28/Brazil/2010" ; rdfs:subClassOf obo:NCBITaxon_366617 . obo:NCBITaxon_1868641 a rdfs:Class ; rdfs:label "Bat coronavirus/5026/2013/Cynomops abrasus/Brazil" ; rdfs:subClassOf obo:NCBITaxon_366617 . obo:PR_000012245 a rdfs:Class ; rdfs:label "serine/threonine-protein kinase PAK 5" ; rdfs:comment "A protein that is a translation product of the human PAK5 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:CHEBI_78017 a rdfs:Class ; rdfs:label "food propellant" ; rdfs:comment "A propellant that is used to expel foods from an aerosol container." ; rdfs:subClassOf obo:CHEBI_64047 , obo:CHEBI_76414 . obo:PR_000015746 a rdfs:Class ; rdfs:label "serine/threonine-protein kinase 3" ; rdfs:comment "A protein that is a translation product of the human STK3 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:CIDO_0000067 a rdfs:Class ; rdfs:label "chemical role against viral entry"@en ; rdfs:subClassOf obo:CIDO_0000066 . obo:CHEBI_35623 a rdfs:Class ; rdfs:label "anticonvulsant" ; rdfs:comment "A drug used to prevent seizures or reduce their severity." ; rdfs:subClassOf obo:CHEBI_35488 . obo:CHEBI_33457 a rdfs:Class ; rdfs:label "phosphorus oxoacid" ; rdfs:comment "A pnictogen oxoacid which contains phosphorus and oxygen, at least one hydrogen atom bound to oxygen, and forms an ion by the loss of one or more protons." ; rdfs:subClassOf obo:CHEBI_33408 , obo:CHEBI_36360 . obo:NCBITaxon_384340 a rdfs:Class ; rdfs:label "Human coronavirus NO/1917/04" ; rdfs:subClassOf obo:NCBITaxon_384335 . obo:CIDO_0001217 a rdfs:Class ; rdfs:label "Multiple Real-Time PCR Kit for Detection of 2019-nCoV. (Shenzhen United Medical Technology Co., Ltd.)" ; rdfs:comment "Manufacturor: Shenzhen United Medical Technology Co., Ltd. 深圳联合医学科技有限公司" ; rdfs:subClassOf obo:CIDO_0000021 . obo:PR_000011390 a rdfs:Class ; rdfs:label "nuclear receptor subfamily 0 group B member 1" ; rdfs:comment "A protein that is a translation product of the human NR0B1 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:OAE_0001797 a rdfs:Class ; rdfs:label "psychiatric disorder AE" ; rdfs:comment "a behavior and neurological AE that has an outcome of a mental illness or psychiatiric disorder. The mental illness is a mental or behavioral pattern or anomaly that causes either suffering or an impaired ability to function in ordinary life (disability), and which is not developmentally or socially normative." ; rdfs:subClassOf obo:OAE_0000580 . obo:CIDO_0000240 a rdfs:Class ; rdfs:label "RG203KR in SARS-CoV-2 N protein"@en ; rdfs:comment "An aa-changing SNP triplet GGG28881AAC that occurs in a Nucleocapsid protein of a SARS-CoV-2 virus.It is a signature variant of SARS-CoV-2 clade GR." ; rdfs:subClassOf obo:CIDO_0000597 . obo:CHEBI_25693 a rdfs:Class ; rdfs:label "organic heteromonocyclic compound" ; rdfs:subClassOf obo:CHEBI_24532 , obo:CHEBI_33670 . obo:CHEBI_32624 a rdfs:Class ; rdfs:label "D-leucinium" ; rdfs:comment "The D-enantiomer of leucinium." ; rdfs:subClassOf obo:CHEBI_32628 . obo:CHEBI_84735 a rdfs:Class ; rdfs:label "algal metabolite" ; rdfs:comment "Any eukaryotic metabolite produced during a metabolic reaction in algae including unicellular organisms like chlorella and diatoms to multicellular organisms like giant kelps and brown algae." ; rdfs:subClassOf obo:CHEBI_75763 . obo:CIDO_0000761 a rdfs:Class ; rdfs:label "SARS-CoV2 M protein binding to human PMPCA" ; rdfs:comment "SARS-CoV2 M protein binding to human PMPCA, as evidented by an affinity-purification mass spectrometry experiment" ; rdfs:subClassOf obo:CIDO_0000055 . obo:CHEBI_22728 a rdfs:Class ; rdfs:label "benzopyrrole" ; rdfs:subClassOf obo:CHEBI_27171 , obo:CHEBI_38101 , obo:CHEBI_38180 . a rdfs:Class ; rdfs:label "Interferon Alfa-2a [Chemical/Ingredient]" ; rdfs:subClassOf , . obo:PR_000029126 a rdfs:Class ; rdfs:label "myosin light chain kinase 3" ; rdfs:comment "A protein that is a translation product of the human MYLK3 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:CHEBI_17137 a rdfs:Class ; rdfs:label "hydrogensulfite" ; rdfs:subClassOf obo:CHEBI_33482 . a rdfs:Class ; rdfs:label "METHYLPREDNISOLONE" ; rdfs:subClassOf . a rdf:Property ; rdfs:label "site_of_metabolism" ; rdfs:domain ; rdfs:range . a rdf:Property ; rdfs:label "CI_ChemClass" ; rdfs:domain ; rdfs:range . a rdf:Property ; rdfs:label "may_prevent" ; rdfs:domain ; rdfs:range . a rdf:Property ; rdfs:label "CI_PE" ; rdfs:domain ; rdfs:range . a rdf:Property ; rdfs:label "CI_MoA" ; rdfs:domain ; rdfs:range . a rdf:Property ; rdfs:label "CI_with" ; rdfs:domain ; rdfs:range . a rdf:Property ; rdfs:label "has_MoA" ; rdfs:domain ; rdfs:range . a rdf:Property ; rdfs:label "has_PK" ; rdfs:domain ; rdfs:range . a rdf:Property ; rdfs:label "has_Ingredient" ; rdfs:domain ; rdfs:range . a rdf:Property ; rdfs:label "may_treat" ; rdfs:domain ; rdfs:range . a rdf:Property ; rdfs:label "has_PE" ; rdfs:domain ; rdfs:range . obo:CHEBI_82979 a rdfs:Class ; rdfs:label "1-(4-{[2-(2,4-dichlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy}phenyl)-4-isopropylpiperazine" ; rdfs:comment "A dioxolane that is 1,3-dioxolane which is substituted at positions 2, 2, and 4 by 2,4-dichlorophenyl, 1H-1,2,4-triazol-1-ylmethyl, and [4-(4-isopropylpiperazin-1-yl)phenoxy]methyl groups, respectively." ; rdfs:subClassOf obo:CHEBI_23697 , obo:CHEBI_35618 , obo:CHEBI_35727 , obo:CHEBI_39430 , obo:CHEBI_46845 , obo:CHEBI_46848 , obo:CHEBI_59779 . obo:IDO_0000436 a rdfs:Class ; rdfs:label "infectious disease"@en ; rdfs:comment "A disease whose physical basis is an infectious disorder."@en ; rdfs:subClassOf obo:OGMS_0000031 . obo:NCBITaxon_11121 a rdfs:Class ; rdfs:label "Avian infectious bronchitis virus (strain 6/82)" ; rdfs:subClassOf obo:NCBITaxon_11120 . obo:HP_0002360 a rdfs:Class ; rdfs:label "Sleep disturbance" ; rdfs:comment "An abnormality of sleep including such phenomena as 1) insomnia/hypersomnia, 2) non-restorative sleep, 3) sleep schedule disorder, 4) excessive daytime somnolence, 5) sleep apnea, and 6) restlessness." ; rdfs:subClassOf obo:HP_0000708 . obo:OPMI_0000541 a rdfs:Class ; rdfs:label "preoperative diagnosis status"@en ; rdfs:comment "A preoperative diagnosis is a surgical diagnosis or diagnoses that are assigned to the patient before the surgical procedure, and is the reason for the surgery. A preoperative diagnosis is, in the opinion of the surgeon, the diagnosis that will be confirmed during surgery." ; rdfs:subClassOf obo:OPMI_0000533 . obo:GO_0051584 a rdfs:Class ; rdfs:label "regulation of dopamine uptake involved in synaptic transmission" ; rdfs:comment "Any process that modulates the frequency, rate or extent of the directed movement of the catecholamine neurotransmitter dopamine into a cell." ; rdfs:subClassOf obo:GO_0051049 , obo:GO_0051940 . obo:OPMI_0000532 a rdfs:Class ; rdfs:label "condition start datetime"@en ; rdfs:comment "The date and time on which a condition starts." ; rdfs:subClassOf obo:OPMI_0000528 . obo:BFO_0000157 a rdf:Property ; rdfs:label "during which exists"@en ; rdfs:domain obo:BFO_0000008 ; rdfs:range obo:BFO_0000001 . obo:BFO_0000154 a rdf:Property ; rdfs:label "temporal projection of spatiotemporal"@en ; rdfs:domain obo:BFO_0000008 ; rdfs:range obo:BFO_0000011 ; rdfs:subPropertyOf obo:BFO_0000157 . obo:BFO_0000156 a rdf:Property ; rdfs:label "has temporal occupant"@en ; rdfs:domain obo:BFO_0000008 ; rdfs:range obo:BFO_0000003 ; rdfs:subPropertyOf obo:BFO_0000157 . obo:CIDO_0000441 a rdfs:Class ; rdfs:label "HCoV OC43 protein"@en ; rdfs:subClassOf obo:CIDO_0000440 , obo:PR_000000001 . obo:PR_Q66GS9 a rdfs:Class ; rdfs:label "centrosomal protein of 135 kDa (human)" ; rdfs:comment "A centrosomal protein of 135 kDa that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000005341 , obo:PR_000029067 . obo:NCBITaxon_1699342 a rdfs:Class ; rdfs:label "Myotis Bat Alphacoronavirus strain YNXY_47C" ; rdfs:subClassOf obo:NCBITaxon_366617 . obo:CIDO_0000193 a rdfs:Class ; rdfs:label "coronaviral inhibition of host response"@en ; rdfs:subClassOf obo:CIDO_0000198 . obo:NCBITaxon_1649336 a rdfs:Class ; rdfs:label "Pigeon-dominant Coronavirus" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:PR_Q9H173 a rdfs:Class ; rdfs:label "nucleotide exchange factor SIL1 (human)" ; rdfs:comment "A nucleotide exchange factor SIL1 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000014873 , obo:PR_000029067 . obo:NCBITaxon_2042555 a rdfs:Class ; rdfs:label "Coronavirus PREDICT CoV-29" ; rdfs:subClassOf obo:NCBITaxon_366617 . obo:PR_000003426 a rdfs:Class ; rdfs:label "HSPA protein" ; rdfs:comment "An Hsp70 family chaperone that has its ATP-binding and substrate-binding domains separated by a linker domain of fewer than 25 amino acids." ; rdfs:subClassOf obo:PR_000003425 . obo:CIDO_0020279 a rdfs:Class ; rdfs:label "SARS-COV-2 R-GENE" ; rdfs:seeAlso ; rdfs:subClassOf obo:CIDO_0000454 . a rdfs:Class ; rdfs:label "Hydroxychloroquine Sulfate [Chemical/Ingredient]" ; rdfs:subClassOf . obo:NCBITaxon_233262 a rdfs:Class ; rdfs:label "Bovine enteric coronavirus (strain 98TXSF-110-ENT)" ; rdfs:subClassOf obo:NCBITaxon_11128 . obo:PR_Q13470 a rdfs:Class ; rdfs:label "non-receptor tyrosine-protein kinase TNK1 (human)" ; rdfs:comment "A non-receptor tyrosine-protein kinase TNK1 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000016495 , obo:PR_000029067 . obo:CHEBI_44369 a rdfs:Class ; rdfs:label "duvoglustat" ; rdfs:comment "An optically active form of 2-(hydroxymethyl)piperidine-3,4,5-triol having 2R,3R,4R,5S-configuration." ; rdfs:subClassOf obo:CHEBI_26147 , obo:CHEBI_72490 . obo:NCBITaxon_1788480 a rdfs:Class ; rdfs:label "Miniopterus bat coronavirus BtCoV/4056-2" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:CIDO_0000847 a rdfs:Class ; rdfs:label "SARS-CoV2 nsp13 protein binding to human JAKMIP1" ; rdfs:comment "SARS-CoV2 nsp13 protein binding to human JAKMIP1, as evidented by an affinity-purification mass spectrometry experiment" ; rdfs:subClassOf obo:CIDO_0000058 . obo:PR_000013015 a rdfs:Class ; rdfs:label "pro-opiomelanocortin" ; rdfs:comment "A protein that is a translation product of the human POMC gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:NCBITaxon_1788491 a rdfs:Class ; rdfs:label "Rhinolophus bat coronavirus BtCoV/4017-2" ; rdfs:subClassOf obo:NCBITaxon_2664420 . a rdfs:Class ; rdfs:label "Corticosteroid Hormone Receptor Agonists [MoA]" ; rdfs:subClassOf . obo:CIDO_0000092 a rdfs:Class ; rdfs:label "MERS-CoV entry to cell"@en ; rdfs:comment "A coronavirus-host interaction by which the MERS-CoV virus enters the host cell" ; rdfs:subClassOf obo:CIDO_0000085 . obo:PR_Q13206 a rdfs:Class ; rdfs:label "probable ATP-dependent RNA helicase DDX10 (human)" ; rdfs:comment "A probable ATP-dependent RNA helicase DDX10 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000029067 , obo:PR_000029381 . obo:CIDO_0000520 a rdfs:Class ; rdfs:label "WNGVIKNVNSVRDWL" ; rdfs:comment "A coronavirus epitope that is part of some S protein from HCoV 229E composed of the following amino acids WNGVIKNVNSVRDWL" ; rdfs:subClassOf obo:CIDO_0000451 . obo:CHEBI_189683 a rdfs:Class ; rdfs:label "sigma receptor modulator" ; rdfs:comment "Any receptor modulator acting on sigma receptors." ; rdfs:subClassOf obo:CHEBI_90710 . obo:NCBITaxon_741997 a rdfs:Class ; rdfs:label "Bat SARS coronavirus HKU3-10" ; rdfs:subClassOf obo:NCBITaxon_442736 . obo:CHEBI_53339 a rdfs:Class ; rdfs:label "olefinic fatty acid" ; rdfs:comment "Any fatty acid containing at least one C=C double bond." ; rdfs:subClassOf obo:CHEBI_27208 , obo:CHEBI_78840 . obo:CIDO_0001073 a rdfs:Class ; rdfs:label "AA variant in SARS-CoV-2 nsp2 protein"@en ; rdfs:comment "An AA variant in SARS-CoV-2 nsp2 protein. Equivalent to an AA variant in SARS-CoV-2 rep 1ab with an AA position of 181 - 818." ; rdfs:subClassOf obo:CIDO_0000714 . a rdfs:Class ; rdfs:label "Transcription Factor Activity [MoA]" ; rdfs:subClassOf . obo:NCBITaxon_1699351 a rdfs:Class ; rdfs:label "Rousettus Bat Betacoronavirus ML_56I" ; rdfs:subClassOf obo:NCBITaxon_696098 . obo:DOID_74 a rdfs:Class ; rdfs:label "hematopoietic system disease" ; rdfs:comment "A disease of anatomical entity that has_material_basis_in hematopoietic cells." ; rdfs:subClassOf obo:DOID_7 . obo:CIDO_0001228 a rdfs:Class ; rdfs:label "Multiple Real-Time PCR Kit for Detection of 2019-nCoV. (Chaozhou Hybribio Biochemistry Ltd.)" ; rdfs:comment "Registration ID: NMPA 20213400269" ; rdfs:subClassOf obo:CIDO_0000021 . obo:PATO_0001421 a rdfs:Class ; rdfs:label "alive" ; rdfs:comment "A viability quality inhering in a bearer by virtue of the bearer's condition before death." ; rdfs:subClassOf obo:PATO_0000169 . a rdfs:Class ; rdfs:label "Consciousness Disorders [Disease/Finding]" ; rdfs:subClassOf , . obo:CHEBI_87039 a rdfs:Class ; rdfs:label "bridged diphenyl fungicide" ; rdfs:comment "Any organic aromatic compound containing two phenyl (or substituted phenyl) groups attached to a single carbon or heteroatom and which has been used as a fungicide." ; rdfs:subClassOf obo:CHEBI_33659 , obo:CHEBI_60644 . obo:IAO_0000009 a rdfs:Class ; rdfs:label "data item label"@en ; rdfs:comment "A label is a symbol that is part of some other datum and is used to either partially define the denotation of that datum or to provide a means for identifying the datum as a member of the set of data with the same label"@en ; rdfs:subClassOf obo:IAO_0000030 . obo:HP_0000708 a rdfs:Class ; rdfs:label "Behavioral abnormality" ; rdfs:comment "An abnormality of mental functioning including various affective, behavioural, cognitive and perceptual abnormalities." ; rdfs:subClassOf obo:HP_0012638 . obo:PR_000009199 a rdfs:Class ; rdfs:label "Janus kinase and microtubule-interacting protein 1" ; rdfs:comment "A protein that is a translation product of the human JAKMIP1 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:HP_0001254 a rdfs:Class ; rdfs:label "Lethargy" ; rdfs:comment "A state of disinterestedness, listlessness, and indifference, resulting in difficulty performing simple tasks or concentrating." ; rdfs:subClassOf obo:HP_0004372 . obo:NCBITaxon_693996 a rdfs:Class ; rdfs:label "Alphacoronavirus" ; rdfs:subClassOf obo:NCBITaxon_2501931 . obo:OGG_3000003606 a rdfs:Class ; rdfs:label "IL18" ; rdfs:comment "Other designations: IFN-gamma-inducing factor|IL-1 gamma|iboctadekin|interleukin 18 (interferon-gamma-inducing factor)|interleukin-1 gamma|interleukin-18" ; rdfs:subClassOf obo:OGG_2060009606 . obo:BFO_0000162 a rdf:Property ; rdfs:label "has disposition at all times"@en ; rdfs:comment "a has_disposition b at t =Def. b disposition_of a at t. (axiom label in BFO2 Reference: [069-001])"@en ; rdfs:range obo:BFO_0000020 ; rdfs:subPropertyOf obo:BFO_0000158 . obo:CIDO_0000299 a rdf:Property ; rdfs:label "gene susceptibly up-regulated in organism"@en ; rdfs:comment "An object property that represents a relation between a gene and an organism where the gene is susceptibly up-regulated in the organism." ; rdfs:range . obo:NCBITaxon_931911 a rdfs:Class ; rdfs:label "Alphacoronavirus Eptesicus fuscus/Appalachian Ridge/P1-C265/IT/USA/2009" ; rdfs:subClassOf obo:NCBITaxon_366617 . obo:OAE_0000375 a rdfs:Class ; rdfs:label "myalgia AE" ; rdfs:comment "a pain AE that has outcome of myalgia. Myalgia means \"muscle pain\" and is a symptom of many diseases and disorders." ; rdfs:subClassOf obo:OAE_0000374 . obo:PR_Q9UHA3 a rdfs:Class ; rdfs:label "probable ribosome biogenesis protein RLP24 (human)" ; rdfs:comment "A probable ribosome biogenesis protein RLP24 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000029067 , obo:PR_000030281 . obo:PR_000050275 a rdfs:Class ; rdfs:label "non-structural protein 6 (SARS-CoV-2)" ; rdfs:comment "A rep gene proteolytic cleavage product (SARS-CoV-2) that is the central portion produced by the enzymatic action of 3CL-PRO proteinase (nsp5) when it cleaves the precursor rep gene translation product (SARS-CoV-2) between residues 3569-3570 and 3859-3860." ; rdfs:subClassOf obo:PR_000050281 . obo:PR_000029886 a rdfs:Class ; rdfs:label "zinc finger CCCH domain-containing protein 18" ; rdfs:comment "A protein that is a translation product of the human ZC3H18 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . a rdfs:Class ; rdfs:label "Hematopoiesis Alteration [PE]" ; rdfs:subClassOf . obo:CIDO_0020090 a rdfs:Class ; rdfs:label "COV-19 IDx assay" ; rdfs:seeAlso ; rdfs:subClassOf obo:CIDO_0000454 . obo:CHEBI_22928 a rdfs:Class ; rdfs:label "bromine molecular entity" ; rdfs:subClassOf obo:CHEBI_24471 . obo:PR_P13637 a rdfs:Class ; rdfs:label "sodium/potassium-transporting ATPase subunit alpha-3 (human)" ; rdfs:comment "A sodium/potassium-transporting ATPase subunit alpha-3 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000004437 , obo:PR_000029067 . a rdfs:Class ; rdfs:label "Enzyme Inhibitors [MoA]" ; rdfs:subClassOf . obo:CIDO_0000825 a rdfs:Class ; rdfs:label "SARS-CoV2 nsp13 protein binding to human CDK5RAP2" ; rdfs:comment "SARS-CoV2 nsp13 protein binding to human CDK5RAP2, as evidented by an affinity-purification mass spectrometry experiment" ; rdfs:subClassOf obo:CIDO_0000058 . a rdfs:Class ; rdfs:label "Demyelinating Autoimmune Diseases, CNS [Disease/Finding]" ; rdfs:subClassOf , , . obo:HP_0007200 a rdfs:Class ; rdfs:label "Episodic hypersomnia" ; rdfs:subClassOf obo:HP_0004372 , obo:HP_0100786 . a rdfs:Class ; rdfs:label "C [Preparations]" ; rdfs:subClassOf . a rdfs:Class ; rdfs:label "Lymphoma, T-Cell, Cutaneous [Disease/Finding]" ; rdfs:subClassOf . obo:PR_000013160 a rdfs:Class ; rdfs:label "palmitoyl-protein thioesterase 1" ; rdfs:comment "A protein that is a translation product of the human PPT1 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:GO_0055080 a rdfs:Class ; rdfs:label "cation homeostasis" ; rdfs:comment "Any process involved in the maintenance of an internal steady state of cations within an organism or cell." ; rdfs:subClassOf obo:GO_0050801 . obo:GO_0070727 a rdfs:Class ; rdfs:label "cellular macromolecule localization" ; rdfs:comment "Any process in which a macromolecule is transported to, and/or maintained in, a specific location at the level of a cell. Localization at the cellular level encompasses movement within the cell, from within the cell to the cell surface, or from one location to another at the surface of a cell." ; rdfs:subClassOf obo:GO_0033036 , obo:GO_0051641 . obo:PR_000010126 a rdfs:Class ; rdfs:label "dual specificity mitogen-activated protein kinase kinase 2" ; rdfs:comment "A protein that is a translation product of the human MAP2K2 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . a rdfs:Class ; rdfs:label "Congenital, Hereditary, and Neonatal Diseases and Abnormalities [Disease/Finding]" ; rdfs:subClassOf . obo:CIDO_0000777 a rdfs:Class ; rdfs:label "SARS-CoV2 N protein binding to human CSNK2B" ; rdfs:comment "SARS-CoV2 N protein binding to human CSNK2B, as evidented by an affinity-purification mass spectrometry experiment" ; rdfs:subClassOf obo:CIDO_0000056 . obo:PR_000012791 a rdfs:Class ; rdfs:label "plakophilin-2" ; rdfs:comment "A protein that is a translation product of the human PKP2 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:CHEBI_76967 a rdfs:Class ; rdfs:label "human xenobiotic metabolite" ; rdfs:comment "Any human metabolite produced by metabolism of a xenobiotic compound in humans." ; rdfs:subClassOf obo:CHEBI_76206 , obo:CHEBI_77746 . obo:CHEBI_35674 a rdfs:Class ; rdfs:label "antihypertensive agent" ; rdfs:comment "Any drug used in the treatment of acute or chronic vascular hypertension regardless of pharmacological mechanism." ; rdfs:subClassOf obo:CHEBI_35554 . obo:CIDO_0020231 a rdfs:Class ; rdfs:label "PCL SARS-CoV-2 Real-Time RT-PCR Assay" ; rdfs:seeAlso ; rdfs:subClassOf obo:CIDO_0000454 . obo:PR_000001393 a rdfs:Class ; rdfs:label "interleukin-6" ; rdfs:comment "A protein that is a translation product of the human IL6 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:NCBITaxon_424368 a rdfs:Class ; rdfs:label "Bat coronavirus HKU9-2" ; rdfs:subClassOf obo:NCBITaxon_694006 . obo:NCBITaxon_749420 a rdfs:Class ; rdfs:label "Black-headed gull coronavirus CIR-66183" ; rdfs:subClassOf obo:NCBITaxon_749416 . obo:PR_O15393 a rdfs:Class ; rdfs:label "transmembrane protease serine 2 (human)" ; rdfs:comment "A transmembrane protease serine 2 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000016456 , obo:PR_000029067 . obo:CIDO_0000189 a rdf:Property ; rdfs:label "capable of priming activity of"@en ; rdfs:comment "An object property between material entity a and b where a is capable of priming the activity of b" ; rdfs:range ; rdfs:subPropertyOf obo:RO_0002410 . obo:CHEBI_38443 a rdfs:Class ; rdfs:label "1-benzopyran" ; rdfs:subClassOf obo:CHEBI_22727 . obo:CHEBI_45409 a rdfs:Class ; rdfs:label "ritonavir" ; rdfs:comment "An L-valine derivative that is L-valinamide in which alpha-amino group has been acylated by a [(2-isopropyl-1,3-thiazol-4-yl)methyl]methylcarbamoyl group and in which a hydrogen of the carboxamide amino group has been replaced by a (2R,4S,5S)-4-hydroxy-1,6-diphenyl-5-{[(1,3-thiazol-5-ylmethoxy)carbonyl]amino}hexan-2-yl group. A CYP3A inhibitor and antiretroviral drug from the protease inhibitor class used to treat HIV infection and AIDS, it is often used as a fixed-dose combination with another protease inhibitor, lopinavir. Also used in combination with dasabuvir sodium hydrate, ombitasvir and paritaprevir (under the trade name Viekira Pak) for treatment of chronic hepatitis C virus genotype 1 infection as well as cirrhosis of the liver." ; rdfs:subClassOf obo:CHEBI_23003 , obo:CHEBI_27267 , obo:CHEBI_37622 , obo:CHEBI_38418 , obo:CHEBI_47857 , obo:CHEBI_84129 . obo:CIDO_0000140 a rdf:Property ; rdfs:label "chemical inhibits in vivo replication of virus"@en ; rdfs:comment "An object property that represents a relation between a chemical entity and a virus where the chemical has an effective role against viral replication in vivo" ; rdfs:range ; rdfs:subPropertyOf obo:CIDO_0000150 , obo:CIDO_0000142 . obo:CIDO_0000287 a rdfs:Class ; rdfs:label "SARS-CoV-2 shedding"@en ; rdfs:subClassOf obo:CIDO_0000197 , obo:CIDO_0000202 , obo:CIDO_0000286 . obo:CHEBI_79020 a rdfs:Class ; rdfs:label "alpha,beta-unsaturated monocarboxylic acid" ; rdfs:comment "A monocarboxylic acid in which the carbon of the carboxy group is directly attached to a C=C or C#C bond." ; rdfs:subClassOf obo:CHEBI_25384 . obo:PR_000003599 a rdfs:Class ; rdfs:label "complex I assembly factor ACAD9, mitochondrial" ; rdfs:comment "A protein that is a translation product of the human ACAD9 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:CHEBI_72695 a rdfs:Class ; rdfs:label "organic molecule" ; rdfs:comment "Any molecule that consists of at least one carbon atom as part of the electrically neutral entity." ; rdfs:subClassOf obo:CHEBI_25367 , obo:CHEBI_50860 . obo:PR_P49069 a rdfs:Class ; rdfs:label "guided entry of tail-anchored proteins factor CAMLG (human)" ; rdfs:comment "A guided entry of tail-anchored proteins factor CAMLG that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000004997 , obo:PR_000029067 . obo:CHEBI_18407 a rdfs:Class ; rdfs:label "hydrogen cyanide" ; rdfs:comment "A one-carbon compound consisting of a methine group triple bonded to a nitrogen atom" ; rdfs:subClassOf obo:CHEBI_33405 , obo:CHEBI_64708 . obo:CHEBI_84129 a rdfs:Class ; rdfs:label "L-valine derivative" ; rdfs:comment "A proteinogenic amino acid derivative resulting from reaction of L-valine at the amino group or the carboxy group, or from the replacement of any hydrogen of L-valine by a heteroatom." ; rdfs:subClassOf obo:CHEBI_27267 , obo:CHEBI_83811 . obo:NCBITaxon_389155 a rdfs:Class ; rdfs:label "Bat coronavirus (BtCoV/A905/2005)" ; rdfs:subClassOf obo:NCBITaxon_389126 . obo:CIDO_0020283 a rdfs:Class ; rdfs:label "SARS-CoV-2-Assay" ; rdfs:seeAlso ; rdfs:subClassOf obo:CIDO_0000454 . obo:CHEBI_15640 a rdfs:Class ; rdfs:label "5-formyltetrahydrofolic acid" ; rdfs:comment "A formyltetrahydrofolic acid in which the formyl group is located at position 5." ; rdfs:subClassOf obo:CHEBI_24099 . obo:CIDO_0000889 a rdfs:Class ; rdfs:label "SARS-CoV2 nsp6 protein binding to human ATP6AP1" ; rdfs:comment "SARS-CoV2 nsp6 protein binding to human ATP6AP1, as evidented by an affinity-purification mass spectrometry experiment" ; rdfs:subClassOf obo:CIDO_0000048 . obo:NCBITaxon_497939 a rdfs:Class ; rdfs:label "Bat coronavirus M.das/Germany/D3.38/2007" ; rdfs:subClassOf obo:NCBITaxon_366617 . obo:NCBITaxon_694002 a rdfs:Class ; rdfs:label "Betacoronavirus" ; rdfs:subClassOf obo:NCBITaxon_2501931 . obo:GO_0002035 a rdfs:Class ; rdfs:label "brain renin-angiotensin system" ; rdfs:comment "The process in which an angiotensin-mediated signaling system present in the brain regulates the force with which blood passes through the circulatory system." ; rdfs:subClassOf obo:GO_0002016 , obo:GO_0050877 . obo:CHEBI_33848 a rdfs:Class ; rdfs:label "polycyclic arene" ; rdfs:comment "A polycyclic aromatic hydrocarbon." ; rdfs:subClassOf obo:CHEBI_33658 , obo:CHEBI_33666 . obo:DRON_00015446 a rdfs:Class ; rdfs:label "Ouabain" ; rdfs:subClassOf obo:OBI_0000047 . obo:CIDO_0000131 a rdf:Property ; rdfs:label "drug has protein target as inhibitor"@en ; rdfs:comment "An object property that represents a relation between a drug and a protein where the drug can target the protein as an enzyme inhibitor." ; rdfs:range ; rdfs:subPropertyOf obo:CIDO_0000124 . obo:NCBITaxon_1503298 a rdfs:Class ; rdfs:label "BtRf-BetaCoV/HuB2013" ; rdfs:subClassOf obo:NCBITaxon_696098 . obo:CHEBI_17987 a rdfs:Class ; rdfs:label "benzyl alcohol" ; rdfs:comment "An aromatic alcohol that consists of benzene bearing a single hydroxymethyl substituent." ; rdfs:subClassOf obo:CHEBI_22743 . obo:VO_0000145 a rdfs:Class ; rdfs:label "recombinant vaccine vector role" ; rdfs:comment "a vaccine component role that inheres in a recombinant vaccine vector as a vaccine component. The combination of a recombinant vaccine vector and a heterogenous protective antigen(s) inserted inside the vector for a recombinant vector vaccine. " ; rdfs:subClassOf obo:VO_0000617 . a rdfs:Class ; rdfs:label "Nevi and Melanomas [Disease/Finding]" ; rdfs:subClassOf . obo:PR_000040662 a rdfs:Class ; rdfs:label "cathepsin-like protease" ; rdfs:comment "A protein that is a translation product of some metazoan gene that encodes a signal peptide followed by a single Cathepsin propeptide inhibitor domain (Pfam:PF08246) followed by a single Papain family cysteine protease (Pfam:PF00112) domain at the C terminus." ; rdfs:subClassOf obo:PR_000036194 . obo:CHEBI_64152 a rdfs:Class ; rdfs:label "cysteine protease inhibitor" ; rdfs:comment "Any protease inhibitor that restricts the action of a cysteine protease." ; rdfs:subClassOf obo:CHEBI_37670 , obo:CHEBI_76796 . obo:NCBITaxon_1346291 a rdfs:Class ; rdfs:label "Betacoronavirus BtCoV/KCR15/Pte_par/CRC/2012" ; rdfs:subClassOf obo:NCBITaxon_696098 . obo:CIDO_0001055 a rdfs:Class ; rdfs:label "SARS-CoV2 orf9c protein binding to human NDFIP2" ; rdfs:comment "SARS-CoV2 orf9c protein binding to human NDFIP2, as evidented by an affinity-purification mass spectrometry experiment" ; rdfs:subClassOf obo:CIDO_0000054 . obo:PR_P09132 a rdfs:Class ; rdfs:label "signal recognition particle 19 kDa protein (human)" ; rdfs:comment "A signal recognition particle 19 kDa protein that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000015624 , obo:PR_000029067 . a rdfs:Class ; rdfs:label "Enterocolitis [Disease/Finding]" ; rdfs:subClassOf , . obo:CIDO_0000409 a rdfs:Class ; rdfs:label "obsolete term"@en ; rdfs:comment "A term that has been deprecated." . obo:PR_Q9H4P4 a rdfs:Class ; rdfs:label "E3 ubiquitin-protein ligase NRDP1 (human)" ; rdfs:comment "An E3 ubiquitin-protein ligase NRDP1 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000014136 , obo:PR_000029067 . obo:PR_Q86VM9 a rdfs:Class ; rdfs:label "zinc finger CCCH domain-containing protein 18 (human)" ; rdfs:comment "A zinc finger CCCH domain-containing protein 18 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000029067 , obo:PR_000029886 . obo:NCBITaxon_2050019 a rdfs:Class ; rdfs:label "Shrew coronavirus" ; rdfs:subClassOf obo:NCBITaxon_2730119 . obo:NCBITaxon_1346305 a rdfs:Class ; rdfs:label "Betacoronavirus BtCoV/Rhi_fer/It17/ITA/2009" ; rdfs:subClassOf obo:NCBITaxon_696098 . obo:CIDO_0000766 a rdfs:Class ; rdfs:label "SARS-CoV2 M protein binding to human RTN4" ; rdfs:comment "SARS-CoV2 M protein binding to human RTN4, as evidented by an affinity-purification mass spectrometry experiment" ; rdfs:subClassOf obo:CIDO_0000055 . a rdfs:Class ; rdfs:label "Decreased Peripheral Nervous System Norepinephrine Activity [PE]" ; rdfs:subClassOf . obo:NCBITaxon_11138 a rdfs:Class ; rdfs:label "Murine hepatitis virus" ; rdfs:subClassOf obo:NCBITaxon_694005 . obo:CIDO_0000202 a rdfs:Class ; rdfs:label "coronavirus shedding"@en ; rdfs:comment "A coronavirus process that involves in the release of the assemblied virion from the host cell" ; rdfs:subClassOf obo:CIDO_0000198 , obo:CIDO_0000285 , obo:GO_0019076 . obo:PR_O94826 a rdfs:Class ; rdfs:label "mitochondrial import receptor subunit TOM70 (human)" ; rdfs:comment "A mitochondrial import receptor subunit TOM70 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000016541 , obo:PR_000029067 . obo:PR_000010635 a rdfs:Class ; rdfs:label "28S ribosomal protein S27, mitochondrial" ; rdfs:comment "A protein that is a translation product of the human MRPS27 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:PR_Q9H2K8 a rdfs:Class ; rdfs:label "serine/threonine-protein kinase TAO3 (human)" ; rdfs:comment "A serine/threonine-protein kinase TAO3 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000016050 , obo:PR_000029067 . obo:PR_000002210 a rdfs:Class ; rdfs:label "protein kinase C, delta-like" ; rdfs:comment "A protein that is a translation product of the human PRKCD, PRKCE, PRKCH, or PRKCQ genes, or 1:1 orthologs thereof. The core domain architecture consists of a C2 domain (Pfam:PF00168), which is not always detected, two Phorbol esters/diacylglycerol binding domains (Pfam:PF00130, also called C1 domain), a Protein kinase domain (Pfam:PF00069), and a Protein kinase C terminal domain (Pfam:PF00433)." ; rdfs:subClassOf obo:PR_000000001 . obo:CHEBI_46926 a rdfs:Class ; rdfs:label "dioxanes" ; rdfs:subClassOf obo:CHEBI_25693 , obo:CHEBI_38104 . obo:CHEBI_76224 a rdfs:Class ; rdfs:label "aromatic ketone" ; rdfs:comment "A ketone in which the carbonyl group is attached to an aromatic ring." ; rdfs:subClassOf obo:CHEBI_17087 . obo:OBI_0002538 a rdfs:Class ; rdfs:label "cerebellum specimen" ; rdfs:comment "A specimen that is derived from cerebellum." ; rdfs:subClassOf obo:OBI_0001479 . obo:DRON_00023979 a rdfs:Class ; rdfs:label "Cyclosporine Injectable Solution" ; rdfs:subClassOf obo:DRON_00000020 . obo:CIDO_0000129 a rdf:Property ; rdfs:label "drug has protein target as binder"@en ; rdfs:comment "An object property that represents a relation between a drug and a protein where the drug can target the protein as an binder that chemically binds to the targeted protein." ; rdfs:range ; rdfs:subPropertyOf obo:CIDO_0000124 . obo:CIDO_0000130 a rdf:Property ; rdfs:label "drug has protein target as inducer"@en ; rdfs:comment "An object property that represents a relation between a drug and a protein where the drug can target the protein as an enzyme inducer. An enzyme inducer is a type of chemical that increases the metabolic activity of an enzyme either by binding to the enzyme and activating it, or by increasing the expression of the gene coding for the enzyme." ; rdfs:range ; rdfs:subPropertyOf obo:CIDO_0000124 . a rdfs:Class ; rdfs:label "Propylamines [Chemical/Ingredient]" ; rdfs:subClassOf . obo:NCBITaxon_1269303 a rdfs:Class ; rdfs:label "Coronavirus BtCoV/KCR252/Car_per/CRC/2010" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:CHEBI_35568 a rdfs:Class ; rdfs:label "mancude ring" ; rdfs:comment "Any molecular entity that consists of a ring having (formally) the maximum number of noncumulative double bonds." ; rdfs:subClassOf obo:CHEBI_23367 . obo:CIDO_0020229 a rdfs:Class ; rdfs:label "PacificDx Covid-19" ; rdfs:seeAlso ; rdfs:subClassOf obo:CIDO_0000454 . obo:PR_P51617 a rdfs:Class ; rdfs:label "interleukin-1 receptor-associated kinase 1 (human)" ; rdfs:comment "An interleukin-1 receptor-associated kinase 1 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000001782 , obo:PR_000029067 . obo:NCBITaxon_10088 a rdfs:Class ; rdfs:label "Mus " ; rdfs:subClassOf obo:NCBITaxon_39107 . a rdfs:Class ; rdfs:label "Digitalis Glycosides [Chemical/Ingredient]" ; rdfs:subClassOf . a rdfs:Class ; rdfs:label "Central Nervous System Infections [Disease/Finding]" ; rdfs:subClassOf , . obo:CHEBI_16040 a rdfs:Class ; rdfs:label "cytosine" ; rdfs:comment "An aminopyrimidine that is pyrimidin-2-one having the amino group located at position 4." ; rdfs:subClassOf obo:CHEBI_26432 , obo:CHEBI_38337 , obo:CHEBI_38338 . obo:CHEBI_32646 a rdfs:Class ; rdfs:label "methioninium" ; rdfs:comment "A sulfur-containing amino-acid anion that is the conjugate acid of methionine, arising from protonation of the amino group." ; rdfs:subClassOf obo:CHEBI_33719 . obo:PR_000008735 a rdfs:Class ; rdfs:label "hypoxanthine-guanine phosphoribosyltransferase" ; rdfs:comment "A protein that is a translation product of the human HPRT1 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:DRON_00750820 a rdfs:Class ; rdfs:label "oritavancin" ; rdfs:subClassOf obo:OBI_0000047 . obo:CHEBI_64209 a rdfs:Class ; rdfs:label "clomipramine(1+)" ; rdfs:comment "An ammonium ion resulting from the protonation of the dimethyl-substituted amino group of clomipramine." ; rdfs:subClassOf obo:CHEBI_25697 , obo:CHEBI_35274 . obo:CIDO_0000721 a rdfs:Class ; rdfs:label "E1092K in SARS-CoV-2 S protein"@en ; rdfs:comment "An AA mutation or AA variant that has mutated an amino acid at position 1092 into a glutamic acid in S protein." ; rdfs:subClassOf obo:CIDO_0001163 . obo:PR_P12823 a rdfs:Class ; rdfs:label "genome polyprotein (Dengue virus 2 Puerto Rico/PR159-S1/1969)" ; rdfs:comment "A dengue virus genome polyprotein that is encoded in the genome of Dengue virus 2 Puerto Rico/PR159-S1/1969." ; rdfs:subClassOf obo:PR_000036197 , obo:PR_000036816 . a rdfs:Class ; rdfs:label "Hormones [Chemical/Ingredient]" ; rdfs:subClassOf . obo:NCBITaxon_903605 a rdfs:Class ; rdfs:label "Kenya bat coronavirus BtKY67" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:CIDO_0001062 a rdfs:Class ; rdfs:label "SARS-CoV2 orf9c protein binding to human SCAP" ; rdfs:comment "SARS-CoV2 orf9c protein binding to human SCAP, as evidented by an affinity-purification mass spectrometry experiment" ; rdfs:subClassOf obo:CIDO_0000054 . obo:PR_000007920 a rdfs:Class ; rdfs:label "growth/differentiation factor 15" ; rdfs:comment "A protein that is a translation product of the human GDF15 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:GO_0043170 a rdfs:Class ; rdfs:label "macromolecule metabolic process" ; rdfs:comment "The chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass." ; rdfs:subClassOf obo:GO_0071704 . a rdfs:Class ; rdfs:label "Flavivirus Infections [Disease/Finding]" ; rdfs:subClassOf . obo:CIDO_0000959 a rdfs:Class ; rdfs:label "SARS-CoV2 nsp9 protein binding to human NUP62" ; rdfs:comment "SARS-CoV2 nsp9 protein binding to human NUP62, as evidented by an affinity-purification mass spectrometry experiment" ; rdfs:subClassOf obo:CIDO_0000583 . obo:OAE_0000398 a rdfs:Class ; rdfs:label "cough AE" ; rdfs:comment "an abnormal respiration AE that shows a sudden and often repetitively occurring reflex to keep the throat and airways clear" ; rdfs:subClassOf obo:OAE_0000571 . obo:CIDO_0000355 a rdfs:Class ; rdfs:label "ACE inhibitor role"@en ; rdfs:comment "A role taken by a chemcial entity that inhibits the activity of angiotensin-converting enzyme, an important component of the renin–angiotensin system which converts angiotensin I to angiotensin II, and hydrolyses bradykinin. ACE inhibitor drugs are used primarily for the treatment of high blood pressure and heart failure by causing relaxation of blood vessels as well as a decrease in blood volume, which leads to lower blood pressure and decreased oxygen demand from the heart." ; rdfs:subClassOf obo:BFO_0000023 . obo:VO_0005254 a rdfs:Class ; rdfs:label "SC-Ad6-1"@en ; rdfs:comment "A SARS-CoV-2 recombinant adenoviral vector vaccine by Tetherex Pharmaceutical Corporation" ; rdfs:subClassOf obo:VO_0005200 . obo:PR_000003582 a rdfs:Class ; rdfs:label "tyrosine-protein kinase ABL1" ; rdfs:comment "A protein that is a translation product of the human ABL1 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:VO_0011320 a rdfs:Class ; rdfs:label "S protein of SARS-CoV" ; rdfs:comment "The receptor-binding domain (RBD) of SARS-CoV spike (S) protein is an important target in developing safe and effective SARS vaccines. A previous study has demonstrated that vaccination with adeno-associated virus encoding RBD (RBD-rAAV) induces high titer of neutralizing antibodies. The immune responses and protective effect of the immunization with RBD-rAAV prime/RBD-specific T cell peptide boost were assessed. Compared with the RBD-rAAV prime/boost vaccination, RBD-rAAV prime/RBD-peptide (RBD-Pep) boost induced similar levels of Th1 and neutralizing antibody responses that protected the vaccinated mice from subsequent SARS-CoV challenge, but stronger Th2 and CTL responses. No significant immune responses and protective effects were detected in mice vaccinated with RBD-Pep or blank AAV alone [PubMed: 18289745]." ; rdfs:subClassOf obo:VO_0010850 . obo:CHEBI_51867 a rdfs:Class ; rdfs:label "methyl ketone" ; rdfs:comment "A ketone of formula RC(=O)CH3 (R =/= H)." ; rdfs:subClassOf obo:CHEBI_17087 . a rdfs:Class ; rdfs:label "Decreased Respiratory Secretions [PE]" ; rdfs:subClassOf . obo:APOLLO_SV_00000123 a rdfs:Class ; rdfs:label "school closure control strategy"@en ; rdfs:comment "A place closure control strategy whose action specification is realized in a school closure process."@en ; rdfs:subClassOf obo:APOLLO_SV_00000229 . obo:GO_0006644 a rdfs:Class ; rdfs:label "phospholipid metabolic process" ; rdfs:comment "The chemical reactions and pathways involving phospholipids, any lipid containing phosphoric acid as a mono- or diester." ; rdfs:subClassOf obo:GO_0006796 , obo:GO_0019637 , obo:GO_0044255 . obo:CHEBI_48819 a rdfs:Class ; rdfs:label "cyano group" ; rdfs:subClassOf obo:CHEBI_36823 . a rdf:Property ; rdfs:label "is substituent group from" ; rdfs:range . obo:OMRSE_00000002 a rdfs:Class ; rdfs:label "party to a legal entity"@en ; rdfs:subClassOf obo:OMRSE_00000024 . obo:RO_0000052 a rdf:Property ; rdfs:label "inheres in"@en ; rdfs:comment "a relation between a specifically dependent continuant (the dependent) and an independent continuant (the bearer), in which the dependent specifically depends on the bearer for its existence"@en ; rdfs:range ; rdfs:subPropertyOf obo:RO_0002314 . obo:NCBITaxon_267390 a rdfs:Class ; rdfs:label "SARS coronavirus SinP1" ; rdfs:subClassOf obo:NCBITaxon_694009 . obo:HP_0031673 a rdfs:Class ; rdfs:label "Orthodromic atrioventricular reentrant tachycardia" ; rdfs:comment "A type of atrioventricular reentrant tachycardia (AVRT) where the atrioventricular node is used for anterograde conduction and the accessory pathway for retrograde conduction." ; rdfs:subClassOf obo:HP_0011717 . obo:CIDO_0020317 a rdfs:Class ; rdfs:label "UTHSC/UCH SARS-CoV-2-RT-PCR Assay" ; rdfs:seeAlso ; rdfs:subClassOf obo:CIDO_0000454 . obo:PR_Q8N3C7 a rdfs:Class ; rdfs:label "CAP-Gly domain-containing linker protein 4 (human)" ; rdfs:comment "A CAP-Gly domain-containing linker protein 4 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000029067 , obo:PR_000031063 . obo:CHEBI_36688 a rdfs:Class ; rdfs:label "heterotricyclic compound" ; rdfs:subClassOf obo:CHEBI_33671 . obo:VO_0005096 a rdfs:Class ; rdfs:label "S-268019"@en ; rdfs:subClassOf obo:VO_0005202 . obo:VO_0005200 a rdfs:Class ; rdfs:label "COVID-19 recombinant adenoviral vector vaccine"@en ; rdfs:subClassOf obo:VO_0005199 . obo:PR_000001427 a rdfs:Class ; rdfs:label "LPAR1/S1PR1-like lysophospholipid receptor" ; rdfs:comment "A rhodopsin-like G-protein coupled receptor that is a translation product of the human LPAR1 to LPAR6 or S1PR1 to S1PR5 genes, 1:1 orthologs thereof, or a semi-ortholog thereof. The active form binds lysophosphatidic acid or sphingosine 1-phosphate." ; rdfs:subClassOf obo:PR_000001094 . obo:NCBITaxon_681850 a rdfs:Class ; rdfs:label "Kenya bat coronavirus BtKY03" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:CHEBI_60895 a rdfs:Class ; rdfs:label "D-alpha-amino acid anion" ; rdfs:comment "Any alpha-amino acid anion in which the parent amino acid has D-configuration." ; rdfs:subClassOf obo:CHEBI_33558 . obo:CHEBI_53468 a rdfs:Class ; rdfs:label "salicylanilides" ; rdfs:comment "The compound salicylanilide and its derivatives." ; rdfs:subClassOf obo:CHEBI_13248 , obo:CHEBI_32114 . obo:DOID_2055 a rdfs:Class ; rdfs:label "post-traumatic stress disorder" ; rdfs:comment "An anxiety disorder which results from a traumatic experience that results in psychological trauma." ; rdfs:subClassOf obo:DOID_2030 . obo:GO_0046483 a rdfs:Class ; rdfs:label "heterocycle metabolic process" ; rdfs:comment "The chemical reactions and pathways involving heterocyclic compounds, those with a cyclic molecular structure and at least two different atoms in the ring (or rings)." ; rdfs:subClassOf obo:GO_0044237 . obo:CIDO_0020106 a rdfs:Class ; rdfs:label "CSI SARS-CoV-2 RT PCR Test" ; rdfs:seeAlso ; rdfs:subClassOf obo:CIDO_0000454 . obo:NCBITaxon_591068 a rdfs:Class ; rdfs:label "Murine coronavirus MHV-JHM.IA" ; rdfs:subClassOf obo:NCBITaxon_11138 . a rdfs:Class ; rdfs:label "Azabicyclo Compounds [Chemical/Ingredient]" ; rdfs:subClassOf , . obo:PR_P50135 a rdfs:Class ; rdfs:label "histamine N-methyltransferase (human)" ; rdfs:comment "A histamine N-methyltransferase that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000008656 , obo:PR_000029067 . obo:CHEBI_60798 a rdfs:Class ; rdfs:label "excitatory amino acid antagonist" ; rdfs:comment "Any substance which inhibits the action of receptors for excitatory amino acids." ; rdfs:subClassOf obo:CHEBI_48706 . obo:PR_000007204 a rdfs:Class ; rdfs:label "estrogen receptor" ; rdfs:comment "A protein that is a translation product of the human ESR1 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:DRON_00000009 a rdfs:Class ; rdfs:label "portion of colloid"@en ; rdfs:comment "a portion of mixture whereby the grains of at least one object aggregate are >10-9m and <1 μm in size (the dispersed material) and the grains of at least one other object aggregate are <10-9m in size (continuous medium)"@en ; rdfs:subClassOf obo:DRON_00000006 . a rdfs:Class ; rdfs:label "Haemophilus Infections [Disease/Finding]" ; rdfs:subClassOf . obo:GO_0032270 a rdfs:Class ; rdfs:label "positive regulation of cellular protein metabolic process" ; rdfs:comment "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving a protein, occurring at the level of an individual cell." ; rdfs:subClassOf obo:GO_0031325 , obo:GO_0032268 , obo:GO_0051247 . obo:CIDO_0000478 a rdfs:Class ; rdfs:label "CAQYYNGIMVLPGVA duplic" ; rdfs:comment "A coronavirus epitope that is part of some S protein from HCoV NL63 composed of the following amino acids CAQYYNGIMVLPGVA" ; rdfs:subClassOf obo:CIDO_0000449 . obo:GO_0035726 a rdfs:Class ; rdfs:label "common myeloid progenitor cell proliferation" ; rdfs:comment "The multiplication or reproduction of common myeloid progenitor cells, resulting in the expansion of a cell population. A common myeloid progenitor cell is a progenitor cell committed to the myeloid lineage." ; rdfs:subClassOf obo:GO_0008283 . obo:PR_000012477 a rdfs:Class ; rdfs:label "cGMP-specific 3',5'-cyclic phosphodiesterase" ; rdfs:comment "A GAF-containing cyclic nucleotide-dependent 3',5'-cyclic phosphodiesterase that is a translation product of the human PDE5A gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000050164 . obo:GO_0048661 a rdfs:Class ; rdfs:label "positive regulation of smooth muscle cell proliferation" ; rdfs:comment "Any process that activates or increases the rate or extent of smooth muscle cell proliferation." ; rdfs:subClassOf obo:GO_0008284 , obo:GO_0042127 . obo:GO_0032870 a rdfs:Class ; rdfs:label "cellular response to hormone stimulus" ; rdfs:comment "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hormone stimulus." ; rdfs:subClassOf obo:GO_0009725 , obo:GO_0071310 , obo:GO_0071495 . obo:CHEBI_77307 a rdfs:Class ; rdfs:label "cardioprotective agent" ; rdfs:comment "Any protective agent that is able to prevent damage to the heart." ; rdfs:subClassOf obo:CHEBI_50267 . a rdfs:Class ; rdfs:label "Liver Diseases [Disease/Finding]" ; rdfs:subClassOf . obo:PR_P0DTC1-1 a rdfs:Class ; rdfs:label "replicase polyprotein 1a (SARS-CoV-2)" ; rdfs:comment "A rep gene translation product (SARS-CoV-2) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P0DTC1-1." ; rdfs:subClassOf obo:PR_000050263 . obo:VO_0005190 a rdfs:Class ; rdfs:label "IMP CoVac-1"@en ; rdfs:comment "A SARS-CoV-2 subunit vaccine developed by University Hospital Tuebingen" ; rdfs:subClassOf obo:VO_0005202 . obo:CIDO_0000755 a rdfs:Class ; rdfs:label "SARS-CoV2 M protein binding to human ETFA" ; rdfs:comment "SARS-CoV2 M protein binding to human ETFA, as evidented by an affinity-purification mass spectrometry experiment" ; rdfs:subClassOf obo:CIDO_0000055 . obo:NCBITaxon_11143 a rdfs:Class ; rdfs:label "Murine hepatitis virus strain defective JHM" ; rdfs:subClassOf obo:NCBITaxon_11138 . obo:CHEBI_59814 a rdfs:Class ; rdfs:label "L-alpha-amino acid anion" ; rdfs:comment "Conjugate base of an L-alpha-amino acid arising from deprotonation of the C-1 carboxy group." ; rdfs:subClassOf obo:CHEBI_33558 . a rdfs:Class ; rdfs:label "Candidiasis, Vulvovaginal [Disease/Finding]" ; rdfs:subClassOf , . obo:PR_Q96IV0 a rdfs:Class ; rdfs:label "peptide-N(4)-(N-acetyl-beta-glucosaminyl)asparagine amidase (human)" ; rdfs:comment "A peptide-N(4)-(N-acetyl-beta-glucosaminyl)asparagine amidase that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000011196 , obo:PR_000029067 . obo:CIDO_0020246 a rdfs:Class ; rdfs:label "Q-Plex SARS-CoV-2 Human IgG (4 Plex)" ; rdfs:seeAlso ; rdfs:subClassOf obo:CIDO_0000454 . obo:CHEBI_35735 a rdfs:Class ; rdfs:label "dicarboxylic acid monoamide" ; rdfs:subClassOf obo:CHEBI_23690 . obo:DRON_00019163 a rdfs:Class ; rdfs:label "eltrombopag" ; rdfs:subClassOf obo:OBI_0000047 . obo:CIDO_0000127 a rdf:Property ; rdfs:label "drug has protein target as agonist"@en ; rdfs:comment "An object property that represents a relation between a drug and a protein where the drug can target the protein as an receptor agonist. An agonist is a drug that binds to a receptor and activates the receptor to produce a biological response." ; rdfs:range ; rdfs:subPropertyOf obo:CIDO_0000124 . obo:PR_000001376 a rdfs:Class ; rdfs:label "interleukin-18" ; rdfs:comment "A protein that is a translation product of the human IL18 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:PR_000006030 a rdfs:Class ; rdfs:label "procathepsin L" ; rdfs:comment "A cathepsin-like protease that is a translation product of the human CTSL gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000040662 . obo:CIDO_0020038 a rdfs:Class ; rdfs:label "Avera Institute for Human Genetics SARS-CoV-2 Assay" ; rdfs:seeAlso ; rdfs:subClassOf obo:CIDO_0000454 . obo:OPMI_0000563 a rdfs:Class ; rdfs:label "device exposure start datetime"@en ; rdfs:comment "The date and time on which a device exposure starts." ; rdfs:subClassOf obo:OPMI_0000556 . obo:PR_000004102 a rdfs:Class ; rdfs:label "AP-2 complex subunit mu" ; rdfs:comment "A protein that is a translation product of the human AP2M1 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . a rdfs:Class ; rdfs:label "Endocrine System Diseases [Disease/Finding]" ; rdfs:subClassOf . a rdfs:Class ; rdfs:label "Benzopyrans [Chemical/Ingredient]" ; rdfs:subClassOf , . a rdfs:Class ; rdfs:label "Mycobacterium Infections [Disease/Finding]" ; rdfs:subClassOf . a rdfs:Class ; rdfs:label "Reye Syndrome [Disease/Finding]" ; rdfs:subClassOf , . obo:NCBITaxon_1746084 a rdfs:Class ; rdfs:label "Bat coronavirus M.nat/GER/3856/2014" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:NCBITaxon_249066 a rdfs:Class ; rdfs:label "SARS coronavirus HGZ8L1-A" ; rdfs:subClassOf obo:NCBITaxon_694009 . obo:CHEBI_78115 a rdfs:Class ; rdfs:label "fatty acid anion 4:0" ; rdfs:comment "Any saturated fatty acid anion containing 4 carbons. Formed by deprotonation of the carboxylic acid moiety. Major species at pH 7.3." ; rdfs:subClassOf obo:CHEBI_58951 , obo:CHEBI_58953 . a rdfs:Class ; rdfs:label "Tetanus [Disease/Finding]" ; rdfs:subClassOf . a rdfs:Class ; rdfs:label "Nephritis [Disease/Finding]" ; rdfs:subClassOf . obo:CHEBI_64018 a rdfs:Class ; rdfs:label "protein kinase C agonist" ; rdfs:comment "An agonist that selectively binds to and activates a protein kinase C receptor" ; rdfs:subClassOf obo:CHEBI_64106 . obo:HP_0011029 a rdfs:Class ; rdfs:label "Internal hemorrhage" ; rdfs:comment "The presence of hemorrhage within the body." ; rdfs:subClassOf obo:HP_0001871 , obo:HP_0011025 . obo:OBI_0000832 a rdfs:Class ; rdfs:label "measurement device" ; rdfs:comment "A device in which a measure function inheres." ; rdfs:subClassOf obo:OBI_0000968 . obo:CHEBI_23981 a rdfs:Class ; rdfs:label "ethanolamines" ; rdfs:subClassOf obo:CHEBI_22478 . obo:GO_0032355 a rdfs:Class ; rdfs:label "response to estradiol" ; rdfs:comment "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of stimulus by estradiol, a C18 steroid hormone hydroxylated at C3 and C17 that acts as a potent estrogen." ; rdfs:subClassOf obo:GO_0014070 , obo:GO_0033993 , obo:GO_1901700 . a rdfs:Class ; rdfs:label "Simvastatin [Chemical/Ingredient]" ; rdfs:subClassOf . obo:CHEBI_5653 a rdfs:Class ; rdfs:label "hemiacetal" ; rdfs:comment "A compound having the general formula RR'C(OH)OR'' (R'' =/= H)." ; rdfs:subClassOf obo:CHEBI_30879 . obo:PR_000006992 a rdfs:Class ; rdfs:label "eukaryotic translation initiation factor 4E type 2" ; rdfs:comment "A protein that is a translation product of the human EIF4E2 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:VO_0005341 a rdfs:Class ; rdfs:label "VB10.2210"@en ; rdfs:comment "A SARS-CoV-2 T-Cell-based DNA vaccine developed by Vaccibody AS" ; rdfs:subClassOf obo:VO_0005203 . obo:CIDO_0000556 a rdfs:Class ; rdfs:label "TPFMILLVALSLCLT" ; rdfs:comment "A coronavirus epitope that is part of some S protein from HCoV 229E composed of the following amino acids TPFMILLVALSLCLT" ; rdfs:subClassOf obo:CIDO_0000451 . obo:OBI_0000880 a rdfs:Class ; rdfs:label "RNA extract" ; rdfs:comment "an extract which is the output of an extraction process in which RNA molecules are isolated from a specimen." ; rdfs:subClassOf obo:OBI_0001010 . obo:PR_P08235 a rdfs:Class ; rdfs:label "mineralocorticoid receptor (human)" ; rdfs:comment "A mineralocorticoid receptor that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000011407 , obo:PR_000029067 . obo:CHEBI_35693 a rdfs:Class ; rdfs:label "dicarboxylic acid anion" ; rdfs:subClassOf obo:CHEBI_29067 . obo:VO_0000136 a rdfs:Class ; rdfs:label "adenovirus vaccine vector" ; rdfs:comment "a viral vaccine vector that uses an adenovirus as the vector." ; rdfs:subClassOf obo:VO_0000610 . obo:PR_Q9NZL9 a rdfs:Class ; rdfs:label "methionine adenosyltransferase 2 subunit beta (human)" ; rdfs:comment "A methionine adenosyltransferase 2 subunit beta that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000010203 , obo:PR_000029067 . obo:PR_P35372 a rdfs:Class ; rdfs:label "mu-type opioid receptor (human)" ; rdfs:comment "A mu-type opioid receptor that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000001612 , obo:PR_000029067 . obo:CHEBI_68452 a rdfs:Class ; rdfs:label "azole" ; rdfs:comment "Any monocyclic heteroarene consisting of a five-membered ring containing nitrogen. Azoles can also contain one or more other non-carbon atoms, such as nitrogen, sulfur or oxygen." ; rdfs:subClassOf obo:CHEBI_38101 , obo:CHEBI_38179 . obo:NCBITaxon_1159906 a rdfs:Class ; rdfs:label "Sparrow coronavirus HKU17" ; rdfs:subClassOf obo:NCBITaxon_2724161 . obo:NCBITaxon_903619 a rdfs:Class ; rdfs:label "Kenya bat coronavirus BtKY81" ; rdfs:subClassOf obo:NCBITaxon_2664420 . a rdfs:Class ; rdfs:label "Sexually Transmitted Diseases, Bacterial [Disease/Finding]" ; rdfs:subClassOf , . obo:NCBITaxon_1532170 a rdfs:Class ; rdfs:label "Alphacoronavirus BtCoV/GrNC7/Neo_cap/RSA/2012" ; rdfs:subClassOf obo:NCBITaxon_366617 . obo:OBI_0002516 a rdfs:Class ; rdfs:label "brain specimen" ; rdfs:comment "A specimen that is derived from brain." ; rdfs:subClassOf obo:OBI_0001479 . obo:CIDO_0000614 a rdfs:Class ; rdfs:label "SARS-CoV-2 protein amino acid deletion"@en ; rdfs:comment "A variation that results in a deletion of an amino acid of SARS-CoV-2 protein in comparison to the reference sequence." ; rdfs:subClassOf obo:VariO_0014 . obo:PR_000006147 a rdfs:Class ; rdfs:label "lanosterol 14-alpha demethylase" ; rdfs:comment "A protein that is a translation product of the human CYP51A1 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:CIDO_0020314 a rdfs:Class ; rdfs:label "UDX SARS-CoV-2 Molecular Assay" ; rdfs:seeAlso ; rdfs:subClassOf obo:CIDO_0000454 . obo:GO_0010243 a rdfs:Class ; rdfs:label "response to organonitrogen compound" ; rdfs:comment "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an organonitrogen stimulus. An organonitrogen compound is formally a compound containing at least one carbon-nitrogen bond." ; rdfs:subClassOf obo:GO_0010033 , obo:GO_1901698 . obo:PR_P20309 a rdfs:Class ; rdfs:label "muscarinic acetylcholine receptor M3 (human)" ; rdfs:comment "A muscarinic acetylcholine receptor M3 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000001615 , obo:PR_000029067 . obo:CHEBI_50047 a rdfs:Class ; rdfs:label "organic amino compound" ; rdfs:comment "A compound formally derived from ammonia by replacing one, two or three hydrogen atoms by organyl groups." ; rdfs:subClassOf obo:CHEBI_35352 , obo:CHEBI_50860 . obo:PR_000013586 a rdfs:Class ; rdfs:label "Ras-related protein Rab-14" ; rdfs:comment "A protein that is a translation product of the human RAB14 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:CIDO_0000733 a rdfs:Class ; rdfs:label "SARS-CoV2 E protein binding to human SLC44A2" ; rdfs:comment "SARS-CoV2 E protein binding to human SLC44A2, as evidented by an affinity-purification mass spectrometry experiment" ; rdfs:subClassOf obo:CIDO_0000046 . obo:GO_0060193 a rdfs:Class ; rdfs:label "positive regulation of lipase activity" ; rdfs:comment "Any process that increases the frequency, rate or extent of lipase activity, the hydrolysis of a lipid or phospholipid." ; rdfs:subClassOf obo:GO_0051345 , obo:GO_0060191 . obo:NCBITaxon_694000 a rdfs:Class ; rdfs:label "Miniopterus bat coronavirus 1" ; rdfs:subClassOf obo:NCBITaxon_2509497 . obo:OBI_0002607 a rdfs:Class ; rdfs:label "oral swab specimen" ; rdfs:comment "A specimen that is collected with a swab from the inside surface of a mouth." ; rdfs:subClassOf obo:OBI_0002599 . obo:PR_Q8IW41 a rdfs:Class ; rdfs:label "MAP kinase-activated protein kinase 5 (human)" ; rdfs:comment "A MAP kinase-activated protein kinase 5 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000010167 , obo:PR_000029067 . obo:OBI_0001933 a rdfs:Class ; rdfs:label "value specification" ; rdfs:comment "An information content entity that specifies a value within a classification scheme or on a quantitative scale." ; rdfs:subClassOf obo:IAO_0000030 . obo:IDO_0000597 a rdfs:Class ; rdfs:label "host exposure to environment containing infectious agent"@en ; rdfs:comment "A process in which a potential host of an infectious agent is exposed to an environment in which the infectious agent is present and physical contact between the two can occur, but such contact is not planned."@en ; rdfs:subClassOf obo:IDO_0000658 . obo:PR_O95391 a rdfs:Class ; rdfs:label "pre-mRNA-splicing factor SLU7 (human)" ; rdfs:comment "A pre-mRNA-splicing factor SLU7 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000015250 , obo:PR_000029067 . obo:OBI_2000006 a rdfs:Class ; rdfs:label "upper respiratory tract specimen" ; rdfs:comment "A specimen that is derived from some upper respiratory tract " ; rdfs:subClassOf obo:OBI_0001479 . obo:CHEBI_17126 a rdfs:Class ; rdfs:label "carnitine" ; rdfs:comment "An amino-acid betaine that is butanoate substituted with a hydroxy group at position C-3 and a trimethylammonium group at C-4." ; rdfs:subClassOf obo:CHEBI_22860 . obo:NCBITaxon_903608 a rdfs:Class ; rdfs:label "Kenya bat coronavirus BtKY70" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:CHEBI_37930 a rdfs:Class ; rdfs:label "phenothiazine antipsychotic drug" ; rdfs:subClassOf obo:CHEBI_65190 . obo:NCBITaxon_229032 a rdfs:Class ; rdfs:label "Porcine epidemic diarrhea virus CV777" ; rdfs:subClassOf obo:NCBITaxon_28295 . obo:NCBITaxon_627435 a rdfs:Class ; rdfs:label "Feline coronavirus UU8" ; rdfs:subClassOf obo:NCBITaxon_12663 . obo:CHEBI_25675 a rdfs:Class ; rdfs:label "oligomycin" ; rdfs:comment "Any of the 26-membered ring macrolides produced by Streptomyces species that can be toxic to other organisms through their ability to inhibit mitochondrial membrane-bound ATP synthases." ; rdfs:subClassOf obo:CHEBI_25105 , obo:CHEBI_25106 , obo:CHEBI_72600 . obo:CIDO_0000141 a rdf:Property ; rdfs:label "chemical effective in vitro against virus"@en ; rdfs:comment "An object property that represents a relation between a chemical entity and a virus where the chemical has an effective role against viral infection in vitro" ; rdfs:range ; rdfs:subPropertyOf obo:CIDO_0000139 . obo:DOID_0080642 a rdfs:Class ; rdfs:label "Middle East respiratory syndrome"@en ; rdfs:comment "A Coronavirus infection that is characterized by severe respiratory illness, including fever, cough, and shortness of breath and that has_material_basis_in MERS-CoV." ; rdfs:subClassOf obo:DOID_0080599 . a rdfs:Class ; rdfs:label "Hydrocarbons, Aromatic [Chemical/Ingredient]" ; rdfs:subClassOf . obo:CIDO_0020261 a rdfs:Class ; rdfs:label "Real-Q 2019-nCoV Detection Kit" ; rdfs:seeAlso ; rdfs:subClassOf obo:CIDO_0000454 . obo:CIDO_0000506 a rdfs:Class ; rdfs:label "GLNASVTLKICKFSR" ; rdfs:comment "A coronavirus epitope that is part of some S protein from HCoV NL63 composed of the following amino acids GLNASVTLKICKFSR" ; rdfs:subClassOf obo:CIDO_0000449 . obo:CHEBI_26375 a rdfs:Class ; rdfs:label "pterins" ; rdfs:subClassOf obo:CHEBI_26373 . a rdfs:Class ; rdfs:label "Organic Chemicals [Chemical/Ingredient]" ; rdfs:subClassOf . obo:CIDO_0020331 a rdfs:Class ; rdfs:label "WANTAI SARS-CoV-2 Ab ELISA" ; rdfs:seeAlso ; rdfs:subClassOf obo:CIDO_0000454 . obo:VO_0000624 a rdfs:Class ; rdfs:label "subunit vaccine role"@en ; rdfs:comment "a vaccine role that indicates the vaccine being a subunit vaccine. " ; rdfs:subClassOf obo:VO_0000615 . obo:CHEBI_35247 a rdfs:Class ; rdfs:label "D-serine zwitterion" ; rdfs:comment "A serine zwitterion obtained by transfer of a proton from the carboxy to the amino group of D-serine." ; rdfs:subClassOf obo:CHEBI_35243 . obo:ENVO_01000814 a rdfs:Class ; rdfs:label "solid environmental material"@en ; rdfs:comment "An environmental material which is in a solid state." ; rdfs:subClassOf obo:ENVO_00010483 . obo:RO_0000086 a rdf:Property ; rdfs:label "has quality"@en ; rdfs:comment "a relation between an independent continuant (the bearer) and a quality, in which the quality specifically depends on the bearer for its existence"@en ; rdfs:range obo:BFO_0000019 ; rdfs:subPropertyOf obo:RO_0000053 . obo:CHEBI_66484 a rdfs:Class ; rdfs:label "silvestrol" ; rdfs:comment "An organic heterotricyclic compound that consists of a 2,3,3a,8b-tetrahydro-H-benzo[b]cyclopenta[d]furan framework substituted by hydroxy groups at positions C-1 and C-8b, a methoxycarbonyl group at C-2, a phenyl group at C-3, a 4-methoxyphenyl group at C-3a, a methoxy group at C-8 and a 1,4-dioxan-2-yloxy group at position C-6 which in turn is substituted by a methoxy group at position 3 and a 1,2-dihydroxyethyl group at position 6. Isolated from Aglaia silvestris, it exhibits antineoplastic activity." ; rdfs:subClassOf obo:CHEBI_25248 , obo:CHEBI_25698 , obo:CHEBI_26979 , obo:CHEBI_46926 . obo:PR_O94768 a rdfs:Class ; rdfs:label "serine/threonine-protein kinase 17B (human)" ; rdfs:comment "A serine/threonine-protein kinase 17B that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000015744 , obo:PR_000029067 . obo:CIDO_0001206 a rdfs:Class ; rdfs:label "Multiple Real-Time PCR Kit for Detection of 2019-nCoV. (Jiangsu Bioperfectus Technologies Co., Ltd.)" ; rdfs:comment "Poduct storage conditions and expiration date: Store away from light at -20±5℃, valid for 8 months" ; rdfs:subClassOf obo:CIDO_0000021 . obo:GO_0071417 a rdfs:Class ; rdfs:label "cellular response to organonitrogen compound" ; rdfs:comment "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an organonitrogen stimulus. An organonitrogen compound is formally a compound containing at least one carbon-nitrogen bond." ; rdfs:subClassOf obo:GO_0010243 , obo:GO_0071310 , obo:GO_0071495 , obo:GO_1901699 . obo:PR_000004061 a rdfs:Class ; rdfs:label "anoctamin-6" ; rdfs:comment "A protein that is a translation product of the human ANO6 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:DRON_00000034 a rdfs:Class ; rdfs:label "anti-hypertensive function of a drug product" ; rdfs:comment "a therapeutic function of a drug product that is realized by administration of the drug product resulting in a decrease of systemic arterial pressure"@en ; rdfs:subClassOf obo:DRON_00000032 . obo:CHEBI_84087 a rdfs:Class ; rdfs:label "human urinary metabolite" ; rdfs:comment "Any metabolite (endogenous or exogenous) found in human urine samples." ; rdfs:subClassOf obo:CHEBI_77746 . obo:HP_0002795 a rdfs:Class ; rdfs:label "Abnormal respiratory system physiology" ; rdfs:subClassOf obo:HP_0002086 . obo:GO_1902533 a rdfs:Class ; rdfs:label "positive regulation of intracellular signal transduction" ; rdfs:comment "Any process that activates or increases the frequency, rate or extent of intracellular signal transduction." ; rdfs:subClassOf obo:GO_0009967 , obo:GO_1902531 . obo:NCBITaxon_1346308 a rdfs:Class ; rdfs:label "Betacoronavirus BtCoV/Rhi_hip/R13-08/SPA/2010" ; rdfs:subClassOf obo:NCBITaxon_696098 . obo:NCBITaxon_7711 a rdfs:Class ; rdfs:label "Chordata" ; rdfs:subClassOf obo:NCBITaxon_33511 . obo:CHEBI_35753 a rdfs:Class ; rdfs:label "tricarboxylic acid anion" ; rdfs:comment "Any anion of a tricarboxylic acid formed by deprotonation of at least one carboxy group." ; rdfs:subClassOf obo:CHEBI_29067 . obo:NCBITaxon_681865 a rdfs:Class ; rdfs:label "Kenya bat coronavirus BtKY19" ; rdfs:subClassOf obo:NCBITaxon_2664420 . a rdfs:Class ; rdfs:label "DNA Virus Infections [Disease/Finding]" ; rdfs:subClassOf obo:DOID_934 . obo:NCBITaxon_1511625 a rdfs:Class ; rdfs:label "Coronavirus BtCoV/M9/HUN/2013" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:CHEBI_50266 a rdfs:Class ; rdfs:label "prodrug" ; rdfs:comment "A compound that, on administration, must undergo chemical conversion by metabolic processes before becoming the pharmacologically active drug for which it is a prodrug." ; rdfs:subClassOf obo:CHEBI_136859 , obo:CHEBI_23888 . a rdfs:Class ; rdfs:label "Uncouplers [MoA]" ; rdfs:subClassOf . obo:CHEBI_33662 a rdfs:Class ; rdfs:label "annulene" ; rdfs:comment "A mancude monocyclic hydrocarbon without side chains of the general formula CnHn (n is an even number) or CnHn+1 (n is an odd number). In systematic nomenclature an annulene with seven or more carbon atoms may be named [n]annulene, where n is the number of carbon atoms." ; rdfs:subClassOf obo:CHEBI_33664 . obo:CIDO_0000586 a rdfs:Class ; rdfs:label "SARS-CoV-2 orf6 protein interaction with host protein"@en ; rdfs:comment "A molecular interaction that has participant of the SARS-CoV-2 orf6 protein and a host protein" ; rdfs:subClassOf obo:CIDO_0000348 . obo:VO_0000580 a rdfs:Class ; rdfs:label "vaccine adjuvant" ; rdfs:comment "a vaccine component that is chemical substance added to vaccine and enhance and direct immune response to protective antigen. Many of vaccine adjuvants cause a range of serious side-effects." ; rdfs:subClassOf obo:VO_0000179 . obo:CIDO_0000937 a rdfs:Class ; rdfs:label "SARS-CoV2 nsp8 protein binding to human MRPS27" ; rdfs:comment "SARS-CoV2 nsp8 protein binding to human MRPS27, as evidented by an affinity-purification mass spectrometry experiment" ; rdfs:subClassOf obo:CIDO_0000582 . obo:NCBITaxon_864600 a rdfs:Class ; rdfs:label "Bat coronavirus BM48-39/BGR/2008" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:NCBITaxon_622714 a rdfs:Class ; rdfs:label "Bat coronavirus Hipposideros/GhanaKwam/24/2008" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:NCBITaxon_1076419 a rdfs:Class ; rdfs:label "Alphacoronavirus N.las/E/Spain/2007" ; rdfs:subClassOf obo:NCBITaxon_366617 . obo:VO_0005175 a rdfs:Class ; rdfs:label "ChulaCov19"@en ; rdfs:comment "A SARS-CoV-2 mRNA vaccine manufactured by Chulalongkorn University" ; rdfs:subClassOf obo:VO_0005198 . obo:NCBITaxon_9913 a rdfs:Class ; rdfs:label "Bos taurus" ; rdfs:subClassOf obo:NCBITaxon_9903 . obo:GO_0055074 a rdfs:Class ; rdfs:label "calcium ion homeostasis" ; rdfs:comment "Any process involved in the maintenance of an internal steady state of calcium ions within an organism or cell." ; rdfs:subClassOf obo:GO_0055065 , obo:GO_0072507 . obo:CIDO_0000710 a rdfs:Class ; rdfs:label "T2007I in SARS-CoV-2 pp1a protein"@en ; rdfs:comment "An AA mutation or AA variant that has mutated an amino acid at position 2007 into isoleucine" ; rdfs:subClassOf obo:CIDO_0001074 . obo:OPMI_0000530 a rdfs:Class ; rdfs:label "condition end datetime"@en ; rdfs:comment "The date and time on which a clinical condition ends." ; rdfs:subClassOf obo:OPMI_0000528 . a rdfs:Class ; rdfs:label "Astemizole [Chemical/Ingredient]" ; rdfs:subClassOf . obo:UBERON_0003103 a rdfs:Class ; rdfs:label "compound organ" ; rdfs:comment "Anatomical structure that has as its parts two or more multi-tissue structures of at least two different types and which through specific morphogenetic processes forms a single distinct structural unit demarcated by bona fide boundaries from other distinct anatomical structures of different types." ; rdfs:subClassOf obo:UBERON_0000062 . obo:RO_0002497 a rdf:Property ; rdfs:label "existence ends during or before" ; rdfs:range . obo:CHEBI_48561 a rdfs:Class ; rdfs:label "dopaminergic antagonist" ; rdfs:comment "A drug that binds to but does not activate dopamine receptors, thereby blocking the actions of dopamine or exogenous agonists." ; rdfs:subClassOf obo:CHEBI_48560 . obo:PR_000001590 a rdfs:Class ; rdfs:label "kappa-type opioid receptor" ; rdfs:comment "An opioid receptor protein that is a translation product of the human OPRK1 gene or a 1:1 ortholog thereof. The preferred ligand is dynorphin." ; rdfs:subClassOf obo:PR_000001497 . obo:CHEBI_33543 a rdfs:Class ; rdfs:label "sulfonate" ; rdfs:comment "The sulfur oxoanion formed by deprotonation of sulfonic acid." ; rdfs:subClassOf obo:CHEBI_33482 . obo:GO_0043933 a rdfs:Class ; rdfs:label "protein-containing complex organization" ; rdfs:comment "Any process in which macromolecules aggregate, disaggregate, or are modified, resulting in the formation, disassembly, or alteration of a protein complex." ; rdfs:subClassOf obo:GO_0016043 . obo:PR_000060044 a rdfs:Class ; rdfs:label "mitochondrial import inner membrane translocase subunit Tim29" ; rdfs:comment "A protein that is a translation product of the human TIMM29 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:PR_000007543 a rdfs:Class ; rdfs:label "peptidyl-prolyl cis-trans isomerase FKBP7" ; rdfs:comment "A protein that is a translation product of the human FKBP7 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . a rdfs:Class ; rdfs:label "Vulvitis [Disease/Finding]" ; rdfs:subClassOf . obo:GO_0019083 a rdfs:Class ; rdfs:label "viral transcription" ; rdfs:comment "The process by which a viral genome, or part of a viral genome, is transcribed within the host cell." ; rdfs:subClassOf obo:GO_0016032 . obo:VO_0005135 a rdfs:Class ; rdfs:label "ChAdOx1-MERS-S vaccine" ; rdfs:comment "A MERS recombinant vector made of Chimpanzee adenovirus Oxford 1 vector expressing S protein from MERS-CoV’" ; rdfs:subClassOf obo:VO_0004900 . obo:NCBITaxon_1699331 a rdfs:Class ; rdfs:label "Myotis Bat Alphacoronavirus strain YNXY_21C" ; rdfs:subClassOf obo:NCBITaxon_366617 . obo:CHEBI_32877 a rdfs:Class ; rdfs:label "primary amine" ; rdfs:comment "A compound formally derived from ammonia by replacing one hydrogen atom by a hydrocarbyl group." ; rdfs:subClassOf obo:CHEBI_32952 , obo:CHEBI_50994 . obo:CHEBI_76817 a rdfs:Class ; rdfs:label "EC 2.7.10.* (protein-tyrosine kinase) inhibitor" ; rdfs:comment "An EC 2.7.* (P-containing group transferase) inhibitor that interferes with the action of any protein-tyrosine kinase (EC 2.7.10.*)." ; rdfs:subClassOf obo:CHEBI_37699 , obo:CHEBI_76668 . obo:NCBITaxon_1346312 a rdfs:Class ; rdfs:label "Betacoronavirus BtCoV/Rhi_hip/R8-09/SPA/2010" ; rdfs:subClassOf obo:NCBITaxon_696098 . obo:CHEBI_47499 a rdfs:Class ; rdfs:label "imipramine" ; rdfs:comment "A dibenzoazepine that is 5H-dibenzo[b,f]azepine substituted by a 3-(dimethylamino)propyl group at the nitrogen atom." ; rdfs:subClassOf obo:CHEBI_47804 . obo:NCBITaxon_931901 a rdfs:Class ; rdfs:label "Alphacoronavirus Eptesicus fuscus/Appalachian Ridge/P1-C414//IT/USA/2009" ; rdfs:subClassOf obo:NCBITaxon_366617 . obo:CIDO_0000629 a rdfs:Class ; rdfs:label "P80R in SARS-CoV-2 N protein" ; rdfs:comment "An AA variant that has mutated an amino acid at position 800 into a arginine in N protein." ; rdfs:subClassOf obo:CIDO_0000596 . obo:CIDO_0000980 a rdfs:Class ; rdfs:label "SARS-CoV2 orf3b protein binding to human STOML2" ; rdfs:comment "SARS-CoV2 orf3b protein binding to human STOML2, as evidented by an affinity-purification mass spectrometry experiment" ; rdfs:subClassOf obo:CIDO_0000585 . obo:OAE_0000381 a rdfs:Class ; rdfs:label "abnormal blood pressure AE" ; rdfs:comment "a cardiovascular disorder AE that has an outcome of abnormal blood pressure, representing altered tension of the blood within the systemic arteries" ; rdfs:subClassOf obo:OAE_0000493 . obo:CIDO_0020254 a rdfs:Class ; rdfs:label "Quest Diagnostics RC SARS-CoV-2 Assay" ; rdfs:seeAlso ; rdfs:subClassOf obo:CIDO_0000454 . obo:CHEBI_77023 a rdfs:Class ; rdfs:label "EC 2.3.3.1 [citrate (Si)-synthase] inhibitor" ; rdfs:comment "An EC 2.3.3.* (acyltransferase converting acyl to alkyl group on transfer) inhibitor that interferes with the action of citrate (Si)-synthase, EC 2.3.3.1." ; rdfs:subClassOf obo:CHEBI_77022 . obo:CIDO_0000422 a rdfs:Class ; rdfs:label "human COVID-19 patient"@en ; rdfs:comment "Hong Yu, Oliver He" ; rdfs:subClassOf obo:CIDO_0000419 . obo:OPMI_0000481 a rdf:Property ; rdfs:label "has identifier"@en ; rdfs:range . obo:PR_P37198 a rdfs:Class ; rdfs:label "nuclear pore glycoprotein p62 (human)" ; rdfs:comment "A nuclear pore glycoprotein p62 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000011521 , obo:PR_000029067 . obo:PR_000010415 a rdfs:Class ; rdfs:label "misshapen-like kinase 1" ; rdfs:comment "A protein that is a translation product of the human MINK1 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:PR_000001810 a rdfs:Class ; rdfs:label "CSF-1/PDGF receptor-type tyrosine-protein kinase" ; rdfs:comment "A protein with core architecture consisting of asignal sequence, 5 Ig-like domains, followed by a transmembrane sequence, followed by a Protein tyrosine kinase domain (Pfam:PF07714). However, only 1-3 of the Ig domains are detected by the Pfam HMMs in most of the sequences. Pfam:PF00047 is most common, but other members of the Ig domain clan, Pfam:PF07679 and Pfam:PF07686 can be identified instead. The fourth Ig domain lacks the disulfide-bonded cysteines." ; rdfs:subClassOf obo:PR_000000001 . obo:CIDO_0000986 a rdfs:Class ; rdfs:label "SARS-CoV2 orf8 protein binding to human ADAM9" ; rdfs:comment "SARS-CoV2 orf8 protein binding to human ADAM9, as evidented by an affinity-purification mass spectrometry experiment" ; rdfs:subClassOf obo:CIDO_0000051 . a rdfs:Class ; rdfs:label "Central Nervous System Viral Diseases [Disease/Finding]" ; rdfs:subClassOf , obo:DOID_934 . obo:PR_000007294 a rdfs:Class ; rdfs:label "coagulation factor X" ; rdfs:comment "A protein that is a translation product of the human F10 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:CHEBI_63332 a rdfs:Class ; rdfs:label "EC 3.1.3.1 (alkaline phosphatase) inhibitor" ; rdfs:comment "An EC 3.1.3.* (phosphoric monoester hydrolase) inhibitor that interferes with the action of alkaline phosphatase (EC 3.1.3.1)." ; rdfs:subClassOf obo:CHEBI_76775 . obo:PR_O43292 a rdfs:Class ; rdfs:label "glycosylphosphatidylinositol anchor attachment 1 protein (human)" ; rdfs:comment "A glycosylphosphatidylinositol anchor attachment 1 protein that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000008158 , obo:PR_000029067 . obo:GO_0072657 a rdfs:Class ; rdfs:label "protein localization to membrane" ; rdfs:comment "A process in which a protein is transported to, or maintained in, a specific location in a membrane." ; rdfs:subClassOf obo:GO_0034613 , obo:GO_0051641 . obo:GO_0006837 a rdfs:Class ; rdfs:label "serotonin transport" ; rdfs:comment "The directed movement of serotonin into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Serotonin (5-hydroxytryptamine) is a monoamine neurotransmitter occurring in the peripheral and central nervous systems." ; rdfs:subClassOf obo:GO_0006812 , obo:GO_0015844 , obo:GO_0015850 . a rdfs:Class ; rdfs:label "Skin and Connective Tissue Diseases [Disease/Finding]" ; rdfs:subClassOf . obo:CHEBI_5693 a rdfs:Class ; rdfs:label "hexachlorophene" ; rdfs:comment "An organochlorine compound that is diphenylmethane in which each of the phenyl groups is substituted by chlorines at positions 2, 3, and 5, and by a hydroxy group at position 6. An antiseptic that is effective against Gram-positive organisms, it is used in soaps and creams for the treatment of various skin disorders. It is also used in agriculture as an acaricide and fungicide, but is not approved for such use within the European Union." ; rdfs:subClassOf obo:CHEBI_26195 , obo:CHEBI_27096 , obo:CHEBI_87039 . obo:CIDO_0000145 a rdf:Property ; rdfs:label "chemical inhibits in vitro invasion of virus"@en ; rdfs:comment "An object property that represents a relation between a chemical entity and a virus where the chemical has an effective role against viral invasion in vitro" ; rdfs:range ; rdfs:subPropertyOf obo:CIDO_0000149 , obo:CIDO_0000141 . obo:OPMI_0000093 a rdfs:Class ; rdfs:label "personal information"@en ; rdfs:comment "information associated with an individual" ; rdfs:subClassOf obo:IAO_0000030 . a rdfs:Class ; rdfs:label "Hydrazines [Chemical/Ingredient]" ; rdfs:subClassOf . obo:CIDO_0000186 a rdfs:Class ; rdfs:label "authorized COVID-19 teatment"@en ; rdfs:comment "A COVID-19 treatment that has been authorized by government for treating COVID-19 in a clinical setting" ; rdfs:subClassOf obo:CIDO_0000180 . obo:CIDO_0000012 a rdf:Property ; rdfs:label "treatment for"@en ; rdfs:comment "An object property that represents a relation between a material entity (e.g., drug or respirator) and a disease process where a drug is effective in treating a host against the disease process." ; rdfs:range . obo:PR_000005520 a rdfs:Class ; rdfs:label "CLIP-associating protein 1" ; rdfs:comment "A CLASP protein that is a translation product of the human CLASP1 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000050020 . obo:NCBITaxon_742006 a rdfs:Class ; rdfs:label "Bat SARS coronavirus HKU3-9" ; rdfs:subClassOf obo:NCBITaxon_442736 . obo:NCBITaxon_696098 a rdfs:Class ; rdfs:label "unclassified Betacoronavirus" ; rdfs:subClassOf obo:NCBITaxon_694002 . obo:NCBITaxon_385684 a rdfs:Class ; rdfs:label "SARS coronavirus CS24" ; rdfs:subClassOf obo:NCBITaxon_694009 . obo:CHEBI_35504 a rdfs:Class ; rdfs:label "addition compound" ; rdfs:comment "An addition compound contains two or more simpler compounds that can be packed in a definite ratio into a crystal. The term covers donor-acceptor complexes (adducts) and a variety of lattice compounds." ; rdfs:subClassOf obo:CHEBI_37577 . obo:CHEBI_33859 a rdfs:Class ; rdfs:label "aromatic carboxylic acid" ; rdfs:comment "Any carboxylic acid in which the carboxy group is directly bonded to an aromatic ring." ; rdfs:subClassOf obo:CHEBI_33575 , obo:CHEBI_33659 . obo:NCBITaxon_1699323 a rdfs:Class ; rdfs:label "Myotis Bat Alphacoronavirus strain YNXY_12C" ; rdfs:subClassOf obo:NCBITaxon_366617 . obo:PR_000005584 a rdfs:Class ; rdfs:label "dual specificity protein kinase CLK1" ; rdfs:comment "A protein that is a translation product of the human CLK1 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:CHEBI_5613 a rdfs:Class ; rdfs:label "haloperidol" ; rdfs:comment "A compound composed of a central piperidine structure with hydroxy and p-chlorophenyl substituents at position 4 and an N-linked p-fluorobutyrophenone moiety." ; rdfs:subClassOf obo:CHEBI_26878 , obo:CHEBI_37143 , obo:CHEBI_48590 , obo:CHEBI_76224 , obo:CHEBI_83403 . obo:CIDO_0000121 a rdf:Property ; rdfs:label "chemical has protein target as agonist"@en ; rdfs:comment "An object property that represents a relation between a chemical entity and a protein where the chemical entity can target the protein as an receptor agonist. Note that the chemical entity is usually an active compound of a corresponding drug. An agonist is a chemical that binds to a receptor and activates the receptor to produce a biological response." ; rdfs:range ; rdfs:subPropertyOf obo:CIDO_0000118 . obo:HP_0000271 a rdfs:Class ; rdfs:label "Abnormality of the face" ; rdfs:comment "An abnormality of the face." ; rdfs:subClassOf obo:HP_0000118 . obo:DOID_602 a rdfs:Class ; rdfs:label "cancerophobia" ; rdfs:subClassOf obo:DOID_0060048 . obo:NCBITaxon_749418 a rdfs:Class ; rdfs:label "Black-headed gull coronavirus CIR-66146" ; rdfs:subClassOf obo:NCBITaxon_749416 . obo:HP_0030972 a rdfs:Class ; rdfs:label "Abnormal systemic blood pressure" ; rdfs:comment "A chronic deviation from normal pressure in the systemic arterial system." ; rdfs:subClassOf obo:HP_0011025 . a rdfs:Class ; rdfs:label "Hepatitis D [Disease/Finding]" ; rdfs:subClassOf , . obo:PR_Q13443 a rdfs:Class ; rdfs:label "disintegrin and metalloproteinase domain-containing protein 9 (human)" ; rdfs:comment "A disintegrin and metalloproteinase domain-containing protein 9 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000003725 , obo:PR_000029067 . obo:NCBITaxon_321147 a rdfs:Class ; rdfs:label "SARS coronavirus BJ162" ; rdfs:subClassOf obo:NCBITaxon_694009 . obo:PR_P08581 a rdfs:Class ; rdfs:label "hepatocyte growth factor receptor (human)" ; rdfs:comment "A hepatocyte growth factor receptor that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000010335 , obo:PR_000029067 . obo:OPMI_0000470 a rdfs:Class ; rdfs:label "person ID"@en ; rdfs:comment "A centrally registered identifier that is uniquely assigned to a person." ; rdfs:subClassOf obo:IAO_0000578 . obo:NCBITaxon_864596 a rdfs:Class ; rdfs:label "Bat coronavirus BM48-31/BGR/2008" ; rdfs:subClassOf obo:NCBITaxon_2720068 . a rdfs:Class ; rdfs:label "Cellular Growth Phase Reduction [PE]" ; rdfs:subClassOf . obo:VO_0000600 a rdfs:Class ; rdfs:label "vaccinia virus vector" ; rdfs:comment "an orthopoxvirus vaccine vector that uses vaccinia virus as the vector" ; rdfs:subClassOf obo:VO_0001146 . obo:GO_0004364 a rdfs:Class ; rdfs:label "glutathione transferase activity" ; rdfs:comment "Catalysis of the reaction: R-X + glutathione = H-X + R-S-glutathione. R may be an aliphatic, aromatic or heterocyclic group; X may be a sulfate, nitrile or halide group." ; rdfs:subClassOf obo:GO_0003674 . obo:NCBITaxon_1269318 a rdfs:Class ; rdfs:label "Coronavirus BtCoV/OCR11/Pte_par/CRC/2011" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:CIDO_0020303 a rdfs:Class ; rdfs:label "TaqPath COVID-19 Combo Kit" ; rdfs:seeAlso ; rdfs:subClassOf obo:CIDO_0000454 . obo:PR_000050262 a rdfs:Class ; rdfs:label "severe acute respiratory syndrome coronavirus 2 protein" ; rdfs:comment "A protein that is encoded in the genome of Severe acute respiratory syndrome coronavirus 2." ; rdfs:subClassOf obo:PR_000036197 . a rdfs:Class ; rdfs:label "Enterobiasis [Disease/Finding]" ; rdfs:subClassOf . obo:NCBITaxon_681885 a rdfs:Class ; rdfs:label "Kenya bat coronavirus BtKY42" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:NCBITaxon_1503287 a rdfs:Class ; rdfs:label "BtMf-AlphaCoV/HuB2013-a" ; rdfs:subClassOf obo:NCBITaxon_366617 . obo:CHEBI_36388 a rdfs:Class ; rdfs:label "saturated organic heterocyclic parent" ; rdfs:subClassOf obo:CHEBI_35552 . obo:NCBITaxon_1679908 a rdfs:Class ; rdfs:label "Coronavirus RCoV/KS11_0514/Mic_arv/GER/2011" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:CHEBI_121828 a rdfs:Class ; rdfs:label "5-cyano-2-phenyl-6-[4-(2-pyridinyl)-1-piperazinyl]-3-pyridinecarboxylic acid ethyl ester" ; rdfs:subClassOf obo:CHEBI_26144 , obo:CHEBI_26421 . obo:CIDO_0000575 a rdfs:Class ; rdfs:label "ETFTVCADGFMPFLL" ; rdfs:comment "A coronavirus epitope that is part of some S protein from HCoV OC43 composed of the following amino acids ETFTVCADGFMPFLL" ; rdfs:subClassOf obo:CIDO_0000452 . obo:NCBITaxon_1338369 a rdfs:Class ; rdfs:label "Dipnotetrapodomorpha" ; rdfs:subClassOf obo:NCBITaxon_8287 . obo:CIDO_0000669 a rdfs:Class ; rdfs:label "F157- in SARS-CoV-2 S protein" ; rdfs:comment "An AA mutation or AA variant that has mutated an amino acid at position 157 into a deletion" ; rdfs:subClassOf obo:CIDO_0001144 . obo:NCBITaxon_1679897 a rdfs:Class ; rdfs:label "Coronavirus RCoV/D_RMU10_2066/Myo_gla/GER/2010" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:CIDO_0000695 a rdfs:Class ; rdfs:label "S477N in SARS-CoV-2 S protein" ; rdfs:comment "An AA mutation or AA variant that has mutated an amino acid at position 477 into a asparagine in S protein." ; rdfs:subClassOf obo:CIDO_0001157 . obo:CHEBI_49020 a rdfs:Class ; rdfs:label "hormone antagonist" ; rdfs:comment "A chemical substance which inhibits the function of the endocrine glands, the biosynthesis of their secreted hormones, or the action of hormones upon their specific sites." ; rdfs:subClassOf obo:CHEBI_48706 , obo:CHEBI_51061 . a rdfs:Class ; rdfs:label "Urethritis [Disease/Finding]" ; rdfs:subClassOf . obo:CHEBI_76730 a rdfs:Class ; rdfs:label "EC 1.4.* (oxidoreductase acting on donor CH-NH2 group) inhibitor" ; rdfs:comment "An oxidoreductase inhibitor which interferes with the action of an oxidoreductase acting on the CH-NH2 group of donors (EC 1.4.*.*)." ; rdfs:subClassOf obo:CHEBI_76725 . obo:CIDO_0000214 a rdfs:Class ; rdfs:label "SARS-CoV-2 S protein synthesis"@en ; rdfs:subClassOf obo:CIDO_0000213 . obo:HP_0011725 a rdfs:Class ; rdfs:label "Chaotic multifocal atrial tachycardia" ; rdfs:subClassOf obo:HP_0001692 . obo:CHEBI_33717 a rdfs:Class ; rdfs:label "C-terminal proteinogenic amino-acid residue" ; rdfs:comment "Any C-terminal alpha-amino-acid residue derived from a proteinogenic amino acid." ; rdfs:subClassOf obo:CHEBI_33700 , obo:CHEBI_33713 . obo:DOID_0050739 a rdfs:Class ; rdfs:label "autosomal genetic disease" ; rdfs:comment "A monogenic disease that has_material_basis_in a mutation in a single gene on one of the non-sex chromosomes." ; rdfs:subClassOf obo:DOID_0050177 . obo:GO_0071383 a rdfs:Class ; rdfs:label "cellular response to steroid hormone stimulus" ; rdfs:comment "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a steroid hormone stimulus." ; rdfs:subClassOf obo:GO_0032870 , obo:GO_0048545 , obo:GO_0071396 , obo:GO_0071407 . obo:PR_000008644 a rdfs:Class ; rdfs:label "heme oxygenase 1" ; rdfs:comment "A protein that is a translation product of the human HMOX1 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . a rdfs:Class ; rdfs:label "Thrombocythemia, Essential [Disease/Finding]" ; rdfs:subClassOf , , . obo:PR_Q13555 a rdfs:Class ; rdfs:label "calcium/calmodulin-dependent protein kinase type II subunit gamma (human)" ; rdfs:comment "A calcium/calmodulin-dependent protein kinase type II subunit gamma that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000003202 , obo:PR_000029067 . obo:PR_P00492 a rdfs:Class ; rdfs:label "hypoxanthine-guanine phosphoribosyltransferase (human)" ; rdfs:comment "A hypoxanthine-guanine phosphoribosyltransferase that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000008735 , obo:PR_000029067 . obo:NCBITaxon_1508225 a rdfs:Class ; rdfs:label "Lushi Ml bat coronavirus" ; rdfs:subClassOf obo:NCBITaxon_2691591 . obo:PR_000006961 a rdfs:Class ; rdfs:label "eIF-2-alpha kinase GCN2" ; rdfs:comment "A protein that is a translation product of the human EIF2AK4 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . a rdfs:Class ; rdfs:label "Tachycardia [Disease/Finding]" ; rdfs:subClassOf . obo:PR_000006870 a rdfs:Class ; rdfs:label "3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase" ; rdfs:comment "A protein that is a translation product of the human EBP gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . a rdfs:Class ; rdfs:label "PROMETHAZINE" ; rdfs:subClassOf . obo:CIDO_0020005 a rdfs:Class ; rdfs:label "Accula SARS-CoV-2 test" ; rdfs:seeAlso ; rdfs:subClassOf obo:CIDO_0000454 . obo:VO_0005110 a rdfs:Class ; rdfs:label "SARS ADS-MVA vaccine" ; rdfs:comment "A SARS recombinant vector vaccine that is made from a recombinant live-attenuated modified vaccinia virus Ankara (MVA) that had a full-length SARS-CoV envelope Spike (S) glycoprotein gene introduced into the deletion III region of the MVA genome." ; rdfs:subClassOf obo:VO_0012183 . obo:CIDO_0000161 a rdfs:Class ; rdfs:label "contact and droplet transmission of SARS-CoV-2"@en ; rdfs:subClassOf obo:CIDO_0000156 . obo:PR_P34903 a rdfs:Class ; rdfs:label "gamma-aminobutyric acid receptor subunit alpha-3 (human)" ; rdfs:comment "A gamma-aminobutyric acid receptor subunit alpha-3 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000007768 , obo:PR_000029067 . a rdfs:Class ; rdfs:label "Cholinergic Interactions [MoA]" ; rdfs:subClassOf . a rdfs:Class ; rdfs:label "Skin Diseases [Disease/Finding]" ; rdfs:subClassOf . obo:PR_Q9NVH1 a rdfs:Class ; rdfs:label "DnaJ homolog subfamily C member 11 (human)" ; rdfs:comment "A DnaJ homolog subfamily C member 11 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000029067 , obo:PR_000032183 . a rdfs:Class ; rdfs:label "Adrenergic alpha-Antagonists [MoA]" ; rdfs:subClassOf . obo:NCBITaxon_2591231 a rdfs:Class ; rdfs:label "Coronavirus BtSk-AlphaCoV/GX2018D" ; rdfs:subClassOf obo:NCBITaxon_2691591 . obo:PR_000024990 a rdfs:Class ; rdfs:label "type II interferon" ; rdfs:comment "A protein that binds to a specific cell surface receptor complex known as the IFN-gamma receptor (IFNGR), a complex of two IFNGR1 and two IFNGR2 chains." ; rdfs:subClassOf obo:PR_000000001 . obo:CHEBI_37143 a rdfs:Class ; rdfs:label "organofluorine compound" ; rdfs:comment "An organofluorine compound is a compound containing at least one carbon-fluorine bond." ; rdfs:subClassOf obo:CHEBI_17792 , obo:CHEBI_24062 , obo:CHEBI_36684 . obo:OBI_0002549 a rdfs:Class ; rdfs:label "ovary specimen" ; rdfs:comment "A specimen that is derived from female gonad." ; rdfs:subClassOf obo:OBI_0001479 . obo:CHEBI_33599 a rdfs:Class ; rdfs:label "spiro compound" ; rdfs:comment "A compound having one atom as the only common member of two rings." ; rdfs:subClassOf obo:CHEBI_33635 . obo:NCBITaxon_1788463 a rdfs:Class ; rdfs:label "Miniopterus bat coronavirus BtCoV/3736-1" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:CIDO_0000366 a rdfs:Class ; rdfs:label "protective clothing"@en ; rdfs:comment "clothing designed to protect the wearer's body from injury or infection." ; rdfs:subClassOf obo:CIDO_0000365 . obo:CIDO_0000878 a rdfs:Class ; rdfs:label "SARS-CoV2 nsp4 protein binding to human IDE" ; rdfs:comment "SARS-CoV2 nsp4 protein binding to human IDE, as evidented by an affinity-purification mass spectrometry experiment" ; rdfs:subClassOf obo:CIDO_0000581 . obo:GO_0043279 a rdfs:Class ; rdfs:label "response to alkaloid" ; rdfs:comment "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an alkaloid stimulus. Alkaloids are a large group of nitrogenous substances found in naturally in plants, many of which have extracts that are pharmacologically active." ; rdfs:subClassOf obo:GO_0010243 . obo:PR_000000043 a rdfs:Class ; rdfs:label "E3 ubiquitin-protein ligase RBX1" ; rdfs:comment "A RING-box protein 1 related protein that is a translation product of the human RBX1 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000027961 . obo:CHEBI_167098 a rdfs:Class ; rdfs:label "N-(fatty acyl)-ethanolamine" ; rdfs:comment "an N-acyl-ethanolamine where the acyl group is a fatty acyl chain with composition not specified, major species at pH 7.3." ; rdfs:subClassOf obo:CHEBI_29348 , obo:CHEBI_52640 . obo:CIDO_0000430 a rdfs:Class ; rdfs:label "COVID-19 diagnosis conclusion"@en ; rdfs:comment "The representation of a conclusion of a diagnostic process for the COVID-19 coronavirus disease." ; rdfs:subClassOf obo:CIDO_0000427 . obo:NCBITaxon_230236 a rdfs:Class ; rdfs:label "Porcine hemagglutinating encephalomyelitis virus (strain IAF-404)" ; rdfs:subClassOf obo:NCBITaxon_42005 . obo:PR_000012661 a rdfs:Class ; rdfs:label "phosphorylase b kinase gamma catalytic chain, skeletal muscle isoform" ; rdfs:comment "A protein that is a translation product of the human PHKG1 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:UBERON_0000948 a rdfs:Class ; rdfs:label "heart" ; rdfs:comment "A myogenic muscular circulatory organ found in the vertebrate cardiovascular system composed of chambers of cardiac muscle. It is the primary circulatory organ." ; rdfs:subClassOf obo:UBERON_0000465 , obo:UBERON_0003103 , obo:UBERON_0004120 , obo:UBERON_0005181 , obo:UBERON_0010314 . obo:CIDO_0000037 a rdfs:Class ; rdfs:label "COVID-19 diagnostic process using real time RT-PCR"@en ; rdfs:comment "A COVID-19 diagnostic process that uses a real time RT-PCR test" ; rdfs:subClassOf obo:CIDO_0000439 . a rdfs:Class ; rdfs:label "Schizophrenia [Disease/Finding]" ; rdfs:subClassOf . obo:CIDO_0000078 a rdfs:Class ; rdfs:label "chemical role against SARS-CoV entry"@en ; rdfs:subClassOf obo:CIDO_0000076 . obo:PR_000005448 a rdfs:Class ; rdfs:label "chondroitin sulfate synthase 2" ; rdfs:comment "A protein that is a translation product of the human CHPF gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . a rdfs:Class ; rdfs:label "BENZTROPINE" ; rdfs:subClassOf . obo:CIDO_0001106 a rdfs:Class ; rdfs:label "SARS-CoV2 orf8 protein binding to human ITGB1" ; rdfs:comment "SARS-CoV2 orf8 protein binding to human ITGB1, as evidented by an affinity-purification mass spectrometry experiment" ; rdfs:subClassOf obo:CIDO_0000051 . obo:CIDO_0000787 a rdfs:Class ; rdfs:label "SARS-CoV2 N protein binding to human RPL36" ; rdfs:comment "SARS-CoV2 N protein binding to human RPL36, as evidented by an affinity-purification mass spectrometry experiment" ; rdfs:subClassOf obo:CIDO_0000056 . obo:CHEBI_6444 a rdfs:Class ; rdfs:label "Levorphanol" ; rdfs:subClassOf obo:CHEBI_25418 . obo:OGG_2060009606 a rdfs:Class ; rdfs:label "protein-coding gene of Homo sapiens" ; rdfs:comment "A gene of Homo sapiens that has a protein-coding gene disposition" ; rdfs:subClassOf obo:OGG_2000009606 . obo:VO_0005085 a rdfs:Class ; rdfs:label "VAT00002"@en ; rdfs:comment "A stabilised pre-fusion SARS-CoV-2 spike protein vaccine produced in a baculovirus expression system and manufactured by Sanofi Pasteur and GlaxoSmithKline" ; rdfs:subClassOf obo:VO_0005202 . obo:PR_P17181 a rdfs:Class ; rdfs:label "interferon alpha/beta receptor 1 (human)" ; rdfs:comment "An interferon-alpha/beta receptor alpha chain that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000008922 , obo:PR_000029067 . obo:NCBITaxon_2018513 a rdfs:Class ; rdfs:label "Porcine enteric alphacoronavirus" ; rdfs:subClassOf obo:NCBITaxon_693998 . a rdfs:Class ; rdfs:label "Hepatic Metabolism [PK]" ; rdfs:subClassOf . obo:PR_000050387 a rdfs:Class ; rdfs:label "N gene translation product (SARS-CoV-2)" ; rdfs:comment "A protein that is a translation product of the N gene in SARS-CoV-2." ; rdfs:subClassOf obo:PR_000050262 . obo:NCBITaxon_1284374 a rdfs:Class ; rdfs:label "Bat coronavirus BtCoV/UKR-G17/Pip_nat/UKR/2011" ; rdfs:subClassOf obo:NCBITaxon_696098 . obo:PR_000002349 a rdfs:Class ; rdfs:label "serine/threonine-protein kinase 24" ; rdfs:comment "A serine/threonine-protein kinase, MST4-like that is a translation product of the human STK24 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000002212 . obo:NCBITaxon_931900 a rdfs:Class ; rdfs:label "Alphacoronavirus Eptesicus fuscus/Appalachian Ridge/P1-239577/IT/USA/2009" ; rdfs:subClassOf obo:NCBITaxon_366617 . obo:VO_0005176 a rdfs:Class ; rdfs:label "COH04S1"@en ; rdfs:comment "A synthetic modified vaccinia Ankara (MVA)-based SARS-CoV-2 vaccine" ; rdfs:subClassOf obo:VO_0005199 . obo:CHEBI_27376 a rdfs:Class ; rdfs:label "methanesulfonic acid" ; rdfs:comment "An alkanesulfonic acid in which the alkyl group directly linked to the sulfo functionality is methyl." ; rdfs:subClassOf obo:CHEBI_47901 , obo:CHEBI_64708 . obo:CHEBI_47019 a rdfs:Class ; rdfs:label "dihydroxytetrahydrofuran" ; rdfs:subClassOf obo:CHEBI_47017 . obo:CHEBI_32775 a rdfs:Class ; rdfs:label "D-tyrosinium" ; rdfs:comment "An optically active form of tyrosinium having D-configuration." ; rdfs:subClassOf obo:CHEBI_32786 . a rdfs:Class ; rdfs:label "Urologic Neoplasms [Disease/Finding]" ; rdfs:subClassOf . obo:PR_Q9Y5J6 a rdfs:Class ; rdfs:label "mitochondrial import inner membrane translocase subunit Tim10 B (human)" ; rdfs:comment "A mitochondrial import inner membrane translocase subunit Tim9 B that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000007709 , obo:PR_000029067 . obo:PR_000012759 a rdfs:Class ; rdfs:label "presequence protease, mitochondrial" ; rdfs:comment "A protein that is a translation product of the human PITRM1 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:VO_0004905 a rdfs:Class ; rdfs:label "MERS-CoV S protein with alum and CpG adjuvant"@en ; rdfs:subClassOf obo:VO_0004900 . obo:PR_Q96A26 a rdfs:Class ; rdfs:label "protein FAM162A (human)" ; rdfs:comment "A protein FAM162A that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000029067 , obo:PR_000030353 . obo:GO_1902186 a rdfs:Class ; rdfs:label "obsolete regulation of viral release from host cell" ; rdfs:comment "OBSOLETE. Any process that modulates the frequency, rate or extent of viral release from host cell." . obo:CHEBI_32613 a rdfs:Class ; rdfs:label "isoleucinium" ; rdfs:subClassOf obo:CHEBI_33719 . obo:CHEBI_62499 a rdfs:Class ; rdfs:label "methyl-branched fatty acid" ; rdfs:comment "Any branched-chain fatty acid containing methyl branches only." ; rdfs:subClassOf obo:CHEBI_35819 . obo:PR_Q96CW5 a rdfs:Class ; rdfs:label "gamma-tubulin complex component 3 (human)" ; rdfs:comment "A gamma-tubulin complex component 3 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000016828 , obo:PR_000029067 . obo:CIDO_0000836 a rdfs:Class ; rdfs:label "SARS-CoV2 nsp13 protein binding to human ERC1" ; rdfs:comment "SARS-CoV2 nsp13 protein binding to human ERC1, as evidented by an affinity-purification mass spectrometry experiment" ; rdfs:subClassOf obo:CIDO_0000058 . a rdfs:Class ; rdfs:label "Conduction System Depolarization [PE]" ; rdfs:subClassOf . obo:DRON_00022418 a rdfs:Class ; rdfs:label "mercaptopurine Oral Tablet" ; rdfs:subClassOf obo:DRON_00000022 . obo:CIDO_0000991 a rdfs:Class ; rdfs:label "SARS-CoV2 orf8 protein binding to human COL6A1" ; rdfs:comment "SARS-CoV2 orf8 protein binding to human COL6A1, as evidented by an affinity-purification mass spectrometry experiment" ; rdfs:subClassOf obo:CIDO_0000051 . obo:NCBITaxon_502108 a rdfs:Class ; rdfs:label "Bovine respiratory coronavirus AH187" ; rdfs:subClassOf obo:NCBITaxon_11128 . obo:NCBITaxon_1503303 a rdfs:Class ; rdfs:label "BtRs-BetaCoV/YN2013" ; rdfs:subClassOf obo:NCBITaxon_694009 . obo:PR_000010157 a rdfs:Class ; rdfs:label "mitogen-activated protein kinase 4" ; rdfs:comment "A protein that is a translation product of the human MAPK4 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:PR_000008110 a rdfs:Class ; rdfs:label "guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5" ; rdfs:comment "A protein that is a translation product of the human GNG5 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:NCBITaxon_681873 a rdfs:Class ; rdfs:label "Kenya bat coronavirus BtKY28" ; rdfs:subClassOf obo:NCBITaxon_2664420 . a rdfs:Class ; rdfs:label "Tachycardia, Supraventricular [Disease/Finding]" ; rdfs:subClassOf . obo:CIDO_0000207 a rdfs:Class ; rdfs:label "SARS-CoV-2 RTC proofreading"@en ; rdfs:subClassOf obo:CIDO_0000197 , obo:CIDO_0000203 . obo:NCBITaxon_305402 a rdfs:Class ; rdfs:label "SARS coronavirus A013" ; rdfs:subClassOf obo:NCBITaxon_694009 . obo:CHEBI_36340 a rdfs:Class ; rdfs:label "fermion" ; rdfs:comment "Particle of half-integer spin quantum number following Fermi-Dirac statistics. Fermions are named after Enrico Fermi." ; rdfs:subClassOf obo:CHEBI_36342 . obo:PR_000004437 a rdfs:Class ; rdfs:label "sodium/potassium-transporting ATPase subunit alpha-3" ; rdfs:comment "A protein that is a translation product of the human ATP1A3 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:GO_0055085 a rdfs:Class ; rdfs:label "transmembrane transport" ; rdfs:comment "The process in which a solute is transported across a lipid bilayer, from one side of a membrane to the other." ; rdfs:subClassOf obo:GO_0006810 , obo:GO_0009987 . obo:CHEBI_33424 a rdfs:Class ; rdfs:label "sulfur oxoacid derivative" ; rdfs:subClassOf obo:CHEBI_26835 , obo:CHEBI_33241 . obo:DRON_00018985 a rdfs:Class ; rdfs:label "nilotinib" ; rdfs:subClassOf obo:OBI_0000047 . obo:CIDO_0000128 a rdf:Property ; rdfs:label "drug has protein target as antagonist"@en ; rdfs:comment "An object property that represents a relation between a drug and a protein where the drug can target the protein as an receptor antagonist." ; rdfs:range ; rdfs:subPropertyOf obo:CIDO_0000124 . obo:NCBITaxon_9834 a rdfs:Class ; rdfs:label "Tylopoda" ; rdfs:subClassOf obo:NCBITaxon_91561 . obo:OAE_0003690 a rdfs:Class ; rdfs:label "Grade 1 myocarditis AE" ; rdfs:comment "a myocarditis AE that has asymptomatic with laboratory (e.g., BNP [B-Natriuretic Peptide ]) or cardiac imaging abnormalities" ; rdfs:subClassOf obo:OAE_0001201 . obo:CHEBI_28802 a rdfs:Class ; rdfs:label "flavonols" ; rdfs:comment "Any hydroxyflavone in which is the ring hydrogen at position 3 of the heterocyclic ring is replaced by a hydroxy group." ; rdfs:subClassOf obo:CHEBI_24698 . obo:PR_000016131 a rdfs:Class ; rdfs:label "TANK-binding kinase 1-binding protein 1" ; rdfs:comment "A protein that is a translation product of the human TBKBP1 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . a rdfs:Class ; rdfs:label "Benzodiazepines [Chemical/Ingredient]" ; rdfs:subClassOf . obo:NCBITaxon_34989 a rdfs:Class ; rdfs:label "Colubroidea" ; rdfs:subClassOf obo:NCBITaxon_8570 . obo:DRON_00819888 a rdfs:Class ; rdfs:label "fostamatinib" ; rdfs:subClassOf obo:OBI_0000047 . obo:CIDO_0000444 a rdfs:Class ; rdfs:label "HCoV 229E protein"@en ; rdfs:subClassOf obo:CIDO_0000440 , obo:PR_000000001 . obo:PR_000001484 a rdfs:Class ; rdfs:label "low affinity immunoglobulin gamma Fc region receptor III-A" ; rdfs:comment "An immunoglobulin gamma Fc receptor II/III/IV that is a translation product of the human FCGR3A gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000001355 . obo:CHEBI_145796 a rdfs:Class ; rdfs:label "digitoxin(1-)" ; rdfs:comment "An organic anion that is the conjugate base of digitoxin resulting from the deprotonation of furanone moiety; major species at pH 7.3." ; rdfs:subClassOf obo:CHEBI_25696 . obo:HP_0001739 a rdfs:Class ; rdfs:label "Abnormal nasopharynx morphology" ; rdfs:comment "A structural anomaly of the nasopharynx." ; rdfs:subClassOf obo:HP_0000366 , obo:HP_0033151 . obo:CIDO_0020325 a rdfs:Class ; rdfs:label "ViroKey SARS-CoV-2 RT-PCR Test v2.0" ; rdfs:seeAlso ; rdfs:subClassOf obo:CIDO_0000454 . obo:DOID_251 a rdfs:Class ; rdfs:label "alcohol-induced mental disorder" ; rdfs:subClassOf obo:DOID_8646 . obo:CHEBI_32696 a rdfs:Class ; rdfs:label "argininium(1+)" ; rdfs:subClassOf obo:CHEBI_33719 . obo:PR_P13984 a rdfs:Class ; rdfs:label "general transcription factor IIF subunit 2 (human)" ; rdfs:comment "A general transcription factor IIF subunit 2 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000008316 , obo:PR_000029067 . obo:CIDO_0000308 a rdfs:Class ; rdfs:label "EDAIIVNDENSSIKV"@en ; rdfs:subClassOf obo:CIDO_0000450 . obo:PR_000005504 a rdfs:Class ; rdfs:label "citron Rho-interacting kinase" ; rdfs:comment "A protein that is a translation product of the human CIT gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:HP_0007378 a rdfs:Class ; rdfs:label "Neoplasm of the gastrointestinal tract" ; rdfs:comment "A tumor (abnormal growth of tissue) of the gastrointestinal tract." ; rdfs:subClassOf obo:HP_0002664 , obo:HP_0011024 . a rdfs:Class ; rdfs:label "Mood Disorders [Disease/Finding]" ; rdfs:subClassOf . obo:NCBITaxon_1906673 a rdfs:Class ; rdfs:label "Alphacoronavirus sp." ; rdfs:subClassOf obo:NCBITaxon_366617 . obo:NCBITaxon_1986198 a rdfs:Class ; rdfs:label "Coronaviridae sp." ; rdfs:subClassOf obo:NCBITaxon_1986197 . obo:CHEBI_39172 a rdfs:Class ; rdfs:label "monochloropyridine" ; rdfs:comment "A chloropyridine in which only one chlorine is attached to the pyridine ring." ; rdfs:subClassOf obo:CHEBI_39173 . obo:NCBITaxon_1288702 a rdfs:Class ; rdfs:label "Bat coronavirus POA/2012/G03" ; rdfs:subClassOf obo:NCBITaxon_366617 . obo:OBI_0002530 a rdfs:Class ; rdfs:label "adipose tissue specimen" ; rdfs:comment "A specimen that is derived from adipose tissue." ; rdfs:subClassOf obo:OBI_0001479 . obo:CHEBI_33558 a rdfs:Class ; rdfs:label "alpha-amino-acid anion" ; rdfs:comment "An amino-acid anion obtained by deprotonation of any alpha-amino acid." ; rdfs:subClassOf obo:CHEBI_37022 . obo:PR_000001044 a rdfs:Class ; rdfs:label "cystic fibrosis transmembrane conductance regulator" ; rdfs:comment "A chloride channel protein that is a translation product of the human CFTR gene or a 1:1 ortholog thereof. Involved in the transport of chloride ions. The characteristic domain composition of the functional isoform consists of two modules of a membrane-spanning domain (ABC transporter transmembrane region) followed by a nucleotide-binding domain (ABC transporter domains), separated by an intracellular regulatory domain (R-domain). It also contains a C-terminal PDZ-binding region. The R-domain is an inhibitory domain of CFTR, and phosphorylation of the R-domain removes this inhibition, allowing activation of chloride flux." ; rdfs:subClassOf obo:PR_000044678 . obo:CIDO_0000885 a rdfs:Class ; rdfs:label "SARS-CoV2 nsp5_C145A protein binding to human GPX1" ; rdfs:comment "SARS-CoV2 nsp5_C145A protein binding to human GPX1, as evidented by an affinity-purification mass spectrometry experiment" ; rdfs:subClassOf obo:CIDO_0000047 . obo:NCBITaxon_301047 a rdfs:Class ; rdfs:label "Canine coronavirus 1-71" ; rdfs:subClassOf obo:NCBITaxon_11153 . obo:CHEBI_16347 a rdfs:Class ; rdfs:label "(R)-carnitine" ; rdfs:comment "The (R)-enantiomer of carnitine." ; rdfs:subClassOf obo:CHEBI_17126 . obo:NCBITaxon_1160968 a rdfs:Class ; rdfs:label "Rabbit coronavirus HKU14" ; rdfs:subClassOf obo:NCBITaxon_2724078 . obo:HP_0005978 a rdfs:Class ; rdfs:label "Type II diabetes mellitus" ; rdfs:comment "A type of diabetes mellitus initially characterized by insulin resistance and hyperinsulinemia and subsequently by glucose interolerance and hyperglycemia." ; rdfs:subClassOf obo:HP_0000819 . obo:PR_Q5JTV8 a rdfs:Class ; rdfs:label "torsin-1A-interacting protein 1 (human)" ; rdfs:comment "A torsin-1A-interacting protein 1 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000016551 , obo:PR_000029067 . obo:GO_1901564 a rdfs:Class ; rdfs:label "organonitrogen compound metabolic process" ; rdfs:comment "The chemical reactions and pathways involving organonitrogen compound." ; rdfs:subClassOf obo:GO_0006807 , obo:GO_0071704 . obo:PR_000002124 a rdfs:Class ; rdfs:label "C-C motif chemokine 4" ; rdfs:comment "A C-C motif chemokine 3/4 that is a translation product of the human CCL4 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000001998 . obo:PATO_0001985 a rdfs:Class ; rdfs:label "frozen" ; rdfs:comment "A quality inhering in a bearer by virtue of the bearer's being kept below its freezing point." ; rdfs:subClassOf obo:PATO_0000146 . obo:GO_1903828 a rdfs:Class ; rdfs:label "negative regulation of protein localization" ; rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of a protein localization." ; rdfs:subClassOf obo:GO_0032880 , obo:GO_0048519 . obo:DOID_4543 a rdfs:Class ; rdfs:label "retrograde amnesia" ; rdfs:comment "An amnestic disorder that involves a loss of one's pre-existing memories to conscious recollection." ; rdfs:subClassOf obo:DOID_10914 . obo:CIDO_0001044 a rdfs:Class ; rdfs:label "SARS-CoV2 orf9c protein binding to human ABCC1" ; rdfs:comment "SARS-CoV2 orf9c protein binding to human ABCC1, as evidented by an affinity-purification mass spectrometry experiment" ; rdfs:subClassOf obo:CIDO_0000054 . obo:GO_0007623 a rdfs:Class ; rdfs:label "circadian rhythm" ; rdfs:comment "Any biological process in an organism that recurs with a regularity of approximately 24 hours." ; rdfs:subClassOf obo:GO_0008150 . obo:NCBITaxon_1146859 a rdfs:Class ; rdfs:label "Bat coronavirus M.nattereri/UK/Wyt/1011A" ; rdfs:subClassOf obo:NCBITaxon_366617 . obo:NCBITaxon_305418 a rdfs:Class ; rdfs:label "SARS coronavirus C029" ; rdfs:subClassOf obo:NCBITaxon_694009 . obo:CHEBI_58588 a rdfs:Class ; rdfs:label "flavonol oxoanion" ; rdfs:comment "The conjugate base of a flavonol compound." ; rdfs:subClassOf obo:CHEBI_25696 . obo:CHEBI_76729 a rdfs:Class ; rdfs:label "EC 1.3.* (oxidoreductase acting on donor CH-CH group) inhibitor" ; rdfs:comment "An oxidoreductase inhibitor which interferes with the action of an oxidoreductase acting on the CH-CH group of donors (EC 1.3.*.*)." ; rdfs:subClassOf obo:CHEBI_76725 . obo:PR_000031651 a rdfs:Class ; rdfs:label "helicase MOV-10" ; rdfs:comment "A protein that is a translation product of the human MOV10 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:NCBITaxon_1415851 a rdfs:Class ; rdfs:label "Bat SARS-like coronavirus RsSHC014" ; rdfs:subClassOf obo:NCBITaxon_694009 . a rdfs:Class ; rdfs:label "Immunologic Deficiency Syndromes [Disease/Finding]" ; rdfs:subClassOf . obo:NCBITaxon_231427 a rdfs:Class ; rdfs:label "Avian infectious bronchitis virus (strain V18/91)" ; rdfs:subClassOf obo:NCBITaxon_11120 . obo:CIDO_0020027 a rdfs:Class ; rdfs:label "Aptima SARS-CoV-2/Flu assay" ; rdfs:seeAlso ; rdfs:subClassOf obo:CIDO_0000454 . obo:CHEBI_32914 a rdfs:Class ; rdfs:label "Cetylpyridinium" ; rdfs:comment "A pyridinium ion that has formula C21H38N." ; rdfs:subClassOf obo:CHEBI_50334 . obo:CHEBI_145498 a rdfs:Class ; rdfs:label "donepezil (1+)" ; rdfs:comment "A piperidinium ion resulting from the protonation of amino group of donepezil." ; rdfs:subClassOf obo:CHEBI_48633 . obo:CHEBI_62868 a rdfs:Class ; rdfs:label "hepatoprotective agent" ; rdfs:comment "Any compound that is able to prevent damage to the liver." ; rdfs:subClassOf obo:CHEBI_50267 . obo:NCBITaxon_447206 a rdfs:Class ; rdfs:label "Coronavirus group 2b" ; rdfs:subClassOf obo:NCBITaxon_696098 . obo:NCBITaxon_252654 a rdfs:Class ; rdfs:label "SARS coronavirus BJ302" ; rdfs:subClassOf obo:NCBITaxon_694009 . obo:CIDO_0000325 a rdfs:Class ; rdfs:label "VFNATRFASVYAWNR"@en ; rdfs:subClassOf obo:CIDO_0000314 . obo:CIDO_0000597 a rdfs:Class ; rdfs:label "AA variant in SARS-CoV-2 N protein LKR region"@en ; rdfs:subClassOf obo:CIDO_0000596 . obo:PR_P06401 a rdfs:Class ; rdfs:label "progesterone receptor (human)" ; rdfs:comment "A progesterone receptor that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000012621 , obo:PR_000029067 . obo:NCBITaxon_2492658 a rdfs:Class ; rdfs:label "Alphacoronavirus Bat-CoV/P.kuhlii/Italy/3398-19/2015" ; rdfs:subClassOf obo:NCBITaxon_2727852 . obo:UBERON_0018229 a rdfs:Class ; rdfs:label "renin-angiotensin system" ; rdfs:comment "A system consisting of renin, angiotensin-converting enzyme, and angiotensin II. Renin, an enzyme produced in the kidney, acts on angiotensinogen, an alpha-2 globulin produced by the liver, forming angiotensin I. The converting enzyme contained in the lung acts on angiotensin I in the plasma converting it to angiotensin II, the most powerful directly pressor substance known. It causes contraction of the arteriolar smooth muscle and has other indirect actions mediated through the adrenal cortex." ; rdfs:subClassOf obo:UBERON_0010000 . obo:PR_000014348 a rdfs:Class ; rdfs:label "reticulon-4" ; rdfs:comment "A protein that is a translation product of the human RTN4 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:NCBITaxon_258508 a rdfs:Class ; rdfs:label "SARS coronavirus ShanghaiQXC2" ; rdfs:subClassOf obo:NCBITaxon_694009 . obo:PR_000001971 a rdfs:Class ; rdfs:label "vascular endothelial growth factor receptor" ; rdfs:comment "A protein with core architecture consisting of a signal sequence, followed by 7 Ig-like domains (Pfam:PF00047, Pfam:PF07679, or Pfam:PF07686), a transmembrane region, and a cytoplasmic Protein tyrosine kinase domain." ; rdfs:subClassOf obo:PR_000000001 . obo:GO_0032502 a rdfs:Class ; rdfs:label "developmental process" ; rdfs:comment "A biological process whose specific outcome is the progression of an integrated living unit: an anatomical structure (which may be a subcellular structure, cell, tissue, or organ), or organism over time from an initial condition to a later condition." ; rdfs:subClassOf obo:GO_0008150 . obo:PR_000014305 a rdfs:Class ; rdfs:label "ribonucleoside-diphosphate reductase large subunit" ; rdfs:comment "A protein that is a translation product of the human RRM1 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:GO_0031279 a rdfs:Class ; rdfs:label "regulation of cyclase activity" ; rdfs:comment "Any process that modulates the frequency, rate or extent of cyclase activity." ; rdfs:subClassOf obo:GO_0050790 . obo:PR_P62937 a rdfs:Class ; rdfs:label "peptidyl-prolyl cis-trans isomerase A (human)" ; rdfs:comment "A peptidyl-prolyl cis-trans isomerase A that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000013075 , obo:PR_000029067 . obo:CHEBI_7553 a rdfs:Class ; rdfs:label "niclosamide" ; rdfs:comment "A secondary carboxamide resulting from the formal condensation of the carboxy group of 5-chlorosalicylic acid with the amino group of 2-chloro-4-nitroaniline. It is an oral anthelmintic drug approved for use against tapeworm infections." ; rdfs:subClassOf obo:CHEBI_140325 , obo:CHEBI_22702 , obo:CHEBI_35716 , obo:CHEBI_53468 , obo:CHEBI_83403 . a rdfs:Class ; rdfs:label "Lactones [Chemical/Ingredient]" ; rdfs:subClassOf . obo:CIDO_0000314 a rdfs:Class ; rdfs:label "SARS-CoV-2 S protein epitope"@en ; rdfs:subClassOf obo:CIDO_0000409 . obo:PR_000001578 a rdfs:Class ; rdfs:label "adenosine receptor A3" ; rdfs:comment "An adenosine receptor protein that is a translation product of the human ADORA3 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000001439 . obo:OGG_100010239 a rdfs:Class ; rdfs:label "genome of Viruses" ; rdfs:comment "The genome of an organism of Viruses" ; rdfs:subClassOf obo:OGG_0000000001 . obo:OGG_0000000014 a rdf:Property ; rdfs:label "is genome of organism"@en ; rdfs:comment "a 'part of continuant at some time' relation that incides a genome belongs to a organism. " ; rdfs:domain obo:BFO_0000001 ; rdfs:range obo:BFO_0000001 ; rdfs:subPropertyOf obo:BFO_0000050 . a rdfs:Class ; rdfs:label "Glycosides [Chemical/Ingredient]" ; rdfs:subClassOf . obo:PR_P49761 a rdfs:Class ; rdfs:label "dual specificity protein kinase CLK3 (human)" ; rdfs:comment "A dual specificity protein kinase CLK3 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000005586 , obo:PR_000029067 . obo:CIDO_0000971 a rdfs:Class ; rdfs:label "SARS-CoV2 orf10 protein binding to human ZYG11B" ; rdfs:comment "SARS-CoV2 orf10 protein binding to human ZYG11B, as evidented by an affinity-purification mass spectrometry experiment" ; rdfs:subClassOf obo:CIDO_0000050 . obo:VO_0004987 a rdfs:Class ; rdfs:label "Comirnaty" ; rdfs:comment "A SARS-CoV-2 RNA vaccine formed from a lipid nanoparticle-formulated trimerized SARS-CoV-2 receptor-binding domain" ; rdfs:subClassOf obo:VO_0005265 . obo:PR_P61019 a rdfs:Class ; rdfs:label "Ras-related protein Rab-2A (human)" ; rdfs:comment "A Ras-related protein Rab-2A that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000013603 , obo:PR_000029067 . obo:PR_P35348 a rdfs:Class ; rdfs:label "alpha-1A adrenergic receptor (human)" ; rdfs:comment "An alpha-1A adrenergic receptor that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000001183 , obo:PR_000029067 . obo:HP_0000118 a rdfs:Class ; rdfs:label "Phenotypic abnormality" ; rdfs:comment "A phenotypic abnormality." ; rdfs:subClassOf obo:BFO_0000019 . obo:NCBITaxon_694013 a rdfs:Class ; rdfs:label "Gammacoronavirus" ; rdfs:subClassOf obo:NCBITaxon_2501931 . obo:CHEBI_143079 a rdfs:Class ; rdfs:label "D-leucine zwitterion" ; rdfs:comment "A D-alpha-amino acid zwitterion arising from the transfer of a proton from the carboxy to the amino group of D-leucine; major species at pH 7.3." ; rdfs:subClassOf obo:CHEBI_59871 . obo:CHEBI_32530 a rdfs:Class ; rdfs:label "histidinate(2-)" ; rdfs:subClassOf obo:CHEBI_33558 . obo:PR_000029032 a rdfs:Class ; rdfs:label "Mus musculus protein" ; rdfs:comment "A protein that is encoded in the genome of Mus musculus." ; rdfs:subClassOf obo:PR_000036194 . obo:NCBITaxon_2749448 a rdfs:Class ; rdfs:label "Coronavirus cya-BetaCoV/2019" ; rdfs:subClassOf obo:NCBITaxon_1986197 . obo:CIDO_0000340 a rdfs:Class ; rdfs:label "APHGVVFLHVTYVPA"@en ; rdfs:subClassOf obo:CIDO_0000314 . obo:NCBITaxon_693999 a rdfs:Class ; rdfs:label "Scotophilus bat coronavirus 512" ; rdfs:subClassOf obo:NCBITaxon_2509505 . obo:CIDO_0020061 a rdfs:Class ; rdfs:label "Bio-Rad Reliance SARS-CoV-2/FluA/FluB RT-PCR Assay Kit" ; rdfs:seeAlso ; rdfs:subClassOf obo:CIDO_0000454 . obo:CHEBI_33703 a rdfs:Class ; rdfs:label "amino-acid cation" ; rdfs:subClassOf obo:CHEBI_33702 . obo:CIDO_0001165 a rdfs:Class ; rdfs:label "AA variant in SARS-CoV-2 S protein S2 TM region"@en ; rdfs:subClassOf obo:CIDO_0000595 . obo:NCBITaxon_903584 a rdfs:Class ; rdfs:label "Kenya bat coronavirus BtKY46" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:NCBITaxon_9397 a rdfs:Class ; rdfs:label "Chiroptera" ; rdfs:subClassOf obo:NCBITaxon_314145 . obo:NCBITaxon_1788421 a rdfs:Class ; rdfs:label "Bat coronavirus MfulBtCoV/3736-1" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:NCBITaxon_681859 a rdfs:Class ; rdfs:label "Kenya bat coronavirus BtKY12" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:OPMI_0000504 a rdfs:Class ; rdfs:label "DEA identifier"@en ; rdfs:comment "A centrally registered identifier that is issued by the Drug Enforcement Administration (DEA), a US federal agency, that allows a provider to write prescriptions for controlled substances." ; rdfs:subClassOf obo:IAO_0000578 . obo:VO_0000490 a rdfs:Class ; rdfs:label "immunization" ; rdfs:comment "immunization is a processual entity that primes or modifies an adaptivie immune response to some antigens." ; rdfs:subClassOf obo:BFO_0000015 . obo:CHEBI_70770 a rdfs:Class ; rdfs:label "Aurora kinase inhibitor" ; rdfs:comment "Any protein kinase inhibitor that inhibits the action of an Aurora kinase (a group of serine/threonine kinases that are essential for cell proliferation)." ; rdfs:subClassOf obo:CHEBI_37699 . obo:PR_Q9H093 a rdfs:Class ; rdfs:label "NUAK family SNF1-like kinase 2 (human)" ; rdfs:comment "A NUAK family SNF1-like kinase 2 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000011474 , obo:PR_000029067 . obo:CIDO_0000015 a rdfs:Class ; rdfs:label "diagnostic objective"@en ; rdfs:subClassOf obo:IAO_0000005 . obo:OBI_0000833 a rdf:Property ; rdfs:label "objective_achieved_by" ; rdfs:comment "This relation obtains between an objective specification and a planned process when the criteria specified in the objective specification are met at the end of the planned process." ; rdfs:domain obo:IAO_0000005 ; rdfs:range obo:OBI_0000011 . obo:CHEBI_35294 a rdfs:Class ; rdfs:label "carbopolycyclic compound" ; rdfs:comment "A polyclic compound in which all of the ring members are carbon atoms." ; rdfs:subClassOf obo:CHEBI_33598 , obo:CHEBI_35295 . obo:PR_000014199 a rdfs:Class ; rdfs:label "60S ribosomal protein L19" ; rdfs:comment "A protein that is a translation product of the human RPL19 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:PATO_0000169 a rdfs:Class ; rdfs:label "viability" ; rdfs:comment "An organismal quality inhering in a bearer or a population by virtue of the bearer's disposition to survive and develop normally or the number of surviving individuals in a given population." ; rdfs:subClassOf obo:PATO_0001237 , obo:PATO_0001995 . obo:CHEBI_35571 a rdfs:Class ; rdfs:label "mancude organic heterocyclic parent" ; rdfs:subClassOf obo:CHEBI_35552 , obo:CHEBI_35573 . obo:NCBITaxon_398811 a rdfs:Class ; rdfs:label "TGEV Purdue P115" ; rdfs:subClassOf obo:NCBITaxon_11151 . obo:CHEBI_7496 a rdfs:Class ; rdfs:label "nelfinavir" ; rdfs:comment "An aryl sulfide that is used (as its mesylate salt) for treatment of HIV and also exhibits some anticancer properties." ; rdfs:subClassOf obo:CHEBI_22702 , obo:CHEBI_27171 , obo:CHEBI_33853 , obo:CHEBI_35681 , obo:CHEBI_35683 , obo:CHEBI_50996 . a rdfs:Class ; rdfs:label "Autonomic Nervous System Activity Alteration [PE]" ; rdfs:subClassOf . obo:CHEBI_48378 a rdfs:Class ; rdfs:label "carboximidic acid" ; rdfs:subClassOf obo:CHEBI_35352 , obo:CHEBI_48377 . obo:NCBITaxon_227861 a rdfs:Class ; rdfs:label "SARS coronavirus Taiwan" ; rdfs:subClassOf obo:NCBITaxon_694009 . obo:NCBITaxon_2108211 a rdfs:Class ; rdfs:label "Rhinolophus pusillus coronavirus" ; rdfs:subClassOf obo:NCBITaxon_1986197 . obo:CIDO_0000539 a rdfs:Class ; rdfs:label "ICSASDMTNPDYTNL" ; rdfs:comment "A coronavirus epitope that is part of some S protein from HCoV OC43 composed of the following amino acids ICSASDMTNPDYTNL" ; rdfs:subClassOf obo:CIDO_0000452 . obo:CIDO_0020134 a rdfs:Class ; rdfs:label "Everlywell COVID-19 Test Home Collection Kit" ; rdfs:seeAlso ; rdfs:subClassOf obo:CIDO_0000455 . obo:NCBITaxon_497942 a rdfs:Class ; rdfs:label "Bat coronavirus M.dau/Germany/D7.3/2007" ; rdfs:subClassOf obo:NCBITaxon_366617 . obo:CIDO_0000182 a rdfs:Class ; rdfs:label "teatment with COVID-19 Convalescent Plasma"@en ; rdfs:comment "COVID-19 Convalescent Plasma (CCP) is proposed for use under an Emergency Use Authorization (EUA) under section 564 of the Federal Food, Drug, and Cosmetic Act (the Act),(21 USC 360bbb-3) as a passive immune therapy for the treatment of hospitalized patients with COVID-19." ; rdfs:subClassOf obo:CIDO_0000186 . obo:UBERON_0001037 a rdfs:Class ; rdfs:label "strand of hair" ; rdfs:comment "A filament, mostly protein, that grows from follicles found in the dermis[WP]." ; rdfs:subClassOf obo:UBERON_0000465 . obo:NCBITaxon_1679886 a rdfs:Class ; rdfs:label "Coronavirus RCoV/D_RMU10_1222/Mus_dom/GER/2010" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:CHEBI_24129 a rdfs:Class ; rdfs:label "furans" ; rdfs:comment "Compounds containing at least one furan ring." ; rdfs:subClassOf obo:CHEBI_25693 , obo:CHEBI_38104 . a rdfs:Class ; rdfs:label "Melanoma [Disease/Finding]" ; rdfs:subClassOf , . obo:NCBITaxon_1897071 a rdfs:Class ; rdfs:label "Bat coronavirus Car.per/1516/BRA/2011" ; rdfs:subClassOf obo:NCBITaxon_366617 . a rdfs:Class ; rdfs:label "Decreased Immunologically Active Biogenic Amine Activity [PE]" ; rdfs:subClassOf . obo:BFO_0000030 a rdfs:Class ; rdfs:label "object"@en ; rdfs:subClassOf obo:BFO_0000040 . obo:CIDO_0020009 a rdfs:Class ; rdfs:label "ADVIA Centaur IL6 assay" ; rdfs:subClassOf obo:CIDO_0000454 . obo:CHEBI_49103 a rdfs:Class ; rdfs:label "drug metabolite" ; rdfs:subClassOf obo:CHEBI_76967 . obo:PR_000016787 a rdfs:Class ; rdfs:label "dual specificity protein kinase TTK" ; rdfs:comment "A protein that is a translation product of the human TTK gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:CIDO_0020206 a rdfs:Class ; rdfs:label "MobileDetect Bio BCC19 (MD-Bio BCC19) Test Kit" ; rdfs:seeAlso ; rdfs:subClassOf obo:CIDO_0000454 . obo:GO_0006875 a rdfs:Class ; rdfs:label "cellular metal ion homeostasis" ; rdfs:comment "Any process involved in the maintenance of an internal steady state of metal ions at the level of a cell." ; rdfs:subClassOf obo:GO_0030003 , obo:GO_0055065 . obo:NCBITaxon_1415840 a rdfs:Class ; rdfs:label "Bat SARS-like coronavirus Rs4084" ; rdfs:subClassOf obo:NCBITaxon_2664420 . a rdfs:Class ; rdfs:label "Hepatic Excretion [PK]" ; rdfs:subClassOf . obo:CIDO_0020015 a rdfs:Class ; rdfs:label "Akron Children’s Hospital SARS-CoV-2 Assay" ; rdfs:seeAlso ; rdfs:subClassOf obo:CIDO_0000454 . obo:PR_000007132 a rdfs:Class ; rdfs:label "ephrin type-B receptor 4" ; rdfs:comment "An ephrin receptor that is a translation product of the human EPHB4 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000025845 . obo:PR_P17405 a rdfs:Class ; rdfs:label "sphingomyelin phosphodiesterase (human)" ; rdfs:comment "A sphingomyelin phosphodiesterase that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000015292 , obo:PR_000029067 . a rdfs:Class ; rdfs:label "MEFLOQUINE" ; rdfs:subClassOf . obo:DOID_1595 a rdfs:Class ; rdfs:label "endogenous depression" ; rdfs:comment "A mental depression that is characterized by a dysregulation of the endogenous opioid system and not of the monaminergic system." ; rdfs:subClassOf obo:DOID_1470 . obo:PR_Q9NQU5 a rdfs:Class ; rdfs:label "serine/threonine-protein kinase PAK 6 (human)" ; rdfs:comment "A serine/threonine-protein kinase PAK 6 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000012244 , obo:PR_000029067 . obo:CIDO_0020236 a rdfs:Class ; rdfs:label "Pixel by LabCorp COVID-19 Test Home Collection Kit" ; rdfs:seeAlso ; rdfs:subClassOf obo:CIDO_0000455 . obo:CHEBI_66980 a rdfs:Class ; rdfs:label "nootropic agent" ; rdfs:comment "Any compound that improves mental functions such as cognition, memory, intelligence, motivation, attention, and concentration." ; rdfs:subClassOf obo:CHEBI_23888 . obo:PR_000010144 a rdfs:Class ; rdfs:label "mitogen-activated protein kinase kinase kinase kinase 2" ; rdfs:comment "A protein that is a translation product of the human MAP4K2 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . a rdfs:Class ; rdfs:label "Triazoles [Chemical/Ingredient]" ; rdfs:subClassOf . obo:NCBITaxon_2724084 a rdfs:Class ; rdfs:label "unclassified Cegacovirus" ; rdfs:subClassOf obo:NCBITaxon_2509476 . obo:NCBITaxon_9681 a rdfs:Class ; rdfs:label "Felidae" ; rdfs:subClassOf obo:NCBITaxon_379583 . obo:CHEBI_24833 a rdfs:Class ; rdfs:label "oxoacid" ; rdfs:comment "A compound which contains oxygen, at least one other element, and at least one hydrogen bound to oxygen, and which produces a conjugate base by loss of positive hydrogen ion(s) (hydrons)." ; rdfs:subClassOf obo:CHEBI_24651 . obo:CIDO_0000780 a rdfs:Class ; rdfs:label "SARS-CoV2 N protein binding to human G3BP1" ; rdfs:comment "SARS-CoV2 N protein binding to human G3BP1, as evidented by an affinity-purification mass spectrometry experiment" ; rdfs:subClassOf obo:CIDO_0000056 . obo:UBERON_0001155 a rdfs:Class ; rdfs:label "colon" ; rdfs:comment "Last portion of the large intestine before it becomes the rectum." ; rdfs:subClassOf obo:UBERON_0000465 . obo:PR_Q52WX2 a rdfs:Class ; rdfs:label "serine/threonine-protein kinase SBK1 (human)" ; rdfs:comment "A serine/threonine-protein kinase SBK1 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000014475 , obo:PR_000029067 . obo:GENO_0000141 a rdfs:Class ; rdfs:subClassOf obo:BFO_0000144 . obo:CIDO_0000814 a rdfs:Class ; rdfs:label "SARS-CoV2 nsp12 protein binding to human SBNO1" ; rdfs:comment "SARS-CoV2 nsp12 protein binding to human SBNO1, as evidented by an affinity-purification mass spectrometry experiment" ; rdfs:subClassOf obo:CIDO_0000057 . obo:CIDO_0000333 a rdfs:Class ; rdfs:label "SFIEDLLFNKVTLAD"@en ; rdfs:subClassOf obo:CIDO_0000314 . obo:CHEBI_35790 a rdfs:Class ; rdfs:label "oxazole" ; rdfs:comment "An azole based on a five-membered heterocyclic aromatic skeleton containing one N and one O atom." ; rdfs:subClassOf obo:CHEBI_38104 , obo:CHEBI_68452 . obo:CIDO_0020212 a rdfs:Class ; rdfs:label "New York SARS-CoV Microsphere Immunoassay for Antibody Detection" ; rdfs:seeAlso ; rdfs:subClassOf obo:CIDO_0000454 . obo:PR_000000122 a rdfs:Class ; rdfs:label "Rho-related small GTPase" ; rdfs:comment "A small GTPase with a short insert (approximately 13 residues) coincident with loop 8 of Ras. This insert region forms a highly charged helix without dramatic disturbance of the global structure shared with other small GTPases. Rho-related small GTPases act as key transducers of extracellular signals to regulate the actin cytoskeleton, cell cycle progression and gene expression." ; rdfs:subClassOf obo:PR_000000028 . obo:CIDO_0000545 a rdfs:Class ; rdfs:label "YSFGRCPTSSIIKHP" ; rdfs:comment "A coronavirus epitope that is part of some S protein from HCoV HKU1 composed of the following amino acids YSFGRCPTSSIIKHP" ; rdfs:subClassOf obo:CIDO_0000409 . obo:NCBITaxon_1699346 a rdfs:Class ; rdfs:label "Myotis Bat Alphacoronavirus strain YNXY_5C" ; rdfs:subClassOf obo:NCBITaxon_366617 . obo:NCBITaxon_296841 a rdfs:Class ; rdfs:label "SARS coronavirus PC4-241" ; rdfs:subClassOf obo:NCBITaxon_694009 . obo:UBERON_3000016 a rdfs:Class ; rdfs:label "anterior nasal wall" ; rdfs:comment "Paired, vertical, and relatively straight plates that form the anterior limit of the nasal capsule." ; rdfs:subClassOf obo:UBERON_0000465 . obo:DRON_00023633 a rdfs:Class ; rdfs:label "Toremifene Oral Tablet" ; rdfs:subClassOf obo:DRON_00000022 . obo:CIDO_0000124 a rdf:Property ; rdfs:label "drug has protein target"@en ; rdfs:comment "An object property that represents a relation between a drug and a protein where the drug can target the protein." ; rdfs:range . obo:OMRSE_00000024 a rdfs:Class ; rdfs:label "role in human social processes"@en ; rdfs:comment "A role inhering in an entity realized by social interactions in human society."@en ; rdfs:subClassOf obo:BFO_0000023 . obo:HP_0012819 a rdfs:Class ; rdfs:label "Myocarditis" ; rdfs:comment "Inflammation of the myocardium." ; rdfs:subClassOf obo:HP_0001627 . obo:NCBITaxon_1269325 a rdfs:Class ; rdfs:label "Betacoronavirus BtCoV/KW2E-F53/Nyc_spec/GHA/2011" ; rdfs:subClassOf obo:NCBITaxon_696098 . obo:GO_0005248 a rdfs:Class ; rdfs:label "voltage-gated sodium channel activity" ; rdfs:comment "Enables the transmembrane transfer of a sodium ion by a voltage-gated channel. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded." ; rdfs:subClassOf obo:GO_0005272 . obo:OAE_0000660 a rdfs:Class ; rdfs:label "arrhythmia AE" ; rdfs:comment "a cardiac disorder AE which has an outcome of abnormal heart rhythm" ; rdfs:subClassOf obo:OAE_0000084 . obo:PR_P06280 a rdfs:Class ; rdfs:label "alpha-galactosidase A (human)" ; rdfs:comment "An alpha-galactosidase A that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000008015 , obo:PR_000029067 . obo:CIDO_0000956 a rdfs:Class ; rdfs:label "SARS-CoV2 nsp9 protein binding to human NUP214" ; rdfs:comment "SARS-CoV2 nsp9 protein binding to human NUP214, as evidented by an affinity-purification mass spectrometry experiment" ; rdfs:subClassOf obo:CIDO_0000583 . obo:CHEBI_51750 a rdfs:Class ; rdfs:label "alpha,beta-unsaturated carboxylic acid amide" ; rdfs:comment "A monocarboxylic amide of general formula R(1)R(2)C=CR(3)-C(=O)NR(4)R(5) or R(1)C#C-C(=O)NR(2)R(3) in which the amide C=O function is conjugated to an unsaturated C-C bond at the alpha,beta position." ; rdfs:subClassOf obo:CHEBI_37622 . obo:OAE_0000554 a rdfs:Class ; rdfs:label "abnormal digestion AE" ; rdfs:comment "a digestive system AE which has an outcome of abnormal digestion, which is an altered ability of the mechanical, chemical, and enzymatic processes of the body to convert ingested food into material suitable for assimilation for synthesis of tissues or liberation of energy" ; rdfs:subClassOf obo:OAE_0000439 . obo:GO_0030003 a rdfs:Class ; rdfs:label "cellular cation homeostasis" ; rdfs:comment "Any process involved in the maintenance of an internal steady state of cations at the level of a cell." ; rdfs:subClassOf obo:GO_0006873 , obo:GO_0055080 . obo:NCBITaxon_1737344 a rdfs:Class ; rdfs:label "SARS-like coronavirus BatCoV/BB9904/BGR/2008" ; rdfs:subClassOf obo:NCBITaxon_696098 . obo:NCBITaxon_745729 a rdfs:Class ; rdfs:label "Coronavirus M.das/VM3/2007/NLD" ; rdfs:subClassOf obo:NCBITaxon_696098 . obo:OPMI_0000517 a rdfs:Class ; rdfs:label "provenance of device record"@en ; rdfs:comment "A provenance of record that determines the provenance of the record, as in whether the record is from administrative claims or EHR." ; rdfs:subClassOf obo:OPMI_0000512 . obo:CHEBI_139556 a rdfs:Class ; rdfs:label "EC 4.1.1.17 (ornithine decarboxylase) inhibitor" ; rdfs:comment "An EC 4.1.1.* (carboxy-lyase) inhibitor that interferes with the action of ornithine decarboxylase (EC 4.1.1.17)." ; rdfs:subClassOf obo:CHEBI_76906 . obo:VO_0005236 a rdfs:Class ; rdfs:label "PTX-COVID19-B"@en ; rdfs:comment "A SARS-CoV-2 mRNA vaccine by Providence Therapeutics" ; rdfs:subClassOf obo:VO_0005198 . obo:NCBITaxon_766791 a rdfs:Class ; rdfs:label "Mink coronavirus strain WD1127" ; rdfs:subClassOf obo:NCBITaxon_1913642 . obo:CIDO_0000388 a rdfs:Class ; rdfs:label "transgenic mouse"@en ; rdfs:subClassOf obo:NCBITaxon_10090 . obo:NCBITaxon_2509474 a rdfs:Class ; rdfs:label "Buldecovirus" ; rdfs:subClassOf obo:NCBITaxon_1159901 . obo:CHEBI_32833 a rdfs:Class ; rdfs:label "threoninium" ; rdfs:subClassOf obo:CHEBI_33719 . a rdfs:Class ; rdfs:label "Decreased Central Nervous System Norepinephrine Activity [PE]" ; rdfs:subClassOf . a rdfs:Class ; rdfs:label "Pregnanes [Chemical/Ingredient]" ; rdfs:subClassOf . obo:VO_0005117 a rdfs:Class ; rdfs:label "Ad5.MERS-S vaccine" ; rdfs:comment "A MERS recombinant vector vaccine made of a recombinant adenoviral vector encoding the full-length MERS-CoV S protein (Ad5.MERS-S)" ; rdfs:subClassOf obo:VO_0004900 . obo:GO_1903900 a rdfs:Class ; rdfs:label "regulation of viral life cycle" ; rdfs:comment "Any process that modulates the frequency, rate or extent of viral life cycle." ; rdfs:subClassOf obo:GO_0050792 . obo:CIDO_0000653 a rdfs:Class ; rdfs:label "E92K in SARS-CoV-2 NS8 protein" ; rdfs:comment "An AA mutation or AA variant that has mutated an amino acid at position 92 into a lysine in ns8." ; rdfs:subClassOf obo:CIDO_0000617 . obo:CIDO_0000493 a rdfs:Class ; rdfs:label "ELSHWFKNQTSIAPN" ; rdfs:comment "A coronavirus epitope that is part of some S protein from HCoV HKU1 composed of the following amino acids ELSHWFKNQTSIAPN" ; rdfs:subClassOf obo:CIDO_0000450 . obo:VO_0004908 a rdfs:Class ; rdfs:label "COVID-19 vaccine"@en ; rdfs:comment "A coronavirus vaccine against the infection of SARS-CoV-2 (cause of COVID-19)" ; rdfs:subClassOf obo:VO_0004897 . obo:OBI_0001554 a rdfs:Class ; rdfs:label "rate measurement datum" ; rdfs:comment "A scalar measurement datum that represents the number of events occuring over a time interval" ; rdfs:subClassOf obo:IAO_0000032 . obo:IAO_0000004 a rdf:Property ; rdfs:label "has measurement value"@en ; rdfs:comment "A relation between a scalar measurement data item and a number that quantifies it." ; rdfs:domain obo:IAO_0000032 ; rdfs:range xsd:double . obo:IAO_0000039 a rdf:Property ; rdfs:label "has measurement unit label"@en ; rdfs:comment "A relation between a value specification and its unit of measurement." ; rdfs:range obo:IAO_0000003 ; rdfs:subPropertyOf obo:BFO_0000051 . obo:PR_000001095 a rdfs:Class ; rdfs:label "secretin-like G-protein coupled receptor" ; rdfs:comment "A G-protein coupled receptor that contains the 7 transmembrane receptor (secretin family) domain (Pfam:PF00002) and has an amino-terminal segment of about 50-80 residues that contains conserved disulfide bonds and participates in ligand binding." ; rdfs:subClassOf obo:PR_000030035 . obo:OPMI_0000557 a rdfs:Class ; rdfs:label "device exposure end date"@en ; rdfs:comment "The date on which a device exposure ends." ; rdfs:subClassOf obo:OPMI_0000556 . obo:PR_000007305 a rdfs:Class ; rdfs:label "fatty-acid amide hydrolase 1" ; rdfs:comment "A protein that is a translation product of the human FAAH gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:PR_000004758 a rdfs:Class ; rdfs:label "tyrosine-protein kinase BLK" ; rdfs:comment "A proto-oncogene SRC-like tyrosine-protein kinase that is a translation product of the human BLK gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000002997 . a rdfs:Class ; rdfs:label "Ovarian Follicular Phase Alteration [PE]" ; rdfs:subClassOf . obo:PR_Q8IWA5 a rdfs:Class ; rdfs:label "choline transporter-like protein 2 (human)" ; rdfs:comment "A choline transporter-like protein 2 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000015144 , obo:PR_000029067 . obo:CHEBI_76853 a rdfs:Class ; rdfs:label "EC 1.2.3.* (oxidoreductase acting on donor aldehyde/oxo group with oxygen as acceptor) inhibitor" ; rdfs:comment "An EC 1.2.* (oxidoreductase acting on donor aldehyde/oxo group) inhibitor that interferes with the action of any such enzyme using oxygen as acceptor (EC 1.2.3.*)." ; rdfs:subClassOf obo:CHEBI_76727 . obo:NCBITaxon_903573 a rdfs:Class ; rdfs:label "Kenya bat coronavirus BtKY105" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:PR_Q00765 a rdfs:Class ; rdfs:label "receptor expression-enhancing protein 5 (human)" ; rdfs:comment "A receptor expression-enhancing protein 5 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000013867 , obo:PR_000029067 . obo:CIDO_0000740 a rdfs:Class ; rdfs:label "T859N in SARS-CoV-2 S protein"@en ; rdfs:comment "An AA variant that has mutated an amino acid at position 859 into arginine in S protein." ; rdfs:subClassOf obo:CIDO_0000595 . obo:NCBITaxon_9615 a rdfs:Class ; rdfs:label "Canis lupus familiaris" ; rdfs:subClassOf obo:NCBITaxon_9612 . obo:NCBITaxon_1288688 a rdfs:Class ; rdfs:label "Bat coronavirus POA/2012/127" ; rdfs:subClassOf obo:NCBITaxon_366617 . obo:NCBITaxon_314146 a rdfs:Class ; rdfs:label "Euarchontoglires" ; rdfs:subClassOf obo:NCBITaxon_1437010 , obo:NCBITaxon_40674 . obo:CHEBI_43755 a rdfs:Class ; rdfs:label "lisinopril" ; rdfs:subClassOf obo:CHEBI_46761 . obo:CHEBI_67011 a rdfs:Class ; rdfs:label "folates" ; rdfs:comment "An N-acyl-L-alpha-amino acid anion obtained by deprotonation of any folic acid." ; rdfs:subClassOf obo:CHEBI_176842 , obo:CHEBI_59874 . obo:PR_000012241 a rdfs:Class ; rdfs:label "serine/threonine-protein kinase PAK 2" ; rdfs:comment "A protein that is a translation product of the human PAK2 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:PR_000050284 a rdfs:Class ; rdfs:label "RNA-directed RNA polymerase (SARS-CoV-2)" ; rdfs:comment "An ORF1ab proteolytic cleavage product (SARS-CoV-2) that is the central portion produced by the enzymatic action of 3CL-PRO proteinase (nsp5) when it cleaves the precursor replicase polyprotein 1ab (SARS-CoV-2) between residues 4392-4393 and 5324-5325. UniProtKB:P0DTD1, 4393-5324." ; rdfs:subClassOf obo:PR_000050283 . obo:CHEBI_25418 a rdfs:Class ; rdfs:label "morphinane alkaloid" ; rdfs:comment "An isoquinoline alkaloid based on a morphinan skeleton and its substituted derivatives." ; rdfs:subClassOf obo:CHEBI_24921 . obo:PR_000001482 a rdfs:Class ; rdfs:label "low affinity immunoglobulin gamma Fc region receptor II-c" ; rdfs:comment "An immunoglobulin gamma Fc receptor II/III/IV that is a translation product of the human FCGR2C gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000001355 . obo:PR_000015742 a rdfs:Class ; rdfs:label "serine/threonine-protein kinase 16" ; rdfs:comment "A protein that is a translation product of the human STK16 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:OBI_0002573 a rdfs:Class ; rdfs:label "polyA depleted RNA extract" ; rdfs:comment "A RNA extract that is the output of an extraction process in which RNA molecules lacking poly A tails at thier 3' ends are purified." ; rdfs:subClassOf obo:OBI_0000880 . obo:CHEBI_73416 a rdfs:Class ; rdfs:label "CB1 receptor antagonist" ; rdfs:comment "An antagonist that binds to and deactivates type 1 cannabinoid receptors." ; rdfs:subClassOf obo:CHEBI_73413 . obo:DRON_00020177 a rdfs:Class ; rdfs:label "darunavir" ; rdfs:subClassOf obo:OBI_0000047 . obo:NCBITaxon_1788461 a rdfs:Class ; rdfs:label "Miniopterus bat coronavirus BtCoV/3728-1" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:PR_000001617 a rdfs:Class ; rdfs:label "muscarinic acetylcholine receptor M5" ; rdfs:comment "A muscarinic acetylcholine receptor that is a translation product of the human CHRM5 gene or a 1:1 ortholog thereof. Its expression pattern is yet to be elucidated." ; rdfs:subClassOf obo:PR_000001488 . obo:NCBITaxon_864589 a rdfs:Class ; rdfs:label "Bat coronavirus BB98-15/BGR/2008" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:CHEBI_36809 a rdfs:Class ; rdfs:label "tricyclic antidepressant" ; rdfs:subClassOf obo:CHEBI_51959 . obo:CHEBI_77737 a rdfs:Class ; rdfs:label "dexverapamil(1+)" ; rdfs:comment "An ammonium ion resulting from the protonation of the tertiary amino group of dexverapamil." ; rdfs:subClassOf obo:CHEBI_35274 . obo:CIDO_0000916 a rdfs:Class ; rdfs:label "SARS-CoV2 nsp7 protein binding to human RAB8A" ; rdfs:comment "SARS-CoV2 nsp7 protein binding to human RAB8A, as evidented by an affinity-purification mass spectrometry experiment" ; rdfs:subClassOf obo:CIDO_0000049 . obo:HP_0025031 a rdfs:Class ; rdfs:label "Abnormality of the digestive system"@en ; rdfs:comment "Any anomaly of the digestive system, a collection of organs that is made up of the gastrointestinal tract and the liver, pancreas, and gallbladder. The gastrointestinal tract is a series of hollow organs joined in a long, twisting tube from the mouth to the anus, including the mouth, esophagus, stomach, small intestine, large intestine and anus." ; rdfs:subClassOf obo:HP_0000118 . obo:NCBITaxon_903570 a rdfs:Class ; rdfs:label "Kenya bat coronavirus BtKY102" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:PR_000014287 a rdfs:Class ; rdfs:label "ribosomal protein S6 kinase alpha-6" ; rdfs:comment "A ribosomal protein S6 kinase alpha that is a translation product of the human RPS6KA6 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000029187 . obo:CHEBI_25384 a rdfs:Class ; rdfs:label "monocarboxylic acid" ; rdfs:comment "An oxoacid containing a single carboxy group." ; rdfs:subClassOf obo:CHEBI_33575 . obo:CHEBI_24789 a rdfs:Class ; rdfs:label "indanones" ; rdfs:subClassOf obo:CHEBI_3992 , obo:CHEBI_46940 . obo:CHEBI_83925 a rdfs:Class ; rdfs:label "non-proteinogenic alpha-amino acid" ; rdfs:comment "Any alpha-amino acid which is not a member of the group of 23 proteinogenic amino acids." ; rdfs:subClassOf obo:CHEBI_33704 , obo:CHEBI_83820 . obo:CHEBI_71416 a rdfs:Class ; rdfs:label "phenazopyridine" ; rdfs:comment "A diaminopyridine that is 2,6-diaminopyridine substituted at position 3 by a phenylazo group. A local anesthetic that has topical analgesic effect on mucosa lining of the urinary tract. Its use is limited by problems with toxicity (primarily blood disorders) and potential carcinogenicity." ; rdfs:subClassOf obo:CHEBI_37533 , obo:CHEBI_51598 . obo:PR_Q6NXT6 a rdfs:Class ; rdfs:label "transmembrane anterior posterior transformation protein 1 homolog (human)" ; rdfs:comment "A transmembrane anterior posterior transformation protein 1 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000016055 , obo:PR_000029067 . obo:CIDO_0000405 a rdfs:Class ; rdfs:label "SARS-CoV-2 based on GISAID clades"@en ; rdfs:subClassOf obo:NCBITaxon_2697049 . obo:CHEBI_57248 a rdfs:Class ; rdfs:label "echinocandin" ; rdfs:comment "Any one of a family of large lipopeptides that are inhibitors of the enzyme 1,3-beta-glucan synthase, thus damaging fungal cell walls. Echinocandins are fungicidal against most Candida spp and fungistatic against Aspergillus spp." ; rdfs:subClassOf obo:CHEBI_46895 , obo:CHEBI_86478 . obo:NCBITaxon_272753 a rdfs:Class ; rdfs:label "Human coronavirus 3363/2000/NL" ; rdfs:subClassOf obo:NCBITaxon_277944 . obo:HP_0001250 a rdfs:Class ; rdfs:label "Seizure" ; rdfs:comment "A seizure is an intermittent abnormality of nervous system physiology characterised by a transient occurrence of signs and/or symptoms due to abnormal excessive or synchronous neuronal activity in the brain." ; rdfs:subClassOf obo:HP_0012638 . obo:CHEBI_63609 a rdfs:Class ; rdfs:label "Mefloquine" ; rdfs:comment "A racemate composed of (+)-(11R,2'S)- and (-)-(11S,2'R)-enantiomers of mefloquine. An antimalarial agent which acts as a blood schizonticide; its mechanism of action is unknown." ; rdfs:subClassOf obo:CHEBI_60911 . obo:GO_0003081 a rdfs:Class ; rdfs:label "regulation of systemic arterial blood pressure by renin-angiotensin" ; rdfs:comment "The process in which renin-angiotensin modulates the force with which blood passes through the circulatory system." ; rdfs:subClassOf obo:GO_0001990 . obo:PR_Q96JC1 a rdfs:Class ; rdfs:label "Vam6/Vps39-like protein (human)" ; rdfs:comment "A Vam6/Vps39-like protein that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000017339 , obo:PR_000029067 . obo:PR_O95070 a rdfs:Class ; rdfs:label "protein YIF1A (human)" ; rdfs:comment "A protein YIF1A that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000017529 , obo:PR_000029067 . a rdfs:Class ; rdfs:label "Harmine [Chemical/Ingredient]" ; rdfs:subClassOf , . obo:NCBITaxon_1532173 a rdfs:Class ; rdfs:label "Alphacoronavirus BtCoV/MSTM6/Min_nat/RSA/2010" ; rdfs:subClassOf obo:NCBITaxon_366617 . obo:CIDO_0020268 a rdfs:Class ; rdfs:label "Sampinute COVID-19 Antigen MIA" ; rdfs:seeAlso ; rdfs:subClassOf obo:CIDO_0000454 . obo:PR_P42679 a rdfs:Class ; rdfs:label "megakaryocyte-associated tyrosine-protein kinase (human)" ; rdfs:comment "A megakaryocyte-associated tyrosine-protein kinase that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000010204 , obo:PR_000029067 . obo:VO_0000415 a rdfs:Class ; rdfs:label "vaccine additive role" ; rdfs:subClassOf obo:VO_0000617 . obo:CIDO_0000197 a rdfs:Class ; rdfs:label "SARS-CoV-2 viral process to host"@en ; rdfs:comment "A SARS-CoV-2 viral process that causes the fusion of host cells into multinucleated syncytal complexes." ; rdfs:subClassOf obo:CIDO_0000195 , obo:CIDO_0000198 . obo:NCBITaxon_1699355 a rdfs:Class ; rdfs:label "Rousettus Bat Betacoronavirus strain ML_70I" ; rdfs:subClassOf obo:NCBITaxon_696098 . obo:HP_0011675 a rdfs:Class ; rdfs:label "Arrhythmia" ; rdfs:comment "Any cardiac rhythm other than the normal sinus rhythm. Such a rhythm may be either of sinus or ectopic origin and either regular or irregular. An arrhythmia may be due to a disturbance in impulse formation or conduction or both." ; rdfs:subClassOf obo:HP_0030956 . obo:CHEBI_29970 a rdfs:Class ; rdfs:label "D-lysinium residue" ; rdfs:subClassOf obo:CHEBI_32579 . obo:VO_0005391 a rdfs:Class ; rdfs:label "ABO1009-DP"@en ; rdfs:comment "A SARS-CoV-2 RNA vaccine by Suzhou Abogen Biosciences Co., Ltd." ; rdfs:subClassOf obo:VO_0005198 . a rdfs:Class ; rdfs:label "Nucleosides [Chemical/Ingredient]" ; rdfs:subClassOf , . obo:GO_0019725 a rdfs:Class ; rdfs:label "cellular homeostasis" ; rdfs:comment "Any process involved in the maintenance of an internal steady state at the level of the cell." ; rdfs:subClassOf obo:GO_0009987 , obo:GO_0042592 . obo:NCBITaxon_502101 a rdfs:Class ; rdfs:label "Feline coronavirus UU2" ; rdfs:subClassOf obo:NCBITaxon_12663 . obo:NCBITaxon_425243 a rdfs:Class ; rdfs:label "Bovine coronaviurus KV0516" ; rdfs:subClassOf obo:NCBITaxon_696098 . obo:UBERON_0000173 a rdfs:Class ; rdfs:label "amniotic fluid" ; rdfs:comment "Amniotic fluid is a bodily fluid consisting of watery liquid surrounding and cushioning a growing fetus within the amnion. It allows the fetus to move freely without the walls of the uterus being too tight against its body. Buoyancy is also provided. The composition of the fluid changes over the course of gestation. Initially, amniotic fluid is similar to maternal plasma, mainly water with electrolytes. As the fetus develops, proteins, carbohydrates, lipids, phospholipids originating from the lungs, fetal cells, and urea are deposited in the fluid." ; rdfs:subClassOf obo:UBERON_0000463 . obo:CHEBI_33853 a rdfs:Class ; rdfs:label "phenols" ; rdfs:comment "Organic aromatic compounds having one or more hydroxy groups attached to a benzene or other arene ring." ; rdfs:subClassOf obo:CHEBI_33659 , obo:CHEBI_33822 . obo:PR_000003554 a rdfs:Class ; rdfs:label "multidrug resistance-associated protein 1" ; rdfs:comment "A protein that is a translation product of the human ABCC1 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:PR_O95613 a rdfs:Class ; rdfs:label "pericentrin (human)" ; rdfs:comment "A pericentrin that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000012423 , obo:PR_000029067 . obo:PR_Q14289 a rdfs:Class ; rdfs:label "protein-tyrosine kinase 2-beta (human)" ; rdfs:comment "A focal adhesion kinase 2 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000003032 , obo:PR_000029067 . obo:CIDO_0020128 a rdfs:Class ; rdfs:label "Ellume COVID-19 Home Test" ; rdfs:seeAlso ; rdfs:subClassOf obo:CIDO_0000454 . obo:CHEBI_22492 a rdfs:Class ; rdfs:label "amino aldehyde" ; rdfs:comment "Any aldehyde which contains an amino group." ; rdfs:subClassOf obo:CHEBI_17478 . obo:GO_0050870 a rdfs:Class ; rdfs:label "positive regulation of T cell activation" ; rdfs:comment "Any process that activates or increases the frequency, rate or extent of T cell activation." ; rdfs:subClassOf obo:GO_0051249 , obo:GO_0051251 , obo:GO_1903039 . obo:CIDO_0000164 a rdfs:Class ; rdfs:label "infectious respiratory aerosol"@en ; rdfs:comment "Respiratory aerosols that contain infectious particles. Aerosol size is determined by the force and pressure involved in the generation of the particles. The final size depends on the nature of the fluid containing the organisms, the force and pressure at emission, the initial size of the aerosol, environmental conditions (e.g. temperature, relative humidity and airflow), the time spent airborne, and the size of the organisms within a droplet." ; rdfs:subClassOf obo:ENVO_00010505 . obo:CIDO_0000524 a rdfs:Class ; rdfs:label "NGSNILEAFTKPVFI" ; rdfs:comment "A coronavirus epitope that is part of some S protein from HCoV 229E composed of the following amino acids NGSNILEAFTKPVFI" ; rdfs:subClassOf obo:CIDO_0000451 . obo:NCBITaxon_284515 a rdfs:Class ; rdfs:label "Avian infectious bronchitis virus partridge/GD/S14/2003" ; rdfs:subClassOf obo:NCBITaxon_11120 . obo:DOID_150 a rdfs:Class ; rdfs:label "disease of mental health" ; rdfs:comment "A disease that involves a psychological or behavioral pattern generally associated with subjective distress or disability that occurs in an individual, and which are not a part of normal development or culture." ; rdfs:subClassOf obo:DOID_4 . obo:CHEBI_70781 a rdfs:Class ; rdfs:label "PPAR modulator" ; rdfs:comment "Any compound which acts on the peroxisome proliferator-activated receptor." ; rdfs:subClassOf obo:CHEBI_52210 . obo:PR_P82663 a rdfs:Class ; rdfs:label "28S ribosomal protein S25, mitochondrial (human)" ; rdfs:comment "A 28S ribosomal protein S25, mitochondrial that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000010633 , obo:PR_000029067 . a rdfs:Class ; rdfs:label "Cardanolides [Chemical/Ingredient]" ; rdfs:subClassOf . obo:PR_Q9NXA8 a rdfs:Class ; rdfs:label "NAD-dependent protein deacylase sirtuin-5, mitochondrial (human)" ; rdfs:comment "An NAD-dependent deacetylase sirtuin-5 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000014891 , obo:PR_000029067 . obo:NCBITaxon_2509503 a rdfs:Class ; rdfs:label "Nyctacovirus" ; rdfs:subClassOf obo:NCBITaxon_693996 . obo:NCBITaxon_1458241 a rdfs:Class ; rdfs:label "Betacoronavirus Eptesicus/13RS384_26/Italy/2012" ; rdfs:subClassOf obo:NCBITaxon_696098 . obo:NCBITaxon_2724078 a rdfs:Class ; rdfs:label "unclassified Embecovirus" ; rdfs:subClassOf obo:NCBITaxon_2509481 . a rdfs:Class ; rdfs:label "Hormone Receptor Agonists [MoA]" ; rdfs:subClassOf . obo:CHEBI_33658 a rdfs:Class ; rdfs:label "arene" ; rdfs:comment "Any monocyclic or polycyclic aromatic hydrocarbon." ; rdfs:subClassOf obo:CHEBI_33659 , obo:CHEBI_33663 . obo:CHEBI_67144 a rdfs:Class ; rdfs:label "2-(morpholin-4-yl)ethanol" ; rdfs:comment "A primary alcohol that is ethanol in which one of the methyl hydrogens is replaced by a morpholin-4-yl group." ; rdfs:subClassOf obo:CHEBI_15734 , obo:CHEBI_38785 , obo:CHEBI_50996 . obo:DRON_00021389 a rdfs:Class ; rdfs:label "Clomipramine Extended Release Tablet" ; rdfs:subClassOf obo:DRON_00000022 . obo:VO_0005276 a rdfs:Class ; rdfs:label "LNP-nCOV saRNA-02"@en ; rdfs:comment "A SARS-CoV-2 self-amplifying RNA vaccine sponsored by MRC/UVRI and LSHTM Uganda Research Unit" ; rdfs:subClassOf obo:VO_0005198 . a rdfs:Class ; rdfs:label "Cinnamates [Chemical/Ingredient]" ; rdfs:subClassOf . obo:NCBITaxon_756647 a rdfs:Class ; rdfs:label "Bovine coronavirus cow/WDBR-1275/BRA/2003" ; rdfs:subClassOf obo:NCBITaxon_11128 . a rdfs:Class ; rdfs:label "Cerebral Hemorrhage [Disease/Finding]" ; rdfs:subClassOf . a rdfs:Class ; rdfs:label "Neoplasms, Germ Cell and Embryonal [Disease/Finding]" ; rdfs:subClassOf . obo:CHEBI_17026 a rdfs:Class ; rdfs:label "progesterone" ; rdfs:comment "A C21-steroid hormone in which a pregnane skeleton carries oxo substituents at positions 3 and 20 and is unsaturated at C(4)-C(5). As a hormone, it is involved in the female menstrual cycle, pregnancy and embryogenesis of humans and other species." ; rdfs:subClassOf obo:CHEBI_36885 , obo:CHEBI_47909 , obo:CHEBI_64600 . obo:CIDO_0000122 a rdf:Property ; rdfs:label "chemical binds protein"@en ; rdfs:comment "An object property that represents a relation between a chemical entity and a protein where the chemical entity can target the protein as an binder that chemically binds to the targeted protein. Note that the chemical entity is usually an active compound of a corresponding drug." ; rdfs:range ; rdfs:subPropertyOf obo:CIDO_0000118 . obo:CIDO_0020220 a rdfs:Class ; rdfs:label "OMNIgene·ORAL OM-505 and OME-505 (OMNIgene·ORAL) saliva collection devices" ; rdfs:seeAlso ; rdfs:subClassOf obo:CIDO_0000455 . obo:GO_1901575 a rdfs:Class ; rdfs:label "organic substance catabolic process" ; rdfs:comment "The chemical reactions and pathways resulting in the breakdown of an organic substance, any molecular entity containing carbon." ; rdfs:subClassOf obo:GO_0009056 , obo:GO_0071704 . obo:HP_0001627 a rdfs:Class ; rdfs:label "Abnormal heart morphology" ; rdfs:comment "Any structural anomaly of the heart." ; rdfs:subClassOf obo:HP_0030680 . a rdfs:Class ; rdfs:label "Decreased Endocytosis [PE]" ; rdfs:subClassOf . obo:PR_P07477 a rdfs:Class ; rdfs:label "serine protease 1 (human)" ; rdfs:comment "A serine protease 1 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000013318 , obo:PR_000029067 . obo:GO_0071495 a rdfs:Class ; rdfs:label "cellular response to endogenous stimulus" ; rdfs:comment "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus arising within the organism." ; rdfs:subClassOf obo:GO_0009719 . obo:CHEBI_3049 a rdfs:Class ; rdfs:label "benzatropine mesylate" ; rdfs:comment "The methanesulfonate salt of benzatropine. An acetylcholine receptor antagonist, it is used in the treatment of Parkinson's disease, and to reduce parkinsonism and akathisia side effects of antipsychotic treatments." ; rdfs:subClassOf obo:CHEBI_38037 . obo:VO_0005157 a rdfs:Class ; rdfs:label "Moderna COVID-19 vaccine" ; rdfs:comment "A SARS-CoV2 RNA vaccine made of lipid nanoparticle with mRNA which encodes the S-2P antigen, made of the SARS-CoV-2 glycoprotein with a transmembrane anchor and intact S1-S2 cleavage site." ; rdfs:subClassOf obo:VO_0005265 . obo:CIDO_0000284 a rdfs:Class ; rdfs:label "viral life cycle stage"@en ; rdfs:comment "vial life cycle is the collection of the multiple steps involved in the virus processes occurring inside cells" ; rdfs:subClassOf obo:BFO_0000015 . obo:OBI_0302887 a rdfs:Class ; rdfs:label "staining"@en ; rdfs:comment "Staining is a process which results in the addition a class-specific (DNA, proteins, lipids, carbohydrates) dye to a substrate to qualify or quantify the presence of a specific compound."@en ; rdfs:subClassOf obo:OBI_0000094 . obo:NCBITaxon_1076421 a rdfs:Class ; rdfs:label "Alphacoronavirus N.las/G/Spain/2007" ; rdfs:subClassOf obo:NCBITaxon_366617 . obo:CHEBI_51422 a rdfs:Class ; rdfs:label "organodiyl group" ; rdfs:comment "Any organic substituent group, regardless of functional type, having two free valences at carbon atom(s)." ; rdfs:subClassOf obo:CHEBI_51446 . obo:PR_000017079 a rdfs:Class ; rdfs:label "serine/threonine-protein kinase ULK3" ; rdfs:comment "A protein that is a translation product of the human ULK3 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:PR_000000068 a rdfs:Class ; rdfs:label "activin receptor type-1B" ; rdfs:comment "A TGF-beta superfamily receptor type-1 that is a translation product of the human ACVR1B gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000006 . obo:CHEBI_46896 a rdfs:Class ; rdfs:label "diacyl lipopeptide" ; rdfs:subClassOf obo:CHEBI_46895 . obo:CIDO_0020338 a rdfs:Class ; rdfs:label "Xpert Xpress SARS-CoV-2 DoD" ; rdfs:seeAlso ; rdfs:subClassOf obo:CIDO_0000454 . obo:PR_000007185 a rdfs:Class ; rdfs:label "serine/threonine-protein kinase/endoribonuclease IRE1" ; rdfs:comment "A protein that is a translation product of the human ERN1 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:GO_0042417 a rdfs:Class ; rdfs:label "dopamine metabolic process" ; rdfs:comment "The chemical reactions and pathways involving dopamine, a catecholamine neurotransmitter and a metabolic precursor of noradrenaline and adrenaline." ; rdfs:subClassOf obo:GO_0006584 . obo:CHEBI_137982 a rdfs:Class ; rdfs:label "tertiary ammonium ion" ; rdfs:comment "An organic cation obtained by protonation of the amino group of any tertiary amino compound." ; rdfs:subClassOf obo:CHEBI_25697 . obo:CIDO_0000085 a rdfs:Class ; rdfs:label "coronaviral entry to cell"@en ; rdfs:comment "A coronavirus-host interaction by which the virus enters the host cell" ; rdfs:subClassOf obo:CIDO_0000198 , obo:CIDO_0000285 , obo:GO_0046718 . obo:VO_0005197 a rdfs:Class ; rdfs:label "SKYCovione"@en ; rdfs:comment "A SARS-CoV-2 protein subunit vaccine manufactured by SK Bioscience Co., Ltd., and equipped with an aluminum hydroxide adjuvant" ; rdfs:subClassOf obo:VO_0005269 . obo:VO_0000529 a rdf:Property ; rdfs:label "has vaccine adjuvant" ; rdfs:comment "a type of 'has vaccine component' relation that is specifically for vaccine adjuvant component" ; rdfs:domain obo:VO_0000001 ; rdfs:range ; rdfs:subPropertyOf obo:VO_0000520 . obo:OPMI_0000585 a rdfs:Class ; rdfs:label "payer plan period"@en ; rdfs:comment "A period time of the payment that is covered by a payer plan for a person." ; rdfs:subClassOf obo:OPMI_0000584 . obo:VO_0005393 a rdfs:Class ; rdfs:label "Almansour-001"@en ; rdfs:comment "A SARS-CoV-2 DNA vaccine developed by Imam Abdulrahman Bin Faisal University." ; rdfs:subClassOf obo:VO_0005203 . obo:VO_0005348 a rdfs:Class ; rdfs:label "LYB001"@en ; rdfs:comment "A COVID-19 virus-like particle vaccine developed by Yantai Patronus Biotech Co., Ltd." ; rdfs:subClassOf obo:VO_0005205 . a rdfs:Class ; rdfs:label "Progestational Hormone Receptor Agonists [MoA]" ; rdfs:subClassOf . obo:NCBITaxon_511432 a rdfs:Class ; rdfs:label "SARS coronavirus BJ182a" ; rdfs:subClassOf obo:NCBITaxon_694009 . obo:PATO_0001546 a rdfs:Class ; rdfs:label "quality of a solid" ; rdfs:comment "A physical quality inhering in a bearer by virtue of the bearer's exhibiting the physical characteristics of an entity characterized by particles arranged such that their shape and volume are relatively stable." ; rdfs:subClassOf obo:PATO_0002198 . obo:NCBITaxon_1508227 a rdfs:Class ; rdfs:label "Bat SARS-like coronavirus" ; rdfs:subClassOf obo:NCBITaxon_694009 . obo:CHEBI_48154 a rdfs:Class ; rdfs:label "sulfur oxide" ; rdfs:subClassOf obo:CHEBI_24836 , obo:CHEBI_26835 . obo:CIDO_0020235 a rdfs:Class ; rdfs:label "Phosphorus COVID-19 RT-qPCR Test" ; rdfs:seeAlso ; rdfs:subClassOf obo:CIDO_0000454 . a rdfs:Class ; rdfs:label "Macular Degeneration [Disease/Finding]" ; rdfs:subClassOf . obo:PR_000011650 a rdfs:Class ; rdfs:label "sigma non-opioid intracellular receptor 1" ; rdfs:comment "A protein that is a translation product of the human SIGMAR1 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:CHEBI_35716 a rdfs:Class ; rdfs:label "C-nitro compound" ; rdfs:comment "A nitro compound having the nitro group (-NO2) attached to a carbon atom." ; rdfs:subClassOf obo:CHEBI_35715 , obo:CHEBI_72695 . obo:PR_000007565 a rdfs:Class ; rdfs:label "vascular endothelial growth factor receptor 3" ; rdfs:comment "A vascular endothelial growth factor receptor that is a translation product of the human FLT4 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000001971 . obo:HP_0002086 a rdfs:Class ; rdfs:label "Abnormality of the respiratory system" ; rdfs:comment "An abnormality of the respiratory system, which include the airways, lungs, and the respiratory muscles." ; rdfs:subClassOf obo:HP_0000118 . a rdfs:Class ; rdfs:label "Blood Coagulation Disorders [Disease/Finding]" ; rdfs:subClassOf . obo:GO_0036120 a rdfs:Class ; rdfs:label "cellular response to platelet-derived growth factor stimulus" ; rdfs:comment "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a platelet-derived growth factor stimulus." ; rdfs:subClassOf obo:GO_0036119 , obo:GO_0071363 , obo:GO_0071495 . obo:CIDO_0000534 a rdfs:Class ; rdfs:label "NIAFNVVKKGCFTGV" ; rdfs:comment "A coronavirus epitope that is part of some S protein from HCoV NL63 composed of the following amino acids NIAFNVVKKGCFTGV" ; rdfs:subClassOf obo:CIDO_0000449 . obo:PR_P18510 a rdfs:Class ; rdfs:label "interleukin-1 receptor antagonist protein (human)" ; rdfs:comment "An interleukin-1 receptor antagonist protein that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000001137 , obo:PR_000029067 . obo:NCBITaxon_931915 a rdfs:Class ; rdfs:label "Alphacoronavirus Eptesicus fuscus/Appalachian Ridge/P1-C149/IT/USA/2009" ; rdfs:subClassOf obo:NCBITaxon_366617 . obo:VO_0000609 a rdfs:Class ; rdfs:label "viral vaccine" ; rdfs:comment "A vaccine that targets against a viral disease." ; rdfs:subClassOf obo:VO_0000001 . obo:NCBITaxon_1788478 a rdfs:Class ; rdfs:label "Miniopterus bat coronavirus BtCoV/4040" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:CHEBI_76617 a rdfs:Class ; rdfs:label "EC 2.7.10.2 (non-specific protein-tyrosine kinase) inhibitor" ; rdfs:comment "An EC 2.7.10.* (protein-tyrosine kinase) inhibitor that specifically blocks the action of non-specific protein-tyrosine kinase (EC 2.7.10.2)." ; rdfs:subClassOf obo:CHEBI_38637 , obo:CHEBI_76817 . obo:PR_000010419 a rdfs:Class ; rdfs:label "mirror-image polydactyly gene 1 protein" ; rdfs:comment "A protein that is a translation product of the human MIPOL1 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:PR_000004480 a rdfs:Class ; rdfs:label "V-type proton ATPase catalytic subunit A" ; rdfs:comment "A protein that is a translation product of the human ATP6V1A gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:CHEBI_76796 a rdfs:Class ; rdfs:label "EC 3.4.22.* (cysteine endopeptidase) inhibitor" ; rdfs:comment "An EC 3.4.* (hydrolases acting on peptide bond) inhibitor that interferes with the action of any cysteine endopeptidase (EC 3.4.22.*)." ; rdfs:subClassOf obo:CHEBI_60258 . obo:NCBITaxon_2691589 a rdfs:Class ; rdfs:label "Tylonycteris pachypus bat coronavirus HKU4-related" ; rdfs:subClassOf obo:NCBITaxon_2664183 . a rdfs:Class ; rdfs:label "Striated Muscle Metabolic Alteration [PE]" ; rdfs:subClassOf . obo:NCBITaxon_384345 a rdfs:Class ; rdfs:label "Human coronavirus NO/0023/05" ; rdfs:subClassOf obo:NCBITaxon_384335 . obo:CIDO_0000089 a rdfs:Class ; rdfs:label "SARS-CoV-2 replication inside cell"@en ; rdfs:comment "A coronavirus-host interaction by which the SARS-CoV-2 virus replicates inside the host cell" ; rdfs:subClassOf obo:CIDO_0000086 , obo:CIDO_0000197 , obo:CIDO_0000286 . obo:RO_0002233 a rdf:Property ; rdfs:label "has input"@en ; rdfs:comment "p has input c iff: p is a process, c is a material entity, c is a participant in p, c is present at the start of p, and the state of c is modified during p." ; rdfs:range . obo:PR_Q13617 a rdfs:Class ; rdfs:label "cullin-2 (human)" ; rdfs:comment "A cullin-2 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000006047 , obo:PR_000029067 . obo:GO_0045785 a rdfs:Class ; rdfs:label "positive regulation of cell adhesion" ; rdfs:comment "Any process that activates or increases the frequency, rate or extent of cell adhesion." ; rdfs:subClassOf obo:GO_0030155 , obo:GO_0048522 . obo:NCBITaxon_1076423 a rdfs:Class ; rdfs:label "Alphacoronavirus M.myo/I/Spain/2007" ; rdfs:subClassOf obo:NCBITaxon_366617 . obo:CL_0000558 a rdfs:Class ; rdfs:label "reticulocyte" ; rdfs:comment "An immature erythrocyte that changes the protein composition of its plasma membrane by exosome formation and extrusion. The types of protein removed differ between species though removal of the transferrin receptor is apparent in mammals and birds." ; rdfs:subClassOf obo:CL_0000000 . obo:CHEBI_78606 a rdfs:Class ; rdfs:label "Hsp70 inducer" ; rdfs:comment "Any inducer of heat shock protein 70." ; rdfs:subClassOf obo:CHEBI_35224 , obo:CHEBI_52206 . obo:NCBITaxon_1679911 a rdfs:Class ; rdfs:label "Coronavirus RCoV/Lmg115/Sig_spec/MEX/2011" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:CHEBI_93829 a rdfs:Class ; rdfs:label "4-[1-hydroxy-2-[4-(phenylmethyl)-1-piperidinyl]propyl]phenol" ; rdfs:subClassOf obo:CHEBI_26151 . obo:CHEBI_37808 a rdfs:Class ; rdfs:label "butane" ; rdfs:comment "A straight chain alkane composed of 4 carbon atoms." ; rdfs:subClassOf obo:CHEBI_138675 , obo:CHEBI_18310 . obo:PR_P49840 a rdfs:Class ; rdfs:label "glycogen synthase kinase-3 alpha (human)" ; rdfs:comment "A glycogen synthase kinase-3 alpha that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000008287 , obo:PR_000029067 . obo:CHEBI_32600 a rdfs:Class ; rdfs:label "tetracene" ; rdfs:comment "An acene that consists of four ortho-fused benzene rings in a rectilinear arrangement." ; rdfs:subClassOf obo:CHEBI_35297 , obo:CHEBI_51270 . a rdfs:Class ; rdfs:label "N [Preparations]" ; rdfs:subClassOf . obo:OPMI_0000539 a rdfs:Class ; rdfs:label "postoperative diagnosis status"@en ; rdfs:comment "A postoperative diagnosis is a diagnosis or diagnoses discovered or confirmed during the surgery. Often it is the same as the preoperative diagnosis." ; rdfs:subClassOf obo:OPMI_0000533 . obo:CIDO_0020050 a rdfs:Class ; rdfs:label "BioCheck SARS-CoV-2 IgM Antibody Test Kit" ; rdfs:seeAlso ; rdfs:subClassOf obo:CIDO_0000454 . obo:NCBITaxon_11134 a rdfs:Class ; rdfs:label "Bovine coronavirus strain vaccine" ; rdfs:subClassOf obo:NCBITaxon_11128 . obo:PR_P13861 a rdfs:Class ; rdfs:label "cAMP-dependent protein kinase type II-alpha regulatory subunit (human)" ; rdfs:comment "A cAMP-dependent protein kinase type II-alpha regulatory subunit that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000013230 , obo:PR_000029067 . a rdfs:Class ; rdfs:label "Nervous System Diseases [Disease/Finding]" ; rdfs:subClassOf . obo:OBCS_0000220 a rdfs:Class ; rdfs:label "derived data from inferential statistical analysis"@en ; rdfs:comment "A data item that is derived from an inferential statistical data analysis." ; rdfs:subClassOf obo:IAO_0000027 , obo:OBCS_0000218 . obo:CHEBI_23247 a rdfs:Class ; rdfs:label "cinnamamides" ; rdfs:comment "An enamide which is cinnamamide or a derivative of cinnamamide obtained by replacement of one or more of its hydrogens." ; rdfs:subClassOf obo:CHEBI_51751 . obo:CHEBI_76832 a rdfs:Class ; rdfs:label "EC 4.3.1.* (ammonia-lyase) inhibitor" ; rdfs:comment "An EC 4.3.* (C-N lyase) inhibitor that interferes with the action of any ammonia-lyase (EC 4.3.1.*)." ; rdfs:subClassOf obo:CHEBI_76713 . obo:CHEBI_6888 a rdfs:Class ; rdfs:label "Methylprednisolone" ; rdfs:comment "A 6-methylprednisolone that has formula C22H30O5." ; rdfs:subClassOf obo:CHEBI_139590 , obo:CHEBI_139592 , obo:CHEBI_50366 . obo:CHEBI_68495 a rdfs:Class ; rdfs:label "apoptosis inducer" ; rdfs:comment "Any substance that induces the process of apoptosis (programmed cell death) in multi-celled organisms." ; rdfs:subClassOf obo:CHEBI_52206 . obo:PR_000002001 a rdfs:Class ; rdfs:label "receptor-type tyrosine-protein kinase FLT3" ; rdfs:comment "A CSF-1/PDGF receptor-type tyrosine-protein kinase that is a translation product of the human FLT3 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000001810 . obo:CHEBI_23134 a rdfs:Class ; rdfs:label "chlorobenzoic acid" ; rdfs:comment "Any member of the class of benzoic acids in which the benzene ring is substituted by at least one chloro group." ; rdfs:subClassOf obo:CHEBI_22723 , obo:CHEBI_36685 . obo:HP_0001977 a rdfs:Class ; rdfs:label "Abnormal thrombosis" ; rdfs:comment "Venous or arterial thrombosis (formation of blood clots) of spontaneous nature and which cannot be fully explained by acquired risk (e.g. atherosclerosis)." ; rdfs:subClassOf obo:HP_0001871 . obo:CIDO_0000474 a rdfs:Class ; rdfs:label "ASGVFGVNLRTNFTI" ; rdfs:comment "A coronavirus epitope that is part of some S protein from HCoV NL63 composed of the following amino acids ASGVFGVNLRTNFTI" ; rdfs:subClassOf obo:CIDO_0000449 . obo:CIDO_0000026 a rdfs:Class ; rdfs:label "COVID-19 diagnostic process by viral culture and isolation"@en ; rdfs:comment "A COVID-19 diagnostic process by viral culturing in cells and identification of the isolated viruses" ; rdfs:subClassOf obo:CIDO_0000424 . obo:CHEBI_76741 a rdfs:Class ; rdfs:label "EC 1.14.* (oxidoreductase acting on paired donors, with incorporation or reduction of molecular oxygen) inhibitor" ; rdfs:comment "An oxidoreductase inhibitor which interferes with the action of an oxidoreductase acting on hydrogen as donors (EC 1.14.*.*)." ; rdfs:subClassOf obo:CHEBI_76725 . obo:DOID_1470 a rdfs:Class ; rdfs:label "major depressive disorder" ; rdfs:comment "An endogenous depression that is characterized by an all-encompassing low mood accompanied by low self-esteem, and by loss of interest or pleasure in normally enjoyable activities." ; rdfs:subClassOf obo:DOID_1596 . obo:VO_0005146 a rdfs:Class ; rdfs:label "VRC-SRSDNA015-00-VP vaccine" ; rdfs:comment "A SARS DNA vaccine made of a single closed plasmid DNA marcromolecule (VRC-8138) that produces a deletion mutant of the SARS Spike glycoprotein" ; rdfs:subClassOf obo:VO_0012183 . obo:PR_Q08379 a rdfs:Class ; rdfs:label "golgin subfamily A member 2 (human)" ; rdfs:comment "A golgin subfamily A member 2 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000008131 , obo:PR_000029067 . obo:PR_000012438 a rdfs:Class ; rdfs:label "proprotein convertase subtilisin/kexin type 6" ; rdfs:comment "A subtilisin/kexin-type proprotein convertase that is a translation product of the human PCSK6 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000003136 . obo:NCBITaxon_1643896 a rdfs:Class ; rdfs:label "Bat coronavirus BEM001F" ; rdfs:subClassOf obo:NCBITaxon_696098 . obo:PR_000014891 a rdfs:Class ; rdfs:label "NAD-dependent deacetylase sirtuin-5" ; rdfs:comment "A protein that is a translation product of the human SIRT5 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:CHEBI_9544 a rdfs:Class ; rdfs:label "thiethylperazine" ; rdfs:comment "A member of the class of phenothiazines that is perazine substituted by a ethylsulfanyl group at position 2." ; rdfs:subClassOf obo:CHEBI_38093 , obo:CHEBI_46920 . obo:NCBITaxon_2778965 a rdfs:Class ; rdfs:label "Erinaceus amurensis coronavirus" ; rdfs:subClassOf obo:NCBITaxon_1986197 . obo:CHEBI_32786 a rdfs:Class ; rdfs:label "tyrosinium" ; rdfs:comment "An alpha-amino-acid cation that is the conjugate acid of tyrosine, arising from protonation of the amino group." ; rdfs:subClassOf obo:CHEBI_33719 . obo:PR_P16591 a rdfs:Class ; rdfs:label "tyrosine-protein kinase Fer (human)" ; rdfs:comment "A tyrosine-protein kinase Fer that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000007458 , obo:PR_000029067 . obo:CHEBI_91796 a rdfs:Class ; rdfs:label "9-[3-(3,5-dimethyl-1-piperazinyl)propyl]carbazole" ; rdfs:subClassOf obo:CHEBI_48513 . obo:CHEBI_32507 a rdfs:Class ; rdfs:label "glycinium" ; rdfs:comment "An alpha-amino-acid cation that is the conjugate acid of glycine, arising from protonation of the amino." ; rdfs:subClassOf obo:CHEBI_33719 . obo:VO_0000728 a rdfs:Class ; rdfs:label "RNA vaccine role"@en ; rdfs:comment "a vaccine role that indicates the vaccine being a RNA vaccine. " ; rdfs:subClassOf obo:VO_0000615 . obo:OPMI_0000579 a rdfs:Class ; rdfs:label "measurement time"@en ; rdfs:comment "A time when a measurement is conducted." ; rdfs:subClassOf obo:BFO_0000148 . obo:OAE_0004578 a rdfs:Class ; rdfs:label "Level 3 TTS AE"@en ; rdfs:comment "A possible case TTS" ; rdfs:subClassOf obo:OAE_0004540 . obo:CIDO_0020242 a rdfs:Class ; rdfs:label "Procleix SARS-CoV-2 Assay" ; rdfs:seeAlso ; rdfs:subClassOf obo:CIDO_0000454 . obo:CHEBI_121256 a rdfs:Class ; rdfs:label "2-amino-7-methyl-5-oxo-4-(2,4,5-trimethoxyphenyl)-4,6,7,8-tetrahydro-1-benzopyran-3-carbonitrile" ; rdfs:subClassOf obo:CHEBI_51683 . obo:GO_0042053 a rdfs:Class ; rdfs:label "regulation of dopamine metabolic process" ; rdfs:comment "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving dopamine." ; rdfs:subClassOf obo:GO_0042069 . obo:NCBITaxon_497931 a rdfs:Class ; rdfs:label "Bat coronavirus M.das/Germany/D3.4/2007" ; rdfs:subClassOf obo:NCBITaxon_366617 . obo:CHEBI_50698 a rdfs:Class ; rdfs:label "pyrimidine N-oxide" ; rdfs:subClassOf obo:CHEBI_35580 , obo:CHEBI_39447 . a rdfs:Class ; rdfs:label "Anxiety Disorders [Disease/Finding]" ; rdfs:subClassOf . obo:CHEBI_36587 a rdfs:Class ; rdfs:label "organic oxo compound" ; rdfs:comment "Organic compounds containing an oxygen atom, =O, doubly bonded to carbon or another element." ; rdfs:subClassOf obo:CHEBI_50860 , obo:CHEBI_72695 . obo:PR_P51957 a rdfs:Class ; rdfs:label "serine/threonine-protein kinase Nek4 (human)" ; rdfs:comment "A serine/threonine-protein kinase Nek4 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000011130 , obo:PR_000029067 . obo:CHEBI_52208 a rdfs:Class ; rdfs:label "biophysical role" ; rdfs:subClassOf obo:CHEBI_24432 . obo:CIDO_0000034 a rdfs:Class ; rdfs:label "COVID-19 diagnostic process by chest radiography"@en ; rdfs:comment "COVID-19 diagnostic process by thoracic imaging" ; rdfs:subClassOf obo:CIDO_0000033 . obo:DOID_0070082 a rdfs:Class ; rdfs:label "schizophrenia 6" ; rdfs:comment "A schizophrenia that has_material_basis_in an autosomal dominant mutation of SCZD6 on chromosome 8p21." ; rdfs:subClassOf obo:DOID_0050736 , obo:DOID_5419 . obo:CIDO_0020079 a rdfs:Class ; rdfs:label "Clinomics TrioDx RT-PCR COVID-19 Test" ; rdfs:seeAlso ; rdfs:subClassOf obo:CIDO_0000454 . obo:CHEBI_29348 a rdfs:Class ; rdfs:label "fatty amide" ; rdfs:comment "A monocarboxylic acid amide derived from a fatty acid." ; rdfs:subClassOf obo:CHEBI_29347 , obo:CHEBI_61697 . obo:GO_0002694 a rdfs:Class ; rdfs:label "regulation of leukocyte activation" ; rdfs:comment "Any process that modulates the frequency, rate, or extent of leukocyte activation." ; rdfs:subClassOf obo:GO_0002682 , obo:GO_0050865 . obo:GO_0048869 a rdfs:Class ; rdfs:label "cellular developmental process" ; rdfs:comment "A biological process whose specific outcome is the progression of a cell over time from an initial condition to a later condition." ; rdfs:subClassOf obo:GO_0009987 , obo:GO_0032502 . obo:NCBITaxon_702733 a rdfs:Class ; rdfs:label "Bat coronavirus Philippines/Diliman1552G1/2008" ; rdfs:subClassOf obo:NCBITaxon_366617 . obo:CIDO_0020225 a rdfs:Class ; rdfs:label "Orawell IgM/IgG Rapid Test" ; rdfs:subClassOf obo:CIDO_0000454 . obo:CHEBI_82981 a rdfs:Class ; rdfs:label "(2S,4R)-terconazole" ; rdfs:comment "A 1-(4-{[2-(2,4-dichlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy}phenyl)-4-isopropylpiperazine in which positions 2 and 4 of the 1,3-dioxolane moiety have S and R configuration, respectively." ; rdfs:subClassOf obo:CHEBI_82979 . obo:PR_000014021 a rdfs:Class ; rdfs:label "serine/threonine-protein kinase RIO3" ; rdfs:comment "A protein that is a translation product of the human RIOK3 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . a rdfs:Class ; rdfs:label "Negative Chronotropy [PE]" ; rdfs:subClassOf . obo:CIDO_0020209 a rdfs:Class ; rdfs:label "NEcov19 RT-PCR Assay" ; rdfs:seeAlso ; rdfs:subClassOf obo:CIDO_0000454 . obo:OBI_0002505 a rdfs:Class ; rdfs:label "milk specimen" ; rdfs:comment "A specimen that is derived from milk." ; rdfs:subClassOf obo:OBI_2000009 . obo:NCBITaxon_931904 a rdfs:Class ; rdfs:label "Alphacoronavirus Eptesicus fuscus/Appalachian Ridge/P1-C362/IT/USA/2009" ; rdfs:subClassOf obo:NCBITaxon_366617 . obo:CHEBI_76414 a rdfs:Class ; rdfs:label "propellant" ; rdfs:comment "A compressed gas or liquid with a boiling point lower than room temperature which to used to propel and dispense liquids such as deodorants, insecticides, paints, etc. from aerosol cans." ; rdfs:subClassOf obo:CHEBI_33232 . obo:CHEBI_35441 a rdfs:Class ; rdfs:label "antiinfective agent" ; rdfs:comment "A substance used in the prophylaxis or therapy of infectious diseases." ; rdfs:subClassOf obo:CHEBI_23888 . a rdfs:Class ; rdfs:label "Pyrimidines [Chemical/Ingredient]" ; rdfs:subClassOf . a rdfs:Class ; rdfs:label "Respiratory Tract Infections [Disease/Finding]" ; rdfs:subClassOf , . obo:NCBITaxon_1415832 a rdfs:Class ; rdfs:label "Bat SARS-like coronavirus Rs3267-1" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:OPMI_0000574 a rdfs:Class ; rdfs:label "days of drug supply"@en ; rdfs:comment "This days of the supply of a drug that is given on the prescription." ; rdfs:subClassOf obo:IAO_0000109 . obo:PR_P12931 a rdfs:Class ; rdfs:label "proto-oncogene tyrosine-protein kinase Src (human)" ; rdfs:comment "A proto-oncogene tyrosine-protein kinase Src that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000027234 , obo:PR_000029067 . obo:UBERON_0002046 a rdfs:Class ; rdfs:label "thyroid gland" ; rdfs:comment "A two-lobed endocrine gland found in all vertebrates, located in front of and on either side of the trachea in humans, and producing various hormones, such as triiodothyronine and calcitonin[BTO]." ; rdfs:subClassOf obo:UBERON_0000465 . obo:PR_Q92900 a rdfs:Class ; rdfs:label "regulator of nonsense transcripts 1 (human)" ; rdfs:comment "A regulator of nonsense transcripts 1 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000017108 , obo:PR_000029067 . a rdfs:Class ; rdfs:label "Oligomycins [Chemical/Ingredient]" ; rdfs:subClassOf . obo:PR_000007957 a rdfs:Class ; rdfs:label "gamma-glutamyl hydrolase" ; rdfs:comment "A protein that is a translation product of the human GGH gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:NCBITaxon_1264898 a rdfs:Class ; rdfs:label "Ferret coronavirus" ; rdfs:subClassOf obo:NCBITaxon_2509496 . obo:OGG_3000003576 a rdfs:Class ; rdfs:label "IL8" ; rdfs:comment "Other designations: T-cell chemotactic factor|alveolar macrophage chemotactic factor I|beta endothelial cell-derived neutrophil activating peptide|beta-thromboglobulin-like protein|chemokine (C-X-C motif) ligand 8|emoctakin|granulocyte chemotactic protein 1|interleukin-8|lung giant cell carcinoma-derived chemotactic protein|lymphocyte derived neutrophil activating peptide|monocyte-derived neutrophil chemotactic factor|monocyte-derived neutrophil-activating peptide|neutrophil-activating peptide 1|small inducible cytokine subfamily B, member 8|tumor necrosis factor-induced gene 1" ; rdfs:subClassOf obo:OGG_2060009606 . obo:CHEBI_2981 a rdfs:Class ; rdfs:label "baicalin" ; rdfs:comment "The glycosyloxyflavone which is the 7-O-glucuronide of baicalein. It is an active ingredient of Chinese herbal medicine Scutellaria baicalensis." ; rdfs:subClassOf obo:CHEBI_24302 , obo:CHEBI_38686 , obo:CHEBI_50018 , obo:CHEBI_63367 . obo:BFO_0000006 a rdfs:Class ; rdfs:label "spatial region"@en ; rdfs:subClassOf obo:BFO_0000141 . obo:BFO_0000123 a rdf:Property ; rdfs:label "has spatial occupant at some time"@en ; rdfs:domain obo:BFO_0000006 ; rdfs:range obo:BFO_0000004 . obo:BFO_0000152 a rdf:Property ; rdfs:label "spatial projection of spatiotemporal at some time"@en ; rdfs:domain obo:BFO_0000006 ; rdfs:range obo:BFO_0000011 . obo:CHEBI_29995 a rdfs:Class ; rdfs:label "aspartate(2-)" ; rdfs:comment "A C4-dicarboxylate that is the dianion obtained by the deprotonation of both the carboxy groups of aspartic acid." ; rdfs:subClassOf obo:CHEBI_132943 , obo:CHEBI_61336 . obo:CIDO_0000618 a rdfs:Class ; rdfs:label "V144- in SARS-CoV-2 S protein"@en ; rdfs:comment "An AA mutation or AA variant that has mutated an amino acid at position 144 in S protein into a deletion." ; rdfs:subClassOf obo:CIDO_0001144 . obo:CIDO_0000609 a rdf:Property ; rdfs:label "is AA mutation of"@en ; rdfs:range . obo:GO_0048523 a rdfs:Class ; rdfs:label "negative regulation of cellular process" ; rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level." ; rdfs:subClassOf obo:GO_0048519 , obo:GO_0050794 . obo:NCBITaxon_1699335 a rdfs:Class ; rdfs:label "Myotis Bat Alphacoronavirus strain YNXY_39C" ; rdfs:subClassOf obo:NCBITaxon_366617 . obo:OPMI_0000528 a rdfs:Class ; rdfs:label "condition temporal region"@en ; rdfs:comment "the date or time on which a condition occurs" ; rdfs:subClassOf obo:BFO_0000148 . obo:PR_Q2TAA5 a rdfs:Class ; rdfs:label "GDP-Man:Man(3)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase (human)" ; rdfs:comment "A GDP-Man:Man(3)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000003939 , obo:PR_000029067 . obo:PR_P11229 a rdfs:Class ; rdfs:label "muscarinic acetylcholine receptor M1 (human)" ; rdfs:comment "A muscarinic acetylcholine receptor M1 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000001613 , obo:PR_000029067 . a rdfs:Class ; rdfs:label "Piperazines [Chemical/Ingredient]" ; rdfs:subClassOf . a rdfs:Class ; rdfs:label "Norepinephrine Uptake Inhibitors [MoA]" ; rdfs:subClassOf . obo:CIDO_0000377 a rdfs:Class ; rdfs:label "SARS-CoV-2 Gamma variant"@en ; rdfs:comment "Nextstrain clade 20J" ; rdfs:subClassOf obo:CIDO_0000407 . obo:NCBITaxon_312027 a rdfs:Class ; rdfs:label "SARS coronavirus WH20" ; rdfs:subClassOf obo:NCBITaxon_694009 . obo:OBI_1000049 a rdfs:Class ; rdfs:label "whole mount tissue"@en ; rdfs:comment "A whole organism preparation resulting from a histological preparation known as whole mount preparation where the whole specimen is mounted or spread on the microscope (glass) slide"@en ; rdfs:subClassOf obo:OBI_0000680 , obo:OBI_0000953 , obo:OBI_0001479 . a rdfs:Class ; rdfs:label "Nose Diseases [Disease/Finding]" ; rdfs:subClassOf , . obo:NCBITaxon_622709 a rdfs:Class ; rdfs:label "Bat coronavirus Hipposideros/GhanaKwam/10/2008" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:PR_000011397 a rdfs:Class ; rdfs:label "nuclear receptor subfamily 1 group I member 2" ; rdfs:comment "A protein that is a translation product of the human NR1I2 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:OBI_0000981 a rdfs:Class ; rdfs:label "agar stab specimen" ; rdfs:comment "a specimen that is output of a process that cell culture inoculated into agar for long term storage." ; rdfs:subClassOf obo:OBI_0001472 . obo:HP_0100786 a rdfs:Class ; rdfs:label "Hypersomnia" ; rdfs:subClassOf obo:HP_0002360 . obo:NCBITaxon_421444 a rdfs:Class ; rdfs:label "SARS coronavirus TJ01" ; rdfs:subClassOf obo:NCBITaxon_694009 . obo:PR_000013422 a rdfs:Class ; rdfs:label "prostaglandin E synthase 2" ; rdfs:comment "A protein that is a translation product of the human PTGES2 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:CIDO_0000582 a rdfs:Class ; rdfs:label "SARS-CoV-2 Nsp8 protein interaction with host protein"@en ; rdfs:comment "A molecular interaction that has participant of the SARS-CoV-2 Nsp8 protein and a host protein" ; rdfs:subClassOf obo:CIDO_0000348 . obo:PR_000031521 a rdfs:Class ; rdfs:label "growth hormone-inducible transmembrane protein" ; rdfs:comment "A protein that is a translation product of the human GHITM gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:NCBITaxon_441982 a rdfs:Class ; rdfs:label "Masked palm civet coronavirus Guangxi/D728/2005" ; rdfs:subClassOf obo:NCBITaxon_441985 . obo:CHEBI_74518 a rdfs:Class ; rdfs:label "anti-obesity agent" ; rdfs:comment "Any substance which is used to reduce or control weight." ; rdfs:subClassOf obo:CHEBI_52210 . obo:CHEBI_73690 a rdfs:Class ; rdfs:label "erythrose 4-phosphate/phosphoenolpyruvate family amino acid" ; rdfs:comment "An L-alpha-amino acid which is biosynthesised from erythrose 4-phosphate and phosphoenolpyruvate (i.e. phenylalanine, tyrosine, and tryptophan). A closed class." ; rdfs:subClassOf obo:CHEBI_15705 , obo:CHEBI_83813 . obo:CHEBI_25512 a rdfs:Class ; rdfs:label "neurotransmitter" ; rdfs:comment "An endogenous compound that is used to transmit information across the synapse between a neuron and another cell." ; rdfs:subClassOf obo:CHEBI_33280 . obo:NCBITaxon_903616 a rdfs:Class ; rdfs:label "Kenya bat coronavirus BtKY78" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:NCBITaxon_681876 a rdfs:Class ; rdfs:label "Kenya bat coronavirus BtKY31" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:HP_0001716 a rdfs:Class ; rdfs:label "Wolff-Parkinson-White syndrome" ; rdfs:comment "A disorder of the cardiac conduction system of the heart characterized by ventricular preexcitation due to the presence of an abnormal accessory atrioventricular electrical conduction pathway." ; rdfs:subClassOf obo:HP_0004309 . obo:CHEBI_83575 a rdfs:Class ; rdfs:label "monofluorobenzenes" ; rdfs:comment "Any member of the class of fluorobenzenes containing a mono- or poly-substituted benzene ring carrying a single fluorine substitutent." ; rdfs:subClassOf obo:CHEBI_35496 . obo:HP_0011697 a rdfs:Class ; rdfs:label "Supraventricular tachycardia with a manifest accessory pathway on the right free wall" ; rdfs:subClassOf obo:HP_0011694 . obo:NCBITaxon_1400795 a rdfs:Class ; rdfs:label "Bat coronavirus Costa Rica" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:CIDO_0000759 a rdfs:Class ; rdfs:label "SARS-CoV2 M protein binding to human INTS4" ; rdfs:comment "SARS-CoV2 M protein binding to human INTS4, as evidented by an affinity-purification mass spectrometry experiment" ; rdfs:subClassOf obo:CIDO_0000055 . a rdfs:Class ; rdfs:label "HYDROXYPROGESTERONE CAPROATE" ; rdfs:subClassOf . obo:CIDO_0000822 a rdfs:Class ; rdfs:label "SARS-CoV2 nsp12 protein binding to human ZNF318" ; rdfs:comment "SARS-CoV2 nsp12 protein binding to human ZNF318, as evidented by an affinity-purification mass spectrometry experiment" ; rdfs:subClassOf obo:CIDO_0000057 . obo:UBERON_0000178 a rdfs:Class ; rdfs:label "blood" ; rdfs:comment "A fluid that is composed of blood plasma and erythrocytes." ; rdfs:subClassOf obo:UBERON_0006314 . obo:NCBITaxon_1465644 a rdfs:Class ; rdfs:label "Deltacoronavirus PDCoV/USA/Illinois121/2014" ; rdfs:subClassOf obo:NCBITaxon_1159905 . obo:CIDO_0000502 a rdfs:Class ; rdfs:label "SAMHSLLFGMLRRLD" ; rdfs:comment "A coronavirus epitope that is part of some S protein from HCoV NL63 composed of the following amino acids SAMHSLLFGMLRRLD" ; rdfs:subClassOf obo:CIDO_0000449 . obo:CHEBI_39745 a rdfs:Class ; rdfs:label "dihydrogenphosphate" ; rdfs:comment "A monovalent inorganic anion that consists of phosphoric acid in which one of the three OH groups has been deprotonated." ; rdfs:subClassOf obo:CHEBI_35780 , obo:CHEBI_79389 . obo:NCBITaxon_229993 a rdfs:Class ; rdfs:label "SARS coronavirus TW1" ; rdfs:subClassOf obo:NCBITaxon_694009 . obo:OBI_0002533 a rdfs:Class ; rdfs:label "colon specimen" ; rdfs:comment "A specimen that is derived from colon." ; rdfs:subClassOf obo:OBI_0001479 . obo:PR_000008139 a rdfs:Class ; rdfs:label "golgin subfamily B member 1" ; rdfs:comment "A protein that is a translation product of the human GOLGB1 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:CHEBI_35703 a rdfs:Class ; rdfs:label "xenobiotic" ; rdfs:comment "A xenobiotic (Greek, xenos \"foreign\"; bios \"life\") is a compound that is foreign to a living organism. Principal xenobiotics include: drugs, carcinogens and various compounds that have been introduced into the environment by artificial means." ; rdfs:subClassOf obo:CHEBI_24432 . obo:PR_Q9UM07 a rdfs:Class ; rdfs:label "protein-arginine deiminase type-4 (human)" ; rdfs:comment "A protein-arginine deiminase type-4 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000012222 , obo:PR_000029067 . obo:CIDO_0000102 a rdfs:Class ; rdfs:label "interruption to coronavirus cell invasion"@en ; rdfs:comment "A process that interrupts coronavirus entry to host cell" ; rdfs:subClassOf obo:CIDO_0000098 . obo:OBI_0666667 a rdfs:Class ; rdfs:label "nucleic acid extraction"@en ; rdfs:comment "a material separation to recover the nucleic acid fraction of an input material"@en ; rdfs:subClassOf obo:OBI_0302884 . obo:CHEBI_76989 a rdfs:Class ; rdfs:label "phytoestrogen" ; rdfs:comment "Any compound produced by a plant that happens to have estrogenic activity." ; rdfs:subClassOf obo:CHEBI_50114 . obo:NCBITaxon_2794216 a rdfs:Class ; rdfs:label "Pecari tajacu coronavirus" ; rdfs:subClassOf obo:NCBITaxon_696098 . obo:NCBITaxon_1644145 a rdfs:Class ; rdfs:label "Bat coronavirus MAH058F" ; rdfs:subClassOf obo:NCBITaxon_696098 . obo:UBERON_0001729 a rdfs:Class ; rdfs:label "oropharynx" ; rdfs:comment "the portion of the pharynx that lies between the soft palate and the upper edge of the epiglottis" ; rdfs:subClassOf obo:UBERON_0000465 . a rdfs:Class ; rdfs:label "Carcinoma, Hepatocellular [Disease/Finding]" ; rdfs:subClassOf , . obo:NCBITaxon_389140 a rdfs:Class ; rdfs:label "Bat coronavirus (BtCoV/A629/2005)" ; rdfs:subClassOf obo:NCBITaxon_389126 . obo:NCBITaxon_429331 a rdfs:Class ; rdfs:label "Murine coronavirus repA59/RJHM" ; rdfs:subClassOf obo:NCBITaxon_11138 . obo:PR_Q9UNX3 a rdfs:Class ; rdfs:label "60S ribosomal protein L26-like 1 (human)" ; rdfs:comment "A 60S ribosomal protein L26-like 1 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000014207 , obo:PR_000029067 . obo:PR_Q16602 a rdfs:Class ; rdfs:label "calcitonin gene-related peptide type 1 receptor (human)" ; rdfs:comment "A calcitonin gene-related peptide type 1 receptor that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000004973 , obo:PR_000029067 . obo:HP_0011700 a rdfs:Class ; rdfs:label "Automatic atrial tachycardia" ; rdfs:comment "Chronic supraventricular tachycardia predominantly seen in childhood." ; rdfs:subClassOf obo:HP_0001692 . obo:NCBITaxon_1146848 a rdfs:Class ; rdfs:label "Bat coronavirus M.daubentonii/UK/Wyt/964Co" ; rdfs:subClassOf obo:NCBITaxon_366617 . obo:CHEBI_62488 a rdfs:Class ; rdfs:label "signalling molecule" ; rdfs:comment "A molecular messenger in which the molecule is specifically involved in transmitting information between cells. Such molecules are released from the cell sending the signal, cross over the gap between cells by diffusion, and interact with specific receptors in another cell, triggering a response in that cell by activating a series of enzyme controlled reactions which lead to changes inside the cell." ; rdfs:subClassOf obo:CHEBI_33280 . obo:NCBITaxon_2509514 a rdfs:Class ; rdfs:label "Tegacovirus" ; rdfs:subClassOf obo:NCBITaxon_693996 . obo:PR_Q8TDR2 a rdfs:Class ; rdfs:label "serine/threonine-protein kinase 35 (human)" ; rdfs:comment "A serine/threonine-protein kinase 35 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000015752 , obo:PR_000029067 . obo:DOID_0050736 a rdfs:Class ; rdfs:label "autosomal dominant disease" ; rdfs:comment "An autosomal genetic disease that is characterized by the presence of one disease-associated mutation of a gene which is sufficient to cause the disease." ; rdfs:subClassOf obo:DOID_0050739 . obo:CIDO_0000290 a rdfs:Class ; rdfs:label "human infected with pathogen"@en ; rdfs:comment "A human that is infected with some pathogen" ; rdfs:subClassOf obo:NCBITaxon_9606 . obo:PR_000032038 a rdfs:Class ; rdfs:label "sigma intracellular receptor 2" ; rdfs:comment "A protein that is a translation product of the human TMEM97 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:PR_000008915 a rdfs:Class ; rdfs:label "interferon alpha-2" ; rdfs:comment "An interferon alpha that is a translation product of the human IFNA2 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000024938 . obo:CHEBI_48901 a rdfs:Class ; rdfs:label "thiazoles" ; rdfs:comment "An azole in which the five-membered heterocyclic aromatic skeleton contains a N atom and one S atom." ; rdfs:subClassOf obo:CHEBI_25693 , obo:CHEBI_38101 , obo:CHEBI_38106 , obo:CHEBI_38179 , obo:CHEBI_68452 . obo:PR_O15264 a rdfs:Class ; rdfs:label "mitogen-activated protein kinase 13 (human)" ; rdfs:comment "A mitogen-activated protein kinase 13 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000010154 , obo:PR_000029067 . obo:CHEBI_85010 a rdfs:Class ; rdfs:label "eltrombopag" ; rdfs:comment "A hydrazine in which each nitrogen atom is substituted, one by a 3'-carboxy-2-hydroxy[1,1'-biphenyl]-3-yl group and the other by a 1-(3,4-dimethylphenyl)-3-methyl-5-oxo-1,5-dihydro-4H-pyrazol-4-ylidene group. A small molecule agonist of the c-mpl (TpoR) receptor (the physiological target of the hormone thrombopoietin), it has been developed as a medication for conditions that lead to thrombocytopenia (abnormally low platelet counts)." ; rdfs:subClassOf obo:CHEBI_22723 , obo:CHEBI_24631 , obo:CHEBI_26410 . obo:CHEBI_35480 a rdfs:Class ; rdfs:label "analgesic" ; rdfs:comment "An agent capable of relieving pain without the loss of consciousness or without producing anaesthesia. In addition, analgesic is a role played by a compound which is exhibited by a capability to cause a reduction of pain symptoms." ; rdfs:subClassOf obo:CHEBI_23888 , obo:CHEBI_52210 . obo:NCBITaxon_393046 a rdfs:Class ; rdfs:label "Bat coronavirus HKU7" ; rdfs:subClassOf obo:NCBITaxon_366617 . obo:PR_000050019 a rdfs:Class ; rdfs:label "glycogen synthase kinase 3" ; rdfs:comment "A GSK3-like glycogen synthase kinase that is a translation product of the human GSK3A or GSK3B genes, 1:1 orthologs thereof, or a semi-ortholog thereof." ; rdfs:subClassOf obo:PR_000035899 . obo:CHEBI_51286 a rdfs:Class ; rdfs:label "tetracenequinones" ; rdfs:subClassOf obo:CHEBI_51285 , obo:CHEBI_51958 . a rdfs:Class ; rdfs:label "Intestinal Diseases, Parasitic [Disease/Finding]" ; rdfs:subClassOf , . obo:VO_0001358 a rdfs:Class ; rdfs:label "tensoactive compound vaccine adjuvant" ; rdfs:comment "a vaccine adjuvant that includes tensioactive material. Tensioactive materials, surfactants or active surface agents are chemical substances with a polar-non polar structure. These substances have a tendency to locate themselves at the surface creating an adsorbed monomolecular layer on the interface." ; rdfs:subClassOf obo:VO_0000580 . obo:GO_0071868 a rdfs:Class ; rdfs:label "cellular response to monoamine stimulus" ; rdfs:comment "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a monoamine stimulus. A monoamine is any of a group of molecular messengers that contain one amino group that is connected to an aromatic ring by ethylene group (-CH2-CH2-). Monoamines are derived from the aromatic amino acids phenylalanine, tyrosine, histidine and tryptophan." ; rdfs:subClassOf obo:GO_0071417 , obo:GO_0071867 . a rdfs:Class ; rdfs:label "Mycophenolic Acid [Chemical/Ingredient]" ; rdfs:subClassOf . obo:NCBITaxon_1679927 a rdfs:Class ; rdfs:label "Coronavirus Rabbit_CoV/La09_32/Ory_cun/ESP/2009" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:PR_Q15392 a rdfs:Class ; rdfs:label "Delta(24)-sterol reductase (human)" ; rdfs:comment "A Delta(24)-sterol reductase that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000006453 , obo:PR_000029067 . obo:CHEBI_16199 a rdfs:Class ; rdfs:label "urea" ; rdfs:comment "A carbonyl group with two C-bound amine groups. The commercially available fertilizer has an analysis of 46-0-0 (N-P2O5-K2O)." ; rdfs:subClassOf obo:CHEBI_29347 , obo:CHEBI_64708 . obo:CHEBI_38338 a rdfs:Class ; rdfs:label "aminopyrimidine" ; rdfs:comment "A member of the class of pyrimidines that is pyrimidine substituted by at least one amino group and its derivatives." ; rdfs:subClassOf obo:CHEBI_33860 , obo:CHEBI_39447 . obo:CIDO_0000799 a rdfs:Class ; rdfs:label "SARS-CoV2 nsp10 protein binding to human ERGIC1" ; rdfs:comment "SARS-CoV2 nsp10 protein binding to human ERGIC1, as evidented by an affinity-purification mass spectrometry experiment" ; rdfs:subClassOf obo:CIDO_0000064 . obo:CIDO_0000265 a rdfs:Class ; rdfs:label "CRISPR-based diagnostic assay for SARS-CoV-2"@en ; rdfs:subClassOf obo:CIDO_0000258 . obo:PR_000007215 a rdfs:Class ; rdfs:label "electron transfer flavoprotein subunit alpha, mitochondrial" ; rdfs:comment "A protein that is a translation product of the human ETFA gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . a rdfs:Class ; rdfs:label "Skin Diseases, Papulosquamous [Disease/Finding]" ; rdfs:subClassOf . obo:CIDO_0020072 a rdfs:Class ; rdfs:label "CentoFast-SARS-CoV-2 RT-PCR Assay" ; rdfs:seeAlso ; rdfs:subClassOf obo:CIDO_0000454 . obo:OBI_0000047 a rdfs:Class ; rdfs:label "processed material"@en ; rdfs:comment "Is a material entity that is created or changed during material processing."@en ; rdfs:subClassOf obo:BFO_0000040 . a rdfs:Class ; rdfs:label "Parasitic Diseases [Disease/Finding]" ; rdfs:subClassOf obo:IDO_0000436 . obo:OPMI_0000568 a rdfs:Class ; rdfs:label "drug exposure end datetime"@en ; rdfs:comment "The date and time on which a drug exposure ends for a patient." ; rdfs:subClassOf obo:OPMI_0000564 . obo:CIDO_0000262 a rdfs:Class ; rdfs:label "COVID-19 serological diagnostic assay"@en ; rdfs:comment "A COVID-19 diagnostic array that tests the serum from the blood specimen" ; rdfs:subClassOf obo:CIDO_0000258 . a rdfs:Class ; rdfs:label "Cardiac Rhythm Alteration [PE]" ; rdfs:subClassOf . obo:CIDO_0001077 a rdfs:Class ; rdfs:label "AA variant in SARS-CoV-2 nsp6 protein"@en ; rdfs:comment "An AA variant in SARS-CoV-2 nsp6 protein. Equivalent to an AA variant in SARS-CoV-2 rep 1ab with an AA position of 3547 - 3836." ; rdfs:subClassOf obo:CIDO_0000714 . obo:CHEBI_47724 a rdfs:Class ; rdfs:label "vancomycin aglycone" ; rdfs:comment "A peptide antibiotic that is vancomycin lacking the disaccharide moiety." ; rdfs:subClassOf obo:CHEBI_24533 , obo:CHEBI_25903 , obo:CHEBI_26195 , obo:CHEBI_37407 . obo:CHEBI_35543 a rdfs:Class ; rdfs:label "cardanolide" ; rdfs:subClassOf obo:CHEBI_26766 , obo:CHEBI_35508 . obo:IDO_0000602 a rdfs:Class ; rdfs:label "host exposure to substance that might have infectious agent"@en ; rdfs:comment "A host exposure to environment with infectious agent where the environment contains a material entity that has been assessed to confer a risk of infection."@en ; rdfs:subClassOf obo:IDO_0000597 . obo:CHEBI_24099 a rdfs:Class ; rdfs:label "formyltetrahydrofolic acid" ; rdfs:subClassOf obo:CHEBI_26907 . obo:ENVO_01000798 a rdfs:Class ; rdfs:label "plasma"@en ; rdfs:comment "A material entity which is composed of a volume of unbound positive and negative particles in roughly equal numbers, conducts electricity, and possesses internal magnetic fields." ; rdfs:subClassOf obo:ENVO_02000140 . obo:CIDO_0000982 a rdfs:Class ; rdfs:label "SARS-CoV2 orf6 protein binding to human NUP98" ; rdfs:comment "SARS-CoV2 orf6 protein binding to human NUP98, as evidented by an affinity-purification mass spectrometry experiment" ; rdfs:subClassOf obo:CIDO_0000586 . obo:CHEBI_33842 a rdfs:Class ; rdfs:label "aromatic annulene" ; rdfs:subClassOf obo:CHEBI_33662 , obo:CHEBI_33847 . obo:NCBITaxon_903631 a rdfs:Class ; rdfs:label "Kenya bat coronavirus BtKY93" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:HP_0005147 a rdfs:Class ; rdfs:label "Bidirectional ventricular ectopy" ; rdfs:subClassOf obo:HP_0004308 . obo:NCBITaxon_903581 a rdfs:Class ; rdfs:label "Kenya bat coronavirus BtKY113" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:PR_Q96LZ3 a rdfs:Class ; rdfs:label "calcineurin subunit B type 2 (human)" ; rdfs:comment "A calcineurin subunit B type 2 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000013151 , obo:PR_000029067 . obo:ENVO_02000140 a rdfs:Class ; rdfs:label "fluid environmental material"@en ; rdfs:comment "A liquid or a gas." ; rdfs:subClassOf obo:ENVO_00010483 . obo:PR_P05362 a rdfs:Class ; rdfs:label "intercellular adhesion molecule 1 (human)" ; rdfs:comment "An intercellular adhesion molecule 1 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000001467 , obo:PR_000029067 . obo:PR_000029945 a rdfs:Class ; rdfs:label "glutathione S-transferase" ; rdfs:comment "A protein that is capable of conjugating the reduced form of glutathione (GSH) to a substrate." ; rdfs:subClassOf obo:PR_000000001 . obo:VO_0000532 a rdfs:Class ; rdfs:label "subcutaneous route" ; rdfs:comment "a route of administration that is loacted in the hypodermis (subcutaneous tissue) region. " ; rdfs:subClassOf obo:VO_0000574 . obo:CIDO_0020022 a rdfs:Class ; rdfs:label "Ambry COVID-19 RT-PCR Test" ; rdfs:seeAlso ; rdfs:subClassOf obo:CIDO_0000454 . obo:NCBITaxon_12663 a rdfs:Class ; rdfs:label "Feline coronavirus" ; rdfs:subClassOf obo:NCBITaxon_693997 . obo:CIDO_0020049 a rdfs:Class ; rdfs:label "BioCheck SARS-CoV-2 IgG Antibody Test Kit" ; rdfs:seeAlso ; rdfs:subClassOf obo:CIDO_0000454 . obo:PR_000001901 a rdfs:Class ; rdfs:label "nitric oxide synthase, inducible" ; rdfs:comment "A protein that is a translation product of the human NOS2 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:PR_000001933 a rdfs:Class ; rdfs:label "signal transducer and transcription activator STAT" ; rdfs:comment "A protein with core architecture consisting of a STAT protein, protein interaction domain (Pfam:PF02865), an SH2 domain (Pfam:PF01017), a STAT protein, DNA binding domain (Pfam:PF02864), and a second SH2 domain." ; rdfs:subClassOf obo:PR_000000001 . obo:CHEBI_26191 a rdfs:Class ; rdfs:label "polyol" ; rdfs:comment "A compound that contains three or more hydroxyl groups." ; rdfs:subClassOf obo:CHEBI_30879 , obo:CHEBI_33822 . obo:VO_0005249 a rdfs:Class ; rdfs:label "EXG-5003"@en ; rdfs:comment "A SARS-COV-2 temperature-sensitive self-replicating RNA vaccine expressing the receptor binding domain of the SARS-CoV-2 spike protein." ; rdfs:subClassOf obo:VO_0005198 . obo:CHEBI_33576 a rdfs:Class ; rdfs:label "sulfur-containing carboxylic acid" ; rdfs:comment "Any carboxylic acid having a sulfur substituent." ; rdfs:subClassOf obo:CHEBI_33261 , obo:CHEBI_33575 . obo:GO_0045071 a rdfs:Class ; rdfs:label "negative regulation of viral genome replication" ; rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of viral genome replication." ; rdfs:subClassOf obo:GO_0045069 , obo:GO_0048525 . obo:CIDO_0000571 a rdfs:Class ; rdfs:label "AQIDRLINGRLTALN" ; rdfs:comment "A coronavirus epitope that is part of some S protein from HCoV OC43 composed of the following amino acids AQIDRLINGRLTALN" ; rdfs:subClassOf obo:CIDO_0000452 . obo:CIDO_0000513 a rdfs:Class ; rdfs:label "AWRFPCAGRKVNFNE" ; rdfs:comment "A coronavirus epitope that is part of some S protein from HCoV HKU1 composed of the following amino acids AWRFPCAGRKVNFNE" ; rdfs:subClassOf obo:CIDO_0000409 . obo:NCBITaxon_169863 a rdfs:Class ; rdfs:label "Colubrinae" ; rdfs:subClassOf obo:NCBITaxon_8578 . obo:CHEBI_143819 a rdfs:Class ; rdfs:label "C-terminal amino acid residue(1-)" ; rdfs:subClassOf obo:CHEBI_35416 . a rdfs:Class ; rdfs:label "Urological Manifestations [Disease/Finding]" ; rdfs:subClassOf . obo:UBERON_0001359 a rdfs:Class ; rdfs:label "cerebrospinal fluid" ; rdfs:comment "A clear, colorless, bodily fluid, that occupies the subarachnoid space and the ventricular system around and inside the brain and spinal cord." ; rdfs:subClassOf obo:UBERON_0006314 . obo:CIDO_0000303 a rdfs:Class ; rdfs:label "HCoV OC43 epitope"@en ; rdfs:subClassOf obo:CIDO_0000300 . obo:RO_0000053 a rdf:Property ; rdfs:label "bearer of"@en ; rdfs:comment "a relation between an independent continuant (the bearer) and a specifically dependent continuant (the dependent), in which the dependent specifically depends on the bearer for its existence"@en ; rdfs:range obo:BFO_0000020 . obo:NCBITaxon_1679893 a rdfs:Class ; rdfs:label "Coronavirus RCoV/D_RMU10_1985/Myo_gla/GER/2010" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:NCBITaxon_864617 a rdfs:Class ; rdfs:label "Bat coronavirus BR98-53/BGR/2008" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:CHEBI_22315 a rdfs:Class ; rdfs:label "alkaloid" ; rdfs:comment "Any of the naturally occurring, basic nitrogen compounds (mostly heterocyclic) occurring mostly in the plant kingdom, but also found in bacteria, fungi, and animals. By extension, certain neutral compounds biogenetically related to basic alkaloids are also classed as alkaloids. Amino acids, peptides, proteins, nucleotides, nucleic acids, amino sugars and antibiotics are not normally regarded as alkaloids. Compounds in which the nitrogen is exocyclic (dopamine, mescaline, serotonin, etc.) are usually classed as amines rather than alkaloids." ; rdfs:subClassOf obo:CHEBI_35352 . obo:GO_0048584 a rdfs:Class ; rdfs:label "positive regulation of response to stimulus" ; rdfs:comment "Any process that activates, maintains or increases the rate of a response to a stimulus. Response to stimulus is a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus." ; rdfs:subClassOf obo:GO_0048518 , obo:GO_0048583 . a rdfs:Class ; rdfs:label "Poisoning [Disease/Finding]" ; rdfs:subClassOf . obo:NCBITaxon_681848 a rdfs:Class ; rdfs:label "Kenya bat coronavirus BtKY01" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:CIDO_0020258 a rdfs:Class ; rdfs:label "RapCov Rapid COVID-19 Test" ; rdfs:seeAlso ; rdfs:subClassOf obo:CIDO_0000454 . obo:CIDO_0000601 a rdfs:Class ; rdfs:label "AA variant in SARS-CoV-2 NS7 protein"@en ; rdfs:subClassOf obo:CIDO_0000237 . a rdfs:Class ; rdfs:label "Drug Toxicity [Disease/Finding]" ; rdfs:subClassOf . obo:PR_Q9NW13 a rdfs:Class ; rdfs:label "RNA-binding protein 28 (human)" ; rdfs:comment "An RNA-binding protein 28 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000013793 , obo:PR_000029067 . obo:CHEBI_33482 a rdfs:Class ; rdfs:label "sulfur oxoanion" ; rdfs:subClassOf obo:CHEBI_26835 , obo:CHEBI_33485 . obo:CHEBI_25389 a rdfs:Class ; rdfs:label "monohydroxybenzoic acid" ; rdfs:comment "Any hydroxybenzoic acid having a single phenolic hydroxy substituent on the benzene ring." ; rdfs:subClassOf obo:CHEBI_24676 . obo:VO_0004992 a rdfs:Class ; rdfs:label "CoVLP"@en ; rdfs:comment "A recombinant coronavirus-like particle SARS-CoV-2 vaccine developed by Medicago" ; rdfs:subClassOf obo:VO_0005418 . obo:PR_000000036 a rdfs:Class ; rdfs:label "BMP receptor type-1B" ; rdfs:comment "A TGF-beta superfamily receptor type-1 that is a translation product of the human BMPR1B gene or a 1:1 ortholog thereof. Bone morphogenetic protein (BMP) signals are transmitted by type 2 and type 1 serine/threonine kinase receptors. Type 2 receptors phosphorylate and activate type 1 receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for BMPS/OP-1." ; rdfs:subClassOf obo:PR_000000006 . obo:PR_000029807 a rdfs:Class ; rdfs:label "TM2 domain-containing protein 3" ; rdfs:comment "A protein that is a translation product of the human TM2D3 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:PR_P31995 a rdfs:Class ; rdfs:label "low affinity immunoglobulin gamma Fc region receptor II-c (human)" ; rdfs:comment "A low affinity immunoglobulin gamma Fc region receptor II-c that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000001482 , obo:PR_000029067 . obo:CIDO_0000370 a rdfs:Class ; rdfs:label "medical gown"@en ; rdfs:comment "A respirator designed to protect the user from breathing in contaminants in the air, thus preserving the health of their respiratory tract." ; rdfs:subClassOf obo:CIDO_0000365 . obo:NCBITaxon_1346298 a rdfs:Class ; rdfs:label "Betacoronavirus BtCoV/Rhi_eur/BB98-98/BGR/2008" ; rdfs:subClassOf obo:NCBITaxon_696098 . obo:GO_0006468 a rdfs:Class ; rdfs:label "protein phosphorylation" ; rdfs:comment "The process of introducing a phosphate group on to a protein." ; rdfs:subClassOf obo:GO_0006464 , obo:GO_0006796 . obo:CIDO_0020156 a rdfs:Class ; rdfs:label "GK ACCU-RIGHT SARS-CoV-2 RT-PCR KIT" ; rdfs:seeAlso ; rdfs:subClassOf obo:CIDO_0000454 . obo:IDO_0000495 a rdfs:Class ; rdfs:label "infectious disease course"@en ; rdfs:comment "A disease course that is the realization of an infectious disease."@en ; rdfs:subClassOf obo:OGMS_0000063 . obo:NCBITaxon_1788422 a rdfs:Class ; rdfs:label "Bat coronavirus MfulBtCoV/3759-1" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:CHEBI_73474 a rdfs:Class ; rdfs:label "acetylenic compound" ; rdfs:comment "Any organic molecule containing a C#C bond." ; rdfs:subClassOf obo:CHEBI_72695 . obo:PATO_0001018 a rdfs:Class ; rdfs:label "physical quality" ; rdfs:comment "A quality of a physical entity that exists through action of continuants at the physical level of organisation in relation to other entities." ; rdfs:subClassOf obo:PATO_0001241 . obo:NCBITaxon_300190 a rdfs:Class ; rdfs:label "Bird droppings coronavirus" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:CIDO_0001221 a rdfs:Class ; rdfs:label "SARS-CoV-2 Nucleic Acid Detection Kit RNA (RNA isothermal amplification-gold probe chromatography) (Wuhan Zhongzhi Biotechnologies INC.)" ; rdfs:comment "Manufacturor: Wuhan Zhongzhi Biotechnologies INC. 武汉中帜生物科技股份有限公司" ; rdfs:subClassOf obo:CIDO_0000021 . obo:CHEBI_32860 a rdfs:Class ; rdfs:label "valinium" ; rdfs:subClassOf obo:CHEBI_33719 . obo:DRON_00015413 a rdfs:Class ; rdfs:label "nitazoxanide" ; rdfs:subClassOf obo:OBI_0000047 . obo:PR_000007886 a rdfs:Class ; rdfs:label "GRIP and coiled-coil domain-containing protein 1" ; rdfs:comment "A protein that is a translation product of the human GCC1 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:CIDO_0001066 a rdfs:Class ; rdfs:label "SARS-CoV2 orf9c protein binding to human TMEM39B" ; rdfs:comment "SARS-CoV2 orf9c protein binding to human TMEM39B, as evidented by an affinity-purification mass spectrometry experiment" ; rdfs:subClassOf obo:CIDO_0000054 . obo:CIDO_0001102 a rdfs:Class ; rdfs:label "SARS-CoV2 orf8 protein binding to human HYOU1"@en ; rdfs:comment "SARS-CoV2 orf8 protein binding to human HYOU1, as evidented by an affinity-purification mass spectrometry experiment" ; rdfs:subClassOf obo:CIDO_0000051 . obo:PR_Q92615 a rdfs:Class ; rdfs:label "La-related protein 4B (human)" ; rdfs:comment "A La-related protein 4B that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000009671 , obo:PR_000029067 . a rdfs:Class ; rdfs:label "Intercellular Signaling Peptides and Proteins [Chemical/Ingredient]" ; rdfs:subClassOf , , . obo:CHEBI_35655 a rdfs:Class ; rdfs:label "conanine" ; rdfs:subClassOf obo:CHEBI_35341 , obo:CHEBI_38516 . obo:NCBITaxon_1269314 a rdfs:Class ; rdfs:label "Coronavirus BtCoV/KP534/Art_lit/PAN/2010" ; rdfs:subClassOf obo:NCBITaxon_2664420 . a rdfs:Class ; rdfs:label "Ivermectin [Chemical/Ingredient]" ; rdfs:subClassOf . obo:CHEBI_3738 a rdfs:Class ; rdfs:label "clemastine" ; rdfs:comment "2-[(2R)-1-Methylpyrrolidin-2-yl]ethanol in which the hydrogen of the hydroxy group is substituted by a 1-(4-chlorophenyl)-1-phenylethyl group (R configuration). An antihistamine with antimuscarinic and moderate sedative properties, it is used as its fumarate salt for the symptomatic relief of allergic conditions such as rhinitis, urticaria, conjunctivitis and in pruritic (severe itching) skin conditions." ; rdfs:subClassOf obo:CHEBI_46775 , obo:CHEBI_83403 . obo:DRON_00723855 a rdfs:Class ; rdfs:label "cytochrome P450 isoenzyme 2C19 (CYP2C19) substrate disposition" ; rdfs:subClassOf obo:BFO_0000016 . obo:NCBITaxon_249072 a rdfs:Class ; rdfs:label "SARS coronavirus HZS2-Fb" ; rdfs:subClassOf obo:NCBITaxon_694009 . obo:GO_0031295 a rdfs:Class ; rdfs:label "T cell costimulation" ; rdfs:comment "The process of providing, via surface-bound receptor-ligand pairs, a second, antigen-independent, signal in addition to that provided by the T cell receptor to augment T cell activation." ; rdfs:subClassOf obo:GO_0031294 , obo:GO_0050870 . obo:VO_0005410 a rdfs:Class ; rdfs:label "SYS6006"@en ; rdfs:comment "A SARS-CoV-2 mRNA vaccine by CSPC ZhongQi Pharmaceutical Technology Co., Ltd." ; rdfs:subClassOf obo:VO_0005198 . a rdfs:Class ; rdfs:label "Adamantane [Chemical/Ingredient]" ; rdfs:subClassOf , . obo:PR_000007767 a rdfs:Class ; rdfs:label "gamma-aminobutyric acid receptor subunit alpha-2" ; rdfs:comment "A GABA(A) receptor protein that is a translation product of the human GABRA2 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000044664 . obo:CIDO_0000895 a rdfs:Class ; rdfs:label "SARS-CoV2 nsp7 protein binding to human CYB5R3" ; rdfs:comment "SARS-CoV2 nsp7 protein binding to human CYB5R3, as evidented by an affinity-purification mass spectrometry experiment" ; rdfs:subClassOf obo:CIDO_0000049 . obo:PR_Q9NQT4 a rdfs:Class ; rdfs:label "exosome complex component RRP46 (human)" ; rdfs:comment "An exosome complex component RRP46 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000007262 , obo:PR_000029067 . obo:NCBITaxon_1269297 a rdfs:Class ; rdfs:label "Coronavirus BtCoV/BRA182/Mol_ruf/BRA/2009" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:PR_P61026 a rdfs:Class ; rdfs:label "Ras-related protein Rab-10 (human)" ; rdfs:comment "A Ras-related protein Rab-10 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000013578 , obo:PR_000029067 . obo:NCBITaxon_11127 a rdfs:Class ; rdfs:label "Avian infectious bronchitis virus (strain M41)" ; rdfs:subClassOf obo:NCBITaxon_11120 . obo:CHEBI_17790 a rdfs:Class ; rdfs:label "methanol" ; rdfs:comment "The primary alcohol that is the simplest aliphatic alcohol, comprising a methyl and an alcohol group." ; rdfs:subClassOf obo:CHEBI_134179 , obo:CHEBI_15734 , obo:CHEBI_50584 , obo:CHEBI_64708 . obo:OBI_0400106 a rdfs:Class ; rdfs:label "centrifuge" ; rdfs:comment "A device with a rapidly rotating container that applies centrifugal force to its contents" ; rdfs:subClassOf obo:OBI_0000832 , obo:OBI_0000932 . a rdfs:Class ; rdfs:label "Nausea [Disease/Finding]" ; rdfs:subClassOf . obo:NCBITaxon_1788467 a rdfs:Class ; rdfs:label "Miniopterus bat coronavirus BtCoV/3760-1" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:PR_000005257 a rdfs:Class ; rdfs:label "cell division protein kinase 4" ; rdfs:comment "A CDK2-related kinase that is a translation product of the human CDK4 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000003270 . obo:NCBITaxon_727988 a rdfs:Class ; rdfs:label "Ferret enteric coronavirus 1202" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:NCBITaxon_10095 a rdfs:Class ; rdfs:label "Mus sp." ; rdfs:subClassOf obo:NCBITaxon_941326 . obo:NCBITaxon_622713 a rdfs:Class ; rdfs:label "Bat coronavirus Hipposideros/GhanaKwam/22/2008" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:CHEBI_15939 a rdfs:Class ; rdfs:label "glycyrrhizinic acid" ; rdfs:comment "A triterpenoid saponin that is the glucosiduronide derivative of 3beta-hydroxy-11-oxoolean-12-en-30-oic acid." ; rdfs:subClassOf obo:CHEBI_24302 , obo:CHEBI_25872 , obo:CHEBI_27093 , obo:CHEBI_51689 , obo:CHEBI_61778 . obo:CHEBI_46952 a rdfs:Class ; rdfs:label "oxazinane" ; rdfs:subClassOf obo:CHEBI_25693 , obo:CHEBI_38101 , obo:CHEBI_38104 . obo:CHEBI_37176 a rdfs:Class ; rdfs:label "mononuclear parent hydride" ; rdfs:subClassOf obo:CHEBI_33692 . obo:CIDO_0000591 a rdfs:Class ; rdfs:label "AA variant in SARS-CoV-2 S protein"@en ; rdfs:comment "An AA variant that is located in theSARS-CoV-2 S protein." ; rdfs:subClassOf obo:CIDO_0000237 . obo:CIDO_0000547 a rdfs:Class ; rdfs:label "LLFDVIVAWHVVRDP" ; rdfs:comment "A coronavirus epitope that is part of some S protein from HCoV OC43 composed of the following amino acids LLFDVIVAWHVVRDP" ; rdfs:subClassOf obo:CIDO_0000452 . a rdfs:Class ; rdfs:label "Diarrhea [Disease/Finding]" ; rdfs:subClassOf . obo:NCBITaxon_1679910 a rdfs:Class ; rdfs:label "Coronavirus RCoV/LEO/Rat_sik/CHN/2007" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:CHEBI_24043 a rdfs:Class ; rdfs:label "flavones" ; rdfs:comment "A member of the class of flavonoid with a 2-aryl-1-benzopyran-4-one (2-arylchromen-4-one) skeleton and its substituted derivatives." ; rdfs:subClassOf obo:CHEBI_47916 . obo:HP_0040088 a rdfs:Class ; rdfs:label "Abnormal lymphocyte count" ; rdfs:comment "Any abnormality in the total number of lymphocytes in the blood." ; rdfs:subClassOf obo:HP_0001881 , obo:HP_0011893 . a rdfs:Class ; rdfs:label "Skin Diseases, Metabolic [Disease/Finding]" ; rdfs:subClassOf , . obo:CHEBI_33595 a rdfs:Class ; rdfs:label "cyclic compound" ; rdfs:comment "Any molecule that consists of a series of atoms joined together to form a ring." ; rdfs:subClassOf obo:CHEBI_25367 , obo:CHEBI_36357 . obo:CHEBI_63941 a rdfs:Class ; rdfs:label "22,23-dihydroavermectin B1a" ; rdfs:comment "A macrocyclic lactone that is avermectin B1a in which the double bond present in the spirocyclic ring system has been reduced to a single bond. It is the major component of ivermectin." ; rdfs:subClassOf obo:CHEBI_63944 , obo:CHEBI_72600 . obo:NCBITaxon_1052157 a rdfs:Class ; rdfs:label "Feline coronavirus UU47" ; rdfs:subClassOf obo:NCBITaxon_12663 . obo:CIDO_0000993 a rdfs:Class ; rdfs:label "SARS-CoV2 orf8 protein binding to human EDEM3" ; rdfs:comment "SARS-CoV2 orf8 protein binding to human EDEM3, as evidented by an affinity-purification mass spectrometry experiment" ; rdfs:subClassOf obo:CIDO_0000051 . obo:CIDO_0000489 a rdfs:Class ; rdfs:label "CGIKYVAQPTEDVVD" ; rdfs:comment "A coronavirus epitope that is part of some S protein from HCoV HKU1 composed of the following amino acids CGIKYVAQPTEDVVD" ; rdfs:subClassOf obo:CIDO_0000409 . obo:CIDO_0000927 a rdfs:Class ; rdfs:label "SARS-CoV2 nsp8 protein binding to human EXOSC2" ; rdfs:comment "SARS-CoV2 nsp8 protein binding to human EXOSC2, as evidented by an affinity-purification mass spectrometry experiment" ; rdfs:subClassOf obo:CIDO_0000582 . obo:VO_0005265 a rdfs:Class ; rdfs:label "authorized COVID-19 RNA vaccine"@en ; rdfs:subClassOf obo:VO_0005198 , obo:VO_0005264 . obo:CHEBI_17387 a rdfs:Class ; rdfs:label "O-acylcarnitine" ; rdfs:comment "Any carboxylic ester obtained by the O-acylation of carnitine." ; rdfs:subClassOf obo:CHEBI_33308 , obo:CHEBI_35284 . obo:CIDO_0000699 a rdfs:Class ; rdfs:label "T20N in SARS-CoV-2 S protein" ; rdfs:comment "An AA mutation or AA variant that has mutated an amino acid at position 20 into a aspargine in S protein." ; rdfs:subClassOf obo:CIDO_0000594 . obo:OGMS_0000073 a rdfs:Class ; rdfs:label "diagnosis" ; rdfs:comment "The representation of a conclusion of a diagnostic process."@en ; rdfs:subClassOf obo:IAO_0000027 . obo:CHEBI_50830 a rdfs:Class ; rdfs:label "fluorinated steroid" ; rdfs:comment "A steroid which is substituted with one or more fluorine atoms in any position." ; rdfs:subClassOf obo:CHEBI_35341 , obo:CHEBI_37143 . obo:VO_0005186 a rdfs:Class ; rdfs:label "Covigenix VAX-001"@en ; rdfs:comment "A prophylactic plasmid DNA Vaccine for SARS CoV-2 by Entos Pharmaceuticals" ; rdfs:subClassOf obo:VO_0005203 . obo:CHEBI_32657 a rdfs:Class ; rdfs:label "D-asparaginium" ; rdfs:subClassOf obo:CHEBI_32661 . obo:CIDO_0000658 a rdfs:Class ; rdfs:label "A570D in SARS-CoV-2 S protein" ; rdfs:comment "An AA mutation or AA variant that has mutated an amino acid at position 570 into aspartic acid in S protein." ; rdfs:subClassOf obo:CIDO_0001155 . obo:VO_0005233 a rdfs:Class ; rdfs:label "mRNA-1273.351"@en ; rdfs:comment "A SARS-CoV-2 lipid nanoparticle (LNP)-encapsulated mRNA-based vaccine that encodes for a full-length, prefusion stabilized S protein of the SARS-CoV-2 B.1.351 variant" ; rdfs:subClassOf obo:VO_0005198 . obo:PR_000012961 a rdfs:Class ; rdfs:label "DNA polymerase alpha subunit B" ; rdfs:comment "A protein that is a translation product of the human POLA2 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . a rdfs:Class ; rdfs:label "HYDROXYPROGESTERONE" ; rdfs:subClassOf . obo:CHEBI_76906 a rdfs:Class ; rdfs:label "EC 4.1.1.* (carboxy-lyase) inhibitor" ; rdfs:comment "An EC 4.1.* (C-C lyase) inhibitor that interferes with the action of any carboxy-lyase (EC 4.1.1.*)." ; rdfs:subClassOf obo:CHEBI_76711 . obo:HP_0025478 a rdfs:Class ; rdfs:label "Atrial standstill"@en ; rdfs:comment "Atrial standstill or silent atrium is a rare condition presenting with the absence of electrical and mechanical activity in the atria. It presents with the absence of P waves, bradycardia, and wide QRS complex in the electrocardiogram." ; rdfs:subClassOf obo:HP_0005115 . obo:DOID_9478 a rdfs:Class ; rdfs:label "postpartum depression" ; rdfs:comment "An endogenous depression that involves intense, sustained and sometimes disabling depression experienced by women after giving birth." ; rdfs:subClassOf obo:DOID_1595 . obo:CIDO_0000874 a rdfs:Class ; rdfs:label "SARS-CoV2 nsp2 protein binding to human SLC27A2" ; rdfs:comment "SARS-CoV2 nsp2 protein binding to human SLC27A2, as evidented by an affinity-purification mass spectrometry experiment" ; rdfs:subClassOf obo:CIDO_0000580 . obo:CHEBI_26151 a rdfs:Class ; rdfs:label "piperidines" ; rdfs:subClassOf obo:CHEBI_25693 , obo:CHEBI_38101 . obo:NCBITaxon_2732396 a rdfs:Class ; rdfs:label "Orthornavirae" ; rdfs:subClassOf obo:NCBITaxon_2559587 . obo:GO_0006725 a rdfs:Class ; rdfs:label "cellular aromatic compound metabolic process" ; rdfs:comment "The chemical reactions and pathways involving aromatic compounds, any organic compound characterized by one or more planar rings, each of which contains conjugated double bonds and delocalized pi electrons, as carried out by individual cells." ; rdfs:subClassOf obo:GO_0044237 . obo:IAO_0000132 a rdfs:Class ; rdfs:label "lot number"@en ; rdfs:comment "A lot number is an information content entity which is an identical sequence of character borne by part of manufactured product or its packaging for each instances of a product class in a discrete batch of an item. Lot numbers are usually assigned to each separate production run of an item. Manufacturing as a lot might be due to a variety of reasons, for example, a single process during which many individuals are made from the same portion of source material. Lot numbers can be encoded in a pattern of other information objects, such as bar codes, numerals, or patterns of dots."@en ; rdfs:subClassOf obo:IAO_0000028 . a rdfs:Class ; rdfs:label "Bufanolides [Chemical/Ingredient]" ; rdfs:subClassOf . obo:VO_0005403 a rdfs:Class ; rdfs:label "RVM-V001"@en ; rdfs:comment "A SARS-CoV-2 RNA vaccine by RVAC Medicines" ; rdfs:subClassOf obo:VO_0005198 . obo:NCBITaxon_875614 a rdfs:Class ; rdfs:label "Bat coronavirus HKU9-5-1" ; rdfs:subClassOf obo:NCBITaxon_694006 . obo:GO_0008283 a rdfs:Class ; rdfs:label "cell population proliferation" ; rdfs:comment "The multiplication or reproduction of cells, resulting in the expansion of a cell population." ; rdfs:subClassOf obo:GO_0009987 . a rdfs:Class ; rdfs:label "Congenital Abnormalities [Disease/Finding]" ; rdfs:subClassOf . obo:PR_000029062 a rdfs:Class ; rdfs:label "Escherichia coli K-12 protein" ; rdfs:comment "A protein that is encoded in the genome of Escherichia coli K-12." ; rdfs:subClassOf obo:PR_000036195 . obo:GO_0007610 a rdfs:Class ; rdfs:label "behavior" ; rdfs:comment "The internally coordinated responses (actions or inactions) of animals (individuals or groups) to internal or external stimuli, via a mechanism that involves nervous system activity." ; rdfs:subClassOf obo:GO_0032501 . obo:NCBITaxon_1532171 a rdfs:Class ; rdfs:label "Alphacoronavirus BtCoV/GrNC8/Neo_cap/RSA/2012" ; rdfs:subClassOf obo:NCBITaxon_366617 . obo:PR_P40238 a rdfs:Class ; rdfs:label "thrombopoietin receptor (human)" ; rdfs:comment "A thrombopoietin receptor that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000001939 , obo:PR_000029067 . a rdfs:Class ; rdfs:label "Malaria, Vivax [Disease/Finding]" ; rdfs:subClassOf . obo:CHEBI_48591 a rdfs:Class ; rdfs:label "N-acylpiperidine" ; rdfs:subClassOf obo:CHEBI_26151 , obo:CHEBI_32988 . obo:PR_000011192 a rdfs:Class ; rdfs:label "neuroguidin" ; rdfs:comment "A protein that is a translation product of the human NGDN gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:NCBITaxon_305407 a rdfs:Class ; rdfs:label "SARS coronavirus B024" ; rdfs:subClassOf obo:NCBITaxon_694009 . obo:PR_Q9NYU1 a rdfs:Class ; rdfs:label "UDP-glucose:glycoprotein glucosyltransferase 2 (human)" ; rdfs:comment "A UDP-glucose:glycoprotein glucosyltransferase 2 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000017045 , obo:PR_000029067 . obo:CHEBI_46773 a rdfs:Class ; rdfs:label "hydroxypyrrolidine" ; rdfs:subClassOf obo:CHEBI_38260 . a rdfs:Class ; rdfs:label "Lentivirus Infections [Disease/Finding]" ; rdfs:subClassOf . obo:CHEBI_131927 a rdfs:Class ; rdfs:label "dicarboxylic acids and O-substituted derivatives" ; rdfs:comment "A class of carbonyl compound encompassing dicarboxylic acids and any derivatives obtained by substitution of either one or both of the carboxy hydrogens." ; rdfs:subClassOf obo:CHEBI_36586 . obo:NCBITaxon_1288696 a rdfs:Class ; rdfs:label "Bat coronavirus POA/2012/D09" ; rdfs:subClassOf obo:NCBITaxon_366617 . obo:PR_000050277 a rdfs:Class ; rdfs:label "non-structural protein 8 (SARS-CoV-2)" ; rdfs:comment "A rep gene proteolytic cleavage product (SARS-CoV-2) that is the central portion produced by the enzymatic action of 3CL-PRO proteinase (nsp5) when it cleaves the precursor rep gene translation product (SARS-CoV-2) between residues 3942-3943 and 4140-4141." ; rdfs:subClassOf obo:PR_000050281 . obo:NCBITaxon_258966 a rdfs:Class ; rdfs:label "SARS coronavirus TW3" ; rdfs:subClassOf obo:NCBITaxon_694009 . obo:CIDO_0020215 a rdfs:Class ; rdfs:label "Novel Coronavirus (2019-nCoV) Nucleic Acid Diagnostic Kit (PCR-Fluorescence Probing)" ; rdfs:seeAlso ; rdfs:subClassOf obo:CIDO_0000454 . obo:CHEBI_38068 a rdfs:Class ; rdfs:label "antimalarial" ; rdfs:comment "A drug used in the treatment of malaria. Antimalarials are usually classified on the basis of their action against Plasmodia at different stages in their life cycle in the human." ; rdfs:subClassOf obo:CHEBI_64915 . obo:CHEBI_138015 a rdfs:Class ; rdfs:label "endocrine disruptor" ; rdfs:comment "Any compound that can disrupt the functions of the endocrine (hormone) system" ; rdfs:subClassOf obo:CHEBI_51061 . obo:GO_0044272 a rdfs:Class ; rdfs:label "sulfur compound biosynthetic process" ; rdfs:comment "The chemical reactions and pathways resulting in the formation of compounds that contain sulfur, such as the amino acids methionine and cysteine or the tripeptide glutathione." ; rdfs:subClassOf obo:GO_0006790 , obo:GO_0044249 . obo:CHEBI_50341 a rdfs:Class ; rdfs:label "1-hydroxyethyl group" ; rdfs:subClassOf obo:CHEBI_50325 . obo:NCBITaxon_1541208 a rdfs:Class ; rdfs:label "Bat Hp-betacoronavirus/Zhejiang2013-3" ; rdfs:subClassOf obo:NCBITaxon_696098 . obo:HP_0100753 a rdfs:Class ; rdfs:label "Schizophrenia" ; rdfs:comment "A mental disorder characterized by a disintegration of thought processes and of emotional responsiveness. It most commonly manifests as auditory hallucinations, paranoid or bizarre delusions, or disorganized speech and thinking, and it is accompanied by significant social or occupational dysfunction. The onset of symptoms typically occurs in young adulthood, with a global lifetime prevalence of about 0.3-0.7%." ; rdfs:subClassOf obo:HP_0000708 . obo:OBI_0002613 a rdfs:Class ; rdfs:label "environmental swab specimen" ; rdfs:comment "A specimen that is collected with a swab from the surface of an environmenal material." ; rdfs:subClassOf obo:OBI_0002599 . obo:PR_P08912 a rdfs:Class ; rdfs:label "muscarinic acetylcholine receptor M5 (human)" ; rdfs:comment "A muscarinic acetylcholine receptor M5 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000001617 , obo:PR_000029067 . obo:PR_P0DTG1 a rdfs:Class ; rdfs:label "ORF3c protein (SARS-CoV-2)" ; rdfs:comment "A protein that is a translation product of the ORF3c gene in SARS-CoV-2." ; rdfs:subClassOf obo:PR_000050262 . obo:NCBITaxon_1788472 a rdfs:Class ; rdfs:label "Miniopterus bat coronavirus BtCoV/4001-2" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:PR_000010527 a rdfs:Class ; rdfs:label "mitochondrial amidoxime-reducing component 1" ; rdfs:comment "A protein that is a translation product of the human MTARC1 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . a rdfs:Class ; rdfs:label "Skin Diseases, Bacterial [Disease/Finding]" ; rdfs:subClassOf , . a rdfs:Class ; rdfs:label "Benzoic Acids [Chemical/Ingredient]" ; rdfs:subClassOf . obo:VO_0012183 a rdfs:Class ; rdfs:label "SARS vaccine" ; rdfs:comment "A vaccine that protects against SARS-CoV." ; rdfs:subClassOf obo:VO_0004897 . obo:CIDO_0000535 a rdfs:Class ; rdfs:label "NPPTNVVSHVNGDWF" ; rdfs:comment "A coronavirus epitope that is part of some S protein from HCoV OC43 composed of the following amino acids NPPTNVVSHVNGDWF" ; rdfs:subClassOf obo:CIDO_0000452 . a rdfs:Class ; rdfs:label "Interferon-beta [Chemical/Ingredient]" ; rdfs:subClassOf . obo:CHEBI_52845 a rdfs:Class ; rdfs:label "cyclic organic group" ; rdfs:comment "An organic group that consists of a closed ring. It may be a substituent or a skeleton." ; rdfs:subClassOf obo:CHEBI_33247 . obo:GO_0034776 a rdfs:Class ; rdfs:label "response to histamine" ; rdfs:comment "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a histamine stimulus. Histamine, the biogenic amine 2-(1H-imidazol-4-yl)ethanamine, is involved in local immune responses as well as regulating physiological function in the gut and acting as a neurotransmitter." ; rdfs:subClassOf obo:GO_0010243 , obo:GO_0014070 . obo:PR_O14730 a rdfs:Class ; rdfs:label "serine/threonine-protein kinase RIO3 (human)" ; rdfs:comment "A serine/threonine-protein kinase RIO3 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000014021 , obo:PR_000029067 . obo:CIDO_0001088 a rdfs:Class ; rdfs:label "at-home over-the-counter COVID-19 diagnostic test device"@en ; rdfs:comment "at-home OTC COVID-19 diagnostic test device" ; rdfs:subClassOf obo:CIDO_0000453 . obo:CIDO_0000460 a rdfs:Class ; rdfs:label "APEGLVFLHTVLLPT" ; rdfs:comment "A coronavirus epitope that is part of some S protein from HCoV 229E composed of the following amino acids APEGLVFLHTVLLPT" ; rdfs:subClassOf obo:CIDO_0000451 . obo:CHEBI_24061 a rdfs:Class ; rdfs:label "fluorine atom" ; rdfs:subClassOf obo:CHEBI_24473 . obo:CIDO_0000001 a rdfs:Class ; rdfs:label "coronavirus infectious disease process"@en ; rdfs:comment "A disease process that is induced by coronavirus infection" ; rdfs:subClassOf obo:ICDO_0000001 . obo:CIDO_0000053 a rdf:Property ; rdfs:label "caused by infection with"@en ; rdfs:comment "An object property that represents the relation between a disease process and a pathogen where the disease process is caused by the infection with the pathogen." ; rdfs:range . obo:DRON_00723856 a rdfs:Class ; rdfs:label "cytochrome P450 isoenzyme 2D6 (CYP2D6) substrate disposition" ; rdfs:subClassOf obo:BFO_0000016 . obo:CIDO_0020187 a rdfs:Class ; rdfs:label "Lilly SARS-CoV-2 Assay" ; rdfs:seeAlso ; rdfs:subClassOf obo:CIDO_0000454 . obo:OBI_0302884 a rdfs:Class ; rdfs:label "extraction"@en ; rdfs:comment "A material separation in which a desired component of an input material is separated from the remainder" ; rdfs:subClassOf obo:OBI_0600014 . obo:CIDO_0000647 a rdfs:Class ; rdfs:label "I1566V in SARS-CoV-2 pp1b protein" ; rdfs:comment "An AA mutation or AA variant that has mutated an amino acid at position 1566 into a valine in pp1b." ; rdfs:subClassOf obo:CIDO_0001085 . obo:PR_Q92570 a rdfs:Class ; rdfs:label "nuclear receptor subfamily 4 group A member 3 (human)" ; rdfs:comment "A nuclear receptor subfamily 4 group A member 3 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000011410 , obo:PR_000029067 . obo:PR_Q16816 a rdfs:Class ; rdfs:label "phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform (human)" ; rdfs:comment "A phosphorylase b kinase gamma catalytic chain, skeletal muscle isoform that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000012661 , obo:PR_000029067 . obo:CIDO_0020011 a rdfs:Class ; rdfs:label "ADVIA Centaur SARS-CoV-2 Total (COV2T)" ; rdfs:seeAlso ; rdfs:subClassOf obo:CIDO_0000454 . obo:CHEBI_58956 a rdfs:Class ; rdfs:label "branched-chain saturated fatty acid anion" ; rdfs:comment "Any saturated fatty acid anion with a carbon side-chain or isopropyl termination." ; rdfs:subClassOf obo:CHEBI_58953 , obo:CHEBI_58955 . obo:CHEBI_33306 a rdfs:Class ; rdfs:label "carbon group element atom" ; rdfs:subClassOf obo:CHEBI_33560 . obo:OPMI_0000586 a rdfs:Class ; rdfs:label "payer plan period start date"@en ; rdfs:comment "A date when a payer plan period starts." ; rdfs:subClassOf obo:OPMI_0000584 . obo:GO_2000249 a rdfs:Class ; rdfs:label "regulation of actin cytoskeleton reorganization" ; rdfs:comment "Any process that modulates the frequency, rate or extent of actin cytoskeleton reorganization." ; rdfs:subClassOf obo:GO_0050794 . a rdfs:Class ; rdfs:label "Increased Hematological Cell Destruction [PE]" ; rdfs:subClassOf . obo:CHEBI_59203 a rdfs:Class ; rdfs:label "straight-chain fatty acid anion" ; rdfs:comment "A fatty acid anion formed by deprotonation of the carboxylic acid functional group of a straight-chain fatty acid." ; rdfs:subClassOf obo:CHEBI_28868 . obo:NCBITaxon_1415839 a rdfs:Class ; rdfs:label "Bat SARS-like coronavirus Rs4081" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:CIDO_0000168 a rdfs:Class ; rdfs:label "experimental drug substance"@en ; rdfs:comment "A drug substance that is experinentallly proven to be effective against SARS-CoV-2 infection, where the experiment can be done either in vivo or in vitro. The in vitro study is typically conducted using cell line cells." ; rdfs:subClassOf obo:CIDO_0000167 . a rdfs:Class ; rdfs:label "Carbolines [Chemical/Ingredient]" ; rdfs:subClassOf , , . obo:NCBITaxon_1269311 a rdfs:Class ; rdfs:label "Coronavirus BtCoV/KCR91/Car_per/CRC/2010" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:CIDO_0000011 a rdfs:Class ; rdfs:label "COVID-19 drug role"@en ; rdfs:comment "A drug role that is realized in the treatment for COVID-19 disease. Here the treatment may include authorized drugs to be used clinically, drugs authorized for clinical trial usage, and drugs studied in an experimental setting." ; rdfs:subClassOf obo:CHEBI_23888 . obo:CHEBI_90799 a rdfs:Class ; rdfs:label "dipeptide zwitterion" ; rdfs:comment "Any peptide zwitterion comprising two amino acid residues. Major structure at pH 7.3." ; rdfs:subClassOf obo:CHEBI_60466 . obo:GO_0006402 a rdfs:Class ; rdfs:label "mRNA catabolic process" ; rdfs:comment "The chemical reactions and pathways resulting in the breakdown of mRNA, messenger RNA, which is responsible for carrying the coded genetic 'message', transcribed from DNA, to sites of protein assembly at the ribosomes." ; rdfs:subClassOf obo:GO_0006401 , obo:GO_0010629 , obo:GO_0016070 . a rdfs:Class ; rdfs:label "Anisomycin [Chemical/Ingredient]" ; rdfs:subClassOf . obo:PR_000008132 a rdfs:Class ; rdfs:label "golgin subfamily A member 3" ; rdfs:comment "A protein that is a translation product of the human GOLGA3 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:CIDO_0000416 a rdfs:Class ; rdfs:label "susceptibility to biological regulation"@en ; rdfs:comment "A disposition that a material entity such as a gene or protein is susceptible to be regulated" ; rdfs:subClassOf obo:BFO_0000016 . obo:GO_0043066 a rdfs:Class ; rdfs:label "negative regulation of apoptotic process" ; rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of cell death by apoptotic process." ; rdfs:subClassOf obo:GO_0042981 , obo:GO_0043069 . obo:NCBITaxon_1739614 a rdfs:Class ; rdfs:label "229E-related bat coronavirus" ; rdfs:subClassOf obo:NCBITaxon_11137 . obo:PR_Q96DA6 a rdfs:Class ; rdfs:label "mitochondrial import inner membrane translocase subunit TIM14 (human)" ; rdfs:comment "A mitochondrial import inner membrane translocase subunit TIM14 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000006582 , obo:PR_000029067 . obo:HP_0011703 a rdfs:Class ; rdfs:label "Sinus tachycardia" ; rdfs:comment "Heart rate of greater than 100 beats per minute." ; rdfs:subClassOf obo:HP_0011702 . obo:NCBITaxon_2591238 a rdfs:Class ; rdfs:label "Coronavirus BtRt-BetaCoV/GX2018" ; rdfs:subClassOf obo:NCBITaxon_2726811 . obo:GO_1901687 a rdfs:Class ; rdfs:label "glutathione derivative biosynthetic process" ; rdfs:comment "The chemical reactions and pathways resulting in the formation of glutathione derivative." ; rdfs:subClassOf obo:GO_0044272 , obo:GO_1901566 , obo:GO_1901685 . obo:NCBITaxon_1503282 a rdfs:Class ; rdfs:label "BtMf-AlphaCoV/GD2012-b" ; rdfs:subClassOf obo:NCBITaxon_366617 . obo:NCBITaxon_285945 a rdfs:Class ; rdfs:label "Civet SARS CoV 007/2004" ; rdfs:subClassOf obo:NCBITaxon_694009 . obo:BFO_0000029 a rdfs:Class ; rdfs:label "site"@en ; rdfs:subClassOf obo:BFO_0000004 , obo:BFO_0000141 . obo:CIDO_0000881 a rdfs:Class ; rdfs:label "SARS-CoV2 nsp4 protein binding to human TIMM10B" ; rdfs:comment "SARS-CoV2 nsp4 protein binding to human TIMM10B, as evidented by an affinity-purification mass spectrometry experiment" ; rdfs:subClassOf obo:CIDO_0000581 . obo:NCBITaxon_1146847 a rdfs:Class ; rdfs:label "Bat coronavirus M.daubentonii/UK/Wyt/962A" ; rdfs:subClassOf obo:NCBITaxon_366617 . obo:CIDO_0000304 a rdfs:Class ; rdfs:label "HCoV NL63 epitope"@en ; rdfs:subClassOf obo:CIDO_0000300 . obo:CIDO_0001041 a rdfs:Class ; rdfs:label "SARS-CoV2 orf9b protein binding to human PTBP2" ; rdfs:comment "SARS-CoV2 orf9b protein binding to human PTBP2, as evidented by an affinity-purification mass spectrometry experiment" ; rdfs:subClassOf obo:CIDO_0000052 . obo:CIDO_0001203 a rdfs:Class ; rdfs:label "SARS-CoV-2 Nucleic Acid Detection Kit (double amplification method) (WUHAN ZHONGZHI BIOTECHNOLOGIES INC.)" ; rdfs:comment """Scope of application/Intended use: Scope of application/intended use This kit is used for in vitro qualitative detection of novel coronavirus (2019-nCoV) ORF1ab in pharyngeal swabs and sputum samples of suspected novel coronavirus pneumonia cases, clustered cases, and other patients who need to be diagnosed or differentially diagnosed with novel coronavirus infection. and E gene.""" ; rdfs:subClassOf obo:CIDO_0000021 . obo:PR_O76094 a rdfs:Class ; rdfs:label "signal recognition particle subunit SRP72 (human)" ; rdfs:comment "A signal recognition particle subunit SRP72 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000015627 , obo:PR_000029067 . obo:NCBITaxon_1403206 a rdfs:Class ; rdfs:label "Coronavirus PgCoV-4" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:CIDO_0001016 a rdfs:Class ; rdfs:label "GC-376 free acid" ; rdfs:subClassOf obo:CHEBI_23367 . obo:CHEBI_60466 a rdfs:Class ; rdfs:label "peptide zwitterion" ; rdfs:comment "Zwitterionic form of any peptide where, in general, the amino terminus is positively charged and the carboxy terminus is negatively charged." ; rdfs:subClassOf obo:CHEBI_27369 . obo:GO_0060255 a rdfs:Class ; rdfs:label "regulation of macromolecule metabolic process" ; rdfs:comment "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass." ; rdfs:subClassOf obo:GO_0019222 . obo:CHEBI_25388 a rdfs:Class ; rdfs:label "monohydroxybenzoate" ; rdfs:comment "A hydroxybenzoate carrying a single hydroxy substituent at unspecified position." ; rdfs:subClassOf obo:CHEBI_24675 . obo:NCBITaxon_11120 a rdfs:Class ; rdfs:label "Infectious bronchitis virus" ; rdfs:subClassOf obo:NCBITaxon_694014 . a rdfs:Class ; rdfs:label "Dyskinesias [Disease/Finding]" ; rdfs:subClassOf , . obo:HP_0012718 a rdfs:Class ; rdfs:label "Morphological abnormality of the gastrointestinal tract" ; rdfs:comment "Abnormal structure of the gastrointestinal tract." ; rdfs:subClassOf obo:HP_0011024 , obo:HP_0025031 . obo:VO_0005413 a rdfs:Class ; rdfs:label "GEMCOVAC-19"@en ; rdfs:comment "A SARS-CoV-2 mRNA vaccine by Gennova Biopharmaceuticals Limited" ; rdfs:subClassOf obo:VO_0005198 . obo:NCBITaxon_502105 a rdfs:Class ; rdfs:label "Bovine respiratory coronavirus bovine/US/OH-440-TC/1996" ; rdfs:subClassOf obo:NCBITaxon_11128 . obo:CHEBI_35757 a rdfs:Class ; rdfs:label "monocarboxylic acid anion" ; rdfs:comment "A carboxylic acid anion formed when the carboxy group of a monocarboxylic acid is deprotonated." ; rdfs:subClassOf obo:CHEBI_29067 . obo:GO_0007267 a rdfs:Class ; rdfs:label "cell-cell signaling" ; rdfs:comment "Any process that mediates the transfer of information from one cell to another. This process includes signal transduction in the receiving cell and, where applicable, release of a ligand and any processes that actively facilitate its transport and presentation to the receiving cell. Examples include signaling via soluble ligands, via cell adhesion molecules and via gap junctions." ; rdfs:subClassOf obo:GO_0009987 , obo:GO_0023052 . obo:CHEBI_35618 a rdfs:Class ; rdfs:label "aromatic ether" ; rdfs:comment "Any ether in which the oxygen is attached to at least one aryl substituent." ; rdfs:subClassOf obo:CHEBI_25698 , obo:CHEBI_33659 . obo:HP_0000366 a rdfs:Class ; rdfs:label "Abnormality of the nose" ; rdfs:comment "An abnormality of the nose." ; rdfs:subClassOf obo:HP_0000271 . obo:PR_000003847 a rdfs:Class ; rdfs:label "angiotensinogen" ; rdfs:comment "A serpin that is a translation product of the human AGT gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000025875 . obo:CIDO_0020198 a rdfs:Class ; rdfs:label "MassARRAY SARS-CoV-2 Panel" ; rdfs:seeAlso ; rdfs:subClassOf obo:CIDO_0000454 . obo:NCBITaxon_422132 a rdfs:Class ; rdfs:label "Sambar deer coronavirus US/OH-WD388/1994" ; rdfs:subClassOf obo:NCBITaxon_11128 . obo:PR_P30530 a rdfs:Class ; rdfs:label "tyrosine-protein kinase receptor UFO (human)" ; rdfs:comment "A tyrosine-protein kinase receptor UFO that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000004528 , obo:PR_000029067 . obo:CIDO_0000020 a rdfs:Class ; rdfs:label "National Medical Products Administration"@en ; rdfs:subClassOf obo:OBI_0000245 . obo:GO_0045471 a rdfs:Class ; rdfs:label "response to ethanol" ; rdfs:comment "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ethanol stimulus." ; rdfs:subClassOf obo:GO_0097305 . obo:CIDO_0000891 a rdfs:Class ; rdfs:label "SARS-CoV2 nsp7 protein binding to human ACSL3" ; rdfs:comment "SARS-CoV2 nsp7 protein binding to human ACSL3, as evidented by an affinity-purification mass spectrometry experiment" ; rdfs:subClassOf obo:CIDO_0000049 . obo:NCBITaxon_305413 a rdfs:Class ; rdfs:label "SARS coronavirus C017" ; rdfs:subClassOf obo:NCBITaxon_694009 . obo:CHEBI_64946 a rdfs:Class ; rdfs:label "anti-HIV agent" ; rdfs:comment "An antiviral agent that destroys or inhibits the replication of the human immunodeficiency virus." ; rdfs:subClassOf obo:CHEBI_22587 . obo:CHEBI_71551 a rdfs:Class ; rdfs:label "EC 3.5.1.23 (ceramidase) inhibitor" ; rdfs:comment "An EC 3.5.1.* (non-peptide linear amide C-N hydrolase) inhibitor that interferes with the action of ceramidase (EC 3.5.1.23)." ; rdfs:subClassOf obo:CHEBI_76807 . obo:CIDO_0020282 a rdfs:Class ; rdfs:label "SARS-CoV-2 Test Kit (Real-time PCR)" ; rdfs:seeAlso ; rdfs:subClassOf obo:CIDO_0000454 . obo:GO_0048545 a rdfs:Class ; rdfs:label "response to steroid hormone" ; rdfs:comment "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a steroid hormone stimulus." ; rdfs:subClassOf obo:GO_0009725 , obo:GO_0014070 , obo:GO_0033993 . obo:GO_0010604 a rdfs:Class ; rdfs:label "positive regulation of macromolecule metabolic process" ; rdfs:comment "Any process that increases the frequency, rate or extent of the chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass." ; rdfs:subClassOf obo:GO_0009893 , obo:GO_0060255 . obo:PR_000015079 a rdfs:Class ; rdfs:label "zinc transporter 6" ; rdfs:comment "A protein that is a translation product of the human SLC30A6 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:NCBITaxon_49442 a rdfs:Class ; rdfs:label "Rhinolophus" ; rdfs:subClassOf obo:NCBITaxon_186995 . obo:PR_000029780 a rdfs:Class ; rdfs:label "tubulin beta chain" ; rdfs:comment "A tubulin that is a translation product of the human TUBB gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000028799 . obo:PR_000008481 a rdfs:Class ; rdfs:label "histone deacetylase 2" ; rdfs:comment "A protein that is a translation product of the human HDAC2 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:NCBITaxon_1788489 a rdfs:Class ; rdfs:label "Rhinolophus bat coronavirus BtCoV/3994" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:VO_0001274 a rdfs:Class ; rdfs:label "vaccine host role" ; rdfs:comment "a role of host that contains vaccine. It is a role that inheres in an organism that is the target of a vaccine administration (vaccination process)." ; rdfs:subClassOf obo:OBI_0000725 . obo:CHEBI_38161 a rdfs:Class ; rdfs:label "chelator" ; rdfs:comment "A ligand with two or more separate binding sites that can bind to a single metallic central atom, forming a chelate." ; rdfs:subClassOf obo:CHEBI_52214 . obo:GO_0043604 a rdfs:Class ; rdfs:label "amide biosynthetic process" ; rdfs:comment "The chemical reactions and pathways resulting in the formation of an amide, any derivative of an oxoacid in which an acidic hydroxy group has been replaced by an amino or substituted amino group." ; rdfs:subClassOf obo:GO_0043603 , obo:GO_0044271 . obo:NCBITaxon_389166 a rdfs:Class ; rdfs:label "Bat CoV 273/2005" ; rdfs:subClassOf obo:NCBITaxon_347537 . obo:CHEBI_24472 a rdfs:Class ; rdfs:label "halohydrocarbon" ; rdfs:comment "A compound derived from a hydrocarbon by replacing a hydrogen atom with a halogen atom." ; rdfs:subClassOf obo:CHEBI_17792 . obo:CIDO_0000321 a rdfs:Class ; rdfs:label "SNFRVQPTESIVRFP"@en ; rdfs:subClassOf obo:CIDO_0000314 . obo:CHEBI_32568 a rdfs:Class ; rdfs:label "lysine residue" ; rdfs:subClassOf obo:CHEBI_33710 . a rdfs:Class ; rdfs:label "Ergonovine [Chemical/Ingredient]" ; rdfs:subClassOf . obo:NCBITaxon_253634 a rdfs:Class ; rdfs:label "SARS coronavirus HB" ; rdfs:subClassOf obo:NCBITaxon_694009 . obo:PR_000017528 a rdfs:Class ; rdfs:label "tyrosine-protein kinase Yes" ; rdfs:comment "A proto-oncogene SRC-like tyrosine-protein kinase that is a translation product of the human YES1 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000002997 . obo:NCBITaxon_2687254 a rdfs:Class ; rdfs:label "Vespadelus regulus alphacoronavirus" ; rdfs:subClassOf obo:NCBITaxon_366617 . obo:GO_0035094 a rdfs:Class ; rdfs:label "response to nicotine" ; rdfs:comment "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nicotine stimulus." ; rdfs:subClassOf obo:GO_0042221 . obo:HP_0004364 a rdfs:Class ; rdfs:label "Abnormal circulating nitrogen compound concentration" ; rdfs:comment "Any deviation from the normal concentration of a nitrogen compound in the blood circulation." ; rdfs:subClassOf obo:HP_0032180 . a rdfs:Class ; rdfs:label "Hepatitis C, Chronic [Disease/Finding]" ; rdfs:subClassOf , . obo:DRON_00013466 a rdfs:Class ; rdfs:label "Nelfinavir" ; rdfs:subClassOf obo:OBI_0000047 . a rdfs:Class ; rdfs:label "Cyclosporins [Chemical/Ingredient]" ; rdfs:subClassOf . obo:CHEBI_38513 a rdfs:Class ; rdfs:label "indolizine alkaloid fundamental parent" ; rdfs:subClassOf obo:CHEBI_35506 . obo:PR_Q3KQU3 a rdfs:Class ; rdfs:label "MAP7 domain-containing protein 1 (human)" ; rdfs:comment "A MAP7 domain-containing protein 1 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000029067 , obo:PR_000031125 . a rdfs:Class ; rdfs:label "Propiophenones [Chemical/Ingredient]" ; rdfs:subClassOf . obo:PR_000007463 a rdfs:Class ; rdfs:label "tyrosine-protein kinase Fes/Fps" ; rdfs:comment "A protein that is a translation product of the human FES gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . a rdfs:Class ; rdfs:label "T [Preparations]" ; rdfs:subClassOf . obo:PR_000011127 a rdfs:Class ; rdfs:label "serine/threonine-protein kinase Nek11" ; rdfs:comment "A protein that is a translation product of the human NEK11 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:CIDO_0000400 a rdfs:Class ; rdfs:label "SARS-CoV-2 AY.1 virus"@en ; rdfs:subClassOf obo:CIDO_0000406 . obo:HP_0001681 a rdfs:Class ; rdfs:label "Angina pectoris" ; rdfs:comment "Paroxysmal chest pain that occurs with exertion or stress and is related to myocardial ischemia." ; rdfs:subClassOf obo:HP_0011025 . obo:CIDO_0000998 a rdfs:Class ; rdfs:label "SARS-CoV2 orf8 protein binding to human FBXL12" ; rdfs:comment "SARS-CoV2 orf8 protein binding to human FBXL12, as evidented by an affinity-purification mass spectrometry experiment" ; rdfs:subClassOf obo:CIDO_0000051 . obo:GO_0003964 a rdfs:Class ; rdfs:label "RNA-directed DNA polymerase activity" ; rdfs:comment "Catalysis of the reaction: deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1). Catalyzes RNA-template-directed extension of the 3'- end of a DNA strand by one deoxynucleotide at a time." ; rdfs:subClassOf obo:GO_0003824 . obo:NCBITaxon_1368314 a rdfs:Class ; rdfs:label "Coronavirus Neoromicia/PML-PHE1/RSA/2011" ; rdfs:subClassOf obo:NCBITaxon_1335626 . obo:CIDO_0000040 a rdf:Property ; rdfs:label "has susceptible host"@en ; rdfs:comment "An object property that represents a relation between a microbe and an organism that serves as the host role and can host the survival of the microbe." ; rdfs:range . obo:CIDO_0020048 a rdfs:Class ; rdfs:label "BioCheck SARS-CoV-2 IgG and IgM Combo Test" ; rdfs:seeAlso ; rdfs:subClassOf obo:CIDO_0000454 . obo:APOLLO_SV_00000444 a rdfs:Class ; rdfs:label "movement speed"@en ; rdfs:comment "A rate measurement datum that specifies the ratio of distance travelled during a movement process to the duration of the time interval occupied by the process."@en ; rdfs:subClassOf obo:OBI_0001554 . obo:CHEBI_37086 a rdfs:Class ; rdfs:label "C-nucleoside" ; rdfs:subClassOf obo:CHEBI_20857 . obo:PR_000006987 a rdfs:Class ; rdfs:label "eukaryotic initiation factor 4A-II" ; rdfs:comment "A protein that is a translation product of the human EIF4A2 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . a rdfs:Class ; rdfs:label "Herpes Labialis [Disease/Finding]" ; rdfs:subClassOf , . obo:NCBITaxon_2691586 a rdfs:Class ; rdfs:label "unclassified Minunacovirus" ; rdfs:subClassOf obo:NCBITaxon_2509497 . obo:GO_0050966 a rdfs:Class ; rdfs:label "detection of mechanical stimulus involved in sensory perception of pain" ; rdfs:comment "The series of events involved in the perception of pain in which a mechanical stimulus is received and converted into a molecular signal." ; rdfs:subClassOf obo:GO_0050906 , obo:GO_0050974 . obo:PR_000005587 a rdfs:Class ; rdfs:label "dual specificity protein kinase CLK4" ; rdfs:comment "A protein that is a translation product of the human CLK4 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:PR_P41240 a rdfs:Class ; rdfs:label "tyrosine-protein kinase CSK (human)" ; rdfs:comment "A tyrosine-protein kinase CSK that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000005938 , obo:PR_000029067 . obo:CHEBI_23359 a rdfs:Class ; rdfs:label "colchicine" ; rdfs:comment "An alkaloid that is a carbotricyclic compound comprising 5,6,7,9-tetrahydrobenzo[a]heptalene having four methoxy substituents at the 1-, 2-, 3- and 10-positions as well as an oxo group at the 9-position and an acetamido group at the 7-position. It has been isolated from the plants belonging to genus Colchicum." ; rdfs:subClassOf obo:CHEBI_22160 , obo:CHEBI_22315 , obo:CHEBI_35618 , obo:CHEBI_38032 . obo:CHEBI_36785 a rdfs:Class ; rdfs:label "carbobicyclic compound" ; rdfs:comment "A bicyclic compound in which all the ring atoms are carbon." ; rdfs:subClassOf obo:CHEBI_33636 , obo:CHEBI_35294 . obo:CHEBI_35236 a rdfs:Class ; rdfs:label "D-cysteine zwitterion" ; rdfs:subClassOf obo:CHEBI_35237 . obo:CIDO_0000198 a rdfs:Class ; rdfs:label "coronaviral process to host"@en ; rdfs:comment "A host-coronavirus interaction process that is implemented by the virus" ; rdfs:subClassOf obo:CIDO_0000084 , obo:OGMS_0000060 . obo:CHEBI_26986 a rdfs:Class ; rdfs:label "threonine" ; rdfs:comment "An alpha-amino acid in which one of the hydrogens attached to the alpha-carbon of glycine is substituted by a 1-hydroxyethyl group." ; rdfs:subClassOf obo:CHEBI_26167 , obo:CHEBI_38263 . a rdfs:Class ; rdfs:label "Decreased Cytokine Production [PE]" ; rdfs:subClassOf . obo:APOLLO_SV_00000174 a rdfs:Class ; rdfs:label "disease transmission model"@en ; rdfs:comment "An algorithm that models the progress of a transmissible disease in a population."@en ; rdfs:subClassOf obo:IAO_0000064 . a rdfs:Class ; rdfs:label "Amino Acid Metabolism, Inborn Errors [Disease/Finding]" ; rdfs:subClassOf . obo:DOID_14042 a rdfs:Class ; rdfs:label "bipolar I disorder" ; rdfs:comment "A bipolar disorder that is characterized by at least one manic or mixed episode." ; rdfs:subClassOf obo:DOID_3312 . obo:NCBITaxon_906886 a rdfs:Class ; rdfs:label "Feline coronavirus UU30" ; rdfs:subClassOf obo:NCBITaxon_12663 . obo:OBI_2000013 a rdfs:Class ; rdfs:label "arterial blood specimen" ; rdfs:comment "A specimen that is derived from some arterial blood" ; rdfs:subClassOf obo:OBI_2000009 . obo:NCBITaxon_1503293 a rdfs:Class ; rdfs:label "BtRf-AlphaCoV/YN2012" ; rdfs:subClassOf obo:NCBITaxon_2691594 . obo:GO_0043207 a rdfs:Class ; rdfs:label "response to external biotic stimulus" ; rdfs:comment "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an external biotic stimulus, an external stimulus caused by, or produced by living things." ; rdfs:subClassOf obo:GO_0009605 , obo:GO_0009607 . obo:CIDO_0020052 a rdfs:Class ; rdfs:label "Biocollections Worldwide SARS-Co-V-2 Assay" ; rdfs:seeAlso ; rdfs:subClassOf obo:CIDO_0000454 . obo:PR_Q8WVC6 a rdfs:Class ; rdfs:label "dephospho-CoA kinase domain-containing protein (human)" ; rdfs:comment "A dephospho-CoA kinase domain-containing protein that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000029067 , obo:PR_000029101 . obo:CHEBI_9555 a rdfs:Class ; rdfs:label "tioguanine" ; rdfs:comment "A 2-aminopurine that is the 6-thiono derivative of 2-amino-1,9-dihydro-6H-purine. Incorporates into DNA and inhibits synthesis. Used in the treatment of leukaemia." ; rdfs:subClassOf obo:CHEBI_20702 . obo:CHEBI_76655 a rdfs:Class ; rdfs:label "EC 2.1.* (C1-transferase) inhibitor" ; rdfs:comment "A transferase inhibitor inhibiting the action of transferase of a one-carbon-containing group (EC 2.1.*.*)." ; rdfs:subClassOf obo:CHEBI_71300 . obo:CIDO_0020340 a rdfs:Class ; rdfs:label "Xpert Xpress SARS-CoV-2/Flu/RSV" ; rdfs:seeAlso ; rdfs:subClassOf obo:CIDO_0000454 . obo:CIDO_0020329 a rdfs:Class ; rdfs:label "VITROS Immunodiagnostic Products Anti-SARS-CoV-2 Total Reagent Pack" ; rdfs:seeAlso ; rdfs:subClassOf obo:CIDO_0000454 . obo:CHEBI_18019 a rdfs:Class ; rdfs:label "L-lysine" ; rdfs:comment "An L-alpha-amino acid; the L-isomer of lysine." ; rdfs:subClassOf obo:CHEBI_15705 , obo:CHEBI_22658 , obo:CHEBI_25094 , obo:CHEBI_83813 . a rdfs:Class ; rdfs:label "Urogenital Neoplasms [Disease/Finding]" ; rdfs:subClassOf , , . a rdfs:Class ; rdfs:label "Elephantiasis [Disease/Finding]" ; rdfs:subClassOf . a rdfs:Class ; rdfs:label "Parasympathetic Activity Alteration [PE]" ; rdfs:subClassOf . obo:CIDO_0000310 a rdfs:Class ; rdfs:label "SLGFYNPPTNVVSHV"@en ; rdfs:subClassOf obo:CIDO_0000452 . obo:CIDO_0000810 a rdfs:Class ; rdfs:label "SARS-CoV2 nsp12 protein binding to human PPIL3" ; rdfs:comment "SARS-CoV2 nsp12 protein binding to human PPIL3, as evidented by an affinity-purification mass spectrometry experiment" ; rdfs:subClassOf obo:CIDO_0000057 . obo:NCBITaxon_745732 a rdfs:Class ; rdfs:label "Coronavirus M.das/VM105/2006/NLD" ; rdfs:subClassOf obo:NCBITaxon_696098 . obo:NCBITaxon_1643897 a rdfs:Class ; rdfs:label "Bat coronavirus ANK036F" ; rdfs:subClassOf obo:NCBITaxon_696098 . obo:NCBITaxon_681855 a rdfs:Class ; rdfs:label "Kenya bat coronavirus BtKY08" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:CHEBI_61115 a rdfs:Class ; rdfs:label "EC 3.5.1.98 (histone deacetylase) inhibitor" ; rdfs:comment "An EC 3.5.1.* (non-peptide linear amide C-N hydrolase) inhibitor that interferes with the function of histone deacetylase (EC 3.5.1.98)." ; rdfs:subClassOf obo:CHEBI_76807 . obo:CHEBI_73333 a rdfs:Class ; rdfs:label "scabicide" ; rdfs:comment "An acaricide that kills mites of the genus Sarcoptes." ; rdfs:subClassOf obo:CHEBI_22153 . obo:CHEBI_24859 a rdfs:Class ; rdfs:label "iodine atom" ; rdfs:comment "Chemical element with atomic number 53." ; rdfs:subClassOf obo:CHEBI_24473 . a rdfs:Class ; rdfs:label "Digestive System Neoplasms [Disease/Finding]" ; rdfs:subClassOf , . obo:NCBITaxon_1679882 a rdfs:Class ; rdfs:label "Coronavirus RCoV/Bor473/Rat_rat/MYS/2012" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:CIDO_0001124 a rdfs:Class ; rdfs:label "SARS-CoV2 orf8 protein binding to human NPTX1"@en ; rdfs:comment "SARS-CoV2 orf8 protein binding to human NPTX1, as evidented by an affinity-purification mass spectrometry experiment" ; rdfs:subClassOf obo:CIDO_0000051 . obo:CIDO_0000901 a rdfs:Class ; rdfs:label "SARS-CoV2 nsp7 protein binding to human HS2ST1" ; rdfs:comment "SARS-CoV2 nsp7 protein binding to human HS2ST1, as evidented by an affinity-purification mass spectrometry experiment" ; rdfs:subClassOf obo:CIDO_0000049 . obo:OBI_0000576 a rdfs:Class ; rdfs:label "scattered molecular aggregate"@en ; rdfs:comment "a material entity that consists of all the molecules of a specific type that are located in some bounded region and which is part of a more massive material entity that has parts that are other such aggregates"@en ; rdfs:subClassOf obo:BFO_0000027 , obo:BFO_0000040 . obo:PR_Q9UL54 a rdfs:Class ; rdfs:label "serine/threonine-protein kinase TAO2 (human)" ; rdfs:comment "A serine/threonine-protein kinase TAO2 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000016049 , obo:PR_000029067 . obo:CHEBI_83820 a rdfs:Class ; rdfs:label "non-proteinogenic amino acid" ; rdfs:comment "Any amino-acid that is not naturally encoded in the genetic code of any organism." ; rdfs:subClassOf obo:CHEBI_33709 . obo:PR_Q08378 a rdfs:Class ; rdfs:label "golgin subfamily A member 3 (human)" ; rdfs:comment "A golgin subfamily A member 3 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000008132 , obo:PR_000029067 . obo:NCBITaxon_413076 a rdfs:Class ; rdfs:label "Infectious bronchitis virus YEM/L-2865/2005" ; rdfs:subClassOf obo:NCBITaxon_11120 . obo:CHEBI_135714 a rdfs:Class ; rdfs:label "triparanol" ; rdfs:subClassOf obo:CHEBI_26776 . obo:NCBITaxon_11131 a rdfs:Class ; rdfs:label "Bovine coronavirus LY-138" ; rdfs:subClassOf obo:NCBITaxon_11128 . obo:CHEBI_74222 a rdfs:Class ; rdfs:label "gamma-lactam" ; rdfs:comment "A lactam in which the amide bond is contained within a five-membered ring, which includes the amide nitrogen and the carbonyl carbon." ; rdfs:subClassOf obo:CHEBI_24995 . obo:PR_Q8NFD2 a rdfs:Class ; rdfs:label "ankyrin repeat and protein kinase domain-containing protein 1 (human)" ; rdfs:comment "An ankyrin repeat and protein kinase domain-containing protein 1 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000029067 , obo:PR_000029094 . obo:VO_0005147 a rdfs:Class ; rdfs:label "SARS NDV-BC/S vaccine" ; rdfs:comment "A SARS-CoV recombinant vector vaccine that is made from the Newcastle disease virus from the mesogenic Beaudette C strainexpressing SARS-CoV S protein." ; rdfs:subClassOf obo:VO_0012183 . obo:CIDO_0020179 a rdfs:Class ; rdfs:label "KimForest SARS-CoV-2 Detection Kit v1" ; rdfs:seeAlso ; rdfs:subClassOf obo:CIDO_0000454 . obo:GO_0042060 a rdfs:Class ; rdfs:label "wound healing" ; rdfs:comment "The series of events that restore integrity to a damaged tissue, following an injury." ; rdfs:subClassOf obo:GO_0009611 . obo:PR_000009816 a rdfs:Class ; rdfs:label "LIM domain kinase 1" ; rdfs:comment "A protein that is a translation product of the human LIMK1 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:OBI_0000968 a rdfs:Class ; rdfs:label "device" ; rdfs:comment "A material entity that is designed to perform a function in a scientific investigation, but is not a reagent." ; rdfs:subClassOf obo:BFO_0000040 , obo:OBI_0000047 . obo:NCBITaxon_8287 a rdfs:Class ; rdfs:label "Sarcopterygii" ; rdfs:subClassOf obo:NCBITaxon_117571 . obo:CHEBI_83851 a rdfs:Class ; rdfs:label "1-(biphenyl-4-yloxy)-3,3-dimethyl-1-(1,2,4-triazol-1-yl)butan-2-ol" ; rdfs:comment "A member of the class of triazoles that is 3,3-dimethyl-1-(1,2,4-triazol-1-yl)butane-1,2-diol substituted at position O-1 by a biphenyl-4-yl group." ; rdfs:subClassOf obo:CHEBI_22888 , obo:CHEBI_35618 , obo:CHEBI_35681 , obo:CHEBI_35727 . obo:NCBITaxon_1897075 a rdfs:Class ; rdfs:label "Bat coronavirus Mol.ruf/63/BRA/2014" ; rdfs:subClassOf obo:NCBITaxon_366617 . obo:NCBITaxon_2042697 a rdfs:Class ; rdfs:label "SARS-related bat coronavirus RsSHC014" ; rdfs:subClassOf obo:NCBITaxon_694009 . obo:CHEBI_83565 a rdfs:Class ; rdfs:label "(trifluoromethyl)benzenes" ; rdfs:comment "An organofluorine compound that is (trifluoromethyl)benzene and derivatives arising from substitution of one or more of the phenyl hydrogens." ; rdfs:subClassOf obo:CHEBI_22712 , obo:CHEBI_37143 . obo:CIDO_0000315 a rdfs:Class ; rdfs:label "NNATNVVIKVCEFQF"@en ; rdfs:subClassOf obo:CIDO_0000314 . obo:CHEBI_58953 a rdfs:Class ; rdfs:label "saturated fatty acid anion" ; rdfs:comment "Any fatty acid anion in which there is no C-C unsaturation." ; rdfs:subClassOf obo:CHEBI_28868 . obo:CIDO_0000384 a rdfs:Class ; rdfs:label "SARS-CoV-2 Lambda variant"@en ; rdfs:subClassOf obo:CIDO_0000407 . obo:CIDO_0000167 a rdfs:Class ; rdfs:label "drug substance"@en ; rdfs:comment "A drug is a material entity that causes a change in an organism's physiology or psychology when consumed." ; rdfs:subClassOf obo:BFO_0000040 . obo:NCBITaxon_497946 a rdfs:Class ; rdfs:label "Bat coronavirus P.pyg/Germany/D5.85/2007" ; rdfs:subClassOf obo:NCBITaxon_366617 . obo:PR_P41595 a rdfs:Class ; rdfs:label "5-hydroxytryptamine receptor 2B (human)" ; rdfs:comment "A 5-hydroxytryptamine receptor 2B that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000001167 , obo:PR_000029067 . obo:CHEBI_37699 a rdfs:Class ; rdfs:label "protein kinase inhibitor" ; rdfs:comment "An EC 2.7.* (P-containing group transferase) inhibitor that interferes with the action of protein kinases." ; rdfs:subClassOf obo:CHEBI_76668 . obo:CIDO_0000912 a rdfs:Class ; rdfs:label "SARS-CoV2 nsp7 protein binding to human RAB1A" ; rdfs:comment "SARS-CoV2 nsp7 protein binding to human RAB1A, as evidented by an affinity-purification mass spectrometry experiment" ; rdfs:subClassOf obo:CIDO_0000049 . a rdfs:Class ; rdfs:label "Heart Diseases [Disease/Finding]" ; rdfs:subClassOf . obo:NCBITaxon_249089 a rdfs:Class ; rdfs:label "SARS coronavirus HZS2-Bb" ; rdfs:subClassOf obo:NCBITaxon_694009 . obo:GO_0032501 a rdfs:Class ; rdfs:label "multicellular organismal process" ; rdfs:comment "Any biological process, occurring at the level of a multicellular organism, pertinent to its function." ; rdfs:subClassOf obo:GO_0008150 . obo:CHEBI_23133 a rdfs:Class ; rdfs:label "chlorobenzoate" ; rdfs:comment "Any member of the class of benzoates in which the benzene ring is substituted by at least one chloro group." ; rdfs:subClassOf obo:CHEBI_22718 . obo:NCBITaxon_1428481 a rdfs:Class ; rdfs:label "Human coronavirus Feline-like Hu142" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:GO_0001963 a rdfs:Class ; rdfs:label "synaptic transmission, dopaminergic" ; rdfs:comment "The vesicular release of dopamine. from a presynapse, across a chemical synapse, the subsequent activation of dopamine receptors at the postsynapse of a target cell (neuron, muscle, or secretory cell) and the effects of this activation on the postsynaptic membrane potential and ionic composition of the postsynaptic cytosol. This process encompasses both spontaneous and evoked release of neurotransmitter and all parts of synaptic vesicle exocytosis. Evoked transmission starts with the arrival of an action potential at the presynapse." ; rdfs:subClassOf obo:GO_0007268 . obo:CHEBI_36683 a rdfs:Class ; rdfs:label "organochlorine compound" ; rdfs:comment "An organochlorine compound is a compound containing at least one carbon-chlorine bond." ; rdfs:subClassOf obo:CHEBI_17792 , obo:CHEBI_23117 , obo:CHEBI_36684 . obo:CHEBI_57926 a rdfs:Class ; rdfs:label "L-threonine zwitterion" ; rdfs:comment "Zwitterionic form of L-threonine arising from transfer of a proton from the carboxy to the amino group; major species at pH 7.3." ; rdfs:subClassOf obo:CHEBI_35238 . obo:NCBITaxon_903589 a rdfs:Class ; rdfs:label "Kenya bat coronavirus BtKY51" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:CHEBI_16449 a rdfs:Class ; rdfs:label "alanine" ; rdfs:comment "An alpha-amino acid that consists of propionic acid bearing an amino substituent at position 2." ; rdfs:subClassOf obo:CHEBI_33704 . obo:NCBITaxon_745735 a rdfs:Class ; rdfs:label "Coronavirus M.dau/VM222/2007/NLD" ; rdfs:subClassOf obo:NCBITaxon_696098 . obo:PR_Q9UQM7 a rdfs:Class ; rdfs:label "calcium/calmodulin-dependent protein kinase type II subunit alpha (human)" ; rdfs:comment "A calcium/calmodulin-dependent protein kinase type II subunit alpha that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000003199 , obo:PR_000029067 . obo:HP_0003124 a rdfs:Class ; rdfs:label "Hypercholesterolemia" ; rdfs:comment "An increased concentration of cholesterol in the blood." ; rdfs:subClassOf obo:HP_0003119 . a rdfs:Class ; rdfs:label "MYCOPHENOLATE MOFETIL" ; rdfs:subClassOf . obo:HP_0002813 a rdfs:Class ; rdfs:label "Abnormality of limb bone morphology" ; rdfs:comment "Any abnormality of bones of the arms or legs." ; rdfs:subClassOf obo:HP_0011844 , obo:HP_0040068 . obo:UBERON_0001159 a rdfs:Class ; rdfs:label "sigmoid colon" ; rdfs:comment "The part of the large intestine that is closest to the rectum and anus. It forms a loop that averages about 40 cm. in length, and normally lies within the pelvis, but on account of its freedom of movement it is liable to be displaced into the abdominal cavity." ; rdfs:subClassOf obo:UBERON_0000465 . a rdfs:Class ; rdfs:label "Respiratory Secretion Alteration [PE]" ; rdfs:subClassOf . a rdfs:Class ; rdfs:label "Uterine Hemorrhage [Disease/Finding]" ; rdfs:subClassOf , . obo:CHEBI_24897 a rdfs:Class ; rdfs:label "isoindoles" ; rdfs:subClassOf obo:CHEBI_22728 . obo:NCBITaxon_264372 a rdfs:Class ; rdfs:label "SARS coronavirus TW-HP2" ; rdfs:subClassOf obo:NCBITaxon_264370 . a rdfs:Class ; rdfs:label "ELTROMBOPAG" ; rdfs:subClassOf . obo:OPMI_0000417 a rdfs:Class ; rdfs:label "human patient"@en ; rdfs:comment "a human who is a recipient of a health care service performed by healthcare professionals." ; rdfs:subClassOf obo:NCBITaxon_9606 . obo:CHEBI_149484 a rdfs:Class ; rdfs:label "chloroquine(2+)" ; rdfs:comment "A quinolinium ion obtained by protonation of the quinoline nitrogen and tertiary amino group of the antimalarial drug chloroquine. It is the major species at pH 7.3." ; rdfs:subClassOf obo:CHEBI_137982 , obo:CHEBI_52837 . obo:CIDO_0001109 a rdfs:Class ; rdfs:label "SARS-CoV2 orf9b protein binding to human CHMP2A"@en ; rdfs:comment "SARS-CoV2 orf9b protein binding to human CHMP2A, as evidented by an affinity-purification mass spectrometry experiment" ; rdfs:subClassOf obo:CIDO_0000052 . obo:NCBITaxon_267397 a rdfs:Class ; rdfs:label "SARS coronavirus Sin847" ; rdfs:subClassOf obo:NCBITaxon_694009 . obo:CHEBI_32837 a rdfs:Class ; rdfs:label "L-serinium" ; rdfs:comment "A serinium that is the conjugate acid of L-serine, obtained by protonation of the amino group." ; rdfs:subClassOf obo:CHEBI_32846 . obo:PR_Q02779 a rdfs:Class ; rdfs:label "mitogen-activated protein kinase kinase kinase 10 (human)" ; rdfs:comment "A mitogen-activated protein kinase kinase kinase 10 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000010129 , obo:PR_000029067 . obo:GO_0071407 a rdfs:Class ; rdfs:label "cellular response to organic cyclic compound" ; rdfs:comment "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an organic cyclic compound stimulus." ; rdfs:subClassOf obo:GO_0014070 , obo:GO_0071310 . obo:CHEBI_26273 a rdfs:Class ; rdfs:label "proline derivative" ; rdfs:comment "An amino acid derivative resulting from reaction of proline at the amino group or the carboxy group, or from the replacement of any hydrogen of proline by a heteroatom. The definition normally excludes peptides containing proline residues." ; rdfs:subClassOf obo:CHEBI_83821 . obo:VO_0001055 a rdfs:Class ; rdfs:label "chimpanzee adenovirus vaccine vector"@en ; rdfs:comment "an adenovirus vaccine vector that uses a chimpanzee adenovirus strain" ; rdfs:subClassOf obo:VO_0000136 . obo:CHEBI_36902 a rdfs:Class ; rdfs:label "chalcogen hydride" ; rdfs:subClassOf obo:CHEBI_33242 , obo:CHEBI_33304 . obo:PR_000005347 a rdfs:Class ; rdfs:label "centrosome-associated protein CEP250" ; rdfs:comment "A protein that is a translation product of the human CEP250 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:CHEBI_35727 a rdfs:Class ; rdfs:label "triazoles" ; rdfs:comment "An azole in which the five-membered heterocyclic aromatic skeleton contains three N atoms and two C atoms." ; rdfs:subClassOf obo:CHEBI_25693 , obo:CHEBI_38101 , obo:CHEBI_68452 . obo:OBI_0002523 a rdfs:Class ; rdfs:label "breast specimen" ; rdfs:comment "A specimen that is derived from breast. " ; rdfs:subClassOf obo:OBI_0001479 . obo:CIDO_0000496 a rdfs:Class ; rdfs:label "FAVESGGYIPSDFAF" ; rdfs:comment "A coronavirus epitope that is part of some S protein from HCoV 229E composed of the following amino acids FAVESGGYIPSDFAF" ; rdfs:subClassOf obo:CIDO_0000451 . obo:NCBITaxon_1532169 a rdfs:Class ; rdfs:label "Alphacoronavirus BtCoV/GrNC6/Neo_cap/RSA/2012" ; rdfs:subClassOf obo:NCBITaxon_366617 . obo:CIDO_0020224 a rdfs:Class ; rdfs:label "OraRisk COVID-19 RT-PCR" ; rdfs:seeAlso ; rdfs:subClassOf obo:CIDO_0000454 . a rdfs:Class ; rdfs:label "Ileal Neoplasms [Disease/Finding]" ; rdfs:subClassOf , . obo:NCBITaxon_240550 a rdfs:Class ; rdfs:label "SARS coronavirus TWJ" ; rdfs:subClassOf obo:NCBITaxon_694009 . obo:PR_000030353 a rdfs:Class ; rdfs:label "protein FAM162A" ; rdfs:comment "A protein that is a translation product of the human FAM162A gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:NCBITaxon_231520 a rdfs:Class ; rdfs:label "SARS coronavirus HKU-65806" ; rdfs:subClassOf obo:NCBITaxon_694009 . obo:CIDO_0000560 a rdfs:Class ; rdfs:label "VVGGTIQILASVPEK" ; rdfs:comment "A coronavirus epitope that is part of some S protein from HCoV 229E composed of the following amino acids VVGGTIQILASVPEK" ; rdfs:subClassOf obo:CIDO_0000451 . obo:NCBITaxon_389249 a rdfs:Class ; rdfs:label "Bat coronavirus (BtCoV/A421/2005)" ; rdfs:subClassOf obo:NCBITaxon_389126 . obo:NCBITaxon_1699319 a rdfs:Class ; rdfs:label "Myotis Bat Alphacoronavirus strain MJ_2C" ; rdfs:subClassOf obo:NCBITaxon_366617 . obo:DOID_0070083 a rdfs:Class ; rdfs:label "schizophrenia 7" ; rdfs:comment "A schizophrenia that has_material_basis_in an autosomal dominant mutation of SCZD7 on chromosome 13q32." ; rdfs:subClassOf obo:DOID_0050736 , obo:DOID_5419 . a rdfs:Class ; rdfs:label "17-alpha-hydroxy-progesterone caproate [Chemical/Ingredient]" ; rdfs:subClassOf . a rdfs:Class ; rdfs:label "Arbovirus Infections [Disease/Finding]" ; rdfs:subClassOf obo:DOID_934 . obo:CIDO_0000636 a rdfs:Class ; rdfs:label "I2230T in SARS-CoV-2 pp1a protein" ; rdfs:comment "An AA variant that has mutated an amino acid at position 2230 into a threonine" ; rdfs:subClassOf obo:CIDO_0001074 . obo:CIDO_0020311 a rdfs:Class ; rdfs:label "UBI SARS-CoV-2 ELISA" ; rdfs:seeAlso ; rdfs:subClassOf obo:CIDO_0000454 . obo:CHEBI_76871 a rdfs:Class ; rdfs:label "EC 2.1.1.* (methyltransferases) inhibitor" ; rdfs:comment "An EC 2.1.* (C1-transferase) inhibitor that interferes with the action of any methyltransferase (EC 2.1.1.*)." ; rdfs:subClassOf obo:CHEBI_76655 . obo:PR_Q9Y2H9 a rdfs:Class ; rdfs:label "microtubule-associated serine/threonine-protein kinase 1 (human)" ; rdfs:comment "A microtubule-associated serine/threonine-protein kinase 1 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000010195 , obo:PR_000029067 . a rdfs:Class ; rdfs:label "Metabolic Rate Alteration [PE]" ; rdfs:subClassOf . obo:CHEBI_23252 a rdfs:Class ; rdfs:label "cinnamic acids" ; rdfs:comment "Any alpha,beta-unsaturated monocarboxylic acid based on the cinnamic acid skeleton and its substituted derivatives." ; rdfs:subClassOf obo:CHEBI_78840 , obo:CHEBI_79020 . obo:CHEBI_32876 a rdfs:Class ; rdfs:label "tertiary amine" ; rdfs:comment "A compound formally derived from ammonia by replacing three hydrogen atoms by hydrocarbyl groups." ; rdfs:subClassOf obo:CHEBI_32952 , obo:CHEBI_50996 . obo:CHEBI_24471 a rdfs:Class ; rdfs:label "halogen molecular entity" ; rdfs:subClassOf obo:CHEBI_33675 . obo:CHEBI_57844 a rdfs:Class ; rdfs:label "L-methionine zwitterion" ; rdfs:comment "Zwitterionic form of L-methionine having a anionic carboxy group and a cationic amino group; major species at pH 7.3." ; rdfs:subClassOf obo:CHEBI_64558 . obo:CHEBI_39447 a rdfs:Class ; rdfs:label "pyrimidines" ; rdfs:comment "Any compound having a pyrimidine as part of its structure." ; rdfs:subClassOf obo:CHEBI_38313 . obo:CHEBI_50330 a rdfs:Class ; rdfs:label "2-amino-2-oxoethyl group" ; rdfs:subClassOf obo:CHEBI_50325 . obo:CIDO_0000280 a rdfs:Class ; rdfs:label "viral life cycle - obsolete"@en ; rdfs:comment "Note: this term is obsolete because a term with the same name has been imported from GO and used." ; rdfs:subClassOf obo:CIDO_0000409 . obo:VO_0005259 a rdfs:Class ; rdfs:label "COVID-19 rNDV vector vaccine by Laboratorio Avi-Mex"@en ; rdfs:comment "A recombinant Newcastle Disease Virus vectored vaccine for SARS-CoV-2 by Laboratorio Avi-Mex" ; rdfs:subClassOf obo:VO_0005199 . obo:OPMI_0000507 a rdfs:Class ; rdfs:label "procedure temporal region"@en ; rdfs:comment "A temporal region that is associated with a procedure" ; rdfs:subClassOf obo:BFO_0000148 . obo:CHEBI_37335 a rdfs:Class ; rdfs:label "MRI contrast agent" ; rdfs:subClassOf obo:CHEBI_37334 . obo:CIDO_0000800 a rdfs:Class ; rdfs:label "SARS-CoV2 nsp10 protein binding to human GFER" ; rdfs:comment "SARS-CoV2 nsp10 protein binding to human GFER, as evidented by an affinity-purification mass spectrometry experiment" ; rdfs:subClassOf obo:CIDO_0000064 . obo:CIDO_0000382 a rdfs:Class ; rdfs:label "SARS-CoV-2 Iota variant"@en ; rdfs:subClassOf obo:CIDO_0000234 , obo:CIDO_0000407 . obo:NCBITaxon_742001 a rdfs:Class ; rdfs:label "Bat SARS coronavirus HKU3-4" ; rdfs:subClassOf obo:NCBITaxon_442736 . obo:CIDO_0000728 a rdfs:Class ; rdfs:label "E484Q in SARS-CoV-2 S protein"@en ; rdfs:comment "An AA mutation or AA variant that has mutated an amino acid at position 484 into glutamine in S protein." ; rdfs:subClassOf obo:CIDO_0000593 . obo:GO_0050789 a rdfs:Class ; rdfs:label "regulation of biological process" ; rdfs:comment "Any process that modulates the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule." ; rdfs:subClassOf obo:GO_0065007 . obo:CHEBI_50268 a rdfs:Class ; rdfs:label "GABA modulator" ; rdfs:comment "A substance that does not act as agonist or antagonist but does affect the gamma-aminobutyric acid receptor-ionophore complex. GABA-A receptors appear to have at least three allosteric sites at which modulators act: a site at which benzodiazepines act by increasing the opening frequency of gamma-aminobutyric acid-activated chloride channels; a site at which barbiturates act to prolong the duration of channel opening; and a site at which some steroids may act." ; rdfs:subClassOf obo:CHEBI_38632 , obo:CHEBI_51374 . obo:GO_0042592 a rdfs:Class ; rdfs:label "homeostatic process" ; rdfs:comment "Any biological process involved in the maintenance of an internal steady state." ; rdfs:subClassOf obo:GO_0065008 . obo:CIDO_0000501 a rdfs:Class ; rdfs:label "GAISSSLQEILSRLD" ; rdfs:comment "A coronavirus epitope that is part of some S protein from HCoV HKU1 composed of the following amino acids GAISSSLQEILSRLD" ; rdfs:subClassOf obo:CIDO_0000409 . obo:PR_000050283 a rdfs:Class ; rdfs:label "ORF1ab proteolytic cleavage product (SARS-CoV-2)" ; rdfs:comment "A replicase polyprotein 1ab (SARS-CoV-2) that has been processed by proteolytic cleavage." ; rdfs:subClassOf obo:PR_P0DTD1-1 . obo:PR_Q9UDR5 a rdfs:Class ; rdfs:label "alpha-aminoadipic semialdehyde synthase, mitochondrial (human)" ; rdfs:comment "An alpha-aminoadipic semialdehyde synthase, mitochondrial that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000003532 , obo:PR_000029067 . obo:OAE_0000645 a rdfs:Class ; rdfs:label "erythema AE" ; rdfs:comment "Erythema AE is a skin adverse event that showns redness of the skin caused by hyperemia of the capillaries in the lower layers of the skin." ; rdfs:subClassOf obo:OAE_0000543 . obo:PR_P51843 a rdfs:Class ; rdfs:label "nuclear receptor subfamily 0 group B member 1 (human)" ; rdfs:comment "A nuclear receptor subfamily 0 group B member 1 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000011390 , obo:PR_000029067 . obo:PR_Q05586 a rdfs:Class ; rdfs:label "glutamate receptor ionotropic, NMDA 1 (human)" ; rdfs:comment "A glutamate receptor ionotropic, NMDA 1 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000008245 , obo:PR_000029067 . obo:OBI_2000016 a rdfs:Class ; rdfs:label "erythrocyte specimen" ; rdfs:comment "A specimen that is derived from some erythrocytes" ; rdfs:subClassOf obo:OBI_0002599 . obo:PR_P14735 a rdfs:Class ; rdfs:label "insulin-degrading enzyme (human)" ; rdfs:comment "An insulin-degrading enzyme that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000008886 , obo:PR_000029067 . obo:CHEBI_132992 a rdfs:Class ; rdfs:label "radiosensitizing agent" ; rdfs:comment "A drug that makes increases the sensitivity of tumour cells to radiation therapy." ; rdfs:subClassOf obo:CHEBI_23888 . obo:CHEBI_33958 a rdfs:Class ; rdfs:label "halide salt" ; rdfs:subClassOf obo:CHEBI_24866 , obo:CHEBI_37578 . obo:CHEBI_109969 a rdfs:Class ; rdfs:label "2-fluoro-N-[[(2S,3S)-5-[(2R)-1-hydroxypropan-2-yl]-3-methyl-6-oxo-8-phenyl-3,4-dihydro-2H-pyrido[2,3-b][1,5]oxazocin-2-yl]methyl]-N-methylbenzamide" ; rdfs:subClassOf obo:CHEBI_38193 . obo:CHEBI_26144 a rdfs:Class ; rdfs:label "piperazines" ; rdfs:subClassOf obo:CHEBI_25693 , obo:CHEBI_38101 . obo:CIDO_0000798 a rdfs:Class ; rdfs:label "SARS-CoV2 nsp10 protein binding to human AP2M1" ; rdfs:comment "SARS-CoV2 nsp10 protein binding to human AP2M1, as evidented by an affinity-purification mass spectrometry experiment" ; rdfs:subClassOf obo:CIDO_0000064 . obo:PR_000029363 a rdfs:Class ; rdfs:label "centriolin" ; rdfs:comment "A protein that is a translation product of the human CNTRL gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:PR_Q9BU02 a rdfs:Class ; rdfs:label "thiamine-triphosphatase (human)" ; rdfs:comment "A thiamine-triphosphatase that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000016324 , obo:PR_000029067 . obo:VO_0005153 a rdfs:Class ; rdfs:label "AdCOVID"@en ; rdfs:comment "A SARS-CoV-2 single dose intranasal vaccine manufactured by Altimmune in collaboration with the University of Alabama-Birmingham. This vaccine was discontinued after a Phase 1 trial." ; rdfs:subClassOf obo:VO_0005200 . a rdfs:Class ; rdfs:label "I [Preparations]" ; rdfs:subClassOf . obo:CIDO_0001052 a rdfs:Class ; rdfs:label "SARS-CoV2 orf9c protein binding to human FAR2" ; rdfs:comment "SARS-CoV2 orf9c protein binding to human FAR2, as evidented by an affinity-purification mass spectrometry experiment" ; rdfs:subClassOf obo:CIDO_0000054 . obo:PR_000001098 a rdfs:Class ; rdfs:label "5-hydroxytryptamine receptor 1" ; rdfs:comment "A 5-hydroxytryptamine receptor that is a translation product of the human HTR1A, HTR1B, HTR1D, HTR1E or HTR1F genes, 1:1 orthologs thereof, or a semi-ortholog thereof. The preferred ligand is 5-hydroxytryptamine (serotonin)." ; rdfs:subClassOf obo:PR_000044625 . a rdfs:Class ; rdfs:label "Pericarditis [Disease/Finding]" ; rdfs:subClassOf . a rdfs:Class ; rdfs:label "Gonadal Steroid Hormones [Chemical/Ingredient]" ; rdfs:subClassOf . obo:PR_000001448 a rdfs:Class ; rdfs:label "fibroblast growth factor receptor 1" ; rdfs:comment "A fibroblast growth factor receptor that is a translation product of the human FGFR1 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000001349 . a rdfs:Class ; rdfs:label "PHENAZOPYRIDINE" ; rdfs:subClassOf . a rdfs:Class ; rdfs:label "Decreased DNA Integrity [PE]" ; rdfs:subClassOf . obo:CIDO_0000671 a rdfs:Class ; rdfs:label "G446S in SARS-CoV-2 S protein" ; rdfs:comment "An AA mutation or AA variant that has mutated an amino acid at position 446 into a serine in S protein." ; rdfs:subClassOf obo:CIDO_0000593 . obo:CHEBI_50177 a rdfs:Class ; rdfs:label "dermatologic drug" ; rdfs:comment "A drug used to treat or prevent skin disorders or for the routine care of skin." ; rdfs:subClassOf obo:CHEBI_23888 . obo:UBERON_0000004 a rdfs:Class ; rdfs:label "nose" ; rdfs:comment "The olfactory organ of vertebrates, consisting of nares, olfactory epithelia and the structures and skeletal framework of the nasal cavity." ; rdfs:subClassOf obo:UBERON_0000061 , obo:UBERON_0000062 , obo:UBERON_0004121 , obo:UBERON_0010000 , obo:UBERON_0010314 . obo:OPMI_0000575 a rdfs:Class ; rdfs:label "observation period"@en ; rdfs:comment "A period time when an observation is conducted." ; rdfs:subClassOf obo:BFO_0000038 , obo:OPMI_0000576 . obo:PR_P38631 a rdfs:Class ; rdfs:label "1,3-beta-glucan synthase component FKS1 (yeast)" ; rdfs:comment "A protein that is a translation product of the FKS1 gene in yeast." ; rdfs:subClassOf obo:PR_000029055 . obo:CHEBI_29412 a rdfs:Class ; rdfs:label "oxonium" ; rdfs:subClassOf obo:CHEBI_33693 , obo:CHEBI_50313 . a rdfs:Class ; rdfs:label "Myocardial Infarction [Disease/Finding]" ; rdfs:subClassOf . obo:GO_1901698 a rdfs:Class ; rdfs:label "response to nitrogen compound" ; rdfs:comment "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nitrogen compound stimulus." ; rdfs:subClassOf obo:GO_0042221 . obo:CHEBI_32440 a rdfs:Class ; rdfs:label "alaninium" ; rdfs:comment "An alpha-amino-acid cation that is the conjugate acid of alanine." ; rdfs:subClassOf obo:CHEBI_33719 . obo:NCBITaxon_2042570 a rdfs:Class ; rdfs:label "Coronavirus PREDICT CoV-44" ; rdfs:subClassOf obo:NCBITaxon_696098 . obo:NCBITaxon_749426 a rdfs:Class ; rdfs:label "Glaucous-winged gull CIR-66002" ; rdfs:subClassOf obo:NCBITaxon_749416 . obo:CHEBI_8378 a rdfs:Class ; rdfs:label "prednisolone" ; rdfs:comment "A glucocorticoid that is prednisone in which the oxo group at position 11 has been reduced to the corresponding beta-hydroxy group. It is a drug metabolite of prednisone." ; rdfs:subClassOf obo:CHEBI_139590 , obo:CHEBI_139592 , obo:CHEBI_24261 , obo:CHEBI_35342 , obo:CHEBI_35344 , obo:CHEBI_35346 , obo:CHEBI_36885 , obo:CHEBI_61313 , obo:CHEBI_77166 . a rdfs:Class ; rdfs:label "Lymphoproliferative Disorders [Disease/Finding]" ; rdfs:subClassOf , . obo:CIDO_0000664 a rdfs:Class ; rdfs:label "D80A in SARS-CoV-2 S protein" ; rdfs:comment "An AA mutation or AA variant that has mutated an amino acid at position 80 into a alanine in S protein." ; rdfs:subClassOf obo:CIDO_0000594 . obo:PR_000005903 a rdfs:Class ; rdfs:label "CREB-regulated transcription coactivator 3" ; rdfs:comment "A protein that is a translation product of the human CRTC3 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:CIDO_0000449 a rdfs:Class ; rdfs:label "HCoV NL63 S protein epitope"@en ; rdfs:subClassOf obo:CIDO_0000409 . obo:OBI_0002123 a rdfs:Class ; rdfs:label "IHC slide staining"@en ; rdfs:comment "A staining using labeled antibodies, i.e. the analytical part of immunohistochemistry. The staining is applied to fixed specimens on slides to identify biomarkers in tissues."@en ; rdfs:subClassOf obo:OBI_0302887 . obo:CHEBI_26766 a rdfs:Class ; rdfs:label "steroid lactone" ; rdfs:subClassOf obo:CHEBI_25000 , obo:CHEBI_35341 . obo:NCBITaxon_941326 a rdfs:Class ; rdfs:label "unclassified Mus" ; rdfs:subClassOf obo:NCBITaxon_10088 . a rdfs:Class ; rdfs:label "Respiratory Syncytial Virus Infections [Disease/Finding]" ; rdfs:subClassOf . obo:CIDO_0000081 a rdfs:Class ; rdfs:label "chemical role modulating host immune response to SARS-CoV-2 infection"@en ; rdfs:comment "A role of a chemical effective in modulating host response to SARS-CoV-2 infection" ; rdfs:subClassOf obo:CIDO_0000080 . a rdfs:Class ; rdfs:label "Positive Chronotropy [PE]" ; rdfs:subClassOf . obo:CIDO_0020205 a rdfs:Class ; rdfs:label "MiraDx SARS-CoV-2 RT-PCR assay" ; rdfs:seeAlso ; rdfs:subClassOf obo:CIDO_0000454 . obo:CHEBI_27096 a rdfs:Class ; rdfs:label "trichlorobenzene" ; rdfs:comment "Any member of the class of chlorobenzenes carrying three chloro substituents at unspecified positions." ; rdfs:subClassOf obo:CHEBI_23132 . obo:GO_0002684 a rdfs:Class ; rdfs:label "positive regulation of immune system process" ; rdfs:comment "Any process that activates or increases the frequency, rate, or extent of an immune system process." ; rdfs:subClassOf obo:GO_0002682 , obo:GO_0048518 . obo:PR_Q99720 a rdfs:Class ; rdfs:label "sigma non-opioid intracellular receptor 1 (human)" ; rdfs:comment "A sigma non-opioid intracellular receptor 1 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000011650 , obo:PR_000029067 . obo:CHEBI_48706 a rdfs:Class ; rdfs:label "antagonist" ; rdfs:comment "Substance that attaches to and blocks cell receptors that normally bind naturally occurring substances." ; rdfs:subClassOf obo:CHEBI_52210 . obo:CIDO_0001023 a rdfs:Class ; rdfs:label "Goflikicept" ; rdfs:subClassOf obo:CHEBI_23367 . obo:VO_0005090 a rdfs:Class ; rdfs:label "IIBR-100"@en ; rdfs:comment "A rVSV-SARS-CoV-2-S vaccine developed by the Israel Institute for Biological Research (IIBR)" ; rdfs:subClassOf obo:VO_0005199 . obo:PR_000016241 a rdfs:Class ; rdfs:label "dual specificity testis-specific protein kinase 1" ; rdfs:comment "A protein that is a translation product of the human TESK1 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . a rdfs:Class ; rdfs:label "Gonadal Disorders [Disease/Finding]" ; rdfs:subClassOf . obo:PR_Q15370 a rdfs:Class ; rdfs:label "elongin-B (human)" ; rdfs:comment "An elongin-B that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000016169 , obo:PR_000029067 . obo:CHEBI_25830 a rdfs:Class ; rdfs:label "p-quinones" ; rdfs:comment "A quinone in which the two oxo groups of the quinone are located para to each other on the 6-membered quinonoid ring." ; rdfs:subClassOf obo:CHEBI_36141 . obo:GO_0019815 a rdfs:Class ; rdfs:label "B cell receptor complex" ; rdfs:comment "An immunoglobulin complex that is present in the plasma membrane of B cells and that in its canonical form is composed of two identical immunoglobulin heavy chains and two identical immunoglobulin light chains and a signaling subunit, a heterodimer of the Ig-alpha and Ig-beta proteins." ; rdfs:subClassOf obo:OBI_1110022 . obo:PR_Q8TD08 a rdfs:Class ; rdfs:label "mitogen-activated protein kinase 15 (human)" ; rdfs:comment "A mitogen-activated protein kinase 15 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000010155 , obo:PR_000029067 . obo:CHEBI_37963 a rdfs:Class ; rdfs:label "pyranone" ; rdfs:comment "Any of a class of cyclic chemical compounds that contain an unsaturated six-membered ring with one ring oxygen atom and an oxo substituent." ; rdfs:subClassOf obo:CHEBI_26407 . obo:CHEBI_30823 a rdfs:Class ; rdfs:label "oleate" ; rdfs:comment "A C18, long straight-chain monounsaturated fatty acid anion; and the conjugate base of oleic acid, arising from deprotonation of the carboxylic acid group." ; rdfs:subClassOf obo:CHEBI_132944 . obo:NCBITaxon_291613 a rdfs:Class ; rdfs:label "SARS coronavirus GD322" ; rdfs:subClassOf obo:NCBITaxon_694009 . obo:CIDO_0000528 a rdfs:Class ; rdfs:label "LLLWESGKAKPPLNR" ; rdfs:comment "A coronavirus epitope that is part of some S protein from HCoV 229E composed of the following amino acids LLLWESGKAKPPLNR" ; rdfs:subClassOf obo:CIDO_0000451 . obo:PR_000031965 a rdfs:Class ; rdfs:label "endoplasmic reticulum lectin 1" ; rdfs:comment "A protein that is a translation product of the human ERLEC1 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:PR_Q03393 a rdfs:Class ; rdfs:label "6-pyruvoyl tetrahydrobiopterin synthase (human)" ; rdfs:comment "A 6-pyruvoyl tetrahydrobiopterin synthase that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000013485 , obo:PR_000029067 . obo:CHEBI_36586 a rdfs:Class ; rdfs:label "carbonyl compound" ; rdfs:comment "Any compound containing the carbonyl group, C=O. The term is commonly used in the restricted sense of aldehydes and ketones, although it actually includes carboxylic acids and derivatives." ; rdfs:subClassOf obo:CHEBI_36587 , obo:CHEBI_36963 . obo:CHEBI_33280 a rdfs:Class ; rdfs:label "molecular messenger" ; rdfs:subClassOf obo:CHEBI_24432 . obo:CIDO_0000717 a rdfs:Class ; rdfs:label "L3468V in SARS-CoV-2 pp1a protein"@en ; rdfs:comment "An AA mutation or AA variant that has mutated an amino acid at position 3468 into a valine in pp1a." ; rdfs:subClassOf obo:CIDO_0001076 . obo:NCBITaxon_441978 a rdfs:Class ; rdfs:label "Chinese ferret badger coronavirus Guangxi/F247/2006" ; rdfs:subClassOf obo:NCBITaxon_441985 . obo:CHEBI_32579 a rdfs:Class ; rdfs:label "lysinium residue" ; rdfs:subClassOf obo:CHEBI_35415 . a rdfs:Class ; rdfs:label "AZITHROMYCIN" ; rdfs:subClassOf . a rdfs:Class ; rdfs:label "PENCICLOVIR" ; rdfs:subClassOf . obo:NCBITaxon_2042592 a rdfs:Class ; rdfs:label "Coronavirus PREDICT CoV-68" ; rdfs:subClassOf obo:NCBITaxon_696098 . obo:HP_0005743 a rdfs:Class ; rdfs:label "Avascular necrosis of the capital femoral epiphysis" ; rdfs:comment "Avascular necrosis of the proximal epiphysis of the femur occurring in growing children and caused by an interruption of the blood supply to the head of the femur close to the hip joint. The necrosis is characteristically associated with flattening of the femoral head, for which reason the term coxa plana has been used to refer to this feature in the medical literature." ; rdfs:subClassOf obo:HP_0010574 , obo:HP_0011843 . obo:NCBITaxon_1503279 a rdfs:Class ; rdfs:label "BtMf-AlphaCoV/FJ2012" ; rdfs:subClassOf obo:NCBITaxon_694001 . obo:NCBITaxon_2042549 a rdfs:Class ; rdfs:label "Coronavirus PREDICT CoV-22" ; rdfs:subClassOf obo:NCBITaxon_696098 . obo:PR_000007299 a rdfs:Class ; rdfs:label "prothrombin" ; rdfs:comment "A protein that is a translation product of the human F2 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:NCBITaxon_903634 a rdfs:Class ; rdfs:label "Kenya bat coronavirus BtKY96" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:PR_P05129 a rdfs:Class ; rdfs:label "protein kinase C gamma type (human)" ; rdfs:comment "A protein kinase C gamma type that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000003060 , obo:PR_000029067 . obo:DRON_00023321 a rdfs:Class ; rdfs:label "Ritonavir Oral Capsule" ; rdfs:subClassOf obo:DRON_00000026 . obo:CIDO_0000133 a rdf:Property ; rdfs:label "drug has protein target as activator"@en ; rdfs:comment "An object property that represents a relation between a drug and a protein where the drug can target the protein as an enzyme activator.An enzyme inducer is a type of drug or chemcial that increases the metabolic activity of an enzyme either by binding to the enzyme and activating it, or by increasing the expression of the gene coding for the enzyme." ; rdfs:range ; rdfs:subPropertyOf obo:CIDO_0000124 . obo:CIDO_0000175 a rdf:Property ; rdfs:label "drug effective in vivo against virus"@en ; rdfs:comment "An object property that represents a relation between a chemical entity and a virus where the chemical has an effective role against viral infection in vivo" ; rdfs:range ; rdfs:subPropertyOf obo:CIDO_0000174 . obo:CHEBI_50525 a rdfs:Class ; rdfs:label "phenolate anion" ; rdfs:comment "An organic anion arising from deprotonation of the OH function of a phenol compound." ; rdfs:subClassOf obo:CHEBI_25696 . obo:OAE_0000001 a rdfs:Class ; rdfs:label "adverse event" ; rdfs:comment "a pathological bodily process that occurs after a medical intervention. An adverse event is likely caused by the medical intervention; however, such a causal association is not required to be an adverse event." ; rdfs:subClassOf obo:OGMS_0000061 . obo:CHEBI_32822 a rdfs:Class ; rdfs:label "L-threoninium" ; rdfs:comment "The L-enantiomer of threoninium." ; rdfs:subClassOf obo:CHEBI_32833 . obo:PR_000013286 a rdfs:Class ; rdfs:label "serine/threonine-protein kinase PRP4" ; rdfs:comment "A protein that is a translation product of the human PRPF4B gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:PR_000001293 a rdfs:Class ; rdfs:label "C-type lectin domain family 4 member K" ; rdfs:comment "A protein that is a translation product of the human CD207 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:PR_000001445 a rdfs:Class ; rdfs:label "discoidin domain-containing receptor 1" ; rdfs:comment "A discoidin domain-containing receptor that is a translation product of the human DDR1 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000001342 . a rdfs:Class ; rdfs:label "Leukemia, Myeloid, Accelerated Phase [Disease/Finding]" ; rdfs:subClassOf . obo:PR_000014193 a rdfs:Class ; rdfs:label "60S ribosomal protein L13a" ; rdfs:comment "A protein that is a translation product of the human RPL13A gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:OBI_0002501 a rdfs:Class ; rdfs:label "bile specimen" ; rdfs:comment "A specimen that is derived from bile." ; rdfs:subClassOf obo:OBI_2000009 . obo:PR_000013427 a rdfs:Class ; rdfs:label "prostaglandin G/H synthase 1" ; rdfs:comment "A protein that is a translation product of the human PTGS1 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:NCBITaxon_2716128 a rdfs:Class ; rdfs:label "Bottlenose dolphin coronavirus" ; rdfs:subClassOf obo:NCBITaxon_2724084 . a rdfs:Class ; rdfs:label "Anemia [Disease/Finding]" ; rdfs:subClassOf . obo:CIDO_0020269 a rdfs:Class ; rdfs:label "SARS-Cov-2 Assay" ; rdfs:seeAlso ; rdfs:subClassOf obo:CIDO_0000454 . obo:PR_000003009 a rdfs:Class ; rdfs:label "radixin" ; rdfs:comment "An erm protein that is a translation product of the human RDX gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000001030 . obo:PR_P0DTC7 a rdfs:Class ; rdfs:label "ORF7a protein (SARS-CoV-2)" ; rdfs:comment "A protein that is a translation product of the ORF7a gene in SARS-CoV-2." ; rdfs:subClassOf obo:PR_000050262 . obo:OBI_0000965 a rdfs:Class ; rdfs:label "lyophilized specimen" ; rdfs:comment "a specimen that is output of a lyophilization storage process in which specimen is lyophilized for storage." ; rdfs:subClassOf obo:OBI_0001472 . obo:UBERON_0005181 a rdfs:Class ; rdfs:label "thoracic segment organ" ; rdfs:comment "An organ that part of the thoracic segment region. This region can be further subdividied chest and thoracic cavity regions." ; rdfs:subClassOf obo:UBERON_0005177 . obo:CIDO_0000862 a rdfs:Class ; rdfs:label "SARS-CoV2 nsp13 protein binding to human USP13" ; rdfs:comment "SARS-CoV2 nsp13 protein binding to human USP13, as evidented by an affinity-purification mass spectrometry experiment" ; rdfs:subClassOf obo:CIDO_0000058 . obo:CHEBI_33575 a rdfs:Class ; rdfs:label "carboxylic acid" ; rdfs:comment "A carbon oxoacid acid carrying at least one -C(=O)OH group and having the structure RC(=O)OH, where R is any any monovalent functional group. Carboxylic acids are the most common type of organic acid." ; rdfs:subClassOf obo:CHEBI_24833 , obo:CHEBI_35605 , obo:CHEBI_36586 , obo:CHEBI_50860 , obo:CHEBI_64709 . obo:PR_000001709 a rdfs:Class ; rdfs:label "sphingosine 1-phosphate receptor 4" ; rdfs:comment "A lysophospholipid (S1P) receptor that is a translation product of the human S1PR4 gene or a 1:1 ortholog thereof. This receptor is specifically expressed in fetal and adult lymphoid and hematopoietic tissue as well as in lung." ; rdfs:subClassOf obo:PR_000001673 . obo:CHEBI_60832 a rdfs:Class ; rdfs:label "tubulin modulator" ; rdfs:comment "Any substance that interacts with tubulin to inhibit or promote polymerisation of microtubules." ; rdfs:subClassOf obo:CHEBI_52210 . obo:NCBITaxon_258963 a rdfs:Class ; rdfs:label "SARS coronavirus TW10" ; rdfs:subClassOf obo:NCBITaxon_694009 . obo:PR_Q9BVS4 a rdfs:Class ; rdfs:label "serine/threonine-protein kinase RIO2 (human)" ; rdfs:comment "A serine/threonine-protein kinase RIO2 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000014020 , obo:PR_000029067 . obo:PR_O14521 a rdfs:Class ; rdfs:label "succinate dehydrogenase [ubiquinone] cytochrome b small subunit, mitochondrial (human)" ; rdfs:comment "A succinate dehydrogenase [ubiquinone] cytochrome b small subunit, mitochondrial that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000014566 , obo:PR_000029067 . obo:PR_000028799 a rdfs:Class ; rdfs:label "tubulin" ; rdfs:comment "A protein with a core domain composition consisting of a Tubulin/FtsZ family, GTPase domain (Pfam:PF00091) at the N terminus, and a Tubulin C-terminal domain (Pfam:PF03953). Tubulins possess GTPase activity, and are the principle components of microtubules." ; rdfs:subClassOf obo:PR_000000001 . obo:OAE_0002527 a rdfs:Class ; rdfs:label "palpitations AE"@en ; rdfs:comment "An arrhythmia AE that has an outcome of palpitations, an abnormality of heartbeat characterized by simultaneous awareness of one’s pulse and discomfort." ; rdfs:subClassOf obo:OAE_0000660 . a rdfs:Class ; rdfs:label "Motion Sickness [Disease/Finding]" ; rdfs:subClassOf . obo:VO_0005229 a rdfs:Class ; rdfs:label "COVIran Barakat"@en ; rdfs:comment "A SARS-CoV-2 inactivated vaccine by Shifa Pharmed" ; rdfs:subClassOf obo:VO_0005201 , obo:VO_0005266 . obo:PR_O43823 a rdfs:Class ; rdfs:label "A-kinase anchor protein 8 (human)" ; rdfs:comment "An A-kinase anchor protein 8 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000003894 , obo:PR_000029067 . obo:PR_000000121 a rdfs:Class ; rdfs:label "Rho-associated protein kinase 2" ; rdfs:comment "A Rho-associated protein kinase that is a translation product of the human ROCK2 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000024 . obo:PR_Q99808 a rdfs:Class ; rdfs:label "equilibrative nucleoside transporter 1 (human)" ; rdfs:comment "An equilibrative nucleoside transporter 1 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000015054 , obo:PR_000029067 . obo:CIDO_0020075 a rdfs:Class ; rdfs:label "CirrusDx SARS-CoV-2 Assay" ; rdfs:seeAlso ; rdfs:subClassOf obo:CIDO_0000454 . obo:PR_000029108 a rdfs:Class ; rdfs:label "FAST kinase domain-containing protein 5, mitochondrial" ; rdfs:comment "A protein that is a translation product of the human FASTKD5 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:NCBITaxon_903595 a rdfs:Class ; rdfs:label "Kenya bat coronavirus BtKY57" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:CHEBI_23366 a rdfs:Class ; rdfs:label "compatible osmolytes" ; rdfs:subClassOf obo:CHEBI_25728 . obo:CHEBI_49318 a rdfs:Class ; rdfs:label "piperidine antibiotic" ; rdfs:subClassOf obo:CHEBI_25558 , obo:CHEBI_26151 . obo:VO_0004678 a rdfs:Class ; rdfs:label "RBD-rAAV-SARS-CoV" ; rdfs:subClassOf obo:VO_0012183 . obo:CIDO_0020257 a rdfs:Class ; rdfs:label "QuickVue SARS Antigen Test" ; rdfs:seeAlso ; rdfs:subClassOf obo:CIDO_0000454 . obo:CHEBI_29785 a rdfs:Class ; rdfs:label "nitro group" ; rdfs:subClassOf obo:CHEBI_33246 , obo:CHEBI_51144 . a rdfs:Class ; rdfs:label "Cardiovascular Abnormalities [Disease/Finding]" ; rdfs:subClassOf , . obo:NCBITaxon_591070 a rdfs:Class ; rdfs:label "Murine coronavirus RJHM/A" ; rdfs:subClassOf obo:NCBITaxon_11138 . obo:CHEBI_71466 a rdfs:Class ; rdfs:label "oleoyl ethanolamide" ; rdfs:comment "An N-(long-chain-acyl)ethanolamine that is the ethanolamide of oleic acid. The monounsaturated analogue of the endocannabinoid anandamide." ; rdfs:subClassOf obo:CHEBI_134158 , obo:CHEBI_15897 , obo:CHEBI_67197 . a rdfs:Class ; rdfs:label "Hematological Cell Destruction Alteration [PE]" ; rdfs:subClassOf . obo:CHEBI_75606 a rdfs:Class ; rdfs:label "hydroxamic acid ester" ; rdfs:comment "A carboxamide that is a hydroxamic acid in which the hydrogen of the hydroxy group is replaced by an organyl group." ; rdfs:subClassOf obo:CHEBI_37622 . obo:NCBITaxon_1679915 a rdfs:Class ; rdfs:label "Coronavirus RCoV/NSP65/Rha_pum/RSA/2008" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:PR_000002035 a rdfs:Class ; rdfs:label "beta-type platelet-derived growth factor receptor" ; rdfs:comment "A CSF-1/PDGF receptor-type tyrosine-protein kinase that is a translation product of the human PDGFRB gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000001810 . obo:CIDO_0000631 a rdfs:Class ; rdfs:label "S235F in SARS-CoV-2 N protein" ; rdfs:comment "An AA mutation or AA variant that has mutated an amino acid at position 235 into a phenylalanine in N protein." ; rdfs:subClassOf obo:CIDO_0000596 . obo:PR_Q9NSY1 a rdfs:Class ; rdfs:label "BMP-2-inducible protein kinase (human)" ; rdfs:comment "A BMP-2-inducible protein kinase that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000004773 , obo:PR_000029067 . a rdfs:Class ; rdfs:label "Yohimbine [Chemical/Ingredient]" ; rdfs:subClassOf . obo:OBI_0000453 a rdfs:Class ; rdfs:label "measure function"@en ; rdfs:comment "Measure function is a function that is borne by a processed material and realized in a process in which information about some entity is expressed relative to some reference."@en ; rdfs:subClassOf obo:BFO_0000034 . obo:NCBITaxon_305410 a rdfs:Class ; rdfs:label "SARS coronavirus B040" ; rdfs:subClassOf obo:NCBITaxon_694009 . obo:CIDO_0001135 a rdfs:Class ; rdfs:label "SARS-CoV2 orf8 protein binding to human SIL1"@en ; rdfs:comment "SARS-CoV2 orf8 protein binding to human SIL1, as evidented by an affinity-purification mass spectrometry experiment" ; rdfs:subClassOf obo:CIDO_0000051 . obo:CIDO_0000213 a rdfs:Class ; rdfs:label "SARS-CoV-2 structure protein synthesis"@en ; rdfs:subClassOf obo:CIDO_0000197 , obo:CIDO_0000212 . obo:PR_P25021 a rdfs:Class ; rdfs:label "histamine H2 receptor (human)" ; rdfs:comment "A histamine H2 receptor that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000001423 , obo:PR_000029067 . obo:CIDO_0000523 a rdfs:Class ; rdfs:label "LQEAIKVLNQSYINL" ; rdfs:comment "A coronavirus epitope that is part of some S protein from HCoV OC43 composed of the following amino acids LQEAIKVLNQSYINL" ; rdfs:subClassOf obo:CIDO_0000452 . obo:PR_P07306 a rdfs:Class ; rdfs:label "asialoglycoprotein receptor 1 (human)" ; rdfs:comment "An asialoglycoprotein receptor 1 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000004369 , obo:PR_000029067 . obo:CIDO_0000395 a rdfs:Class ; rdfs:label "SARS-CoV-2 B.1.7 virus"@en ; rdfs:comment """A SARS-CoV-2 Alpha variant with a majority of the following mutations: orf1ab:T1001I ,orf1ab:A1708D ,orf1ab:I2230T del:11288:9 ,del:21765:6, del:21991:3 ,S:N501Y ,S:A570D ,S:P681H ,S:T716I ,S:S982A ,S:D1118H ,Orf8:Q27* ,Orf8:R52I ,Orf8:Y73C ,N:D3L ,N:S235F""" ; rdfs:subClassOf obo:CIDO_0000371 , obo:CIDO_0000406 . obo:CIDO_0000702 a rdfs:Class ; rdfs:label "T716I in SARS-CoV-2 S protein" ; rdfs:comment "An AA mutation or AA variant that has mutated an amino acid at position 716 into a isoleucine in S protein." ; rdfs:subClassOf obo:CIDO_0001158 . obo:PR_000016049 a rdfs:Class ; rdfs:label "serine/threonine-protein kinase TAO2" ; rdfs:comment "A protein that is a translation product of the human TAOK2 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:CHEBI_38418 a rdfs:Class ; rdfs:label "1,3-thiazole" ; rdfs:subClassOf obo:CHEBI_48901 . obo:NCBITaxon_11123 a rdfs:Class ; rdfs:label "Avian infectious bronchitis virus (strain Beaudette M42)" ; rdfs:subClassOf obo:NCBITaxon_11120 . obo:DOID_5418 a rdfs:Class ; rdfs:label "schizoaffective disorder" ; rdfs:comment "A psychotic disorder that is characterized by recurring episodes of mood fluctuations and a loss of contact with reality." ; rdfs:subClassOf obo:DOID_2468 . obo:OBI_0001468 a rdfs:Class ; rdfs:label "cell specimen"@en ; rdfs:comment "A specimen primarily composed of a cell or cells collected from a multicellular organism or a cell culture." ; rdfs:subClassOf obo:OBI_0100051 . obo:DOID_5340 a rdfs:Class ; rdfs:label "anterograde amnesia" ; rdfs:comment "An amnestic disorder that involves the impaired or lost ability to memorize new things." ; rdfs:subClassOf obo:DOID_10914 . obo:PR_Q8N0Z8 a rdfs:Class ; rdfs:label "tRNA pseudouridine synthase-like 1 (human)" ; rdfs:comment "A tRNA pseudouridine synthase-like 1 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000013501 , obo:PR_000029067 . a rdfs:Class ; rdfs:label "Duodenal Diseases [Disease/Finding]" ; rdfs:subClassOf . obo:HP_0001662 a rdfs:Class ; rdfs:label "Bradycardia" ; rdfs:comment "A slower than normal heart rate (in adults, slower than 60 beats per minute)." ; rdfs:subClassOf obo:HP_0011675 . a rdfs:Class ; rdfs:label "Skin Diseases, Vascular [Disease/Finding]" ; rdfs:subClassOf . obo:CIDO_0000427 a rdfs:Class ; rdfs:label "coronavirus disease diagnosis conclusion"@en ; rdfs:comment "The representation of a conclusion of a diagnostic process for a coronavirus disease." ; rdfs:subClassOf obo:OGMS_0000073 . obo:CHEBI_31649 a rdfs:Class ; rdfs:label "teprenone" ; rdfs:comment "A terpene ketone in which a (9E,13E)-geranylgernayl group is bonded to one of the alpha-methyls of acetone (it is a mixture of 5E- and 5Z-geoisomers in a 3:2 ratio)." ; rdfs:subClassOf obo:CHEBI_26872 , obo:CHEBI_51867 . obo:OBI_0002541 a rdfs:Class ; rdfs:label "spleen specimen" ; rdfs:comment "A specimen that is derived from spleen." ; rdfs:subClassOf obo:OBI_0001479 . obo:PR_P05026 a rdfs:Class ; rdfs:label "sodium/potassium-transporting ATPase subunit beta-1 (human)" ; rdfs:comment "A sodium/potassium-transporting ATPase subunit beta-1 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000004439 , obo:PR_000029067 . obo:PR_000010429 a rdfs:Class ; rdfs:label "MAP kinase-interacting serine/threonine-protein kinase 1" ; rdfs:comment "A protein that is a translation product of the human MKNK1 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:CHEBI_63593 a rdfs:Class ; rdfs:label "1-glycosyltriazole" ; rdfs:comment "An N-glycosyl compound that consists of any triazole having a glycosyl residue attached at position 1." ; rdfs:subClassOf obo:CHEBI_21731 , obo:CHEBI_35727 . a rdfs:Class ; rdfs:label "Skin Diseases, Infectious [Disease/Finding]" ; rdfs:subClassOf , . obo:CIDO_0000926 a rdfs:Class ; rdfs:label "SARS-CoV2 nsp8 protein binding to human DDX10" ; rdfs:comment "SARS-CoV2 nsp8 protein binding to human DDX10, as evidented by an affinity-purification mass spectrometry experiment" ; rdfs:subClassOf obo:CIDO_0000582 . obo:CIDO_0000772 a rdfs:Class ; rdfs:label "SARS-CoV2 M protein binding to human TARS2" ; rdfs:comment "SARS-CoV2 M protein binding to human TARS2, as evidented by an affinity-purification mass spectrometry experiment" ; rdfs:subClassOf obo:CIDO_0000055 . obo:NCBITaxon_1679900 a rdfs:Class ; rdfs:label "Coronavirus RCoV/D_RMU10_590/Mic_arv/GER/2010" ; rdfs:subClassOf obo:NCBITaxon_2664420 . a rdfs:Class ; rdfs:label "Toremifene [Chemical/Ingredient]" ; rdfs:subClassOf . obo:CHEBI_71229 a rdfs:Class ; rdfs:label "telavancin" ; rdfs:comment "A glycopeptide that is vancomycin substituted at position N-3'' by a 2-(decylamino)ethyl group and at position C-29 by a (phosphonomethyl)aminomethyl group. Used as its hydrochloride salt for treatment of adults with complicated skin and skin structure infections caused by bacteria." ; rdfs:subClassOf obo:CHEBI_24396 . obo:NCBITaxon_1241932 a rdfs:Class ; rdfs:label "Hipposideros bat coronavirus HKU10" ; rdfs:subClassOf obo:NCBITaxon_1244203 . obo:PR_000008015 a rdfs:Class ; rdfs:label "alpha-galactosidase A" ; rdfs:comment "A protein that is a translation product of the human GLA gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:NCBITaxon_443239 a rdfs:Class ; rdfs:label "Human coronavirus HKU1 (isolate N1)" ; rdfs:subClassOf obo:NCBITaxon_290028 . obo:CIDO_0000369 a rdfs:Class ; rdfs:label "medical gloves"@en ; rdfs:comment "A respirator designed to protect the user from breathing in contaminants in the air, thus preserving the health of their respiratory tract." ; rdfs:subClassOf obo:CIDO_0000365 . obo:CHEBI_17062 a rdfs:Class ; rdfs:label "primary aliphatic amine" ; rdfs:subClassOf obo:CHEBI_32877 . obo:OBI_0600036 a rdfs:Class ; rdfs:label "establishing cell culture" ; rdfs:comment "a process through which a new type of cell culture or cell line is created, either through the isolation and culture of one or more cells from a fresh source, or the deliberate experimental modification of an existing cell culture (e.g passaging a primary culture to become a secondary culture or line, or the immortalization or stable genetic modification of an existing culture or line)." ; rdfs:subClassOf obo:OBI_0000094 . obo:CIDO_0000254 a rdfs:Class ; rdfs:label "endocytosis inhibitor role"@en ; rdfs:subClassOf obo:CHEBI_35222 . obo:CIDO_0000996 a rdfs:Class ; rdfs:label "SARS-CoV2 orf8 protein binding to human ERO1B" ; rdfs:comment "SARS-CoV2 orf8 protein binding to human ERO1B, as evidented by an affinity-purification mass spectrometry experiment" ; rdfs:subClassOf obo:CIDO_0000051 . a rdfs:Class ; rdfs:label "Hydroxyprogesterones [Chemical/Ingredient]" ; rdfs:subClassOf . obo:NCBITaxon_2509509 a rdfs:Class ; rdfs:label "Rhinacovirus" ; rdfs:subClassOf obo:NCBITaxon_693996 . obo:CHEBI_52625 a rdfs:Class ; rdfs:label "inorganic hydroxy compound" ; rdfs:subClassOf obo:CHEBI_24651 , obo:CHEBI_24835 . obo:GO_0044106 a rdfs:Class ; rdfs:label "cellular amine metabolic process" ; rdfs:comment "The chemical reactions and pathways involving any organic compound that is weakly basic in character and contains an amino or a substituted amino group, as carried out by individual cells. Amines are called primary, secondary, or tertiary according to whether one, two, or three carbon atoms are attached to the nitrogen atom." ; rdfs:subClassOf obo:GO_0034641 , obo:GO_1901564 . obo:NCBITaxon_33208 a rdfs:Class ; rdfs:label "Metazoa" ; rdfs:subClassOf obo:NCBITaxon_33154 . obo:PR_000004104 a rdfs:Class ; rdfs:label "AP-3 complex subunit beta-1" ; rdfs:comment "A protein that is a translation product of the human AP3B1 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:NCBITaxon_2042585 a rdfs:Class ; rdfs:label "Coronavirus PREDICT CoV-61" ; rdfs:subClassOf obo:NCBITaxon_366617 . obo:PR_P63218 a rdfs:Class ; rdfs:label "guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5 (human)" ; rdfs:comment "A guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000008110 , obo:PR_000029067 . obo:GO_0006584 a rdfs:Class ; rdfs:label "catecholamine metabolic process" ; rdfs:comment "The chemical reactions and pathways involving any of a group of physiologically important biogenic amines that possess a catechol (3,4-dihydroxyphenyl) nucleus and are derivatives of 3,4-dihydroxyphenylethylamine." ; rdfs:subClassOf obo:GO_0018958 , obo:GO_0044106 . obo:CIDO_0000373 a rdfs:Class ; rdfs:label "surgery mask"@en ; rdfs:comment "A surgical mask is a loose-fitting, disposable device that creates a physical barrier between the mouth and nose of the wearer and potential contaminants in the immediate environment." ; rdfs:subClassOf obo:CIDO_0000372 . obo:NCBITaxon_1699324 a rdfs:Class ; rdfs:label "Myotis Bat Alphacoronavirus strain YNXY_13C" ; rdfs:subClassOf obo:NCBITaxon_366617 . obo:CIDO_0000546 a rdfs:Class ; rdfs:label "SLWRVTAVHSDGMFV" ; rdfs:comment "A coronavirus epitope that is part of some S protein from HCoV NL63 composed of the following amino acids SLWRVTAVHSDGMFV" ; rdfs:subClassOf obo:CIDO_0000449 . obo:CHEBI_28159 a rdfs:Class ; rdfs:label "D-asparagine" ; rdfs:comment "An optically active form of asparagine having D-configuration." ; rdfs:subClassOf obo:CHEBI_16733 , obo:CHEBI_22653 . obo:NCBITaxon_389231 a rdfs:Class ; rdfs:label "Bat coronavirus (BtCoV/242/2005)" ; rdfs:subClassOf obo:NCBITaxon_389126 . obo:HP_0000820 a rdfs:Class ; rdfs:label "Abnormality of the thyroid gland" ; rdfs:comment "An abnormality of the thyroid gland." ; rdfs:subClassOf obo:HP_0000818 . obo:VO_0005402 a rdfs:Class ; rdfs:label "RQ3013"@en ; rdfs:comment "A SARS-CoV-2 RNA vaccine by Walvax Biotechnology and Shanghai RNACure Biopharma" ; rdfs:subClassOf obo:VO_0005198 . obo:NCBITaxon_1898672 a rdfs:Class ; rdfs:label "Rabbit coronavirus" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:NCBITaxon_1146858 a rdfs:Class ; rdfs:label "Bat coronavirus M.nattereri/UK/Sav/1108A" ; rdfs:subClassOf obo:NCBITaxon_366617 . obo:CIDO_0000294 a rdfs:Class ; rdfs:label "human male infected by SARS-CoV-2"@en ; rdfs:subClassOf obo:CIDO_0000292 . obo:OPMI_0000439 a rdf:Property ; rdfs:label "has increased susceptibility compared to female to"@en ; rdfs:comment "An object property that represents a relation between a person with a biological sex and a process where the person has an increased susceptbility to a process compared to corresponding female population" ; rdfs:range ; rdfs:subPropertyOf obo:OPMI_0000424 . obo:CHEBI_36615 a rdfs:Class ; rdfs:label "triterpenoid" ; rdfs:comment "Any terpenoid derived from a triterpene. The term includes compounds in which the C30 skeleton of the parent triterpene has been rearranged or modified by the removal of one or more skeletal atoms (generally methyl groups)." ; rdfs:subClassOf obo:CHEBI_26873 . obo:OAE_0000360 a rdfs:Class ; rdfs:label "paresthesia oral AE" ; rdfs:comment "a paresthesia AE that occurs in oral area." ; rdfs:subClassOf obo:OAE_0000392 . obo:OBI_0002783 a rdfs:Class ; rdfs:label "lower respiratory tract specimen" ; rdfs:comment "A specimen that is derived from the lower respiratory tract." ; rdfs:subClassOf obo:OBI_0002599 . obo:NCBITaxon_389238 a rdfs:Class ; rdfs:label "Bat coronavirus (BtCoV/359A/2005)" ; rdfs:subClassOf obo:NCBITaxon_389126 . obo:NCBITaxon_903612 a rdfs:Class ; rdfs:label "Kenya bat coronavirus BtKY74" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:CIDO_0020286 a rdfs:Class ; rdfs:label "SCoV-2 Detect IgM ELISA" ; rdfs:seeAlso ; rdfs:subClassOf obo:CIDO_0000454 . obo:PR_000015763 a rdfs:Class ; rdfs:label "stomatin" ; rdfs:comment "A protein that is a translation product of the human STOM gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:PR_000005935 a rdfs:Class ; rdfs:label "chondroitin sulfate glucuronyltransferase" ; rdfs:comment "A protein that is a translation product of the human CHPF2 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:VO_0005317 a rdfs:Class ; rdfs:label "Baiya SARS-CoV-2 Vax 1"@en ; rdfs:comment "A SARS-CoV-2 subunit vaccine by Baiya Phytopharm Co., Ltd." ; rdfs:subClassOf obo:VO_0005202 . obo:NCBITaxon_1532172 a rdfs:Class ; rdfs:label "Alphacoronavirus BtCoV/MSTM2/Min_nat/RSA/2010" ; rdfs:subClassOf obo:NCBITaxon_366617 . obo:PR_P35613 a rdfs:Class ; rdfs:label "basigin (human)" ; rdfs:comment "A basigin that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000001324 , obo:PR_000029067 . obo:CHEBI_77748 a rdfs:Class ; rdfs:label "EC 3.6.3.44 (xenobiotic-transporting ATPase) inhibitor" ; rdfs:comment "An EC 3.6.3.* (acid anhydride hydrolase catalysing transmembrane movement of substances) inhibitor that interferes with the action of xenobiotic-transporting ATPase (EC 3.6.3.44)." ; rdfs:subClassOf obo:CHEBI_76895 . obo:PR_Q86YV6 a rdfs:Class ; rdfs:label "myosin light chain kinase family member 4 (human)" ; rdfs:comment "A myosin light chain kinase family member 4 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000029067 , obo:PR_000029127 . obo:NCBITaxon_1679923 a rdfs:Class ; rdfs:label "Coronavirus RCoV/TP3_26/Rat_rat/THA/2005" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:OMRSE_00000096 a rdfs:Class ; rdfs:label "party to an insurance policy"@en ; rdfs:subClassOf obo:OMRSE_00000002 . obo:NCBITaxon_9895 a rdfs:Class ; rdfs:label "Bovidae" ; rdfs:subClassOf obo:NCBITaxon_35500 . obo:NCBITaxon_235414 a rdfs:Class ; rdfs:label "SARS coronavirus Sin2500" ; rdfs:subClassOf obo:NCBITaxon_694009 . obo:CHEBI_32557 a rdfs:Class ; rdfs:label "D-lysinium(1+)" ; rdfs:comment "An optically active form of lysinium having D-configuration." ; rdfs:subClassOf obo:CHEBI_32564 . obo:CIDO_0001211 a rdfs:Class ; rdfs:label "SARS-CoV-2 Nucleic Acid Detection Kit (CRISPR immunochromatography) (Hangzhou Zhongce Biotechnology Co., Ltd.)" ; rdfs:comment "Poduct storage conditions and expiration date: Box A should be stored at -20℃±5℃ in the dark, and box B should be stored at 10～30℃ in a dry place in the dark. The validity period is tentatively set for 6 months." ; rdfs:subClassOf obo:CIDO_0000021 . obo:CHEBI_29989 a rdfs:Class ; rdfs:label "D-glutamate(2-)" ; rdfs:subClassOf obo:CHEBI_29987 . obo:CIDO_0020086 a rdfs:Class ; rdfs:label "Color SARS CoV-2 Diagnostic Assay" ; rdfs:seeAlso ; rdfs:subClassOf obo:CIDO_0000454 . obo:OBI_2000009 a rdfs:Class ; rdfs:label "bodily fluid specimen" ; rdfs:comment "A specimen that is derived from some bodily fluid" ; rdfs:subClassOf obo:OBI_0001479 . obo:CIDO_0000642 a rdfs:Class ; rdfs:label "S1188L in SARS-CoV-2 pp1a protein" ; rdfs:comment "An AA mutation or AA variant that has mutated an amino acid at position 1188 into a leucine in pp1a." ; rdfs:subClassOf obo:CIDO_0001074 . obo:CHEBI_65296 a rdfs:Class ; rdfs:label "primary ammonium ion" ; rdfs:comment "An ammonium ion derivative resulting from the protonation of the nitrogen atom of a primary amino compound. Major species at pH 7.3." ; rdfs:subClassOf obo:CHEBI_25697 , obo:CHEBI_35274 . obo:CIDO_0001005 a rdfs:Class ; rdfs:label "Leronlimab" ; rdfs:subClassOf obo:CHEBI_23367 . obo:NCBITaxon_1415846 a rdfs:Class ; rdfs:label "Bat SARS-like coronavirus Rs4096" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:DRON_00014332 a rdfs:Class ; rdfs:label "bevacizumab" ; rdfs:subClassOf obo:OBI_0000047 . obo:OBI_1110046 a rdfs:Class ; rdfs:label "organ harvesting"@en ; rdfs:comment "The process of removing an organ from its source organism"@en ; rdfs:subClassOf obo:OBI_0600014 . a rdfs:Class ; rdfs:label "Myeloproliferative Disorders [Disease/Finding]" ; rdfs:subClassOf . obo:OPMI_0000479 a rdfs:Class ; rdfs:label "care site"@en ; rdfs:comment "A care site is a uniquely identified institutional (physical or organizational) unit where healthcare delivery is practiced, for example, office, ward, hospital, clinic, etc." ; rdfs:subClassOf obo:BFO_0000029 . obo:GO_0044260 a rdfs:Class ; rdfs:label "cellular macromolecule metabolic process" ; rdfs:comment "The chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass, as carried out by individual cells." ; rdfs:subClassOf obo:GO_0043170 , obo:GO_0044237 . obo:NCBITaxon_389144 a rdfs:Class ; rdfs:label "Bat coronavirus (BtCoV/A754/2005)" ; rdfs:subClassOf obo:NCBITaxon_389126 . obo:NCBITaxon_1541209 a rdfs:Class ; rdfs:label "Bat Hp-betacoronavirus/Zhejiang2013-4" ; rdfs:subClassOf obo:NCBITaxon_696098 . obo:PR_Q15375 a rdfs:Class ; rdfs:label "ephrin type-A receptor 7 (human)" ; rdfs:comment "An ephrin type-A receptor 7 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000007127 , obo:PR_000029067 . obo:PR_000015181 a rdfs:Class ; rdfs:label "sodium-dependent neutral amino acid transporter B(0)AT2" ; rdfs:comment "A protein that is a translation product of the human SLC6A15 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:PR_O75469-4 a rdfs:Class ; rdfs:subClassOf obo:PR_000000001 . a rdfs:Class ; rdfs:label "THIETHYLPERAZINE MALEATE" ; rdfs:subClassOf . obo:GO_0005254 a rdfs:Class ; rdfs:label "chloride channel activity" ; rdfs:comment "Enables the facilitated diffusion of a chloride (by an energy-independent process) involving passage through a transmembrane aqueous pore or channel without evidence for a carrier-mediated mechanism." ; rdfs:subClassOf obo:GO_0005253 , obo:GO_0015103 . obo:PR_000001579 a rdfs:Class ; rdfs:label "delta-type opioid receptor" ; rdfs:comment "An opioid receptor protein that is a translation product of the human OPRD1 gene or a 1:1 ortholog thereof. The preferred ligands are enkephalins." ; rdfs:subClassOf obo:PR_000001497 . obo:NCBITaxon_1225485 a rdfs:Class ; rdfs:label "Bat coronavirus Gabon/391/2009" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:NCBITaxon_1429863 a rdfs:Class ; rdfs:label "Betacoronavirus Pipistrellus/Italy/49967-19/2010" ; rdfs:subClassOf obo:NCBITaxon_696098 . obo:CHEBI_63299 a rdfs:Class ; rdfs:label "carbohydrate derivative" ; rdfs:comment "Any organooxygen compound derived from a carbohydrate by replacement of one or more hydroxy group(s) by an amino group, a thiol group or similar heteroatomic groups. The term also includes derivatives of these compounds." ; rdfs:subClassOf obo:CHEBI_36963 , obo:CHEBI_78616 . a rdfs:Class ; rdfs:label "Respiratory Distress Syndrome, Adult [Disease/Finding]" ; rdfs:subClassOf , . obo:CIDO_0020170 a rdfs:Class ; rdfs:label "iC SARS-CoV2 Test" ; rdfs:seeAlso ; rdfs:subClassOf obo:CIDO_0000454 . obo:CIDO_0020112 a rdfs:Class ; rdfs:label "DiaPlexQ Novel Coronavirus (2019-nCoV) Detection Kit" ; rdfs:seeAlso ; rdfs:subClassOf obo:CIDO_0000454 . obo:NCBITaxon_1477413 a rdfs:Class ; rdfs:label "Deltacoronavirus PDCoV/USA/Illinois136/2014" ; rdfs:subClassOf obo:NCBITaxon_1159905 . obo:OBI_0002537 a rdfs:Class ; rdfs:label "thyroid gland specimen" ; rdfs:comment "A specimen that is derived from thyroid gland." ; rdfs:subClassOf obo:OBI_0001479 . obo:CIDO_0020294 a rdfs:Class ; rdfs:label "Simplexa COVID-19 Direct" ; rdfs:seeAlso ; rdfs:subClassOf obo:CIDO_0000454 . a rdfs:Class ; rdfs:label "Multiple Myeloma [Disease/Finding]" ; rdfs:subClassOf , , , . obo:NCBITaxon_903602 a rdfs:Class ; rdfs:label "Kenya bat coronavirus BtKY64" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:CHEBI_35679 a rdfs:Class ; rdfs:label "antilipemic drug" ; rdfs:comment "A substance used to treat hyperlipidemia (an excess of lipids in the blood)." ; rdfs:subClassOf obo:CHEBI_23888 . obo:NCBITaxon_1788418 a rdfs:Class ; rdfs:label "Bat coronavirus HpBtCoV/3723" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:NCBITaxon_1699361 a rdfs:Class ; rdfs:label "Bat SARS-like coronavirus YNLF_34C" ; rdfs:subClassOf obo:NCBITaxon_694009 . a rdfs:Class ; rdfs:label "Staphylococcal Infections [Disease/Finding]" ; rdfs:subClassOf . obo:CHEBI_22712 a rdfs:Class ; rdfs:label "benzenes" ; rdfs:comment "Any benzenoid aromatic compound consisting of the benzene skeleton and its substituted derivatives." ; rdfs:subClassOf obo:CHEBI_33836 . obo:CHEBI_3380 a rdfs:Class ; rdfs:label "captopril" ; rdfs:comment "A L-proline derivative in which L-proline is substituted on nitrogen with a (2S)-2-methyl-3-sulfanylpropanoyl group. It is used as an anti-hypertensive ACE inhibitor drug." ; rdfs:subClassOf obo:CHEBI_46701 , obo:CHEBI_46766 , obo:CHEBI_47908 , obo:CHEBI_84186 . obo:CIDO_0020026 a rdfs:Class ; rdfs:label "Aptima SARS-CoV-2 assay" ; rdfs:seeAlso ; rdfs:subClassOf obo:CIDO_0000454 . obo:CHEBI_136849 a rdfs:Class ; rdfs:label "3-oxo-Delta(4)-steroid group" ; rdfs:comment "An organic group derived from any 3-oxo-Delta(4)-steroid." ; rdfs:subClassOf obo:CHEBI_33247 . obo:OAE_0000081 a rdfs:Class ; rdfs:label "discomfort AE" ; rdfs:comment "a sensory capability AE that resuls in an uncomfortable feeling. " ; rdfs:subClassOf obo:OAE_0000582 . obo:CIDO_0001225 a rdfs:Class ; rdfs:label "Respiratory Virus Nucleic Acid Detection Kit (Isothermal Amplification Chip Method) (Chengdu Capitalbio Jinxin Bio-Technology Co., Ltd.)" ; rdfs:comment "Manufacturor: Chengdu Capitalbio Jinxin Bio-Technology Co., Ltd. 成都博奥晶芯生物科技有限公司" ; rdfs:subClassOf obo:CIDO_0000021 . obo:NCBITaxon_1766554 a rdfs:Class ; rdfs:label "Swine enteric coronavirus" ; rdfs:subClassOf obo:NCBITaxon_693997 . obo:CHEBI_60601 a rdfs:Class ; rdfs:label "delta-opioid agent" ; rdfs:comment "Any agent that acts on a delta-opioid receptor." ; rdfs:subClassOf obo:CHEBI_60598 . obo:OBI_0000908 a rdfs:Class ; rdfs:label "labeled DNA extract" ; rdfs:comment "a labeled specimen that is the output of a labeling process and has grain labeled DNA to be able to detect DNA in future experiments." ; rdfs:subClassOf obo:OBI_0001143 . obo:CHEBI_32856 a rdfs:Class ; rdfs:label "D-valinium" ; rdfs:comment "The D-enantiomer of valinium." ; rdfs:subClassOf obo:CHEBI_32860 . obo:NCBITaxon_241628 a rdfs:Class ; rdfs:label "SARS coronavirus TWC2" ; rdfs:subClassOf obo:NCBITaxon_694009 . obo:CHEBI_26155 a rdfs:Class ; rdfs:label "plant growth regulator" ; rdfs:comment "A chemical, natural or artificial, that can affect the rate of growth of a plant." ; rdfs:subClassOf obo:CHEBI_39317 . obo:CHEBI_59779 a rdfs:Class ; rdfs:label "cyclic ketal" ; rdfs:comment "A ketal in the molecule of which the ketal carbon and one or both oxygen atoms thereon are members of a ring." ; rdfs:subClassOf obo:CHEBI_38104 , obo:CHEBI_59777 . obo:CIDO_0000682 a rdfs:Class ; rdfs:label "N856K in SARS-CoV-2 S protein" ; rdfs:comment "An AA mutation or AA variant that has mutated an amino acid at position 856 into a lysine in S protein." ; rdfs:subClassOf obo:CIDO_0000595 . obo:CHEBI_66901 a rdfs:Class ; rdfs:label "ivacaftor" ; rdfs:comment "An aromatic amide obtained by formal condensation of the carboxy group of 4-oxo-1,4-dihydroquinoline-3-carboxylic acid with the amino group of 5-amino-2,4-di-tert-butylphenol. Used for the treatment of cystic fibrosis." ; rdfs:subClassOf obo:CHEBI_23765 , obo:CHEBI_29347 , obo:CHEBI_33853 , obo:CHEBI_62733 . obo:CHEBI_50184 a rdfs:Class ; rdfs:label "ion transport inhibitor" ; rdfs:comment "A compound which inhibits the movement of an ion across an energy-transducing cell membrane." ; rdfs:subClassOf obo:CHEBI_38632 . obo:GO_0043408 a rdfs:Class ; rdfs:label "regulation of MAPK cascade" ; rdfs:comment "Any process that modulates the frequency, rate or extent of signal transduction mediated by the MAP kinase (MAPK) cascade." ; rdfs:subClassOf obo:GO_1902531 . a rdfs:Class ; rdfs:label "B [Preparations]" ; rdfs:subClassOf . obo:CHEBI_2500 a rdfs:Class ; rdfs:label "Aescin" ; rdfs:subClassOf obo:CHEBI_61778 . obo:CHEBI_16716 a rdfs:Class ; rdfs:label "benzene" ; rdfs:comment "A six-carbon aromatic annulene in which each carbon atom donates one of its two 2p electrons into a delocalised pi system. A toxic, flammable liquid byproduct of coal distillation, it is used as an industrial solvent. Benzene is a carcinogen that also damages bone marrow and the central nervous system." ; rdfs:subClassOf obo:CHEBI_134179 , obo:CHEBI_22712 , obo:CHEBI_33842 . obo:CIDO_0001034 a rdfs:Class ; rdfs:label "Inbakicept" ; rdfs:subClassOf obo:CHEBI_23367 . obo:BFO_0000038 a rdfs:Class ; rdfs:label "one-dimensional temporal region"@en ; rdfs:subClassOf obo:BFO_0000008 . obo:HP_0001649 a rdfs:Class ; rdfs:label "Tachycardia" ; rdfs:comment "A rapid heartrate that exceeds the range of the normal resting heartrate for age." ; rdfs:subClassOf obo:HP_0011675 . obo:CIDO_0001200 a rdfs:Class ; rdfs:label "Multiple Real-Time PCR Kit for Detection of 2019-nCoV. (Daan Gene Co.,ltd.)" ; rdfs:comment "Poduct storage conditions and expiration date: The kit is stored at -20±5℃, and the validity period is tentatively set for 6 months." ; rdfs:subClassOf obo:CIDO_0000021 . obo:PR_O60573 a rdfs:Class ; rdfs:label "eukaryotic translation initiation factor 4E type 2 (human)" ; rdfs:comment "A eukaryotic translation initiation factor 4E type 2 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000006992 , obo:PR_000029067 . obo:CHEBI_76939 a rdfs:Class ; rdfs:label "EC 3.6.4.10 (non-chaperonin molecular chaperone ATPase) inhibitor" ; rdfs:comment "An EC 3.6.4.* (hydrolases acting on ATP; involved in cellular and subcellular movement) inhibitor that interferes with the action of a non-chaperonin molecular chaperone ATPase (EC 3.6.4.10)." ; rdfs:subClassOf obo:CHEBI_76938 . obo:CHEBI_85185 a rdfs:Class ; rdfs:label "hepatitis C virus nonstructural protein 5A inhibitor" ; rdfs:comment "Any inhibitor of hepatitis C virus nonstructural protein 5A." ; rdfs:subClassOf obo:CHEBI_35222 , obo:CHEBI_52206 . obo:CHEBI_147283 a rdfs:Class ; rdfs:label "cinanserin(1+)" ; rdfs:comment "An ammonium ion derivative that is the conjugate acid of cinanserin, obtained by the protonation of the tertiary amino group. It is the major microspecies at pH 7.3." ; rdfs:subClassOf obo:CHEBI_35274 . obo:CHEBI_29347 a rdfs:Class ; rdfs:label "monocarboxylic acid amide" ; rdfs:comment "A carboxamide derived from a monocarboxylic acid." ; rdfs:subClassOf obo:CHEBI_37622 . obo:PR_000001450 a rdfs:Class ; rdfs:label "fibroblast growth factor receptor 3" ; rdfs:comment "A fibroblast growth factor receptor that is a translation product of the human FGFR3 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000001349 . a rdfs:Class ; rdfs:label "Midazolam [Chemical/Ingredient]" ; rdfs:subClassOf . obo:CIDO_0001151 a rdfs:Class ; rdfs:label "SARS-CoV-2 E protein amino acid deletion"@en ; rdfs:comment "A SARS-CoV-2 protein AA deletion that affected a SARS-CoV-2 E protein." ; rdfs:subClassOf obo:CIDO_0000614 . obo:GO_0038083 a rdfs:Class ; rdfs:label "peptidyl-tyrosine autophosphorylation" ; rdfs:comment "The phosphorylation by a protein of one or more of its own tyrosine amino acid residues, or a tyrosine residue on an identical protein." ; rdfs:subClassOf obo:GO_0018108 , obo:GO_0046777 . obo:NCBITaxon_722424 a rdfs:Class ; rdfs:label "SARS coronavirus Rs_672/2006" ; rdfs:subClassOf obo:NCBITaxon_694009 . obo:VO_0005407 a rdfs:Class ; rdfs:label "COVID-19 mRNA vaccine by CanSino Biologics"@en ; rdfs:comment "A SARS-CoV-2 RNA vaccine by CanSino Biologics Inc." ; rdfs:subClassOf obo:VO_0005198 . obo:NCBITaxon_9903 a rdfs:Class ; rdfs:label "Bos" ; rdfs:subClassOf obo:NCBITaxon_27592 . obo:CIDO_0000517 a rdfs:Class ; rdfs:label "GSSSRSFFEDLLFDK" ; rdfs:comment "A coronavirus epitope that is part of some S protein from HCoV HKU1 composed of the following amino acids GSSSRSFFEDLLFDK" ; rdfs:subClassOf obo:CIDO_0000409 . a rdfs:Class ; rdfs:label "Malaria, Avian [Disease/Finding]" ; rdfs:subClassOf . obo:VO_0005158 a rdfs:Class ; rdfs:label "Oxford–AstraZeneca COVID-19 vaccine" ; rdfs:comment "A SARS-CoV2 recombinat vector vaccine made of a chimpanzee adenovirus-vectored vaccine expressing the SARS-CoV-2 spike protein" ; rdfs:subClassOf obo:VO_0005268 . obo:VO_0000462 a rdf:Property ; rdfs:label "induced by vaccination of"@en ; rdfs:comment "an object property that specifies a process that is induced by vaccination of a vaccine" ; rdfs:range obo:VO_0000001 . obo:CHEBI_33636 a rdfs:Class ; rdfs:label "bicyclic compound" ; rdfs:comment "A molecule that features two fused rings." ; rdfs:subClassOf obo:CHEBI_33595 . obo:CIDO_0000966 a rdfs:Class ; rdfs:label "SARS-CoV2 orf10 protein binding to human MAP7D1" ; rdfs:comment "SARS-CoV2 orf10 protein binding to human MAP7D1, as evidented by an affinity-purification mass spectrometry experiment" ; rdfs:subClassOf obo:CIDO_0000050 . obo:DOID_6680 a rdfs:Class ; rdfs:label "Capgras syndrome" ; rdfs:comment "A delusional disorder in which a person holds a delusion that a friend, spouse, parent, or other close family member has been replaced by an identical-looking impostor." ; rdfs:subClassOf obo:DOID_778 . obo:CHEBI_135288 a rdfs:Class ; rdfs:label "chlorphenoxamine" ; rdfs:subClassOf obo:CHEBI_51614 . obo:CHEBI_31781 a rdfs:Class ; rdfs:label "lopinavir" ; rdfs:comment "A dicarboxylic acid diamide that is amphetamine is substituted on nitrogen by a (2,6-dimethylphenoxy)acetyl group and on the carbon alpha- to nitrogen by a (1S,3S)-1-hydroxy-3-{[(2S)-3-methyl-2-(2-oxotetrahydropyrimidin-1-yl)butanoyl]amino}-4-phenylbutyl group. An antiretroviral of the protease inhibitor class, it is used against HIV infections as a fixed-dose combination with another protease inhibitor, ritonavir." ; rdfs:subClassOf obo:CHEBI_35338 , obo:CHEBI_35779 . obo:NCBITaxon_2126098 a rdfs:Class ; rdfs:label "Bat coronavirus GCCDC1" ; rdfs:subClassOf obo:NCBITaxon_696098 . obo:CHEBI_32864 a rdfs:Class ; rdfs:label "L-prolinium" ; rdfs:comment "An optically active form of prolinium having L-configuration." ; rdfs:subClassOf obo:CHEBI_32872 . obo:CHEBI_50858 a rdfs:Class ; rdfs:label "corticosteroid" ; rdfs:comment "A natural or synthetic analogue of the hormones secreted by the adrenal gland." ; rdfs:subClassOf obo:CHEBI_35341 . a rdfs:Class ; rdfs:label "Ectoparasitic Infestations [Disease/Finding]" ; rdfs:subClassOf . obo:CIDO_0000018 a rdfs:Class ; rdfs:label "COVID-19 diagnostic process by serological assay"@en ; rdfs:comment "A COVID-19 diagnostic process that uses a serological assay that tests the serum from the blood specimen" ; rdfs:subClassOf obo:CIDO_0000424 . obo:HP_0003326 a rdfs:Class ; rdfs:label "Myalgia" ; rdfs:comment "Pain in muscle." ; rdfs:subClassOf obo:HP_0012531 . obo:CHEBI_33408 a rdfs:Class ; rdfs:label "pnictogen oxoacid" ; rdfs:subClassOf obo:CHEBI_24833 , obo:CHEBI_33302 . obo:CHEBI_50745 a rdfs:Class ; rdfs:label "progestogen" ; rdfs:comment "A compound that interacts with progesterone receptors in target tissues to bring about effects similar to those of progesterone." ; rdfs:subClassOf obo:CHEBI_50112 . obo:CIDO_0000116 a rdfs:Class ; rdfs:label "coronavirus assembly inside cell"@en ; rdfs:comment "A coronavirus process that involves in the virus assembly inside the host cell" ; rdfs:subClassOf obo:CIDO_0000198 . obo:NCBITaxon_2509480 a rdfs:Class ; rdfs:label "Duvinacovirus" ; rdfs:subClassOf obo:NCBITaxon_693996 . obo:NCBITaxon_304858 a rdfs:Class ; rdfs:label "SARS coronavirus A022" ; rdfs:subClassOf obo:NCBITaxon_694009 . obo:NCBITaxon_1696541 a rdfs:Class ; rdfs:label "Alphacoronavirus Pip1_Cr_FR_2014" ; rdfs:subClassOf obo:NCBITaxon_366617 . obo:NCBITaxon_2664184 a rdfs:Class ; rdfs:label "Erinaceus hedgehog coronavirus HKU31" ; rdfs:subClassOf obo:NCBITaxon_2664183 . obo:PR_000006655 a rdfs:Class ; rdfs:label "diphthine methyl ester synthase" ; rdfs:comment "A protein that is a translation product of the human DPH5 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . a rdfs:Class ; rdfs:label "Protozoan Infections [Disease/Finding]" ; rdfs:subClassOf . obo:GO_0010562 a rdfs:Class ; rdfs:label "positive regulation of phosphorus metabolic process" ; rdfs:comment "Any process that increases the frequency, rate or extent of the chemical reactions and pathways involving phosphorus or compounds containing phosphorus." ; rdfs:subClassOf obo:GO_0031325 , obo:GO_0051174 . obo:GO_0001994 a rdfs:Class ; rdfs:label "norepinephrine-epinephrine vasoconstriction involved in regulation of systemic arterial blood pressure" ; rdfs:comment "A process that results in a decrease in the diameter of an artery during the norepinephrine-epinephrine response to decreased blood pressure." ; rdfs:subClassOf obo:GO_0042310 . obo:GO_0009056 a rdfs:Class ; rdfs:label "catabolic process" ; rdfs:comment "The chemical reactions and pathways resulting in the breakdown of substances, including the breakdown of carbon compounds with the liberation of energy for use by the cell or organism." ; rdfs:subClassOf obo:GO_0008152 . a rdfs:Class ; rdfs:label "Skin Ulcer [Disease/Finding]" ; rdfs:subClassOf . a rdfs:Class ; rdfs:label "Immunologic Activity Alteration [PE]" ; rdfs:subClassOf . obo:PR_000004205 a rdfs:Class ; rdfs:label "ADP-ribosylation factor 6" ; rdfs:comment "A protein that is a translation product of the human ARF6 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:CHEBI_53746 a rdfs:Class ; rdfs:label "EC 1.1.1.205 (IMP dehydrogenase) inhibitor" ; rdfs:comment "An EC 1.1.1.* (oxidoreductase acting on donor CH-OH group, NAD(+) or NADP(+) acceptor) inhibitor that interferes with the action of IMP dehydrogenase (EC 1.1.1.205), so blocking de novo biosynthesis of purine nucleotides." ; rdfs:subClassOf obo:CHEBI_76835 . obo:OBI_0000684 a rdfs:Class ; rdfs:label "specimen collection objective" ; rdfs:comment "A objective specification to obtain a material entity for potential use as an input during an investigation." ; rdfs:subClassOf obo:IAO_0000005 . obo:GO_0008217 a rdfs:Class ; rdfs:label "regulation of blood pressure" ; rdfs:comment "Any process that modulates the force with which blood travels through the circulatory system. The process is controlled by a balance of processes that increase pressure and decrease pressure." ; rdfs:subClassOf obo:GO_0065008 . obo:DRON_00014441 a rdfs:Class ; rdfs:label "Trichlormethiazide" ; rdfs:subClassOf obo:OBI_0000047 . obo:PR_P49454 a rdfs:Class ; rdfs:label "centromere protein F (human)" ; rdfs:comment "A centromere protein F that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000005327 , obo:PR_000029067 . obo:CIDO_0000732 a rdfs:Class ; rdfs:label "SARS-CoV2 E protein binding to human CWC27" ; rdfs:comment "SARS-CoV2 E protein binding to human CWC27, as evidented by an affinity-purification mass spectrometry experiment" ; rdfs:subClassOf obo:CIDO_0000046 . obo:NCBITaxon_31624 a rdfs:Class ; rdfs:label "Avian infectious bronchitis virus (strain GRAY)" ; rdfs:subClassOf obo:NCBITaxon_11120 . obo:IDO_0000555 a rdfs:Class ; rdfs:label "disinfectant"@en ; rdfs:comment "A material entity bearing a disinfectant role."@en ; rdfs:subClassOf obo:BFO_0000040 . obo:NCBITaxon_296839 a rdfs:Class ; rdfs:label "SARS coronavirus PC4-145" ; rdfs:subClassOf obo:NCBITaxon_694009 . obo:PR_000012722 a rdfs:Class ; rdfs:label "phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform" ; rdfs:comment "A protein that is a translation product of the human PIK3CG gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:CIDO_0020152 a rdfs:Class ; rdfs:label "Genetron SARS-CoV-2 RNA Test" ; rdfs:seeAlso ; rdfs:subClassOf obo:CIDO_0000454 . a rdfs:Class ; rdfs:label "Sensation Disorders [Disease/Finding]" ; rdfs:subClassOf . obo:CIDO_0000042 a rdfs:Class ; rdfs:label "COVID-19 test sensitivity"@en ; rdfs:comment "A test sensitivity for the COVID-19 disease" ; rdfs:subClassOf obo:OBCS_0000094 . a rdfs:Class ; rdfs:label "Genital Diseases, Male [Disease/Finding]" ; rdfs:subClassOf . obo:NCBITaxon_756588 a rdfs:Class ; rdfs:label "Infectious bronchitis virus 4/91" ; rdfs:subClassOf obo:NCBITaxon_11120 . obo:CHEBI_3424 a rdfs:Class ; rdfs:label "carnitinium" ; rdfs:comment "A quaternary ammonium ion that is the the conjugate acid of carnitine." ; rdfs:subClassOf obo:CHEBI_35267 . a rdfs:Class ; rdfs:label "Lupus Erythematosus, Discoid [Disease/Finding]" ; rdfs:subClassOf . obo:PR_Q2M2I8 a rdfs:Class ; rdfs:label "AP2-associated protein kinase 1 (human)" ; rdfs:comment "An AAK1 gene translation product (human), isoforms h1 and h2." ; rdfs:subClassOf obo:PR_000050380 . obo:GO_0044265 a rdfs:Class ; rdfs:label "cellular macromolecule catabolic process" ; rdfs:comment "The chemical reactions and pathways resulting in the breakdown of a macromolecule, any large molecule including proteins, nucleic acids and carbohydrates, as carried out by individual cells." ; rdfs:subClassOf obo:GO_0009057 , obo:GO_0044248 , obo:GO_0044260 . obo:CHEBI_4551 a rdfs:Class ; rdfs:label "digoxin" ; rdfs:comment "A cardenolide glycoside that is digitoxin beta-hydroxylated at C-12. A cardiac glycoside extracted from the foxglove plant, Digitalis lanata, it is used to control ventricular rate in atrial fibrillation and in the management of congestive heart failure with atrial fibrillation, but the margin between toxic and therapeutic doses is small." ; rdfs:subClassOf obo:CHEBI_38092 , obo:CHEBI_61655 . obo:GO_0009719 a rdfs:Class ; rdfs:label "response to endogenous stimulus" ; rdfs:comment "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus arising within the organism." ; rdfs:subClassOf obo:GO_0050896 . obo:NCBITaxon_749431 a rdfs:Class ; rdfs:label "Pintail coronavirus PBA-16" ; rdfs:subClassOf obo:NCBITaxon_749416 . obo:CIDO_0000851 a rdfs:Class ; rdfs:label "SARS-CoV2 nsp13 protein binding to human PCNT" ; rdfs:comment "SARS-CoV2 nsp13 protein binding to human PCNT, as evidented by an affinity-purification mass spectrometry experiment" ; rdfs:subClassOf obo:CIDO_0000058 . obo:PR_000010329 a rdfs:Class ; rdfs:label "tyrosine-protein kinase Mer" ; rdfs:comment "A protein that is a translation product of the human MERTK gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:CIDO_0020033 a rdfs:Class ; rdfs:label "Assurance SARS-CoV-2 Panel DTC" ; rdfs:seeAlso ; rdfs:subClassOf obo:CIDO_0000454 . obo:CHEBI_48876 a rdfs:Class ; rdfs:label "muscarinic antagonist" ; rdfs:comment "A drug that binds to but does not activate muscarinic cholinergic receptors, thereby blocking the actions of endogenous acetylcholine or exogenous agonists." ; rdfs:subClassOf obo:CHEBI_48873 . obo:NCBITaxon_1385427 a rdfs:Class ; rdfs:label "Betacoronavirus Erinaceus/VMC/DEU/2012" ; rdfs:subClassOf obo:NCBITaxon_1965093 . obo:CIDO_0000482 a rdfs:Class ; rdfs:label "QPFSFSFRDELGVRV" ; rdfs:comment "A coronavirus epitope that is part of some S protein from HCoV NL63 composed of the following amino acids QPFSFSFRDELGVRV" ; rdfs:subClassOf obo:CIDO_0000449 . obo:CIDO_0000156 a rdfs:Class ; rdfs:label "SARS-CoV-2 transmission"@en ; rdfs:subClassOf obo:CIDO_0000155 . obo:NCBITaxon_931898 a rdfs:Class ; rdfs:label "Alphacoronavirus Eptesicus fuscus/Appalachian Ridge/P1-C676/IT/USA/2009" ; rdfs:subClassOf obo:NCBITaxon_366617 . obo:PR_000014489 a rdfs:Class ; rdfs:label "sterol regulatory element-binding protein cleavage-activating protein" ; rdfs:comment "A protein that is a translation product of the human SCAP gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:CHEBI_51721 a rdfs:Class ; rdfs:label "alpha,beta-unsaturated ketone" ; rdfs:comment "A ketone of general formula R(1)R(2)C=CR(3)-C(=O)R(4) (R(4) =/= H) or R(1)C#C-C(=O)R(2) (R(2) =/= H) in which the ketonic C=O function is conjugated to an unsaturated C-C bond at the alpha,beta position." ; rdfs:subClassOf obo:CHEBI_17087 . obo:CIDO_0000438 a rdfs:Class ; rdfs:label "presumptive positive COVID-19 diagnosis conclusion"@en ; rdfs:comment "The representation of a presumptive positive conclusion of a diagnostic process for the COVID-19 coronavirus disease." ; rdfs:subClassOf obo:CIDO_0000430 . obo:CIDO_0020145 a rdfs:Class ; rdfs:label "FTD SARS-CoV-2" ; rdfs:seeAlso ; rdfs:subClassOf obo:CIDO_0000454 . a rdfs:Class ; rdfs:label "Ergotamine [Chemical/Ingredient]" ; rdfs:subClassOf . obo:CIDO_0000870 a rdfs:Class ; rdfs:label "SARS-CoV2 nsp2 protein binding to human FKBP15" ; rdfs:comment "SARS-CoV2 nsp2 protein binding to human FKBP15, as evidented by an affinity-purification mass spectrometry experiment" ; rdfs:subClassOf obo:CIDO_0000580 . obo:OAE_0000557 a rdfs:Class ; rdfs:label "inflammation AE" ; rdfs:comment "an immune system disorder AE that results in complex biological response of vascular tissues to harmful stimuli, such as pathogens, damaged cells, or irritants. Inflammation is a protective attempt by the organism to remove the injurious stimuli as well as initiate the healing process for the tissue greater than expected response to injury, infection, or insult."@en ; rdfs:subClassOf obo:OAE_0000476 . obo:GO_0071867 a rdfs:Class ; rdfs:label "response to monoamine" ; rdfs:comment "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a monoamine stimulus. A monoamine is any of a group of molecular messengers that contain one amino group that is connected to an aromatic ring by ethylene group (-CH2-CH2-). Monoamines are derived from the aromatic amino acids phenylalanine, tyrosine, histidine and tryptophan." ; rdfs:subClassOf obo:GO_0010243 . obo:IDO_0000598 a rdfs:Class ; rdfs:label "host living with infected household contact"@en ; rdfs:comment "A host exposure to environment with infectious agent where the environment is a household that also has an infected host"@en ; rdfs:subClassOf obo:IDO_0000597 . obo:NCBITaxon_454963 a rdfs:Class ; rdfs:label "Bovine coronavirus E-AH187-TC" ; rdfs:subClassOf obo:NCBITaxon_422220 . obo:PR_P62873 a rdfs:Class ; rdfs:label "guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 (human)" ; rdfs:comment "A guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000008095 , obo:PR_000029067 . obo:GO_0010629 a rdfs:Class ; rdfs:label "negative regulation of gene expression" ; rdfs:comment "Any process that decreases the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product (protein or RNA)." ; rdfs:subClassOf obo:GO_0010468 , obo:GO_0010605 . obo:VO_0005142 a rdfs:Class ; rdfs:label "ZF2001" ; rdfs:comment "A SARS-CoV-2 subunit vaccine composed of the SARS-CoV-2 S protein receptor-binding domain produced in Chinese hamster ovary (CHO) cells and adjuvant aluminum hydroxide." ; rdfs:subClassOf obo:VO_0005269 . obo:HP_0011690 a rdfs:Class ; rdfs:label "Permanent junctional reciprocating tachycardia" ; rdfs:comment "An incessant orthodromic tachycardia with anterograde conduction over the atrioventricular node and by retrograde conduction via an accessory pathway usually located in the posteroseptal region with slow and decremental conduction." ; rdfs:subClassOf obo:HP_0011689 . obo:NCBITaxon_228406 a rdfs:Class ; rdfs:label "SARS coronavirus BJ02" ; rdfs:subClassOf obo:NCBITaxon_694009 . obo:CIDO_0001214 a rdfs:Class ; rdfs:label "Multiple Real-Time PCR Kit for Detection of 2019-nCoV. (Daan Gene Co.,ltd.)" ; rdfs:comment "Poduct storage conditions and expiration date: The kit is stored at -20±5℃ and has a validity period of 9 months." ; rdfs:subClassOf obo:CIDO_0000021 . obo:GO_0045860 a rdfs:Class ; rdfs:label "positive regulation of protein kinase activity" ; rdfs:comment "Any process that activates or increases the frequency, rate or extent of protein kinase activity." ; rdfs:subClassOf obo:GO_0001934 , obo:GO_0033674 , obo:GO_0045859 . obo:CIDO_0000326 a rdfs:Class ; rdfs:label "SVASQSIIAYTMSLG"@en ; rdfs:subClassOf obo:CIDO_0000314 . obo:PR_000060149 a rdfs:Class ; rdfs:label "WASH complex subunit 4" ; rdfs:comment "A protein that is a translation product of the human WASHC4 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:NCBITaxon_9675 a rdfs:Class ; rdfs:label "Paguma larvata" ; rdfs:subClassOf obo:NCBITaxon_9674 . obo:NCBITaxon_422134 a rdfs:Class ; rdfs:label "White-tailed deer coronavirus US/OH-WD470/1994" ; rdfs:subClassOf obo:NCBITaxon_11128 . obo:CIDO_0000485 a rdfs:Class ; rdfs:label "FKFDEPSDATDFIRV" ; rdfs:comment "A coronavirus epitope that is part of some S protein from HCoV HKU1 composed of the following amino acids FKFDEPSDATDFIRV" ; rdfs:subClassOf obo:CIDO_0000450 . obo:CIDO_0000923 a rdfs:Class ; rdfs:label "SARS-CoV2 nsp8 protein binding to human AATF" ; rdfs:comment "SARS-CoV2 nsp8 protein binding to human AATF, as evidented by an affinity-purification mass spectrometry experiment" ; rdfs:subClassOf obo:CIDO_0000582 . a rdfs:Class ; rdfs:label "Dysentery [Disease/Finding]" ; rdfs:subClassOf , . obo:CHEBI_34999 a rdfs:Class ; rdfs:label "teicoplanin A3-1" ; rdfs:comment "A glycopeptide consisting of a macropolycyclic heptapeptide in which a phenolic hydroxy group has been converted to its alpha-D-mannoside while a secondary alcohol group has been converted to the corresponding 2-acetamido-2-deoxy-beta-D-glucoside." ; rdfs:subClassOf obo:CHEBI_22160 , obo:CHEBI_24396 , obo:CHEBI_26191 , obo:CHEBI_26195 , obo:CHEBI_35618 , obo:CHEBI_51026 , obo:CHEBI_83403 . obo:GO_0006464 a rdfs:Class ; rdfs:label "cellular protein modification process" ; rdfs:comment "The covalent alteration of one or more amino acids occurring in proteins, peptides and nascent polypeptides (co-translational, post-translational modifications) occurring at the level of an individual cell. Includes the modification of charged tRNAs that are destined to occur in a protein (pre-translation modification)." ; rdfs:subClassOf obo:GO_0036211 , obo:GO_0044267 . obo:OPMI_0000544 a rdfs:Class ; rdfs:label "primary referral diagnosis status"@en ; rdfs:subClassOf obo:OPMI_0000526 . obo:CHEBI_17359 a rdfs:Class ; rdfs:label "sulfite" ; rdfs:comment "A sulfur oxoanion that is the conjugate base of hydrogen sulfite (H2SO3)." ; rdfs:subClassOf obo:CHEBI_33482 , obo:CHEBI_48154 , obo:CHEBI_79388 . obo:HP_0003119 a rdfs:Class ; rdfs:label "Abnormal circulating lipid concentration" ; rdfs:comment "Any deviation from the normal concentration of a lipid in the blood circulation." ; rdfs:subClassOf obo:HP_0032180 . obo:NCBITaxon_389239 a rdfs:Class ; rdfs:label "Bat coronavirus (BtCoV/363A/2005)" ; rdfs:subClassOf obo:NCBITaxon_389126 . obo:NCBITaxon_384349 a rdfs:Class ; rdfs:label "Human coronavirus NO/0643/05" ; rdfs:subClassOf obo:NCBITaxon_384335 . obo:NCBITaxon_1289549 a rdfs:Class ; rdfs:label "Coronavirus Mex_CoV-4" ; rdfs:subClassOf obo:NCBITaxon_366617 . a rdfs:Class ; rdfs:label "Conjunctivitis [Disease/Finding]" ; rdfs:subClassOf . obo:NCBITaxon_1429868 a rdfs:Class ; rdfs:label "Betacoronavirus H.sav/Italy/206645-40/2011" ; rdfs:subClassOf obo:NCBITaxon_696098 . a rdfs:Class ; rdfs:label "Cellular Activity Alteration [PE]" ; rdfs:subClassOf . obo:CIDO_0020064 a rdfs:Class ; rdfs:label "BIOTIME SARS-CoV-2 IgG/IgM Rapid Qualitative Test" ; rdfs:seeAlso ; rdfs:subClassOf obo:CIDO_0000454 . obo:NCBITaxon_1920891 a rdfs:Class ; rdfs:label "Bat alphacoronavirus/UF-FWC/2016/3" ; rdfs:subClassOf obo:NCBITaxon_366617 . a rdfs:Class ; rdfs:label "Protease Inhibitors [MoA]" ; rdfs:subClassOf . obo:NCBITaxon_264989 a rdfs:Class ; rdfs:label "SARS coronavirus cw049" ; rdfs:subClassOf obo:NCBITaxon_694009 . obo:CIDO_0000134 a rdfs:Class ; rdfs:label "coronavirus binding to host cell"@en ; rdfs:comment "A host-coronovirus interaction that involves in the coronavirus binding to a host cell" ; rdfs:subClassOf obo:CIDO_0000198 . obo:PR_P0DTC4 a rdfs:Class ; rdfs:label "envelope small membrane protein (SARS-CoV-2)" ; rdfs:comment "A protein that is a translation product of the E gene in SARS-CoV-2." ; rdfs:subClassOf obo:PR_000050262 . obo:PR_000006671 a rdfs:Class ; rdfs:label "protein dpy-19 1" ; rdfs:comment "A protein that is a translation product of the human DPY19L1 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:PR_000014557 a rdfs:Class ; rdfs:label "spliceosome-associated protein CWC27 homolog" ; rdfs:comment "A protein that is a translation product of the human CWC27 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:NCBITaxon_1503286 a rdfs:Class ; rdfs:label "BtMf-AlphaCoV/HuB2013" ; rdfs:subClassOf obo:NCBITaxon_694001 . obo:CHEBI_32679 a rdfs:Class ; rdfs:label "glutaminium" ; rdfs:comment "An alpha-amino-acid cation that is the conjugate acid of glutamine, arising from protonation of the amino group." ; rdfs:subClassOf obo:CHEBI_33719 . obo:DRON_00750866 a rdfs:Class ; rdfs:label "elbasvir" ; rdfs:subClassOf obo:OBI_0000047 . obo:PR_Q16513 a rdfs:Class ; rdfs:label "serine/threonine-protein kinase N2 (human)" ; rdfs:comment "A serine/threonine-protein kinase N2 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000012786 , obo:PR_000029067 . obo:HP_0000819 a rdfs:Class ; rdfs:label "Diabetes mellitus" ; rdfs:comment "A group of abnormalities characterized by hyperglycemia and glucose intolerance." ; rdfs:subClassOf obo:HP_0000818 , obo:HP_0012337 . obo:NCBITaxon_285949 a rdfs:Class ; rdfs:label "SARS coronavirus civet020" ; rdfs:subClassOf obo:NCBITaxon_694009 . obo:PR_P02745 a rdfs:Class ; rdfs:label "complement C1q subcomponent subunit A (human)" ; rdfs:comment "A complement C1q subcomponent subunit A that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000004875 , obo:PR_000029067 . obo:GO_0006811 a rdfs:Class ; rdfs:label "ion transport" ; rdfs:comment "The directed movement of charged atoms or small charged molecules into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." ; rdfs:subClassOf obo:GO_0006810 . obo:NCBITaxon_33511 a rdfs:Class ; rdfs:label "Deuterostomia" ; rdfs:subClassOf obo:NCBITaxon_33213 . a rdfs:Class ; rdfs:label "Enoplida Infections [Disease/Finding]" ; rdfs:subClassOf . obo:CHEBI_33429 a rdfs:Class ; rdfs:label "monoatomic monoanion" ; rdfs:subClassOf obo:CHEBI_23905 , obo:CHEBI_36830 . obo:NCBITaxon_2501962 a rdfs:Class ; rdfs:label "Rousettus bat coronavirus GCCDC1" ; rdfs:subClassOf obo:NCBITaxon_2509502 . obo:OAE_0000947 a rdfs:Class ; rdfs:label "hypoesthesia oral AE" ; rdfs:comment "a hypoaesthesia AE that has an outcome of a reduced sense of touch or sensation, or a partial loss of sensitivity to sensory stimuli in the oral area" ; rdfs:subClassOf obo:OAE_0000317 . obo:PR_P06493 a rdfs:Class ; rdfs:label "cyclin-dependent kinase 1 (human)" ; rdfs:comment "A cyclin-dependent kinase 1 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000003271 , obo:PR_000029067 . obo:PR_Q9Y375 a rdfs:Class ; rdfs:label "complex I intermediate-associated protein 30, mitochondrial (human)" ; rdfs:comment "A complex I intermediate-associated protein 30, mitochondrial that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000029067 , obo:PR_000031907 . obo:GO_0071870 a rdfs:Class ; rdfs:label "cellular response to catecholamine stimulus" ; rdfs:comment "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a catecholamine stimulus. A catecholamine is any of a group of biogenic amines that includes 4-(2-aminoethyl)pyrocatechol [4-(2-aminoethyl)benzene-1,2-diol] and derivatives formed by substitution." ; rdfs:subClassOf obo:GO_0071407 , obo:GO_0071868 , obo:GO_0071869 , obo:GO_1901701 . obo:GO_0043549 a rdfs:Class ; rdfs:label "regulation of kinase activity" ; rdfs:comment "Any process that modulates the frequency, rate or extent of kinase activity, the catalysis of the transfer of a phosphate group, usually from ATP, to a substrate molecule." ; rdfs:subClassOf obo:GO_0042325 , obo:GO_0051338 . obo:PR_000001780 a rdfs:Class ; rdfs:label "interleukin-1 receptor-associated kinase 4" ; rdfs:comment "A protein that is a translation product of the human IRAK4 gene or a 1:1 ortholog thereof. The archetypical form consists of an N-terminal Death domain (Pfam:PF00531) and a C-terminal Protein kinase domain (Pfam:PF00069). This protein is an essential component of innate immunity." ; rdfs:subClassOf obo:PR_000000001 . obo:CIDO_0020163 a rdfs:Class ; rdfs:label "GWU SARS-CoV-2 RT-PCR Test" ; rdfs:seeAlso ; rdfs:subClassOf obo:CIDO_0000454 . obo:PR_000005932 a rdfs:Class ; rdfs:label "granulocyte colony-stimulating factor" ; rdfs:comment "A protein that is a translation product of the human CSF3 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:CIDO_0020276 a rdfs:Class ; rdfs:label "SARS-CoV-2 PCR test" ; rdfs:seeAlso ; rdfs:subClassOf obo:CIDO_0000454 . obo:GO_0031294 a rdfs:Class ; rdfs:label "lymphocyte costimulation" ; rdfs:comment "The process of providing, via surface-bound receptor-ligand pairs, a second, antigen-independent, signal in addition to that provided by the B- or T cell receptor to augment B- or T cell activation." ; rdfs:subClassOf obo:GO_0002376 , obo:GO_0051251 . a rdfs:Class ; rdfs:label "G-Protein-linked Receptor Interactions [MoA]" ; rdfs:subClassOf . obo:CHEBI_26878 a rdfs:Class ; rdfs:label "tertiary alcohol" ; rdfs:comment "A tertiary alcohol is a compound in which a hydroxy group, -OH, is attached to a saturated carbon atom which has three other carbon atoms attached to it." ; rdfs:subClassOf obo:CHEBI_30879 . obo:CIDO_0000300 a rdfs:Class ; rdfs:label "coronavirus epitope"@en ; rdfs:subClassOf obo:OBI_1110001 . obo:CIDO_0020044 a rdfs:Class ; rdfs:label "BD Veritor System for Rapid Detection of SARS-CoV-2" ; rdfs:seeAlso ; rdfs:subClassOf obo:CIDO_0000454 . obo:CHEBI_25750 a rdfs:Class ; rdfs:label "oxime" ; rdfs:comment "Compounds of structure R2C=NOH derived from condensation of aldehydes or ketones with hydroxylamine. Oximes from aldehydes may be called aldoximes; those from ketones may be called ketoximes." ; rdfs:subClassOf obo:CHEBI_50860 , obo:CHEBI_51143 . obo:CIDO_0000985 a rdfs:Class ; rdfs:label "SARS-CoV2 orf7a protein binding to human MDN1" ; rdfs:comment "SARS-CoV2 orf7a protein binding to human MDN1, as evidented by an affinity-purification mass spectrometry experiment" ; rdfs:subClassOf obo:CIDO_0000587 . obo:OGG_3043740573 a rdfs:Class ; rdfs:label "ORF7a of severe acute respiratory syndrome coronavirus 2" ; rdfs:subClassOf obo:OGG_2002697049 . obo:PR_000011473 a rdfs:Class ; rdfs:label "NUAK family SNF1-like kinase 1" ; rdfs:comment "A protein that is a translation product of the human NUAK1 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:DOID_845 a rdfs:Class ; rdfs:label "cyclothymic disorder" ; rdfs:comment "A bipolar disorder that involves recurrent hypomanic and dysthymic episodes, but no full manic episodes or full major depressive episodes." ; rdfs:subClassOf obo:DOID_3312 . obo:CHEBI_5938 a rdfs:Class ; rdfs:label "Interferon beta-1b" ; rdfs:subClassOf obo:CHEBI_50860 . obo:CIDO_0000148 a rdf:Property ; rdfs:label "chemical modulates response in vitro against virus"@en ; rdfs:comment "An object property that represents a relation between a chemical entity and a virus where the chemical has an effective role in modulating host response against viral infection in vitro" ; rdfs:range ; rdfs:subPropertyOf obo:CIDO_0000146 , obo:CIDO_0000141 . obo:NCBITaxon_1788485 a rdfs:Class ; rdfs:label "Rhinolophus bat coronavirus BtCoV/3750" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:CHEBI_64600 a rdfs:Class ; rdfs:label "C21-steroid hormone" ; rdfs:comment "A steroid compound with a structure based on a 21-carbon (pregnane) skeleton that acts as a hormone." ; rdfs:subClassOf obo:CHEBI_26764 , obo:CHEBI_61313 . obo:CIDO_0000620 a rdfs:Class ; rdfs:label "P71L in SARS-CoV-2 E protein" ; rdfs:comment "An AA mutation or AA variant that has mutated an amino acid at position 71 into a leucine" ; rdfs:subClassOf obo:CIDO_0000598 . obo:OPMI_0000456 a rdfs:Class ; rdfs:label "prognostic biomarker"@en ; rdfs:comment "A biomarker that provides information about the patient's overall outcome, regardless of therapy." ; rdfs:subClassOf obo:OPMI_0000445 . obo:CHEBI_32656 a rdfs:Class ; rdfs:label "D-asparaginate" ; rdfs:subClassOf obo:CHEBI_32660 . obo:CHEBI_50337 a rdfs:Class ; rdfs:label "1H-indol-3-ylmethyl group" ; rdfs:subClassOf obo:CHEBI_50325 . obo:NCBITaxon_2509485 a rdfs:Class ; rdfs:label "Herdecovirus" ; rdfs:subClassOf obo:NCBITaxon_1159901 . obo:PR_000013589 a rdfs:Class ; rdfs:label "Ras-related protein Rab-18" ; rdfs:comment "A protein that is a translation product of the human RAB18 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:PR_000002312 a rdfs:Class ; rdfs:label "caspase-3" ; rdfs:comment "A caspase-3-like protease that is a translation product of the human CASP3 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000002196 . obo:NCBITaxon_2772455 a rdfs:Class ; rdfs:label "Erinaceus hedgehog coronavirus cw_6c" ; rdfs:subClassOf obo:NCBITaxon_696098 . obo:CHEBI_74529 a rdfs:Class ; rdfs:label "antidote to paracetamol poisoning" ; rdfs:comment "A role borne by a molecule that acts to counteract or neutralize the deleterious effects of paracetamol (acetaminophen)." ; rdfs:subClassOf obo:CHEBI_50247 . obo:PR_000003065 a rdfs:Class ; rdfs:label "tyrosine-protein kinase SYK" ; rdfs:comment "A SYK/ZAP-70 family tyrosine-protein kinase that is a translation product of the human SYK gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000003063 . obo:PR_000014870 a rdfs:Class ; rdfs:label "serine/threonine-protein kinase SIK1" ; rdfs:comment "A protein that is a translation product of the human SIK1 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:NCBITaxon_1415835 a rdfs:Class ; rdfs:label "Bat SARS-like coronavirus Rs3369" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:PR_000031752 a rdfs:Class ; rdfs:label "palmitoyltransferase ZDHHC5" ; rdfs:comment "A protein that is a translation product of the human ZDHHC5 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:PR_000003425 a rdfs:Class ; rdfs:label "Hsp70 family chaperone" ; rdfs:comment "A protein that is a stand alone version of the Hsp70 protein (Pfam:PF00012) domain, which comprises two major regions: an N-terminal ATP-binding domain and a C-terminal substrate-binding domain." ; rdfs:subClassOf obo:PR_000000001 . a rdfs:Class ; rdfs:label "Large Intestine Fluid/Electrolyte Absorption Alteration [PE]" ; rdfs:subClassOf . obo:PR_Q9HAV7 a rdfs:Class ; rdfs:label "GrpE protein homolog 1, mitochondrial (human)" ; rdfs:comment "A GrpE protein homolog 1, mitochondrial that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000008272 , obo:PR_000029067 . obo:VO_0005089 a rdfs:Class ; rdfs:label "GLS-5310"@en ; rdfs:comment "A SARS-CoV-2 plasmid DNA vaccine developed by GeneOne Life Science." ; rdfs:subClassOf obo:VO_0005203 . obo:PR_Q9Y6R4 a rdfs:Class ; rdfs:label "mitogen-activated protein kinase kinase kinase 4 (human)" ; rdfs:comment "A mitogen-activated protein kinase kinase kinase 4 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000010137 , obo:PR_000029067 . obo:PR_P48544 a rdfs:Class ; rdfs:label "G protein-activated inward rectifier potassium channel 4 (human)" ; rdfs:comment "A G protein-activated inward rectifier potassium channel 4 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000002005 , obo:PR_000029067 . obo:VO_0001107 a rdfs:Class ; rdfs:label "Modified Vaccinia Ankara (MVA) virus vaccine vector"@en ; rdfs:comment "a vaccinia virus vector that uses the Modified Vaccinia Ankara (MVA) virus. " ; rdfs:subClassOf obo:VO_0000600 . a rdfs:Class ; rdfs:label "Gastroenteritis [Disease/Finding]" ; rdfs:subClassOf . obo:PR_Q14789 a rdfs:Class ; rdfs:label "golgin subfamily B member 1 (human)" ; rdfs:comment "A golgin subfamily B member 1 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000008139 , obo:PR_000029067 . obo:NCBITaxon_422138 a rdfs:Class ; rdfs:label "Sable antelope coronavirus US/OH1/2003" ; rdfs:subClassOf obo:NCBITaxon_11128 . obo:NCBITaxon_482176 a rdfs:Class ; rdfs:label "Bat coronavirus DR/2007" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:PR_000003057 a rdfs:Class ; rdfs:label "conventional protein kinase C" ; rdfs:comment "A protein that is a member of the conventional phorbol ester (and diacylglycerol) receptor/protein kinase class. The canonical protein sequence has a core domain architecture consisting of two copies of the Phorbol esters/diacylglycerol binding domain (C1 domain) (Pfam:PF00130), followed by a C2 domain (Pfam:PF00168), a Protein kinase domain (Pfam:PF00069) and a Protein kinase C terminal domain (Pfam:PF00433)." ; rdfs:subClassOf obo:PR_000000001 . a rdfs:Class ; rdfs:label "Diseases, Manifestations or Physiologic States [Disease/Finding]" ; rdfs:subClassOf obo:BFO_0000016 . obo:CIDO_0000232 a rdfs:Class ; rdfs:label "SARS-CoV-2 clade G virus"@en ; rdfs:comment "A SARS-CoV-2 variant virus that has signature mutation in Spike D614G." ; rdfs:subClassOf obo:CIDO_0000405 . obo:CIDO_0000944 a rdfs:Class ; rdfs:label "SARS-CoV2 nsp8 protein binding to human SRP19" ; rdfs:comment "SARS-CoV2 nsp8 protein binding to human SRP19, as evidented by an affinity-purification mass spectrometry experiment" ; rdfs:subClassOf obo:CIDO_0000582 . obo:CHEBI_32872 a rdfs:Class ; rdfs:label "prolinium" ; rdfs:comment "An alpha-amino-acid cation that is the conjugate acid of proline, arising from protonation of the amino group." ; rdfs:subClassOf obo:CHEBI_33719 . obo:PR_000007125 a rdfs:Class ; rdfs:label "ephrin type-A receptor 5" ; rdfs:comment "An ephrin receptor that is a translation product of the human EPHA5 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000025845 . obo:CIDO_0000754 a rdfs:Class ; rdfs:label "SARS-CoV2 M protein binding to human COQ8B" ; rdfs:comment "SARS-CoV2 M protein binding to human COQ8B, as evidented by an affinity-purification mass spectrometry experiment" ; rdfs:subClassOf obo:CIDO_0000055 . obo:NCBITaxon_389162 a rdfs:Class ; rdfs:label "Bat coronavirus (BtCoV/A914/2005)" ; rdfs:subClassOf obo:NCBITaxon_389126 . obo:NCBITaxon_1288698 a rdfs:Class ; rdfs:label "Bat coronavirus POA/2012/E07" ; rdfs:subClassOf obo:NCBITaxon_366617 . obo:PR_000014284 a rdfs:Class ; rdfs:label "ribosomal protein S6 kinase alpha-3" ; rdfs:comment "A ribosomal protein S6 kinase alpha that is a translation product of the human RPS6KA3 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000029187 . a rdfs:Class ; rdfs:label "Vestibular Diseases [Disease/Finding]" ; rdfs:subClassOf . obo:DOID_0070087 a rdfs:Class ; rdfs:label "schizophrenia 11" ; rdfs:comment "A schizophrenia that has_material_basis_in a mutation on chromosome 10q22.3." ; rdfs:subClassOf obo:DOID_0050736 , obo:DOID_5419 . obo:CHEBI_87183 a rdfs:Class ; rdfs:label "STAT3 inhibitor" ; rdfs:comment "An inhibitor of signal transducer and activator of transcription 3 (STAT3)" ; rdfs:subClassOf obo:CHEBI_35222 , obo:CHEBI_52206 . obo:DOID_0081013 a rdfs:Class ; rdfs:label "severe COVID-19"@en ; rdfs:comment "A COVID-19 that is characterized by any of (1) Oxygen saturation < 90% on room air, (2) Respiratory rate > 30 breaths/min in adults and children > 5 years old, ≥ 60 breaths/min in children < 2 months old, ≥ 50 in children 2–11 months old, and ≥ 40 in children 1–5 years old, or (3) signs of severe respiratory distress (accessory muscle use, inability to complete full sentences, and, in children, very severe chest wall indrawing, grunting, central cyanosis, or presence of any other general danger signs." ; rdfs:subClassOf obo:DOID_0080600 . obo:PR_000029948 a rdfs:Class ; rdfs:label "glutathione S-transferase mu" ; rdfs:comment "Category=family. Note: Classification described in wikipedia. [Wikipedia:Glutathione_S-transferase]" ; rdfs:subClassOf obo:PR_000029945 . obo:PR_000014966 a rdfs:Class ; rdfs:label "chromaffin granule amine transporter" ; rdfs:comment "A protein that is a translation product of the human SLC18A1 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:CHEBI_32445 a rdfs:Class ; rdfs:label "L-cysteinium" ; rdfs:comment "The L-enantiomer of cysteinium." ; rdfs:subClassOf obo:CHEBI_32458 . obo:PR_000004994 a rdfs:Class ; rdfs:label "calcium/calmodulin-dependent protein kinase kinase 1" ; rdfs:comment "A protein that is a translation product of the human CAMKK1 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:CHEBI_36963 a rdfs:Class ; rdfs:label "organooxygen compound" ; rdfs:comment "An organochalcogen compound containing at least one carbon-oxygen bond." ; rdfs:subClassOf obo:CHEBI_25806 , obo:CHEBI_36962 . obo:HP_0002140 a rdfs:Class ; rdfs:label "Ischemic stroke" ; rdfs:comment "Acute ischemic stroke (AIS) is defined by the sudden loss of blood flow to an area of the brain with the resulting loss of neurologic function. It is caused by thrombosis or embolism that occludes a cerebral vessel supplying a specific area of the brain. During a vessel occlusion, there is a core area where damage to the brain is irreversible and an area of penumbra where the brain has lost function owing to decreased blood flow but is not irreversibly injured." ; rdfs:subClassOf obo:HP_0030163 , obo:HP_0100659 . obo:CHEBI_31397 a rdfs:Class ; rdfs:label "Ciclesonide" ; rdfs:subClassOf obo:CHEBI_50860 . obo:PR_P12104 a rdfs:Class ; rdfs:label "fatty acid-binding protein, intestinal (human)" ; rdfs:comment "A fatty acid-binding protein, intestinal that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000007310 , obo:PR_000029067 . obo:PR_P49642 a rdfs:Class ; rdfs:label "DNA primase small subunit (human)" ; rdfs:comment "A DNA primase small subunit that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000013215 , obo:PR_000029067 . a rdfs:Class ; rdfs:label "Gram-Negative Bacterial Infections [Disease/Finding]" ; rdfs:subClassOf . obo:CHEBI_33273 a rdfs:Class ; rdfs:label "polyatomic anion" ; rdfs:comment "An anion consisting of more than one atom." ; rdfs:subClassOf obo:CHEBI_22563 , obo:CHEBI_36358 . obo:NCBITaxon_2794341 a rdfs:Class ; rdfs:label "Montifringilla taczanowskii coronavirus HM" ; rdfs:subClassOf obo:NCBITaxon_1232736 . obo:NCBITaxon_1503297 a rdfs:Class ; rdfs:label "BtRf-BetaCoV/HeN2013" ; rdfs:subClassOf obo:NCBITaxon_366617 . obo:CHEBI_38104 a rdfs:Class ; rdfs:label "oxacycle" ; rdfs:comment "Any organic heterocyclic compound containing at least one ring oxygen atom." ; rdfs:subClassOf obo:CHEBI_24532 , obo:CHEBI_36963 . obo:PR_000003041 a rdfs:Class ; rdfs:label "serine/threonine-protein kinase mTOR" ; rdfs:comment "A protein that is a translation product of the human MTOR gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:CIDO_0020123 a rdfs:Class ; rdfs:label "DxTerity SARS-CoV-2 RT PCR CE Test" ; rdfs:seeAlso ; rdfs:subClassOf obo:CIDO_0000454 . obo:PR_000010125 a rdfs:Class ; rdfs:label "dual specificity mitogen-activated protein kinase kinase 1" ; rdfs:comment "A protein that is a translation product of the human MAP2K1 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:VO_0005207 a rdfs:Class ; rdfs:label "Advax vaccine adjuvant"@en ; rdfs:comment "A polysaccharide adjuvant derived from delta inulin" ; rdfs:subClassOf obo:VO_0001359 . obo:VO_0005312 a rdf:Property ; rdfs:label "induces immune profile"@en ; rdfs:comment "An object property that represents a relation between a material entity (such as vaccine or vaccine adjuvant) and an immune profile where the material entity can induce the immune profile in a host." ; rdfs:range . obo:NCBITaxon_1679877 a rdfs:Class ; rdfs:label "Coronavirus Hare_CoV/La06_382/Lep_gra/ESP/2006" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:NCBITaxon_235173 a rdfs:Class ; rdfs:label "SARS coronavirus Shanhgai LY" ; rdfs:subClassOf obo:NCBITaxon_694009 . obo:CHEBI_48559 a rdfs:Class ; rdfs:label "phenylindole" ; rdfs:subClassOf obo:CHEBI_24828 . obo:PR_P11274 a rdfs:Class ; rdfs:label "breakpoint cluster region protein (human)" ; rdfs:comment "A breakpoint cluster region protein that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000004712 , obo:PR_000029067 . obo:OPMI_0000582 a rdfs:Class ; rdfs:label "clnical measurement identifier"@en ; rdfs:comment "A unique key given to a Measurement record for a Person. Such record can be used in the ETL for how duplicate Measurements during the same Visit were handled." ; rdfs:subClassOf obo:IAO_0000578 . obo:CIDO_0020004 a rdfs:Class ; rdfs:label "Access SARS-CoV-2 IgM" ; rdfs:seeAlso ; rdfs:subClassOf obo:CIDO_0000454 . obo:DRON_00000011 a rdfs:Class ; rdfs:label "portion of cream"@en ; rdfs:comment "a portion of emulsion of oil and water in nearly equal proportions with high viscosity"@en ; rdfs:subClassOf obo:DRON_00000010 . obo:VO_0005120 a rdfs:Class ; rdfs:label "MERS England1 S DNA Vaccine" ; rdfs:comment "A MERS DNA vaccine made of the VRC8400 plasmid that encodes the full-length, membrane anchore MERS spike protein" ; rdfs:subClassOf obo:VO_0004900 . a rdfs:Class ; rdfs:label "Neuromuscular Junction Diseases [Disease/Finding]" ; rdfs:subClassOf . obo:GO_0046873 a rdfs:Class ; rdfs:label "metal ion transmembrane transporter activity" ; rdfs:comment "Enables the transfer of metal ions from one side of a membrane to the other." ; rdfs:subClassOf obo:GO_0022890 . obo:GO_0006139 a rdfs:Class ; rdfs:label "nucleobase-containing compound metabolic process" ; rdfs:comment "Any cellular metabolic process involving nucleobases, nucleosides, nucleotides and nucleic acids." ; rdfs:subClassOf obo:GO_0006725 , obo:GO_0034641 , obo:GO_0044238 , obo:GO_0046483 , obo:GO_1901360 . a rdfs:Class ; rdfs:label "Lipoxygenase Inhibitors [MoA]" ; rdfs:subClassOf . obo:PR_000007126 a rdfs:Class ; rdfs:label "ephrin type-A receptor 6" ; rdfs:comment "An ephrin receptor that is a translation product of the human EPHA6 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000025845 . obo:PR_Q08209 a rdfs:Class ; rdfs:label "serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform (human)" ; rdfs:comment "A serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000003278 , obo:PR_000029067 . obo:NCBITaxon_871681 a rdfs:Class ; rdfs:label "Feline coronavirus UU24" ; rdfs:subClassOf obo:NCBITaxon_12663 . obo:VO_0005350 a rdfs:Class ; rdfs:label "naNO-COVID"@en ; rdfs:comment "A SARS-CoV-2 subunit vaccine containing a T-cell priming specific cocktail of Coronaviruses peptides mounted on a gold nanoparticle." ; rdfs:subClassOf obo:VO_0005202 . obo:CIDO_0020180 a rdfs:Class ; rdfs:label "KPMAS COVID-19 Test" ; rdfs:seeAlso ; rdfs:subClassOf obo:CIDO_0000454 . obo:PATO_0001241 a rdfs:Class ; rdfs:label "physical object quality" ; rdfs:comment "A quality which inheres in a continuant." ; rdfs:subClassOf obo:BFO_0000019 . obo:PR_P0DTD3-1 a rdfs:Class ; rdfs:label "uncharacterized protein 14 (SARS-CoV-2)" ; rdfs:comment "An N gene translation product (SARS-CoV-2) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P0DTD3-1." ; rdfs:subClassOf obo:PR_000050387 . obo:NCBITaxon_424363 a rdfs:Class ; rdfs:label "Bat coronavirus HKU5-1" ; rdfs:subClassOf obo:NCBITaxon_694008 . obo:UBERON_0001062 a rdfs:Class ; rdfs:label "anatomical entity" ; rdfs:comment "Biological entity that is either an individual member of a biological species or constitutes the structural organization of an individual member of a biological species." ; rdfs:subClassOf obo:BFO_0000004 , obo:BFO_0000040 . obo:OPMI_0000536 a rdfs:Class ; rdfs:label "confirmed diagnosis status"@en ; rdfs:subClassOf obo:OPMI_0000533 . obo:CIDO_0000531 a rdfs:Class ; rdfs:label "SQLVEYGSFCDNINA" ; rdfs:comment "A coronavirus epitope that is part of some S protein from HCoV OC43 composed of the following amino acids SQLVEYGSFCDNINA" ; rdfs:subClassOf obo:CIDO_0000452 . obo:NCBITaxon_267386 a rdfs:Class ; rdfs:label "SARS coronavirus Sin3765V" ; rdfs:subClassOf obo:NCBITaxon_694009 . obo:DRON_00021290 a rdfs:Class ; rdfs:label "Chlorpromazine Extended Release Capsule" ; rdfs:subClassOf obo:DRON_00000026 . obo:PR_O76061 a rdfs:Class ; rdfs:label "stanniocalcin-2 (human)" ; rdfs:comment "A stanniocalcin-2 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000015729 , obo:PR_000029067 . obo:GO_0048870 a rdfs:Class ; rdfs:label "cell motility" ; rdfs:comment "Any process involved in the controlled self-propelled movement of a cell that results in translocation of the cell from one place to another." ; rdfs:subClassOf obo:GO_0008150 , obo:GO_0009987 . obo:PR_P61970 a rdfs:Class ; rdfs:label "nuclear transport factor 2 (human)" ; rdfs:comment "A nuclear transport factor 2 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000011533 , obo:PR_000029067 . obo:PR_P62508 a rdfs:Class ; rdfs:label "estrogen-related receptor gamma (human)" ; rdfs:comment "An estrogen-related receptor gamma that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000007210 , obo:PR_000029067 . a rdfs:Class ; rdfs:label "Renal/Urological Activity Alteration [PE]" ; rdfs:subClassOf . obo:CHEBI_24866 a rdfs:Class ; rdfs:label "salt" ; rdfs:comment "A salt is an assembly of cations and anions." ; rdfs:subClassOf obo:CHEBI_37577 . a rdfs:Class ; rdfs:label "Echinocandins [Chemical/Ingredient]" ; rdfs:subClassOf . obo:CIDO_0000765 a rdfs:Class ; rdfs:label "SARS-CoV2 M protein binding to human REEP6" ; rdfs:comment "SARS-CoV2 M protein binding to human REEP6, as evidented by an affinity-purification mass spectrometry experiment" ; rdfs:subClassOf obo:CIDO_0000055 . a rdfs:Class ; rdfs:label "Proteostasis Deficiencies [Disease/Finding]" ; rdfs:subClassOf . obo:CIDO_0001084 a rdfs:Class ; rdfs:label "AA variant in SARS-CoV-2 nsp13 protein"@en ; rdfs:comment "An AA variant in SARS-CoV-2 nsp13 protein. Equivalent to an AA variant in SARS-CoV-2 rep 1ab with an AA position of 5302 - 5902." ; rdfs:subClassOf obo:CIDO_0000715 . obo:CIDO_0020175 a rdfs:Class ; rdfs:label "Innovita 2019-nCoV Ab Test (Colloidal Gold)" ; rdfs:seeAlso ; rdfs:subClassOf obo:CIDO_0000454 . obo:PR_000007940 a rdfs:Class ; rdfs:label "FAD-linked sulfhydryl oxidase ALR" ; rdfs:comment "A protein that is a translation product of the human GFER gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:PR_P10275 a rdfs:Class ; rdfs:label "androgen receptor (human)" ; rdfs:comment "An androgen receptor that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000004191 , obo:PR_000029067 . obo:PR_000014204 a rdfs:Class ; rdfs:label "60S ribosomal protein L23a" ; rdfs:comment "A protein that is a translation product of the human RPL23A gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:PR_Q9UM73 a rdfs:Class ; rdfs:label "ALK tyrosine kinase receptor (human)" ; rdfs:comment "An ALK tyrosine kinase receptor that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000001282 , obo:PR_000029067 . obo:NCBITaxon_749436 a rdfs:Class ; rdfs:label "Rock sandpiper coronavirus CIR-65885" ; rdfs:subClassOf obo:NCBITaxon_749416 . obo:CIDO_0000709 a rdfs:Class ; rdfs:label "F888L in SARS-CoV-2 S protein"@en ; rdfs:comment "An AA mutation or AA variant that has mutated an amino acid at position 888 into a leucine in S protein." ; rdfs:subClassOf obo:CIDO_0000595 . obo:GO_0042127 a rdfs:Class ; rdfs:label "regulation of cell population proliferation" ; rdfs:comment "Any process that modulates the frequency, rate or extent of cell proliferation." ; rdfs:subClassOf obo:GO_0050794 . obo:CIDO_0001128 a rdfs:Class ; rdfs:label "SARS-CoV2 orf8 protein binding to human PLD3"@en ; rdfs:comment "SARS-CoV2 orf8 protein binding to human PLD3, as evidented by an affinity-purification mass spectrometry experiment" ; rdfs:subClassOf obo:CIDO_0000051 . obo:PR_O75439 a rdfs:Class ; rdfs:label "mitochondrial-processing peptidase subunit beta (human)" ; rdfs:comment "A mitochondrial-processing peptidase subunit beta that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000012912 , obo:PR_000029067 . obo:GO_0045429 a rdfs:Class ; rdfs:label "positive regulation of nitric oxide biosynthetic process" ; rdfs:comment "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of nitric oxide." ; rdfs:subClassOf obo:GO_0031328 , obo:GO_0045428 , obo:GO_1904407 . obo:NCBITaxon_33736 a rdfs:Class ; rdfs:label "Porcine respiratory coronavirus (strain 86/137004 / British isolate)" ; rdfs:subClassOf obo:NCBITaxon_11146 . obo:NCBITaxon_903624 a rdfs:Class ; rdfs:label "Kenya bat coronavirus BtKY86" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:GO_0001662 a rdfs:Class ; rdfs:label "behavioral fear response" ; rdfs:comment "An acute behavioral change resulting from a perceived external threat." ; rdfs:subClassOf obo:GO_0002209 , obo:GO_0033555 . obo:CHEBI_46883 a rdfs:Class ; rdfs:label "carboxy group" ; rdfs:subClassOf obo:CHEBI_33249 . obo:CHEBI_38131 a rdfs:Class ; rdfs:label "lactol" ; rdfs:comment "Cyclic hemiacetals formed by intramolecular addition of a hydroxy group to an aldehydic or ketonic carbonyl group. They are thus 1-oxacycloalkan-2-ols or unsaturated analogues." ; rdfs:subClassOf obo:CHEBI_5653 . obo:PR_000003386 a rdfs:Class ; rdfs:label "collagen type VI alpha chain" ; rdfs:comment "A collagen alpha chain that is a translation product of the human COL6A1, COL6A2, or COL6A3 genes, 1:1 orthologs thereof, or a semi-ortholog thereof." ; rdfs:subClassOf obo:PR_000003262 . obo:CIDO_0020293 a rdfs:Class ; rdfs:label "Simoa Semi-Quantitative SARS-CoV-2 IgG Antibody Test" ; rdfs:seeAlso ; rdfs:subClassOf obo:CIDO_0000454 . obo:NCBITaxon_1146852 a rdfs:Class ; rdfs:label "Bat coronavirus M.nattereri/UK/Sav/1088A" ; rdfs:subClassOf obo:NCBITaxon_366617 . obo:CIDO_0000463 a rdfs:Class ; rdfs:label "APYGLYFIHFSYVPT" ; rdfs:comment "A coronavirus epitope that is part of some S protein from HCoV OC43 composed of the following amino acids APYGLYFIHFSYVPT" ; rdfs:subClassOf obo:CIDO_0000452 . obo:PR_Q9BXA7 a rdfs:Class ; rdfs:label "testis-specific serine/threonine-protein kinase 1 (human)" ; rdfs:comment "A testis-specific serine/threonine-protein kinase 1 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000016770 , obo:PR_000029067 . obo:PR_000016862 a rdfs:Class ; rdfs:label "endoplasmic reticulum resident protein 44" ; rdfs:comment "A protein that is a translation product of the human ERP44 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:CIDO_0000748 a rdfs:Class ; rdfs:label "SARS-CoV2 M protein binding to human ACADM" ; rdfs:comment "SARS-CoV2 M protein binding to human ACADM, as evidented by an affinity-purification mass spectrometry experiment" ; rdfs:subClassOf obo:CIDO_0000055 . obo:PR_000010628 a rdfs:Class ; rdfs:label "28S ribosomal protein S2, mitochondrial" ; rdfs:comment "A protein that is a translation product of the human MRPS2 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:CIDO_0000004 a rdfs:Class ; rdfs:label "MERS-CoV disease process"@en ; rdfs:subClassOf obo:CIDO_0000001 . obo:PR_000012423 a rdfs:Class ; rdfs:label "pericentrin" ; rdfs:comment "A protein that is a translation product of the human PCNT gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:CIDO_0020056 a rdfs:Class ; rdfs:label "BioFire Respiratory Panel 2.1-EZ (RP2.1-EZ)" ; rdfs:seeAlso ; rdfs:subClassOf obo:CIDO_0000454 . obo:CHEBI_55373 a rdfs:Class ; rdfs:label "isoxazoles" ; rdfs:comment "Oxazoles in which the N and O atoms are adjacent." ; rdfs:subClassOf obo:CHEBI_35790 . obo:NCBITaxon_669514 a rdfs:Class ; rdfs:label "Bat coronavirus SLO1A0082/2008/SVN" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:CHEBI_38165 a rdfs:Class ; rdfs:label "organic heterooctacyclic compound" ; rdfs:subClassOf obo:CHEBI_38166 . obo:PR_000008682 a rdfs:Class ; rdfs:label "protein Hook homolog 1" ; rdfs:comment "A protein that is a translation product of the human HOOK1 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:CHEBI_189664 a rdfs:Class ; rdfs:label "benzofuropyrimidine" ; rdfs:comment "An organic heterotricyclic compound in which pyrmidine is ortho-fused to a bicyclic benzofuran ring." ; rdfs:subClassOf obo:CHEBI_26979 , obo:CHEBI_38101 , obo:CHEBI_38104 . obo:PR_Q14164 a rdfs:Class ; rdfs:label "inhibitor of nuclear factor kappa-B kinase subunit epsilon (human)" ; rdfs:comment "An inhibitor of nuclear factor kappa-B kinase subunit epsilon that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000001778 , obo:PR_000029067 . a rdfs:Class ; rdfs:label "Herpes Simplex [Disease/Finding]" ; rdfs:subClassOf , . obo:IDO_0000497 a rdfs:Class ; rdfs:label "immunization against infectious agent"@en ; rdfs:comment "A process by which an organism acquires immunity to an infectious agent."@en ; rdfs:subClassOf obo:BFO_0000015 . obo:CIDO_0020247 a rdfs:Class ; rdfs:label "qSanger-COVID-19 Assay" ; rdfs:seeAlso ; rdfs:subClassOf obo:CIDO_0000454 . obo:UBERON_0001797 a rdfs:Class ; rdfs:label "vitreous humor" ; rdfs:comment "A transparent, semigelatinous substance that fills the cavity behind the crystalline lens of the eye and in front of the retina" ; rdfs:subClassOf obo:UBERON_0000463 . a rdfs:Class ; rdfs:label "Pre-Excitation Syndromes [Disease/Finding]" ; rdfs:subClassOf . obo:PR_O94804 a rdfs:Class ; rdfs:label "serine/threonine-protein kinase 10 (human)" ; rdfs:comment "A serine/threonine-protein kinase 10 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000015739 , obo:PR_000029067 . obo:OBI_0002552 a rdfs:Class ; rdfs:label "testis specimen" ; rdfs:comment "A specimen that is derived from testis." ; rdfs:subClassOf obo:OBI_0001479 . a rdfs:Class ; rdfs:label "Interferon Type I [Chemical/Ingredient]" ; rdfs:subClassOf . obo:CIDO_0000235 a rdfs:Class ; rdfs:label "SARS-CoV-2 clade GR virus"@en ; rdfs:comment "A SARS-CoV-2 clade G variant virus that carries the combination of Spike D614G and Nucleocapsid RG203KR mutations." ; rdfs:subClassOf obo:CIDO_0000232 . obo:GO_0140352 a rdfs:Class ; rdfs:label "export from cell" ; rdfs:comment "The directed movement of some substance from a cell, into the extracellular region. This may occur via transport across the plasma membrane or via exocytosis." ; rdfs:subClassOf obo:GO_0006810 , obo:GO_0009987 . obo:DRON_00019082 a rdfs:Class ; rdfs:label "ciclesonide" ; rdfs:subClassOf obo:OBI_0000047 . obo:CHEBI_17196 a rdfs:Class ; rdfs:label "L-asparagine" ; rdfs:comment "An optically active form of asparagine having L-configuration." ; rdfs:subClassOf obo:CHEBI_15705 , obo:CHEBI_22653 , obo:CHEBI_22658 , obo:CHEBI_83813 . obo:NCBITaxon_2691594 a rdfs:Class ; rdfs:label "unclassified Rhinacovirus" ; rdfs:subClassOf obo:NCBITaxon_2509509 . obo:CIDO_0000564 a rdfs:Class ; rdfs:label "VWHAKDFNSLSAEGR" ; rdfs:comment "A coronavirus epitope that is part of some S protein from HCoV 229E composed of the following amino acids VWHAKDFNSLSAEGR" ; rdfs:subClassOf obo:CIDO_0000451 . obo:NCBITaxon_37028 a rdfs:Class ; rdfs:label "Prionailurus" ; rdfs:subClassOf obo:NCBITaxon_338152 . obo:PR_Q8TEQ8 a rdfs:Class ; rdfs:label "GPI ethanolamine phosphate transferase 3 (human)" ; rdfs:comment "A GPI ethanolamine phosphate transferase 3 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000012702 , obo:PR_000029067 . obo:CHEBI_24315 a rdfs:Class ; rdfs:label "glutamic acid derivative" ; rdfs:comment "An amino acid derivative resulting from reaction of glutamic acid at the amino group or either of the carboxy groups, or from the replacement of any hydrogen by a heteroatom. The definition normally excludes peptides containing glutamic acid residues." ; rdfs:subClassOf obo:CHEBI_83821 . obo:CIDO_0000445 a rdfs:Class ; rdfs:label "surface glycoprotein (HCoV 229E)"@en ; rdfs:comment "A surface glycoprotein of human coronavirus 229E." ; rdfs:subClassOf obo:CIDO_0000444 . obo:PR_000013799 a rdfs:Class ; rdfs:label "RNA-binding protein 41" ; rdfs:comment "A protein that is a translation product of the human RBM41 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:HP_0011693 a rdfs:Class ; rdfs:label "Supraventricular tachycardia with a concealed accessory pathway on the septum" ; rdfs:subClassOf obo:HP_0011689 . obo:NCBITaxon_694006 a rdfs:Class ; rdfs:label "Rousettus bat coronavirus HKU9" ; rdfs:subClassOf obo:NCBITaxon_2509502 . obo:PR_O09807 a rdfs:Class ; rdfs:subClassOf obo:PR_000000001 . obo:CHEBI_64769 a rdfs:Class ; rdfs:label "organic cationic group" ; rdfs:comment "A cationic group that contains carbon." ; rdfs:subClassOf obo:CHEBI_64766 . obo:CIDO_0020322 a rdfs:Class ; rdfs:label "VIDAS SARS-CoV-2 IgM" ; rdfs:seeAlso ; rdfs:subClassOf obo:CIDO_0000454 . obo:CIDO_0000452 a rdfs:Class ; rdfs:label "HCoV OC43 S protein epitope"@en ; rdfs:subClassOf obo:CIDO_0000409 . obo:CHEBI_29967 a rdfs:Class ; rdfs:label "L-lysine residue" ; rdfs:subClassOf obo:CHEBI_32568 , obo:CHEBI_33700 , obo:CHEBI_83228 . obo:PR_P62072 a rdfs:Class ; rdfs:label "mitochondrial import inner membrane translocase subunit Tim10 (human)" ; rdfs:comment "A mitochondrial import inner membrane translocase subunit Tim10 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000016341 , obo:PR_000029067 . obo:PR_Q5VT06 a rdfs:Class ; rdfs:label "centrosome-associated protein 350 (human)" ; rdfs:comment "A centrosome-associated protein 350 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000005350 , obo:PR_000029067 . obo:CHEBI_138090 a rdfs:Class ; rdfs:label "ATPase motor cytoplasmic dynein inhibitor" ; rdfs:comment "Any inhibitor of ATPase motor cytoplasmic dynein." ; rdfs:subClassOf obo:CHEBI_35222 , obo:CHEBI_52206 . obo:NCBITaxon_511429 a rdfs:Class ; rdfs:label "SARS coronavirus BJ182-12" ; rdfs:subClassOf obo:NCBITaxon_694009 . obo:GO_0043603 a rdfs:Class ; rdfs:label "cellular amide metabolic process" ; rdfs:comment "The chemical reactions and pathways involving an amide, any derivative of an oxoacid in which an acidic hydroxy group has been replaced by an amino or substituted amino group, as carried out by individual cells." ; rdfs:subClassOf obo:GO_0034641 . obo:NCBITaxon_903591 a rdfs:Class ; rdfs:label "Kenya bat coronavirus BtKY53" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:CIDO_0000788 a rdfs:Class ; rdfs:label "SARS-CoV2 N protein binding to human RRP9" ; rdfs:comment "SARS-CoV2 N protein binding to human RRP9, as evidented by an affinity-purification mass spectrometry experiment" ; rdfs:subClassOf obo:CIDO_0000056 . obo:CHEBI_17561 a rdfs:Class ; rdfs:label "L-cysteine" ; rdfs:comment "An optically active form of cysteine having L-configuration." ; rdfs:subClassOf obo:CHEBI_15356 , obo:CHEBI_15705 , obo:CHEBI_26650 , obo:CHEBI_83813 . obo:NCBITaxon_267393 a rdfs:Class ; rdfs:label "SARS coronavirus SinP4" ; rdfs:subClassOf obo:NCBITaxon_694009 . obo:HP_0001645 a rdfs:Class ; rdfs:label "Sudden cardiac death" ; rdfs:comment "The heart suddenly and unexpectedly stops beating resulting in death within a short time period (generally within 1 h of symptom onset)." ; rdfs:subClassOf obo:HP_0001695 , obo:HP_0025142 . obo:CHEBI_33465 a rdfs:Class ; rdfs:label "elemental pnictogen" ; rdfs:subClassOf obo:CHEBI_24835 , obo:CHEBI_33259 , obo:CHEBI_33302 . obo:CIDO_0000884 a rdfs:Class ; rdfs:label "SARS-CoV2 nsp5 protein binding to human HDAC2" ; rdfs:comment "host-SARS-CoV2 protein-protein interaction where the SARS-CoV-2 nsp5 protein binds to human HDAC2, which is evidented by an affinity-purification mass spectrometry experiment." ; rdfs:subClassOf obo:CIDO_0000047 . obo:NCBITaxon_2042574 a rdfs:Class ; rdfs:label "Coronavirus PREDICT CoV-48" ; rdfs:subClassOf obo:NCBITaxon_366617 . obo:OPMI_0000522 a rdfs:Class ; rdfs:label "provenance of observation record"@en ; rdfs:comment "A provenance of record that determines the provenance of the Observation record, as in whether the measurement was from an EHR system, insurance claim, registry, or other sources." ; rdfs:subClassOf obo:OPMI_0000512 . obo:PR_P21802 a rdfs:Class ; rdfs:label "fibroblast growth factor receptor 2 (human)" ; rdfs:comment "A fibroblast growth factor receptor 2 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000001449 , obo:PR_000029067 . a rdfs:Class ; rdfs:label "M [Preparations]" ; rdfs:subClassOf . obo:NCBITaxon_10066 a rdfs:Class ; rdfs:label "Muridae" ; rdfs:subClassOf obo:NCBITaxon_337687 . a rdfs:Class ; rdfs:label "Central Nervous System Activity Alteration [PE]" ; rdfs:subClassOf . obo:PR_000030314 a rdfs:Class ; rdfs:label "protein FAM98A" ; rdfs:comment "A protein that is a translation product of the human FAM98A gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . a rdfs:Class ; rdfs:label "NELFINAVIR" ; rdfs:subClassOf . obo:CIDO_0000843 a rdfs:Class ; rdfs:label "SARS-CoV2 nsp13 protein binding to human GORASP1" ; rdfs:comment "SARS-CoV2 nsp13 protein binding to human GORASP1, as evidented by an affinity-purification mass spectrometry experiment" ; rdfs:subClassOf obo:CIDO_0000058 . obo:CHEBI_36828 a rdfs:Class ; rdfs:label "pseudohalide anion" ; rdfs:subClassOf obo:CHEBI_36829 . obo:CIDO_0020275 a rdfs:Class ; rdfs:label "SARS-CoV-2 NGS Assay" ; rdfs:seeAlso ; rdfs:subClassOf obo:CIDO_0000454 . obo:CIDO_0000319 a rdfs:Class ; rdfs:label "TRFQTLLALHRSYLT"@en ; rdfs:subClassOf obo:CIDO_0000314 . obo:CHEBI_13759 a rdfs:Class ; rdfs:label "alkylamine" ; rdfs:comment "Any primary amine in which the substituent attached to nitrogen is an alkyl group." ; rdfs:subClassOf obo:CHEBI_32877 . obo:PR_Q9H3Y6 a rdfs:Class ; rdfs:label "tyrosine-protein kinase Srms (human)" ; rdfs:comment "A tyrosine-protein kinase Srms that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000015622 , obo:PR_000029067 . obo:NCBITaxon_327279 a rdfs:Class ; rdfs:label "Bat coronavirus ZS-2005" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:OBCS_0000214 a rdfs:Class ; rdfs:label "sensitivity disposition"@en ; rdfs:comment "A disposition that inheres in a population of continuant and is realized in a test process (e.g., disease diagnosis)." ; rdfs:subClassOf obo:BFO_0000016 . obo:PR_P14416 a rdfs:Class ; rdfs:label "D(2) dopamine receptor (human)" ; rdfs:comment "A D(2) dopamine receptor that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000001177 , obo:PR_000029067 . obo:OMRSE_00000030 a rdfs:Class ; rdfs:label "human patient role"@en ; rdfs:comment "A patient role that inheres in a human being."@en ; rdfs:subClassOf obo:OMRSE_00000011 . a rdfs:Class ; rdfs:label "Porphyria, Acute Intermittent [Disease/Finding]" ; rdfs:subClassOf . obo:CHEBI_16243 a rdfs:Class ; rdfs:label "quercetin" ; rdfs:comment "A pentahydroxyflavone having the five hydroxy groups placed at the 3-, 3'-, 4'-, 5- and 7-positions. It is one of the most abundant flavonoids in edible vegetables, fruit and wine." ; rdfs:subClassOf obo:CHEBI_25883 , obo:CHEBI_52267 . obo:OAE_0000382 a rdfs:Class ; rdfs:label "asthenia AE" ; rdfs:comment "a muscle adverse event which has an outcome of asthenia, which is a medical term denoting symptoms of physical weakness and loss of strength." ; rdfs:subClassOf obo:OAE_0000435 . a rdfs:Class ; rdfs:label "Panic Disorder [Disease/Finding]" ; rdfs:subClassOf . obo:GO_0042981 a rdfs:Class ; rdfs:label "regulation of apoptotic process" ; rdfs:comment "Any process that modulates the occurrence or rate of cell death by apoptotic process." ; rdfs:subClassOf obo:GO_0043067 . a rdfs:Class ; rdfs:label "Hemorrhage [Disease/Finding]" ; rdfs:subClassOf . obo:NCBITaxon_903623 a rdfs:Class ; rdfs:label "Kenya bat coronavirus BtKY85" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:CHEBI_189653 a rdfs:Class ; rdfs:label "pelabresib" ; rdfs:comment "An organic heterotricyclic compound that is 4H-[1,2]oxazolo[5,4-d][2]benzazepine substituted by methyl, 2-amino-2-oxoethyl, and 4-chlorophenyl groups at positions 1, 4S and 6, respectively. It is a small molecule inhibitor of bromodomain and extra-terminal (BET) proteins and exhibits antineoplastic activity." ; rdfs:subClassOf obo:CHEBI_140324 , obo:CHEBI_26979 , obo:CHEBI_83403 . obo:OPMI_0000571 a rdfs:Class ; rdfs:label "drug exposure verbatim end date"@en ; rdfs:comment "The end date of a drug exposure as it appears in the source data" ; rdfs:subClassOf obo:OPMI_0000564 . a rdfs:Class ; rdfs:label "Nelfinavir [Chemical/Ingredient]" ; rdfs:subClassOf . obo:NCBITaxon_2042551 a rdfs:Class ; rdfs:label "Coronavirus PREDICT CoV-24" ; rdfs:subClassOf obo:NCBITaxon_696098 . obo:CIDO_0000724 a rdfs:Class ; rdfs:label "D2980N in SARS-CoV-2 pp1a protein"@en ; rdfs:comment "An AA variant that has mutated an amino acid at position 2980 into an arginine" ; rdfs:subClassOf obo:CIDO_0001073 . obo:PR_Q04912 a rdfs:Class ; rdfs:label "macrophage-stimulating protein receptor (human)" ; rdfs:comment "A macrophage-stimulating protein receptor that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000002063 , obo:PR_000029067 . obo:CHEBI_33670 a rdfs:Class ; rdfs:label "heteromonocyclic compound" ; rdfs:subClassOf obo:CHEBI_33661 , obo:CHEBI_5686 . obo:GO_0051580 a rdfs:Class ; rdfs:label "regulation of neurotransmitter uptake" ; rdfs:comment "Any process that modulates the frequency, rate or extent of the directed movement of a neurotransmitter into a neuron or glial cell." ; rdfs:subClassOf obo:GO_0051049 , obo:GO_0065008 . obo:OAE_0000601 a rdfs:Class ; rdfs:label "vomiting AE" ; rdfs:comment "an abnormal digestion AE which has an outcome of vomiting, the retrograde expulsion of gastric contents through the oral cavity"@en ; rdfs:subClassOf obo:OAE_0000554 . obo:NCBITaxon_2042563 a rdfs:Class ; rdfs:label "Coronavirus PREDICT CoV-38" ; rdfs:subClassOf obo:NCBITaxon_366617 . obo:CIDO_0000890 a rdfs:Class ; rdfs:label "SARS-CoV2 nsp6 protein binding to human SIGMAR1" ; rdfs:comment "SARS-CoV2 nsp6 protein binding to human SIGMAR1, as evidented by an affinity-purification mass spectrometry experiment" ; rdfs:subClassOf obo:CIDO_0000048 . obo:PR_Q9BQS8 a rdfs:Class ; rdfs:label "FYVE and coiled-coil domain-containing protein 1 (human)" ; rdfs:comment "A FYVE and coiled-coil domain-containing protein 1 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000029067 , obo:PR_000029502 . obo:CHEBI_30762 a rdfs:Class ; rdfs:label "salicylate" ; rdfs:comment "A monohydroxybenzoate that is the conjugate base of salicylic acid." ; rdfs:subClassOf obo:CHEBI_25388 . obo:CHEBI_32628 a rdfs:Class ; rdfs:label "leucinium" ; rdfs:comment "An alpha-amino-acid cation that is the conjugate acid of leucine, arising from protonation of the amino group." ; rdfs:subClassOf obo:CHEBI_33719 . obo:GO_0002019 a rdfs:Class ; rdfs:label "regulation of renal output by angiotensin" ; rdfs:comment "The process in which angiotensin directly modulates the rate of urine output by the kidney." ; rdfs:subClassOf obo:GO_0002016 . a rdfs:Class ; rdfs:label "Neoplasms, Ductal, Lobular, and Medullary [Disease/Finding]" ; rdfs:subClassOf . a rdfs:Class ; rdfs:label "Dihydroergotamine [Chemical/Ingredient]" ; rdfs:subClassOf . obo:GO_0019058 a rdfs:Class ; rdfs:label "viral life cycle" ; rdfs:comment "A set of processes which all viruses follow to ensure survival; includes attachment and entry of the virus particle, decoding of genome information, translation of viral mRNA by host ribosomes, genome replication, and assembly and release of viral particles containing the genome." ; rdfs:subClassOf obo:GO_0016032 . obo:PR_000001939 a rdfs:Class ; rdfs:label "thrombopoietin receptor" ; rdfs:comment "A protein that is a translation product of the human MPL gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:NCBITaxon_389242 a rdfs:Class ; rdfs:label "Bat coronavirus (BtCoV/367A/2005)" ; rdfs:subClassOf obo:NCBITaxon_389126 . obo:NCBITaxon_33735 a rdfs:Class ; rdfs:label "Murine hepatitis virus strain JHMV / variant CL-2" ; rdfs:subClassOf obo:NCBITaxon_11138 . obo:PR_000029676 a rdfs:Class ; rdfs:label "pleckstrin homology domain-containing family F member 2" ; rdfs:comment "A protein that is a translation product of the human PLEKHF2 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:PR_Q9UKA9 a rdfs:Class ; rdfs:label "polypyrimidine tract-binding protein 2 (human)" ; rdfs:comment "A polypyrimidine tract-binding protein 2 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000013411 , obo:PR_000029067 . obo:PR_P69905 a rdfs:Class ; rdfs:label "hemoglobin subunit alpha (human)" ; rdfs:comment "A hemoglobin subunit alpha that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000008456 , obo:PR_000029067 . obo:CIDO_0001157 a rdfs:Class ; rdfs:label "AA variant in SARS-CoV-2 S protein RBM region"@en ; rdfs:subClassOf obo:CIDO_0000593 . obo:NCBITaxon_231424 a rdfs:Class ; rdfs:label "Avian infectious bronchitis virus (strain H120)" ; rdfs:subClassOf obo:NCBITaxon_11120 . obo:NCBITaxon_473588 a rdfs:Class ; rdfs:label "Bovine coronavirus Bubalus/Italy/179/07-11" ; rdfs:subClassOf obo:NCBITaxon_11128 . obo:NCBITaxon_1076426 a rdfs:Class ; rdfs:label "Alphacoronavirus H.sav/L/Spain/2007" ; rdfs:subClassOf obo:NCBITaxon_366617 . obo:CHEBI_16857 a rdfs:Class ; rdfs:label "L-threonine" ; rdfs:comment "An optically active form of threonine having L-configuration." ; rdfs:subClassOf obo:CHEBI_15705 , obo:CHEBI_22658 , obo:CHEBI_26986 , obo:CHEBI_83813 . obo:CHEBI_71300 a rdfs:Class ; rdfs:label "EC 2.* (transferase) inhibitor" ; rdfs:comment "An enzyme inhibitor that inhibits the action of a transferase (EC 2.*)" ; rdfs:subClassOf obo:CHEBI_23924 . obo:CHEBI_75771 a rdfs:Class ; rdfs:label "mouse metabolite" ; rdfs:comment "Any mammalian metabolite produced during a metabolic reaction in a mouse (Mus musculus)." ; rdfs:subClassOf obo:CHEBI_75768 . obo:CHEBI_64570 a rdfs:Class ; rdfs:label "EC 2.1.2.1 (glycine hydroxymethyltransferase) inhibitor" ; rdfs:comment "An EC 2.1.2.* (hydroxymethyl-, formyl- and related transferases) inhibitor that interferes with the action of glycine hydroxymethyltransferase (EC 2.1.2.1)." ; rdfs:subClassOf obo:CHEBI_76874 . obo:CHEBI_61336 a rdfs:Class ; rdfs:label "C4-dicarboxylate" ; rdfs:comment "A dicarboxylate that contains four carbon atoms." ; rdfs:subClassOf obo:CHEBI_28965 . obo:GO_0030168 a rdfs:Class ; rdfs:label "platelet activation" ; rdfs:comment "A series of progressive, overlapping events triggered by exposure of the platelets to subendothelial tissue. These events include shape change, adhesiveness, aggregation, and release reactions. When carried through to completion, these events lead to the formation of a stable hemostatic plug." ; rdfs:subClassOf obo:GO_0001775 . obo:CHEBI_16398 a rdfs:Class ; rdfs:label "D-threonine" ; rdfs:comment "An optically active form of threonine having D-configuration." ; rdfs:subClassOf obo:CHEBI_16733 , obo:CHEBI_26986 . obo:CIDO_0000830 a rdfs:Class ; rdfs:label "SARS-CoV2 nsp13 protein binding to human CEP350" ; rdfs:comment "SARS-CoV2 nsp13 protein binding to human CEP350, as evidented by an affinity-purification mass spectrometry experiment" ; rdfs:subClassOf obo:CIDO_0000058 . obo:CHEBI_36699 a rdfs:Class ; rdfs:label "corticosteroid hormone" ; rdfs:comment "Any of a class of steroid hormones that are produced in the adrenal cortex." ; rdfs:subClassOf obo:CHEBI_26764 , obo:CHEBI_50858 . obo:NCBITaxon_1788429 a rdfs:Class ; rdfs:label "Bat coronavirus RaBtCoV/3750" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:PR_Q5JSZ5 a rdfs:Class ; rdfs:label "protein PRRC2B (human)" ; rdfs:comment "A protein BAT2-like that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000004650 , obo:PR_000029067 . obo:DRON_00013476 a rdfs:Class ; rdfs:label "Sirolimus" ; rdfs:subClassOf obo:OBI_0000047 . obo:NCBITaxon_931907 a rdfs:Class ; rdfs:label "Alphacoronavirus Eptesicus fuscus/Appalachian Ridge/P1-C328/IT/USA/2009" ; rdfs:subClassOf obo:NCBITaxon_366617 . obo:PR_000004878 a rdfs:Class ; rdfs:label "complement C1q subcomponent subunit C" ; rdfs:comment "A protein that is a translation product of the human C1QC gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:CIDO_0001012 a rdfs:Class ; rdfs:label "BNT162a1 SARS-CoV-2 Vaccine" ; rdfs:subClassOf obo:CHEBI_23367 . obo:CHEBI_26373 a rdfs:Class ; rdfs:label "pteridines" ; rdfs:subClassOf obo:CHEBI_27171 , obo:CHEBI_33833 , obo:CHEBI_38101 . obo:NCBITaxon_497935 a rdfs:Class ; rdfs:label "Bat coronavirus M.das/Germany/D3.28/2007" ; rdfs:subClassOf obo:NCBITaxon_366617 . obo:CIDO_0000974 a rdfs:Class ; rdfs:label "SARS-CoV2 orf3a protein binding to human CLCC1" ; rdfs:comment "SARS-CoV2 orf3a protein binding to human CLCC1, as evidented by an affinity-purification mass spectrometry experiment" ; rdfs:subClassOf obo:CIDO_0000584 . obo:GO_0044255 a rdfs:Class ; rdfs:label "cellular lipid metabolic process" ; rdfs:comment "The chemical reactions and pathways involving lipids, as carried out by individual cells." ; rdfs:subClassOf obo:GO_0006629 , obo:GO_0044237 . obo:NCBITaxon_550976 a rdfs:Class ; rdfs:label "Bat coronavirus M.sch/Australia/CoV146/2007" ; rdfs:subClassOf obo:NCBITaxon_366617 . a rdfs:Class ; rdfs:label "RNA Replication Alteration [PE]" ; rdfs:subClassOf . obo:PR_P00748 a rdfs:Class ; rdfs:label "coagulation factor XII (human)" ; rdfs:comment "A coagulation factor XII that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000007296 , obo:PR_000029067 . obo:CHEBI_189684 a rdfs:Class ; rdfs:label "sigma-2 receptor agonist" ; rdfs:comment "A sigma receptor modulator that activates the sigma-2 receptor." ; rdfs:subClassOf obo:CHEBI_189683 . obo:CIDO_0000243 a rdfs:Class ; rdfs:label "coronaviral amino acid variant"@en ; rdfs:comment "A chemical entity that is an amino acid variant in a coronavirus proteome. Such a variant is defined by comparing with the reference strain of the coronavirus. For example, D614G is a SARS-CoV-2 coronoviral amino acid variant that has the change from D to G at the position 614 compared with the reference Wuhan strain." ; rdfs:subClassOf obo:CHEBI_24431 . obo:CHEBI_32845 a rdfs:Class ; rdfs:label "serinate" ; rdfs:comment "An alpha-amino-acid anion that is the conjugate base of serine." ; rdfs:subClassOf obo:CHEBI_33558 . obo:PR_P09917 a rdfs:Class ; rdfs:label "polyunsaturated fatty acid 5-lipoxygenase (human)" ; rdfs:comment "A polyunsaturated fatty acid 5-lipoxygenase that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000003961 , obo:PR_000029067 . obo:CIDO_0000675 a rdfs:Class ; rdfs:label "K417T in SARS-CoV-2 S protein" ; rdfs:comment "An AA mutation or AA variant that has mutated an amino acid at position 417 into a threonine in S protein." ; rdfs:subClassOf obo:CIDO_0000593 . obo:HP_0001278 a rdfs:Class ; rdfs:label "Orthostatic hypotension" ; rdfs:comment "A form of hypotension characterized by a sudden fall in blood pressure that occurs when a person assumes a standing position." ; rdfs:subClassOf obo:HP_0012332 , obo:HP_0030972 . obo:OBCS_0000095 a rdfs:Class ; rdfs:label "disease test specificity" ; rdfs:comment "A specificity that refers to the number of patients who have a negative test and do not have the disease divided by the number of patients who do not have the disease. A test with high specificity will infrequently identify patients as having a disease when they do not (i.e., few false positive results)." ; rdfs:subClassOf obo:OBCS_0000059 . obo:CIDO_0020016 a rdfs:Class ; rdfs:label "Alimetrix SARS-CoV-2 RT-PCR Assay" ; rdfs:seeAlso ; rdfs:subClassOf obo:CIDO_0000454 . obo:CHEBI_140324 a rdfs:Class ; rdfs:label "primary carboxamide" ; rdfs:comment "A carboxamide resulting from the formal condensation of a carboxylic acid with ammonia; formula RC(=O)NH2." ; rdfs:subClassOf obo:CHEBI_37622 . obo:PR_Q8NEW0 a rdfs:Class ; rdfs:label "zinc transporter 7 (human)" ; rdfs:comment "A zinc transporter 7 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000015080 , obo:PR_000029067 . obo:NCBITaxon_1532165 a rdfs:Class ; rdfs:label "Alphacoronavirus BtCoV/GrNC2/Neo_cap/RSA/2012" ; rdfs:subClassOf obo:NCBITaxon_366617 . obo:GO_1902188 a rdfs:Class ; rdfs:label "obsolete positive regulation of viral release from host cell" ; rdfs:comment "OBSOLETE. Any process that activates or increases the frequency, rate or extent of viral release from host cell." . obo:GO_0003007 a rdfs:Class ; rdfs:label "heart morphogenesis" ; rdfs:comment "The developmental process in which the heart is generated and organized. The heart is a hollow, muscular organ, which, by contracting rhythmically, keeps up the circulation of the blood." ; rdfs:subClassOf obo:GO_0032502 . obo:CHEBI_37948 a rdfs:Class ; rdfs:label "oxaspiro compound" ; rdfs:comment "A spiro compound in which at least one of the cyclic components is an oxygen heterocyle." ; rdfs:subClassOf obo:CHEBI_33599 . obo:PR_Q9BV19 a rdfs:Class ; rdfs:label "uncharacterized protein C1orf50 (human)" ; rdfs:comment "An uncharacterized protein C1orf50 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000029067 , obo:PR_000060053 . obo:OGMS_0000060 a rdfs:Class ; rdfs:label "bodily process" ; rdfs:subClassOf obo:BFO_0000015 . obo:PR_Q5T1M5 a rdfs:Class ; rdfs:label "FK506-binding protein 15 (human)" ; rdfs:comment "An FK506-binding protein 15 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000007535 , obo:PR_000029067 . obo:CHEBI_57427 a rdfs:Class ; rdfs:label "L-leucine zwitterion" ; rdfs:comment "Zwitterionic form of L-leucine." ; rdfs:subClassOf obo:CHEBI_35238 . obo:CHEBI_35337 a rdfs:Class ; rdfs:label "central nervous system stimulant" ; rdfs:comment "Any drug that enhances the activity of the central nervous system." ; rdfs:subClassOf obo:CHEBI_35470 . obo:CIDO_0000904 a rdfs:Class ; rdfs:label "SARS-CoV2 nsp7 protein binding to human MTARC1" ; rdfs:comment "SARS-CoV2 nsp7 protein binding to human MTARC1, as evidented by an affinity-purification mass spectrometry experiment" ; rdfs:subClassOf obo:CIDO_0000049 . obo:GO_0060080 a rdfs:Class ; rdfs:label "inhibitory postsynaptic potential" ; rdfs:comment "A process that causes a temporary decrease in postsynaptic membrane potential due to the flow of negatively charged ions into the postsynaptic cell. The flow of ions that causes an IPSP is an inhibitory postsynaptic current (IPSC) and makes it more difficult for the neuron to fire an action potential." ; rdfs:subClassOf obo:GO_0065008 . obo:PR_O75914 a rdfs:Class ; rdfs:label "serine/threonine-protein kinase PAK 3 (human)" ; rdfs:comment "A serine/threonine-protein kinase PAK 3 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000012242 , obo:PR_000029067 . a rdfs:Class ; rdfs:label "DIGITOXIN" ; rdfs:subClassOf . obo:CIDO_0000794 a rdfs:Class ; rdfs:label "SARS-CoV2 nsp1 protein binding to human POLA2" ; rdfs:comment "SARS-CoV2 nsp1 protein binding to human POLA2, as evidented by an affinity-purification mass spectrometry experiment" ; rdfs:subClassOf obo:CIDO_0000062 . obo:CHEBI_30751 a rdfs:Class ; rdfs:label "formic acid" ; rdfs:comment "The simplest carboxylic acid, containing a single carbon. Occurs naturally in various sources including the venom of bee and ant stings, and is a useful organic synthetic reagent. Principally used as a preservative and antibacterial agent in livestock feed. Induces severe metabolic acidosis and ocular injury in human subjects." ; rdfs:subClassOf obo:CHEBI_25384 . obo:CHEBI_24782 a rdfs:Class ; rdfs:label "imide" ; rdfs:subClassOf obo:CHEBI_33257 . obo:UBERON_0002097 a rdfs:Class ; rdfs:label "skin of body" ; rdfs:comment "The organ covering the body that consists of the dermis and epidermis." ; rdfs:subClassOf obo:UBERON_0000062 , obo:UBERON_0000465 , obo:UBERON_0004121 . obo:OPMI_0000496 a rdfs:Class ; rdfs:label "telehealth visit"@en ; rdfs:comment "A visit in which a patient engages with a Provider through communication media. A patient can use digital information and communication technologies, such as computers and mobile devices, to access health care services remotely and manage their health care." ; rdfs:subClassOf obo:OPMI_0000482 . obo:PR_O75116 a rdfs:Class ; rdfs:label "Rho-associated protein kinase 2 (human)" ; rdfs:comment "A Rho-associated protein kinase 2 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000000121 , obo:PR_000029067 . obo:PR_000012621 a rdfs:Class ; rdfs:label "progesterone receptor" ; rdfs:comment "A protein that is a translation product of the human PGR gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:PR_000013578 a rdfs:Class ; rdfs:label "Ras-related protein Rab-10" ; rdfs:comment "A protein that is a translation product of the human RAB10 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . a rdfs:Class ; rdfs:label "Vascular Diseases [Disease/Finding]" ; rdfs:subClassOf . obo:DRON_00000031 a rdfs:Class ; rdfs:label "drug administration"@en ; rdfs:comment "a treatment that has as participants an extended organism and a drug product and that results in part of the drug product being located in the extended organism"@en ; rdfs:subClassOf obo:OGMS_0000090 . obo:CHEBI_75763 a rdfs:Class ; rdfs:label "eukaryotic metabolite" ; rdfs:comment "Any metabolite produced during a metabolic reaction in eukaryotes, the taxon that include members of the fungi, plantae and animalia kingdoms." ; rdfs:subClassOf obo:CHEBI_25212 . obo:CHEBI_3095 a rdfs:Class ; rdfs:label "biguanide" ; rdfs:subClassOf obo:CHEBI_24436 . obo:NCBITaxon_389139 a rdfs:Class ; rdfs:label "Bat coronavirus (BtCoV/A620/2005)" ; rdfs:subClassOf obo:NCBITaxon_389126 . a rdfs:Class ; rdfs:label "lopinavir [Chemical/Ingredient]" ; rdfs:subClassOf . obo:PR_000009671 a rdfs:Class ; rdfs:label "La-related protein 4B" ; rdfs:comment "A protein that is a translation product of the human LARP4B gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:PR_000050287 a rdfs:Class ; rdfs:label "uridylate-specific endoribonuclease (SARS-CoV-2)" ; rdfs:comment "An ORF1ab proteolytic cleavage product (SARS-CoV-2) that is the central portion produced by the enzymatic action of 3CL-PRO proteinase (nsp5) when it cleaves the precursor replicase polyprotein 1ab (SARS-CoV-2) between residues 6452-6453 and 6798-6799. UniProtKB:P0DTD1, 6453-6798." ; rdfs:subClassOf obo:PR_000050283 . obo:CIDO_0001059 a rdfs:Class ; rdfs:label "SARS-CoV2 orf9c protein binding to human PIGO" ; rdfs:comment "SARS-CoV2 orf9c protein binding to human PIGO, as evidented by an affinity-purification mass spectrometry experiment" ; rdfs:subClassOf obo:CIDO_0000054 . obo:CHEBI_63687 a rdfs:Class ; rdfs:label "(-)-(11S,2'R)-erythro-mefloquine" ; rdfs:comment "An optically active form of [2,8-bis(trifluoromethyl)quinolin-4-yl]-(2-piperidyl)methanol having (-)-(11S,2'R)-erythro-configuration. An antimalarial agent, used in racemic form, which acts as a blood schizonticide; its mechanism of action is unknown." ; rdfs:subClassOf obo:CHEBI_63681 . a rdfs:Class ; rdfs:label "Abortion, Spontaneous [Disease/Finding]" ; rdfs:subClassOf . a rdfs:Class ; rdfs:label "Chlamydia Infections [Disease/Finding]" ; rdfs:subClassOf , . obo:NCBITaxon_1159901 a rdfs:Class ; rdfs:label "Deltacoronavirus" ; rdfs:subClassOf obo:NCBITaxon_2501931 . obo:PR_000050271 a rdfs:Class ; rdfs:label "non-structural protein 2 (SARS-CoV-2)" ; rdfs:comment "A rep gene proteolytic cleavage product (SARS-CoV-2) that is the central portion produced by the enzymatic action of PL-PRO proteinase (nsp3) when it cleaves the precursor rep gene translation product (SARS-CoV-2) between residues 180-181 and 818-819." ; rdfs:subClassOf obo:PR_000050281 . obo:GO_0051173 a rdfs:Class ; rdfs:label "positive regulation of nitrogen compound metabolic process" ; rdfs:comment "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving nitrogen or nitrogenous compounds." ; rdfs:subClassOf obo:GO_0009893 , obo:GO_0051171 . obo:CIDO_0020094 a rdfs:Class ; rdfs:label "COVID-19 IgG/IgM Rapid Test Cassette (Whole Blood/Serum/Plasma)" ; rdfs:seeAlso ; rdfs:subClassOf obo:CIDO_0000454 . obo:UBERON_0001567 a rdfs:Class ; rdfs:label "cheek" ; rdfs:comment "A fleshy subdivision of one side of the face bounded by an eye, ear and the nose." ; rdfs:subClassOf obo:UBERON_0000465 . obo:CIDO_0020120 a rdfs:Class ; rdfs:label "Dimension Vista SARS-CoV-2 Total antibody assay (COV2T)" ; rdfs:seeAlso ; rdfs:subClassOf obo:CIDO_0000454 . obo:PR_000010721 a rdfs:Class ; rdfs:label "mitochondrial ribosome-associated GTPase 1" ; rdfs:comment "A protein that is a translation product of the human MTG1 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:NCBITaxon_389151 a rdfs:Class ; rdfs:label "Bat coronavirus (BtCoV/A895/2005)" ; rdfs:subClassOf obo:NCBITaxon_389126 . obo:NCBITaxon_1429855 a rdfs:Class ; rdfs:label "Betacoronavirus Nyctalus noctula/Italy/206679-5/2010" ; rdfs:subClassOf obo:NCBITaxon_696098 . obo:CHEBI_33284 a rdfs:Class ; rdfs:label "nutrient" ; rdfs:comment "A nutrient is a food component that an organism uses to survive and grow." ; rdfs:subClassOf obo:CHEBI_78295 . obo:PR_000001177 a rdfs:Class ; rdfs:label "D(2) dopamine receptor" ; rdfs:comment "A D(2)-like dopamine receptor that is a translation product of the human DRD2 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000001108 . obo:GO_0008654 a rdfs:Class ; rdfs:label "phospholipid biosynthetic process" ; rdfs:comment "The chemical reactions and pathways resulting in the formation of a phospholipid, a lipid containing phosphoric acid as a mono- or diester." ; rdfs:subClassOf obo:GO_0006644 , obo:GO_0008610 , obo:GO_0044249 , obo:GO_0090407 . obo:CIDO_0000347 a rdfs:Class ; rdfs:label "SARS-CoV-2 Nsp15 protein interaction with host protein"@en ; rdfs:comment "A molecular interaction that has participant of the SARS-CoV-2 Nsp15 protein and a host protein" ; rdfs:subClassOf obo:CIDO_0000348 . obo:PR_000004997 a rdfs:Class ; rdfs:label "guided entry of tail-anchored proteins factor CAMLG" ; rdfs:comment "A protein that is a translation product of the human CAMLG gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:CHEBI_76835 a rdfs:Class ; rdfs:label "EC 1.1.1.* (oxidoreductase acting on donor CH-OH group, NAD(+) or NADP(+) acceptor) inhibitor" ; rdfs:comment "An EC 1.1.* (oxidoreductase acting on donor CH-OH group) inhibitor that uses NAD(+) or NADP(+) as acceptor (EC 1.1.1.*)." ; rdfs:subClassOf obo:CHEBI_76726 . obo:PR_Q15418 a rdfs:Class ; rdfs:label "ribosomal protein S6 kinase alpha-1 (human)" ; rdfs:comment "A ribosomal protein S6 kinase alpha-1 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000014282 , obo:PR_000029067 . obo:CHEBI_48407 a rdfs:Class ; rdfs:label "antiparkinson drug" ; rdfs:comment "A drug used in the treatment of Parkinson's disease." ; rdfs:subClassOf obo:CHEBI_66956 . obo:CHEBI_32760 a rdfs:Class ; rdfs:label "L-tyrosinate(1-)" ; rdfs:comment "An optically active form of tyrosinate having L-configuration." ; rdfs:subClassOf obo:CHEBI_32784 , obo:CHEBI_59814 . a rdfs:Class ; rdfs:label "Reproductive System Activity Alteration [PE]" ; rdfs:subClassOf . obo:NCBITaxon_1679907 a rdfs:Class ; rdfs:label "Coronavirus RCoV/KS10_2864/Myo_glar/GER/2010" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:CIDO_0001027 a rdfs:Class ; rdfs:label "Tin protoporphyrin IX" ; rdfs:subClassOf obo:CHEBI_23367 . a rdfs:Class ; rdfs:label "Mite Infestations [Disease/Finding]" ; rdfs:subClassOf . obo:CHEBI_32456 a rdfs:Class ; rdfs:label "cysteinate(1-)" ; rdfs:comment "A sulfur-containing amino-acid anion that is the conjugate base of cysteine, obtained by deprotonation of the carboxy group." ; rdfs:subClassOf obo:CHEBI_33558 , obo:CHEBI_63470 . obo:CIDO_0000660 a rdfs:Class ; rdfs:label "D118H in SARS-CoV-2 S protein" ; rdfs:comment "An AA mutation or AA variant that has mutated an amino acid at position 118 into a histidine in S protein." ; rdfs:subClassOf obo:CIDO_0000594 . obo:NCBITaxon_389253 a rdfs:Class ; rdfs:label "Bat coronavirus (BtCoV/A437/2005)" ; rdfs:subClassOf obo:NCBITaxon_389126 . obo:NCBITaxon_389157 a rdfs:Class ; rdfs:label "Bat coronavirus (BtCoV/908/2005)" ; rdfs:subClassOf obo:NCBITaxon_389126 . obo:CHEBI_50247 a rdfs:Class ; rdfs:label "antidote" ; rdfs:comment "Any protective agent counteracting or neutralizing the action of poisons." ; rdfs:subClassOf obo:CHEBI_50267 . a rdfs:Class ; rdfs:label "Blood Pressure Alteration [PE]" ; rdfs:subClassOf . obo:CHEBI_35488 a rdfs:Class ; rdfs:label "central nervous system depressant" ; rdfs:comment "A loosely defined group of drugs that tend to reduce the activity of the central nervous system." ; rdfs:subClassOf obo:CHEBI_35470 . obo:PR_000005943 a rdfs:Class ; rdfs:label "casein kinase I isoform alpha" ; rdfs:comment "A protein that is a translation product of the human CSNK1A1 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:PR_000001300 a rdfs:Class ; rdfs:label "CD209 molecule" ; rdfs:comment "A protein that is a translation product of the human CD209 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:CIDO_0000336 a rdfs:Class ; rdfs:label "WTFGAGAALQIPFAM"@en ; rdfs:subClassOf obo:CIDO_0000314 . obo:NCBITaxon_681849 a rdfs:Class ; rdfs:label "Kenya bat coronavirus BtKY02" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:NCBITaxon_272755 a rdfs:Class ; rdfs:label "Human coronavirus 1196/2001/NL" ; rdfs:subClassOf obo:NCBITaxon_277944 . obo:VO_0005352 a rdfs:Class ; rdfs:label "VLPCOV-01"@en ; rdfs:comment "A SARS-CoV-2 RNA vaccine manufactured by VLP Therapeutics Japan, LLC" ; rdfs:subClassOf obo:VO_0005198 . obo:IDO_0000501 a rdfs:Class ; rdfs:label "passive immunization against infectious agent"@en ; rdfs:comment "An immunization that begins with transfer to an organism of molecules not produced by that organism and that confer immunity against an infectious agent."@en ; rdfs:subClassOf obo:IDO_0000497 . obo:BFO_0000141 a rdfs:Class ; rdfs:label "immaterial entity"@en ; rdfs:subClassOf obo:BFO_0000004 . obo:NCBITaxon_931893 a rdfs:Class ; rdfs:label "Alphacoronavirus Eptesicus fuscus/Appalachian Ridge/P1-C837/IT/USA/2009" ; rdfs:subClassOf obo:NCBITaxon_366617 . obo:NCBITaxon_32525 a rdfs:Class ; rdfs:label "Theria " ; rdfs:subClassOf obo:NCBITaxon_40674 . obo:CHEBI_24995 a rdfs:Class ; rdfs:label "lactam" ; rdfs:comment "Cyclic amides of amino carboxylic acids, having a 1-azacycloalkan-2-one structure, or analogues having unsaturation or heteroatoms replacing one or more carbon atoms of the ring." ; rdfs:subClassOf obo:CHEBI_23443 , obo:CHEBI_37622 , obo:CHEBI_38101 . obo:GO_0034061 a rdfs:Class ; rdfs:label "DNA polymerase activity" ; rdfs:comment "Catalysis of the reaction: deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1); the synthesis of DNA from deoxyribonucleotide triphosphates in the presence of a nucleic acid template and a 3'hydroxyl group." ; rdfs:subClassOf obo:GO_0003824 . obo:GO_0042327 a rdfs:Class ; rdfs:label "positive regulation of phosphorylation" ; rdfs:comment "Any process that activates or increases the frequency, rate or extent of addition of phosphate groups to a molecule." ; rdfs:subClassOf obo:GO_0042325 , obo:GO_0045937 . obo:PR_Q13438 a rdfs:Class ; rdfs:label "protein OS-9 (human)" ; rdfs:comment "A protein OS-9 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000012042 , obo:PR_000029067 . obo:CHEBI_55323 a rdfs:Class ; rdfs:label "antidiarrhoeal drug" ; rdfs:comment "Any drug found useful in the symptomatic treatment of diarrhoea." ; rdfs:subClassOf obo:CHEBI_55324 . obo:PR_000001322 a rdfs:Class ; rdfs:label "angiotensin-converting enzyme" ; rdfs:comment "A protein that is a translation product of the human ACE gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:UBERON_0001088 a rdfs:Class ; rdfs:label "urine" ; rdfs:comment "Excretion that is the output of a kidney" ; rdfs:subClassOf obo:UBERON_0000463 . obo:NCBITaxon_1076415 a rdfs:Class ; rdfs:label "Alphacoronavirus M.sch/A/Spain/2004" ; rdfs:subClassOf obo:NCBITaxon_366617 . obo:CIDO_0000512 a rdfs:Class ; rdfs:label "CVEMHNKINLCDDPE" ; rdfs:comment "A coronavirus epitope that is part of some S protein from HCoV 229E composed of the following amino acids CVEMHNKINLCDDPE" ; rdfs:subClassOf obo:CIDO_0000451 . obo:CIDO_0020019 a rdfs:Class ; rdfs:label "Allplex 2019-nCoV Assay" ; rdfs:seeAlso ; rdfs:subClassOf obo:CIDO_0000454 . obo:GO_0002034 a rdfs:Class ; rdfs:label "maintenance of blood vessel diameter homeostasis by renin-angiotensin" ; rdfs:comment "The process in which the diameter of a blood vessel is changed due to activity of the renin-angiotensin system." ; rdfs:subClassOf obo:GO_0003008 , obo:GO_0003081 , obo:GO_0097746 . obo:CIDO_0020191 a rdfs:Class ; rdfs:label "LumiraDx SARS-CoV-2 Ag Test" ; rdfs:seeAlso ; rdfs:subClassOf obo:CIDO_0000454 . a rdfs:Class ; rdfs:label "Proscillaridin [Chemical/Ingredient]" ; rdfs:subClassOf . obo:CIDO_0020083 a rdfs:Class ; rdfs:label """cobas SARS-CoV-2 & Influenza A/B Nucleic Acid Test for use on the cobas Liat System""" ; rdfs:seeAlso ; rdfs:subClassOf obo:CIDO_0000454 . obo:CHEBI_29922 a rdfs:Class ; rdfs:label "sulfo group" ; rdfs:subClassOf obo:CHEBI_33246 . obo:APOLLO_SV_00000286 a rdfs:Class ; rdfs:label "close individual places independently strategy"@en ; rdfs:comment "A place-closure control strategy that decides on a case-by-case basis whether to close places of a certain type, as opposed to blanket policy that closes all places of a certain type at the same time."@en ; rdfs:subClassOf obo:APOLLO_SV_00000229 . obo:CIDO_0000542 a rdfs:Class ; rdfs:label "SALEDLLFSKVVTSG" ; rdfs:comment "A coronavirus epitope that is part of some S protein from HCoV NL63 composed of the following amino acids SALEDLLFSKVVTSG" ; rdfs:subClassOf obo:CIDO_0000449 . obo:VO_0005131 a rdfs:Class ; rdfs:label "VRP-SARS-N vaccine" ; rdfs:comment "A SARS recombinant vector vaccine made from Venezuelan equine encephalitis replicons (VRP) encoding a SARS-CoV CD4+ T cell epitope vaccinated intranasally. Crosslisted as MERS vaccine (VIOLINID:5789). Efficacy higher intranasally than subcutaneously." ; rdfs:subClassOf obo:VO_0012183 . obo:PR_Q96K12 a rdfs:Class ; rdfs:label "fatty acyl-CoA reductase 2 (human)" ; rdfs:comment "A fatty acyl-CoA reductase 2 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000007342 , obo:PR_000029067 . obo:NCBITaxon_237639 a rdfs:Class ; rdfs:label "SARS coronavirus Taiwan TC1" ; rdfs:subClassOf obo:NCBITaxon_694009 . obo:PR_P06149 a rdfs:Class ; rdfs:label "quinone-dependent D-lactate dehydrogenase (Escherichia coli K-12)" ; rdfs:comment "A quinone-dependent D-lactate dehydrogenase that is encoded in the genome of Escherichia coli K-12." ; rdfs:subClassOf obo:PR_000029062 , obo:PR_000034089 . obo:PR_000008922 a rdfs:Class ; rdfs:label "interferon-alpha/beta receptor alpha chain" ; rdfs:comment "A protein that is a translation product of the human IFNAR1 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:CIDO_0020300 a rdfs:Class ; rdfs:label "STANDARD M nCoV Real-Time Detection Kit" ; rdfs:seeAlso ; rdfs:subClassOf obo:CIDO_0000454 . obo:APOLLO_SV_00000512 a rdfs:Class ; rdfs:label "rate of hydrological precipitation"@en ; rdfs:comment "A rate measurement datum that is the result of the measurement of the volume of water produced by some hydrological precipitation process at a particular geographical region divided by the number of temporal intervals of equal duration over which the precipitation occurred."@en ; rdfs:subClassOf obo:OBI_0001554 . obo:CHEBI_33692 a rdfs:Class ; rdfs:label "hydrides" ; rdfs:comment "Hydrides are chemical compounds of hydrogen with other chemical elements." ; rdfs:subClassOf obo:CHEBI_33608 , obo:CHEBI_37577 . obo:PR_000001128 a rdfs:Class ; rdfs:label "chemokine receptor" ; rdfs:comment "A rhodopsin-like G-protein coupled receptor that in active form binds to one or more chemokines." ; rdfs:subClassOf obo:PR_000001094 . obo:CIDO_0000987 a rdfs:Class ; rdfs:label "SARS-CoV2 orf8 protein binding to human ADAMTS1" ; rdfs:comment "SARS-CoV2 orf8 protein binding to human ADAMTS1, as evidented by an affinity-purification mass spectrometry experiment" ; rdfs:subClassOf obo:CIDO_0000051 . obo:CHEBI_52898 a rdfs:Class ; rdfs:label "azamacrocycle" ; rdfs:comment "A cyclic macromolecule containing one or more nitrogen atoms in place of carbon either as the divalent group NH for the group CH2 or a single trivalent nitrogen atom for the group CH." ; rdfs:subClassOf obo:CHEBI_51026 . obo:NCBITaxon_349342 a rdfs:Class ; rdfs:label "Bat SARS coronavirus Rp1" ; rdfs:subClassOf obo:NCBITaxon_694009 . obo:GO_2000379 a rdfs:Class ; rdfs:label "positive regulation of reactive oxygen species metabolic process" ; rdfs:comment "Any process that activates or increases the frequency, rate or extent of reactive oxygen species metabolic process." ; rdfs:subClassOf obo:GO_0031323 , obo:GO_0031325 . obo:CHEBI_50326 a rdfs:Class ; rdfs:label "sulfanylmethyl group" ; rdfs:subClassOf obo:CHEBI_50325 . obo:PR_Q4G0J3 a rdfs:Class ; rdfs:label "La-related protein 7 (human)" ; rdfs:comment "A La-related protein 7 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000009673 , obo:PR_000029067 . obo:PR_P10614 a rdfs:Class ; rdfs:label "lanosterol 14-alpha demethylase CYP51 (yeast)" ; rdfs:comment "A lanosterol 14-alpha demethylase that is encoded in the genome of yeast." ; rdfs:subClassOf obo:PR_000006147 , obo:PR_000029055 . obo:NCBITaxon_903578 a rdfs:Class ; rdfs:label "Kenya bat coronavirus BtKY110" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:CHEBI_33238 a rdfs:Class ; rdfs:label "monoatomic entity" ; rdfs:comment "A monoatomic entity is a molecular entity consisting of a single atom." ; rdfs:subClassOf obo:CHEBI_33259 . obo:GO_0065003 a rdfs:Class ; rdfs:label "protein-containing complex assembly" ; rdfs:comment "The aggregation, arrangement and bonding together of a set of macromolecules to form a protein-containing complex." ; rdfs:subClassOf obo:GO_0016043 , obo:GO_0043933 . obo:NCBITaxon_1559519 a rdfs:Class ; rdfs:label "Porcine deltacoronavirus KNU14-04" ; rdfs:subClassOf obo:NCBITaxon_1159905 . obo:CIDO_0000490 a rdfs:Class ; rdfs:label "DTCFGVSKPNAIDVE" ; rdfs:comment "A coronavirus epitope that is part of some S protein from HCoV NL63 composed of the following amino acids DTCFGVSKPNAIDVE" ; rdfs:subClassOf obo:CIDO_0000449 . obo:NCBITaxon_663565 a rdfs:Class ; rdfs:label "Bat SARS Cov Rs806/2006" ; rdfs:subClassOf obo:NCBITaxon_696098 . obo:PR_000011520 a rdfs:Class ; rdfs:label "nucleoporin p54" ; rdfs:comment "A protein that is a translation product of the human NUP54 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . a rdfs:Class ; rdfs:label "Amino Acids, Peptides, and Proteins [Chemical/Ingredient]" ; rdfs:subClassOf . obo:CIDO_0000743 a rdfs:Class ; rdfs:label "S13I in SARS-CoV-2 S protein"@en ; rdfs:comment "An AA variant that has mutated an amino acid at position 13 into isoleucine in S protein" ; rdfs:subClassOf obo:CIDO_0000594 . obo:PR_Q8IWF2 a rdfs:Class ; rdfs:label "FAD-dependent oxidoreductase domain-containing protein 2 (human)" ; rdfs:comment "An FAD-dependent oxidoreductase domain-containing protein 2 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000029067 , obo:PR_000030713 . a rdfs:Class ; rdfs:label "Encephalitis, Arbovirus [Disease/Finding]" ; rdfs:subClassOf , , . obo:CHEBI_59772 a rdfs:Class ; rdfs:label "hemiketal" ; rdfs:comment "A hemiacetal having the structure RR(1)C(OH)OR(2) (R, R(1), R(2) =/= H), derived from a ketone by formal addition of an alcohol to the carbonyl group." ; rdfs:subClassOf obo:CHEBI_5653 . obo:HP_0031245 a rdfs:Class ; rdfs:label "Productive cough" ; rdfs:comment "A cough that produces phlegm or mucus." ; rdfs:subClassOf obo:HP_0012735 . obo:NCBITaxon_2509496 a rdfs:Class ; rdfs:label "Minacovirus" ; rdfs:subClassOf obo:NCBITaxon_693996 . obo:NCBITaxon_1897081 a rdfs:Class ; rdfs:label "Bat coronavirus Stu.lil/1617/BRA/2012" ; rdfs:subClassOf obo:NCBITaxon_366617 . obo:CIDO_0001139 a rdfs:Class ; rdfs:label "SARS-CoV-2 BA.2 virus"@en ; rdfs:comment "A SARS-CoV-2 Omicron variant virus that has a majority of the following mutations:" ; rdfs:subClassOf obo:CIDO_0000406 , obo:CIDO_0000590 . obo:CHEBI_47780 a rdfs:Class ; rdfs:label "clomipramine" ; rdfs:comment "A dibenzoazepine that is 10,11-dihydro-5H-dibenzo[b,f]azepine which is substituted by chlorine at position 3 and in which the hydrogen attached to the nitrogen is replaced by a 3-(dimethylamino)propyl group. One of the more sedating tricyclic antidepressants, it is used as the hydrochloride salt for the treatment of depression as well as obsessive-compulsive disorder and phobias." ; rdfs:subClassOf obo:CHEBI_36809 , obo:CHEBI_47804 . obo:CHEBI_57726 a rdfs:Class ; rdfs:label "D-proline zwitterion" ; rdfs:comment "A D-alpha-amino acid zwitterion that is D-proline in which a proton has been transferred from the carboxy group to the amino group. It is the major species at pH 7.3." ; rdfs:subClassOf obo:CHEBI_59871 . obo:CHEBI_36094 a rdfs:Class ; rdfs:label "organic chloride salt" ; rdfs:subClassOf obo:CHEBI_23114 , obo:CHEBI_51069 . obo:NCBITaxon_30560 a rdfs:Class ; rdfs:label "Microchiroptera" ; rdfs:subClassOf obo:NCBITaxon_9397 . obo:NCBITaxon_1269292 a rdfs:Class ; rdfs:label "Coronavirus BCoV/PB675/Art_lit/PAN/2011" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:NCBITaxon_1269300 a rdfs:Class ; rdfs:label "Coronavirus BtCoV/KCR216/Car_per/CRC/2010" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:HP_0001692 a rdfs:Class ; rdfs:label "Atrial arrhythmia" ; rdfs:comment "A type of supraventricular tachycardia in which the atria are the principal site of electrophysiologic disturbance." ; rdfs:subClassOf obo:HP_0005115 . obo:APOLLO_SV_00000548 a rdfs:Class ; rdfs:label "Susceptible-Infected-Susceptible model"@en ; rdfs:comment "A compartmental disease transmission model that represents some infection in ecosystem in which there is only a susceptible population and an infectious population, such that individuals who aren't infectious are susceptible."@en ; rdfs:subClassOf obo:APOLLO_SV_00000303 . obo:CHEBI_67197 a rdfs:Class ; rdfs:label "endocannabinoid" ; rdfs:comment "A class of cannabinoids present in mammalian biological fluids and tissues that activate cannabinoid receptors." ; rdfs:subClassOf obo:CHEBI_18059 , obo:CHEBI_67194 . obo:CHEBI_25359 a rdfs:Class ; rdfs:label "modified amino acid" ; rdfs:subClassOf obo:CHEBI_33709 . obo:CIDO_0000399 a rdfs:Class ; rdfs:label "SARS-CoV-2 B.1.617.2 virus"@en ; rdfs:comment "A SARS-CoV-2 Delta variant virus that has a majority of the following amino acid mutations: S:T19R ,S:L452R , S:T478K .S:P681R ,S:D950N, ORF3a:S26L, M:I82T, ORF7a:V82A , ORF7a:T120I, N:D63G, N:R203M, N:D377Y" ; rdfs:subClassOf obo:CIDO_0000376 , obo:CIDO_0000406 . obo:CIDO_0000610 a rdf:Property ; rdfs:label "has average R0"@en ; rdfs:comment "A data property that represents a relation between an infectious agent (such as a viral strain) and a value that is the averge number of transmissions, i.e., the basic reproduction number (or called R0 value)." ; rdfs:seeAlso obo:CIDO_0000589 ; rdfs:range . obo:NCBITaxon_285267 a rdfs:Class ; rdfs:label "SARS coronavirus HHS-2004" ; rdfs:subClassOf obo:NCBITaxon_694009 . obo:UBERON_0000955 a rdfs:Class ; rdfs:label "brain" ; rdfs:comment "The brain is the center of the nervous system in all vertebrate, and most invertebrate, animals. Some primitive animals such as jellyfish and starfish have a decentralized nervous system without a brain, while sponges lack any nervous system at all. In vertebrates, the brain is located in the head, protected by the skull and close to the primary sensory apparatus of vision, hearing, balance, taste, and smell[WP]." ; rdfs:subClassOf obo:UBERON_0000465 . obo:OPMI_0000560 a rdfs:Class ; rdfs:label "resolved condition status"@en ; rdfs:comment "A medical condition status in which the subject is not presently experiencing the condition or situation and there is a negligible perceived risk of the condition or situation returning." ; rdfs:subClassOf obo:OPMI_0000533 . obo:PR_000016378 a rdfs:Class ; rdfs:label "serine/threonine-protein kinase tousled-like 2" ; rdfs:comment "A protein that is a translation product of the human TLK2 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:NCBITaxon_903580 a rdfs:Class ; rdfs:label "Kenya bat coronavirus BtKY112" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:CHEBI_189675 a rdfs:Class ; rdfs:label "PAR2 negative allosteric modulator" ; rdfs:comment "a group of substances that bind to a receptor to change that receptor's response to stimulus." ; rdfs:subClassOf obo:CHEBI_189676 , obo:CHEBI_90710 . obo:CIDO_0000351 a rdfs:Class ; rdfs:label "COVID-19 chemiluminescent diagnostic assay"@en ; rdfs:comment "A COVID-19 serological diagnostic assay that tests the serum from the blood specimen to detect the antigen-antibody complex using light emission, which is generated from a chemical reaction."@en ; rdfs:subClassOf obo:CIDO_0000262 . obo:OAE_0000394 a rdfs:Class ; rdfs:label "chills AE" ; rdfs:comment "a sensory capability AE that has an outcome of chills" ; rdfs:subClassOf obo:OAE_0000582 . obo:CIDO_0000471 a rdfs:Class ; rdfs:label "ISSTVRLQAGTATEY" ; rdfs:comment "A coronavirus epitope that is part of some S protein from HCoV OC43 composed of the following amino acids ISSTVRLQAGTATEY" ; rdfs:subClassOf obo:CIDO_0000452 . obo:OGG_3000003458 a rdfs:Class ; rdfs:label "IFNG" ; rdfs:comment "Other designations: IFN-gamma|immune interferon|interferon gamma" ; rdfs:subClassOf obo:OGG_2060009606 . obo:CL_0000738 a rdfs:Class ; rdfs:label "leukocyte" ; rdfs:comment "An achromatic cell of the myeloid or lymphoid lineages capable of ameboid movement, found in blood or other tissue." ; rdfs:subClassOf obo:CL_0000000 . obo:CIDO_0000737 a rdfs:Class ; rdfs:label "G75V in SARS-CoV-2 S protein"@en ; rdfs:comment "An AA variant that has mutated an amino acid at position 75 into valine in S protein." ; rdfs:subClassOf obo:CIDO_0000594 . obo:PR_O43818 a rdfs:Class ; rdfs:label "U3 small nucleolar RNA-interacting protein 2 (human)" ; rdfs:comment "A U3 small nucleolar RNA-interacting protein 2 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000014314 , obo:PR_000029067 . obo:PR_P01579 a rdfs:Class ; rdfs:label "interferon gamma (human)" ; rdfs:comment "An interferon gamma that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000000017 , obo:PR_000029067 . obo:GO_0016049 a rdfs:Class ; rdfs:label "cell growth" ; rdfs:comment "The process in which a cell irreversibly increases in size over time by accretion and biosynthetic production of matter similar to that already present." ; rdfs:subClassOf obo:GO_0008150 , obo:GO_0009987 . obo:HP_0030956 a rdfs:Class ; rdfs:label "Abnormality of cardiovascular system electrophysiology" ; rdfs:comment "An anomaly of the electrical conduction physiology of the heart." ; rdfs:subClassOf obo:HP_0011025 . obo:CIDO_0000246 a rdfs:Class ; rdfs:label "coronavirus entry in endosome"@en ; rdfs:subClassOf obo:CIDO_0000085 . obo:VariO_0001 a rdfs:Class ; rdfs:label "variation" ; rdfs:comment "Alteration in DNA, RNA or protein." ; rdfs:subClassOf obo:GO_0008150 . obo:NCBITaxon_264383 a rdfs:Class ; rdfs:label "SARS coronavirus TW-YM1" ; rdfs:subClassOf obo:NCBITaxon_264370 . a rdfs:Class ; rdfs:label "Physiochemical Activity [MoA]" ; rdfs:subClassOf . obo:CHEBI_22723 a rdfs:Class ; rdfs:label "benzoic acids" ; rdfs:comment "Any aromatic carboxylic acid that consists of benzene in which at least a single hydrogen has been substituted by a carboxy group." ; rdfs:subClassOf obo:CHEBI_22712 , obo:CHEBI_33859 . obo:HP_0002758 a rdfs:Class ; rdfs:label "Osteoarthritis" ; rdfs:comment "Degeneration (wear and tear) of articular cartilage, i.e., of the joint surface. Joint degeneration may be accompanied by osteophytes (bone overgrowth), narrowing of the joint space, regions of sclerosis at the joint surface, or joint deformity." ; rdfs:subClassOf obo:HP_0001369 . obo:NCBITaxon_322593 a rdfs:Class ; rdfs:label "Canine coronavirus isolate NJ17" ; rdfs:subClassOf obo:NCBITaxon_11153 . obo:NCBITaxon_258972 a rdfs:Class ; rdfs:label "SARS coronavirus TW9" ; rdfs:subClassOf obo:NCBITaxon_694009 . obo:CHEBI_32867 a rdfs:Class ; rdfs:label "D-prolinate" ; rdfs:comment "An optically active form of prolinate having D-configuration." ; rdfs:subClassOf obo:CHEBI_32871 . obo:OPMI_0000553 a rdfs:Class ; rdfs:label "immediate cause of death status"@en ; rdfs:comment "An immediate cause of death is a final disease, injury, or complication directly causing the death" ; rdfs:subClassOf obo:OPMI_0000543 . obo:CHEBI_33666 a rdfs:Class ; rdfs:label "polycyclic hydrocarbon" ; rdfs:subClassOf obo:CHEBI_33663 , obo:CHEBI_35294 . obo:PR_000012912 a rdfs:Class ; rdfs:label "mitochondrial-processing peptidase subunit beta" ; rdfs:comment "A protein that is a translation product of the human PMPCB gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:NCBITaxon_28295 a rdfs:Class ; rdfs:label "Porcine epidemic diarrhea virus" ; rdfs:subClassOf obo:NCBITaxon_2509505 . obo:NCBITaxon_11148 a rdfs:Class ; rdfs:label "Porcine respiratory coronavirus (STRAIN RM4)" ; rdfs:subClassOf obo:NCBITaxon_11146 . obo:CIDO_0001164 a rdfs:Class ; rdfs:label "AA variant in SARS-CoV-2 S protein S2 HR2 region"@en ; rdfs:subClassOf obo:CIDO_0000595 . obo:PR_000009064 a rdfs:Class ; rdfs:label "insulin receptor" ; rdfs:comment "A protein that is a translation product of the human INSR gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:HP_0005110 a rdfs:Class ; rdfs:label "Atrial fibrillation" ; rdfs:comment "An atrial arrhythmia characterized by disorganized atrial activity without discrete P waves on the surface EKG, but instead by an undulating baseline or more sharply circumscribed atrial deflections of varying amplitude an frequency ranging from 350 to 600 per minute." ; rdfs:subClassOf obo:HP_0001692 . obo:DOID_603 a rdfs:Class ; rdfs:label "AIDS phobia" ; rdfs:subClassOf obo:DOID_0060048 . obo:PR_P42681 a rdfs:Class ; rdfs:label "tyrosine-protein kinase TXK (human)" ; rdfs:comment "A tyrosine-protein kinase TXK that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000016850 , obo:PR_000029067 . obo:DRON_00831727 a rdfs:Class ; rdfs:label "baricitinib" ; rdfs:subClassOf obo:OBI_0000047 . obo:CHEBI_167559 a rdfs:Class ; rdfs:label "glycan" ; rdfs:comment "Any oligosaccharide, polysaccharide or their derivatives consisting of monosaccharides or monosaccharide derivatives linked by glycosidic bonds. See also http://www.ontobee.org/ontology/GNO?iri=http://purl.obolibrary.org/obo/GNO_00000001." ; rdfs:subClassOf obo:CHEBI_78616 . a rdfs:Class ; rdfs:label "Uterine Smooth Muscle Contraction or Tone [PE]" ; rdfs:subClassOf , . obo:CHEBI_35552 a rdfs:Class ; rdfs:label "heterocyclic organic fundamental parent" ; rdfs:subClassOf obo:CHEBI_33245 . a rdfs:Class ; rdfs:label "Fluspirilene [Chemical/Ingredient]" ; rdfs:subClassOf , , . obo:CHEBI_38313 a rdfs:Class ; rdfs:label "diazines" ; rdfs:comment "Any organic heterocyclic compound containing a benzene ring in which two of the C-H fragments have been replaced by isolobal nitrogens (the diazine parent structure)." ; rdfs:subClassOf obo:CHEBI_25693 , obo:CHEBI_38101 . obo:NCBITaxon_1699320 a rdfs:Class ; rdfs:label "Myotis Bat Alphacoronavirus strain MJ_51C" ; rdfs:subClassOf obo:NCBITaxon_366617 . obo:NCBITaxon_2042581 a rdfs:Class ; rdfs:label "Coronavirus PREDICT CoV-57" ; rdfs:subClassOf obo:NCBITaxon_696098 . obo:CHEBI_19255 a rdfs:Class ; rdfs:label "pyrimidine 2'-deoxyribonucleoside" ; rdfs:subClassOf obo:CHEBI_18274 , obo:CHEBI_26440 , obo:CHEBI_68472 . obo:DOID_605 a rdfs:Class ; rdfs:label "flying phobia" ; rdfs:comment "A specific phobia that is characterized by a fear of flying." ; rdfs:subClassOf obo:DOID_599 . obo:CHEBI_35942 a rdfs:Class ; rdfs:label "neurotransmitter agent" ; rdfs:comment "A substance used for its pharmacological action on any aspect of neurotransmitter systems. Neurotransmitter agents include agonists, antagonists, degradation inhibitors, uptake inhibitors, depleters, precursors, and modulators of receptor function." ; rdfs:subClassOf obo:CHEBI_23888 , obo:CHEBI_52210 . obo:OPMI_0000474 a rdfs:Class ; rdfs:label "month of birth"@en ; rdfs:comment "A month when an organism (e.g., a human) is born." ; rdfs:subClassOf obo:BFO_0000038 , obo:OPMI_0000478 . obo:HP_0011025 a rdfs:Class ; rdfs:label "Abnormal cardiovascular system physiology" ; rdfs:comment "Abnormal functionality of the cardiovascular system." ; rdfs:subClassOf obo:HP_0001626 . obo:NCBITaxon_1146863 a rdfs:Class ; rdfs:label "Bat coronavirus M.nattereri/UK/Wyt/1020A" ; rdfs:subClassOf obo:NCBITaxon_366617 . obo:GO_0090407 a rdfs:Class ; rdfs:label "organophosphate biosynthetic process" ; rdfs:comment "The chemical reactions and pathways resulting in the biosynthesis of deoxyribose phosphate, the phosphorylated sugar 2-deoxy-erythro-pentose." ; rdfs:subClassOf obo:GO_0019637 , obo:GO_1901576 . obo:OAE_0000226 a rdfs:Class ; rdfs:label "medical intervention site AE"@en ; rdfs:comment "an adverse event that occurs in the site of a medical intervention (e.g., vaccination injection site)." ; rdfs:subClassOf obo:OAE_0000001 . obo:DOID_11394 a rdfs:Class ; rdfs:label "adult respiratory distress syndrome" ; rdfs:comment "A respiratory failure that results from diffuse injury to the endothelium of the lung (as in sepsis, chest trauma, massive blood transfusion, aspiration of the gastric contents, or pneumonia) and is characterized by pulmonary edema with an abnormally high amount of protein in the edematous fluid and by difficult rapid breathing and hypoxemia." ; rdfs:subClassOf obo:DOID_11162 . obo:CIDO_0000803 a rdfs:Class ; rdfs:label "SARS-CoV2 nsp12 protein binding to human AKAP8" ; rdfs:comment "SARS-CoV2 nsp12 protein binding to human AKAP8, as evidented by an affinity-purification mass spectrometry experiment" ; rdfs:subClassOf obo:CIDO_0000057 . obo:CIDO_0000590 a rdfs:Class ; rdfs:label "SARS-CoV-2 Omicron variant"@en ; rdfs:subClassOf obo:CIDO_0000407 . obo:CHEBI_50860 a rdfs:Class ; rdfs:label "organic molecular entity" ; rdfs:comment "Any molecular entity that contains carbon." ; rdfs:subClassOf obo:CHEBI_33582 . obo:CIDO_0000258 a rdfs:Class ; rdfs:label "COVID-19 diagnostic assay"@en ; rdfs:comment "An assay that is used for COVID-19 diagnosis" ; rdfs:subClassOf obo:OBI_0000070 . obo:CIDO_0020265 a rdfs:Class ; rdfs:label "RightSign COVID-19 IgG/IgM Rapid Test Cassette" ; rdfs:seeAlso ; rdfs:subClassOf obo:CIDO_0000454 . obo:NCBITaxon_756642 a rdfs:Class ; rdfs:label "Bovine coronavirus cow/WDBR-841/BRA/2003" ; rdfs:subClassOf obo:NCBITaxon_11128 . obo:CHEBI_47857 a rdfs:Class ; rdfs:label "ureas" ; rdfs:subClassOf obo:CHEBI_33256 . a rdfs:Class ; rdfs:label "Cardiomyopathy, Hypertrophic [Disease/Finding]" ; rdfs:subClassOf , . obo:CIDO_0000171 a rdfs:Class ; rdfs:label "COVID-19 clinical trial drug"@en ; rdfs:subClassOf obo:CIDO_0000169 . obo:CIDO_0020318 a rdfs:Class ; rdfs:label "U-TOP COVID-19 Detection Kit" ; rdfs:seeAlso ; rdfs:subClassOf obo:CIDO_0000454 . obo:NCBITaxon_1679904 a rdfs:Class ; rdfs:label "Coronavirus RCoV/KS10_2636/Mic_arv/GER/2010" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:HP_0004758 a rdfs:Class ; rdfs:label "Effort-induced polymorphic ventricular tachycardia" ; rdfs:comment "Polymorphic ventricular arrhythmias of varying morphologythat do not exist under resting conditions but appear only upon physical exercise or catecholamine administration." ; rdfs:subClassOf obo:HP_0004756 . obo:CHEBI_189678 a rdfs:Class ; rdfs:label "modulator" ; rdfs:comment "a group of substances that bind to a receptor to change that receptor's response to stimulus" ; rdfs:subClassOf obo:CHEBI_50860 . obo:NCBITaxon_1788496 a rdfs:Class ; rdfs:label "Rhinolophus bat coronavirus BtCoV/4307-2" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:CIDO_0020298 a rdfs:Class ; rdfs:label "Sofia 2 SARS Antigen FIA" ; rdfs:seeAlso ; rdfs:subClassOf obo:CIDO_0000454 . obo:PR_Q96GD4 a rdfs:Class ; rdfs:label "aurora kinase B (human)" ; rdfs:comment "An aurora kinase B that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000004517 , obo:PR_000029067 . obo:NCBITaxon_2501931 a rdfs:Class ; rdfs:label "Orthocoronavirinae" ; rdfs:subClassOf obo:NCBITaxon_11118 . obo:CHEBI_33452 a rdfs:Class ; rdfs:label "benzylic group" ; rdfs:comment "Arylmethyl groups and derivatives formed by substitution: ArCR2-." ; rdfs:subClassOf obo:CHEBI_33249 . obo:PR_Q8IVH8 a rdfs:Class ; rdfs:label "mitogen-activated protein kinase kinase kinase kinase 3 (human)" ; rdfs:comment "A mitogen-activated protein kinase kinase kinase kinase 3 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000010145 , obo:PR_000029067 . obo:NCBITaxon_1699350 a rdfs:Class ; rdfs:label "Rousettus Bat Alphacoronavirus strain ML_32I" ; rdfs:subClassOf obo:NCBITaxon_696098 . a rdfs:Class ; rdfs:label "Enzyme Interactions [MoA]" ; rdfs:subClassOf . obo:PR_000016541 a rdfs:Class ; rdfs:label "mitochondrial import receptor subunit TOM70" ; rdfs:comment "A protein that is a translation product of the human TOMM70 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:PR_Q15303 a rdfs:Class ; rdfs:label "receptor tyrosine-protein kinase erbB-4 (human)" ; rdfs:comment "A receptor tyrosine-protein kinase erbB-4 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000007160 , obo:PR_000029067 . obo:NCBITaxon_2157 a rdfs:Class ; rdfs:label "Archaea" ; rdfs:subClassOf obo:OBI_0100026 . a rdfs:Class ; rdfs:label "Enterobacteriaceae Infections [Disease/Finding]" ; rdfs:subClassOf . obo:CHEBI_73214 a rdfs:Class ; rdfs:label "EC 3.6.3.14 (H(+)-transporting two-sector ATPase) inhibitor" ; rdfs:comment "An EC 3.6.3.* (acid anhydride hydrolase catalysing transmembrane movement of substances) inhibitor that interferes with the action of H(+)-transporting two-sector ATPase inhibitor (EC 3.6.3.14)." ; rdfs:subClassOf obo:CHEBI_76895 . obo:GO_0009607 a rdfs:Class ; rdfs:label "response to biotic stimulus" ; rdfs:comment "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a biotic stimulus, a stimulus caused or produced by a living organism." ; rdfs:subClassOf obo:GO_0050896 . obo:NCBITaxon_2042556 a rdfs:Class ; rdfs:label "Coronavirus PREDICT CoV-30" ; rdfs:subClassOf obo:NCBITaxon_696098 . a rdfs:Class ; rdfs:label "Myocardial Ischemia [Disease/Finding]" ; rdfs:subClassOf , . obo:PR_Q9P286 a rdfs:Class ; rdfs:label "serine/threonine-protein kinase PAK 5 (human)" ; rdfs:comment "A serine/threonine-protein kinase PAK 5 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000012245 , obo:PR_000029067 . obo:GO_0009966 a rdfs:Class ; rdfs:label "regulation of signal transduction" ; rdfs:comment "Any process that modulates the frequency, rate or extent of signal transduction." ; rdfs:subClassOf obo:GO_0010646 , obo:GO_0023051 , obo:GO_0048583 . obo:OAE_0001045 a rdfs:Class ; rdfs:label "hyperhidrosis AE" ; rdfs:comment "a skin AE that results in excess perspiration" ; rdfs:subClassOf obo:OAE_0000401 . obo:CHEBI_26079 a rdfs:Class ; rdfs:label "phosphoric acid derivative" ; rdfs:subClassOf obo:CHEBI_36359 . a rdfs:Class ; rdfs:label "Hexachlorophene [Chemical/Ingredient]" ; rdfs:subClassOf . a rdfs:Class ; rdfs:label "Fluphenazine Hydrochloride [Chemical/Ingredient]" ; rdfs:subClassOf . obo:CIDO_0001001 a rdfs:Class ; rdfs:label "Human interferon beta" ; rdfs:subClassOf obo:CHEBI_23367 . obo:CHEBI_37533 a rdfs:Class ; rdfs:label "azo compound" ; rdfs:comment "Derivatives of diazene with the general structure R-N=N-R'." ; rdfs:subClassOf obo:CHEBI_51143 . obo:CHEBI_37934 a rdfs:Class ; rdfs:label "1H-phenothiazine" ; rdfs:subClassOf obo:CHEBI_37932 . obo:CHEBI_35315 a rdfs:Class ; rdfs:label "deoxy hexoside" ; rdfs:subClassOf obo:CHEBI_24400 . obo:PR_Q7L2J0 a rdfs:Class ; rdfs:label "7SK snRNA methylphosphate capping enzyme (human)" ; rdfs:comment "A 7SK snRNA methylphosphate capping enzyme that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000010326 , obo:PR_000029067 . obo:PR_Q8N183 a rdfs:Class ; rdfs:label "NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 2 (human)" ; rdfs:comment "An NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 2 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000011082 , obo:PR_000029067 . obo:NCBITaxon_1964810 a rdfs:Class ; rdfs:label "Coronavirus JC66" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:CIDO_0000933 a rdfs:Class ; rdfs:label "SARS-CoV2 nsp8 protein binding to human MEPCE" ; rdfs:comment "SARS-CoV2 nsp8 protein binding to human MEPCE, as evidented by an affinity-purification mass spectrometry experiment" ; rdfs:subClassOf obo:CIDO_0000582 . obo:CIDO_0000179 a rdfs:Class ; rdfs:label "coronaviral pp1ab cleavage"@en ; rdfs:subClassOf obo:CIDO_0000204 . obo:PR_000008272 a rdfs:Class ; rdfs:label "GrpE protein homolog 1, mitochondrial" ; rdfs:comment "A protein that is a translation product of the human GRPEL1 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:NCBITaxon_299335 a rdfs:Class ; rdfs:label "SARS coronavirus B039" ; rdfs:subClassOf obo:NCBITaxon_694009 . obo:NCBITaxon_1934039 a rdfs:Class ; rdfs:label "Calidris fuscicollis coronavirus" ; rdfs:subClassOf obo:NCBITaxon_749416 . obo:OBI_0002512 a rdfs:Class ; rdfs:label "bone marrow specimen" ; rdfs:comment "A specimen that is derived from bone marrow." ; rdfs:subClassOf obo:OBI_0001479 . obo:NCBITaxon_622710 a rdfs:Class ; rdfs:label "Bat coronavirus Hipposideros/GhanaKwam/13/2008" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:GO_0043069 a rdfs:Class ; rdfs:label "negative regulation of programmed cell death" ; rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of programmed cell death, cell death resulting from activation of endogenous cellular processes." ; rdfs:subClassOf obo:GO_0043067 , obo:GO_0060548 . obo:CIDO_0020141 a rdfs:Class ; rdfs:label "FastPlex Triplex SARS-CoV-2 detection kit (RT-Digital PCR)" ; rdfs:seeAlso ; rdfs:subClassOf obo:CIDO_0000454 . obo:CHEBI_32678 a rdfs:Class ; rdfs:label "glutaminate" ; rdfs:comment "An alpha-amino-acid anion that is the conjugate base of glutamine, arising from deprotonation of the carboxy group." ; rdfs:subClassOf obo:CHEBI_33558 . obo:PR_000003030 a rdfs:Class ; rdfs:label "focal adhesion kinase" ; rdfs:comment "A protein that is a translation product of the human PTK2 or PTK2B genes, 1:1 orthologs thereof, or a semi-ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:CHEBI_51569 a rdfs:Class ; rdfs:label "N-acyl-amino acid" ; rdfs:comment "A carboxamide resulting from the formal condensation of a carboxylic acid with the amino group of an amino acid." ; rdfs:subClassOf obo:CHEBI_33575 , obo:CHEBI_37622 , obo:CHEBI_83821 . obo:NCBITaxon_1868634 a rdfs:Class ; rdfs:label "Bat coronavirus/2173/2014/Cynomops planirostris/Brazil" ; rdfs:subClassOf obo:NCBITaxon_366617 . obo:CHEBI_49201 a rdfs:Class ; rdfs:label "anti-ulcer drug" ; rdfs:comment "One of various classes of drugs with different action mechanisms used to treat or ameliorate peptic ulcer or irritation of the gastrointestinal tract." ; rdfs:subClassOf obo:CHEBI_23888 . obo:GO_0032102 a rdfs:Class ; rdfs:label "negative regulation of response to external stimulus" ; rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of a response to an external stimulus." ; rdfs:subClassOf obo:GO_0048583 , obo:GO_0048585 . obo:CL_0000010 a rdfs:Class ; rdfs:label "cultured cell" ; rdfs:comment "A cell in vitro that is or has been maintained or propagated as part of a cell culture." ; rdfs:subClassOf obo:CL_0000578 . obo:NCBITaxon_1805601 a rdfs:Class ; rdfs:label "Alphacoronavirus TT-2016a" ; rdfs:subClassOf obo:NCBITaxon_366617 . obo:PR_P10636 a rdfs:Class ; rdfs:label "microtubule-associated protein tau (human)" ; rdfs:comment "A microtubule-associated protein tau that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000010173 , obo:PR_000029067 . obo:CHEBI_145502 a rdfs:Class ; rdfs:label "(R)-donepezil(1+)" ; rdfs:comment "A piperidinium ion resulting from the protonation of the amino group of (R)-donepezil." ; rdfs:subClassOf obo:CHEBI_48633 . obo:PR_Q00532 a rdfs:Class ; rdfs:label "cyclin-dependent kinase-like 1 (human)" ; rdfs:comment "A cyclin-dependent kinase-like 1 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000005269 , obo:PR_000029067 . obo:CIDO_0001038 a rdfs:Class ; rdfs:label "Sotrovimab" ; rdfs:subClassOf obo:CHEBI_23367 . obo:PR_Q9Y2I6 a rdfs:Class ; rdfs:label "ninein-like protein (human)" ; rdfs:comment "A ninein-like protein that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000029067 , obo:PR_000030656 . obo:OPMI_0000547 a rdfs:Class ; rdfs:label "secondary discharge diagnosis status"@en ; rdfs:subClassOf obo:OPMI_0000546 . obo:CIDO_0020250 a rdfs:Class ; rdfs:label "QuantiVirus SARS-CoV-2 test" ; rdfs:seeAlso ; rdfs:subClassOf obo:CIDO_0000454 . obo:NCBITaxon_1590370 a rdfs:Class ; rdfs:label "Betacoronavirus HKU24" ; rdfs:subClassOf obo:NCBITaxon_2501960 . obo:CIDO_0000686 a rdfs:Class ; rdfs:label "P681R in SARS-CoV-2 S protein" ; rdfs:comment "An AA mutation or AA variant that has mutated an amino acid at position 681 into a arginine in S protein." ; rdfs:subClassOf obo:CIDO_0000592 . obo:CIDO_0000210 a rdfs:Class ; rdfs:label "methylation capping of SARS-CoV-2 pre-mRNA"@en ; rdfs:subClassOf obo:CIDO_0000191 , obo:CIDO_0000197 . obo:NCBITaxon_2520503 a rdfs:Class ; rdfs:label "Alphacoronavirus UKMa1" ; rdfs:subClassOf obo:NCBITaxon_2724758 . obo:CIDO_0020037 a rdfs:Class ; rdfs:label "Avellino SARS-CoV-2/COVID-19 (AvellinoCoV2)" ; rdfs:seeAlso ; rdfs:subClassOf obo:CIDO_0000454 . obo:CHEBI_32552 a rdfs:Class ; rdfs:label "L-lysinium(2+)" ; rdfs:comment "The L-enantiomer of lysinium(2+)." ; rdfs:subClassOf obo:CHEBI_32565 . obo:PR_000008288 a rdfs:Class ; rdfs:label "glycogen synthase kinase-3 beta" ; rdfs:comment "A glycogen synthase kinase 3 that is a translation product of the human GSK3B gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000050019 . obo:NCBITaxon_431320 a rdfs:Class ; rdfs:label "Quail coronavirus Italy/Elvia/2005" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:OPMI_0000485 a rdfs:Class ; rdfs:label "outpatient visit"@en ; rdfs:comment "A vist ocurrence in which a patient attends an outpatient clinic with no plan to stay beyond the duration of the visit." ; rdfs:subClassOf obo:OPMI_0000482 . obo:CHEBI_17418 a rdfs:Class ; rdfs:label "valeric acid" ; rdfs:comment "A straight-chain saturated fatty acid containing five carbon atoms." ; rdfs:subClassOf obo:CHEBI_26666 , obo:CHEBI_39418 . obo:GO_0048519 a rdfs:Class ; rdfs:label "negative regulation of biological process" ; rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule." ; rdfs:subClassOf obo:GO_0050789 . obo:OPMI_0000445 a rdfs:Class ; rdfs:label "biomarker"@en ; rdfs:comment "A material entity that has a measurable quality or process profile(s), which can be used as an indicator of an underlying biological state or identity." ; rdfs:subClassOf obo:BFO_0000040 . a rdfs:Class ; rdfs:label "Age Categories [Disease/Finding]" ; rdfs:subClassOf . obo:PR_P04818 a rdfs:Class ; rdfs:label "thymidylate synthase (human)" ; rdfs:comment "A thymidylate synthase that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000016876 , obo:PR_000029067 . obo:NCBITaxon_694448 a rdfs:Class ; rdfs:label "unidentified human coronavirus" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:OAE_0000439 a rdfs:Class ; rdfs:label "digestive system AE" ; rdfs:comment "an AE that occurs in digestive system." ; rdfs:subClassOf obo:OAE_0000001 . obo:CHEBI_50315 a rdfs:Class ; rdfs:label "chloronium" ; rdfs:subClassOf obo:CHEBI_50313 . obo:PR_000007363 a rdfs:Class ; rdfs:label "fibrillin-2" ; rdfs:comment "A protein that is a translation product of the human FBN2 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:NCBITaxon_204267 a rdfs:Class ; rdfs:label "Melogale moschata" ; rdfs:subClassOf obo:NCBITaxon_204266 . obo:DRON_00061833 a rdfs:Class ; rdfs:label "Hydroxychloroquine Sulfate 200 MG Oral Tablet" ; rdfs:subClassOf obo:DRON_00020600 . obo:CIDO_0000022 a rdf:Property ; rdfs:label "has active ingredient"@en ; rdfs:comment "An object property that represents a relation between a drug and a chemical entity that is the active ingredient of the drug" ; rdfs:range . obo:PR_Q8IUD2 a rdfs:Class ; rdfs:label "ELKS/Rab6-interacting/CAST family member 1 (human)" ; rdfs:comment "An ELKS/Rab6-interacting/CAST family member 1 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000007161 , obo:PR_000029067 . obo:VO_0000173 a rdfs:Class ; rdfs:label "vaccine organism live attenuated" ; rdfs:comment "a virulence of vaccine organism that shows an attenuated pheontype of the organism as the major component of a vaccine." ; rdfs:subClassOf obo:PATO_0002146 . obo:PR_Q96DZ1 a rdfs:Class ; rdfs:label "endoplasmic reticulum lectin 1 (human)" ; rdfs:comment "An endoplasmic reticulum lectin 1 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000029067 , obo:PR_000031965 . obo:PR_O60885 a rdfs:Class ; rdfs:label "bromodomain-containing protein 4 (human)" ; rdfs:comment "A bromodomain-containing protein 4 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000004807 , obo:PR_000029067 . obo:NCBITaxon_230471 a rdfs:Class ; rdfs:label "SARS coronavirus ZJ01" ; rdfs:subClassOf obo:NCBITaxon_694009 . obo:NCBITaxon_249083 a rdfs:Class ; rdfs:label "SARS coronavirus LC1" ; rdfs:subClassOf obo:NCBITaxon_694009 . obo:DOID_591 a rdfs:Class ; rdfs:label "phobic disorder" ; rdfs:comment "An anxiety disorder where fear and anxiety are triggered by a specific stimulus or situation." ; rdfs:subClassOf obo:DOID_2030 . obo:NCBITaxon_681881 a rdfs:Class ; rdfs:label "Kenya bat coronavirus BtKY37" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:CHEBI_26386 a rdfs:Class ; rdfs:label "purine nucleobase" ; rdfs:comment "A nucleobase whose skeleton is derived from purine." ; rdfs:subClassOf obo:CHEBI_18282 , obo:CHEBI_26401 . obo:CHEBI_35344 a rdfs:Class ; rdfs:label "21-hydroxy steroid" ; rdfs:subClassOf obo:CHEBI_35350 . obo:PR_000003507 a rdfs:Class ; rdfs:label "chimeric protein" ; rdfs:comment "A protein that is a translation product of a fusion of two genes." ; rdfs:subClassOf obo:PR_000000001 . obo:DOID_9500 a rdfs:Class ; rdfs:label "leukocyte disease" ; rdfs:comment "A hematopoietic system disease that is located_in white blood cells." ; rdfs:subClassOf obo:DOID_74 . obo:VO_0001060 a rdfs:Class ; rdfs:label "Newcastle disease virus vaccine vector"@en ; rdfs:comment "a viral vaccine vector that uses a NewCastle virus strain" ; rdfs:subClassOf obo:VO_0000610 . obo:CIDO_0020307 a rdfs:Class ; rdfs:label "Texas Department of State Health Services (DSHS) SARS-CoV-2 Assay" ; rdfs:seeAlso ; rdfs:subClassOf obo:CIDO_0000454 . obo:CHEBI_33295 a rdfs:Class ; rdfs:label "diagnostic agent" ; rdfs:comment "A substance administered to aid diagnosis of a disease." ; rdfs:subClassOf obo:CHEBI_52217 . obo:CIDO_0001063 a rdfs:Class ; rdfs:label "SARS-CoV2 orf9c protein binding to human SLC30A6" ; rdfs:comment "SARS-CoV2 orf9c protein binding to human SLC30A6, as evidented by an affinity-purification mass spectrometry experiment" ; rdfs:subClassOf obo:CIDO_0000054 . obo:CIDO_0020260 a rdfs:Class ; rdfs:label "RapidRona Self-Collection Kit" ; rdfs:seeAlso ; rdfs:subClassOf obo:CIDO_0000455 . obo:CIDO_0000776 a rdfs:Class ; rdfs:label "SARS-CoV2 N protein binding to human CSNK2A2" ; rdfs:comment "SARS-CoV2 N protein binding to human CSNK2A2, as evidented by an affinity-purification mass spectrometry experiment" ; rdfs:subClassOf obo:CIDO_0000056 . obo:PR_Q5JRX3 a rdfs:Class ; rdfs:label "presequence protease, mitochondrial (human)" ; rdfs:comment "A presequence protease, mitochondrial that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000012759 , obo:PR_000029067 . obo:NCBITaxon_1381362 a rdfs:Class ; rdfs:label "Bat coronavirus Pikuh/CII_KSA_001/Riyadh/Saudi Arabia/2013" ; rdfs:subClassOf obo:NCBITaxon_366617 . obo:CHEBI_86264 a rdfs:Class ; rdfs:label "rat metabolite" ; rdfs:comment "Any mammalian metabolite produced during a metabolic reaction in rat (Rattus norvegicus)." ; rdfs:subClassOf obo:CHEBI_75768 . obo:CHEBI_32820 a rdfs:Class ; rdfs:label "L-threoninate" ; rdfs:comment "An L-alpha-amino acid anion that is the conjugate base of L-threonine, arising from deprotonation of the carboxy group." ; rdfs:subClassOf obo:CHEBI_32832 , obo:CHEBI_59814 . obo:GO_0000027 a rdfs:Class ; rdfs:label "ribosomal large subunit assembly" ; rdfs:comment "The aggregation, arrangement and bonding together of constituent RNAs and proteins to form the large ribosomal subunit." ; rdfs:subClassOf obo:GO_0022618 . obo:CIDO_0000979 a rdfs:Class ; rdfs:label "SARS-CoV2 orf3a protein binding to human VPS39" ; rdfs:comment "SARS-CoV2 orf3a protein binding to human VPS39, as evidented by an affinity-purification mass spectrometry experiment" ; rdfs:subClassOf obo:CIDO_0000584 . obo:CHEBI_68481 a rdfs:Class ; rdfs:label "mTOR inhibitor" ; rdfs:comment "A protein kinase inhibitor of the mammalian target of rapamycin (mTOR), a protein that regulates cell growth, cell proliferation, cell motility, cell survival, protein synthesis and transcription. mTOR inhibitors are used to prevent transplant rejection and in treatment of cancer." ; rdfs:subClassOf obo:CHEBI_37699 . a rdfs:Class ; rdfs:label "Digoxin [Chemical/Ingredient]" ; rdfs:subClassOf . obo:CIDO_0000841 a rdfs:Class ; rdfs:label "SARS-CoV2 nsp13 protein binding to human GOLGA3" ; rdfs:comment "SARS-CoV2 nsp13 protein binding to human GOLGA3, as evidented by an affinity-purification mass spectrometry experiment" ; rdfs:subClassOf obo:CIDO_0000058 . obo:PR_Q9UEE5 a rdfs:Class ; rdfs:label "serine/threonine-protein kinase 17A (human)" ; rdfs:comment "A serine/threonine-protein kinase 17A that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000015743 , obo:PR_000029067 . obo:PR_000007504 a rdfs:Class ; rdfs:label "centrosomal protein 43" ; rdfs:comment "A protein that is a translation product of the human CEP43 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:NCBITaxon_300188 a rdfs:Class ; rdfs:label "Duck coronavirus" ; rdfs:subClassOf obo:NCBITaxon_694014 . obo:PR_000005950 a rdfs:Class ; rdfs:label "casein kinase II subunit alpha" ; rdfs:comment "A protein that is a translation product of the human CSNK2A1 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:PR_000016055 a rdfs:Class ; rdfs:label "transmembrane anterior posterior transformation protein 1" ; rdfs:comment "A protein that is a translation product of the human TAPT1 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:CHEBI_35470 a rdfs:Class ; rdfs:label "central nervous system drug" ; rdfs:comment "A class of drugs producing both physiological and psychological effects through a variety of mechanisms involving the central nervous system." ; rdfs:subClassOf obo:CHEBI_23888 . obo:CHEBI_39205 a rdfs:Class ; rdfs:label "dibenzopyrrole" ; rdfs:subClassOf obo:CHEBI_26979 , obo:CHEBI_38101 . obo:GO_0010517 a rdfs:Class ; rdfs:label "regulation of phospholipase activity" ; rdfs:comment "Any process that modulates the frequency, rate or extent of phospholipase activity, the hydrolysis of a phospholipid." ; rdfs:subClassOf obo:GO_0060191 . obo:CIDO_0000070 a rdfs:Class ; rdfs:label "SARS-CoV-2 Nsp11 protein interaction with host protein"@en ; rdfs:comment "A molecular interaction that has participant of the SARS-CoV-2 Nsp11 protein and a host protein" ; rdfs:subClassOf obo:CIDO_0000348 . obo:NCBITaxon_1289552 a rdfs:Class ; rdfs:label "Coronavirus Mex_CoV-6" ; rdfs:subClassOf obo:NCBITaxon_366617 . obo:CHEBI_38785 a rdfs:Class ; rdfs:label "morpholines" ; rdfs:comment "Any compound containing morpholine as part of its structure." ; rdfs:subClassOf obo:CHEBI_46952 . obo:GO_0032496 a rdfs:Class ; rdfs:label "response to lipopolysaccharide" ; rdfs:comment "Any process that results in a change in state or activity of an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lipopolysaccharide stimulus; lipopolysaccharide is a major component of the cell wall of gram-negative bacteria." ; rdfs:subClassOf obo:GO_0002237 , obo:GO_0033993 , obo:GO_1901700 . a rdfs:Class ; rdfs:label "Nucleic Acid Synthesis Inhibitors [MoA]" ; rdfs:subClassOf . obo:CIDO_0000362 a rdfs:Class ; rdfs:label "angiotensin II receptor"@en ; rdfs:comment "The angiotensin II receptor is a member of the class of G protein-coupled receptors with angiotensin II as their ligands. They are important in the renin–angiotensin system: they are responsible for the signal transduction of the vasoconstricting stimulus of the main effector hormone, angiotensin II." ; rdfs:subClassOf obo:PR_000000001 . obo:VO_0000574 a rdfs:Class ; rdfs:label "route of administration" ; rdfs:comment "a path that is located in gross anatomical part of an organism (e.g., human) and is used for administering a vaccine, a drug, fluid, poison, or other substance into the body. " ; rdfs:seeAlso , ; rdfs:subClassOf obo:BFO_0000029 . obo:PR_000013603 a rdfs:Class ; rdfs:label "Ras-related protein Rab-2A" ; rdfs:comment "A protein that is a translation product of the human RAB2A gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:GO_0006952 a rdfs:Class ; rdfs:label "defense response" ; rdfs:comment "Reactions, triggered in response to the presence of a foreign body or the occurrence of an injury, which result in restriction of damage to the organism attacked or prevention/recovery from the infection caused by the attack." ; rdfs:subClassOf obo:GO_0006950 . obo:PR_Q9C098 a rdfs:Class ; rdfs:label "serine/threonine-protein kinase DCLK3 (human)" ; rdfs:comment "A serine/threonine-protein kinase DCLK3 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000006312 , obo:PR_000029067 . a rdfs:Class ; rdfs:label "Inorganic Chemicals [Chemical/Ingredient]" ; rdfs:subClassOf . a rdfs:Class ; rdfs:label "Basal Ganglia Diseases [Disease/Finding]" ; rdfs:subClassOf . obo:GO_0060048 a rdfs:Class ; rdfs:label "cardiac muscle contraction" ; rdfs:comment "Muscle contraction of cardiac muscle tissue." ; rdfs:subClassOf obo:GO_0006936 . obo:CHEBI_149548 a rdfs:Class ; rdfs:label "emetine(2+)" ; rdfs:comment "An ammonium ion derivative obtained from protonation of the nitrogens of emetine. It is the major species at pH 7.3." ; rdfs:subClassOf obo:CHEBI_35274 . obo:PR_O75716 a rdfs:Class ; rdfs:label "serine/threonine-protein kinase 16 (human)" ; rdfs:comment "A serine/threonine-protein kinase 16 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000015742 , obo:PR_000029067 . a rdfs:Class ; rdfs:label "Thiazoles [Chemical/Ingredient]" ; rdfs:subClassOf , . obo:PR_000030281 a rdfs:Class ; rdfs:label "probable ribosome biogenesis protein RLP24" ; rdfs:comment "A protein that is a translation product of the human RSL24D1 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . a rdfs:Class ; rdfs:label "Bridged Compounds [Chemical/Ingredient]" ; rdfs:subClassOf , . obo:OPMI_0000514 a rdfs:Class ; rdfs:label "death diagnosis status"@en ; rdfs:comment "The status of being diagnosed as death" ; rdfs:subClassOf obo:OPMI_0000533 . obo:CIDO_0020101 a rdfs:Class ; rdfs:label "covidSHIELD" ; rdfs:seeAlso ; rdfs:subClassOf obo:CIDO_0000454 . obo:PR_P51813 a rdfs:Class ; rdfs:label "cytoplasmic tyrosine-protein kinase BMX (human)" ; rdfs:comment "A cytoplasmic tyrosine-protein kinase BMX that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000002200 , obo:PR_000029067 . a rdfs:Class ; rdfs:label "Decreased Lymphocyte Cell Production [PE]" ; rdfs:subClassOf . a rdfs:Class ; rdfs:label "Piperidones [Chemical/Ingredient]" ; rdfs:subClassOf . obo:NCBITaxon_1437010 a rdfs:Class ; rdfs:label "Boreoeutheria" ; rdfs:subClassOf obo:NCBITaxon_40674 , obo:NCBITaxon_9347 . a rdfs:Class ; rdfs:label "Thrombophlebitis [Disease/Finding]" ; rdfs:subClassOf , . obo:NCBITaxon_454952 a rdfs:Class ; rdfs:label "Feline coronavirus UU4" ; rdfs:subClassOf obo:NCBITaxon_12663 . obo:CHEBI_29537 a rdfs:Class ; rdfs:label "avermectin B1b" ; rdfs:subClassOf obo:CHEBI_50344 . obo:IAO_0000028 a rdfs:Class ; rdfs:label "symbol"@en ; rdfs:comment "An information content entity that is a mark(s) or character(s) used as a conventional representation of another entity."@en ; rdfs:subClassOf obo:IAO_0000030 . obo:CHEBI_17295 a rdfs:Class ; rdfs:label "L-phenylalanine" ; rdfs:comment "The L-enantiomer of phenylalanine." ; rdfs:subClassOf obo:CHEBI_15705 , obo:CHEBI_28044 , obo:CHEBI_73690 , obo:CHEBI_83813 . obo:CHEBI_75767 a rdfs:Class ; rdfs:label "animal metabolite" ; rdfs:comment "Any eukaryotic metabolite produced during a metabolic reaction in animals that include diverse creatures from sponges, insects to mammals." ; rdfs:subClassOf obo:CHEBI_75763 . obo:CHEBI_107432 a rdfs:Class ; rdfs:label "(3R,3aS,7R,7aS)-3-[4-[4-(dimethylamino)phenyl]-2-fluorophenyl]-7-methyl-2-(phenylmethyl)-3a,6,7,7a-tetrahydro-3H-isoindol-1-one" ; rdfs:subClassOf obo:CHEBI_22888 . obo:VO_0005399 a rdfs:Class ; rdfs:label "Osvid-19"@en ; rdfs:comment "A SARS-CoV-2 inactivated vaccine developed by Osve Pharmaceutical Company." ; rdfs:subClassOf obo:VO_0005201 . obo:CHEBI_26547 a rdfs:Class ; rdfs:label "rhamnoside" ; rdfs:subClassOf obo:CHEBI_35315 . obo:CHEBI_2571 a rdfs:Class ; rdfs:label "aliphatic alcohol" ; rdfs:comment "An alcohol derived from an aliphatic compound." ; rdfs:subClassOf obo:CHEBI_30879 . a rdfs:Class ; rdfs:label "Hypotension [Disease/Finding]" ; rdfs:subClassOf . obo:PR_000003200 a rdfs:Class ; rdfs:label "calcium/calmodulin-dependent protein kinase type II subunit beta" ; rdfs:comment "A calcium/calmodulin-dependent protein kinase type II chain that is a translation product of the human CAMK2B gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000003197 . obo:CHEBI_30353 a rdfs:Class ; rdfs:label "isopropyl group" ; rdfs:subClassOf obo:CHEBI_22323 , obo:CHEBI_50325 . a rdfs:Class ; rdfs:label "Porphyrias, Hepatic [Disease/Finding]" ; rdfs:subClassOf , , . obo:PR_000013075 a rdfs:Class ; rdfs:label "peptidyl-prolyl cis-trans isomerase A" ; rdfs:comment "A protein that is a translation product of the human PPIA gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:OPMI_0000511 a rdfs:Class ; rdfs:label "procedure end datetime"@en ; rdfs:comment "The date and time when a procedure ends" ; rdfs:subClassOf obo:OPMI_0000507 . obo:CIDO_0020139 a rdfs:Class ; rdfs:label "ExProbe SARS-CoV-2 Testing Kit" ; rdfs:seeAlso ; rdfs:subClassOf obo:CIDO_0000454 . obo:CIDO_0000434 a rdfs:Class ; rdfs:label "motivation"@en ; rdfs:comment "A disposition that exists in an organism or virus and motivates the organism or virus to act or behave to achieve a specific outcome." ; rdfs:subClassOf obo:BFO_0000016 . obo:CHEBI_28616 a rdfs:Class ; rdfs:label "carbamic acid" ; rdfs:comment "A one-carbon compound that is ammonia in which one of the hydrogens is replaced by a carboxy group. Although carbamic acid derivatives are common, carbamic acid itself has never been synthesised." ; rdfs:subClassOf obo:CHEBI_35352 , obo:CHEBI_35605 , obo:CHEBI_64708 . obo:PR_O95260 a rdfs:Class ; rdfs:label "arginyl-tRNA--protein transferase 1 (human)" ; rdfs:comment "An arginyl-tRNA--protein transferase 1 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000004396 , obo:PR_000029067 . obo:PR_000012845 a rdfs:Class ; rdfs:label "5'-3' exonuclease PLD3" ; rdfs:comment "A protein that is a translation product of the human PLD3 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:PR_000012784 a rdfs:Class ; rdfs:label "membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase" ; rdfs:comment "A protein that is a translation product of the human PKMYT1 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . a rdfs:Class ; rdfs:label "Increased Central Nervous System Norepinephrine Activity [PE]" ; rdfs:subClassOf . obo:CHEBI_57981 a rdfs:Class ; rdfs:label "D-phenylalanine zwitterion" ; rdfs:comment "A D-alpha-amino acid zwitterion that is D-phenylalanine in which a proton has been transferred from the carboxy group to the amino group. It is the major species at pH 7.3." ; rdfs:subClassOf obo:CHEBI_59871 . obo:CHEBI_36709 a rdfs:Class ; rdfs:label "aminoquinoline" ; rdfs:comment "Any member of the class of quinolines in which the quinoline skeleton is substituted by one or more amino or substituted-amino groups." ; rdfs:subClassOf obo:CHEBI_26513 , obo:CHEBI_33860 . obo:PR_000012871 a rdfs:Class ; rdfs:label "serine/threonine-protein kinase PLK2" ; rdfs:comment "A protein that is a translation product of the human PLK2 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:PR_P43405 a rdfs:Class ; rdfs:label "tyrosine-protein kinase SYK (human)" ; rdfs:comment "A tyrosine-protein kinase SYK that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000003065 , obo:PR_000029067 . obo:BFO_0000011 a rdfs:Class ; rdfs:label "spatiotemporal region"@en ; rdfs:subClassOf obo:BFO_0000003 . obo:BFO_0000126 a rdf:Property ; rdfs:label "has spatiotemporal occupant"@en ; rdfs:domain obo:BFO_0000011 ; rdfs:range obo:BFO_0000003 . obo:BFO_0000153 a rdf:Property ; rdfs:label "projects onto temporal region"@en ; rdfs:domain obo:BFO_0000011 ; rdfs:range obo:BFO_0000008 ; rdfs:subPropertyOf obo:BFO_0000108 . obo:BFO_0000151 a rdf:Property ; rdfs:label "projects onto spatial region at some time"@en ; rdfs:domain obo:BFO_0000011 ; rdfs:range obo:BFO_0000006 . obo:GO_0007166 a rdfs:Class ; rdfs:label "cell surface receptor signaling pathway" ; rdfs:comment "The series of molecular signals initiated by activation of a receptor on the surface of a cell. The pathway begins with binding of an extracellular ligand to a cell surface receptor, or for receptors that signal in the absence of a ligand, by ligand-withdrawal or the activity of a constitutively active receptor. The pathway ends with regulation of a downstream cellular process, e.g. transcription." ; rdfs:subClassOf obo:GO_0007165 . obo:CIDO_0000691 a rdfs:Class ; rdfs:label "R190S in SARS-CoV-2 S protein" ; rdfs:comment "An AA mutation or AA variant that has mutated an amino acid at position 190 into a serine" ; rdfs:subClassOf obo:CIDO_0000594 . obo:NCBITaxon_1515640 a rdfs:Class ; rdfs:label "Mallard coronavirus" ; rdfs:subClassOf obo:NCBITaxon_749416 . obo:NCBITaxon_1897078 a rdfs:Class ; rdfs:label "Bat coronavirus Myo.rip/259/BRA/2013" ; rdfs:subClassOf obo:NCBITaxon_366617 . obo:GO_0046486 a rdfs:Class ; rdfs:label "glycerolipid metabolic process" ; rdfs:comment "The chemical reactions and pathways involving glycerolipids, any lipid with a glycerol backbone. Diacylglycerol and phosphatidate are key lipid intermediates of glycerolipid biosynthesis." ; rdfs:subClassOf obo:GO_0044255 . obo:NCBITaxon_393767 a rdfs:Class ; rdfs:label "Bat coronavirus 1A" ; rdfs:subClassOf obo:NCBITaxon_694000 . obo:GO_0030335 a rdfs:Class ; rdfs:label "positive regulation of cell migration" ; rdfs:comment "Any process that activates or increases the frequency, rate or extent of cell migration." ; rdfs:subClassOf obo:GO_2000145 , obo:GO_2000147 . a rdfs:Class ; rdfs:label "Trematode Infections [Disease/Finding]" ; rdfs:subClassOf . obo:CHEBI_36359 a rdfs:Class ; rdfs:label "phosphorus oxoacid derivative" ; rdfs:subClassOf obo:CHEBI_33241 , obo:CHEBI_36360 . obo:CIDO_0000553 a rdfs:Class ; rdfs:label "KLITTACNGISVTQT" ; rdfs:comment "A coronavirus epitope that is part of some S protein from HCoV HKU1 composed of the following amino acids KLITTACNGISVTQT" ; rdfs:subClassOf obo:CIDO_0000450 . obo:CHEBI_34995 a rdfs:Class ; rdfs:label "teicoplanin A2-1" ; rdfs:comment "A teicoplanin A2 that has (4Z)-dec-4-enoyl as the variable N-acyl group." ; rdfs:subClassOf obo:CHEBI_34994 . obo:CHEBI_35506 a rdfs:Class ; rdfs:label "alkaloid fundamental parent" ; rdfs:subClassOf obo:CHEBI_35507 . obo:CHEBI_32563 a rdfs:Class ; rdfs:label "lysinate" ; rdfs:comment "An alpha-amino-acid anion that is the conjugate base of lysine, arising from deprotonation of the carboxy group." ; rdfs:subClassOf obo:CHEBI_33558 . obo:CHEBI_35969 a rdfs:Class ; rdfs:label "3-hydroxy monocarboxylic acid" ; rdfs:comment "A hydroxy monocarboxylic acid that has a hydroxy group beta to the carboxy group." ; rdfs:subClassOf obo:CHEBI_35868 , obo:CHEBI_61355 . obo:NCBITaxon_267389 a rdfs:Class ; rdfs:label "SARS coronavirus Sin3725V" ; rdfs:subClassOf obo:NCBITaxon_694009 . obo:CIDO_0000033 a rdfs:Class ; rdfs:label "COVID-19 diagnostic process by chest imaging"@en ; rdfs:comment "A COVID-19 diagnostic process that is performed by chest imaging. Thoracic imaging with chest radiography (CXR) and computed tomography (CT) are key tools for pulmonary disease diagnosis and management." ; rdfs:subClassOf obo:CIDO_0000424 . obo:NCBITaxon_1508221 a rdfs:Class ; rdfs:label "Anlong Ms bat coronavirus" ; rdfs:subClassOf obo:NCBITaxon_2691591 . obo:CHEBI_15705 a rdfs:Class ; rdfs:label "L-alpha-amino acid" ; rdfs:comment "Any alpha-amino acid having L-configuration at the alpha-carbon." ; rdfs:subClassOf obo:CHEBI_33704 . obo:BFO_0000040 a rdfs:Class ; rdfs:label "material entity"@en ; rdfs:comment "An independent continuant that is spatially extended whose identity is independent of that of other entities and can be maintained through time."@en ; rdfs:subClassOf obo:BFO_0000004 . obo:OBI_0400168 a rdfs:Class ; rdfs:label "microtome" ; rdfs:comment "A microtome is a mechanical instrument used to cut biological specimens into very thin segments for further treatment (e.g. ISH) and ultimately microscopic or histologic examination. Most microtomes provide cooling facilities (cryo-microtome) and use a steel blade to cut a slice of defined thickness. Some are automatic, and some are driven by hand." ; rdfs:subClassOf obo:OBI_0000932 . obo:VO_0005418 a rdfs:Class ; rdfs:label "authorized COVID-19 virus-like particle vaccine"@en ; rdfs:subClassOf obo:VO_0005205 , obo:VO_0005264 . obo:OBI_0001936 a rdfs:Class ; rdfs:label "molecular-labeled material" ; rdfs:comment "a material entity that is the specified output of an addition of molecular label process that aims to label some molecular target to allow for its detection in a detection of molecular label assay" ; rdfs:subClassOf obo:BFO_0000040 , obo:OBI_0000047 . a rdfs:Class ; rdfs:label "Digestive/GI System Activity Alteration [PE]" ; rdfs:subClassOf . obo:CIDO_0000251 a rdfs:Class ; rdfs:label "coronavirus survival in host cell"@en ; rdfs:subClassOf obo:CIDO_0000198 . obo:NCBITaxon_2691597 a rdfs:Class ; rdfs:label "Hipposideros pomona bat coronavirus HKU10-related" ; rdfs:subClassOf obo:NCBITaxon_2691596 . a rdfs:Class ; rdfs:label "2-Aminopurine [Chemical/Ingredient]" ; rdfs:subClassOf . obo:CHEBI_75603 a rdfs:Class ; rdfs:label "EC 6.* (ligase) inhibitor" ; rdfs:comment "Any enzyme inhibitor that interferes with the action of a ligase (EC 6.*.*.*). Ligases are enzymes that catalyse the joining of two molecules with concomitant hydrolysis of the diphosphate bond in ATP or a similar triphosphate." ; rdfs:subClassOf obo:CHEBI_23924 . obo:PR_P61962 a rdfs:Class ; rdfs:label "DDB1- and CUL4-associated factor 7 (human)" ; rdfs:comment "A DDB1- and CUL4-associated factor 7 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000029067 , obo:PR_000029377 . obo:NCBITaxon_1487701 a rdfs:Class ; rdfs:label "Myotis daubentonii coronavirus" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:CIDO_0000832 a rdfs:Class ; rdfs:label "SARS-CoV2 nsp13 protein binding to human CEP68" ; rdfs:comment "SARS-CoV2 nsp13 protein binding to human CEP68, as evidented by an affinity-purification mass spectrometry experiment" ; rdfs:subClassOf obo:CIDO_0000058 . obo:NCBITaxon_1289545 a rdfs:Class ; rdfs:label "Coronavirus Mex_CoV-10" ; rdfs:subClassOf obo:NCBITaxon_696098 . obo:CHEBI_50267 a rdfs:Class ; rdfs:label "protective agent" ; rdfs:comment "Synthetic or natural substance which is given to prevent a disease or disorder or are used in the process of treating a disease or injury due to a poisonous agent." ; rdfs:subClassOf obo:CHEBI_23888 . a rdfs:Class ; rdfs:label "Niclosamide [Chemical/Ingredient]" ; rdfs:subClassOf . obo:CIDO_0000713 a rdfs:Class ; rdfs:label "SARS-CoV2 E protein binding to human BRD4" ; rdfs:comment "SARS-CoV2 E protein binding to human BRD4, as evidented by an affinity-purification mass spectrometry experiment" ; rdfs:subClassOf obo:CIDO_0000046 . obo:GO_0006413 a rdfs:Class ; rdfs:label "translational initiation" ; rdfs:comment "The process preceding formation of the peptide bond between the first two amino acids of a protein. This includes the formation of a complex of the ribosome, mRNA or circRNA, and an initiation complex that contains the first aminoacyl-tRNA." ; rdfs:subClassOf obo:GO_0044237 . obo:PR_000000047 a rdfs:Class ; rdfs:label "TGF-beta receptor type-1" ; rdfs:comment "A TGF-beta superfamily receptor type-1 that is a translation product of the human TGFBR1 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000006 . obo:NCBITaxon_2042538 a rdfs:Class ; rdfs:label "Coronavirus PREDICT CoV-11" ; rdfs:subClassOf obo:NCBITaxon_696098 . obo:NCBITaxon_1699349 a rdfs:Class ; rdfs:label "Rhinolophus Bat Alphacoronavirus strain MJ_69C" ; rdfs:subClassOf obo:NCBITaxon_366617 . obo:CHEBI_33402 a rdfs:Class ; rdfs:label "sulfur oxoacid" ; rdfs:subClassOf obo:CHEBI_26835 , obo:CHEBI_33484 . obo:NCBITaxon_1269307 a rdfs:Class ; rdfs:label "Coronavirus BtCoV/KCR293/Ano_geo/CRC/2010" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:CHEBI_24532 a rdfs:Class ; rdfs:label "organic heterocyclic compound" ; rdfs:comment "A cyclic compound having as ring members atoms of carbon and at least of one other element." ; rdfs:subClassOf obo:CHEBI_33285 , obo:CHEBI_33832 , obo:CHEBI_5686 . obo:CIDO_0020271 a rdfs:Class ; rdfs:label "SARS-CoV-2 Fluorescent PCR Kit" ; rdfs:seeAlso ; rdfs:subClassOf obo:CIDO_0000454 . obo:CIDO_0000105 a rdfs:Class ; rdfs:label "interruption to SARS-CoV cell invasion"@en ; rdfs:comment "A process that interrupts SARS-CoV viral entry to host cell" ; rdfs:subClassOf obo:CIDO_0000102 . obo:CIDO_0000783 a rdfs:Class ; rdfs:label "SARS-CoV2 N protein binding to human MOV10" ; rdfs:comment "SARS-CoV2 N protein binding to human MOV10, as evidented by an affinity-purification mass spectrometry experiment" ; rdfs:subClassOf obo:CIDO_0000056 . obo:OBI_0000927 a rdfs:Class ; rdfs:label "lyophilization storage" ; rdfs:comment "a storage process with input material entity and output freeze dried material for long time storage" ; rdfs:subClassOf obo:OBI_0302893 . obo:PR_P35968 a rdfs:Class ; rdfs:label "vascular endothelial growth factor receptor 2 (human)" ; rdfs:comment "A vascular endothelial growth factor receptor 2 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000002112 , obo:PR_000029067 . obo:PR_000007260 a rdfs:Class ; rdfs:label "exosome complex component RRP40" ; rdfs:comment "A protein that is a translation product of the human EXOSC3 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:CHEBI_58570 a rdfs:Class ; rdfs:label "D-tyrosine zwitterion" ; rdfs:comment "A D-alpha-amino acid zwitterion that is D-tyrosine in which a proton has been transferred from the carboxy group to the amino group. It is the major species at pH 7.3." ; rdfs:subClassOf obo:CHEBI_59871 . obo:NCBITaxon_1346317 a rdfs:Class ; rdfs:label "Betacoronavirus BtCoV/Rhi_hip/Slo57/SLO/2009" ; rdfs:subClassOf obo:NCBITaxon_696098 . obo:OPMI_0000525 a rdfs:Class ; rdfs:label "provenance of condition occurrence record"@en ; rdfs:comment "A provenance of record that determines the provenance of the Condition record, as in whether the condition was from an EHR system, insurance claim, registry, or other sources." ; rdfs:subClassOf obo:OPMI_0000512 . obo:CIDO_0001146 a rdfs:Class ; rdfs:label "SARS-CoV-2 S1 RBD protein amino acid deletion"@en ; rdfs:comment "A SARS-CoV-2 protein AA deletion that affected a SARS-CoV-2 S protein in the RBD domain." ; rdfs:subClassOf obo:CIDO_0001145 . obo:CHEBI_71218 a rdfs:Class ; rdfs:label "pazopanib(1+)" ; rdfs:comment "An organic cation that is the conjugate acid of pazopanib." ; rdfs:subClassOf obo:CHEBI_25697 . obo:DOID_0070092 a rdfs:Class ; rdfs:label "schizophrenia 16" ; rdfs:comment "A schizophrenia that has_material_basis_in a mutation on chromosome 7q36.3." ; rdfs:subClassOf obo:DOID_0050177 , obo:DOID_5419 . obo:VO_0005125 a rdfs:Class ; rdfs:label "inactivated whole (formalin and UV radiation) SARS-CoV vaccine" ; rdfs:comment "A SARS inactivated vaccine made from inactivated whole virus by formalin and Ultraviolet radiation, hence Double Inactivated (DI) Vaccine" ; rdfs:subClassOf obo:VO_0012183 . obo:CHEBI_24580 a rdfs:Class ; rdfs:label "hexenoic acid" ; rdfs:comment "A C6, medium-chain fatty acid carrying a double bond at any position along the main chain." ; rdfs:subClassOf obo:CHEBI_25413 , obo:CHEBI_59554 . a rdfs:Class ; rdfs:label "Neoplasms, Connective and Soft Tissue [Disease/Finding]" ; rdfs:subClassOf . a rdfs:Class ; rdfs:label "Decreased Immunologically Active Molecule Activity [PE]" ; rdfs:subClassOf , . obo:UBERON_0010000 a rdfs:Class ; rdfs:label "multicellular anatomical structure" ; rdfs:comment "An anatomical structure that has more than one cell as a part." ; rdfs:subClassOf obo:UBERON_0000061 . obo:CIDO_0000989 a rdfs:Class ; rdfs:label "SARS-CoV2 orf8 protein binding to human CHPF2" ; rdfs:comment "SARS-CoV2 orf8 protein binding to human CHPF2, as evidented by an affinity-purification mass spectrometry experiment" ; rdfs:subClassOf obo:CIDO_0000051 . obo:CHEBI_60251 a rdfs:Class ; rdfs:label "guanidinium ion" ; rdfs:comment "R = C or H. The iminium ion resulting from the protonation of one of the imine nitrogens of guanidine or its derivatives." ; rdfs:subClassOf obo:CHEBI_35286 . obo:NCBITaxon_864616 a rdfs:Class ; rdfs:label "Bat coronavirus BR98-52/BGR/2008" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:CHEBI_35544 a rdfs:Class ; rdfs:label "EC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitor" ; rdfs:comment "A compound or agent that combines with cyclooxygenases (EC 1.14.99.1) and thereby prevents its substrate-enzyme combination with arachidonic acid and the formation of icosanoids, prostaglandins, and thromboxanes." ; rdfs:subClassOf obo:CHEBI_76840 . obo:NCBITaxon_389241 a rdfs:Class ; rdfs:label "Bat coronavirus (BtCoV/365A/2005)" ; rdfs:subClassOf obo:NCBITaxon_389126 . obo:OBI_0000070 a rdfs:Class ; rdfs:label "assay"@en ; rdfs:comment "A planned process with the objective to produce information about the material entity that is the evaluant, by physically examining it or its proxies."@en ; rdfs:subClassOf obo:OBI_0000011 . obo:GO_0006518 a rdfs:Class ; rdfs:label "peptide metabolic process" ; rdfs:comment "The chemical reactions and pathways involving peptides, compounds of two or more amino acids where the alpha carboxyl group of one is bound to the alpha amino group of another." ; rdfs:subClassOf obo:GO_0043603 , obo:GO_1901564 . obo:HP_0012639 a rdfs:Class ; rdfs:label "Abnormal nervous system morphology" ; rdfs:comment "A structural anomaly of the nervous system." ; rdfs:subClassOf obo:HP_0000707 . obo:GO_0045070 a rdfs:Class ; rdfs:label "positive regulation of viral genome replication" ; rdfs:comment "Any process that activates or increases the frequency, rate or extent of viral genome replication." ; rdfs:subClassOf obo:GO_0045069 , obo:GO_0048524 . obo:NCBITaxon_1788481 a rdfs:Class ; rdfs:label "Miniopterus bat coronavirus BtCoV/4068-1" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:CIDO_0000809 a rdfs:Class ; rdfs:label "SARS-CoV2 nsp12 protein binding to human PLEKHA5" ; rdfs:comment "SARS-CoV2 nsp12 protein binding to human PLEKHA5, as evidented by an affinity-purification mass spectrometry experiment" ; rdfs:subClassOf obo:CIDO_0000057 . a rdfs:Class ; rdfs:label "Corpus Luteum Hormones [Chemical/Ingredient]" ; rdfs:subClassOf . obo:CHEBI_22689 a rdfs:Class ; rdfs:label "bafilomycin A1" ; rdfs:comment "The most used of the bafilomycins, a family of toxic macrolide antibiotics derived from Streptomyces griseus." ; rdfs:subClassOf obo:CHEBI_25105 , obo:CHEBI_46942 , obo:CHEBI_59780 . obo:CHEBI_66873 a rdfs:Class ; rdfs:label "C4-dicarboxylic acid" ; rdfs:comment "Any dicarboxylic acid that contains four carbon atoms." ; rdfs:subClassOf obo:CHEBI_35692 . obo:CIDO_0000264 a rdfs:Class ; rdfs:label "COVID-19 immunofluorescence serological diagnostic assay"@en ; rdfs:comment "A COVID-19 serological assay that tests the serum from the blood specimen by an Immunofluorescence assay (IFA)" ; rdfs:subClassOf obo:CIDO_0000262 . a rdfs:Class ; rdfs:label "Decreased Organized Electrical Activity [PE]" ; rdfs:subClassOf . obo:PR_000010145 a rdfs:Class ; rdfs:label "mitogen-activated protein kinase kinase kinase kinase 3" ; rdfs:comment "A protein that is a translation product of the human MAP4K3 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:CHEBI_18274 a rdfs:Class ; rdfs:label "2'-deoxyribonucleoside" ; rdfs:subClassOf obo:CHEBI_23636 , obo:CHEBI_47018 . a rdfs:Class ; rdfs:label "Cryptosporidiosis [Disease/Finding]" ; rdfs:subClassOf , , . obo:CHEBI_20854 a rdfs:Class ; rdfs:label "ATP synthase inhibitor" ; rdfs:comment "A mitochondrial respiratory-chain inhibitor that interferes with the action of ATP synthase." ; rdfs:subClassOf obo:CHEBI_25355 , obo:CHEBI_73216 . obo:CHEBI_90705 a rdfs:Class ; rdfs:label "SB 203580" ; rdfs:comment "A member of the class of imidazoles carrying 4-methylsulfinylphenyl, 4-pyridyl and 4-fluorophenyl substituents at positions 2, 4 and 5 respectively. An inhibitor of mitogen-activated protein kinase." ; rdfs:subClassOf obo:CHEBI_22063 , obo:CHEBI_24780 , obo:CHEBI_26421 , obo:CHEBI_83575 . obo:CHEBI_35297 a rdfs:Class ; rdfs:label "acene" ; rdfs:comment "A polycyclic aromatic hydrocarbon consisting of fused benzene rings in a rectilinear arrangement." ; rdfs:subClassOf obo:CHEBI_35296 , obo:CHEBI_51269 . obo:GO_0007197 a rdfs:Class ; rdfs:label "adenylate cyclase-inhibiting G protein-coupled acetylcholine receptor signaling pathway" ; rdfs:comment "An adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway initiated by acetylcholine binding to its receptor, and ending with the regulation of a downstream cellular process." ; rdfs:subClassOf obo:GO_0007193 , obo:GO_0007213 . obo:CHEBI_36333 a rdfs:Class ; rdfs:label "local anaesthetic" ; rdfs:comment "Any member of a group of drugs that reversibly inhibit the propagation of signals along nerves. Wide variations in potency, stability, toxicity, water-solubility and duration of action determine the route used for administration, e.g. topical, intravenous, epidural or spinal block." ; rdfs:subClassOf obo:CHEBI_38867 . obo:CHEBI_22527 a rdfs:Class ; rdfs:label "aminopurine" ; rdfs:comment "Any purine having at least one amino substituent." ; rdfs:subClassOf obo:CHEBI_26401 . obo:CHEBI_35664 a rdfs:Class ; rdfs:label "EC 1.1.1.34/EC 1.1.1.88 (hydroxymethylglutaryl-CoA reductase) inhibitor" ; rdfs:comment "Any EC 1.1.1.* (oxidoreductase acting on donor CH-OH group, NAD(+) or NADP(+) acceptor) inhibitor that inhibits HMG-CoA reductases. Hydroxymethylglutaryl-CoA reductase inhibitors have been shown to lower directly cholesterol synthesis. The Enzyme Commission designation is EC 1.1.1.34 for the NADPH-dependent enzyme and EC 1.1.1.88 for an NADH-dependent enzyme." ; rdfs:subClassOf obo:CHEBI_76835 . obo:NCBITaxon_1508228 a rdfs:Class ; rdfs:label "Wencheng Sm shrew coronavirus" ; rdfs:subClassOf obo:NCBITaxon_366617 . obo:PR_Q08345 a rdfs:Class ; rdfs:label "epithelial discoidin domain-containing receptor 1 (human)" ; rdfs:comment "A discoidin domain-containing receptor 1 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000001445 , obo:PR_000029067 . obo:CHEBI_16811 a rdfs:Class ; rdfs:label "methionine" ; rdfs:comment "A sulfur-containing amino acid that is butyric acid bearing an amino substituent at position 2 and a methylthio substituent at position 4." ; rdfs:subClassOf obo:CHEBI_26834 , obo:CHEBI_33704 . obo:PR_000037023 a rdfs:Class ; rdfs:label "influenzavirus M gene translation product" ; rdfs:comment "A protein that is a translation product of the Influenza A virus M gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:CHEBI_17562 a rdfs:Class ; rdfs:label "cytidine" ; rdfs:comment "A pyrimidine nucleoside in which cytosine is attached to ribofuranose via a beta-N(1)-glycosidic bond." ; rdfs:subClassOf obo:CHEBI_23524 . obo:CHEBI_26834 a rdfs:Class ; rdfs:label "sulfur-containing amino acid" ; rdfs:subClassOf obo:CHEBI_33576 , obo:CHEBI_33709 . obo:PR_000050265 a rdfs:Class ; rdfs:label "ORF7a protein, signal peptide removed form (SARS-CoV-2)" ; rdfs:comment "An ORF7a protein (SARS-CoV-2) that has had the signal peptide removed. UniProtKB:P0DTC7, 16-121." ; rdfs:subClassOf obo:PR_P0DTC7 . obo:NCBITaxon_2708335 a rdfs:Class ; rdfs:label "Pangolin coronavirus" ; rdfs:subClassOf obo:NCBITaxon_2720068 . obo:VO_0000093 a rdfs:Class ; rdfs:label "mineral salt vaccine adjuvant" ; rdfs:comment "a vaccine adjuvant that is formed as a mineral salt." ; rdfs:subClassOf obo:VO_0000580 . obo:PR_000012244 a rdfs:Class ; rdfs:label "serine/threonine-protein kinase PAK 6" ; rdfs:comment "A protein that is a translation product of the human PAK6 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:NCBITaxon_2042696 a rdfs:Class ; rdfs:label "Bat coronavirus 1" ; rdfs:subClassOf obo:NCBITaxon_366617 . obo:NCBITaxon_1699322 a rdfs:Class ; rdfs:label "Myotis Bat Alphacoronavirus strain YNXY_11C" ; rdfs:subClassOf obo:NCBITaxon_366617 . obo:CIDO_0020295 a rdfs:Class ; rdfs:label "Smart Detect SARS-CoV-2 rRT-PCR Kit" ; rdfs:seeAlso ; rdfs:subClassOf obo:CIDO_0000454 . obo:NCBITaxon_33554 a rdfs:Class ; rdfs:label "Carnivora" ; rdfs:subClassOf obo:NCBITaxon_314145 . obo:CIDO_0000815 a rdfs:Class ; rdfs:label "SARS-CoV2 nsp12 protein binding to human SLU7" ; rdfs:comment "SARS-CoV2 nsp12 protein binding to human SLU7, as evidented by an affinity-purification mass spectrometry experiment" ; rdfs:subClassOf obo:CIDO_0000057 . obo:CIDO_0000187 a rdfs:Class ; rdfs:label "SARS-CoV-2 S binding to human ACE2"@en ; rdfs:subClassOf obo:CIDO_0000138 , obo:CIDO_0000349 . obo:CIDO_0000224 a rdf:Property ; rdfs:label "process up-regulates agent"@en ; rdfs:range ; rdfs:subPropertyOf obo:CIDO_0000223 . obo:PR_Q8N5S9 a rdfs:Class ; rdfs:label "calcium/calmodulin-dependent protein kinase kinase 1 (human)" ; rdfs:comment "A calcium/calmodulin-dependent protein kinase kinase 1 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000004994 , obo:PR_000029067 . obo:GO_0048585 a rdfs:Class ; rdfs:label "negative regulation of response to stimulus" ; rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of a response to a stimulus. Response to stimulus is a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus." ; rdfs:subClassOf obo:GO_0048519 , obo:GO_0048583 . obo:CIDO_0000080 a rdfs:Class ; rdfs:label "chemical role modulating host immune response to coronaviral infection"@en ; rdfs:comment "A role of a chemical effective in modulating host response to coronaviral infection" ; rdfs:subClassOf obo:CIDO_0000071 . obo:CIDO_0001081 a rdfs:Class ; rdfs:label "AA variant in SARS-CoV-2 nsp10 protein"@en ; rdfs:comment "An AA variant in SARS-CoV-2 nsp10 protein. Equivalent to an AA variant in SARS-CoV-2 rep 1ab with an AA position of 4231 - 4369." ; rdfs:subClassOf obo:CIDO_0000714 . obo:CIDO_0000578 a rdfs:Class ; rdfs:label "FENYIKWPWWVWLII" ; rdfs:comment "A coronavirus epitope that is part of some S protein from HCoV NL63 composed of the following amino acids FENYIKWPWWVWLII" ; rdfs:subClassOf obo:CIDO_0000449 . obo:PR_Q6PKG0 a rdfs:Class ; rdfs:label "La-related protein 1 (human)" ; rdfs:comment "A La-related protein 1 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000009668 , obo:PR_000029067 . obo:CIDO_0000109 a rdfs:Class ; rdfs:label "interruption to MERS-CoV replication in host cell"@en ; rdfs:comment "A process that interrupts MERS-CoV virus entry to host cell" ; rdfs:subClassOf obo:CIDO_0000103 . obo:PR_000015739 a rdfs:Class ; rdfs:label "serine/threonine-protein kinase 10" ; rdfs:comment "A protein that is a translation product of the human STK10 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:NCBITaxon_293319 a rdfs:Class ; rdfs:label "SARS coronavirus PC4-127" ; rdfs:subClassOf obo:NCBITaxon_694009 . obo:CHEBI_82655 a rdfs:Class ; rdfs:label "animal growth promotant" ; rdfs:comment "Substances that are administered to farmed animals to improve productivity by promoting weight gain, increasing muscle mass, limiting fat deposition, reducing feed consumption, and reducing waste production." ; rdfs:subClassOf obo:CHEBI_33286 . obo:CIDO_0000823 a rdfs:Class ; rdfs:label "SARS-CoV2 nsp13 protein binding to human AKAP9" ; rdfs:comment "SARS-CoV2 nsp13 protein binding to human AKAP9, as evidented by an affinity-purification mass spectrometry experiment" ; rdfs:subClassOf obo:CIDO_0000058 . obo:GO_0005261 a rdfs:Class ; rdfs:label "cation channel activity" ; rdfs:comment "Enables the energy-independent passage of cations across a lipid bilayer down a concentration gradient." ; rdfs:subClassOf obo:GO_0005216 , obo:GO_0022890 . obo:CHEBI_26650 a rdfs:Class ; rdfs:label "serine family amino acid" ; rdfs:comment "An L-alpha-amino acid which is biosynthesised from 3-phosphoglycerate (i.e. serine, glycine, cysteine and homocysteine). A closed class." ; rdfs:subClassOf obo:CHEBI_15705 , obo:CHEBI_83813 . obo:CIDO_0000068 a rdfs:Class ; rdfs:label "chemical role against viral replication"@en ; rdfs:subClassOf obo:CIDO_0000066 . obo:CHEBI_59876 a rdfs:Class ; rdfs:label "N-acyl-D-alpha-amino acid anion" ; rdfs:comment "The conjugate base of an N-acyl-D-alpha-amino acid arising from deprotonation of the C-1 carboxy group." ; rdfs:subClassOf obo:CHEBI_29067 . obo:VO_0005150 a rdfs:Class ; rdfs:label "rMV-S + rMV-N vaccine" ; rdfs:comment "A SARS DNA vaccine made up of arecombinat vector vaccine made from recombinant measles virus expressing S protein and recombinant measles virus expressing N protein." ; rdfs:subClassOf obo:VO_0012183 . obo:NCBITaxon_2042562 a rdfs:Class ; rdfs:label "Coronavirus PREDICT CoV-37" ; rdfs:subClassOf obo:NCBITaxon_366617 . obo:CHEBI_35224 a rdfs:Class ; rdfs:label "effector" ; rdfs:comment "A small molecule which increases (activator) or decreases (inhibitor) the activity of an (allosteric) enzyme by binding to the enzyme at the regulatory site (which is different from the substrate-binding catalytic site)." ; rdfs:subClassOf obo:CHEBI_52206 . obo:PR_000010335 a rdfs:Class ; rdfs:label "hepatocyte growth factor receptor" ; rdfs:comment "An HGF/MSP receptor type tyrosine-protein kinase that is a translation product of the human MET gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000001816 . obo:PR_P0DTC9-1 a rdfs:Class ; rdfs:label "nucleoprotein (SARS-CoV-2)" ; rdfs:comment "An N gene translation product (SARS-CoV-2) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P0DTC9-1." ; rdfs:subClassOf obo:PR_000050387 . a rdfs:Class ; rdfs:label "Ovarian Function Alteration [PE]" ; rdfs:subClassOf . obo:CIDO_0020157 a rdfs:Class ; rdfs:label "Gnomegen COVID-19 RT-Digital PCR Detection Kit" ; rdfs:seeAlso ; rdfs:subClassOf obo:CIDO_0000454 . obo:NCBITaxon_1679873 a rdfs:Class ; rdfs:label "Coronavirus Hare_CoV/La06_377/Lep_gra/ESP/2006" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:NCBITaxon_240553 a rdfs:Class ; rdfs:label "SARS coronavirus TWY" ; rdfs:subClassOf obo:NCBITaxon_694009 . obo:PR_000000008 a rdfs:Class ; rdfs:label "TGF-beta-like cystine-knot cytokine" ; rdfs:comment "A protein with a core domain composition consisting of a signal peptide, a variable propeptide region and a Transforming growth factor beta like domain (Pfam:PF00019), which is a cystine-knot domain containing four conserved beta strands, S1-S4, which form two antiparallel beta sheets (SI-S2 and S3-S4) interconnected by three disulfide bridges in a knot-like topology. Cystines [II-V] and [III-VI] form a ring through which the remaining disulfide bond (Cys[I-IV]) penetrates. Insertion of different variable regions into this common motif has given rise to various subclasses of the growth factor cystine-knot domain." ; rdfs:subClassOf obo:PR_000000001 . obo:PR_Q13627 a rdfs:Class ; rdfs:label "dual specificity tyrosine-phosphorylation-regulated kinase 1A (human)" ; rdfs:comment "A dual specificity tyrosine-phosphorylation-regulated kinase 1A that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000006781 , obo:PR_000029067 . obo:NCBITaxon_425242 a rdfs:Class ; rdfs:label "Bovine coronaviurus KV0501" ; rdfs:subClassOf obo:NCBITaxon_696098 . obo:DOID_0080281 a rdfs:Class ; rdfs:label "schizophrenia 19"@en ; rdfs:comment "A schizophrenia that has_material_basis_in heterozygous mutation in the RBM12 gene on chromosome 20q11." ; rdfs:subClassOf obo:DOID_5419 . a rdfs:Class ; rdfs:label "Decreased Cellular Migration [PE]" ; rdfs:subClassOf . obo:CIDO_0000196 a rdfs:Class ; rdfs:label "SARS-CoV-2 assembly inside cell"@en ; rdfs:subClassOf obo:CIDO_0000197 . obo:GO_0036376 a rdfs:Class ; rdfs:label "sodium ion export across plasma membrane" ; rdfs:comment "The directed movement of sodium ions from inside of a cell, across the plasma membrane and into the extracellular region." ; rdfs:subClassOf obo:GO_0035725 , obo:GO_0140115 . obo:CHEBI_189648 a rdfs:Class ; rdfs:label "PB28" ; rdfs:comment "A member of the class of tetralins that is tetralin that is substituted by 3-(4-cyclohexylpiperazin-1-yl)propyl and methoxy groups at positions 1 and 5, respectively. It is a sigma 2 (sigma2) receptor agonist (Ki = 0.68 nM) and exhibits antineoplastic and anti SARS-CoV-2 activities." ; rdfs:subClassOf obo:CHEBI_26144 , obo:CHEBI_35618 , obo:CHEBI_36786 . obo:CIDO_0000394 a rdf:Property ; rdfs:label "chemical modulates protein"@en ; rdfs:comment "An object property that represents a relation between a chemical entity and a protein where the chemical entity can target the protein as a modulator. Note that the chemical entity is usually an active compound of a corresponding drug." ; rdfs:range ; rdfs:subPropertyOf obo:CIDO_0000118 . obo:CIDO_0000978 a rdfs:Class ; rdfs:label "SARS-CoV2 orf3a protein binding to human VPS11" ; rdfs:comment "SARS-CoV2 orf3a protein binding to human VPS11, as evidented by an affinity-purification mass spectrometry experiment" ; rdfs:subClassOf obo:CIDO_0000584 . obo:GO_0051270 a rdfs:Class ; rdfs:label "regulation of cellular component movement" ; rdfs:comment "Any process that modulates the frequency, rate or extent of the movement of a cellular component." ; rdfs:subClassOf obo:GO_0032879 , obo:GO_0050794 . obo:CIDO_0001101 a rdfs:Class ; rdfs:label "SARS-CoV2 orf8 protein binding to human POGLUT3"@en ; rdfs:comment "SARS-CoV2 orf8 protein binding to human POGLUT3, as evidented by an affinity-purification mass spectrometry experiment" ; rdfs:subClassOf obo:CIDO_0000051 . a rdfs:Class ; rdfs:label "Vaginitis [Disease/Finding]" ; rdfs:subClassOf . obo:CIDO_0000318 a rdfs:Class ; rdfs:label "IGINITRFQTLLALH"@en ; rdfs:subClassOf obo:CIDO_0000314 . a rdfs:Class ; rdfs:label "Hydrocarbons, Chlorinated [Chemical/Ingredient]" ; rdfs:subClassOf . obo:CHEBI_25698 a rdfs:Class ; rdfs:label "ether" ; rdfs:comment "An organooxygen compound with formula ROR, where R is not hydrogen." ; rdfs:subClassOf obo:CHEBI_36963 . obo:GO_0065009 a rdfs:Class ; rdfs:label "regulation of molecular function" ; rdfs:comment "Any process that modulates the frequency, rate or extent of a molecular function, an elemental biological activity occurring at the molecular level, such as catalysis or binding." ; rdfs:subClassOf obo:GO_0065007 . obo:CIDO_0000848 a rdfs:Class ; rdfs:label "SARS-CoV2 nsp13 protein binding to human MIPOL1" ; rdfs:comment "SARS-CoV2 nsp13 protein binding to human MIPOL1, as evidented by an affinity-purification mass spectrometry experiment" ; rdfs:subClassOf obo:CIDO_0000058 . obo:NCBITaxon_89399 a rdfs:Class ; rdfs:label "Rhinolophus sinicus" ; rdfs:subClassOf obo:NCBITaxon_49442 . obo:GO_1901215 a rdfs:Class ; rdfs:label "negative regulation of neuron death" ; rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of neuron death." ; rdfs:subClassOf obo:GO_0060548 , obo:GO_1901214 . obo:GO_0051606 a rdfs:Class ; rdfs:label "detection of stimulus" ; rdfs:comment "The series of events in which a stimulus is received by a cell or organism and converted into a molecular signal." ; rdfs:subClassOf obo:GO_0050896 . obo:NCBITaxon_864597 a rdfs:Class ; rdfs:label "Bat coronavirus BM48-32/BGR/2008" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:PR_000050280 a rdfs:Class ; rdfs:label "non-structural protein 11 (SARS-CoV-2)" ; rdfs:comment "An ORF1a proteolytic cleavage product (SARS-CoV-2) that is the C-terminal portion produced by the enzymatic action of 3CL-PRO proteinase (nsp5) when it cleaves the precursor replicase polyprotein 1a (SARS-CoV-2) between residues 4392-4393. UniProtKB:P0DTC1, 4393-4405." ; rdfs:subClassOf obo:PR_000050282 . obo:PR_000004468 a rdfs:Class ; rdfs:label "V-type proton ATPase subunit S1" ; rdfs:comment "A protein that is a translation product of the human ATP6AP1 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:PR_000001911 a rdfs:Class ; rdfs:label "poliovirus receptor-related protein" ; rdfs:comment "A protein with core architecture consisting of an Immunoglobulin V-set domain (Pfam:PF07686), followed by a CD80-like C2-set immunoglobulin domain (Pfam:PF08205) and an Immunoglobulin domain (Pfam:PF00047)." ; rdfs:subClassOf obo:PR_000000001 . a rdfs:Class ; rdfs:label "Psoriasis [Disease/Finding]" ; rdfs:subClassOf . obo:CIDO_0000896 a rdfs:Class ; rdfs:label "SARS-CoV2 nsp7 protein binding to human DCAKD" ; rdfs:comment "SARS-CoV2 nsp7 protein binding to human DCAKD, as evidented by an affinity-purification mass spectrometry experiment" ; rdfs:subClassOf obo:CIDO_0000049 . obo:GO_0022857 a rdfs:Class ; rdfs:label "transmembrane transporter activity" ; rdfs:comment "Enables the transfer of a substance, usually a specific substance or a group of related substances, from one side of a membrane to the other." ; rdfs:subClassOf obo:GO_0003674 . obo:OBI_2000000 a rdfs:Class ; rdfs:label "uterine cervix specimen" ; rdfs:comment "A specimen that is derived from some uterine cervix " ; rdfs:subClassOf obo:OBI_0001479 . obo:CIDO_0020127 a rdfs:Class ; rdfs:label "EliA SARS-CoV-2-Sp1 IgG Test" ; rdfs:seeAlso ; rdfs:subClassOf obo:CIDO_0000454 . obo:NCBITaxon_2499399 a rdfs:Class ; rdfs:label "Cornidovirineae" ; rdfs:subClassOf obo:NCBITaxon_76804 . obo:NCBITaxon_10090 a rdfs:Class ; rdfs:label "Mus musculus" ; rdfs:subClassOf obo:NCBITaxon_39107 . obo:CHEBI_58315 a rdfs:Class ; rdfs:label "L-tyrosine zwitterion" ; rdfs:comment "An amino acid zwitterion arising from transfer of a proton from the carboxy to the amino group of L-tyrosine; major species at pH 7.3." ; rdfs:subClassOf obo:CHEBI_35238 . obo:VO_0001320 a rdfs:Class ; rdfs:label "AS03 vaccine adjuvant" ; rdfs:comment "AS03 is an emusion vaccine adjuvant that contains α-tocopherol and squalene, two biodegradable polyprenyls, in an oil-in-water emulsion." ; rdfs:subClassOf obo:VO_0001355 . obo:CIDO_0000019 a rdfs:Class ; rdfs:label "COVID-19 RT-PCR assay"@en ; rdfs:subClassOf obo:CIDO_0000259 . obo:CIDO_0001032 a rdfs:Class ; rdfs:label "ATYR1923" ; rdfs:subClassOf obo:CHEBI_23367 . obo:CIDO_0000079 a rdfs:Class ; rdfs:label "chemical role against MERS-CoV entry"@en ; rdfs:subClassOf obo:CIDO_0000076 . obo:CHEBI_78295 a rdfs:Class ; rdfs:label "food component" ; rdfs:comment "A physiological role played by any substance that is distributed in foodstuffs. It includes materials derived from plants or animals, such as vitamins or minerals, as well as environmental contaminants." ; rdfs:subClassOf obo:CHEBI_52211 . a rdfs:Class ; rdfs:label "Xanthenes [Chemical/Ingredient]" ; rdfs:subClassOf . obo:PR_000005350 a rdfs:Class ; rdfs:label "centrosome-associated protein 350" ; rdfs:comment "A protein that is a translation product of the human CEP350 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:VO_0000887 a rdfs:Class ; rdfs:label "intradermal route" ; rdfs:comment "a route of administration that inject the material(such as vaccines, allergens) into the skin itself." ; rdfs:subClassOf obo:VO_0000574 . a rdfs:Class ; rdfs:label "Electrical Activity Alteration [PE]" ; rdfs:subClassOf . obo:CIDO_0000920 a rdfs:Class ; rdfs:label "SARS-CoV2 nsp7 protein binding to human SCCPDH" ; rdfs:comment "SARS-CoV2 nsp7 protein binding to human SCCPDH, as evidented by an affinity-purification mass spectrometry experiment" ; rdfs:subClassOf obo:CIDO_0000049 . obo:NCBITaxon_454953 a rdfs:Class ; rdfs:label "Feline coronavirus UU5" ; rdfs:subClassOf obo:NCBITaxon_12663 . obo:CHEBI_33707 a rdfs:Class ; rdfs:label "gamma-amino acid" ; rdfs:comment "A non-proteinogenic amino-acid in which the amino group is located on the carbon atom at the position gamma to the carboxy group." ; rdfs:subClassOf obo:CHEBI_83820 . obo:CIDO_0000488 a rdfs:Class ; rdfs:label "EEIEYVHGDALHTLR" ; rdfs:comment "A coronavirus epitope that is part of some S protein from HCoV 229E composed of the following amino acids EEIEYVHGDALHTLR" ; rdfs:subClassOf obo:CIDO_0000451 . obo:PR_000044694 a rdfs:Class ; rdfs:label "interferon alpha (human)" ; rdfs:comment "An interferon alpha that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000024938 , obo:PR_000029067 . obo:CIDO_0000859 a rdfs:Class ; rdfs:label "SARS-CoV2 nsp13 protein binding to human TLE1" ; rdfs:comment "SARS-CoV2 nsp13 protein binding to human TLE1, as evidented by an affinity-purification mass spectrometry experiment" ; rdfs:subClassOf obo:CIDO_0000058 . obo:CIDO_0020099 a rdfs:Class ; rdfs:label "LabCorp COVID-19 RT-PCR test" ; rdfs:seeAlso ; rdfs:subClassOf obo:CIDO_0000454 . a rdfs:Class ; rdfs:label "Heart Failure [Disease/Finding]" ; rdfs:subClassOf . obo:NCBITaxon_693995 a rdfs:Class ; rdfs:label "Coronavirinae" ; rdfs:subClassOf obo:NCBITaxon_11118 . obo:NCBITaxon_2591230 a rdfs:Class ; rdfs:label "Coronavirus BtSk-AlphaCoV/GX2018C" ; rdfs:subClassOf obo:NCBITaxon_2691591 . obo:OBI_0000973 a rdfs:Class ; rdfs:label "sequence data"@en ; rdfs:comment """A measurement datum that representing the primary structure of a macromolecule(it's sequence) sometimes associated with an indicator of confidence of that measurement. """ ; rdfs:subClassOf obo:IAO_0000109 . obo:CHEBI_75991 a rdfs:Class ; rdfs:label "trametinib dimethyl sulfoxide" ; rdfs:comment "An addition compound obtained by combining equimolar amounts of trametinib and dimethyl sulfoxide. Used for the treatment of patients with unresectable or metastatic melanoma with BRAF V600E or V600K mutations, and who have not received prior BRAF inhibitor treatment." ; rdfs:subClassOf obo:CHEBI_35504 . a rdfs:Class ; rdfs:label "Purines [Chemical/Ingredient]" ; rdfs:subClassOf . obo:NCBITaxon_497932 a rdfs:Class ; rdfs:label "Bat coronavirus M.das/Germany/D3.15/2007" ; rdfs:subClassOf obo:NCBITaxon_366617 . obo:CIDO_0000008 a rdfs:Class ; rdfs:label "Human coronavirus HKU1 disease process"@en ; rdfs:subClassOf obo:CIDO_0000001 . obo:PR_000050274 a rdfs:Class ; rdfs:label "3C-like proteinase nsp5 (SARS-CoV-2)" ; rdfs:comment "A rep gene proteolytic cleavage product (SARS-CoV-2) that is the central portion produced by the autocatalytic action of 3CL-PRO proteinase (nsp5) when it cleaves the precursor rep gene translation product (SARS-CoV-2) between residues 3263-3264 and 3569-3570." ; rdfs:subClassOf obo:PR_000050281 . obo:DRON_00011652 a rdfs:Class ; rdfs:label "Thiethylperazine" ; rdfs:subClassOf obo:OBI_0000047 . obo:OBI_0000932 a rdfs:Class ; rdfs:label "material separation device" ; rdfs:comment "A device with a separation function realized in a planed process" ; rdfs:subClassOf obo:OBI_0000968 . obo:PR_Q9P2E5 a rdfs:Class ; rdfs:label "chondroitin sulfate glucuronyltransferase (human)" ; rdfs:comment "A chondroitin sulfate glucuronyltransferase that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000005935 , obo:PR_000029067 . obo:PR_000011130 a rdfs:Class ; rdfs:label "serine/threonine-protein kinase Nek4" ; rdfs:comment "A protein that is a translation product of the human NEK4 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . a rdfs:Class ; rdfs:label "Secologanin Tryptamine Alkaloids [Chemical/Ingredient]" ; rdfs:subClassOf . obo:PR_000008766 a rdfs:Class ; rdfs:label "heparan-sulfate 6-O-sulfotransferase 2" ; rdfs:comment "A protein that is a translation product of the human HS6ST2 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:NCBITaxon_284672 a rdfs:Class ; rdfs:label "SARS coronavirus TJF" ; rdfs:subClassOf obo:NCBITaxon_694009 . obo:NCBITaxon_2509497 a rdfs:Class ; rdfs:label "Minunacovirus" ; rdfs:subClassOf obo:NCBITaxon_693996 . obo:VO_0005095 a rdfs:Class ; rdfs:label "Recombinant SARS-CoV-2 vaccine (Sf9 cell)"@en ; rdfs:comment "A SARS-CoV-2 protein subunit vaccine by West China Hospital" ; rdfs:subClassOf obo:VO_0005202 . obo:CHEBI_48355 a rdfs:Class ; rdfs:label "non-polar solvent" ; rdfs:subClassOf obo:CHEBI_46787 . obo:NCBITaxon_702734 a rdfs:Class ; rdfs:label "Bat coronavirus Philippines/Diliman1525G2/2008" ; rdfs:subClassOf obo:NCBITaxon_696098 . obo:CIDO_0000680 a rdfs:Class ; rdfs:label "N679K in SARS-CoV-2 S protein" ; rdfs:comment "An AA mutation or AA variant that has mutated an amino acid at position 679 into a lysine in S protein." ; rdfs:subClassOf obo:CIDO_0000592 . obo:GO_1903416 a rdfs:Class ; rdfs:label "response to glycoside" ; rdfs:comment "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glycoside stimulus." ; rdfs:subClassOf obo:GO_0010033 , obo:GO_1901700 . obo:NCBITaxon_903588 a rdfs:Class ; rdfs:label "Kenya bat coronavirus BtKY50" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:CHEBI_24318 a rdfs:Class ; rdfs:label "glutamine family amino acid" ; rdfs:comment "An L-alpha-amino acid which is L-glutamic acid or any of the essential amino acids biosynthesised from it (glutamine, proline and arginine). A closed class." ; rdfs:subClassOf obo:CHEBI_15705 , obo:CHEBI_83813 . obo:IAO_0000577 a rdfs:Class ; rdfs:label "centrally registered identifier symbol"@en ; rdfs:comment "A symbol that is part of a CRID and that is sufficient to look up a record from the CRID's registry."@en ; rdfs:subClassOf obo:IAO_0000028 . a rdfs:Class ; rdfs:label "Ovulation Alteration [PE]" ; rdfs:subClassOf . a rdfs:Class ; rdfs:label "Tonsillitis [Disease/Finding]" ; rdfs:subClassOf . obo:PR_000000719 a rdfs:Class ; rdfs:label "voltage-gated potassium channel Eag alpha subunit" ; rdfs:comment "A voltage-gated potassium channel alpha subunit with PAS domain whose activation is characterized by a nonsuperimposable Cole-Moore shift, in which the time course of activation becomes slower and more sigmoidal as the prepulse or holding potential is made more negative and, as a consequence, the currents do not superimpose when aligned by shifting along the time axis." ; rdfs:subClassOf obo:PR_000000682 . a rdfs:Class ; rdfs:label "Decreased Autonomic Nervous System Acetylcholine Activity [PE]" ; rdfs:subClassOf . a rdfs:Class ; rdfs:label "Mefloquine [Chemical/Ingredient]" ; rdfs:subClassOf . obo:CHEBI_26147 a rdfs:Class ; rdfs:label "piperidine alkaloid" ; rdfs:subClassOf obo:CHEBI_22315 , obo:CHEBI_26151 . obo:NCBITaxon_1746086 a rdfs:Class ; rdfs:label "Bat coronavirus M.nat/GER/F0BF/2014" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:GO_0050731 a rdfs:Class ; rdfs:label "positive regulation of peptidyl-tyrosine phosphorylation" ; rdfs:comment "Any process that activates or increases the frequency, rate or extent of the phosphorylation of peptidyl-tyrosine." ; rdfs:subClassOf obo:GO_0001932 , obo:GO_0001934 . obo:CIDO_0000899 a rdfs:Class ; rdfs:label "SARS-CoV2 nsp7 protein binding to human GNB1" ; rdfs:comment "SARS-CoV2 nsp7 protein binding to human GNB1, as evidented by an affinity-purification mass spectrometry experiment" ; rdfs:subClassOf obo:CIDO_0000049 . obo:NCBITaxon_511431 a rdfs:Class ; rdfs:label "SARS coronavirus BJ182-8" ; rdfs:subClassOf obo:NCBITaxon_694009 . obo:PR_000007370 a rdfs:Class ; rdfs:label "F-box/LRR-repeat protein 12" ; rdfs:comment "A protein that is a translation product of the human FBXL12 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:CHEBI_28262 a rdfs:Class ; rdfs:label "dimethyl sulfoxide" ; rdfs:comment "A 2-carbon sulfoxide in which the sulfur atom has two methyl substituents." ; rdfs:subClassOf obo:CHEBI_134179 , obo:CHEBI_22063 . obo:NCBITaxon_1283332 a rdfs:Class ; rdfs:label "Bat coronavirus Rp/Shaanxi2011" ; rdfs:subClassOf obo:NCBITaxon_694009 . obo:VO_0005084 a rdfs:Class ; rdfs:label "KCONVAC" ; rdfs:comment "A SARS-CoV-2 inactivated virus vaccine by Shenzhen Kangtai Biological Products and Beijing Minhai Biotechnology Co."@en ; rdfs:subClassOf obo:VO_0005266 . a rdfs:Class ; rdfs:label "Dibenzazepines [Chemical/Ingredient]" ; rdfs:subClassOf . obo:PR_000004369 a rdfs:Class ; rdfs:label "asialoglycoprotein receptor 1" ; rdfs:comment "A C-type asialoglycoprotein receptor that is a translation product of the human ASGR1 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000001291 . obo:CHEBI_50926 a rdfs:Class ; rdfs:label "angiogenesis modulating agent" ; rdfs:comment "An agent that modulates the physiologic angiogenesis process. This is accomplished by endogenous angiogenic proteins and a variety of other chemicals and pharmaceutical agents." ; rdfs:subClassOf obo:CHEBI_23888 . obo:NCBITaxon_281976 a rdfs:Class ; rdfs:label "SARS coronavirus GZ0401" ; rdfs:subClassOf obo:NCBITaxon_694009 . obo:CIDO_0000784 a rdfs:Class ; rdfs:label "SARS-CoV2 N protein binding to human PABPC1" ; rdfs:comment "SARS-CoV2 N protein binding to human PABPC1, as evidented by an affinity-purification mass spectrometry experiment" ; rdfs:subClassOf obo:CIDO_0000056 . obo:NCBITaxon_756648 a rdfs:Class ; rdfs:label "Bovine coronavirus cow/WDBR-9146/BRA/2003" ; rdfs:subClassOf obo:NCBITaxon_11128 . obo:PR_000010129 a rdfs:Class ; rdfs:label "mitogen-activated protein kinase kinase kinase 10" ; rdfs:comment "A protein that is a translation product of the human MAP3K10 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:CHEBI_35505 a rdfs:Class ; rdfs:label "hydrate" ; rdfs:comment "An addition compound that contains water in weak chemical combination with another compound." ; rdfs:subClassOf obo:CHEBI_35504 . obo:CIDO_0000329 a rdfs:Class ; rdfs:label "TQLNRALTGIAVEQD"@en ; rdfs:subClassOf obo:CIDO_0000314 . obo:PR_O43293 a rdfs:Class ; rdfs:label "death-associated protein kinase 3 (human)" ; rdfs:comment "A death-associated protein kinase 3 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000006278 , obo:PR_000029067 . obo:CIDO_0020216 a rdfs:Class ; rdfs:label "Novel Coronavirus (SARS-CoV-2) Fast Nucleic Acid Detection Kit (PCR-Fluorescence Probing)" ; rdfs:seeAlso ; rdfs:subClassOf obo:CIDO_0000454 . obo:NCBITaxon_1699345 a rdfs:Class ; rdfs:label "Myotis Bat Alphacoronavirus strain YNXY_54C" ; rdfs:subClassOf obo:NCBITaxon_366617 . obo:CIDO_0000888 a rdfs:Class ; rdfs:label "SARS-CoV2 nsp6 protein binding to human ATP5MG" ; rdfs:comment "SARS-CoV2 nsp6 protein binding to human ATP5MG, as evidented by an affinity-purification mass spectrometry experiment" ; rdfs:subClassOf obo:CIDO_0000048 . obo:CIDO_0000665 a rdfs:Class ; rdfs:label "D950N in SARS-CoV-2 S protein" ; rdfs:comment "An AA mutation or AA variant that has mutated an amino acid at position 950 into a aspargine in S protein." ; rdfs:subClassOf obo:CIDO_0000595 . obo:VO_0005177 a rdfs:Class ; rdfs:label "gorilla adenovirus vector"@en ; rdfs:subClassOf obo:VO_0000136 . obo:UBERON_0002409 a rdfs:Class ; rdfs:label "pericardial fluid" ; rdfs:comment "Transudate contained in the pericardial cavity.[FMA]" ; rdfs:subClassOf obo:UBERON_0006314 . obo:CIDO_0020321 a rdfs:Class ; rdfs:label "VIDAS SARS-CoV-2 IgG" ; rdfs:seeAlso ; rdfs:subClassOf obo:CIDO_0000454 . obo:OGG_3043740576 a rdfs:Class ; rdfs:label "ORF10 of severe acute respiratory syndrome coronavirus 2" ; rdfs:subClassOf obo:OGG_2002697049 . obo:CHEBI_35406 a rdfs:Class ; rdfs:label "oxoanion" ; rdfs:comment "An oxoanion is an anion derived from an oxoacid by loss of hydron(s) bound to oxygen." ; rdfs:subClassOf obo:CHEBI_25741 , obo:CHEBI_33273 . obo:PR_000005942 a rdfs:Class ; rdfs:label "kappa-casein" ; rdfs:comment "A protein that is a translation product of the human CSN3 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:NCBITaxon_931914 a rdfs:Class ; rdfs:label "Alphacoronavirus Eptesicus fuscus/Appalachian Ridge/P1-265225/IT/USA/2009" ; rdfs:subClassOf obo:NCBITaxon_366617 . obo:DRON_00750811 a rdfs:Class ; rdfs:label "dalbavancin" ; rdfs:subClassOf obo:OBI_0000047 . obo:CHEBI_47868 a rdfs:Class ; rdfs:label "photosensitizing agent" ; rdfs:comment "A chemical compound that can be excited by light of a specific wavelength and subsequently transfer energy to a chosen reactant. This is commonly molecular oxygen within a cancer tissue, which is converted to (highly rective) singlet state oxygen. This rapidly reacts with any nearby biomolecules, ultimately killing the cancer cells." ; rdfs:subClassOf obo:CHEBI_23888 . obo:HP_0000822 a rdfs:Class ; rdfs:label "Hypertension" ; rdfs:comment "The presence of chronic increased pressure in the systemic arterial system." ; rdfs:subClassOf obo:HP_0030972 . obo:CIDO_0000510 a rdfs:Class ; rdfs:label "VMNNIVLFLTWLLSM" ; rdfs:comment "A coronavirus epitope that is part of some S protein from HCoV NL63 composed of the following amino acids VMNNIVLFLTWLLSM" ; rdfs:subClassOf obo:CIDO_0000449 . a rdfs:Class ; rdfs:label "Ocular Smooth Muscle Activity Alteration [PE]" ; rdfs:subClassOf . a rdfs:Class ; rdfs:label "Glycoconjugates [Chemical/Ingredient]" ; rdfs:subClassOf . obo:PR_000002082 a rdfs:Class ; rdfs:label "receptor tyrosine-protein kinase erbB-2" ; rdfs:comment "An EGF receptor type tyrosine-protein kinase that is a translation product of the human ERBB2 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000001812 . obo:CIDO_0000837 a rdfs:Class ; rdfs:label "SARS-CoV2 nsp13 protein binding to human FYCO1" ; rdfs:comment "SARS-CoV2 nsp13 protein binding to human FYCO1, as evidented by an affinity-purification mass spectrometry experiment" ; rdfs:subClassOf obo:CIDO_0000058 . obo:VO_0005394 a rdfs:Class ; rdfs:label "ChAdV68-S"@en ; rdfs:comment "A synthetic modified vaccinia Ankara (MVA)-based SARS-CoV-2 vaccine" ; rdfs:subClassOf obo:VO_0005199 . obo:NCBITaxon_1284373 a rdfs:Class ; rdfs:label "Bat coronavirus BtCoV/8-724/Pip_pyg/ROU/2009" ; rdfs:subClassOf obo:NCBITaxon_696098 . obo:PR_Q8NCA5 a rdfs:Class ; rdfs:label "protein FAM98A (human)" ; rdfs:comment "A protein FAM98A that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000029067 , obo:PR_000030314 . obo:CHEBI_36823 a rdfs:Class ; rdfs:label "pseudohalo group" ; rdfs:subClassOf obo:CHEBI_24433 . obo:CHEBI_67013 a rdfs:Class ; rdfs:label "methyl-branched fatty acid anion" ; rdfs:comment "Any branched-chain fatty acid anion containing methyl branches only." ; rdfs:subClassOf obo:CHEBI_58955 . obo:CHEBI_47017 a rdfs:Class ; rdfs:label "tetrahydrofuranol" ; rdfs:subClassOf obo:CHEBI_26912 . obo:PR_P08637 a rdfs:Class ; rdfs:label "low affinity immunoglobulin gamma Fc region receptor III-A (human)" ; rdfs:comment "A low affinity immunoglobulin gamma Fc region receptor III-A that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000001484 , obo:PR_000029067 . obo:PR_000005005 a rdfs:Class ; rdfs:label "calnexin" ; rdfs:comment "A protein that is a translation product of the human CANX gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:CHEBI_125204 a rdfs:Class ; rdfs:label "4-guanidinobenzoic acid" ; rdfs:comment "Benzoic acid substituted at the para position by a guanidino group." ; rdfs:subClassOf obo:CHEBI_22723 , obo:CHEBI_24436 . obo:CHEBI_33674 a rdfs:Class ; rdfs:label "s-block molecular entity" ; rdfs:comment "An s-block molecular entity is a molecular entity containing one or more atoms of an s-block element." ; rdfs:subClassOf obo:CHEBI_33579 . obo:GO_0033555 a rdfs:Class ; rdfs:label "multicellular organismal response to stress" ; rdfs:comment "Any process that results in a change in state or activity of a multicellular organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating the organism is under stress. The stress is usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation)." ; rdfs:subClassOf obo:GO_0006950 , obo:GO_0032501 . obo:NCBITaxon_2042567 a rdfs:Class ; rdfs:label "Coronavirus PREDICT CoV-41" ; rdfs:subClassOf obo:NCBITaxon_696098 . obo:PR_Q9Y2H1 a rdfs:Class ; rdfs:label "serine/threonine-protein kinase 38-like (human)" ; rdfs:comment "A serine/threonine-protein kinase 38-like that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000015755 , obo:PR_000029067 . obo:CHEBI_26513 a rdfs:Class ; rdfs:label "quinolines" ; rdfs:comment "A class of aromatic heterocyclic compounds each of which contains a benzene ring ortho fused to carbons 2 and 3 of a pyridine ring." ; rdfs:subClassOf obo:CHEBI_27171 , obo:CHEBI_33659 , obo:CHEBI_38101 . obo:GO_0008152 a rdfs:Class ; rdfs:label "metabolic process" ; rdfs:comment "The chemical reactions and pathways, including anabolism and catabolism, by which living organisms transform chemical substances. Metabolic processes typically transform small molecules, but also include macromolecular processes such as DNA repair and replication, and protein synthesis and degradation." ; rdfs:subClassOf obo:GO_0008150 . obo:OBCS_0000218 a rdfs:Class ; rdfs:label "derived data from statistical analysis"@en ; rdfs:comment "A data item that is derived from a statistical data analysis." ; rdfs:subClassOf obo:IAO_0000027 , obo:OBCS_0000233 . a rdfs:Class ; rdfs:label "Increased T Lymphocyte Destruction [PE]" ; rdfs:subClassOf . obo:NCBITaxon_384337 a rdfs:Class ; rdfs:label "Human coronavirus NO/0003/05" ; rdfs:subClassOf obo:NCBITaxon_384335 . obo:CHEBI_137113 a rdfs:Class ; rdfs:label "JQ1" ; rdfs:comment "A member of the class of thienotriazolodiazepines that is the tert-butyl ester of [(6S)-4-(4-chlorophenyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-6-yl]acetic acid. An inhibitor of bromodomain-containing protein 4 that exhibits anti-cancer and cardioprotective properties." ; rdfs:subClassOf obo:CHEBI_140402 , obo:CHEBI_33308 , obo:CHEBI_36683 , obo:CHEBI_84232 . obo:GO_0051048 a rdfs:Class ; rdfs:label "negative regulation of secretion" ; rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of the controlled release of a substance from a cell or a tissue." ; rdfs:subClassOf obo:GO_0051046 , obo:GO_0051051 . obo:CHEBI_90782 a rdfs:Class ; rdfs:label "C-terminal proteinogenic amino-acid residue(1-)" ; rdfs:comment "An alpha-amino-acid residue anion obtained by deprotonation of the carboxy group of any C-terminal proteinogenic amino acid." ; rdfs:subClassOf obo:CHEBI_143819 , obo:CHEBI_35416 . obo:CHEBI_52395 a rdfs:Class ; rdfs:label "oxyketone" ; rdfs:comment "A compound with the general formula R2C=O (R=/=H) where one or more of the R groups contains an oxy (-O-) group." ; rdfs:subClassOf obo:CHEBI_17087 . obo:NCBITaxon_1288701 a rdfs:Class ; rdfs:label "Bat coronavirus POA/2012/G01" ; rdfs:subClassOf obo:NCBITaxon_366617 . obo:DOID_252 a rdfs:Class ; rdfs:label "alcoholic psychosis" ; rdfs:comment "An alcohol-induced mental disorder involving prominent hallucinations and delusions occurring during or shortly after acute alcohol intoxication or withdrawal." ; rdfs:subClassOf obo:DOID_251 . obo:NCBITaxon_2026237 a rdfs:Class ; rdfs:label "Porcine enteric alphacoronavirus GDS04" ; rdfs:subClassOf obo:NCBITaxon_693998 . obo:CHEBI_26082 a rdfs:Class ; rdfs:label "phosphorus molecular entity" ; rdfs:subClassOf obo:CHEBI_33302 . obo:VO_0005251 a rdfs:Class ; rdfs:label "COVID-19 VLP vaccine by the Scientific and Technological Research Council of Turkey"@en ; rdfs:comment "A COVID-19 virus-like particle vaccine developed by the Scientific and Technological Research Council of Turkey" ; rdfs:subClassOf obo:VO_0005205 . obo:NCBITaxon_1717205 a rdfs:Class ; rdfs:label "Coronavirus PREDICT_CoV-50" ; rdfs:subClassOf obo:NCBITaxon_2664420 . a rdfs:Class ; rdfs:label "Cinchona Alkaloids [Chemical/Ingredient]" ; rdfs:subClassOf . obo:CIDO_0000720 a rdfs:Class ; rdfs:label "H1101Y in SARS-CoV-2 S protein"@en ; rdfs:comment "An AA mutation or AA variant that has mutated an amino acid at position 1101 into a tyrosine in S protein." ; rdfs:subClassOf obo:CIDO_0001163 . obo:OAE_0000027 a rdfs:Class ; rdfs:label "musculoskeletal or connective tissue AE" ; rdfs:comment "an adverse event that has an outcome of abnormal sign in a musculoskeletal or connective tissue." ; rdfs:subClassOf obo:OAE_0000001 . obo:GO_0007417 a rdfs:Class ; rdfs:label "central nervous system development" ; rdfs:comment "The process whose specific outcome is the progression of the central nervous system over time, from its formation to the mature structure. The central nervous system is the core nervous system that serves an integrating and coordinating function. In vertebrates it consists of the brain and spinal cord. In those invertebrates with a central nervous system it typically consists of a brain, cerebral ganglia and a nerve cord." ; rdfs:subClassOf obo:GO_0048856 . obo:CHEBI_7497 a rdfs:Class ; rdfs:label "nelfinavir mesylate" ; rdfs:comment "A methanesulfonate (mesylate) salt prepared from equimolar amounts of nelfinavir and methanesulfonic acid. It is used for treatment of HIV and also exhibits some anticancer properties." ; rdfs:subClassOf obo:CHEBI_38037 . obo:CHEBI_48278 a rdfs:Class ; rdfs:label "serotonergic drug" ; rdfs:subClassOf obo:CHEBI_35942 . obo:OBI_0002519 a rdfs:Class ; rdfs:label "skeletal muscle tissue specimen" ; rdfs:comment "A specimen that is derived from skeletal muscle." ; rdfs:subClassOf obo:OBI_0001479 . obo:GO_0071396 a rdfs:Class ; rdfs:label "cellular response to lipid" ; rdfs:comment "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lipid stimulus." ; rdfs:subClassOf obo:GO_0033993 , obo:GO_0071310 . obo:CHEBI_140326 a rdfs:Class ; rdfs:label "tertiary carboxamide" ; rdfs:comment "A carboxamide resulting from the formal condensation of a carboxylic acid with a secondary amine; formula RC(=O)NHR(1)R(2)." ; rdfs:subClassOf obo:CHEBI_37622 . obo:DOID_1229 a rdfs:Class ; rdfs:label "paranoid schizophrenia" ; rdfs:comment "A schizophrenia characterized by delusions or auditory hallucinations of persecution or being plotted against without thought disorder, disorganized behavior, or affective flattening." ; rdfs:subClassOf obo:DOID_5419 . a rdfs:Class ; rdfs:label "Strongyloidiasis [Disease/Finding]" ; rdfs:subClassOf . obo:OGG_3000003440 a rdfs:Class ; rdfs:label "IFNA2" ; rdfs:comment "Other designations: IFN-alpha-2|alpha-2a interferon|interferon alpha 2a|interferon alpha 2b|interferon alpha A|interferon alpha-2|leIF A" ; rdfs:subClassOf obo:OGG_2060009606 . obo:PR_Q9BQ95 a rdfs:Class ; rdfs:label "evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial (human)" ; rdfs:comment "An evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000006884 , obo:PR_000029067 . obo:NCBITaxon_931903 a rdfs:Class ; rdfs:label "Alphacoronavirus Eptesicus fuscus/Appalachian Ridge/P1-C368/IT/USA/2009" ; rdfs:subClassOf obo:NCBITaxon_366617 . obo:GO_0071715 a rdfs:Class ; rdfs:label "icosanoid transport" ; rdfs:comment "The directed movement of icosanoids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Icosanoids are unsaturated C20 fatty acids and skeletally related compounds." ; rdfs:subClassOf obo:GO_0046942 . a rdfs:Class ; rdfs:label "Scleroderma, Systemic [Disease/Finding]" ; rdfs:subClassOf , . obo:CHEBI_30103 a rdfs:Class ; rdfs:label "diazenide" ; rdfs:subClassOf obo:CHEBI_35106 . obo:DRON_00017043 a rdfs:Class ; rdfs:label "Astemizole" ; rdfs:subClassOf obo:OBI_0000047 . obo:VO_0005260 a rdfs:Class ; rdfs:label "COVID-19 mRNA vaccine by Shanghai East Hospital and Stemirna Therapeutics"@en ; rdfs:comment "A SARS-CoV-2 mRNA vaccine by Shanghai East Hospital and Stemirna Therapeutics" ; rdfs:subClassOf obo:VO_0005198 . obo:PR_O95573 a rdfs:Class ; rdfs:label "fatty acid CoA ligase Acsl3 (human)" ; rdfs:comment "A fatty acid CoA ligase Acsl3 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000003660 , obo:PR_000029067 . obo:PR_P19525 a rdfs:Class ; rdfs:label "interferon-induced, double-stranded RNA-activated protein kinase (human)" ; rdfs:comment "An interferon-induced, double-stranded RNA-activated protein kinase that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000006959 , obo:PR_000029067 . obo:PR_Q9UBF8 a rdfs:Class ; rdfs:label "phosphatidylinositol 4-kinase beta (human)" ; rdfs:comment "A phosphatidylinositol 4-kinase beta that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000012684 , obo:PR_000029067 . obo:VO_0005093 a rdfs:Class ; rdfs:label "QazVac" ; rdfs:comment "A SARS-CoV-2 inactivated vaccine manufactured by the Research Institute for Biological Safety Problems (Republic of Kazakhstan)" ; rdfs:subClassOf obo:VO_0005266 . obo:PR_P51956 a rdfs:Class ; rdfs:label "serine/threonine-protein kinase Nek3 (human)" ; rdfs:comment "A serine/threonine-protein kinase Nek3 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000011129 , obo:PR_000029067 . obo:PR_Q8N4C6 a rdfs:Class ; rdfs:label "ninein (human)" ; rdfs:comment "A ninein that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000011212 , obo:PR_000029067 . obo:CHEBI_16000 a rdfs:Class ; rdfs:label "ethanolamine" ; rdfs:comment "A member of the class of ethanolamines that is ethane with an amino substituent at C-1 and a hydroxy substituent at C-2, making it both a primary amine and a primary alcohol." ; rdfs:subClassOf obo:CHEBI_15734 , obo:CHEBI_23981 , obo:CHEBI_32877 . obo:NCBITaxon_983924 a rdfs:Class ; rdfs:label "Eidolon bat coronavirus/Kenya/KY24/2006" ; rdfs:subClassOf obo:NCBITaxon_696098 . obo:CIDO_0000398 a rdfs:Class ; rdfs:label "SARS-CoV-2 B.1.135.2 virus"@en ; rdfs:subClassOf obo:CIDO_0000406 . obo:CHEBI_5812 a rdfs:Class ; rdfs:label "Hydroxyprogesterone caproate" ; rdfs:subClassOf obo:CHEBI_36699 . obo:PR_000008923 a rdfs:Class ; rdfs:label "interferon alpha/beta receptor 2" ; rdfs:comment "A protein that is a translation product of the human IFNAR2 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:DRON_00000908 a rdfs:Class ; rdfs:label "loperamide tablet"@en ; rdfs:subClassOf obo:DRON_00000022 . obo:VO_0005334 a rdfs:Class ; rdfs:label "SII Bivalent"@en ; rdfs:comment "A SARS-CoV-2 bivalent protein subunit vaccine by Novavax containing antigen for both the ancestral strain and B.1.351 (Beta) variant." ; rdfs:subClassOf obo:VO_0005202 . obo:PR_000001868 a rdfs:Class ; rdfs:label "interleukin-6 receptor subunit beta" ; rdfs:comment "A protein that is a translation product of the human IL6ST gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:OBI_0000859 a rdfs:Class ; rdfs:label "cytoplasmic RNA extraction" ; rdfs:comment "A RNA extraction process in which the desired output material is RNA in the cytoplasm." ; rdfs:subClassOf obo:OBI_0666666 . obo:CIDO_0000617 a rdfs:Class ; rdfs:label "AA variant in SARS-CoV-2 NS8 protein"@en ; rdfs:subClassOf obo:CIDO_0000237 . obo:VO_0005322 a rdfs:Class ; rdfs:label "AG0302-COVID19"@en ; rdfs:comment "A SARS-CoV-2 DNA vaccine developed by AnGes." ; rdfs:subClassOf obo:VO_0005203 . obo:CHEBI_46787 a rdfs:Class ; rdfs:label "solvent" ; rdfs:comment "A liquid that can dissolve other substances (solutes) without any change in their chemical composition." ; rdfs:subClassOf obo:CHEBI_33232 , obo:CHEBI_51086 . obo:GO_0007195 a rdfs:Class ; rdfs:label "adenylate cyclase-inhibiting dopamine receptor signaling pathway" ; rdfs:comment "An adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway initiated by dopamine binding to its receptor, and ending with the regulation of a downstream cellular process." ; rdfs:subClassOf obo:GO_0007193 , obo:GO_0007212 . obo:CHEBI_74213 a rdfs:Class ; rdfs:label "EC 1.17.4.1 (ribonucleoside-diphosphate reductase) inhibitor" ; rdfs:comment "An EC 1.17.* (oxidoreductase acting on CH or CH2) inhibitor that inhibits the action of ribonucleoside-diphosphate reductase (EC 1.17.4.1)." ; rdfs:subClassOf obo:CHEBI_76848 . obo:CIDO_0000420 a rdfs:Class ; rdfs:label "human SARS patient"@en ; rdfs:comment "a human patient who is infected with SARS coronavirus" ; rdfs:subClassOf obo:CIDO_0000419 . obo:NCBITaxon_231428 a rdfs:Class ; rdfs:label "Avian infectious bronchitis virus (strain Vic S)" ; rdfs:subClassOf obo:NCBITaxon_11120 . obo:NCBITaxon_2219863 a rdfs:Class ; rdfs:label "Sparrow deltacoronavirus" ; rdfs:subClassOf obo:NCBITaxon_2724161 . obo:PR_000001974 a rdfs:Class ; rdfs:label "voltage-gated calcium channel subunit alpha" ; rdfs:comment "A voltage-gated calcium channel protein that has a core architecture consisting of four similar domains (I-VI), each containing six transmembrane helices (S1-S6), with a pore loop between S5 and S6. The S4 segments contain positively charged amino acids at every third position and serve as voltage sensors. Four Ion transport protein domains (Pfam:PF00520) are present. These may be followed by an IQ calmodulin-binding motif (Pfam:PF00612)." ; rdfs:subClassOf obo:PR_000044658 . obo:CHEBI_24319 a rdfs:Class ; rdfs:label "EC 6.3.1.2 (glutamate--ammonia ligase) inhibitor" ; rdfs:comment "An EC 6.3.* (C-N bond-forming ligase) inhibitor that interferes with the action of glutamate--ammonia ligase (EC 6.3.1.2)." ; rdfs:subClassOf obo:CHEBI_76823 . obo:CHEBI_32531 a rdfs:Class ; rdfs:label "histidinium(1+)" ; rdfs:subClassOf obo:CHEBI_33719 . a rdfs:Class ; rdfs:label "RNA Virus Infections [Disease/Finding]" ; rdfs:subClassOf obo:DOID_934 . obo:OBI_0001506 a rdfs:Class ; rdfs:label "specimen with pre- or post-mortem status"@en ; rdfs:comment "A specimen that has been established to be taken from a live (pre-mortem) or dead (post-mortem) organism." ; rdfs:subClassOf obo:OBI_0100051 . obo:HP_0001369 a rdfs:Class ; rdfs:label "Arthritis" ; rdfs:comment "Inflammation of a joint." ; rdfs:subClassOf obo:HP_0011842 . obo:GO_0002016 a rdfs:Class ; rdfs:label "regulation of blood volume by renin-angiotensin" ; rdfs:comment "The process in which the renin-angiotensin system controls the rate of fluid intake and output into the blood." ; rdfs:subClassOf obo:GO_0003081 . obo:PR_000010186 a rdfs:Class ; rdfs:label "serine/threonine-protein kinase MARK1" ; rdfs:comment "A protein that is a translation product of the human MARK1 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . a rdfs:Class ; rdfs:label "Skin Diseases, Vesiculobullous [Disease/Finding]" ; rdfs:subClassOf . obo:PR_P48051 a rdfs:Class ; rdfs:label "G protein-activated inward rectifier potassium channel 2 (human)" ; rdfs:comment "A G protein-activated inward rectifier potassium channel 2 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000002003 , obo:PR_000029067 . obo:CIDO_0000239 a rdfs:Class ; rdfs:label "Q57H in SARS-CoV2 NS3 protein"@en ; rdfs:comment "An aa-changing SNP variant of G25563T that occurs in the ORF3a protein of a SARS-CoV-2 virus. It is a characteristic mutation of SARS-CoV-2 clade GH." ; rdfs:subClassOf obo:CIDO_0000616 . obo:GO_0098771 a rdfs:Class ; rdfs:label "inorganic ion homeostasis" ; rdfs:comment "Any process involved in the maintenance of an internal steady state of inorganic ions within an organism or cell." ; rdfs:subClassOf obo:GO_0050801 . obo:HP_0031674 a rdfs:Class ; rdfs:label "Antidromic atrioventricular reentrant tachycardia" ; rdfs:comment "A type of atrioventricular reentrant tachycardia (AVRT) where the accessory pathway is used for anterograde conduction and the atrioventricular node for retrograde conduction." ; rdfs:subClassOf obo:HP_0011717 . obo:OPMI_0000285 a rdfs:Class ; rdfs:label "visit temporal region"@en ; rdfs:comment "the date or time on which a visit occurs" ; rdfs:subClassOf obo:BFO_0000148 . obo:CIDO_0000639 a rdfs:Class ; rdfs:label "K1795Q in SARS-CoV-2 pp1a protein" ; rdfs:comment "An AA mutation or AA variant that has mutated an amino acid at position 1795 into a glutamine in pp1a." ; rdfs:subClassOf obo:CIDO_0001074 . obo:CHEBI_39867 a rdfs:Class ; rdfs:label "valproic acid" ; rdfs:comment "A branched-chain saturated fatty acid that comprises of a propyl substituent on a pentanoic acid stem." ; rdfs:subClassOf obo:CHEBI_35819 , obo:CHEBI_39417 . obo:NCBITaxon_389234 a rdfs:Class ; rdfs:label "Bat coronavirus (BtCoV/309/2005)" ; rdfs:subClassOf obo:NCBITaxon_389126 . obo:CHEBI_64926 a rdfs:Class ; rdfs:label "serine protease inhibitor" ; rdfs:comment "Any protease inhibitor that restricts the action of a serine protease." ; rdfs:subClassOf obo:CHEBI_37670 . obo:HP_0410042 a rdfs:Class ; rdfs:label "Abnormal liver morphology" ; rdfs:comment "Any structural anomaly of the bile-secreting organ that is important for detoxification, for fat, carbohydrate, and protein metabolism, and for glycogen storage." ; rdfs:subClassOf obo:HP_0025031 . obo:CHEBI_79388 a rdfs:Class ; rdfs:label "divalent inorganic anion" ; rdfs:comment "Any inorganic anion with a valency of two." ; rdfs:subClassOf obo:CHEBI_24834 . a rdfs:Class ; rdfs:label "Neurotransmitter Transporter Interactions [MoA]" ; rdfs:subClassOf . obo:NCBITaxon_1699334 a rdfs:Class ; rdfs:label "Myotis Bat Alphacoronavirus strain YNXY_34C" ; rdfs:subClassOf obo:NCBITaxon_366617 . a rdfs:Class ; rdfs:label "Glomerulosclerosis, Focal Segmental [Disease/Finding]" ; rdfs:subClassOf . obo:NCBITaxon_1746085 a rdfs:Class ; rdfs:label "Bat coronavirus M.nat/GER/533A/2014" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:CIDO_0000521 a rdfs:Class ; rdfs:label "IQESIKSLNNSYINL" ; rdfs:comment "A coronavirus epitope that is part of some S protein from HCoV HKU1 composed of the following amino acids IQESIKSLNNSYINL" ; rdfs:subClassOf obo:CIDO_0000450 . a rdfs:Class ; rdfs:label "Retroviridae Infections [Disease/Finding]" ; rdfs:subClassOf . a rdfs:Class ; rdfs:label "Intestinal Diseases [Disease/Finding]" ; rdfs:subClassOf . obo:PR_000029113 a rdfs:Class ; rdfs:label "glutathione S-transferase P" ; rdfs:comment "A glutathione S-transferase pi that is a translation product of the human GSTP1 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000029950 . obo:VO_0000491 a rdfs:Class ; rdfs:label "active immunization" ; rdfs:comment "Active immunization is an immunization process that entails the introduction of a foreign molecule into the body, which causes the body itself to generate adaptive immunity against the target." ; rdfs:subClassOf obo:VO_0000490 . obo:PR_P54756 a rdfs:Class ; rdfs:label "ephrin type-A receptor 5 (human)" ; rdfs:comment "An ephrin type-A receptor 5 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000007125 , obo:PR_000029067 . obo:CHEBI_32612 a rdfs:Class ; rdfs:label "isoleucinate" ; rdfs:subClassOf obo:CHEBI_33558 . obo:VO_0005244 a rdfs:Class ; rdfs:label "Soberana Plus"@en ; rdfs:comment "A SARS-CoV-2 protein subunit vaccine manufactured by Instituto Finlay de Vacunas. It is used as a booster dose for the Soberana 02 COVID-19 vaccine" ; rdfs:subClassOf obo:VO_0005269 . obo:PR_000003532 a rdfs:Class ; rdfs:label "alpha-aminoadipic semialdehyde synthase, mitochondrial" ; rdfs:comment "A protein that is a translation product of the human AASS gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:NCBITaxon_1146850 a rdfs:Class ; rdfs:label "Bat coronavirus M.daubentonii/UK/Wyt/972A" ; rdfs:subClassOf obo:NCBITaxon_366617 . obo:CHEBI_25482 a rdfs:Class ; rdfs:label "naphthoate" ; rdfs:subClassOf obo:CHEBI_35757 . obo:PR_000007124 a rdfs:Class ; rdfs:label "ephrin type-A receptor 4" ; rdfs:comment "An ephrin receptor that is a translation product of the human EPHA4 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000025845 . obo:VO_0005204 a rdfs:Class ; rdfs:label "COVID-19 live, attenuated vaccine"@en ; rdfs:subClassOf obo:VO_0004908 . a rdfs:Class ; rdfs:label "Sexually Transmitted Diseases, Viral [Disease/Finding]" ; rdfs:subClassOf . obo:NCBITaxon_1679918 a rdfs:Class ; rdfs:label "Coronavirus RCoV/RMU10_3147/Apo_fla/GER/2010" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:GO_0033993 a rdfs:Class ; rdfs:label "response to lipid" ; rdfs:comment "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lipid stimulus." ; rdfs:subClassOf obo:GO_0010033 . obo:NCBITaxon_1159905 a rdfs:Class ; rdfs:label "Porcine coronavirus HKU15" ; rdfs:subClassOf obo:NCBITaxon_1965089 . obo:NCBITaxon_2042578 a rdfs:Class ; rdfs:label "Coronavirus PREDICT CoV-54" ; rdfs:subClassOf obo:NCBITaxon_366617 . obo:CIDO_0020053 a rdfs:Class ; rdfs:label "BioCore 2019-nCoV Real Time PCR Kit" ; rdfs:seeAlso ; rdfs:subClassOf obo:CIDO_0000454 . a rdfs:Class ; rdfs:label "Selective Estrogen Receptor Modulators [MoA]" ; rdfs:subClassOf . obo:PR_000050012 a rdfs:Class ; rdfs:label "annexin A" ; rdfs:comment "A protein that is a translation product of the human ANXA1, ANXA2, ANXA3, ANXA4, ANXA5, ANXA6, ANXA7, ANXA8, ANXA8L1, ANXA9, ANXA10, ANXA11, or ANXA13 genes, or 1:1 orthologs thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:VO_0005323 a rdfs:Class ; rdfs:label "authorized COVID-19 DNA vaccine"@en ; rdfs:subClassOf obo:VO_0005203 , obo:VO_0005264 . obo:CHEBI_24432 a rdfs:Class ; rdfs:label "biological role" ; rdfs:comment "A role played by the molecular entity or part thereof within a biological context." ; rdfs:subClassOf obo:CHEBI_50906 . obo:PR_000001706 a rdfs:Class ; rdfs:label "sphingosine 1-phosphate receptor 1" ; rdfs:comment "A lysophospholipid (S1P) receptor that is a translation product of the human S1PR1 gene or a 1:1 ortholog thereof. The receptor is specifically expressed in endothelial cells, and to a lesser extent, in vascular smooth muscle cells, fibroblasts, melanocytes, and cells of epithelioid origin." ; rdfs:subClassOf obo:PR_000001673 . obo:CHEBI_87101 a rdfs:Class ; rdfs:label "triazole antifungal drug" ; rdfs:comment "Any triazole antifungal agent that has been used for the treatment of fungal infections in humans or animals." ; rdfs:subClassOf obo:CHEBI_86426 . obo:CHEBI_38222 a rdfs:Class ; rdfs:label "hydrocarbyl anion" ; rdfs:subClassOf obo:CHEBI_25696 . a rdfs:Class ; rdfs:label "Translation Alteration [PE]" ; rdfs:subClassOf . obo:OPMI_0000435 a rdfs:Class ; rdfs:label "positive COVID-19 diagnosis conclusion"@en ; rdfs:comment "The representation of a positive conclusion of a diagnostic process for the COVID-19 coronavirus disease." ; rdfs:subClassOf obo:CIDO_0000430 . obo:GO_0002209 a rdfs:Class ; rdfs:label "behavioral defense response" ; rdfs:comment "A behavioral response seeking to protect an organism from an a perceived external threat to that organism." ; rdfs:subClassOf obo:GO_0006952 , obo:GO_0007610 . obo:CIDO_0000217 a rdfs:Class ; rdfs:label "SARS-CoV-2 N protein synthesis"@en ; rdfs:subClassOf obo:CIDO_0000213 . obo:NCBITaxon_258445 a rdfs:Class ; rdfs:label "SARS coronavirus GD69" ; rdfs:subClassOf obo:NCBITaxon_694009 . obo:CHEBI_33704 a rdfs:Class ; rdfs:label "alpha-amino acid" ; rdfs:comment "An amino acid in which the amino group is located on the carbon atom at the position alpha to the carboxy group." ; rdfs:subClassOf obo:CHEBI_33709 . obo:PR_P29376 a rdfs:Class ; rdfs:label "leukocyte tyrosine kinase receptor (human)" ; rdfs:comment "A leukocyte tyrosine kinase receptor that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000009979 , obo:PR_000029067 . obo:NCBITaxon_11126 a rdfs:Class ; rdfs:label "Avian infectious bronchitis virus (strain KB8523)" ; rdfs:subClassOf obo:NCBITaxon_11120 . obo:CIDO_0000568 a rdfs:Class ; rdfs:label "QQVDRLITGRLAALN" ; rdfs:comment "A coronavirus epitope that is part of some S protein from HCoV 229E composed of the following amino acids QQVDRLITGRLAALN" ; rdfs:subClassOf obo:CIDO_0000451 . obo:CIDO_0000853 a rdfs:Class ; rdfs:label "SARS-CoV2 nsp13 protein binding to human PRKACA" ; rdfs:comment "SARS-CoV2 nsp13 protein binding to human PRKACA, as evidented by an affinity-purification mass spectrometry experiment" ; rdfs:subClassOf obo:CIDO_0000058 . obo:CHEBI_76842 a rdfs:Class ; rdfs:label "vancomycin(1+)" ; rdfs:comment "An organic cation that is the conjugate acid of vancomycin, obtained by deprotonation of the carboxy group and protonation of the two amino functions; major species at pH 7.3." ; rdfs:subClassOf obo:CHEBI_25697 . obo:HP_0002715 a rdfs:Class ; rdfs:label "Abnormality of the immune system" ; rdfs:comment "An abnormality of the immune system." ; rdfs:subClassOf obo:HP_0000118 . obo:PR_000050164 a rdfs:Class ; rdfs:label "GAF-containing cyclic nucleotide-dependent 3',5'-cyclic phosphodiesterase" ; rdfs:comment "A protein that contains two copies of a GAF domain (Pfam:PF01590 or Pfam:PF13185) followed by a 3'5'-cyclic nucleotide phosphodiesterase (Pfam:PF00233) domain." ; rdfs:subClassOf obo:PR_000000001 . obo:NCBITaxon_233872 a rdfs:Class ; rdfs:label "SARS coronavirus TWC" ; rdfs:subClassOf obo:NCBITaxon_694009 . obo:CHEBI_36834 a rdfs:Class ; rdfs:label "3-hydroxy steroid" ; rdfs:comment "Any hydroxy steroid carrying a hydroxy group at position 3." ; rdfs:subClassOf obo:CHEBI_35350 . obo:PR_P52564 a rdfs:Class ; rdfs:label "dual specificity mitogen-activated protein kinase kinase 6 (human)" ; rdfs:comment "A dual specificity mitogen-activated protein kinase kinase 6 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000003282 , obo:PR_000029067 . obo:GO_0010033 a rdfs:Class ; rdfs:label "response to organic substance" ; rdfs:comment "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an organic substance stimulus." ; rdfs:subClassOf obo:GO_0042221 . obo:OBI_0002743 a rdfs:Class ; rdfs:label "molecular label role"@en ; rdfs:comment "A reagent role inhering in a molecular entity intended to associate with some molecular target to serve as a proxy for the presence, abundance, or location of this target in a detection of molecular label assay."@en ; rdfs:subClassOf obo:OBI_0000086 . obo:NCBITaxon_627434 a rdfs:Class ; rdfs:label "Feline coronavirus UU16" ; rdfs:subClassOf obo:NCBITaxon_12663 . obo:NCBITaxon_497943 a rdfs:Class ; rdfs:label "Bat coronavirus P.pyg/Germany/D5.70/2007" ; rdfs:subClassOf obo:NCBITaxon_366617 . obo:PR_O96017 a rdfs:Class ; rdfs:label "serine/threonine-protein kinase Chk2 (human)" ; rdfs:comment "A serine/threonine-protein kinase Chk2 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000005418 , obo:PR_000029067 . obo:CIDO_0000679 a rdfs:Class ; rdfs:label "N211I in SARS-CoV-2 S protein" ; rdfs:comment "An AA mutation or AA variant that has mutated an amino acid at position 211 into a isoleucine" ; rdfs:subClassOf obo:CIDO_0000594 . obo:GO_0050877 a rdfs:Class ; rdfs:label "nervous system process" ; rdfs:comment "A organ system process carried out by any of the organs or tissues of neurological system." ; rdfs:subClassOf obo:GO_0003008 . obo:VO_0000623 a rdfs:Class ; rdfs:label "DNA vaccine role"@en ; rdfs:comment "a vaccine role that indicates the vaccine being a DNA vaccine. " ; rdfs:subClassOf obo:VO_0000615 . obo:UBERON_0001225 a rdfs:Class ; rdfs:label "cortex of kidney" ; rdfs:comment "Outer cortical portion of the kidney, between the renal capsule and the renal medulla." ; rdfs:subClassOf obo:UBERON_0000465 . obo:PR_000031145 a rdfs:Class ; rdfs:label "centrosomal protein of 112 kDa" ; rdfs:comment "A protein that is a translation product of the human CEP112 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:CHEBI_173084 a rdfs:Class ; rdfs:label "ferroptosis inhibitor" ; rdfs:comment "Any substance that inhibits the process of ferroptosis (a type of programmed cell death dependent on iron and characterized by the accumulation of lipid peroxides) in organisms." ; rdfs:subClassOf obo:CHEBI_35222 , obo:CHEBI_52206 . obo:PR_000002002 a rdfs:Class ; rdfs:label "G protein-activated inward rectifier potassium channel 1" ; rdfs:comment "A G protein-activated inward rectifier potassium channel that is a translation product of the human KCNJ3 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000001814 . obo:PR_P10415 a rdfs:Class ; rdfs:label "apoptosis regulator Bcl-2 (human)" ; rdfs:comment "An apoptosis regulator Bcl-2 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000002307 , obo:PR_000029067 . obo:CIDO_0001112 a rdfs:Class ; rdfs:label "SARS-CoV2 orf8 protein binding to human FKBP7"@en ; rdfs:comment "SARS-CoV2 orf8 protein binding to human FKBP7, as evidented by an affinity-purification mass spectrometry experiment" ; rdfs:subClassOf obo:CIDO_0000051 . obo:CHEBI_63436 a rdfs:Class ; rdfs:label "carbohydrate acid derivative" ; rdfs:comment "A carbohydrate derivative that is formally obtained from a carbohydrate acid." ; rdfs:subClassOf obo:CHEBI_63299 . obo:CHEBI_62081 a rdfs:Class ; rdfs:label "1,1-diunsubstituted alkanesulfonate" ; rdfs:comment "An alkanesulfonate in which the carbon at position 1 is attached to at least two hydrogens." ; rdfs:subClassOf obo:CHEBI_134249 , obo:CHEBI_33554 . obo:NCBITaxon_1679926 a rdfs:Class ; rdfs:label "Coronavirus Rabbit_CoV/La09_31/Ory_cun/ESP/2009" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:GO_0007204 a rdfs:Class ; rdfs:label "positive regulation of cytosolic calcium ion concentration" ; rdfs:comment "Any process that increases the concentration of calcium ions in the cytosol." ; rdfs:subClassOf obo:GO_0065008 . obo:PR_Q2PZI1 a rdfs:Class ; rdfs:label "probable C-mannosyltransferase DPY19L1 (human)" ; rdfs:comment "A protein dpy-19 1 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000006671 , obo:PR_000029067 . obo:PR_Q9H2H8 a rdfs:Class ; rdfs:label "peptidyl-prolyl cis-trans isomerase-like 3 (human)" ; rdfs:comment "A peptidyl-prolyl cis-trans isomerase-like 3 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000013085 , obo:PR_000029067 . obo:PR_Q05940 a rdfs:Class ; rdfs:label "synaptic vesicular amine transporter (human)" ; rdfs:comment "A synaptic vesicular amine transporter that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000014967 , obo:PR_000029067 . obo:HP_0032556 a rdfs:Class ; rdfs:label "Circumoral cyanosis" ; rdfs:comment "Persistent blue color of the skin that surrounds the mouth." ; rdfs:subClassOf obo:HP_0000961 . obo:OBCS_0000001 a rdfs:Class ; rdfs:label "statistical data analysis"@en ; rdfs:comment "a data transformation that has input of mulitple data and report overall trend of the data. " ; rdfs:subClassOf obo:OBI_0200000 . obo:NCBITaxon_9534 a rdfs:Class ; rdfs:label "Chlorocebus aethiops" ; rdfs:subClassOf obo:NCBITaxon_9526 . obo:OPMI_0000581 a rdfs:Class ; rdfs:label "measurement datetime"@en ; rdfs:comment "A datetime when a measurement is conducted." ; rdfs:subClassOf obo:OPMI_0000579 . obo:NCBITaxon_622715 a rdfs:Class ; rdfs:label "Bat coronavirus Hipposideros/GhanaKwam/26/2008" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:CIDO_0000509 a rdfs:Class ; rdfs:label "IFKNNTSFPTNIAVE" ; rdfs:comment "A coronavirus epitope that is part of some S protein from HCoV HKU1 composed of the following amino acids IFKNNTSFPTNIAVE" ; rdfs:subClassOf obo:CIDO_0000450 . obo:OBI_0000747 a rdfs:Class ; rdfs:label "material sample" ; rdfs:comment "A material entity that has the material sample role" ; rdfs:subClassOf obo:BFO_0000040 , obo:OBI_0100051 . obo:CHEBI_76812 a rdfs:Class ; rdfs:label "EC 2.7.11.* (protein-serine/threonine kinase) inhibitor" ; rdfs:comment "An EC 2.7.* (P-containing group transferase) inhibitor that interferes with the action of any protein-serine/threonine kinase (EC 2.7.11.*)." ; rdfs:subClassOf obo:CHEBI_37699 , obo:CHEBI_76668 . obo:CHEBI_25541 a rdfs:Class ; rdfs:label "nigerans" ; rdfs:subClassOf obo:CHEBI_37163 . obo:PR_Q9NY61 a rdfs:Class ; rdfs:label "protein AATF (human)" ; rdfs:comment "A protein AATF that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000003534 , obo:PR_000029067 . obo:CHEBI_29067 a rdfs:Class ; rdfs:label "carboxylic acid anion" ; rdfs:comment "The conjugate base formed when the carboxy group of a carboxylic acid is deprotonated." ; rdfs:subClassOf obo:CHEBI_25696 , obo:CHEBI_35406 . obo:CHEBI_32878 a rdfs:Class ; rdfs:label "alkene" ; rdfs:comment "An acyclic branched or unbranched hydrocarbon having one carbon-carbon double bond and the general formula CnH2n. Acyclic branched or unbranched hydrocarbons having more than one double bond are alkadienes, alkatrienes, etc." ; rdfs:subClassOf obo:CHEBI_33645 . obo:CIDO_0020085 a rdfs:Class ; rdfs:label "Color COVID-19 Test Unmonitored Collection Kit" ; rdfs:seeAlso ; rdfs:subClassOf obo:CIDO_0000455 . obo:PR_000003033 a rdfs:Class ; rdfs:label "leucine-rich repeat serine/threonine-protein kinase 2" ; rdfs:comment "A protein that is a translation product of the human LRRK2 gene or a 1:1 ortholog thereof. LRRK2 belongs to a gene family known as Roco. Roco genes encode for large proteins that have a characteristic GTPase domain, named Roc, plus a domain of unknown function called COR. Several Roco proteins also contain a protein kinase domain. Leucine-rich repeat serine/threonine-protein kinase 2 contains an N-terminal repeat that is unique to this protein." ; rdfs:subClassOf obo:PR_000000001 . obo:CIDO_0000983 a rdfs:Class ; rdfs:label "SARS-CoV2 orf6 protein binding to human RAE1" ; rdfs:comment "SARS-CoV2 orf6 protein binding to human RAE1, as evidented by an affinity-purification mass spectrometry experiment" ; rdfs:subClassOf obo:CIDO_0000586 . obo:OPMI_0000518 a rdfs:Class ; rdfs:label "provenance of drug record"@en ; rdfs:comment "A provenance of record that determines the provenance of a drug prescription, which delineates prescriptions written, prescriptions dispensed, medication history, patient-reported exposure, etc." ; rdfs:subClassOf obo:OPMI_0000512 . obo:CHEBI_83057 a rdfs:Class ; rdfs:label "Daphnia metabolite" ; rdfs:comment "A crustacean metabolite produced by the genus of small planktonic arthropods, Daphnia" ; rdfs:subClassOf obo:CHEBI_83039 . obo:PR_Q9BUB5 a rdfs:Class ; rdfs:label "MAP kinase-interacting serine/threonine-protein kinase 1 (human)" ; rdfs:comment "A MAP kinase-interacting serine/threonine-protein kinase 1 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000010429 , obo:PR_000029067 . obo:UBERON_0013756 a rdfs:Class ; rdfs:label "venous blood" ; rdfs:comment "A blood that is part of a vein." ; rdfs:subClassOf obo:UBERON_0000178 . obo:OBI_1110109 a rdfs:Class ; rdfs:label "target of material addition" ; rdfs:comment "A material entity into which another is being added in a material combinatino process" ; rdfs:subClassOf obo:BFO_0000040 . obo:NCBITaxon_241629 a rdfs:Class ; rdfs:label "SARS coronavirus TWC3" ; rdfs:subClassOf obo:NCBITaxon_694009 . a rdfs:Class ; rdfs:label "Amodiaquine [Chemical/Ingredient]" ; rdfs:subClassOf . obo:OAE_0000369 a rdfs:Class ; rdfs:label "injection-site pain AE" ; rdfs:comment "a pain AE that occurs in an injection site of a medical intervention" ; rdfs:subClassOf obo:OAE_0000366 , obo:OAE_0000374 . obo:PR_000008287 a rdfs:Class ; rdfs:label "glycogen synthase kinase-3 alpha" ; rdfs:comment "A glycogen synthase kinase 3 that is a translation product of the human GSK3A gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000050019 . obo:CIDO_0020150 a rdfs:Class ; rdfs:label "Genesig real-time PCR COVID-2019 assay" ; rdfs:seeAlso ; rdfs:subClassOf obo:CIDO_0000454 . a rdfs:Class ; rdfs:label "Young Child [Disease/Finding]" ; rdfs:subClassOf . obo:NCBITaxon_1146861 a rdfs:Class ; rdfs:label "Bat coronavirus M.nattereri/UK/Wyt/1018A" ; rdfs:subClassOf obo:NCBITaxon_366617 . obo:CHEBI_50491 a rdfs:Class ; rdfs:label "haloalkyl group" ; rdfs:comment "A group derived from a haloalkane by removal of a hydrogen atom." ; rdfs:subClassOf obo:CHEBI_33249 . obo:CHEBI_169666 a rdfs:Class ; rdfs:label "Desacetyl-nitazoxanide" ; rdfs:subClassOf obo:CHEBI_53443 . obo:CHEBI_77024 a rdfs:Class ; rdfs:label "EC 3.1.3.41 (4-nitrophenylphosphatase) inhibitor" ; rdfs:comment "An EC 3.1.3.* (phosphoric monoester hydrolase) inhibitor that interferes with the action of 4-nitrophenylphosphatase (EC 3.1.3.41)." ; rdfs:subClassOf obo:CHEBI_76775 . obo:NCBITaxon_2520504 a rdfs:Class ; rdfs:label "Alphacoronavirus UKRn3" ; rdfs:subClassOf obo:NCBITaxon_2724758 . obo:NCBITaxon_385685 a rdfs:Class ; rdfs:label "SARS coronavirus ES191" ; rdfs:subClassOf obo:NCBITaxon_694009 . obo:PR_Q13868 a rdfs:Class ; rdfs:label "exosome complex component RRP4 (human)" ; rdfs:comment "An exosome complex component RRP4 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000007259 , obo:PR_000029067 . obo:GO_0042069 a rdfs:Class ; rdfs:label "regulation of catecholamine metabolic process" ; rdfs:comment "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving catecholamines." ; rdfs:subClassOf obo:GO_0033238 , obo:GO_0080090 . obo:CHEBI_22729 a rdfs:Class ; rdfs:label "benzoquinones" ; rdfs:comment "Any quinone resulting from the formal oxidation of catechol, hydroquinone, or their C-substituted derivatives." ; rdfs:subClassOf obo:CHEBI_36141 . obo:CHEBI_33645 a rdfs:Class ; rdfs:label "acyclic olefin" ; rdfs:comment "Acyclic branched or unbranched hydrocarbons having one or more carbon-carbon double bond." ; rdfs:subClassOf obo:CHEBI_33641 . obo:CHEBI_76881 a rdfs:Class ; rdfs:label "EC 2.7.1.* (phosphotransferases with an alcohol group as acceptor) inhibitor" ; rdfs:comment "An EC 2.7.* (P-containing group transferase) inhibitor that interferes with the action of any phosphotransferase with an alcohol group as acceptor (EC 2.7.1.*)." ; rdfs:subClassOf obo:CHEBI_76668 . obo:CIDO_0000442 a rdfs:Class ; rdfs:label "HCoV NL63 protein"@en ; rdfs:subClassOf obo:CIDO_0000440 , obo:PR_000000001 . obo:CIDO_0020146 a rdfs:Class ; rdfs:label "Fulgent COVID-19 by RT-PCR Test" ; rdfs:seeAlso ; rdfs:subClassOf obo:CIDO_0000454 . obo:PR_000000033 a rdfs:Class ; rdfs:label "tumor necrosis factor, TNF-like" ; rdfs:comment "A protein with a core domain composition consisting of an N-terminal cytosolic domain, a type II transmembrane domain and a C-terminal TNF domain (Pfam:PF00229)." ; rdfs:subClassOf obo:PR_000000001 . obo:UBERON_0000071 a rdfs:Class ; rdfs:label "death stage" ; rdfs:comment "End of the life of an organism." ; rdfs:subClassOf obo:BFO_0000015 . obo:HP_0000961 a rdfs:Class ; rdfs:label "Cyanosis" ; rdfs:comment "Bluish discoloration of the skin and mucosa due to poor circulation or inadequate oxygenation of arterial or capillary blood." ; rdfs:subClassOf obo:HP_0000118 , obo:HP_0002795 . obo:PR_O96028 a rdfs:Class ; rdfs:label "histone-lysine N-methyltransferase NSD2 (human)" ; rdfs:comment "A histone-lysine N-methyltransferase NSD2 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000029067 , obo:PR_000030426 . obo:NCBITaxon_1429866 a rdfs:Class ; rdfs:label "Betacoronavirus Rhinolophus hipposideros/Italy/243585/2012" ; rdfs:subClassOf obo:NCBITaxon_696098 . obo:NCBITaxon_1788423 a rdfs:Class ; rdfs:label "Bat coronavirus MfusBtCoV 4040" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:GO_0050794 a rdfs:Class ; rdfs:label "regulation of cellular process" ; rdfs:comment "Any process that modulates the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level." ; rdfs:subClassOf obo:GO_0050789 . obo:CHEBI_27577 a rdfs:Class ; rdfs:label "phosphoramidate ester" ; rdfs:comment "A phosphoric ester (phosphate) that has an NR2 instead of an OH group." ; rdfs:subClassOf obo:CHEBI_17102 , obo:CHEBI_37734 . obo:PR_000005264 a rdfs:Class ; rdfs:label "cyclin-dependent kinase 6" ; rdfs:comment "A CDK2-related kinase that is a translation product of the human CDK6 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000003270 . obo:OPMI_0000446 a rdfs:Class ; rdfs:label "immune biomarker"@en ; rdfs:subClassOf obo:OPMI_0000445 . a rdfs:Class ; rdfs:label "terconazole [Chemical/Ingredient]" ; rdfs:subClassOf . obo:CL_0000000 a rdfs:Class ; rdfs:label "cell" ; rdfs:comment "A material entity of anatomical origin (part of or deriving from an organism) that has as its parts a maximally connected cell compartment surrounded by a plasma membrane." ; rdfs:subClassOf obo:BFO_0000040 . obo:NCBITaxon_230522 a rdfs:Class ; rdfs:label "SARS coronavirus Taiwan JC-2003" ; rdfs:subClassOf obo:NCBITaxon_694009 . obo:APOLLO_SV_00000489 a rdfs:Class ; rdfs:label "contact isolation control measure"@en ; rdfs:comment "A case isolation control measure that has an action specification that is realized in preventing one or more infectious organisms from having physical contact with other organisms."@en ; rdfs:subClassOf obo:APOLLO_SV_00000230 . obo:CIDO_0020304 a rdfs:Class ; rdfs:label "TaqPath COVID-19, FluA, FluB Combo Kit" ; rdfs:seeAlso ; rdfs:subClassOf obo:CIDO_0000454 . obo:CIDO_0000694 a rdfs:Class ; rdfs:label "S375F in SARS-CoV-2 S protein" ; rdfs:comment "An AA mutation or AA variant that has mutated an amino acid at position 375 into a phenylalanine in S protein." ; rdfs:subClassOf obo:CIDO_0000593 . obo:NCBITaxon_1346295 a rdfs:Class ; rdfs:label "Betacoronavirus BtCoV/KCR260/Car_per/CRC/2012" ; rdfs:subClassOf obo:NCBITaxon_696098 . obo:NCBITaxon_903574 a rdfs:Class ; rdfs:label "Kenya bat coronavirus BtKY106" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:NCBITaxon_1679879 a rdfs:Class ; rdfs:label "Coronavirus Hare_CoV/La08_60/Lep_gra/ESP/2008" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:PR_P06213 a rdfs:Class ; rdfs:label "insulin receptor (human)" ; rdfs:comment "An insulin receptor that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000009064 , obo:PR_000029067 . obo:NCBITaxon_1269296 a rdfs:Class ; rdfs:label "Coronavirus BtCoV/BRA119/Car_per/BRA/2009" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:NCBITaxon_384341 a rdfs:Class ; rdfs:label "Human coronavirus NO/0835/04" ; rdfs:subClassOf obo:NCBITaxon_384335 . obo:OPMI_0000558 a rdfs:Class ; rdfs:label "device exposure end datetime"@en ; rdfs:comment "The date and time on which a device exposure ends." ; rdfs:subClassOf obo:OPMI_0000556 . obo:CHEBI_22333 a rdfs:Class ; rdfs:label "alkylating agent" ; rdfs:comment "Highly reactive chemical that introduces alkyl radicals into biologically active molecules and thereby prevents their proper functioning. It could be used as an antineoplastic agent, but it might be very toxic, with carcinogenic, mutagenic, teratogenic, and immunosuppressant actions. It could also be used as a component of poison gases." ; rdfs:subClassOf obo:CHEBI_25435 . obo:GO_0071216 a rdfs:Class ; rdfs:label "cellular response to biotic stimulus" ; rdfs:comment "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a biotic stimulus, a stimulus caused or produced by a living organism." ; rdfs:subClassOf obo:GO_0009607 , obo:GO_0051716 . obo:CIDO_0000654 a rdfs:Class ; rdfs:label "Q27* in SARS-CoV-2 NS8 protein" ; rdfs:comment "An AA mutation or AA variant that has mutated an amino acid at position 27 into a stop mutation." ; rdfs:subClassOf obo:CIDO_0001150 . obo:CHEBI_25696 a rdfs:Class ; rdfs:label "organic anion" ; rdfs:comment "Any organic ion with a net negative charge." ; rdfs:subClassOf obo:CHEBI_22563 , obo:CHEBI_25699 . obo:NCBITaxon_2042552 a rdfs:Class ; rdfs:label "Coronavirus PREDICT CoV-25" ; rdfs:subClassOf obo:NCBITaxon_366617 . obo:CHEBI_291342 a rdfs:Class ; rdfs:label "desloratadine" ; rdfs:comment "Loratadine in which the ethoxycarbonyl group attached to the piperidine ring is replaced by hydrogen. The major metabolite of loratidine, desloratadine is an antihistamine which is used for the symptomatic relief of allergic conditions including rhinitis and chronic urticaria. It does not readily enter the central nervous system, so does not cause drowsiness." ; rdfs:subClassOf obo:CHEBI_48593 . obo:CHEBI_51151 a rdfs:Class ; rdfs:label "dipolar compound" ; rdfs:comment "An organic molecule that is electrically neutral carrying a positive and a negative charge in one of its major canonical descriptions. In most dipolar compounds the charges are delocalized; however the term is also applied to species where this is not the case." ; rdfs:subClassOf obo:CHEBI_72695 . obo:NCBITaxon_2720068 a rdfs:Class ; rdfs:label "unclassified Sarbecovirus" ; rdfs:subClassOf obo:NCBITaxon_2509511 . obo:CIDO_0020091 a rdfs:Class ; rdfs:label "COVID-19 Coronavirus Real Time PCR Kit" ; rdfs:seeAlso ; rdfs:subClassOf obo:CIDO_0000454 . obo:CHEBI_50990 a rdfs:Class ; rdfs:label "thiazolidinediones" ; rdfs:comment "A thiadiazolidine in which the 1,3-thiazolidine ring is substituted by two oxo groups." ; rdfs:subClassOf obo:CHEBI_35622 . obo:PR_Q7Z4Q2 a rdfs:Class ; rdfs:label "HEAT repeat-containing protein 3 (human)" ; rdfs:comment "A HEAT repeat-containing protein 3 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000029067 , obo:PR_000029538 . obo:PR_Q9BV73 a rdfs:Class ; rdfs:label "centrosome-associated protein CEP250 (human)" ; rdfs:comment "A centrosome-associated protein CEP250 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000005347 , obo:PR_000029067 . obo:CIDO_0001069 a rdfs:Class ; rdfs:label "SARS-CoV2 orf9c protein binding to human WFS1" ; rdfs:comment "SARS-CoV2 orf9c protein binding to human WFS1, as evidented by an affinity-purification mass spectrometry experiment" ; rdfs:subClassOf obo:CIDO_0000054 . obo:HP_0012115 a rdfs:Class ; rdfs:label "Hepatitis" ; rdfs:comment "Inflammation of the liver." ; rdfs:subClassOf obo:HP_0012649 , obo:HP_0410042 . obo:NCBITaxon_1403204 a rdfs:Class ; rdfs:label "Coronavirus PgCoV-2" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:PR_000008636 a rdfs:Class ; rdfs:label "3-hydroxy-3-methylglutaryl-coenzyme A reductase" ; rdfs:comment "A protein that is a translation product of the human HMGCR gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:NCBITaxon_76583 a rdfs:Class ; rdfs:label "Puffinosis coronavirus" ; rdfs:subClassOf obo:NCBITaxon_694005 . obo:PR_Q13873 a rdfs:Class ; rdfs:label "bone morphogenetic protein receptor type-2 (human)" ; rdfs:comment "A BMP receptor type-2 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000000037 , obo:PR_000029067 . obo:BFO_0000027 a rdfs:Class ; rdfs:label "object aggregate"@en ; rdfs:subClassOf obo:BFO_0000040 . obo:PR_P35241 a rdfs:Class ; rdfs:label "radixin (human)" ; rdfs:comment "A radixin that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000003009 , obo:PR_000029067 . obo:PR_P37231 a rdfs:Class ; rdfs:label "peroxisome proliferator-activated receptor gamma (human)" ; rdfs:comment "A peroxisome proliferator-activated receptor gamma that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000013058 , obo:PR_000029067 . obo:PR_000005585 a rdfs:Class ; rdfs:label "dual specificity protein kinase CLK2" ; rdfs:comment "A protein that is a translation product of the human CLK2 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:OPMI_0000570 a rdfs:Class ; rdfs:label "drug refills specification"@en ; rdfs:comment "An action specification that represents the intended refills at time of the prescription." ; rdfs:subClassOf obo:IAO_0000007 . obo:HP_0012378 a rdfs:Class ; rdfs:label "Fatigue" ; rdfs:comment "A subjective feeling of tiredness characterized by a lack of energy and motivation." ; rdfs:subClassOf obo:HP_0025142 . obo:CHEBI_83812 a rdfs:Class ; rdfs:label "non-proteinogenic amino acid derivative" ; rdfs:comment "Any derivative of a non-proteinogenic amino acid resulting from reaction at an amino group or carboxy group, or from the replacement of any hydrogen by a heteroatom." ; rdfs:subClassOf obo:CHEBI_83821 . obo:NCBITaxon_745728 a rdfs:Class ; rdfs:label "Coronavirus P.pipi/VM312/2008/NLD" ; rdfs:subClassOf obo:NCBITaxon_696098 . obo:OPMI_0000487 a rdfs:Class ; rdfs:label "visit start date"@en ; rdfs:comment "The date on which a visit starts. In the case of an inpatient visit this should be the date the patient was admitted to the hospital or institution. In all other cases this should be the date of the patient-provider interaction." ; rdfs:subClassOf obo:OPMI_0000285 . obo:CHEBI_59131 a rdfs:Class ; rdfs:label "5-chlorosalicylate" ; rdfs:comment "Conjugate base of 5-chlorosalicylic acid." ; rdfs:subClassOf obo:CHEBI_23133 , obo:CHEBI_24675 . obo:PR_Q04724 a rdfs:Class ; rdfs:label "transducin-like enhancer protein 1 (human)" ; rdfs:comment "A transducin-like enhancer protein 1 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000016372 , obo:PR_000029067 . obo:CIDO_0000795 a rdfs:Class ; rdfs:label "SARS-CoV2 nsp1 protein binding to human PRIM1" ; rdfs:comment "SARS-CoV2 nsp1 protein binding to human PRIM1, as evidented by an affinity-purification mass spectrometry experiment" ; rdfs:subClassOf obo:CIDO_0000062 . obo:DOID_0070086 a rdfs:Class ; rdfs:label "schizophrenia 10" ; rdfs:comment "A schizophrenia that has_material_basis_in an autosomal dominant mutation of SCZD10 on chromosome 15q15." ; rdfs:subClassOf obo:DOID_0050736 , obo:DOID_5419 . obo:PR_000007120 a rdfs:Class ; rdfs:label "ephrin type-A receptor 1" ; rdfs:comment "An ephrin receptor that is a translation product of the human EPHA1 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000025845 . obo:NCIT_C17005 a rdfs:Class ; rdfs:label "Population Group" ; rdfs:comment "A group of individuals united by a common factor (e.g., geographic location, ethnicity, disease, age, gender)" ; rdfs:subClassOf obo:BFO_0000040 . obo:CIDO_0001074 a rdfs:Class ; rdfs:label "AA variant in SARS-CoV-2 nsp3 protein"@en ; rdfs:comment "An AA variant in SARS-CoV-2 nsp3 protein. Equivalent to an AA variant in SARS-CoV-2 rep 1ab with an AA position of 819 - 2740." ; rdfs:subClassOf obo:CIDO_0000714 . obo:UBERON_0003126 a rdfs:Class ; rdfs:label "trachea" ; rdfs:comment "The trachea is the portion of the airway that attaches to the bronchi as it branches [GO:dph]." ; rdfs:subClassOf obo:UBERON_0000465 . a rdfs:Class ; rdfs:label "Immunoproliferative Disorders [Disease/Finding]" ; rdfs:subClassOf . obo:DRON_00075906 a rdfs:Class ; rdfs:label "Tamoxifen 20 MG Oral Tablet [Barr - Tamoxifen Citrate]" ; rdfs:subClassOf obo:DRON_00046109 . obo:NCBITaxon_1346294 a rdfs:Class ; rdfs:label "Betacoronavirus BtCoV/KCR22/Pte_par/CRC/2012" ; rdfs:subClassOf obo:NCBITaxon_696098 . obo:NCBITaxon_1515641 a rdfs:Class ; rdfs:label "Bean goose coronavirus" ; rdfs:subClassOf obo:NCBITaxon_749416 . obo:PR_000010134 a rdfs:Class ; rdfs:label "mitogen-activated protein kinase kinase kinase 15" ; rdfs:comment "A protein that is a translation product of the human MAP3K15 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:NCBITaxon_389252 a rdfs:Class ; rdfs:label "Bat coronavirus (BtCoV/A434/2005)" ; rdfs:subClassOf obo:NCBITaxon_389126 . obo:IAO_0000100 a rdfs:Class ; rdfs:label "data set"@en ; rdfs:comment "A data item that is an aggregate of other data items of the same type that have something in common. Averages and distributions can be determined for data sets."@en ; rdfs:subClassOf obo:IAO_0000027 . obo:RO_0002351 a rdf:Property ; rdfs:label "has member"@en ; rdfs:comment "has member is a mereological relation between a collection and an item." ; rdfs:range ; rdfs:subPropertyOf obo:BFO_0000051 . obo:NCBITaxon_1788492 a rdfs:Class ; rdfs:label "Rhinolophus bat coronavirus BtCoV/4030-1" ; rdfs:subClassOf obo:NCBITaxon_2664420 . a rdfs:Class ; rdfs:label "Thrombosis [Disease/Finding]" ; rdfs:subClassOf . obo:PR_Q9HAZ1 a rdfs:Class ; rdfs:label "dual specificity protein kinase CLK4 (human)" ; rdfs:comment "A dual specificity protein kinase CLK4 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000005587 , obo:PR_000029067 . obo:NCBITaxon_2509502 a rdfs:Class ; rdfs:label "Nobecovirus" ; rdfs:subClassOf obo:NCBITaxon_694002 . a rdfs:Class ; rdfs:label "Kidney Diseases [Disease/Finding]" ; rdfs:subClassOf . a rdfs:Class ; rdfs:label "Macrolides [Chemical/Ingredient]" ; rdfs:subClassOf , , . obo:GO_0002237 a rdfs:Class ; rdfs:label "response to molecule of bacterial origin" ; rdfs:comment "Any process that results in a change in state or activity of an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus by molecules of bacterial origin such as peptides derived from bacterial flagellin." ; rdfs:subClassOf obo:GO_0010033 , obo:GO_0043207 . obo:DRON_00059506 a rdfs:Class ; rdfs:label "Fluphenazine Hydrochloride 1.5 MG / Nortriptyline 30 MG Oral Tablet" ; rdfs:subClassOf obo:DRON_00021964 . obo:CIDO_0000773 a rdfs:Class ; rdfs:label "SARS-CoV2 M protein binding to human TUBGCP2" ; rdfs:comment "SARS-CoV2 M protein binding to human TUBGCP2, as evidented by an affinity-purification mass spectrometry experiment" ; rdfs:subClassOf obo:CIDO_0000055 . obo:CIDO_0000431 a rdfs:Class ; rdfs:label "COVID-19 immune marker role"@en ; rdfs:subClassOf obo:OPMI_0000441 . obo:CHEBI_83228 a rdfs:Class ; rdfs:label "L-alpha-amino acid residue" ; rdfs:comment "An alpha-amino-acid residue derived from an L-alpha-amino acid." ; rdfs:subClassOf obo:CHEBI_33710 . obo:NCBITaxon_305404 a rdfs:Class ; rdfs:label "SARS coronavirus A030" ; rdfs:subClassOf obo:NCBITaxon_694009 . obo:CHEBI_22860 a rdfs:Class ; rdfs:label "amino-acid betaine" ; rdfs:comment "Any amino acid-derived zwitterion - such as glycine betaine (N,N,N-trimethylammonioacetate) - in which the ammonium nitrogen carries methyl substituents and bears no hydrogen atoms." ; rdfs:subClassOf obo:CHEBI_35284 , obo:CHEBI_83821 . obo:VO_0005166 a rdfs:Class ; rdfs:label "BBIBP-CorV" ; rdfs:comment "A SARS-CoV-2 inactivated whole virus vaccine that produced in Vero cells that is developed by the Beijing Institute of Biological Products." ; rdfs:subClassOf obo:VO_0005266 . obo:NCBITaxon_2509476 a rdfs:Class ; rdfs:label "Cegacovirus" ; rdfs:subClassOf obo:NCBITaxon_694013 . obo:CIDO_0000025 a rdfs:Class ; rdfs:label "drive-thru COVID-19 testing entity"@en ; rdfs:comment "An organization that has members to perform COVID-19 test for patients who drive through to a specifc location" ; rdfs:subClassOf obo:OBI_0000245 . obo:VO_0005226 a rdfs:Class ; rdfs:label "Razi Cov Pars"@en ; rdfs:comment "A SARS-CoV-2 protein subunit vaccine manufactured by the Razi Vaccine and Serum Research Institute with a Spike protein antigen" ; rdfs:subClassOf obo:VO_0005269 . obo:NCBITaxon_10114 a rdfs:Class ; rdfs:label "Rattus" ; rdfs:subClassOf obo:NCBITaxon_39107 . obo:PR_P62750 a rdfs:Class ; rdfs:label "60S ribosomal protein L23a (human)" ; rdfs:comment "A 60S ribosomal protein L23a that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000014204 , obo:PR_000029067 . obo:CIDO_0000826 a rdfs:Class ; rdfs:label "SARS-CoV2 nsp13 protein binding to human CENPF" ; rdfs:comment "SARS-CoV2 nsp13 protein binding to human CENPF, as evidented by an affinity-purification mass spectrometry experiment" ; rdfs:subClassOf obo:CIDO_0000058 . obo:NCBITaxon_434614 a rdfs:Class ; rdfs:label "Raccoon dog coronavirus GZ43/2003" ; rdfs:subClassOf obo:NCBITaxon_11153 . obo:VO_0005277 a rdfs:Class ; rdfs:label "mRNA-1273.211"@en ; rdfs:comment "A multivalent SARS-CoV-2 mRNA booster vaccine which combines mRNA-1273, Moderna’s authorized vaccine against ancestral strains, and mRNA-1273.351 in a single vaccine at the 50 µg dose level and lower." ; rdfs:subClassOf obo:VO_0005198 . obo:GO_0015318 a rdfs:Class ; rdfs:label "inorganic molecular entity transmembrane transporter activity" ; rdfs:comment "Enables the transfer of an inorganic molecular entity from the outside of a cell to the inside of the cell across a membrane. An inorganic molecular entity is a molecular entity that contains no carbon." ; rdfs:subClassOf obo:GO_0022857 . obo:PR_P10721 a rdfs:Class ; rdfs:label "mast/stem cell growth factor receptor Kit (human)" ; rdfs:comment "A mast/stem cell growth factor receptor that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000002065 , obo:PR_000029067 . obo:CHEBI_35238 a rdfs:Class ; rdfs:label "amino acid zwitterion" ; rdfs:comment "The zwitterionic form of an amino acid having a negatively charged carboxyl group and a positively charged amino group." ; rdfs:subClassOf obo:CHEBI_27369 . obo:NCBITaxon_267388 a rdfs:Class ; rdfs:label "SARS coronavirus Sin849" ; rdfs:subClassOf obo:NCBITaxon_694009 . obo:PR_P29122 a rdfs:Class ; rdfs:label "proprotein convertase subtilisin/kexin type 6 (human)" ; rdfs:comment "A proprotein convertase subtilisin/kexin type 6 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000012438 , obo:PR_000029067 . obo:DOID_1742 a rdfs:Class ; rdfs:label "drug psychosis" ; rdfs:subClassOf obo:DOID_1203 . obo:DRON_00023295 a rdfs:Class ; rdfs:label "Reserpine / Trichlormethiazide Oral Tablet" ; rdfs:subClassOf obo:DRON_00000022 . obo:OAE_0001147 a rdfs:Class ; rdfs:label "lymphadenopathy AE" ; rdfs:comment "an immune system disorder AE that has an outcome of lymphadenopathy, which is a term meaning \"disease of the lymph nodes\" . It is generally a disease or inflammation of the lymph nodes, could be due to infection, auto-immune disease or malignancy" ; rdfs:subClassOf obo:OAE_0000476 . obo:NCBITaxon_265125 a rdfs:Class ; rdfs:label "SARS coronavirus xw002" ; rdfs:subClassOf obo:NCBITaxon_694009 . obo:PR_P28845 a rdfs:Class ; rdfs:label "11-beta-hydroxysteroid dehydrogenase 1 (human)" ; rdfs:comment "An 11-beta-hydroxysteroid dehydrogenase 1 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000008770 , obo:PR_000029067 . obo:DRON_00013825 a rdfs:Class ; rdfs:label "interferon beta-1b" ; rdfs:subClassOf obo:OBI_0000047 . obo:NCBITaxon_1788473 a rdfs:Class ; rdfs:label "Miniopterus bat coronavirus BtCoV/4023-1" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:NCBITaxon_1076420 a rdfs:Class ; rdfs:label "Alphacoronavirus N.las/F/Spain/2007" ; rdfs:subClassOf obo:NCBITaxon_366617 . obo:GO_0022407 a rdfs:Class ; rdfs:label "regulation of cell-cell adhesion" ; rdfs:comment "Any process that modulates the frequency, rate or extent of attachment of a cell to another cell." ; rdfs:subClassOf obo:GO_0030155 . obo:PR_000045384 a rdfs:Class ; rdfs:label "protein kinase D" ; rdfs:comment "A protein that is a member of the phorbol ester (and diacylglycerol) receptor/protein kinase class. The canonical protein sequence has a core domain architecture consisting of two copies of the Phorbol esters/diacylglycerol binding domain (C1 domain) (Pfam:PF00130), followed by a PH domain (Pfam:PF00169), and a Protein kinase domain (Pfam:PF00069)." ; rdfs:subClassOf obo:PR_000000001 . obo:NCBITaxon_2042573 a rdfs:Class ; rdfs:label "Coronavirus PREDICT CoV-47" ; rdfs:subClassOf obo:NCBITaxon_366617 . obo:CHEBI_472805 a rdfs:Class ; rdfs:label "ouabain" ; rdfs:comment "A steroid hormone that is a multi-hydroxylated alpha-L-rhamnosyl cardenoloide. It binds to and inhibits the plasma membrane Na(+)/K(+)-ATPase (sodium pump). It has been isolated naturally from Strophanthus gratus." ; rdfs:subClassOf obo:CHEBI_19129 , obo:CHEBI_26764 , obo:CHEBI_27848 , obo:CHEBI_36862 , obo:CHEBI_38092 , obo:CHEBI_38195 . obo:CIDO_0000812 a rdfs:Class ; rdfs:label "SARS-CoV2 nsp12 protein binding to human RBM41" ; rdfs:comment "SARS-CoV2 nsp12 protein binding to human RBM41, as evidented by an affinity-purification mass spectrometry experiment" ; rdfs:subClassOf obo:CIDO_0000057 . obo:NCBITaxon_727990 a rdfs:Class ; rdfs:label "Ferret systemic coronavirus WADL" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:NCBITaxon_903635 a rdfs:Class ; rdfs:label "Kenya bat coronavirus BtKY97" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:PR_000001710 a rdfs:Class ; rdfs:label "sphingosine 1-phosphate receptor 5" ; rdfs:comment "A lysophospholipid (S1P) receptor that is a translation product of the human S1PR5 gene or a 1:1 ortholog thereof. Although widely expressed in the brain, most prominently in the corpus callosum, it is detected at a low level in most tissues." ; rdfs:subClassOf obo:PR_000001673 . obo:PR_000001776 a rdfs:Class ; rdfs:label "inhibitor of nuclear factor kappa-B kinase subunit beta" ; rdfs:comment "An inhibitor of nuclear factor kappa-B kinase complex alpha/beta subunits that is a translation product of the human IKBKB gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000001774 . obo:PR_Q86UE8 a rdfs:Class ; rdfs:label "serine/threonine-protein kinase tousled-like 2 (human)" ; rdfs:comment "A serine/threonine-protein kinase tousled-like 2 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000016378 , obo:PR_000029067 . obo:NCBITaxon_290028 a rdfs:Class ; rdfs:label "Human coronavirus HKU1" ; rdfs:subClassOf obo:NCBITaxon_2509481 . a rdfs:Class ; rdfs:label "Cardenolides [Chemical/Ingredient]" ; rdfs:subClassOf . obo:NCBITaxon_258969 a rdfs:Class ; rdfs:label "SARS coronavirus TW6" ; rdfs:subClassOf obo:NCBITaxon_694009 . obo:DRON_00020190 a rdfs:Class ; rdfs:label "ivacaftor" ; rdfs:subClassOf obo:OBI_0000047 . obo:OBI_1110014 a rdfs:Class ; rdfs:label "epitope binding by adaptive immune receptor"@en ; rdfs:comment "is the process in which an adaptive immune receptor binds to a material entity (realizing its disposition). The binding affinity is significant enough to trigger an immune response. Specifically, transient non-specific binding of adaptive immune receptors occurring during immune surveillance is not considered significant binding."@en ; rdfs:subClassOf obo:GO_0008150 . obo:CIDO_0020080 a rdfs:Class ; rdfs:label "Clip COVID Rapid Antigen Test" ; rdfs:seeAlso ; rdfs:subClassOf obo:CIDO_0000454 . obo:CHEBI_38769 a rdfs:Class ; rdfs:label "indazoles" ; rdfs:subClassOf obo:CHEBI_27171 , obo:CHEBI_38101 . a rdfs:Class ; rdfs:label "Eosinophilia [Disease/Finding]" ; rdfs:subClassOf . a rdfs:Class ; rdfs:label "Cell Membrane Alteration [PE]" ; rdfs:subClassOf . obo:PR_000015627 a rdfs:Class ; rdfs:label "signal recognition particle subunit SRP72" ; rdfs:comment "A protein that is a translation product of the human SRP72 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:PR_Q13554 a rdfs:Class ; rdfs:label "calcium/calmodulin-dependent protein kinase type II subunit beta (human)" ; rdfs:comment "A calcium/calmodulin-dependent protein kinase type II subunit beta that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000003200 , obo:PR_000029067 . obo:CIDO_0020186 a rdfs:Class ; rdfs:label "LifeHope 2019-nCoV Real-Time RT-PCR Diagnostic Panel" ; rdfs:seeAlso ; rdfs:subClassOf obo:CIDO_0000454 . a rdfs:Class ; rdfs:label "Pneumonia, Mycoplasma [Disease/Finding]" ; rdfs:subClassOf , . obo:GO_0007611 a rdfs:Class ; rdfs:label "learning or memory" ; rdfs:comment "The acquisition and processing of information and/or the storage and retrieval of this information over time." ; rdfs:subClassOf obo:GO_0007610 , obo:GO_0050877 . obo:NCBITaxon_228409 a rdfs:Class ; rdfs:label "SARS coronavirus BJ03" ; rdfs:subClassOf obo:NCBITaxon_694009 . obo:PR_P08185 a rdfs:Class ; rdfs:label "corticosteroid-binding globulin (human)" ; rdfs:comment "A corticosteroid-binding globulin that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000014686 , obo:PR_000029067 . obo:NCBITaxon_1415844 a rdfs:Class ; rdfs:label "Bat SARS-like coronavirus Rs4090" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:PR_000004191 a rdfs:Class ; rdfs:label "androgen receptor" ; rdfs:comment "A protein that is a translation product of the human AR gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:PR_000014836 a rdfs:Class ; rdfs:label "sex hormone-binding globulin" ; rdfs:comment "A protein that is a translation product of the human SHBG gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:CHEBI_46895 a rdfs:Class ; rdfs:label "lipopeptide" ; rdfs:comment "A compound consisting of a peptide with attached lipid." ; rdfs:subClassOf obo:CHEBI_16670 , obo:CHEBI_18059 . obo:NCBITaxon_1881090 a rdfs:Class ; rdfs:label "Rhinolophus monoceros coronavirus" ; rdfs:subClassOf obo:NCBITaxon_2664420 . a rdfs:Class ; rdfs:label "Pemphigus [Disease/Finding]" ; rdfs:subClassOf , . obo:NCBITaxon_2707191 a rdfs:Class ; rdfs:label "Gentoo penguin virus" ; rdfs:subClassOf obo:NCBITaxon_2724161 . obo:DRON_00017078 a rdfs:Class ; rdfs:label "Emetine" ; rdfs:subClassOf obo:OBI_0000047 . obo:CHEBI_33700 a rdfs:Class ; rdfs:label "proteinogenic amino-acid residue" ; rdfs:subClassOf obo:CHEBI_33710 . obo:NCBITaxon_2697049 a rdfs:Class ; rdfs:label "severe acute respiratory syndrome coronavirus 2" ; rdfs:comment """The list of the marker variants is as follows (as of 3/6/2021): S: C8782T,T28144C includes NS8-L84S L: C241,C3037,A23403,C8782,G11083,G26144,T28144 (early clade markers in WIV04-reference sequence) V: G11083T,G26144T NSP6-L37F + NS3-G251V G: C241T,C3037T,A23403G includes S-D614G GH: C241T,C3037T,A23403G,G25563T includes S-D614G + NS3-Q57H GR: C241T,C3037T,A23403G,G28882A includes S-D614G + N-G204R GV: C241T,C3037T,A23403G,C22227T includes S-D614G + S-A222V GRY: C241T,C3037T,21765-21770del,21991-21993del,A23063T,A23403G,G28882A includes S-H69del, S-V70del, S-Y144del, S-N501Y + S-D614G + N-G204R Reference: https://www.gisaid.org/references/statements-clarifications/clade-and-lineage-nomenclature-aids-in-genomic-epidemiology-of-active-hcov-19-viruses/""" ; rdfs:subClassOf obo:NCBITaxon_10239 , obo:NCBITaxon_2509511 , obo:NCBITaxon_694002 , obo:NCBITaxon_694009 . obo:NCBITaxon_249087 a rdfs:Class ; rdfs:label "SARS coronavirus LC5" ; rdfs:subClassOf obo:NCBITaxon_694009 . obo:CHEBI_367163 a rdfs:Class ; rdfs:label "darunavir" ; rdfs:comment "An N,N-disubstituted benzenesulfonamide bearing an unsubstituted amino group at the 4-position, used for the treatment of HIV infection. A second-generation HIV protease inhibitor, darunavir was designed to form robust interactions with the protease enzyme from many strains of HIV, including those from treatment-experienced patients with multiple resistance mutations to other protease inhibitors." ; rdfs:subClassOf obo:CHEBI_23003 , obo:CHEBI_35358 , obo:CHEBI_47790 . obo:CHEBI_50584 a rdfs:Class ; rdfs:label "alkyl alcohol" ; rdfs:comment "An aliphatic alcohol in which the aliphatic alkane chain is substituted by a hydroxy group at unspecified position." ; rdfs:subClassOf obo:CHEBI_2571 . obo:PR_000029950 a rdfs:Class ; rdfs:label "glutathione S-transferase pi" ; rdfs:comment "Category=family. Note: Classification described in wikipedia. [Wikipedia:Glutathione_S-transferase]" ; rdfs:subClassOf obo:PR_000029945 . obo:CHEBI_29438 a rdfs:Class ; rdfs:label "methanide" ; rdfs:subClassOf obo:CHEBI_38222 . obo:OBI_0600028 a rdfs:Class ; rdfs:label "artificially induced reverse transcription"@en ; rdfs:comment "a protocol with the objective to transcribe single-stranded RNA into complementary DNA (cDNA)"@en ; rdfs:subClassOf obo:OBI_0000094 . obo:NCBITaxon_749439 a rdfs:Class ; rdfs:label "Western sandpiper coronavirus KR-28" ; rdfs:subClassOf obo:NCBITaxon_749416 . obo:CHEBI_46690 a rdfs:Class ; rdfs:label "reserpic acid" ; rdfs:subClassOf obo:CHEBI_27358 . obo:CIDO_0000477 a rdfs:Class ; rdfs:label "CVQSFNGIKVLPPIL" ; rdfs:comment "A coronavirus epitope that is part of some S protein from HCoV HKU1 composed of the following amino acids CVQSFNGIKVLPPIL" ; rdfs:subClassOf obo:CIDO_0000450 . a rdfs:Class ; rdfs:label "Schizophrenia and Disorders with Psychotic Features [Disease/Finding]" ; rdfs:subClassOf . obo:CHEBI_58922 a rdfs:Class ; rdfs:label "Ile(5)-angiotensin II (1-7) dizwitterion" ; rdfs:comment "Dizwitterionic form of Ile(5)-angiotensin II (1-7) having both carboxy groups deprotonated and the aspartyl amino group and arginine side-chain protonated." ; rdfs:subClassOf obo:CHEBI_35238 . obo:UBERON_0001558 a rdfs:Class ; rdfs:label "lower respiratory tract" ; rdfs:comment "The segment of the respiratory tract that starts proximally with the trachea and includes all distal structures including the lungs[WP,modified]" ; rdfs:subClassOf obo:UBERON_0000465 . obo:NCBITaxon_1511624 a rdfs:Class ; rdfs:label "Coronavirus BtCoV/M8/HUN/2013" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:APOLLO_SV_00000001 a rdfs:Class ; rdfs:label "epidemic model"@en ; rdfs:comment "A disease transmission model whose concretization is realized as a simulation of infectious disease epidemic or infectious disease pandemic."@en ; rdfs:subClassOf obo:APOLLO_SV_00000174 . obo:CIDO_0000557 a rdfs:Class ; rdfs:label "FPKGYVMGLFRSYKT" ; rdfs:comment "A coronavirus epitope that is part of some S protein from HCoV HKU1 composed of the following amino acids FPKGYVMGLFRSYKT" ; rdfs:subClassOf obo:CIDO_0000450 . obo:CHEBI_66919 a rdfs:Class ; rdfs:label "ruxolitinib" ; rdfs:comment "A pyrazole substituted at position 1 by a 2-cyano-1-cyclopentylethyl group and at position 3 by a pyrrolo[2,3-d]pyrimidin-4-yl group. Used as the phosphate salt for the treatment of patients with intermediate or high-risk myelofibrosis, including primary myelofibrosis, post-polycythemia vera myelofibrosis and post-essential thrombocythemia myelofibrosis." ; rdfs:subClassOf obo:CHEBI_18379 , obo:CHEBI_26410 , obo:CHEBI_38670 . obo:NCBITaxon_267391 a rdfs:Class ; rdfs:label "SARS coronavirus SinP2" ; rdfs:subClassOf obo:NCBITaxon_694009 . obo:VO_0004996 a rdfs:Class ; rdfs:label "AdCLD-CoV19"@en ; rdfs:comment "A SARS-CoV-2 replication-defective human adenovirus type 5/35 vector based vaccine expressing the S protein." ; rdfs:subClassOf obo:VO_0005200 . obo:PR_000012441 a rdfs:Class ; rdfs:label "cyclin-dependent kinase 16" ; rdfs:comment "A CDK2-related kinase that is a translation product of the human CDK16 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000003270 . obo:PR_O60285 a rdfs:Class ; rdfs:label "NUAK family SNF1-like kinase 1 (human)" ; rdfs:comment "A NUAK family SNF1-like kinase 1 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000011473 , obo:PR_000029067 . obo:PR_000006606 a rdfs:Class ; rdfs:label "DNA (cytosine-5)-methyltransferase 1" ; rdfs:comment "A protein that is a translation product of the human DNMT1 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . a rdfs:Class ; rdfs:label "CHLORPROMAZINE" ; rdfs:subClassOf . obo:NCBITaxon_749421 a rdfs:Class ; rdfs:label "Black-headed gull coronavirus CIR-66185" ; rdfs:subClassOf obo:NCBITaxon_749416 . obo:HP_0011687 a rdfs:Class ; rdfs:label "AV nodal tachycardia" ; rdfs:comment "A type of supraventricular tachycardia that originates in the atrioventricular node." ; rdfs:subClassOf obo:HP_0004755 . obo:UBERON_0000992 a rdfs:Class ; rdfs:label "ovary" ; rdfs:comment "the gonad of a female organism which contains germ cells" ; rdfs:subClassOf obo:UBERON_0000465 . obo:NCBITaxon_11137 a rdfs:Class ; rdfs:label "Human coronavirus 229E" ; rdfs:subClassOf obo:NCBITaxon_2509480 . obo:GO_0060341 a rdfs:Class ; rdfs:label "regulation of cellular localization" ; rdfs:comment "Any process that modulates the frequency, rate or extent of a process in which a cell, a substance, or a cellular entity is transported to, or maintained in a specific location within or in the membrane of a cell." ; rdfs:subClassOf obo:GO_0032879 , obo:GO_0050794 . obo:DOID_9255 a rdfs:Class ; rdfs:label "frontotemporal dementia" ; rdfs:comment "A dementia characterized by progressive neuronal loss predominantly involving the frontal and/or temporal lobes of the brain resulting in a gradual and progressive decline in behavior or language." ; rdfs:subClassOf obo:DOID_1307 , obo:DOID_936 . obo:NCBITaxon_702702 a rdfs:Class ; rdfs:label "Bovine coronavirus Bubalus/153/ITA/2008" ; rdfs:subClassOf obo:NCBITaxon_11128 . obo:VO_0005160 a rdfs:Class ; rdfs:label "WIBP-CorV" ; rdfs:comment "A SARS-CoV-2 inactivated whole virus vaccine that is developed by the Wuhan Institute of Biological Products." ; rdfs:subClassOf obo:VO_0005266 . a rdfs:Class ; rdfs:label "Leukemia [Disease/Finding]" ; rdfs:subClassOf . obo:CHEBI_22478 a rdfs:Class ; rdfs:label "amino alcohol" ; rdfs:comment "An alcohol containing an amino functional group in addition to the alcohol-defining hydroxy group." ; rdfs:subClassOf obo:CHEBI_30879 , obo:CHEBI_50047 . a rdfs:Class ; rdfs:label "Neurologic Manifestations [Disease/Finding]" ; rdfs:subClassOf , . obo:CIDO_0000763 a rdfs:Class ; rdfs:label "SARS-CoV2 M protein binding to human PSMD8" ; rdfs:comment "SARS-CoV2 M protein binding to human PSMD8, as evidented by an affinity-purification mass spectrometry experiment" ; rdfs:subClassOf obo:CIDO_0000055 . obo:NCBITaxon_11153 a rdfs:Class ; rdfs:label "Canine coronavirus" ; rdfs:subClassOf obo:NCBITaxon_693997 . obo:NCBITaxon_2691596 a rdfs:Class ; rdfs:label "unclassified Decacovirus" ; rdfs:subClassOf obo:NCBITaxon_2509479 . obo:NCBITaxon_8457 a rdfs:Class ; rdfs:label "Sauropsida" ; rdfs:subClassOf obo:NCBITaxon_32524 . obo:DRON_00000033 a rdfs:Class ; rdfs:label "anti-malarial function of a drug product" ; rdfs:comment "a therapeutic function of a drug product that is realized by administration of the drug product resulting in creation of a material basis of a resistance to malaria infection disposition"@en ; rdfs:subClassOf obo:DRON_00000032 . obo:OBI_0002504 a rdfs:Class ; rdfs:label "digestive system fluid or secretion specimen" ; rdfs:comment "A specimen that is derived from digestive system fluid or secretion." ; rdfs:subClassOf obo:OBI_0001479 . obo:VO_0005266 a rdfs:Class ; rdfs:label "authorized inactivated COVID-19 vaccine"@en ; rdfs:subClassOf obo:VO_0005201 , obo:VO_0005264 . obo:NCBITaxon_441981 a rdfs:Class ; rdfs:label "Lesser Indian civet coronavirus Guangxi/D690/2005" ; rdfs:subClassOf obo:NCBITaxon_441985 . obo:NCBITaxon_694014 a rdfs:Class ; rdfs:label "Avian coronavirus" ; rdfs:subClassOf obo:NCBITaxon_2509487 . obo:CHEBI_9711 a rdfs:Class ; rdfs:label "triflupromazine" ; rdfs:comment "A member of the class of phenothiazines that is 10H-phenothiazine having a trifluoromethyl subsitituent at the 2-position and a 3-(dimethylamino)propyl group at the N-10 position." ; rdfs:subClassOf obo:CHEBI_32876 , obo:CHEBI_37143 , obo:CHEBI_38093 . obo:NCBITaxon_424370 a rdfs:Class ; rdfs:label "Bat coronavirus HKU9-4" ; rdfs:subClassOf obo:NCBITaxon_694006 . obo:NCBITaxon_347537 a rdfs:Class ; rdfs:label "Bat SARS CoV Rf1/2004" ; rdfs:subClassOf obo:NCBITaxon_694009 . a rdfs:Class ; rdfs:label "Spiro Compounds [Chemical/Ingredient]" ; rdfs:subClassOf . obo:GO_0051350 a rdfs:Class ; rdfs:label "negative regulation of lyase activity" ; rdfs:comment "Any process that stops or reduces the rate of lyase activity, the catalysis of the cleavage of C-C, C-O, C-N and other bonds by other means than by hydrolysis or oxidation, or conversely adding a group to a double bond." ; rdfs:subClassOf obo:GO_0043086 , obo:GO_0051339 . obo:CHEBI_46942 a rdfs:Class ; rdfs:label "oxanes" ; rdfs:comment "Any organic heteromonocyclic compoundthat is oxane or its substituted derivatives." ; rdfs:subClassOf obo:CHEBI_25693 , obo:CHEBI_38104 . obo:PR_Q7L7X3 a rdfs:Class ; rdfs:label "serine/threonine-protein kinase TAO1 (human)" ; rdfs:comment "A serine/threonine-protein kinase TAO1 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000016048 , obo:PR_000029067 . obo:VO_0005161 a rdfs:Class ; rdfs:label "ARCoV" ; rdfs:comment "A SARS-CoV-2 mRNA vaccine made of lipid nanoparticle-encapsulated mRNA (mRNA-LNP) encoding the receptor binding domain (RBD) of SARS-CoV-2 manufactured by Academy of Military Science (AMS), Walvax Biotechnology, and Suzhou Abogen Biosciences." ; rdfs:subClassOf obo:VO_0005198 . obo:PR_P07947 a rdfs:Class ; rdfs:label "tyrosine-protein kinase Yes (human)" ; rdfs:comment "A tyrosine-protein kinase Yes that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000017528 , obo:PR_000029067 . obo:PR_P07711 a rdfs:Class ; rdfs:label "procathepsin L (human)" ; rdfs:comment "A procathepsin L that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000006030 , obo:PR_000029067 . a rdfs:Class ; rdfs:label "Warts [Disease/Finding]" ; rdfs:subClassOf , . obo:NCBITaxon_249076 a rdfs:Class ; rdfs:label "SARS coronavirus HZS2-Fc" ; rdfs:subClassOf obo:NCBITaxon_694009 . obo:HP_0025142 a rdfs:Class ; rdfs:label "Constitutional symptom"@en ; rdfs:comment "A symptom or manifestation indicating a systemic or general effect of a disease and that may affect the general well-being or status of an individual." ; rdfs:subClassOf obo:HP_0000118 . obo:PR_000010189 a rdfs:Class ; rdfs:label "MAP/microtubule affinity-regulating kinase 4" ; rdfs:comment "A protein that is a translation product of the human MARK4 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . a rdfs:Class ; rdfs:label "Adrenergic Antagonists [MoA]" ; rdfs:subClassOf . obo:CIDO_0020078 a rdfs:Class ; rdfs:label "Cleveland Clinic SARS-CoV-2 Assay" ; rdfs:seeAlso ; rdfs:subClassOf obo:CIDO_0000454 . obo:PR_Q6P3R8 a rdfs:Class ; rdfs:label "serine/threonine-protein kinase Nek5 (human)" ; rdfs:comment "A serine/threonine-protein kinase Nek5 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000011131 , obo:PR_000029067 . obo:CHEBI_27364 a rdfs:Class ; rdfs:label "zinc molecular entity" ; rdfs:subClassOf obo:CHEBI_33673 . obo:CIDO_0000949 a rdfs:Class ; rdfs:label "SARS-CoV2 nsp9 protein binding to human FBLN5" ; rdfs:comment "SARS-CoV2 nsp9 protein binding to human FBLN5, as evidented by an affinity-purification mass spectrometry experiment" ; rdfs:subClassOf obo:CIDO_0000583 . obo:PR_000044637 a rdfs:Class ; rdfs:label "calcitonin receptor protein" ; rdfs:comment "A rhodopsin-like G-protein coupled receptor that is a translation product of the human CALCR or CALCRL genes, 1:1 orthologs thereof, or a semi-ortholog thereof." ; rdfs:subClassOf obo:PR_000001094 . obo:NCBITaxon_1458242 a rdfs:Class ; rdfs:label "Alphacoronavirus Myotis/13rs384_31/Italy/2012" ; rdfs:subClassOf obo:NCBITaxon_366617 . obo:GO_0051345 a rdfs:Class ; rdfs:label "positive regulation of hydrolase activity" ; rdfs:comment "Any process that activates or increases the frequency, rate or extent of hydrolase activity, the catalysis of the hydrolysis of various bonds." ; rdfs:subClassOf obo:GO_0043085 , obo:GO_0051336 . obo:NCBITaxon_1699326 a rdfs:Class ; rdfs:label "Myotis Bat Alphacoronavirus strain YNXY_16C" ; rdfs:subClassOf obo:NCBITaxon_366617 . obo:HP_0011843 a rdfs:Class ; rdfs:label "Abnormality of musculoskeletal physiology" ; rdfs:comment "An abnormality of the function of the skeletal system." ; rdfs:subClassOf obo:HP_0000924 , obo:HP_0033127 . obo:VO_0005136 a rdfs:Class ; rdfs:label "Ad41.MERS vaccine" ; rdfs:comment "A MERS recombinant vector made of Adenovirus type 41 used as vector for MERS-CoV S protein.’" ; rdfs:subClassOf obo:VO_0004900 . obo:PR_000008158 a rdfs:Class ; rdfs:label "glycosylphosphatidylinositol anchor attachment 1 protein" ; rdfs:comment "A protein that is a translation product of the human GPAA1 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:CIDO_0020197 a rdfs:Class ; rdfs:label "MAGLUMI 2019-nCoV IgM/IgG" ; rdfs:seeAlso ; rdfs:subClassOf obo:CIDO_0000454 . obo:OPMI_0000529 a rdfs:Class ; rdfs:label "condition end date"@en ; rdfs:comment "The date on which a condition ends." ; rdfs:subClassOf obo:OPMI_0000528 . obo:OBI_0001003 a rdfs:Class ; rdfs:label "agar stab storage" ; rdfs:comment "a storage process with input cell culture and agar and output agar stab for long time storage" ; rdfs:subClassOf obo:OBI_0302893 . a rdfs:Class ; rdfs:label "TAMOXIFEN CITRATE" ; rdfs:subClassOf . obo:CHEBI_48873 a rdfs:Class ; rdfs:label "cholinergic antagonist" ; rdfs:comment "Any drug that binds to but does not activate cholinergic receptors, thereby blocking the actions of acetylcholine or cholinergic agonists." ; rdfs:subClassOf obo:CHEBI_38323 . a rdfs:Class ; rdfs:label "Esophageal Motility Disorders [Disease/Finding]" ; rdfs:subClassOf . obo:NCBITaxon_1644141 a rdfs:Class ; rdfs:label "Bat coronavirus ANK045F" ; rdfs:subClassOf obo:NCBITaxon_696098 . obo:PATO_0002198 a rdfs:Class ; rdfs:label "quality of a substance" ; rdfs:comment "A quality inhering in a bearer by virtue of its constitution." ; rdfs:subClassOf obo:PATO_0001018 . obo:CIDO_0000589 a rdfs:Class ; rdfs:label "basic reproduction number of infection"@en ; rdfs:comment "In epidemiology, the basic reproduction number of an infection is the expected number of cases directly generated by one case in a population where all individuals are susceptible to infection." ; rdfs:seeAlso obo:APOLLO_SV_00000002 , obo:NCIT_C173777 ; rdfs:subClassOf obo:IAO_0000109 . a rdfs:Class ; rdfs:label "THIETHYLPERAZINE" ; rdfs:subClassOf . a rdfs:Class ; rdfs:label "imatinib [Chemical/Ingredient]" ; rdfs:subClassOf , . obo:NCBITaxon_1289554 a rdfs:Class ; rdfs:label "Coronavirus Mex_CoV-8" ; rdfs:subClassOf obo:NCBITaxon_366617 . obo:GO_0048856 a rdfs:Class ; rdfs:label "anatomical structure development" ; rdfs:comment "The biological process whose specific outcome is the progression of an anatomical structure from an initial condition to its mature state. This process begins with the formation of the structure and ends with the mature structure, whatever form that may be including its natural destruction. An anatomical structure is any biological entity that occupies space and is distinguished from its surroundings. Anatomical structures can be macroscopic such as a carpel, or microscopic such as an acrosome." ; rdfs:subClassOf obo:GO_0032502 . obo:CHEBI_49637 a rdfs:Class ; rdfs:label "hydrogen atom" ; rdfs:subClassOf obo:CHEBI_24835 , obo:CHEBI_25585 , obo:CHEBI_33559 . obo:NCBITaxon_1288694 a rdfs:Class ; rdfs:label "Bat coronavirus POA/2012/96" ; rdfs:subClassOf obo:NCBITaxon_366617 . obo:NCBITaxon_903621 a rdfs:Class ; rdfs:label "Kenya bat coronavirus BtKY83" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:NCBITaxon_33740 a rdfs:Class ; rdfs:label "Rat coronavirus (strain 681)" ; rdfs:subClassOf obo:NCBITaxon_31632 . obo:OBI_0001879 a rdfs:Class ; rdfs:label "reagent"@en ; rdfs:comment "A biological or chemical entity that bears a reagent role in virtue of it being intended for application in a scientific technique to participate in (or have molecular parts that participate in) a chemical reaction that facilitates the generation of data about some distinct entity, or the generation of some distinct material specified output." ; rdfs:subClassOf obo:BFO_0000040 , obo:OBI_0000047 . obo:CHEBI_33267 a rdfs:Class ; rdfs:label "elemental nitrogen" ; rdfs:subClassOf obo:CHEBI_33465 , obo:CHEBI_51143 . obo:NCBITaxon_1487705 a rdfs:Class ; rdfs:label "Rhinolophus hipposideros coronavirus" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:DRON_00018224 a rdfs:Class ; rdfs:label "everolimus" ; rdfs:subClassOf obo:OBI_0000047 . obo:VO_0005121 a rdfs:Class ; rdfs:label "MERS rRBD plus alum vaccine" ; rdfs:comment "A MERS subunit vaccine made of neutralizing monoclonal antibodiesagainst MERS-CoV which bind to the ribosomal binding domain (RBD) of the MERS-CoV S protein that was expressed by baculovirus-insect cell sf9-derived recombinant MERS-CoV." ; rdfs:subClassOf obo:VO_0004900 . obo:BFO_0000023 a rdfs:Class ; rdfs:label "role"@en ; rdfs:comment "A realizable entity the manifestation of which brings about some result or end that is not essential to a continuant in virtue of the kind of thing that it is but that can be served or participated in by that kind of continuant in some kinds of natural, social or institutional contexts."@en ; rdfs:subClassOf obo:BFO_0000017 . obo:CIDO_0000459 a rdfs:Class ; rdfs:label "CLIA certified Moderate complexity laboratory"@en ; rdfs:comment "A CLIA certified laboratory that is categorized as a moderate complexity defined by the criteria listed in 42CFR 493.17 based on the Clinical Laboratory Improvement Amendments (CLIA) regulattion." ; rdfs:subClassOf obo:CIDO_0000457 . obo:GO_0019076 a rdfs:Class ; rdfs:label "viral release from host cell" ; rdfs:comment "The dissemination of mature viral particles from the host cell, e.g. by cell lysis or the budding of virus particles from the cell membrane." ; rdfs:subClassOf obo:GO_0016032 , obo:GO_0052126 . obo:PR_000014612 a rdfs:Class ; rdfs:label "selenoprotein S" ; rdfs:comment "A protein that is a translation product of the human SELENOS gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:NCBITaxon_273522 a rdfs:Class ; rdfs:label "SARS coronavirus LLJ-2004" ; rdfs:subClassOf obo:NCBITaxon_694009 . a rdfs:Class ; rdfs:label "Central Nervous System Diseases [Disease/Finding]" ; rdfs:subClassOf . a rdfs:Class ; rdfs:label "Leukemia, Myeloid [Disease/Finding]" ; rdfs:subClassOf . a rdfs:Class ; rdfs:label "Connective Tissue Alteration [PE]" ; rdfs:subClassOf . obo:CHEBI_26401 a rdfs:Class ; rdfs:label "purines" ; rdfs:comment "A class of imidazopyrimidines that consists of purine and its substituted derivatives." ; rdfs:subClassOf obo:CHEBI_35875 . obo:CHEBI_35293 a rdfs:Class ; rdfs:label "fused compound" ; rdfs:subClassOf obo:CHEBI_33635 . obo:CIDO_0001010 a rdfs:Class ; rdfs:label "Anti-SARS-CoV-2 REGN-COV2" ; rdfs:subClassOf obo:CHEBI_23367 . obo:CIDO_0001127 a rdfs:Class ; rdfs:label "SARS-CoV2 orf8 protein binding to human PLAT"@en ; rdfs:comment "SARS-CoV2 orf8 protein binding to human PLAT, as evidented by an affinity-purification mass spectrometry experiment" ; rdfs:subClassOf obo:CIDO_0000051 . obo:VO_0005237 a rdfs:Class ; rdfs:label "SpFN"@en ; rdfs:comment "A SARS-CoV-2 protein subunit vaccine manufactured by Walter Reed Army Institute of Research" ; rdfs:subClassOf obo:VO_0005202 . obo:GO_0046883 a rdfs:Class ; rdfs:label "regulation of hormone secretion" ; rdfs:comment "Any process that modulates the frequency, rate or extent of the regulated release of a hormone from a cell." ; rdfs:subClassOf obo:GO_0010646 , obo:GO_0023051 , obo:GO_0065008 , obo:GO_1903530 . obo:CHEBI_9397 a rdfs:Class ; rdfs:label "tamoxifen citrate" ; rdfs:subClassOf obo:CHEBI_50744 . obo:CIDO_0000057 a rdfs:Class ; rdfs:label "SARS-CoV-2 Nsp12 protein interaction with host protein"@en ; rdfs:comment "A molecular interaction that has participant of the SARS-CoV-2 Nsp12 protein and a host protein" ; rdfs:subClassOf obo:CIDO_0000348 . obo:CIDO_0020045 a rdfs:Class ; rdfs:label "BinaxNOW COVID-19 Ag Card" ; rdfs:seeAlso ; rdfs:subClassOf obo:CIDO_0000454 . a rdfs:Class ; rdfs:label "Active Transporter Interactions [MoA]" ; rdfs:subClassOf . obo:DRON_00000022 a rdfs:Class ; rdfs:label "drug tablet"@en ; rdfs:comment "a solid object typically of discoid, spheroid, or elliptic-cylindrical shape or approximations thereof, that bears a clinical drug role."@en ; rdfs:subClassOf obo:BFO_0000030 . obo:CIDO_0000906 a rdfs:Class ; rdfs:label "SARS-CoV2 nsp7 protein binding to human NDUFAF2" ; rdfs:comment "SARS-CoV2 nsp7 protein binding to human NDUFAF2, as evidented by an affinity-purification mass spectrometry experiment" ; rdfs:subClassOf obo:CIDO_0000049 . obo:CHEBI_57630 a rdfs:Class ; rdfs:label "gamma-amino-beta-hydroxybutyric acid zwitterion" ; rdfs:comment "Zwitterionic form of gamma-amino-beta-hydroxybutyric acid having an anionic carboxy group and a protonated amino group." ; rdfs:subClassOf obo:CHEBI_35238 . obo:GO_0016477 a rdfs:Class ; rdfs:label "cell migration" ; rdfs:comment "The controlled self-propelled movement of a cell from one site to a destination guided by molecular cues. Cell migration is a central process in the development and maintenance of multicellular organisms." ; rdfs:subClassOf obo:GO_0048870 . obo:NCBITaxon_2801852 a rdfs:Class ; rdfs:label "Bat coronavirus RacCS224" ; rdfs:subClassOf obo:NCBITaxon_1986197 . obo:DRON_00877833 a rdfs:Class ; rdfs:label "selumetinib Oral Capsule" ; rdfs:subClassOf obo:DRON_00000026 . obo:CHEBI_25676 a rdfs:Class ; rdfs:label "oligopeptide" ; rdfs:comment "A peptide containing a relatively small number of amino acids." ; rdfs:subClassOf obo:CHEBI_16670 . obo:CIDO_0000181 a rdfs:Class ; rdfs:label "COVID-19 treatment with Remdesivir"@en ; rdfs:comment "The treatment of COVID-19 using Remdesivir, which has been approved by an Emergency Use Authorization (EUA) from the US FDA" ; rdfs:subClassOf obo:CIDO_0000186 . obo:CHEBI_52214 a rdfs:Class ; rdfs:label "ligand" ; rdfs:comment "Any molecule or ion capable of binding to a central metal atom to form coordination complexes." ; rdfs:subClassOf obo:CHEBI_51086 . obo:CHEBI_23114 a rdfs:Class ; rdfs:label "chloride salt" ; rdfs:subClassOf obo:CHEBI_23117 , obo:CHEBI_33958 . obo:CIDO_0000747 a rdfs:Class ; rdfs:label "P976L in SARS-CoV-2 pp1b protein"@en ; rdfs:comment "An AA variant that has mutated an pp1b amino acid at position 976 into leucine in pp1b." ; rdfs:subClassOf obo:CIDO_0001084 . obo:NCBITaxon_231514 a rdfs:Class ; rdfs:label "SARS coronavirus SZ13" ; rdfs:subClassOf obo:NCBITaxon_694009 . obo:CIDO_0000938 a rdfs:Class ; rdfs:label "SARS-CoV2 nsp8 protein binding to human MRPS5" ; rdfs:comment "SARS-CoV2 nsp8 protein binding to human MRPS5, as evidented by an affinity-purification mass spectrometry experiment" ; rdfs:subClassOf obo:CIDO_0000582 . obo:PR_000013868 a rdfs:Class ; rdfs:label "receptor expression-enhancing protein 6" ; rdfs:comment "A protein that is a translation product of the human REEP6 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:CIDO_0000062 a rdfs:Class ; rdfs:label "SARS-CoV-2 nsp1 protein interaction with host protein"@en ; rdfs:comment "A molecular interaction that has participant of the SARS-CoV-2 nsp1 protein and a host protein" ; rdfs:subClassOf obo:CIDO_0000348 . obo:NCBITaxon_422220 a rdfs:Class ; rdfs:label "Bovine coronavirus E-AH187" ; rdfs:subClassOf obo:NCBITaxon_11128 . obo:PR_P78356 a rdfs:Class ; rdfs:label "phosphatidylinositol 5-phosphate 4-kinase type-2 beta (human)" ; rdfs:comment "A phosphatidylinositol 5-phosphate 4-kinase type-2 beta that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000012742 , obo:PR_000029067 . obo:CHEBI_78840 a rdfs:Class ; rdfs:label "olefinic compound" ; rdfs:comment "Any organic molecular entity that contains at least one C=C bond." ; rdfs:subClassOf obo:CHEBI_50860 . obo:UBERON_0005177 a rdfs:Class ; rdfs:label "trunk region element" ; rdfs:comment "An organ or element that part of the trunk region. The trunk region can be further subdividied into thoracic (including chest and thoracic cavity) and abdominal (including abdomen and pelbis) regions." ; rdfs:subClassOf obo:UBERON_0000062 . obo:CHEBI_16236 a rdfs:Class ; rdfs:label "ethanol" ; rdfs:comment "A primary alcohol that is ethane in which one of the hydrogens is substituted by a hydroxy group." ; rdfs:subClassOf obo:CHEBI_134179 , obo:CHEBI_15734 , obo:CHEBI_23982 , obo:CHEBI_50584 . obo:HP_0004749 a rdfs:Class ; rdfs:label "Atrial flutter" ; rdfs:comment "A type of atrial arrhythmia characterized by atrial rates of between 240 and 400 beats per minute and some degree of atrioventricular node conduction block. Typically, the ventricular rate is half the atrial rate. In the EKG; atrial flutter waves are observed as sawtooth-like atrial activity. Pathophysiologically, atrial flutter is a form of atrial reentry in which there is a premature electrical impulse creates a self-propagating circuit." ; rdfs:subClassOf obo:HP_0001692 . obo:CHEBI_77035 a rdfs:Class ; rdfs:label "expectorant" ; rdfs:comment "Compounds that are considered to increase the volume of secretions in the respiratory tract, so facilitating their removal by ciliary action and coughing. Compare with mucolytics, which decrease the viscosity of mucus, facilitating its removal by ciliary action and expectoration, and antitussives, which suppress the cough reflex." ; rdfs:subClassOf obo:CHEBI_23888 . obo:NCBITaxon_572288 a rdfs:Class ; rdfs:label "Bulbul coronavirus HKU11-934" ; rdfs:subClassOf obo:NCBITaxon_574549 . a rdfs:Class ; rdfs:label "Serotonin Antagonists [MoA]" ; rdfs:subClassOf . obo:DRON_00018264 a rdfs:Class ; rdfs:label "omacetaxine mepesuccinate" ; rdfs:subClassOf obo:OBI_0000047 . obo:CIDO_0020135 a rdfs:Class ; rdfs:label "Everlywell COVID-19 Test Home Collection Kit DTC" ; rdfs:seeAlso ; rdfs:subClassOf obo:CIDO_0000455 . obo:CHEBI_46777 a rdfs:Class ; rdfs:label "monohydroxypyrrolidine" ; rdfs:subClassOf obo:CHEBI_46773 . obo:NCBITaxon_227860 a rdfs:Class ; rdfs:label "SARS coronavirus Vietnam" ; rdfs:subClassOf obo:NCBITaxon_694009 . obo:NCBITaxon_2042544 a rdfs:Class ; rdfs:label "Coronavirus PREDICT CoV-18" ; rdfs:subClassOf obo:NCBITaxon_366617 . obo:NCBITaxon_1429857 a rdfs:Class ; rdfs:label "Betacoronavirus Pipistrellus kuhlii/Italy/206645-29/2011" ; rdfs:subClassOf obo:NCBITaxon_696098 . obo:PR_000007174 a rdfs:Class ; rdfs:label "endoplasmic reticulum-Golgi intermediate compartment protein 1" ; rdfs:comment "A protein that is a translation product of the human ERGIC1 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:HP_0005115 a rdfs:Class ; rdfs:label "Supraventricular arrhythmia" ; rdfs:comment "A type of arrhythmia that originates above the ventricles, whereby the electrical impulse propagates down the normal His Purkinje system similar to normal sinus rhythm." ; rdfs:subClassOf obo:HP_0011675 . obo:OPMI_0000569 a rdfs:Class ; rdfs:label "drug exposure stop reason specification"@en ; rdfs:comment "The reason a person stopped a medication as it is represented in the source. Reasons include regimen completed, changed, removed, etc." ; rdfs:subClassOf obo:IAO_0000007 . obo:CHEBI_14321 a rdfs:Class ; rdfs:label "glutamate(1-)" ; rdfs:comment "An alpha-amino-acid anion that is the conjugate base of glutamic acid, having anionic carboxy groups and a cationic amino group" ; rdfs:subClassOf obo:CHEBI_33558 . obo:CHEBI_38686 a rdfs:Class ; rdfs:label "dihydroxyflavone" ; rdfs:comment "Any hydroxyflavone in which two ring hydrogens are replaced by hydroxy substituents." ; rdfs:subClassOf obo:CHEBI_24698 . obo:PR_000001900 a rdfs:Class ; rdfs:label "neuropilin-1" ; rdfs:comment "A protein that is a translation product of the human NRP1 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:NCBITaxon_1696542 a rdfs:Class ; rdfs:label "Alphacoronavirus Pip2_Cr_FR_2014" ; rdfs:subClassOf obo:NCBITaxon_366617 . obo:NCBITaxon_389159 a rdfs:Class ; rdfs:label "Bat coronavirus (BtCoV/A910/2005)" ; rdfs:subClassOf obo:NCBITaxon_389126 . obo:NCBITaxon_1329950 a rdfs:Class ; rdfs:label "Unidentata" ; rdfs:subClassOf obo:NCBITaxon_1329961 . obo:CIDO_0000084 a rdfs:Class ; rdfs:label "host-coronavirus interaction"@en ; rdfs:comment "A process that involves the interaction between the coronavirus and its host" ; rdfs:subClassOf obo:BFO_0000015 . obo:CHEBI_32623 a rdfs:Class ; rdfs:label "D-leucinate" ; rdfs:comment "The D-enantiomer of leucinate." ; rdfs:subClassOf obo:CHEBI_32627 . obo:CHEBI_75600 a rdfs:Class ; rdfs:label "EC 6.3.* (C-N bond-forming ligase) inhibitor" ; rdfs:comment "A ligase inhibitor that interferes with the action of a C-N bond-forming ligase (EC 6.3.*.*)." ; rdfs:subClassOf obo:CHEBI_75603 . obo:CIDO_0000781 a rdfs:Class ; rdfs:label "SARS-CoV2 N protein binding to human G3BP2" ; rdfs:comment "SARS-CoV2 N protein binding to human G3BP2, as evidented by an affinity-purification mass spectrometry experiment" ; rdfs:subClassOf obo:CIDO_0000056 . obo:GO_0048148 a rdfs:Class ; rdfs:label "behavioral response to cocaine" ; rdfs:comment "Any process that results in a change in the behavior of an organism as a result of a cocaine stimulus." ; rdfs:subClassOf obo:GO_0030534 . obo:GO_0008150 a rdfs:Class ; rdfs:label "biological_process" ; rdfs:comment "A biological process represents a specific objective that the organism is genetically programmed to achieve. Biological processes are often described by their outcome or ending state, e.g., the biological process of cell division results in the creation of two daughter cells (a divided cell) from a single parent cell. A biological process is accomplished by a particular set of molecular functions carried out by specific gene products (or macromolecular complexes), often in a highly regulated manner and in a particular temporal sequence." ; rdfs:subClassOf obo:BFO_0000015 . a rdfs:Class ; rdfs:label "NILOTINIB" ; rdfs:subClassOf . a rdfs:Class ; rdfs:label "Rhinitis [Disease/Finding]" ; rdfs:subClassOf , . obo:PR_000010141 a rdfs:Class ; rdfs:label "mitogen-activated protein kinase kinase kinase 9" ; rdfs:comment "A protein that is a translation product of the human MAP3K9 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:NCBITaxon_9682 a rdfs:Class ; rdfs:label "Felis" ; rdfs:subClassOf obo:NCBITaxon_338152 . obo:CHEBI_27561 a rdfs:Class ; rdfs:label "oxirane" ; rdfs:comment "A saturated organic heteromonocyclic parent that is a three-membered heterocycle of two carbon atoms and one oxygen atom." ; rdfs:subClassOf obo:CHEBI_138675 , obo:CHEBI_36389 , obo:CHEBI_38104 . obo:NCBITaxon_864607 a rdfs:Class ; rdfs:label "Bat coronavirus BNM98-29/BGR/2008" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:CIDO_0001021 a rdfs:Class ; rdfs:label "Alunacedase alfa" ; rdfs:subClassOf obo:CHEBI_23367 . obo:CIDO_0000455 a rdfs:Class ; rdfs:label "FDA EUA authorized COVID-19 diagnostic home collection kit"@en ; rdfs:subClassOf obo:CIDO_0000454 . obo:GO_0050865 a rdfs:Class ; rdfs:label "regulation of cell activation" ; rdfs:comment "Any process that modulates the frequency, rate or extent of cell activation, the change in the morphology or behavior of a cell resulting from exposure to an activating factor such as a cellular or soluble ligand." ; rdfs:subClassOf obo:GO_0050794 . obo:NCBITaxon_389245 a rdfs:Class ; rdfs:label "Bat coronavirus (BtCoV/A1116/2005)" ; rdfs:subClassOf obo:NCBITaxon_389126 . obo:CIDO_0001039 a rdfs:Class ; rdfs:label "SARS-CoV2 orf9b protein binding to human MARK2" ; rdfs:comment "SARS-CoV2 orf9b protein binding to human MARK2, as evidented by an affinity-purification mass spectrometry experiment" ; rdfs:subClassOf obo:CIDO_0000052 . obo:NCBITaxon_903582 a rdfs:Class ; rdfs:label "Kenya bat coronavirus BtKY44" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:CIDO_0000668 a rdfs:Class ; rdfs:label "E484K in SARS-CoV-2 S protein" ; rdfs:comment "An AA mutation or AA variant that has mutated an amino acid at position 484 into a lysine in S protein." ; rdfs:subClassOf obo:CIDO_0000593 . obo:VO_0005248 a rdfs:Class ; rdfs:label "COVID-19 subunit vaccine by National Vaccine and Serum Institute of China"@en ; rdfs:comment "A SARS-CoV-2 subunit vaccine developed by the National Vaccine and Serum Institute of China" ; rdfs:subClassOf obo:VO_0005202 . obo:CHEBI_28659 a rdfs:Class ; rdfs:label "phosphorus atom" ; rdfs:subClassOf obo:CHEBI_25585 , obo:CHEBI_33300 . obo:CHEBI_64708 a rdfs:Class ; rdfs:label "one-carbon compound" ; rdfs:comment "An organic molecular entity containing a single carbon atom (C1)." ; rdfs:subClassOf obo:CHEBI_50860 . a rdfs:Class ; rdfs:label "Breast Neoplasms [Disease/Finding]" ; rdfs:subClassOf , . obo:CHEBI_32505 a rdfs:Class ; rdfs:label "phenylalaninium" ; rdfs:comment "An alpha-amino-acid cation that is the conjugate acid of phenylalanine, arising from protonation of the amino group." ; rdfs:subClassOf obo:CHEBI_33719 . obo:NCBITaxon_1261611 a rdfs:Class ; rdfs:label "Miniopterus bat coronavirus/South Africa/Irene/2009" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:PR_000011131 a rdfs:Class ; rdfs:label "serine/threonine-protein kinase Nek5" ; rdfs:comment "A protein that is a translation product of the human NEK5 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:VO_0005114 a rdfs:Class ; rdfs:label "β-propiolactone-inactivated SARS-CoV vaccine" ; rdfs:comment "A SARS inactivated vaccine made from whole killed (inactivated by beta-propiolactone) SARS-CoV" ; rdfs:subClassOf obo:VO_0012183 . obo:VO_0004907 a rdfs:Class ; rdfs:label "MERS-CoV S protein"@en ; rdfs:subClassOf obo:VO_0004906 . obo:NCBITaxon_864593 a rdfs:Class ; rdfs:label "Bat coronavirus BB98-43/BGR/2008" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:CHEBI_50996 a rdfs:Class ; rdfs:label "tertiary amino compound" ; rdfs:comment "A compound formally derived from ammonia by replacing three hydrogen atoms by organyl groups." ; rdfs:subClassOf obo:CHEBI_50047 . obo:PR_P45984 a rdfs:Class ; rdfs:label "mitogen-activated protein kinase 9 (human)" ; rdfs:comment "A mitogen-activated protein kinase 9 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000010163 , obo:PR_000029067 . obo:PR_Q96S52 a rdfs:Class ; rdfs:label "GPI transamidase component PIG-S (human)" ; rdfs:comment "A GPI transamidase component PIG-S that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000012706 , obo:PR_000029067 . a rdfs:Class ; rdfs:label "Acids, Acyclic [Chemical/Ingredient]" ; rdfs:subClassOf . obo:OPMI_0000480 a rdfs:Class ; rdfs:label "care site identifier"@en ; rdfs:comment "A centrally registered identifier that refers to where the care provider typically provides the primary care." ; rdfs:subClassOf obo:IAO_0000578 . obo:PR_P12318 a rdfs:Class ; rdfs:label "low affinity immunoglobulin gamma Fc region receptor II-a (human)" ; rdfs:comment "A low affinity immunoglobulin gamma Fc region receptor II-a that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000001480 , obo:PR_000029067 . obo:VO_0005102 a rdfs:Class ; rdfs:label "SARS M protein DNA vaccine" ; rdfs:comment "'A SARS DNA vaccine that is made from recombinant plasmid containing membrane protein (M) sequence constructed then expressed and purified from E. coli bacteria’" ; rdfs:subClassOf obo:VO_0012183 . obo:CIDO_0000228 a rdfs:Class ; rdfs:label "receptor role"@en ; rdfs:subClassOf obo:BFO_0000023 . a rdfs:Class ; rdfs:label "Triazolam [Chemical/Ingredient]" ; rdfs:subClassOf . obo:CHEBI_37931 a rdfs:Class ; rdfs:label "10H-phenothiazine" ; rdfs:comment "The 10H-tautomer of phenothiazine." ; rdfs:subClassOf obo:CHEBI_37932 . a rdfs:Class ; rdfs:label "dalbavancin [Chemical/Ingredient]" ; rdfs:subClassOf . obo:OGG_3000003627 a rdfs:Class ; rdfs:label "CXCL10" ; rdfs:comment "Other designations: 10 kDa interferon gamma-induced protein|C-X-C motif chemokine 10|gamma IP10|gamma-IP10|interferon-inducible cytokine IP-10|protein 10 from interferon (gamma)-induced cell line|small inducible cytokine subfamily B (Cys-X-Cys), member 10|small-inducible cytokine B10" ; rdfs:subClassOf obo:OGG_2060009606 . obo:CIDO_0000073 a rdfs:Class ; rdfs:label "chemical role against SARS-CoV-2 replication"@en ; rdfs:subClassOf obo:CIDO_0000072 . obo:NCBITaxon_249073 a rdfs:Class ; rdfs:label "SARS coronavirus JMD" ; rdfs:subClassOf obo:NCBITaxon_694009 . obo:CIDO_0000700 a rdfs:Class ; rdfs:label "T478K in SARS-CoV-2 S protein" ; rdfs:comment "An AA mutation or AA variant that has mutated an amino acid at position 478 into a lysine in S protein." ; rdfs:subClassOf obo:CIDO_0001157 . obo:NCBITaxon_698419 a rdfs:Class ; rdfs:label "SARS coronavirus wtic-MB" ; rdfs:subClassOf obo:NCBITaxon_698398 . obo:CHEBI_27267 a rdfs:Class ; rdfs:label "valine derivative" ; rdfs:comment "An amino acid derivative resulting from reaction of valine at the amino group or the carboxy group, or from the replacement of any hydrogen of valine by a heteroatom. The definition normally excludes peptides containing valine residues." ; rdfs:subClassOf obo:CHEBI_25359 , obo:CHEBI_83821 . obo:GO_1903901 a rdfs:Class ; rdfs:label "negative regulation of viral life cycle" ; rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of viral life cycle." ; rdfs:subClassOf obo:GO_0048525 , obo:GO_1903900 . obo:PR_000003282 a rdfs:Class ; rdfs:label "dual specificity mitogen-activated protein kinase kinase 6" ; rdfs:comment "A dual specificity mitogen-activated protein kinase kinase 3/6 that is a translation product of the human MAP2K6 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000021990 . obo:CHEBI_78444 a rdfs:Class ; rdfs:label "EC 3.1.1.1 (carboxylesterase) inhibitor" ; rdfs:comment "Any EC 3.1.1.* (carboxylic ester hydrolase) inhibitor that inhibits the action of carboxylesterase (EC 3.1.1.1 )." ; rdfs:subClassOf obo:CHEBI_76773 . obo:CHEBI_27358 a rdfs:Class ; rdfs:label "yohimban alkaloid" ; rdfs:subClassOf obo:CHEBI_38958 , obo:CHEBI_65323 . obo:OBI_0000838 a rdfs:Class ; rdfs:label "material maintenance" ; rdfs:comment "a process with that achieves the objective to maintain some or all of the characteristics of an input material over time" ; rdfs:subClassOf obo:OBI_0000011 . obo:CHEBI_76737 a rdfs:Class ; rdfs:label "EC 1.10.* (oxidoreductase acting on diphenols and related substances as donors) inhibitor" ; rdfs:comment "An oxidoreductase inhibitor which interferes with the action of an oxidoreductase acting on diphenols and related substances as donors (EC 1.10.*.*)." ; rdfs:subClassOf obo:CHEBI_76725 . obo:PATO_0001237 a rdfs:Class ; rdfs:label "quality of a single physical entity"@en ; rdfs:comment "A physical object quality which inheres in a single-bearer."@en ; rdfs:subClassOf obo:PATO_0001241 . obo:VO_0005183 a rdfs:Class ; rdfs:label "CORVax12"@en ; rdfs:comment "A SARS-CoV-2 DNA vaccine developed by Providence Health & Services." ; rdfs:subClassOf obo:VO_0005203 . obo:NCBITaxon_1699341 a rdfs:Class ; rdfs:label "Myotis Bat Alphacoronavirus strain YNXY_46C" ; rdfs:subClassOf obo:NCBITaxon_366617 . obo:PR_000012716 a rdfs:Class ; rdfs:label "phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta" ; rdfs:comment "A protein that is a translation product of the human PIK3C2B gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:NCBITaxon_931910 a rdfs:Class ; rdfs:label "Alphacoronavirus Eptesicus fuscus/Appalachian Ridge/P1-66604/IT/USA/2009" ; rdfs:subClassOf obo:NCBITaxon_366617 . obo:CIDO_0001218 a rdfs:Class ; rdfs:label "Multiple Real-Time PCR Kit for Detection of 2019-nCoV. (Wuhan Easy Diagnosis Biomedicine Co., Ltd.)" ; rdfs:comment "Manufacturor: Wuhan Easy Diagnosis Biomedicine Co., Ltd. 武汉明德生物科技股份有限公司" ; rdfs:subClassOf obo:CIDO_0000021 . obo:CHEBI_30106 a rdfs:Class ; rdfs:label "azo group" ; rdfs:subClassOf obo:CHEBI_33246 . obo:CIDO_0000770 a rdfs:Class ; rdfs:label "SARS-CoV2 M protein binding to human SLC30A9" ; rdfs:comment "SARS-CoV2 M protein binding to human SLC30A9, as evidented by an affinity-purification mass spectrometry experiment" ; rdfs:subClassOf obo:CIDO_0000055 . obo:CHEBI_16150 a rdfs:Class ; rdfs:label "benzoate" ; rdfs:comment "The simplest member of the class of benzoates that is the conjugate base of benzoic acid, comprising a benzoic acid core with a proton missing to give a charge of -1." ; rdfs:subClassOf obo:CHEBI_22718 . obo:CHEBI_48379 a rdfs:Class ; rdfs:label "isourea" ; rdfs:comment "A carboximidic acid that is the imidic acid tautomer of urea, H2NC(=NH)OH, and its hydrocarbyl derivatives." ; rdfs:subClassOf obo:CHEBI_48378 . obo:GO_0042575 a rdfs:Class ; rdfs:label "DNA polymerase complex" ; rdfs:comment "A protein complex that possesses DNA polymerase activity and is involved in template directed synthesis of DNA." ; rdfs:subClassOf obo:GO_0032991 , obo:OBI_0000427 . obo:CHEBI_59869 a rdfs:Class ; rdfs:label "L-alpha-amino acid zwitterion" ; rdfs:comment "Zwitterionic form of an L-alpha-amino acid having an anionic carboxy group and a protonated amino group." ; rdfs:subClassOf obo:CHEBI_78608 . obo:CIDO_0000877 a rdfs:Class ; rdfs:label "SARS-CoV2 nsp4 protein binding to human DNAJC11" ; rdfs:comment "SARS-CoV2 nsp4 protein binding to human DNAJC11, as evidented by an affinity-purification mass spectrometry experiment" ; rdfs:subClassOf obo:CIDO_0000581 . obo:HP_0001695 a rdfs:Class ; rdfs:label "Cardiac arrest" ; rdfs:comment "An abrupt loss of heart function." ; rdfs:subClassOf obo:HP_0011675 . obo:NCBITaxon_1329961 a rdfs:Class ; rdfs:label "Bifurcata" ; rdfs:subClassOf obo:NCBITaxon_8509 . obo:GO_0035820 a rdfs:Class ; rdfs:label "negative regulation of renal sodium excretion by angiotensin" ; rdfs:comment "The process in which angiotensin decreases the amount of sodium that is excreted in urine over a unit of time." ; rdfs:subClassOf obo:GO_0003083 , obo:GO_0035814 . obo:CHEBI_3638 a rdfs:Class ; rdfs:label "Chloroquine" ; rdfs:comment "An aminoquinoline that is quinoline which is substituted at position 4 by a [5-(diethylamino)pentan-2-yl]amino group at at position 7 by chlorine. It is used for the treatment of malaria, hepatic amoebiasis, lupus erythematosus, light-sensitive skin eruptions, and rheumatoid arthritis." ; rdfs:subClassOf obo:CHEBI_26509 , obo:CHEBI_36683 , obo:CHEBI_36709 , obo:CHEBI_50995 , obo:CHEBI_50996 . obo:CHEBI_52640 a rdfs:Class ; rdfs:label "N-acylethanolamine" ; rdfs:comment "An ethanolamine substituted at nitrogen by an acyl group." ; rdfs:subClassOf obo:CHEBI_15734 , obo:CHEBI_23981 . obo:GO_0055065 a rdfs:Class ; rdfs:label "metal ion homeostasis" ; rdfs:comment "Any process involved in the maintenance of an internal steady state of metal ions within an organism or cell." ; rdfs:subClassOf obo:GO_0055080 , obo:GO_0098771 . obo:CHEBI_32832 a rdfs:Class ; rdfs:label "threoninate" ; rdfs:subClassOf obo:CHEBI_33558 . obo:CIDO_0000741 a rdfs:Class ; rdfs:label "R246N in SARS-CoV-2 S protein"@en ; rdfs:comment "An AA mutation or AA variant that has mutated an amino acid at position 452 into aspargine in S protein." ; rdfs:subClassOf obo:CIDO_0000593 . obo:PR_000001467 a rdfs:Class ; rdfs:label "intercellular adhesion molecule 1" ; rdfs:comment "An intercellular adhesion molecule 1/3 that is a translation product of the human ICAM1 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000001357 . obo:CIDO_0000913 a rdfs:Class ; rdfs:label "SARS-CoV2 nsp7 protein binding to human RAB2A" ; rdfs:comment "SARS-CoV2 nsp7 protein binding to human RAB2A, as evidented by an affinity-purification mass spectrometry experiment" ; rdfs:subClassOf obo:CIDO_0000049 . obo:CHEBI_64382 a rdfs:Class ; rdfs:label "organosulfonate salt" ; rdfs:comment "Any organic salt prepared using an organosulfonic acid as the acid component." ; rdfs:subClassOf obo:CHEBI_24868 , obo:CHEBI_33261 . obo:NCBITaxon_497949 a rdfs:Class ; rdfs:label "Bat coronavirus M.dau/Germany/D8.42/2007" ; rdfs:subClassOf obo:NCBITaxon_366617 . obo:NCBITaxon_931899 a rdfs:Class ; rdfs:label "Alphacoronavirus Eptesicus fuscus/Appalachian Ridge/P1-C454/IT/USA/2009" ; rdfs:subClassOf obo:NCBITaxon_366617 . obo:OBI_0000977 a rdfs:Class ; rdfs:label "paraffin storage" ; rdfs:comment "a storage process with input organism or anatomical entity and paraffin and output material embedded in paraffin for long term storage" ; rdfs:subClassOf obo:OBI_0302893 . obo:GO_0000184 a rdfs:Class ; rdfs:label "nuclear-transcribed mRNA catabolic process, nonsense-mediated decay" ; rdfs:comment "The nonsense-mediated decay pathway for nuclear-transcribed mRNAs degrades mRNAs in which an amino-acid codon has changed to a nonsense codon; this prevents the translation of such mRNAs into truncated, and potentially harmful, proteins." ; rdfs:subClassOf obo:GO_0006402 . obo:GO_0072599 a rdfs:Class ; rdfs:label "establishment of protein localization to endoplasmic reticulum" ; rdfs:comment "The directed movement of a protein to a specific location in the endoplasmic reticulum." ; rdfs:subClassOf obo:GO_0033365 , obo:GO_0072594 . obo:PR_P22309 a rdfs:Class ; rdfs:label "UDP-glucuronosyltransferase 1A1 (human)" ; rdfs:comment "A UDP-glucuronosyltransferase 1A1 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000017048 , obo:PR_000029067 . obo:NCBITaxon_502107 a rdfs:Class ; rdfs:label "Murine coronavirus RA59/SJHM" ; rdfs:subClassOf obo:NCBITaxon_11138 . obo:PR_Q9UL15 a rdfs:Class ; rdfs:label "BAG family molecular chaperone regulator 5 (human)" ; rdfs:comment "A BAG family molecular chaperone regulator 5 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000004623 , obo:PR_000029067 . obo:PR_Q9UHD2 a rdfs:Class ; rdfs:label "serine/threonine-protein kinase TBK1 (human)" ; rdfs:comment "A serine/threonine-protein kinase TBK1 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000001779 , obo:PR_000029067 . obo:GO_0014066 a rdfs:Class ; rdfs:label "regulation of phosphatidylinositol 3-kinase signaling" ; rdfs:comment "Any process that modulates the frequency, rate or extent of signal transduction mediated by the phosphatidylinositol 3-kinase cascade." ; rdfs:subClassOf obo:GO_1902531 . obo:CIDO_0000994 a rdfs:Class ; rdfs:label "SARS-CoV2 orf8 protein binding to human EMC1" ; rdfs:comment "SARS-CoV2 orf8 protein binding to human EMC1, as evidented by an affinity-purification mass spectrometry experiment" ; rdfs:subClassOf obo:CIDO_0000051 . obo:HP_0000707 a rdfs:Class ; rdfs:label "Abnormality of the nervous system" ; rdfs:comment "An abnormality of the nervous system." ; rdfs:subClassOf obo:HP_0000118 . obo:CHEBI_20156 a rdfs:Class ; rdfs:label "3-oxo-Delta(1) steroid" ; rdfs:comment "Any 3-oxo steroid that contains a double bond between positions 1 and 2." ; rdfs:subClassOf obo:CHEBI_47788 , obo:CHEBI_51689 . obo:PATO_0001422 a rdfs:Class ; rdfs:label "dead" ; rdfs:comment "A viability quality inhering in a bearer by virtue of the cessation of the bearer's life." ; rdfs:subClassOf obo:PATO_0000169 . obo:NCBITaxon_745740 a rdfs:Class ; rdfs:label "Coronavirus M.das/VM2/2007/NLD" ; rdfs:subClassOf obo:NCBITaxon_696098 . obo:NCBITaxon_903571 a rdfs:Class ; rdfs:label "Kenya bat coronavirus BtKY103" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:PR_P25774 a rdfs:Class ; rdfs:label "cathepsin S (human)" ; rdfs:comment "A cathepsin S that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000006033 , obo:PR_000029067 . obo:NCBITaxon_2732408 a rdfs:Class ; rdfs:label "Pisuviricota" ; rdfs:subClassOf obo:NCBITaxon_2732396 . obo:PR_Q8NG66 a rdfs:Class ; rdfs:label "serine/threonine-protein kinase Nek11 (human)" ; rdfs:comment "A serine/threonine-protein kinase Nek11 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000011127 , obo:PR_000029067 . obo:CIDO_0000192 a rdfs:Class ; rdfs:label "host assembly of SARS-CoV-2 virion"@en ; rdfs:subClassOf obo:CIDO_0000116 . obo:RO_0002234 a rdf:Property ; rdfs:label "has output"@en ; rdfs:comment "p has output c iff c is a participant in p, c is present at the end of p, and c is not present in the same state at the beginning of p." ; rdfs:range . obo:NCBITaxon_9974 a rdfs:Class ; rdfs:label "Manis javanica" ; rdfs:subClassOf obo:NCBITaxon_9973 . obo:PR_000016770 a rdfs:Class ; rdfs:label "testis-specific serine/threonine-protein kinase 1" ; rdfs:comment "A protein that is a translation product of the human TSSK1B gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:PR_000006453 a rdfs:Class ; rdfs:label "Delta(24)-sterol reductase" ; rdfs:comment "A protein that is a translation product of the human DHCR24 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:CIDO_0000805 a rdfs:Class ; rdfs:label "SARS-CoV2 nsp12 protein binding to human CRTC3" ; rdfs:comment "SARS-CoV2 nsp12 protein binding to human CRTC3, as evidented by an affinity-purification mass spectrometry experiment" ; rdfs:subClassOf obo:CIDO_0000057 . obo:PR_000005354 a rdfs:Class ; rdfs:label "centrosomal protein of 68 kDa" ; rdfs:comment "A protein that is a translation product of the human CEP68 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:CHEBI_60258 a rdfs:Class ; rdfs:label "EC 3.4.* (hydrolases acting on peptide bond) inhibitor" ; rdfs:comment "A hydrolase inhibitor that interferes with the action of any hydrolase acting on peptide bonds (peptidase), EC 3.4.*.*)." ; rdfs:subClassOf obo:CHEBI_76759 . obo:NCBITaxon_264374 a rdfs:Class ; rdfs:label "SARS coronavirus TW-HP4" ; rdfs:subClassOf obo:NCBITaxon_264370 . obo:NCBITaxon_9627 a rdfs:Class ; rdfs:label "Vulpes vulpes" ; rdfs:subClassOf obo:NCBITaxon_9625 . obo:DOID_0060672 a rdfs:Class ; rdfs:label "Grn-related frontotemporal lobar degeneration with Tdp43 inclusions" ; rdfs:comment "A frontotemporal dementia characterized by variable phenotypic expression typically including social, behavioral, or language deterioration, rather than memory or motor deficits and the presence of TARDBP-positive inclusions that has_material_basis_in mutation in the GRN gene on chromosome 17q21.31." ; rdfs:subClassOf obo:DOID_0050736 , obo:DOID_9255 . obo:NCBITaxon_1696543 a rdfs:Class ; rdfs:label "Alphacoronavirus Pip3_M_FR_2014" ; rdfs:subClassOf obo:NCBITaxon_366617 . obo:CHEBI_27171 a rdfs:Class ; rdfs:label "organic heterobicyclic compound" ; rdfs:subClassOf obo:CHEBI_24532 , obo:CHEBI_33672 , obo:CHEBI_38166 . obo:GO_0034220 a rdfs:Class ; rdfs:label "ion transmembrane transport" ; rdfs:comment "A process in which an ion is transported across a membrane." ; rdfs:subClassOf obo:GO_0006811 , obo:GO_0055085 . obo:CIDO_0000412 a rdfs:Class ; rdfs:label "susceptibility to biological up-regulation"@en ; rdfs:comment "A disposition that a material entity such as a gene or protein is susceptible to be up-regulated" ; rdfs:subClassOf obo:CIDO_0000416 . obo:CHEBI_35391 a rdfs:Class ; rdfs:label "aspartate(1-)" ; rdfs:comment "An alpha-amino-acid anion that is the conjugate base of aspartic acid." ; rdfs:subClassOf obo:CHEBI_132943 . obo:CIDO_0000931 a rdfs:Class ; rdfs:label "SARS-CoV2 nsp8 protein binding to human HECTD1" ; rdfs:comment "SARS-CoV2 nsp8 protein binding to human HECTD1, as evidented by an affinity-purification mass spectrometry experiment" ; rdfs:subClassOf obo:CIDO_0000582 . obo:NCBITaxon_230235 a rdfs:Class ; rdfs:label "Bovine coronavirus G95" ; rdfs:subClassOf obo:NCBITaxon_11128 . obo:NCBITaxon_1697925 a rdfs:Class ; rdfs:label "Deltacoronavirus B07" ; rdfs:subClassOf obo:NCBITaxon_1232736 . obo:NCBITaxon_1897067 a rdfs:Class ; rdfs:label "Bat coronavirus Art.lit/1816/BRA/2010" ; rdfs:subClassOf obo:NCBITaxon_366617 . obo:PR_000000682 a rdfs:Class ; rdfs:label "voltage-gated potassium channel alpha subunit with PAS domain" ; rdfs:comment "A voltage-gated potassium channel protein that has amino- and carboxyl-terminal intracellular domains separated by a domain (common with other ion channels) containing six transmembrane helices (S1-S6) in which the last two helices (S5 and S6) flank a loop, called the pore loop, which determines ion selectivity. Unique to this class is the presence of an N-terminal PAS fold domain (Pfam:PF00989). In addition, in the cytoplasmic region downstream from S6, there is a segment that shares substantial similarity to the Cyclic nucleotide-binding domain (Pfam:PF00027) (CNBD) present in cyclic nucleotide-gated cation channel subunits (PR:000000674 and PR:000000674). These channels regulate membrane excitability." ; rdfs:subClassOf obo:PR_000044654 . obo:CIDO_0000162 a rdfs:Class ; rdfs:label "respirtoary droplet transmission of SARS-CoV-2"@en ; rdfs:subClassOf obo:CIDO_0000161 . obo:CHEBI_60643 a rdfs:Class ; rdfs:label "NMDA receptor antagonist" ; rdfs:comment "Any substance that inhibits the action of N-methyl-D-aspartate (NMDA) receptors. They tend to induce a state known as dissociative anesthesia, marked by catalepsy, amnesia, and analgesia, while side effects can include hallucinations, nightmares, and confusion. Due to their psychotomimetic effects, many NMDA receptor antagonists are used as recreational drugs." ; rdfs:subClassOf obo:CHEBI_60798 . obo:NCBITaxon_643397 a rdfs:Class ; rdfs:label "Coronavirus Anas/p71/2005/GBR" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:VO_0005103 a rdfs:Class ; rdfs:label "Salmonella-CTLA4-S SARS DNA vaccine" ; rdfs:comment "'A SARS DNA vaccine that is made from oral live-attenuated auxotrophic S. typhimurium aroA strain SL7207 that contained CTLA4HingeSARS800 with SARS-CoV S protein‘" ; rdfs:subClassOf obo:VO_0012183 . obo:VO_0005194 a rdfs:Class ; rdfs:label "COVAC"@en ; rdfs:comment "A SARS-CoV-2 subunit vaccine with the S1 component of the SARS-CoV-2 spike (S) protein and SWE adjuvant." ; rdfs:subClassOf obo:VO_0005202 . a rdfs:Class ; rdfs:label "Lovastatin [Chemical/Ingredient]" ; rdfs:subClassOf . obo:NCBITaxon_305401 a rdfs:Class ; rdfs:label "SARS coronavirus A001" ; rdfs:subClassOf obo:NCBITaxon_694009 . obo:NCBITaxon_1429852 a rdfs:Class ; rdfs:label "Alphacoronavirus Pipistrellus kuhlii/Italy/206645-41/2010" ; rdfs:subClassOf obo:NCBITaxon_366617 . a rdfs:Class ; rdfs:label "Vomiting [Disease/Finding]" ; rdfs:subClassOf . obo:CHEBI_36141 a rdfs:Class ; rdfs:label "quinone" ; rdfs:comment "Compounds having a fully conjugated cyclic dione structure, such as that of benzoquinones, derived from aromatic compounds by conversion of an even number of -CH= groups into -C(=O)- groups with any necessary rearrangement of double bonds (polycyclic and heterocyclic analogues are included)." ; rdfs:subClassOf obo:CHEBI_3992 . a rdfs:Class ; rdfs:label "ANIDULAFUNGIN" ; rdfs:subClassOf . a rdfs:Class ; rdfs:label "Glycopeptides [Chemical/Ingredient]" ; rdfs:subClassOf , . obo:GO_0003674 a rdfs:Class ; rdfs:label "molecular_function" ; rdfs:comment "A molecular process that can be carried out by the action of a single macromolecular machine, usually via direct physical interactions with other molecular entities. Function in this sense denotes an action, or activity, that a gene product (or a complex) performs. These actions are described from two distinct but related perspectives: (1) biochemical activity, and (2) role as a component in a larger system/process." ; rdfs:subClassOf obo:BFO_0000015 . obo:VO_0005154 a rdfs:Class ; rdfs:label "SARS-CoV pCI-N DNA vaccine"@en ; rdfs:comment "A plasmid pCI-N, encoding the full-length N gene of SARS-CoV, was constructed and expressed in Escherichia coli DH5alpha" ; rdfs:subClassOf obo:VO_0012183 . obo:VariO_0014 a rdfs:Class ; rdfs:label "amino acid deletion" ; rdfs:comment "Removal of one or more continuous amino acids from protein." ; rdfs:subClassOf obo:VariO_0325 . obo:NCBITaxon_502096 a rdfs:Class ; rdfs:label "Waterbuck coronavirus US/OH-WD358-GnC/1994" ; rdfs:subClassOf obo:NCBITaxon_11128 . a rdfs:Class ; rdfs:label "Immunologically Active Molecule Production Alteration [PE]" ; rdfs:subClassOf . obo:PR_P0DTD1-1 a rdfs:Class ; rdfs:label "replicase polyprotein 1ab (SARS-CoV-2)" ; rdfs:comment "A rep gene translation product (SARS-CoV-2) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P0DTD1-1. Requires ribosomal frameshifting." ; rdfs:subClassOf obo:PR_000050263 . a rdfs:Class ; rdfs:label "Female Reproductive System Activity Alteration [PE]" ; rdfs:subClassOf . obo:CIDO_0020109 a rdfs:Class ; rdfs:label "Curative-Korva SARS-Cov-2 Assay" ; rdfs:seeAlso ; rdfs:subClassOf obo:CIDO_0000454 . obo:CIDO_0000924 a rdfs:Class ; rdfs:label "SARS-CoV2 nsp8 protein binding to human ATE1" ; rdfs:comment "SARS-CoV2 nsp8 protein binding to human ATE1, as evidented by an affinity-purification mass spectrometry experiment" ; rdfs:subClassOf obo:CIDO_0000582 . obo:NCBITaxon_1913642 a rdfs:Class ; rdfs:label "Mink coronavirus 1" ; rdfs:subClassOf obo:NCBITaxon_2509496 . obo:PR_P61106 a rdfs:Class ; rdfs:label "Ras-related protein Rab-14 (human)" ; rdfs:comment "A Ras-related protein Rab-14 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000013586 , obo:PR_000029067 . obo:CHEBI_22221 a rdfs:Class ; rdfs:label "acyl group" ; rdfs:comment "An organic group formed by removing one or more hydroxy groups from an oxoacid that has the general structure RkE(=O)l(OH)m (l =/= 0). Although the term is almost always applied to organic compounds, with carboxylic acid as the oxoacid, acyl groups can in principle be derived from other types of acids such as sulfonic acids or phosphonic acids." ; rdfs:subClassOf obo:CHEBI_33247 . obo:NCBITaxon_742000 a rdfs:Class ; rdfs:label "Bat SARS coronavirus HKU3-13" ; rdfs:subClassOf obo:NCBITaxon_442736 . obo:NCBITaxon_422217 a rdfs:Class ; rdfs:label "Bovine coronavirus E-AH65" ; rdfs:subClassOf obo:NCBITaxon_11128 . obo:NCBITaxon_694003 a rdfs:Class ; rdfs:label "Betacoronavirus 1" ; rdfs:subClassOf obo:NCBITaxon_2509481 . a rdfs:Class ; rdfs:label "Urticaria [Disease/Finding]" ; rdfs:subClassOf , . obo:CHEBI_33249 a rdfs:Class ; rdfs:label "organyl group" ; rdfs:comment "Any organic substituent group, regardless of functional type, having one free valence at a carbon atom." ; rdfs:subClassOf obo:CHEBI_51447 . obo:CHEBI_41550 a rdfs:Class ; rdfs:label "fluoroform" ; rdfs:subClassOf obo:CHEBI_39281 . obo:PR_P0DTC5 a rdfs:Class ; rdfs:label "membrane protein (SARS-CoV-2)" ; rdfs:comment "A protein that is a translation product of the M gene in SARS-CoV-2." ; rdfs:subClassOf obo:PR_000050262 . obo:CHEBI_45895 a rdfs:Class ; rdfs:label "tert-butanol" ; rdfs:comment "A tertiary alcohol alcohol that is isobutane substituted by a hydroxy group at position 2." ; rdfs:subClassOf obo:CHEBI_26878 . obo:CHEBI_35725 a rdfs:Class ; rdfs:label "isopropyl ester" ; rdfs:comment "Any carboxylic ester resulting from the formal condensation of a carboxylic acid with the hydroxy group of propan-2-ol." ; rdfs:subClassOf obo:CHEBI_33308 . a rdfs:Class ; rdfs:label "Phenazopyridine [Chemical/Ingredient]" ; rdfs:subClassOf . obo:NCBITaxon_2042548 a rdfs:Class ; rdfs:label "Coronavirus PREDICT CoV-21" ; rdfs:subClassOf obo:NCBITaxon_366617 . obo:PR_Q9H7F0 a rdfs:Class ; rdfs:label "polyamine-transporting ATPase 13A3 (human)" ; rdfs:comment "A polyamine-transporting ATPase 13A3 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000029067 , obo:PR_000029289 . obo:CIDO_0020073 a rdfs:Class ; rdfs:label "CentoSure SARS-CoV-2 RT-PCR Assay" ; rdfs:seeAlso ; rdfs:subClassOf obo:CIDO_0000454 . obo:PR_Q8MU52 a rdfs:Class ; rdfs:subClassOf obo:PR_000000001 . obo:PR_000050278 a rdfs:Class ; rdfs:label "non-structural protein 9 (SARS-CoV-2)" ; rdfs:comment "A rep gene proteolytic cleavage product (SARS-CoV-2) that is the central portion produced by the enzymatic action of 3CL-PRO proteinase (nsp5) when it cleaves the precursor rep gene translation product (SARS-CoV-2) between residues 4140-4141 and 4253-4254." ; rdfs:subClassOf obo:PR_000050281 . obo:NCBITaxon_931896 a rdfs:Class ; rdfs:label "Alphacoronavirus Eptesicus fuscus/Appalachian Ridge/P1-287740/IT/USA/2009" ; rdfs:subClassOf obo:NCBITaxon_366617 . obo:PR_Q9BRS2 a rdfs:Class ; rdfs:label "serine/threonine-protein kinase RIO1 (human)" ; rdfs:comment "A serine/threonine-protein kinase RIO1 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000014019 , obo:PR_000029067 . obo:PR_000003526 a rdfs:Class ; rdfs:label "AAK1 gene translation product" ; rdfs:comment "A protein that is a translation product of the human AAK1 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:CHEBI_35683 a rdfs:Class ; rdfs:label "aryl sulfide" ; rdfs:comment "Any organic sulfide in which the sulfur is attached to at least one aromatic group." ; rdfs:subClassOf obo:CHEBI_16385 . obo:VO_0005255 a rdfs:Class ; rdfs:label "ABNCoV2"@en ; rdfs:comment "A COVID-19 virus-like particle vaccine developed by Radboud University" ; rdfs:subClassOf obo:VO_0005205 . obo:PR_P04278 a rdfs:Class ; rdfs:label "sex hormone-binding globulin (human)" ; rdfs:comment "A sex hormone-binding globulin that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000014836 , obo:PR_000029067 . obo:NCBITaxon_903610 a rdfs:Class ; rdfs:label "Kenya bat coronavirus BtKY72" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:CHEBI_76710 a rdfs:Class ; rdfs:label "EC 4.* (lyase) inhibitor" ; rdfs:comment "An enzyme inhibitor which interferes with the action of a lyase (EC 4.*.*.*). Lyases are enzymes cleaving C-C, C-O, C-N and other bonds by other means than by hydrolysis or oxidation." ; rdfs:subClassOf obo:CHEBI_23924 . obo:PR_000014414 a rdfs:Class ; rdfs:label "protein S100-A7" ; rdfs:comment "A protein that is a translation product of the human S100A7 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:OBI_0000427 a rdfs:Class ; rdfs:label "enzyme"@en ; rdfs:comment """(protein or rna) or has_part (protein or rna) and has_function some GO:0003824 (catalytic activity)"""@en ; rdfs:subClassOf obo:BFO_0000040 . obo:HP_0012722 a rdfs:Class ; rdfs:label "Heart block" ; rdfs:comment "Impaired conduction of cardiac impulse occurring anywhere along the conduction pathway." ; rdfs:subClassOf obo:HP_0030956 . obo:GO_0015267 a rdfs:Class ; rdfs:label "channel activity" ; rdfs:comment "Enables the energy-independent facilitated diffusion, mediated by passage of a solute through a transmembrane aqueous pore or channel. Stereospecificity is not exhibited but this transport may be specific for a particular molecular species or class of molecules." ; rdfs:subClassOf obo:GO_0022857 . obo:CHEBI_38193 a rdfs:Class ; rdfs:label "phenylpyridine" ; rdfs:subClassOf obo:CHEBI_26421 . obo:CIDO_0000137 a rdfs:Class ; rdfs:label "MERS-CoV binding to host cell"@en ; rdfs:subClassOf obo:CIDO_0000134 . obo:NCBITaxon_256753 a rdfs:Class ; rdfs:label "SARS coronavirus GZ02" ; rdfs:subClassOf obo:NCBITaxon_694009 . a rdfs:Class ; rdfs:label "Decreased Serotonin Degradation [PE]" ; rdfs:subClassOf . obo:OBI_0600014 a rdfs:Class ; rdfs:label "material component separation"@en ; rdfs:comment "a material processing in which components of an input material become segregated in space"@en ; rdfs:subClassOf obo:OBI_0000094 . obo:CIDO_0020067 a rdfs:Class ; rdfs:label "CareStart COVID-19 Antigen test" ; rdfs:seeAlso ; rdfs:subClassOf obo:CIDO_0000454 . a rdfs:Class ; rdfs:label "Stomatognathic Diseases [Disease/Finding]" ; rdfs:subClassOf . obo:CHEBI_17824 a rdfs:Class ; rdfs:label "propan-2-ol" ; rdfs:comment "A secondary alcohol that is propane in which one of the hydrogens attached to the central carbon is substituted by a hydroxy group." ; rdfs:subClassOf obo:CHEBI_167095 , obo:CHEBI_35681 . obo:CHEBI_65323 a rdfs:Class ; rdfs:label "monoterpenoid indole alkaloid" ; rdfs:comment "A terpenoid indole alkaloid which is biosynthesised from L-tryptophan and diisoprenoid (usually secolaganin) building blocks." ; rdfs:subClassOf obo:CHEBI_65321 . obo:PR_000003622 a rdfs:Class ; rdfs:label "angiotensin-converting enzyme 2" ; rdfs:comment "A protein that is a translation product of the human ACE2 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:HP_0012443 a rdfs:Class ; rdfs:label "Abnormality of brain morphology" ; rdfs:comment "A structural abnormality of the brain, which has as its parts the forebrain, midbrain, and hindbrain." ; rdfs:subClassOf obo:HP_0002011 . obo:CIDO_0020172 a rdfs:Class ; rdfs:label "Illumina COVIDSeq Test" ; rdfs:seeAlso ; rdfs:subClassOf obo:CIDO_0000454 . obo:NCBITaxon_864602 a rdfs:Class ; rdfs:label "Bat coronavirus BM98-01/BGR/2008" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:CHEBI_25212 a rdfs:Class ; rdfs:label "metabolite" ; rdfs:comment "Any intermediate or product resulting from metabolism. The term 'metabolite' subsumes the classes commonly known as primary and secondary metabolites." ; rdfs:subClassOf obo:CHEBI_52206 . obo:GO_0006807 a rdfs:Class ; rdfs:label "nitrogen compound metabolic process" ; rdfs:comment "The chemical reactions and pathways involving organic or inorganic compounds that contain nitrogen." ; rdfs:subClassOf obo:GO_0008152 . obo:PR_Q13188 a rdfs:Class ; rdfs:label "serine/threonine-protein kinase 3 (human)" ; rdfs:comment "A serine/threonine-protein kinase 3 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000015746 , obo:PR_000029067 . a rdfs:Class ; rdfs:label "Smooth Muscle Tone Alteration [PE]" ; rdfs:subClassOf , . obo:NCBITaxon_502102 a rdfs:Class ; rdfs:label "Rat coronavirus Parker" ; rdfs:subClassOf obo:NCBITaxon_31632 . obo:CHEBI_32785 a rdfs:Class ; rdfs:label "tyrosinate(2-)" ; rdfs:subClassOf obo:CHEBI_33558 . obo:NCBITaxon_233044 a rdfs:Class ; rdfs:label "SARS coronavirus GD01" ; rdfs:subClassOf obo:NCBITaxon_694009 . obo:NCBITaxon_996628 a rdfs:Class ; rdfs:label "Bat coronavirus M.ful/Japan/01/2010" ; rdfs:subClassOf obo:NCBITaxon_366617 . obo:NCBITaxon_461309 a rdfs:Class ; rdfs:label "Rocky Mountain Bat Coronavirus 65" ; rdfs:subClassOf obo:NCBITaxon_366617 . obo:CHEBI_35213 a rdfs:Class ; rdfs:label "cyclodepsipeptide" ; rdfs:comment "A depsipeptide in which the amino and hydroxy carboxylic acid residues are connected in a ring." ; rdfs:subClassOf obo:CHEBI_23643 , obo:CHEBI_25000 . obo:VO_0005143 a rdfs:Class ; rdfs:label "LNP-nCoVsaRNA" ; rdfs:comment "A SARS-CoV-2 RNA vaccine made of self-coding RNA encoding SARS-CoV-2 spike protein encapsulated within a lipid nanoparticle." ; rdfs:subClassOf obo:VO_0005198 . obo:CHEBI_33253 a rdfs:Class ; rdfs:label "nucleon" ; rdfs:comment "Heavy nuclear particle: proton or neutron." ; rdfs:subClassOf obo:CHEBI_36339 , obo:CHEBI_36347 . obo:CHEBI_32508 a rdfs:Class ; rdfs:label "glycinate" ; rdfs:comment "An alpha-amino-acid anion that is the conjugate base of glycine, arising from deprotonation of the carboxy group." ; rdfs:subClassOf obo:CHEBI_33558 . obo:PR_P27448 a rdfs:Class ; rdfs:label "MAP/microtubule affinity-regulating kinase 3 (human)" ; rdfs:comment "A MAP/microtubule affinity-regulating kinase 3 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000010188 , obo:PR_000029067 . obo:OBI_0000651 a rdfs:Class ; rdfs:label "urine specimen" ; rdfs:comment "a portion of urine collected from an organism" ; rdfs:subClassOf obo:OBI_0001479 . obo:CIDO_0000275 a rdfs:Class ; rdfs:label "V70- in SARS-CoV-2 S protein" ; rdfs:subClassOf obo:CIDO_0001144 . obo:CIDO_0000964 a rdfs:Class ; rdfs:label "SARS-CoV2 orf10 protein binding to human ELOB" ; rdfs:comment "SARS-CoV2 orf10 protein binding to human ELOB, as evidented by an affinity-purification mass spectrometry experiment" ; rdfs:subClassOf obo:CIDO_0000050 . obo:PR_000000134 a rdfs:Class ; rdfs:label "tumor necrosis factor" ; rdfs:comment "A tumor necrosis factor, TNF-like that is a translation product of the human TNF gene or a 1:1 ortholog thereof. Tumour necrosis factor alpha (TNF) is a pleiotropic cytokine that mediates apoptosis, cell proliferation, immunomodulation, inflammation, viral replication, allergy, arthritis, septic shock, insulin resistance, autoimmune diseases, and other pathological conditions. TNF transduces these cellular responses through two distinct receptors: type I, which are expressed on all cell types, and type II, which are expressed only on cells of the immune system and endothelial cells." ; rdfs:subClassOf obo:PR_000000033 . obo:PR_000013420 a rdfs:Class ; rdfs:label "glutathione-requiring prostaglandin D synthase" ; rdfs:comment "A protein that is a translation product of the human HPGDS gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:CHEBI_51446 a rdfs:Class ; rdfs:label "organic divalent group" ; rdfs:subClassOf obo:CHEBI_33247 . obo:ENVO_00010505 a rdfs:Class ; rdfs:label "aerosol" ; rdfs:comment "Airborne solid particles (also called dust or particulate matter (PM)) or liquid droplets." ; rdfs:subClassOf obo:ENVO_00010483 . obo:CIDO_0001047 a rdfs:Class ; rdfs:label "SARS-CoV2 orf9c protein binding to human BCS1L" ; rdfs:comment "SARS-CoV2 orf9c protein binding to human BCS1L, as evidented by an affinity-purification mass spectrometry experiment" ; rdfs:subClassOf obo:CIDO_0000054 . obo:HP_0031860 a rdfs:Class ; rdfs:label "Abnormal heart rate variability" ; rdfs:comment "Any abnormality in the variability of the time interval between successive heartbeats." ; rdfs:subClassOf obo:HP_0011675 . obo:CHEBI_35640 a rdfs:Class ; rdfs:label "adrenergic uptake inhibitor" ; rdfs:comment "Adrenergic uptake inhibitors are drugs that block the transport of adrenergic transmitters into axon terminals or into storage vesicles within terminals. The tricyclic antidepressants and amphetamines are among the therapeutically important drugs that may act via inhibition of adrenergic transport. Many of these drugs also block transport of serotonin." ; rdfs:subClassOf obo:CHEBI_37962 . obo:CHEBI_28868 a rdfs:Class ; rdfs:label "fatty acid anion" ; rdfs:comment "The conjugate base of a fatty acid, arising from deprotonation of the carboxylic acid group of the corresponding fatty acid." ; rdfs:subClassOf obo:CHEBI_18059 , obo:CHEBI_35757 . a rdfs:Class ; rdfs:label "Decreased RNA Replication [PE]" ; rdfs:subClassOf . a rdfs:Class ; rdfs:label "Colonic Diseases [Disease/Finding]" ; rdfs:subClassOf . obo:GO_0051046 a rdfs:Class ; rdfs:label "regulation of secretion" ; rdfs:comment "Any process that modulates the frequency, rate or extent of the controlled release of a substance from a cell or a tissue." ; rdfs:subClassOf obo:GO_0051049 . obo:PR_O00124 a rdfs:Class ; rdfs:label "UBX domain-containing protein 8 (human)" ; rdfs:comment "A UBX domain-containing protein 8 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000017023 , obo:PR_000029067 . obo:CHEBI_76413 a rdfs:Class ; rdfs:label "greenhouse gas" ; rdfs:comment "A gas in an atmosphere that absorbs and emits radiation within the thermal infrared range, so contributing to the 'greenhouse effect'." ; rdfs:subClassOf obo:CHEBI_51086 . obo:CHEBI_6532 a rdfs:Class ; rdfs:label "loperamide" ; rdfs:comment "A synthetic piperidine derivative, effective against diarrhoea resulting from gastroenteritis or inflammatory bowel disease." ; rdfs:subClassOf obo:CHEBI_26151 , obo:CHEBI_26878 , obo:CHEBI_29347 , obo:CHEBI_83403 . obo:PR_000003060 a rdfs:Class ; rdfs:label "protein kinase C gamma type" ; rdfs:comment "A conventional protein kinase C that is a translation product of the human PRKCG gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000003057 . obo:OBI_0000237 a rdfs:Class ; rdfs:label "antigen role"@en ; rdfs:comment "a role that inheres in a vaccine component and plays an antigen role, i.e., it is introducd into an immune-competent organism to cause an immune response" ; rdfs:subClassOf obo:BFO_0000023 . obo:CHEBI_77941 a rdfs:Class ; rdfs:label "EC 3.5.1.4 (amidase) inhibitor" ; rdfs:comment "An EC 3.5.1.* (non-peptide linear amide C-N hydrolase) inhibitor that interferes with the action of amidase (EC 3.5.1.4)." ; rdfs:subClassOf obo:CHEBI_76807 . obo:PR_P06858 a rdfs:Class ; rdfs:label "lipoprotein lipase (human)" ; rdfs:comment "A lipoprotein lipase that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000009897 , obo:PR_000029067 . obo:NCBITaxon_2591228 a rdfs:Class ; rdfs:label "Coronavirus BtSk-AlphaCoV/GX2018A" ; rdfs:subClassOf obo:NCBITaxon_2691591 . obo:PR_P49643 a rdfs:Class ; rdfs:label "DNA primase large subunit (human)" ; rdfs:comment "A DNA primase large subunit that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000013216 , obo:PR_000029067 . a rdfs:Class ; rdfs:label "Thiethylperazine [Chemical/Ingredient]" ; rdfs:subClassOf , . a rdfs:Class ; rdfs:label "Myasthenia Gravis [Disease/Finding]" ; rdfs:subClassOf , . obo:CHEBI_77020 a rdfs:Class ; rdfs:label "EC 1.10.99.2 [ribosyldihydronicotinamide dehydrogenase (quinone)] inhibitor" ; rdfs:comment "An EC 1.10.99.* (oxidoreductases acting on diphenols and related substances as donors, other acceptors) inhibitor that interferes with the action of ribosyldihydronicotinamide dehydrogenase (quinone), EC 1.10.99.2." ; rdfs:subClassOf obo:CHEBI_77019 . obo:NCBITaxon_903585 a rdfs:Class ; rdfs:label "Kenya bat coronavirus BtKY47" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:PR_000009668 a rdfs:Class ; rdfs:label "La-related protein 1" ; rdfs:comment "A protein that is a translation product of the human LARP1 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:OBI_0001051 a rdfs:Class ; rdfs:label "DNA extract" ; rdfs:comment "The output of an extraction process in which DNA molecules are purified in order to exclude DNA from organellas." ; rdfs:subClassOf obo:OBI_0001010 . obo:PR_000010167 a rdfs:Class ; rdfs:label "MAP kinase-activated protein kinase 5" ; rdfs:comment "A protein that is a translation product of the human MAPKAPK5 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:APOLLO_SV_00000541 a rdfs:Class ; rdfs:label "disease surveillance objective specification"@en ; rdfs:comment "An objective specification whose endpoint is human awareness of the level of a particular disease in a particular population of a given biological taxon during some time interval."@en ; rdfs:subClassOf obo:IAO_0000005 . obo:UBERON_0004921 a rdfs:Class ; rdfs:label "subdivision of digestive tract" ; rdfs:comment "A proximal-distal subdivision of the digestive tract." ; rdfs:subClassOf obo:UBERON_0000064 . obo:PR_000015046 a rdfs:Class ; rdfs:label "very long-chain acyl-CoA synthetase" ; rdfs:comment "A protein that is a translation product of the human SLC27A2 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:OBI_0002608 a rdfs:Class ; rdfs:label "oropharyngeal swab specimen" ; rdfs:comment "A specimen that is collected with a swab from the surface of a oropharynx." ; rdfs:subClassOf obo:OBI_0002599 . obo:NCBITaxon_1679901 a rdfs:Class ; rdfs:label "Coronavirus RCoV/D_RMU10_592/Mic_arv/GER/2010" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:DOID_1596 a rdfs:Class ; rdfs:label "mental depression" ; rdfs:subClassOf obo:DOID_3324 . obo:CHEBI_50739 a rdfs:Class ; rdfs:label "estrogen receptor modulator" ; rdfs:comment "A substance that possess antiestrogenic actions but can also produce estrogenic effects as well. It acts as complete or partial agonist or as antagonist. It can be either steroidal or nonsteroidal in structure." ; rdfs:subClassOf obo:CHEBI_23888 . obo:NCBITaxon_1699330 a rdfs:Class ; rdfs:label "Myotis Bat Alphacoronavirus strain YNXY_20C" ; rdfs:subClassOf obo:NCBITaxon_366617 . obo:PR_Q9NRH2 a rdfs:Class ; rdfs:label "SNF-related serine/threonine-protein kinase (human)" ; rdfs:comment "An SNF-related serine/threonine-protein kinase that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000015331 , obo:PR_000029067 . obo:CIDO_0000730 a rdfs:Class ; rdfs:label "Q1011H in SARS-CoV-2 pp1b protein"@en ; rdfs:comment "An AA mutation or AA variant that has mutated an amino acid at position 1011 into a glutamine in pp1b." ; rdfs:subClassOf obo:CIDO_0001084 . obo:NCBITaxon_1503294 a rdfs:Class ; rdfs:label "BtMd-BetaCoV/HuB2013" ; rdfs:subClassOf obo:NCBITaxon_696098 . a rdfs:Class ; rdfs:label "Pancreatic Diseases [Disease/Finding]" ; rdfs:subClassOf . obo:PR_000003202 a rdfs:Class ; rdfs:label "calcium/calmodulin-dependent protein kinase type II subunit gamma" ; rdfs:comment "A calcium/calmodulin-dependent protein kinase type II chain that is a translation product of the human CAMK2G gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000003197 . obo:NCBITaxon_11145 a rdfs:Class ; rdfs:label "Murine hepatitis virus strain S" ; rdfs:subClassOf obo:NCBITaxon_11138 . a rdfs:Class ; rdfs:label "G [Preparations]" ; rdfs:subClassOf . obo:PR_000016169 a rdfs:Class ; rdfs:label "elongin-B" ; rdfs:comment "A protein that is a translation product of the human ELOB gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:PR_P35228 a rdfs:Class ; rdfs:label "nitric oxide synthase, inducible (human)" ; rdfs:comment "A nitric oxide synthase, inducible that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000001901 , obo:PR_000029067 . obo:CHEBI_147346 a rdfs:Class ; rdfs:label "SG85" ; rdfs:comment "A secondary carboxamide resulting from the formal condensation of the carboxy group of N-[(benzyloxy)carbonyl]-O-tert-butyl-L-serine with the primary amino group of ethyl (2E,4S)-5-[(3S)-2-oxopyrrolidin-3-yl]-4-(L-phenylalanylamino)pent-2-enoate. It is a potent enterovirus 3C protease inhibitor with EC50 of 180 nM against enterovirus 71 (EV71) and 60 nM against human rhinovirus 14 in a live virus-cell-based assay." ; rdfs:subClassOf obo:CHEBI_140325 , obo:CHEBI_23990 , obo:CHEBI_25698 , obo:CHEBI_51702 , obo:CHEBI_74223 , obo:CHEBI_84135 , obo:CHEBI_84144 , obo:CHEBI_90628 . a rdfs:Class ; rdfs:label "Cellular Motion Alteration [PE]" ; rdfs:subClassOf . obo:PR_Q8N4C8 a rdfs:Class ; rdfs:label "misshapen-like kinase 1 (human)" ; rdfs:comment "A misshapen-like kinase 1 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000010415 , obo:PR_000029067 . obo:PR_Q9UH99 a rdfs:Class ; rdfs:label "SUN domain-containing protein 2 (human)" ; rdfs:comment "A SUN domain-containing protein 2 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000017100 , obo:PR_000029067 . a rdfs:Class ; rdfs:label "Acneiform Eruptions [Disease/Finding]" ; rdfs:subClassOf . obo:PR_P58166 a rdfs:Class ; rdfs:label "inhibin beta E chain (human)" ; rdfs:comment "An activin/inhibin beta E chain that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000000219 , obo:PR_000029067 . obo:CHEBI_23690 a rdfs:Class ; rdfs:label "dicarboxylic acid amide" ; rdfs:subClassOf obo:CHEBI_37622 . obo:CHEBI_46767 a rdfs:Class ; rdfs:label "pyrrolidinecarboxylic acid" ; rdfs:subClassOf obo:CHEBI_38260 . obo:NCBITaxon_1288687 a rdfs:Class ; rdfs:label "Bat coronavirus POA/2012/105" ; rdfs:subClassOf obo:NCBITaxon_366617 . obo:CHEBI_46874 a rdfs:Class ; rdfs:label "alpha-amino acid ester" ; rdfs:comment "The amino acid ester derivative obtained the formal condensation of an alpha-amino acid with an alcohol." ; rdfs:subClassOf obo:CHEBI_46668 . obo:CIDO_0001207 a rdfs:Class ; rdfs:label "Multiple Real-Time PCR Kit for Detection of 2019-nCoV. (Maccura Biotechnology Co., Ltd.)" ; rdfs:comment "Poduct storage conditions and expiration date: This product is stored at -10℃~-30℃ and protected from light, and the validity period is 10 months." ; rdfs:subClassOf obo:CIDO_0000021 . obo:CHEBI_60911 a rdfs:Class ; rdfs:label "racemate" ; rdfs:comment "A racemate is an equimolar mixture of a pair of enantiomers." ; rdfs:subClassOf obo:CHEBI_60004 . a rdfs:Class ; rdfs:label "Pyrimidine Nucleosides [Chemical/Ingredient]" ; rdfs:subClassOf , . obo:DRON_00750784 a rdfs:Class ; rdfs:label "trametinib" ; rdfs:subClassOf obo:OBI_0000047 . a rdfs:Class ; rdfs:label "Decreased Serotonin Activity [PE]" ; rdfs:subClassOf , . a rdfs:Class ; rdfs:label "Tropanes [Chemical/Ingredient]" ; rdfs:subClassOf , . obo:CHEBI_35789 a rdfs:Class ; rdfs:label "oxo steroid" ; rdfs:subClassOf obo:CHEBI_17087 , obo:CHEBI_35341 . obo:CHEBI_17883 a rdfs:Class ; rdfs:label "hydrogen chloride" ; rdfs:comment "A mononuclear parent hydride consisting of covalently bonded hydrogen and chlorine atoms." ; rdfs:subClassOf obo:CHEBI_138675 , obo:CHEBI_18140 , obo:CHEBI_23117 , obo:CHEBI_37176 . obo:BFO_0000016 a rdfs:Class ; rdfs:label "disposition"@en ; rdfs:subClassOf obo:BFO_0000017 . obo:CHEBI_25985 a rdfs:Class ; rdfs:label "phenylalanine derivative" ; rdfs:comment "An amino acid derivative resulting from reaction of alanine at the amino group or the carboxy group, or from the replacement of any hydrogen of phenylalanine by a heteroatom. The definition normally excludes peptides containing phenylalanine residues." ; rdfs:subClassOf obo:CHEBI_83821 . a rdfs:Class ; rdfs:label "HYDROXYCHLOROQUINE SULFATE" ; rdfs:subClassOf . obo:NCBITaxon_389228 a rdfs:Class ; rdfs:label "Bat coronavirus (BtCoV/ A1074/2005)" ; rdfs:subClassOf obo:NCBITaxon_389126 . obo:HP_0011698 a rdfs:Class ; rdfs:label "Supraventricular tachycardia with a manifest accessory pathway on the septum" ; rdfs:subClassOf obo:HP_0011694 . obo:NCBITaxon_1679922 a rdfs:Class ; rdfs:label "Coronavirus RCoV/TP3_22/Ban_ind/THA/2005" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:CHEBI_24436 a rdfs:Class ; rdfs:label "guanidines" ; rdfs:comment "Any organonitrogen compound containing a carbamimidamido (guanidino) group. Guanidines have the general structure (R(1)R(2)N)(R(3)R(4)N)C=N-R(5) and are related structurally to amidines and ureas." ; rdfs:subClassOf obo:CHEBI_35352 . obo:NCBITaxon_903613 a rdfs:Class ; rdfs:label "Kenya bat coronavirus BtKY75" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:GO_0015711 a rdfs:Class ; rdfs:label "organic anion transport" ; rdfs:comment "The directed movement of organic anions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Organic anions are atoms or small molecules with a negative charge which contain carbon in covalent linkage." ; rdfs:subClassOf obo:GO_0006811 , obo:GO_0071702 . obo:PR_000007709 a rdfs:Class ; rdfs:label "mitochondrial import inner membrane translocase subunit Tim9 B" ; rdfs:comment "A protein that is a translation product of the human TIMM10B gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:CHEBI_49375 a rdfs:Class ; rdfs:label "dasatinib (anhydrous)" ; rdfs:comment "An aminopyrimidine that is 2-methylpyrimidine which is substituted at position 4 by the primary amino group of 2-amino-1,3-thiazole-5-carboxylic acid and at position 6 by a 4-(2-hydroxyethyl)piperazin-1-yl group, and in which the carboxylic acid group has been formally condensed with 2-chloro-6-methylaniline to afford the corresponding amide. A multi-targeted kinase inhibitor, it is used, particularly as the monohydrate, for the treatment of chronic, accelerated, or myeloid or lymphoid blast phase chronic myeloid leukemia. Note that the name 'dasatinib' is used to refer to the monohydrate (USAN) as well as to anhydrous dasatinib (INN)." ; rdfs:subClassOf obo:CHEBI_29347 , obo:CHEBI_36683 , obo:CHEBI_38338 , obo:CHEBI_38418 , obo:CHEBI_46848 , obo:CHEBI_46851 , obo:CHEBI_50995 , obo:CHEBI_50996 . obo:CIDO_0000125 a rdf:Property ; rdfs:label "chemical has protein target as potentiator"@en ; rdfs:comment "An object property that represents a relation between a chemical entity and a protein where the chemical entity can target the protein as a potentiator. Note that the chemical entity is usually an active compound of a corresponding drug. In clinical pharmacology, a potentiator is a drug, herb, or chemical that intensifies the effects of a given drug or protein regulator." ; rdfs:range ; rdfs:subPropertyOf obo:CIDO_0000118 . obo:PR_Q12851 a rdfs:Class ; rdfs:label "mitogen-activated protein kinase kinase kinase kinase 2 (human)" ; rdfs:comment "A mitogen-activated protein kinase kinase kinase kinase 2 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000010144 , obo:PR_000029067 . obo:NCBITaxon_2604656 a rdfs:Class ; rdfs:label "Betacoronavirus BtCoV22/29" ; rdfs:subClassOf obo:NCBITaxon_696098 . obo:CHEBI_32859 a rdfs:Class ; rdfs:label "valinate" ; rdfs:subClassOf obo:CHEBI_33558 , obo:CHEBI_63471 . obo:CIDO_0020168 a rdfs:Class ; rdfs:label "Hymon SARS-CoV-2 Test Kit" ; rdfs:seeAlso ; rdfs:subClassOf obo:CIDO_0000454 . obo:NCBITaxon_1346311 a rdfs:Class ; rdfs:label "Betacoronavirus BtCoV/Rhi_hip/R77-02/SPA/2010" ; rdfs:subClassOf obo:NCBITaxon_696098 . obo:CIDO_0000628 a rdfs:Class ; rdfs:label "D63G in SARS-CoV-2 N protein" ; rdfs:comment "An AA mutation or AA variant that has mutated an amino acid at position 63 into a glycine in N protein." ; rdfs:subClassOf obo:CIDO_0000596 . obo:OBI_0100067 a rdfs:Class ; rdfs:label "bronchial alveolar lavage"@en ; rdfs:comment "Group of biomaterials present in the bronchial aveolar space of an organism which are collected through lavage including the reagents used to for the lavage process, organisms, cells, and cellular secretions present in the bronchial aveolar space."@en ; rdfs:subClassOf obo:OBI_0100051 . obo:CIDO_0000311 a rdfs:Class ; rdfs:label "SLLIVNNATNVVIKV"@en ; rdfs:subClassOf obo:CIDO_0000314 . obo:CHEBI_5801 a rdfs:Class ; rdfs:label "hydroxychloroquine" ; rdfs:comment "An aminoquinoline that is chloroquine in which one of the N-ethyl groups is hydroxylated at position 2. An antimalarial with properties similar to chloroquine that acts against erythrocytic forms of malarial parasites, it is mainly used as the sulfate salt for the treatment of lupus erythematosus, rheumatoid arthritis, and light-sensitive skin eruptions." ; rdfs:subClassOf obo:CHEBI_15734 , obo:CHEBI_36683 , obo:CHEBI_36709 , obo:CHEBI_50995 , obo:CHEBI_50996 . obo:UBERON_0007650 a rdfs:Class ; rdfs:label "esophagogastric junction" ; rdfs:comment "The junction between the esophagus and the stomach epithelium" ; rdfs:subClassOf obo:UBERON_0000465 . obo:CHEBI_42485 a rdfs:Class ; rdfs:label "formyl group" ; rdfs:subClassOf obo:CHEBI_27207 . obo:CIDO_0020287 a rdfs:Class ; rdfs:label "SDI SARS-CoV-2 Assay" ; rdfs:seeAlso ; rdfs:subClassOf obo:CIDO_0000454 . obo:DRON_00000005 a rdfs:Class ; rdfs:label "drug product"@en ; rdfs:comment "a material entity (1) containing at least one scattered molecular aggregate as part that is the bearer of an active ingredient role and (2) that is itself the bearer of a clinical drug role"@en ; rdfs:subClassOf obo:BFO_0000040 . obo:OBI_0002515 a rdfs:Class ; rdfs:label "pleural fluid specimen" ; rdfs:comment "A specimen that is derived from pleural fluid." ; rdfs:subClassOf obo:OBI_2000009 . obo:NCBITaxon_2501926 a rdfs:Class ; rdfs:label "Rhinolophus ferrumequinum alphacoronavirus HuB-2013" ; rdfs:subClassOf obo:NCBITaxon_2509479 . obo:NCBITaxon_92931 a rdfs:Class ; rdfs:label "Rat sialodacryoadenitis coronavirus" ; rdfs:subClassOf obo:NCBITaxon_31632 . obo:CHEBI_147281 a rdfs:Class ; rdfs:label "GS-441524" ; rdfs:comment "A C-nucleoside analog that is (2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-carbonitrile substituted by a 4-aminopyrrolo[2,1-f][1,2,4]triazin-7-yl group at position 2. It is the active metabolite of remdesivir and exhibits a broad range of inhibitory activity against various RNA viruses including HCV, parainfluenza and SARS-CoV." ; rdfs:subClassOf obo:CHEBI_18379 , obo:CHEBI_33860 , obo:CHEBI_37086 , obo:CHEBI_88341 . obo:CHEBI_61951 a rdfs:Class ; rdfs:label "microtubule-destabilising agent" ; rdfs:comment "Any substance that interacts with tubulin to inhibit polymerisation of microtubules." ; rdfs:subClassOf obo:CHEBI_60832 , obo:CHEBI_64911 . obo:UBERON_0000165 a rdfs:Class ; rdfs:label "mouth" ; rdfs:comment "The proximal portion of the digestive tract, containing the oral cavity and bounded by the oral opening. In vertebrates, this extends to the pharynx and includes gums, lips, tongue and parts of the palate. Typically also includes the teeth, except where these occur elsewhere (e.g. pharyngeal jaws) or protrude from the mouth (tusks)." ; rdfs:seeAlso ; rdfs:subClassOf obo:UBERON_0000465 , obo:UBERON_0004921 . obo:NCBITaxon_260743 a rdfs:Class ; rdfs:label "SARS coronavirus NS-1" ; rdfs:subClassOf obo:NCBITaxon_694009 . obo:GO_0015844 a rdfs:Class ; rdfs:label "monoamine transport" ; rdfs:comment "The directed movement of monoamines, organic compounds that contain one amino group that is connected to an aromatic ring by an ethylene group (-CH2-CH2-), into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." ; rdfs:subClassOf obo:GO_0071702 , obo:GO_0071705 . obo:NCBITaxon_389230 a rdfs:Class ; rdfs:label "Bat coronavirus (BtCoV/133/2005)" ; rdfs:subClassOf obo:NCBITaxon_694007 . obo:NCBITaxon_658929 a rdfs:Class ; rdfs:label "Infectious bronchitis virus ITA/90254/2005" ; rdfs:subClassOf obo:NCBITaxon_11120 . obo:VO_0004711 a rdfs:Class ; rdfs:label "rMV- SARS-CoV -S/Ssol" ; rdfs:subClassOf obo:VO_0012183 . obo:CHEBI_145795 a rdfs:Class ; rdfs:label "digoxin(1-)" ; rdfs:comment "An organic anion that is the conjugate base of digoxin resulting from the deprotonation of furanone moiety; major species at pH 7.3." ; rdfs:subClassOf obo:CHEBI_25696 . obo:CHEBI_51285 a rdfs:Class ; rdfs:label "acenoquinone" ; rdfs:comment "Quinones containing an acene fused ring system." ; rdfs:subClassOf obo:CHEBI_36141 , obo:CHEBI_51269 . obo:DRON_00024808 a rdfs:Class ; rdfs:label "Azithromycin Injectable Solution" ; rdfs:subClassOf obo:DRON_00000020 . a rdfs:Class ; rdfs:label "Erythromycin [Chemical/Ingredient]" ; rdfs:subClassOf . obo:NCBITaxon_1429862 a rdfs:Class ; rdfs:label "Betacoronavirus Pipistrellus kuhlii/Italy/330375-15/2012" ; rdfs:subClassOf obo:NCBITaxon_696098 . obo:PR_P67870 a rdfs:Class ; rdfs:label "casein kinase II subunit beta (human)" ; rdfs:comment "A casein kinase II subunit beta that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000005952 , obo:PR_000029067 . obo:CIDO_0020089 a rdfs:Class ; rdfs:label "Cormeum SARS-CoV-2 Assay" ; rdfs:seeAlso ; rdfs:subClassOf obo:CIDO_0000454 . obo:IAO_0000030 a rdfs:Class ; rdfs:label "information content entity" ; rdfs:comment "an information content entity is an entity that is generically dependent on some artifact and stands in relation of aboutness to some entity"@en ; rdfs:subClassOf obo:BFO_0000002 , obo:BFO_0000031 . obo:NCBITaxon_2509487 a rdfs:Class ; rdfs:label "Igacovirus" ; rdfs:subClassOf obo:NCBITaxon_694013 . obo:CHEBI_51683 a rdfs:Class ; rdfs:label "methoxybenzenes" ; rdfs:comment "Any aromatic ether that consists of a benzene skeleton substituted with one or more methoxy groups." ; rdfs:subClassOf obo:CHEBI_22712 , obo:CHEBI_35618 . obo:OBCS_0000124 a rdfs:Class ; rdfs:label "inferential statistical data analysis objective"@en ; rdfs:comment "A statistical data analysis objective where the aim is to make inference using population sample data. " ; rdfs:subClassOf obo:OBI_0200166 . obo:CIDO_0000866 a rdfs:Class ; rdfs:label "SARS-CoV2 nsp15 protein binding to human ARF6" ; rdfs:comment "SARS-CoV2 nsp15 protein binding to human ARF6, as evidented by an affinity-purification mass spectrometry experiment" ; rdfs:subClassOf obo:CIDO_0000347 . obo:NCBITaxon_31631 a rdfs:Class ; rdfs:label "Human coronavirus OC43" ; rdfs:subClassOf obo:NCBITaxon_694003 . obo:CIDO_0000942 a rdfs:Class ; rdfs:label "SARS-CoV2 nsp8 protein binding to human NSD2" ; rdfs:comment "SARS-CoV2 nsp8 protein binding to human NSD2, as evidented by an affinity-purification mass spectrometry experiment" ; rdfs:subClassOf obo:CIDO_0000582 . obo:PR_000017149 a rdfs:Class ; rdfs:label "ubiquitin carboxyl-terminal hydrolase 13" ; rdfs:comment "A protein that is a translation product of the human USP13 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:CHEBI_76885 a rdfs:Class ; rdfs:label "EC 3.4.23.* (aspartic endopeptidase) inhibitor" ; rdfs:comment "An EC 3.4.* (hydrolases acting on peptide bond) inhibitor that interferes with the action of any aspartic endopeptidase (EC 3.4.23.*)." ; rdfs:subClassOf obo:CHEBI_60258 . obo:PR_000001423 a rdfs:Class ; rdfs:label "histamine H2 receptor" ; rdfs:comment "A histamine receptor that is a translation product of the human HRH2 gene or a 1:1 ortholog thereof. The preferred ligand is histamine. This receptor mediates smooth muscle relaxation, gastric acid secretion, and other diverse effects." ; rdfs:subClassOf obo:PR_000049994 . obo:CHEBI_32495 a rdfs:Class ; rdfs:label "D-phenylalaninium" ; rdfs:comment "An optically active form of phenylalaninium having D-configuration." ; rdfs:subClassOf obo:CHEBI_32505 . obo:NCBITaxon_903632 a rdfs:Class ; rdfs:label "Kenya bat coronavirus BtKY94" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:PR_000022007 a rdfs:Class ; rdfs:label "vertebrate-like neuraminidase" ; rdfs:comment "A protein that is a glycohydrolytic enzyme, which removes sialic acid residues from a variety of sialoglycoconjugates. Sialidases have highly conserved active site residues, the F/YRIV/P motif in the N-terminal part and the Asp boxes (consensus S/TXD(x)GxTW/F present as three to five repeat in the protein) similar to their viral and bacterial counter parts." ; rdfs:subClassOf obo:PR_000000001 . a rdfs:Class ; rdfs:label "Hypersensitivity [Disease/Finding]" ; rdfs:subClassOf . obo:PR_P07437 a rdfs:Class ; rdfs:label "tubulin beta chain (human)" ; rdfs:comment "A tubulin beta chain that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000029067 , obo:PR_000029780 . obo:DRON_00012193 a rdfs:Class ; rdfs:label "Proscillaridin" ; rdfs:subClassOf obo:OBI_0000047 . obo:GO_0006796 a rdfs:Class ; rdfs:label "phosphate-containing compound metabolic process" ; rdfs:comment "The chemical reactions and pathways involving the phosphate group, the anion or salt of any phosphoric acid." ; rdfs:subClassOf obo:GO_0006793 . obo:HP_0001300 a rdfs:Class ; rdfs:label "Parkinsonism" ; rdfs:comment "Characteristic neurologic anomaly resulting form degeneration of dopamine-generating cells in the substantia nigra, a region of the midbrain, characterized clinically by shaking, rigidity, slowness of movement and difficulty with walking and gait." ; rdfs:subClassOf obo:HP_0012638 . obo:OBI_0000341 a rdfs:Class ; rdfs:label "histological sample preparation"@en ; rdfs:comment "histological sample preparation is the preparation of an input tissue via slicing and labeling to make tissue microstructure of interest visible in a future histology assay"@en ; rdfs:subClassOf obo:OBI_0000094 , obo:OBI_0000659 . obo:CHEBI_74927 a rdfs:Class ; rdfs:label "furopyran" ; rdfs:comment "Any organic heterobicyclic compound containing ortho-fused furan and pyran rings." ; rdfs:subClassOf obo:CHEBI_27171 , obo:CHEBI_38104 . obo:PR_000000790 a rdfs:Class ; rdfs:label "voltage-gated potassium channel KCNH1" ; rdfs:comment "A voltage-gated potassium channel Eag alpha subunit that is a translation product of the human KCNH1 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000719 . obo:CHEBI_27369 a rdfs:Class ; rdfs:label "zwitterion" ; rdfs:comment "A neutral compound having formal unit electrical charges of opposite sign on non-adjacent atoms. Sometimes referred to as inner salts, dipolar ions (a misnomer)." ; rdfs:subClassOf obo:CHEBI_51151 . obo:CHEBI_23424 a rdfs:Class ; rdfs:label "cyanides" ; rdfs:comment "Salts and C-organyl derivatives of hydrogen cyanide, HC#N." ; rdfs:subClassOf obo:CHEBI_35352 . obo:PR_Q7Z7A1 a rdfs:Class ; rdfs:label "centriolin (human)" ; rdfs:comment "A centriolin that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000029067 , obo:PR_000029363 . a rdfs:Class ; rdfs:label "CHLOROQUINE" ; rdfs:subClassOf . obo:OBI_0002534 a rdfs:Class ; rdfs:label "lung specimen" ; rdfs:comment "A specimen that is derived from lung." ; rdfs:subClassOf obo:OBI_0001479 . obo:PR_000015624 a rdfs:Class ; rdfs:label "signal recognition particle 19 kDa protein" ; rdfs:comment "A protein that is a translation product of the human SRP19 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . a rdfs:Class ; rdfs:label "MYCOPHENOLATE" ; rdfs:subClassOf . obo:GO_0050482 a rdfs:Class ; rdfs:label "arachidonic acid secretion" ; rdfs:comment "The controlled release of arachidonic acid from a cell or a tissue." ; rdfs:subClassOf obo:GO_0032309 , obo:GO_1903963 . obo:PR_Q9Y5N1 a rdfs:Class ; rdfs:label "histamine H3 receptor (human)" ; rdfs:comment "A histamine H3 receptor that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000001564 , obo:PR_000029067 . obo:CIDO_0000051 a rdfs:Class ; rdfs:label "SARS-CoV-2 Orf8 protein interaction with host protein"@en ; rdfs:comment "A molecular interaction that has participant of the SARS-CoV-2 Orf10 protein and a host protein" ; rdfs:subClassOf obo:CIDO_0000348 . obo:NCBITaxon_2042589 a rdfs:Class ; rdfs:label "Coronavirus PREDICT CoV-65" ; rdfs:subClassOf obo:NCBITaxon_366617 . a rdfs:Class ; rdfs:label "Renal Excretion [PK]" ; rdfs:subClassOf . obo:NCBITaxon_2116470 a rdfs:Class ; rdfs:label "Guangdong chinese water skink coronavirus" ; rdfs:subClassOf obo:NCBITaxon_1986197 . obo:NCBITaxon_2559587 a rdfs:Class ; rdfs:label "Riboviria" ; rdfs:subClassOf obo:NCBITaxon_10239 . obo:OBI_0000370 a rdfs:Class ; rdfs:label "contain function"@en ; rdfs:comment "A contain function is a function to constrain a material entities location in space"@en ; rdfs:subClassOf obo:BFO_0000034 . obo:CIDO_0000698 a rdfs:Class ; rdfs:label "T19R in SARS-CoV-2 S protein" ; rdfs:comment "An AA mutation or AA variant that has mutated an amino acid at position 19 into a arginine in S protein." ; rdfs:subClassOf obo:CIDO_0000594 . obo:PR_000027795 a rdfs:Class ; rdfs:label "trypsin" ; rdfs:comment "A protein that in active form is a serine protease that cleaves peptide bonds on the carboxyl side of lysine or arginine amino acids within amino acid chains." ; rdfs:subClassOf obo:PR_000000001 . a rdfs:Class ; rdfs:label "Parkinson Disease [Disease/Finding]" ; rdfs:subClassOf , . obo:CHEBI_24898 a rdfs:Class ; rdfs:label "isoleucine" ; rdfs:comment "A 2-amino-3-methylpentanoic acid having either (2R,3R)- or (2S,3S)-configuration." ; rdfs:subClassOf obo:CHEBI_38264 . obo:NCBITaxon_2591235 a rdfs:Class ; rdfs:label "Coronavirus BtRs-BetaCoV/YN2018B" ; rdfs:subClassOf obo:NCBITaxon_2720068 . obo:PR_Q96B26 a rdfs:Class ; rdfs:label "exosome complex component RRP43 (human)" ; rdfs:comment "An exosome complex component RRP43 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000007265 , obo:PR_000029067 . obo:CHEBI_63470 a rdfs:Class ; rdfs:label "sulfur-containing amino-acid anion" ; rdfs:comment "A sulfur-containing amino acid whose alpha-carboxylic acid group is ionized (not protonated)." ; rdfs:subClassOf obo:CHEBI_37022 . obo:NCBITaxon_229206 a rdfs:Class ; rdfs:label "SARS coronavirus CUHK-Su10" ; rdfs:subClassOf obo:NCBITaxon_694009 . obo:GO_0050900 a rdfs:Class ; rdfs:label "leukocyte migration" ; rdfs:comment "The movement of a leukocyte within or between different tissues and organs of the body." ; rdfs:subClassOf obo:GO_0002376 , obo:GO_0016477 . obo:PR_O00203 a rdfs:Class ; rdfs:label "AP-3 complex subunit beta-1 (human)" ; rdfs:comment "An AP-3 complex subunit beta-1 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000004104 , obo:PR_000029067 . obo:UBERON_0001090 a rdfs:Class ; rdfs:label "synovial fluid" ; rdfs:comment "Joint fluid is a transudate of plasma that is actively secreted by synovial cells." ; rdfs:subClassOf obo:UBERON_0006314 . obo:PR_Q92918 a rdfs:Class ; rdfs:label "mitogen-activated protein kinase kinase kinase kinase 1 (human)" ; rdfs:comment "A mitogen-activated protein kinase kinase kinase kinase 1 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000010143 , obo:PR_000029067 . obo:CHEBI_48356 a rdfs:Class ; rdfs:label "protic solvent" ; rdfs:comment "A polar solvent that is capable of acting as a hydron (proton) donor." ; rdfs:subClassOf obo:CHEBI_39141 , obo:CHEBI_48354 . a rdfs:Class ; rdfs:label "Decreased Parasympathetic Acetylcholine Activity [PE]" ; rdfs:subClassOf , . obo:CHEBI_51614 a rdfs:Class ; rdfs:label "diarylmethane" ; rdfs:comment "Any compound containing two aryl groups connected by a single C atom." ; rdfs:subClassOf obo:CHEBI_33659 . obo:VO_0005273 a rdfs:Class ; rdfs:label "QazCoVac-P"@en ; rdfs:comment "A SARS-CoV-2 protein subunit vaccine manufactured by the Research Institute for Biological Safety Problems in Kazakhstan" ; rdfs:subClassOf obo:VO_0005202 . obo:CHEBI_28544 a rdfs:Class ; rdfs:label "digitoxin" ; rdfs:comment "A cardenolide glycoside in which the 3beta-hydroxy group of digitoxigenin carries a 2,6-dideoxy-beta-D-ribo-hexopyranosyl-(1->4)-2,6-dideoxy-beta-D-ribo-hexopyranosyl-(1->4)-2,6-dideoxy-beta-D-ribo-hexopyranosyl trisaccharide chain." ; rdfs:subClassOf obo:CHEBI_38092 . obo:NCBITaxon_1679921 a rdfs:Class ; rdfs:label "Coronavirus RCoV/SPB40/Liomys_spec/MEX/2011" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:CIDO_0020034 a rdfs:Class ; rdfs:label "Assure COVID-19 IgG/IgM Rapid Test Device" ; rdfs:seeAlso ; rdfs:subClassOf obo:CIDO_0000454 . obo:CHEBI_36347 a rdfs:Class ; rdfs:label "nuclear particle" ; rdfs:comment "A nucleus or any of its constituents in any of their energy states." ; rdfs:subClassOf obo:CHEBI_36342 . obo:VO_0005409 a rdfs:Class ; rdfs:label "mRNA-1073"@en ; rdfs:comment "A SARS-CoV-2 mRNA vaccine by Moderna that combines the mRNA-1273 COVID-19 vaccine and the mRNA-1010 influenza vaccine." ; rdfs:subClassOf obo:VO_0005198 . obo:CIDO_0000376 a rdfs:Class ; rdfs:label "SARS-CoV-2 Delta variant"@en ; rdfs:comment "Nextstrain clade 21A" ; rdfs:subClassOf obo:CIDO_0000407 . obo:CHEBI_61214 a rdfs:Class ; rdfs:label "promethazine(1+)" ; rdfs:comment "An ammonium ion that results from the protonation of the dimethyl-substituted nitrogen of promethazine." ; rdfs:subClassOf obo:CHEBI_35274 . obo:GO_0001775 a rdfs:Class ; rdfs:label "cell activation" ; rdfs:comment "A change in the morphology or behavior of a cell resulting from exposure to an activating factor such as a cellular or soluble ligand." ; rdfs:subClassOf obo:GO_0009987 . obo:CIDO_0000423 a rdfs:Class ; rdfs:label "coronavirus disease diagnostic process"@en ; rdfs:comment "A diagnostic process for detecting coronavirus disease from a patient" ; rdfs:subClassOf obo:OGMS_0000104 . a rdfs:Class ; rdfs:label "Hepatitis C [Disease/Finding]" ; rdfs:subClassOf , . obo:PR_P31994 a rdfs:Class ; rdfs:label "low affinity immunoglobulin gamma Fc region receptor II-b (human)" ; rdfs:comment "A low affinity immunoglobulin gamma Fc region receptor II-b that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000001481 , obo:PR_000029067 . obo:NCBITaxon_871679 a rdfs:Class ; rdfs:label "Feline coronavirus UU18" ; rdfs:subClassOf obo:NCBITaxon_12663 . obo:NCBITaxon_1679896 a rdfs:Class ; rdfs:label "Coronavirus RCoV/D_RMU10_2065/Myo_gla/GER/2010" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:CHEBI_48513 a rdfs:Class ; rdfs:label "carbazoles" ; rdfs:subClassOf obo:CHEBI_39205 . obo:CHEBI_46209 a rdfs:Class ; rdfs:label "L-tyrosinal" ; rdfs:comment "An amino aldehyde that is L-tyrosine in which the carboxy group has undergone formal redution to give the corrresponding aldehyde" ; rdfs:subClassOf obo:CHEBI_22492 , obo:CHEBI_33853 , obo:CHEBI_50994 . obo:OBI_0000419 a rdfs:Class ; rdfs:label "reverse transcriptase"@en ; rdfs:comment """enzyme and has_function some GO:0003964 (RNA-directed DNA polymerase activity)"""@en ; rdfs:subClassOf obo:OBI_0000427 . obo:NCBITaxon_903599 a rdfs:Class ; rdfs:label "Kenya bat coronavirus BtKY61" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:OBI_0002612 a rdfs:Class ; rdfs:label "fecal swab specimen" ; rdfs:comment "A specimen that is collected with a swab from the surface of a feces." ; rdfs:subClassOf obo:OBI_0002599 . obo:UBERON_0000064 a rdfs:Class ; rdfs:label "organ part" ; rdfs:comment "A multicellular structure that is a part of an organ." ; rdfs:subClassOf obo:UBERON_0010000 . obo:PR_000009198 a rdfs:Class ; rdfs:label "tyrosine-protein kinase JAK3" ; rdfs:comment "A Janus kinase that is a translation product of the human JAK3 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000025748 . a rdfs:Class ; rdfs:label "Acetylcholine Activity Alteration [PE]" ; rdfs:subClassOf . obo:NCBITaxon_1541205 a rdfs:Class ; rdfs:label "Bat Hp-betacoronavirus/Zhejiang2013" ; rdfs:subClassOf obo:NCBITaxon_2501961 . obo:GO_0044271 a rdfs:Class ; rdfs:label "cellular nitrogen compound biosynthetic process" ; rdfs:comment "The chemical reactions and pathways resulting in the formation of organic and inorganic nitrogenous compounds." ; rdfs:subClassOf obo:GO_0034641 , obo:GO_0044249 . a rdfs:Class ; rdfs:label "Monoamine Oxidase Inhibitors [MoA]" ; rdfs:subClassOf . obo:VO_0005232 a rdfs:Class ; rdfs:label "EuCorVac-19"@en ; rdfs:comment "A SARS-CoV-2 protein subunit vaccine by EuBiologics Co., Ltd." ; rdfs:subClassOf obo:VO_0005202 . obo:CHEBI_189682 a rdfs:Class ; rdfs:label "Translation Initiation Targets" ; rdfs:comment "The target that the mRNA translation initiates" ; rdfs:subClassOf obo:CHEBI_50860 . a rdfs:Class ; rdfs:label "Carboxylic Acids [Chemical/Ingredient]" ; rdfs:subClassOf . obo:NCBITaxon_745739 a rdfs:Class ; rdfs:label "Coronavirus M.das/VM284/2008/NLD" ; rdfs:subClassOf obo:NCBITaxon_696098 . obo:NCBITaxon_389256 a rdfs:Class ; rdfs:label "Bat coronavirus A701/2005" ; rdfs:subClassOf obo:NCBITaxon_366617 . obo:CIDO_0000657 a rdfs:Class ; rdfs:label "S49- in SARS-CoV-2 S protein" ; rdfs:comment "An AA mutation or AA variant that has mutated an amino acid at position 49 into a deletion" ; rdfs:subClassOf obo:CIDO_0001144 . obo:PR_000001777 a rdfs:Class ; rdfs:label "IKK-related kinase" ; rdfs:comment "A protein with a core domain composition consisting of one copy of the Protein kinase domain (Pfam:PF00069) at the N terminus, and with average length of about 720 residues. Members of this class have essential roles in innate immunity through signal-induced activation of IRF3 and IRF7." ; rdfs:subClassOf obo:PR_000000001 . obo:OBI_0000725 a rdfs:Class ; rdfs:label "host role" ; rdfs:comment "host role is a role played by an organism and realized by providing nourishment, shelter or a means of reproduction to another organism within the organism playing the host role" ; rdfs:subClassOf obo:BFO_0000023 . a rdfs:Class ; rdfs:label "Carbohydrate Metabolism Alteration [PE]" ; rdfs:subClassOf . obo:CHEBI_45783 a rdfs:Class ; rdfs:label "imatinib" ; rdfs:comment "A benzamide obtained by formal condensation of the carboxy group of 4-[(4-methylpiperazin-1-yl)methyl]benzoic acid with the primary aromatic amino group of 4-methyl-N(3)-[4-(pyridin-3-yl)pyrimidin-2-yl]benzene-1,3-diamine. Used (as its mesylate salt) for treatment of chronic myelogenous leukemia and gastrointestinal stromal tumours." ; rdfs:subClassOf obo:CHEBI_22702 , obo:CHEBI_26421 , obo:CHEBI_33860 , obo:CHEBI_39447 , obo:CHEBI_46920 . a rdfs:Class ; rdfs:label "F [Preparations]" ; rdfs:subClassOf . obo:PATO_0001995 a rdfs:Class ; rdfs:label "organismal quality" ; rdfs:comment "A quality that inheres in an entire organism or part of an organism." ; rdfs:subClassOf obo:PATO_0001237 , obo:PATO_0001241 . obo:CHEBI_77734 a rdfs:Class ; rdfs:label "dexverapamil" ; rdfs:comment "A 2-(3,4-dimethoxyphenyl)-5-{[2-(3,4-dimethoxyphenyl)ethyl](methyl)amino}-2-(propan-2-yl)pentanenitrile that has R configuration. It competitively inhibits the multidrug resistance efflux pump P-glycoprotein (MDR-1, EC 3.6.3.44), thereby potentially increasing the effectiveness of a wide range of antineoplastic drugs which are inactivated by MDR-1 mechanisms. Dexverapamil exhibits lower calcium antagonistic activity and toxicity than racemic verapamil." ; rdfs:subClassOf obo:CHEBI_77733 . obo:PR_000001439 a rdfs:Class ; rdfs:label "adenosine receptor protein" ; rdfs:comment "A rhodopsin-like G-protein coupled receptor that is a translation product of the human ADORA1, ADORA2A, ADORA2B, or ADORA3 genes, 1:1 orthologs thereof, or a semi-ortholog thereof. The active form binds adenosine." ; rdfs:subClassOf obo:PR_000001094 . obo:CIDO_0020310 a rdfs:Class ; rdfs:label "TRUPCR SARS-CoV-2 Kit" ; rdfs:seeAlso ; rdfs:subClassOf obo:CIDO_0000454 . obo:HP_0025015 a rdfs:Class ; rdfs:label "Abnormal vascular morphology"@en ; rdfs:subClassOf obo:HP_0002597 , obo:HP_0030680 . obo:OBI_0000740 a rdfs:Class ; rdfs:label "material sample role" ; rdfs:comment "A material sample role is a specimen role borne by a material entity that is the output of a material sampling process." ; rdfs:subClassOf obo:OBI_0000112 . obo:PR_000010130 a rdfs:Class ; rdfs:label "mitogen-activated protein kinase kinase kinase 11" ; rdfs:comment "A protein that is a translation product of the human MAP3K11 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . a rdfs:Class ; rdfs:label "Thrombocytopenia [Disease/Finding]" ; rdfs:subClassOf . obo:PR_Q9Y5J7 a rdfs:Class ; rdfs:label "mitochondrial import inner membrane translocase subunit Tim9 (human)" ; rdfs:comment "A mitochondrial import inner membrane translocase subunit Tim9 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000016351 , obo:PR_000029067 . obo:PR_000012960 a rdfs:Class ; rdfs:label "DNA polymerase alpha catalytic subunit" ; rdfs:comment "A protein that is a translation product of the human POLA1 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:NCBITaxon_1788462 a rdfs:Class ; rdfs:label "Miniopterus bat coronavirus BtCoV/3728-2" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:OBI_0001912 a rdfs:Class ; rdfs:label "cell freezing medium"@en ; rdfs:comment "A processed material that serves as a liquid vehicle for freezing cells for long term quiescent stroage, which contains chemicls needed to sustain cell viability across freeze-thaw cycles. " ; rdfs:subClassOf obo:OBI_0000047 . obo:PR_000005051 a rdfs:Class ; rdfs:label "peripheral plasma membrane protein CASK" ; rdfs:comment "A protein that is a translation product of the human CASK gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:GO_0040012 a rdfs:Class ; rdfs:label "regulation of locomotion" ; rdfs:comment "Any process that modulates the frequency, rate or extent of locomotion of a cell or organism." ; rdfs:subClassOf obo:GO_0050789 . obo:GO_0080090 a rdfs:Class ; rdfs:label "regulation of primary metabolic process" ; rdfs:comment "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways within a cell or an organism involving those compounds formed as a part of the normal anabolic and catabolic processes. These processes take place in most, if not all, cells of the organism." ; rdfs:subClassOf obo:GO_0019222 . a rdfs:Class ; rdfs:label "Nucleic Acids, Nucleotides, and Nucleosides [Chemical/Ingredient]" ; rdfs:subClassOf . obo:CIDO_0000527 a rdfs:Class ; rdfs:label "NIEAWLNDKSVPSPL" ; rdfs:comment "A coronavirus epitope that is part of some S protein from HCoV OC43 composed of the following amino acids NIEAWLNDKSVPSPL" ; rdfs:subClassOf obo:CIDO_0000452 . obo:GO_0007165 a rdfs:Class ; rdfs:label "signal transduction" ; rdfs:comment "The cellular process in which a signal is conveyed to trigger a change in the activity or state of a cell. Signal transduction begins with reception of a signal (e.g. a ligand binding to a receptor or receptor activation by a stimulus such as light), or for signal transduction in the absence of ligand, signal-withdrawal or the activity of a constitutively active receptor. Signal transduction ends with regulation of a downstream cellular process, e.g. regulation of transcription or regulation of a metabolic process. Signal transduction covers signaling from receptors located on the surface of the cell and signaling via molecules located within the cell. For signaling between cells, signal transduction is restricted to events at and within the receiving cell." ; rdfs:subClassOf obo:GO_0009987 , obo:GO_0050794 . obo:CHEBI_53292 a rdfs:Class ; rdfs:label "(R)-donepezil" ; rdfs:comment "A 2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimethoxyindan-1-one that has R configuration." ; rdfs:subClassOf obo:CHEBI_145499 . obo:CHEBI_45557 a rdfs:Class ; rdfs:label "sec-butyl group" ; rdfs:subClassOf obo:CHEBI_22323 , obo:CHEBI_50325 . obo:CIDO_0000371 a rdfs:Class ; rdfs:label "SARS-CoV-2 Alpha variant"@en ; rdfs:subClassOf obo:CIDO_0000407 . a rdfs:Class ; rdfs:label "Pyrans [Chemical/Ingredient]" ; rdfs:subClassOf . obo:VO_0005082 a rdfs:Class ; rdfs:label "Abdala"@en ; rdfs:comment "A SARS-CoV-2 protein subunit vaccine based on recombinant RBD subunits manufactured by the Center for Genetic Engineering and Biotechnology (CIGB)." ; rdfs:subClassOf obo:VO_0005202 , obo:VO_0005269 . obo:CHEBI_35444 a rdfs:Class ; rdfs:label "antinematodal drug" ; rdfs:comment "A substance used in the treatment or control of nematode infestations." ; rdfs:subClassOf obo:CHEBI_25491 , obo:CHEBI_35443 . obo:HP_0031628 a rdfs:Class ; rdfs:label "Aborted sudden cardiac death" ; rdfs:comment "Cardiac arrest that would have led to rapid and unexpected death had an intervention not taken place to prevent it." ; rdfs:subClassOf obo:HP_0001695 . obo:NCBITaxon_1699358 a rdfs:Class ; rdfs:label "Hipposideros Bat Alphacoronavirus strain MJ_55C" ; rdfs:subClassOf obo:NCBITaxon_366617 . obo:PR_Q13177 a rdfs:Class ; rdfs:label "serine/threonine-protein kinase PAK 2 (human)" ; rdfs:comment "A serine/threonine-protein kinase PAK 2 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000012241 , obo:PR_000029067 . obo:PR_Q9H2G2 a rdfs:Class ; rdfs:label "STE20-like serine/threonine-protein kinase (human)" ; rdfs:comment "A STE20-like serine/threonine-protein kinase that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000015243 , obo:PR_000029067 . obo:NCBITaxon_2042537 a rdfs:Class ; rdfs:label "Coronavirus PREDICT CoV-10" ; rdfs:subClassOf obo:NCBITaxon_696098 . obo:CHEBI_5686 a rdfs:Class ; rdfs:label "heterocyclic compound" ; rdfs:comment "A cyclic compound having as ring members atoms of at least two different elements." ; rdfs:subClassOf obo:CHEBI_33595 . obo:PR_000015250 a rdfs:Class ; rdfs:label "pre-mRNA-splicing factor SLU7" ; rdfs:comment "A protein that is a translation product of the human SLU7 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:NCBITaxon_1788477 a rdfs:Class ; rdfs:label "Miniopterus bat coronavirus BtCoV/4039" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:CHEBI_26961 a rdfs:Class ; rdfs:label "thiophenes" ; rdfs:comment "Compounds containing at least one thiophene ring." ; rdfs:subClassOf obo:CHEBI_38106 . obo:CIDO_0001058 a rdfs:Class ; rdfs:label "SARS-CoV2 orf9c protein binding to human NLRX1" ; rdfs:comment "SARS-CoV2 orf9c protein binding to human NLRX1, as evidented by an affinity-purification mass spectrometry experiment" ; rdfs:subClassOf obo:CIDO_0000054 . obo:NCBITaxon_749425 a rdfs:Class ; rdfs:label "Brent goose coronavirus KR-88" ; rdfs:subClassOf obo:NCBITaxon_749416 . a rdfs:Class ; rdfs:label "Ascaridida Infections [Disease/Finding]" ; rdfs:subClassOf . obo:CHEBI_64932 a rdfs:Class ; rdfs:label "cathepsin B inhibitor" ; rdfs:comment "A cysteine protease inhibitor which inhibits cathepsin B (EC 3.4.22.1)." ; rdfs:subClassOf obo:CHEBI_64152 . obo:GO_0009628 a rdfs:Class ; rdfs:label "response to abiotic stimulus" ; rdfs:comment "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an abiotic (not derived from living organisms) stimulus." ; rdfs:subClassOf obo:GO_0050896 . obo:CHEBI_140601 a rdfs:Class ; rdfs:label "fatty acid 4:0" ; rdfs:comment "Any saturated fatty acid containing 4 carbons." ; rdfs:subClassOf obo:CHEBI_26666 . obo:VO_0005345 a rdfs:Class ; rdfs:label "PIKA Recombinant COVID-19 Vaccine"@en ; rdfs:comment "A SARS-CoV-2 subunit vaccine by Yisheng Biopharma" ; rdfs:subClassOf obo:VO_0005202 . obo:GO_0008284 a rdfs:Class ; rdfs:label "positive regulation of cell population proliferation" ; rdfs:comment "Any process that activates or increases the rate or extent of cell proliferation." ; rdfs:subClassOf obo:GO_0042127 , obo:GO_0048522 . obo:PR_000036197 a rdfs:Class ; rdfs:label "viral protein" ; rdfs:comment "A protein that is encoded in the genome of some virus." ; rdfs:subClassOf obo:PR_000000001 . a rdfs:Class ; rdfs:label "Steroids [Chemical/Ingredient]" ; rdfs:subClassOf . obo:NCBITaxon_1225486 a rdfs:Class ; rdfs:label "Bat coronavirus CAR/P 25/2009" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:OPMI_0000498 a rdfs:Class ; rdfs:label "laboratory visit"@en ; rdfs:comment "A visit to a dedicated institution, at a care site, within one day, for the purpose of a measurement. The visit is carried out in a medical laboratory or clinical laboratory where tests are carried out on clinical specimens to obtain information about the health of a patient to aid in diagnosis, treatment, and prevention of disease" ; rdfs:subClassOf obo:OPMI_0000482 . obo:CHEBI_175901 a rdfs:Class ; rdfs:label "gemcitabine" ; rdfs:comment "A 2'-deoxycytidine having geminal fluoro substituents in the 2'-position. Gemcitabine is used in various carcinomas: non-small cell lung cancer, pancreatic cancer, bladder cancer and breast cancer." ; rdfs:subClassOf obo:CHEBI_19255 , obo:CHEBI_37143 . obo:CIDO_0001009 a rdfs:Class ; rdfs:label "Vazegepant" ; rdfs:subClassOf obo:CHEBI_23367 . obo:VO_0000617 a rdfs:Class ; rdfs:label "vaccine component role"@en ; rdfs:subClassOf obo:BFO_0000023 . obo:NCBITaxon_497938 a rdfs:Class ; rdfs:label "Bat coronavirus M.das/Germany/D3.33/2007" ; rdfs:subClassOf obo:NCBITaxon_366617 . obo:PR_Q06187 a rdfs:Class ; rdfs:label "tyrosine-protein kinase BTK (human)" ; rdfs:comment "A tyrosine-protein kinase BTK that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000002110 , obo:PR_000029067 . obo:NCBITaxon_424361 a rdfs:Class ; rdfs:label "Bat coronavirus HKU4-3" ; rdfs:subClassOf obo:NCBITaxon_694007 . obo:CIDO_0000286 a rdfs:Class ; rdfs:label "SARS-CoV-2 life cycle stage"@en ; rdfs:subClassOf obo:CIDO_0000285 . obo:CIDO_0000875 a rdfs:Class ; rdfs:label "SARS-CoV2 nsp2 protein binding to human WASHC4" ; rdfs:comment "SARS-CoV2 nsp2 protein binding to human WASHC4, as evidented by an affinity-purification mass spectrometry experiment" ; rdfs:subClassOf obo:CIDO_0000580 . obo:VO_0005262 a rdfs:Class ; rdfs:label "MVA-SARS-2-ST"@en ; rdfs:comment "A SARS-CoV-2 recombinant viral vector vaccine by the German Center for Infection Research" ; rdfs:subClassOf obo:VO_0005199 . obo:NCBITaxon_622718 a rdfs:Class ; rdfs:label "Bat coronavirus Hipposideros/GhanaKwam/8/2008" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:CHEBI_2208 a rdfs:Class ; rdfs:label "purine-6-thiol" ; rdfs:comment "A thiol that is the tautomer of mercaptopurine." ; rdfs:subClassOf obo:CHEBI_82711 . obo:NCBITaxon_864592 a rdfs:Class ; rdfs:label "Bat coronavirus BB98-41/BGR/2008" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:CIDO_0001140 a rdfs:Class ; rdfs:label "SARS-CoV-2 BA.4 virus"@en ; rdfs:comment "A SARS-CoV-2 Omicron variant virus that is identified with the following characteristics." ; rdfs:subClassOf obo:CIDO_0000406 , obo:CIDO_0000590 . obo:CHEBI_15740 a rdfs:Class ; rdfs:label "formate" ; rdfs:comment "A monocarboxylic acid anion that is the conjugate base of formic acid. Induces severe metabolic acidosis and ocular injury in human subjects." ; rdfs:subClassOf obo:CHEBI_35757 . obo:PR_000001355 a rdfs:Class ; rdfs:label "immunoglobulin gamma Fc receptor II/III/IV" ; rdfs:comment "A protein with a core domain architecture consisting of an extracellular domain containing two copies of the Immunoglobulin domain (Pfam:PF00047), followed by a single-pass transmembrane region and a small intracellular domain. The active protein is a low affinity receptor for immunoglobulin gamma chain Fc region. Human II-a, II-b, and II-c represent a recent gene expansion and are equally related to mouse II, III, and IV. Human III-A and III-B are closely related and closer to mouse IV than to mouse III." ; rdfs:subClassOf obo:PR_000000001 . a rdfs:Class ; rdfs:label "Increased Immunologic Activity [PE]" ; rdfs:subClassOf . obo:PR_000035365 a rdfs:Class ; rdfs:label "aurora kinase" ; rdfs:comment "A protein that is a serine-threonine protein kinase that controls several aspects of cell division. It contains a copy of the Protein kinase domain (Pfam:PF00069)." ; rdfs:subClassOf obo:PR_000000001 . obo:NCBITaxon_249062 a rdfs:Class ; rdfs:label "SARS coronavirus GZ-A" ; rdfs:subClassOf obo:NCBITaxon_694009 . obo:PR_Q9Y3U8 a rdfs:Class ; rdfs:label "60S ribosomal protein L36 (human)" ; rdfs:comment "A 60S ribosomal protein L36 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000014219 , obo:PR_000029067 . obo:CHEBI_30356 a rdfs:Class ; rdfs:label "isobutyl group" ; rdfs:subClassOf obo:CHEBI_22323 , obo:CHEBI_50325 . obo:CIDO_0000206 a rdfs:Class ; rdfs:label "SARS-CoV-2 pp1ab cleavage"@en ; rdfs:subClassOf obo:CIDO_0000179 , obo:CIDO_0000197 . obo:DRON_00015096 a rdfs:Class ; rdfs:label "ifenprodil" ; rdfs:subClassOf obo:OBI_0000047 . obo:PR_P40189 a rdfs:Class ; rdfs:label "interleukin-6 receptor subunit beta (human)" ; rdfs:comment "An interleukin-6 receptor subunit beta that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000001868 , obo:PR_000029067 . obo:NCBITaxon_5761 a rdfs:Class ; rdfs:label "Naegleria" ; rdfs:subClassOf obo:NCBITaxon_2611352 . obo:CHEBI_38323 a rdfs:Class ; rdfs:label "cholinergic drug" ; rdfs:comment "Any drug used for its actions on cholinergic systems. Included here are agonists and antagonists, drugs that affect the life cycle of acetylcholine, and drugs that affect the survival of cholinergic neurons." ; rdfs:subClassOf obo:CHEBI_35942 . obo:VO_0005091 a rdfs:Class ; rdfs:label "LV-SMENP-DC"@en ; rdfs:comment "A SARS-CoV-2 recombinant vector vaccine by Shenzhen Geno-Immune Medical Institute" ; rdfs:subClassOf obo:VO_0005199 . obo:CIDO_0020116 a rdfs:Class ; rdfs:label "Diazyme DZ-Lite SARS-CoV-2 IgM CLIA Kit" ; rdfs:seeAlso ; rdfs:subClassOf obo:CIDO_0000454 . obo:NCBITaxon_1433214 a rdfs:Class ; rdfs:label "unclassified Gammacoronavirus" ; rdfs:subClassOf obo:NCBITaxon_694013 . obo:APOLLO_SV_00000552 a rdfs:Class ; rdfs:label "metapopulation disease transmission model"@en ; rdfs:comment "A disease transmission model that is about two or more collections of organisms of a particular biological taxon in separate geographical locations and some geographical migration of organisms between them."@en ; rdfs:subClassOf obo:APOLLO_SV_00000174 . obo:NCBITaxon_7742 a rdfs:Class ; rdfs:label "Vertebrata " ; rdfs:subClassOf obo:NCBITaxon_33213 , obo:NCBITaxon_89593 . obo:CHEBI_24062 a rdfs:Class ; rdfs:label "fluorine molecular entity" ; rdfs:subClassOf obo:CHEBI_24471 . obo:CIDO_0000203 a rdfs:Class ; rdfs:label "coronaviral RTC proofreading"@en ; rdfs:subClassOf obo:CIDO_0000204 . obo:CHEBI_6601 a rdfs:Class ; rdfs:label "lycorine" ; rdfs:comment "An indolizidine alkaloid that is 3,12-didehydrogalanthan substituted by hydroxy groups at positions and 2 and a methylenedioxy group across positions 9 and 10. Isolated from Crinum asiaticum, it has been shown to exhibit antimalarial activity." ; rdfs:subClassOf obo:CHEBI_38511 . obo:NCBITaxon_1346304 a rdfs:Class ; rdfs:label "Betacoronavirus BtCoV/Rhi_fer/It15/ITA/2009" ; rdfs:subClassOf obo:NCBITaxon_696098 . obo:NCBITaxon_2078583 a rdfs:Class ; rdfs:label "Pigeon coronavirus UAE-HKU29" ; rdfs:subClassOf obo:NCBITaxon_2724161 . obo:NCBITaxon_627439 a rdfs:Class ; rdfs:label "Human enteric coronavirus strain 4408" ; rdfs:subClassOf obo:NCBITaxon_166124 . obo:VO_0005132 a rdfs:Class ; rdfs:label "rVV-SARS vaccine" ; rdfs:comment "A MERS DNA vaccine made of plasmid vaccines that encoded S1 subunit only" ; rdfs:subClassOf obo:VO_0012183 . obo:NCBITaxon_207598 a rdfs:Class ; rdfs:label "Homininae" ; rdfs:subClassOf obo:NCBITaxon_9604 . obo:NCBITaxon_1503283 a rdfs:Class ; rdfs:label "BtMf-AlphaCoV/HeN2013" ; rdfs:subClassOf obo:NCBITaxon_694001 . obo:GO_0051338 a rdfs:Class ; rdfs:label "regulation of transferase activity" ; rdfs:comment "Any process that modulates the frequency, rate or extent of transferase activity, the catalysis of the transfer of a group, e.g. a methyl group, glycosyl group, acyl group, phosphorus-containing, or other groups, from one compound (generally regarded as the donor) to another compound (generally regarded as the acceptor). Transferase is the systematic name for any enzyme of EC class 2." ; rdfs:subClassOf obo:GO_0050790 . obo:PR_000014212 a rdfs:Class ; rdfs:label "60S ribosomal protein L3" ; rdfs:comment "A protein that is a translation product of the human RPL3 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:NCBITaxon_11142 a rdfs:Class ; rdfs:label "Murine hepatitis virus strain A59" ; rdfs:subClassOf obo:NCBITaxon_11138 . obo:IDO_0000502 a rdfs:Class ; rdfs:label "infectious disease epidemic"@en ; rdfs:comment "A process of infectious disease realizations and for which there is a statistically significant increase in the infectious disease incidence of a population."@en ; rdfs:subClassOf obo:BFO_0000015 . obo:PR_P0DTD3 a rdfs:Class ; rdfs:label "putative ORF9c protein (SARS-CoV-2)" ; rdfs:comment "A protein that is a translation product of the ORF9c gene in SARS-CoV-2." ; rdfs:subClassOf obo:PR_000050262 . obo:CIDO_0020335 a rdfs:Class ; rdfs:label "Wren Laboratories COVID-19 PCR Test" ; rdfs:seeAlso ; rdfs:subClassOf obo:CIDO_0000454 . obo:GO_0051707 a rdfs:Class ; rdfs:label "response to other organism" ; rdfs:comment "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from another living organism." ; rdfs:subClassOf obo:GO_0043207 , obo:GO_0044419 . a rdfs:Class ; rdfs:label "Slow Virus Diseases [Disease/Finding]" ; rdfs:subClassOf obo:DOID_934 . obo:PR_000029101 a rdfs:Class ; rdfs:label "dephospho-CoA kinase domain-containing protein" ; rdfs:comment "A protein that is a translation product of the human DCAKD gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:ENVO_00010483 a rdfs:Class ; rdfs:label "environmental material" ; rdfs:comment "A portion of environmental material is a fiat object part which forms the medium or part of the medium of an environmental system." ; rdfs:subClassOf obo:BFO_0000040 . obo:PR_P55085 a rdfs:Class ; rdfs:label "proteinase-activated receptor 2 (human)" ; rdfs:comment "A proteinase-activated receptor 2 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000001662 , obo:PR_000029067 . obo:CIDO_0000151 a rdfs:Class ; rdfs:label "coronaviral disease pandemic"@en ; rdfs:subClassOf obo:IDO_0000503 . obo:PR_000004396 a rdfs:Class ; rdfs:label "arginyl-tRNA--protein transferase 1" ; rdfs:comment "A protein that is a translation product of the human ATE1 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:CHEBI_170010 a rdfs:Class ; rdfs:label "EC 2.7.7.48 (RNA-directed RNA polymerase) inhibitor" ; rdfs:comment "A DNA polymerase inhibitor that interferes with the action of a RNA-directed RNA polymerase (EC 2.7.7.48)." ; rdfs:subClassOf obo:CHEBI_38234 . obo:PR_Q99759 a rdfs:Class ; rdfs:label "mitogen-activated protein kinase kinase kinase 3 (human)" ; rdfs:comment "A mitogen-activated protein kinase kinase kinase 3 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000010136 , obo:PR_000029067 . obo:PR_P35555 a rdfs:Class ; rdfs:label "fibrillin-1 (human)" ; rdfs:comment "A fibrillin-1 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000007362 , obo:PR_000029067 . obo:PR_000007744 a rdfs:Class ; rdfs:label "Ras GTPase-activating protein-binding protein 2" ; rdfs:comment "A protein that is a translation product of the human G3BP2 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:CHEBI_23117 a rdfs:Class ; rdfs:label "chlorine molecular entity" ; rdfs:comment "A halogen molecular entity containing one or more atoms of chlorine." ; rdfs:subClassOf obo:CHEBI_24471 . obo:CHEBI_60654 a rdfs:Class ; rdfs:label "valproate" ; rdfs:comment "A branched-chain saturated fatty acid anion that is the conjugate base of valproic acid." ; rdfs:subClassOf obo:CHEBI_58956 . obo:VO_0000447 a rdfs:Class ; rdfs:label "poxvirus vaccine vector" ; rdfs:comment "a viral vaccine vector that uses an poxvirus as the vector." ; rdfs:subClassOf obo:VO_0000610 . obo:NCBITaxon_384346 a rdfs:Class ; rdfs:label "Human coronavirus NO/0193/05" ; rdfs:subClassOf obo:NCBITaxon_384335 . obo:PR_000007130 a rdfs:Class ; rdfs:label "ephrin type-B receptor 2" ; rdfs:comment "An ephrin receptor that is a translation product of the human EPHB2 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000025845 . obo:CHEBI_32774 a rdfs:Class ; rdfs:label "D-tyrosinate(2-)" ; rdfs:comment "The D-enantiomer of tyrosinate(2-)." ; rdfs:subClassOf obo:CHEBI_32785 . a rdfs:Class ; rdfs:label "Chlorobenzenes [Chemical/Ingredient]" ; rdfs:subClassOf , . obo:CHEBI_32695 a rdfs:Class ; rdfs:label "argininate" ; rdfs:subClassOf obo:CHEBI_33558 . obo:CHEBI_91007 a rdfs:Class ; rdfs:label "aromatic carboxylate" ; rdfs:comment "A carboxylic acic anion obtained by deprotonation of the carboxy group of any aromatic carboxylic acid. Major species at pH 7.3." ; rdfs:subClassOf obo:CHEBI_29067 . obo:CHEBI_61692 a rdfs:Class ; rdfs:label "pyridoisoquinoline" ; rdfs:comment "An organic heterotricyclic compound with a skeleton derived from a pyridine ring fused to an isoquinoline." ; rdfs:subClassOf obo:CHEBI_26979 . obo:NCBITaxon_1415838 a rdfs:Class ; rdfs:label "Bat SARS-like coronavirus Rs4080" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:CHEBI_33242 a rdfs:Class ; rdfs:label "inorganic hydride" ; rdfs:subClassOf obo:CHEBI_24835 , obo:CHEBI_33692 . obo:GO_0046890 a rdfs:Class ; rdfs:label "regulation of lipid biosynthetic process" ; rdfs:comment "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of lipids." ; rdfs:subClassOf obo:GO_0009889 , obo:GO_0019216 . obo:OBI_0002508 a rdfs:Class ; rdfs:label "sputum specimen" ; rdfs:comment "A specimen that is derived from sputum." ; rdfs:subClassOf obo:OBI_0001479 . obo:GO_0006886 a rdfs:Class ; rdfs:label "intracellular protein transport" ; rdfs:comment "The directed movement of proteins in a cell, including the movement of proteins between specific compartments or structures within a cell, such as organelles of a eukaryotic cell." ; rdfs:subClassOf obo:GO_0015031 , obo:GO_0046907 . obo:PR_000030713 a rdfs:Class ; rdfs:label "FAD-dependent oxidoreductase domain-containing protein 2" ; rdfs:comment "A protein that is a translation product of the human FOXRED2 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:CHEBI_50329 a rdfs:Class ; rdfs:label "2-carboxyethyl group" ; rdfs:subClassOf obo:CHEBI_50325 . obo:NCBITaxon_2687255 a rdfs:Class ; rdfs:label "Chalinolobus morio alphacoronavirus" ; rdfs:subClassOf obo:NCBITaxon_366617 . obo:PR_000001814 a rdfs:Class ; rdfs:label "G protein-activated inward rectifier potassium channel" ; rdfs:comment "An inwardly rectifying potassium channel protein that has core architecture consisting of an Inward rectifier potassium channel domain (Pfam:PF01007), which may be preceeded by an Inward rectifier potassium channel N-terminal domain (Pfam:PF08466)." ; rdfs:subClassOf obo:PR_000044652 . obo:NCBITaxon_2042590 a rdfs:Class ; rdfs:label "Coronavirus PREDICT CoV-66" ; rdfs:subClassOf obo:NCBITaxon_696098 . obo:UBERON_0001268 a rdfs:Class ; rdfs:label "peritoneal fluid" ; rdfs:comment "Transudate contained in the peritoneal cavity." ; rdfs:subClassOf obo:UBERON_0006314 . obo:NCBITaxon_572290 a rdfs:Class ; rdfs:label "Thrush coronavirus HKU12-600" ; rdfs:subClassOf obo:NCBITaxon_2724161 . obo:CHEBI_145499 a rdfs:Class ; rdfs:label "2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimethoxyindan-1-one" ; rdfs:comment "A member of the class of indanones that is 5,6-dimethoxyindan-1-one which is substituted at position 2 by an (N-benzylpiperidin-4-yl)methyl group." ; rdfs:subClassOf obo:CHEBI_24789 , obo:CHEBI_26151 , obo:CHEBI_35618 . obo:CIDO_0000886 a rdfs:Class ; rdfs:label "SARS-CoV2 nsp5_C145A protein binding to human TRMT1" ; rdfs:comment "SARS-CoV2 nsp5_C145A protein binding to human TRMT1, as evidented by an affinity-purification mass spectrometry experiment" ; rdfs:subClassOf obo:CIDO_0000047 . obo:VO_0005193 a rdfs:Class ; rdfs:label "COVAX-19"@en ; rdfs:comment "A SARS-CoV-2 protein subunit vaccine developed by Vaxine Pty Ltd and CinnaGen Co. and adjuvanted with Advax" ; rdfs:subClassOf obo:VO_0005269 . obo:NCBITaxon_305415 a rdfs:Class ; rdfs:label "SARS coronavirus C019" ; rdfs:subClassOf obo:NCBITaxon_694009 . obo:PR_Q13237 a rdfs:Class ; rdfs:label "cGMP-dependent protein kinase 2 (human)" ; rdfs:comment "A cGMP-dependent protein kinase 2 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000013240 , obo:PR_000029067 . obo:CHEBI_76668 a rdfs:Class ; rdfs:label "EC 2.7.* (P-containing group transferase) inhibitor" ; rdfs:comment "A transferase inhibitor that inhibits the action of a phosphorus-containing group transferase (EC 2.7.*.*)." ; rdfs:subClassOf obo:CHEBI_71300 . obo:PR_000016827 a rdfs:Class ; rdfs:label "gamma-tubulin complex component 2" ; rdfs:comment "A protein that is a translation product of the human TUBGCP2 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:CHEBI_23677 a rdfs:Class ; rdfs:label "diazole" ; rdfs:comment "An azole that is either one of a pair of heterocyclic organic compounds comprising three carbon atoms and two nitrogen atoms arranged in a ring." ; rdfs:subClassOf obo:CHEBI_68452 . obo:PR_P48549 a rdfs:Class ; rdfs:label "G protein-activated inward rectifier potassium channel 1 (human)" ; rdfs:comment "A G protein-activated inward rectifier potassium channel 1 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000002002 , obo:PR_000029067 . obo:CHEBI_35620 a rdfs:Class ; rdfs:label "vasodilator agent" ; rdfs:comment "A drug used to cause dilation of the blood vessels." ; rdfs:subClassOf obo:CHEBI_35554 . obo:UBERON_0000996 a rdfs:Class ; rdfs:label "vagina" ; rdfs:comment "A fibromuscular tubular tract leading from the uterus to the exterior of the body in female placental mammals and marsupials, or to the cloaca in female birds, monotremes, and some reptiles[WP]." ; rdfs:subClassOf obo:UBERON_0000465 . obo:NCBITaxon_2032731 a rdfs:Class ; rdfs:label "Swine acute diarrhea syndrome coronavirus" ; rdfs:subClassOf obo:NCBITaxon_2691594 . obo:GO_0071902 a rdfs:Class ; rdfs:label "positive regulation of protein serine/threonine kinase activity" ; rdfs:comment "Any process that increases the rate, frequency, or extent of protein serine/threonine kinase activity." ; rdfs:subClassOf obo:GO_0045860 , obo:GO_0071900 . obo:OBI_0002627 a rdfs:Class ; rdfs:label "ribosomal RNA-depleted RNA extract" ; rdfs:comment "An extract of RNA which is produced through rRNA (ribosomal RNA) depletion (the removal of highly abundant rRNA species)." ; rdfs:subClassOf obo:OBI_0000880 . obo:CHEBI_37957 a rdfs:Class ; rdfs:label "histaminergic drug" ; rdfs:comment "Drugs used for their actions on histaminergic systems." ; rdfs:subClassOf obo:CHEBI_35942 . obo:CIDO_0020149 a rdfs:Class ; rdfs:label "GenePro SARS-CoV-2 Test" ; rdfs:seeAlso ; rdfs:subClassOf obo:CIDO_0000454 . obo:NCBITaxon_1679912 a rdfs:Class ; rdfs:label "Coronavirus RCoV/NL_69/Mic_arv/NED/2007" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:NCBITaxon_58055 a rdfs:Class ; rdfs:label "Rhinolophidae" ; rdfs:subClassOf obo:NCBITaxon_30560 . obo:PR_000016878 a rdfs:Class ; rdfs:label "tyrosine-protein kinase receptor TYRO3" ; rdfs:comment "A protein that is a translation product of the human TYRO3 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:VO_0003154 a rdfs:Class ; rdfs:label "ISS 1018 CpG ODN vaccine adjuvant"@en ; rdfs:comment "A CpG DNA vaccine adjuvant that is a short, synthetic, unmethylated CpG oligodeoxynucleotide (CpG ODN) with immunostimulatory activity." ; rdfs:subClassOf obo:VO_0001237 . obo:CHEBI_74338 a rdfs:Class ; rdfs:label "D-valine zwitterion" ; rdfs:comment "A D-alpha-amino acid zwitterion that is D-valine in which a proton has been transferred from the carboxy group to the amino group. It is the major species at pH 7.3." ; rdfs:subClassOf obo:CHEBI_59871 . obo:PR_000014022 a rdfs:Class ; rdfs:label "receptor-interacting serine/threonine-protein kinase 1" ; rdfs:comment "A protein that is a translation product of the human RIPK1 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:PR_P41743 a rdfs:Class ; rdfs:label "protein kinase C iota type (human)" ; rdfs:comment "A protein kinase C iota type that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000013233 , obo:PR_000029067 . obo:PR_Q9C0D3 a rdfs:Class ; rdfs:label "protein zyg-11 homolog B (human)" ; rdfs:comment "A protein zyg-11 homolog B that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000018241 , obo:PR_000029067 . obo:OPMI_0000573 a rdfs:Class ; rdfs:label "quantity of drug exposure"@en ; rdfs:comment "The quantity of drug exposure refers to the number of drug pieces, e.g. tablets, that are exposed to a person." ; rdfs:subClassOf obo:IAO_0000109 . obo:GO_0005262 a rdfs:Class ; rdfs:label "calcium channel activity" ; rdfs:comment "Enables the facilitated diffusion of a calcium ion (by an energy-independent process) involving passage through a transmembrane aqueous pore or channel without evidence for a carrier-mediated mechanism." ; rdfs:subClassOf obo:GO_0005261 , obo:GO_0046873 . obo:CHEBI_35286 a rdfs:Class ; rdfs:label "iminium ion" ; rdfs:comment "Cations of structure R2C=N(+)R2." ; rdfs:subClassOf obo:CHEBI_25697 . obo:CHEBI_189655 a rdfs:Class ; rdfs:label "PS3061" ; rdfs:subClassOf obo:CHEBI_50860 . obo:CIDO_0000322 a rdfs:Class ; rdfs:label "QPTESIVRFPNITNL"@en ; rdfs:subClassOf obo:CIDO_0000314 . a rdfs:Class ; rdfs:label "Hematologic Activity Alteration [PE]" ; rdfs:subClassOf . obo:NCBITaxon_1415833 a rdfs:Class ; rdfs:label "Bat SARS-like coronavirus Rs3267-2" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:PR_000029880 a rdfs:Class ; rdfs:label "zinc finger CCCH domain-containing protein 7A" ; rdfs:comment "A protein that is a translation product of the human ZC3H7A gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:GO_0046651 a rdfs:Class ; rdfs:label "lymphocyte proliferation" ; rdfs:comment "The expansion of a lymphocyte population by cell division." ; rdfs:subClassOf obo:GO_0008283 , obo:GO_0045321 . obo:CHEBI_15603 a rdfs:Class ; rdfs:label "L-leucine" ; rdfs:comment "The L-enantiomer of leucine." ; rdfs:subClassOf obo:CHEBI_15705 , obo:CHEBI_25017 , obo:CHEBI_26463 , obo:CHEBI_83813 . obo:OGG_0000000003 a rdfs:Class ; rdfs:label "gene disposition"@en ; rdfs:comment "a disposition that a gene can be used as a blueprint for generating a new form of product such as protein. " ; rdfs:subClassOf obo:BFO_0000016 . a rdfs:Class ; rdfs:label "Cellular Transport Alteration [PE]" ; rdfs:subClassOf . obo:PR_P17612 a rdfs:Class ; rdfs:label "cAMP-dependent protein kinase catalytic subunit alpha (human)" ; rdfs:comment "A cAMP-dependent protein kinase catalytic subunit alpha that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000013222 , obo:PR_000029067 . obo:PR_P40429 a rdfs:Class ; rdfs:label "60S ribosomal protein L13a (human)" ; rdfs:comment "A 60S ribosomal protein L13a that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000014193 , obo:PR_000029067 . obo:CIDO_0000855 a rdfs:Class ; rdfs:label "SARS-CoV2 nsp13 protein binding to human PRKAR2B" ; rdfs:comment "SARS-CoV2 nsp13 protein binding to human PRKAR2B, as evidented by an affinity-purification mass spectrometry experiment" ; rdfs:subClassOf obo:CIDO_0000058 . a rdfs:Class ; rdfs:label "R [Preparations]" ; rdfs:subClassOf . obo:NCBITaxon_1649335 a rdfs:Class ; rdfs:label "Goose-dominant Coronavirus" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:CIDO_0020161 a rdfs:Class ; rdfs:label "GS COVID-19 RT-PCR Kit" ; rdfs:seeAlso ; rdfs:subClassOf obo:CIDO_0000454 . obo:CIDO_0000466 a rdfs:Class ; rdfs:label "GSALNHLTSQLRHNF" ; rdfs:comment "A coronavirus epitope that is part of some S protein from HCoV NL63 composed of the following amino acids GSALNHLTSQLRHNF" ; rdfs:subClassOf obo:CIDO_0000449 . obo:NCBITaxon_2664420 a rdfs:Class ; rdfs:label "unclassified Coronavirinae" ; rdfs:subClassOf obo:NCBITaxon_693995 . obo:CHEBI_50919 a rdfs:Class ; rdfs:label "antiemetic" ; rdfs:comment "A drug used to prevent nausea or vomiting. An antiemetic may act by a wide range of mechanisms: it might affect the medullary control centres (the vomiting centre and the chemoreceptive trigger zone) or affect the peripheral receptors." ; rdfs:subClassOf obo:CHEBI_23888 . obo:CHEBI_38481 a rdfs:Class ; rdfs:label "alkaloid ester" ; rdfs:subClassOf obo:CHEBI_22315 , obo:CHEBI_33308 . obo:PR_P09601 a rdfs:Class ; rdfs:label "heme oxygenase 1 (human)" ; rdfs:comment "A heme oxygenase 1 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000008644 , obo:PR_000029067 . obo:NCBITaxon_1679885 a rdfs:Class ; rdfs:label "Coronavirus RCoV/D_RMU10_1182/Mic_agr/GER/2010" ; rdfs:subClassOf obo:NCBITaxon_2664420 . a rdfs:Class ; rdfs:label "Pathologic Processes [Disease/Finding]" ; rdfs:subClassOf . obo:PR_Q8IY84 a rdfs:Class ; rdfs:label "serine/threonine-protein kinase NIM1 (human)" ; rdfs:comment "A serine/threonine-protein kinase NIM1 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000011211 , obo:PR_000029067 . obo:CIDO_0020074 a rdfs:Class ; rdfs:label "Childrens-Altona-SARS-CoV-2 Assay" ; rdfs:seeAlso ; rdfs:subClassOf obo:CIDO_0000454 . obo:OMIABIS_0000050 a rdfs:Class ; rdfs:label "fixed tissue specimen"@en ; rdfs:comment "A processed specimen that is the output of a fixation process."@en ; rdfs:subClassOf obo:OBI_0000953 . obo:CHEBI_37733 a rdfs:Class ; rdfs:label "EC 3.1.1.8 (cholinesterase) inhibitor" ; rdfs:comment "An EC 3.1.1.* (carboxylic ester hydrolase) inhibitor that interferes with the action of cholinesterase (EC 3.1.1.8)." ; rdfs:subClassOf obo:CHEBI_76773 . obo:CHEBI_26271 a rdfs:Class ; rdfs:label "proline" ; rdfs:comment "An alpha-amino acid that is pyrrolidine bearing a carboxy substituent at position 2." ; rdfs:subClassOf obo:CHEBI_33704 , obo:CHEBI_38260 . obo:PR_P12109 a rdfs:Class ; rdfs:label "collagen alpha-1(VI) chain (human)" ; rdfs:comment "A collagen alpha-1(VI) chain that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000003353 , obo:PR_000029067 . obo:CIDO_0020176 a rdfs:Class ; rdfs:label "Integrity Laboratories SARS-CoV-2 Assay" ; rdfs:seeAlso ; rdfs:subClassOf obo:CIDO_0000454 . obo:NCBITaxon_9443 a rdfs:Class ; rdfs:label "Primates" ; rdfs:subClassOf obo:NCBITaxon_314146 . obo:CHEBI_17102 a rdfs:Class ; rdfs:label "phosphoramide" ; rdfs:comment "A compound in which one or more of the OH groups of phosphoric acid have been replaced with an amino or substituted amino group. The term is commonly confined to the phosphoric triamides, P(=O)(NR2)3, since replacement of one or two OH groups produces phosphoramidic acids: P(=O)(OH)(NR2)2 , P(=O)(OH)2(NR2)." ; rdfs:subClassOf obo:CHEBI_33256 . obo:PR_000013233 a rdfs:Class ; rdfs:label "protein kinase C iota type" ; rdfs:comment "A protein kinase C, iota-like that is a translation product of the human PRKCI gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000045383 . obo:CIDO_0000972 a rdfs:Class ; rdfs:label "SARS-CoV2 orf3a protein binding to human ALG5" ; rdfs:comment "SARS-CoV2 orf3a protein binding to human ALG5, as evidented by an affinity-purification mass spectrometry experiment" ; rdfs:subClassOf obo:CIDO_0000584 . obo:GO_0007186 a rdfs:Class ; rdfs:label "G protein-coupled receptor signaling pathway" ; rdfs:comment "The series of molecular signals initiated by a ligand binding to its receptor, in which the activated receptor promotes the exchange of GDP for GTP on the alpha-subunit of an associated heterotrimeric G-protein complex. The GTP-bound activated alpha-G-protein then dissociates from the beta- and gamma-subunits to further transmit the signal within the cell. The pathway begins with receptor-ligand interaction, and ends with regulation of a downstream cellular process. The pathway can start from the plasma membrane, Golgi or nuclear membrane." ; rdfs:subClassOf obo:GO_0007165 . obo:CHEBI_33432 a rdfs:Class ; rdfs:label "monoatomic chlorine" ; rdfs:subClassOf obo:CHEBI_33431 , obo:CHEBI_33433 . a rdfs:Class ; rdfs:label "INTERFERON ALFA-2A" ; rdfs:subClassOf . obo:PR_000017339 a rdfs:Class ; rdfs:label "Vam6/Vps39-like protein" ; rdfs:comment "A protein that is a translation product of the human VPS39 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:CHEBI_35589 a rdfs:Class ; rdfs:label "9H-purine" ; rdfs:comment "The 9H-tautomer of purine." ; rdfs:subClassOf obo:CHEBI_35584 . obo:CIDO_0001166 a rdfs:Class ; rdfs:label "AA variant in SARS-CoV-2 S protein S2 CT region"@en ; rdfs:subClassOf obo:CIDO_0000595 . obo:CHEBI_28938 a rdfs:Class ; rdfs:label "ammonium" ; rdfs:comment "An onium cation obtained by protonation of ammonia." ; rdfs:subClassOf obo:CHEBI_35106 , obo:CHEBI_50313 , obo:CHEBI_60242 . obo:CHEBI_48946 a rdfs:Class ; rdfs:label "2-methylbutyrate" ; rdfs:subClassOf obo:CHEBI_58951 , obo:CHEBI_58956 . obo:PR_Q5VT66 a rdfs:Class ; rdfs:label "mitochondrial amidoxime-reducing component 1 (human)" ; rdfs:comment "A mitochondrial amidoxime-reducing component 1 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000010527 , obo:PR_000029067 . obo:CIDO_0000902 a rdfs:Class ; rdfs:label "SARS-CoV2 nsp7 protein binding to human LMAN2" ; rdfs:comment "SARS-CoV2 nsp7 protein binding to human LMAN2, as evidented by an affinity-purification mass spectrometry experiment" ; rdfs:subClassOf obo:CIDO_0000049 . obo:CHEBI_36838 a rdfs:Class ; rdfs:label "17-hydroxy steroid" ; rdfs:comment "A hydroxy steroid carrying a hydroxy group at position 17." ; rdfs:subClassOf obo:CHEBI_35350 . obo:NCBITaxon_398812 a rdfs:Class ; rdfs:label "TGEV virulent Purdue" ; rdfs:subClassOf obo:NCBITaxon_11151 . obo:NCIT_C17049 a rdfs:Class ; rdfs:label "Race" ; rdfs:comment "An arbitrary classification of a taxonomic group that is a division of a species. It usually arises as a consequence of geographical isolation within a species and is characterized by shared heredity, physical attributes and behavior, and in the case of humans, by common history, nationality, or geographic distribution." ; rdfs:subClassOf obo:NCIT_C17005 . obo:CIDO_0000185 a rdfs:Class ; rdfs:label "authorized clinical COVID-19 drug role"@en ; rdfs:subClassOf obo:CIDO_0000011 , obo:DRON_00000001 . obo:UBERON_0007106 a rdfs:Class ; rdfs:label "chorionic villus" ; rdfs:comment "One of the minute vascular projections of the fetal chorion that combines with maternal uterine tissue to form the placenta." ; rdfs:subClassOf obo:UBERON_0000465 . a rdfs:Class ; rdfs:label "Brain Diseases, Metabolic, Inborn [Disease/Finding]" ; rdfs:subClassOf , . obo:CIDO_0000953 a rdfs:Class ; rdfs:label "SARS-CoV2 nsp9 protein binding to human MAT2B" ; rdfs:comment "SARS-CoV2 nsp9 protein binding to human MAT2B, as evidented by an affinity-purification mass spectrometry experiment" ; rdfs:subClassOf obo:CIDO_0000583 . obo:PR_P04083 a rdfs:Class ; rdfs:label "annexin A1 (human)" ; rdfs:comment "An annexin A1 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000004071 , obo:PR_000029067 . obo:CHEBI_38147 a rdfs:Class ; rdfs:label "cardiotonic drug" ; rdfs:comment "A drug that has a strengthening effect on the heart or that can increase cardiac output." ; rdfs:subClassOf obo:CHEBI_35554 . obo:CIDO_0020131 a rdfs:Class ; rdfs:label "ePlex SARS-CoV-2 Test" ; rdfs:seeAlso ; rdfs:subClassOf obo:CIDO_0000454 . obo:CHEBI_76848 a rdfs:Class ; rdfs:label "EC 1.17.4.* (oxidoreductase acting on CH or CH2 with a disulfide as acceptor) inhibitor" ; rdfs:comment "An EC 1.17.* (oxidoreductase acting on CH or CH2) inhibitor that interferes with the activity of any such enzyme that uses a disulfide as acceptor (EC 1.17.4.*)." ; rdfs:subClassOf obo:CHEBI_76744 . obo:CHEBI_50904 a rdfs:Class ; rdfs:label "allergen" ; rdfs:comment "A chemical compound, or part thereof, which causes the onset of an allergic reaction by interacting with any of the molecular pathways involved in an allergy." ; rdfs:subClassOf obo:CHEBI_52209 . obo:PR_P52306 a rdfs:Class ; rdfs:label "Rap1 GTPase-GDP dissociation stimulator 1 (human)" ; rdfs:comment "A Rap1 GTPase-GDP dissociation stimulator 1 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000013722 , obo:PR_000029067 . obo:PR_000007001 a rdfs:Class ; rdfs:label "eukaryotic translation initiation factor 4H" ; rdfs:comment "A protein that is a translation product of the human EIF4H gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:NCBITaxon_1176035 a rdfs:Class ; rdfs:label "Alpaca respiratory coronavirus" ; rdfs:subClassOf obo:NCBITaxon_11137 . obo:PR_P07332 a rdfs:Class ; rdfs:label "tyrosine-protein kinase Fes/Fps (human)" ; rdfs:comment "A tyrosine-protein kinase Fes/Fps that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000007463 , obo:PR_000029067 . obo:CHEBI_35481 a rdfs:Class ; rdfs:label "non-narcotic analgesic" ; rdfs:comment "A drug that has principally analgesic, antipyretic and anti-inflammatory actions. Non-narcotic analgesics do not bind to opioid receptors." ; rdfs:subClassOf obo:CHEBI_35480 . obo:PR_Q96CW1 a rdfs:Class ; rdfs:label "AP-2 complex subunit mu (human)" ; rdfs:comment "An AP-2 complex subunit mu that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000004102 , obo:PR_000029067 . obo:OBI_0002545 a rdfs:Class ; rdfs:label "ileum specimen" ; rdfs:comment "A specimen that is derived from ileum." ; rdfs:subClassOf obo:OBI_0001479 . obo:PR_000003353 a rdfs:Class ; rdfs:label "collagen alpha-1(VI) chain" ; rdfs:comment "A collagen type VI alpha chain that is a translation product of the human COL6A1 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000003386 . obo:NCBITaxon_903630 a rdfs:Class ; rdfs:label "Kenya bat coronavirus BtKY92" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:NCBITaxon_1897070 a rdfs:Class ; rdfs:label "Bat coronavirus Car.per/1514/BRA/2011" ; rdfs:subClassOf obo:NCBITaxon_366617 . a rdfs:Class ; rdfs:label "Mycosis Fungoides [Disease/Finding]" ; rdfs:subClassOf . obo:NCBITaxon_681866 a rdfs:Class ; rdfs:label "Kenya bat coronavirus BtKY20" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:OBI_2000008 a rdfs:Class ; rdfs:label "semen specimen" ; rdfs:comment "A specimen that is derived from some semen" ; rdfs:subClassOf obo:OBI_0001479 . obo:NCBITaxon_756641 a rdfs:Class ; rdfs:label "Bovine coronavirus cow/WDBR-729/BRA/2003" ; rdfs:subClassOf obo:NCBITaxon_11128 . obo:NCBITaxon_1329911 a rdfs:Class ; rdfs:label "Toxicofera" ; rdfs:subClassOf obo:NCBITaxon_1329912 . obo:PR_Q04771 a rdfs:Class ; rdfs:label "activin receptor type-1 (human)" ; rdfs:comment "An activin receptor type-1 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000000067 , obo:PR_000029067 . obo:CHEBI_36915 a rdfs:Class ; rdfs:label "inorganic cation" ; rdfs:subClassOf obo:CHEBI_36914 , obo:CHEBI_36916 . obo:PR_000049764 a rdfs:Class ; rdfs:label "influenzavirus matrix protein 2" ; rdfs:comment "An influenzavirus M gene translation product that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P06821 or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000037023 . obo:UBERON_0000477 a rdfs:Class ; rdfs:label "anatomical cluster" ; rdfs:comment "Anatomical group that has its parts adjacent to one another." ; rdfs:subClassOf obo:BFO_0000040 . a rdfs:Class ; rdfs:label "Ventricular Fibrillation [Disease/Finding]" ; rdfs:subClassOf . obo:CHEBI_87631 a rdfs:Class ; rdfs:label "statin" ; rdfs:comment "Any organooxygen compound whose structure is related to compactin (mevastatin) and which may be used as an anticholesteremic drug due its EC 1.1.1.34/EC 1.1.1.88 (hydroxymethylglutaryl-CoA reductase) inhibitory properties." ; rdfs:subClassOf obo:CHEBI_36963 . obo:IDO_0000658 a rdfs:Class ; rdfs:label "host exposure to infectious agent" ; rdfs:comment "A process in which a potential host of an infectious agent is exposed to an infectious agent." ; rdfs:subClassOf obo:BFO_0000015 . obo:VO_0005172 a rdfs:Class ; rdfs:label "INO-4800"@en ; rdfs:comment "A DNA vaccine that expresses S protein from the pGX9501 vector" ; rdfs:subClassOf obo:VO_0005203 . obo:CHEBI_36862 a rdfs:Class ; rdfs:label "14beta-hydroxy steroid" ; rdfs:comment "A 14-hydroxy steroid in which the hydroxy group has a beta-configuration." ; rdfs:subClassOf obo:CHEBI_36860 . obo:DOID_778 a rdfs:Class ; rdfs:label "delusional disorder" ; rdfs:comment "A psychotic disorder that involves an uncommon psychiatric condition in which patients present with circumscribed symptoms of non-bizarre delusions, but with the absence of prominent hallucinations and no thought disorder, mood disorder, or significant flattening effect." ; rdfs:subClassOf obo:DOID_2468 . obo:CHEBI_78675 a rdfs:Class ; rdfs:label "fundamental metabolite" ; rdfs:comment "Any metabolite produced by all living cells." ; rdfs:subClassOf obo:CHEBI_25212 . obo:NCBITaxon_389141 a rdfs:Class ; rdfs:label "Bat coronavirus (BtCoV/A632/2005)" ; rdfs:subClassOf obo:NCBITaxon_389126 . obo:NCBITaxon_255194 a rdfs:Class ; rdfs:label "SARS coronavirus SoD" ; rdfs:subClassOf obo:NCBITaxon_694009 . obo:CHEBI_30768 a rdfs:Class ; rdfs:label "propionic acid" ; rdfs:comment "A short-chain saturated fatty acid comprising ethane attached to the carbon of a carboxy group." ; rdfs:subClassOf obo:CHEBI_26607 , obo:CHEBI_26666 . obo:GO_0001990 a rdfs:Class ; rdfs:label "regulation of systemic arterial blood pressure by hormone" ; rdfs:comment "The process in which hormones modulate the force with which blood passes through the circulatory system. A hormone is one of a group of substances formed in very small amounts in one specialized organ or group of cells and carried (sometimes in the bloodstream) to another organ or group of cells, in the same organism, upon which they have a specific regulatory action." ; rdfs:subClassOf obo:GO_0003008 , obo:GO_0008217 . obo:PR_Q56UN5 a rdfs:Class ; rdfs:label "mitogen-activated protein kinase kinase kinase 19 (human)" ; rdfs:comment "A mitogen-activated protein kinase kinase kinase 19 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000017548 , obo:PR_000029067 . obo:PR_000002118 a rdfs:Class ; rdfs:label "voltage-dependent P/Q-type calcium channel subunit alpha-1A" ; rdfs:comment "A voltage-gated calcium channel subunit alpha that is a translation product of the human CACNA1A gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000001974 . obo:CHEBI_52424 a rdfs:Class ; rdfs:label "EC 3.2.1.* (glycosidase) inhibitor" ; rdfs:comment "An EC 3.2.* (glycosylase) inhibitor that interferes with the action of any glycosidase (i.e. enzymes hydrolysing O- and S-glycosyl compounds, EC 3.2.1.*)." ; rdfs:subClassOf obo:CHEBI_76761 . a rdfs:Class ; rdfs:label "Benzazepines [Chemical/Ingredient]" ; rdfs:subClassOf . a rdfs:Class ; rdfs:label "Actinomycetales Infections [Disease/Finding]" ; rdfs:subClassOf . obo:CIDO_0000860 a rdfs:Class ; rdfs:label "SARS-CoV2 nsp13 protein binding to human TLE3" ; rdfs:comment "SARS-CoV2 nsp13 protein binding to human TLE3, as evidented by an affinity-purification mass spectrometry experiment" ; rdfs:subClassOf obo:CIDO_0000058 . obo:NCBITaxon_694007 a rdfs:Class ; rdfs:label "Tylonycteris bat coronavirus HKU4" ; rdfs:subClassOf obo:NCBITaxon_2509494 . obo:OPMI_0000484 a rdfs:Class ; rdfs:label "inpatient visit"@en ; rdfs:comment "A vist ocurrence in which the patient's condition requires admission to a hospital." ; rdfs:subClassOf obo:OPMI_0000482 . obo:CHEBI_77738 a rdfs:Class ; rdfs:label "(S)-verapamil(1+)" ; rdfs:comment "An ammonium ion resulting from the protonation of the tertiary amino group of (S)-verapamil." ; rdfs:subClassOf obo:CHEBI_35274 . obo:NCBITaxon_231423 a rdfs:Class ; rdfs:label "Murine coronavirus strain DVIM" ; rdfs:subClassOf obo:NCBITaxon_11138 . obo:PR_000001975 a rdfs:Class ; rdfs:label "voltage-gated sodium channel subunit alpha" ; rdfs:comment "A voltage-gated sodium channel protein that has a core architecture consisting of four similar domains (I-VI), each containing six transmembrane helices (S1-S6), with a pore loop between S5 and S6. The S4 segments contain positively charged amino acids at every third position and serve as voltage sensors. These large proteins (about 2000 amino acids) contain a unique Sodium ion transport-associated domain (Pfam:PF06512) located between two pairs of Ion transport protein domains (Pfam:PF00520). An IQ calmodulin-binding motif (Pfam:PF00612) may be found about 100 amino acids from the carboxyl end." ; rdfs:subClassOf obo:PR_000044660 . obo:CIDO_0000451 a rdfs:Class ; rdfs:label "HCoV 229E S protein epitope"@en ; rdfs:subClassOf obo:CIDO_0000409 . obo:DOID_630 a rdfs:Class ; rdfs:label "genetic disease" ; rdfs:comment "A disease that has_material_basis_in genetic variations in the human genome." ; rdfs:subClassOf obo:DOID_4 . obo:NCBITaxon_1415841 a rdfs:Class ; rdfs:label "Bat SARS-like coronavirus Rs4085" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:NCBITaxon_903603 a rdfs:Class ; rdfs:label "Kenya bat coronavirus BtKY65" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:CIDO_0020334 a rdfs:Class ; rdfs:label "Warrior Diagnostics SARS-CoV-2 Assay" ; rdfs:seeAlso ; rdfs:subClassOf obo:CIDO_0000454 . obo:OBI_0002551 a rdfs:Class ; rdfs:label "suprapubic skin specimen" ; rdfs:comment "A specimen that is derived from suprapubic skin." ; rdfs:subClassOf obo:OBI_0001479 . obo:VO_0005198 a rdfs:Class ; rdfs:label "COVID-19 RNA vaccine"@en ; rdfs:subClassOf obo:VO_0004908 . obo:PR_P07333 a rdfs:Class ; rdfs:label "macrophage colony-stimulating factor 1 receptor (human)" ; rdfs:comment "A macrophage colony-stimulating factor 1 receptor that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000002062 , obo:PR_000029067 . obo:NCBITaxon_1964809 a rdfs:Class ; rdfs:label "Coronavirus JC54" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:CIDO_0000840 a rdfs:Class ; rdfs:label "SARS-CoV2 nsp13 protein binding to human GOLGA2" ; rdfs:comment "SARS-CoV2 nsp13 protein binding to human GOLGA2, as evidented by an affinity-purification mass spectrometry experiment" ; rdfs:subClassOf obo:CIDO_0000058 . a rdfs:Class ; rdfs:label "Uterine Diseases [Disease/Finding]" ; rdfs:subClassOf . obo:NCBITaxon_1415845 a rdfs:Class ; rdfs:label "Bat SARS-like coronavirus Rs4092" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:OPMI_0000546 a rdfs:Class ; rdfs:label "secondary diagnosis status"@en ; rdfs:comment "A secondary diagnosis is a condition that coexists at the time of admission, that develops subsequently, or that affects the treatment received and/or length of stay." ; rdfs:subClassOf obo:OPMI_0000533 . obo:OAE_0002625 a rdfs:Class ; rdfs:label "local AE"@en ; rdfs:comment "an adverse event that occurs locally in a certain location. This is different from the systematci adverse event that occurs throughout the systemtic circulation." ; rdfs:subClassOf obo:OAE_0000001 . obo:PR_Q86VR2 a rdfs:Class ; rdfs:label "reticulophagy regulator 3 (human)" ; rdfs:comment "A reticulophagy regulator 3 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000029067 , obo:PR_000029462 . a rdfs:Class ; rdfs:label "Receptor Interactions [MoA]" ; rdfs:subClassOf . obo:CIDO_0000687 a rdfs:Class ; rdfs:label "Q493R in SARS-CoV-2 S protein" ; rdfs:comment "An AA mutation or AA variant that has mutated an amino acid at position 493 into a arginine in S protein." ; rdfs:subClassOf obo:CIDO_0001157 . obo:PR_000030656 a rdfs:Class ; rdfs:label "ninein-like protein" ; rdfs:comment "A protein that is a translation product of the human NINL gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:CHEBI_25000 a rdfs:Class ; rdfs:label "lactone" ; rdfs:comment "Any cyclic carboxylic ester containing a 1-oxacycloalkan-2-one structure, or an analogue having unsaturation or heteroatoms replacing one or more carbon atoms of the ring." ; rdfs:subClassOf obo:CHEBI_33308 , obo:CHEBI_35701 , obo:CHEBI_38104 . obo:PR_000035899 a rdfs:Class ; rdfs:label "GSK3-like glycogen synthase kinase" ; rdfs:comment "A protein that contains a copy of the Protein kinase (Pfam:PF00069) domain and normally functions as a non-receptor serine/threonine protein kinase that is involved in a variety of biological processes, such as developmental signalling pathways and also regulation of the cytoskeleton." ; rdfs:subClassOf obo:PR_000000001 . obo:CIDO_0000101 a rdfs:Class ; rdfs:label "interruption to MERS-CoV infection"@en ; rdfs:comment "A process that interrupts MERS-CoV viral infection in host" ; rdfs:subClassOf obo:CIDO_0000098 . obo:PR_Q9Y3A6 a rdfs:Class ; rdfs:label "transmembrane emp24 domain-containing protein 5 (human)" ; rdfs:comment "A transmembrane emp24 domain-containing protein 5 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000029067 , obo:PR_000030597 . obo:CIDO_0020023 a rdfs:Class ; rdfs:label "AMPIPROBE SARS-CoV-2 Test System" ; rdfs:seeAlso ; rdfs:subClassOf obo:CIDO_0000454 . a rdfs:Class ; rdfs:label "Decreased Metabolic Rate [PE]" ; rdfs:subClassOf . obo:CHEBI_33245 a rdfs:Class ; rdfs:label "organic fundamental parent" ; rdfs:comment "An organic fundamental parent is a structure used as a basis for substitutive names in organic nomenclature, containing, in addition to one or more hydrogen atoms, a single atom of an element, a number of atoms (alike or different) linked together to form an unbranched chain, a monocyclic or polycyclic ring system, or a ring assembly or ring/chain system." ; rdfs:subClassOf obo:CHEBI_37175 , obo:CHEBI_50860 . obo:CIDO_0000561 a rdfs:Class ; rdfs:label "CNAQEQQIYFFEGVA" ; rdfs:comment "A coronavirus epitope that is part of some S protein from HCoV HKU1 composed of the following amino acids CNAQEQQIYFFEGVA" ; rdfs:subClassOf obo:CIDO_0000409 . obo:CIDO_0000087 a rdfs:Class ; rdfs:label "host response to coronavirus infection"@en ; rdfs:comment "A coronavirus-host interaction by which the host responds to viral infection" ; rdfs:subClassOf obo:CIDO_0000084 . obo:PR_000005269 a rdfs:Class ; rdfs:label "cyclin-dependent kinase-like 1" ; rdfs:comment "A CDK2-related kinase that is a translation product of the human CDKL1 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000003270 . obo:CIDO_0000957 a rdfs:Class ; rdfs:label "SARS-CoV2 nsp9 protein binding to human NUP54" ; rdfs:comment "SARS-CoV2 nsp9 protein binding to human NUP54, as evidented by an affinity-purification mass spectrometry experiment" ; rdfs:subClassOf obo:CIDO_0000583 . obo:CHEBI_24922 a rdfs:Class ; rdfs:label "isoquinolines" ; rdfs:comment "A class of organic heteropolycyclic compound consisting of isoquinoline and its substitution derivatives." ; rdfs:subClassOf obo:CHEBI_38101 , obo:CHEBI_38166 . obo:CHEBI_32855 a rdfs:Class ; rdfs:label "D-valinate" ; rdfs:comment "The D-enantiomer of valinate." ; rdfs:subClassOf obo:CHEBI_32859 . obo:PR_000011135 a rdfs:Class ; rdfs:label "serine/threonine-protein kinase Nek9" ; rdfs:comment "A protein that is a translation product of the human NEK9 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:PR_Q76N32 a rdfs:Class ; rdfs:label "centrosomal protein of 68 kDa (human)" ; rdfs:comment "A centrosomal protein of 68 kDa that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000005354 , obo:PR_000029067 . a rdfs:Class ; rdfs:label "Eye Diseases [Disease/Finding]" ; rdfs:subClassOf . obo:CHEBI_17296 a rdfs:Class ; rdfs:label "aniline" ; rdfs:comment "A primary arylamine in which an amino functional group is substituted for one of the benzene hydrogens." ; rdfs:subClassOf obo:CHEBI_22562 , obo:CHEBI_50471 . obo:CHEBI_57932 a rdfs:Class ; rdfs:label "D-methionine zwitterion" ; rdfs:comment "Zwitterionic form of D-methionine arising from transfer of a proton from the carboxy to the amino group; major species at pH 7.3." ; rdfs:subClassOf obo:CHEBI_64558 . obo:CHEBI_26249 a rdfs:Class ; rdfs:label "prenyl groups" ; rdfs:subClassOf obo:CHEBI_33248 . obo:OBI_0002507 a rdfs:Class ; rdfs:label "saliva specimen" ; rdfs:comment "A specimen that is derived from saliva." ; rdfs:subClassOf obo:OBI_0001479 . obo:CIDO_0001035 a rdfs:Class ; rdfs:label "PF-07304814" ; rdfs:subClassOf obo:CHEBI_23367 . obo:PR_000029289 a rdfs:Class ; rdfs:label "polyamine-transporting ATPase 13A3" ; rdfs:comment "A protein that is a translation product of the human ATP13A3 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:OAE_0000600 a rdfs:Class ; rdfs:label "nausea AE" ; rdfs:comment "an abnormal digestion AE which has an outcome of nausea, a gastric discomfort associated with the inclination to vomit"@en ; rdfs:subClassOf obo:OAE_0000554 . obo:PR_000044655 a rdfs:Class ; rdfs:label "potassium channel protein" ; rdfs:comment "A voltage-gated ion channel protein that has potassium channel activity. A potassium channel enables the facilitated diffusion of a potassium ion (by an energy-independent process) involving passage through a transmembrane aqueous pore or channel without evidence for a carrier-mediated mechanism." ; rdfs:subClassOf obo:PR_000044628 . obo:PR_000012684 a rdfs:Class ; rdfs:label "phosphatidylinositol 4-kinase beta" ; rdfs:comment "A protein that is a translation product of the human PI4KB gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:NCBITaxon_33732 a rdfs:Class ; rdfs:label "Canine enteric coronavirus K378" ; rdfs:subClassOf obo:NCBITaxon_11153 . obo:NCBITaxon_1503290 a rdfs:Class ; rdfs:label "Alphacoronavirus BtMs-AlphaCoV/GS2013" ; rdfs:subClassOf obo:NCBITaxon_2501926 . obo:NCBITaxon_681880 a rdfs:Class ; rdfs:label "Kenya bat coronavirus BtKY36" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:VO_0005404 a rdfs:Class ; rdfs:label "VXS-1223"@en ; rdfs:comment "A SARS-CoV-2 protein subunit vaccine manufactured by Vaxxas Pty Ltd" ; rdfs:subClassOf obo:VO_0005202 . obo:HP_0011717 a rdfs:Class ; rdfs:label "Atrioventricular reentrant tachycardia" ; rdfs:comment "Accessory pathway-related atrioventricular reentrant tachycardia (AVRT) involves an abnormal electrical conduction of the accessory pathway. The accessory pathway connecting impulses between the atrium and the ventricle can be seen at any site in the AV groove." ; rdfs:subClassOf obo:HP_0011687 . obo:NCBITaxon_2664183 a rdfs:Class ; rdfs:label "unclassified Merbecovirus" ; rdfs:subClassOf obo:NCBITaxon_2509494 . obo:PR_000044666 a rdfs:Class ; rdfs:label "ionotropic glutamate receptor protein" ; rdfs:comment "A ligand-gated ion channel protein that is a translation product of the human GRIA1, GRIA2, GRIA3, GRIA4, GRID1, GRID2, GRIK1, GRIK2, GRIK3, GRIK4, GRIK5, GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D, GRIN3A, or GRIN3B genes, 1:1 orthologs thereof, or a semi-ortholog thereof." ; rdfs:subClassOf obo:PR_000044671 . obo:OPMI_0000492 a rdfs:Class ; rdfs:label "preceding visit occurrence"@en ; rdfs:comment "A visit occurrence that occurs for the person prior to the given visit. There could be a few days or a few years in between." ; rdfs:subClassOf obo:OPMI_0000482 . obo:OBI_0002518 a rdfs:Class ; rdfs:label "prostate gland specimen" ; rdfs:comment "A specimen that is derived from prostate gland." ; rdfs:subClassOf obo:OBI_0001479 . obo:CHEBI_83410 a rdfs:Class ; rdfs:label "alpha-amino acid ester(1+)" ; rdfs:comment "A primary ammonium ion obtained by protonation of the amino group of any alpha-amino acid ester; major species at pH 7.3." ; rdfs:subClassOf obo:CHEBI_65296 . obo:GO_0042571 a rdfs:Class ; rdfs:label "immunoglobulin complex, circulating" ; rdfs:comment "An immunoglobulin complex that is secreted into extracellular space and found in mucosal areas or other tissues or circulating in the blood or lymph. In its canonical form, a circulating immunoglobulin complex is composed of two identical heavy chains and two identical light chains, held together by disulfide bonds. Some forms of are polymers of the basic structure and contain additional components such as J-chain and the secretory component." ; rdfs:subClassOf obo:GO_0019814 , obo:OBI_1110022 . obo:CHEBI_76938 a rdfs:Class ; rdfs:label "EC 3.6.4.* (hydrolases acting on ATP; involved in cellular and subcellular movement) inhibitor" ; rdfs:comment "An EC 3.6.* (hydrolases acting on acid anhydrides) inhibitor that interferes with the action of any such enzyme acting on ATP and involved in cellular and subcellular movement (EC 3.6.4.*)." ; rdfs:subClassOf obo:CHEBI_73216 . obo:OBI_0002522 a rdfs:Class ; rdfs:label "adrenal gland specimen" ; rdfs:comment "A specimen that is derived from adrenal gland." ; rdfs:subClassOf obo:OBI_0001479 . a rdfs:Class ; rdfs:label "Decreased Parasympathetic Activity [PE]" ; rdfs:subClassOf . a rdfs:Class ; rdfs:label "Venous Thrombosis [Disease/Finding]" ; rdfs:subClassOf . obo:NCBITaxon_2727857 a rdfs:Class ; rdfs:label "unclassified Minacovirus" ; rdfs:subClassOf obo:NCBITaxon_2509496 . obo:DRON_00050843 a rdfs:Class ; rdfs:label "Cetylpyridinium Chloride 1 MG/ML / zinc chloride 0.5 MG/ML Mouthwash" ; rdfs:subClassOf obo:DRON_00031258 . obo:NCBITaxon_249080 a rdfs:Class ; rdfs:label "SARS coronavirus HSZ-Cc" ; rdfs:subClassOf obo:NCBITaxon_694009 . obo:NCBITaxon_2748374 a rdfs:Class ; rdfs:label "Tadarida brasiliensis coronavirus" ; rdfs:subClassOf obo:NCBITaxon_1986197 . obo:PR_P36888 a rdfs:Class ; rdfs:label "receptor-type tyrosine-protein kinase FLT3 (human)" ; rdfs:comment "A receptor-type tyrosine-protein kinase FLT3 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000002001 , obo:PR_000029067 . obo:HP_0004395 a rdfs:Class ; rdfs:label "Malnutrition" ; rdfs:subClassOf obo:HP_0011458 . a rdfs:Class ; rdfs:label "Gastrointestinal Neoplasms [Disease/Finding]" ; rdfs:subClassOf , . obo:CIDO_0000967 a rdfs:Class ; rdfs:label "SARS-CoV2 orf10 protein binding to human PPT1" ; rdfs:comment "SARS-CoV2 orf10 protein binding to human PPT1, as evidented by an affinity-purification mass spectrometry experiment" ; rdfs:subClassOf obo:CIDO_0000050 . obo:CHEBI_27897 a rdfs:Class ; rdfs:label "tryptophan" ; rdfs:comment "An alpha-amino acid that is alanine bearing an indol-3-yl substituent at position 3." ; rdfs:subClassOf obo:CHEBI_26167 , obo:CHEBI_33704 , obo:CHEBI_33856 , obo:CHEBI_38631 . obo:HP_0002039 a rdfs:Class ; rdfs:label "Anorexia" ; rdfs:comment "A lack or loss of appetite for food (as a medical condition)." ; rdfs:subClassOf obo:HP_0011458 . obo:BFO_0000001 a rdfs:Class ; rdfs:label "entity" . obo:CHEBI_30363 a rdfs:Class ; rdfs:label "isobutane" ; rdfs:comment "An alkane that is propane substituted by a methyl group at position 2." ; rdfs:subClassOf obo:CHEBI_138675 , obo:CHEBI_18310 . obo:DOID_594 a rdfs:Class ; rdfs:label "panic disorder" ; rdfs:comment "An anxiety disorder that is characterized by unexpected and repeated episodes of intense fear accompanied by physical symptoms that may include chest pain, heart palpitations, shortness of breath, dizziness, or abdominal distress." ; rdfs:subClassOf obo:DOID_2030 . obo:CHEBI_33860 a rdfs:Class ; rdfs:label "aromatic amine" ; rdfs:comment "An amino compound in which the amino group is linked directly to an aromatic system." ; rdfs:subClassOf obo:CHEBI_33659 , obo:CHEBI_50047 . obo:PR_P35556 a rdfs:Class ; rdfs:label "fibrillin-2 (human)" ; rdfs:comment "A fibrillin-2 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000007363 , obo:PR_000029067 . obo:HP_0012393 a rdfs:Class ; rdfs:label "Allergy" ; rdfs:comment "An allergy is an immune response or reaction to substances that are usually not harmful." ; rdfs:subClassOf obo:HP_0100326 . obo:PR_000015743 a rdfs:Class ; rdfs:label "serine/threonine-protein kinase 17A" ; rdfs:comment "A protein that is a translation product of the human STK17A gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . a rdfs:Class ; rdfs:label "DNA Integrity Alteration [PE]" ; rdfs:subClassOf . a rdfs:Class ; rdfs:label "Cytokines [Chemical/Ingredient]" ; rdfs:subClassOf . obo:NCBITaxon_742004 a rdfs:Class ; rdfs:label "Bat SARS coronavirus HKU3-7" ; rdfs:subClassOf obo:NCBITaxon_442736 . obo:VO_0005187 a rdfs:Class ; rdfs:label "COVI-VAC"@en ; rdfs:comment "A SARS-CoV-2 live, attenuated vaccine manufactured by Codagenix, Inc." ; rdfs:subClassOf obo:VO_0005204 . obo:CIDO_0000801 a rdfs:Class ; rdfs:label "SARS-CoV2 nsp10 protein binding to human GRPEL1" ; rdfs:comment "SARS-CoV2 nsp10 protein binding to human GRPEL1, as evidented by an affinity-purification mass spectrometry experiment" ; rdfs:subClassOf obo:CIDO_0000064 . obo:PR_000001907 a rdfs:Class ; rdfs:label "platelet glycoprotein Ib alpha chain" ; rdfs:comment "A protein that is a translation product of the human GP1BA gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:CHEBI_77194 a rdfs:Class ; rdfs:label "EC 2.7.1.33 (pantothenate kinase) inhibitor" ; rdfs:comment "An EC 2.7.1.* (phosphotransferases with an alcohol group as acceptor) inhibitor that interferes with the action of pantothenate kinase (EC 2.7.1.33)." ; rdfs:subClassOf obo:CHEBI_76881 . obo:CHEBI_51144 a rdfs:Class ; rdfs:label "nitrogen group" ; rdfs:subClassOf obo:CHEBI_24433 . obo:OPMI_0000508 a rdfs:Class ; rdfs:label "procedure start date"@en ; rdfs:comment "The date when a procedure starts" ; rdfs:subClassOf obo:OPMI_0000507 . obo:PR_000044630 a rdfs:Class ; rdfs:label "corticotropin-releasing factor receptor" ; rdfs:comment "A secretin-like G-protein coupled receptor that is a translation product of the human CRHR1 or CRHR2 genes, 1:1 orthologs thereof, or a semi-ortholog thereof." ; rdfs:subClassOf obo:PR_000001095 . obo:VO_0005113 a rdfs:Class ; rdfs:label "SARS MVA/S vaccine" ; rdfs:comment "A SARS recombinant vector vaccine made from a recombinant form of the highly attenuated modified vaccinia virus Ankara (MVA) containing the gene encoding full-length SARS-CoV S" ; rdfs:subClassOf obo:VO_0012183 . obo:NCBITaxon_389163 a rdfs:Class ; rdfs:label "Bat coronavirus (BtCoV/A957/2005)" ; rdfs:subClassOf obo:NCBITaxon_389126 . a rdfs:Class ; rdfs:label "Pregnenes [Chemical/Ingredient]" ; rdfs:subClassOf . obo:OGG_3043740568 a rdfs:Class ; rdfs:label "S gene of severe acute respiratory syndrome coronavirus 2" ; rdfs:subClassOf obo:OGG_2002697049 . obo:GO_0003083 a rdfs:Class ; rdfs:label "negative regulation of renal output by angiotensin" ; rdfs:comment "The process in which angiotensin directly decreases the rate of natriuresis and diuresis in the kidney." ; rdfs:subClassOf obo:GO_0002019 , obo:GO_0008217 . obo:PR_P51955 a rdfs:Class ; rdfs:label "serine/threonine-protein kinase Nek2 (human)" ; rdfs:comment "A serine/threonine-protein kinase Nek2 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000011128 , obo:PR_000029067 . obo:CHEBI_38530 a rdfs:Class ; rdfs:label "quinazolines" ; rdfs:comment "Any organic heterobicyclic compound based on a quinazoline skeleton and its substituted derivatives." ; rdfs:subClassOf obo:CHEBI_27171 , obo:CHEBI_38101 . obo:GO_0003824 a rdfs:Class ; rdfs:label "catalytic activity" ; rdfs:comment "Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic." ; rdfs:subClassOf obo:GO_0003674 . obo:NCBITaxon_31627 a rdfs:Class ; rdfs:label "Avian infectious bronchitis virus (strain UK/142/86)" ; rdfs:subClassOf obo:NCBITaxon_11120 . a rdfs:Class ; rdfs:label "Acne Vulgaris [Disease/Finding]" ; rdfs:subClassOf , . obo:PR_000003270 a rdfs:Class ; rdfs:label "CDK2-related kinase" ; rdfs:comment "A protein that is cyclin-dependent kinase. The activated form phosphorylates target substrates on Ser or Thr residues followed by a proline. The core domain architecture consists of a copy of the Protein kinase domain (Pfam:PF00069)." ; rdfs:subClassOf obo:PR_000000001 . obo:NCBITaxon_1770168 a rdfs:Class ; rdfs:label "Alpaca coronavirus" ; rdfs:subClassOf obo:NCBITaxon_696098 . obo:CIDO_0000968 a rdfs:Class ; rdfs:label "SARS-CoV2 orf10 protein binding to human RBX1" ; rdfs:comment "SARS-CoV2 orf10 protein binding to human RBX1, as evidented by an affinity-purification mass spectrometry experiment" ; rdfs:subClassOf obo:CIDO_0000050 . obo:CIDO_0020138 a rdfs:Class ; rdfs:label "Express Gene 2019-nCoV RT-PCR Diagnostic Panel" ; rdfs:seeAlso ; rdfs:subClassOf obo:CIDO_0000454 . obo:CHEBI_52210 a rdfs:Class ; rdfs:label "pharmacological role" ; rdfs:comment "A biological role which describes how a drug interacts within a biological system and how the interactions affect its medicinal properties." ; rdfs:subClassOf obo:CHEBI_24432 . obo:PR_000011524 a rdfs:Class ; rdfs:label "nuclear pore complex protein Nup88" ; rdfs:comment "A protein that is a translation product of the human NUP88 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:CHEBI_16998 a rdfs:Class ; rdfs:label "D-phenylalanine" ; rdfs:comment "The D-enantiomer of phenylalanine." ; rdfs:subClassOf obo:CHEBI_16733 , obo:CHEBI_28044 . obo:CIDO_0020232 a rdfs:Class ; rdfs:label "PerkinElmer New Coronavirus Nucleic Acid Detection Kit" ; rdfs:seeAlso ; rdfs:subClassOf obo:CIDO_0000454 . obo:CIDO_0001028 a rdfs:Class ; rdfs:label "Rexin G" ; rdfs:subClassOf obo:CHEBI_23367 . obo:PR_000004688 a rdfs:Class ; rdfs:label "[3-methyl-2-oxobutanoate dehydrogenase [lipoamide]] kinase, mitochondrial" ; rdfs:comment "A protein that is a translation product of the human BCKDK gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:OGG_1002697049 a rdfs:Class ; rdfs:label "genome of severe acute respiratory syndrome coronavirus 2" ; rdfs:comment "A coronavirus genome that belongs to a virus that has NCBI Taxonomy ID of 2697079." ; rdfs:subClassOf obo:OGG_0000000001 , obo:OGG_100011118 . obo:CHEBI_64459 a rdfs:Class ; rdfs:label "biaryl" ; rdfs:comment "An organic aromatic compound whose structure contains two aromatic rings or ring systems, joined to each other by a single bond." ; rdfs:subClassOf obo:CHEBI_33659 . obo:CHEBI_38670 a rdfs:Class ; rdfs:label "pyrrolopyrimidine" ; rdfs:subClassOf obo:CHEBI_27171 , obo:CHEBI_38101 . obo:PR_Q7Z4H8 a rdfs:Class ; rdfs:label "protein O-glucosyltransferase 3 (human)" ; rdfs:comment "A protein O-glucosyltransferase 3 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000029067 , obo:PR_000029578 . obo:PR_000003201 a rdfs:Class ; rdfs:label "calcium/calmodulin-dependent protein kinase type II subunit delta" ; rdfs:comment "A calcium/calmodulin-dependent protein kinase type II chain that is a translation product of the human CAMK2D gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000003197 . obo:DRON_00031258 a rdfs:Class ; rdfs:label "Cetylpyridinium / zinc chloride Mouthwash" ; rdfs:subClassOf obo:DRON_00000005 . a rdfs:Class ; rdfs:label "Ritonavir [Chemical/Ingredient]" ; rdfs:subClassOf . obo:NCBITaxon_749432 a rdfs:Class ; rdfs:label "Pintail coronavirus PBA-25" ; rdfs:subClassOf obo:NCBITaxon_749416 . obo:CHEBI_36358 a rdfs:Class ; rdfs:label "polyatomic ion" ; rdfs:comment "An ion consisting of more than one atom." ; rdfs:subClassOf obo:CHEBI_24870 , obo:CHEBI_36357 . obo:NCBITaxon_903614 a rdfs:Class ; rdfs:label "Kenya bat coronavirus BtKY76" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:NCBITaxon_756640 a rdfs:Class ; rdfs:label "Bovine coronavirus cow/WDBR-96/BRA/2003" ; rdfs:subClassOf obo:NCBITaxon_11128 . obo:CHEBI_48219 a rdfs:Class ; rdfs:label "disinfectant" ; rdfs:comment "An antimicrobial agent that is applied to non-living objects to destroy harmful microorganisms or to inhibit their activity." ; rdfs:subClassOf obo:CHEBI_33281 . obo:PR_000005434 a rdfs:Class ; rdfs:label "charged multivesicular body protein 2a" ; rdfs:comment "A protein that is a translation product of the human CHMP2A gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:CIDO_0000448 a rdfs:Class ; rdfs:label "spike glycoprotein (HCoV HKU1)"@en ; rdfs:comment "A surface glycoprotein of human coronavirus HKU1." ; rdfs:subClassOf obo:CIDO_0000443 . obo:NCBITaxon_1508220 a rdfs:Class ; rdfs:label "Bat coronavirus" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:CHEBI_38831 a rdfs:Class ; rdfs:label "2-benzofurans" ; rdfs:subClassOf obo:CHEBI_35259 . obo:PR_000002998 a rdfs:Class ; rdfs:label "tyrosine-protein kinase Lck" ; rdfs:comment "A proto-oncogene SRC-like tyrosine-protein kinase that is a translation product of the human LCK gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000002997 . obo:NCBITaxon_864608 a rdfs:Class ; rdfs:label "Bat coronavirus BNM98-30/BGR/2008" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:CIDO_0000570 a rdfs:Class ; rdfs:label "QQVDRLITGRLAALN" ; rdfs:comment "A coronavirus epitope that is part of some S protein from HCoV NL63 composed of the following amino acids QQVDRLITGRLAALN" ; rdfs:subClassOf obo:CIDO_0000449 . obo:CIDO_0001149 a rdfs:Class ; rdfs:label "SARS-CoV-2 pp1ab protein amino acid deletion"@en ; rdfs:subClassOf obo:CIDO_0000614 . obo:GO_1904407 a rdfs:Class ; rdfs:label "positive regulation of nitric oxide metabolic process" ; rdfs:comment "Any process that activates or increases the frequency, rate or extent of nitric oxide metabolic process." ; rdfs:subClassOf obo:GO_0051173 , obo:GO_0080164 . obo:CHEBI_86426 a rdfs:Class ; rdfs:label "triazole antifungal agent" ; rdfs:comment "A member of the class of triazole that has significant antifungal properties." ; rdfs:subClassOf obo:CHEBI_35727 . obo:CIDO_0000952 a rdfs:Class ; rdfs:label "SARS-CoV2 nsp9 protein binding to human GTF2F2" ; rdfs:comment "SARS-CoV2 nsp9 protein binding to human GTF2F2, as evidented by an affinity-purification mass spectrometry experiment" ; rdfs:subClassOf obo:CIDO_0000583 . obo:NCBITaxon_9606 a rdfs:Class ; rdfs:label "Homo sapiens" ; rdfs:subClassOf obo:NCBITaxon_2759 , obo:NCBITaxon_314146 , obo:NCBITaxon_9526 , obo:NCBITaxon_9605 . obo:NCBITaxon_389138 a rdfs:Class ; rdfs:label "Bat coronavirus (BtCoV/A619/2005)" ; rdfs:subClassOf obo:NCBITaxon_389126 . obo:CIDO_0000550 a rdfs:Class ; rdfs:label "SSATDAIIAVELLLL" ; rdfs:comment "A coronavirus epitope that is part of some S protein from HCoV NL63 composed of the following amino acids SSATDAIIAVELLLL" ; rdfs:subClassOf obo:CIDO_0000449 . obo:CHEBI_59118 a rdfs:Class ; rdfs:label "perazine" ; rdfs:comment "A phenothiazine derivative in which 10H-phenothiazinecarries a 3-(4-methylpiperazin-1-yl)propyl substituent at the N-10 position." ; rdfs:subClassOf obo:CHEBI_38093 , obo:CHEBI_46845 , obo:CHEBI_46920 . obo:CHEBI_33285 a rdfs:Class ; rdfs:label "heteroorganic entity" ; rdfs:comment "A heteroorganic entity is an organic molecular entity in which carbon atoms or organic groups are bonded directly to one or more heteroatoms." ; rdfs:subClassOf obo:CHEBI_50860 . obo:CHEBI_35715 a rdfs:Class ; rdfs:label "nitro compound" ; rdfs:comment "A compound having a nitro group, -NO2 (free valence on nitrogen), which may be attached to carbon, nitrogen (as in nitramines), or oxygen (as in nitrates), among other elements (in the absence of specification, C-nitro compounds are usually implied)." ; rdfs:subClassOf obo:CHEBI_51143 . obo:CHEBI_71420 a rdfs:Class ; rdfs:label "phenazopyridine(1+)" ; rdfs:comment "An organic cation that is the conjugate acid of phenazopyridine." ; rdfs:subClassOf obo:CHEBI_25697 , obo:CHEBI_35274 . obo:OBI_0600038 a rdfs:Class ; rdfs:label "addition of molecular label"@en ; rdfs:comment "a material processing technique intended to add a molecular label to some input material entity, to allow detection of the molecular target of this label in a detection of molecular label assay"@en ; rdfs:subClassOf obo:OBI_0000094 . obo:CHEBI_23449 a rdfs:Class ; rdfs:label "cyclic peptide" ; rdfs:subClassOf obo:CHEBI_16670 . obo:NCBITaxon_384348 a rdfs:Class ; rdfs:label "Human coronavirus NO/0733/05" ; rdfs:subClassOf obo:NCBITaxon_384335 . obo:CHEBI_62932 a rdfs:Class ; rdfs:label "mycophenolate" ; rdfs:comment "A monocarboxylic acid anion resulting from the removal of a proton from the carboxy group of mycophenolic acid." ; rdfs:subClassOf obo:CHEBI_35757 . obo:CHEBI_48676 a rdfs:Class ; rdfs:label "fibrin modulating drug" ; rdfs:comment "A drug that affects the function of fibrin in blood coagulation." ; rdfs:subClassOf obo:CHEBI_23888 . obo:GO_2000147 a rdfs:Class ; rdfs:label "positive regulation of cell motility" ; rdfs:comment "Any process that activates or increases the frequency, rate or extent of cell motility." ; rdfs:subClassOf obo:GO_0040017 , obo:GO_0051272 , obo:GO_2000145 . obo:PR_Q7Z3B4 a rdfs:Class ; rdfs:label "nucleoporin p54 (human)" ; rdfs:comment "A nucleoporin p54 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000011520 , obo:PR_000029067 . obo:GO_0008344 a rdfs:Class ; rdfs:label "adult locomotory behavior" ; rdfs:comment "Locomotory behavior in a fully developed and mature organism." ; rdfs:subClassOf obo:GO_0007626 , obo:GO_0030534 . obo:CIDO_0020202 a rdfs:Class ; rdfs:label "MGH COVID-19 qPCR assay 1" ; rdfs:seeAlso ; rdfs:subClassOf obo:CIDO_0000454 . obo:CIDO_0020063 a rdfs:Class ; rdfs:label "Bio-Speedy Direct RT-qPCR SARS-CoV-2" ; rdfs:seeAlso ; rdfs:subClassOf obo:CIDO_0000454 . obo:CHEBI_18059 a rdfs:Class ; rdfs:label "lipid" ; rdfs:comment "'Lipids' is a loosely defined term for substances of biological origin that are soluble in nonpolar solvents. They consist of saponifiable lipids, such as glycerides (fats and oils) and phospholipids, as well as nonsaponifiable lipids, principally steroids." ; rdfs:subClassOf obo:CHEBI_50860 . obo:CHEBI_17895 a rdfs:Class ; rdfs:label "L-tyrosine" ; rdfs:comment "An optically active form of tyrosine having L-configuration." ; rdfs:subClassOf obo:CHEBI_15705 , obo:CHEBI_18186 , obo:CHEBI_73690 , obo:CHEBI_83813 . obo:NCBITaxon_9674 a rdfs:Class ; rdfs:label "Paguma" ; rdfs:subClassOf obo:NCBITaxon_219112 . obo:DOID_0070091 a rdfs:Class ; rdfs:label "schizophrenia 15" ; rdfs:comment "A schizophrenia that has_material_basis_in a mutation of SHANK3 on chromosome 22q13.33." ; rdfs:subClassOf obo:DOID_0050736 , obo:DOID_5419 . obo:CIDO_0000769 a rdfs:Class ; rdfs:label "SARS-CoV2 M protein binding to human SLC30A7" ; rdfs:comment "SARS-CoV2 M protein binding to human SLC30A7, as evidented by an affinity-purification mass spectrometry experiment" ; rdfs:subClassOf obo:CIDO_0000055 . obo:NCBITaxon_1429856 a rdfs:Class ; rdfs:label "Betacoronavirus Pipistrellus kuhlii/Italy/206645-27/2011" ; rdfs:subClassOf obo:NCBITaxon_696098 . obo:HP_0006505 a rdfs:Class ; rdfs:label "Abnormality of limb epiphysis morphology" ; rdfs:comment "An anomaly of one or more epiphyses of a limb." ; rdfs:subClassOf obo:HP_0002813 , obo:HP_0011844 . obo:CHEBI_180988 a rdfs:Class ; rdfs:label "Apicidin C" ; rdfs:subClassOf obo:CHEBI_25676 . obo:CHEBI_33461 a rdfs:Class ; rdfs:label "phosphorus oxoanion" ; rdfs:subClassOf obo:CHEBI_24834 , obo:CHEBI_26082 , obo:CHEBI_33459 . obo:NCBITaxon_931892 a rdfs:Class ; rdfs:label "Alphacoronavirus Eptesicus fuscus/Appalachian Ridge/P1-C1148/IT/USA/2009" ; rdfs:subClassOf obo:NCBITaxon_366617 . obo:PR_000011474 a rdfs:Class ; rdfs:label "NUAK family SNF1-like kinase 2" ; rdfs:comment "A protein that is a translation product of the human NUAK2 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:CHEBI_146178 a rdfs:Class ; rdfs:label "6-methoxy-11-methyl-1,3,4,9,10,10a-hexahydro-2H-10,4a-(epiminoethano)phenanthrene" ; rdfs:comment "An organic heterotetracyclic compound that is 1,3,4,9,10,10a-hexahydro-2H-10,4a-(epiminoethano)phenanthrene which is substituted by a methoxy group at position 6 and a methyl group at position 11." ; rdfs:subClassOf obo:CHEBI_25418 , obo:CHEBI_35618 , obo:CHEBI_38163 , obo:CHEBI_83818 . obo:UBERON_0001134 a rdfs:Class ; rdfs:label "skeletal muscle tissue" ; rdfs:comment "Muscle tissue that consists primarily of skeletal muscle fibers." ; rdfs:subClassOf obo:UBERON_0000479 , obo:UBERON_0002385 . a rdfs:Class ; rdfs:label "Stimulate Breast Glandular Development [PE]" ; rdfs:subClassOf . obo:CHEBI_76823 a rdfs:Class ; rdfs:label "EC 6.3.1.* (acid-ammonia/amine ligase) inhibitor" ; rdfs:comment "An EC 6.3.* (C-N bond-forming ligase) inhibitor that interferes with the action of any acid-ammonia (or amine) ligase (EC 6.3.1.*)." ; rdfs:subClassOf obo:CHEBI_75600 . obo:PR_000013085 a rdfs:Class ; rdfs:label "peptidyl-prolyl cis-trans isomerase-like 3" ; rdfs:comment "A protein that is a translation product of the human PPIL3 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:NCBITaxon_864606 a rdfs:Class ; rdfs:label "Bat coronavirus BM98-65/BGR/2008" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:CHEBI_38462 a rdfs:Class ; rdfs:label "EC 3.1.1.7 (acetylcholinesterase) inhibitor" ; rdfs:comment "An EC 3.1.1.* (carboxylic ester hydrolase) inhibitor that interferes with the action of enzyme acetylcholinesterase (EC 3.1.1.7), which helps breaking down of acetylcholine into choline and acetic acid." ; rdfs:subClassOf obo:CHEBI_76773 . obo:CIDO_0000538 a rdfs:Class ; rdfs:label "NNTDSIVIGGVTYQL" ; rdfs:comment "A coronavirus epitope that is part of some S protein from HCoV NL63 composed of the following amino acids NNTDSIVIGGVTYQL" ; rdfs:subClassOf obo:CIDO_0000449 . obo:CHEBI_63353 a rdfs:Class ; rdfs:label "disaccharide derivative" ; rdfs:comment "A carbohydrate derivative that is formally obtained from a disaccharide." ; rdfs:subClassOf obo:CHEBI_63299 . obo:CIDO_0000231 a rdfs:Class ; rdfs:label "SARS-CoV-2 clade L virus"@en ; rdfs:comment "Clade L is the reference genome that was found at the beginning of the COVID-19 pandemic (December 2019)." ; rdfs:subClassOf obo:CIDO_0000405 . obo:NCBITaxon_270642 a rdfs:Class ; rdfs:label "Human group 1 coronavirus associated with pneumonia" ; rdfs:subClassOf obo:NCBITaxon_277944 . obo:CHEBI_37932 a rdfs:Class ; rdfs:label "phenothiazine" ; rdfs:subClassOf obo:CHEBI_36416 , obo:CHEBI_38093 . obo:VO_0005107 a rdfs:Class ; rdfs:label "Salmonella-tPA-S SARS DNA vaccine" ; rdfs:comment "A SARS DNA vaccine made from CTLA4HingeSARS800 DNA with SARS-CoV S protein" ; rdfs:subClassOf obo:VO_0012183 . obo:CIDO_0000929 a rdfs:Class ; rdfs:label "SARS-CoV2 nsp8 protein binding to human EXOSC5" ; rdfs:comment "SARS-CoV2 nsp8 protein binding to human EXOSC5, as evidented by an affinity-purification mass spectrometry experiment" ; rdfs:subClassOf obo:CIDO_0000582 . obo:CHEBI_38070 a rdfs:Class ; rdfs:label "anti-arrhythmia drug" ; rdfs:comment "A drug used for the treatment or prevention of cardiac arrhythmias. Anti-arrhythmia drugs may affect the polarisation-repolarisation phase of the action potential, its excitability or refractoriness, or impulse conduction or membrane responsiveness within cardiac fibres." ; rdfs:subClassOf obo:CHEBI_35554 . obo:NCBITaxon_1480113 a rdfs:Class ; rdfs:label "Mystacina coronavirus New Zealand/2013" ; rdfs:subClassOf obo:NCBITaxon_366617 . a rdfs:Class ; rdfs:label "Mansonelliasis [Disease/Finding]" ; rdfs:subClassOf . a rdfs:Class ; rdfs:label "Striated Muscle Anabolism Alteration [PE]" ; rdfs:subClassOf . obo:PR_P10613 a rdfs:Class ; rdfs:label "lanosterol 14-alpha demethylase (Candida albicans SC5314)" ; rdfs:comment "A protein that is a translation product of the ERG11 gene in Candida albicans SC5314." ; rdfs:subClassOf obo:PR_000036194 . obo:NCBITaxon_903577 a rdfs:Class ; rdfs:label "Kenya bat coronavirus BtKY109" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:OPMI_0000457 a rdfs:Class ; rdfs:label "diagnostic biomarker"@en ; rdfs:comment "A biomarker that can serve a role in narrowing down diagnosis, which can lead to diagnosis that is significantly more specific to individual patients." ; rdfs:subClassOf obo:OPMI_0000445 . obo:CHEBI_64049 a rdfs:Class ; rdfs:label "food acidity regulator" ; rdfs:comment "A food additive that is used to change or otherwise control the acidity or alkalinity of foods. They may be acids, bases, neutralising agents or buffering agents." ; rdfs:subClassOf obo:CHEBI_64047 . obo:GO_0010863 a rdfs:Class ; rdfs:label "positive regulation of phospholipase C activity" ; rdfs:comment "Any process that increases the rate of phospholipase C activity." ; rdfs:subClassOf obo:GO_0010517 , obo:GO_0010518 . obo:NCBITaxon_461305 a rdfs:Class ; rdfs:label "Rocky Mountain Bat Coronavirus 27" ; rdfs:subClassOf obo:NCBITaxon_366617 . obo:CHEBI_17792 a rdfs:Class ; rdfs:label "organohalogen compound" ; rdfs:comment "A compound containing at least one carbon-halogen bond (where X is a halogen atom)." ; rdfs:subClassOf obo:CHEBI_33285 , obo:CHEBI_37578 . obo:PR_000014023 a rdfs:Class ; rdfs:label "receptor-interacting serine/threonine-protein kinase 2" ; rdfs:comment "A protein that is a translation product of the human RIPK2 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:PR_P22607 a rdfs:Class ; rdfs:label "fibroblast growth factor receptor 3 (human)" ; rdfs:comment "A fibroblast growth factor receptor 3 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000001450 , obo:PR_000029067 . obo:VO_0000923 a rdfs:Class ; rdfs:label "RECOMBITEK Corona MLV" ; rdfs:subClassOf obo:VO_0000932 . obo:CHEBI_37334 a rdfs:Class ; rdfs:label "diagnostic imaging agent" ; rdfs:comment "A substance administered to enhance contrast in images of the inside of the body obtained using X-rays, gamma-rays, sound waves, radio waves (MRI), or radioactive particles in order to diagnose disease." ; rdfs:subClassOf obo:CHEBI_33295 . obo:CIDO_0001202 a rdfs:Class ; rdfs:label "Multiple Real-Time PCR Kit for Detection of 2019-nCoV. (Shanghai Fosun LONG March MEDICAL Science Co., Ltd.)" ; rdfs:comment "Poduct storage conditions and expiration date: The kit should be protected from light and sealed at -15℃～-25℃, and the validity period is 10 months." ; rdfs:subClassOf obo:CIDO_0000021 . obo:PR_P05231 a rdfs:Class ; rdfs:label "interleukin-6 (human)" ; rdfs:comment "An interleukin-6 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000001393 , obo:PR_000029067 . obo:RO_0002598 a rdf:Property ; rdfs:label "capable of positively regulating" ; rdfs:comment "Holds between c and p if and only if c is capable of some activity a, and a positively regulates p." ; rdfs:range ; rdfs:subPropertyOf obo:RO_0002596 . obo:PR_000003064 a rdfs:Class ; rdfs:label "tyrosine-protein kinase ZAP-70" ; rdfs:comment "A SYK/ZAP-70 family tyrosine-protein kinase that is a translation product of the human ZAP70 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000003063 . obo:CHEBI_27641 a rdfs:Class ; rdfs:label "cycloheximide" ; rdfs:comment "A dicarboximide that is 4-(2-hydroxyethyl)piperidine-2,6-dione in which one of the hydrogens attached to the carbon bearing the hydroxy group is replaced by a 3,5-dimethyl-2-oxocyclohexyl group. It is an antibiotic produced by the bacterium Streptomyces griseus." ; rdfs:subClassOf obo:CHEBI_35356 , obo:CHEBI_35681 , obo:CHEBI_3992 , obo:CHEBI_48589 , obo:CHEBI_49318 , obo:CHEBI_87114 . obo:CHEBI_35705 a rdfs:Class ; rdfs:label "immunosuppressive agent" ; rdfs:comment "An agent that suppresses immune function by one of several mechanisms of action. Classical cytotoxic immunosuppressants act by inhibiting DNA synthesis. Others may act through activation of T-cells or by inhibiting the activation of helper cells. In addition, an immunosuppressive agent is a role played by a compound which is exhibited by a capability to diminish the extent and/or voracity of an immune response." ; rdfs:subClassOf obo:CHEBI_50846 . a rdfs:Class ; rdfs:label "Aortic Valve Stenosis [Disease/Finding]" ; rdfs:subClassOf , . obo:PR_P0DTC1 a rdfs:Class . obo:CHEBI_76736 a rdfs:Class ; rdfs:label "EC 1.9.* (oxidoreductase acting on donor heme group) inhibitor" ; rdfs:comment "An oxidoreductase inhibitor which interferes with the action of an oxidoreductase acting on a heme group of donors (EC 1.9.*.*)." ; rdfs:subClassOf obo:CHEBI_76725 . obo:PR_Q15369 a rdfs:Class ; rdfs:label "elongin-C (human)" ; rdfs:comment "An elongin-C that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000016168 , obo:PR_000029067 . obo:CHEBI_133004 a rdfs:Class ; rdfs:label "bisbenzylisoquinoline alkaloid" ; rdfs:comment "A type of benzylisoquinoline alkaloid whose structures are built up of two benzylisoquinoline units linked by ether bridges. Various structural patterns resulting from additional bridging between the two units by direct carbon-carbon bridging or by methylenedioxy groups are common." ; rdfs:subClassOf obo:CHEBI_22750 . obo:NCBITaxon_1679920 a rdfs:Class ; rdfs:label "Coronavirus RCoV/RMU10_620/Apo_agr/GER/2010" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:GO_0031399 a rdfs:Class ; rdfs:label "regulation of protein modification process" ; rdfs:comment "Any process that modulates the frequency, rate or extent of the covalent alteration of one or more amino acid residues within a protein." ; rdfs:subClassOf obo:GO_0032268 . a rdfs:Class ; rdfs:label "Secernentea Infections [Disease/Finding]" ; rdfs:subClassOf . obo:CHEBI_63473 a rdfs:Class ; rdfs:label "aromatic amino-acid anion" ; rdfs:comment "An aromatic amino acid whose alpha-carboxylic acid group is ionized (non-protonated)." ; rdfs:subClassOf obo:CHEBI_37022 . a rdfs:Class ; rdfs:label "Lipids [Chemical/Ingredient]" ; rdfs:subClassOf . obo:PR_000029578 a rdfs:Class ; rdfs:label "protein O-glucosyltransferase 3" ; rdfs:comment "A protein that is a translation product of the human POGLUT3 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:CHEBI_46700 a rdfs:Class ; rdfs:label "benzoxazole" ; rdfs:comment "Compounds based on a fused 1,2- or 1,3-oxazole and benzene bicyclic ring skeleton." ; rdfs:subClassOf obo:CHEBI_27171 , obo:CHEBI_38101 , obo:CHEBI_38104 . obo:NCBITaxon_424360 a rdfs:Class ; rdfs:label "Bat coronavirus HKU4-2" ; rdfs:subClassOf obo:NCBITaxon_694007 . obo:CIDO_0001130 a rdfs:Class ; rdfs:label "SARS-CoV2 orf8 protein binding to human PLOD2"@en ; rdfs:comment "SARS-CoV2 orf8 protein binding to human PLOD2, as evidented by an affinity-purification mass spectrometry experiment" ; rdfs:subClassOf obo:CIDO_0000051 . obo:VO_0000494 a rdfs:Class ; rdfs:label "vaccine immunization" ; rdfs:comment "artificial active immunization is an active immunization that occurs when a person or animal is vaccinated with a specific vaccine." ; rdfs:subClassOf obo:VO_0000491 . obo:NCBITaxon_1146864 a rdfs:Class ; rdfs:label "Bat coronavirus M.nattereri/UK/Wyt/1023A" ; rdfs:subClassOf obo:NCBITaxon_366617 . obo:CHEBI_33838 a rdfs:Class ; rdfs:label "nucleoside" ; rdfs:comment "Nucleosides are ribosyl or deoxyribosyl derivatives of the pyrimidine or purine bases adenine, guanine, xanthine, thymine, cytosine, and uracil." ; rdfs:subClassOf obo:CHEBI_21731 , obo:CHEBI_26912 , obo:CHEBI_61120 . a rdfs:Class ; rdfs:label "Demyelinating Diseases [Disease/Finding]" ; rdfs:subClassOf . obo:CIDO_0020243 a rdfs:Class ; rdfs:label "Psoma COVID-19 RT Test" ; rdfs:seeAlso ; rdfs:subClassOf obo:CIDO_0000454 . obo:CIDO_0000703 a rdfs:Class ; rdfs:label "T95I in SARS-CoV-2 S protein" ; rdfs:comment "An AA mutation or AA variant that has mutated an amino acid at position 95 into a isoleucine in S protein." ; rdfs:subClassOf obo:CIDO_0000594 . obo:PR_000011203 a rdfs:Class ; rdfs:label "NHP2-like protein 1" ; rdfs:comment "A protein that is a translation product of the human SNU13 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:CIDO_0000676 a rdfs:Class ; rdfs:label "L18F in SARS-CoV-2 S protein" ; rdfs:comment "An AA mutation or AA variant that has mutated an amino acid at position 18 into a phenylalanine" ; rdfs:subClassOf obo:CIDO_0000594 . obo:CHEBI_33719 a rdfs:Class ; rdfs:label "alpha-amino-acid cation" ; rdfs:subClassOf obo:CHEBI_33703 . obo:OAE_0000401 a rdfs:Class ; rdfs:label "sweating AE" ; rdfs:comment "a skin adverse event that has an outcome of sweating" ; rdfs:subClassOf obo:OAE_0000543 . obo:PR_000002032 a rdfs:Class ; rdfs:label "angiopoietin-1 receptor" ; rdfs:comment "A receptor-type tyrosine-protein kinase Tie that is a translation product of the human TEK gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000001923 . obo:NCBITaxon_9685 a rdfs:Class ; rdfs:label "Felis catus" ; rdfs:subClassOf obo:NCBITaxon_9682 . obo:CIDO_0000279 a rdfs:Class ; rdfs:label "A222V in SARS-CoV-2 S protein" ; rdfs:comment "An AA variant that has mutated an amino acid at position 222 into valine in S protein." ; rdfs:subClassOf obo:CIDO_0000594 . a rdfs:Class ; rdfs:label "Ergotamines [Chemical/Ingredient]" ; rdfs:subClassOf , . obo:CHEBI_149551 a rdfs:Class ; rdfs:label "emetine dihydrochloride" ; rdfs:comment "The dihydrochloride salt of emetine." ; rdfs:subClassOf obo:CHEBI_36807 . a rdfs:Class ; rdfs:label "Vaginal Diseases [Disease/Finding]" ; rdfs:subClassOf . obo:CHEBI_22323 a rdfs:Class ; rdfs:label "alkyl group" ; rdfs:comment "A univalent group -CnH2n+1 derived from an alkane by removal of a hydrogen atom from any carbon atom." ; rdfs:subClassOf obo:CHEBI_33248 . obo:OGMS_0000104 a rdfs:Class ; rdfs:label "diagnostic process" ; rdfs:comment "A health care process that involves the interpretation of a clinical picture from a given patient (input) and the assertion to the effect that the patient has a disease, disorder, or syndrome of a certain type, or none of these (output)."@en ; rdfs:subClassOf obo:OBI_0000011 . obo:NCBITaxon_9973 a rdfs:Class ; rdfs:label "Manis" ; rdfs:subClassOf obo:NCBITaxon_9972 . obo:OBI_0002511 a rdfs:Class ; rdfs:label "vitreous humor specimen" ; rdfs:comment "A specimen that is derived from vireous humor." ; rdfs:subClassOf obo:OBI_0001479 . obo:CHEBI_37848 a rdfs:Class ; rdfs:label "plant hormone" ; rdfs:comment "A plant growth regulator that modulates the formation of stems, leaves and flowers, as well as the development and ripening of fruit. The term includes endogenous and non-endogenous compounds (e.g. active compounds produced by bacteria on the leaf surface) as well as semi-synthetic and fully synthetic compounds." ; rdfs:subClassOf obo:CHEBI_24621 , obo:CHEBI_26155 . obo:OPMI_0000535 a rdfs:Class ; rdfs:label "primary admission diagnosis status"@en ; rdfs:comment "The status of have the primary admission diagnosis" ; rdfs:subClassOf obo:OPMI_0000526 . obo:CHEBI_32558 a rdfs:Class ; rdfs:label "D-lysinium(2+)" ; rdfs:comment "The D-enantiomer of lysinium(2+)." ; rdfs:subClassOf obo:CHEBI_32565 . obo:CIDO_0000758 a rdfs:Class ; rdfs:label "SARS-CoV2 M protein binding to human GGCX" ; rdfs:comment "SARS-CoV2 M protein binding to human GGCX, as evidented by an affinity-purification mass spectrometry experiment" ; rdfs:subClassOf obo:CIDO_0000055 . obo:CHEBI_33256 a rdfs:Class ; rdfs:label "primary amide" ; rdfs:comment "A derivative of an oxoacid RkE(=O)l(OH)m (l =/= 0) in which an acidic hydroxy group has been replaced by an amino or substituted amino group." ; rdfs:subClassOf obo:CHEBI_32988 . a rdfs:Class ; rdfs:label "Quinuclidines [Chemical/Ingredient]" ; rdfs:subClassOf . obo:NCBITaxon_1788488 a rdfs:Class ; rdfs:label "Rhinolophus bat coronavirus BtCoV/3992-2" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:CIDO_0020062 a rdfs:Class ; rdfs:label "Bio-Rad SARS CoV-2-ddPCR Test" ; rdfs:seeAlso ; rdfs:subClassOf obo:CIDO_0000454 . obo:PR_P33981 a rdfs:Class ; rdfs:label "dual specificity protein kinase TTK (human)" ; rdfs:comment "A dual specificity protein kinase TTK that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000016787 , obo:PR_000029067 . obo:CIDO_0000401 a rdfs:Class ; rdfs:label "SARS-CoV-2 AY.2 virus"@en ; rdfs:subClassOf obo:CIDO_0000406 . obo:NCBITaxon_264382 a rdfs:Class ; rdfs:label "SARS coronavirus TW-GD5" ; rdfs:subClassOf obo:NCBITaxon_264370 . obo:CIDO_0000257 a rdfs:Class ; rdfs:label "papain-like protease inhibitor role"@en ; rdfs:subClassOf obo:CHEBI_35222 . a rdfs:Class ; rdfs:label "NICLOSAMIDE" ; rdfs:subClassOf . obo:NCBITaxon_2020423 a rdfs:Class ; rdfs:label "Hypsugo bat coronavirus HKU25" ; rdfs:subClassOf obo:NCBITaxon_2664183 . obo:DOID_11257 a rdfs:Class ; rdfs:label "social phobia" ; rdfs:comment "A phobic disorder that involves social anxiety occurring only in specific public or social situations, interactions with others or being evaluated or scrutinized by other people." ; rdfs:subClassOf obo:DOID_591 . obo:CHEBI_60599 a rdfs:Class ; rdfs:label "mu-opioid agent" ; rdfs:comment "Any agent that acts on a mu-opioid receptor." ; rdfs:subClassOf obo:CHEBI_60598 . obo:PR_Q9UEW8 a rdfs:Class ; rdfs:label "STE20/SPS1-related proline-alanine-rich protein kinase (human)" ; rdfs:comment "A STE20/SPS1-related proline-alanine-rich protein kinase that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000015756 , obo:PR_000029067 . obo:CIDO_0000076 a rdfs:Class ; rdfs:label "chemical role against coronaviral entry"@en ; rdfs:subClassOf obo:CIDO_0000067 . obo:PR_000011513 a rdfs:Class ; rdfs:label "nuclear pore membrane glycoprotein 210" ; rdfs:comment "A protein that is a translation product of the human NUP210 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:NCBITaxon_871682 a rdfs:Class ; rdfs:label "Feline coronavirus UU31" ; rdfs:subClassOf obo:NCBITaxon_12663 . obo:CHEBI_24469 a rdfs:Class ; rdfs:label "haloalkane" ; rdfs:comment "A halohydrocarbon that is an alkane in which at least one hydrogen atom has been replaced by with a halogen atom." ; rdfs:subClassOf obo:CHEBI_24472 . obo:NCBITaxon_267383 a rdfs:Class ; rdfs:label "SARS coronavirus Sin842" ; rdfs:subClassOf obo:NCBITaxon_694009 . obo:CIDO_0000549 a rdfs:Class ; rdfs:label "SVATFYIEHYVNRLV" ; rdfs:comment "A coronavirus epitope that is part of some S protein from HCoV HKU1 composed of the following amino acids SVATFYIEHYVNRLV" ; rdfs:subClassOf obo:CIDO_0000450 . obo:CIDO_0020239 a rdfs:Class ; rdfs:label "Poplar SARS-CoV-2 TMA Pooling assay" ; rdfs:seeAlso ; rdfs:subClassOf obo:CIDO_0000454 . obo:PR_P33527 a rdfs:Class ; rdfs:label "multidrug resistance-associated protein 1 (human)" ; rdfs:comment "A multidrug resistance-associated protein 1 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000003554 , obo:PR_000029067 . obo:PATO_0001332 a rdfs:Class ; rdfs:label "amorphous" ; rdfs:comment "A morphology quality inhering in a bearer by virtue of the bearer's lack of distinct morphology." ; rdfs:subClassOf obo:PATO_0000051 . obo:PR_000044678 a rdfs:Class ; rdfs:label "chloride channel protein" ; rdfs:comment "An ion channel protein that has chloride channel activity. A chloride channel enables the facilitated diffusion of a chloride (by an energy-independent process) involving passage through a transmembrane aqueous pore or channel without evidence for a carrier-mediated mechanism." ; rdfs:subClassOf obo:PR_000049983 . a rdfs:Class ; rdfs:label "Generalized Systemic Effects [PE]" ; rdfs:subClassOf . obo:PR_Q9BRN9 a rdfs:Class ; rdfs:label "TM2 domain-containing protein 3 (human)" ; rdfs:comment "A TM2 domain-containing protein 3 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000029067 , obo:PR_000029807 . obo:NCBITaxon_2749449 a rdfs:Class ; rdfs:label "Coronavirus cyb-BetaCoV/2019" ; rdfs:subClassOf obo:NCBITaxon_1986197 . obo:NCBITaxon_11149 a rdfs:Class ; rdfs:label "Transmissible gastroenteritis virus" ; rdfs:subClassOf obo:NCBITaxon_693997 . a rdfs:Class ; rdfs:label "Cellular Degradation/Digestion Alteration [PE]" ; rdfs:subClassOf . obo:NCBITaxon_235411 a rdfs:Class ; rdfs:label "SARS coronavirus Sin2748" ; rdfs:subClassOf obo:NCBITaxon_694009 . obo:CHEBI_78433 a rdfs:Class ; rdfs:label "refrigerant" ; rdfs:comment "A substance used in a thermodynamic heat pump cycle or refrigeration cycle that undergoes a phase change from a gas to a liquid and back. Refrigerants are used in air-conditioning systems and freezers or refrigerators and are assigned a \"R\" number (by ASHRAE - formerly the American Society of Heating, Refrigerating and Air Conditioning Engineers), which is determined systematically according to their molecular structure." ; rdfs:subClassOf obo:CHEBI_33232 . obo:NCBITaxon_1679905 a rdfs:Class ; rdfs:label "Coronavirus RCoV/KS10_2743/Mic_arv/GER/2010" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:CHEBI_51737 a rdfs:Class ; rdfs:label "alpha,beta-unsaturated carboxylic ester" ; rdfs:comment "A carboxylic ester of general formula R(1)R(2)C=CR(3)-C(=O)OR(4) (R(4) =/= H) or R(1)C#C-C(=O)OR(2) (R(2) =/= H) in which the ester C=O function is conjugated to an unsaturated C-C bond at the alpha,beta position." ; rdfs:subClassOf obo:CHEBI_33308 . obo:PR_Q9H1R3 a rdfs:Class ; rdfs:label "myosin light chain kinase 2, skeletal/cardiac muscle (human)" ; rdfs:comment "A myosin light chain kinase 2, skeletal/cardiac muscle that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000010846 , obo:PR_000029067 . obo:DRON_00000001 a rdfs:Class ; rdfs:label "clinical drug role"@en ; rdfs:comment "the role of a material entity to prevent, diagnose, treat, or study disease and/or its effects"@en ; rdfs:subClassOf obo:BFO_0000023 . obo:VO_0000128 a rdfs:Class ; rdfs:label "aluminum phosphate vaccine adjuvant" ; rdfs:comment "an aluminum vaccine adjuvant that is aluminum phosphate." ; rdfs:subClassOf obo:VO_0000884 . obo:UBERON_0000483 a rdfs:Class ; rdfs:label "epithelium" ; rdfs:comment "Portion of tissue, that consists of one or more layers of epithelial cells connected to each other by cell junctions and which is underlain by a basal lamina. Examples: simple squamous epithelium, glandular cuboidal epithelium, transitional epithelium, myoepithelium[CARO]." ; rdfs:subClassOf obo:UBERON_0000479 . obo:CHEBI_7735 a rdfs:Class ; rdfs:label "olanzapine" ; rdfs:comment "A benzodiazepine that is 10H-thieno[2,3-b][1,5]benzodiazepine substituted by a methyl group at position 2 and a 4-methylpiperazin-1-yl group at position 4." ; rdfs:subClassOf obo:CHEBI_22720 , obo:CHEBI_46848 , obo:CHEBI_46920 . obo:PR_000004071 a rdfs:Class ; rdfs:label "annexin A1" ; rdfs:comment "An annexin A that is a translation product of the human ANXA1 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000050012 . obo:NCBITaxon_1261612 a rdfs:Class ; rdfs:label "Mops bat coronavirus/South Africa/1364/2011" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:VO_0000309 a rdfs:Class ; rdfs:label "vaccine-induced antibody mediated immune response" ; rdfs:subClassOf obo:VO_0000012 . obo:CIDO_0020164 a rdfs:Class ; rdfs:label "HDPCR SARS-CoV-2 Assay" ; rdfs:seeAlso ; rdfs:subClassOf obo:CIDO_0000454 . obo:NCBITaxon_413073 a rdfs:Class ; rdfs:label "Infectious bronchitis virus PRT/L-898/2004" ; rdfs:subClassOf obo:NCBITaxon_11120 . obo:OBIB_0000714 a rdfs:Class ; rdfs:label "date of specimen collection"@en ; rdfs:comment "A data item that indicates the time when the collection of a specimen occurred."@en ; rdfs:subClassOf obo:IAO_0000027 . obo:CIDO_0000624 a rdfs:Class ; rdfs:label "I82T in SARS-CoV-2 M protein" ; rdfs:comment "An AA mutation or AA variant that has mutated an amino acid at position 182 into a threonine in M protein." ; rdfs:subClassOf obo:CIDO_0000619 . obo:NCBITaxon_1335626 a rdfs:Class ; rdfs:label "Middle East respiratory syndrome-related coronavirus" ; rdfs:subClassOf obo:NCBITaxon_2509494 , obo:NCBITaxon_694002 . obo:CIDO_0000413 a rdfs:Class ; rdfs:label "susceptibility to up-regulation in COVID-19 patient"@en ; rdfs:comment "A disposition that a material entity such as a gene or protein is susceptible to be up-regulated in COVID-19 patient" ; rdfs:subClassOf obo:CIDO_0000412 . obo:HP_0000821 a rdfs:Class ; rdfs:label "Hypothyroidism" ; rdfs:comment "Deficiency of thyroid hormone." ; rdfs:subClassOf obo:HP_0000820 . a rdfs:Class ; rdfs:label "Breast Function Alteration [PE]" ; rdfs:subClassOf . a rdfs:Class ; rdfs:label "Clostridium Infections [Disease/Finding]" ; rdfs:subClassOf . obo:CHEBI_5855 a rdfs:Class ; rdfs:label "ibuprofen" ; rdfs:comment "A monocarboxylic acid that is propionic acid in which one of the hydrogens at position 2 is substituted by a 4-(2-methylpropyl)phenyl group." ; rdfs:subClassOf obo:CHEBI_25384 . obo:CIDO_0000126 a rdf:Property ; rdfs:label "chemical activates protein"@en ; rdfs:comment "An object property that represents a relation between a chemical entity and a protein where the chemical entity can target the protein as an enzyme activator. Note that the chemical entity is usually an active compound of a corresponding drug. An enzyme inducer is a type of drug or chemcial that increases the metabolic activity of an enzyme either by binding to the enzyme and activating it, or by increasing the expression of the gene coding for the enzyme." ; rdfs:range ; rdfs:subPropertyOf obo:CIDO_0000118 . obo:CHEBI_101381 a rdfs:Class ; rdfs:label "aloxistatin" ; rdfs:comment "An L-leucine derivative that is the amide obtained by formal condensation of the carboxy group of (2S,3S)-3-(ethoxycarbonyl)oxirane-2-carboxylic acid with the amino group of N-(3-methylbutyl)-L-leucinamide." ; rdfs:subClassOf obo:CHEBI_23990 , obo:CHEBI_25018 , obo:CHEBI_29347 , obo:CHEBI_32955 . obo:CIDO_0000343 a rdfs:Class ; rdfs:label "LNEVAKNLNESLIDL"@en ; rdfs:subClassOf obo:CIDO_0000314 . obo:CHEBI_32504 a rdfs:Class ; rdfs:label "phenylalaninate" ; rdfs:comment "An aromatic amino-acid anion that is the conjugate base of phenylalanine, arising from deprotonation of the carboxy group." ; rdfs:subClassOf obo:CHEBI_33558 , obo:CHEBI_63473 . obo:PR_000029527 a rdfs:Class ; rdfs:label "procollagen galactosyltransferase 1" ; rdfs:comment "A protein that is a translation product of the human COLGALT1 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:CIDO_0020124 a rdfs:Class ; rdfs:label "DxTerity SARS-CoV-2 RT-PCR Test" ; rdfs:seeAlso ; rdfs:subClassOf obo:CIDO_0000454 . obo:CHEBI_33497 a rdfs:Class ; rdfs:label "transition element molecular entity" ; rdfs:comment "A molecular entity containing one or more atoms of a transition element." ; rdfs:subClassOf obo:CHEBI_23367 . a rdfs:Class ; rdfs:label "Furans [Chemical/Ingredient]" ; rdfs:subClassOf . obo:PR_000011527 a rdfs:Class ; rdfs:label "nucleoporin p58/p45" ; rdfs:comment "A protein that is a translation product of the human NUP58 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:OBI_2000007 a rdfs:Class ; rdfs:label "nasopharynx specimen" ; rdfs:comment "A specimen that is derived from some nasopharynx " ; rdfs:subClassOf obo:OBI_0001479 . obo:CHEBI_37935 a rdfs:Class ; rdfs:label "3H-phenothiazine" ; rdfs:subClassOf obo:CHEBI_37932 . obo:NCBITaxon_1146853 a rdfs:Class ; rdfs:label "Bat coronavirus M.nattereri/UK/Sav/1089B" ; rdfs:subClassOf obo:NCBITaxon_366617 . a rdfs:Class ; rdfs:label "Ribonucleosides [Chemical/Ingredient]" ; rdfs:subClassOf . obo:PR_P06870 a rdfs:Class ; rdfs:label "kallikrein-1 (human)" ; rdfs:comment "A kallikrein-1 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000009406 , obo:PR_000029067 . obo:NCBITaxon_253433 a rdfs:Class ; rdfs:label "SARS coronavirus PUMC01" ; rdfs:subClassOf obo:NCBITaxon_694009 . obo:CHEBI_17514 a rdfs:Class ; rdfs:label "cyanide" ; rdfs:comment "A pseudohalide anion that is the conjugate base of hydrogen cyanide." ; rdfs:subClassOf obo:CHEBI_36828 . obo:HP_0001688 a rdfs:Class ; rdfs:label "Sinus bradycardia" ; rdfs:comment "Bradycardia related to a mean resting sinus rate of less than 50 beats per minute." ; rdfs:subClassOf obo:HP_0001662 , obo:HP_0011702 . a rdfs:Class ; rdfs:label "TOREMIFENE" ; rdfs:subClassOf . a rdfs:Class ; rdfs:label "chloroquine diphosphate [Chemical/Ingredient]" ; rdfs:subClassOf . obo:CIDO_0020012 a rdfs:Class ; rdfs:label "AdviseDx SARS-CoV-2 IgM" ; rdfs:seeAlso ; rdfs:subClassOf obo:CIDO_0000454 . obo:PR_P14616 a rdfs:Class ; rdfs:label "insulin receptor-related protein (human)" ; rdfs:comment "An insulin receptor-related protein that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000009065 , obo:PR_000029067 . obo:PR_000016341 a rdfs:Class ; rdfs:label "mitochondrial import inner membrane translocase subunit Tim10" ; rdfs:comment "A protein that is a translation product of the human TIMM10 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:CIDO_0000718 a rdfs:Class ; rdfs:label "L3930F in SARS-CoV-2 pp1a protein"@en ; rdfs:comment "An AA mutation or AA variant that has mutated an amino acid at position 3930 into a phenylalanine in pp1a." ; rdfs:subClassOf obo:CIDO_0001079 . obo:PR_A3KN83 a rdfs:Class ; rdfs:label "protein strawberry notch homolog 1 (human)" ; rdfs:comment "A protein strawberry notch homolog 1 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000014476 , obo:PR_000029067 . obo:CHEBI_24302 a rdfs:Class ; rdfs:label "glucosiduronic acid" ; rdfs:comment "Any substance produced by linking glucuronic acid to another substance via a glycosidic bond." ; rdfs:subClassOf obo:CHEBI_35314 , obo:CHEBI_63436 . obo:NCBITaxon_903629 a rdfs:Class ; rdfs:label "Kenya bat coronavirus BtKY91" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:VO_0005129 a rdfs:Class ; rdfs:label "UV-Inactivated SARS vaccine" ; rdfs:comment "A SARS inactivated vaccine made from SARS-CoV inactivated by ultraviolet radiation" ; rdfs:subClassOf obo:VO_0012183 . obo:CIDO_0000516 a rdfs:Class ; rdfs:label "RVAGRSAIEDILFSK" ; rdfs:comment "A coronavirus epitope that is part of some S protein from HCoV 229E composed of the following amino acids RVAGRSAIEDILFSK" ; rdfs:subClassOf obo:CIDO_0000451 . obo:NCBITaxon_903592 a rdfs:Class ; rdfs:label "Kenya bat coronavirus BtKY54" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:CHEBI_24533 a rdfs:Class ; rdfs:label "heterodetic cyclic peptide" ; rdfs:comment "A heterodetic cyclic peptide is a peptide consisting only of amino-acid residues, but in which the linkages forming the ring are not solely peptide bonds; one or more is an isopeptide, disulfide, ester, or other bond." ; rdfs:subClassOf obo:CHEBI_23449 . obo:PR_O95259 a rdfs:Class ; rdfs:label "potassium voltage-gated channel subfamily H member 1 (human)" ; rdfs:comment "A voltage-gated potassium channel KCNH1 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000000790 , obo:PR_000029067 . obo:VO_0000288 a rdfs:Class ; rdfs:label "vaccine-induced host response" ; rdfs:comment "a processual entity that specifies host response to a vaccine." ; rdfs:subClassOf obo:BFO_0000015 . obo:NCBITaxon_1476951 a rdfs:Class ; rdfs:label "Bat coronavirus IFB2012-8F" ; rdfs:subClassOf obo:NCBITaxon_696098 . obo:CIDO_0000323 a rdfs:Class ; rdfs:label "IVRFPNITNLCPFGE"@en ; rdfs:subClassOf obo:CIDO_0000314 . obo:PR_Q9UBU6 a rdfs:Class ; rdfs:label "protein FAM8A1 (human)" ; rdfs:comment "A protein FAM8A1 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000029067 , obo:PR_000029489 . obo:NCBITaxon_742314 a rdfs:Class ; rdfs:label "Ferret systemic coronavirus" ; rdfs:subClassOf obo:NCBITaxon_1264898 . obo:PR_000036009 a rdfs:Class ; rdfs:label "angiotensin II" ; rdfs:comment "An angiotensinogen proteolytic cleavage product that is formed via the action of angiotensin converting enzyme on angiotensin I." ; rdfs:subClassOf obo:PR_000018932 . obo:CIDO_0000360 a rdf:Property ; rdfs:label "binding to receptor"@en ; rdfs:comment "An object property that represents a relation between a molecule and a receptor of the molecule where the molecule binds physically to the receptor." ; rdfs:range . obo:CIDO_0000387 a rdfs:Class ; rdfs:label "Polyman26"@en ; rdfs:comment "A multivalent glycomimetic mannoside that can act as a glycomimetic antagonist by interaction with DC-SIGN (i.e., CD209 antigen). The DC/L-SIGN recognition of spike glycoprotein promotes SARS-CoV-2 trans-infection, which can be inhibited by PM26, a glycomimetic antagonist." ; rdfs:subClassOf obo:CHEBI_23367 . obo:CHEBI_145999 a rdfs:Class ; rdfs:label "cinanserin" ; rdfs:comment "An aryl sulfide that is (2E)-3-phenyl-N-(2-sulfanylphenyl)prop-2-enamide in which the hydrogen of the thiol group is substituted by a 3-(dimethylamino)propyl group. It is a 5-hydroxytryptamine receptor antagonist and an inhibitor of SARS-CoV replication." ; rdfs:subClassOf obo:CHEBI_140325 , obo:CHEBI_23247 , obo:CHEBI_35683 , obo:CHEBI_50996 . obo:NCBITaxon_702703 a rdfs:Class ; rdfs:label "Bovine coronavirus Bubalus/155/ITA/2008" ; rdfs:subClassOf obo:NCBITaxon_11128 . obo:CHEBI_29687 a rdfs:Class ; rdfs:label "teicoplanin" ; rdfs:comment "A complex mixture of related natural products isolated from the fermentation broth of a strain of Actinoplanes teichomyceticus comprising five major components (teicoplanin A2-1 through A2-5), a hydrolysis component (teicoplanin A3-1), and four minor components (teicoplanin RS-1 through RS-4). An antibiotic with a similar spectrum of activity to vancomycin, it is used to treat serious Gram-positive bacterial infections, including methicillin-resistant Staphylococcus aureus and Enterococcus faecalis." ; rdfs:subClassOf obo:CHEBI_60004 . obo:NCBITaxon_1034321 a rdfs:Class ; rdfs:label "Rm-Bat-CoV 453/2007/EF" ; rdfs:subClassOf obo:NCBITaxon_366617 . obo:NCBITaxon_1679892 a rdfs:Class ; rdfs:label "Coronavirus RCoV/D_RMU10_1974/Myo_gla/GER/2010" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:PR_P09429 a rdfs:Class ; rdfs:label "high mobility group protein B1 (human)" ; rdfs:comment "A high mobility group protein B1 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000008630 , obo:PR_000029067 . obo:PR_000009021 a rdfs:Class ; rdfs:label "inosine-5'-monophosphate dehydrogenase 1" ; rdfs:comment "A protein that is a translation product of the human IMPDH1 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:CIDO_0000719 a rdfs:Class ; rdfs:label "V1176F in SARS-CoV-2 S protein"@en ; rdfs:comment "An AA mutation or AA variant that has mutated an amino acid at position 1176 into a phenylalanine in S protein." ; rdfs:subClassOf obo:CIDO_0001164 . a rdfs:Class ; rdfs:label "Peptides, Cyclic [Chemical/Ingredient]" ; rdfs:subClassOf , . obo:VO_0000886 a rdfs:Class ; rdfs:label "oral route" ; rdfs:subClassOf obo:VO_0000574 . obo:PR_000014235 a rdfs:Class ; rdfs:label "60S ribosomal protein L8" ; rdfs:comment "A protein that is a translation product of the human RPL8 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:CIDO_0020221 a rdfs:Class ; rdfs:label "OmniPATH COVID-19 Total Antibody ELISA Test" ; rdfs:seeAlso ; rdfs:subClassOf obo:CIDO_0000454 . obo:HP_0100845 a rdfs:Class ; rdfs:label "Anaphylactic shock" ; rdfs:comment "An acute hypersensitivity reaction due to exposure to a previously encountered antigen." ; rdfs:subClassOf obo:HP_0100326 . obo:CIDO_0000602 a rdfs:Class ; rdfs:label "AA variant in SARS-CoV-2 ORF1ab polyprotein product"@en ; rdfs:comment "An AA variant that is found in comparison to the ORF1ab polyprotein product. The AA variants in this polyprotein are equivalent to AA variants found in the non-structural protein." ; rdfs:subClassOf obo:CIDO_0000237 . obo:DOID_0080832 a rdfs:Class ; rdfs:label "mild cognitive impairment"@en ; rdfs:comment "A cognitive disorder that is characterized by objective impairment in cognition with minimal impairment of their capacity to undertake the instrumental activities of daily living." ; rdfs:subClassOf obo:DOID_1561 . obo:PR_P62829 a rdfs:Class ; rdfs:label "60S ribosomal protein L23 (human)" ; rdfs:comment "A 60S ribosomal protein L23 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000014203 , obo:PR_000029067 . obo:VO_0005415 a rdfs:Class ; rdfs:label "mRNA-1273.214"@en ; rdfs:comment "A SARS-CoV-2 bivalent mRNA vaccine by Moderna that contains the mRNA-1273 COVID-19 vaccine and the mRNA-1273.214 Omicron booster" ; rdfs:subClassOf obo:VO_0005198 . obo:CHEBI_50331 a rdfs:Class ; rdfs:label "3-amino-3-oxopropyl group" ; rdfs:subClassOf obo:CHEBI_50325 . obo:NCBITaxon_745734 a rdfs:Class ; rdfs:label "Coronavirus M.das/VM73/2007/NLD" ; rdfs:subClassOf obo:NCBITaxon_696098 . obo:PR_000004801 a rdfs:Class ; rdfs:label "B-Raf proto-oncogene serine/threonine-protein kinase" ; rdfs:comment "A protein that is a translation product of the human BRAF gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:NCBITaxon_1532168 a rdfs:Class ; rdfs:label "Alphacoronavirus BtCoV/GrNC5/Neo_cap/RSA/2012" ; rdfs:subClassOf obo:NCBITaxon_366617 . obo:NCBITaxon_756651 a rdfs:Class ; rdfs:label "Bovine coronavirus cow/WDBR-54/BRA/2003" ; rdfs:subClassOf obo:NCBITaxon_11128 . obo:VO_0005396 a rdfs:Class ; rdfs:label "EgyVax"@en ; rdfs:comment "A SARS-CoV-2 inactivated vaccine developed by Eva Pharma." ; rdfs:subClassOf obo:VO_0005201 . obo:PR_Q13546 a rdfs:Class ; rdfs:label "receptor-interacting serine/threonine-protein kinase 1 (human)" ; rdfs:comment "A receptor-interacting serine/threonine-protein kinase 1 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000014022 , obo:PR_000029067 . a rdfs:Class ; rdfs:label "Toremifene Citrate [Chemical/Ingredient]" ; rdfs:subClassOf . obo:NCBITaxon_2691585 a rdfs:Class ; rdfs:label "Rousettus aegyptiacus bat coronavirus 229E-related" ; rdfs:subClassOf obo:NCBITaxon_2691584 . obo:CHEBI_76971 a rdfs:Class ; rdfs:label "Escherichia coli metabolite" ; rdfs:comment "Any bacterial metabolite produced during a metabolic reaction in Escherichia coli." ; rdfs:subClassOf obo:CHEBI_76969 . obo:NCBITaxon_1788466 a rdfs:Class ; rdfs:label "Miniopterus bat coronavirus BtCoV/3759-2" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:NCBITaxon_267398 a rdfs:Class ; rdfs:label "SARS coronavirus Sin850" ; rdfs:subClassOf obo:NCBITaxon_694009 . a rdfs:Class ; rdfs:label "Decreased T Lymphocyte Production [PE]" ; rdfs:subClassOf . obo:CIDO_0020030 a rdfs:Class ; rdfs:label "Aries SARS-CoV-2 Assay" ; rdfs:seeAlso ; rdfs:subClassOf obo:CIDO_0000454 . obo:VO_0005344 a rdfs:Class ; rdfs:label "COVIDITY"@en ; rdfs:comment "A SARS-CoV-2 DNA vaccine developed by Scancell Ltd." ; rdfs:subClassOf obo:VO_0005203 . obo:OPMI_0000510 a rdfs:Class ; rdfs:label "procedure end date"@en ; rdfs:comment "The date when a procedure ends" ; rdfs:subClassOf obo:OPMI_0000507 . obo:PR_000007128 a rdfs:Class ; rdfs:label "ephrin type-A receptor 8" ; rdfs:comment "An ephrin receptor that is a translation product of the human EPHA8 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000025845 . obo:NCBITaxon_1788417 a rdfs:Class ; rdfs:label "Bat coronavirus RaBtCoV/4307-2" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:PR_Q86V86 a rdfs:Class ; rdfs:label "serine/threonine-protein kinase pim-3 (human)" ; rdfs:comment "A serine/threonine-protein kinase Pim-3 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000012734 , obo:PR_000029067 . obo:CIDO_0000095 a rdfs:Class ; rdfs:label "host response to SARS-CoV infection"@en ; rdfs:comment "A coronavirus-host interaction by which the host responds to SARS-CoV viral infection" ; rdfs:subClassOf obo:CIDO_0000087 . obo:NCBITaxon_497950 a rdfs:Class ; rdfs:label "Bat coronavirus M.dau/Germany/D8.38/2007" ; rdfs:subClassOf obo:NCBITaxon_366617 . obo:PR_000013722 a rdfs:Class ; rdfs:label "Rap1 GTPase-GDP dissociation stimulator 1" ; rdfs:comment "A protein that is a translation product of the human RAP1GDS1 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:NCBITaxon_300187 a rdfs:Class ; rdfs:label "Goose coronavirus" ; rdfs:subClassOf obo:NCBITaxon_694014 . obo:IAO_0000007 a rdfs:Class ; rdfs:label "action specification"@en ; rdfs:comment "a directive information entity that describes an action the bearer will take"@en ; rdfs:subClassOf obo:IAO_0000033 . obo:HP_0001677 a rdfs:Class ; rdfs:label "Coronary artery atherosclerosis" ; rdfs:comment "Reduction of the diameter of the coronary arteries as the result of an accumulation of atheromatous plaques within the walls of the coronary arteries, which increases the risk of myocardial ischemia." ; rdfs:subClassOf obo:HP_0025015 . obo:CIDO_0000332 a rdfs:Class ; rdfs:label "KPSKRSFIEDLLFNK"@en ; rdfs:subClassOf obo:CIDO_0000314 . a rdfs:Class ; rdfs:label "Decreased Polymorphonuclear Leukocyte Migration [PE]" ; rdfs:subClassOf . obo:NCBITaxon_931908 a rdfs:Class ; rdfs:label "Alphacoronavirus Eptesicus fuscus/Appalachian Ridge/P1-293985/IT/USA/2009" ; rdfs:subClassOf obo:NCBITaxon_366617 . obo:NCBITaxon_2492657 a rdfs:Class ; rdfs:label "Alphacoronavirus Bat-CoV/P.kuhlii/Italy/206679-3/2010" ; rdfs:subClassOf obo:NCBITaxon_2727852 . a rdfs:Class ; rdfs:label "Retinal Degeneration [Disease/Finding]" ; rdfs:subClassOf . obo:GO_0060548 a rdfs:Class ; rdfs:label "negative regulation of cell death" ; rdfs:comment "Any process that decreases the rate or frequency of cell death. Cell death is the specific activation or halting of processes within a cell so that its vital functions markedly cease, rather than simply deteriorating gradually over time, which culminates in cell death." ; rdfs:subClassOf obo:GO_0010941 , obo:GO_0048523 . obo:NCBITaxon_1076427 a rdfs:Class ; rdfs:label "Betacoronavirus H.sav/J/Spain/2007" ; rdfs:subClassOf obo:NCBITaxon_696098 . obo:OBI_2000015 a rdfs:Class ; rdfs:label "capillary blood specimen" ; rdfs:comment "A specimen that is derived from some capillary blood" ; rdfs:subClassOf obo:OBI_2000009 . obo:DRON_00013349 a rdfs:Class ; rdfs:label "penciclovir" ; rdfs:subClassOf obo:OBI_0000047 . obo:CIDO_0000729 a rdfs:Class ; rdfs:label "Q1071H in SARS-CoV-2 S protein"@en ; rdfs:comment "An AA mutation or AA variant that has mutated an amino acid at position 1071 into a histidine in S protein." ; rdfs:subClassOf obo:CIDO_0000595 . obo:VO_0000457 a rdfs:Class ; rdfs:label "protective antigen role" ; rdfs:comment "Protective antigen is an antigen that stimulates protective immunity when used in vivo." ; rdfs:subClassOf obo:OBI_0000237 . obo:PR_000017548 a rdfs:Class ; rdfs:label "mitogen-activated protein kinase kinase kinase 19" ; rdfs:comment "A protein that is a translation product of the human MAP3K19 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:HP_0041051 a rdfs:Class ; rdfs:label "Ageusia" ; rdfs:comment "A rare condition that is characterized by a complete loss of taste function of the tongue." ; rdfs:subClassOf obo:HP_0000223 . obo:NCBITaxon_231517 a rdfs:Class ; rdfs:label "SARS coronavirus GZ43" ; rdfs:subClassOf obo:NCBITaxon_694009 . obo:PR_000001102 a rdfs:Class ; rdfs:label "5-hydroxytryptamine receptor 6" ; rdfs:comment "A 5-hydroxytryptamine receptor that is a translation product of the human HTR6 gene or a 1:1 ortholog thereof. The preferred ligand is 5-hydroxytryptamine (serotonin)." ; rdfs:subClassOf obo:PR_000044625 . obo:CHEBI_62434 a rdfs:Class ; rdfs:label "EC 2.7.10.1 (receptor protein-tyrosine kinase) inhibitor" ; rdfs:comment "An EC 2.7.10.* (protein-tyrosine kinase) inhibitor that interferes with the action of receptor protein-tyrosine kinase (EC 2.7.10.1)." ; rdfs:subClassOf obo:CHEBI_38637 , obo:CHEBI_76817 . obo:TRANS_0000002 a rdfs:Class ; rdfs:label "indirect" ; rdfs:comment "Indirect transmission is a transmission process during which the pathogen is indirectly transferred from a reservoir, source or host to another host by intermediary vehicles, vectors or as airborne dust particles." ; rdfs:subClassOf obo:TRANS_0000000 . obo:CHEBI_33266 a rdfs:Class ; rdfs:label "diatomic nitrogen" ; rdfs:subClassOf obo:CHEBI_33267 . obo:HP_0031273 a rdfs:Class ; rdfs:label "Shock" ; rdfs:comment "The state in which profound and widespread reduction of effective tissue perfusion leads first to reversible, and then if prolonged, to irreversible cellular injury." ; rdfs:subClassOf obo:HP_0011025 . obo:NCBITaxon_237640 a rdfs:Class ; rdfs:label "SARS coronavirus Taiwan TC2" ; rdfs:subClassOf obo:NCBITaxon_694009 . obo:GO_0001991 a rdfs:Class ; rdfs:label "regulation of systemic arterial blood pressure by circulatory renin-angiotensin" ; rdfs:comment "The process in which angiotensinogen metabolites in the bloodstream modulate the force with which blood passes through the circulatory system. The process begins when renin is released and cleaves angiotensinogen." ; rdfs:subClassOf obo:GO_0003081 . obo:NCBITaxon_535601 a rdfs:Class ; rdfs:label "Bovine coronavirus UP1/PRT/2005" ; rdfs:subClassOf obo:NCBITaxon_11128 . obo:CIDO_0000242 a rdfs:Class ; rdfs:label "G251V in SARS-CoV2 NS3 protein" ; rdfs:comment "an aa-changing SNP variant that occurs at G26144T at ORF3a protein of SARS-CoV-2 virus. It is a signature variation in SARS-CoV clade V." ; rdfs:subClassOf obo:CIDO_0000616 . obo:DRON_00021963 a rdfs:Class ; rdfs:label "Fluphenazine Oral Tablet" ; rdfs:subClassOf obo:DRON_00000022 . obo:GO_0009057 a rdfs:Class ; rdfs:label "macromolecule catabolic process" ; rdfs:comment "The chemical reactions and pathways resulting in the breakdown of a macromolecule, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass." ; rdfs:subClassOf obo:GO_0043170 , obo:GO_1901575 . a rdfs:Class ; rdfs:label "Proteins [Chemical/Ingredient]" ; rdfs:subClassOf . a rdfs:Class ; rdfs:label "GEMCITABINE" ; rdfs:subClassOf . obo:NCBITaxon_389246 a rdfs:Class ; rdfs:label "Bat coronavirus (BtCoV/A1196/2005)" ; rdfs:subClassOf obo:NCBITaxon_389126 . obo:PATO_0000051 a rdfs:Class ; rdfs:label "morphology" ; rdfs:comment "A quality of a single physical entity inhering in the bearer by virtue of the bearer's size or shape or structure." ; rdfs:subClassOf obo:PATO_0001241 . obo:CHEBI_51069 a rdfs:Class ; rdfs:label "organic halide salt" ; rdfs:subClassOf obo:CHEBI_24868 . obo:PR_000008295 a rdfs:Class ; rdfs:label "glutathione S-transferase A2" ; rdfs:comment "A glutathione S-transferase alpha that is a translation product of the human GSTA2 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000029946 . obo:NCBITaxon_1643902 a rdfs:Class ; rdfs:label "Bat coronavirus ANK081F" ; rdfs:subClassOf obo:NCBITaxon_696098 . obo:CHEBI_75768 a rdfs:Class ; rdfs:label "mammalian metabolite" ; rdfs:comment "Any animal metabolite produced during a metabolic reaction in mammals." ; rdfs:subClassOf obo:CHEBI_75767 . obo:CHEBI_9451 a rdfs:Class ; rdfs:label "terconazole" ; rdfs:comment "A racemate consisting of equimolar amounts of (2R,4S)- and (2S,4R)-terconazole. It has broad-spectrum antifungal activitiy and is used for the treatment of vaginal yeast infections (Candida)." ; rdfs:subClassOf obo:CHEBI_60911 , obo:CHEBI_87071 , obo:CHEBI_87101 . obo:CHEBI_87632 a rdfs:Class ; rdfs:label "statin (naturally occurring)" ; rdfs:comment "Any statin that occurs in nature. The class includes compactin (also known as mevastatin), isolated from a fermentation broth of Penicillium citrinum, and lovastatin, isolated from Aspergillus terreus." ; rdfs:subClassOf obo:CHEBI_87631 . obo:CHEBI_63115 a rdfs:Class ; rdfs:label "fingolimod" ; rdfs:comment "An aminodiol that consists of propane-1,3-diol having amino and 2-(4-octylphenyl)ethyl substituents at the 2-position. It is a sphingosine 1-phosphate receptor modulator used for the treatment of relapsing-remitting multiple sclerosis. A prodrug, fingolimod is phosphorylated by sphingosine kinase to active metabolite fingolimod-phosphate, a structural analogue of sphingosine 1-phosphate." ; rdfs:subClassOf obo:CHEBI_22501 , obo:CHEBI_50994 . obo:CHEBI_64106 a rdfs:Class ; rdfs:label "protein kinase agonist" ; rdfs:comment "An agonist that selectively binds to and activates a protein kinase receptor." ; rdfs:subClassOf obo:CHEBI_48705 . obo:PR_000008300 a rdfs:Class ; rdfs:label "glutathione S-transferase mu 1" ; rdfs:comment "A glutathione S-transferase mu that is a translation product of the human GSTM1 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000029948 . obo:PR_O14656 a rdfs:Class ; rdfs:label "torsin-1A (human)" ; rdfs:comment "A torsin-1A that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000016550 , obo:PR_000029067 . obo:CHEBI_84144 a rdfs:Class ; rdfs:label "L-phenylalanine derivative" ; rdfs:comment "A proteinogenic amino acid derivative resulting from reaction of L-phenylalanine at the amino group or the carboxy group, or from the replacement of any hydrogen of L-phenylalanine by a heteroatom." ; rdfs:subClassOf obo:CHEBI_25985 , obo:CHEBI_83811 . obo:PR_000006310 a rdfs:Class ; rdfs:label "serine/threonine-protein kinase DCLK1" ; rdfs:comment "A doublecortin-like kinase that is a translation product of the human DCLK1 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000050059 . obo:DOID_863 a rdfs:Class ; rdfs:label "nervous system disease" ; rdfs:comment "A disease of anatomical entity that is located_in the central nervous system or located_in the peripheral nervous system." ; rdfs:subClassOf obo:DOID_7 . a rdfs:Class ; rdfs:label "Genital Diseases, Female [Disease/Finding]" ; rdfs:subClassOf . obo:GO_0003008 a rdfs:Class ; rdfs:label "system process" ; rdfs:comment "A multicellular organismal process carried out by any of the organs or tissues in an organ system. An organ system is a regularly interacting or interdependent group of organs or tissues that work together to carry out a biological objective." ; rdfs:subClassOf obo:GO_0032501 . a rdfs:Class ; rdfs:label "Lymphatic Diseases [Disease/Finding]" ; rdfs:subClassOf . obo:PR_Q5EBL8 a rdfs:Class ; rdfs:label "PDZ domain-containing protein 11 (human)" ; rdfs:comment "A PDZ domain-containing protein 11 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000029067 , obo:PR_000029669 . obo:HP_0002017 a rdfs:Class ; rdfs:label "Nausea and vomiting" ; rdfs:comment "Nausea is a commonly encountered symptom that has been defined as an unpleasant painless subjective feeling that one will imminently vomit. Vomiting has been defined as the forceful expulsion of the contents of the stomach, duodenum, or jejunum through the oral cavity. While nausea and vomiting are often thought to exist on a temporal continuum, this is not always the case. There are situations when severe nausea may be present without emesis and less frequently, when emesis may be present without preceding nausea." ; rdfs:subClassOf obo:HP_0011458 . obo:CHEBI_33431 a rdfs:Class ; rdfs:label "elemental chlorine" ; rdfs:subClassOf obo:CHEBI_23117 , obo:CHEBI_33434 . obo:PR_000004528 a rdfs:Class ; rdfs:label "tyrosine-protein kinase receptor UFO" ; rdfs:comment "A protein that is a translation product of the human AXL gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:CHEBI_78616 a rdfs:Class ; rdfs:label "carbohydrates and carbohydrate derivatives" ; rdfs:comment "Any organooxygen compound that is a polyhydroxy-aldehyde or -ketone, or a compound derived from one. Carbohydrates contain only carbon, hydrogen and oxygen and usually have an empirical formula Cm(H2O)n; carbohydrate derivatives may contain other elements by substitution or condensation." ; rdfs:subClassOf obo:CHEBI_36963 . obo:CHEBI_32487 a rdfs:Class ; rdfs:label "L-phenylalaninium" ; rdfs:comment "An optically active form of phenylalaninium having L-configuration." ; rdfs:subClassOf obo:CHEBI_32505 . obo:NCBITaxon_1503304 a rdfs:Class ; rdfs:label "BtTp-BetaCoV/GX2012" ; rdfs:subClassOf obo:NCBITaxon_694007 . obo:CIDO_0000871 a rdfs:Class ; rdfs:label "SARS-CoV2 nsp2 protein binding to human GIGYF2" ; rdfs:comment "SARS-CoV2 nsp2 protein binding to human GIGYF2, as evidented by an affinity-purification mass spectrometry experiment" ; rdfs:subClassOf obo:CIDO_0000580 . obo:PR_O00116 a rdfs:Class ; rdfs:label "alkyldihydroxyacetonephosphate synthase, peroxisomal (human)" ; rdfs:comment "An alkyldihydroxyacetonephosphate synthase, peroxisomal that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000003842 , obo:PR_000029067 . obo:PR_000009897 a rdfs:Class ; rdfs:label "lipoprotein lipase" ; rdfs:comment "A protein that is a translation product of the human LPL gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:NCBITaxon_749429 a rdfs:Class ; rdfs:label "Pintail coronavirus PBA-124" ; rdfs:subClassOf obo:NCBITaxon_749416 . obo:CHEBI_32644 a rdfs:Class ; rdfs:label "methioninate" ; rdfs:comment "A sulfur-containing amino-acid anion that is the conjugate base of methionine, arising from deprotonation of the carboxy group." ; rdfs:subClassOf obo:CHEBI_33558 , obo:CHEBI_63470 . obo:CHEBI_75885 a rdfs:Class ; rdfs:label "2-pyranones" ; rdfs:comment "A pyranone based on the structure of 2H-pyran-2-one and its substituted derivatives." ; rdfs:subClassOf obo:CHEBI_18946 , obo:CHEBI_37963 . obo:CHEBI_50325 a rdfs:Class ; rdfs:label "proteinogenic amino-acid side-chain group" ; rdfs:comment "A univalent organyl group obtained by cleaving the bond from C-2 to the side chain of a proteinogenic amino-acid." ; rdfs:subClassOf obo:CHEBI_33249 . obo:CHEBI_22586 a rdfs:Class ; rdfs:label "antioxidant" ; rdfs:comment "A substance that opposes oxidation or inhibits reactions brought about by dioxygen or peroxides." ; rdfs:subClassOf obo:CHEBI_51086 . obo:CHEBI_36914 a rdfs:Class ; rdfs:label "inorganic ion" ; rdfs:subClassOf obo:CHEBI_24835 , obo:CHEBI_24870 . obo:PR_000029462 a rdfs:Class ; rdfs:label "reticulophagy regulator 3" ; rdfs:comment "A protein that is a translation product of the human RETREG3 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:CHEBI_26469 a rdfs:Class ; rdfs:label "quaternary nitrogen compound" ; rdfs:comment "A nitrogen molecular entity that is electronically neutral but which contains a quaternary nitrogen." ; rdfs:subClassOf obo:CHEBI_35352 . obo:PR_000016456 a rdfs:Class ; rdfs:label "transmembrane protease serine 2" ; rdfs:comment "A protein that is a translation product of the human TMPRSS2 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:PR_000000067 a rdfs:Class ; rdfs:label "activin receptor type-1" ; rdfs:comment "A TGF-beta superfamily receptor type-1 that is a translation product of the human ACVR1 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000006 . obo:PR_000001176 a rdfs:Class ; rdfs:label "D(1B) dopamine receptor" ; rdfs:comment "A D(1)-like dopamine receptor that is a translation product of the human DRD5 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000001107 . obo:CHEBI_38975 a rdfs:Class ; rdfs:label "methylbenzene" ; rdfs:comment "Any alkylbenzene that is benzene substituted with one or more methyl groups." ; rdfs:subClassOf obo:CHEBI_38976 . a rdfs:Class ; rdfs:label "Mental Disorders Diagnosed in Childhood [Disease/Finding]" ; rdfs:subClassOf . obo:PR_P49759 a rdfs:Class ; rdfs:label "dual specificity protein kinase CLK1 (human)" ; rdfs:comment "A dual specificity protein kinase CLK1 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000005584 , obo:PR_000029067 . obo:PR_000002065 a rdfs:Class ; rdfs:label "mast/stem cell growth factor receptor" ; rdfs:comment "A CSF-1/PDGF receptor-type tyrosine-protein kinase that is a translation product of the human KIT gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000001810 . a rdfs:Class ; rdfs:label "DIGOXIN" ; rdfs:subClassOf . obo:HP_0200048 a rdfs:Class ; rdfs:label "Cyanotic episode" ; rdfs:subClassOf obo:HP_0000961 . obo:NCBITaxon_39107 a rdfs:Class ; rdfs:label "Murinae" ; rdfs:subClassOf obo:NCBITaxon_10066 , obo:NCBITaxon_9989 . obo:GO_1903531 a rdfs:Class ; rdfs:label "negative regulation of secretion by cell" ; rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of secretion by cell." ; rdfs:subClassOf obo:GO_0048523 , obo:GO_0051048 , obo:GO_1903530 . obo:VO_0005349 a rdfs:Class ; rdfs:label "Covi Vax"@en ; rdfs:comment "A SARS-CoV-2 inactivated vaccine developed by the National Research Centre of Egypt" ; rdfs:subClassOf obo:VO_0005201 . obo:NCBITaxon_5763 a rdfs:Class ; rdfs:label "Naegleria fowleri" ; rdfs:subClassOf obo:NCBITaxon_5761 . obo:OPMI_0000155 a rdfs:Class ; rdfs:label "health insurance plan"@en ; rdfs:comment "The code in the specific coding system for the payment method of the expenses incurred in a single hospitalization of the patient"@en , "患者单次住院诊疗所发生费用的支付方式的特定编码体系中的代码"@zh ; rdfs:subClassOf obo:IAO_0000104 , obo:OPMI_0000093 . obo:CHEBI_63161 a rdfs:Class ; rdfs:label "glycosyl compound" ; rdfs:comment "A carbohydrate derivative arising formally from the elimination of water from a glycosidic hydroxy group and an H atom bound to an oxygen, carbon, nitrogen or sulfur atom of a separate entity." ; rdfs:subClassOf obo:CHEBI_63299 . obo:CHEBI_76740 a rdfs:Class ; rdfs:label "EC 1.13.* [oxidoreductase acting on single donors with incorporation of molecular oxygen (oxygenases)] inhibitor" ; rdfs:comment "An oxidoreductase inhibitor which interferes with the action of an oxidoreductase acting on single donors with incorporation of molecular oxygen (oxygenases), EC 1.13.*.*." ; rdfs:subClassOf obo:CHEBI_76725 . obo:NCBITaxon_1346314 a rdfs:Class ; rdfs:label "Betacoronavirus BtCoV/Rhi_hip/Slo52/SLO/2009" ; rdfs:subClassOf obo:NCBITaxon_696098 . obo:CIDO_0000939 a rdfs:Class ; rdfs:label "SARS-CoV2 nsp8 protein binding to human NARS2" ; rdfs:comment "SARS-CoV2 nsp8 protein binding to human NARS2, as evidented by an affinity-purification mass spectrometry experiment" ; rdfs:subClassOf obo:CIDO_0000582 . obo:CIDO_0000661 a rdfs:Class ; rdfs:label "D138Y in SARS-CoV-2 S protein" ; rdfs:comment "An AA mutation or AA variant that has mutated an amino acid at position 138 into a tyrosine in S protein." ; rdfs:subClassOf obo:CIDO_0000594 . a rdfs:Class ; rdfs:label "Arthritis [Disease/Finding]" ; rdfs:subClassOf . obo:NCBITaxon_2078986 a rdfs:Class ; rdfs:label "Porcine deltacoronavirus Sichuan" ; rdfs:subClassOf obo:NCBITaxon_1159905 . obo:PR_Q01959 a rdfs:Class ; rdfs:label "sodium-dependent dopamine transporter (human)" ; rdfs:comment "A sodium-dependent dopamine transporter that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000015188 , obo:PR_000029067 . obo:OBI_0001479 a rdfs:Class ; rdfs:label "specimen from organism"@en ; rdfs:comment "A specimen that derives from an anatomical part or substance arising from an organism. Examples of tissue specimen include tissue, organ, physiological system, blood, or body location (arm)." ; rdfs:subClassOf obo:OBI_0100051 . obo:NCBITaxon_349343 a rdfs:Class ; rdfs:label "Bat SARS coronavirus Rp2" ; rdfs:subClassOf obo:NCBITaxon_694009 . obo:NCBITaxon_875615 a rdfs:Class ; rdfs:label "Bat coronavirus HKU9-5-2" ; rdfs:subClassOf obo:NCBITaxon_694006 . obo:CIDO_0000941 a rdfs:Class ; rdfs:label "SARS-CoV2 nsp8 protein binding to human NOL10" ; rdfs:comment "SARS-CoV2 nsp8 protein binding to human NOL10, as evidented by an affinity-purification mass spectrometry experiment" ; rdfs:subClassOf obo:CIDO_0000582 . obo:NCBITaxon_285946 a rdfs:Class ; rdfs:label "SARS coronavirus civet010" ; rdfs:subClassOf obo:NCBITaxon_694009 . obo:CIDO_0000543 a rdfs:Class ; rdfs:label "SAIEDLLFDKVKLSD" ; rdfs:comment "A coronavirus epitope that is part of some S protein from HCoV OC43 composed of the following amino acids SAIEDLLFDKVKLSD" ; rdfs:subClassOf obo:CIDO_0000452 . obo:NCBITaxon_384335 a rdfs:Class ; rdfs:label "Human coronavirus NO" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:NCBITaxon_745733 a rdfs:Class ; rdfs:label "Coronavirus M.das/VM62/2007/NLD" ; rdfs:subClassOf obo:NCBITaxon_696098 . obo:OAE_0000543 a rdfs:Class ; rdfs:label "skin AE" ; rdfs:comment "a hair, skin, and nail AE that occurs in skin." ; rdfs:subClassOf obo:OAE_0000199 . obo:PR_000016874 a rdfs:Class ; rdfs:label "non-receptor tyrosine-protein kinase TYK2" ; rdfs:comment "A Janus kinase that is a translation product of the human TYK2 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000025748 . a rdfs:Class ; rdfs:label "Leukemia, Myelogenous, Chronic, BCR-ABL Positive [Disease/Finding]" ; rdfs:subClassOf , . obo:PR_Q13233 a rdfs:Class ; rdfs:label "mitogen-activated protein kinase kinase kinase 1 (human)" ; rdfs:comment "A mitogen-activated protein kinase kinase kinase 1 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000003215 , obo:PR_000029067 . obo:BFO_0000004 a rdfs:Class ; rdfs:label "independent continuant"@en ; rdfs:comment "b is an independent continuant = Def. b is a continuant which is such that there is no c and no t such that b s-depends_on c at t. (axiom label in BFO2 Reference: [017-002])"@en ; rdfs:subClassOf obo:BFO_0000002 . obo:VO_0005414 a rdfs:Class ; rdfs:label "LVRNA009"@en ; rdfs:comment "A SARS-CoV-2 mRNA vaccine by AIM Vaccine Co., Ltd." ; rdfs:subClassOf obo:VO_0005198 . obo:NCBITaxon_384342 a rdfs:Class ; rdfs:label "Human coronavirus NO/0341/04" ; rdfs:subClassOf obo:NCBITaxon_384335 . a rdfs:Class ; rdfs:label "Pneumovirus Infections [Disease/Finding]" ; rdfs:subClassOf . obo:PR_P29323 a rdfs:Class ; rdfs:label "ephrin type-B receptor 2 (human)" ; rdfs:comment "An ephrin type-B receptor 2 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000007130 , obo:PR_000029067 . obo:NCBITaxon_1269293 a rdfs:Class ; rdfs:label "Coronavirus BtCoV/BRA100/Car_per/BRA/2009" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:NCBITaxon_1895985 a rdfs:Class ; rdfs:label "Camel alphacoronavirus Camel229E" ; rdfs:subClassOf obo:NCBITaxon_11137 . obo:CIDO_0020192 a rdfs:Class ; rdfs:label "LumiraDx SARS-CoV-2 RNA STAR" ; rdfs:seeAlso ; rdfs:subClassOf obo:CIDO_0000454 . obo:GO_0034654 a rdfs:Class ; rdfs:label "nucleobase-containing compound biosynthetic process" ; rdfs:comment "The chemical reactions and pathways resulting in the formation of nucleobases, nucleosides, nucleotides and nucleic acids." ; rdfs:subClassOf obo:GO_0006139 , obo:GO_0018130 , obo:GO_0019438 , obo:GO_0044271 , obo:GO_1901362 . obo:OPMI_0000495 a rdfs:Class ; rdfs:label "home visit"@en ; rdfs:comment "A visit where a provider visits a person, without a care site, within one day, delivering service" ; rdfs:subClassOf obo:OPMI_0000482 . obo:PR_Q92820 a rdfs:Class ; rdfs:label "gamma-glutamyl hydrolase (human)" ; rdfs:comment "A gamma-glutamyl hydrolase that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000007957 , obo:PR_000029067 . obo:CHEBI_44032 a rdfs:Class ; rdfs:label "indinavir" ; rdfs:subClassOf obo:CHEBI_35779 , obo:CHEBI_46851 , obo:CHEBI_46853 . obo:CHEBI_39144 a rdfs:Class ; rdfs:label "Lewis base" ; rdfs:comment "A molecular entity able to provide a pair of electrons and thus capable of forming a covalent bond with an electron-pair acceptor (Lewis acid), thereby producing a Lewis adduct." ; rdfs:subClassOf obo:CHEBI_17891 , obo:CHEBI_22695 . obo:VO_0001146 a rdfs:Class ; rdfs:label "Orthopoxvirus vaccine vector" ; rdfs:comment "a poxvirus vaccine vector that uses an orthopox virus as the vector" ; rdfs:subClassOf obo:VO_0000447 . obo:CHEBI_26288 a rdfs:Class ; rdfs:label "propanediol" ; rdfs:subClassOf obo:CHEBI_13643 . a rdfs:Class ; rdfs:label "Hemangioma [Disease/Finding]" ; rdfs:subClassOf . obo:PR_000000791 a rdfs:Class ; rdfs:label "voltage-gated potassium channel KCNH2" ; rdfs:comment "A voltage-gated potassium channel Erg alpha subunit that is a translation product of the human KCNH2 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000721 . obo:HP_0011702 a rdfs:Class ; rdfs:label "Abnormal electrophysiology of sinoatrial node origin" ; rdfs:comment "An abnormality of the sinoatrial (SA) node in the right atrium. THe SA node acts as the pacemaker of the heart." ; rdfs:subClassOf obo:HP_0011675 . obo:CHEBI_17087 a rdfs:Class ; rdfs:label "ketone" ; rdfs:comment "A compound in which a carbonyl group is bonded to two carbon atoms: R2C=O (neither R may be H)." ; rdfs:subClassOf obo:CHEBI_36586 . obo:CHEBI_24651 a rdfs:Class ; rdfs:label "hydroxides" ; rdfs:comment "Hydroxides are chemical compounds containing a hydroxy group or salts containing hydroxide (OH(-))." ; rdfs:subClassOf obo:CHEBI_25806 , obo:CHEBI_33608 , obo:CHEBI_37577 . obo:CIDO_0000307 a rdfs:Class ; rdfs:label "GLNKVKYATVVVGST"@en ; rdfs:subClassOf obo:CIDO_0000451 . obo:NCBITaxon_1679916 a rdfs:Class ; rdfs:label "Coronavirus RCoV/RMU10_2010/Myo_gla/GER/2010" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:CHEBI_26195 a rdfs:Class ; rdfs:label "polyphenol" ; rdfs:comment "Members of the class of phenols that contain 2 or more benzene rings each of which is substituted by at least one hydroxy group." ; rdfs:subClassOf obo:CHEBI_33853 . obo:CHEBI_189659 a rdfs:Class ; rdfs:label "PF-06446846" ; rdfs:comment "A triazolopyridine that is 3H-[1,2,3]triazolo[4,5-b]pyridine substituted by a 4-{(3-chloropyridin-2-yl)[(3R)-piperidin-3-yl]carbamoyl}phenyl group at position 3. It is a potent inhibitor of PCSK9." ; rdfs:subClassOf obo:CHEBI_140326 , obo:CHEBI_22702 , obo:CHEBI_26151 , obo:CHEBI_39172 , obo:CHEBI_46746 . obo:OBI_0000423 a rdfs:Class ; rdfs:label "extract"@en ; rdfs:comment "an extract is a material entity which results from an extraction process"@en ; rdfs:subClassOf obo:OBI_0000047 . obo:HP_0002315 a rdfs:Class ; rdfs:label "Headache" ; rdfs:comment "Cephalgia, or pain sensed in various parts of the head, not confined to the area of distribution of any nerve." ; rdfs:subClassOf obo:HP_0012638 . obo:CHEBI_38516 a rdfs:Class ; rdfs:label "steroid alkaloid fundamental parent" ; rdfs:subClassOf obo:CHEBI_35506 . obo:GO_0032268 a rdfs:Class ; rdfs:label "regulation of cellular protein metabolic process" ; rdfs:comment "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving a protein, occurring at the level of an individual cell." ; rdfs:subClassOf obo:GO_0031323 , obo:GO_0051246 . obo:CHEBI_8386 a rdfs:Class ; rdfs:label "pregnane" ; rdfs:subClassOf obo:CHEBI_35508 . obo:HP_0011844 a rdfs:Class ; rdfs:label "Abnormal appendicular skeleton morphology" ; rdfs:comment "An abnormality of the appendicular skeletal system, consisting of the of the limbs, shoulder and pelvic girdles." ; rdfs:subClassOf obo:HP_0011842 . a rdfs:Class ; rdfs:label "Biological Response Modifiers [MoA]" ; rdfs:subClassOf . obo:CIDO_0000882 a rdfs:Class ; rdfs:label "SARS-CoV2 nsp4 protein binding to human TIMM29" ; rdfs:comment "SARS-CoV2 nsp4 protein binding to human TIMM29, as evidented by an affinity-purification mass spectrometry experiment" ; rdfs:subClassOf obo:CIDO_0000581 . obo:NCBITaxon_591071 a rdfs:Class ; rdfs:label "Murine coronavirus inf-MHV-A59" ; rdfs:subClassOf obo:NCBITaxon_11138 . a rdfs:Class ; rdfs:label "Lupus Erythematosus, Systemic [Disease/Finding]" ; rdfs:subClassOf , . obo:CHEBI_33572 a rdfs:Class ; rdfs:label "resorcinols" ; rdfs:comment "Any benzenediol in which the two hydroxy groups are meta to one another." ; rdfs:subClassOf obo:CHEBI_33570 . obo:PR_Q9Y6E2 a rdfs:Class ; rdfs:label "eIF5-mimic protein 1 (human)" ; rdfs:comment "An eIF5-mimic protein 1 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000004866 , obo:PR_000029067 . obo:PR_Q00534 a rdfs:Class ; rdfs:label "cyclin-dependent kinase 6 (human)" ; rdfs:comment "A cyclin-dependent kinase 6 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000005264 , obo:PR_000029067 . obo:PR_Q809M3 a rdfs:Class ; rdfs:subClassOf obo:PR_000000001 . obo:PR_000014871 a rdfs:Class ; rdfs:label "serine/threonine-protein kinase SIK2" ; rdfs:comment "A protein that is a translation product of the human SIK2 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:OBI_0000405 a rdfs:Class ; rdfs:label "primer role"@en ; rdfs:comment "a complementary nucleotide probe role which inheres in nucleic acid molecular entity and is realized by the use of the entity bearing the role to initiate chain elongation." ; rdfs:subClassOf obo:OBI_0000857 . obo:HP_0100834 a rdfs:Class ; rdfs:label "Neoplasm of the large intestine" ; rdfs:comment "The presence of a neoplasm of the large intestine." ; rdfs:subClassOf obo:HP_0007378 , obo:HP_0012718 . obo:PR_000006278 a rdfs:Class ; rdfs:label "death-associated protein kinase 3" ; rdfs:comment "A death-associated protein kinase that is a translation product of the human DAPK3 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000029896 . obo:PR_Q96L21 a rdfs:Class ; rdfs:label "60S ribosomal protein L10-like (human)" ; rdfs:comment "A 60S ribosomal protein L10-like that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000014189 , obo:PR_000029067 . obo:CHEBI_30776 a rdfs:Class ; rdfs:label "hexanoic acid" ; rdfs:comment "A C6, straight-chain saturated fatty acid." ; rdfs:subClassOf obo:CHEBI_39418 , obo:CHEBI_59554 . obo:PR_000013434 a rdfs:Class ; rdfs:label "protein-tyrosine kinase 6" ; rdfs:comment "A proto-oncogene SRC-like tyrosine-protein kinase that is a translation product of the human PTK6 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000002997 . obo:NCBITaxon_422137 a rdfs:Class ; rdfs:label "Waterbuck coronavirus US/OH-WD358-TC/1994" ; rdfs:subClassOf obo:NCBITaxon_11128 . a rdfs:Class ; rdfs:label "Hydrocarbons, Cyclic [Chemical/Ingredient]" ; rdfs:subClassOf . obo:GO_1901360 a rdfs:Class ; rdfs:label "organic cyclic compound metabolic process" ; rdfs:comment "The chemical reactions and pathways involving organic cyclic compound." ; rdfs:subClassOf obo:GO_0071704 . obo:NCBITaxon_264988 a rdfs:Class ; rdfs:label "SARS coronavirus sf099" ; rdfs:subClassOf obo:NCBITaxon_694009 . obo:CIDO_0000596 a rdfs:Class ; rdfs:label "AA variant in SARS-CoV-2 N protein"@en ; rdfs:subClassOf obo:CIDO_0000237 . obo:NCBITaxon_627442 a rdfs:Class ; rdfs:label "SARS coronavirus P2" ; rdfs:subClassOf obo:NCBITaxon_694009 . obo:CHEBI_76874 a rdfs:Class ; rdfs:label "EC 2.1.2.* (hydroxymethyl-, formyl- and related transferases) inhibitor" ; rdfs:comment "An EC 2.1.* (C1-transferase) inhibitor that interferes with the action of any hydroxymethyl-, formyl- and related transferase (EC 2.1.2.*)." ; rdfs:subClassOf obo:CHEBI_76655 . a rdfs:Class ; rdfs:label "Autoimmune Diseases of the Nervous System [Disease/Finding]" ; rdfs:subClassOf , . obo:NCBITaxon_2501927 a rdfs:Class ; rdfs:label "Myotis ricketti alphacoronavirus Sax-2011" ; rdfs:subClassOf obo:NCBITaxon_2509500 . obo:CHEBI_13248 a rdfs:Class ; rdfs:label "anilide" ; rdfs:comment "Any aromatic amide obtained by acylation of aniline." ; rdfs:subClassOf obo:CHEBI_22712 , obo:CHEBI_62733 . obo:GO_0044419 a rdfs:Class ; rdfs:label "biological process involved in interspecies interaction between organisms" ; rdfs:comment "Any process evolved to enable an interaction with an organism of a different species." ; rdfs:subClassOf obo:GO_0008150 . obo:BFO_0000015 a rdfs:Class ; rdfs:label "process"@en ; rdfs:comment "p is a process = Def. p is an occurrent that has temporal proper parts and for some time t, p s-depends_on some material entity at t. (axiom label in BFO2 Reference: [083-003])"@en ; rdfs:subClassOf obo:BFO_0000003 . obo:CHEBI_32651 a rdfs:Class ; rdfs:label "L-asparaginium" ; rdfs:subClassOf obo:CHEBI_32661 . obo:APOLLO_SV_00000327 a rdfs:Class ; rdfs:label "quarantine control strategy"@en ; rdfs:subClassOf obo:APOLLO_SV_00000086 . obo:CHEBI_25235 a rdfs:Class ; rdfs:label "monomethoxybenzene" ; rdfs:comment "Compounds containing a benzene skeleton substituted with one methoxy group." ; rdfs:subClassOf obo:CHEBI_51683 . a rdfs:Class ; rdfs:label "Peptides [Chemical/Ingredient]" ; rdfs:subClassOf . obo:CIDO_0001134 a rdfs:Class ; rdfs:label "SARS-CoV2 orf8 protein binding to human SDF2"@en ; rdfs:comment "SARS-CoV2 orf8 protein binding to human SDF2, as evidented by an affinity-purification mass spectrometry experiment" ; rdfs:subClassOf obo:CIDO_0000051 . a rdfs:Class ; rdfs:label "HIV Infections [Disease/Finding]" ; rdfs:subClassOf , , . a rdfs:Class ; rdfs:label "Histamine Receptor Antagonists [MoA]" ; rdfs:subClassOf . obo:UBERON_0001264 a rdfs:Class ; rdfs:label "pancreas" ; rdfs:comment "An endoderm derived structure that produces precursors of digestive enzymes and blood glucose regulating enzymes[GO]." ; rdfs:subClassOf obo:UBERON_0000465 . a rdfs:Class ; rdfs:label "Histamine Activity Alteration [PE]" ; rdfs:subClassOf . obo:GO_0007212 a rdfs:Class ; rdfs:label "dopamine receptor signaling pathway" ; rdfs:comment "The series of molecular signals generated as a consequence of a dopamine receptor binding to one of its physiological ligands." ; rdfs:subClassOf obo:GO_0007165 . obo:CHEBI_38653 a rdfs:Class ; rdfs:label "methylbutyric acid" ; rdfs:comment "A methyl-branched fatty acid comprising a butyric acid core carrying a single methyl substituent." ; rdfs:subClassOf obo:CHEBI_26666 , obo:CHEBI_39417 , obo:CHEBI_62499 . obo:NCBITaxon_267399 a rdfs:Class ; rdfs:label "SARS coronavirus Sin3408L" ; rdfs:subClassOf obo:NCBITaxon_694009 . a rdfs:Class ; rdfs:label "Brain Damage, Chronic [Disease/Finding]" ; rdfs:subClassOf . obo:VO_0010754 a rdfs:Class ; rdfs:label "virus protein" ; rdfs:comment "a protein from a virus" ; rdfs:subClassOf obo:PR_000000001 . obo:CHEBI_50949 a rdfs:Class ; rdfs:label "serotonin uptake inhibitor" ; rdfs:comment "A compound that specifically inhibits the reuptake of serotonin in the brain. This increases the serotonin concentration in the synaptic cleft which then activates serotonin receptors to a greater extent." ; rdfs:subClassOf obo:CHEBI_48278 . obo:CIDO_0000462 a rdfs:Class ; rdfs:label "APDGLLFLHTVLLPT" ; rdfs:comment "A coronavirus epitope that is part of some S protein from HCoV NL63 composed of the following amino acids APDGLLFLHTVLLPT" ; rdfs:subClassOf obo:CIDO_0000449 . a rdfs:Class ; rdfs:label "Adrenal Cortical Activity Alteration [PE]" ; rdfs:subClassOf . obo:CIDO_0001013 a rdfs:Class ; rdfs:label "BNT162c2 SARS-CoV-2 Vaccine" ; rdfs:subClassOf obo:CHEBI_23367 . obo:CHEBI_60004 a rdfs:Class ; rdfs:label "mixture" ; rdfs:comment "A mixture is a chemical substance composed of multiple molecules, at least two of which are of a different kind." ; rdfs:subClassOf obo:CHEBI_59999 . obo:CIDO_0001160 a rdfs:Class ; rdfs:label "AA variant in SARS-CoV-2 S protein S2 FPR region"@en ; rdfs:subClassOf obo:CIDO_0000595 . obo:CIDO_0000997 a rdfs:Class ; rdfs:label "SARS-CoV2 orf8 protein binding to human ERP44" ; rdfs:comment "SARS-CoV2 orf8 protein binding to human ERP44, as evidented by an affinity-purification mass spectrometry experiment" ; rdfs:subClassOf obo:CIDO_0000051 . obo:CHEBI_40303 a rdfs:Class ; rdfs:label "lovastatin" ; rdfs:comment "A fatty acid ester that is mevastatin carrying an additional methyl group on the carbobicyclic skeleton. It is used in as an anticholesteremic drug and has been found in fungal species such as Aspergillus terreus and Pleurotus ostreatus (oyster mushroom)." ; rdfs:subClassOf obo:CHEBI_142348 , obo:CHEBI_18946 , obo:CHEBI_26188 , obo:CHEBI_35748 , obo:CHEBI_87632 . obo:GO_0048524 a rdfs:Class ; rdfs:label "positive regulation of viral process" ; rdfs:comment "Any process that activates or increases the frequency, rate or extent of a multi-organism process in which a virus is a participant." ; rdfs:subClassOf obo:GO_0048518 , obo:GO_0050792 . obo:CHEBI_2896 a rdfs:Class ; rdfs:label "astemizole" ; rdfs:comment "A piperidine compound having a 2-(4-methoxyphenyl)ethyl group at the 1-position and an N-[(4-fluorobenzyl)benzimidazol-2-yl]amino group at the 4-position." ; rdfs:subClassOf obo:CHEBI_22715 , obo:CHEBI_26151 . a rdfs:Class ; rdfs:label "Pregnancy [Disease/Finding]" ; rdfs:subClassOf . obo:DOID_0050161 a rdfs:Class ; rdfs:label "lower respiratory tract disease" ; rdfs:comment "A respiratory system disease which involves the lower respiratory tract." ; rdfs:subClassOf obo:DOID_1579 . obo:CHEBI_145565 a rdfs:Class ; rdfs:label "macrolide lactam" ; rdfs:comment "A macrolide in which the macrocyclic lactone ring includes an amide group." ; rdfs:subClassOf obo:CHEBI_24995 , obo:CHEBI_25106 . obo:GO_0022836 a rdfs:Class ; rdfs:label "gated channel activity" ; rdfs:comment "Enables the transmembrane transfer of a solute by a channel that opens in response to a specific stimulus." ; rdfs:subClassOf obo:GO_0015267 . obo:NCBITaxon_903618 a rdfs:Class ; rdfs:label "Kenya bat coronavirus BtKY80" ; rdfs:subClassOf obo:NCBITaxon_2664420 . a rdfs:Class ; rdfs:label "Esophageal Achalasia [Disease/Finding]" ; rdfs:subClassOf . obo:CIDO_0000499 a rdfs:Class ; rdfs:label "KRGEKGAYNKDHGRG" ; rdfs:comment "A coronavirus epitope that is part of some S protein from HCoV OC43 composed of the following amino acids KRGEKGAYNKDHGRG" ; rdfs:subClassOf obo:CIDO_0000452 . obo:CHEBI_26979 a rdfs:Class ; rdfs:label "organic heterotricyclic compound" ; rdfs:comment "An organic tricyclic compound in which at least one of the rings of the tricyclic skeleton contains one or more heteroatoms." ; rdfs:subClassOf obo:CHEBI_36688 , obo:CHEBI_38166 , obo:CHEBI_51959 . obo:GO_1903530 a rdfs:Class ; rdfs:label "regulation of secretion by cell" ; rdfs:comment "Any process that modulates the frequency, rate or extent of secretion by cell." ; rdfs:subClassOf obo:GO_0050794 , obo:GO_0051046 . a rdfs:Class ; rdfs:label "TRIFLUPROMAZINE HYDROCHLORIDE" ; rdfs:subClassOf . obo:CIDO_0020299 a rdfs:Class ; rdfs:label "Solana SARS-CoV-2 Assay" ; rdfs:seeAlso ; rdfs:subClassOf obo:CIDO_0000454 . obo:DOID_11328 a rdfs:Class ; rdfs:label "schizophreniform disorder" ; rdfs:comment "A psychotic disorder that involves schizophrenia symptoms over time period of one month." ; rdfs:subClassOf obo:DOID_2468 . obo:PR_000013219 a rdfs:Class ; rdfs:label "5'-AMP-activated protein kinase catalytic subunit alpha-2" ; rdfs:comment "A protein that is a translation product of the human PRKAA2 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:PR_000000072 a rdfs:Class ; rdfs:label "activin/inhibin beta subunit" ; rdfs:comment "A TGF-beta-like cystine-knot cytokine that is the beta subunit of inhibin and activin complexes. Related to the transforming growth factor-beta, anti-Muellerian hormone, and bone morphogenic protein families which are all involved in the regulation of cell growth and differentiation." ; rdfs:subClassOf obo:PR_000000008 . obo:CIDO_0020105 a rdfs:Class ; rdfs:label "CRSP SARS-CoV-2 Real-time Reverse Transcriptase (RT)-PCR Diagnostic Assay (Version 3)" ; rdfs:seeAlso ; rdfs:subClassOf obo:CIDO_0000454 . obo:NCBITaxon_59479 a rdfs:Class ; rdfs:label "Rhinolophus ferrumequinum" ; rdfs:subClassOf obo:NCBITaxon_49442 . obo:CHEBI_35358 a rdfs:Class ; rdfs:label "sulfonamide" ; rdfs:comment "An amide of a sulfonic acid RS(=O)2NR'2." ; rdfs:subClassOf obo:CHEBI_33256 , obo:CHEBI_33261 , obo:CHEBI_33552 . obo:APOLLO_SV_00000412 a rdfs:Class ; rdfs:label "leakage rate of Wolbachia infection in mosquito population infected with Wolbachia"@en ; rdfs:comment "The rate at which offspring of the Wolbachia-infected female mosquito subpopulation (of the overall mosquito population) are not infected with Wolbachia."@en ; rdfs:subClassOf obo:OBI_0001554 . obo:CHEBI_26463 a rdfs:Class ; rdfs:label "pyruvate family amino acid" ; rdfs:comment "An L-alpha-amino acid which is biosynthesised from pyruvate (i.e. alanine, valine, and leucine). A closed class." ; rdfs:subClassOf obo:CHEBI_15705 , obo:CHEBI_83813 . obo:NCBITaxon_2042584 a rdfs:Class ; rdfs:label "Coronavirus PREDICT CoV-60" ; rdfs:subClassOf obo:NCBITaxon_366617 . obo:CHEBI_48357 a rdfs:Class ; rdfs:label "aprotic solvent" ; rdfs:subClassOf obo:CHEBI_46787 . obo:NCBITaxon_1415834 a rdfs:Class ; rdfs:label "Bat SARS-like coronavirus Rs3367" ; rdfs:subClassOf obo:NCBITaxon_694009 . obo:OPMI_0000473 a rdfs:Class ; rdfs:label "year of birth"@en ; rdfs:comment "A year when an organism (e.g., a human) is born." ; rdfs:subClassOf obo:BFO_0000038 , obo:OPMI_0000478 . obo:CIDO_0000918 a rdfs:Class ; rdfs:label "SARS-CoV2 nsp7 protein binding to human RHOA" ; rdfs:comment "SARS-CoV2 nsp7 protein binding to human RHOA, as evidented by an affinity-purification mass spectrometry experiment" ; rdfs:subClassOf obo:CIDO_0000049 . obo:UBERON_0000117 a rdfs:Class ; rdfs:label "respiratory tube" ; rdfs:comment "A tube in the respiratory system. Examples: bronchus, bronchiole, trachea." ; rdfs:subClassOf obo:UBERON_0004119 , obo:UBERON_0010000 . obo:PR_000030840 a rdfs:Class ; rdfs:label "CDGSH iron-sulfur domain-containing protein 3, mitochondrial" ; rdfs:comment "A protein that is a translation product of the human CISD3 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:VO_0005169 a rdfs:Class ; rdfs:label "GRAd-COV2" ; rdfs:comment "A SARS-CoV 2 recombinant viral vector using Gorilla Adenovirus that encodes for SARS-CoV-2 Spike protein." ; rdfs:subClassOf obo:VO_0005200 . obo:CHEBI_36841 a rdfs:Class ; rdfs:label "11-hydroxy steroid" ; rdfs:subClassOf obo:CHEBI_35350 . obo:NCBITaxon_33154 a rdfs:Class ; rdfs:label "Opisthokonta" ; rdfs:subClassOf obo:NCBITaxon_2759 . obo:CIDO_0000419 a rdfs:Class ; rdfs:label "human coronavirus patient"@en ; rdfs:comment "a human patient who is infected with coronavirus" ; rdfs:subClassOf obo:OPMI_0000417 . obo:NCBITaxon_756645 a rdfs:Class ; rdfs:label "Bovine coronavirus cow/WDBR-978/BRA/2003" ; rdfs:subClassOf obo:NCBITaxon_11128 . obo:VO_0005118 a rdfs:Class ; rdfs:label "MERS England1 S1 protein subunit Vaccine" ; rdfs:comment "A MERS DNA vaccine made of plasmid that encoded S1 subunit only" ; rdfs:subClassOf obo:VO_0004900 . obo:CHEBI_76725 a rdfs:Class ; rdfs:label "EC 1.* (oxidoreductase) inhibitor" ; rdfs:comment "An enzyme inhibitor which interferes with the action of an oxidoreductase (EC 1.*.*.*)." ; rdfs:subClassOf obo:CHEBI_23924 . a rdfs:Class ; rdfs:label "Mental Disorders and Manifestations [Disease/Finding]" ; rdfs:subClassOf . obo:OAE_0000361 a rdfs:Class ; rdfs:label "fever AE" ; rdfs:comment "an abnormal body temperature AE which has an outcome of fever" ; rdfs:subClassOf obo:OAE_0000624 . a rdfs:Class ; rdfs:label "Small Intestine Fluid/Electrolyte Alteration [PE]" ; rdfs:subClassOf . obo:CHEBI_83038 a rdfs:Class ; rdfs:label "Daphnia galeata metabolite" ; rdfs:comment "A Daphnia metabolite produced by the species Daphnia galeata." ; rdfs:subClassOf obo:CHEBI_83057 . obo:UBERON_0000473 a rdfs:Class ; rdfs:label "testis" ; rdfs:comment "A gonad of a male animal. A gonad produces and releases sperm." ; rdfs:subClassOf obo:UBERON_0000465 . obo:CHEBI_50846 a rdfs:Class ; rdfs:label "immunomodulator" ; rdfs:comment "Biologically active substance whose activity affects or plays a role in the functioning of the immune system." ; rdfs:subClassOf obo:CHEBI_23888 , obo:CHEBI_24432 . obo:CIDO_0000117 a rdfs:Class ; rdfs:label "chemical role against coronavirus assembly"@en ; rdfs:subClassOf obo:CIDO_0000072 . obo:HP_0004757 a rdfs:Class ; rdfs:label "Paroxysmal atrial fibrillation" ; rdfs:comment "Episodes of atrial fibrillation that typically last for several hours up to one day and terminate spontaneously." ; rdfs:subClassOf obo:HP_0005110 . obo:CHEBI_38932 a rdfs:Class ; rdfs:label "pyridopyrimidine" ; rdfs:comment "Any organic heterobicyclic compound consisting of a pyridine ring ortho-fused at any position to a pyrimidine ring." ; rdfs:subClassOf obo:CHEBI_27171 . obo:PR_P27105 a rdfs:Class ; rdfs:label "stomatin (human)" ; rdfs:comment "A stomatin that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000015763 , obo:PR_000029067 . obo:CIDO_0000811 a rdfs:Class ; rdfs:label "SARS-CoV2 nsp12 protein binding to human PRRC2B" ; rdfs:comment "SARS-CoV2 nsp12 protein binding to human PRRC2B, as evidented by an affinity-purification mass spectrometry experiment" ; rdfs:subClassOf obo:CIDO_0000057 . obo:CHEBI_4031 a rdfs:Class ; rdfs:label "cyclosporin A" ; rdfs:comment "A cyclic nonribosomal peptide of eleven amino acids; an immunosuppressant drug widely used in post-allogeneic organ transplant to reduce the activity of the patient's immune system, and therefore the risk of organ rejection. Also causes reversible inhibition of immunocompetent lymphocytes in the G0- and G1-phase of the cell cycle." ; rdfs:subClassOf obo:CHEBI_24613 . obo:NCBITaxon_749424 a rdfs:Class ; rdfs:label "Brent goose coronavirus KR-70" ; rdfs:subClassOf obo:NCBITaxon_749416 . obo:CHEBI_38825 a rdfs:Class ; rdfs:label "tetrafluoromethane" ; rdfs:subClassOf obo:CHEBI_38824 , obo:CHEBI_39281 . obo:GO_1901685 a rdfs:Class ; rdfs:label "glutathione derivative metabolic process" ; rdfs:comment "The chemical reactions and pathways involving glutathione derivative." ; rdfs:subClassOf obo:GO_0006790 , obo:GO_1901564 . obo:CHEBI_133538 a rdfs:Class ; rdfs:label "L-lysine zwitterion" ; rdfs:comment "An L-alpha-amino acid zwitterion obtained by transfer of a proton from the carboxy to the amino group of L-lysine; major species at pH 7.3." ; rdfs:subClassOf obo:CHEBI_59869 . obo:ENVO_01000815 a rdfs:Class ; rdfs:label "liquid environmental material"@en ; rdfs:comment "An environmental material which is in a liquid state." ; rdfs:subClassOf obo:ENVO_00010483 , obo:ENVO_02000140 . obo:PR_P54760 a rdfs:Class ; rdfs:label "ephrin type-B receptor 4 (human)" ; rdfs:comment "An ephrin type-B receptor 4 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000007132 , obo:PR_000029067 . obo:CHEBI_145503 a rdfs:Class ; rdfs:label "(S)-donepezil(1+)" ; rdfs:subClassOf obo:CHEBI_48633 . obo:PR_P49841 a rdfs:Class ; rdfs:label "glycogen synthase kinase-3 beta (human)" ; rdfs:comment "A glycogen synthase kinase-3 beta that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000008288 , obo:PR_000029067 . obo:CHEBI_37700 a rdfs:Class ; rdfs:label "EC 2.7.11.13 (protein kinase C) inhibitor" ; rdfs:comment "An EC 2.7.11.* (protein-serine/threonine kinase) inhibitor that interferes with the action of protein kinase C (EC 2.7.11.13)." ; rdfs:subClassOf obo:CHEBI_76812 . obo:CHEBI_62733 a rdfs:Class ; rdfs:label "aromatic amide" ; rdfs:comment "An amide in which the amide linkage is bonded directly to an aromatic system." ; rdfs:subClassOf obo:CHEBI_32988 , obo:CHEBI_33659 . obo:NCBITaxon_249069 a rdfs:Class ; rdfs:label "SARS coronavirus HSZ-A" ; rdfs:subClassOf obo:NCBITaxon_694009 . obo:CHEBI_74223 a rdfs:Class ; rdfs:label "pyrrolidin-2-ones" ; rdfs:comment "A pyrrolidinone in which the oxo group is at position 2 of the pyrrolidine ring." ; rdfs:subClassOf obo:CHEBI_38275 , obo:CHEBI_74222 . obo:UBERON_0001013 a rdfs:Class ; rdfs:label "adipose tissue" ; rdfs:comment "Portion of connective tissue composed of adipocytes enmeshed in areolar tissue" ; rdfs:subClassOf obo:UBERON_0000479 . obo:CHEBI_73024 a rdfs:Class ; rdfs:label "O-acetylcarnitine" ; rdfs:comment "An O-acylcarnitine having acetyl as the acyl substituent." ; rdfs:subClassOf obo:CHEBI_17387 . obo:NCBITaxon_2501961 a rdfs:Class ; rdfs:label "Bat Hp-betacoronavirus Zhejiang2013" ; rdfs:subClassOf obo:NCBITaxon_2509486 . obo:CHEBI_39279 a rdfs:Class ; rdfs:label "halomethane" ; rdfs:comment "A haloalkane that is methane in which one (or more) of the hydrogens have been replaced by a halogen atom/halogen atoms." ; rdfs:subClassOf obo:CHEBI_24469 , obo:CHEBI_64708 . obo:GO_0009967 a rdfs:Class ; rdfs:label "positive regulation of signal transduction" ; rdfs:comment "Any process that activates or increases the frequency, rate or extent of signal transduction." ; rdfs:subClassOf obo:GO_0009966 , obo:GO_0010647 , obo:GO_0023056 , obo:GO_0048584 . obo:NCBITaxon_864591 a rdfs:Class ; rdfs:label "Bat coronavirus BB98-18/BGR/2008" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:CHEBI_139592 a rdfs:Class ; rdfs:label "tertiary alpha-hydroxy ketone" ; rdfs:comment "An alpha-hydroxy ketone in which the carbonyl group and the hydroxy group are linked by a carbon bearing two organyl groups." ; rdfs:subClassOf obo:CHEBI_139588 , obo:CHEBI_26878 . obo:NCBITaxon_1897074 a rdfs:Class ; rdfs:label "Bat coronavirus Glo.sor/100/BRA/2014" ; rdfs:subClassOf obo:NCBITaxon_366617 . obo:CIDO_0020008 a rdfs:Class ; rdfs:label "Advanta Dx SARS-CoV-2 RT-PCR Assay" ; rdfs:seeAlso ; rdfs:subClassOf obo:CIDO_0000454 . obo:CHEBI_17478 a rdfs:Class ; rdfs:label "aldehyde" ; rdfs:comment "A compound RC(=O)H, in which a carbonyl group is bonded to one hydrogen atom and to one R group." ; rdfs:subClassOf obo:CHEBI_36586 . obo:NCBITaxon_1679881 a rdfs:Class ; rdfs:label "Coronavirus Hare_CoV/La08_99/Lep_gra/ESP/2008" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:PR_Q8NBX0 a rdfs:Class ; rdfs:label "saccharopine dehydrogenase-like oxidoreductase (human)" ; rdfs:comment "A saccharopine dehydrogenase-like oxidoreductase that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000029067 , obo:PR_000029749 . obo:CHEBI_48377 a rdfs:Class ; rdfs:label "imidic acid" ; rdfs:comment "Compounds derived from oxoacids RkE(=O)l(OH)m (l =/= 0) by replacing =O by =NR; thus tautomers of amides. In organic chemistry an unspecified imidic acid is generally a carboximidic acid, RC(=NR)(OH)." ; rdfs:subClassOf obo:CHEBI_33241 , obo:CHEBI_51143 . obo:VO_0005269 a rdfs:Class ; rdfs:label "authorized COVID-19 subunit vaccine"@en ; rdfs:subClassOf obo:VO_0005202 , obo:VO_0005264 . obo:NCBITaxon_1076295 a rdfs:Class ; rdfs:label "Ferret coronavirus 511c" ; rdfs:subClassOf obo:NCBITaxon_366617 . obo:GO_0032880 a rdfs:Class ; rdfs:label "regulation of protein localization" ; rdfs:comment "Any process that modulates the frequency, rate or extent of any process in which a protein is transported to, or maintained in, a specific location." ; rdfs:subClassOf obo:GO_0032879 . obo:CIDO_0000930 a rdfs:Class ; rdfs:label "SARS-CoV2 nsp8 protein binding to human EXOSC8" ; rdfs:comment "SARS-CoV2 nsp8 protein binding to human EXOSC8, as evidented by an affinity-purification mass spectrometry experiment" ; rdfs:subClassOf obo:CIDO_0000582 . obo:PR_000007536 a rdfs:Class ; rdfs:label "peptidyl-prolyl cis-trans isomerase FKBP1A" ; rdfs:comment "A protein that is a translation product of the human FKBP1A gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:CHEBI_61777 a rdfs:Class ; rdfs:label "terpene glycoside" ; rdfs:comment "A terpenoid in which one or more hydroxy functions are glycosylated." ; rdfs:subClassOf obo:CHEBI_24400 , obo:CHEBI_26873 . obo:CIDO_0001002 a rdfs:Class ; rdfs:label "Triazavirin" ; rdfs:subClassOf obo:CHEBI_23367 . obo:CHEBI_138675 a rdfs:Class ; rdfs:label "gas molecular entity" ; rdfs:comment "Any main group molecular entity that is gaseous at standard temperature and pressure (STP; 0degreeC and 100 kPa)." ; rdfs:subClassOf obo:CHEBI_33579 . obo:NCBITaxon_864613 a rdfs:Class ; rdfs:label "Bat coronavirus BR98-31/BGR/2008" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:CHEBI_57757 a rdfs:Class ; rdfs:label "D-threonine zwitterion" ; rdfs:comment "A D-alpha-amino acid zwitterion that is D-threonine in which a proton has been transferred from the carboxy group to the amino group. It is the major species at pH 7.3." ; rdfs:subClassOf obo:CHEBI_59871 . obo:GO_0006810 a rdfs:Class ; rdfs:label "transport" ; rdfs:comment "The directed movement of substances (such as macromolecules, small molecules, ions) or cellular components (such as complexes and organelles) into, out of or within a cell, or between cells, or within a multicellular organism by means of some agent such as a transporter, pore or motor protein." ; rdfs:subClassOf obo:GO_0051234 . obo:CHEBI_5435 a rdfs:Class ; rdfs:label "piperidine-2,6-dione" ; rdfs:comment "A dicarboximide that is piperidine which is substituted by oxo groups at positions 2 and 6." ; rdfs:subClassOf obo:CHEBI_35356 , obo:CHEBI_48589 . obo:GO_0048513 a rdfs:Class ; rdfs:label "animal organ development" ; rdfs:comment "Development of a tissue or tissues that work together to perform a specific function or functions. Development pertains to the process whose specific outcome is the progression of a structure over time, from its formation to the mature structure. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions." ; rdfs:subClassOf obo:GO_0048856 . a rdfs:Class ; rdfs:label "Colitis [Disease/Finding]" ; rdfs:subClassOf , . obo:CHEBI_26830 a rdfs:Class ; rdfs:label "sulfonium compound" ; rdfs:subClassOf obo:CHEBI_26835 . obo:NCBITaxon_1868635 a rdfs:Class ; rdfs:label "Bat coronavirus/2218/2014/Cynomops planirostris/Brazil" ; rdfs:subClassOf obo:NCBITaxon_366617 . obo:HP_0011893 a rdfs:Class ; rdfs:label "Abnormal leukocyte count" ; rdfs:comment "Number of leukocytes per volume of blood beyond normal limits." ; rdfs:subClassOf obo:HP_0001881 . obo:NCBITaxon_1868639 a rdfs:Class ; rdfs:label "Bat coronavirus/4702/2013/Cynomops abrasus/Brazil" ; rdfs:subClassOf obo:NCBITaxon_366617 . obo:NCBITaxon_264371 a rdfs:Class ; rdfs:label "SARS coronavirus TW-HP1" ; rdfs:subClassOf obo:NCBITaxon_264370 . obo:PR_Q12907 a rdfs:Class ; rdfs:label "vesicular integral-membrane protein VIP36 (human)" ; rdfs:comment "A vesicular integral-membrane protein VIP36 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000009852 , obo:PR_000029067 . obo:CIDO_0000565 a rdfs:Class ; rdfs:label "WFNTMLDASAPATGW" ; rdfs:comment "A coronavirus epitope that is part of some S protein from HCoV HKU1 composed of the following amino acids WFNTMLDASAPATGW" ; rdfs:subClassOf obo:CIDO_0000450 . obo:PR_000029749 a rdfs:Class ; rdfs:label "saccharopine dehydrogenase-like oxidoreductase" ; rdfs:comment "A protein that is a translation product of the human SCCPDH gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . a rdfs:Class ; rdfs:label "PROMETHAZINE HYDROCHLORIDE" ; rdfs:subClassOf . obo:CHEBI_33281 a rdfs:Class ; rdfs:label "antimicrobial agent" ; rdfs:comment "A substance that kills or slows the growth of microorganisms, including bacteria, viruses, fungi and protozoans." ; rdfs:subClassOf obo:CHEBI_24432 . obo:CHEBI_35191 a rdfs:Class ; rdfs:label "triterpene" ; rdfs:comment "A C30 terpene." ; rdfs:subClassOf obo:CHEBI_35186 . obo:GO_0010628 a rdfs:Class ; rdfs:label "positive regulation of gene expression" ; rdfs:comment "Any process that increases the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product (protein or RNA)." ; rdfs:subClassOf obo:GO_0010468 , obo:GO_0010604 . obo:NCBITaxon_422135 a rdfs:Class ; rdfs:label "Waterbuck coronavirus US/OH-WD358/1994" ; rdfs:subClassOf obo:NCBITaxon_11128 . obo:CIDO_0020113 a rdfs:Class ; rdfs:label "DiaSorin LIAISON SARS-CoV-2 IgM Assay" ; rdfs:seeAlso ; rdfs:subClassOf obo:CIDO_0000454 . obo:HP_0001871 a rdfs:Class ; rdfs:label "Abnormality of blood and blood-forming tissues" ; rdfs:comment "An abnormality of the hematopoietic system." ; rdfs:subClassOf obo:HP_0000118 . obo:CIDO_0020211 a rdfs:Class ; rdfs:label "NeuMoDx SARS-CoV-2 Assay" ; rdfs:seeAlso ; rdfs:subClassOf obo:CIDO_0000454 . obo:CHEBI_66902 a rdfs:Class ; rdfs:label "CFTR potentiator" ; rdfs:comment "A membrane transport modulator that restores the chloride ion transport ability of defective cystic fibrosis transmembrane conductance regulator (CFTR) genes." ; rdfs:subClassOf obo:CHEBI_38632 . obo:PR_Q9NZJ7 a rdfs:Class ; rdfs:label "mitochondrial carrier homolog 1 (human)" ; rdfs:comment "A mitochondrial carrier homolog 1 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000010712 , obo:PR_000029067 . obo:CIDO_0020292 a rdfs:Class ; rdfs:label "Simoa SARS-CoV-2 N Protein Antigen Test" ; rdfs:seeAlso ; rdfs:subClassOf obo:CIDO_0000454 . obo:GO_0003018 a rdfs:Class ; rdfs:label "vascular process in circulatory system" ; rdfs:comment "A circulatory process that occurs at the level of the vasculature." ; rdfs:subClassOf obo:GO_0003008 . obo:PR_000008478 a rdfs:Class ; rdfs:label "histone deacetylase 1" ; rdfs:comment "A protein that is a translation product of the human HDAC1 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:GO_0051239 a rdfs:Class ; rdfs:label "regulation of multicellular organismal process" ; rdfs:comment "Any process that modulates the frequency, rate or extent of a multicellular organismal process, the processes pertinent to the function of a multicellular organism above the cellular level; includes the integrated processes of tissues and organs." ; rdfs:subClassOf obo:GO_0050789 . obo:NCBITaxon_2341010 a rdfs:Class ; rdfs:label "Guinea fowl coronavirus" ; rdfs:subClassOf obo:NCBITaxon_749416 . obo:CHEBI_17203 a rdfs:Class ; rdfs:label "L-proline" ; rdfs:comment "Pyrrolidine in which the pro-S hydrogen at position 2 is substituted by a carboxylic acid group. L-Proline is the only one of the twenty DNA-encoded amino acids which has a secondary amino group alpha to the carboxyl group. It is an essential component of collagen and is important for proper functioning of joints and tendons. It also helps maintain and strengthen heart muscles." ; rdfs:subClassOf obo:CHEBI_15705 , obo:CHEBI_24318 , obo:CHEBI_26271 , obo:CHEBI_83813 . obo:NCBITaxon_983925 a rdfs:Class ; rdfs:label "Rousettus bat coronavirus/Kenya/KY06/2006" ; rdfs:subClassOf obo:NCBITaxon_696098 . obo:OAE_0000582 a rdfs:Class ; rdfs:label "sensory capability AE" ; rdfs:comment "a behavior and neurological AE that has an outcome of inability or altered ability to respond to a sensory stimulus"@en ; rdfs:subClassOf obo:OAE_0000580 . obo:CIDO_0000268 a rdfs:Class ; rdfs:label "mast cell activation disorder"@en ; rdfs:comment "A leakocyte disease with a disorder in the mast cell activation." ; rdfs:subClassOf obo:DOID_9500 . obo:NCBITaxon_314145 a rdfs:Class ; rdfs:label "Laurasiatheria" ; rdfs:subClassOf obo:NCBITaxon_1437010 . obo:OAE_0004526 a rdfs:Class ; rdfs:label "Injection site swelling AE"@en ; rdfs:comment "an adverse event that displays swelling at the injection site" ; rdfs:subClassOf obo:OAE_0000366 . obo:PR_P23921 a rdfs:Class ; rdfs:label "ribonucleoside-diphosphate reductase large subunit (human)" ; rdfs:comment "A ribonucleoside-diphosphate reductase large subunit that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000014305 , obo:PR_000029067 . obo:CIDO_0001210 a rdfs:Class ; rdfs:label "Multiple Real-Time PCR Kit for Detection of 2019-nCoV. (BGI BIOTECHNOLOGY (WUHAN) Co., Ltd.)" ; rdfs:comment "Scope of application/Intended use: This kit is used for in vitro qualitative detection of novel coronavirus (2019-nCoV) in throat swabs and bronchoalveolar lavage fluid samples of suspected novel coronavirus pneumonia cases, clustered cases, and other patients who need to be diagnosed or differentially diagnosed with novel coronavirus infection. ) ORF1ab gene." ; rdfs:subClassOf obo:CIDO_0000021 . obo:VO_0000599 a rdfs:Class ; rdfs:label "recombinant vaccine vector" ; rdfs:subClassOf obo:VO_0000179 . obo:NCBITaxon_1644142 a rdfs:Class ; rdfs:label "Bat coronavirus MAH051F" ; rdfs:subClassOf obo:NCBITaxon_696098 . obo:GO_0009725 a rdfs:Class ; rdfs:label "response to hormone" ; rdfs:comment "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hormone stimulus." ; rdfs:subClassOf obo:GO_0009719 , obo:GO_0010033 . obo:CIDO_0000683 a rdfs:Class ; rdfs:label "N969K in SARS-CoV-2 S protein" ; rdfs:comment "An AA mutation or AA variant that has mutated an amino acid at position 969 into a lysine in S protein." ; rdfs:subClassOf obo:CIDO_0001161 . a rdfs:Class ; rdfs:label "Decreased Dopamine Activity [PE]" ; rdfs:subClassOf . obo:DRON_00018901 a rdfs:Class ; rdfs:label "dasatinib" ; rdfs:subClassOf obo:OBI_0000047 . obo:CIDO_0000132 a rdf:Property ; rdfs:label "drug has protein target as potentiator"@en ; rdfs:comment "An object property that represents a relation between a drug and a protein where the drug can target the protein as a potentiator. In clinical pharmacology, a potentiator is a drug, herb, or chemical that intensifies the effects of a given drug or protein regulator." ; rdfs:range ; rdfs:subPropertyOf obo:CIDO_0000124 . obo:CHEBI_32564 a rdfs:Class ; rdfs:label "lysinium(1+)" ; rdfs:comment "An alpha-amino-acid cation that is the conjugate acid of lysine, having two cationic amino groups and an anionic carboxy group." ; rdfs:subClassOf obo:CHEBI_33719 . obo:PR_000001096 a rdfs:Class ; rdfs:label "Toll-like receptor" ; rdfs:comment "A protein with a core domain composition consisting of a signal peptide, an extracellular domain with multiple Leucine rich repeat (Pfam:PF13855) domain (LRR), a cysteine-rich region, a single-pass transmembrane domain and a C-terminal cytoplasmic tail containing a TIR domain (Pfam:PF01582)." ; rdfs:subClassOf obo:PR_000000001 . a rdfs:Class ; rdfs:label "Endometriosis [Disease/Finding]" ; rdfs:subClassOf . obo:CHEBI_76924 a rdfs:Class ; rdfs:label "plant metabolite" ; rdfs:comment "Any eukaryotic metabolite produced during a metabolic reaction in plants, the kingdom that include flowering plants, conifers and other gymnosperms." ; rdfs:subClassOf obo:CHEBI_75763 . obo:CIDO_0000844 a rdfs:Class ; rdfs:label "SARS-CoV2 nsp13 protein binding to human GRIPAP1" ; rdfs:comment "SARS-CoV2 nsp13 protein binding to human GRIPAP1, as evidented by an affinity-purification mass spectrometry experiment" ; rdfs:subClassOf obo:CIDO_0000058 . obo:NCBITaxon_1763410 a rdfs:Class ; rdfs:label "European turkey coronavirus 080385d" ; rdfs:subClassOf obo:NCBITaxon_694014 . obo:PR_O15530 a rdfs:Class ; rdfs:label "3-phosphoinositide-dependent protein kinase 1 (human)" ; rdfs:comment "A 3-phosphoinositide-dependent protein kinase 1 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000012515 , obo:PR_000029067 . obo:PR_000050269 a rdfs:Class ; rdfs:label "spike protein S2' (SARS-CoV-2)" ; rdfs:comment "A spike protein S2 (SARS-CoV-2) that has been further processed by proteolytic cleavage to yield the C-terminal portion. UniProtKB:P0DTC2, 816-1273." ; rdfs:subClassOf obo:PR_000050268 . obo:CHEBI_73413 a rdfs:Class ; rdfs:label "cannabinoid receptor antagonist" ; rdfs:comment "An antagonist that binds to and deactivates cannabinoid receptors." ; rdfs:subClassOf obo:CHEBI_48706 . obo:CIDO_0000437 a rdfs:Class ; rdfs:label "negative COVID-19 diagnosis conclusion"@en ; rdfs:comment "The representation of a negative conclusion of a diagnostic process for the COVID-19 coronavirus disease." ; rdfs:subClassOf obo:CIDO_0000430 . obo:CIDO_0000495 a rdfs:Class ; rdfs:label "ELDQWFKNQTSVAPD" ; rdfs:comment "A coronavirus epitope that is part of some S protein from HCoV OC43 composed of the following amino acids ELDQWFKNQTSVAPD" ; rdfs:subClassOf obo:CIDO_0000452 . obo:PR_000013240 a rdfs:Class ; rdfs:label "cGMP-dependent protein kinase 2" ; rdfs:comment "A protein that is a translation product of the human PRKG2 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:OBI_0002605 a rdfs:Class ; rdfs:label "cheek swab specimen" ; rdfs:comment "A specimen that is collected with a swab from the cheek portion of the inside surface of a mouth." ; rdfs:subClassOf obo:OBI_0002599 . obo:NCBITaxon_249084 a rdfs:Class ; rdfs:label "SARS coronavirus LC2" ; rdfs:subClassOf obo:NCBITaxon_694009 . obo:HP_0002099 a rdfs:Class ; rdfs:label "Asthma" ; rdfs:comment "Asthma is characterized by increased responsiveness of the tracheobronchial tree to multiple stimuli, leading to narrowing of the air passages with resultant dyspnea, cough, and wheezing." ; rdfs:subClassOf obo:HP_0002795 , obo:HP_0100326 . obo:CHEBI_189652 a rdfs:Class ; rdfs:label "MZ1" ; rdfs:subClassOf obo:CHEBI_50860 . obo:CIDO_0000045 a rdf:Property ; rdfs:label "chemical degrades protein"@en ; rdfs:comment "An object property that represents a relation between a chemical entity and a protein where the chemical entity can degrate the protein." ; rdfs:range ; rdfs:subPropertyOf obo:CIDO_0000118 . obo:DRON_00014863 a rdfs:Class ; rdfs:label "Hexachlorophene" ; rdfs:subClassOf obo:OBI_0000047 . obo:CHEBI_25367 a rdfs:Class ; rdfs:label "molecule" ; rdfs:comment "Any polyatomic entity that is an electrically neutral entity consisting of more than one atom." ; rdfs:subClassOf obo:CHEBI_36357 . obo:GO_0031280 a rdfs:Class ; rdfs:label "negative regulation of cyclase activity" ; rdfs:comment "Any process that stops or reduces the activity of a cyclase." ; rdfs:subClassOf obo:GO_0031279 , obo:GO_0043086 . obo:CIDO_0001105 a rdfs:Class ; rdfs:label "SARS-CoV2 orf8 protein binding to human SMOC1" ; rdfs:comment "SARS-CoV2 orf8 protein binding to human SMOC1, as evidented by an affinity-purification mass spectrometry experiment" ; rdfs:subClassOf obo:CIDO_0000051 . obo:HP_0003003 a rdfs:Class ; rdfs:label "Colon cancer" ; rdfs:subClassOf obo:HP_0100834 . obo:DRON_00013779 a rdfs:Class ; rdfs:label "mycophenolate mofetil" ; rdfs:subClassOf obo:OBI_0000047 . obo:VO_0005094 a rdfs:Class ; rdfs:label "RBD-HBsAg VLP"@en ; rdfs:comment "A SARS-CoV-2 virus-like particle vaccine that contains the Receptor Binding Domain (RBD) of the SARS-CoV-2 spike (S) protein and is adjuvanted with aluminum." ; rdfs:subClassOf obo:VO_0005205 . obo:CHEBI_33252 a rdfs:Class ; rdfs:label "atomic nucleus" ; rdfs:comment "A nucleus is the positively charged central portion of an atom, excluding the orbital electrons." ; rdfs:subClassOf obo:CHEBI_36347 . obo:NCBITaxon_293934 a rdfs:Class ; rdfs:label "SARS coronavirus PC4-13" ; rdfs:subClassOf obo:NCBITaxon_694009 . obo:NCBITaxon_1415830 a rdfs:Class ; rdfs:label "Bat SARS-like coronavirus Rs3262-1" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:VO_0000278 a rdfs:Class ; rdfs:label "vaccine function" ; rdfs:comment "vaccine function is a function that inheres in a vaccine that induces protective immune response against a disease. It is realized in the immunization process in the host."@en ; rdfs:subClassOf obo:BFO_0000034 . a rdfs:Class ; rdfs:label "Neoplasms, Hormone-Dependent [Disease/Finding]" ; rdfs:subClassOf . obo:OBI_0002540 a rdfs:Class ; rdfs:label "coronary artery specimen" ; rdfs:comment "A specimen that is derived from coronary artery." ; rdfs:subClassOf obo:OBI_0001479 . obo:NCBITaxon_2030446 a rdfs:Class ; rdfs:label "Coronavirus HKU23" ; rdfs:subClassOf obo:NCBITaxon_694003 . obo:PR_000010999 a rdfs:Class ; rdfs:label "probable N-acetyltransferase 14" ; rdfs:comment "A protein that is a translation product of the human NAT14 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:CIDO_0000574 a rdfs:Class ; rdfs:label "GTFESAAAGTFVLDM" ; rdfs:comment "A coronavirus epitope that is part of some S protein from HCoV NL63 composed of the following amino acids GTFESAAAGTFVLDM" ; rdfs:subClassOf obo:CIDO_0000449 . a rdfs:Class ; rdfs:label "Disorganized Electrical Activity Alteration [PE]" ; rdfs:subClassOf . obo:CIDO_0001096 a rdfs:Class ; rdfs:label "SARS-CoV2 orf8 protein binding to human STC2"@en ; rdfs:comment "SARS-CoV2 orf8 protein binding to human STC2, as evidented by an affinity-purification mass spectrometry experiment" ; rdfs:subClassOf obo:CIDO_0000051 . obo:PR_000007362 a rdfs:Class ; rdfs:label "fibrillin-1" ; rdfs:comment "A protein that is a translation product of the human FBN1 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . a rdfs:Class ; rdfs:label "Psychotic Disorders [Disease/Finding]" ; rdfs:subClassOf . obo:VO_0005171 a rdfs:Class ; rdfs:label "KBP-COVID-19"@en ; rdfs:comment "A SARS-CoV-2 subunit vaccine that is made of a protein subunit made of the RBD domain of the S protein." ; rdfs:subClassOf obo:VO_0005202 . obo:PR_000013150 a rdfs:Class ; rdfs:label "calcineurin subunit B type 1" ; rdfs:comment "A protein that is a translation product of the human PPP3R1 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:PR_000017284 a rdfs:Class ; rdfs:label "vascular endothelial growth factor A" ; rdfs:comment "A protein that is a translation product of the human VEGFA gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:CHEBI_25094 a rdfs:Class ; rdfs:label "lysine" ; rdfs:comment "A diamino acid that is caproic (hexanoic) acid bearing two amino substituents at positions 2 and 6." ; rdfs:subClassOf obo:CHEBI_26167 , obo:CHEBI_33704 , obo:CHEBI_35987 . obo:NCBITaxon_1477414 a rdfs:Class ; rdfs:label "Deltacoronavirus PDCoV/USA/Ohio137/2014" ; rdfs:subClassOf obo:NCBITaxon_1159905 . obo:CIDO_0000963 a rdfs:Class ; rdfs:label "SARS-CoV2 orf10 protein binding to human CUL2" ; rdfs:comment "SARS-CoV2 orf10 protein binding to human CUL2, as evidented by an affinity-purification mass spectrometry experiment" ; rdfs:subClassOf obo:CIDO_0000050 . obo:PR_000050380 a rdfs:Class ; rdfs:label "AAK1 gene translation product (human)" ; rdfs:comment "An AAK1 gene translation product that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000003526 , obo:PR_000029067 . a rdfs:Class ; rdfs:label "Physiological Effects [PE]" ; rdfs:subClassOf obo:BFO_0000015 . obo:GO_0007207 a rdfs:Class ; rdfs:label "phospholipase C-activating G protein-coupled acetylcholine receptor signaling pathway" ; rdfs:comment "A phospholipase C-activating G protein-coupled receptor signaling pathway initiated by acetylcholine binding to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription." ; rdfs:subClassOf obo:GO_0007200 , obo:GO_0007213 . obo:PR_000003660 a rdfs:Class ; rdfs:label "fatty acid CoA ligase Acsl3" ; rdfs:comment "A protein that is a translation product of the human ACSL3 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:VO_0010850 a rdfs:Class ; rdfs:label "SARS-CoV protein" ; rdfs:subClassOf obo:PR_000000001 , obo:VO_0010754 . obo:NCBITaxon_2730119 a rdfs:Class ; rdfs:label "unclassified Orthocoronavirinae" ; rdfs:subClassOf obo:NCBITaxon_2501931 . obo:CIDO_0000404 a rdfs:Class ; rdfs:label "SARS-CoV-2 P.1.2 virus"@en ; rdfs:subClassOf obo:CIDO_0000406 . a rdfs:Class ; rdfs:label "Site of Metabolism [PK]" ; rdfs:subClassOf . obo:NCBITaxon_1897079 a rdfs:Class ; rdfs:label "Bat coronavirus Stu.lil/1573/BRA/2012" ; rdfs:subClassOf obo:NCBITaxon_366617 . obo:CHEBI_50127 a rdfs:Class ; rdfs:label "trifluoromethyl group" ; rdfs:subClassOf obo:CHEBI_50491 . obo:CIDO_0000852 a rdfs:Class ; rdfs:label "SARS-CoV2 nsp13 protein binding to human PDE4DIP" ; rdfs:comment "SARS-CoV2 nsp13 protein binding to human PDE4DIP, as evidented by an affinity-purification mass spectrometry experiment" ; rdfs:subClassOf obo:CIDO_0000058 . obo:NCBITaxon_1289553 a rdfs:Class ; rdfs:label "Coronavirus Mex_CoV-7" ; rdfs:subClassOf obo:NCBITaxon_366617 . obo:HP_0002823 a rdfs:Class ; rdfs:label "Abnormality of femur morphology" ; rdfs:comment "Any anomaly of the structure of the femur." ; rdfs:subClassOf obo:HP_0040069 . a rdfs:Class ; rdfs:label "Decreased Acetylcholine Activity [PE]" ; rdfs:subClassOf . obo:CHEBI_35471 a rdfs:Class ; rdfs:label "psychotropic drug" ; rdfs:comment "A loosely defined grouping of drugs that have effects on psychological function." ; rdfs:subClassOf obo:CHEBI_35470 . obo:CIDO_0000672 a rdfs:Class ; rdfs:label "G496S in SARS-CoV-2 S protein" ; rdfs:comment "An AA mutation or AA variant that has mutated an amino acid at position 496 into a serine in S protein." ; rdfs:subClassOf obo:CIDO_0000593 . obo:CIDO_0020153 a rdfs:Class ; rdfs:label "GENETWORx Covid-19 Nasal Swab Test" ; rdfs:seeAlso ; rdfs:subClassOf obo:CIDO_0000455 . obo:NCBITaxon_698398 a rdfs:Class ; rdfs:label "recombinant SARSr-CoV" ; rdfs:subClassOf obo:NCBITaxon_694009 . obo:CHEBI_24648 a rdfs:Class ; rdfs:label "hydroxamic acid anion" ; rdfs:comment "An oxoanion resulting from the removal of a proton from the hydroxy group of any hydroxamic acid." ; rdfs:subClassOf obo:CHEBI_25696 , obo:CHEBI_35406 . obo:NCBITaxon_550974 a rdfs:Class ; rdfs:label "Bat coronavirus R.meg/Australia/CoV100/2007" ; rdfs:subClassOf obo:NCBITaxon_366617 . obo:PR_000017821 a rdfs:Class ; rdfs:label "zinc finger protein 318" ; rdfs:comment "A protein that is a translation product of the human ZNF318 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:DRON_00000059 a rdfs:Class ; rdfs:subClassOf obo:BFO_0000016 . obo:NCBITaxon_1269317 a rdfs:Class ; rdfs:label "Coronavirus BtCoV/KP817/Phy_dis/PAN/2011" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:OBI_0200166 a rdfs:Class ; rdfs:label "data transformation objective"@en ; rdfs:comment "An objective specification to transformation input data into output data"@en ; rdfs:subClassOf obo:IAO_0000005 . obo:CHEBI_33241 a rdfs:Class ; rdfs:label "oxoacid derivative" ; rdfs:subClassOf obo:CHEBI_37577 . obo:CHEBI_32457 a rdfs:Class ; rdfs:label "cysteinate(2-)" ; rdfs:subClassOf obo:CHEBI_33558 . obo:CHEBI_35221 a rdfs:Class ; rdfs:label "antimetabolite" ; rdfs:comment "A substance which is structurally similar to a metabolite but which competes with it or replaces it, and so prevents or reduces its normal utilization." ; rdfs:subClassOf obo:CHEBI_52206 . obo:CIDO_0001079 a rdfs:Class ; rdfs:label "AA variant in SARS-CoV-2 nsp8 protein"@en ; rdfs:comment "An AA variant in SARS-CoV-2 nsp8 protein. Equivalent to an AA variant in SARS-CoV-2 rep 1ab with an AA position of 3920 - 4117." ; rdfs:subClassOf obo:CIDO_0000714 . obo:CIDO_0001156 a rdfs:Class ; rdfs:label "AA variant in SARS-CoV-2 protein SD2 S1 region"@en ; rdfs:subClassOf obo:CIDO_0000592 . obo:CHEBI_24261 a rdfs:Class ; rdfs:label "glucocorticoid" ; rdfs:comment "Glucocorticoids are a class of steroid hormones that regulate a variety of physiological processes, in particular control of the concentration of glucose in blood." ; rdfs:subClassOf obo:CHEBI_36699 . obo:NCBITaxon_240273 a rdfs:Class ; rdfs:label "SARS coronavirus ZMY 1" ; rdfs:subClassOf obo:NCBITaxon_694009 . obo:GO_1903727 a rdfs:Class ; rdfs:label "positive regulation of phospholipid metabolic process" ; rdfs:comment "Any process that activates or increases the frequency, rate or extent of phospholipid metabolic process." ; rdfs:subClassOf obo:GO_0045834 , obo:GO_0045937 , obo:GO_1903725 . obo:OPMI_0000576 a rdfs:Class ; rdfs:label "observation temporal region"@en ; rdfs:comment "A temporal region that is associated with an observation" ; rdfs:subClassOf obo:BFO_0000008 . obo:PR_P07359 a rdfs:Class ; rdfs:label "platelet glycoprotein Ib alpha chain (human)" ; rdfs:comment "A platelet glycoprotein Ib alpha chain that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000001907 , obo:PR_000029067 . obo:GO_0044062 a rdfs:Class ; rdfs:label "regulation of excretion" ; rdfs:comment "Any process that modulates the frequency, rate, or extent of excretion, the elimination by an organism of the waste products that arise as a result of metabolic activity." ; rdfs:subClassOf obo:GO_0044057 , obo:GO_0051046 . obo:CHEBI_50176 a rdfs:Class ; rdfs:label "keratolytic drug" ; rdfs:comment "A drug that softens, separates, and causes desquamation of the cornified epithelium or horny layer of skin. Keratolytic drugs are used to expose mycelia of infecting fungi or to treat corns, warts, and certain other skin diseases." ; rdfs:subClassOf obo:CHEBI_50177 . obo:HP_0040182 a rdfs:Class ; rdfs:label "Inappropriate sinus tachycardia" ; rdfs:comment "Inappropriate sinus tachycardia is a nonparoxysmal tachyarrhythmia characterized by an increased resting heart rate (HR) and/or an exaggerated HR response to minimal exertion or a change in body posture. HR is constantly above the physiological range with no appropriate relation to metabolic or physiological demands." ; rdfs:subClassOf obo:HP_0011703 . obo:PR_000012785 a rdfs:Class ; rdfs:label "serine/threonine-protein kinase N1" ; rdfs:comment "A protein that is a translation product of the human PKN1 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:UBERON_0000945 a rdfs:Class ; rdfs:label "stomach" ; rdfs:comment "An expanded region of the vertebrate alimentary tract that serves as a food storage compartment and digestive organ. A stomach is lined, in whole or in part by a glandular epithelium." ; rdfs:subClassOf obo:UBERON_0000062 , obo:UBERON_0000465 , obo:UBERON_0004921 . obo:CIDO_0000554 a rdfs:Class ; rdfs:label "NQLRLAFLGASVTED" ; rdfs:comment "A coronavirus epitope that is part of some S protein from HCoV NL63 composed of the following amino acids NQLRLAFLGASVTED" ; rdfs:subClassOf obo:CIDO_0000449 . obo:OBCS_0000094 a rdfs:Class ; rdfs:label "disease test sensitivity" ; rdfs:comment "A sensitivity that refers to the number of patients with a positive test who have a disease divided by all patients who have the disease. A test with high sensitivity will not miss many patients who have the disease (i.e., few false negative results)." ; rdfs:subClassOf obo:OBCS_0000058 . obo:CHEBI_15138 a rdfs:Class ; rdfs:label "sulfide(2-)" ; rdfs:comment "A divalent inorganic anion obtained by removal of both protons from hydrogen sulfide." ; rdfs:subClassOf obo:CHEBI_79388 . obo:PR_Q5BJF2 a rdfs:Class ; rdfs:label "sigma intracellular receptor 2 (human)" ; rdfs:comment "A sigma intracellular receptor 2 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000029067 , obo:PR_000032038 . obo:PR_000010146 a rdfs:Class ; rdfs:label "mitogen-activated protein kinase kinase kinase kinase 5" ; rdfs:comment "A protein that is a translation product of the human MAP4K5 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:NCBITaxon_2042566 a rdfs:Class ; rdfs:label "Coronavirus PREDICT CoV-40" ; rdfs:subClassOf obo:NCBITaxon_366617 . obo:NCBITaxon_741998 a rdfs:Class ; rdfs:label "Bat SARS coronavirus HKU3-11" ; rdfs:subClassOf obo:NCBITaxon_442736 . obo:OBI_0002599 a rdfs:Class ; rdfs:label "swab specimen" ; rdfs:comment "A specimen that is stored on a swab as the output of a collecting specimen with swab process." ; rdfs:subClassOf obo:OBI_0100051 . obo:CIDO_0000905 a rdfs:Class ; rdfs:label "SARS-CoV2 nsp7 protein binding to human NAT14" ; rdfs:comment "SARS-CoV2 nsp7 protein binding to human NAT14, as evidented by an affinity-purification mass spectrometry experiment" ; rdfs:subClassOf obo:CIDO_0000049 . obo:PR_000012870 a rdfs:Class ; rdfs:label "serine/threonine-protein kinase PLK1" ; rdfs:comment "A protein that is a translation product of the human PLK1 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:OBI_0000848 a rdfs:Class ; rdfs:label "polyA RNA extraction" ; rdfs:comment "A RNA extraction process typically involving the use of poly dT oligomers in which the desired output material is polyA RNA." ; rdfs:subClassOf obo:OBI_0666666 . obo:DOID_331 a rdfs:Class ; rdfs:label "central nervous system disease" ; rdfs:comment "A nervous system disease that affects either the spinal cord (myelopathy) or brain (encephalopathy) of the central nervous system." ; rdfs:subClassOf obo:DOID_863 . obo:CHEBI_38867 a rdfs:Class ; rdfs:label "anaesthetic" ; rdfs:comment "Substance which produces loss of feeling or sensation." ; rdfs:subClassOf obo:CHEBI_23888 . obo:PR_P61011 a rdfs:Class ; rdfs:label "signal recognition particle 54 kDa protein (human)" ; rdfs:comment "A signal recognition particle 54 kDa protein that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000015625 , obo:PR_000029067 . obo:CHEBI_18140 a rdfs:Class ; rdfs:label "hydrogen halide" ; rdfs:subClassOf obo:CHEBI_33405 . obo:PR_000029055 a rdfs:Class ; rdfs:label "Saccharomyces cerevisiae protein" ; rdfs:comment "A protein that is encoded in the genome of Saccharomyces cerevisiae." ; rdfs:subClassOf obo:PR_000036194 . obo:PR_P84098 a rdfs:Class ; rdfs:label "60S ribosomal protein L19 (human)" ; rdfs:comment "A 60S ribosomal protein L19 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000014199 , obo:PR_000029067 . obo:CIDO_0000579 a rdfs:Class ; rdfs:label "YEYYVKWPWYVWLLI" ; rdfs:comment "A coronavirus epitope that is part of some S protein from HCoV OC43 composed of the following amino acids YEYYVKWPWYVWLLI" ; rdfs:subClassOf obo:CIDO_0000452 . obo:NCBITaxon_1479610 a rdfs:Class ; rdfs:label "Dromedary camel coronavirus HKU23" ; rdfs:subClassOf obo:NCBITaxon_2030446 . a rdfs:Class ; rdfs:label "Immunologic Adjuvants [MoA]" ; rdfs:subClassOf . obo:GO_0045937 a rdfs:Class ; rdfs:label "positive regulation of phosphate metabolic process" ; rdfs:comment "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving phosphates." ; rdfs:subClassOf obo:GO_0010562 , obo:GO_0019220 . obo:PR_000000004 a rdfs:Class ; rdfs:label "RING-box protein" ; rdfs:comment "A protein with a core domain composition consisting of a Zinc finger, C3HC4 type (RING finger)(Pfam:PF00097) domain." ; rdfs:subClassOf obo:PR_000000001 . obo:NCBITaxon_1297662 a rdfs:Class ; rdfs:label "Thrush coronavirus HKU12" ; rdfs:subClassOf obo:NCBITaxon_1159901 . obo:VO_0000211 a rdfs:Class ; rdfs:label "vaccine organism inactivated" ; rdfs:comment "an organismal quality of a whole organism vaccine where the whole organism is inactivated/killed and lacks the capability of replication. " ; rdfs:subClassOf obo:VO_0001139 . obo:NCBITaxon_633140 a rdfs:Class ; rdfs:label "SARS coronavirus MA15 ExoN1" ; rdfs:subClassOf obo:NCBITaxon_698398 . obo:PR_P01189 a rdfs:Class ; rdfs:label "pro-opiomelanocortin (human)" ; rdfs:comment "A pro-opiomelanocortin that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000013015 , obo:PR_000029067 . obo:OBI_0002527 a rdfs:Class ; rdfs:label "pancreas specimen" ; rdfs:comment "A specimen that is derived from pancreas." ; rdfs:subClassOf obo:OBI_0001479 . obo:GO_0071071 a rdfs:Class ; rdfs:label "regulation of phospholipid biosynthetic process" ; rdfs:comment "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of phospholipids." ; rdfs:subClassOf obo:GO_0031326 , obo:GO_0046890 , obo:GO_1903725 . a rdfs:Class ; rdfs:label "Drug Hypersensitivity [Disease/Finding]" ; rdfs:subClassOf . obo:NCBITaxon_1487702 a rdfs:Class ; rdfs:label "Myotis davidii coronavirus" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:CHEBI_64678 a rdfs:Class ; rdfs:label "anthracycline cation" ; rdfs:comment "An organic cation obtained by protonation of any anthracycline." ; rdfs:subClassOf obo:CHEBI_25697 , obo:CHEBI_35274 . obo:CHEBI_105516 a rdfs:Class ; rdfs:label "N-[4-[[1-[2-(3,4-dimethoxyphenyl)ethyl]-2,4,6-trioxo-1,3-diazinan-5-ylidene]methylamino]phenyl]acetamide" ; rdfs:subClassOf obo:CHEBI_13248 , obo:CHEBI_22160 . obo:CIDO_0001024 a rdfs:Class ; rdfs:label "Azvudine" ; rdfs:subClassOf obo:CHEBI_23367 . obo:NCBITaxon_389152 a rdfs:Class ; rdfs:label "Bat coronavirus (BtCoV/A897/2005)" ; rdfs:subClassOf obo:NCBITaxon_389126 . obo:PR_P42684 a rdfs:Class ; rdfs:label "tyrosine-protein kinase ABL2 (human)" ; rdfs:comment "A tyrosine-protein kinase ABL2 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000003583 , obo:PR_000029067 . obo:CHEBI_63551 a rdfs:Class ; rdfs:label "carbohydrate acid derivative anion" ; rdfs:comment "A carboxylic acid anion resulting from the deprotonation of the carboxy group of a carbohydrate acid derivative." ; rdfs:subClassOf obo:CHEBI_29067 . obo:CHEBI_16042 a rdfs:Class ; rdfs:label "halide anion" ; rdfs:comment "A monoatomic monoanion resulting from the addition of an electron to any halogen atom." ; rdfs:subClassOf obo:CHEBI_33429 , obo:CHEBI_79389 . obo:PR_P80192 a rdfs:Class ; rdfs:label "mitogen-activated protein kinase kinase kinase 9 (human)" ; rdfs:comment "A mitogen-activated protein kinase kinase kinase 9 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000010141 , obo:PR_000029067 . obo:OAE_0001448 a rdfs:Class ; rdfs:label "thrombocytopenia AE" ; rdfs:comment "a hematopoietic system AE that has an outcome of decrease in platelets in the blood" ; rdfs:subClassOf obo:OAE_0000085 , obo:OAE_0000588 . a rdfs:Class ; rdfs:label "Sulfur Compounds [Chemical/Ingredient]" ; rdfs:subClassOf , . obo:VO_0005099 a rdfs:Class ; rdfs:label "VLA2001"@en ; rdfs:comment "A SARS-CoV-2 inactivated, Vero-cell based vaccine adjuvanted with aluminum and CpG 1018. It uses the manufacturing platform of Valneva’s commercial Japanese encephalitis (JE) vaccine" ; rdfs:subClassOf obo:VO_0005266 . obo:CIDO_0001145 a rdfs:Class ; rdfs:label "SARS-CoV-2 S1 protein amino acid deletion"@en ; rdfs:comment "A SARS-CoV-2 protein AA deletion that affected a SARS-CoV-2 S protein in the S1 domain." ; rdfs:subClassOf obo:CIDO_0001144 . obo:CIDO_0000484 a rdfs:Class ; rdfs:label "FSFGKVNNFVKFGSV" ; rdfs:comment "A coronavirus epitope that is part of some S protein from HCoV 229E composed of the following amino acids FSFGKVNNFVKFGSV" ; rdfs:subClassOf obo:CIDO_0000451 . obo:CIDO_0020270 a rdfs:Class ; rdfs:label "SARS-CoV-2 DETECTR Reagent Kit" ; rdfs:seeAlso ; rdfs:subClassOf obo:CIDO_0000454 . obo:OPMI_0000543 a rdfs:Class ; rdfs:label "cause of death status"@en ; rdfs:comment "A cause of death is an official determination of conditions resulting in a human's death, which may be recorded on a death certificate. A cause of death is determined by a medical examiner." ; rdfs:subClassOf obo:OPMI_0000533 . a rdfs:Class ; rdfs:label "Decreased Eicosanoid Activity [PE]" ; rdfs:subClassOf . obo:PR_000012925 a rdfs:Class ; rdfs:label "pancreatic triacylglycerol lipase" ; rdfs:comment "A protein that is a translation product of the human PNLIP gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:CIDO_0020339 a rdfs:Class ; rdfs:label "Xpert Xpress SARS-CoV-2 test" ; rdfs:seeAlso ; rdfs:subClassOf obo:CIDO_0000454 . a rdfs:Class ; rdfs:label "Decreased DNA Replication [PE]" ; rdfs:subClassOf . obo:NCBITaxon_264385 a rdfs:Class ; rdfs:label "SARS coronavirus TW-YM3" ; rdfs:subClassOf obo:NCBITaxon_264370 . obo:CIDO_0000833 a rdfs:Class ; rdfs:label "SARS-CoV2 nsp13 protein binding to human CIT" ; rdfs:comment "SARS-CoV2 nsp13 protein binding to human CIT, as evidented by an affinity-purification mass spectrometry experiment" ; rdfs:subClassOf obo:CIDO_0000058 . obo:PR_000050270 a rdfs:Class ; rdfs:label "host translation inhibitor nsp1 (SARS-CoV-2)" ; rdfs:comment "A rep gene proteolytic cleavage product (SARS-CoV-2) that is the N-terminal portion produced by the enzymatic action of PL-PRO proteinase (nsp3) when it cleaves the precursor rep gene translation product (SARS-CoV-2) between residues 180-181." ; rdfs:subClassOf obo:PR_000050281 . obo:PR_000012743 a rdfs:Class ; rdfs:label "phosphatidylinositol 5-phosphate 4-kinase type-2 gamma" ; rdfs:comment "A protein that is a translation product of the human PIP4K2C gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . a rdfs:Class ; rdfs:label "Decreased Leukotriene Activity [PE]" ; rdfs:subClassOf . obo:CHEBI_8461 a rdfs:Class ; rdfs:label "promethazine" ; rdfs:comment "A substituted phenothiazine in which the ring nitrogen at position 10 is attached to C-3 of an N,N-dimethylpropan-2-amine moiety." ; rdfs:subClassOf obo:CHEBI_32876 , obo:CHEBI_38093 . obo:GO_0031328 a rdfs:Class ; rdfs:label "positive regulation of cellular biosynthetic process" ; rdfs:comment "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of substances, carried out by individual cells." ; rdfs:subClassOf obo:GO_0009891 , obo:GO_0031325 , obo:GO_0031326 . obo:NCBITaxon_1508224 a rdfs:Class ; rdfs:label "Lucheng Rn rat coronavirus" ; rdfs:subClassOf obo:NCBITaxon_2509492 . obo:VO_0005247 a rdfs:Class ; rdfs:label "V-01"@en ; rdfs:comment "A SARS-CoV-2 subunit vaccine developed by Livzon Mabpharm Inc." ; rdfs:subClassOf obo:VO_0005202 . obo:PR_000049994 a rdfs:Class ; rdfs:label "histamine receptor" ; rdfs:comment "A rhodopsin-like G-protein coupled receptor that is a translation product of the human HRH1 to HRH4 genes, 1:1 orthologs thereof, or a semi-ortholog thereof." ; rdfs:subClassOf obo:PR_000001094 . obo:CHEBI_35296 a rdfs:Class ; rdfs:label "ortho-fused polycyclic arene" ; rdfs:subClassOf obo:CHEBI_33848 , obo:CHEBI_35427 . obo:VO_0005338 a rdfs:Class ; rdfs:label "SCTV01C"@en ; rdfs:comment "A SARS-CoV-2 subunit vaccine by Sinocelltech Ltd." ; rdfs:subClassOf obo:VO_0005202 . obo:PR_P30291 a rdfs:Class ; rdfs:label "Wee1-like protein kinase (human)" ; rdfs:comment "A Wee1-like protein kinase that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000017403 , obo:PR_000029067 . obo:NCBITaxon_989337 a rdfs:Class ; rdfs:label "Zaria bat coronavirus" ; rdfs:subClassOf obo:NCBITaxon_2729735 . obo:CHEBI_50837 a rdfs:Class ; rdfs:label "estrogen antagonist" ; rdfs:comment "A compound which inhibits or antagonises the biosynthesis or actions of estrogens." ; rdfs:subClassOf obo:CHEBI_49020 . obo:CIDO_0000348 a rdfs:Class ; rdfs:label "host-SARS-CoV-2 protein-protein interaction"@en ; rdfs:subClassOf obo:CIDO_0000195 . obo:GO_0048149 a rdfs:Class ; rdfs:label "behavioral response to ethanol" ; rdfs:comment "Any process that results in a change in the behavior of an organism as a result of an ethanol stimulus." ; rdfs:subClassOf obo:GO_0030534 . obo:NCBITaxon_2042557 a rdfs:Class ; rdfs:label "Coronavirus PREDICT CoV-32" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:PR_000017273 a rdfs:Class ; rdfs:label "transitional endoplasmic reticulum ATPase" ; rdfs:comment "A protein that is a translation product of the human VCP gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:PR_Q16832 a rdfs:Class ; rdfs:label "discoidin domain-containing receptor 2 (human)" ; rdfs:comment "A discoidin domain-containing receptor 2 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000001446 , obo:PR_000029067 . obo:HP_0007185 a rdfs:Class ; rdfs:label "Loss of consciousness" ; rdfs:subClassOf obo:HP_0004372 . obo:VO_0000498 a rdfs:Class ; rdfs:label "modification of adaptive immune response to antigen" ; rdfs:comment "modification of adaptive immune response to antigen is an active immunization process that results in modification of an adaptive immune response to some antigens, for example, in a therapeutic vaccine." ; rdfs:subClassOf obo:VO_0000491 . obo:CIDO_0000354 a rdfs:Class ; rdfs:label "angiotensin II receptor blocker role"@en ; rdfs:comment "A role taken by a chemical entity that binds to and inhibits the angiotensin II receptor type 1 (AT1) and thereby block the arteriolar contraction and sodium retention effects of renin–angiotensin system." ; rdfs:subClassOf obo:BFO_0000023 . obo:NCBITaxon_314295 a rdfs:Class ; rdfs:label "Hominoidea" ; rdfs:subClassOf obo:NCBITaxon_9526 . obo:CIDO_0000301 a rdfs:Class ; rdfs:label "SARS-CoV-2 epitope"@en ; rdfs:subClassOf obo:CIDO_0000300 . obo:OAE_0004525 a rdfs:Class ; rdfs:label "immediate post-injection reaction AE"@en ; rdfs:comment "an adverse event that occurs immediately after an injection" ; rdfs:subClassOf obo:OAE_0000366 . obo:OGG_3043740572 a rdfs:Class ; rdfs:label "ORF6 of severe acute respiratory syndrome coronavirus 2" ; rdfs:subClassOf obo:OGG_2002697049 . obo:UBERON_0001621 a rdfs:Class ; rdfs:label "coronary artery" ; rdfs:comment "An artery that supplies the myocardium." ; rdfs:subClassOf obo:UBERON_0000465 . obo:NCBITaxon_2509486 a rdfs:Class ; rdfs:label "Hibecovirus" ; rdfs:subClassOf obo:NCBITaxon_694002 . obo:GO_0043067 a rdfs:Class ; rdfs:label "regulation of programmed cell death" ; rdfs:comment "Any process that modulates the frequency, rate or extent of programmed cell death, cell death resulting from activation of endogenous cellular processes." ; rdfs:subClassOf obo:GO_0010941 . obo:CHEBI_26188 a rdfs:Class ; rdfs:label "polyketide" ; rdfs:comment "Natural compounds containing alternating carbonyl and methylene groups ('beta-polyketones'), biogenetically derived from repeated condensation of acetyl coenzyme A (via malonyl coenzyme A), and usually the compounds derived from them by further condensations. Considered by many to be synonymous with the less frequently used terms acetogenins and ketides." ; rdfs:subClassOf obo:CHEBI_17087 , obo:CHEBI_36963 . obo:CHEBI_29988 a rdfs:Class ; rdfs:label "L-glutamate(2-)" ; rdfs:comment "An L-alpha-amino acid anion that is the dianion obtained by the deprotonation of the both the carboxy groups of L-glutamic acid." ; rdfs:subClassOf obo:CHEBI_29987 , obo:CHEBI_59814 . obo:CIDO_0000621 a rdfs:Class ; rdfs:label "T9I in SARS-CoV-2 E protein" ; rdfs:comment "An AA mutation or AA variant that has mutated an amino acid at position 9 into a isoleucine" ; rdfs:subClassOf obo:CIDO_0000598 . a rdfs:Class ; rdfs:label "Atrial Flutter [Disease/Finding]" ; rdfs:subClassOf . obo:GO_0046942 a rdfs:Class ; rdfs:label "carboxylic acid transport" ; rdfs:comment "The directed movement of carboxylic acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Carboxylic acids are organic acids containing one or more carboxyl (COOH) groups or anions (COO-)." ; rdfs:subClassOf obo:GO_0015711 . obo:PR_000001168 a rdfs:Class ; rdfs:label "5-hydroxytryptamine receptor 2C" ; rdfs:comment "A 5-hydroxytryptamine receptor 2 that is a translation product of the human HTR2C gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000001099 . obo:PR_000008131 a rdfs:Class ; rdfs:label "golgin subfamily A member 2" ; rdfs:comment "A protein that is a translation product of the human GOLGA2 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:NCBITaxon_1788430 a rdfs:Class ; rdfs:label "Bat coronavirus RaBtCoV/4307-1" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:GO_0071219 a rdfs:Class ; rdfs:label "cellular response to molecule of bacterial origin" ; rdfs:comment "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus by molecules of bacterial origin such as peptides derived from bacterial flagellin." ; rdfs:subClassOf obo:GO_0002237 , obo:GO_0071216 . obo:CHEBI_57305 a rdfs:Class ; rdfs:label "glycine zwitterion" ; rdfs:comment "An amino acid zwitterion arising from transfer of a proton from the carboxy to the amino group of glycine." ; rdfs:subClassOf obo:CHEBI_35238 . obo:PR_000045383 a rdfs:Class ; rdfs:label "protein kinase C, iota-like" ; rdfs:comment "A protein that is a member of the phorbol ester (and diacylglycerol) receptor/protein kinase class. The canonical protein sequence has a core domain architecture consisting of a copy of the PB1 domain (Pfam:PF:00564), a Phorbol esters/diacylglycerol binding domain (C1 domain) (Pfam:PF00130), a Protein kinase domain (Pfam:PF00069) and a Protein kinase C terminal domain (Pfam:PF00433)." ; rdfs:subClassOf obo:PR_000000001 . obo:UBERON_0012168 a rdfs:Class ; rdfs:label "umbilical cord blood" ; rdfs:comment "blood that remains in the placenta and in the attached umbilical cord after childbirth[WP]." ; rdfs:subClassOf obo:UBERON_0000178 . obo:OBI_0000921 a rdfs:Class ; rdfs:label "labeled RNA extract" ; rdfs:comment "a labeled specimen that is the output of a labeling process and has grain labeled RNA to be able to detect RNA in future experiments." ; rdfs:subClassOf obo:OBI_0001143 . obo:GO_2000641 a rdfs:Class ; rdfs:label "regulation of early endosome to late endosome transport" ; rdfs:comment "Any process that modulates the frequency, rate or extent of early endosome to late endosome transport." ; rdfs:subClassOf obo:GO_0032386 , obo:GO_0060627 . obo:CIDO_0000296 a rdfs:Class ; rdfs:label "asymptomic human infected with pathogen"@en ; rdfs:comment "A human infected with pathogen that is asymptomtic for the disease process associated with the pathogen the human is infected with." ; rdfs:subClassOf obo:CIDO_0000290 . obo:GO_0007191 a rdfs:Class ; rdfs:label "adenylate cyclase-activating dopamine receptor signaling pathway" ; rdfs:comment "An adenylate cyclase-activating G protein-coupled receptor signaling pathway initiated by dopamine binding to its receptor, and ending with the regulation of a downstream cellular process." ; rdfs:subClassOf obo:GO_0007188 , obo:GO_0007212 . obo:HP_0012622 a rdfs:Class ; rdfs:label "Chronic kidney disease" ; rdfs:comment "Functional anomaly of the kidney persisting for at least three months." ; rdfs:subClassOf obo:HP_0000083 . a rdfs:Class ; rdfs:label "Cardiovascular Infections [Disease/Finding]" ; rdfs:subClassOf , . obo:VO_0005088 a rdfs:Class ; rdfs:label "EpiVacCorona"@en ; rdfs:comment "A SARS-CoV-2 protein subunit vaccine that relies on chemically synthesized peptide antigens of SARS-CoV-2 proteins, conjugated to a carrier protein and adsorbed on an aluminum-containing adjuvant (aluminum hydroxide)." ; rdfs:subClassOf obo:VO_0005269 . obo:NCBITaxon_550975 a rdfs:Class ; rdfs:label "Bat coronavirus M.aus/Australia/CoV132/2007" ; rdfs:subClassOf obo:NCBITaxon_366617 . obo:CIDO_0020018 a rdfs:Class ; rdfs:label "Alinity m SARS-CoV-2 assay" ; rdfs:seeAlso ; rdfs:subClassOf obo:CIDO_0000454 . obo:GO_0048015 a rdfs:Class ; rdfs:label "phosphatidylinositol-mediated signaling" ; rdfs:comment "The series of molecular signals in which a cell uses a phosphatidylinositol-mediated signaling to convert a signal into a response. Phosphatidylinositols include phosphatidylinositol (PtdIns) and its phosphorylated derivatives." ; rdfs:subClassOf obo:GO_0035556 . obo:HP_0012719 a rdfs:Class ; rdfs:label "Functional abnormality of the gastrointestinal tract" ; rdfs:comment "Abnormal functionality of the gastrointestinal tract." ; rdfs:subClassOf obo:HP_0011024 , obo:HP_0025032 . obo:CHEBI_79091 a rdfs:Class ; rdfs:label "EC 2.7.11.24 (mitogen-activated protein kinase) inhibitor" ; rdfs:comment "An EC 2.7.11.* (protein-serine/threonine kinase) inhibitor that interferes with the action of mitogen-activated protein kinase (EC 2.7.11.24)." ; rdfs:subClassOf obo:CHEBI_37699 , obo:CHEBI_76812 . obo:VO_0004679 a rdfs:Class ; rdfs:label "RBD-rAAV-SARS-CoV prime/RBD-specific T cell peptide boost" ; rdfs:subClassOf obo:VO_0012183 . obo:NCBITaxon_1788484 a rdfs:Class ; rdfs:label "Rhinolophus bat coronavirus BtCoV/3716" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:NCBITaxon_903596 a rdfs:Class ; rdfs:label "Kenya bat coronavirus BtKY58" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:PR_000006033 a rdfs:Class ; rdfs:label "cathepsin S" ; rdfs:comment "A cathepsin-like protease that is a translation product of the human CTSS gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000040662 . obo:CHEBI_24810 a rdfs:Class ; rdfs:label "indol-3-yl carboxylic acid" ; rdfs:comment "Any indolyl carboxylic acid carrying an indol-3-yl or substituted indol-3-yl group." ; rdfs:subClassOf obo:CHEBI_46867 . obo:UBERON_0000014 a rdfs:Class ; rdfs:label "zone of skin" ; rdfs:comment "Any portion of the organ that covers that body and consists of a layer of epidermis and a layer of dermis." ; rdfs:subClassOf obo:UBERON_0000064 , obo:UBERON_0004121 . obo:CHEBI_25697 a rdfs:Class ; rdfs:label "organic cation" ; rdfs:comment "Any organic ion with a net positive charge." ; rdfs:subClassOf obo:CHEBI_25699 , obo:CHEBI_36916 . obo:NCBITaxon_7776 a rdfs:Class ; rdfs:label "Gnathostomata " ; rdfs:subClassOf obo:NCBITaxon_7742 . obo:NCBITaxon_389149 a rdfs:Class ; rdfs:label "Bat coronavirus (BtCoV/A893/2005)" ; rdfs:subClassOf obo:NCBITaxon_389126 . obo:NCBITaxon_424364 a rdfs:Class ; rdfs:label "Bat coronavirus HKU5-2" ; rdfs:subClassOf obo:NCBITaxon_694008 . obo:NCBITaxon_681851 a rdfs:Class ; rdfs:label "Kenya bat coronavirus BtKY04" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:CHEBI_8212 a rdfs:Class ; rdfs:label "pimozide" ; rdfs:comment "A member of the class of benzimidazoles that is 1,3-dihydro-2H-benzimidazol-2-one in which one of the nitrogens is substituted by a piperidin-4-yl group, which in turn is substituted on the nitrogen by a 4,4-bis(p-fluorophenyl)butyl group." ; rdfs:subClassOf obo:CHEBI_22715 , obo:CHEBI_37143 , obo:CHEBI_48585 . obo:CHEBI_23367 a rdfs:Class ; rdfs:label "molecular entity" ; rdfs:comment "Any constitutionally or isotopically distinct atom, molecule, ion, ion pair, radical, radical ion, complex, conformer etc., identifiable as a separately distinguishable entity." ; rdfs:subClassOf obo:BFO_0000030 , obo:BFO_0000040 , obo:CHEBI_24431 . obo:CHEBI_142513 a rdfs:Class ; rdfs:label "oxime anion" ; rdfs:comment "A organic ion resulting from the deprotonation of the hydroxy group of any oxime." ; rdfs:subClassOf obo:CHEBI_25696 . obo:CHEBI_61697 a rdfs:Class ; rdfs:label "fatty acid derivative" ; rdfs:comment "Any organic molecular entity derived from a fatty acid." ; rdfs:subClassOf obo:CHEBI_18059 . obo:CHEBI_52092 a rdfs:Class ; rdfs:label "ethoxide" ; rdfs:comment "An organic anion that is the conjugate base of ethanol." ; rdfs:subClassOf obo:CHEBI_25696 . obo:NCBITaxon_239243 a rdfs:Class ; rdfs:label "SARS coronavirus CUHK-AG03" ; rdfs:subClassOf obo:NCBITaxon_694009 . obo:NCBITaxon_1699337 a rdfs:Class ; rdfs:label "Myotis Bat Alphacoronavirus strain YNXY_41C" ; rdfs:subClassOf obo:NCBITaxon_366617 . obo:BFO_0000028 a rdfs:Class ; rdfs:label "three-dimensional spatial region"@en ; rdfs:subClassOf obo:BFO_0000006 . obo:PR_000015243 a rdfs:Class ; rdfs:label "STE20-like serine/threonine-protein kinase" ; rdfs:comment "A protein that is a translation product of the human SLK gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:UBERON_0001557 a rdfs:Class ; rdfs:label "upper respiratory tract" ; rdfs:comment "The segment of the respiratory tract that starts proximally with the nose and ends distally with the cricoid cartilage, before continuing to the trachea." ; rdfs:subClassOf obo:UBERON_0000465 . a rdfs:Class ; rdfs:label "Organ System Specific Effects [PE]" ; rdfs:subClassOf . obo:CHEBI_73541 a rdfs:Class ; rdfs:label "organic heterobicyclic ring" ; rdfs:comment "A bicyclic organic group that contains both carbon and hetero atoms." ; rdfs:subClassOf obo:CHEBI_52845 . obo:HP_0011024 a rdfs:Class ; rdfs:label "Abnormality of the gastrointestinal tract" ; rdfs:comment "An abnormality of the gastrointestinal tract." ; rdfs:subClassOf obo:HP_0025031 . obo:CHEBI_35586 a rdfs:Class ; rdfs:label "1H-purine" ; rdfs:comment "The 1H-tautomer of purine." ; rdfs:subClassOf obo:CHEBI_35584 . obo:CIDO_0020228 a rdfs:Class ; rdfs:label "P23 Labs TaqPath SARS-CoV-2 Assay" ; rdfs:seeAlso ; rdfs:subClassOf obo:CIDO_0000454 . obo:PR_000002095 a rdfs:Class ; rdfs:label "sodium channel protein type 1 subunit alpha" ; rdfs:comment "A voltage-gated sodium channel subunit alpha that is a translation product of the human SCN1A gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000001975 . obo:PR_000029538 a rdfs:Class ; rdfs:label "HEAT repeat-containing protein 3" ; rdfs:comment "A protein that is a translation product of the human HEATR3 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:CIDO_0000892 a rdfs:Class ; rdfs:label "SARS-CoV2 nsp7 protein binding to human AGPS" ; rdfs:comment "SARS-CoV2 nsp7 protein binding to human AGPS, as evidented by an affinity-purification mass spectrometry experiment" ; rdfs:subClassOf obo:CIDO_0000049 . obo:NCBITaxon_633137 a rdfs:Class ; rdfs:label "SARS coronavirus MA15" ; rdfs:subClassOf obo:NCBITaxon_698398 . obo:CHEBI_189868 a rdfs:Class ; rdfs:label "Met-enkephalin zwitterion" ; rdfs:comment "A peptide zwitterion obtained by transfer of a proton from the carboxy to the amino terminus of Met-enkephalin. Major species at pH 7.3." ; rdfs:subClassOf obo:CHEBI_60466 . obo:PR_000014967 a rdfs:Class ; rdfs:label "synaptic vesicular amine transporter" ; rdfs:comment "A protein that is a translation product of the human SLC18A2 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:OAE_0000571 a rdfs:Class ; rdfs:label "abnormal respiration AE" ; rdfs:comment "a respiratory system AE which has an outcome of abnormal respiration, an anomaly in the movement of gases into and out of the lung"@en ; rdfs:subClassOf obo:OAE_0000378 . obo:CHEBI_33292 a rdfs:Class ; rdfs:label "fuel" ; rdfs:comment "An energy-rich substance that can be transformed with release of usable energy." ; rdfs:subClassOf obo:CHEBI_33232 . obo:PR_000030035 a rdfs:Class ; rdfs:label "G-protein coupled receptor" ; rdfs:comment "A protein that has G protein-coupled receptor (GPCR) activity. Each GPCR consists of a single polypeptide with an extracellular N-terminus, an intracellular C-terminus and seven hydrophobic transmembrane domains (TM1-TM7) linked by three extracellular loops (ECL1-ECL3) and three intracellular loops (ICL1-ICL3). GPCRs function as part of a heterotrimeric complex to transmit an extracellular signal across the membrane by activating an associated G-protein via the exchange of GDP for GTP on the alpha subunit." ; rdfs:subClassOf obo:PR_000000001 . obo:PR_Q6PHR2 a rdfs:Class ; rdfs:label "serine/threonine-protein kinase ULK3 (human)" ; rdfs:comment "A serine/threonine-protein kinase ULK3 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000017079 , obo:PR_000029067 . obo:CIDO_0020281 a rdfs:Class ; rdfs:label "SARS-CoV-2 RT-PCR test Infectious Disease Diagnostics Laboratory - Children's Hospital of Philadelphia" ; rdfs:seeAlso ; rdfs:subClassOf obo:CIDO_0000454 . obo:PR_000009852 a rdfs:Class ; rdfs:label "vesicular integral-membrane protein VIP36" ; rdfs:comment "A protein that is a translation product of the human LMAN2 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:VO_0005258 a rdfs:Class ; rdfs:label "MF59-adjuvanted SARS-CoV-2 Sclamp vaccine"@en ; rdfs:comment "An MF59-adjuvanted SARS-CoV-2 subunit vaccine based on recombinant SARS-CoV-2 spike glycoprotein stabilised in a pre-fusion conformation by a novel molecular clamp (spike glycoprotein-clamp [sclamp])" ; rdfs:subClassOf obo:VO_0005202 . obo:HP_0006699 a rdfs:Class ; rdfs:label "Premature atrial contractions" ; rdfs:comment "A type of cardiac arrhythmia with premature atrial contractions or beats caused by signals originating from ectopic atrial sites." ; rdfs:subClassOf obo:HP_0005115 . obo:OBI_0000915 a rdfs:Class ; rdfs:label "freezing storage" ; rdfs:comment "A storage process in temperature that maintenance the frozen status of the stored entities." ; rdfs:subClassOf obo:OBI_0302893 . obo:PR_000012239 a rdfs:Class ; rdfs:label "serine/threonine-protein kinase PAK 1" ; rdfs:comment "A protein that is a translation product of the human PAK1 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:NCBITaxon_622711 a rdfs:Class ; rdfs:label "Bat coronavirus Hipposideros/GhanaKwam/19/2008" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:PR_000012911 a rdfs:Class ; rdfs:label "mitochondrial-processing peptidase subunit alpha" ; rdfs:comment "A protein that is a translation product of the human PMPCA gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:OBI_2000012 a rdfs:Class ; rdfs:label "umbilical cord blood specimen" ; rdfs:comment "A specimen that is derived from some umbilical cord blood" ; rdfs:subClassOf obo:OBI_2000009 . obo:CIDO_0000751 a rdfs:Class ; rdfs:label "SARS-CoV2 M protein binding to human ATP1B1" ; rdfs:comment "SARS-CoV2 M protein binding to human ATP1B1, as evidented by an affinity-purification mass spectrometry experiment" ; rdfs:subClassOf obo:CIDO_0000055 . a rdfs:Class ; rdfs:label "Ketones [Chemical/Ingredient]" ; rdfs:subClassOf . obo:GO_0071222 a rdfs:Class ; rdfs:label "cellular response to lipopolysaccharide" ; rdfs:comment "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lipopolysaccharide stimulus; lipopolysaccharide is a major component of the cell wall of gram-negative bacteria." ; rdfs:subClassOf obo:GO_0032496 , obo:GO_0071219 , obo:GO_0071396 , obo:GO_1901701 . obo:CIDO_0000253 a rdfs:Class ; rdfs:label "nsp5_C145A"@en ; rdfs:comment "A catalytically dead Nsp5 (C145A) with tRNA methyltransferase 1 (TRMT1), which is responsible for the dimethylation of guanosine (m2,2G) on both nuclear and mitochondrial tRNAs (Ref: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7431030/)." ; rdfs:subClassOf obo:PR_000050274 . obo:CHEBI_35477 a rdfs:Class ; rdfs:label "antimanic drug" ; rdfs:comment "Antimanic drugs are agents used to treat bipolar disorders or mania associated with other affective disorders." ; rdfs:subClassOf obo:CHEBI_35473 . obo:OBI_0000079 a rdfs:Class ; rdfs:label "culture medium"@en ; rdfs:comment "a processed material that provides the needed nourishment for microorganisms or cells grown in vitro." ; rdfs:subClassOf obo:OBI_0000047 . a rdfs:Class ; rdfs:label "Endocarditis [Disease/Finding]" ; rdfs:subClassOf . obo:NCBITaxon_702701 a rdfs:Class ; rdfs:label "Bovine coronavirus Bubalus/82/ITA/2008" ; rdfs:subClassOf obo:NCBITaxon_11128 . obo:PR_000005586 a rdfs:Class ; rdfs:label "dual specificity protein kinase CLK3" ; rdfs:comment "A protein that is a translation product of the human CLK3 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:NCBITaxon_1788470 a rdfs:Class ; rdfs:label "Miniopterus bat coronavirus BtCoV/3983" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:VO_0001301 a rdfs:Class ; rdfs:label "MF59 vaccine adjuvant" ; rdfs:comment "An emulsion vaccine adjuvant consisting of an oil (squalene)-in-water nano emulsion." ; rdfs:subClassOf obo:VO_0001355 . obo:CHEBI_59558 a rdfs:Class ; rdfs:label "medium-chain fatty acid anion" ; rdfs:comment "A fatty acid anion resulting from the deprotonation of the carboxylic acid moiety of a medium-chain fatty acid." ; rdfs:subClassOf obo:CHEBI_28868 . obo:CIDO_0000635 a rdfs:Class ; rdfs:label "G3676- in SARS-CoV-2 pp1a protein" ; rdfs:comment "An AA mutation or AA variant that has mutated an amino acid at position 3676 into a deletion" ; rdfs:subClassOf obo:CIDO_0001149 . obo:CHEBI_16136 a rdfs:Class ; rdfs:label "hydrogen sulfide" ; rdfs:comment "A sulfur hydride consisting of a single sulfur atom bonded to two hydrogen atoms. A highly poisonous, flammable gas with a characteristic odour of rotten eggs, it is often produced by bacterial decomposition of organic matter in the absence of oxygen." ; rdfs:subClassOf obo:CHEBI_138675 , obo:CHEBI_33405 , obo:CHEBI_33535 , obo:CHEBI_37176 . obo:CHEBI_24828 a rdfs:Class ; rdfs:label "indoles" ; rdfs:comment "Any compound containing an indole skeleton." ; rdfs:subClassOf obo:CHEBI_22728 . obo:NCBITaxon_2611352 a rdfs:Class ; rdfs:label "Discoba" ; rdfs:subClassOf obo:NCBITaxon_2759 . a rdfs:Class ; rdfs:label "Adenovirus Infections, Human [Disease/Finding]" ; rdfs:subClassOf . obo:CIDO_0020029 a rdfs:Class ; rdfs:label "AQ-TOP COVID-19 Rapid Detection Kit PLUS" ; rdfs:seeAlso ; rdfs:subClassOf obo:CIDO_0000454 . obo:CIDO_0000505 a rdfs:Class ; rdfs:label "LIPRSYYLIQSGIFF" ; rdfs:comment "A coronavirus epitope that is part of some S protein from HCoV HKU1 composed of the following amino acids LIPRSYYLIQSGIFF" ; rdfs:subClassOf obo:CIDO_0000450 . a rdfs:Class ; rdfs:label "Serotonin Receptor Interactions [MoA]" ; rdfs:subClassOf . obo:APOLLO_SV_00000322 a rdfs:Class ; rdfs:label "voluntary household quarantine control strategy"@en ; rdfs:comment "An infectious disease control strategy whereby the household members of infectious indivduals voluntarily stay at home to avoid further potentially infectious contacts."@en ; rdfs:subClassOf obo:APOLLO_SV_00000086 . obo:UBERON_0013757 a rdfs:Class ; rdfs:label "capillary blood" ; rdfs:comment "A blood that is part of a capillary." ; rdfs:subClassOf obo:UBERON_0000178 . a rdfs:Class ; rdfs:label "Neoplasms, Vascular Tissue [Disease/Finding]" ; rdfs:subClassOf . obo:NCBITaxon_1477411 a rdfs:Class ; rdfs:label "Deltacoronavirus PDCoV/USA/Illinois133/2014" ; rdfs:subClassOf obo:NCBITaxon_1159905 . obo:CHEBI_3649 a rdfs:Class ; rdfs:label "chlorpromazine hydrochloride" ; rdfs:comment "The hydrochloride salt of chlorpromazine." ; rdfs:subClassOf obo:CHEBI_36807 , obo:CHEBI_38093 . obo:NCBITaxon_1892416 a rdfs:Class ; rdfs:label "Rousettus bat coronavirus" ; rdfs:subClassOf obo:NCBITaxon_2501962 . obo:CIDO_0000708 a rdfs:Class ; rdfs:label "SARS-CoV-2 induced syncytia formation"@en ; rdfs:subClassOf obo:CIDO_0000197 . obo:NCBITaxon_267387 a rdfs:Class ; rdfs:label "SARS coronavirus Sin848" ; rdfs:subClassOf obo:NCBITaxon_694009 . obo:SYMP_0000462 a rdfs:Class ; rdfs:subClassOf obo:BFO_0000019 . obo:CIDO_0000804 a rdfs:Class ; rdfs:label "SARS-CoV2 nsp12 protein binding to human BCKDK" ; rdfs:comment "SARS-CoV2 nsp12 protein binding to human BCKDK, as evidented by an affinity-purification mass spectrometry experiment" ; rdfs:subClassOf obo:CIDO_0000057 . obo:CHEBI_26606 a rdfs:Class ; rdfs:label "sapogenin" ; rdfs:comment "Any organic polycyclic compound that is the aglycon moiety of a saponin; sapogenins may be steroids or triterpenoids." ; rdfs:subClassOf obo:CHEBI_51958 . obo:PR_O14757 a rdfs:Class ; rdfs:label "serine/threonine-protein kinase Chk1 (human)" ; rdfs:comment "A serine/threonine-protein kinase Chk1 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000005417 , obo:PR_000029067 . obo:VO_0005240 a rdfs:Class ; rdfs:label "MV-014-212"@en ; rdfs:comment "A SARS-CoV-2 live, attenuated vaccine manufactured by Meissa Vaccines, Inc. that expresses the spike (S) protein of SARS-CoV-2." ; rdfs:subClassOf obo:VO_0005204 . obo:CIDO_0000632 a rdfs:Class ; rdfs:label "T205I in SARS-CoV-2 N protein" ; rdfs:comment "An AA mutation or AA variant that has mutated an amino acid at position 205 into a isoleucine in N protein." ; rdfs:subClassOf obo:CIDO_0000596 . obo:DOID_0060048 a rdfs:Class ; rdfs:label "nosophobia" ; rdfs:comment "A specific phobia that involves an irrational fear of contracting a disease." ; rdfs:subClassOf obo:DOID_599 . obo:GO_0006612 a rdfs:Class ; rdfs:label "protein targeting to membrane" ; rdfs:comment "The process of directing proteins towards a membrane, usually using signals contained within the protein." ; rdfs:subClassOf obo:GO_0006605 , obo:GO_0090150 . obo:PR_Q9Y2U5 a rdfs:Class ; rdfs:label "mitogen-activated protein kinase kinase kinase 2 (human)" ; rdfs:comment "A mitogen-activated protein kinase kinase kinase 2 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000010135 , obo:PR_000029067 . obo:CIDO_0020330 a rdfs:Class ; rdfs:label "VITROS Immunodiagnostic Products SARS-CoV-2 Antigen Reagent Pack" ; rdfs:seeAlso ; rdfs:subClassOf obo:CIDO_0000454 . obo:CHEBI_46867 a rdfs:Class ; rdfs:label "indolyl carboxylic acid" ; rdfs:subClassOf obo:CHEBI_24828 , obo:CHEBI_33575 . obo:CIDO_0020096 a rdfs:Class ; rdfs:label "COVID-19 Nucleic Acid RT-PCR Test Kit" ; rdfs:seeAlso ; rdfs:subClassOf obo:CIDO_0000454 . obo:PR_Q13557 a rdfs:Class ; rdfs:label "calcium/calmodulin-dependent protein kinase type II subunit delta (human)" ; rdfs:comment "A calcium/calmodulin-dependent protein kinase type II subunit delta that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000003201 , obo:PR_000029067 . obo:CHEBI_64898 a rdfs:Class ; rdfs:label "anionic amino-acid residue" ; rdfs:comment "An amino-acid residue carrying an overall negative charge." ; rdfs:subClassOf obo:CHEBI_64775 . obo:NCBITaxon_1263720 a rdfs:Class ; rdfs:label "Betacoronavirus England 1" ; rdfs:subClassOf obo:NCBITaxon_1335626 . obo:CHEBI_50925 a rdfs:Class ; rdfs:label "EC 2.7.11.1 (non-specific serine/threonine protein kinase) inhibitor" ; rdfs:comment "An EC 2.7.11.* (protein-serine/threonine kinase) inhibitor that interferes with the action of non-specific serine/threonine protein kinase (EC 2.7.11.1), a kinase enzyme involved in phosphorylation of hydroxy group of serine or threonine." ; rdfs:subClassOf obo:CHEBI_76812 . obo:VO_0005318 a rdfs:Class ; rdfs:label "CVXGA1"@en ; rdfs:comment "A SARS-CoV-2 recombinant vector vaccine manufactured by CyanVac LLC" ; rdfs:subClassOf obo:VO_0005200 . obo:CHEBI_28487 a rdfs:Class ; rdfs:label "reserpine" ; rdfs:comment "An alkaloid found in the roots of Rauwolfia serpentina and R. vomitoria." ; rdfs:subClassOf obo:CHEBI_25248 , obo:CHEBI_27358 , obo:CHEBI_38481 . a rdfs:Class ; rdfs:label "Leukocyte Disorders [Disease/Finding]" ; rdfs:subClassOf . obo:NCBITaxon_1788495 a rdfs:Class ; rdfs:label "Rhinolophus bat coronavirus BtCoV/4307-1" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:CIDO_0000293 a rdfs:Class ; rdfs:label "human female infected by SARS-CoV-2"@en ; rdfs:subClassOf obo:CIDO_0000292 . obo:PR_O75469 a rdfs:Class ; rdfs:label "nuclear receptor subfamily 1 group I member 2 (human)" ; rdfs:comment "A nuclear receptor subfamily 1 group I member 2 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000011397 , obo:PR_000029067 . obo:PR_000008886 a rdfs:Class ; rdfs:label "insulin-degrading enzyme" ; rdfs:comment "A protein that is a translation product of the human IDE gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:NCBITaxon_2795397 a rdfs:Class ; rdfs:label "Minacovirus mink/NLD/2020/NT_4" ; rdfs:subClassOf obo:NCBITaxon_2727857 . obo:CHEBI_33893 a rdfs:Class ; rdfs:label "reagent" ; rdfs:comment "A substance used in a chemical reaction to detect, measure, examine, or produce other substances." ; rdfs:subClassOf obo:CHEBI_33232 . obo:OBI_2000003 a rdfs:Class ; rdfs:label "throat specimen" ; rdfs:comment "A specimen that is derived from some throat " ; rdfs:subClassOf obo:OBI_0001479 . obo:CHEBI_35748 a rdfs:Class ; rdfs:label "fatty acid ester" ; rdfs:comment "A carboxylic ester in which the carboxylic acid component can be any fatty acid." ; rdfs:subClassOf obo:CHEBI_33308 , obo:CHEBI_61697 . obo:GO_0003086 a rdfs:Class ; rdfs:label "regulation of systemic arterial blood pressure by local renal renin-angiotensin" ; rdfs:comment "The process in which angiotensinogen metabolites in the kidney modulate the force with which blood passes through the renal circulatory system. The process begins when renin cleaves angiotensinogen." ; rdfs:subClassOf obo:GO_0003081 . obo:DOID_0070079 a rdfs:Class ; rdfs:label "schizophrenia 3" ; rdfs:comment "A schizophrenia that has_material_basis_in an autosomal dominant mutation of SCZD3 on chromosome 6p23." ; rdfs:subClassOf obo:DOID_0050736 , obo:DOID_5419 . obo:PR_000050264 a rdfs:Class ; rdfs:label "ORF8 protein, signal peptide removed form (SARS-CoV-2)" ; rdfs:comment "An ORF8 protein (SARS-CoV-2) that has had the signal peptide removed. UniProtKB:P0DTC8, 16-121." ; rdfs:subClassOf obo:PR_P0DTC8 . obo:VO_0005333 a rdfs:Class ; rdfs:label "SII B.1.351"@en ; rdfs:comment "A SARS-CoV-2 monovalent protein subunit vaccine by Novavax immunizing against the B.1.351 (Beta) variant and containing the Matrix-M1 adjuvant" ; rdfs:subClassOf obo:VO_0005202 . obo:CHEBI_27092 a rdfs:Class ; rdfs:label "tricarboxylic acid trianion" ; rdfs:subClassOf obo:CHEBI_35753 , obo:CHEBI_38717 . obo:CHEBI_167183 a rdfs:Class ; rdfs:label "piscicide" ; rdfs:comment "A substance which is poisonous to fish and is primarily used to eliminate dominant species of fish in water." ; rdfs:subClassOf obo:CHEBI_25944 . obo:NCBITaxon_1881087 a rdfs:Class ; rdfs:label "Kerivoula titania coronavirus" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:NCBITaxon_1415849 a rdfs:Class ; rdfs:label "Bat SARS-like coronavirus Rs4108" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:NCBITaxon_903607 a rdfs:Class ; rdfs:label "Kenya bat coronavirus BtKY69" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:CHEBI_33302 a rdfs:Class ; rdfs:label "pnictogen molecular entity" ; rdfs:comment "A p-block molecular entity containing any pnictogen." ; rdfs:subClassOf obo:CHEBI_33675 . obo:NCBITaxon_2020507 a rdfs:Class ; rdfs:label "Myotis lucifugus coronavirus" ; rdfs:subClassOf obo:NCBITaxon_1913643 . obo:OBI_0002127 a rdfs:Class ; rdfs:label "single cell specimen"@en ; rdfs:comment "A cell specimen that contains only one cell." ; rdfs:subClassOf obo:OBI_0001468 . obo:CHEBI_25585 a rdfs:Class ; rdfs:label "nonmetal atom" ; rdfs:subClassOf obo:CHEBI_33250 . obo:OBI_0002782 a rdfs:Class ; rdfs:label "upper respiratory specimen" ; rdfs:comment "A specimen that is derived from the upper respiratory tract" ; rdfs:subClassOf obo:OBI_0002599 . obo:CHEBI_36830 a rdfs:Class ; rdfs:label "monoanion" ; rdfs:subClassOf obo:CHEBI_22563 . obo:PR_000007160 a rdfs:Class ; rdfs:label "receptor tyrosine-protein kinase erbB-4" ; rdfs:comment "An EGF receptor type tyrosine-protein kinase that is a translation product of the human ERBB4 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000001812 . obo:CHEBI_37670 a rdfs:Class ; rdfs:label "protease inhibitor" ; rdfs:comment "A compound which inhibits or antagonizes the biosynthesis or actions of proteases (endopeptidases)." ; rdfs:subClassOf obo:CHEBI_60258 . obo:NCBITaxon_681854 a rdfs:Class ; rdfs:label "Kenya bat coronavirus BtKY07" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:PR_Q5T6F2 a rdfs:Class ; rdfs:label "ubiquitin-associated protein 2 (human)" ; rdfs:comment "A ubiquitin-associated protein 2 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000016959 , obo:PR_000029067 . obo:PR_000044676 a rdfs:Class ; rdfs:label "channel protein" ; rdfs:comment "A protein that has channel activity. Channel proteins enable energy-independent facilitated diffusion, mediated by passage of a solute through a transmembrane aqueous pore or channel." ; rdfs:subClassOf obo:PR_000000001 . obo:CHEBI_58095 a rdfs:Class ; rdfs:label "L-phenylalanine zwitterion" ; rdfs:comment "An amino acid zwitterion arising from transfer of a proton from the carboxy to the amino group of L-phenylalanine; major species at pH 7.3." ; rdfs:subClassOf obo:CHEBI_35238 . obo:CHEBI_145372 a rdfs:Class ; rdfs:label "gilteritinib" ; rdfs:comment "A member of the class of pyrazines that is pyrazine-2-carboxamide which is substituted by {3-methoxy-4-[4-(4-methylpiperazin-1-yl)piperidin-1-yl]phenyl}nitrilo, (oxan-4-yl)nitrilo and ethyl groups at positions 3,5 and 6, respectively. It is a potent inhibitor of FLT3 and AXL tyrosine kinase receptors (IC50 = 0.29 nM and 0.73 nM, respectively). Approved by the FDA for the treatment of acute myeloid leukemia in patients who have a FLT3 gene mutation." ; rdfs:subClassOf obo:CHEBI_140324 , obo:CHEBI_25235 , obo:CHEBI_26151 , obo:CHEBI_33860 , obo:CHEBI_38314 , obo:CHEBI_46920 , obo:CHEBI_46942 , obo:CHEBI_50995 . obo:NCBITaxon_2042577 a rdfs:Class ; rdfs:label "Coronavirus PREDICT CoV-53" ; rdfs:subClassOf obo:NCBITaxon_366617 . obo:NCBITaxon_267394 a rdfs:Class ; rdfs:label "SARS coronavirus SinP5" ; rdfs:subClassOf obo:NCBITaxon_694009 . obo:NCBITaxon_366619 a rdfs:Class ; rdfs:label "Ferret enteric coronavirus MSU1" ; rdfs:subClassOf obo:NCBITaxon_366617 . obo:PR_000003199 a rdfs:Class ; rdfs:label "calcium/calmodulin-dependent protein kinase type II subunit alpha" ; rdfs:comment "A calcium/calmodulin-dependent protein kinase type II chain that is a translation product of the human CAMK2A gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000003197 . obo:GO_0050790 a rdfs:Class ; rdfs:label "regulation of catalytic activity" ; rdfs:comment "Any process that modulates the activity of an enzyme." ; rdfs:subClassOf obo:GO_0065009 . a rdfs:Class ; rdfs:label "Infant [Disease/Finding]" ; rdfs:subClassOf . obo:PR_Q15208 a rdfs:Class ; rdfs:label "serine/threonine-protein kinase 38 (human)" ; rdfs:comment "A serine/threonine-protein kinase 38 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000015754 , obo:PR_000029067 . obo:CIDO_0000762 a rdfs:Class ; rdfs:label "SARS-CoV2 M protein binding to human PMPCB" ; rdfs:comment "SARS-CoV2 M protein binding to human PMPCB, as evidented by an affinity-purification mass spectrometry experiment" ; rdfs:subClassOf obo:CIDO_0000055 . obo:CMO_0000000 a rdfs:Class ; rdfs:label "clinical measurement" ; rdfs:subClassOf obo:IAO_0000109 . obo:CHEBI_36684 a rdfs:Class ; rdfs:label "organohalogen compound" ; rdfs:comment "A compound containing at least one carbon-halogen bond." ; rdfs:subClassOf obo:CHEBI_33285 , obo:CHEBI_37578 . obo:OBI_0002691 a rdfs:Class ; rdfs:label "arthropod meal of blood specimen" ; rdfs:comment "A specimen of the blood ingested by an arthropod." ; rdfs:subClassOf obo:OBI_0100051 . obo:HP_0011694 a rdfs:Class ; rdfs:label "Supraventricular tachycardia with a manifest accessory pathway" ; rdfs:subClassOf obo:HP_0011688 . obo:GO_0048518 a rdfs:Class ; rdfs:label "positive regulation of biological process" ; rdfs:comment "Any process that activates or increases the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule." ; rdfs:subClassOf obo:GO_0050789 . obo:DRON_00012403 a rdfs:Class ; rdfs:label "Amodiaquine" ; rdfs:subClassOf obo:OBI_0000047 . obo:CIDO_0001224 a rdfs:Class ; rdfs:label "SARS-CoV-2 Nucleic Acid Detection Kit (isothermal amplification-real-time fluorescence method) (Ustar Biotechnologies (Hangzhou) Ltd.)" ; rdfs:comment "Manufacturor: Ustar Biotechnologies (Hangzhou) Ltd. 杭州优思达生物技术有限公司" ; rdfs:subClassOf obo:CIDO_0000021 . obo:CHEBI_59999 a rdfs:Class ; rdfs:label "chemical substance" ; rdfs:comment "A chemical substance is a portion of matter of constant composition, composed of molecular entities of the same type or of different types." ; rdfs:subClassOf obo:BFO_0000030 , obo:CHEBI_24431 . obo:NCBITaxon_2042540 a rdfs:Class ; rdfs:label "Coronavirus PREDICT CoV-13" ; rdfs:subClassOf obo:NCBITaxon_366617 . obo:PR_Q96I59 a rdfs:Class ; rdfs:label "probable asparagine--tRNA ligase, mitochondrial (human)" ; rdfs:comment "An asparagine--tRNA ligase, mitochondrial that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000029067 , obo:PR_000030931 . obo:CHEBI_34073 a rdfs:Class ; rdfs:label "Delta(1)-progesterone" ; rdfs:comment "A 3-oxo Delta(4)-steroid that is progesterone which has been oxidised to introduce a double bond between positions 1 and 2." ; rdfs:subClassOf obo:CHEBI_36885 , obo:CHEBI_77166 . obo:OBI_0000378 a rdfs:Class ; rdfs:label "filter function"@en ; rdfs:comment "A filter function is a function to prevent the flow of certain entities based on a quality or qualities of the entity while allowing entities which have different qualities to pass through"@en ; rdfs:subClassOf obo:OBI_0000372 . obo:PR_000050059 a rdfs:Class ; rdfs:label "doublecortin-like kinase" ; rdfs:comment "A protein that is a translation product of the human DCLK1, DCLK2, or DCLK3 genes, 1:1 orthologs thereof, or a semi-ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:OMRSE_00000095 a rdfs:Class ; rdfs:label "payer role"@en ; rdfs:subClassOf obo:OMRSE_00000024 . obo:PR_000012590 a rdfs:Class ; rdfs:label "cyclin-dependent kinase 15" ; rdfs:comment "A CDK2-related kinase that is a translation product of the human CDK15 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000003270 . obo:CHEBI_24839 a rdfs:Class ; rdfs:label "inorganic salt" ; rdfs:subClassOf obo:CHEBI_24835 , obo:CHEBI_24866 . obo:PR_000009817 a rdfs:Class ; rdfs:label "LIM domain kinase 2" ; rdfs:comment "A protein that is a translation product of the human LIMK2 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:GO_0051481 a rdfs:Class ; rdfs:label "negative regulation of cytosolic calcium ion concentration" ; rdfs:comment "Any process that decreases the concentration of calcium ions in the cytosol." ; rdfs:subClassOf obo:GO_0065008 . obo:CIDO_0000446 a rdfs:Class ; rdfs:label "spike glycoprotein (HCoV NL63)"@en ; rdfs:comment "A surface glycoprotein of human coronavirus NL63." ; rdfs:subClassOf obo:CIDO_0000442 . obo:CIDO_0020142 a rdfs:Class ; rdfs:label "Fosun COVID-19 RT-PCR Detection Kit" ; rdfs:seeAlso ; rdfs:subClassOf obo:CIDO_0000454 . obo:PR_000003003 a rdfs:Class ; rdfs:label "tyrosine-protein kinase Fyn" ; rdfs:comment "A proto-oncogene SRC-like tyrosine-protein kinase that is a translation product of the human FYN gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000002997 . obo:CIDO_0000907 a rdfs:Class ; rdfs:label "SARS-CoV2 nsp7 protein binding to human PTGES2" ; rdfs:comment "SARS-CoV2 nsp7 protein binding to human PTGES2, as evidented by an affinity-purification mass spectrometry experiment" ; rdfs:subClassOf obo:CIDO_0000049 . a rdfs:Class ; rdfs:label "Rimantadine [Chemical/Ingredient]" ; rdfs:subClassOf . obo:PR_P35367 a rdfs:Class ; rdfs:label "histamine H1 receptor (human)" ; rdfs:comment "A histamine H1 receptor that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000001422 , obo:PR_000029067 . obo:CHEBI_131327 a rdfs:Class ; rdfs:label "amodiaquine(1+)" ; rdfs:comment "An organic cation obtained by protonation of the tertiary amino group of amodiaquine; major species at pH 7.3." ; rdfs:subClassOf obo:CHEBI_25697 , obo:CHEBI_35274 . a rdfs:Class ; rdfs:label "Vertigo [Disease/Finding]" ; rdfs:subClassOf , . obo:OAE_0000317 a rdfs:Class ; rdfs:label "hypoesthesia AE" ; rdfs:comment "a sensory capability AE that has an outcome of hypoaesthesia, meaning that skin loses some of its sensitivity to pain or touch" ; rdfs:subClassOf obo:OAE_0000582 . obo:PR_000012958 a rdfs:Class ; rdfs:label "GDP-fucose protein O-fucosyltransferase 1" ; rdfs:comment "A protein that is a translation product of the human POFUT1 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . a rdfs:Class ; rdfs:label "Leukemia, Hairy Cell [Disease/Finding]" ; rdfs:subClassOf , . a rdfs:Class ; rdfs:label "Coccidiosis [Disease/Finding]" ; rdfs:subClassOf . obo:CIDO_0000725 a rdfs:Class ; rdfs:label "L3201P in SARS-CoV-2 pp1a protein"@en ; rdfs:comment "An AA mutation or AA variant that has mutated an amino acid at position 3201 into a leucine in pp1a." ; rdfs:subClassOf obo:CIDO_0001075 . a rdfs:Class ; rdfs:label "RIBAVIRIN" ; rdfs:subClassOf . obo:CIDO_0000791 a rdfs:Class ; rdfs:label "SARS-CoV2 nsp1 protein binding to human COLGALT1" ; rdfs:comment "SARS-CoV2 nsp1 protein binding to human COLGALT1, as evidented by an affinity-purification mass spectrometry experiment" ; rdfs:subClassOf obo:CIDO_0000062 . a rdfs:Class ; rdfs:label "EMETINE" ; rdfs:subClassOf . obo:PR_000004517 a rdfs:Class ; rdfs:label "aurora kinase B" ; rdfs:comment "An aurora kinase that is a translation product of the human AURKB gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000035365 . obo:DRON_00000026 a rdfs:Class ; rdfs:label "drug capsule"@en ; rdfs:comment "an object that is the bearer of a drug role and is comprised of a solid shell of elliptical-cylindrical shape and another object contained in the shell that has a scattered molecular aggregate as a proper part"@en ; rdfs:subClassOf obo:BFO_0000030 . a rdfs:Class ; rdfs:label "Valinomycin [Chemical/Ingredient]" ; rdfs:subClassOf . obo:CHEBI_35274 a rdfs:Class ; rdfs:label "ammonium ion derivative" ; rdfs:comment "A derivative of ammonium, NH4(+), in which one (or more) of the hydrogens bonded to the nitrogen have been replaced with univalent organyl groups. The substituting carbon of the organyl group must not itself be directly attached to a heteroatom (thereby excluding protonated amides, hemiaminals, etc)." ; rdfs:subClassOf obo:CHEBI_33702 , obo:CHEBI_51143 . obo:CHEBI_46845 a rdfs:Class ; rdfs:label "N-alkylpiperazine" ; rdfs:subClassOf obo:CHEBI_26144 , obo:CHEBI_50996 . obo:PR_000044652 a rdfs:Class ; rdfs:label "inwardly rectifying potassium channel protein" ; rdfs:comment "A potassium channel protein that has inward rectifier potassium channel activity. An inwardly rectifying potassium channel is one where the inward flow of K+ ions exceeds the outward flow." ; rdfs:subClassOf obo:PR_000044655 . obo:PR_000001614 a rdfs:Class ; rdfs:label "muscarinic acetylcholine receptor M2" ; rdfs:comment "A muscarinic acetylcholine receptor that is a translation product of the human CHRM2 gene or a 1:1 ortholog thereof. This receptor is expressed in cardiac tissues and acts to slow the heart rate to normal after sympathetic nervous system stimulation." ; rdfs:subClassOf obo:PR_000001488 . obo:CHEBI_50857 a rdfs:Class ; rdfs:label "anti-allergic agent" ; rdfs:comment "A drug used to treat allergic reactions." ; rdfs:subClassOf obo:CHEBI_23888 . obo:DRON_00019979 a rdfs:Class ; rdfs:label "fingolimod" ; rdfs:subClassOf obo:OBI_0000047 . obo:CHEBI_35496 a rdfs:Class ; rdfs:label "fluorobenzenes" ; rdfs:comment "Any fluoroarene that is a benzene or a substituted benzene carrying at least one fluoro group." ; rdfs:subClassOf obo:CHEBI_22712 , obo:CHEBI_37143 . obo:PR_000000037 a rdfs:Class ; rdfs:label "BMP receptor type-2" ; rdfs:comment "A TGF-beta superfamily receptor type-2 with activin receptor domain that is a translation product of the human BMPR2 gene or a 1:1 ortholog thereof. Bone morphogenetic protein (BMP) signals are transmitted by type 2 and type 1 serine/threonine kinase receptors. Type 2 receptors phosphorylate and activate type 1 receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators." ; rdfs:subClassOf obo:PR_000000007 . obo:CHEBI_76870 a rdfs:Class ; rdfs:label "EC 1.9.3.* (oxidoreductase acting on donor heme group, oxygen as acceptor) inhibitor" ; rdfs:comment "An EC 1.9.* (oxidoreductase acting on donor heme group) inhibitor that interferes with the action of any such enzyme using oxygen as acceptor (EC 1.9.3.*)." ; rdfs:subClassOf obo:CHEBI_76736 . obo:CHEBI_35779 a rdfs:Class ; rdfs:label "dicarboxylic acid diamide" ; rdfs:subClassOf obo:CHEBI_23690 . obo:PR_000049983 a rdfs:Class ; rdfs:label "ion channel protein" ; rdfs:comment "A channel protein that has ion channel activity. An ion channel enables the facilitated diffusion of an ion (by an energy-independent process) by passage through a transmembrane aqueous pore or channel without evidence for a carrier-mediated mechanism." ; rdfs:subClassOf obo:PR_000044676 . a rdfs:Class ; rdfs:label "Heterocyclic Compounds, 2-Ring [Chemical/Ingredient]" ; rdfs:subClassOf . obo:NCBITaxon_305412 a rdfs:Class ; rdfs:label "SARS coronavirus C014" ; rdfs:subClassOf obo:NCBITaxon_694009 . obo:CHEBI_59561 a rdfs:Class ; rdfs:label "diamino acid anion" ; rdfs:comment "An organic anion that is the conjugate base of diamino acid." ; rdfs:subClassOf obo:CHEBI_25696 . a rdfs:Class ; rdfs:label "Protozoan Infections, Animal [Disease/Finding]" ; rdfs:subClassOf , . obo:CHEBI_33598 a rdfs:Class ; rdfs:label "carbocyclic compound" ; rdfs:comment "A homocyclic compound in which all of the ring members are carbon atoms." ; rdfs:subClassOf obo:CHEBI_33597 , obo:CHEBI_33832 . obo:CIDO_0000112 a rdfs:Class ; rdfs:label "modulation of host response to SARS-CoV-2 infection"@en ; rdfs:comment "A process that modulates host response to SARS-CoV-2 viral infection" ; rdfs:subClassOf obo:CIDO_0000111 . obo:CIDO_0000650 a rdfs:Class ; rdfs:label "S26L in SARS-CoV-2 NS3 protein" ; rdfs:comment "An AA mutation or AA variant that has mutated an amino acid at position 26 into a leucine" ; rdfs:subClassOf obo:CIDO_0000616 . obo:NCBITaxon_2591236 a rdfs:Class ; rdfs:label "Coronavirus BtRs-BetaCoV/YN2018C" ; rdfs:subClassOf obo:NCBITaxon_2720068 . a rdfs:Class ; rdfs:label "Skin Neoplasms [Disease/Finding]" ; rdfs:subClassOf , . obo:CIDO_0020290 a rdfs:Class ; rdfs:label "Sherlock CRISPR SARS-CoV-2 Kit" ; rdfs:seeAlso ; rdfs:subClassOf obo:CIDO_0000454 . a rdfs:Class ; rdfs:label "Sex Hormone Receptor Agonists [MoA]" ; rdfs:subClassOf . obo:OPMI_0000513 a rdfs:Class ; rdfs:label "provenance of procedure record"@en ; rdfs:comment "A provenance of record that determines the provenance of the Procedure record, as in whether the procedure was from an EHR system, insurance claim, registry, or other sources." ; rdfs:subClassOf obo:OPMI_0000512 . a rdfs:Class ; rdfs:label "Bcr-Abl Tyrosine Kinase Inhibitors [MoA]" ; rdfs:subClassOf . obo:DOID_12294 a rdfs:Class ; rdfs:label "atypical depressive disorder" ; rdfs:comment "A mood disorder that is characterized by mood reactivity and positivity, significant weight gain or increased appetite, excessive sleep or somnolence, a sensation of heaviness in limbs known as leaden paralysis, and significant social impairment as a consequence of hypersensitivity to perceived interpersonal rejection." ; rdfs:subClassOf obo:DOID_3324 . obo:VO_0000452 a rdfs:Class ; rdfs:label "preventive vaccine function" ; rdfs:comment "preventive vaccine function is a vaccine function realized by the process of vaccination and leading to induction of an adaptive immune response to the antigens in a vaccine, which protects against a specific disorder." ; rdfs:subClassOf obo:VO_0000278 . obo:NCBITaxon_1532164 a rdfs:Class ; rdfs:label "Alphacoronavirus BtCoV/GrNC1/Neo_cap/RSA/2012" ; rdfs:subClassOf obo:NCBITaxon_366617 . obo:CHEBI_29807 a rdfs:Class ; rdfs:label "glycyrrhizinate(3-)" ; rdfs:comment "A tricarboxylic acid trianion that is the conjugate base of glycyrrhizinic acid." ; rdfs:subClassOf obo:CHEBI_27092 . obo:CIDO_0000337 a rdfs:Class ; rdfs:label "AQALNTLVKQLSSNF"@en ; rdfs:subClassOf obo:CIDO_0000314 . obo:PR_000016330 a rdfs:Class ; rdfs:label "tyrosine-protein kinase receptor Tie-1" ; rdfs:comment "A receptor-type tyrosine-protein kinase Tie that is a translation product of the human TIE1 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000001923 . obo:CHEBI_33711 a rdfs:Class ; rdfs:label "C-terminal amino-acid residue" ; rdfs:comment "The residue in a peptide that has a free carboxyl group, or at least does not acylate another amino-acid residue, is called C-terminal." ; rdfs:subClassOf obo:CHEBI_33708 . obo:NCBITaxon_1503300 a rdfs:Class ; rdfs:label "BtRf-BetaCoV/SX2013" ; rdfs:subClassOf obo:NCBITaxon_694009 . a rdfs:Class ; rdfs:label "Mycoses [Disease/Finding]" ; rdfs:subClassOf . a rdfs:Class ; rdfs:label "Deoxycytidine [Chemical/Ingredient]" ; rdfs:subClassOf , . obo:UBERON_0001830 a rdfs:Class ; rdfs:label "minor salivary gland" ; rdfs:comment "One of the smaller, largely mucus-secreting, exocrine glands of the oral cavity, consisting of the labial, buccal, molar, lingual, and palatine glands[MP]." ; rdfs:subClassOf obo:UBERON_0000465 . obo:CIDO_0001070 a rdfs:Class ; rdfs:label "SARS-CoV2 Spike protein binding to human GOLGA7" ; rdfs:comment "SARS-CoV2 Spike protein binding to human GOLGA7, as evidented by an affinity-purification mass spectrometry experiment" ; rdfs:subClassOf obo:CIDO_0000060 . obo:NCBITaxon_1788428 a rdfs:Class ; rdfs:label "Bat coronavirus MsBtCoV/4068" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:NCBITaxon_296838 a rdfs:Class ; rdfs:label "SARS coronavirus PC4-137" ; rdfs:subClassOf obo:NCBITaxon_694009 . obo:CIDO_0020102 a rdfs:Class ; rdfs:label "cPass SARS-CoV-2 Neutralization Antibody Detection Kit" ; rdfs:seeAlso ; rdfs:subClassOf obo:CIDO_0000454 . obo:VO_0000106 a rdfs:Class ; rdfs:label "vaccine-induced T cell mediated immunity" ; rdfs:subClassOf obo:VO_0000135 . obo:CHEBI_35195 a rdfs:Class ; rdfs:label "surfactant" ; rdfs:comment "A substance which lowers the surface tension of the medium in which it is dissolved, and/or the interfacial tension with other phases, and, accordingly, is positively adsorbed at the liquid/vapour and/or at other interfaces." ; rdfs:subClassOf obo:CHEBI_63046 . obo:PR_000001449 a rdfs:Class ; rdfs:label "fibroblast growth factor receptor 2" ; rdfs:comment "A fibroblast growth factor receptor that is a translation product of the human FGFR2 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000001349 . obo:PR_P21917 a rdfs:Class ; rdfs:label "D(4) dopamine receptor (human)" ; rdfs:comment "A D(4) dopamine receptor that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000001179 , obo:PR_000029067 . obo:PR_Q8N568 a rdfs:Class ; rdfs:label "serine/threonine-protein kinase DCLK2 (human)" ; rdfs:comment "A serine/threonine-protein kinase DCLK2 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000006311 , obo:PR_000029067 . obo:CHEBI_32871 a rdfs:Class ; rdfs:label "prolinate" ; rdfs:comment "An alpha-amino-acid anion that is the conjugate base of proline, arising from deprotonation of the carboxy group." ; rdfs:subClassOf obo:CHEBI_33558 . obo:PR_Q9BQQ3 a rdfs:Class ; rdfs:label "Golgi reassembly-stacking protein 1 (human)" ; rdfs:comment "A Golgi reassembly-stacking protein 1 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000008149 , obo:PR_000029067 . obo:CHEBI_37956 a rdfs:Class ; rdfs:label "histamine antagonist" ; rdfs:comment "Histamine antagonists are the drugs that bind to but do not activate histamine receptors, thereby blocking the actions of histamine or histamine agonists." ; rdfs:subClassOf obo:CHEBI_37957 , obo:CHEBI_48706 . obo:CIDO_0020095 a rdfs:Class ; rdfs:label "COVID-19 Key" ; rdfs:seeAlso ; rdfs:subClassOf obo:CIDO_0000454 . obo:NCBITaxon_627431 a rdfs:Class ; rdfs:label "Feline coronavirus UU10" ; rdfs:subClassOf obo:NCBITaxon_12663 . obo:NCBITaxon_1329912 a rdfs:Class ; rdfs:label "Episquamata" ; rdfs:subClassOf obo:NCBITaxon_1329950 . obo:PR_000010269 a rdfs:Class ; rdfs:label "midasin" ; rdfs:comment "A protein that is a translation product of the human MDN1 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:NCBITaxon_1644140 a rdfs:Class ; rdfs:label "Bat coronavirus ANK011F" ; rdfs:subClassOf obo:NCBITaxon_696098 . obo:NCBITaxon_2163008 a rdfs:Class ; rdfs:label "Gammacoronavirus sp." ; rdfs:subClassOf obo:NCBITaxon_1433214 . obo:PR_Q8IYT8 a rdfs:Class ; rdfs:label "serine/threonine-protein kinase ULK2 (human)" ; rdfs:comment "A serine/threonine-protein kinase ULK2 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000017078 , obo:PR_000029067 . obo:CIDO_0000435 a rdfs:Class ; rdfs:label "motivation of replication"@en ; rdfs:comment "A movitation for self replication" ; rdfs:subClassOf obo:CIDO_0000434 . obo:NCBITaxon_231513 a rdfs:Class ; rdfs:label "Civet SARS CoV SZ3/2003" ; rdfs:subClassOf obo:NCBITaxon_694009 . obo:NCBITaxon_550977 a rdfs:Class ; rdfs:label "Bat coronavirus M.aus/Australia/CoV180/1996" ; rdfs:subClassOf obo:NCBITaxon_366617 . obo:PR_000001395 a rdfs:Class ; rdfs:label "interleukin-8" ; rdfs:comment "A protein that is a translation product of the human CXCL8 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:NCBITaxon_305408 a rdfs:Class ; rdfs:label "SARS coronavirus B029" ; rdfs:subClassOf obo:NCBITaxon_694009 . a rdfs:Class ; rdfs:label "Progesterone Congeners [Chemical/Ingredient]" ; rdfs:subClassOf . a rdfs:Class ; rdfs:label "Decreased Lipid Derived Immunologically Active Molecule Activity [PE]" ; rdfs:subClassOf . a rdfs:Class ; rdfs:label "Neuroendocrine Tumors [Disease/Finding]" ; rdfs:subClassOf . obo:CHEBI_29985 a rdfs:Class ; rdfs:label "L-glutamate(1-)" ; rdfs:comment "An alpha-amino-acid anion that is the conjugate base of L-glutamic acid, having anionic carboxy groups and a cationic amino group" ; rdfs:subClassOf obo:CHEBI_14321 , obo:CHEBI_62031 . obo:NCBITaxon_231472 a rdfs:Class ; rdfs:label "Avian infectious bronchitis virus (strain D1466)" ; rdfs:subClassOf obo:NCBITaxon_11120 . obo:NCBITaxon_2720538 a rdfs:Class ; rdfs:label "Betacoronavirus Erinaceus" ; rdfs:subClassOf obo:NCBITaxon_696098 . obo:PR_000007265 a rdfs:Class ; rdfs:label "exosome complex component RRP43" ; rdfs:comment "A protein that is a translation product of the human EXOSC8 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:PR_Q96MU8 a rdfs:Class ; rdfs:label "Kremen protein 1 (human)" ; rdfs:comment "A Kremen protein 1 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000009445 , obo:PR_000029067 . obo:NCBITaxon_1159902 a rdfs:Class ; rdfs:label "Common moorhen coronavirus HKU21" ; rdfs:subClassOf obo:NCBITaxon_2509474 . obo:NCBITaxon_1289546 a rdfs:Class ; rdfs:label "Coronavirus Mex_CoV-11a" ; rdfs:subClassOf obo:NCBITaxon_696098 . obo:CHEBI_24712 a rdfs:Class ; rdfs:label "hydroxymethyl group" ; rdfs:subClassOf obo:CHEBI_50325 . obo:CHEBI_24431 a rdfs:Class ; rdfs:label "chemical entity" ; rdfs:comment "A chemical entity is a physical entity of interest in chemistry including molecular entities, parts thereof, and chemical substances." ; rdfs:subClassOf obo:BFO_0000040 . obo:NCBITaxon_1346318 a rdfs:Class ; rdfs:label "Betacoronavirus BtCoV/Rhi_hip/Slo69/SLO/2009" ; rdfs:subClassOf obo:NCBITaxon_696098 . obo:PR_Q9H7Z7 a rdfs:Class ; rdfs:label "prostaglandin E synthase 2 (human)" ; rdfs:comment "A prostaglandin E synthase 2 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000013422 , obo:PR_000029067 . obo:NCBITaxon_441979 a rdfs:Class ; rdfs:label "Chinese ferret badger coronavirus Guangxi/F250/2006" ; rdfs:subClassOf obo:NCBITaxon_441985 . obo:IAO_0000104 a rdfs:Class ; rdfs:label "plan specification"@en ; rdfs:comment "a directive information entity that when concretized it is realized in a process in which the bearer tries to achieve the objectives, in part by taking the actions specified. Plan specifications includes parts such as objective specification, action specifications and conditional specifications."@en ; rdfs:subClassOf obo:IAO_0000033 . a rdfs:Class ; rdfs:label "Decreased Blood Pressure [PE]" ; rdfs:subClassOf . obo:CIDO_0000714 a rdfs:Class ; rdfs:label "AA variant pp1a SARS-CoV-2"@en ; rdfs:comment "An AA variant that is found within pp1a of SARS-CoV-2" ; rdfs:subClassOf obo:CIDO_0000602 . obo:CHEBI_79387 a rdfs:Class ; rdfs:label "trivalent inorganic anion" ; rdfs:comment "Any inorganic anion with a valency of three." ; rdfs:subClassOf obo:CHEBI_24834 . obo:NCBITaxon_32561 a rdfs:Class ; rdfs:label "Sauria" ; rdfs:subClassOf obo:NCBITaxon_8457 . obo:GO_0019229 a rdfs:Class ; rdfs:label "regulation of vasoconstriction" ; rdfs:comment "Any process that modulates the frequency, rate or extent of reductions in the diameter of blood vessels." ; rdfs:subClassOf obo:GO_0044057 , obo:GO_0097746 . obo:OAE_0000034 a rdfs:Class ; rdfs:label "fatigue AE" ; rdfs:comment "a behavior and neurological AE that has an outcome of fatigue, which is a state of awareness describing a range of afflictions, usually associated with physical and/or mental weakness, though varying from a general state of lethargy to a specific work-induced burning sensation within one's muscles. Physical fatigue is the inability to continue functioning at the level of one's normal abilities." ; rdfs:subClassOf obo:OAE_0000580 . obo:CHEBI_39141 a rdfs:Class ; rdfs:label "Bronsted acid" ; rdfs:comment "A molecular entity capable of donating a hydron to an acceptor (Bronsted base)." ; rdfs:subClassOf obo:CHEBI_17891 , obo:CHEBI_37527 . obo:PR_000015729 a rdfs:Class ; rdfs:label "stanniocalcin-2" ; rdfs:comment "A protein that is a translation product of the human STC2 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:NCBITaxon_1269306 a rdfs:Class ; rdfs:label "Coronavirus BtCoV/KCR291/Ano_geo/CRC/2010" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:CIDO_0000365 a rdfs:Class ; rdfs:label "personal protective equipment"@en ; rdfs:comment "protective equipment (such as clothing, helmet, goggles) that is designed to protect the wearer's body from injury or infection." ; rdfs:subClassOf obo:BFO_0000040 . obo:NCBITaxon_1269312 a rdfs:Class ; rdfs:label "Coronavirus BtCoV/KP256/Art_jam/PAN/2010" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:PR_000002200 a rdfs:Class ; rdfs:label "cytoplasmic tyrosine-protein kinase BMX" ; rdfs:comment "A TEC-type tyrosine-protein kinase that is a translation product of the human BMX gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000001967 . obo:OBI_0000680 a rdfs:Class ; rdfs:label "whole organism preparation" ; rdfs:comment "A material entity which is the output of a process in which one or more whole organisms are prepared in a way to make it easier to study them, and in which the great majority of organismal parts are maintained" ; rdfs:subClassOf obo:OBI_0100051 . obo:GO_0006605 a rdfs:Class ; rdfs:label "protein targeting" ; rdfs:comment "The process of targeting specific proteins to particular regions of the cell, typically membrane-bounded subcellular organelles. Usually requires an organelle specific protein sequence motif." ; rdfs:subClassOf obo:GO_0006886 . a rdfs:Class ; rdfs:label "Dopamine Receptor Interactions [MoA]" ; rdfs:subClassOf . obo:UBERON_0013755 a rdfs:Class ; rdfs:label "arterial blood" ; rdfs:comment "A blood that is part of a artery." ; rdfs:subClassOf obo:UBERON_0000178 . obo:NCBITaxon_1052263 a rdfs:Class ; rdfs:label "Bat coronavirus M.ful/Japan/04/2010" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:NCBITaxon_1076416 a rdfs:Class ; rdfs:label "Alphacoronavirus M.bly/B/Spain/2004" ; rdfs:subClassOf obo:NCBITaxon_366617 . obo:CHEBI_25872 a rdfs:Class ; rdfs:label "pentacyclic triterpenoid" ; rdfs:subClassOf obo:CHEBI_36615 , obo:CHEBI_51958 . obo:NCBITaxon_9837 a rdfs:Class ; rdfs:label "Camelus bactrianus" ; rdfs:subClassOf obo:NCBITaxon_9836 . obo:CIDO_0000646 a rdfs:Class ; rdfs:label "G662S in SARS-CoV-2 pp1b protein" ; rdfs:comment "An AA mutation or AA variant that has mutated an amino acid at position 662 into a serine in pp1b." ; rdfs:subClassOf obo:CIDO_0000715 , obo:CIDO_0001083 . obo:PR_000015080 a rdfs:Class ; rdfs:label "zinc transporter 7" ; rdfs:comment "A protein that is a translation product of the human SLC30A7 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:CHEBI_83821 a rdfs:Class ; rdfs:label "amino acid derivative" ; rdfs:comment "Any derivative of an amino acid resulting from reaction at an amino group, carboxy group, side-chain functional group, or from the replacement of any hydrogen by a heteroatom. The definition normally excludes peptides containing amino acid residues." ; rdfs:subClassOf obo:CHEBI_35352 . obo:HP_0033151 a rdfs:Class ; rdfs:label "Abnormal pharynx morphology" ; rdfs:comment "A structural anomaly of the pharynx." ; rdfs:subClassOf obo:HP_0012252 . obo:CIDO_0000863 a rdfs:Class ; rdfs:label "SARS-CoV2 nsp14 protein binding to human GLA" ; rdfs:comment "SARS-CoV2 nsp14 protein binding to human GLA, as evidented by an affinity-purification mass spectrometry experiment" ; rdfs:subClassOf obo:CIDO_0000059 . obo:PR_000005526 a rdfs:Class ; rdfs:label "chloride channel CLIC-like protein 1" ; rdfs:comment "A protein that is a translation product of the human CLCC1 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:PR_Q59H18 a rdfs:Class ; rdfs:label "serine/threonine-protein kinase TNNI3K (human)" ; rdfs:comment "A serine/threonine-protein kinase TNNI3K that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000016507 , obo:PR_000029067 . obo:NCBITaxon_379584 a rdfs:Class ; rdfs:label "Caniformia" ; rdfs:subClassOf obo:NCBITaxon_33554 . obo:CHEBI_10545 a rdfs:Class ; rdfs:label "electron" ; rdfs:comment "Elementary particle not affected by the strong force having a spin 1/2, a negative elementary charge and a rest mass of 0.000548579903(13) u, or 0.51099906(15) MeV." ; rdfs:subClassOf obo:CHEBI_36338 . obo:PR_000001161 a rdfs:Class ; rdfs:label "5-hydroxytryptamine receptor 1A" ; rdfs:comment "A 5-hydroxytryptamine receptor 1 that is a translation product of the human HTR1A gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000001098 . obo:NCBITaxon_42005 a rdfs:Class ; rdfs:label "Porcine hemagglutinating encephalomyelitis virus" ; rdfs:subClassOf obo:NCBITaxon_694003 . obo:CHEBI_76661 a rdfs:Class ; rdfs:label "EC 2.3.* (acyltransferase) inhibitor" ; rdfs:comment "A transferase inhibitor that interferes with the action of an acyltransferase (EC 2.3.*.*)." ; rdfs:subClassOf obo:CHEBI_71300 . obo:UBERON_0002072 a rdfs:Class ; rdfs:label "hypodermis" ; rdfs:comment "Lowermost layer of the integumentary system in vertebrates. Types of cells that are found in the hypodermis are fibroblasts, adipose cells, and macrophages. It is derived from the mesoderm, but unlike the dermis, it is not derived from the dermatome region of the mesoderm. The hypodermis is used mainly for fat storage[WP]." ; rdfs:subClassOf obo:UBERON_0000064 , obo:UBERON_0004120 . obo:NCBITaxon_422140 a rdfs:Class ; rdfs:label "Calf-giraffe coronavirus US/OH3/2006" ; rdfs:subClassOf obo:NCBITaxon_11128 . obo:CHEBI_36093 a rdfs:Class ; rdfs:label "inorganic chloride salt" ; rdfs:subClassOf obo:CHEBI_23114 , obo:CHEBI_24839 . obo:PR_000004773 a rdfs:Class ; rdfs:label "BMP-2-inducible protein kinase" ; rdfs:comment "A protein that is a translation product of the human BMP2K gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:UBERON_0001089 a rdfs:Class ; rdfs:label "sweat" ; rdfs:comment "Secretion produced by a sweat gland." ; rdfs:subClassOf obo:UBERON_0006314 . a rdfs:Class ; rdfs:label "AMODIAQUINE" ; rdfs:subClassOf . obo:OBI_0600024 a rdfs:Class ; rdfs:label "maintaining cell culture"@en ; rdfs:comment "a protocol application in which cells are kept alive in a defined environment outside of an organism. part of cell_culturing"@en ; rdfs:subClassOf obo:OBI_0000838 . obo:CIDO_0000415 a rdfs:Class ; rdfs:label "susceptibility to up-regulation in COVID-19 male patient"@en ; rdfs:comment "A disposition that a material entity such as a gene or protein is susceptible to be up-regulated in COVID-19 male patient" ; rdfs:subClassOf obo:CIDO_0000413 . obo:PR_000044633 a rdfs:Class ; rdfs:label "dopamine receptor" ; rdfs:comment "A rhodopsin-like G-protein coupled receptor that is a translation product of the human DRD1 to DRD5 genes, 1:1 orthologs thereof, or pro-orthologs thereof." ; rdfs:subClassOf obo:PR_000001094 . obo:PR_Q8NI60 a rdfs:Class ; rdfs:label "atypical kinase COQ8A, mitochondrial (human)" ; rdfs:comment "An atypical kinase COQ8A, mitochondrial that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000004929 , obo:PR_000029067 . obo:NCBITaxon_5762 a rdfs:Class ; rdfs:label "Naegleria gruberi" ; rdfs:subClassOf obo:NCBITaxon_5761 . obo:CIDO_0001123 a rdfs:Class ; rdfs:label "SARS-CoV2 orf8 protein binding to human NPC2"@en ; rdfs:comment "SARS-CoV2 orf8 protein binding to human NPC2, as evidented by an affinity-purification mass spectrometry experiment" ; rdfs:subClassOf obo:CIDO_0000051 . obo:OPMI_0000587 a rdfs:Class ; rdfs:label "payer plan period end date"@en ; rdfs:comment "A date when a payer plan period ends." ; rdfs:subClassOf obo:OPMI_0000584 . obo:PR_Q9H773 a rdfs:Class ; rdfs:label "dCTP pyrophosphatase 1 (human)" ; rdfs:comment "A dCTP pyrophosphatase 1 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000006329 , obo:PR_000029067 . obo:CHEBI_48705 a rdfs:Class ; rdfs:label "agonist" ; rdfs:comment "Substance which binds to cell receptors normally responding to naturally occurring substances and which produces a response of its own." ; rdfs:subClassOf obo:CHEBI_52210 . obo:CIDO_0000580 a rdfs:Class ; rdfs:label "SARS-CoV-2 Nsp2 protein interaction with host protein"@en ; rdfs:comment "A molecular interaction that has participant of the SARS-CoV-2 Nsp2 protein and a host protein" ; rdfs:subClassOf obo:CIDO_0000348 . obo:CHEBI_50336 a rdfs:Class ; rdfs:label "4-hydroxybenzyl group" ; rdfs:subClassOf obo:CHEBI_50325 . obo:DRON_00020931 a rdfs:Class ; rdfs:label "Benztropine Oral Tablet" ; rdfs:subClassOf obo:DRON_00000022 . obo:CIDO_0020041 a rdfs:Class ; rdfs:label "BD Max Covid-19 Assay" ; rdfs:seeAlso ; rdfs:subClassOf obo:CIDO_0000454 . obo:HP_0003077 a rdfs:Class ; rdfs:label "Hyperlipidemia" ; rdfs:comment "An elevated lipid concentration in the blood." ; rdfs:subClassOf obo:HP_0003119 . obo:CIDO_0000935 a rdfs:Class ; rdfs:label "SARS-CoV2 nsp8 protein binding to human MRPS2" ; rdfs:comment "SARS-CoV2 nsp8 protein binding to human MRPS2, as evidented by an affinity-purification mass spectrometry experiment" ; rdfs:subClassOf obo:CIDO_0000582 . a rdfs:Class ; rdfs:label "Lymphedema [Disease/Finding]" ; rdfs:subClassOf . obo:CIDO_0020084 a rdfs:Class ; rdfs:label "Color COVID-19 Self-Swab Collection Kit DTC" ; rdfs:seeAlso ; rdfs:subClassOf obo:CIDO_0000455 . obo:CHEBI_3533 a rdfs:Class ; rdfs:label "cephaeline" ; rdfs:comment "A pyridoisoquinoline comprising emetam having a hydroxy group at the 6'-position and methoxy substituents at the 7'-, 10- and 11-positions." ; rdfs:subClassOf obo:CHEBI_61692 . obo:CHEBI_138103 a rdfs:Class ; rdfs:label "inorganic acid" ; rdfs:comment "A Bronsted acid derived from one or more inorganic compounds. Inorganic acids (also known as mineral acids) form hydrons and conjugate base ions when dissolved in water." ; rdfs:subClassOf obo:CHEBI_39141 . obo:NCBITaxon_36391 a rdfs:Class ; rdfs:label "Canine enteric coronavirus INSAVC-1" ; rdfs:subClassOf obo:NCBITaxon_11153 . obo:HP_0012252 a rdfs:Class ; rdfs:label "Abnormal respiratory system morphology" ; rdfs:comment "A structural anomaly of the respiratory system." ; rdfs:subClassOf obo:HP_0002086 . obo:CIDO_0001138 a rdfs:Class ; rdfs:label "SARS-CoV2 orf8 protein binding to human NTPX1"@en ; rdfs:subClassOf obo:CIDO_0000051 . obo:CIDO_0000054 a rdfs:Class ; rdfs:label "SARS-CoV-2 Orf9c protein interaction with host protein"@en ; rdfs:comment "A molecular interaction that has participant of the SARS-CoV-2 Orf9c protein and a host protein" ; rdfs:subClassOf obo:CIDO_0000348 . obo:GO_0055082 a rdfs:Class ; rdfs:label "cellular chemical homeostasis" ; rdfs:comment "Any biological process involved in the maintenance of an internal steady state of a chemical at the level of the cell." ; rdfs:subClassOf obo:GO_0019725 , obo:GO_0048878 . obo:PR_Q6ZN16 a rdfs:Class ; rdfs:label "mitogen-activated protein kinase kinase kinase 15 (human)" ; rdfs:comment "A mitogen-activated protein kinase kinase kinase 15 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000010134 , obo:PR_000029067 . obo:GO_0006367 a rdfs:Class ; rdfs:label "transcription initiation from RNA polymerase II promoter" ; rdfs:comment "Any process involved in the assembly of the RNA polymerase II preinitiation complex (PIC) at an RNA polymerase II promoter region of a DNA template, resulting in the subsequent synthesis of RNA from that promoter. The initiation phase includes PIC assembly and the formation of the first few bonds in the RNA chain, including abortive initiation, which occurs when the first few nucleotides are repeatedly synthesized and then released. Promoter clearance, or release, is the transition between the initiation and elongation phases of transcription." ; rdfs:subClassOf obo:GO_0032774 . obo:CHEBI_27024 a rdfs:Class ; rdfs:label "toluenes" ; rdfs:comment "Any member of the class of benzenes that is a substituted benzene in which the substituents include one (and only one) methyl group." ; rdfs:subClassOf obo:CHEBI_22712 . obo:CHEBI_26440 a rdfs:Class ; rdfs:label "pyrimidine nucleoside" ; rdfs:subClassOf obo:CHEBI_33838 , obo:CHEBI_39447 . obo:NCBITaxon_1679878 a rdfs:Class ; rdfs:label "Coronavirus Hare_CoV/La06_383/Lep_gra/ESP/2006" ; rdfs:subClassOf obo:NCBITaxon_2664420 . a rdfs:Class ; rdfs:label "Urethral Diseases [Disease/Finding]" ; rdfs:subClassOf . obo:CHEBI_76946 a rdfs:Class ; rdfs:label "fungal metabolite" ; rdfs:comment "Any eukaryotic metabolite produced during a metabolic reaction in fungi, the kingdom that includes microorganisms such as the yeasts and moulds." ; rdfs:subClassOf obo:CHEBI_75763 . obo:PR_P23458 a rdfs:Class ; rdfs:label "tyrosine-protein kinase JAK1 (human)" ; rdfs:comment "A tyrosine-protein kinase JAK1 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000009196 , obo:PR_000029067 . a rdfs:Class ; rdfs:label "Emesis Suppression [PE]" ; rdfs:subClassOf , . obo:PR_Q6UX04 a rdfs:Class ; rdfs:label "spliceosome-associated protein CWC27 homolog (human)" ; rdfs:comment "A spliceosome-associated protein CWC27 homolog that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000014557 , obo:PR_000029067 . obo:NCBITaxon_681861 a rdfs:Class ; rdfs:label "Kenya bat coronavirus BtKY14" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:OBI_0002529 a rdfs:Class ; rdfs:label "pituitary gland specimen" ; rdfs:comment "A specimen that is derived from pituitary gland." ; rdfs:subClassOf obo:OBI_0001479 . obo:PR_O75592 a rdfs:Class ; rdfs:label "E3 ubiquitin-protein ligase MYCBP2 (human)" ; rdfs:comment "An E3 ubiquitin-protein ligase MYCBP2 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000029067 , obo:PR_000030251 . obo:UBERON_0000956 a rdfs:Class ; rdfs:label "cerebral cortex" ; rdfs:comment "The thin layer of gray matter on the surface of the cerebral hemisphere that develops from the telencephalon. It consists of the neocortex (6 layered cortex or isocortex), the hippocampal formation and the olfactory cortex." ; rdfs:subClassOf obo:UBERON_0000477 . obo:NCBITaxon_1018469 a rdfs:Class ; rdfs:label "Bat coronavirus Hipposideros/Ratcha-67/THA/2007" ; rdfs:subClassOf obo:NCBITaxon_366617 . obo:NCBITaxon_1269301 a rdfs:Class ; rdfs:label "Coronavirus BtCoV/KCR230/Pte_par/CRC/2010" ; rdfs:subClassOf obo:NCBITaxon_2664420 . a rdfs:Class ; rdfs:label "Nocodazole [Chemical/Ingredient]" ; rdfs:subClassOf . obo:GO_0019538 a rdfs:Class ; rdfs:label "protein metabolic process" ; rdfs:comment "The chemical reactions and pathways involving a protein. Includes protein modification." ; rdfs:subClassOf obo:GO_0043170 , obo:GO_0044238 , obo:GO_1901564 . obo:NCBITaxon_441985 a rdfs:Class ; rdfs:label "Guangxi coronaviridae" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:PR_000031382 a rdfs:Class ; rdfs:label "transmembrane protein 39B" ; rdfs:comment "A protein that is a translation product of the human TMEM39B gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:CIDO_0000945 a rdfs:Class ; rdfs:label "SARS-CoV2 nsp8 protein binding to human SRP54" ; rdfs:comment "SARS-CoV2 nsp8 protein binding to human SRP54, as evidented by an affinity-purification mass spectrometry experiment" ; rdfs:subClassOf obo:CIDO_0000582 . obo:CIDO_0000473 a rdfs:Class ; rdfs:label "VGGLYEIKIPTNFTI" ; rdfs:comment "A coronavirus epitope that is part of some S protein from HCoV HKU1 composed of the following amino acids VGGLYEIKIPTNFTI" ; rdfs:subClassOf obo:CIDO_0000450 . a rdfs:Class ; rdfs:label "Esophageal Diseases [Disease/Finding]" ; rdfs:subClassOf . obo:PR_000004100 a rdfs:Class ; rdfs:label "AP-2 complex subunit alpha-2" ; rdfs:comment "A protein that is a translation product of the human AP2A2 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:HP_0002094 a rdfs:Class ; rdfs:label "Dyspnea" ; rdfs:comment "Difficult or labored breathing. Dyspnea is a subjective feeling only the patient can rate, e.g., on a Borg scale." ; rdfs:subClassOf obo:HP_0002795 . obo:PR_P12268 a rdfs:Class ; rdfs:label "inosine-5'-monophosphate dehydrogenase 2 (human)" ; rdfs:comment "An inosine-5'-monophosphate dehydrogenase 2 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000009022 , obo:PR_000029067 . obo:GO_0046700 a rdfs:Class ; rdfs:label "heterocycle catabolic process" ; rdfs:comment "The chemical reactions and pathways resulting in the breakdown of heterocyclic compounds, those with a cyclic molecular structure and at least two different atoms in the ring (or rings)." ; rdfs:subClassOf obo:GO_0044248 , obo:GO_0046483 . obo:NCBITaxon_424359 a rdfs:Class ; rdfs:label "Bat coronavirus HKU4-1" ; rdfs:subClassOf obo:NCBITaxon_694007 . obo:PR_Q9H2X6 a rdfs:Class ; rdfs:label "homeodomain-interacting protein kinase 2 (human)" ; rdfs:comment "A homeodomain-interacting protein kinase 2 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000008567 , obo:PR_000029067 . obo:PR_000029067 a rdfs:Class ; rdfs:label "Homo sapiens protein" ; rdfs:comment "A protein that is encoded in the genome of Homo sapiens." ; rdfs:subClassOf obo:PR_000036194 . obo:UBERON_0002116 a rdfs:Class ; rdfs:label "ileum" ; rdfs:comment "the portion of the small intestine that extends from the jejunum to the colon" ; rdfs:subClassOf obo:UBERON_0000465 . obo:CIDO_0000091 a rdfs:Class ; rdfs:label "SARS-CoV entry to cell"@en ; rdfs:comment "A coronavirus-host interaction by which the SARS-CoV virus enters the host cell" ; rdfs:subClassOf obo:CIDO_0000085 . obo:CIDO_0000736 a rdfs:Class ; rdfs:label "SARS-CoV2 M protein binding to human AASS" ; rdfs:comment "SARS-CoV2 M protein binding to human AASS, as evidented by an affinity-purification mass spectrometry experiment" ; rdfs:subClassOf obo:CIDO_0000055 . obo:PR_000003725 a rdfs:Class ; rdfs:label "disintegrin and metalloproteinase domain-containing protein 9" ; rdfs:comment "A protein that is a translation product of the human ADAM9 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:OAE_0004579 a rdfs:Class ; rdfs:label "Level 4 TTS AE"@en ; rdfs:comment "A reported case as TTS but there is insufficient evidence to meet any level of the case." ; rdfs:subClassOf obo:OAE_0004540 . obo:CIDO_0001017 a rdfs:Class ; rdfs:label "GC-373" ; rdfs:subClassOf obo:CHEBI_23367 . obo:OBI_0002500 a rdfs:Class ; rdfs:label "amniotic fluid specimen" ; rdfs:comment "A specimen that is derived from amniotic fluid." ; rdfs:subClassOf obo:OBI_0001479 . obo:NCBITaxon_391355 a rdfs:Class ; rdfs:label "SARS coronavirus Frankfurt1-v01" ; rdfs:subClassOf obo:NCBITaxon_229992 . obo:CHEBI_32866 a rdfs:Class ; rdfs:label "L-prolino group" ; rdfs:subClassOf obo:CHEBI_32873 , obo:CHEBI_33717 , obo:CHEBI_83228 . obo:VO_0000002 a rdfs:Class ; rdfs:label "vaccination" ; rdfs:comment "a process of administering substance in vivo that involves in adding a vaccine into a host (e.g., human) in vivo with the intent to invoke a protective or therapeutic adaptive immune response." ; rdfs:subClassOf obo:OBI_0600007 . obo:CIDO_0020001 a rdfs:Class ; rdfs:label "Abbott RealTime SARS-CoV-2 EUA test" ; rdfs:seeAlso ; rdfs:subClassOf obo:CIDO_0000454 . obo:CHEBI_5924 a rdfs:Class ; rdfs:label "EC 3.4.21.* (serine endopeptidase) inhibitor" ; rdfs:comment "Any EC 3.4.* (hydrolases acting on peptide bond) inhibitor that inhibits the activity of a serine endopeptidase (EC 3.4.21.*)." ; rdfs:subClassOf obo:CHEBI_60258 . obo:NCBITaxon_249065 a rdfs:Class ; rdfs:label "SARS coronavirus GZ-D" ; rdfs:subClassOf obo:NCBITaxon_694009 . obo:CIDO_0001163 a rdfs:Class ; rdfs:label "AA variant in SARS-CoV-2 S protein S2 CD region"@en ; rdfs:subClassOf obo:CIDO_0000595 . obo:NCBITaxon_11132 a rdfs:Class ; rdfs:label "Bovine coronavirus Mebus" ; rdfs:subClassOf obo:NCBITaxon_11128 . obo:CIDO_0000585 a rdfs:Class ; rdfs:label "SARS-CoV-2 orf3b protein interaction with host protein"@en ; rdfs:comment "A molecular interaction that has participant of the SARS-CoV-2 orf3b protein and a host protein" ; rdfs:subClassOf obo:CIDO_0000348 . obo:CIDO_0020181 a rdfs:Class ; rdfs:label "Kroger Health COVID-19 Test Home Collection Kit" ; rdfs:seeAlso ; rdfs:subClassOf obo:CIDO_0000455 . obo:PR_Q99081 a rdfs:Class ; rdfs:label "transcription factor 12 (human)" ; rdfs:comment "A transcription factor 12 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000016176 , obo:PR_000029067 . obo:CHEBI_62031 a rdfs:Class ; rdfs:label "polar amino acid zwitterion" ; rdfs:comment "Zwitterionic form of a polar amino acid having an anionic carboxy group and a protonated amino group." ; rdfs:subClassOf obo:CHEBI_35238 . obo:CHEBI_15960 a rdfs:Class ; rdfs:label "O-acetylcarnitinium" ; rdfs:subClassOf obo:CHEBI_35267 . obo:HP_0001513 a rdfs:Class ; rdfs:label "Obesity" ; rdfs:comment "Accumulation of substantial excess body fat." ; rdfs:subClassOf obo:HP_0000118 . obo:PR_P11940 a rdfs:Class ; rdfs:label "polyadenylate-binding protein 1 (human)" ; rdfs:comment "A polyadenylate-binding protein 1 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000012204 , obo:PR_000029067 . obo:OAE_0000357 a rdfs:Class ; rdfs:label "throat tightness AE" ; rdfs:comment "a sensory capability AE that has an outcome of a sensation of tightness in the throat" ; rdfs:subClassOf obo:OAE_0000582 . obo:PR_000016507 a rdfs:Class ; rdfs:label "serine/threonine-protein kinase TNNI3K" ; rdfs:comment "A protein that is a translation product of the human TNNI3K gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:CHEBI_76773 a rdfs:Class ; rdfs:label "EC 3.1.1.* (carboxylic ester hydrolase) inhibitor" ; rdfs:comment "An EC 3.1.* (ester hydrolase) inhibitor that interferes with the action of a carboxylic ester hydrolase (EC 3.1.1.*)." ; rdfs:subClassOf obo:CHEBI_76760 . obo:CIDO_0000426 a rdfs:Class ; rdfs:label "MERS diagnostic process"@en ; rdfs:comment "A diagnostic process for detecting MERS from a patient" ; rdfs:subClassOf obo:CIDO_0000423 . obo:VO_0005165 a rdfs:Class ; rdfs:label "AG0301-COVID19" ; rdfs:comment "A SARS-CoV-2 DNA vaccine developed by AnGes." ; rdfs:subClassOf obo:VO_0005203 . obo:PR_Q13547 a rdfs:Class ; rdfs:label "histone deacetylase 1 (human)" ; rdfs:comment "A histone deacetylase 1 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000008478 , obo:PR_000029067 . obo:OPMI_0000554 a rdfs:Class ; rdfs:label "device exposure"@en ; rdfs:comment "A process of a person’s exposure to a foreign physical object or instrument which is used for diagnostic or therapeutic purposes through a mechanism beyond chemical action. Devices include implantable objects (e.g. pacemakers, stents, artificial joints), medical equipment and supplies (e.g. bandages, crutches, syringes), other instruments used in medical procedures (e.g. sutures, defibrillators) and material used in clinical care (e.g. adhesives, body material, dental material, surgical material)." ; rdfs:seeAlso obo:NCIT_C102617 ; rdfs:subClassOf obo:BFO_0000015 . obo:PR_Q14994 a rdfs:Class ; rdfs:label "nuclear receptor subfamily 1 group I member 3 (human)" ; rdfs:comment "A nuclear receptor subfamily 1 group I member 3 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000011398 , obo:PR_000029067 . obo:CIDO_0000199 a rdfs:Class ; rdfs:label "host-SARS-CoV interaction"@en ; rdfs:subClassOf obo:CIDO_0000084 . a rdfs:Class ; rdfs:label "Neuroectodermal Tumors [Disease/Finding]" ; rdfs:subClassOf , . obo:OAE_0000185 a rdfs:Class ; rdfs:label "thrombosis AE" ; rdfs:comment "A vascular disorder AE that results in the presence of blood clot along the wall of a blood vessel, frequently causing vascular obstruction. Some authorities differentiate thrombus formation from simple coagulation or clot formation." ; rdfs:subClassOf obo:OAE_0000085 . obo:CHEBI_35235 a rdfs:Class ; rdfs:label "L-cysteine zwitterion" ; rdfs:subClassOf obo:CHEBI_35237 . obo:PR_Q5VUA4 a rdfs:Class ; rdfs:label "zinc finger protein 318 (human)" ; rdfs:comment "A zinc finger protein 318 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000017821 , obo:PR_000029067 . a rdfs:Class ; rdfs:label "14-alpha Demethylase Inhibitors [MoA]" ; rdfs:subClassOf . obo:NCBITaxon_2794340 a rdfs:Class ; rdfs:label "Montifringilla taczanowskii coronavirus N" ; rdfs:subClassOf obo:NCBITaxon_1232736 . obo:DRON_00020654 a rdfs:Class ; rdfs:label "Ivermectin Oral Tablet" ; rdfs:subClassOf obo:DRON_00000022 . obo:NCBITaxon_2042588 a rdfs:Class ; rdfs:label "Coronavirus PREDICT CoV-64" ; rdfs:subClassOf obo:NCBITaxon_696098 . obo:NCBITaxon_39099 a rdfs:Class ; rdfs:label "Pantherophis obsoletus" ; rdfs:subClassOf obo:NCBITaxon_201800 . obo:CIDO_0000010 a rdf:Property ; rdfs:label "is host of"@en ; rdfs:range . obo:NCBITaxon_906885 a rdfs:Class ; rdfs:label "Feline coronavirus UU20" ; rdfs:subClassOf obo:NCBITaxon_12663 . obo:PR_P42680 a rdfs:Class ; rdfs:label "tyrosine-protein kinase Tec (human)" ; rdfs:comment "A tyrosine-protein kinase Tec that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000002240 , obo:PR_000029067 . obo:NCBITaxon_1117224 a rdfs:Class ; rdfs:label "Bat coronavirus 2265/Philippines/2010" ; rdfs:subClassOf obo:NCBITaxon_696098 . obo:NCBITaxon_2509479 a rdfs:Class ; rdfs:label "Decacovirus" ; rdfs:subClassOf obo:NCBITaxon_693996 . obo:NCBITaxon_1325690 a rdfs:Class ; rdfs:label "Coronavirus Susurluk10" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:NCBITaxon_264388 a rdfs:Class ; rdfs:label "SARS coronavirus TW-PH2" ; rdfs:subClassOf obo:NCBITaxon_264370 . obo:PR_P16234 a rdfs:Class ; rdfs:label "platelet-derived growth factor receptor alpha (human)" ; rdfs:comment "An alpha-type platelet-derived growth factor receptor that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000002030 , obo:PR_000029067 . obo:UBERON_0001913 a rdfs:Class ; rdfs:label "milk" ; rdfs:comment "An emulsion of fat globules within a fluid that is secreted by the mammary gland during lactation." ; rdfs:subClassOf obo:UBERON_0006314 . obo:CIDO_0001085 a rdfs:Class ; rdfs:label "AA variant in SARS-CoV-2 nsp14 protein"@en ; rdfs:comment "An AA variant in SARS-CoV-2 nsp14 protein. Equivalent to an AA variant in SARS-CoV-2 rep 1ab with an AA position of 5903 - 6429." ; rdfs:subClassOf obo:CIDO_0000715 . obo:CIDO_0000532 a rdfs:Class ; rdfs:label "NPVSFVVKPVCSSIF" ; rdfs:comment "A coronavirus epitope that is part of some S protein from HCoV 229E composed of the following amino acids NPVSFVVKPVCSSIF" ; rdfs:subClassOf obo:CIDO_0000451 . obo:NCBITaxon_1679889 a rdfs:Class ; rdfs:label "Coronavirus RCoV/D_RMU10_1919/Myo_gla/GER/2010" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:PR_000007127 a rdfs:Class ; rdfs:label "ephrin type-A receptor 7" ; rdfs:comment "An ephrin receptor that is a translation product of the human EPHA7 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000025845 . obo:DRON_00014099 a rdfs:Class ; rdfs:label "Fluspirilene" ; rdfs:subClassOf obo:OBI_0000047 . obo:NCBITaxon_389235 a rdfs:Class ; rdfs:label "Bat coronavirus (BtCoV/310A /2005)" ; rdfs:subClassOf obo:NCBITaxon_389126 . obo:CHEBI_35267 a rdfs:Class ; rdfs:label "quaternary ammonium ion" ; rdfs:comment "A derivative of ammonium, NH4(+), in which all four of the hydrogens bonded to nitrogen have been replaced with univalent (usually organyl) groups." ; rdfs:subClassOf obo:CHEBI_25697 , obo:CHEBI_35274 . obo:NCBITaxon_2023658 a rdfs:Class ; rdfs:label "Tylonycteris bat alphacoronavirus" ; rdfs:subClassOf obo:NCBITaxon_366617 . obo:NCBITaxon_903625 a rdfs:Class ; rdfs:label "Kenya bat coronavirus BtKY87" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:NCBITaxon_264377 a rdfs:Class ; rdfs:label "SARS coronavirus TW-KC3" ; rdfs:subClassOf obo:NCBITaxon_264370 . obo:CHEBI_25806 a rdfs:Class ; rdfs:label "oxygen molecular entity" ; rdfs:subClassOf obo:CHEBI_33304 . obo:PR_000002110 a rdfs:Class ; rdfs:label "tyrosine-protein kinase BTK" ; rdfs:comment "A TEC-type tyrosine-protein kinase that is a translation product of the human BTK gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000001967 . obo:GO_0033674 a rdfs:Class ; rdfs:label "positive regulation of kinase activity" ; rdfs:comment "Any process that activates or increases the frequency, rate or extent of kinase activity, the catalysis of the transfer of a phosphate group, usually from ATP, to a substrate molecule." ; rdfs:subClassOf obo:GO_0042327 , obo:GO_0043549 , obo:GO_0051347 . obo:GO_0090218 a rdfs:Class ; rdfs:label "positive regulation of lipid kinase activity" ; rdfs:comment "Any process that increases the frequency, rate or extent of lipid kinase activity, the catalysis of the transfer of a phosphate group, usually from ATP, to a simple or complex lipid." ; rdfs:subClassOf obo:GO_0033674 , obo:GO_0043550 , obo:GO_0045834 . obo:PR_Q08117 a rdfs:Class ; rdfs:label "TLE family member 5 (human)" ; rdfs:comment "A TLE family member 5 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000003800 , obo:PR_000029067 . obo:DRON_00000037 a rdfs:Class ; rdfs:label "function-activating mu receptor binding disposition" ; rdfs:comment "a disposition of a molecule to bind an instance of a mu opioid receptor in a manner that activates the realization of a biological function of the receptor instance​"@en ; rdfs:subClassOf obo:BFO_0000016 . obo:PR_P28300 a rdfs:Class ; rdfs:label "protein-lysine 6-oxidase (human)" ; rdfs:comment "A protein-lysine 6-oxidase that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000009883 , obo:PR_000029067 . obo:CHEBI_35526 a rdfs:Class ; rdfs:label "hypoglycemic agent" ; rdfs:comment "A drug which lowers the blood glucose level." ; rdfs:subClassOf obo:CHEBI_23888 . obo:CIDO_0000170 a rdfs:Class ; rdfs:label "COVID-19 experimental drug"@en ; rdfs:subClassOf obo:CIDO_0000169 . obo:PR_000013030 a rdfs:Class ; rdfs:label "NADPH--cytochrome P450 reductase" ; rdfs:comment "A protein that is a translation product of the human POR gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:CIDO_0000934 a rdfs:Class ; rdfs:label "SARS-CoV2 nsp8 protein binding to human MPHOSPH10" ; rdfs:comment "SARS-CoV2 nsp8 protein binding to human MPHOSPH10, as evidented by an affinity-purification mass spectrometry experiment" ; rdfs:subClassOf obo:CIDO_0000582 . a rdfs:Class ; rdfs:label "Clomipramine Hydrochloride [Chemical/Ingredient]" ; rdfs:subClassOf . obo:PR_Q9BVL2 a rdfs:Class ; rdfs:label "nucleoporin p58/p45 (human)" ; rdfs:comment "A nucleoporin p58/p45 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000011527 , obo:PR_000029067 . obo:CIDO_0000643 a rdfs:Class ; rdfs:label "S3675- in SARS-CoV-2 pp1a protein" ; rdfs:comment "An AA mutation or AA variant that has mutated an amino acid at position 3675 into a deletion" ; rdfs:subClassOf obo:CIDO_0001147 . obo:PR_P15151 a rdfs:Class ; rdfs:label "poliovirus receptor (human)" ; rdfs:comment "A poliovirus receptor that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000002067 , obo:PR_000029067 . obo:CHEBI_35314 a rdfs:Class ; rdfs:label "glycosiduronic acid" ; rdfs:subClassOf obo:CHEBI_24400 . obo:OPMI_0000565 a rdfs:Class ; rdfs:label "drug exposure start date"@en ; rdfs:comment "The date on which a drug exposure starts." ; rdfs:subClassOf obo:OPMI_0000564 . obo:PR_000015754 a rdfs:Class ; rdfs:label "serine/threonine-protein kinase 38" ; rdfs:comment "A protein that is a translation product of the human STK38 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:CIDO_0001006 a rdfs:Class ; rdfs:label "N4-Hydroxycytidine" ; rdfs:subClassOf obo:CHEBI_23367 . obo:CHEBI_36344 a rdfs:Class ; rdfs:label "hadron" ; rdfs:comment "Hadron is a subatomic particle which experiences the strong force." ; rdfs:subClassOf obo:CHEBI_36343 . obo:PR_P50897 a rdfs:Class ; rdfs:label "palmitoyl-protein thioesterase 1 (human)" ; rdfs:comment "A palmitoyl-protein thioesterase 1 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000013160 , obo:PR_000029067 . obo:PR_000013695 a rdfs:Class ; rdfs:label "Ras-related protein Ral-A" ; rdfs:comment "A protein that is a translation product of the human RALA gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . a rdfs:Class ; rdfs:label "TAMOXIFEN" ; rdfs:subClassOf . obo:NCBITaxon_749435 a rdfs:Class ; rdfs:label "Rock sandpiper coronavirus CIR-65828" ; rdfs:subClassOf obo:NCBITaxon_749416 . obo:DRON_00016250 a rdfs:Class ; rdfs:label "Digitoxin" ; rdfs:subClassOf obo:OBI_0000047 . obo:PR_P09619 a rdfs:Class ; rdfs:label "platelet-derived growth factor receptor beta (human)" ; rdfs:comment "A beta-type platelet-derived growth factor receptor that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000002035 , obo:PR_000029067 . obo:CHEBI_37445 a rdfs:Class ; rdfs:label "folic acids" ; rdfs:comment "A group of heterocyclic compounds based on the pteroic acid skeleton conjugated with one or more L-glutamic acid units." ; rdfs:subClassOf obo:CHEBI_176842 , obo:CHEBI_26375 , obo:CHEBI_83982 . obo:NCBITaxon_1963758 a rdfs:Class ; rdfs:label "Myomorpha" ; rdfs:subClassOf obo:NCBITaxon_9989 . obo:NCBITaxon_31630 a rdfs:Class ; rdfs:label "Avian infectious bronchitis virus (strain UK/68/84)" ; rdfs:subClassOf obo:NCBITaxon_11120 . obo:NCBITaxon_1288690 a rdfs:Class ; rdfs:label "Bat coronavirus POA/2012/143" ; rdfs:subClassOf obo:NCBITaxon_366617 . obo:HP_0006530 a rdfs:Class ; rdfs:label "Abnormal pulmonary Interstitial morphology" ; rdfs:comment "Abnormality of the lung parenchyma extending to the pulmonary interstitium and leading to diffuse pulmonary fibrosis." ; rdfs:subClassOf obo:HP_0002088 . obo:CHEBI_38166 a rdfs:Class ; rdfs:label "organic heteropolycyclic compound" ; rdfs:subClassOf obo:CHEBI_24532 , obo:CHEBI_33671 . obo:CHEBI_33655 a rdfs:Class ; rdfs:label "aromatic compound" ; rdfs:comment "A cyclically conjugated molecular entity with a stability (due to delocalization) significantly greater than that of a hypothetical localized structure (e.g. Kekule structure) is said to possess aromatic character." ; rdfs:subClassOf obo:CHEBI_33595 . obo:VO_0000884 a rdfs:Class ; rdfs:label "aluminum vaccine adjuvant" ; rdfs:comment "a mineral salt vaccine adjuvant that is composed of aluminum salt." ; rdfs:subClassOf obo:VO_0000093 . obo:NCBITaxon_497945 a rdfs:Class ; rdfs:label "Bat coronavirus P.nat/Germany/D5.73/2007" ; rdfs:subClassOf obo:NCBITaxon_366617 . obo:PR_Q92769 a rdfs:Class ; rdfs:label "histone deacetylase 2 (human)" ; rdfs:comment "A histone deacetylase 2 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000008481 , obo:PR_000029067 . obo:GO_0046777 a rdfs:Class ; rdfs:label "protein autophosphorylation" ; rdfs:comment "The phosphorylation by a protein of one or more of its own amino acid residues (cis-autophosphorylation), or residues on an identical protein (trans-autophosphorylation)." ; rdfs:subClassOf obo:GO_0006468 . obo:CHEBI_38275 a rdfs:Class ; rdfs:label "pyrrolidinone" ; rdfs:subClassOf obo:CHEBI_38260 . obo:PR_000007210 a rdfs:Class ; rdfs:label "estrogen-related receptor gamma" ; rdfs:comment "A protein that is a translation product of the human ESRRG gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:PR_000010135 a rdfs:Class ; rdfs:label "mitogen-activated protein kinase kinase kinase 2" ; rdfs:comment "A protein that is a translation product of the human MAP3K2 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:CIDO_0000768 a rdfs:Class ; rdfs:label "SARS-CoV2 M protein binding to human SLC25A21" ; rdfs:comment "SARS-CoV2 M protein binding to human SLC25A21, as evidented by an affinity-purification mass spectrometry experiment" ; rdfs:subClassOf obo:CIDO_0000055 . obo:PR_000012721 a rdfs:Class ; rdfs:label "phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform" ; rdfs:comment "A protein that is a translation product of the human PIK3CD gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:GO_0098542 a rdfs:Class ; rdfs:label "defense response to other organism" ; rdfs:comment "Reactions triggered in response to the presence of another organism that act to protect the cell or organism from damage caused by that organism." ; rdfs:subClassOf obo:GO_0006952 , obo:GO_0051707 . obo:NCBITaxon_227998 a rdfs:Class ; rdfs:label "SARS coronavirus Hong Kong/03/2003" ; rdfs:subClassOf obo:NCBITaxon_694009 . obo:PR_O75385 a rdfs:Class ; rdfs:label "serine/threonine-protein kinase ULK1 (human)" ; rdfs:comment "A serine/threonine-protein kinase ULK1 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000017077 , obo:PR_000029067 . obo:CHEBI_29987 a rdfs:Class ; rdfs:label "glutamate(2-)" ; rdfs:comment "A dicarboxylic acid dianion that is the conjugate base of glutamate(1-)." ; rdfs:subClassOf obo:CHEBI_28965 . obo:PR_P0C7P0 a rdfs:Class ; rdfs:label "CDGSH iron-sulfur domain-containing protein 3, mitochondrial (human)" ; rdfs:comment "A CDGSH iron-sulfur domain-containing protein 3, mitochondrial that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000029067 , obo:PR_000030840 . obo:VO_0005256 a rdfs:Class ; rdfs:label "HDT-301"@en ; rdfs:comment "A SARS-CoV-2 Lipid-Inorganic Nanoparticle (LION™) formulated replicating mRNA vaccine that encodes for a full-length spike (S) protein of the SARS-CoV-2 virus" ; rdfs:subClassOf obo:VO_0005198 . obo:OPMI_0000572 a rdfs:Class ; rdfs:label "drug exposure"@en ; rdfs:comment "An exposure or contact of a person to a drug. The drug exposure includes drug dispensing or administration for a person." ; rdfs:subClassOf obo:BFO_0000015 . obo:CIDO_0000641 a rdfs:Class ; rdfs:label "P3395H in SARS-CoV-2 pp1a protein" ; rdfs:comment "An AA mutation or AA variant that has mutated an amino acid at position 3395 into a histidine in pp1a." ; rdfs:subClassOf obo:CIDO_0001076 . obo:APOLLO_SV_00000553 a rdfs:Class ; rdfs:label "two-strain Susceptible-Infectious-Resistant model"@en ; rdfs:comment "A Susceptible-Infected-Resistant model that represents exactly two infections in ecosystem by exactly two pathogens."@en ; rdfs:subClassOf obo:APOLLO_SV_00000549 . obo:CHEBI_32828 a rdfs:Class ; rdfs:label "D-threoninium" ; rdfs:comment "The D-enantiomer of threoninium." ; rdfs:subClassOf obo:CHEBI_32833 . a rdfs:Class ; rdfs:label "Stimulation Small Intestine Fluid/Electrolyte Absorption [PE]" ; rdfs:subClassOf . obo:GO_0005216 a rdfs:Class ; rdfs:label "ion channel activity" ; rdfs:comment "Enables the facilitated diffusion of an ion (by an energy-independent process) by passage through a transmembrane aqueous pore or channel without evidence for a carrier-mediated mechanism. May be either selective (it enables passage of a specific ion only) or non-selective (it enables passage of two or more ions of same charge but different size)." ; rdfs:subClassOf obo:GO_0015075 , obo:GO_0015267 , obo:GO_0015318 . obo:GO_0051049 a rdfs:Class ; rdfs:label "regulation of transport" ; rdfs:comment "Any process that modulates the frequency, rate or extent of the directed movement of substances (such as macromolecules, small molecules, ions) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." ; rdfs:subClassOf obo:GO_0032879 . obo:NCBITaxon_1346307 a rdfs:Class ; rdfs:label "Betacoronavirus BtCoV/Rhi_hip/R07-09/SPA/2010" ; rdfs:subClassOf obo:NCBITaxon_696098 . obo:PR_O14786 a rdfs:Class ; rdfs:label "neuropilin-1 (human)" ; rdfs:comment "A neuropilin-1 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000001900 , obo:PR_000029067 . obo:GO_0045087 a rdfs:Class ; rdfs:label "innate immune response" ; rdfs:comment "Innate immune responses are defense responses mediated by germline encoded components that directly recognize components of potential pathogens." ; rdfs:subClassOf obo:GO_0006955 , obo:GO_0098542 . obo:GO_0009891 a rdfs:Class ; rdfs:label "positive regulation of biosynthetic process" ; rdfs:comment "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of substances." ; rdfs:subClassOf obo:GO_0009889 , obo:GO_0009893 . obo:PR_000012442 a rdfs:Class ; rdfs:label "cyclin-dependent kinase 17" ; rdfs:comment "A CDK2-related kinase that is a translation product of the human CDK17 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000003270 . obo:OBI_0000922 a rdfs:Class ; rdfs:label "frozen specimen" ; rdfs:comment "A specimen that has been frozen in order to store it." ; rdfs:subClassOf obo:OBI_0001472 . obo:NCBITaxon_215681 a rdfs:Class ; rdfs:label "Canine respiratory coronavirus" ; rdfs:subClassOf obo:NCBITaxon_694003 . obo:CHEBI_22562 a rdfs:Class ; rdfs:label "anilines" ; rdfs:comment "Any aromatic amine that is benzene carrying at least one amino substituent and its substituted derivatives." ; rdfs:subClassOf obo:CHEBI_22712 , obo:CHEBI_33860 . obo:CHEBI_60834 a rdfs:Class ; rdfs:label "beta-carbolines" ; rdfs:comment "Any pyridoindole containing a beta-carboline skeleton and their hydrogenated derivatives" ; rdfs:subClassOf obo:CHEBI_48888 . obo:NCBITaxon_1717204 a rdfs:Class ; rdfs:label "Coronavirus PREDICT_CoV-49" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:NCBITaxon_1076425 a rdfs:Class ; rdfs:label "Alphacoronavirus P.sp/K/Spain/2007" ; rdfs:subClassOf obo:NCBITaxon_366617 . obo:NCBITaxon_267392 a rdfs:Class ; rdfs:label "SARS coronavirus SinP3" ; rdfs:subClassOf obo:NCBITaxon_694009 . obo:NCBITaxon_5745 a rdfs:Class ; rdfs:subClassOf obo:OBI_0100026 . obo:PR_000001324 a rdfs:Class ; rdfs:label "basigin" ; rdfs:comment "A protein that is a translation product of the human BSG gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:GO_0097305 a rdfs:Class ; rdfs:label "response to alcohol" ; rdfs:comment "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an alcohol stimulus." ; rdfs:subClassOf obo:GO_0010033 , obo:GO_1901700 . obo:PR_000010633 a rdfs:Class ; rdfs:label "28S ribosomal protein S25, mitochondrial" ; rdfs:comment "A protein that is a translation product of the human MRPS25 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:DRON_00000032 a rdfs:Class ; rdfs:label "drug product therapeutic function"@en ; rdfs:comment "a function inhering in a drug product that when realized, is realized by a process that either (1) negatively regulates symptom processes, processes leading to symptoms, and/or the realization of a disease, (2) has specified output some entity useful in the diagnosis of disease, or (3) negatively regulates or blocks etiological processes."@en ; rdfs:subClassOf obo:BFO_0000034 . obo:PR_P12314 a rdfs:Class ; rdfs:label "high affinity immunoglobulin gamma Fc receptor I (human)" ; rdfs:comment "A high affinity immunoglobulin gamma Fc receptor I that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000001465 , obo:PR_000029067 . obo:GO_0009611 a rdfs:Class ; rdfs:label "response to wounding" ; rdfs:comment "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating damage to the organism." ; rdfs:subClassOf obo:GO_0006950 . a rdfs:Class ; rdfs:label "Salicylamides [Chemical/Ingredient]" ; rdfs:subClassOf . obo:NCBITaxon_1288684 a rdfs:Class ; rdfs:label "Bat coronavirus Mr/Shanxi2011" ; rdfs:subClassOf obo:NCBITaxon_366617 . obo:CHEBI_21731 a rdfs:Class ; rdfs:label "N-glycosyl compound" ; rdfs:comment "A glycosyl compound arising formally from the elimination of water from a glycosidic hydroxy group and an H atom bound to a nitrogen atom, thus creating a C-N bond." ; rdfs:subClassOf obo:CHEBI_35352 , obo:CHEBI_63161 , obo:CHEBI_63299 . obo:PR_Q00537 a rdfs:Class ; rdfs:label "cyclin-dependent kinase 17 (human)" ; rdfs:comment "A cyclin-dependent kinase 17 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000012442 , obo:PR_000029067 . obo:OMRSE_00000010 a rdfs:Class ; rdfs:label "human health care role"@en ; rdfs:comment "A role in human social processes that is realized by health care processes such as seeking or providing treatment for disease and injury, diagnosing disease and injury, or undergoing diagnosis. "@en ; rdfs:subClassOf obo:OMRSE_00000024 . obo:PR_P03372 a rdfs:Class ; rdfs:label "estrogen receptor (human)" ; rdfs:comment "An estrogen receptor that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000007204 , obo:PR_000029067 . obo:OBCS_0000059 a rdfs:Class ; rdfs:label "specificity" ; rdfs:comment "A data item that refers to the proportion of negatives in a binary classification test which are correctly identified" ; rdfs:subClassOf obo:OBCS_0000220 . a rdfs:Class ; rdfs:label "Arthritis, Rheumatoid [Disease/Finding]" ; rdfs:subClassOf , , . obo:CIDO_0020240 a rdfs:Class ; rdfs:label "PowerChek 2019-nCoV Real-time PCR Kit" ; rdfs:seeAlso ; rdfs:subClassOf obo:CIDO_0000454 . a rdfs:Class ; rdfs:label "Norepinephrine Activity Alteration [PE]" ; rdfs:subClassOf . obo:NCBITaxon_258781 a rdfs:Class ; rdfs:label "Pheasant coronavirus" ; rdfs:subClassOf obo:NCBITaxon_694014 . obo:CIDO_0000028 a rdfs:Class ; rdfs:label "COVID-19 diagnostic process based on symptoms"@en ; rdfs:comment "A COVID-19 diagnostic process that identifies typical phenotypes (symptoms) of a patient and makes a diagnostic conclusion." ; rdfs:subClassOf obo:CIDO_0000424 . obo:VO_0005267 a rdfs:Class ; rdfs:label "authorized COVID-19 recombinant vector vaccine"@en ; rdfs:subClassOf obo:VO_0005199 , obo:VO_0005264 . obo:OBI_0000011 a rdfs:Class ; rdfs:label "planned process" ; rdfs:comment "A processual entity that realizes a plan which is the concretization of a plan specification."@en ; rdfs:subClassOf obo:BFO_0000015 . obo:HP_0031675 a rdfs:Class ; rdfs:label "Fascicular left ventricular tachycardia" ; rdfs:comment "A ventricular tachycardia (VT) characterized by right bundle branch block (RBBB) and left axis deviation (LAD) on electrocardiogram (ECG)." ; rdfs:subClassOf obo:HP_0004756 . obo:NCBITaxon_903597 a rdfs:Class ; rdfs:label "Kenya bat coronavirus BtKY59" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:PR_Q15818 a rdfs:Class ; rdfs:label "neuronal pentraxin-1 (human)" ; rdfs:comment "A neuronal pentraxin-1 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000011382 , obo:PR_000029067 . obo:NCBITaxon_347536 a rdfs:Class ; rdfs:label "Bat SARS CoV Rm1/2004" ; rdfs:subClassOf obo:NCBITaxon_694009 . a rdfs:Class ; rdfs:label "Pupillary Dilation [PE]" ; rdfs:subClassOf . obo:DRON_00803385 a rdfs:Class ; rdfs:label "abemaciclib" ; rdfs:subClassOf obo:OBI_0000047 . obo:NCBITaxon_903569 a rdfs:Class ; rdfs:label "Kenya bat coronavirus BtKY101" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:HP_0033127 a rdfs:Class ; rdfs:label "Abnormality of the musculoskeletal system" ; rdfs:comment "An anomaly of the musculoskeletal system, which consists of the bones of the skeleton, muscles, cartilage, tendons, ligaments, joints, and other connective tissue. The musculoskeletal system supports the weight of the body, maintains body position and produces movements of the body or of parts of the body." ; rdfs:subClassOf obo:HP_0000118 . obo:DOID_0070080 a rdfs:Class ; rdfs:label "schizophrenia 4" ; rdfs:comment "A schizophrenia that has_material_basis_in an autosomal dominant mutation of PRODH on chromosome 22q11.21." ; rdfs:subClassOf obo:DOID_0050736 , obo:DOID_5419 . obo:PR_Q99870 a rdfs:Class ; rdfs:subClassOf obo:PR_000000001 . obo:NCBITaxon_398815 a rdfs:Class ; rdfs:label "PRCV ISU-1" ; rdfs:subClassOf obo:NCBITaxon_11146 . obo:OPMI_0000512 a rdfs:Class ; rdfs:label "provenance of record"@en ; rdfs:comment "The information content entity that represents the origin of record such as the clinical form as the origin record of death." ; rdfs:subClassOf obo:IAO_0000030 . obo:PR_000032183 a rdfs:Class ; rdfs:label "DnaJ homolog subfamily C member 11" ; rdfs:comment "A protein that is a translation product of the human DNAJC11 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:PR_Q9NU22 a rdfs:Class ; rdfs:label "midasin (human)" ; rdfs:comment "A midasin that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000010269 , obo:PR_000029067 . obo:PR_P09210 a rdfs:Class ; rdfs:label "glutathione S-transferase A2 (human)" ; rdfs:comment "A glutathione S-transferase A2 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000008295 , obo:PR_000029067 . obo:NCBITaxon_1679913 a rdfs:Class ; rdfs:label "Coronavirus RCoV/NSP32/Rha_pum/RSA/2008" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:HP_0011947 a rdfs:Class ; rdfs:label "Respiratory tract infection" ; rdfs:comment "An infection of the upper or lower respiratory tract." ; rdfs:subClassOf obo:HP_0002088 . obo:NCBITaxon_204266 a rdfs:Class ; rdfs:label "Melogale" ; rdfs:subClassOf obo:NCBITaxon_1008261 . obo:PR_000001998 a rdfs:Class ; rdfs:label "C-C motif chemokine 3/4" ; rdfs:comment "A C/C-C motif small inducible chemokine that is a translation product of the CCL3, CCL3L1/CCL3L3, or CCL4 gene." ; rdfs:subClassOf obo:PR_000001808 . obo:CIDO_0020119 a rdfs:Class ; rdfs:label "Dimension Vista SARS‑CoV‑2 IgG (COV2G)" ; rdfs:seeAlso ; rdfs:subClassOf obo:CIDO_0000454 . obo:PR_000014195 a rdfs:Class ; rdfs:label "60S ribosomal protein L15" ; rdfs:comment "A protein that is a translation product of the human RPL15 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . a rdfs:Class ; rdfs:label "Immunologic Factors [MoA]" ; rdfs:subClassOf . obo:CHEBI_63726 a rdfs:Class ; rdfs:label "neuroprotective agent" ; rdfs:comment "Any compound that can be used for the treatment of neurodegenerative disorders." ; rdfs:subClassOf obo:CHEBI_50267 . obo:CHEBI_23824 a rdfs:Class ; rdfs:label "diol" ; rdfs:comment "A compound that contains two hydroxy groups, generally assumed to be, but not necessarily, alcoholic. Aliphatic diols are also called glycols." ; rdfs:subClassOf obo:CHEBI_26191 . obo:BFO_0000008 a rdfs:Class ; rdfs:label "temporal region"@en ; rdfs:subClassOf obo:BFO_0000003 . obo:NCBITaxon_890398 a rdfs:Class ; rdfs:label "Bat coronavirus Hipposideros/KT/Thailand/2007" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:CIDO_0020207 a rdfs:Class ; rdfs:label "MosaiQ COVID-19 Antibody Magazine" ; rdfs:seeAlso ; rdfs:subClassOf obo:CIDO_0000454 . a rdfs:Class ; rdfs:label "Cardiovascular Diseases [Disease/Finding]" ; rdfs:subClassOf . obo:PR_Q14157 a rdfs:Class ; rdfs:label "ubiquitin-associated protein 2-like (human)" ; rdfs:comment "A ubiquitin-associated protein 2-like that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000016960 , obo:PR_000029067 . obo:PR_P05023 a rdfs:Class ; rdfs:label "sodium/potassium-transporting ATPase subunit alpha-1 (human)" ; rdfs:comment "A sodium/potassium-transporting ATPase subunit alpha-1 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000004435 , obo:PR_000029067 . obo:NCBITaxon_681878 a rdfs:Class ; rdfs:label "Kenya bat coronavirus BtKY34" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:CHEBI_50667 a rdfs:Class ; rdfs:label "mercaptopurine" ; rdfs:comment "A purine that has formula C5H4N4S." ; rdfs:subClassOf obo:CHEBI_26401 . obo:NCBITaxon_1699333 a rdfs:Class ; rdfs:label "Myotis Bat Alphacoronavirus strain YNXY_33C" ; rdfs:subClassOf obo:NCBITaxon_366617 . obo:CIDO_0000849 a rdfs:Class ; rdfs:label "SARS-CoV2 nsp13 protein binding to human NIN" ; rdfs:comment "SARS-CoV2 nsp13 protein binding to human NIN, as evidented by an affinity-purification mass spectrometry experiment" ; rdfs:subClassOf obo:CIDO_0000058 . obo:NCBITaxon_231429 a rdfs:Class ; rdfs:label "Turkey coronavirus (strain Indiana)" ; rdfs:subClassOf obo:NCBITaxon_11152 . obo:OBI_0002609 a rdfs:Class ; rdfs:label "rectal swab specimen" ; rdfs:comment "A specimen that is collected with a swab from the surface of a rectum." ; rdfs:subClassOf obo:OBI_0002599 . obo:CHEBI_28157 a rdfs:Class ; rdfs:label "pinocembrin" ; rdfs:comment "A dihydroxyflavanone in which the two hydroxy groups are located at positions 5 and 7. A natural product found in Piper sarmentosum and Cryptocarya chartacea." ; rdfs:subClassOf obo:CHEBI_140377 , obo:CHEBI_38749 . obo:NCBITaxon_389233 a rdfs:Class ; rdfs:label "Bat coronavirus (BtCoV/303/2005)" ; rdfs:subClassOf obo:NCBITaxon_389126 . obo:CHEBI_51177 a rdfs:Class ; rdfs:label "antitussive" ; rdfs:comment "An agent that suppresses cough. Antitussives have a central or a peripheral action on the cough reflex, or a combination of both. Compare with expectorants, which are considered to increase the volume of secretions in the respiratory tract, so facilitating their removal by ciliary action and coughing, and mucolytics, which decrease the viscosity of mucus, facilitating its removal by ciliary action and expectoration." ; rdfs:subClassOf obo:CHEBI_23888 . obo:CHEBI_76895 a rdfs:Class ; rdfs:label "EC 3.6.3.* (acid anhydride hydrolase catalysing transmembrane movement of substances) inhibitor" ; rdfs:comment "An EC 3.6.* (hydrolases acting on acid anhydrides) inhibitor that interferes with the action of any such enzyme that catalyses transmembrane movement of substances (EC 3.6.3.*)." ; rdfs:subClassOf obo:CHEBI_73216 . a rdfs:Class ; rdfs:label "Vulvar Diseases [Disease/Finding]" ; rdfs:subClassOf . obo:CIDO_0000731 a rdfs:Class ; rdfs:label "D253G in SARS-CoV-2 S protein"@en ; rdfs:comment "An AA mutation or AA variant that has mutated an amino acid at position 253 into glycine in S protein." ; rdfs:subClassOf obo:CIDO_0000593 . a rdfs:Class ; rdfs:label "GI Motility Alteration [PE]" ; rdfs:subClassOf . obo:CHEBI_83818 a rdfs:Class ; rdfs:label "morphinane-like compound" ; rdfs:comment "Any organonitrogen heterocyclic compound based on a morphinan skeleton. These are synthetic or semi-synthetic compounds that resemble the morphinane (opioid) alkaloids in their pharmacological effects." ; rdfs:subClassOf obo:CHEBI_38101 . obo:CHEBI_31647 a rdfs:Class ; rdfs:label "gemcitabine hydrochloride" ; rdfs:comment "A 2'-deoxycytidine hydrochloriode having geminal fluoro substituents in the 2'-position. An inhibitor of ribonucleotide reductase, gemcitabine hydrochloride is used in the treatment of various carcinomas, including non-small cell lung cancer, pancreatic cancer, bladder cancer and breast cancer." ; rdfs:subClassOf obo:CHEBI_36807 , obo:CHEBI_37143 . obo:GO_0060191 a rdfs:Class ; rdfs:label "regulation of lipase activity" ; rdfs:comment "Any process that modulates the frequency, rate or extent of lipase activity, the hydrolysis of a lipid or phospholipid." ; rdfs:subClassOf obo:GO_0051336 . obo:CHEBI_76815 a rdfs:Class ; rdfs:label "EC 2.7.7.* (nucleotidyltransferase) inhibitor" ; rdfs:comment "An EC 2.7.* (P-containing group transferase) inhibitor that interferes with the action of any nucleotidyltransferase (EC 2.7.7.*)." ; rdfs:subClassOf obo:CHEBI_76668 . obo:CHEBI_35476 a rdfs:Class ; rdfs:label "antipsychotic agent" ; rdfs:comment "Antipsychotic drugs are agents that control agitated psychotic behaviour, alleviate acute psychotic states, reduce psychotic symptoms, and exert a quieting effect." ; rdfs:subClassOf obo:CHEBI_35473 . obo:CIDO_0020288 a rdfs:Class ; rdfs:label "SDNA-1000 Saliva Collection Device" ; rdfs:seeAlso ; rdfs:subClassOf obo:CIDO_0000455 . obo:CHEBI_32728 a rdfs:Class ; rdfs:label "tryptophanium" ; rdfs:comment "An alpha-amino-acid cation that is the conjugate acid of tryptophan, arising from protonation of the alpha-amino group." ; rdfs:subClassOf obo:CHEBI_33719 . obo:NCBITaxon_1965093 a rdfs:Class ; rdfs:label "Hedgehog coronavirus 1" ; rdfs:subClassOf obo:NCBITaxon_2509494 . obo:OBI_0002510 a rdfs:Class ; rdfs:label "synovial fluid specimen" ; rdfs:comment "A specimen that is derived from synovial fluid." ; rdfs:subClassOf obo:OBI_2000009 . obo:CIDO_0000429 a rdfs:Class ; rdfs:label "MERS diagnosis conclusion"@en ; rdfs:comment "The representation of a conclusion of a diagnostic process for the MERS coronavirus disease." ; rdfs:subClassOf obo:CIDO_0000427 . obo:NCBITaxon_11125 a rdfs:Class ; rdfs:label "Avian infectious bronchitis virus (strain D3896)" ; rdfs:subClassOf obo:NCBITaxon_11120 . obo:NCBITaxon_1679902 a rdfs:Class ; rdfs:label "Coronavirus RCoV/D_RMU10_974/Myo_gla/GER/2010" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:GO_0005244 a rdfs:Class ; rdfs:label "voltage-gated ion channel activity" ; rdfs:comment "Enables the transmembrane transfer of an ion by a voltage-gated channel. An ion is an atom or group of atoms carrying an electric charge by virtue of having gained or lost one or more electrons. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded." ; rdfs:subClassOf obo:GO_0015075 , obo:GO_0022836 . obo:PR_Q99519 a rdfs:Class ; rdfs:label "sialidase-1 (human)" ; rdfs:comment "A sialidase-1 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000011145 , obo:PR_000029067 . obo:CIDO_0000612 a rdfs:Class ; rdfs:label "G142D in SARS-CoV-2 S protein"@en ; rdfs:comment "An AA mutation or AA variant that has mutated an amino acid at position 142 into a aspartic acid in S protein." ; rdfs:subClassOf obo:CIDO_0000594 . obo:PR_Q9UBX5 a rdfs:Class ; rdfs:label "fibulin-5 (human)" ; rdfs:comment "A fibulin-5 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000007360 , obo:PR_000029067 . obo:CIDO_0000379 a rdfs:Class ; rdfs:label "SARS-CoV-2 Zeta variant"@en ; rdfs:subClassOf obo:CIDO_0000407 . obo:CIDO_0000100 a rdfs:Class ; rdfs:label "interruption to SARS-CoV infection"@en ; rdfs:comment "A process that interrupts SARS-CoV viral infection in host" ; rdfs:subClassOf obo:CIDO_0000098 . obo:PR_000004650 a rdfs:Class ; rdfs:label "protein BAT2-like" ; rdfs:comment "A protein that is a translation product of the human PRRC2B gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:CIDO_0001208 a rdfs:Class ; rdfs:label "Multiple Real-Time PCR Kit for Detection of 2019-nCoV. (Shanghai Geneodx BIOTECH Company Limited)" ; rdfs:comment "Scope of application/Intended use: This kit is used for in vitro qualitative detection of novel coronavirus (2019 -nCoV) ORF1ab and N genes." ; rdfs:subClassOf obo:CIDO_0000021 . obo:PR_P52333 a rdfs:Class ; rdfs:label "tyrosine-protein kinase JAK3 (human)" ; rdfs:comment "A tyrosine-protein kinase JAK3 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000009198 , obo:PR_000029067 . obo:CIDO_0020333 a rdfs:Class ; rdfs:label "Wantai SARS-CoV-2 RT-PCR Kit" ; rdfs:seeAlso ; rdfs:subClassOf obo:CIDO_0000454 . obo:VO_0005238 a rdfs:Class ; rdfs:label "VBI-2902a"@en ; rdfs:comment "A SARS-CoV-2 virus-like particle vaccine that expresses a modified version of the SARS-CoV-2 spike (S) glycoprotein and is equipped with an aluminum phosphate adjuvant. It is manufactured by VBI Vaccines Inc. and is delivered intramuscularly." ; rdfs:subClassOf obo:VO_0005205 . obo:PR_P0DTC9 a rdfs:Class ; rdfs:label "nucleoprotein (SARS-CoV-2)" ; rdfs:comment "A protein that is a translation product of the N gene in SARS-CoV-2." ; rdfs:subClassOf obo:PR_000050262 , obo:PR_P0DTC9-1 . obo:CIDO_0020296 a rdfs:Class ; rdfs:label "SNL-NM 2019 nCoV Real-Time RT-PCR Diagnostic Assay" ; rdfs:seeAlso ; rdfs:subClassOf obo:CIDO_0000454 . obo:NCBITaxon_1496612 a rdfs:Class ; rdfs:label "Betacoronavirus JMH-2014" ; rdfs:subClassOf obo:NCBITaxon_696098 . obo:NCBITaxon_627433 a rdfs:Class ; rdfs:label "Feline coronavirus UU15" ; rdfs:subClassOf obo:NCBITaxon_12663 . obo:CHEBI_73181 a rdfs:Class ; rdfs:label "EC 1.11.1.11 (L-ascorbate peroxidase) inhibitor" ; rdfs:comment "An EC 1.11.1.* (peroxidases) inhibitor that inhibits the action of L-ascorbate peroxidase (EC 1.11.1.11)." ; rdfs:subClassOf obo:CHEBI_75381 . obo:VO_0005319 a rdfs:Class ; rdfs:label "AZD2816"@en ; rdfs:comment "A SARS-CoV-2 recombinant vector vaccine by AstraZeneca and Oxford University against variant strain B.1.351" ; rdfs:subClassOf obo:VO_0005199 . obo:PR_000044671 a rdfs:Class ; rdfs:label "ligand-gated ion channel protein" ; rdfs:comment "An ion channel protein that has ligand-gated ion channel activity. The ligand-gated ion channel opens when a specific ligand has been bound by the channel complex or one of its constituent parts." ; rdfs:subClassOf obo:PR_000049983 . obo:PR_000001183 a rdfs:Class ; rdfs:label "alpha-1A adrenergic receptor" ; rdfs:comment "An alpha-1 adrenergic receptor that is a translation product of the human ADRA1A gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000001115 . obo:NCBITaxon_2509512 a rdfs:Class ; rdfs:label "Setracovirus" ; rdfs:subClassOf obo:NCBITaxon_693996 . obo:GO_0009605 a rdfs:Class ; rdfs:label "response to external stimulus" ; rdfs:comment "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an external stimulus." ; rdfs:subClassOf obo:GO_0050896 . obo:DOID_10914 a rdfs:Class ; rdfs:label "amnestic disorder" ; rdfs:comment "A cognitive disorder where the memory is disturbed or lost and involves the loss of memories previously established, loss of the ability to create new memories, or loss of the ability to learn new information." ; rdfs:subClassOf obo:DOID_1561 . obo:HP_0001881 a rdfs:Class ; rdfs:label "Abnormal leukocyte morphology" ; rdfs:comment "An abnormality of leukocytes." ; rdfs:subClassOf obo:HP_0001871 , obo:HP_0002715 . obo:CHEBI_77746 a rdfs:Class ; rdfs:label "human metabolite" ; rdfs:comment "Any mammalian metabolite produced during a metabolic reaction in humans (Homo sapiens)." ; rdfs:subClassOf obo:CHEBI_75768 . obo:CHEBI_47804 a rdfs:Class ; rdfs:label "dibenzoazepine" ; rdfs:subClassOf obo:CHEBI_26979 , obo:CHEBI_38101 . obo:NCBITaxon_622716 a rdfs:Class ; rdfs:label "Bat coronavirus Hipposideros/GhanaKwam/27/2008" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:CIDO_0001053 a rdfs:Class ; rdfs:label "SARS-CoV2 orf9c protein binding to human GHITM" ; rdfs:comment "SARS-CoV2 orf9c protein binding to human GHITM, as evidented by an affinity-purification mass spectrometry experiment" ; rdfs:subClassOf obo:CIDO_0000054 . obo:CIDO_0000909 a rdfs:Class ; rdfs:label "SARS-CoV2 nsp7 protein binding to human RAB10" ; rdfs:comment "SARS-CoV2 nsp7 protein binding to human RAB10, as evidented by an affinity-purification mass spectrometry experiment" ; rdfs:subClassOf obo:CIDO_0000049 . obo:OBI_0002535 a rdfs:Class ; rdfs:label "esophagus muscularis mucosa specimen" ; rdfs:comment "A specimen that is derived from esophagus muscularis mucosa." ; rdfs:subClassOf obo:OBI_0001479 . obo:GO_0006412 a rdfs:Class ; rdfs:label "translation" ; rdfs:comment "The cellular metabolic process in which a protein is formed, using the sequence of a mature mRNA or circRNA molecule to specify the sequence of amino acids in a polypeptide chain. Translation is mediated by the ribosome, and begins with the formation of a ternary complex between aminoacylated initiator methionine tRNA, GTP, and initiation factor 2, which subsequently associates with the small subunit of the ribosome and an mRNA or circRNA. Translation ends with the release of a polypeptide chain from the ribosome." ; rdfs:subClassOf obo:GO_0034645 , obo:GO_0043043 , obo:GO_0044267 . obo:NCBITaxon_2042580 a rdfs:Class ; rdfs:label "Coronavirus PREDICT CoV-56" ; rdfs:subClassOf obo:NCBITaxon_696098 . a rdfs:Class ; rdfs:label "Decreased Ovarian Estrogen Secretion [PE]" ; rdfs:subClassOf . obo:CHEBI_32879 a rdfs:Class ; rdfs:label "propane" ; rdfs:subClassOf obo:CHEBI_138675 , obo:CHEBI_18310 . obo:NCBITaxon_202496 a rdfs:Class ; rdfs:label "Equine coronavirus NC99" ; rdfs:subClassOf obo:NCBITaxon_136187 . obo:NCBITaxon_681867 a rdfs:Class ; rdfs:label "Kenya bat coronavirus BtKY21" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:NCBITaxon_1235421 a rdfs:Class ; rdfs:label "Alphacoronavirus Perimyotis subflavus" ; rdfs:subClassOf obo:NCBITaxon_366617 . obo:VO_0005332 a rdfs:Class ; rdfs:label "ARCT-165"@en ; rdfs:comment "A SARS-CoV-2 RNA vaccine by Arcturus Therapeutics, Inc." ; rdfs:subClassOf obo:VO_0005198 . obo:PR_Q5S007 a rdfs:Class ; rdfs:label "leucine-rich repeat serine/threonine-protein kinase 2 (human)" ; rdfs:comment "A leucine-rich repeat serine/threonine-protein kinase 2 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000003033 , obo:PR_000029067 . obo:CHEBI_33721 a rdfs:Class ; rdfs:label "carbohydrate acid anion" ; rdfs:subClassOf obo:CHEBI_29067 . obo:CHEBI_33664 a rdfs:Class ; rdfs:label "monocyclic hydrocarbon" ; rdfs:subClassOf obo:CHEBI_33663 . obo:NCBITaxon_931895 a rdfs:Class ; rdfs:label "Alphacoronavirus Eptesicus fuscus/Appalachian Ridge/P3-C450/IT/USA/2009" ; rdfs:subClassOf obo:NCBITaxon_366617 . obo:HP_0011699 a rdfs:Class ; rdfs:label "Atrial reentry tachycardia" ; rdfs:subClassOf obo:HP_0001692 . obo:CHEBI_82680 a rdfs:Class ; rdfs:label "monounsaturated fatty acid anion" ; rdfs:comment "Any unsaturated fatty acid anion with one double or triple bond in the fatty acid chain." ; rdfs:subClassOf obo:CHEBI_2580 . obo:CIDO_0000383 a rdfs:Class ; rdfs:label "SARS-CoV-2 Kappa variant"@en ; rdfs:subClassOf obo:CIDO_0000407 . obo:PR_Q9UHI8 a rdfs:Class ; rdfs:label "a disintegrin and metalloproteinase with thrombospondin motifs 1 (human)" ; rdfs:comment "An a disintegrin and metalloproteinase with thrombospondin motifs 1 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000003727 , obo:PR_000029067 . obo:PR_O75460 a rdfs:Class ; rdfs:label "serine/threonine-protein kinase/endoribonuclease IRE1 (human)" ; rdfs:comment "A serine/threonine-protein kinase/endoribonuclease IRE1 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000007185 , obo:PR_000029067 . obo:NCBITaxon_1429858 a rdfs:Class ; rdfs:label "Betacoronavirus Pipistrellus kuhlii/Italy/206645-3/2011" ; rdfs:subClassOf obo:NCBITaxon_696098 . obo:OAE_0000366 a rdfs:Class ; rdfs:label "injection-site AE" ; rdfs:comment "injection-site AE is an AE that occurs in an injection site (e.g., during vaccination)." ; rdfs:subClassOf obo:OAE_0000226 , obo:OAE_0002625 . a rdfs:Class ; rdfs:label "Paraproteinemias [Disease/Finding]" ; rdfs:subClassOf , . a rdfs:Class ; rdfs:label "Oxyclozanide [Chemical/Ingredient]" ; rdfs:subClassOf . obo:CIDO_0000712 a rdfs:Class ; rdfs:label "Q777H in SARS-CoV-2 S protein"@en ; rdfs:comment "An AA mutation or AA variant that has mutated an amino acid at position 777 into a histidine in S protein." ; rdfs:subClassOf obo:CIDO_0000592 . obo:IAO_0000033 a rdfs:Class ; rdfs:label "directive information entity"@en ; rdfs:comment "An information content entity whose concretizations indicate to their bearer how to realize them in a process."@en ; rdfs:subClassOf obo:IAO_0000030 . obo:DRON_00023504 a rdfs:Class ; rdfs:label "Tamoxifen Oral Tablet" ; rdfs:subClassOf obo:DRON_00000022 . a rdfs:Class ; rdfs:label "Cerebrovascular Disorders [Disease/Finding]" ; rdfs:subClassOf , . obo:GO_0006661 a rdfs:Class ; rdfs:label "phosphatidylinositol biosynthetic process" ; rdfs:comment "The chemical reactions and pathways resulting in the formation of phosphatidylinositol, any glycophospholipid in which the sn-glycerol 3-phosphate residue is esterified to the 1-hydroxyl group of 1D-myo-inositol." ; rdfs:subClassOf obo:GO_0046474 , obo:GO_0046488 . obo:NCBITaxon_2042541 a rdfs:Class ; rdfs:label "Coronavirus PREDICT CoV-14" ; rdfs:subClassOf obo:NCBITaxon_366617 . obo:CHEBI_145947 a rdfs:Class ; rdfs:label "antiatherosclerotic agent" ; rdfs:comment "A cardiovascular drug that prevents atherosclerosis (a disease in which the inside of an artery narrows due to the build up of plaque). Compare with antiatherogenic agent." ; rdfs:subClassOf obo:CHEBI_35554 . obo:HP_0012638 a rdfs:Class ; rdfs:label "Abnormal nervous system physiology" ; rdfs:comment "A functional anomaly of the nervous system." ; rdfs:subClassOf obo:HP_0000707 . obo:BFO_0000002 a rdfs:Class ; rdfs:label "continuant" ; rdfs:comment "An entity that exists in full at any time in which it exists at all, persists through time while maintaining its identity and has no temporal parts."@en ; rdfs:subClassOf obo:BFO_0000001 . obo:CHEBI_33248 a rdfs:Class ; rdfs:label "hydrocarbyl group" ; rdfs:comment "A univalent group formed by removing a hydrogen atom from a hydrocarbon." ; rdfs:subClassOf obo:CHEBI_33249 . obo:NCBITaxon_1788416 a rdfs:Class ; rdfs:label "Bat coronavirus MsBtCoV/4001-2" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:CHEBI_31011 a rdfs:Class ; rdfs:label "valerate" ; rdfs:comment "A short-chain fatty acid anion that is the conjugate base of valeric acid; present in ester form as component of many steroid-based pharmaceuticals." ; rdfs:subClassOf obo:CHEBI_58951 , obo:CHEBI_58954 . obo:CHEBI_32565 a rdfs:Class ; rdfs:label "lysinium(2+)" ; rdfs:comment "An alpha-amino-acid cation obtained by protonation of both amino groups of lysine." ; rdfs:subClassOf obo:CHEBI_33719 . obo:PR_000006582 a rdfs:Class ; rdfs:label "mitochondrial import inner membrane translocase subunit TIM14" ; rdfs:comment "A protein that is a translation product of the human DNAJC19 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:CHEBI_73216 a rdfs:Class ; rdfs:label "EC 3.6.* (hydrolases acting on acid anhydrides) inhibitor" ; rdfs:comment "Any hydrolase inhibitor that interferes with the action of a hydrolase which acts on acid anhydrides (EC 3.6.*.*)." ; rdfs:subClassOf obo:CHEBI_76759 . obo:CIDO_0000515 a rdfs:Class ; rdfs:label "SVVEVVTTSLTPCGY" ; rdfs:comment "A coronavirus epitope that is part of some S protein from HCoV OC43 composed of the following amino acids SVVEVVTTSLTPCGY" ; rdfs:subClassOf obo:CIDO_0000452 . a rdfs:Class ; rdfs:label "Cardiomyopathies [Disease/Finding]" ; rdfs:subClassOf . obo:CIDO_0000808 a rdfs:Class ; rdfs:label "SARS-CoV2 nsp12 protein binding to human PDZD11" ; rdfs:comment "SARS-CoV2 nsp12 protein binding to human PDZD11, as evidented by an affinity-purification mass spectrometry experiment" ; rdfs:subClassOf obo:CIDO_0000057 . obo:NCBITaxon_389158 a rdfs:Class ; rdfs:label "Bat coronavirus (BtCoV/A909/2005)" ; rdfs:subClassOf obo:NCBITaxon_389126 . obo:CIDO_0000212 a rdfs:Class ; rdfs:label "coronaviral structural protein synthesis"@en ; rdfs:comment "A coronavirus molecular interaction that results in the synthesis of viral structure protein" ; rdfs:subClassOf obo:CIDO_0000204 . obo:CIDO_0020020 a rdfs:Class ; rdfs:label "Alpha Genomix TaqPath SARS-CoV-2 Combo Assay" ; rdfs:seeAlso ; rdfs:subClassOf obo:CIDO_0000454 . obo:PR_Q9Y399 a rdfs:Class ; rdfs:label "28S ribosomal protein S2, mitochondrial (human)" ; rdfs:comment "A 28S ribosomal protein S2, mitochondrial that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000010628 , obo:PR_000029067 . obo:NCBITaxon_9666 a rdfs:Class ; rdfs:label "Mustela lutreola" ; rdfs:subClassOf obo:NCBITaxon_9665 . obo:HP_0001259 a rdfs:Class ; rdfs:label "Coma" ; rdfs:comment "Complete absence of wakefulness and content of conscience, which manifests itself as a lack of response to any kind of external stimuli." ; rdfs:subClassOf obo:HP_0004372 . obo:VO_0004990 a rdfs:Class ; rdfs:label "E protein of SARS-CoV-2"@en ; rdfs:subClassOf obo:VO_0004988 . obo:CIDO_0000861 a rdfs:Class ; rdfs:label "SARS-CoV2 nsp13 protein binding to human TLE5" ; rdfs:comment "SARS-CoV2 nsp13 protein binding to human TLE5, as evidented by an affinity-purification mass spectrometry experiment" ; rdfs:subClassOf obo:CIDO_0000058 . obo:NCBITaxon_31628 a rdfs:Class ; rdfs:label "Avian infectious bronchitis virus (strain UK/167/84)" ; rdfs:subClassOf obo:NCBITaxon_11120 . obo:PR_Q9H270 a rdfs:Class ; rdfs:label "vacuolar protein sorting-associated protein 11 homolog (human)" ; rdfs:comment "A vacuolar protein sorting-associated protein 11 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000017318 , obo:PR_000029067 . obo:CHEBI_55324 a rdfs:Class ; rdfs:label "gastrointestinal drug" ; rdfs:comment "A drug used for its effects on the gastrointestinal system, e.g. controlling gastric acidity, regulating gastrointestinal motility and water flow, and improving digestion." ; rdfs:subClassOf obo:CHEBI_23888 . obo:CHEBI_94484 a rdfs:Class ; rdfs:label "1-phenyl-1-cyclopentanecarboxylic acid 2-[2-(diethylamino)ethoxy]ethyl ester" ; rdfs:subClassOf obo:CHEBI_22712 . obo:CHEBI_51598 a rdfs:Class ; rdfs:label "diaminopyridine" ; rdfs:comment "Compounds containing a pyridine skeleton substituted by two amino groups." ; rdfs:subClassOf obo:CHEBI_38207 . a rdfs:Class ; rdfs:label "Bicyclo Compounds [Chemical/Ingredient]" ; rdfs:subClassOf . obo:CHEBI_36357 a rdfs:Class ; rdfs:label "polyatomic entity" ; rdfs:comment "Any molecular entity consisting of more than one atom." ; rdfs:subClassOf obo:CHEBI_23367 . obo:CIDO_0020305 a rdfs:Class ; rdfs:label "TBG SARS-CoV-2 IgG / IgM Rapid Test Kit" ; rdfs:seeAlso ; rdfs:subClassOf obo:CIDO_0000454 . obo:CHEBI_33559 a rdfs:Class ; rdfs:label "s-block element atom" ; rdfs:subClassOf obo:CHEBI_33250 . obo:GO_0022843 a rdfs:Class ; rdfs:label "voltage-gated cation channel activity" ; rdfs:comment "Enables the transmembrane transfer of a cation by a voltage-gated channel. A cation is a positively charged ion. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded." ; rdfs:subClassOf obo:GO_0005244 , obo:GO_0005261 . obo:CHEBI_88188 a rdfs:Class ; rdfs:label "drug allergen" ; rdfs:comment "Any drug which causes the onset of an allergic reaction." ; rdfs:subClassOf obo:CHEBI_23888 , obo:CHEBI_50904 . obo:PR_Q9H0K1 a rdfs:Class ; rdfs:label "serine/threonine-protein kinase SIK2 (human)" ; rdfs:comment "A serine/threonine-protein kinase SIK2 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000014871 , obo:PR_000029067 . obo:NCBITaxon_864615 a rdfs:Class ; rdfs:label "Bat coronavirus BR98-40/BGR/2008" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:UBERON_0001986 a rdfs:Class ; rdfs:label "endothelium" ; rdfs:comment "A layer of epithelium that lines the heart, blood vessels (endothelium, vascular), lymph vessels (endothelium, lymphatic), and the serous cavities of the body[MESH]. Simple squamous epithelium which lines blood and lymphatic vessels and the heart[FMA]" ; rdfs:subClassOf obo:UBERON_0000483 , obo:UBERON_0012275 . obo:CIDO_0001223 a rdfs:Class ; rdfs:label "SARS-CoV-2 Nucleic Acid Detection Kit (Integrated Isothermal Amplification Chip Method) (Chengdu Capitalbio Jinxin Bio-Technology Co., Ltd.)" ; rdfs:comment "Poduct storage conditions and expiration date: The kit includes two parts, A and B. Part A is stored at 2~8℃ in the dark, and part B is stored at -20±5℃. The validity period is tentatively set for 6 months." ; rdfs:subClassOf obo:CIDO_0000021 . obo:CIDO_0000824 a rdfs:Class ; rdfs:label "SARS-CoV2 nsp13 protein binding to human C1orf50" ; rdfs:comment "SARS-CoV2 nsp13 protein binding to human C1orf50, as evidented by an affinity-purification mass spectrometry experiment" ; rdfs:subClassOf obo:CIDO_0000058 . obo:CIDO_0000640 a rdfs:Class ; rdfs:label "K856R in SARS-CoV-2 pp1a protein" ; rdfs:comment "An AA mutation or AA variant that has mutated an amino acid at position 856 into a arginine in pp1a." ; rdfs:subClassOf obo:CIDO_0001074 . obo:CIDO_0000500 a rdfs:Class ; rdfs:label "QAISSSIQAIYDRLD" ; rdfs:comment "A coronavirus epitope that is part of some S protein from HCoV 229E composed of the following amino acids QAISSSIQAIYDRLD" ; rdfs:subClassOf obo:CIDO_0000451 . obo:CHEBI_32862 a rdfs:Class ; rdfs:label "L-prolinate" ; rdfs:comment "An optically active form of prolinate having L-configuration." ; rdfs:subClassOf obo:CHEBI_32871 , obo:CHEBI_59814 . obo:CIDO_0020031 a rdfs:Class ; rdfs:label "Aspirus SARS-CoV-2 rRT Assay" ; rdfs:seeAlso ; rdfs:subClassOf obo:CIDO_0000454 . obo:NCBITaxon_1346296 a rdfs:Class ; rdfs:label "Betacoronavirus BtCoV/Rhi_bla/BB98-22/BGR/2008" ; rdfs:subClassOf obo:NCBITaxon_696098 . obo:CHEBI_27266 a rdfs:Class ; rdfs:label "valine" ; rdfs:comment "A branched-chain amino acid that consists of glycine in which one of the hydrogens attached to the alpha-carbon is substituted by an isopropyl group." ; rdfs:subClassOf obo:CHEBI_22918 , obo:CHEBI_33704 . obo:CHEBI_24632 a rdfs:Class ; rdfs:label "hydrocarbon" ; rdfs:comment "A compound consisting of carbon and hydrogen only." ; rdfs:subClassOf obo:CHEBI_33245 . obo:CIDO_0000320 a rdfs:Class ; rdfs:label "FTVEKGIYQTSNFRV"@en ; rdfs:subClassOf obo:CIDO_0000314 . obo:CHEBI_23643 a rdfs:Class ; rdfs:label "depsipeptide" ; rdfs:comment "A natural or synthetic compound having a sequence of amino and hydroxy carboxylic acid residues (usually alpha-amino and alpha-hydroxy acids), commonly but not necessarily regularly alternating." ; rdfs:subClassOf obo:CHEBI_16670 . obo:CHEBI_38655 a rdfs:Class ; rdfs:label "(S)-2-methylbutyric acid" ; rdfs:comment "The (S)-enantiomer of 2-methylbutanoic acid." ; rdfs:subClassOf obo:CHEBI_37070 . obo:PR_000003842 a rdfs:Class ; rdfs:label "alkyldihydroxyacetonephosphate synthase, peroxisomal" ; rdfs:comment "A protein that is a translation product of the human AGPS gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:UBERON_0000007 a rdfs:Class ; rdfs:label "pituitary gland" ; rdfs:comment "The pituitary gland is an endocrine gland that secretes hormones that regulate many other glands [GO]. An endocrine gland located ventral to the diencephalon and derived from mixed neuroectodermal and non neuroectodermal origin [ZFIN]." ; rdfs:subClassOf obo:UBERON_0000465 . obo:OBI_0002604 a rdfs:Class ; rdfs:label "breast swab specimen" ; rdfs:comment "A specimen that is collected with a swab from the surface of a breast." ; rdfs:subClassOf obo:OBI_0002599 . obo:CHEBI_63594 a rdfs:Class ; rdfs:label "1-ribosyltriazole" ; rdfs:comment "A 1-glycosyltriazole in which the glycosyl residue is specified as ribosyl." ; rdfs:subClassOf obo:CHEBI_63593 . obo:PR_000013056 a rdfs:Class ; rdfs:label "peroxisome proliferator-activated receptor alpha" ; rdfs:comment "A protein that is a translation product of the human PPARA gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:CHEBI_83811 a rdfs:Class ; rdfs:label "proteinogenic amino acid derivative" ; rdfs:comment "Any derivative of a proteinogenic amino acid resulting from reaction at an amino group, carboxy group, or a side-chain functional group, or from the replacement of any hydrogen by a heteroatom." ; rdfs:subClassOf obo:CHEBI_83821 . obo:PR_000001030 a rdfs:Class ; rdfs:label "erm protein" ; rdfs:comment "A protein that contain 3 domains, an N-terminal globular domain, an extended alpha-helical domain, and a charged C-terminal domain. Ezrin, radixin and merlin also contain a polyproline region between the helical and C-terminal domains. The N-terminal domain is highly conserved, and is also found in merlin, band 4.1 proteins and members of the band 4.1 superfamily. ERM proteins are involved in crosslinking actin filaments with plasma membranes." ; rdfs:subClassOf obo:PR_000000001 . obo:CHEBI_37578 a rdfs:Class ; rdfs:label "halide" ; rdfs:comment "Any heteroatomic molecular entity that is a chemical compound of halogen with other chemical elements." ; rdfs:subClassOf obo:CHEBI_24471 , obo:CHEBI_37577 . obo:CHEBI_6078 a rdfs:Class ; rdfs:label "Ivermectin" ; rdfs:comment "A mixture consisting of >= 90% 22,23-dihydroavermectin B1a (R = Me) and <= 10% 22,23-dihydroavermectin B1b (R = H). A semi-synthetic derivative of abamectin, it is used as a broad-spectrum antiparasite medication, particularly against worms (except tapeworms), although it is also effective against most mites and some lice." ; rdfs:subClassOf obo:CHEBI_60004 . obo:CIDO_0000573 a rdfs:Class ; rdfs:label "MLHGGGVAKAIAVAA" ; rdfs:comment "A coronavirus epitope that is part of some S protein from HCoV HKU1 composed of the following amino acids MLHGGGVAKAIAVAA" ; rdfs:subClassOf obo:CIDO_0000450 . obo:CHEBI_64775 a rdfs:Class ; rdfs:label "organic anionic group" ; rdfs:comment "An anionic group that contains carbon." ; rdfs:subClassOf obo:CHEBI_64767 . obo:CHEBI_28121 a rdfs:Class ; rdfs:label "harmine" ; rdfs:comment "A harmala alkaloid in which the harman skeleton is methoxy-substituted at C-7." ; rdfs:subClassOf obo:CHEBI_61379 . obo:NCBITaxon_249074 a rdfs:Class ; rdfs:label "SARS coronavirus HZS2-D" ; rdfs:subClassOf obo:NCBITaxon_694009 . obo:PR_000010163 a rdfs:Class ; rdfs:label "mitogen-activated protein kinase 9" ; rdfs:comment "A protein that is a translation product of the human MAPK9 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:NCBITaxon_441619 a rdfs:Class ; rdfs:label "Canine coronavirus BGF10" ; rdfs:subClassOf obo:NCBITaxon_11153 . obo:CHEBI_35987 a rdfs:Class ; rdfs:label "diamino acid" ; rdfs:comment "Any amino acid carrying two amino groups." ; rdfs:subClassOf obo:CHEBI_33709 . obo:NCBITaxon_249081 a rdfs:Class ; rdfs:label "SARS coronavirus ZS-B" ; rdfs:subClassOf obo:NCBITaxon_694009 . obo:CIDO_0000072 a rdfs:Class ; rdfs:label "chemical role against coronaviral replication"@en ; rdfs:subClassOf obo:CIDO_0000068 . obo:CIDO_0000697 a rdfs:Class ; rdfs:label "T1027I in SARS-CoV-2 S protein" ; rdfs:comment "An AA mutation or AA variant that has mutated an amino acid at position 1027 into a isoleucine in S protein." ; rdfs:subClassOf obo:CIDO_0001162 . obo:NCBITaxon_1269316 a rdfs:Class ; rdfs:label "Coronavirus BtCoV/KP816/Phy_dis/PAN/2011" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:GO_0008542 a rdfs:Class ; rdfs:label "visual learning" ; rdfs:comment "Any process in an organism in which a change in behavior of an individual occurs in response to repeated exposure to a visual cue." ; rdfs:subClassOf obo:GO_0007611 , obo:GO_0007632 . obo:NCBITaxon_1403205 a rdfs:Class ; rdfs:label "Coronavirus PgCoV-3" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:CIDO_0020110 a rdfs:Class ; rdfs:label "Cuur Diagnostics SARS-CoV-2 Molecular Assay" ; rdfs:seeAlso ; rdfs:subClassOf obo:CIDO_0000454 . obo:CHEBI_85251 a rdfs:Class ; rdfs:label "teicoplanin A2-2" ; rdfs:comment "A teicoplanin A2 that has 8-methylnonanoyl as the variable N-acyl group." ; rdfs:subClassOf obo:CHEBI_34994 . obo:NCBITaxon_1788424 a rdfs:Class ; rdfs:label "Bat coronavirus MfusBtCoV/4023-2" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:CIDO_0001068 a rdfs:Class ; rdfs:label "SARS-CoV2 orf9c protein binding to human UBXN8" ; rdfs:comment "SARS-CoV2 orf9c protein binding to human UBXN8, as evidented by an affinity-purification mass spectrometry experiment" ; rdfs:subClassOf obo:CIDO_0000054 . obo:PR_000003945 a rdfs:Class ; rdfs:label "dolichyl-phosphate beta-glucosyltransferase" ; rdfs:comment "A protein that is a translation product of the human ALG5 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . a rdfs:Class ; rdfs:label "Dopamine Activity Alteration [PE]" ; rdfs:subClassOf . obo:NCBITaxon_1934040 a rdfs:Class ; rdfs:label "Anser cygnoides coronavirus" ; rdfs:subClassOf obo:NCBITaxon_1232736 . obo:PR_P54219 a rdfs:Class ; rdfs:label "chromaffin granule amine transporter (human)" ; rdfs:comment "A chromaffin granule amine transporter that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000014966 , obo:PR_000029067 . obo:OBI_0000953 a rdfs:Class ; rdfs:label "processed specimen" ; rdfs:comment "A specimen that has been intentionally physically modified." ; rdfs:subClassOf obo:OBI_0000047 , obo:OBI_0100051 . obo:CHEBI_29256 a rdfs:Class ; rdfs:label "thiol" ; rdfs:comment "An organosulfur compound in which a thiol group, -SH, is attached to a carbon atom of any aliphatic or aromatic moiety." ; rdfs:subClassOf obo:CHEBI_33261 . obo:PR_P13804 a rdfs:Class ; rdfs:label "electron transfer flavoprotein subunit alpha, mitochondrial (human)" ; rdfs:comment "An electron transfer flavoprotein subunit alpha, mitochondrial that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000007215 , obo:PR_000029067 . obo:NCBITaxon_1586324 a rdfs:Class ; rdfs:label "Porcine deltacoronavirus" ; rdfs:subClassOf obo:NCBITaxon_1159905 . obo:NCBITaxon_864598 a rdfs:Class ; rdfs:label "Bat coronavirus BM48-34/BGR/2008" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:NCBITaxon_422139 a rdfs:Class ; rdfs:label "Giraffe coronavirus US/OH3/2003" ; rdfs:subClassOf obo:NCBITaxon_11128 . a rdfs:Class ; rdfs:label "CLOMIPRAMINE HYDROCHLORIDE" ; rdfs:subClassOf . obo:CHEBI_59202 a rdfs:Class ; rdfs:label "straight-chain fatty acid" ; rdfs:comment "Any fatty acid whose skeletal carbon atoms form an unbranched open chain." ; rdfs:subClassOf obo:CHEBI_35366 . obo:NCBITaxon_1381364 a rdfs:Class ; rdfs:label "Bat coronavirus Rhhar/CII_KSA_003/Bisha/Saudi Arabia/2013" ; rdfs:subClassOf obo:NCBITaxon_366617 . a rdfs:Class ; rdfs:label "Carcinoma, Ductal [Disease/Finding]" ; rdfs:subClassOf , . obo:DOID_593 a rdfs:Class ; rdfs:label "agoraphobia" ; rdfs:comment "A phobic disorder involving the specific anxiety about being in a place or situation where escape is difficult or embarrassing or where help may be unavailable." ; rdfs:subClassOf obo:DOID_591 . obo:CHEBI_50018 a rdfs:Class ; rdfs:label "glycosyloxyflavone" ; rdfs:comment "A member of the class of flavones having one or more glycosyl residues attached at unspecified positions." ; rdfs:subClassOf obo:CHEBI_24043 , obo:CHEBI_24400 . a rdfs:Class ; rdfs:label "Pyrimidinones [Chemical/Ingredient]" ; rdfs:subClassOf . obo:NCBITaxon_2042568 a rdfs:Class ; rdfs:label "Coronavirus PREDICT CoV-42" ; rdfs:subClassOf obo:NCBITaxon_366617 . obo:PR_000001612 a rdfs:Class ; rdfs:label "mu-type opioid receptor" ; rdfs:comment "An opioid receptor protein that is a translation product of the human OPRM1 gene or a 1:1 ortholog thereof. The preferred ligands are beta-endorphin and enkephalins." ; rdfs:subClassOf obo:PR_000001497 . obo:HP_0001888 a rdfs:Class ; rdfs:label "Lymphopenia" ; rdfs:comment "A reduced number of lymphocytes in the blood." ; rdfs:subClassOf obo:HP_0011893 , obo:HP_0040088 . obo:NCBITaxon_1244203 a rdfs:Class ; rdfs:label "Bat coronavirus HKU10" ; rdfs:subClassOf obo:NCBITaxon_2509479 . obo:PR_000014476 a rdfs:Class ; rdfs:label "protein strawberry notch homolog 1" ; rdfs:comment "A protein that is a translation product of the human SBNO1 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:NCBITaxon_389145 a rdfs:Class ; rdfs:label "Bat coronavirus Fujian/773/2005" ; rdfs:subClassOf obo:NCBITaxon_366617 . obo:CHEBI_15966 a rdfs:Class ; rdfs:label "D-glutamic acid" ; rdfs:comment "An optically active form of glutamic acid having D-configuration." ; rdfs:subClassOf obo:CHEBI_16733 , obo:CHEBI_18237 . a rdfs:Class ; rdfs:label "Immune System Diseases [Disease/Finding]" ; rdfs:subClassOf . obo:PR_Q6UW63 a rdfs:Class ; rdfs:label "protein O-glucosyltransferase 2 (human)" ; rdfs:comment "A protein O-glucosyltransferase 2 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000029067 , obo:PR_000031874 . obo:CIDO_0000039 a rdfs:Class ; rdfs:label "COVID-19 diagnostic process using LAMP assay"@en ; rdfs:comment "A COVID-19 diagnostic process that detects SARS-CoV-2 by loop mediated isothermal amplification (LAMP) assay" ; rdfs:subClassOf obo:CIDO_0000038 . obo:NCBITaxon_1284372 a rdfs:Class ; rdfs:label "Bat coronavirus BtCoV/8-691/Pip_nat/ROU/2009" ; rdfs:subClassOf obo:NCBITaxon_696098 . obo:CIDO_0000368 a rdfs:Class ; rdfs:label "N95 Respirator"@en ; rdfs:comment "A respirator designed to protect the user from breathing in contaminants in the air, thus preserving the health of their respiratory tract." ; rdfs:subClassOf obo:CIDO_0000367 . obo:CHEBI_33727 a rdfs:Class ; rdfs:label "proteinogenic amino-acid residue cation" ; rdfs:subClassOf obo:CHEBI_33700 , obo:CHEBI_35415 . obo:CIDO_0000774 a rdfs:Class ; rdfs:label "SARS-CoV2 M protein binding to human TUBGCP3" ; rdfs:comment "SARS-CoV2 M protein binding to human TUBGCP3, as evidented by an affinity-purification mass spectrometry experiment" ; rdfs:subClassOf obo:CIDO_0000055 . obo:OAE_0000199 a rdfs:Class ; rdfs:label "hair, skin or nail AE" ; rdfs:comment "an adverse event that occurs in hair, skin, or nail." ; rdfs:subClassOf obo:OAE_0000001 . obo:CIDO_0000921 a rdfs:Class ; rdfs:label "SARS-CoV2 nsp7 protein binding to human SELENOS" ; rdfs:comment "SARS-CoV2 nsp7 protein binding to human SELENOS, as evidented by an affinity-purification mass spectrometry experiment" ; rdfs:subClassOf obo:CIDO_0000049 . obo:PR_000044733 a rdfs:Class ; rdfs:label "tripartite motif-containing protein" ; rdfs:comment "A protein that contains a tripartite motif composed of three zinc-binding domains, a RING finger, one or two B-box motifs, a coiled-coil region and a highly variable C-terminal region." ; rdfs:subClassOf obo:PR_000000001 . obo:CIDO_0001129 a rdfs:Class ; rdfs:label "SARS-CoV2 orf8 protein binding to human PLEKHF2"@en ; rdfs:comment "SARS-CoV2 orf8 protein binding to human PLEKHF2, as evidented by an affinity-purification mass spectrometry experiment" ; rdfs:subClassOf obo:CIDO_0000051 . obo:OBI_0002611 a rdfs:Class ; rdfs:label "vagina swab specimen" ; rdfs:comment "A specimen that is collected with a swab from the surface of a vagina." ; rdfs:subClassOf obo:OBI_0002599 . obo:CHEBI_16643 a rdfs:Class ; rdfs:label "L-methionine" ; rdfs:comment "The L-enantiomer of methionine." ; rdfs:subClassOf obo:CHEBI_15705 , obo:CHEBI_16811 , obo:CHEBI_22658 , obo:CHEBI_83813 . a rdfs:Class ; rdfs:label "CYCLOSPORINE" ; rdfs:subClassOf . obo:NCBITaxon_305405 a rdfs:Class ; rdfs:label "SARS coronavirus A031" ; rdfs:subClassOf obo:NCBITaxon_694009 . obo:CIDO_0000115 a rdfs:Class ; rdfs:label "SARS-CoV-2 entry into endosome"@en ; rdfs:comment "A coronavirus-host interaction by which the coronavirus enters the endosome inside a host cell" ; rdfs:subClassOf obo:CIDO_0000088 . obo:CHEBI_32550 a rdfs:Class ; rdfs:label "L-lysinate" ; rdfs:comment "An optically active form of lysinate having L-configuration." ; rdfs:subClassOf obo:CHEBI_32563 , obo:CHEBI_59814 . obo:NCBITaxon_1788465 a rdfs:Class ; rdfs:label "Miniopterus bat coronavirus BtCoV/3759-1" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:CIDO_0000932 a rdfs:Class ; rdfs:label "SARS-CoV2 nsp8 protein binding to human LARP7" ; rdfs:comment "SARS-CoV2 nsp8 protein binding to human LARP7, as evidented by an affinity-purification mass spectrometry experiment" ; rdfs:subClassOf obo:CIDO_0000582 . obo:PR_000011436 a rdfs:Class ; rdfs:label "neuropilin-2" ; rdfs:comment "A protein that is a translation product of the human NRP2 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:HP_0012332 a rdfs:Class ; rdfs:label "Abnormal autonomic nervous system physiology" ; rdfs:comment "A functional abnormality of the autonomic nervous system." ; rdfs:subClassOf obo:HP_0000707 . obo:PR_000010204 a rdfs:Class ; rdfs:label "megakaryocyte-associated tyrosine-protein kinase" ; rdfs:comment "A proto-oncogene SRC-like tyrosine-protein kinase that is a translation product of the human MATK gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000002997 . a rdfs:Class ; rdfs:label "Cardiac Contractility Alteration [PE]" ; rdfs:subClassOf . obo:NCBITaxon_1897080 a rdfs:Class ; rdfs:label "Bat coronavirus Stu.lil/1613/BRA/2012" ; rdfs:subClassOf obo:NCBITaxon_366617 . obo:CHEBI_34997 a rdfs:Class ; rdfs:label "teicoplanin A2-4" ; rdfs:comment "A teicoplanin A2 that has 8-methyldecanoyl as the variable N-acyl group." ; rdfs:subClassOf obo:CHEBI_34994 . obo:NCBITaxon_434615 a rdfs:Class ; rdfs:label "Chinese ferret badger coronavirus DM95/2003" ; rdfs:subClassOf obo:NCBITaxon_11153 . obo:DRON_00019607 a rdfs:Class ; rdfs:label "tocilizumab" ; rdfs:subClassOf obo:OBI_0000047 . obo:GO_0044267 a rdfs:Class ; rdfs:label "cellular protein metabolic process" ; rdfs:comment "The chemical reactions and pathways involving a specific protein, rather than of proteins in general, occurring at the level of an individual cell. Includes cellular protein modification." ; rdfs:subClassOf obo:GO_0019538 , obo:GO_0044260 . obo:VO_0005227 a rdfs:Class ; rdfs:label "BBV154"@en ; rdfs:comment "A SARS-CoV-2 recombinant adenoviral vector vaccine that is manufactured by Bharat Biotech International Ltd. and administered intranasally" ; rdfs:subClassOf obo:VO_0005200 . obo:HP_0001394 a rdfs:Class ; rdfs:label "Cirrhosis" ; rdfs:comment "A chronic disorder of the liver in which liver tissue becomes scarred and is partially replaced by regenerative nodules and fibrotic tissue resulting in loss of liver function." ; rdfs:subClassOf obo:HP_0410042 . obo:PR_P07204 a rdfs:Class ; rdfs:label "thrombomodulin (human)" ; rdfs:comment "A thrombomodulin that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000002105 , obo:PR_000029067 . a rdfs:Class ; rdfs:label "Lymphoma, T-Cell [Disease/Finding]" ; rdfs:subClassOf . obo:PR_000008135 a rdfs:Class ; rdfs:label "golgin subfamily A member 7" ; rdfs:comment "A protein that is a translation product of the human GOLGA7 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . a rdfs:Class ; rdfs:label "Aortic Stenosis, Subvalvular [Disease/Finding]" ; rdfs:subClassOf . obo:CHEBI_36961 a rdfs:Class ; rdfs:label "chalcocarbonic acid" ; rdfs:subClassOf obo:CHEBI_36962 . obo:CHEBI_35818 a rdfs:Class ; rdfs:label "coccidiostat" ; rdfs:comment "An agent useful in the treatment or prevention of coccidiosis in man or animals." ; rdfs:subClassOf obo:CHEBI_35820 . obo:CHEBI_48354 a rdfs:Class ; rdfs:label "polar solvent" ; rdfs:comment "A solvent that is composed of polar molecules. Polar solvents can dissolve ionic compounds or ionisable covalent compounds." ; rdfs:subClassOf obo:CHEBI_46787 . obo:CIDO_0000785 a rdfs:Class ; rdfs:label "SARS-CoV2 N protein binding to human PABPC4" ; rdfs:comment "SARS-CoV2 N protein binding to human PABPC4, as evidented by an affinity-purification mass spectrometry experiment" ; rdfs:subClassOf obo:CIDO_0000056 . obo:CHEBI_35542 a rdfs:Class ; rdfs:label "5beta-cardanolide" ; rdfs:subClassOf obo:CHEBI_35543 . obo:NCBITaxon_249063 a rdfs:Class ; rdfs:label "SARS coronavirus GZ-B" ; rdfs:subClassOf obo:NCBITaxon_694009 . obo:VO_0005098 a rdfs:Class ; rdfs:label "V591"@en ; rdfs:comment "A SARS-CoV-2 vaccine candidate that uses a measles virus vector platform, and is made by Merck. Development of the vaccine was discontinued on January 25, 2021." ; rdfs:subClassOf obo:VO_0005199 . obo:CHEBI_32439 a rdfs:Class ; rdfs:label "alaninate" ; rdfs:comment "An alpha-amino-acid anion that is the conjugate base of alanine, arising from deprotonation of the carboxy group." ; rdfs:subClassOf obo:CHEBI_33558 . obo:NCBITaxon_1289547 a rdfs:Class ; rdfs:label "Coronavirus Mex_CoV-2" ; rdfs:subClassOf obo:NCBITaxon_366617 . obo:PR_000006329 a rdfs:Class ; rdfs:label "dCTP pyrophosphatase 1" ; rdfs:comment "A protein that is a translation product of the human DCTPP1 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:GO_0016043 a rdfs:Class ; rdfs:label "cellular component organization" ; rdfs:comment "A process that results in the assembly, arrangement of constituent parts, or disassembly of a cellular component." ; rdfs:subClassOf obo:GO_0009987 . obo:CIDO_0000813 a rdfs:Class ; rdfs:label "SARS-CoV2 nsp12 protein binding to human RIPK1" ; rdfs:comment "SARS-CoV2 nsp12 protein binding to human RIPK1, as evidented by an affinity-purification mass spectrometry experiment" ; rdfs:subClassOf obo:CIDO_0000057 . obo:VO_0005140 a rdfs:Class ; rdfs:label "MVvac2-MERS-solS vaccine" ; rdfs:comment "A MERS recombinant vector made of MVvac2 (measle virus) expressing a soluble, truncated version of spike glycoprotein of MERS-CoV in its full length cloned into the MVvac2 genome and rescued." ; rdfs:subClassOf obo:VO_0004900 . obo:NCBITaxon_265124 a rdfs:Class ; rdfs:label "SARS coronavirus cw037" ; rdfs:subClassOf obo:NCBITaxon_694009 . obo:NCBITaxon_1225487 a rdfs:Class ; rdfs:label "Bat coronavirus CAR/P 31/2009" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:CIDO_0000209 a rdfs:Class ; rdfs:label "SARS-CoV-2 RNA synthesis"@en ; rdfs:subClassOf obo:CIDO_0000177 , obo:CIDO_0000197 . obo:UBERON_0001968 a rdfs:Class ; rdfs:label "semen" ; rdfs:comment "Organism substance that is composed of sperm cells suspended in seminal fluid." ; rdfs:subClassOf obo:UBERON_0000463 . obo:CIDO_0000995 a rdfs:Class ; rdfs:label "SARS-CoV2 orf8 protein binding to human ERLEC1" ; rdfs:comment "SARS-CoV2 orf8 protein binding to human ERLEC1, as evidented by an affinity-purification mass spectrometry experiment" ; rdfs:subClassOf obo:CIDO_0000051 . obo:CIDO_0001148 a rdfs:Class ; rdfs:label "SARS-CoV-2 S2 protein amino acid deletion"@en ; rdfs:comment "A SARS-CoV-2 protein AA deletion that affected a SARS-CoV-2 S protein in the S2 domain." ; rdfs:subClassOf obo:CIDO_0001144 . obo:NCBITaxon_258968 a rdfs:Class ; rdfs:label "SARS coronavirus TW5" ; rdfs:subClassOf obo:NCBITaxon_694009 . obo:PR_Q05655 a rdfs:Class ; rdfs:label "protein kinase C delta type (human)" ; rdfs:comment "A protein kinase C delta type that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000002341 , obo:PR_000029067 . obo:NCBITaxon_1269305 a rdfs:Class ; rdfs:label "Coronavirus BtCoV/KCR289/Ano_geo/CRC/2010" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:PR_000001103 a rdfs:Class ; rdfs:label "5-hydroxytryptamine receptor 7" ; rdfs:comment "A 5-hydroxytryptamine receptor that is a translation product of the human HTR7 gene or a 1:1 ortholog thereof. The preferred ligand is 5-hydroxytryptamine (serotonin)." ; rdfs:subClassOf obo:PR_000044625 . obo:CIDO_0001020 a rdfs:Class ; rdfs:label "Subasumstat" ; rdfs:subClassOf obo:CHEBI_23367 . obo:CIDO_0000715 a rdfs:Class ; rdfs:label "AA variant pp1b SARS-CoV-2"@en ; rdfs:comment "An AA variant that is found within pp1b of SARS-CoV-2." ; rdfs:subClassOf obo:CIDO_0000602 . obo:PR_Q8TEM1 a rdfs:Class ; rdfs:label "nuclear pore membrane glycoprotein 210 (human)" ; rdfs:comment "A nuclear pore membrane glycoprotein 210 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000011513 , obo:PR_000029067 . obo:PR_Q9UPZ9 a rdfs:Class ; rdfs:label "serine/threonine-protein kinase ICK (human)" ; rdfs:comment "A serine/threonine-protein kinase ICK that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000008883 , obo:PR_000029067 . obo:CHEBI_25883 a rdfs:Class ; rdfs:label "pentahydroxyflavone" ; rdfs:comment "A hydroxyflavone substituted by five hydroxy groups." ; rdfs:subClassOf obo:CHEBI_24698 . obo:CIDO_0001141 a rdfs:Class ; rdfs:label "SARS-CoV-2 BA.5 virus"@en ; rdfs:comment "A SARS-CoV-2 Omicron variant virus that has a majority of the following mutations:" ; rdfs:subClassOf obo:CIDO_0000406 , obo:CIDO_0000590 . obo:HP_0002088 a rdfs:Class ; rdfs:label "Abnormal lung morphology" ; rdfs:comment "Any structural anomaly of the lung." ; rdfs:subClassOf obo:HP_0012252 . obo:CHEBI_189661 a rdfs:Class ; rdfs:label "RapaLink-1" ; rdfs:subClassOf obo:CHEBI_50860 . obo:PR_Q9UN86 a rdfs:Class ; rdfs:label "Ras GTPase-activating protein-binding protein 2 (human)" ; rdfs:comment "A Ras GTPase-activating protein-binding protein 2 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000007744 , obo:PR_000029067 . a rdfs:Class ; rdfs:label "Lipid Metabolism Alteration [PE]" ; rdfs:subClassOf . obo:PR_000008812 a rdfs:Class ; rdfs:label "heat shock cognate 71 kDa protein" ; rdfs:comment "An HSPA protein that is a translation product of the human HSPA8 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000003426 . obo:CIDO_0001118 a rdfs:Class ; rdfs:label "SARS-CoV2 orf8 protein binding to human FOXRED2"@en ; rdfs:comment "SARS-CoV2 orf8 protein binding to human FOXRED2, as evidented by an affinity-purification mass spectrometry experiment" ; rdfs:subClassOf obo:CIDO_0000051 . obo:CHEBI_48218 a rdfs:Class ; rdfs:label "antiseptic drug" ; rdfs:comment "A substance used locally on humans and other animals to destroy harmful microorganisms or to inhibit their activity (cf. disinfectants, which destroy microorganisms found on non-living objects, and antibiotics, which can be transported through the lymphatic system to destroy bacteria within the body)." ; rdfs:subClassOf obo:CHEBI_35441 . obo:CIDO_0020217 a rdfs:Class ; rdfs:label "NxTAG Respiratory Pathogen Panel + SARS-CoV-2" ; rdfs:seeAlso ; rdfs:subClassOf obo:CIDO_0000454 . obo:CHEBI_38314 a rdfs:Class ; rdfs:label "pyrazines" ; rdfs:subClassOf obo:CHEBI_38313 . obo:PR_000016881 a rdfs:Class ; rdfs:label "peroxisomal leader peptide-processing protease" ; rdfs:comment "A protein that is a translation product of the human TYSND1 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:IDO_0000498 a rdfs:Class ; rdfs:label "active immunization against infectious agent"@en ; rdfs:comment "An immunization that begins with exposure of an organism to antigen and results in immunity against an infectious agent."@en ; rdfs:subClassOf obo:IDO_0000497 . obo:PR_000014432 a rdfs:Class ; rdfs:label "scaffold attachment factor B1" ; rdfs:comment "A protein that is a translation product of the human SAFB gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:CIDO_0000230 a rdfs:Class ; rdfs:label "SARS-CoV-2 clade S virus"@en ; rdfs:comment "A SARS-CoV-2 variant virus that has a signature variant ORF8-L84S." ; rdfs:subClassOf obo:CIDO_0000405 . a rdfs:Class ; rdfs:label "Pyrrolidines [Chemical/Ingredient]" ; rdfs:subClassOf . obo:DOID_0081014 a rdfs:Class ; rdfs:label "non-severe COVID-19"@en ; rdfs:comment "A COVID-19 that is characterized by the absence of any criteria for severe or critical COVID-19." ; rdfs:subClassOf obo:DOID_0080600 . a rdfs:Class ; rdfs:label "Rhabditida Infections [Disease/Finding]" ; rdfs:subClassOf . a rdfs:Class ; rdfs:label "Peripheral Nervous System Activity Alteration [PE]" ; rdfs:subClassOf . obo:NCBITaxon_379583 a rdfs:Class ; rdfs:label "Feliformia" ; rdfs:subClassOf obo:NCBITaxon_33554 . obo:PR_Q6PML9 a rdfs:Class ; rdfs:label "zinc transporter 9 (human)" ; rdfs:comment "A zinc transporter 9 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000015082 , obo:PR_000029067 . obo:CHEBI_83403 a rdfs:Class ; rdfs:label "monochlorobenzenes" ; rdfs:comment "Any member of the class of chlorobenzenes containing a mono- or poly-substituted benzene ring in which only one substituent is chlorine." ; rdfs:subClassOf obo:CHEBI_23132 . obo:PR_000011470 a rdfs:Class ; rdfs:label "BDNF/NT-3 growth factors receptor" ; rdfs:comment "A TRK receptor that is a translation product of the human NTRK2 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000021997 . obo:PR_P07948 a rdfs:Class ; rdfs:label "tyrosine-protein kinase Lyn (human)" ; rdfs:comment "A tyrosine-protein kinase Lyn that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000010002 , obo:PR_000029067 . obo:CHEBI_23443 a rdfs:Class ; rdfs:label "cyclic amide" ; rdfs:subClassOf obo:CHEBI_32988 . obo:CHEBI_35845 a rdfs:Class ; rdfs:label "gout suppressant" ; rdfs:comment "A drug that increases uric acid excretion by the kidney (uricosuric drug), decreases uric acid production (antihyperuricemic), or alleviates the pain and inflammation of acute attacks of gout." ; rdfs:subClassOf obo:CHEBI_35842 . obo:NCBITaxon_1288700 a rdfs:Class ; rdfs:label "Bat coronavirus POA/2012/E9" ; rdfs:subClassOf obo:NCBITaxon_366617 . obo:CHEBI_63580 a rdfs:Class ; rdfs:label "Ribavirin" ; rdfs:comment "A 1-ribosyltriazole that is the 1-ribofuranosyl derivative of 1,2,4-triazole-3-carboxamide. A synthetic guanosine analogue, it is an inhibitor of HCV polymerase and possesses a broad spectrum of activity against DNA and RNA viruses." ; rdfs:subClassOf obo:CHEBI_140324 , obo:CHEBI_29347 , obo:CHEBI_37622 , obo:CHEBI_62733 , obo:CHEBI_63594 . obo:IDO_0000590 a rdfs:Class ; rdfs:label "chronic infectious disease course"@en ; rdfs:comment "An infectious disease course that unfolds over a long period of time."@en ; rdfs:subClassOf obo:IDO_0000495 . obo:CIDO_0000136 a rdfs:Class ; rdfs:label "SARS-CoV binding to host cell"@en ; rdfs:subClassOf obo:CIDO_0000134 . obo:PR_000011471 a rdfs:Class ; rdfs:label "NT-3 growth factor receptor" ; rdfs:comment "A TRK receptor that is a translation product of the human NTRK3 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000021997 . obo:NCBITaxon_996627 a rdfs:Class ; rdfs:label "Bat coronavirus M.ful/Japan/02/2009" ; rdfs:subClassOf obo:NCBITaxon_366617 . obo:CHEBI_26179 a rdfs:Class ; rdfs:label "polyether antibiotic" ; rdfs:subClassOf obo:CHEBI_25807 . a rdfs:Class ; rdfs:label "Bacterial Infections and Mycoses [Disease/Finding]" ; rdfs:subClassOf obo:IDO_0000436 . obo:CHEBI_38037 a rdfs:Class ; rdfs:label "methanesulfonate salt" ; rdfs:subClassOf obo:CHEBI_48544 , obo:CHEBI_64382 . obo:OBI_0100016 a rdfs:Class ; rdfs:label "blood plasma specimen"@en ; rdfs:comment "a material entity which corresponds to the liquid component of blood, in which the blood cells are suspended."@en ; rdfs:subClassOf obo:OBI_0000953 . obo:PR_000000721 a rdfs:Class ; rdfs:label "voltage-gated potassium channel Erg alpha subunit" ; rdfs:comment "A voltage-gated potassium channel alpha subunit with PAS domain that is characterized by its nanomolar sensitivity to class III antiarrhythmic drugs." ; rdfs:subClassOf obo:PR_000000682 . obo:NCBITaxon_34880 a rdfs:Class ; rdfs:label "Nyctereutes procyonoides" ; rdfs:subClassOf obo:NCBITaxon_34879 . obo:NCBITaxon_1699343 a rdfs:Class ; rdfs:label "Myotis Bat Alphacoronavirus strain YNXY_48C" ; rdfs:subClassOf obo:NCBITaxon_366617 . obo:OBI_0002971 a rdfs:Class ; rdfs:label "endotracheal tube specimen" ; rdfs:comment "A specimen that derives from a biofilm that forms on the inner surface of an endotracheal tube while the tube is in the trachea. The specimen is collected upon removal of the tube from the trachea." ; rdfs:subClassOf obo:OBI_0001479 . obo:CIDO_0000017 a rdfs:Class ; rdfs:label "COVID-19 diagnostic process by CT chest scanning"@en ; rdfs:comment "A COVID-19 diagnostic process that uses a computed tomography (CT)." ; rdfs:subClassOf obo:CIDO_0000033 . obo:NCBITaxon_1508226 a rdfs:Class ; rdfs:label "Neixiang Md bat coronavirus" ; rdfs:subClassOf obo:NCBITaxon_2727984 . obo:CIDO_0000350 a rdfs:Class ; rdfs:label "SARS-CoV-2 entry into cytosol"@en ; rdfs:comment "A coronavirus-host interaction by which the coronavirus enters the cytosol of a host cell" ; rdfs:subClassOf obo:CIDO_0000088 . obo:CHEBI_48279 a rdfs:Class ; rdfs:label "serotonergic antagonist" ; rdfs:comment "Drugs that bind to but do not activate serotonin receptors, thereby blocking the actions of serotonin or serotonergic agonists." ; rdfs:subClassOf obo:CHEBI_48278 . obo:VO_0005087 a rdfs:Class ; rdfs:label "DelNS1-2019-nCoV-RBD-OPT1"@en ; rdfs:comment "An influenza virus vector SARS-CoV-2 vaccine administered as an intranasal spray manufactured by University of Hong Kong, Xiamen University, and Beijing Wantai Biological Pharmacy." ; rdfs:subClassOf obo:VO_0005199 . obo:CHEBI_16234 a rdfs:Class ; rdfs:label "hydroxide" ; rdfs:subClassOf obo:CHEBI_33693 . obo:PR_000011410 a rdfs:Class ; rdfs:label "nuclear receptor subfamily 4 group A member 3" ; rdfs:comment "A protein that is a translation product of the human NR4A3 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:CIDO_0000595 a rdfs:Class ; rdfs:label "AA variant in SARS-CoV-2 S protein S2 region"@en ; rdfs:comment "An AA variant that is located in the S2 region of SARS-CoV-2 S protein. In the original Wuhan strain, this contains amino acids from position 696 to end of the protein." ; rdfs:subClassOf obo:CIDO_0000591 . obo:NCBITaxon_11152 a rdfs:Class ; rdfs:label "Turkey coronavirus" ; rdfs:subClassOf obo:NCBITaxon_694014 . obo:CHEBI_63684 a rdfs:Class ; rdfs:label "(+)-(11R,2'S)-erythro-mefloquine" ; rdfs:comment "An optically active form of [2,8-bis(trifluoromethyl)quinolin-4-yl]-(2-piperidyl)methanol having (+)-(11R,2'S)-erythro-configuration. An antimalarial agent, used in racemic form, which acts as a blood schizonticide; its mechanism of action is unknown." ; rdfs:subClassOf obo:CHEBI_63681 . obo:APOLLO_SV_00000075 a rdfs:Class ; rdfs:label "infectious disease control objective specification"@en ; rdfs:comment "An objective specification that is realized by processes that are able or likely to stop the spread of a disease in a population."@en ; rdfs:subClassOf obo:IAO_0000005 . obo:PR_000010846 a rdfs:Class ; rdfs:label "myosin light chain kinase 2, skeletal/cardiac muscle" ; rdfs:comment "A protein that is a translation product of the human MYLK2 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:PR_P36896 a rdfs:Class ; rdfs:label "activin receptor type-1B (human)" ; rdfs:comment "An activin receptor type-1B that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000000068 , obo:PR_000029067 . obo:CHEBI_9636 a rdfs:Class ; rdfs:label "Toremifene citrate" ; rdfs:subClassOf obo:CHEBI_26776 . obo:APOLLO_SV_00000086 a rdfs:Class ; rdfs:label "infectious disease control strategy"@en ; rdfs:comment "A plan specification whose objective specification is an infectious disease control objective specification."@en ; rdfs:subClassOf obo:IAO_0000104 . obo:CHEBI_27314 a rdfs:Class ; rdfs:label "water-soluble vitamin (role)" ; rdfs:comment "Any vitamin that dissolves in water and readily absorbed into tissues for immediate use. Unlike the fat-soluble vitamins, they are not stored in the body and need to be replenished regularly in the diet and will rarely accumulate to toxic levels since they are quickly excreted from the body via urine." ; rdfs:subClassOf obo:CHEBI_33229 . obo:PR_000031907 a rdfs:Class ; rdfs:label "complex I intermediate-associated protein 30, mitochondrial" ; rdfs:comment "A protein that is a translation product of the human NDUFAF1 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:DRON_00061920 a rdfs:Class ; rdfs:label "Chlorpromazine hydrochloride 200 MG Extended Release Capsule" ; rdfs:subClassOf obo:DRON_00021290 . obo:CHEBI_26201 a rdfs:Class ; rdfs:label "polyprenyl group" ; rdfs:subClassOf obo:CHEBI_26249 . obo:CHEBI_22660 a rdfs:Class ; rdfs:label "aspartic acid" ; rdfs:comment "An alpha-amino acid that consists of succinic acid bearing a single alpha-amino substituent" ; rdfs:subClassOf obo:CHEBI_26167 , obo:CHEBI_33704 , obo:CHEBI_66873 . obo:CHEBI_38515 a rdfs:Class ; rdfs:label "isoquinoline alkaloid fundamental parent" ; rdfs:subClassOf obo:CHEBI_35506 . obo:VO_0005261 a rdfs:Class ; rdfs:label "CoVepiT"@en ; rdfs:comment "A SARS-CoV-2 subunit vaccine by OSE Immunotherapeutics" ; rdfs:subClassOf obo:VO_0005202 . obo:NCBITaxon_1384461 a rdfs:Class ; rdfs:label "Bat coronavirus CDPHE15/USA/2006" ; rdfs:subClassOf obo:NCBITaxon_1913643 . obo:GO_0030316 a rdfs:Class ; rdfs:label "osteoclast differentiation" ; rdfs:comment "The process in which a relatively unspecialized monocyte acquires the specialized features of an osteoclast. An osteoclast is a specialized phagocytic cell associated with the absorption and removal of the mineralized matrix of bone tissue." ; rdfs:subClassOf obo:GO_0048869 . obo:DOID_0080848 a rdfs:Class ; rdfs:label "long COVID"@en ; rdfs:comment "A Coronavirus infectious disease that is characterized by long-term persistent and fluctuating symptoms, in individuals with COVID-19, persisting beyond three to four weeks, including the loss of the ability to smell and taste, breathlessness, fatigue, difficulty in breathing, difficulty concentrating, memory loss, confusion, headache, heart palpitations, chest pain, pain with deep breaths, dizziness, and tachycardia." ; rdfs:subClassOf obo:DOID_0080599 . obo:CIDO_0000271 a rdfs:Class ; rdfs:label "angiotensin II binding to angiotensin II type 1 receptor"@en ; rdfs:comment "Easheta, Oliver" ; rdfs:subClassOf obo:GO_0016485 . obo:VO_0005335 a rdfs:Class ; rdfs:label "SII B.1.617.2"@en ; rdfs:comment "A SARS-CoV-2 monovalent protein subunit vaccine by Novavax immunizing against the B.1.617.2 (Delta) variant and containing the Matrix-M1 adjuvant" ; rdfs:subClassOf obo:VO_0005202 . obo:OBI_0000909 a rdfs:Class ; rdfs:label "cloacal specimen" ; rdfs:comment """A specimen obtained by inserting a swab deeply into the vent of the cloaca of an organism and vigorously swabbing the wall. The swab should be deeply stained with fecal material and is then placed in transport medium.""" ; rdfs:subClassOf obo:OBI_0100051 . obo:DRON_00016421 a rdfs:Class ; rdfs:label "lopinavir" ; rdfs:subClassOf obo:OBI_0000047 . obo:NCBITaxon_305416 a rdfs:Class ; rdfs:label "SARS coronavirus C025" ; rdfs:subClassOf obo:NCBITaxon_694009 . obo:GO_0070201 a rdfs:Class ; rdfs:label "regulation of establishment of protein localization" ; rdfs:comment "Any process that modulates the frequency, rate or extent of the directed movement of a protein to a specific location." ; rdfs:subClassOf obo:GO_0032880 . obo:NCBITaxon_983923 a rdfs:Class ; rdfs:label "Chaerephon bat coronavirus/Kenya/KY41/2006" ; rdfs:subClassOf obo:NCBITaxon_366617 . obo:CIDO_0000155 a rdfs:Class ; rdfs:label "coronavirus transmission"@en ; rdfs:subClassOf obo:TRANS_0000000 . a rdfs:Class ; rdfs:label "Warfarin [Chemical/Ingredient]" ; rdfs:subClassOf . obo:OAE_0000166 a rdfs:Class ; rdfs:label "tremor AE" ; rdfs:comment "Tremor AE is a behavior and neurological AE that has an outcome of an involuntary trembling or quivering, and muscle contraction and relaxation." ; rdfs:subClassOf obo:OAE_0000580 . obo:CIDO_0000946 a rdfs:Class ; rdfs:label "SARS-CoV2 nsp8 protein binding to human SRP72" ; rdfs:comment "SARS-CoV2 nsp8 protein binding to human SRP72, as evidented by an affinity-purification mass spectrometry experiment" ; rdfs:subClassOf obo:CIDO_0000582 . obo:CIDO_0000670 a rdfs:Class ; rdfs:label "G339D in SARS-CoV-2 S protein" ; rdfs:comment "An AA mutation or AA variant that has mutated an amino acid at position 339 into a aspartic acid in S protein." ; rdfs:subClassOf obo:CIDO_0000593 . obo:CHEBI_32114 a rdfs:Class ; rdfs:label "salicylamide" ; rdfs:comment "The simplest member of the class of salicylamides derived from salicylic acid." ; rdfs:subClassOf obo:CHEBI_33853 , obo:CHEBI_53443 . obo:CHEBI_36047 a rdfs:Class ; rdfs:label "antibacterial drug" ; rdfs:comment "A drug used to treat or prevent bacterial infections." ; rdfs:subClassOf obo:CHEBI_33282 , obo:CHEBI_36043 . obo:VO_0005321 a rdfs:Class ; rdfs:label "COVID-19 subunit vaccine by HIPRA"@en ; rdfs:comment "A SARS-CoV-2 protein subunit vaccine by Laboratorios HIPRA" ; rdfs:subClassOf obo:VO_0005202 . obo:CHEBI_78000 a rdfs:Class ; rdfs:label "perindopril(1-)" ; rdfs:comment "A monocarboxylic acid anion that is the conjugate base of perindopril, obtained by deprotonation of the hydroxy group; major species at pH 7.3." ; rdfs:subClassOf obo:CHEBI_35757 . obo:NCBITaxon_2687257 a rdfs:Class ; rdfs:label "Ozimops sp. alphacoronavirus" ; rdfs:subClassOf obo:NCBITaxon_366617 . a rdfs:Class ; rdfs:label "NELFINAVIR MESYLATE" ; rdfs:subClassOf . obo:NCBITaxon_231519 a rdfs:Class ; rdfs:label "SARS coronavirus HKU-36871" ; rdfs:subClassOf obo:NCBITaxon_694009 . a rdfs:Class ; rdfs:label "Pharyngitis [Disease/Finding]" ; rdfs:subClassOf , . obo:UBERON_0002167 a rdfs:Class ; rdfs:label "right lung" ; rdfs:comment "Lung which consists of the right upper lobe, middle lobe and right lower lobe.[FMA]" ; rdfs:subClassOf obo:UBERON_0002048 . a rdfs:Class ; rdfs:label "Skin Diseases, Genetic [Disease/Finding]" ; rdfs:subClassOf , . obo:PR_000016550 a rdfs:Class ; rdfs:label "torsin-1A" ; rdfs:comment "A protein that is a translation product of the human TOR1A gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:PR_000009197 a rdfs:Class ; rdfs:label "tyrosine-protein kinase JAK2" ; rdfs:comment "A Janus kinase that is a translation product of the human JAK2 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000025748 . obo:UBERON_0000061 a rdfs:Class ; rdfs:label "anatomical structure" ; rdfs:comment "Material anatomical entity that is a single connected structure with inherent 3D shape generated by coordinated expression of the organism's own genome." ; rdfs:subClassOf obo:UBERON_0000465 , obo:UBERON_0001062 . obo:CIDO_0000897 a rdfs:Class ; rdfs:label "SARS-CoV2 nsp7 protein binding to human DNAJC19" ; rdfs:comment "SARS-CoV2 nsp7 protein binding to human DNAJC19, as evidented by an affinity-purification mass spectrometry experiment" ; rdfs:subClassOf obo:CIDO_0000049 . obo:NCBITaxon_2687256 a rdfs:Class ; rdfs:label "Falsistrellus mackenziei alphacoronavirus" ; rdfs:subClassOf obo:NCBITaxon_366617 . obo:CHEBI_33675 a rdfs:Class ; rdfs:label "p-block molecular entity" ; rdfs:comment "A p-block molecular entity is a molecular entity containing one or more atoms of a p-block element." ; rdfs:subClassOf obo:CHEBI_33579 . obo:CHEBI_35856 a rdfs:Class ; rdfs:label "lipoxygenase inhibitor" ; rdfs:comment "A compound or agent that combines with lipoxygenase and thereby prevents its substrate-enzyme combination with arachidonic acid and the formation of the icosanoid products hydroxyicosatetraenoic acid and various leukotrienes." ; rdfs:subClassOf obo:CHEBI_76837 . obo:GO_0051283 a rdfs:Class ; rdfs:label "negative regulation of sequestering of calcium ion" ; rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of the binding or confining calcium ions such that they are separated from other components of a biological system." ; rdfs:subClassOf obo:GO_0048523 , obo:GO_0051282 . obo:PR_000013639 a rdfs:Class ; rdfs:label "Ras-related protein Rab-7a" ; rdfs:comment "A protein that is a translation product of the human RAB7A gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:VO_0000341 a rdfs:Class ; rdfs:label "intranasal route" ; rdfs:comment "rounte of administration that located in nose." ; rdfs:subClassOf obo:VO_0000574 . obo:PR_000001158 a rdfs:Class ; rdfs:label "Toll-like receptor 7" ; rdfs:comment "A Toll-like receptor that is a translation product of the human TLR7 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000001096 . obo:OAE_0000588 a rdfs:Class ; rdfs:label "hematopoietic system AE" ; rdfs:comment "an adverse event which occurs in a hematopoietic system, which is any structural or developmental anomaly of the blood cells or the organs associated with the development and formation of blood cells"@en ; rdfs:subClassOf obo:OAE_0000001 . obo:CIDO_0000850 a rdfs:Class ; rdfs:label "SARS-CoV2 nsp13 protein binding to human NINL" ; rdfs:comment "SARS-CoV2 nsp13 protein binding to human NINL, as evidented by an affinity-purification mass spectrometry experiment" ; rdfs:subClassOf obo:CIDO_0000058 . a rdfs:Class ; rdfs:label "Lymphoma, Non-Hodgkin [Disease/Finding]" ; rdfs:subClassOf . obo:VO_0005245 a rdfs:Class ; rdfs:label "DS-5670a"@en ; rdfs:comment "A SARS-CoV-2 mRNA vaccine manufactured by Daiichi Sankyo Co., Ltd." ; rdfs:subClassOf obo:VO_0005198 . obo:PR_P0C264 a rdfs:Class ; rdfs:label "uncharacterized serine/threonine-protein kinase SBK3 (human)" ; rdfs:comment "An uncharacterized serine/threonine-protein kinase SBK3 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000029067 , obo:PR_000029138 . obo:PR_P41143 a rdfs:Class ; rdfs:label "delta-type opioid receptor (human)" ; rdfs:comment "A delta-type opioid receptor that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000001579 , obo:PR_000029067 . obo:NCBITaxon_9655 a rdfs:Class ; rdfs:label "Mustelidae" ; rdfs:subClassOf obo:NCBITaxon_379584 . obo:CIDO_0000342 a rdfs:Class ; rdfs:label "GINASVVNIQKEIDR"@en ; rdfs:subClassOf obo:CIDO_0000314 . obo:VO_0000496 a rdfs:Class ; rdfs:label "disorder prevention" ; rdfs:comment "disorder prevention is a processual entity that prevents a disorder that is the physical basis of a disease." ; rdfs:subClassOf obo:BFO_0000015 . obo:PR_000001576 a rdfs:Class ; rdfs:label "adenosine receptor A2a" ; rdfs:comment "An adenosine receptor protein that is a translation product of the human ADORA2A gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000001439 . obo:CHEBI_25483 a rdfs:Class ; rdfs:label "naphthoic acid" ; rdfs:comment "An aromatic carboxylic acid that consists of a naphthalene skeleton substituted by one or more carboxy groups." ; rdfs:subClassOf obo:CHEBI_25477 , obo:CHEBI_33859 . obo:NCBITaxon_1699327 a rdfs:Class ; rdfs:label "Myotis Bat Alphacoronavirus strain YNXY_17C" ; rdfs:subClassOf obo:NCBITaxon_366617 . obo:CHEBI_39281 a rdfs:Class ; rdfs:label "fluoromethanes" ; rdfs:comment "A halomethane that is methane in which one or more hydrogens has been replaced by fluorine." ; rdfs:subClassOf obo:CHEBI_24067 , obo:CHEBI_39279 . obo:NCBITaxon_424365 a rdfs:Class ; rdfs:label "Bat coronavirus HKU5-3" ; rdfs:subClassOf obo:NCBITaxon_694008 . a rdfs:Class ; rdfs:label "Cellular or Molecular Interactions [MoA]" ; rdfs:subClassOf obo:BFO_0000015 . obo:OMRSE_00000011 a rdfs:Class ; rdfs:label "patient role"@en ; rdfs:comment "A role borne by an organism and that is realized by presenting to a health care provider in a clinical encounter."@en ; rdfs:subClassOf obo:OMRSE_00000010 . obo:VO_0005205 a rdfs:Class ; rdfs:label "COVID-19 virus-like particle vaccine"@en ; rdfs:subClassOf obo:VO_0004908 . a rdfs:Class ; rdfs:label "Cellular Structure Alteration [PE]" ; rdfs:subClassOf . obo:HP_0006688 a rdfs:Class ; rdfs:label "Paroxysmal tachycardia" ; rdfs:subClassOf obo:HP_0001649 . obo:NCBITaxon_1288695 a rdfs:Class ; rdfs:label "Bat coronavirus POA/2012/B01" ; rdfs:subClassOf obo:NCBITaxon_366617 . obo:GO_0044249 a rdfs:Class ; rdfs:label "cellular biosynthetic process" ; rdfs:comment "The chemical reactions and pathways resulting in the formation of substances, carried out by individual cells." ; rdfs:subClassOf obo:GO_0009058 , obo:GO_0044237 . obo:NCBITaxon_2086356 a rdfs:Class ; rdfs:label "Neotropic cormorant coronavirus" ; rdfs:subClassOf obo:NCBITaxon_694014 . obo:DRON_00016769 a rdfs:Class ; rdfs:label "Mycophenolic Acid" ; rdfs:subClassOf obo:OBI_0000047 . obo:NCBITaxon_9972 a rdfs:Class ; rdfs:label "Manidae" ; rdfs:subClassOf obo:NCBITaxon_9971 . obo:CIDO_0000498 a rdfs:Class ; rdfs:label "FDVVFGHGAGSVVFV" ; rdfs:comment "A coronavirus epitope that is part of some S protein from HCoV NL63 composed of the following amino acids FDVVFGHGAGSVVFV" ; rdfs:subClassOf obo:CIDO_0000449 . obo:CHEBI_32851 a rdfs:Class ; rdfs:label "L-valinate" ; rdfs:comment "The L-enantiomer of valinate." ; rdfs:subClassOf obo:CHEBI_32859 , obo:CHEBI_59814 . obo:IAO_0000064 a rdfs:Class ; rdfs:label "algorithm"@en ; rdfs:comment "A plan specification which describes inputs, output of mathematical functions as well as workflow of execution for achieving an predefined objective. Algorithms are realized usually by means of implementation as computer programs for execution by automata."@en ; rdfs:subClassOf obo:IAO_0000104 . obo:OBI_0002509 a rdfs:Class ; rdfs:label "sweat specimen" ; rdfs:comment "A specimen that is derived from sweat." ; rdfs:subClassOf obo:OBI_2000009 . obo:CHEBI_23357 a rdfs:Class ; rdfs:label "cofactor" ; rdfs:comment "An organic molecule or ion (usually a metal ion) that is required by an enzyme for its activity. It may be attached either loosely (coenzyme) or tightly (prosthetic group)." ; rdfs:subClassOf obo:CHEBI_52206 . obo:PR_000029090 a rdfs:Class ; rdfs:label "atypical kinase COQ8B, mitochondrial" ; rdfs:comment "A protein that is a translation product of the human COQ8B gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:CIDO_0020165 a rdfs:Class ; rdfs:label "HealthQuest Esoterics TaqPath SARS-CoV-2 Assay" ; rdfs:seeAlso ; rdfs:subClassOf obo:CIDO_0000454 . obo:CHEBI_24675 a rdfs:Class ; rdfs:label "hydroxybenzoate" ; rdfs:comment "Any benzoate derivative carrying a single carboxylate group and at least one hydroxy substituent." ; rdfs:subClassOf obo:CHEBI_22718 , obo:CHEBI_36059 . obo:GO_0030534 a rdfs:Class ; rdfs:label "adult behavior" ; rdfs:comment "Behavior in a fully developed and mature organism." ; rdfs:subClassOf obo:GO_0007610 . obo:CHEBI_61778 a rdfs:Class ; rdfs:label "triterpenoid saponin" ; rdfs:comment "A terpene glycoside in which the terpene moiety is a triterpenoid." ; rdfs:subClassOf obo:CHEBI_26605 , obo:CHEBI_61777 . obo:GO_0019637 a rdfs:Class ; rdfs:label "organophosphate metabolic process" ; rdfs:comment "The chemical reactions and pathways involving organophosphates, any phosphate-containing organic compound." ; rdfs:subClassOf obo:GO_0006793 , obo:GO_0071704 . obo:CHEBI_46889 a rdfs:Class ; rdfs:label "S-[2,3-bis(palmitoyloxy)propyl]-Cys-Ser-Lys-Lys-Lys-Lys" ; rdfs:comment "A triacyl lipopeptide that is the pentapeptide Cys-Ser-Lys-Lys-Lys-Lys in which the side-chain thiol hydrogen on the Cys residue has been replaced by a 2,3-bis(palmitoyloxy)propyl group." ; rdfs:subClassOf obo:CHEBI_16385 , obo:CHEBI_46896 . obo:CHEBI_15356 a rdfs:Class ; rdfs:label "cysteine" ; rdfs:comment "A sulfur-containing amino acid that is propanoic acid with an amino group at position 2 and a sulfanyl group at position 3." ; rdfs:subClassOf obo:CHEBI_26167 , obo:CHEBI_26834 , obo:CHEBI_33704 . obo:PR_000031475 a rdfs:Class ; rdfs:label "probable dolichyl pyrophosphate Glc1Man9GlcNAc2 alpha-1,3-glucosyltransferase" ; rdfs:comment "A protein that is a translation product of the human ALG8 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:CIDO_0020125 a rdfs:Class ; rdfs:label "Elecsys Anti-Sars-CoV-2" ; rdfs:seeAlso ; rdfs:subClassOf obo:CIDO_0000454 . obo:CIDO_0000465 a rdfs:Class ; rdfs:label "AQALNSLLQQLFNKF" ; rdfs:comment "A coronavirus epitope that is part of some S protein from HCoV HKU1 composed of the following amino acids AQALNSLLQQLFNKF" ; rdfs:subClassOf obo:CIDO_0000409 . obo:CHEBI_16375 a rdfs:Class ; rdfs:label "D-cysteine" ; rdfs:comment "An optically active form of cysteine having D-configuration." ; rdfs:subClassOf obo:CHEBI_15356 , obo:CHEBI_16733 . obo:PR_000015755 a rdfs:Class ; rdfs:label "serine/threonine-protein kinase 38-like" ; rdfs:comment "A protein that is a translation product of the human STK38L gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:PR_P51149 a rdfs:Class ; rdfs:label "Ras-related protein Rab-7a (human)" ; rdfs:comment "A Ras-related protein Rab-7a that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000013639 , obo:PR_000029067 . obo:CHEBI_28976 a rdfs:Class ; rdfs:label "carbonic acid" ; rdfs:subClassOf obo:CHEBI_35605 , obo:CHEBI_36961 . obo:HP_0040064 a rdfs:Class ; rdfs:label "Abnormality of limbs" ; rdfs:subClassOf obo:HP_0000118 . obo:CIDO_0000903 a rdfs:Class ; rdfs:label "SARS-CoV2 nsp7 protein binding to human MOGS" ; rdfs:comment "SARS-CoV2 nsp7 protein binding to human MOGS, as evidented by an affinity-purification mass spectrometry experiment" ; rdfs:subClassOf obo:CIDO_0000049 . obo:PR_Q9Y6E0 a rdfs:Class ; rdfs:label "serine/threonine-protein kinase 24 (human)" ; rdfs:comment "A serine/threonine-protein kinase 24 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000002349 , obo:PR_000029067 . obo:NCBITaxon_233261 a rdfs:Class ; rdfs:label "Bovine coronavirus (strain LSU-94LSS-051)" ; rdfs:subClassOf obo:NCBITaxon_231419 . obo:CIDO_0000418 a rdfs:Class ; rdfs:label "immune signature role"@en ; rdfs:comment "Note: This term is now obsolete. Check 'COVID-19 immune signature role' or 'biomarker role'" ; rdfs:subClassOf obo:CIDO_0000409 . obo:UBERON_0000310 a rdfs:Class ; rdfs:label "breast" ; rdfs:comment "The upper ventral region of the torso of an organism." ; rdfs:subClassOf obo:UBERON_0000465 . obo:CHEBI_25807 a rdfs:Class ; rdfs:label "organooxygen heterocyclic antibiotic" ; rdfs:subClassOf obo:CHEBI_24531 . obo:CIDO_0020013 a rdfs:Class ; rdfs:label "Aeon Global Health SARS-CoV-2 Assay" ; rdfs:seeAlso ; rdfs:subClassOf obo:CIDO_0000454 . obo:CHEBI_61355 a rdfs:Class ; rdfs:label "3-hydroxy carboxylic acid" ; rdfs:comment "Any hydroxy carboxylic acid which contains a hydroxy group located beta- to the carboxylic acid group." ; rdfs:subClassOf obo:CHEBI_24669 . obo:DOID_3324 a rdfs:Class ; rdfs:label "mood disorder" ; rdfs:comment "A cognitive disorder that involves a disturbance in mood as the predominant underlying feature." ; rdfs:subClassOf obo:DOID_1561 . obo:GO_0006936 a rdfs:Class ; rdfs:label "muscle contraction" ; rdfs:comment "A process in which force is generated within muscle tissue, resulting in a change in muscle geometry. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis." ; rdfs:subClassOf obo:GO_0003008 . obo:NCBITaxon_266148 a rdfs:Class ; rdfs:label "SARS coronavirus Sin_WNV" ; rdfs:subClassOf obo:NCBITaxon_694009 . obo:CHEBI_26421 a rdfs:Class ; rdfs:label "pyridines" ; rdfs:comment "Any organonitrogen heterocyclic compound based on a pyridine skeleton and its substituted derivatives." ; rdfs:subClassOf obo:CHEBI_25693 , obo:CHEBI_38101 . obo:CIDO_0000865 a rdfs:Class ; rdfs:label "SARS-CoV2 nsp14 protein binding to human SIRT5" ; rdfs:comment "SARS-CoV2 nsp14 protein binding to human SIRT5, as evidented by an affinity-purification mass spectrometry experiment" ; rdfs:subClassOf obo:CIDO_0000059 . obo:PR_000015189 a rdfs:Class ; rdfs:label "sodium-dependent serotonin transporter" ; rdfs:comment "A protein that is a translation product of the human SLC6A4 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:CHEBI_50630 a rdfs:Class ; rdfs:label "cyclooxygenase 1 inhibitor" ; rdfs:comment "A cyclooxygenase inhibitor that interferes with the action of cyclooxygenase 1." ; rdfs:subClassOf obo:CHEBI_35544 . obo:CHEBI_50339 a rdfs:Class ; rdfs:label "4-aminobutyl group" ; rdfs:subClassOf obo:CHEBI_50325 . obo:GO_0032386 a rdfs:Class ; rdfs:label "regulation of intracellular transport" ; rdfs:comment "Any process that modulates the frequency, rate or extent of the directed movement of substances within cells." ; rdfs:subClassOf obo:GO_0051049 , obo:GO_0060341 . obo:GO_0009581 a rdfs:Class ; rdfs:label "detection of external stimulus" ; rdfs:comment "The series of events in which an external stimulus is received by a cell and converted into a molecular signal." ; rdfs:subClassOf obo:GO_0009605 , obo:GO_0051606 . obo:CHEBI_32840 a rdfs:Class ; rdfs:label "D-serinate" ; rdfs:comment "The D-enantiomer of serinate." ; rdfs:subClassOf obo:CHEBI_32845 . obo:PR_000010152 a rdfs:Class ; rdfs:label "mitogen-activated protein kinase 11" ; rdfs:comment "A map kinase p38 that is a translation product of the human MAPK11 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000003106 . obo:GO_0019222 a rdfs:Class ; rdfs:label "regulation of metabolic process" ; rdfs:comment "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways within a cell or an organism." ; rdfs:subClassOf obo:GO_0050789 . obo:CIDO_0000782 a rdfs:Class ; rdfs:label "SARS-CoV2 N protein binding to human LARP1" ; rdfs:comment "SARS-CoV2 N protein binding to human LARP1, as evidented by an affinity-purification mass spectrometry experiment" ; rdfs:subClassOf obo:CIDO_0000056 . obo:PR_000002111 a rdfs:Class ; rdfs:label "tyrosine-protein kinase ITK/TSK" ; rdfs:comment "A TEC-type tyrosine-protein kinase that is a translation product of the human ITK gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000001967 . obo:GO_0023052 a rdfs:Class ; rdfs:label "signaling" ; rdfs:comment "The entirety of a process in which information is transmitted within a biological system. This process begins with an active signal and ends when a cellular response has been triggered." ; rdfs:subClassOf obo:GO_0008150 . obo:CHEBI_23924 a rdfs:Class ; rdfs:label "enzyme inhibitor" ; rdfs:comment "A compound or agent that combines with an enzyme in such a manner as to prevent the normal substrate-enzyme combination and the catalytic reaction." ; rdfs:subClassOf obo:CHEBI_35222 , obo:CHEBI_52206 . obo:CHEBI_35295 a rdfs:Class ; rdfs:label "homopolycyclic compound" ; rdfs:subClassOf obo:CHEBI_33597 , obo:CHEBI_33635 . obo:GO_0048013 a rdfs:Class ; rdfs:label "ephrin receptor signaling pathway" ; rdfs:comment "The series of molecular signals initiated by ephrin binding to its receptor, and ending with the regulation of a downstream cellular process, e.g. transcription." ; rdfs:subClassOf obo:GO_0007169 . obo:NCBITaxon_497934 a rdfs:Class ; rdfs:label "Bat coronavirus M.das/Germany/D3.6/2007" ; rdfs:subClassOf obo:NCBITaxon_366617 . obo:VO_0000630 a rdfs:Class ; rdfs:label "licensed vaccine role" ; rdfs:comment "licensed vaccine role is a regulation-assigned role that indicates that a vaccine obtains official approval for commercial production and selling on the market." ; rdfs:subClassOf obo:VO_0000615 . obo:GO_1901214 a rdfs:Class ; rdfs:label "regulation of neuron death" ; rdfs:comment "Any process that modulates the frequency, rate or extent of neuron death." ; rdfs:subClassOf obo:GO_0010941 . obo:CHEBI_47779 a rdfs:Class ; rdfs:label "aminoglycoside" ; rdfs:subClassOf obo:CHEBI_24400 , obo:CHEBI_63299 . a rdfs:Class ; rdfs:label "Reserpine [Chemical/Ingredient]" ; rdfs:subClassOf . obo:NCBITaxon_749438 a rdfs:Class ; rdfs:label "Snow goose coronavirus WIR-159" ; rdfs:subClassOf obo:NCBITaxon_749416 . obo:NCBITaxon_242743 a rdfs:Class ; rdfs:label "SARS coronavirus FRA" ; rdfs:subClassOf obo:NCBITaxon_694009 . obo:CHEBI_35573 a rdfs:Class ; rdfs:label "organic mancude parent" ; rdfs:subClassOf obo:CHEBI_33245 , obo:CHEBI_35568 . obo:CHEBI_23003 a rdfs:Class ; rdfs:label "carbamate ester" ; rdfs:comment "Any ester of carbamic acid or its N-substituted derivatives." ; rdfs:subClassOf obo:CHEBI_33308 . obo:CIDO_0000331 a rdfs:Class ; rdfs:label "NFSQILPDPSKPSKR"@en ; rdfs:subClassOf obo:CIDO_0000314 . a rdfs:Class ; rdfs:label "Colitis, Ulcerative [Disease/Finding]" ; rdfs:subClassOf , . obo:CHEBI_52217 a rdfs:Class ; rdfs:label "pharmaceutical" ; rdfs:comment "Any substance introduced into a living organism with therapeutic or diagnostic purpose." ; rdfs:subClassOf obo:CHEBI_33232 . obo:CHEBI_32762 a rdfs:Class ; rdfs:label "L-tyrosinium" ; rdfs:comment "An optically active form of tyrosinium having L-configuration." ; rdfs:subClassOf obo:CHEBI_32786 . obo:PR_000014025 a rdfs:Class ; rdfs:label "receptor-interacting serine/threonine-protein kinase 4" ; rdfs:comment "A protein that is a translation product of the human RIPK4 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:NCBITaxon_389240 a rdfs:Class ; rdfs:label "Bat coronavirus (BtCoV/364A/2005)" ; rdfs:subClassOf obo:NCBITaxon_389126 . a rdfs:Class ; rdfs:label "Pyrazoles [Chemical/Ingredient]" ; rdfs:subClassOf . obo:GO_1903725 a rdfs:Class ; rdfs:label "regulation of phospholipid metabolic process" ; rdfs:comment "Any process that modulates the frequency, rate or extent of phospholipid metabolic process." ; rdfs:subClassOf obo:GO_0019216 , obo:GO_0019220 . obo:CHEBI_36685 a rdfs:Class ; rdfs:label "chlorocarboxylic acid" ; rdfs:comment "A carboxylic acid containing at least one chloro group." ; rdfs:subClassOf obo:CHEBI_33575 , obo:CHEBI_36683 . obo:CIDO_0000910 a rdfs:Class ; rdfs:label "SARS-CoV2 nsp7 protein binding to human RAB14" ; rdfs:comment "SARS-CoV2 nsp7 protein binding to human RAB14, as evidented by an affinity-purification mass spectrometry experiment" ; rdfs:subClassOf obo:CIDO_0000049 . obo:CHEBI_36807 a rdfs:Class ; rdfs:label "hydrochloride" ; rdfs:comment "A salt formally resulting from the reaction of hydrochloric acid with an organic base." ; rdfs:subClassOf obo:CHEBI_36094 . obo:GO_0023051 a rdfs:Class ; rdfs:label "regulation of signaling" ; rdfs:comment "Any process that modulates the frequency, rate or extent of a signaling process." ; rdfs:subClassOf obo:GO_0050789 . obo:OPMI_0000524 a rdfs:Class ; rdfs:label "provenance of visit record"@en ; rdfs:comment "A provenance of record that determines the provenance of the visit record, or where the record comes from." ; rdfs:subClassOf obo:OPMI_0000512 . a rdfs:Class ; rdfs:label "Norepinephrine Transporter Interactions [MoA]" ; rdfs:subClassOf . obo:CIDO_0000623 a rdfs:Class ; rdfs:label "D3G in SARS-CoV-2 M protein" ; rdfs:comment "An AA mutation or AA variant that has mutated an amino acid at position 3 into a aspartic acid in M protein." ; rdfs:subClassOf obo:CIDO_0000619 . obo:PR_000015744 a rdfs:Class ; rdfs:label "serine/threonine-protein kinase 17B" ; rdfs:comment "A protein that is a translation product of the human STK17B gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . a rdfs:Class ; rdfs:label "Decreased Immunologically Active Molecule Degradation [PE]" ; rdfs:subClassOf , . obo:PR_000017077 a rdfs:Class ; rdfs:label "serine/threonine-protein kinase ULK1" ; rdfs:comment "A protein that is a translation product of the human ULK1 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:PR_000015765 a rdfs:Class ; rdfs:label "stomatin-like protein 2" ; rdfs:comment "A protein that is a translation product of the human STOML2 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:CIDO_0000742 a rdfs:Class ; rdfs:label "W152C in SARS-CoV-2 S protein"@en ; rdfs:comment "An AA variant that has mutated an amino acid at position 152 into cystiene in S protein." ; rdfs:subClassOf obo:CIDO_0000594 . obo:CHEBI_23905 a rdfs:Class ; rdfs:label "monoatomic anion" ; rdfs:subClassOf obo:CHEBI_22563 , obo:CHEBI_24867 . obo:CIDO_0020320 a rdfs:Class ; rdfs:label "Vibrant COVID-19 Ab Assay" ; rdfs:seeAlso ; rdfs:subClassOf obo:CIDO_0000454 . obo:CHEBI_35281 a rdfs:Class ; rdfs:label "onium betaine" ; rdfs:comment "Neutral molecules having charge-separated forms with an onium atom which bears no hydrogen atoms and that is not adjacent to the anionic atom." ; rdfs:subClassOf obo:CHEBI_27369 . a rdfs:Class ; rdfs:label "Benzamides [Chemical/Ingredient]" ; rdfs:subClassOf , . a rdfs:Class ; rdfs:label "Acids, Carbocyclic [Chemical/Ingredient]" ; rdfs:subClassOf . obo:CHEBI_76507 a rdfs:Class ; rdfs:label "marine metabolite" ; rdfs:comment "Any metabolite produced during a metabolic reaction in marine macro- and microorganisms." ; rdfs:subClassOf obo:CHEBI_25212 . a rdfs:Class ; rdfs:label "Clomipramine [Chemical/Ingredient]" ; rdfs:subClassOf . obo:VO_0005081 a rdfs:Class ; rdfs:label "Corbevax"@en ; rdfs:comment "A SARS-CoV-2 vaccine that includes a protein antigen, SARS-CoV-2 Spike RBD, adsorbed to the adjuvant Alhydrogel (Alum), in combination with another approved adjuvant, CpG 1018" ; rdfs:subClassOf obo:VO_0005269 . a rdfs:Class ; rdfs:label "Decreased Vascular Permeability [PE]" ; rdfs:subClassOf . obo:NCBITaxon_1269327 a rdfs:Class ; rdfs:label "Betacoronavirus BtCoV/KW2E-F93/Nyc_spec/GHA/2010" ; rdfs:subClassOf obo:NCBITaxon_696098 . obo:NCBITaxon_2664423 a rdfs:Class ; rdfs:label "Bat MERS-like coronavirus" ; rdfs:subClassOf obo:NCBITaxon_1335626 . obo:PR_000010536 a rdfs:Class ; rdfs:label "U3 small nucleolar ribonucleoprotein protein MPP10" ; rdfs:comment "A protein that is a translation product of the human MPHOSPH10 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:PR_P55769 a rdfs:Class ; rdfs:label "NHP2-like protein 1 (human)" ; rdfs:comment "An NHP2-like protein 1 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000011203 , obo:PR_000029067 . a rdfs:Class ; rdfs:label "Chlorophenols [Chemical/Ingredient]" ; rdfs:subClassOf , . obo:PR_000001108 a rdfs:Class ; rdfs:label "D(2)-like dopamine receptor" ; rdfs:comment "A dopamine receptor that is a product of the DRD2, DRD3, or DRD4 gene. The active form binds dopamine and its activity is mediated by G proteins that cause inhibition of adenylate cyclase." ; rdfs:subClassOf obo:PR_000044633 . obo:CIDO_0001219 a rdfs:Class ; rdfs:label "SARS-CoV-2 Nucleic Acid Detection Kit (RNA capture probe method) (Shanghai Rendu BIOTECHNOLOGY Co., Ltd.)" ; rdfs:comment "Scope of application/Intended use: This kit is used for in vitro qualitative detection of novel coronavirus (2019-nCoV) in oropharyngeal swabs and sputum samples of suspected cases of novel coronavirus pneumonia, clustered cases, and other people who need to be diagnosed or differentially diagnosed with novel coronavirus infection. ORF1ab gene." ; rdfs:subClassOf obo:CIDO_0000021 . a rdfs:Class ; rdfs:label "Intestinal Neoplasms [Disease/Finding]" ; rdfs:subClassOf , . obo:NCBITaxon_1788476 a rdfs:Class ; rdfs:label "Miniopterus bat coronavirus BtCoV/4036-2" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:PR_000044625 a rdfs:Class ; rdfs:label "5-hydroxytryptamine receptor" ; rdfs:comment "A rhodopsin-like G-protein coupled receptor that is a translation product of the human HTR1A, HTR1B, HTR1D, HTR1E, HTR1F, HTR2A, HTR2B, HTR2C, HTR4, HTR5A, HTR5B, HTR6, or HTR7 genes, 1:1 orthologs thereof, or a semi-ortholog thereof." ; rdfs:subClassOf obo:PR_000001094 . obo:CHEBI_33286 a rdfs:Class ; rdfs:label "agrochemical" ; rdfs:comment "An agrochemical is a substance that is used in agriculture or horticulture." ; rdfs:subClassOf obo:CHEBI_33232 . a rdfs:Class ; rdfs:label "Infectious Diseases [Disease/Finding]" ; rdfs:subClassOf obo:IDO_0000436 . obo:CIDO_0000450 a rdfs:Class ; rdfs:label "HCoV HKU1 S protein epitope"@en ; rdfs:subClassOf obo:CIDO_0000409 . a rdfs:Class ; rdfs:label "Benztropine [Chemical/Ingredient]" ; rdfs:subClassOf . a rdfs:Class ; rdfs:label "Connective Tissue Diseases [Disease/Finding]" ; rdfs:subClassOf . obo:VO_0005151 a rdfs:Class ; rdfs:label "SARS-CoV Baculovirus S protein Vaccine" ; rdfs:comment "A SARS-CoV recombinant vector made from a baculovirus vector expressing SARS-CoV S protein." ; rdfs:subClassOf obo:VO_0012183 . obo:PR_000016176 a rdfs:Class ; rdfs:label "transcription factor 12" ; rdfs:comment "A protein that is a translation product of the human TCF12 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:DOID_6950 a rdfs:Class ; rdfs:label "combat disorder" ; rdfs:comment "An acute stress disorder that involves neurotic reactions to unusual, severe, or overwhelming military stress." ; rdfs:subClassOf obo:DOID_6088 . obo:NCBITaxon_903575 a rdfs:Class ; rdfs:label "Kenya bat coronavirus BtKY107" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:CIDO_0000065 a rdfs:Class ; rdfs:label "COVID-19 test specificity"@en ; rdfs:comment "A test specificity for the COVID-19 disease" ; rdfs:subClassOf obo:OBCS_0000095 . obo:NCBITaxon_871678 a rdfs:Class ; rdfs:label "Feline coronavirus UU17" ; rdfs:subClassOf obo:NCBITaxon_12663 . a rdfs:Class ; rdfs:label "Hemic and Lymphatic Diseases [Disease/Finding]" ; rdfs:subClassOf . obo:DOID_1203 a rdfs:Class ; rdfs:label "drug-induced mental disorder" ; rdfs:subClassOf obo:DOID_8646 . obo:CHEBI_25106 a rdfs:Class ; rdfs:label "macrolide" ; rdfs:comment "A macrocyclic lactone with a ring of twelve or more members derived from a polyketide." ; rdfs:subClassOf obo:CHEBI_26188 , obo:CHEBI_63944 . obo:OBI_0002525 a rdfs:Class ; rdfs:label "tibial artery specimen" ; rdfs:comment "A specimen that is derived from tibial artery." ; rdfs:subClassOf obo:OBI_0001479 . a rdfs:Class ; rdfs:label "Neoplasms by Site [Disease/Finding]" ; rdfs:subClassOf . obo:CIDO_0001042 a rdfs:Class ; rdfs:label "SARS-CoV2 orf9b protein binding to human SLC9A3R1" ; rdfs:comment "SARS-CoV2 orf9b protein binding to human SLC9A3R1, as evidented by an affinity-purification mass spectrometry experiment" ; rdfs:subClassOf obo:CIDO_0000052 . obo:OGG_3000001435 a rdfs:Class ; rdfs:label "CSF1" ; rdfs:comment "Other designations: lanimostim|macrophage colony-stimulating factor 1" ; rdfs:subClassOf obo:OGG_2060009606 . obo:CHEBI_58955 a rdfs:Class ; rdfs:label "branched-chain fatty acid anion" ; rdfs:comment "Any fatty acid anion with a carbon side-chain or isopropyl termination." ; rdfs:subClassOf obo:CHEBI_28868 . obo:PR_Q9H2P9 a rdfs:Class ; rdfs:label "diphthine methyl ester synthase (human)" ; rdfs:comment "A diphthine methyl ester synthase that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000006655 , obo:PR_000029067 . obo:CIDO_0000106 a rdfs:Class ; rdfs:label "interruption to MERS-CoV cell invasion"@en ; rdfs:comment "A process that interrupts SARS-CoV viral entry to host cell" ; rdfs:subClassOf obo:CIDO_0000102 . obo:CHEBI_35584 a rdfs:Class ; rdfs:label "purine" ; rdfs:comment "A heterobicyclic aromatic organic compound comprising a pyrimidine ring fused to an imidazole ring; the parent compound of the purines." ; rdfs:subClassOf obo:CHEBI_26401 , obo:CHEBI_35570 . obo:CIDO_0020222 a rdfs:Class ; rdfs:label "OPTI SARS-CoV-2 RT PCR Test" ; rdfs:seeAlso ; rdfs:subClassOf obo:CIDO_0000454 . obo:CIDO_0001107 a rdfs:Class ; rdfs:label "SARS-CoV2 orf9b protein binding to human BAG5"@en ; rdfs:comment "SARS-CoV2 orf9b protein binding to human BAG5, as evidented by an affinity-purification mass spectrometry experiment" ; rdfs:subClassOf obo:CIDO_0000052 . obo:NCBITaxon_240552 a rdfs:Class ; rdfs:label "SARS coronavirus TWS" ; rdfs:subClassOf obo:NCBITaxon_694009 . obo:NCBITaxon_2042561 a rdfs:Class ; rdfs:label "Coronavirus PREDICT CoV-36" ; rdfs:subClassOf obo:NCBITaxon_366617 . obo:CHEBI_76857 a rdfs:Class ; rdfs:label "EC 1.3.1.* (oxidoreductase acting on donor CH-CH group, NAD(+) or NADP(+) as acceptor) inhibitor" ; rdfs:comment "An EC 1.3.* (oxidoreductase acting on donor CH-CH group) inhibitor that interferes with the action of any such enzyme using NAD(+) or NADP(+) as acceptor (EC 1.3.1.*)." ; rdfs:subClassOf obo:CHEBI_76729 . obo:PR_000029188 a rdfs:Class ; rdfs:label "cAMP-dependent protein kinase catalytic subunit" ; rdfs:comment "A protein that has a core domain composition consisting of a Protein kinase domain (Pfam:PF00069). Prototype members of this class are the catalytic subunit of PKA. Protein Kinase A (PKA) catalyzes the transfer of the terminal phosphate of ATP to Thr or Ser residues in a variety of protein substrates. The enzyme is composed of two subunit types: a catalytic subunit and a regulatory subunit. In the absence of cAMP, the two subunits are bound to each other and no catalysis can take place. In the presence of cAMP, the regulatory subunit binds cAMP, thus releasing the catalytic subunit." ; rdfs:subClassOf obo:PR_000000001 . obo:PR_Q14012 a rdfs:Class ; rdfs:label "calcium/calmodulin-dependent protein kinase type 1 (human)" ; rdfs:comment "A calcium/calmodulin-dependent protein kinase type 1 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000004988 , obo:PR_000029067 . obo:DOID_4964 a rdfs:Class ; rdfs:label "neurotic disorder" ; rdfs:comment "An anxiety disorder that involves discress but neither delusions nor hallucinations." ; rdfs:subClassOf obo:DOID_2030 . obo:NCBITaxon_497940 a rdfs:Class ; rdfs:label "Bat coronavirus P.nat/Germany/D5.16/2007" ; rdfs:subClassOf obo:NCBITaxon_366617 . obo:CHEBI_88341 a rdfs:Class ; rdfs:label "pyrrolotriazine" ; rdfs:comment "Any organic heterobicyclic compound containing ortho-fused pyrrolidine and triazine rings." ; rdfs:subClassOf obo:CHEBI_27171 , obo:CHEBI_38101 . obo:NCBITaxon_1532175 a rdfs:Class ; rdfs:label "Alphacoronavirus BtCoV/VH_NC2/Neo_cap/RSA/2012" ; rdfs:subClassOf obo:NCBITaxon_366617 . obo:PR_Q7LGA3 a rdfs:Class ; rdfs:label "heparan sulfate 2-O-sulfotransferase 1 (human)" ; rdfs:comment "A heparan sulfate 2-O-sulfotransferase 1 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000008757 , obo:PR_000029067 . obo:NCBITaxon_745727 a rdfs:Class ; rdfs:label "Coronavirus N.noc/VM199/2007/NLD" ; rdfs:subClassOf obo:NCBITaxon_696098 . obo:CIDO_0000655 a rdfs:Class ; rdfs:label "R52I in SARS-CoV-2 NS8 protein" ; rdfs:comment "An AA mutation or AA variant that has mutated an amino acid at position 52 into a isoleucine in ns8." ; rdfs:subClassOf obo:CIDO_0000617 . obo:CHEBI_24835 a rdfs:Class ; rdfs:label "inorganic molecular entity" ; rdfs:comment "A molecular entity that contains no carbon." ; rdfs:subClassOf obo:CHEBI_23367 . obo:NCBITaxon_233264 a rdfs:Class ; rdfs:label "Bovine respiratory coronavirus (strain 98TXSF-110-LUN)" ; rdfs:subClassOf obo:NCBITaxon_11128 . obo:CIDO_0000361 a rdfs:Class ; rdfs:label "hydrolysis of angiotensinogen to angiotensin I"@en ; rdfs:subClassOf obo:GO_0016485 . obo:CIDO_0000771 a rdfs:Class ; rdfs:label "SARS-CoV2 M protein binding to human STOM" ; rdfs:comment "SARS-CoV2 M protein binding to human STOM, as evidented by an affinity-purification mass spectrometry experiment" ; rdfs:subClassOf obo:CIDO_0000055 . obo:CIDO_0000726 a rdfs:Class ; rdfs:label "T15671I in SARS-CoV-2 pp1a protein"@en ; rdfs:comment "An AA mutation or AA variant that has mutated an amino acid at position 1567 into isoleucine in pp1a." ; rdfs:subClassOf obo:CIDO_0001074 . obo:PR_Q9H845 a rdfs:Class ; rdfs:label "complex I assembly factor ACAD9, mitochondrial (human)" ; rdfs:comment "A complex I assembly factor ACAD9, mitochondrial that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000003599 , obo:PR_000029067 . obo:CHEBI_28965 a rdfs:Class ; rdfs:label "dicarboxylic acid dianion" ; rdfs:comment "A carboxylic acid dianion obtained by deprotonation of both carboxy groups of any dicarboxylic acid." ; rdfs:subClassOf obo:CHEBI_35693 , obo:CHEBI_38716 . obo:CHEBI_50910 a rdfs:Class ; rdfs:label "neurotoxin" ; rdfs:comment "A poison that interferes with the functions of the nervous system." ; rdfs:subClassOf obo:CHEBI_52209 , obo:CHEBI_64909 . obo:PR_Q99567 a rdfs:Class ; rdfs:label "nuclear pore complex protein Nup88 (human)" ; rdfs:comment "A nuclear pore complex protein Nup88 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000011524 , obo:PR_000029067 . obo:CIDO_0001159 a rdfs:Class ; rdfs:label "AA variant in SARS-CoV-2 S protein S2 FP region"@en ; rdfs:subClassOf obo:CIDO_0000595 . obo:PR_000005869 a rdfs:Class ; rdfs:label "corticotropin-releasing factor receptor 1" ; rdfs:comment "A corticotropin-releasing factor receptor that is a translation product of the human CRHR1 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000044630 . obo:CIDO_0000195 a rdfs:Class ; rdfs:label "host-SARS-CoV-2 interaction"@en ; rdfs:subClassOf obo:CIDO_0000084 . obo:HP_0005305 a rdfs:Class ; rdfs:label "Cerebral venous thrombosis" ; rdfs:comment "Formation of a blood clot (thrombus) inside a cerebral vein, causing the obstruction of blood flow." ; rdfs:subClassOf obo:HP_0001977 . obo:CIDO_0001031 a rdfs:Class ; rdfs:label "MAS825" ; rdfs:subClassOf obo:CHEBI_23367 . obo:PR_000016372 a rdfs:Class ; rdfs:label "transducin-like enhancer protein 1" ; rdfs:comment "A protein that is a translation product of the human TLE1 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:OGG_100011118 a rdfs:Class ; rdfs:label "genome of coronavirus" ; rdfs:comment "A genome that is the genome of a coronavirus." ; rdfs:subClassOf obo:OGG_100010239 . obo:CIDO_0020126 a rdfs:Class ; rdfs:label "Elecsys Anti-SARS-CoV-2 S" ; rdfs:seeAlso ; rdfs:subClassOf obo:CIDO_0000454 . a rdfs:Class ; rdfs:label "Abnormalities, Drug-Induced [Disease/Finding]" ; rdfs:subClassOf . obo:DOID_0070085 a rdfs:Class ; rdfs:label "schizophrenia 9" ; rdfs:comment "A schizophrenia that has_material_basis_in a mutation of DISC1 on chromosome 1q42.2." ; rdfs:subClassOf obo:DOID_0050177 , obo:DOID_5419 . obo:PR_000008456 a rdfs:Class ; rdfs:label "hemoglobin subunit alpha" ; rdfs:comment "A hemoglobin subunit that is a translation product of the human HBA1 or HBA2 genes, 1:1 orthologs thereof, or a semi-ortholog thereof." ; rdfs:subClassOf obo:PR_000050467 . obo:CIDO_0000757 a rdfs:Class ; rdfs:label "SARS-CoV2 M protein binding to human FASTKD5" ; rdfs:comment "SARS-CoV2 M protein binding to human FASTKD5, as evidented by an affinity-purification mass spectrometry experiment" ; rdfs:subClassOf obo:CIDO_0000055 . obo:GO_0033238 a rdfs:Class ; rdfs:label "regulation of cellular amine metabolic process" ; rdfs:comment "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways by which individual cells transform amines." ; rdfs:subClassOf obo:GO_0031323 , obo:GO_0051171 . obo:PR_000000017 a rdfs:Class ; rdfs:label "interferon gamma" ; rdfs:comment "A type II interferon that is a translation product of the human IFNG gene or a 1:1 ortholog thereof. The core domain structure consists of an Interferon gamma domain (Pfam:PF00714) that is four-helical cytokine domain with an additional helix in one of the crossover connections. It is a cytokine produced by lymphocytes activated by specific antigens or mitogens that has important immunoregulatory functions." ; rdfs:subClassOf obo:PR_000024990 . obo:PR_000016491 a rdfs:Class ; rdfs:label "TRAF2 and NCK-interacting protein kinase" ; rdfs:comment "A protein that is a translation product of the human TNIK gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:CIDO_0000796 a rdfs:Class ; rdfs:label "SARS-CoV2 nsp1 protein binding to human PRIM2" ; rdfs:comment "SARS-CoV2 nsp1 protein binding to human PRIM2, as evidented by an affinity-purification mass spectrometry experiment" ; rdfs:subClassOf obo:CIDO_0000062 . obo:PR_000004995 a rdfs:Class ; rdfs:label "calcium/calmodulin-dependent protein kinase kinase 2" ; rdfs:comment "A protein that is a translation product of the human CAMKK2 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:OBI_2000014 a rdfs:Class ; rdfs:label "venous blood specimen" ; rdfs:comment "A specimen that is derived from some venous blood" ; rdfs:subClassOf obo:OBI_2000009 . obo:CHEBI_37407 a rdfs:Class ; rdfs:label "cyclic ether" ; rdfs:comment "Any ether in which the oxygen atom forms part of a ring." ; rdfs:subClassOf obo:CHEBI_25698 , obo:CHEBI_38104 . a rdfs:Class ; rdfs:label "Digitoxin [Chemical/Ingredient]" ; rdfs:subClassOf . obo:CIDO_0001152 a rdfs:Class ; rdfs:label "SARS-CoV-2 M protein amino acid deletion"@en ; rdfs:comment "A SARS-CoV-2 protein AA deletion that affected a SARS-CoV-2 M protein." ; rdfs:subClassOf obo:CIDO_0000614 . obo:CIDO_0020098 a rdfs:Class ; rdfs:label "COVID-19 RT-PCR Test Pathology/Laboratory Medicine Lab of Baptist Hospital Miami" ; rdfs:seeAlso ; rdfs:subClassOf obo:CIDO_0000454 . obo:NCBITaxon_352849 a rdfs:Class ; rdfs:label "Parrot coronavirus AV71/99" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:PR_000050281 a rdfs:Class ; rdfs:label "rep gene proteolytic cleavage product (SARS-CoV-2)" ; rdfs:comment "A rep gene translation product (SARS-CoV-2) that has been processed by proteolytic cleavage." ; rdfs:subClassOf obo:PR_000018264 , obo:PR_000050263 . obo:NCBITaxon_1532167 a rdfs:Class ; rdfs:label "Alphacoronavirus BtCoV/GrNC4/Neo_cap/RSA/2012" ; rdfs:subClassOf obo:NCBITaxon_366617 . a rdfs:Class ; rdfs:label "Uterine Secretory Phase Alteration [PE]" ; rdfs:subClassOf . obo:CIDO_0000526 a rdfs:Class ; rdfs:label "YFSQLLCEPIKLVNS" ; rdfs:comment "A coronavirus epitope that is part of some S protein from HCoV NL63 composed of the following amino acids YFSQLLCEPIKLVNS" ; rdfs:subClassOf obo:CIDO_0000449 . obo:CHEBI_33259 a rdfs:Class ; rdfs:label "elemental molecular entity" ; rdfs:comment "A molecular entity all atoms of which have the same atomic number." ; rdfs:subClassOf obo:CHEBI_23367 . obo:OBI_2000001 a rdfs:Class ; rdfs:label "urethra specimen" ; rdfs:comment "A specimen that is derived from some urethra " ; rdfs:subClassOf obo:OBI_0001479 . obo:CIDO_0000278 a rdfs:Class ; rdfs:label "G204R in SARS-CoV-2 N protein"@en ; rdfs:subClassOf obo:CIDO_0000597 . obo:UBERON_0005178 a rdfs:Class ; rdfs:label "thoracic cavity element" ; rdfs:comment "An organ or element that is in the thoracic cavity. Examples: lung, heart, longus colli." ; rdfs:subClassOf obo:UBERON_0005177 , obo:UBERON_0005181 . obo:CHEBI_78298 a rdfs:Class ; rdfs:label "environmental contaminant" ; rdfs:comment "Any minor or unwanted substance introduced into the environment that can have undesired effects." ; rdfs:subClassOf obo:CHEBI_51086 . obo:NCBITaxon_1346293 a rdfs:Class ; rdfs:label "Betacoronavirus BtCoV/KCR180/Pte_par/CRC/2012" ; rdfs:subClassOf obo:NCBITaxon_696098 . obo:PR_000017048 a rdfs:Class ; rdfs:label "UDP-glucuronosyltransferase 1A1" ; rdfs:comment "A protein that is a translation product of the human UGT1A1 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . a rdfs:Class ; rdfs:label "E [Preparations]" ; rdfs:subClassOf . a rdfs:Class ; rdfs:label "Acquired Immunodeficiency Syndrome [Disease/Finding]" ; rdfs:subClassOf , . obo:GO_0090304 a rdfs:Class ; rdfs:label "nucleic acid metabolic process" ; rdfs:comment "Any cellular metabolic process involving nucleic acids." ; rdfs:subClassOf obo:GO_0006139 , obo:GO_0043170 . a rdfs:Class ; rdfs:label "Sexually Transmitted Diseases [Disease/Finding]" ; rdfs:subClassOf , , , obo:DOID_934 . obo:CIDO_0000282 a rdfs:Class ; rdfs:label "coronavirus life cycle"@en ; rdfs:subClassOf obo:GO_0019058 . obo:CIDO_0020341 a rdfs:Class ; rdfs:label "ZEUS ELISA SARS-CoV-2 IgG Test System" ; rdfs:seeAlso ; rdfs:subClassOf obo:CIDO_0000454 . obo:DOID_8646 a rdfs:Class ; rdfs:label "substance-induced psychosis" ; rdfs:subClassOf obo:DOID_2468 . obo:PR_P00734 a rdfs:Class ; rdfs:label "prothrombin (human)" ; rdfs:comment "A prothrombin that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000007299 , obo:PR_000029067 . obo:PR_Q13283 a rdfs:Class ; rdfs:label "Ras GTPase-activating protein-binding protein 1 (human)" ; rdfs:comment "A Ras GTPase-activating protein-binding protein 1 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000007743 , obo:PR_000029067 . obo:CHEBI_59683 a rdfs:Class ; rdfs:label "antipruritic drug" ; rdfs:comment "A drug, usually applied topically, that relieves pruritus (itching)." ; rdfs:subClassOf obo:CHEBI_50177 . obo:OAE_0000373 a rdfs:Class ; rdfs:label "pruritus AE" ; rdfs:comment "a skin adverse event that has an outcome of pruritus" ; rdfs:subClassOf obo:OAE_0000543 . obo:CHEBI_35638 a rdfs:Class ; rdfs:label "18-oxayohimban" ; rdfs:subClassOf obo:CHEBI_38482 , obo:CHEBI_38958 . obo:CHEBI_67072 a rdfs:Class ; rdfs:label "cannabinoid receptor agonist" ; rdfs:comment "An agonist that binds to and activates cannabinoid receptors." ; rdfs:subClassOf obo:CHEBI_48705 . obo:CHEBI_171664 a rdfs:Class ; rdfs:label "antiamoebic agent" ; rdfs:comment "An antiparasitic agent which is effective against amoeba, a genus of single-celled amoeboids in the family Amoebidae." ; rdfs:subClassOf obo:CHEBI_35442 . obo:CIDO_0000630 a rdfs:Class ; rdfs:label "R203M in SARS-CoV-2 N protein" ; rdfs:comment "An AA mutation or AA variant that has mutated an amino acid at position 203 into a methionine in N protein." ; rdfs:subClassOf obo:CIDO_0000596 . obo:OAE_0000388 a rdfs:Class ; rdfs:label "dizziness AE" ; rdfs:comment "a sensory capability AE that has an outcome of dizziness" ; rdfs:subClassOf obo:OAE_0000582 . obo:NCBITaxon_1699357 a rdfs:Class ; rdfs:label "Rousettus Bat Betacoronavirus strain ML_83I" ; rdfs:subClassOf obo:NCBITaxon_696098 . obo:DRON_00023182 a rdfs:Class ; rdfs:label "Promethazine Injectable Solution" ; rdfs:subClassOf obo:DRON_00000020 . obo:VO_0000812 a rdfs:Class ; rdfs:label "USA licensed vaccine role" ; rdfs:comment "a licensed vaccine role that indicates the vaccine occurs in USA." ; rdfs:subClassOf obo:VO_0000630 . a rdfs:Class ; rdfs:label "ciclesonide [Chemical/Ingredient]" ; rdfs:subClassOf . obo:PR_000011128 a rdfs:Class ; rdfs:label "serine/threonine-protein kinase Nek2" ; rdfs:comment "A protein that is a translation product of the human NEK2 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:CIDO_0000245 a rdfs:Class ; rdfs:label "rs12242C"@en ; rdfs:subClassOf obo:CIDO_0000247 . obo:UBERON_0000002 a rdfs:Class ; rdfs:label "uterine cervix" ; rdfs:comment "Lower, narrow portion of the uterus where it joins with the top end of the vagina." ; rdfs:subClassOf obo:UBERON_0000465 . obo:CHEBI_35415 a rdfs:Class ; rdfs:label "alpha-amino-acid residue cation" ; rdfs:comment "Any alpha-amino-acid residue that is positively charged." ; rdfs:subClassOf obo:CHEBI_64769 . obo:PR_P61586 a rdfs:Class ; rdfs:label "transforming protein RhoA (human)" ; rdfs:comment "A GTP-binding protein RhoA that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000000176 , obo:PR_000029067 . obo:VO_0000497 a rdfs:Class ; rdfs:label "disorder treatment" ; rdfs:comment "disorder treatment is a processual entity that leads to treat a disorder that is the physical basis of a disease." ; rdfs:subClassOf obo:BFO_0000015 . obo:CHEBI_35718 a rdfs:Class ; rdfs:label "antifungal agent" ; rdfs:comment "An antimicrobial agent that destroys fungi by suppressing their ability to grow or reproduce." ; rdfs:subClassOf obo:CHEBI_33281 . obo:VO_0005346 a rdfs:Class ; rdfs:label "COVID-19 DNA vaccine by the University of Hong Kong and Immuno Cure 3 Limited"@en ; rdfs:comment "A SARS-CoV-2 DNA vaccine developed by University of Hong Kong and Immuno Cure 3 Limited" ; rdfs:subClassOf obo:VO_0005203 . obo:NCBITaxon_511430 a rdfs:Class ; rdfs:label "SARS coronavirus BJ182-4" ; rdfs:subClassOf obo:NCBITaxon_694009 . obo:PR_000025748 a rdfs:Class ; rdfs:label "Janus kinase" ; rdfs:comment "A protein with core domain composition consisting of an N-termianl FERM domain, followed by a copy of the SH2 domain (Pfam:PF00017), and two copies of the Protein tyrosine kinase (Pfam:PF07714) domain. Janus kinase is a non-receptor tyrosine kinase." ; rdfs:subClassOf obo:PR_000000001 . obo:NCBITaxon_1643898 a rdfs:Class ; rdfs:label "Bat coronavirus ANK047F" ; rdfs:subClassOf obo:NCBITaxon_696098 . obo:CIDO_0020233 a rdfs:Class ; rdfs:label "PhoenixDx 2019-CoV" ; rdfs:seeAlso ; rdfs:subClassOf obo:CIDO_0000454 . obo:CHEBI_132922 a rdfs:Class ; rdfs:label "ibuprofen(1-)" ; rdfs:comment "A monocarboxylic acid anion that is the conjugate base of ibuprofen, obtained by deprotonation of the carboxy group; major species at pH 7.3." ; rdfs:subClassOf obo:CHEBI_35757 . obo:CIDO_0000166 a rdfs:Class ; rdfs:label "infectious droplet nuclei"@en ; rdfs:comment "Respiratory repiratory aerosols that is the residue of dried respiratory aerosols (≤ 5 um in diameter) that results from evaporation of droplets coughed or sneezed into the atmosphere or by aerosolization of infective material." ; rdfs:subClassOf obo:CIDO_0000164 . obo:NCBITaxon_903636 a rdfs:Class ; rdfs:label "Kenya bat coronavirus BtKY98" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:PR_000003939 a rdfs:Class ; rdfs:label "GDP-Man:Man(3)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase" ; rdfs:comment "A protein that is a translation product of the human ALG11 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:CHEBI_26764 a rdfs:Class ; rdfs:label "steroid hormone" ; rdfs:comment "Any steroid that acts as hormone." ; rdfs:subClassOf obo:CHEBI_35341 . obo:NCBITaxon_1746087 a rdfs:Class ; rdfs:label "Bat coronavirus P.nat/GER/1048/2013" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:NCBITaxon_1699344 a rdfs:Class ; rdfs:label "Myotis Bat Alphacoronavirus strain YNXY_50C" ; rdfs:subClassOf obo:NCBITaxon_366617 . obo:PR_000004515 a rdfs:Class ; rdfs:label "aurora kinase A" ; rdfs:comment "An aurora kinase that is a translation product of the human AURKA gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000035365 . a rdfs:Class ; rdfs:label "Blood Platelet Disorders [Disease/Finding]" ; rdfs:subClassOf . obo:NCBITaxon_1004949 a rdfs:Class ; rdfs:label "Rocky Mountain bat coronavirus 15/2006/ML" ; rdfs:subClassOf obo:NCBITaxon_366617 . obo:PR_000011096 a rdfs:Class ; rdfs:label "NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial" ; rdfs:comment "A protein that is a translation product of the human NDUFS1 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:PR_Q9NV92 a rdfs:Class ; rdfs:label "NEDD4 family-interacting protein 2 (human)" ; rdfs:comment "A NEDD4 family-interacting protein 2 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000011054 , obo:PR_000029067 . obo:PR_000001179 a rdfs:Class ; rdfs:label "D(4) dopamine receptor" ; rdfs:comment "A D(2)-like dopamine receptor that is a translation product of the human DRD4 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000001108 . obo:OBI_0600007 a rdfs:Class ; rdfs:label "administering substance in vivo"@en ; rdfs:comment "A process by which a substance is intentionally given to an organism resulting in exposure of the organism to that substance." ; rdfs:subClassOf obo:OBI_0000011 . obo:CIDO_0000645 a rdfs:Class ; rdfs:label "T3255I in SARS-CoV-2 pp1a protein" ; rdfs:comment "An AA mutation or AA variant that has mutated an amino acid at position 3255 into a isoleucine in pp1a." ; rdfs:subClassOf obo:CIDO_0001076 . obo:CHEBI_46761 a rdfs:Class ; rdfs:label "dipeptide" ; rdfs:comment "Any molecule that contains two amino-acid residues connected by peptide linkages." ; rdfs:subClassOf obo:CHEBI_25676 . obo:CHEBI_51143 a rdfs:Class ; rdfs:label "nitrogen molecular entity" ; rdfs:subClassOf obo:CHEBI_33302 . obo:PR_P09919 a rdfs:Class ; rdfs:label "granulocyte colony-stimulating factor (human)" ; rdfs:comment "A granulocyte colony-stimulating factor that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000005932 , obo:PR_000029067 . obo:RO_0000091 a rdf:Property ; rdfs:label "has disposition"@en ; rdfs:comment "a relation between an independent continuant (the bearer) and a disposition, in which the disposition specifically depends on the bearer for its existence"@en ; rdfs:range . obo:PR_O00238 a rdfs:Class ; rdfs:label "bone morphogenetic protein receptor type-1B (human)" ; rdfs:comment "A BMP receptor type-1B that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000000036 , obo:PR_000029067 . obo:CHEBI_145994 a rdfs:Class ; rdfs:label "remdesivir" ; rdfs:comment "A carboxylic ester resulting from the formal condensation of the carboxy group of N-[(S)-{[(2R,3S,4R,5R)-5-(4-aminopyrrolo[2,1-f][1,2,4]triazin-7-yl)-5-cyano-3,4-dihydroxytetrahydrofuran-2-yl]methoxy}(phenoxy)phosphoryl]-L-alanine with the hydroxy group of 2-ethylbutan-1-ol. A broad-spectrum antiviral prodrug with potent in vitro antiviral activity against a diverse panel of RNA viruses such as Ebola virus, MERS-CoV and SARS-CoV. It is currently in Phase III clinical trials for the treatment of Covid-19 in adults." ; rdfs:subClassOf obo:CHEBI_18379 , obo:CHEBI_27577 , obo:CHEBI_33308 , obo:CHEBI_33860 , obo:CHEBI_37086 , obo:CHEBI_88341 . obo:DRON_00001135 a rdfs:Class ; rdfs:label "Chloroquine injectable solution"@en ; rdfs:subClassOf obo:DRON_00001134 . obo:CHEBI_22587 a rdfs:Class ; rdfs:label "antiviral agent" ; rdfs:comment "A substance that destroys or inhibits replication of viruses." ; rdfs:subClassOf obo:CHEBI_33281 . a rdfs:Class ; rdfs:label "Tamoxifen Citrate [Chemical/Ingredient]" ; rdfs:subClassOf . obo:VO_0005395 a rdfs:Class ; rdfs:label "DoCo-Pro-RBD-1 + MF59"@en ; rdfs:comment "A SARS-CoV-2 protein subunit vaccine manufactured by the University of Melbourne." ; rdfs:subClassOf obo:VO_0005202 . obo:CIDO_0000666 a rdfs:Class ; rdfs:label "E156- in SARS-CoV-2 S protein" ; rdfs:comment "An AA mutation or AA variant that has mutated an amino acid at position 156 into a deletion" ; rdfs:subClassOf obo:CIDO_0001144 . obo:PR_000007563 a rdfs:Class ; rdfs:label "vascular endothelial growth factor receptor 1" ; rdfs:comment "A vascular endothelial growth factor receptor that is a translation product of the human FLT1 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000001971 . obo:CL_0000578 a rdfs:Class ; rdfs:label "experimentally modified cell in vitro" ; rdfs:comment "A cell in vitro that has undergone physical changes as a consequence of a deliberate and specific experimental procedure." ; rdfs:subClassOf obo:CL_0000000 , obo:OBI_0000047 . a rdfs:Class ; rdfs:label "Benzimidazoles [Chemical/Ingredient]" ; rdfs:subClassOf . a rdfs:Class ; rdfs:label "P [Preparations]" ; rdfs:subClassOf . obo:PR_000030597 a rdfs:Class ; rdfs:label "transmembrane emp24 domain-containing protein 5" ; rdfs:comment "A protein that is a translation product of the human TMED5 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:PR_000050279 a rdfs:Class ; rdfs:label "non-structural protein 10 (SARS-CoV-2)" ; rdfs:comment "A rep gene proteolytic cleavage product (SARS-CoV-2) that is the central portion produced by the enzymatic action of 3CL-PRO proteinase (nsp5) when it cleaves the precursor rep gene translation product (SARS-CoV-2) between residues 4253-4254 and 4392-4393." ; rdfs:subClassOf obo:PR_000050281 . obo:CIDO_0020185 a rdfs:Class ; rdfs:label "LIASON SARS-CoV-2 S1/S2 IgG" ; rdfs:seeAlso ; rdfs:subClassOf obo:CIDO_0000454 . obo:NCBITaxon_903590 a rdfs:Class ; rdfs:label "Kenya bat coronavirus BtKY52" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:NCBITaxon_1346303 a rdfs:Class ; rdfs:label "Betacoronavirus BtCoV/Rhi_fer/It13/ITA/2009" ; rdfs:subClassOf obo:NCBITaxon_696098 . obo:IDO_0000547 a rdfs:Class ; rdfs:label "virulence factor"@en ; rdfs:comment "A biological macromolecule produced by a pathogen and that has a virulence factor disposition."@en ; rdfs:subClassOf obo:CHEBI_23367 . obo:CHEBI_75787 a rdfs:Class ; rdfs:label "prokaryotic metabolite" ; rdfs:comment "Any metabolite produced during a metabolic reaction in prokaryotes, the taxon that include members of domains such as the bacteria and archaea." ; rdfs:subClassOf obo:CHEBI_25212 . obo:NCBITaxon_906887 a rdfs:Class ; rdfs:label "Feline coronavirus UU40" ; rdfs:subClassOf obo:NCBITaxon_12663 . obo:CHEBI_140402 a rdfs:Class ; rdfs:label "tert-butyl ester" ; rdfs:comment "A carboxylic ester resulting from the formal condensation of a carboxylic acid with tert-butanol." ; rdfs:subClassOf obo:CHEBI_33308 . obo:CIDO_0000357 a rdfs:Class ; rdfs:label "vasodilator role"@en ; rdfs:comment "A role taken by a chemical entity (including a drug or natural entity) that causes the relaxation of smooth muscle cells within the vessel walls, in particular in the large veins, large arteries, and smaller arterioles, resulting in the widening of blood vessels," ; rdfs:subClassOf obo:BFO_0000023 . a rdfs:Class ; rdfs:label "Infection [Disease/Finding]" ; rdfs:subClassOf . obo:VO_0005133 a rdfs:Class ; rdfs:label "MVvac2-MERS-S(H) vaccine" ; rdfs:comment "A MERS recombinant vector vaccine made of live-attenuated measles virus (MV) vaccine encoding the MERS-CoV spike protein (MERS-S)." ; rdfs:subClassOf obo:VO_0004900 . obo:CIDO_0001003 a rdfs:Class ; rdfs:label "TMC-310911" ; rdfs:subClassOf obo:CHEBI_23367 . obo:PR_000004623 a rdfs:Class ; rdfs:label "BAG family molecular chaperone regulator 5" ; rdfs:comment "A protein that is a translation product of the human BAG5 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . a rdfs:Class ; rdfs:label "Pregnadienes [Chemical/Ingredient]" ; rdfs:subClassOf . obo:NCBITaxon_633557 a rdfs:Class ; rdfs:label "Infectious bronchitis virus CK/CH/LHLJ/04V" ; rdfs:subClassOf obo:NCBITaxon_11120 . obo:OBI_0000376 a rdfs:Class ; rdfs:label "synthesizing function"@en ; rdfs:comment "A synthesizing function is a function to assemble new output materials from distinct input materials. The output materials typically consist of chemically distinct monomeric objects or object aggregate polymers." ; rdfs:subClassOf obo:BFO_0000034 . obo:HP_0011688 a rdfs:Class ; rdfs:label "Supraventricular tachycardia with an accessory connection mediated pathway" ; rdfs:comment "Supraventricular tachycardia in which an accessory pathway connecting the atria and ventricles, apart from the AV node, participates as a necessary part of a reentrant mechanism." ; rdfs:subClassOf obo:HP_0004755 . obo:CHEBI_66916 a rdfs:Class ; rdfs:label "alanine zwitterion" ; rdfs:comment "An amino acid zwitterion arising from transfer of a proton from the carboxy to the amino group of alanine; major species at pH 7.3." ; rdfs:subClassOf obo:CHEBI_35238 . obo:GO_0039694 a rdfs:Class ; rdfs:label "viral RNA genome replication" ; rdfs:comment "The replication of a viral RNA genome." ; rdfs:subClassOf obo:GO_0019079 . a rdfs:Class ; rdfs:label "Facial Dermatoses [Disease/Finding]" ; rdfs:subClassOf . obo:PR_000002003 a rdfs:Class ; rdfs:label "G protein-activated inward rectifier potassium channel 2" ; rdfs:comment "A G protein-activated inward rectifier potassium channel that is a translation product of the human KCNJ6 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000001814 . obo:CHEBI_50523 a rdfs:Class ; rdfs:label "butenolide" ; rdfs:comment "A gamma-lactone that consists of a 2-furanone skeleton and its substituted derivatives." ; rdfs:subClassOf obo:CHEBI_24129 , obo:CHEBI_37581 . obo:PR_000002212 a rdfs:Class ; rdfs:label "serine/threonine-protein kinase, MST4-like" ; rdfs:comment "A protein that is a translation product of a family of genes that includes STK24, STK25, or STK26. The core architecture consists of one Protein kinase domain (Pfam:PF00069)." ; rdfs:subClassOf obo:PR_000000001 . obo:CIDO_0001064 a rdfs:Class ; rdfs:label "SARS-CoV2 orf9c protein binding to human TAPT1" ; rdfs:comment "SARS-CoV2 orf9c protein binding to human TAPT1, as evidented by an affinity-purification mass spectrometry experiment" ; rdfs:subClassOf obo:CIDO_0000054 . obo:PR_000012732 a rdfs:Class ; rdfs:label "proto-oncogene serine/threonine-protein kinase Pim-1" ; rdfs:comment "A protein that is a translation product of the human PIM1 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:CL_0000232 a rdfs:Class ; rdfs:label "erythrocyte" ; rdfs:comment "A red blood cell. In mammals, mature erythrocytes are biconcave disks containing hemoglobin whose function is to transport oxygen." ; rdfs:subClassOf obo:CL_0000000 . obo:PR_Q06432 a rdfs:Class ; rdfs:label "voltage-dependent calcium channel gamma-1 subunit (human)" ; rdfs:comment "A voltage-dependent calcium channel gamma-1 subunit that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000004950 , obo:PR_000029067 . obo:CIDO_0000764 a rdfs:Class ; rdfs:label "SARS-CoV2 M protein binding to human REEP5" ; rdfs:comment "SARS-CoV2 M protein binding to human REEP5, as evidented by an affinity-purification mass spectrometry experiment" ; rdfs:subClassOf obo:CIDO_0000055 . obo:NCBITaxon_2042547 a rdfs:Class ; rdfs:label "Coronavirus PREDICT CoV-20" ; rdfs:subClassOf obo:NCBITaxon_696098 . obo:CIDO_0000472 a rdfs:Class ; rdfs:label "ESAYMPIADPTHFDI" ; rdfs:comment "A coronavirus epitope that is part of some S protein from HCoV 229E composed of the following amino acids ESAYMPIADPTHFDI" ; rdfs:subClassOf obo:CIDO_0000451 . obo:UBERON_0000160 a rdfs:Class ; rdfs:label "intestine" ; rdfs:comment "Segment of the alimentary canal extending from the stomach to the anus and, in humans and other mammals, consists of two segments, the small intestine and the large intestine." ; rdfs:subClassOf obo:UBERON_0004921 . obo:GO_0060134 a rdfs:Class ; rdfs:label "prepulse inhibition" ; rdfs:comment "The process in which a startle magnitude is reduced when the startling stimulus is preceded by a low-intensity prepulse." ; rdfs:subClassOf obo:GO_0032102 . obo:VO_0005192 a rdfs:Class ; rdfs:label "MVC-COV1901"@en ; rdfs:comment "A SARS-CoV-2 subunit vaccine that contains the Spike (S) protein with CpG 1018 and aluminum content as adjuvant." ; rdfs:subClassOf obo:VO_0005269 . a rdfs:Class ; rdfs:label "IVERMECTIN" ; rdfs:subClassOf . a rdfs:Class ; rdfs:label "Ear Diseases [Disease/Finding]" ; rdfs:subClassOf . obo:NCBITaxon_2042591 a rdfs:Class ; rdfs:label "Coronavirus PREDICT CoV-67" ; rdfs:subClassOf obo:NCBITaxon_696098 . obo:PR_Q96AY3 a rdfs:Class ; rdfs:label "peptidyl-prolyl cis-trans isomerase FKBP10 (human)" ; rdfs:comment "A peptidyl-prolyl cis-trans isomerase FKBP10 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000007532 , obo:PR_000029067 . obo:OBI_0100026 a rdfs:Class ; rdfs:label "organism"@en ; rdfs:comment "A material entity that is an individual living system, such as animal, plant, bacteria or virus, that is capable of replicating or reproducing, growth and maintenance in the right environment. An organism may be unicellular or made up, like humans, of many billions of cells divided into specialized tissues and organs."@en ; rdfs:subClassOf obo:BFO_0000030 , obo:BFO_0000040 . obo:PR_Q9BW92 a rdfs:Class ; rdfs:label "threonine--tRNA ligase, mitochondrial (human)" ; rdfs:comment "A threonine--tRNA ligase, mitochondrial that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000016059 , obo:PR_000029067 . obo:CHEBI_38623 a rdfs:Class ; rdfs:label "EC 1.4.3.4 (monoamine oxidase) inhibitor" ; rdfs:comment "An EC 1.4.3.* (oxidoreductase acting on donor CH-NH2 group, oxygen as acceptor) inhibitor that interferes with the action of monoamine oxidase (EC 1.4.3.4)." ; rdfs:subClassOf obo:CHEBI_76861 . obo:PR_Q96PY6 a rdfs:Class ; rdfs:label "serine/threonine-protein kinase Nek1 (human)" ; rdfs:comment "A serine/threonine-protein kinase Nek1 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000011125 , obo:PR_000029067 . obo:DRON_00750789 a rdfs:Class ; rdfs:label "bazedoxifene" ; rdfs:subClassOf obo:OBI_0000047 . obo:CHEBI_9712 a rdfs:Class ; rdfs:label "triflupromazine hydrochloride" ; rdfs:subClassOf obo:CHEBI_36807 . obo:PR_000024938 a rdfs:Class ; rdfs:label "interferon alpha" ; rdfs:comment "Category=family." ; rdfs:subClassOf obo:PR_000025848 . obo:VO_0005144 a rdfs:Class ; rdfs:label "Ad5-nCoV" ; rdfs:comment "A SARS-CoV-2 vaccine made of self-coding RNA encoding SARS-CoV-2 spike protein encapsulated within a lipid nanoparticle." ; rdfs:subClassOf obo:VO_0005268 . obo:PR_000013501 a rdfs:Class ; rdfs:label "tRNA pseudouridine synthase-like 1" ; rdfs:comment "A protein that is a translation product of the human PUSL1 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:OBI_0002503 a rdfs:Class ; rdfs:label "feces specimen" ; rdfs:comment "A specimen that is derived from feces." ; rdfs:subClassOf obo:OBI_0001479 . obo:GO_0006790 a rdfs:Class ; rdfs:label "sulfur compound metabolic process" ; rdfs:comment "The chemical reactions and pathways involving the nonmetallic element sulfur or compounds that contain sulfur, such as the amino acids methionine and cysteine or the tripeptide glutathione." ; rdfs:subClassOf obo:GO_0044237 . obo:HP_0006499 a rdfs:Class ; rdfs:label "Abnormality of femoral epiphysis" ; rdfs:comment "An anomaly of a growth plate of a femur." ; rdfs:subClassOf obo:HP_0002823 , obo:HP_0006500 . obo:NCBITaxon_681852 a rdfs:Class ; rdfs:label "Kenya bat coronavirus BtKY05" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:CIDO_0020244 a rdfs:Class ; rdfs:label "QDX SARS-CoV-2 Assay" ; rdfs:seeAlso ; rdfs:subClassOf obo:CIDO_0000454 . obo:CHEBI_73398 a rdfs:Class ; rdfs:label "indole skeleton" ; rdfs:comment "A mancude heterobicyclic organic group consisting of a benzene ring fused to a pyrrole ring." ; rdfs:subClassOf obo:CHEBI_73541 . obo:UBERON_0002113 a rdfs:Class ; rdfs:label "kidney" ; rdfs:comment "A paired organ of the urinary tract which has the production of urine as its primary function." ; rdfs:subClassOf obo:UBERON_0003103 , obo:UBERON_0005177 , obo:UBERON_0015212 . obo:PR_000004807 a rdfs:Class ; rdfs:label "bromodomain-containing protein 4" ; rdfs:comment "A protein that is a translation product of the human BRD4 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:OBI_0000809 a rdfs:Class ; rdfs:label "amplified DNA" ; rdfs:comment "DNA that has been produced in an enzymatic amplification process" ; rdfs:subClassOf obo:CHEBI_16991 , obo:OBI_0000047 . obo:NCBITaxon_219112 a rdfs:Class ; rdfs:label "Paradoxurinae" ; rdfs:subClassOf obo:NCBITaxon_9673 . obo:CIDO_0000677 a rdfs:Class ; rdfs:label "L452R in SARS-CoV-2 S protein" ; rdfs:comment "An AA mutation or AA variant that has mutated an amino acid at position 452 into a arginine" ; rdfs:subClassOf obo:CIDO_0000593 . obo:DOID_2848 a rdfs:Class ; rdfs:label "melancholia" ; rdfs:subClassOf obo:DOID_1596 . obo:CIDO_0020148 a rdfs:Class ; rdfs:label "GeneFinder COVID-19 Plus RealAmp Kit" ; rdfs:seeAlso ; rdfs:subClassOf obo:CIDO_0000454 . obo:OBI_0000441 a rdfs:Class ; rdfs:label "assay objective"@en ; rdfs:comment "an objective specification to determine a specified type of information about an evaluated entity (the material entity bearing evaluant role)"@en ; rdfs:subClassOf obo:IAO_0000005 . obo:GO_0045761 a rdfs:Class ; rdfs:label "regulation of adenylate cyclase activity" ; rdfs:comment "Any process that modulates the frequency, rate or extent of adenylate cyclase activity." ; rdfs:subClassOf obo:GO_0031279 , obo:GO_0051339 . obo:GO_0048525 a rdfs:Class ; rdfs:label "negative regulation of viral process" ; rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of a multi-organism process in which a virus is a participant." ; rdfs:subClassOf obo:GO_0048519 , obo:GO_0050792 . obo:PR_000007977 a rdfs:Class ; rdfs:label "GRB10-interacting GYF protein 2" ; rdfs:comment "A protein that is a translation product of the human GIGYF2 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:CHEBI_15339 a rdfs:Class ; rdfs:label "acceptor" ; rdfs:comment "A molecular entity that can accept an electron, a pair of electrons, an atom or a group from another molecular entity." ; rdfs:subClassOf obo:CHEBI_51086 . obo:CIDO_0000204 a rdfs:Class ; rdfs:label "coronaviral molecular interaction inside host cell"@en ; rdfs:comment "A host-coronavirus molecular interaction where the focus is the coronavirus process inside a host cell at the molecular level." ; rdfs:subClassOf obo:CIDO_0000198 , obo:CIDO_0000345 . obo:UBERON_0004121 a rdfs:Class ; rdfs:label "ectoderm-derived structure" ; rdfs:comment "An anatomical structure that develops (entirely or partially) from the ectoderm." ; rdfs:subClassOf obo:UBERON_0000061 . obo:UBERON_0002048 a rdfs:Class ; rdfs:label "lung" ; rdfs:comment "Respiration organ that develops as an outpocketing of the esophagus." ; rdfs:seeAlso ; rdfs:subClassOf obo:UBERON_0000062 , obo:UBERON_0000465 , obo:UBERON_0004119 , obo:UBERON_0005178 , obo:UBERON_0015212 . obo:DRON_00000007 a rdfs:Class ; rdfs:label "portion of solution"@en ; rdfs:comment "a portion of mixture of two or more portions of pure substances whereby one or more of its pure substance parts called solute(s) is (are) dispersed evenly in another pure substance part called the solvent, whereby (1) the grains of the solvent and solute(s) are of size ≤10^-9m, and (2) the solvent typically has a much greater mass and volume than the solute(s)"@en ; rdfs:subClassOf obo:DRON_00000006 . obo:CIDO_0020251 a rdfs:Class ; rdfs:label "Quest Diagnostics HA SARS-CoV-2 Assay" ; rdfs:seeAlso ; rdfs:subClassOf obo:CIDO_0000454 . obo:OBI_0000950 a rdfs:Class ; rdfs:label "paraffin specimen" ; rdfs:comment "a specimen that is output of a paraffin storage process in which specimen is embedded in paraffin" ; rdfs:subClassOf obo:OBI_0001472 . obo:CHEBI_57560 a rdfs:Class ; rdfs:label "long-chain fatty acid anion" ; rdfs:comment "A fatty acid anion with a chain length of C13 to C22." ; rdfs:subClassOf obo:CHEBI_28868 . a rdfs:Class ; rdfs:label "Polycyclic Hydrocarbons, Aromatic [Chemical/Ingredient]" ; rdfs:subClassOf , . obo:NCBITaxon_443241 a rdfs:Class ; rdfs:label "Human coronavirus HKU1 (isolate N5)" ; rdfs:subClassOf obo:NCBITaxon_290028 . obo:NCBITaxon_249068 a rdfs:Class ; rdfs:label "SARS coronavirus HSZ2-A" ; rdfs:subClassOf obo:NCBITaxon_694009 . obo:PR_000014427 a rdfs:Class ; rdfs:label "protein SAAL1" ; rdfs:comment "A protein that is a translation product of the human SAAL1 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:HP_0002196 a rdfs:Class ; rdfs:label "Myelopathy" ; rdfs:subClassOf obo:HP_0002011 . obo:CIDO_0000735 a rdfs:Class ; rdfs:label "SARS-CoV2 M protein binding to human AAR2" ; rdfs:comment "SARS-CoV2 M protein binding to human AAR2, as evidented by an affinity-purification mass spectrometry experiment" ; rdfs:subClassOf obo:CIDO_0000055 . obo:CHEBI_33433 a rdfs:Class ; rdfs:label "monoatomic halogen" ; rdfs:subClassOf obo:CHEBI_33238 . obo:CHEBI_17891 a rdfs:Class ; rdfs:label "donor" ; rdfs:comment "A molecular entity that can transfer (\"donate\") an electron, a pair of electrons, an atom or a group to another molecular entity." ; rdfs:subClassOf obo:CHEBI_51086 . obo:CIDO_0000256 a rdfs:Class ; rdfs:label "lysosomotropic agent role"@en ; rdfs:comment "A role taked by an agent that can induce lysosomotropism. Weak bases with lipophilic properties accumulate in acidic intracellular compartments like lysosomes. While the plasma and lysosomal membranes are permeable for neutral and uncharged species of weak bases, the charged protonated species of weak bases do not permeate biomembranes and accumulate within lysosomes. The concentration within lysosomes may reach levels 100 to 1000 fold higher than extracellular concentrations. This phenomenon is called lysosomotropism, \"acid trapping\" or \"proton pump\" effect." ; rdfs:subClassOf obo:CHEBI_52206 . obo:NCBITaxon_1503289 a rdfs:Class ; rdfs:label "BtMr-AlphaCoV/SAX2011" ; rdfs:subClassOf obo:NCBITaxon_2501927 . obo:CHEBI_79389 a rdfs:Class ; rdfs:label "monovalent inorganic anion" ; rdfs:comment "Any inorganic anion with a valency of one." ; rdfs:subClassOf obo:CHEBI_24834 . obo:PR_Q4KMQ2 a rdfs:Class ; rdfs:label "anoctamin-6 (human)" ; rdfs:comment "An anoctamin-6 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000004061 , obo:PR_000029067 . obo:CHEBI_35442 a rdfs:Class ; rdfs:label "antiparasitic agent" ; rdfs:comment "A substance used to treat or prevent parasitic infections." ; rdfs:subClassOf obo:CHEBI_35441 . obo:NCBITaxon_622707 a rdfs:Class ; rdfs:label "Bat coronavirus Hipposideros/GhanaBoo/344/2008" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:PR_000007310 a rdfs:Class ; rdfs:label "fatty acid-binding protein, intestinal" ; rdfs:comment "A fatty acid-binding protein that is a translation product of the human FABP2 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000025846 . obo:NCBITaxon_389229 a rdfs:Class ; rdfs:label "Bat coronavirus (BtCoV/ A1201/2005)" ; rdfs:subClassOf obo:NCBITaxon_389126 . obo:CHEBI_123143 a rdfs:Class ; rdfs:label "N2-[2-(4-methylphenyl)-5-phenyl-3-pyrazolyl]benzene-1,2-diamine" ; rdfs:subClassOf obo:CHEBI_26410 , obo:CHEBI_36820 . a rdfs:Class ; rdfs:label "Adenoviridae Infections [Disease/Finding]" ; rdfs:subClassOf . obo:PR_000008502 a rdfs:Class ; rdfs:label "E3 ubiquitin-protein ligase HECTD1" ; rdfs:comment "A protein that is a translation product of the human HECTD1 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:CHEBI_37149 a rdfs:Class ; rdfs:label "bromobenzenes" ; rdfs:comment "A member of the class of benzenes that is benzene substituted by at least one bromo group." ; rdfs:subClassOf obo:CHEBI_22712 , obo:CHEBI_37141 . obo:CHEBI_37734 a rdfs:Class ; rdfs:label "phosphoric ester" ; rdfs:subClassOf obo:CHEBI_26079 , obo:CHEBI_35701 . obo:NCBITaxon_11151 a rdfs:Class ; rdfs:label "Porcine transmissible gastroenteritis coronavirus strain Purdue" ; rdfs:subClassOf obo:NCBITaxon_11149 . obo:PR_000008316 a rdfs:Class ; rdfs:label "general transcription factor IIF subunit 2" ; rdfs:comment "A protein that is a translation product of the human GTF2F2 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:GO_0071705 a rdfs:Class ; rdfs:label "nitrogen compound transport" ; rdfs:comment "The directed movement of nitrogen-containing compounds into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." ; rdfs:subClassOf obo:GO_0006810 . obo:NCBITaxon_11146 a rdfs:Class ; rdfs:label "Porcine respiratory coronavirus" ; rdfs:subClassOf obo:NCBITaxon_11149 . obo:PR_000005262 a rdfs:Class ; rdfs:label "CDK5 regulatory subunit-associated protein 2" ; rdfs:comment "A protein that is a translation product of the human CDK5RAP2 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:CHEBI_32988 a rdfs:Class ; rdfs:label "amide" ; rdfs:comment "An amide is a derivative of an oxoacid RkE(=O)l(OH)m (l =/= 0) in which an acidic hydroxy group has been replaced by an amino or substituted amino group." ; rdfs:subClassOf obo:CHEBI_51143 . a rdfs:Class ; rdfs:label "Amiodarone [Chemical/Ingredient]" ; rdfs:subClassOf . obo:PR_P34969 a rdfs:Class ; rdfs:label "5-hydroxytryptamine receptor 7 (human)" ; rdfs:comment "A 5-hydroxytryptamine receptor 7 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000001103 , obo:PR_000029067 . obo:CHEBI_35588 a rdfs:Class ; rdfs:label "3H-purine" ; rdfs:comment "The 3H-tautomer of purine." ; rdfs:subClassOf obo:CHEBI_35584 . a rdfs:Class ; rdfs:label "Nelfinavir Mesylate [Chemical/Ingredient]" ; rdfs:subClassOf . obo:PR_000016351 a rdfs:Class ; rdfs:label "mitochondrial import inner membrane translocase subunit Tim9" ; rdfs:comment "A protein that is a translation product of the human TIMM9 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:GO_1902531 a rdfs:Class ; rdfs:label "regulation of intracellular signal transduction" ; rdfs:comment "Any process that modulates the frequency, rate or extent of intracellular signal transduction." ; rdfs:subClassOf obo:GO_0009966 . obo:CIDO_0001213 a rdfs:Class ; rdfs:label "Multiple Real-Time PCR Kit for Detection of 2019-nCoV. (Sansure Biotech Inc.)" ; rdfs:comment "Poduct storage conditions and expiration date: Store in an airtight place protected from light at -20±5℃, valid for 11 months." ; rdfs:subClassOf obo:CIDO_0000021 . obo:PR_Q9Y312 a rdfs:Class ; rdfs:label "protein AAR2 homolog (human)" ; rdfs:comment "A protein AAR2 homolog that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000029067 , obo:PR_000031226 . obo:CHEBI_85012 a rdfs:Class ; rdfs:label "thrombopoietin receptor agonist" ; rdfs:comment "An agonist that selectively binds to and activates the thrombopoietin receptor [myeloproliferative leukemia protein or CD110 (Cluster of Differentiation 110)]." ; rdfs:subClassOf obo:CHEBI_48705 . obo:CHEBI_25558 a rdfs:Class ; rdfs:label "organonitrogen heterocyclic antibiotic" ; rdfs:subClassOf obo:CHEBI_24531 , obo:CHEBI_38101 . obo:CHEBI_76964 a rdfs:Class ; rdfs:label "Penicillium metabolite" ; rdfs:comment "Any fungal metabolite produced during a metabolic reaction in Penicillium." ; rdfs:subClassOf obo:CHEBI_76946 . obo:VO_0004995 a rdfs:Class ; rdfs:label "UB-612"@en ; rdfs:comment "A SARS-CoV-2 S1-RBD-protein based vaccine developed by Vaxxinity" ; rdfs:subClassOf obo:VO_0005202 . obo:GO_0043114 a rdfs:Class ; rdfs:label "regulation of vascular permeability" ; rdfs:comment "Any process that modulates the extent to which blood vessels can be pervaded by fluid." ; rdfs:subClassOf obo:GO_0003018 , obo:GO_0065008 . obo:CIDO_0000260 a rdfs:Class ; rdfs:label "COVID-19 real time RT-PCR diagnostic assay"@en ; rdfs:comment "A COVID-19 diagnostic assay that uses a real time RT-PCR test" ; rdfs:subClassOf obo:CIDO_0000019 . obo:CIDO_0000584 a rdfs:Class ; rdfs:label "SARS-CoV-2 orf3a protein interaction with host protein"@en ; rdfs:comment "A molecular interaction that has participant of the SARS-CoV-2 orf3a protein and a host protein" ; rdfs:subClassOf obo:CIDO_0000348 . obo:NCBITaxon_34879 a rdfs:Class ; rdfs:label "Nyctereutes" ; rdfs:subClassOf obo:NCBITaxon_9608 . obo:OPMI_0000091 a rdfs:Class ; rdfs:label "day of birth"@en ; rdfs:comment "A day when an organism (e.g., a human) is born." ; rdfs:subClassOf obo:OPMI_0000478 . obo:OBI_2000004 a rdfs:Class ; rdfs:label "eye specimen" ; rdfs:comment "A specimen that is derived from some eye " ; rdfs:subClassOf obo:OBI_0001479 . obo:CHEBI_35482 a rdfs:Class ; rdfs:label "opioid analgesic" ; rdfs:comment "A narcotic or opioid substance, synthetic or semisynthetic agent producing profound analgesia, drowsiness, and changes in mood." ; rdfs:subClassOf obo:CHEBI_35480 . obo:PR_000007296 a rdfs:Class ; rdfs:label "coagulation factor XII" ; rdfs:comment "A protein that is a translation product of the human F12 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:CHEBI_52206 a rdfs:Class ; rdfs:label "biochemical role" ; rdfs:comment "A biological role played by the molecular entity or part thereof within a biochemical context." ; rdfs:subClassOf obo:CHEBI_24432 . obo:PR_P35354 a rdfs:Class ; rdfs:label "prostaglandin G/H synthase 2 (human)" ; rdfs:comment "A prostaglandin G/H synthase 2 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000013428 , obo:PR_000029067 . obo:VO_0005315 a rdfs:Class ; rdfs:label "SCB-2020S"@en ; rdfs:comment "A SARS-CoV-2 subunit vaccine by Clover Biopharmaceuticals AUS Pty Ltd that contains the S protein from the B.1.351 variant." ; rdfs:subClassOf obo:VO_0005202 . obo:CHEBI_28225 a rdfs:Class ; rdfs:label "D-leucine" ; rdfs:comment "The D-enantiomer of leucine." ; rdfs:subClassOf obo:CHEBI_16733 , obo:CHEBI_25017 . obo:CHEBI_46770 a rdfs:Class ; rdfs:label "pyrrolidinecarboxamide" ; rdfs:subClassOf obo:CHEBI_29347 , obo:CHEBI_38260 . obo:CIDO_0000104 a rdfs:Class ; rdfs:label "interruption to SARS-CoV-2 cell invasion"@en ; rdfs:comment "A process that interrupts SARS-CoV-2 viral entry to host cell" ; rdfs:subClassOf obo:CIDO_0000102 . obo:VO_0005173 a rdfs:Class ; rdfs:label "AdimrSC-2f"@en ; rdfs:comment "A SARS-CoV-2 protein subunit vaccine developed by Adimmune Corporation." ; rdfs:subClassOf obo:VO_0005202 . obo:CHEBI_65207 a rdfs:Class ; rdfs:label "vascular endothelial growth factor receptor antagonist" ; rdfs:comment "An antagonist at the vascular endothelial growth factor receptor." ; rdfs:subClassOf obo:CHEBI_48706 . a rdfs:Class ; rdfs:label "RESERPINE" ; rdfs:subClassOf . a rdfs:Class ; rdfs:label "Ventricular Outflow Obstruction [Disease/Finding]" ; rdfs:subClassOf . obo:GO_0007613 a rdfs:Class ; rdfs:label "memory" ; rdfs:comment "The activities involved in the mental information processing system that receives (registers), modifies, stores, and retrieves informational stimuli. The main stages involved in the formation and retrieval of memory are encoding (processing of received information by acquisition), storage (building a permanent record of received information as a result of consolidation) and retrieval (calling back the stored information and use it in a suitable way to execute a given task)." ; rdfs:subClassOf obo:GO_0007611 . obo:NCBITaxon_8570 a rdfs:Class ; rdfs:label "Serpentes" ; rdfs:subClassOf obo:NCBITaxon_1329911 . obo:GO_0048878 a rdfs:Class ; rdfs:label "chemical homeostasis" ; rdfs:comment "Any biological process involved in the maintenance of an internal steady state of a chemical." ; rdfs:subClassOf obo:GO_0042592 . obo:CHEBI_64911 a rdfs:Class ; rdfs:label "antimitotic" ; rdfs:comment "Any compound that inhibits cell division (mitosis)." ; rdfs:subClassOf obo:CHEBI_52210 . obo:NCBITaxon_1446361 a rdfs:Class ; rdfs:label "Eurasian oystercatcher coronavirus" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:PR_000007188 a rdfs:Class ; rdfs:label "ERO1-like protein beta" ; rdfs:comment "A protein that is a translation product of the human ERO1B gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:PR_000007664 a rdfs:Class ; rdfs:label "tyrosine-protein kinase FRK" ; rdfs:comment "A proto-oncogene SRC-like tyrosine-protein kinase that is a translation product of the human FRK gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000002997 . obo:OBI_0002781 a rdfs:Class ; rdfs:label "lower respiratory tract aspirate specimen" ; rdfs:comment "A specimen that is collected with a suctioning tube from the lower respiratory tract." ; rdfs:subClassOf obo:OBI_0002599 . obo:NCBITaxon_1511623 a rdfs:Class ; rdfs:label "Coronavirus BtCoV/M67/HUN/2013" ; rdfs:subClassOf obo:NCBITaxon_2664420 . a rdfs:Class ; rdfs:label "Adrenergic Receptor Interactions [MoA]" ; rdfs:subClassOf . obo:NCBITaxon_389142 a rdfs:Class ; rdfs:label "Bat coronavirus (BtCoV/A633/2005)" ; rdfs:subClassOf obo:NCBITaxon_389126 . obo:APOLLO_SV_00000551 a rdfs:Class ; rdfs:label "Susceptible-Exposed-Infectious-Recovered model"@en ; rdfs:comment "A compartmental disease transmission model that represents some infection in ecosystem in which there are compartments for susceptible individuals, exposed individuals, infectious individuals, and immune inviduals, such that exposed individuals are infected but cannot transmit the pathogen."@en ; rdfs:subClassOf obo:APOLLO_SV_00000303 . obo:OBI_1110116 a rdfs:Class ; rdfs:label "splenocyte specimen"@en ; rdfs:comment "A cell specimen comprised of a mixed cell population obtained by processing whole spleen into individual cells, typically performed using a sieve or blender. This population includes T cells, B cells, macrophages, and other cell types." ; rdfs:subClassOf obo:OBI_0000953 , obo:OBI_0001468 . obo:GO_1901701 a rdfs:Class ; rdfs:label "cellular response to oxygen-containing compound" ; rdfs:comment "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an oxygen-containing compound stimulus." ; rdfs:subClassOf obo:GO_0070887 , obo:GO_1901700 . obo:PR_P52948 a rdfs:Class ; rdfs:label "nuclear pore complex protein Nup98-Nup96 (human)" ; rdfs:comment "A nuclear pore complex protein Nup98-Nup96 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000011526 , obo:PR_000029067 . obo:CHEBI_41774 a rdfs:Class ; rdfs:label "Tamoxifen" ; rdfs:comment "A tertiary amino compound that has formula C26H29NO." ; rdfs:subClassOf obo:CHEBI_26776 , obo:CHEBI_50996 . obo:CIDO_0000511 a rdfs:Class ; rdfs:label "IFINNTTYPTNVAVE" ; rdfs:comment "A coronavirus epitope that is part of some S protein from HCoV OC43 composed of the following amino acids IFINNTTYPTNVAVE" ; rdfs:subClassOf obo:CIDO_0000452 . obo:CHEBI_50112 a rdfs:Class ; rdfs:label "sex hormone" ; rdfs:comment "Any hormone that is responsible for controlling sexual characteristics and reproductive function." ; rdfs:subClassOf obo:CHEBI_24621 . obo:CHEBI_65232 a rdfs:Class ; rdfs:label "EC 3.4.21.5 (thrombin) inhibitor" ; rdfs:comment "An EC 3.4.21.* (serine endopeptidase) inhibitor that interferes with the action of thrombin (EC 3.4.21.5)." ; rdfs:subClassOf obo:CHEBI_5924 . obo:NCBITaxon_1269310 a rdfs:Class ; rdfs:label "Coronavirus BtCoV/KCR90/Car_per/CRC/2010" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:PR_000050020 a rdfs:Class ; rdfs:label "CLASP protein" ; rdfs:comment "A protein that is a translation product of the human CLASP1 or CLASP2 genes, or 1:1 orthologs thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:CIDO_0020143 a rdfs:Class ; rdfs:label "FREND COVID-19 total Ab" ; rdfs:seeAlso ; rdfs:subClassOf obo:CIDO_0000454 . obo:UBERON_0002371 a rdfs:Class ; rdfs:label "bone marrow" ; rdfs:comment "the soft tissue that fills the cavities of bones" ; rdfs:subClassOf obo:UBERON_0000479 . obo:VO_0005128 a rdfs:Class ; rdfs:label "UV-Inactivated SARS + TLR agonist vaccine" ; rdfs:comment "A SARS inactivated vaccine made from SARS-CoV inactivated by ultraviolet radiation and a Toll-Like Receptor Agonist Adjuvant is added to prevent eosinophilic immunopathology" ; rdfs:subClassOf obo:VO_0012183 . obo:DRON_00000017 a rdfs:Class ; rdfs:label "drug cream"@en ; rdfs:comment "a portion of cream that is the bearer of a clinical drug role"@en ; rdfs:subClassOf obo:DRON_00000011 . obo:DOID_1579 a rdfs:Class ; rdfs:label "respiratory system disease" ; rdfs:comment "A disease of anatomical entity that located_in the respiratory system which extends from the nasal sinuses to the diaphragm." ; rdfs:subClassOf obo:DOID_7 . obo:CHEBI_46775 a rdfs:Class ; rdfs:label "N-alkylpyrrolidine" ; rdfs:subClassOf obo:CHEBI_38260 , obo:CHEBI_50996 . obo:CIDO_0001019 a rdfs:Class ; rdfs:label "Etesevimab" ; rdfs:subClassOf obo:CHEBI_23367 . obo:PR_Q9UJ71 a rdfs:Class ; rdfs:label "C-type lectin domain family 4 member K (human)" ; rdfs:comment "A C-type lectin domain family 4 member K that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000001293 , obo:PR_000029067 . obo:UBERON_0007311 a rdfs:Class ; rdfs:label "sputum" ; rdfs:comment "Matter ejected from the lungs, bronchi, and trachea, through the mouth." ; rdfs:subClassOf obo:UBERON_0006538 . obo:CIDO_0000943 a rdfs:Class ; rdfs:label "SARS-CoV2 nsp8 protein binding to human SEPSECS" ; rdfs:comment "SARS-CoV2 nsp8 protein binding to human SEPSECS, as evidented by an affinity-purification mass spectrometry experiment" ; rdfs:subClassOf obo:CIDO_0000582 . obo:NCBITaxon_31632 a rdfs:Class ; rdfs:label "Rat coronavirus" ; rdfs:subClassOf obo:NCBITaxon_694005 . obo:CHEBI_75954 a rdfs:Class ; rdfs:label "vancomycin aglycone zwitterion" ; rdfs:comment "A peptide zwitterion obtained by transfer of a proton from the carboxy to the amino group of vancomycin aglycone." ; rdfs:subClassOf obo:CHEBI_60466 . obo:CIDO_0000229 a rdfs:Class ; rdfs:label "enzyme activator role"@en ; rdfs:subClassOf obo:BFO_0000023 . obo:OAE_0000310 a rdfs:Class ; rdfs:label "dyspnea AE" ; rdfs:comment "An abnormal respiration AE that is characterized by a subjective experience of breathing discomfort that consists of qualitatively distinct sensations that vary in intensity." ; rdfs:subClassOf obo:OAE_0000571 . obo:CHEBI_189647 a rdfs:Class ; rdfs:label "AZ3451" ; rdfs:comment "A member of the class of benzimidazoles that is 1H-benzimidazole substituted by (1S)-1-cyclohexylethyl, 6-bromo-1,3-benzodioxol-5-yl, and 4-(cyanoanilino)acyl groups at positions 1, 2 and 5, respectively. It is an allosteric modulator of protease-activated receptor 2 (IC50 = 23 nM) and exhibits anti-osteoarthritis properties." ; rdfs:subClassOf obo:CHEBI_140325 , obo:CHEBI_18379 , obo:CHEBI_22715 , obo:CHEBI_37141 , obo:CHEBI_38298 . obo:CHEBI_71633 a rdfs:Class ; rdfs:label "hydroxypyrazine" ; rdfs:comment "Any piperazine carrying one or more hydroxy substituents." ; rdfs:subClassOf obo:CHEBI_33822 , obo:CHEBI_38314 . obo:PR_000000001 a rdfs:Class ; rdfs:label "protein" ; rdfs:comment "An amino acid chain that is produced de novo by ribosome-mediated translation of a genetically-encoded mRNA, and any derivatives thereof." ; rdfs:subClassOf obo:CHEBI_16670 , obo:CHEBI_23367 . obo:CIDO_0000984 a rdfs:Class ; rdfs:label "SARS-CoV2 orf7a protein binding to human HEATR3" ; rdfs:comment "SARS-CoV2 orf7a protein binding to human HEATR3, as evidented by an affinity-purification mass spectrometry experiment" ; rdfs:subClassOf obo:CIDO_0000587 . obo:CHEBI_48318 a rdfs:Class ; rdfs:label "fragrance" ; rdfs:comment "A substance, extract, or preparation for diffusing or imparting an agreeable or attractive smell." ; rdfs:subClassOf obo:CHEBI_33232 . obo:CHEBI_33484 a rdfs:Class ; rdfs:label "chalcogen oxoacid" ; rdfs:subClassOf obo:CHEBI_24833 , obo:CHEBI_33304 . obo:CIDO_0000177 a rdfs:Class ; rdfs:label "coronaviral RNA synthesis"@en ; rdfs:comment "A coronavirus molecular interaction that results in the synthesis of the viral RNA." ; rdfs:subClassOf obo:CIDO_0000204 . a rdfs:Class ; rdfs:label "Guanine [Chemical/Ingredient]" ; rdfs:subClassOf . obo:CHEBI_32529 a rdfs:Class ; rdfs:label "histidinate(1-)" ; rdfs:subClassOf obo:CHEBI_33558 . obo:GO_0019216 a rdfs:Class ; rdfs:label "regulation of lipid metabolic process" ; rdfs:comment "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving lipids." ; rdfs:subClassOf obo:GO_0080090 . obo:CIDO_0020308 a rdfs:Class ; rdfs:label "ThermoFisher - Applied Biosystems TaqPath COVID-19 Combo Kit" ; rdfs:seeAlso ; rdfs:subClassOf obo:CIDO_0000454 . obo:PR_Q99640 a rdfs:Class ; rdfs:label "membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase (human)" ; rdfs:comment "A membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000012784 , obo:PR_000029067 . obo:CHEBI_20857 a rdfs:Class ; rdfs:label "C-glycosyl compound" ; rdfs:comment "A glycosyl compound arising formally from the elimination of water from a glycosidic hydroxy group and an H atom bound to a carbon atom, thus creating a C-C bond." ; rdfs:subClassOf obo:CHEBI_63161 , obo:CHEBI_63299 . obo:CIDO_0000504 a rdfs:Class ; rdfs:label "GNQTLFCNIMKFSDR" ; rdfs:comment "A coronavirus epitope that is part of some S protein from HCoV 229E composed of the following amino acids GNQTLFCNIMKFSDR" ; rdfs:subClassOf obo:CIDO_0000451 . obo:PR_000003032 a rdfs:Class ; rdfs:label "focal adhesion kinase 2" ; rdfs:comment "A focal adhesion kinase that is a translation product of the human PTK2B gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000003030 . obo:CHEBI_59777 a rdfs:Class ; rdfs:label "ketal" ; rdfs:comment "An acetal of formula R2C(OR)2 (R =/= H) derived from a ketone by replacement of the oxo group by two hydrocarbyloxy groups. The class name 'ketals', once abandoned by IUPAC, has been reinstated as a subclass of acetals." ; rdfs:subClassOf obo:CHEBI_59769 . obo:NCBITaxon_903600 a rdfs:Class ; rdfs:label "Kenya bat coronavirus BtKY62" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:DOID_599 a rdfs:Class ; rdfs:label "specific phobia" ; rdfs:comment "A phobic disorder that is characterized by an unreasonable or irrational fear related to exposure to specific objects or situations." ; rdfs:subClassOf obo:DOID_591 . obo:CIDO_0020114 a rdfs:Class ; rdfs:label "Diatherix Eurofins Laboratory SARS-CoV-2 PCR Test" ; rdfs:seeAlso ; rdfs:subClassOf obo:CIDO_0000454 . a rdfs:Class ; rdfs:subClassOf obo:BFO_0000031 . obo:CHEBI_22927 a rdfs:Class ; rdfs:label "bromine atom" ; rdfs:subClassOf obo:CHEBI_24473 . obo:CHEBI_4781 a rdfs:Class ; rdfs:label "emetine" ; rdfs:comment "A pyridoisoquinoline comprising emetam having methoxy substituents at the 6'-, 7'-, 10- and 11-positions. It is an antiprotozoal agent and emetic. It inhibits SARS-CoV2, Zika and Ebola virus replication and displays antimalarial, antineoplastic and antiamoebic properties." ; rdfs:subClassOf obo:CHEBI_24921 , obo:CHEBI_61692 . obo:CHEBI_26432 a rdfs:Class ; rdfs:label "pyrimidine nucleobase" ; rdfs:comment "A nucleobase whose skeleton is derived from pyrimidine." ; rdfs:subClassOf obo:CHEBI_18282 , obo:CHEBI_39447 . obo:GO_0006401 a rdfs:Class ; rdfs:label "RNA catabolic process" ; rdfs:comment "The chemical reactions and pathways resulting in the breakdown of RNA, ribonucleic acid, one of the two main type of nucleic acid, consisting of a long, unbranched macromolecule formed from ribonucleotides joined in 3',5'-phosphodiester linkage." ; rdfs:subClassOf obo:GO_0016070 , obo:GO_0034655 , obo:GO_0044265 . obo:CHEBI_35381 a rdfs:Class ; rdfs:label "monosaccharide" ; rdfs:comment "Parent monosaccharides are polyhydroxy aldehydes H[CH(OH)]nC(=O)H or polyhydroxy ketones H-[CHOH]n-C(=O)[CHOH]m-H with three or more carbon atoms. The generic term 'monosaccharide' (as opposed to oligosaccharide or polysaccharide) denotes a single unit, without glycosidic connection to other such units. It includes aldoses, dialdoses, aldoketoses, ketoses and diketoses, as well as deoxy sugars, provided that the parent compound has a (potential) carbonyl group." ; rdfs:subClassOf obo:CHEBI_16646 . obo:PR_000003896 a rdfs:Class ; rdfs:label "A-kinase anchor protein 9" ; rdfs:comment "A protein that is a translation product of the human AKAP9 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:CIDO_0001100 a rdfs:Class ; rdfs:label "SARS-CoV2 orf8 protein binding to human INHBE"@en ; rdfs:comment "SARS-CoV2 orf8 protein binding to human INHBE, as evidented by an affinity-purification mass spectrometry experiment" ; rdfs:subClassOf obo:CIDO_0000051 . obo:NCBITaxon_1269295 a rdfs:Class ; rdfs:label "Coronavirus BtCoV/BRA118/Car_per/BRA/2009" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:PR_000003727 a rdfs:Class ; rdfs:label "a disintegrin and metalloproteinase with thrombospondin motifs 1" ; rdfs:comment "A protein that is a translation product of the human ADAMTS1 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . a rdfs:Class ; rdfs:label "Shock, Cardiogenic [Disease/Finding]" ; rdfs:subClassOf , . obo:CHEBI_83656 a rdfs:Class ; rdfs:label "luminespib" ; rdfs:comment "A monocarboxylic acid amide obtained by formal condensation of the carboxy group of 5-(2,4-dihydroxy-5-isopropylphenyl)-4-[4-(morpholin-4-ylmethyl)phenyl]-1,2-oxazole-3-carboxylic acid with the amino group of ethylamine." ; rdfs:subClassOf obo:CHEBI_29347 , obo:CHEBI_33572 , obo:CHEBI_38785 , obo:CHEBI_55373 , obo:CHEBI_62733 . obo:CIDO_0000693 a rdfs:Class ; rdfs:label "S373P in SARS-CoV-2 S protein" ; rdfs:comment "An AA mutation or AA variant that has mutated an amino acid at position 373 into a proline in S protein." ; rdfs:subClassOf obo:CIDO_0000593 . obo:VO_0005408 a rdfs:Class ; rdfs:label "EG-COVID"@en ; rdfs:comment "A SARS-CoV-2 RNA vaccine by EyeGene Inc." ; rdfs:subClassOf obo:VO_0005198 . obo:CHEBI_35346 a rdfs:Class ; rdfs:label "11beta-hydroxy steroid" ; rdfs:comment "Any 11-hydroxy steroid in which the hydroxy group at position 11 has beta- configuration." ; rdfs:subClassOf obo:CHEBI_36841 . obo:CIDO_0000577 a rdfs:Class ; rdfs:label "YEMYVKWPWYVWLLI" ; rdfs:comment "A coronavirus epitope that is part of some S protein from HCoV HKU1 composed of the following amino acids YEMYVKWPWYVWLLI" ; rdfs:subClassOf obo:CIDO_0000450 . obo:OBI_0002648 a rdfs:Class ; rdfs:label "individual organism specimen" ; rdfs:comment "A specimen composed of an individual organism to be studied in an investigation." ; rdfs:subClassOf obo:OBI_0100051 . obo:VO_0005184 a rdfs:Class ; rdfs:label "COVID-19 aAPC vaccine"@en ; rdfs:comment "A SARS-CoV-2 recombinant vector vaccine employing the lentiviral vector system and developed by Shenzhen Geno-Immune Medical Institute." ; rdfs:subClassOf obo:VO_0005199 . obo:DOID_600 a rdfs:Class ; rdfs:label "animal phobia" ; rdfs:comment "A specific phobia that involves a fear caused by the presence or thought of a specific animal that poses little or no danger at all." ; rdfs:subClassOf obo:DOID_599 . obo:NCBITaxon_749416 a rdfs:Class ; rdfs:label "unclassified Avian coronavirus" ; rdfs:subClassOf obo:NCBITaxon_694014 . obo:HP_0002011 a rdfs:Class ; rdfs:label "Morphological central nervous system abnormality" ; rdfs:comment "A structural abnormality of the central nervous system." ; rdfs:subClassOf obo:HP_0012639 . obo:CHEBI_83813 a rdfs:Class ; rdfs:label "proteinogenic amino acid" ; rdfs:comment "Any of the 23 alpha-amino acids that are precursors to proteins, and are incorporated into proteins during translation. The group includes the 20 amino acids encoded by the nuclear genes of eukaryotes together with selenocysteine, pyrrolysine, and N-formylmethionine. Apart from glycine, which is non-chiral, all have L configuration." ; rdfs:subClassOf obo:CHEBI_33575 , obo:CHEBI_35352 . a rdfs:Class ; rdfs:label "Female Urogenital Diseases [Disease/Finding]" ; rdfs:subClassOf . obo:CIDO_0000977 a rdfs:Class ; rdfs:label "SARS-CoV2 orf3a protein binding to human TRIM59" ; rdfs:comment "SARS-CoV2 orf3a protein binding to human TRIM59, as evidented by an affinity-purification mass spectrometry experiment" ; rdfs:subClassOf obo:CIDO_0000584 . obo:OBI_0000274 a rdfs:Class ; rdfs:label "adding a material entity into a target"@en ; rdfs:comment "is a process with the objective to place a material entity bearing the 'material to be added role' into a material bearing the 'target of material addition role'."@en ; rdfs:subClassOf obo:OBI_0000652 . obo:VO_0005167 a rdfs:Class ; rdfs:label "Chinese Academy of Medical Sciences COVID-19 vaccine" ; rdfs:comment "A SARS-CoV-2 inactivated whole virus vaccine that is developed by the Chinese Academy of Medical Sciences ." ; rdfs:subClassOf obo:VO_0005201 , obo:VO_0005266 . obo:PR_O76074 a rdfs:Class ; rdfs:label "cGMP-specific 3',5'-cyclic phosphodiesterase (human)" ; rdfs:comment "A cGMP-specific 3',5'-cyclic phosphodiesterase that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000012477 , obo:PR_000029067 . obo:APOLLO_SV_00000472 a rdfs:Class ; rdfs:label "age-dependent fecundity reduction"@en ; rdfs:comment "A rate measurement datum that measures the percentage decrease per unit time (typically per day) in the number of offspring to which a female mosquito passes an infection with a particular pathogen (e.g., Wolbachia)."@en ; rdfs:subClassOf obo:OBI_0001554 . obo:PR_000017529 a rdfs:Class ; rdfs:label "protein YIF1A" ; rdfs:comment "A protein that is a translation product of the human YIF1A gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:GO_0043406 a rdfs:Class ; rdfs:label "positive regulation of MAP kinase activity" ; rdfs:comment "Any process that activates or increases the frequency, rate or extent of MAP kinase activity." ; rdfs:subClassOf obo:GO_0043410 , obo:GO_0071900 , obo:GO_0071902 . obo:NCBITaxon_983928 a rdfs:Class ; rdfs:label "Miniopterus bat coronavirus/Kenya/KY33/2006" ; rdfs:subClassOf obo:NCBITaxon_366617 . obo:CIDO_0000424 a rdfs:Class ; rdfs:label "COVID-19 diagnostic process"@en ; rdfs:comment "A diagnostic process for detecting coronavirus from a patient" ; rdfs:subClassOf obo:CIDO_0000423 . obo:OGMS_0000031 a rdfs:Class ; rdfs:label "disease" ; rdfs:comment "A disposition (i) to undergo pathological processes that (ii) exists in an organism because of one or more disorders in that organism."@en ; rdfs:subClassOf obo:BFO_0000016 . obo:CHEBI_35284 a rdfs:Class ; rdfs:label "ammonium betaine" ; rdfs:comment "Any neutral molecule having charge-separated forms with a quaternary ammonium atom which bears no hydrogen atoms and that is not adjacent to the anionic atom." ; rdfs:subClassOf obo:CHEBI_26469 , obo:CHEBI_35281 . obo:CHEBI_132943 a rdfs:Class ; rdfs:label "aspartate" ; rdfs:subClassOf obo:CHEBI_33558 , obo:CHEBI_35693 . obo:CHEBI_32952 a rdfs:Class ; rdfs:label "amine" ; rdfs:comment "A compound formally derived from ammonia by replacing one, two or three hydrogen atoms by hydrocarbyl groups." ; rdfs:subClassOf obo:CHEBI_50047 . a rdfs:Class ; rdfs:label "Heterocyclic Compounds, 1-Ring [Chemical/Ingredient]" ; rdfs:subClassOf . obo:PR_P08173 a rdfs:Class ; rdfs:label "muscarinic acetylcholine receptor M4 (human)" ; rdfs:comment "A muscarinic acetylcholine receptor M4 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000001616 , obo:PR_000029067 . obo:OBI_0000671 a rdfs:Class ; rdfs:label "sample from organism" ; rdfs:comment "a material obtained from an organism in order to be a representative of the whole" ; rdfs:subClassOf obo:OBI_0000747 , obo:OBI_0001479 . obo:NCBITaxon_681883 a rdfs:Class ; rdfs:label "Kenya bat coronavirus BtKY40" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:PR_O43633 a rdfs:Class ; rdfs:label "charged multivesicular body protein 2a (human)" ; rdfs:comment "A charged multivesicular body protein 2a that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000005434 , obo:PR_000029067 . a rdfs:Class ; rdfs:label "Fascioloidiasis [Disease/Finding]" ; rdfs:subClassOf , . obo:NCBITaxon_11129 a rdfs:Class ; rdfs:label "Bovine coronavirus strain F15" ; rdfs:subClassOf obo:NCBITaxon_11128 . obo:CHEBI_36885 a rdfs:Class ; rdfs:label "20-oxo steroid" ; rdfs:comment "An oxo steroid carrying an oxo group at position 20." ; rdfs:subClassOf obo:CHEBI_35789 . obo:CHEBI_38355 a rdfs:Class ; rdfs:label "hex-4-enoic acid" ; rdfs:comment "A hexenoic acid with the double bond at position 4." ; rdfs:subClassOf obo:CHEBI_24580 . obo:APOLLO_SV_00000191 a rdfs:Class ; rdfs:label "transmission coefficient"@en ; rdfs:comment "An information content entity that represents the rate that an infection moves from infected individuals to susceptible individuals in a population."@en ; rdfs:subClassOf obo:OBI_0001554 . obo:GO_0033036 a rdfs:Class ; rdfs:label "macromolecule localization" ; rdfs:comment "Any process in which a macromolecule is transported to, or maintained in, a specific location." ; rdfs:subClassOf obo:GO_0051179 . obo:CIDO_0020103 a rdfs:Class ; rdfs:label "CRL Rapid Response" ; rdfs:seeAlso ; rdfs:subClassOf obo:CIDO_0000454 . obo:CHEBI_33708 a rdfs:Class ; rdfs:label "amino-acid residue" ; rdfs:comment "When two or more amino acids combine to form a peptide, the elements of water are removed, and what remains of each amino acid is called an amino-acid residue." ; rdfs:subClassOf obo:CHEBI_33247 . obo:CIDO_0000364 a rdfs:Class ; rdfs:label "severe COVID-19 disease process"@en ; rdfs:subClassOf obo:CIDO_0000003 . obo:CIDO_0000222 a rdf:Property ; rdfs:label "disease susceptibly severe with comorbidity"@en ; rdfs:comment "An object property that represents a relation between a disease process and a phenotype comorbidity where the disease (e.g., COVID-19 disease process) with the comorbidity is likely to have more severe outcome." ; rdfs:range . obo:CIDO_0000173 a rdf:Property ; rdfs:label "disease process susceptibly has phenotype"@en ; rdfs:comment "An object property that represents a relation between a disease process and its susceptibility of inducing a phenotype outcome" ; rdfs:range . obo:BFO_0000066 a rdf:Property ; rdfs:label "occurs in"@en ; rdfs:comment "b occurs_in c =def b is a process and c is a material entity or immaterial entity& there exists a spatiotemporal region r and b occupies_spatiotemporal_region r.& forall(t) if b exists_at t then c exists_at t & there exist spatial regions s and s’ where & b spatially_projects_onto s at t& c is occupies_spatial_region s’ at t& s is a proper_continuant_part_of s’ at t"@en ; rdfs:range . obo:VO_0005231 a rdfs:Class ; rdfs:label "COVIGEN"@en ; rdfs:comment "A SARS-CoV-2 DNA vaccine manufactured by University of Sydney, Bionet Co., and Technovalia" ; rdfs:subClassOf obo:VO_0005203 . obo:NCBITaxon_1541206 a rdfs:Class ; rdfs:label "Bat Hp-betacoronavirus/Zhejiang2013-1" ; rdfs:subClassOf obo:NCBITaxon_696098 . obo:DOID_850 a rdfs:Class ; rdfs:label "lung disease" ; rdfs:comment "A lower respiratory tract disease in which the function of the lungs is adversely affected by narrowing or blockage of the airways resulting in poor air flow, a loss of elasticity in the lungs that produces a decrease in the total volume of air that the lungs are able to hold, and clotting, scarring, or inflammation of the blood vessels that affect the ability of the lungs to take up oxygen and to release carbon dioxide." ; rdfs:subClassOf obo:DOID_0050161 . obo:DRON_00046109 a rdfs:Class ; rdfs:label "Tamoxifen 20 MG Oral Tablet" ; rdfs:subClassOf obo:DRON_00023504 . obo:VO_0005112 a rdfs:Class ; rdfs:label "Inactivated whole MERS-CoV (IV) vaccine with CpG and Alum" ; rdfs:comment "A MERS inactivated whole virus vaccine that has a combined adjuvant that has a combined adjuvant of aluminum hydroxide and CpG oligodeoxynucleotides." ; rdfs:subClassOf obo:VO_0004900 . obo:CIDO_0000111 a rdfs:Class ; rdfs:label "modulation of host response to coronaviral infection"@en ; rdfs:comment "A process that modulates host response to coronaviral infection" ; rdfs:subClassOf obo:CIDO_0000087 , obo:CIDO_0000110 . obo:CHEBI_7989 a rdfs:Class ; rdfs:label "pepstatin A" ; rdfs:comment "A pentapeptide isolated from Streptomyces testaceus. It is a potent inhibitor of aspartyl proteases." ; rdfs:subClassOf obo:CHEBI_140325 , obo:CHEBI_48545 . obo:PR_000002092 a rdfs:Class ; rdfs:label "signal transducer and activator of transcription 5b" ; rdfs:comment "A signal transducer and transcription activator STAT that is a translation product of the human STAT5B gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000001933 . obo:CIDO_0020057 a rdfs:Class ; rdfs:label "BioGX SARS-CoV-2 Reagents for BD MAX System" ; rdfs:seeAlso ; rdfs:subClassOf obo:CIDO_0000454 . obo:CIDO_0000483 a rdfs:Class ; rdfs:label "CQFKDKNLQDLWVLY" ; rdfs:comment "A coronavirus epitope that is part of some S protein from HCoV OC43 composed of the following amino acids CQFKDKNLQDLWVLY" ; rdfs:subClassOf obo:CIDO_0000452 . obo:NCBITaxon_1897076 a rdfs:Class ; rdfs:label "Bat coronavirus Mol.ruf/92/BRA/2013" ; rdfs:subClassOf obo:NCBITaxon_366617 . obo:PR_000001778 a rdfs:Class ; rdfs:label "inhibitor of nuclear factor kappa-B kinase subunit epsilon" ; rdfs:comment "An IKK-related kinase that is a translation product of the human IKBKE gene or a 1:1 ortholog thereof. Members of this class are part of the PMA-inducible IkappaB kinase complex." ; rdfs:subClassOf obo:PR_000001777 . obo:PR_000014647 a rdfs:Class ; rdfs:label "O-phosphoseryl-tRNA(Sec) selenium transferase" ; rdfs:comment "A protein that is a translation product of the human SEPSECS gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:PR_P29274 a rdfs:Class ; rdfs:label "adenosine receptor A2a (human)" ; rdfs:comment "An adenosine receptor A2a that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000001576 , obo:PR_000029067 . obo:PATO_0002146 a rdfs:Class ; rdfs:label "virulence"@en ; rdfs:comment "A quality inhering in a bearer by virtue of the bearer's pathogenicity."@en ; rdfs:subClassOf obo:PATO_0001995 . obo:CHEBI_77733 a rdfs:Class ; rdfs:label "2-(3,4-dimethoxyphenyl)-5-{[2-(3,4-dimethoxyphenyl)ethyl](methyl)amino}-2-(propan-2-yl)pentanenitrile" ; rdfs:comment "A tertiary amino compound that is 3,4-dimethoxyphenylethylamine in which the hydrogens attached to the nitrogen are replaced by a methyl group and a 4-cyano-4-(3,4-dimethoxyphenyl)-5-methylhexyl group." ; rdfs:subClassOf obo:CHEBI_18379 , obo:CHEBI_35618 , obo:CHEBI_46774 , obo:CHEBI_50996 . a rdfs:Class ; rdfs:label "Pasteurellaceae Infections [Disease/Finding]" ; rdfs:subClassOf . obo:CHEBI_180654 a rdfs:Class ; rdfs:label "N(4)-hydroxycytidine" ; rdfs:comment "A nucleoside analogue that is cytidine which carries a hydroxy group at the N(4)-positon. It has broad-spectrum antiviral activity against influenza, SARS-CoV , SARS-CoV-2 and MERS-CoV." ; rdfs:subClassOf obo:CHEBI_24983 , obo:CHEBI_60783 . obo:GO_0042493 a rdfs:Class . a rdfs:Class ; rdfs:label "ASTEMIZOLE" ; rdfs:subClassOf . obo:VO_0000179 a rdfs:Class ; rdfs:label "vaccine component" ; rdfs:comment "a processed material that is output of the vaccine preparation and part of a vaccine." ; rdfs:subClassOf obo:BFO_0000040 . a rdfs:Class ; rdfs:label "Hemostatic Disorders [Disease/Finding]" ; rdfs:subClassOf , . obo:CIDO_0020154 a rdfs:Class ; rdfs:label "Genus SARS-CoV-2 Assay" ; rdfs:seeAlso ; rdfs:subClassOf obo:CIDO_0000454 . obo:OGG_0000000010 a rdfs:Class ; rdfs:label "protein-coding gene disposition"@en ; rdfs:comment "a gene disposition that a gene can be used as a blueprint for generating a protein (i.e., a gene encodes for a protein). " ; rdfs:subClassOf obo:OGG_0000000003 . obo:CHEBI_48593 a rdfs:Class ; rdfs:label "benzocycloheptapyridine" ; rdfs:subClassOf obo:CHEBI_26979 , obo:CHEBI_38101 . obo:PR_000011211 a rdfs:Class ; rdfs:label "serine/threonine-protein kinase NIM1" ; rdfs:comment "A protein that is a translation product of the human NIM1K gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:CHEBI_32216 a rdfs:Class ; rdfs:label "thiethylperazine maleate" ; rdfs:subClassOf obo:CHEBI_50221 . obo:PR_000014207 a rdfs:Class ; rdfs:label "60S ribosomal protein L26-like 1" ; rdfs:comment "A protein that is a translation product of the human RPL26L1 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:PR_000004713 a rdfs:Class ; rdfs:label "mitochondrial chaperone BCS1" ; rdfs:comment "A protein that is a translation product of the human BCS1L gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:UBERON_0012275 a rdfs:Class ; rdfs:label "meso-epithelium" ; rdfs:comment "Epithelium that derives from the mesoderm. [Automatically generated definition]." ; rdfs:subClassOf obo:UBERON_0000483 , obo:UBERON_0004120 . obo:PR_000013685 a rdfs:Class ; rdfs:label "mRNA export factor RAE1" ; rdfs:comment "A protein that is a translation product of the human RAE1 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:NCBITaxon_643398 a rdfs:Class ; rdfs:label "Coronavirus red knot/p60/2006/GBR" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:NCBITaxon_745738 a rdfs:Class ; rdfs:label "Coronavirus M.das/VM7/2007/NLD" ; rdfs:subClassOf obo:NCBITaxon_696098 . obo:VO_0005104 a rdfs:Class ; rdfs:label "Recombinant SARS spike polypeptide vaccine" ; rdfs:comment "A SARS DNA vaccine that is made from intraperitoneal recombinant spike polypeptide generated by amplififying gene encoding amino acids residues 14-667 of S protein that was cloned BamHI and KpnI sites of vector pQE-31 that was generated by Escherichia coli" ; rdfs:subClassOf obo:VO_0012183 . a rdfs:Class ; rdfs:label "DNA Replication Alteration [PE]" ; rdfs:subClassOf . obo:VO_0005083 a rdfs:Class ; rdfs:label "CIGB-669"@en ; rdfs:comment "A SARS-CoV-2 protein subunit vaccine based on recombinant RBD subunits manufactured by the Center for Genetic Engineering and Biotechnology (CIGB)." ; rdfs:subClassOf obo:VO_0005202 . a rdfs:Class ; rdfs:label "Decreased Norepinephrine Activity [PE]" ; rdfs:subClassOf . obo:CHEBI_83317 a rdfs:Class ; rdfs:label "sterol biosynthesis inhibitor" ; rdfs:comment "Any compound that inhibits the biosynthesis of any sterol." ; rdfs:subClassOf obo:CHEBI_35222 , obo:CHEBI_52206 . obo:PR_000001861 a rdfs:Class ; rdfs:label "integrin beta" ; rdfs:comment "A protein with core architecture consisting of a large extracellular region containing one Integrin, beta chain domain (Pfam:PF00362), up to four EGF-like domains (Pfam:PF07974), and an Integrin beta tail domain (Pfam:PF07965), followed by a single-pass transmembrane region and a small cytoplasmic region often containing an Integrin beta cytoplasmic domain (Pfam:PF08725)." ; rdfs:subClassOf obo:PR_000000001 . obo:PR_P55789 a rdfs:Class ; rdfs:label "FAD-linked sulfhydryl oxidase ALR (human)" ; rdfs:comment "An FAD-linked sulfhydryl oxidase ALR that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000007940 , obo:PR_000029067 . obo:CHEBI_77166 a rdfs:Class ; rdfs:label "3-oxo-Delta(1),Delta(4)-steroid" ; rdfs:comment "A 3-oxo-Delta(1) steroid containing an additional double bond between positions 4 and 5." ; rdfs:subClassOf obo:CHEBI_20156 , obo:CHEBI_47909 . obo:PR_000001160 a rdfs:Class ; rdfs:label "Toll-like receptor 9" ; rdfs:comment "A Toll-like receptor that is a translation product of the human TLR9 gene or a 1:1 ortholog thereof. Non-methylated CpG motifs, present in viral and bacterial DNA, are one of many pathogen-associated molecular patterns (PAMP) recognized by the mammalian innate immune system. Recognition of this PAMP occurs through a specific interaction with Toll-like receptor 9 and this interaction can induce cytokine responses that influence both innate and adaptive immune responses." ; rdfs:subClassOf obo:PR_000001096 . obo:CHEBI_25905 a rdfs:Class ; rdfs:label "peptide hormone" ; rdfs:comment "Any peptide with hormonal activity in animals, whether endocrine, neuroendocrine, or paracrine." ; rdfs:subClassOf obo:CHEBI_16670 . obo:CIDO_0000003 a rdfs:Class ; rdfs:label "COVID-19 disease process" ; rdfs:comment "a coronavirus disease process that is induced by SARS-CoV-2" ; rdfs:subClassOf obo:CIDO_0000001 . obo:NCBITaxon_2042642 a rdfs:Class ; rdfs:label "Kenya bat coronavirus BtKY33/2006" ; rdfs:subClassOf obo:NCBITaxon_366617 . obo:PR_Q12866 a rdfs:Class ; rdfs:label "tyrosine-protein kinase Mer (human)" ; rdfs:comment "A tyrosine-protein kinase Mer that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000010329 , obo:PR_000029067 . obo:NCBITaxon_11140 a rdfs:Class ; rdfs:label "Murine hepatitis virus strain 3" ; rdfs:subClassOf obo:NCBITaxon_11138 . obo:CHEBI_28001 a rdfs:Class ; rdfs:label "vancomycin" ; rdfs:comment "A complex glycopeptide from Streptomyces orientalis. It inhibits a specific step in the synthesis of the peptidoglycan layer in the Gram-positive bacteria Staphylococcus aureus and Clostridium difficile." ; rdfs:subClassOf obo:CHEBI_24396 . obo:CHEBI_71019 a rdfs:Class ; rdfs:label "omacetaxine mepesuccinate" ; rdfs:comment "A cephalotaxine-derived alkaloid ester obtained from Cephalotaxus harringtonia; used for the treatment of chronic or accelerated phase chronic myeloid leukaemia." ; rdfs:subClassOf obo:CHEBI_26878 , obo:CHEBI_38164 , obo:CHEBI_38481 , obo:CHEBI_47985 . obo:NCBITaxon_2509477 a rdfs:Class ; rdfs:label "Colacovirus" ; rdfs:subClassOf obo:NCBITaxon_693996 . obo:PR_Q15569 a rdfs:Class ; rdfs:label "dual specificity testis-specific protein kinase 1 (human)" ; rdfs:comment "A dual specificity testis-specific protein kinase 1 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000016241 , obo:PR_000029067 . obo:CHEBI_50995 a rdfs:Class ; rdfs:label "secondary amino compound" ; rdfs:comment "A compound formally derived from ammonia by replacing two hydrogen atoms by organyl groups." ; rdfs:subClassOf obo:CHEBI_50047 . obo:NCBITaxon_1269309 a rdfs:Class ; rdfs:label "Coronavirus BtCoV/KCR372/Car_per/CRC/2010" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:OAE_0000063 a rdfs:Class ; rdfs:label "systematic AE" ; rdfs:comment "an adverse event that occurs systematically throughout the systemic circulation. This is different from local adverse event that is limited or a certain location." ; rdfs:subClassOf obo:OAE_0000001 . a rdfs:Class ; rdfs:label "Immunologically Active Molecule Degradation Alteration [PE]" ; rdfs:subClassOf . obo:CHEBI_35508 a rdfs:Class ; rdfs:label "steroid fundamental parent" ; rdfs:subClassOf obo:CHEBI_35341 , obo:CHEBI_35507 . obo:VO_0005263 a rdfs:Class ; rdfs:label "CoV2-OGEN1"@en ; rdfs:comment "A SARS-CoV-2 subunit vaccine that is orally administered and manufactured by Syneos Health" ; rdfs:subClassOf obo:VO_0005202 . obo:GO_0008285 a rdfs:Class ; rdfs:label "negative regulation of cell population proliferation" ; rdfs:comment "Any process that stops, prevents or reduces the rate or extent of cell proliferation." ; rdfs:subClassOf obo:GO_0042127 , obo:GO_0048523 . obo:HP_0011974 a rdfs:Class ; rdfs:label "Myelofibrosis" ; rdfs:comment "Replacement of bone marrow by fibrous tissue." ; rdfs:subClassOf obo:HP_0001871 . obo:NCBITaxon_1346300 a rdfs:Class ; rdfs:label "Betacoronavirus BtCoV/Rhi_fer/FR0711-B11/FRA/2011" ; rdfs:subClassOf obo:NCBITaxon_696098 . obo:PR_000025846 a rdfs:Class ; rdfs:label "fatty acid-binding protein" ; rdfs:comment "A protein that consists solely of the Lipocalin / cytosolic fatty-acid binding protein family domain (Pfam:PF00061)." ; rdfs:subClassOf obo:PR_000000001 . obo:UBERON_0006538 a rdfs:Class ; rdfs:label "respiratory system fluid/secretion" ; rdfs:comment "A portion of organism substance that secreted_by a respiratory system." ; rdfs:subClassOf obo:UBERON_0000463 . a rdfs:Class ; rdfs:label "Pyridinium Compounds [Chemical/Ingredient]" ; rdfs:subClassOf . obo:CIDO_0000925 a rdfs:Class ; rdfs:label "SARS-CoV2 nsp8 protein binding to human CCDC86" ; rdfs:comment "SARS-CoV2 nsp8 protein binding to human CCDC86, as evidented by an affinity-purification mass spectrometry experiment" ; rdfs:subClassOf obo:CIDO_0000582 . obo:CIDO_0000872 a rdfs:Class ; rdfs:label "SARS-CoV2 nsp2 protein binding to human POR" ; rdfs:comment "SARS-CoV2 nsp2 protein binding to human POR, as evidented by an affinity-purification mass spectrometry experiment" ; rdfs:subClassOf obo:CIDO_0000580 . obo:PR_P29597 a rdfs:Class ; rdfs:label "non-receptor tyrosine-protein kinase TYK2 (human)" ; rdfs:comment "A non-receptor tyrosine-protein kinase TYK2 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000016874 , obo:PR_000029067 . a rdfs:Class ; rdfs:label "Decreased Immunologic Activity [PE]" ; rdfs:subClassOf . obo:OBI_0302893 a rdfs:Class ; rdfs:label "storage"@en ; rdfs:comment "A maintenance process by which material entities that are not actively metabolizing are placed in well identified location and possibly under controlled environment in ad-hoc devices/structures in order to preserve and protect them from decay/alteration and maintain availability"@en ; rdfs:subClassOf obo:OBI_0000838 . obo:PR_P49760 a rdfs:Class ; rdfs:label "dual specificity protein kinase CLK2 (human)" ; rdfs:comment "A dual specificity protein kinase CLK2 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000005585 , obo:PR_000029067 . obo:CIDO_0000838 a rdfs:Class ; rdfs:label "SARS-CoV2 nsp13 protein binding to human GCC1" ; rdfs:comment "SARS-CoV2 nsp13 protein binding to human GCC1, as evidented by an affinity-purification mass spectrometry experiment" ; rdfs:subClassOf obo:CIDO_0000058 . a rdfs:Class ; rdfs:label "Serotonin Uptake Inhibitors [MoA]" ; rdfs:subClassOf . a rdfs:Class ; rdfs:label "Neurobehavioral Manifestations [Disease/Finding]" ; rdfs:subClassOf , . obo:CHEBI_18379 a rdfs:Class ; rdfs:label "nitrile" ; rdfs:comment "A compound having the structure RC#N; thus a C-substituted derivative of hydrocyanic acid, HC#N. In systematic nomenclature, the suffix nitrile denotes the triply bound #N atom, not the carbon atom attached to it." ; rdfs:subClassOf obo:CHEBI_23424 . obo:CHEBI_25413 a rdfs:Class ; rdfs:label "monounsaturated fatty acid" ; rdfs:comment "Any fatty acid with one double or triple bond in the fatty acid chain and singly bonded carbon atoms in the rest of the chain. MUFAs have positive effects on the cardiovascular system, and in diabetes treatment." ; rdfs:subClassOf obo:CHEBI_27208 . obo:VO_0005178 a rdfs:Class ; rdfs:label "adenovirus serotype 26 vaccine vector"@en ; rdfs:subClassOf obo:VO_0000136 . obo:CHEBI_35472 a rdfs:Class ; rdfs:label "anti-inflammatory drug" ; rdfs:comment "A substance that reduces or suppresses inflammation." ; rdfs:subClassOf obo:CHEBI_23888 , obo:CHEBI_67079 . obo:PR_Q9P289 a rdfs:Class ; rdfs:label "serine/threonine-protein kinase 26 (human)" ; rdfs:comment "A serine/threonine-protein kinase 26 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000002351 , obo:PR_000029067 . a rdfs:Class ; rdfs:label "Prednisolone [Chemical/Ingredient]" ; rdfs:subClassOf . obo:NCBITaxon_422218 a rdfs:Class ; rdfs:label "Bovine coronavirus E-AH65-TC" ; rdfs:subClassOf obo:NCBITaxon_422217 . obo:PR_000004435 a rdfs:Class ; rdfs:label "sodium/potassium-transporting ATPase subunit alpha-1" ; rdfs:comment "A protein that is a translation product of the human ATP1A1 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:PR_000017318 a rdfs:Class ; rdfs:label "vacuolar protein sorting-associated protein 11" ; rdfs:comment "A protein that is a translation product of the human VPS11 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:CHEBI_16670 a rdfs:Class ; rdfs:label "peptide" ; rdfs:comment "Amide derived from two or more amino carboxylic acid molecules (the same or different) by formation of a covalent bond from the carbonyl carbon of one to the nitrogen atom of another with formal loss of water. The term is usually applied to structures formed from alpha-amino acids, but it includes those derived from any amino carboxylic acid. X = OH, OR, NH2, NHR, etc." ; rdfs:subClassOf obo:CHEBI_33839 , obo:CHEBI_37622 , obo:CHEBI_50047 . obo:PR_P0DTC6 a rdfs:Class ; rdfs:label "ORF6 protein (SARS-CoV-2)" ; rdfs:comment "A protein that is a translation product of the ORF6 gene in SARS-CoV-2." ; rdfs:subClassOf obo:PR_000050262 . obo:CIDO_0000883 a rdfs:Class ; rdfs:label "SARS-CoV2 nsp4 protein binding to human TIMM9" ; rdfs:comment "SARS-CoV2 nsp4 protein binding to human TIMM9, as evidented by an affinity-purification mass spectrometry experiment" ; rdfs:subClassOf obo:CIDO_0000581 . a rdfs:Class ; rdfs:label "Adenocarcinoma [Disease/Finding]" ; rdfs:subClassOf . obo:PR_000012702 a rdfs:Class ; rdfs:label "GPI ethanolamine phosphate transferase 3" ; rdfs:comment "A protein that is a translation product of the human PIGO gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:NCBITaxon_285947 a rdfs:Class ; rdfs:label "SARS coronavirus civet014" ; rdfs:subClassOf obo:NCBITaxon_694009 . a rdfs:Class ; rdfs:label "Thiothixene [Chemical/Ingredient]" ; rdfs:subClassOf . a rdfs:Class ; rdfs:label "Neuromuscular Diseases [Disease/Finding]" ; rdfs:subClassOf . obo:CHEBI_55346 a rdfs:Class ; rdfs:label "anidulafungin" ; rdfs:comment "A semisynthetic echinocandin anti-fungal drug. It is active against Aspergillus and Candida species and is used for the treatment of invasive candidiasis." ; rdfs:subClassOf obo:CHEBI_24533 , obo:CHEBI_52898 , obo:CHEBI_57248 , obo:CHEBI_72588 , obo:CHEBI_87113 . obo:CHEBI_37622 a rdfs:Class ; rdfs:label "carboxamide" ; rdfs:comment "An amide of a carboxylic acid, having the structure RC(=O)NR2. The term is used as a suffix in systematic name formation to denote the -C(=O)NH2 group including its carbon atom." ; rdfs:subClassOf obo:CHEBI_33256 , obo:CHEBI_35352 , obo:CHEBI_36963 . a rdfs:Class ; rdfs:label "Histamine H1 Receptor Antagonists [MoA]" ; rdfs:subClassOf . obo:PR_P11233 a rdfs:Class ; rdfs:label "Ras-related protein Ral-A (human)" ; rdfs:comment "A Ras-related protein Ral-A that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000013695 , obo:PR_000029067 . obo:PR_000000006 a rdfs:Class ; rdfs:label "TGF-beta superfamily receptor type-1" ; rdfs:comment "A protein that is a translation product of an evolutionary-related gene with core domain composition consisting of an extracellular Activin types I and II receptor domain (Pfam:PF01064), a transmembrane domain, a Transforming growth factor beta type I GS-motif (Pfam:PF08515) and a Protein kinase domain (Pfam:PF00069). The transforming growth factor-beta (TGF-beta) superfamily of receptors comprises two groups of transmembrane serine-threonine kinase receptors, so called type-1, and type-2 receptors, that are activated following engagement by members of the TGF-beta superfamily of ligands. These events specify diverse downstream responses that are differentially regulated by controlling access and activation of the ligands, their receptors and downstream substrates in different cell types. The type 1 receptors are characterized by the presence of a glycine-serine rich juxta-membrane domain (the GS-motif) that is critical for their activation." ; rdfs:subClassOf obo:PR_000000001 . obo:NCBITaxon_1503284 a rdfs:Class ; rdfs:label "BtMf-AlphaCoV/HeN2013-a" ; rdfs:subClassOf obo:NCBITaxon_366617 . obo:GO_0007194 a rdfs:Class ; rdfs:label "negative regulation of adenylate cyclase activity" ; rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of adenylate cyclase activity." ; rdfs:subClassOf obo:GO_0031280 , obo:GO_0045761 , obo:GO_0051350 . obo:OBI_0002546 a rdfs:Class ; rdfs:label "liver specimen" ; rdfs:comment "A specimen that is derived from liver." ; rdfs:subClassOf obo:OBI_0001479 . obo:CHEBI_51060 a rdfs:Class ; rdfs:label "hormone agonist" ; rdfs:comment "A chemical substance which binds to specific hormone receptors activating the function of the endocrine glands, the biosynthesis of their secreted hormones, or the action of hormones upon their specific sites." ; rdfs:subClassOf obo:CHEBI_48705 , obo:CHEBI_51061 . obo:CIDO_0020189 a rdfs:Class ; rdfs:label "Logix Smart Coronavirus COVID-19" ; rdfs:seeAlso ; rdfs:subClassOf obo:CIDO_0000454 . obo:CIDO_0000234 a rdfs:Class ; rdfs:label "SARS-CoV-2 clade GH virus"@en ; rdfs:comment "A SARS-CoV-2 clade G variant virus that has signature mutations in Spike D614G and ORF3a Q57H." ; rdfs:subClassOf obo:CIDO_0000232 . obo:CHEBI_76711 a rdfs:Class ; rdfs:label "EC 4.1.* (C-C lyase) inhibitor" ; rdfs:comment "A lyase inhibitor which inhibits the action of a C-C lyase (EC 4.1.*.*)." ; rdfs:subClassOf obo:CHEBI_76710 . obo:CHEBI_22934 a rdfs:Class ; rdfs:label "bufanolide" ; rdfs:subClassOf obo:CHEBI_26766 , obo:CHEBI_35508 . obo:PR_000010139 a rdfs:Class ; rdfs:label "mitogen-activated protein kinase kinase kinase 6" ; rdfs:comment "A protein that is a translation product of the human MAP3K6 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . a rdfs:Class ; rdfs:label "Signs and Symptoms, Digestive [Disease/Finding]" ; rdfs:subClassOf . obo:CHEBI_35259 a rdfs:Class ; rdfs:label "benzofurans" ; rdfs:subClassOf obo:CHEBI_38104 , obo:CHEBI_38166 . obo:CHEBI_84232 a rdfs:Class ; rdfs:label "thienotriazolodiazepine" ; rdfs:comment "Any organic heterotricyclic compound constructed from fused thiophene, triazole and diazepeine rings." ; rdfs:subClassOf obo:CHEBI_26979 , obo:CHEBI_38101 , obo:CHEBI_38106 . obo:NCBITaxon_2042644 a rdfs:Class ; rdfs:label "Alphacoronavirus Trinidad/1FY2BA/2007" ; rdfs:subClassOf obo:NCBITaxon_366617 . obo:PR_000002240 a rdfs:Class ; rdfs:label "tyrosine-protein kinase Tec" ; rdfs:comment "A TEC-type tyrosine-protein kinase that is a translation product of the human TEC gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000001967 . a rdfs:Class ; rdfs:label "nitazoxanide [Chemical/Ingredient]" ; rdfs:subClassOf . obo:PR_000006047 a rdfs:Class ; rdfs:label "cullin-2" ; rdfs:comment "A cullin that is a translation product of the human CUL2 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000013 . obo:OAE_0004524 a rdfs:Class ; rdfs:label "injection site erythema AE"@en ; rdfs:comment "an injection-site AE that displays erythema at the injection site." ; rdfs:subClassOf obo:OAE_0000366 , obo:OAE_0000645 . obo:PR_P0DTD2 a rdfs:Class ; rdfs:label "ORF9b protein (SARS-CoV-2)" ; rdfs:comment "A protein that is a translation product of the ORF9b gene in SARS-CoV-2." ; rdfs:subClassOf obo:PR_000050262 . obo:CHEBI_64577 a rdfs:Class ; rdfs:label "flour treatment agent" ; rdfs:comment "A food additive which is added to flour or dough to improve baking quality and/or colour." ; rdfs:subClassOf obo:CHEBI_64047 . a rdfs:Class ; rdfs:label "CHLORPROMAZINE HYDROCHLORIDE" ; rdfs:subClassOf . obo:CHEBI_189650 a rdfs:Class ; rdfs:label "Ternatin 4 (DA3)" ; rdfs:subClassOf obo:CHEBI_50860 . a rdfs:Class ; rdfs:label "Cetylpyridinium [Chemical/Ingredient]" ; rdfs:subClassOf . obo:NCBITaxon_1868640 a rdfs:Class ; rdfs:label "Bat coronavirus/4705/2013/Cynomops abrasus/Brazil" ; rdfs:subClassOf obo:NCBITaxon_366617 . a rdfs:Class ; rdfs:label "Cellular Cycle Alteration [PE]" ; rdfs:subClassOf . obo:PR_000001201 a rdfs:Class ; rdfs:label "C-C chemokine receptor type 5" ; rdfs:comment "A chemokine receptor that is a translation product of the human CCR5 gene or a 1:1 ortholog thereof. The preferred ligands include CCL3, CCL4, CCL5, CCL8, CCL14." ; rdfs:subClassOf obo:PR_000001128 . obo:CIDO_0000649 a rdfs:Class ; rdfs:label "P314L in SARS-CoV-2 pp1b protein" ; rdfs:comment "An AA mutation or AA variant that has mutated an amino acid at position 314 into a leucine in pp1b." ; rdfs:subClassOf obo:CIDO_0000715 . obo:CIDO_0001201 a rdfs:Class ; rdfs:label "Multiple Real-Time PCR Kit for Detection of 2019-nCoV. (Zhejiang Orient Gene Biotech Co., Ltd)" ; rdfs:comment "Scope of application/Intended use: This kit is used for qualitative detection of the ORF1ab and N genes of SARS-CoV-2 RNA." ; rdfs:subClassOf obo:CIDO_0000021 . obo:PR_000007743 a rdfs:Class ; rdfs:label "Ras GTPase-activating protein-binding protein 1" ; rdfs:comment "A protein that is a translation product of the human G3BP1 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:NCBITaxon_2249315 a rdfs:Class ; rdfs:label "Quail deltacoronavirus" ; rdfs:subClassOf obo:NCBITaxon_2724161 . obo:NCBITaxon_1288689 a rdfs:Class ; rdfs:label "Bat coronavirus POA/2012/132" ; rdfs:subClassOf obo:NCBITaxon_366617 . obo:NCBITaxon_2042579 a rdfs:Class ; rdfs:label "Coronavirus PREDICT CoV-55" ; rdfs:subClassOf obo:NCBITaxon_696098 . obo:PR_000016828 a rdfs:Class ; rdfs:label "gamma-tubulin complex component 3" ; rdfs:comment "A protein that is a translation product of the human TUBGCP3 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:PR_Q9NXK8 a rdfs:Class ; rdfs:label "F-box/LRR-repeat protein 12 (human)" ; rdfs:comment "An F-box/LRR-repeat protein 12 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000007370 , obo:PR_000029067 . obo:UBERON_0036149 a rdfs:Class ; rdfs:label "suprapubic skin" ; rdfs:comment "Area of skin in the hypoastric region of the abdomen." ; rdfs:subClassOf obo:UBERON_0000465 . obo:PR_000010863 a rdfs:Class ; rdfs:label "myosin-IIIa" ; rdfs:comment "A protein that is a translation product of the human MYO3A gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . a rdfs:Class ; rdfs:label "Digestive System Diseases [Disease/Finding]" ; rdfs:subClassOf . obo:NCBITaxon_228330 a rdfs:Class ; rdfs:label "SARS coronavirus Urbani" ; rdfs:subClassOf obo:NCBITaxon_694009 . obo:GO_0042220 a rdfs:Class ; rdfs:label "response to cocaine" ; rdfs:comment "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cocaine stimulus. Cocaine is a crystalline alkaloid obtained from the leaves of the coca plant." ; rdfs:subClassOf obo:GO_0014070 , obo:GO_0043279 , obo:GO_1901700 . obo:CHEBI_35243 a rdfs:Class ; rdfs:label "serine zwitterion" ; rdfs:comment "An amino acid zwitterion obtained by transfer of a proton from the carboxy to the amnio group of serine." ; rdfs:subClassOf obo:CHEBI_35238 . obo:CIDO_0000846 a rdfs:Class ; rdfs:label "SARS-CoV2 nsp13 protein binding to human HSBP1" ; rdfs:comment "SARS-CoV2 nsp13 protein binding to human HSBP1, as evidented by an affinity-purification mass spectrometry experiment" ; rdfs:subClassOf obo:CIDO_0000058 . obo:UBERON_0000995 a rdfs:Class ; rdfs:label "uterus" ; rdfs:comment "the female muscular organ of gestation in which the developing embryo or fetus is nourished until birth" ; rdfs:subClassOf obo:UBERON_0000465 . obo:GO_0007187 a rdfs:Class ; rdfs:label "G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger" ; rdfs:comment "A G protein-coupled receptor signaling pathway in which the signal is transmitted via the activation or inhibition of a nucleotide cyclase activity and a subsequent change in the concentration of a cyclic nucleotide." ; rdfs:subClassOf obo:GO_0007186 . obo:GO_0071310 a rdfs:Class ; rdfs:label "cellular response to organic substance" ; rdfs:comment "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an organic substance stimulus." ; rdfs:subClassOf obo:GO_0010033 , obo:GO_0070887 . obo:VO_0005162 a rdfs:Class ; rdfs:label "ZyCoV-D" ; rdfs:comment "A SARS-CoV-2 plasmid DNA vaccine that encodes the envelope protein." ; rdfs:subClassOf obo:VO_0005323 . obo:CHEBI_29919 a rdfs:Class ; rdfs:label "hydrosulfide" ; rdfs:subClassOf obo:CHEBI_33535 . obo:CHEBI_27848 a rdfs:Class ; rdfs:label "alpha-L-rhamnoside" ; rdfs:subClassOf obo:CHEBI_26547 . obo:OAE_0003692 a rdfs:Class ; rdfs:label "Grade 3 myocarditis AE" ; rdfs:comment "a myocarditis AE that has severe with symptoms at rest or with minimal activity or exertion; intervention indicated" ; rdfs:subClassOf obo:OAE_0001201 . obo:NCBITaxon_694015 a rdfs:Class ; rdfs:label "Beluga whale coronavirus SW1" ; rdfs:subClassOf obo:NCBITaxon_2509476 . a rdfs:Class ; rdfs:label "Encephalitis, Viral [Disease/Finding]" ; rdfs:subClassOf . obo:CIDO_0000965 a rdfs:Class ; rdfs:label "SARS-CoV2 orf10 protein binding to human ELOC" ; rdfs:comment "SARS-CoV2 orf10 protein binding to human ELOC, as evidented by an affinity-purification mass spectrometry experiment" ; rdfs:subClassOf obo:CIDO_0000050 . obo:PR_000007489 a rdfs:Class ; rdfs:label "fibroblast growth factor 2" ; rdfs:comment "A protein that is a translation product of the human FGF2 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:PR_000014282 a rdfs:Class ; rdfs:label "ribosomal protein S6 kinase alpha-1" ; rdfs:comment "A ribosomal protein S6 kinase alpha that is a translation product of the human RPS6KA1 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000029187 . obo:CIDO_0020042 a rdfs:Class ; rdfs:label "BD SARS-CoV-2/Flu for BD MAX System" ; rdfs:seeAlso ; rdfs:subClassOf obo:CIDO_0000454 . obo:CHEBI_189681 a rdfs:Class ; rdfs:label "mitochondrial ribosomes" ; rdfs:comment "a protein complex that is active in mitochondria and functions as a riboprotein for translating mitochondrial mRNAs encoded in mtDNA" ; rdfs:subClassOf obo:CHEBI_50860 . obo:CIDO_0000689 a rdfs:Class ; rdfs:label "Q954H in SARS-CoV-2 S protein" ; rdfs:comment "An AA mutation or AA variant that has mutated an amino acid at position 954 into a histidine in S protein." ; rdfs:subClassOf obo:CIDO_0001162 . obo:HP_0010535 a rdfs:Class ; rdfs:label "Sleep apnea" ; rdfs:comment "An intermittent cessation of airflow at the mouth and nose during sleep. Apneas of at least 10 seconds are considered important, but persons with sleep apnea may have apneas of 20 seconds to up to 2 or 3 minutes. Patients may have up to 15 events per hour of sleep." ; rdfs:subClassOf obo:HP_0002360 , obo:HP_0002795 . obo:CHEBI_71666 a rdfs:Class ; rdfs:label "gamma-amino acid anion" ; rdfs:comment "An amino-acid anion in which the amino group is situated gamma- to the carboxylate group." ; rdfs:subClassOf obo:CHEBI_37022 . obo:CIDO_0001046 a rdfs:Class ; rdfs:label "SARS-CoV2 orf9c protein binding to human ALG8" ; rdfs:comment "SARS-CoV2 orf9c protein binding to human ALG8, as evidented by an affinity-purification mass spectrometry experiment" ; rdfs:subClassOf obo:CIDO_0000054 . obo:HP_0100659 a rdfs:Class ; rdfs:label "Abnormality of the cerebral vasculature" ; rdfs:comment "An anomaly of the cerebral blood vessels." ; rdfs:subClassOf obo:HP_0002597 , obo:HP_0012443 . obo:NCBITaxon_502106 a rdfs:Class ; rdfs:label "Murine coronavirus MHV-1" ; rdfs:subClassOf obo:NCBITaxon_11138 . obo:CIDO_0001014 a rdfs:Class ; rdfs:label "Bamlanivimab" ; rdfs:subClassOf obo:CHEBI_23367 . obo:NCBITaxon_249079 a rdfs:Class ; rdfs:label "SARS coronavirus HSZ-Bc" ; rdfs:subClassOf obo:NCBITaxon_694009 . a rdfs:Class ; rdfs:label "Hypereosinophilic Syndrome [Disease/Finding]" ; rdfs:subClassOf . obo:GO_0032774 a rdfs:Class ; rdfs:label "RNA biosynthetic process" ; rdfs:comment "The chemical reactions and pathways resulting in the formation of RNA, ribonucleic acid, one of the two main type of nucleic acid, consisting of a long, unbranched macromolecule formed from ribonucleotides joined in 3',5'-phosphodiester linkage. Includes polymerization of ribonucleotide monomers. Refers not only to transcription but also to e.g. viral RNA replication." ; rdfs:subClassOf obo:GO_0009059 , obo:GO_0016070 , obo:GO_0034654 . obo:HP_0006684 a rdfs:Class ; rdfs:label "Ventricular preexcitation with multiple accessory pathways" ; rdfs:comment "A form of ventricular preexcitation due to the presence of multiple accessory pathways for cardiac conduction." ; rdfs:subClassOf obo:HP_0004309 . obo:CHEBI_33552 a rdfs:Class ; rdfs:label "sulfonic acid derivative" ; rdfs:subClassOf obo:CHEBI_33424 . obo:CHEBI_60606 a rdfs:Class ; rdfs:label "opioid receptor agonist" ; rdfs:comment "An agent that selectively binds to and activates an opioid receptor." ; rdfs:subClassOf obo:CHEBI_48705 , obo:CHEBI_60598 . a rdfs:Class ; rdfs:label "Decreased GI Motility [PE]" ; rdfs:subClassOf . obo:NCBITaxon_903586 a rdfs:Class ; rdfs:label "Kenya bat coronavirus BtKY48" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:CIDO_0000522 a rdfs:Class ; rdfs:label "LFVVALFIGVSFIDY" ; rdfs:comment "A coronavirus epitope that is part of some S protein from HCoV NL63 composed of the following amino acids LFVVALFIGVSFIDY" ; rdfs:subClassOf obo:CIDO_0000449 . obo:OBI_2000018 a rdfs:Class ; rdfs:label "leukocyte specimen" ; rdfs:comment "A specimen that is derived from some leukocytes" ; rdfs:subClassOf obo:OBI_0002599 . obo:PR_Q06418 a rdfs:Class ; rdfs:label "tyrosine-protein kinase receptor TYRO3 (human)" ; rdfs:comment "A tyrosine-protein kinase receptor TYRO3 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000016878 , obo:PR_000029067 . obo:PR_000016677 a rdfs:Class ; rdfs:label "N(2),N(2)-dimethylguanosine tRNA methyltransferase" ; rdfs:comment "A protein that is a translation product of the human TRMT1 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:CHEBI_33641 a rdfs:Class ; rdfs:label "olefin" ; rdfs:comment "Acyclic and cyclic hydrocarbons having one or more carbon-carbon double bonds, apart from the formal ones in aromatic compounds. The class olefins subsumes alkenes and cycloalkenes and the corresponding polyenes." ; rdfs:subClassOf obo:CHEBI_24632 , obo:CHEBI_78840 . obo:NCBITaxon_742002 a rdfs:Class ; rdfs:label "Bat SARS coronavirus HKU3-5" ; rdfs:subClassOf obo:NCBITaxon_442736 . obo:VO_0005139 a rdfs:Class ; rdfs:label "rSARS-CoV-ΔE vaccine" ; rdfs:comment "A SARS recombinant vector vaccine made from a line attenuated and recombinant SARS-CoV lacking the E gene" ; rdfs:subClassOf obo:VO_0012183 . obo:NCBITaxon_2664421 a rdfs:Class ; rdfs:label "Bat coronavirus 512" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:CIDO_0020159 a rdfs:Class ; rdfs:label "Gravity Diagnostics COVID-19 Assay" ; rdfs:seeAlso ; rdfs:subClassOf obo:CIDO_0000454 . obo:CHEBI_24231 a rdfs:Class ; rdfs:label "geranylgeranyl group" ; rdfs:subClassOf obo:CHEBI_26201 . obo:CHEBI_27207 a rdfs:Class ; rdfs:label "univalent carboacyl group" ; rdfs:comment "A univalent carboacyl group is a group formed by loss of OH from the carboxy group of a carboxylic acid." ; rdfs:subClassOf obo:CHEBI_37838 . obo:VO_0004989 a rdfs:Class ; rdfs:label "S protein of SARS-CoV-2"@en . obo:NCBITaxon_267384 a rdfs:Class ; rdfs:label "SARS coronavirus Sin852" ; rdfs:subClassOf obo:NCBITaxon_694009 . obo:CHEBI_32637 a rdfs:Class ; rdfs:label "D-methioninate" ; rdfs:comment "The D-enantiomer of methioninate." ; rdfs:subClassOf obo:CHEBI_32644 . obo:CHEBI_84135 a rdfs:Class ; rdfs:label "L-serine derivative" ; rdfs:comment "A proteinogenic amino acid derivative resulting from reaction of L-serine at the amino group or the carboxy group, or from the replacement of any hydrogen of L-serine by a heteroatom." ; rdfs:subClassOf obo:CHEBI_26649 , obo:CHEBI_83811 . obo:PR_000001497 a rdfs:Class ; rdfs:label "opioid receptor protein" ; rdfs:comment "A rhodopsin-like G-protein coupled receptor that is a translation product of the human OPRD1, OPRK1, OPRM1, or OPRL1 genes, 1:1 orthologs thereof, or a semi-ortholog thereof." ; rdfs:subClassOf obo:PR_000001094 . obo:NCBITaxon_1644139 a rdfs:Class ; rdfs:label "Bat coronavirus BEM003F" ; rdfs:subClassOf obo:NCBITaxon_696098 . obo:APOLLO_SV_00000445 a rdfs:Class ; rdfs:label "mortality rate"@en ; rdfs:comment "A rate measurement datum that specifies the percentage of organisms within a population that have died over a given time interval."@en ; rdfs:subClassOf obo:OBI_0001554 . obo:OPMI_0000534 a rdfs:Class ; rdfs:label "medical condition stop reason specification"@en ; rdfs:comment "An action specification that indicates why a Condition is no longer valid with respect to the purpose specified within the source data." ; rdfs:subClassOf obo:IAO_0000007 . obo:CIDO_0020054 a rdfs:Class ; rdfs:label "BioFire COVID-19 test" ; rdfs:seeAlso ; rdfs:subClassOf obo:CIDO_0000454 . obo:CIDO_0020196 a rdfs:Class ; rdfs:label "Lyra SARS-CoV-2 Assay" ; rdfs:subClassOf obo:CIDO_0000454 . obo:NCBITaxon_8504 a rdfs:Class ; rdfs:label "Lepidosauria" ; rdfs:subClassOf obo:NCBITaxon_32561 . obo:PR_000031980 a rdfs:Class ; rdfs:label "tripartite motif-containing protein 59" ; rdfs:comment "A tripartite motif-containing protein that is a translation product of the human TRIM59 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000044733 . obo:CHEBI_33229 a rdfs:Class ; rdfs:label "vitamin (role)" ; rdfs:comment "A biochemical role played by any micronutrient that is an organic compound. Vitamins are present in foods in small amounts and are essential to normal metabolism and biochemical functions, usually as coenzymes. The term \"vitamines\" (from vita + amines) was coined in 1912 by Casimir Funk, who believed that these compounds were amines." ; rdfs:subClassOf obo:CHEBI_27027 , obo:CHEBI_52206 . obo:CIDO_0020319 a rdfs:Class ; rdfs:label "Verily COVID-19 RT-PCR Test" ; rdfs:seeAlso ; rdfs:subClassOf obo:CIDO_0000454 . obo:NCBITaxon_1920748 a rdfs:Class ; rdfs:label "NL63-related bat coronavirus" ; rdfs:subClassOf obo:NCBITaxon_2501929 . a rdfs:Class ; rdfs:label "4-Hydroxycoumarins [Chemical/Ingredient]" ; rdfs:subClassOf . obo:DRON_00024057 a rdfs:Class ; rdfs:label "Hydroxyprogesterone Injectable Solution" ; rdfs:subClassOf obo:DRON_00000020 . obo:PR_000008568 a rdfs:Class ; rdfs:label "homeodomain-interacting protein kinase 3" ; rdfs:comment "A protein that is a translation product of the human HIPK3 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:PR_O94973 a rdfs:Class ; rdfs:label "AP-2 complex subunit alpha-2 (human)" ; rdfs:comment "An AP-2 complex subunit alpha-2 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000004100 , obo:PR_000029067 . obo:CIDO_0000973 a rdfs:Class ; rdfs:label "SARS-CoV2 orf3a protein binding to human ARL6IP6" ; rdfs:comment "SARS-CoV2 orf3a protein binding to human ARL6IP6, as evidented by an affinity-purification mass spectrometry experiment" ; rdfs:subClassOf obo:CIDO_0000584 . obo:PR_000013635 a rdfs:Class ; rdfs:label "Ras-related protein Rab-5C" ; rdfs:comment "A protein that is a translation product of the human RAB5C gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:BFO_0000019 a rdfs:Class ; rdfs:label "quality"@en ; rdfs:subClassOf obo:BFO_0000020 . obo:CIDO_0020002 a rdfs:Class ; rdfs:label "Access IL-6" ; rdfs:subClassOf obo:CIDO_0000454 . obo:CHEBI_39446 a rdfs:Class ; rdfs:label "pyrimidine ribonucleosides" ; rdfs:subClassOf obo:CHEBI_18254 , obo:CHEBI_26440 . obo:VO_0005122 a rdfs:Class ; rdfs:label "MERS-CoV pcDNA3.1-S1 DNA vaccine" ; rdfs:comment "A MERS DNA vaccine made of plasmid that encodes the first 725 amino acids of S from MERS-CoV" ; rdfs:subClassOf obo:VO_0004900 . obo:CIDO_0000218 a rdfs:Class ; rdfs:label "hydrolysis of angiotensin II into angiotensin (1-7)"@en ; rdfs:comment "hydrolysis of angiotensin II into angiotensin (1-7) by ACE2" ; rdfs:subClassOf obo:GO_0016485 . obo:CHEBI_46766 a rdfs:Class ; rdfs:label "N-acylpyrrolidine" ; rdfs:subClassOf obo:CHEBI_32988 , obo:CHEBI_38260 . obo:GO_0009889 a rdfs:Class ; rdfs:label "regulation of biosynthetic process" ; rdfs:comment "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of substances." ; rdfs:subClassOf obo:GO_0019222 . obo:PR_000016168 a rdfs:Class ; rdfs:label "elongin-C" ; rdfs:comment "A protein that is a translation product of the human ELOC gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:PR_O60462 a rdfs:Class ; rdfs:label "neuropilin-2 (human)" ; rdfs:comment "A neuropilin-2 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000011436 , obo:PR_000029067 . obo:PR_000003043 a rdfs:Class ; rdfs:label "mitogen-activated protein kinase kinase kinase kinase 4" ; rdfs:comment "A protein that is a translation product of the human MAP4K4 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . a rdfs:Class ; rdfs:label "IMATINIB MESYLATE" ; rdfs:subClassOf . obo:PR_P16435 a rdfs:Class ; rdfs:label "NADPH--cytochrome P450 reductase (human)" ; rdfs:comment "An NADPH--cytochrome P450 reductase that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000013030 , obo:PR_000029067 . obo:OAE_0000406 a rdfs:Class ; rdfs:label "chest pain AE" ; rdfs:comment "a pain AE that occurs at the chest" ; rdfs:subClassOf obo:OAE_0000374 . obo:HP_0040068 a rdfs:Class ; rdfs:label "Abnormality of limb bone" ; rdfs:subClassOf obo:HP_0000924 , obo:HP_0040064 . obo:UBERON_0000057 a rdfs:Class ; rdfs:label "urethra" ; rdfs:comment "the fibromuscular tubular canal through which urine is discharged from the bladder to the exterior via the external urinary meatus; in males, the urethra is joined by the ejaculatory ducts and serves as a passageway for semen during ejaculation, as well as a canal for urine during voiding; in females, the urethra is shorter and emerges above the vaginal opening" ; rdfs:subClassOf obo:UBERON_0000465 . obo:CIDO_0000021 a rdfs:Class ; rdfs:label "NMPA authorized COVID-19 diagnostic testing device"@en ; rdfs:comment "a COVID-19 diagnostic testing device that is authorized by the National Medical Products Administratoin (NMPA) to use in China"@en ; rdfs:subClassOf obo:CIDO_0000453 . obo:GO_0006650 a rdfs:Class ; rdfs:label "glycerophospholipid metabolic process" ; rdfs:comment "The chemical reactions and pathways involving glycerophospholipids, any derivative of glycerophosphate that contains at least one O-acyl, O-alkyl, or O-alkenyl group attached to the glycerol residue." ; rdfs:subClassOf obo:GO_0006644 , obo:GO_0046486 . obo:VO_0001479 a rdfs:Class ; rdfs:label "vaccine target specification" ; rdfs:comment "The objective that intends to produce vaccine via the vaccine preparation process." ; rdfs:subClassOf obo:IAO_0000005 . obo:GO_0007200 a rdfs:Class ; rdfs:label "phospholipase C-activating G protein-coupled receptor signaling pathway" ; rdfs:comment "A G protein-coupled receptor signaling pathway in which the signal is transmitted via the activation of phospholipase C (PLC) and a subsequent increase in the intracellular concentration of inositol trisphosphate (IP3) and diacylglycerol (DAG)." ; rdfs:subClassOf obo:GO_0007186 . obo:CIDO_0020173 a rdfs:Class ; rdfs:label "Influenza SARS-CoV-2 (Flu SC2) Multiplex Assay" ; rdfs:seeAlso ; rdfs:subClassOf obo:CIDO_0000454 . obo:GO_0051272 a rdfs:Class ; rdfs:label "positive regulation of cellular component movement" ; rdfs:comment "Any process that activates or increases the frequency, rate or extent of the movement of a cellular component." ; rdfs:subClassOf obo:GO_0048522 , obo:GO_0051270 . a rdfs:Class ; rdfs:label "Carcinoma, Renal Cell [Disease/Finding]" ; rdfs:subClassOf , . obo:PR_O75964 a rdfs:Class ; rdfs:label "ATP synthase subunit g, mitochondrial (human)" ; rdfs:comment "An ATP synthase subunit g, mitochondrial that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000004463 , obo:PR_000029067 . obo:CIDO_0020210 a rdfs:Class ; rdfs:label "NeoPlex COVID-19 Detection Kit" ; rdfs:seeAlso ; rdfs:subClassOf obo:CIDO_0000454 . obo:PR_000013573 a rdfs:Class ; rdfs:label "serine/threonine-protein kinase QSK" ; rdfs:comment "A protein that is a translation product of the human SIK3 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:CHEBI_52267 a rdfs:Class ; rdfs:label "7-hydroxyflavonol" ; rdfs:comment "Any flavonol carrying a 7-hydroxy substituent." ; rdfs:subClassOf obo:CHEBI_28802 . obo:NCBITaxon_749434 a rdfs:Class ; rdfs:label "Rock sandpiper coronavirus CIR-65824" ; rdfs:subClassOf obo:NCBITaxon_749416 . obo:CIDO_0000954 a rdfs:Class ; rdfs:label "SARS-CoV2 nsp9 protein binding to human MIB1" ; rdfs:comment "SARS-CoV2 nsp9 protein binding to human MIB1, as evidented by an affinity-purification mass spectrometry experiment" ; rdfs:subClassOf obo:CIDO_0000583 . obo:OBI_0000434 a rdfs:Class ; rdfs:label "adding material objective"@en ; rdfs:comment "is the specification of an objective to add a material into a target material. The adding is asymmetric in the sense that the target material largely retains its identity"@en ; rdfs:subClassOf obo:OBI_0000686 . obo:VO_0005250 a rdfs:Class ; rdfs:label "KD-414"@en ; rdfs:comment "A SARS-CoV-2 inactivated vaccine developed by KM Biologics Co., Ltd." ; rdfs:subClassOf obo:VO_0005201 . obo:GO_1901699 a rdfs:Class ; rdfs:label "cellular response to nitrogen compound" ; rdfs:comment "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nitrogen compound stimulus." ; rdfs:subClassOf obo:GO_0070887 , obo:GO_1901698 . obo:NCBITaxon_2801855 a rdfs:Class ; rdfs:label "Bat coronavirus RacCS271" ; rdfs:subClassOf obo:NCBITaxon_1986197 . obo:CIDO_0000461 a rdfs:Class ; rdfs:label "APYGLLFMHFSYKPI" ; rdfs:comment "A coronavirus epitope that is part of some S protein from HCoV HKU1 composed of the following amino acids APYGLLFMHFSYKPI" ; rdfs:subClassOf obo:CIDO_0000409 . obo:CHEBI_51453 a rdfs:Class ; rdfs:label "(S)-carnitinium" ; rdfs:comment "A carnitinium that is the conjugate acid of (S)-carnitine." ; rdfs:subClassOf obo:CHEBI_3424 . obo:OPMI_0000580 a rdfs:Class ; rdfs:label "measurement date"@en ; rdfs:comment "A date when a measurement is conducted." ; rdfs:subClassOf obo:OPMI_0000579 . obo:CHEBI_50903 a rdfs:Class ; rdfs:label "carcinogenic agent" ; rdfs:comment "A role played by a chemical compound which is known to induce a process of carcinogenesis by corrupting normal cellular pathways, leading to the acquistion of tumoral capabilities." ; rdfs:subClassOf obo:CHEBI_52209 . obo:CIDO_0020136 a rdfs:Class ; rdfs:label "Exact Sciences LaboratoriesSARS-CoV-2 Test" ; rdfs:seeAlso ; rdfs:subClassOf obo:CIDO_0000454 . obo:GO_0023056 a rdfs:Class ; rdfs:label "positive regulation of signaling" ; rdfs:comment "Any process that activates, maintains or increases the frequency, rate or extent of a signaling process." ; rdfs:subClassOf obo:GO_0023051 , obo:GO_0048518 . obo:CIDO_0001111 a rdfs:Class ; rdfs:label "SARS-CoV2 orf9b protein binding to human MARK1"@en ; rdfs:comment "SARS-CoV2 orf9b protein binding to human MARK1, as evidented by an affinity-purification mass spectrometry experiment" ; rdfs:subClassOf obo:CIDO_0000052 . obo:PR_000004866 a rdfs:Class ; rdfs:label "eIF5-mimic protein 1" ; rdfs:comment "A protein that is a translation product of the human BZW2 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:PR_000015751 a rdfs:Class ; rdfs:label "serine/threonine-protein kinase 33" ; rdfs:comment "A protein that is a translation product of the human STK33 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . a rdfs:Class ; rdfs:label "HEXACHLOROPHENE" ; rdfs:subClassOf . obo:OPMI_0000545 a rdfs:Class ; rdfs:label "referral diagnosis status"@en ; rdfs:comment "A referral is a written request from one health professional to another health professional or health service, asking them to diagnose or treat you for a particular condition." ; rdfs:subClassOf obo:OPMI_0000533 . obo:DRON_00000006 a rdfs:Class ; rdfs:label "portion of mixture"@en ; rdfs:comment "a material entity that contains two or more scattered object aggregates as its only parts, where the grains of each object aggregate are of different types and evenly distributed throughout, such that any two parts of the entity, each of which is spatially contiguous and of the same size, contain nearly equal numbers of grains of the aggregates"@en ; rdfs:subClassOf obo:BFO_0000030 . obo:PR_000012825 a rdfs:Class ; rdfs:label "tissue-type plasminogen activator" ; rdfs:comment "A protein that is a translation product of the human PLAT gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:GO_0043550 a rdfs:Class ; rdfs:label "regulation of lipid kinase activity" ; rdfs:comment "Any process that modulates the frequency, rate or extent of lipid kinase activity, the catalysis of the transfer of a phosphate group, usually from ATP, to a simple or complex lipid." ; rdfs:subClassOf obo:GO_0043549 . obo:PR_Q2T9J0 a rdfs:Class ; rdfs:label "peroxisomal leader peptide-processing protease (human)" ; rdfs:comment "A peroxisomal leader peptide-processing protease that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000016881 , obo:PR_000029067 . a rdfs:Class ; rdfs:label "Metabolic Activity Alteration [PE]" ; rdfs:subClassOf . obo:PR_000010518 a rdfs:Class ; rdfs:label "mannosyl-oligosaccharide glucosidase" ; rdfs:comment "A protein that is a translation product of the human MOGS gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:CIDO_0020121 a rdfs:Class ; rdfs:label "DSL COVID-19 Assay" ; rdfs:seeAlso ; rdfs:subClassOf obo:CIDO_0000454 . obo:PR_000003961 a rdfs:Class ; rdfs:label "polyunsaturated fatty acid 5-lipoxygenase" ; rdfs:comment "A protein that is a translation product of the human ALOX5 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:PR_Q07912 a rdfs:Class ; rdfs:label "activated CDC42 kinase 1 (human)" ; rdfs:comment "An activated CDC42 kinase 1 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000016496 , obo:PR_000029067 . obo:CIDO_0000346 a rdfs:Class ; rdfs:label "host molecular response to coronavirus"@en ; rdfs:comment "A host-coronavirus molecular interaction where the focus is the coronavirus process inside a host cell at the molecular level." ; rdfs:subClassOf obo:CIDO_0000087 , obo:CIDO_0000345 . a rdfs:Class ; rdfs:label "Inhibit Ovulation [PE]" ; rdfs:subClassOf . obo:GO_0009987 a rdfs:Class ; rdfs:label "cellular process" ; rdfs:comment "Any process that is carried out at the cellular level, but not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level." ; rdfs:subClassOf obo:GO_0008150 . obo:GO_0031326 a rdfs:Class ; rdfs:label "regulation of cellular biosynthetic process" ; rdfs:comment "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of substances, carried out by individual cells." ; rdfs:subClassOf obo:GO_0009889 , obo:GO_0031323 . obo:CHEBI_29969 a rdfs:Class ; rdfs:label "L-lysinium residue" ; rdfs:subClassOf obo:CHEBI_32579 , obo:CHEBI_33727 . obo:NCBITaxon_1503278 a rdfs:Class ; rdfs:label "BtMf-AlphaCoV/AH2011" ; rdfs:subClassOf obo:NCBITaxon_694000 . obo:OGG_3043740578 a rdfs:Class ; rdfs:label "ORF1ab of severe acute respiratory syndrome coronavirus 2" ; rdfs:subClassOf obo:OGG_2002697049 . obo:CHEBI_338412 a rdfs:Class ; rdfs:label "(-)-anisomycin" ; rdfs:comment "An antibiotic isolated from various Streptomyces species. It interferes with protein and DNA synthesis by inhibiting peptidyl transferase or the 80S ribosome system." ; rdfs:subClassOf obo:CHEBI_25558 , obo:CHEBI_46777 . obo:PR_000008853 a rdfs:Class ; rdfs:label "hypoxia up-regulated protein 1" ; rdfs:comment "A protein that is a translation product of the human HYOU1 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:CIDO_0000746 a rdfs:Class ; rdfs:label "D1183Y in SARS-CoV-2 pp1b protein"@en ; rdfs:comment "An AA variant that has mutated a pp1b amino acid at position 1183 into tyrosine." ; rdfs:subClassOf obo:CIDO_0001084 . obo:PR_P51692 a rdfs:Class ; rdfs:label "signal transducer and activator of transcription 5B (human)" ; rdfs:comment "A signal transducer and activator of transcription 5b that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000002092 , obo:PR_000029067 . obo:CIDO_0020277 a rdfs:Class ; rdfs:label "SARS-CoV-2 RBD IgG test" ; rdfs:seeAlso ; rdfs:subClassOf obo:CIDO_0000454 . obo:NCBITaxon_267395 a rdfs:Class ; rdfs:label "SARS coronavirus Sin845" ; rdfs:subClassOf obo:NCBITaxon_694009 . obo:NCBITaxon_389244 a rdfs:Class ; rdfs:label "Bat coronavirus (BtCoV/A1018/2005)" ; rdfs:subClassOf obo:NCBITaxon_389126 . a rdfs:Class ; rdfs:label "Interferon Type I, Recombinant [Chemical/Ingredient]" ; rdfs:subClassOf , . obo:NCBITaxon_231422 a rdfs:Class ; rdfs:label "Bovine coronavirus strain Ontario" ; rdfs:subClassOf obo:NCBITaxon_11128 . obo:CHEBI_38527 a rdfs:Class ; rdfs:label "benzazepine alkaloid fundamental parent" ; rdfs:subClassOf obo:CHEBI_35506 . obo:CIDO_0000816 a rdfs:Class ; rdfs:label "SARS-CoV2 nsp12 protein binding to human TCF12" ; rdfs:comment "SARS-CoV2 nsp12 protein binding to human TCF12, as evidented by an affinity-purification mass spectrometry experiment" ; rdfs:subClassOf obo:CIDO_0000057 . obo:PR_P01563 a rdfs:Class ; rdfs:label "interferon alpha-2 (human)" ; rdfs:comment "An interferon alpha-2 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000008915 , obo:PR_000044694 . obo:CHEBI_51958 a rdfs:Class ; rdfs:label "organic polycyclic compound" ; rdfs:subClassOf obo:CHEBI_33635 , obo:CHEBI_33832 . obo:PR_Q10713 a rdfs:Class ; rdfs:label "mitochondrial-processing peptidase subunit alpha (human)" ; rdfs:comment "A mitochondrial-processing peptidase subunit alpha that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000012911 , obo:PR_000029067 . obo:NCBITaxon_1146860 a rdfs:Class ; rdfs:label "Bat coronavirus M.nattereri/UK/Wyt/1012B" ; rdfs:subClassOf obo:NCBITaxon_366617 . obo:VO_0004906 a rdfs:Class ; rdfs:label "MERS-CoV protein"@en ; rdfs:subClassOf obo:PR_000000001 , obo:VO_0010754 . obo:CIDO_0000491 a rdfs:Class ; rdfs:label "LIREIVMNASPYDLE" ; rdfs:comment "A coronavirus epitope that is part of some S protein from HCoV OC43 composed of the following amino acids LIREIVMNASPYDLE" ; rdfs:subClassOf obo:CIDO_0000452 . obo:PR_000001422 a rdfs:Class ; rdfs:label "histamine H1 receptor" ; rdfs:comment "A histamine receptor that is a translation product of the human HRH1 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000049994 . obo:CHEBI_9168 a rdfs:Class ; rdfs:label "sirolimus" ; rdfs:comment "A macrolide lactam isolated from Streptomyces hygroscopicus consisting of a 29-membered ring containing 4 trans double bonds, three of which are conjugated. It is an antibiotic, immunosupressive and antineoplastic agent." ; rdfs:subClassOf obo:CHEBI_145565 , obo:CHEBI_25698 , obo:CHEBI_26979 , obo:CHEBI_35681 , obo:CHEBI_3992 , obo:CHEBI_59770 , obo:CHEBI_87113 . obo:PR_Q8TBX8 a rdfs:Class ; rdfs:label "phosphatidylinositol 5-phosphate 4-kinase type-2 gamma (human)" ; rdfs:comment "A phosphatidylinositol 5-phosphate 4-kinase type-2 gamma that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000012743 , obo:PR_000029067 . obo:VO_0005115 a rdfs:Class ; rdfs:label "SARS Ad S/N vaccine" ; rdfs:comment "A SARS recombinant vector vaccine made of combination of two adenovirus-based vectors, one expressing the nucleocapsid (N) and the other expressing the spike (S) protein" ; rdfs:subClassOf obo:VO_0012183 . obo:CHEBI_16855 a rdfs:Class ; rdfs:label "D-lysine" ; rdfs:comment "The D-enantiomer of the alpha-amino acid lysine." ; rdfs:subClassOf obo:CHEBI_16733 , obo:CHEBI_25094 . obo:CHEBI_38631 a rdfs:Class ; rdfs:label "aminoalkylindole" ; rdfs:subClassOf obo:CHEBI_24828 . obo:OPMI_0000519 a rdfs:Class ; rdfs:label "provenance of episode record"@en ; rdfs:comment "A provenance of record that determines the provenance of the Episode record, as in whether the procedure was from an EHR system, insurance claim, registry, or other sources." ; rdfs:subClassOf obo:OPMI_0000512 . obo:NCBITaxon_264378 a rdfs:Class ; rdfs:label "SARS coronavirus TW-GD1" ; rdfs:subClassOf obo:NCBITaxon_264370 . obo:DRON_00013621 a rdfs:Class ; rdfs:label "Indinavir" ; rdfs:subClassOf obo:OBI_0000047 . obo:APOLLO_SV_00000229 a rdfs:Class ; rdfs:label "place closure control strategy"@en ; rdfs:comment "an infectious disease control strategy that has an action specification that is realized in closing facilities where organisms congregate during times when the facilities normally would be open."@en ; rdfs:subClassOf obo:APOLLO_SV_00000086 . a rdfs:Class ; rdfs:label "Acyclovir [Chemical/Ingredient]" ; rdfs:subClassOf . obo:CHEBI_22744 a rdfs:Class ; rdfs:label "benzyl group" ; rdfs:subClassOf obo:CHEBI_33452 , obo:CHEBI_50325 . obo:CIDO_0000267 a rdfs:Class ; rdfs:label "mast cell activation syndrome"@en ; rdfs:comment "Mast cell activation syndrome (MCAS) is one type of mast cell activation disorder (MCAD), and is an immunological condition in which mast cells inappropriately and excessively release chemical mediators, resulting in a range of chronic symptoms, sometimes including anaphylaxis or near-anaphylaxis attacks." ; rdfs:subClassOf obo:CIDO_0000268 . obo:VO_0005101 a rdfs:Class ; rdfs:label "SARS N + SARS M DNA vaccine" ; rdfs:comment "'A SARS DNA combination vaccine that is made from recombinant plasmids’ containing membrane protein (M) and nucleocapsid protein (N) sequences constructed then expressed and purified from E. coli bacteria’" ; rdfs:subClassOf obo:VO_0012183 . obo:CHEBI_32620 a rdfs:Class ; rdfs:label "L-leucinium" ; rdfs:comment "The L-enantiomer of leucinium." ; rdfs:subClassOf obo:CHEBI_32628 . obo:CHEBI_22888 a rdfs:Class ; rdfs:label "biphenyls" ; rdfs:comment "Benzenoid aromatic compounds containing two phenyl or substituted-phenyl groups which are joined together by a single bond." ; rdfs:subClassOf obo:CHEBI_33836 , obo:CHEBI_36820 , obo:CHEBI_64459 . obo:CHEBI_35493 a rdfs:Class ; rdfs:label "antipyretic" ; rdfs:comment "A drug that prevents or reduces fever by lowering the body temperature from a raised state. An antipyretic will not affect the normal body temperature if one does not have fever. Antipyretics cause the hypothalamus to override an interleukin-induced increase in temperature. The body will then work to lower the temperature and the result is a reduction in fever." ; rdfs:subClassOf obo:CHEBI_23888 . obo:CHEBI_46668 a rdfs:Class ; rdfs:label "amino acid ester" ; rdfs:comment "Any carboxylic ester derivative of an amino acid." ; rdfs:subClassOf obo:CHEBI_33308 , obo:CHEBI_83821 . obo:GO_0051179 a rdfs:Class ; rdfs:label "localization" ; rdfs:comment "Any process in which a cell, a substance, or a cellular entity, such as a protein complex or organelle, is transported, tethered to or otherwise maintained in a specific location. In the case of substances, localization may also be achieved via selective degradation." ; rdfs:subClassOf obo:GO_0008150 . obo:GO_0006873 a rdfs:Class ; rdfs:label "cellular ion homeostasis" ; rdfs:comment "Any process involved in the maintenance of an internal steady state of ions at the level of a cell." ; rdfs:subClassOf obo:GO_0050801 , obo:GO_0055082 . obo:PR_000000007 a rdfs:Class ; rdfs:label "TGF-beta superfamily receptor type-2 with activin receptor domain" ; rdfs:comment "A protein that is a translation product of an evolutionary-related gene with core domain composition consisting of an extracellular Activin types I and II receptor domain (Pfam:PF01064), a transmembrane domain, and a Protein kinase domain (Pfam:PF00069). The transforming growth factor-beta (TGF-beta) superfamily of receptors comprises two groups of transmembrane serine-threonine kinase receptors, so called type-1, and type-2 receptors, that are activated following engagement by members of the TGF-beta superfamily of ligands. These events specify diverse downstream responses that are differentially regulated by controlling access and activation of the ligands, their receptors and downstream substrates in different cell types." ; rdfs:subClassOf obo:PR_000000001 . obo:NCBITaxon_1415852 a rdfs:Class ; rdfs:label "Bat SARS-like coronavirus WIV1" ; rdfs:subClassOf obo:NCBITaxon_694009 . obo:CHEBI_35676 a rdfs:Class ; rdfs:label "benzazepine" ; rdfs:comment "A group of two-ring heterocyclic compounds consisting of a benzene ring fused to an azepine ring." ; rdfs:subClassOf obo:CHEBI_27171 , obo:CHEBI_38101 . a rdfs:Class ; rdfs:label "Salivation Inhibition [PE]" ; rdfs:subClassOf . obo:CIDO_0000701 a rdfs:Class ; rdfs:label "T547K in SARS-CoV-2 S protein" ; rdfs:comment "An AA mutation or AA variant that has mutated an amino acid at position 547 into a lysine in S protein." ; rdfs:subClassOf obo:CIDO_0000592 . obo:VariO_0002 a rdfs:Class ; rdfs:label "variation affecting protein" ; rdfs:comment "Effects of a variation on protein level." ; rdfs:subClassOf obo:VariO_0001 . obo:NCBITaxon_1699340 a rdfs:Class ; rdfs:label "Myotis Bat Alphacoronavirus strain YNXY_45C" ; rdfs:subClassOf obo:NCBITaxon_366617 . obo:PR_000004294 a rdfs:Class ; rdfs:label "ADP-ribosylation factor-like protein 6-interacting protein 6" ; rdfs:comment "A protein that is a translation product of the human ARL6IP6 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:GO_0031401 a rdfs:Class ; rdfs:label "positive regulation of protein modification process" ; rdfs:comment "Any process that activates or increases the frequency, rate or extent of the covalent alteration of one or more amino acid residues within a protein." ; rdfs:subClassOf obo:GO_0031399 , obo:GO_0032270 . obo:CHEBI_132124 a rdfs:Class ; rdfs:label "1,4-benzoquinones" ; rdfs:comment "Any member of the class of benzoquinones that is 1,4-benzoquinone or its C-substituted derivatives." ; rdfs:subClassOf obo:CHEBI_22729 , obo:CHEBI_25830 . obo:GO_0045321 a rdfs:Class ; rdfs:label "leukocyte activation" ; rdfs:comment "A change in morphology and behavior of a leukocyte resulting from exposure to a specific antigen, mitogen, cytokine, cellular ligand, or soluble factor." ; rdfs:subClassOf obo:GO_0001775 , obo:GO_0002376 . obo:VO_0011486 a rdfs:Class ; rdfs:label "SARS Subunit Spike Protein Vaccine" ; rdfs:subClassOf obo:VO_0012183 . obo:OAE_0000377 a rdfs:Class ; rdfs:label "headache AE" ; rdfs:comment "a pain AE that has an outcome of headache" ; rdfs:subClassOf obo:OAE_0000374 . obo:CHEBI_63471 a rdfs:Class ; rdfs:label "branched-chain amino-acid anion" ; rdfs:comment "A branched-chain amino acid whose alpha-carboxylic acid group is ionized (not protonated)." ; rdfs:subClassOf obo:CHEBI_37022 . obo:CHEBI_25699 a rdfs:Class ; rdfs:label "organic ion" ; rdfs:subClassOf obo:CHEBI_24870 , obo:CHEBI_50860 . obo:NCBITaxon_2591234 a rdfs:Class ; rdfs:label "Coronavirus BtRs-BetaCoV/YN2018A" ; rdfs:subClassOf obo:NCBITaxon_696098 . obo:CHEBI_75381 a rdfs:Class ; rdfs:label "EC 1.11.1.* (peroxidases) inhibitor" ; rdfs:comment "An EC 1.11.* (oxidoreductase acting on peroxide as donors) inhibitor that interferes with the action of any of the peroxidases (EC 1.11.1.*)." ; rdfs:subClassOf obo:CHEBI_76738 . obo:OPMI_0000559 a rdfs:Class ; rdfs:label "secondary admission diagnosis status"@en ; rdfs:subClassOf obo:OPMI_0000546 . obo:NCBITaxon_1476502 a rdfs:Class ; rdfs:label "Porcine deltacoronavirus 8734/USA-IA/2014" ; rdfs:subClassOf obo:NCBITaxon_1159905 . obo:PATO_0000383 a rdfs:Class ; rdfs:label "female" ; rdfs:comment "A biological sex quality inhering in an individual or a population that only produces gametes that can be fertilised by male gametes." ; rdfs:subClassOf obo:PATO_0001894 . obo:VO_0001503 a rdfs:Class ; rdfs:label "bovine coronavirus vaccine" ; rdfs:comment "viral vaccine that is used to protect against Bovine coronavirus infection" ; rdfs:subClassOf obo:VO_0004897 . a rdfs:Class ; rdfs:label "Uterine Neoplasms [Disease/Finding]" ; rdfs:subClassOf , . obo:GO_0015103 a rdfs:Class ; rdfs:label "inorganic anion transmembrane transporter activity" ; rdfs:comment "Enables the transfer of inorganic anions from one side of a membrane to the other. Inorganic anions are atoms or small molecules with a negative charge which do not contain carbon in covalent linkage." ; rdfs:subClassOf obo:GO_0015075 , obo:GO_0015318 . obo:NCBITaxon_2042553 a rdfs:Class ; rdfs:label "Coronavirus PREDICT CoV-27" ; rdfs:subClassOf obo:NCBITaxon_366617 . a rdfs:Class ; rdfs:label "Decreased Sympathetic Norepinephrine Activity [PE]" ; rdfs:subClassOf , . a rdfs:Class ; rdfs:label "Hepatitis, Viral, Human [Disease/Finding]" ; rdfs:subClassOf , obo:DOID_934 . obo:CIDO_0000335 a rdfs:Class ; rdfs:label "AQYTSALLAGTITSG"@en ; rdfs:subClassOf obo:CIDO_0000314 . a rdfs:Class ; rdfs:label "Helminthiasis, Animal [Disease/Finding]" ; rdfs:subClassOf , . obo:PR_P17948 a rdfs:Class ; rdfs:label "vascular endothelial growth factor receptor 1 (human)" ; rdfs:comment "A vascular endothelial growth factor receptor 1 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000007563 , obo:PR_000029067 . a rdfs:Class ; rdfs:label "Endocytosis Alteration [PE]" ; rdfs:subClassOf . obo:CIDO_0000914 a rdfs:Class ; rdfs:label "SARS-CoV2 nsp7 protein binding to human RAB5C" ; rdfs:comment "SARS-CoV2 nsp7 protein binding to human RAB5C, as evidented by an affinity-purification mass spectrometry experiment" ; rdfs:subClassOf obo:CIDO_0000049 . obo:CHEBI_24473 a rdfs:Class ; rdfs:label "halogen" ; rdfs:subClassOf obo:CHEBI_25585 , obo:CHEBI_33560 . obo:OBI_0002521 a rdfs:Class ; rdfs:label "renal medulla specimen" ; rdfs:comment "A specimen that is derived from renal medulla." ; rdfs:subClassOf obo:OBI_0001479 . obo:CHEBI_2979 a rdfs:Class ; rdfs:label "baicalein" ; rdfs:comment "A trihydroxyflavone with the hydroxy groups at positions C-5, -6 and -7." ; rdfs:subClassOf obo:CHEBI_27116 . a rdfs:Class ; rdfs:label "Neoplasms, Glandular and Epithelial [Disease/Finding]" ; rdfs:subClassOf . obo:NCBITaxon_2781647 a rdfs:Class ; rdfs:label "Avian coronavirus IA1162/2020" ; rdfs:subClassOf obo:NCBITaxon_749416 . a rdfs:Class ; rdfs:label "Interferon-alpha [Chemical/Ingredient]" ; rdfs:subClassOf . obo:PR_P03366 a rdfs:Class ; rdfs:label "gag-pol polyprotein (Human immunodeficiency virus type 1 group M subtype B (isolate BH10))" ; rdfs:comment "A lentivirus-type gag-pol polyprotein that is encoded in the genome of Human immunodeficiency virus type 1 group M subtype B (isolate BH10)." ; rdfs:subClassOf obo:PR_000036197 , obo:PR_000044455 . obo:CIDO_0000191 a rdfs:Class ; rdfs:label "methylation capping of coronaviral pre-mRNA"@en ; rdfs:subClassOf obo:CIDO_0000204 . obo:PR_000011406 a rdfs:Class ; rdfs:label "glucocorticoid receptor" ; rdfs:comment "A protein that is a translation product of the human NR3C1 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:CIDO_0000634 a rdfs:Class ; rdfs:label "F3677- in SARS-CoV-2 pp1a protein" ; rdfs:comment "An AA mutation or AA variant that has mutated an amino acid at position 3677 into a deletion" ; rdfs:subClassOf obo:CIDO_0001147 . obo:CIDO_0000827 a rdfs:Class ; rdfs:label "SARS-CoV2 nsp13 protein binding to human CEP112" ; rdfs:comment "SARS-CoV2 nsp13 protein binding to human CEP112, as evidented by an affinity-purification mass spectrometry experiment" ; rdfs:subClassOf obo:CIDO_0000058 . obo:CHEBI_82721 a rdfs:Class ; rdfs:label "dalbavancin" ; rdfs:comment "A semisynthetic glycopeptide used for the treatment of acute bacterial skin and skin structure infections caused or suspected to be caused by susceptible isolates of designated Gram-positive microorganisms including MRSA." ; rdfs:subClassOf obo:CHEBI_24396 , obo:CHEBI_63367 , obo:CHEBI_63436 , obo:CHEBI_72588 . obo:NCBITaxon_1699353 a rdfs:Class ; rdfs:label "Rousettus Bat Betacoronavirus strain ML_3I" ; rdfs:subClassOf obo:NCBITaxon_696098 . obo:OBCS_0000233 a rdfs:Class ; rdfs:label "transformed data item"@en ; rdfs:comment "A data item that is produced as the output of a data transformation." ; rdfs:subClassOf obo:IAO_0000027 . obo:HP_0012649 a rdfs:Class ; rdfs:label "Increased inflammatory response" ; rdfs:comment "A abnormal increase in the inflammatory response to injury or infection." ; rdfs:subClassOf obo:HP_0010978 . obo:PR_P53667 a rdfs:Class ; rdfs:label "LIM domain kinase 1 (human)" ; rdfs:comment "A LIM domain kinase 1 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000009816 , obo:PR_000029067 . obo:PR_P00367 a rdfs:Class ; rdfs:label "glutamate dehydrogenase 1, mitochondrial (human)" ; rdfs:comment "A glutamate dehydrogenase 1, mitochondrial that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000008056 , obo:PR_000029067 . obo:CHEBI_76837 a rdfs:Class ; rdfs:label "EC 1.13.11.* (oxidoreductase acting on single donors and incorporating 2 O atoms) inhibitor" ; rdfs:comment "An EC 1.13.* [oxidoreductase acting on single donors with incorporation of molecular oxygen (oxygenases)] inhibitor that inhibits the action of any oxidoreductase incorporating 2 atoms of oxygen (EC 1.13.11.*)." ; rdfs:subClassOf obo:CHEBI_76740 . obo:NCBITaxon_389251 a rdfs:Class ; rdfs:label "Bat coronavirus (BtCoV/A433/2005)" ; rdfs:subClassOf obo:NCBITaxon_389126 . obo:CIDO_0000806 a rdfs:Class ; rdfs:label "SARS-CoV2 nsp12 protein binding to human LARP4B" ; rdfs:comment "SARS-CoV2 nsp12 protein binding to human LARP4B, as evidented by an affinity-purification mass spectrometry experiment" ; rdfs:subClassOf obo:CIDO_0000057 . obo:GO_0097746 a rdfs:Class ; rdfs:label "blood vessel diameter maintenance" ; rdfs:comment "Any process that modulates the diameter of blood vessels." ; rdfs:subClassOf obo:GO_0003018 , obo:GO_0065008 . obo:CIDO_0020266 a rdfs:Class ; rdfs:label "Rutgers Clinical Genomics Laboratory TaqPath SARS-CoV-2-Assay" ; rdfs:seeAlso ; rdfs:subClassOf obo:CIDO_0000454 . obo:HP_0025439 a rdfs:Class ; rdfs:label "Pharyngitis"@en ; rdfs:comment "Inflammation (due to infection or irritation) of the pharynx." ; rdfs:subClassOf obo:HP_0033151 . obo:PR_Q92772 a rdfs:Class ; rdfs:label "cyclin-dependent kinase-like 2 (human)" ; rdfs:comment "A cyclin-dependent kinase-like 2 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000005270 , obo:PR_000029067 . obo:OBI_0002550 a rdfs:Class ; rdfs:label "sigmoid colon specimen" ; rdfs:comment "A specimen that is derived from sigmoid colon." ; rdfs:subClassOf obo:OBI_0001479 . obo:NCBITaxon_413075 a rdfs:Class ; rdfs:label "Infectious bronchitis virus RUS/L-1777/2005" ; rdfs:subClassOf obo:NCBITaxon_11120 . obo:NCBITaxon_231518 a rdfs:Class ; rdfs:label "SARS coronavirus GZ60" ; rdfs:subClassOf obo:NCBITaxon_694009 . obo:NCBITaxon_1897068 a rdfs:Class ; rdfs:label "Bat coronavirus Art.lit/2064/BRA/2011" ; rdfs:subClassOf obo:NCBITaxon_696098 . obo:CHEBI_32450 a rdfs:Class ; rdfs:label "D-cysteinate(2-)" ; rdfs:comment "The D-enantiomer of cysteinate(2-)." ; rdfs:subClassOf obo:CHEBI_32457 . obo:NCBITaxon_1788493 a rdfs:Class ; rdfs:label "Rhinolophus bat coronavirus BtCoV/4030-2" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:PR_Q8NEV4 a rdfs:Class ; rdfs:label "myosin-IIIa (human)" ; rdfs:comment "A myosin-IIIa that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000010863 , obo:PR_000029067 . obo:CHEBI_35341 a rdfs:Class ; rdfs:label "steroid" ; rdfs:comment "Any of naturally occurring compounds and synthetic analogues, based on the cyclopenta[a]phenanthrene carbon skeleton, partially or completely hydrogenated; there are usually methyl groups at C-10 and C-13, and often an alkyl group at C-17. By extension, one or more bond scissions, ring expansions and/or ring contractions of the skeleton may have occurred. Natural steroids are derived biogenetically from squalene which is a triterpene." ; rdfs:subClassOf obo:CHEBI_18059 , obo:CHEBI_51958 . obo:NCBITaxon_1476949 a rdfs:Class ; rdfs:label "Bat coronavirus IFB2012-13F" ; rdfs:subClassOf obo:NCBITaxon_696098 . obo:NCBITaxon_1964807 a rdfs:Class ; rdfs:label "Coronavirus JC02" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:CIDO_0000753 a rdfs:Class ; rdfs:label "SARS-CoV2 M protein binding to human BZW2" ; rdfs:comment "SARS-CoV2 M protein binding to human BZW2, as evidented by an affinity-purification mass spectrometry experiment" ; rdfs:subClassOf obo:CIDO_0000055 . obo:CIDO_0001075 a rdfs:Class ; rdfs:label "AA variant in SARS-CoV-2 nsp4 protein"@en ; rdfs:subClassOf obo:CIDO_0000714 . obo:CHEBI_47788 a rdfs:Class ; rdfs:label "3-oxo steroid" ; rdfs:comment "Any oxo steroid where an oxo substituent is located at position 3." ; rdfs:subClassOf obo:CHEBI_35789 , obo:CHEBI_3992 . obo:NCBITaxon_1788427 a rdfs:Class ; rdfs:label "Bat coronavirus MsBtCoV/4056" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:PR_000006082 a rdfs:Class ; rdfs:label "NADH-cytochrome b5 reductase 3" ; rdfs:comment "A protein that is a translation product of the human CYB5R3 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:NCBITaxon_1643901 a rdfs:Class ; rdfs:label "Bat coronavirus BEM077F" ; rdfs:subClassOf obo:NCBITaxon_696098 . obo:MPATH_603 a rdfs:Class ; rdfs:label "pathological anatomical entity" ; rdfs:comment "Anatomically located instance of pathological response or entity." ; rdfs:subClassOf obo:BFO_0000040 . obo:PR_000008770 a rdfs:Class ; rdfs:label "11-beta-hydroxysteroid dehydrogenase 1" ; rdfs:comment "A protein that is a translation product of the human HSD11B1 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:HP_0004308 a rdfs:Class ; rdfs:label "Ventricular arrhythmia" ; rdfs:subClassOf obo:HP_0011675 . obo:CIDO_0000403 a rdfs:Class ; rdfs:label "SARS-CoV-2 P.1.1 virus"@en ; rdfs:subClassOf obo:CIDO_0000406 . obo:HP_0000818 a rdfs:Class ; rdfs:label "Abnormality of the endocrine system" ; rdfs:comment "An abnormality of the endocrine system." ; rdfs:subClassOf obo:HP_0000118 . obo:CHEBI_50689 a rdfs:Class ; rdfs:label "reproductive control drug" ; rdfs:comment "A substance used either in the prevention or facilitation of pregnancy." ; rdfs:subClassOf obo:CHEBI_23888 . obo:NCBITaxon_186995 a rdfs:Class ; rdfs:label "Rhinolophinae" ; rdfs:subClassOf obo:NCBITaxon_58055 . a rdfs:Class ; rdfs:label "Malaria [Disease/Finding]" ; rdfs:subClassOf . obo:VO_0005195 a rdfs:Class ; rdfs:label "V590"@en ; rdfs:comment "A SARS-CoV-2 vaccine that uses a recombinant vesicular stomatitis virus (rVSV) platform, and is made by Merck. Development of the vaccine was discontinued on January 25, 2021." ; rdfs:subClassOf obo:VO_0005199 . obo:CIDO_0001057 a rdfs:Class ; rdfs:label "SARS-CoV2 orf9c protein binding to human NDUFB9" ; rdfs:comment "SARS-CoV2 orf9c protein binding to human NDUFB9, as evidented by an affinity-purification mass spectrometry experiment" ; rdfs:subClassOf obo:CIDO_0000054 . a rdfs:Class ; rdfs:label "Cell Transformation, Neoplastic [Disease/Finding]" ; rdfs:subClassOf . obo:NCBITaxon_1788413 a rdfs:Class ; rdfs:label "Bat coronavirus HpBtCoV/3740-1" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:NCBITaxon_424366 a rdfs:Class ; rdfs:label "Bat coronavirus HKU5-5" ; rdfs:subClassOf obo:NCBITaxon_694008 . obo:BFO_0000035 a rdfs:Class ; rdfs:label "process boundary"@en ; rdfs:comment "p is a process boundary =Def. p is a temporal part of a process & p has no proper temporal parts. (axiom label in BFO2 Reference: [084-001])"@en ; rdfs:subClassOf obo:BFO_0000003 . obo:GO_0045069 a rdfs:Class ; rdfs:label "regulation of viral genome replication" ; rdfs:comment "Any process that modulates the frequency, rate or extent of viral genome replication." ; rdfs:subClassOf obo:GO_1903900 . obo:PR_P04150 a rdfs:Class ; rdfs:label "glucocorticoid receptor (human)" ; rdfs:comment "A glucocorticoid receptor that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000011406 , obo:PR_000029067 . obo:VO_0005155 a rdfs:Class ; rdfs:label "NVX-CoV2373" ; rdfs:comment "A SARS-CoV 2 (rSARS-CoV-2) subunit vaccine made of nanoparticles composed of a trimeric full-length SARS-CoV-2 spike glycoprotein and Matrix-M1 adjuvant." ; rdfs:subClassOf obo:VO_0005269 . obo:HP_0011446 a rdfs:Class ; rdfs:label "Abnormality of higher mental function" ; rdfs:comment "Cognitive, psychiatric or memory anomaly." ; rdfs:subClassOf obo:HP_0012638 . obo:CHEBI_87114 a rdfs:Class ; rdfs:label "antibiotic fungicide" ; rdfs:comment "Any antibiotic antifungal agent that has been used as a fungicide." ; rdfs:subClassOf obo:CHEBI_86478 . obo:CHEBI_74783 a rdfs:Class ; rdfs:label "astringent" ; rdfs:comment "A compound that causes the contraction of body tissues, typically used to reduce bleeding from minor abrasions." ; rdfs:subClassOf obo:CHEBI_23888 . a rdfs:Class ; rdfs:label "Cyclosporine [Chemical/Ingredient]" ; rdfs:subClassOf . a rdfs:Class ; rdfs:label "Phlebitis [Disease/Finding]" ; rdfs:subClassOf , . obo:CHEBI_49886 a rdfs:Class ; rdfs:label "rimantadine" ; rdfs:subClassOf obo:CHEBI_13759 . obo:OPMI_0000499 a rdfs:Class ; rdfs:label "case management visit"@en ; rdfs:comment "An interaction with the healthcare system, without a care site, within a day, with no providers involved, for administrative purposes" ; rdfs:subClassOf obo:OPMI_0000482 . obo:NCBITaxon_1344565 a rdfs:Class ; rdfs:label "shorebird coronavirus" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:CHEBI_83976 a rdfs:Class ; rdfs:label "2-methyl fatty acid anion" ; rdfs:comment "A methyl-branched fatty acid anion obtained by deprotonation of the carboxy group of any 2-methyl fatty acid; major species at pH 7.3." ; rdfs:subClassOf obo:CHEBI_67013 . a rdfs:Class ; rdfs:label "Metabolic Diseases [Disease/Finding]" ; rdfs:subClassOf . a rdfs:Class ; rdfs:label "Anilides [Chemical/Ingredient]" ; rdfs:subClassOf . obo:PR_000001782 a rdfs:Class ; rdfs:label "interleukin-1 receptor-associated kinase 1" ; rdfs:comment "An interleukin-1 receptor-associated kinase IRAK1/3 that is a translation product of the human IRAK1 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000001781 . obo:CHEBI_26873 a rdfs:Class ; rdfs:label "terpenoid" ; rdfs:comment "Any isoprenoid that is a natural product or related compound formally derived from isoprene units. Terpenoids may contain oxygen in various functional groups. This class is subdivided according to the number of carbon atoms in the parent terpene. The skeleton of terpenoids may differ from strict additivity of isoprene units by the loss or shift of a fragment, generally a methyl group." ; rdfs:subClassOf obo:CHEBI_24913 . obo:CIDO_0020108 a rdfs:Class ; rdfs:label "Cue COVID-19 Test for Home and Over The Counter (OTC) Use" ; rdfs:seeAlso ; rdfs:subClassOf obo:CIDO_0000454 . obo:CHEBI_33282 a rdfs:Class ; rdfs:label "antibacterial agent" ; rdfs:comment "A substance (or active part thereof) that kills or slows the growth of bacteria." ; rdfs:subClassOf obo:CHEBI_33281 . obo:NCBITaxon_1429853 a rdfs:Class ; rdfs:label "Alphacoronavirus Pipistrellus kuhlii/Italy/206679-3/2010" ; rdfs:subClassOf obo:NCBITaxon_366617 . obo:IDO_0000594 a rdfs:Class ; rdfs:label "direct host exposure to infectious agent"@en ; rdfs:comment "A process in which a potential host of an infectious agent comes into direct physical contact with the infectious agent."@en ; rdfs:subClassOf obo:IDO_0000658 . obo:CHEBI_39417 a rdfs:Class ; rdfs:label "branched-chain saturated fatty acid" ; rdfs:comment "Any saturated fatty acid with a carbon side-chain or isopropyl termination." ; rdfs:subClassOf obo:CHEBI_26607 , obo:CHEBI_35819 . obo:NCBITaxon_430472 a rdfs:Class ; rdfs:label "Murine coronavirus SA59/RJHM" ; rdfs:subClassOf obo:NCBITaxon_11138 . obo:CHEBI_76042 a rdfs:Class ; rdfs:label "aromatic amino-acid zwitterion" ; rdfs:comment "An amino acid zwitterion obtained by transfer of a proton from the carboxy to the amino group of any aromatic amino-acid." ; rdfs:subClassOf obo:CHEBI_35238 . obo:CIDO_0000083 a rdfs:Class ; rdfs:label "chemical role modulating host immune response to MERS-CoV infection"@en ; rdfs:comment "A role of a chemical effective in modulating host response to MERS-CoV infection" ; rdfs:subClassOf obo:CIDO_0000080 . obo:CHEBI_38092 a rdfs:Class ; rdfs:label "cardenolide glycoside" ; rdfs:comment "Any member of the class of cardenolides with glycosyl residues attached to position 3." ; rdfs:subClassOf obo:CHEBI_74634 , obo:CHEBI_83970 . obo:VO_0005092 a rdfs:Class ; rdfs:label "Nanocovax"@en ; rdfs:comment "A SARS-CoV-2 subunit vaccine with recombinant SARS-CoV-2 spike (S) protein and aluminum phosphate adjuvant" ; rdfs:subClassOf obo:VO_0005202 . obo:NCBITaxon_1805463 a rdfs:Class ; rdfs:label "Bat betacoronavirus" ; rdfs:subClassOf obo:NCBITaxon_696098 . obo:NCBITaxon_1429860 a rdfs:Class ; rdfs:label "Betacoronavirus Pipistrellus kuhlii/Italy/206645-54/2011" ; rdfs:subClassOf obo:NCBITaxon_696098 . obo:CHEBI_36244 a rdfs:Class ; rdfs:label "dicarboxylic acid monoester" ; rdfs:comment "A monoester of a dicarboxylic acid." ; rdfs:subClassOf obo:CHEBI_131927 , obo:CHEBI_33308 , obo:CHEBI_33575 . obo:PR_000012734 a rdfs:Class ; rdfs:label "serine/threonine-protein kinase Pim-3" ; rdfs:comment "A protein that is a translation product of the human PIM3 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:CIDO_0000353 a rdfs:Class ; rdfs:label "COVID-19 lateral flow immunoassay"@en ; rdfs:comment "a COVID-19 ELISA serological diagnostic assay is a kind of rapid test that run the liquid sample along the surface of a pad with reactive molecules that show a visual positive or negative results. This testing dose not need for specialized and costly equipment."@en ; rdfs:subClassOf obo:CIDO_0000263 . obo:CIDO_0020017 a rdfs:Class ; rdfs:label "Alinity m Resp-4-Plex" ; rdfs:seeAlso ; rdfs:subClassOf obo:CIDO_0000454 . obo:PR_000002997 a rdfs:Class ; rdfs:label "proto-oncogene SRC-like tyrosine-protein kinase" ; rdfs:comment "A protein that contains one copy of the SH3 domain (Pfam:PF00018), a copy of the SH2 domain (Pfam:PF00017), and a copy of the Protein tyrosine kinase (Pfam:PF07714) domain. Members of this class are cytoplasmic protein-tyrosine kinases believed to be involved in signal transduction." ; rdfs:subClassOf obo:PR_000000001 . obo:CIDO_0000476 a rdfs:Class ; rdfs:label "CAQYYNGIMVLPGVA" ; rdfs:comment "A coronavirus epitope that is part of some S protein from HCoV 229E composed of the following amino acids CAQYYNGIMVLPGVA" ; rdfs:subClassOf obo:CIDO_0000451 . obo:NCBITaxon_2042594 a rdfs:Class ; rdfs:label "Coronavirus PREDICT CoV-71" ; rdfs:subClassOf obo:NCBITaxon_696098 . obo:CIDO_0001060 a rdfs:Class ; rdfs:label "SARS-CoV2 orf9c protein binding to human PIGS" ; rdfs:comment "SARS-CoV2 orf9c protein binding to human PIGS, as evidented by an affinity-purification mass spectrometry experiment" ; rdfs:subClassOf obo:CIDO_0000054 . obo:PR_Q8IV08 a rdfs:Class ; rdfs:label "5'-3' exonuclease PLD3 (human)" ; rdfs:comment "A 5'-3' exonuclease PLD3 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000012845 , obo:PR_000029067 . obo:CHEBI_32784 a rdfs:Class ; rdfs:label "tyrosinate(1-)" ; rdfs:comment "An alpha-amino-acid anion that is the conjugate base of tyrosine, arising from deprotonation of the carboxy group." ; rdfs:subClassOf obo:CHEBI_33558 . obo:GO_0043200 a rdfs:Class ; rdfs:label "response to amino acid" ; rdfs:comment "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an amino acid stimulus. An amino acid is a carboxylic acids containing one or more amino groups." ; rdfs:subClassOf obo:GO_0010243 , obo:GO_0042221 , obo:GO_1901700 . obo:CIDO_0020070 a rdfs:Class ; rdfs:label "CDC 2019-Novel Coronavirus (2019-nCoV) Real-Time RT-PCR Diagnostic Panel (CDC)" ; rdfs:seeAlso ; rdfs:subClassOf obo:CIDO_0000454 . obo:NCBITaxon_349344 a rdfs:Class ; rdfs:label "Bat SARS CoV Rp3/2004" ; rdfs:subClassOf obo:NCBITaxon_694009 . a rdfs:Class ; rdfs:label "Peripheral Vascular Diseases [Disease/Finding]" ; rdfs:subClassOf . obo:NCBITaxon_32523 a rdfs:Class ; rdfs:label "Tetrapoda" ; rdfs:subClassOf obo:NCBITaxon_117571 , obo:NCBITaxon_1338369 . obo:HP_0000458 a rdfs:Class ; rdfs:label "Anosmia" ; rdfs:comment "An inability to perceive odors. This is a general term describing inability to smell arising in any part of the process of smelling from absorption of odorants into the nasal mucous overlying the olfactory epithelium, diffusion to the cilia, binding to olfactory receptor sites, generation of action potentials in olfactory neurons, and perception of a smell." ; rdfs:subClassOf obo:HP_0004408 . obo:NCBITaxon_1076417 a rdfs:Class ; rdfs:label "Alphacoronavirus N.las/C/Spain/2007" ; rdfs:subClassOf obo:NCBITaxon_366617 . obo:NCBITaxon_1881088 a rdfs:Class ; rdfs:label "Miniopterus fuliginosus coronavirus" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:CIDO_0000940 a rdfs:Class ; rdfs:label "SARS-CoV2 nsp8 protein binding to human NGDN" ; rdfs:comment "SARS-CoV2 nsp8 protein binding to human NGDN, as evidented by an affinity-purification mass spectrometry experiment" ; rdfs:subClassOf obo:CIDO_0000582 . obo:HP_0004309 a rdfs:Class ; rdfs:label "Ventricular preexcitation" ; rdfs:comment "An abnormality in which the cardiac ventricles depolarize too early as a result of an abnormality of cardiac conduction pathways such as an accessory pathway." ; rdfs:subClassOf obo:HP_0004308 . obo:NCBITaxon_422214 a rdfs:Class ; rdfs:label "Bovine coronavirus R-AH65" ; rdfs:subClassOf obo:NCBITaxon_11128 . obo:NCBITaxon_1788458 a rdfs:Class ; rdfs:label "Hipposideros bat coronavirus BtCoV/3740-1" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:DRON_00018854 a rdfs:Class ; rdfs:label "anidulafungin" ; rdfs:subClassOf obo:OBI_0000047 . obo:GO_1901700 a rdfs:Class ; rdfs:label "response to oxygen-containing compound" ; rdfs:comment "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an oxygen-containing compound stimulus." ; rdfs:subClassOf obo:GO_0042221 . obo:GO_0034655 a rdfs:Class ; rdfs:label "nucleobase-containing compound catabolic process" ; rdfs:comment "The chemical reactions and pathways resulting in the breakdown of nucleobases, nucleosides, nucleotides and nucleic acids." ; rdfs:subClassOf obo:GO_0006139 , obo:GO_0019439 , obo:GO_0044270 , obo:GO_0046700 , obo:GO_1901361 . obo:NCBITaxon_228415 a rdfs:Class ; rdfs:label "SARS coronavirus CUHK-W1" ; rdfs:subClassOf obo:NCBITaxon_694009 . obo:GO_0042325 a rdfs:Class ; rdfs:label "regulation of phosphorylation" ; rdfs:comment "Any process that modulates the frequency, rate or extent of addition of phosphate groups into a molecule." ; rdfs:subClassOf obo:GO_0019220 . obo:NCBITaxon_384343 a rdfs:Class ; rdfs:label "Human coronavirus NO/0053/04" ; rdfs:subClassOf obo:NCBITaxon_384335 . obo:HP_0004372 a rdfs:Class ; rdfs:label "Reduced consciousness/confusion" ; rdfs:subClassOf obo:HP_0011446 . obo:CIDO_0001137 a rdfs:Class ; rdfs:label "SARS-CoV2 orf8 protein binding to human UGGT2"@en ; rdfs:comment "SARS-CoV2 orf8 protein binding to human UGGT2, as evidented by an affinity-purification mass spectrometry experiment" ; rdfs:subClassOf obo:CIDO_0000051 . obo:CIDO_0020255 a rdfs:Class ; rdfs:label "Quest SARS-CoV-2 rRT-PCR" ; rdfs:seeAlso ; rdfs:subClassOf obo:CIDO_0000454 . obo:NCBITaxon_422141 a rdfs:Class ; rdfs:label "Giraffe coronavirus US/OH3-TC/2006" ; rdfs:subClassOf obo:NCBITaxon_11128 . obo:HP_0001945 a rdfs:Class ; rdfs:label "Fever" ; rdfs:comment "Elevated body temperature due to failed thermoregulation." ; rdfs:subClassOf obo:HP_0012337 . obo:NCBITaxon_1679890 a rdfs:Class ; rdfs:label "Coronavirus RCoV/D_RMU10_1940/Myo_gla/GER/2010" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:CIDO_0000928 a rdfs:Class ; rdfs:label "SARS-CoV2 nsp8 protein binding to human EXOSC3" ; rdfs:comment "SARS-CoV2 nsp8 protein binding to human EXOSC3, as evidented by an affinity-purification mass spectrometry experiment" ; rdfs:subClassOf obo:CIDO_0000582 . obo:CHEBI_38958 a rdfs:Class ; rdfs:label "indole alkaloid" ; rdfs:comment "An alkaloid containing an indole skeleton." ; rdfs:subClassOf obo:CHEBI_22315 , obo:CHEBI_24828 . obo:PR_000017414 a rdfs:Class ; rdfs:label "wolframin" ; rdfs:comment "A protein that is a translation product of the human WFS1 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . a rdfs:Class ; rdfs:label "Decreased Glucocorticoid Secretion [PE]" ; rdfs:subClassOf . obo:PR_Q9NQT5 a rdfs:Class ; rdfs:label "exosome complex component RRP40 (human)" ; rdfs:comment "An exosome complex component RRP40 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000007260 , obo:PR_000029067 . obo:PR_P29322 a rdfs:Class ; rdfs:label "ephrin type-A receptor 8 (human)" ; rdfs:comment "An ephrin type-A receptor 8 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000007128 , obo:PR_000029067 . obo:GO_0050906 a rdfs:Class ; rdfs:label "detection of stimulus involved in sensory perception" ; rdfs:comment "The series of events involved in sensory perception in which a sensory stimulus is received and converted into a molecular signal." ; rdfs:subClassOf obo:GO_0051606 . obo:PR_Q9Y616 a rdfs:Class ; rdfs:label "interleukin-1 receptor-associated kinase 3 (human)" ; rdfs:comment "An interleukin-1 receptor-associated kinase 3 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000001784 , obo:PR_000029067 . obo:CIDO_0000421 a rdfs:Class ; rdfs:label "human MERS patient"@en ; rdfs:comment "a human patient who is infected with MERS coronavirus" ; rdfs:subClassOf obo:CIDO_0000419 . obo:GO_0008104 a rdfs:Class ; rdfs:label "protein localization" ; rdfs:comment "Any process in which a protein is transported to, or maintained in, a specific location." ; rdfs:subClassOf obo:GO_0033036 . obo:PR_000017403 a rdfs:Class ; rdfs:label "Wee1-like protein kinase" ; rdfs:comment "A protein that is a translation product of the human WEE1 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . a rdfs:Class ; rdfs:label "Salmonella Infections [Disease/Finding]" ; rdfs:subClassOf . obo:OAE_0000308 a rdfs:Class ; rdfs:label "dysgeusia AE" ; rdfs:comment "a behavior and neurological AE that has an outcome of distortion of the sense of taste" ; rdfs:subClassOf obo:OAE_0000580 . obo:NCBITaxon_2509494 a rdfs:Class ; rdfs:label "Merbecovirus" ; rdfs:subClassOf obo:NCBITaxon_694002 . obo:NCBITaxon_201800 a rdfs:Class ; rdfs:label "Pantherophis" ; rdfs:subClassOf obo:NCBITaxon_169863 . obo:CHEBI_15428 a rdfs:Class ; rdfs:label "glycine" ; rdfs:comment "The simplest (and the only achiral) proteinogenic amino acid, with a hydrogen atom as its side chain." ; rdfs:subClassOf obo:CHEBI_26650 , obo:CHEBI_33704 , obo:CHEBI_83813 . obo:GO_0045047 a rdfs:Class ; rdfs:label "protein targeting to ER" ; rdfs:comment "The process of directing proteins towards the endoplasmic reticulum (ER) using signals contained within the protein. One common mechanism uses a 16- to 30-residue signal sequence, typically located at the N-terminus of the protein and containing positively charged amino acids followed by a continuous stretch of hydrophobic residues, which directs the ribosome to the ER membrane and initiates transport of the growing polypeptide across the ER membrane." ; rdfs:subClassOf obo:GO_0006605 , obo:GO_0072599 . obo:CHEBI_47495 a rdfs:Class ; rdfs:label "N-[2-(4-bromocinnamylamino)ethyl]isoquinoline-5-sulfonamide" ; rdfs:comment "A member of the class of isoquinolines that is the sulfonamide obtained by formal condensation of the sulfo group of isoquinoline-5-sulfonic acid with the primary amino group of N(1)-[3-(4-bromophenyl)prop-2-en-1-yl]ethane-1,2-diamine." ; rdfs:subClassOf obo:CHEBI_24922 , obo:CHEBI_35358 , obo:CHEBI_37149 , obo:CHEBI_50995 , obo:CHEBI_78840 . obo:NCBITaxon_2042583 a rdfs:Class ; rdfs:label "Coronavirus PREDICT CoV-59" ; rdfs:subClassOf obo:NCBITaxon_366617 . obo:CHEBI_32773 a rdfs:Class ; rdfs:label "D-tyrosinate(1-)" ; rdfs:comment "An optically active form of tyrosinate(1-) having D-configuration." ; rdfs:subClassOf obo:CHEBI_32784 . obo:CHEBI_50902 a rdfs:Class ; rdfs:label "genotoxin" ; rdfs:comment "A role played by a chemical compound to induce direct or indirect DNA damage. Such damage can potentially lead to the formation of a malignant tumour, but DNA damage does not lead inevitably to the creation of cancerous cells." ; rdfs:subClassOf obo:CHEBI_52209 . a rdfs:Class ; rdfs:label "Coumarins [Chemical/Ingredient]" ; rdfs:subClassOf . obo:CHEBI_88230 a rdfs:Class ; rdfs:label "autophagy inhibitor" ; rdfs:comment "Any compound that inhibits the process of autophagy (the self-digestion of one or more components of a cell through the action of enzymes originating within the same cell)." ; rdfs:subClassOf obo:CHEBI_35222 , obo:CHEBI_52206 . obo:CHEBI_33485 a rdfs:Class ; rdfs:label "chalcogen oxoanion" ; rdfs:subClassOf obo:CHEBI_33304 , obo:CHEBI_35406 . obo:CIDO_0000760 a rdfs:Class ; rdfs:label "SARS-CoV2 M protein binding to human PITRM1" ; rdfs:comment "SARS-CoV2 M protein binding to human PITRM1, as evidented by an affinity-purification mass spectrometry experiment" ; rdfs:subClassOf obo:CIDO_0000055 . obo:CIDO_0000036 a rdfs:Class ; rdfs:label "COVID-19 diagnostic process by immunofluorescence serological assay"@en ; rdfs:comment "A COVID-19 diagnostic process that uses an serological assay that tests the serum from the blood specimen by an Immunofluorescence assay (IFA)" ; rdfs:subClassOf obo:CIDO_0000018 . obo:CIDO_0000200 a rdfs:Class ; rdfs:label "host-MERS-CoV interaction"@en ; rdfs:subClassOf obo:CIDO_0000084 . obo:PR_Q15746 a rdfs:Class ; rdfs:label "myosin light chain kinase, smooth muscle (human)" ; rdfs:comment "A myosin light chain kinase, smooth muscle that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000010845 , obo:PR_000029067 . obo:CHEBI_25805 a rdfs:Class ; rdfs:label "oxygen atom" ; rdfs:subClassOf obo:CHEBI_25585 , obo:CHEBI_33303 . obo:CIDO_0020227 a rdfs:Class ; rdfs:label "OSUWMC COVID-19 RT-PCR test" ; rdfs:seeAlso ; rdfs:subClassOf obo:CIDO_0000454 . obo:NCBITaxon_1699095 a rdfs:Class ; rdfs:label "Camel alphacoronavirus" ; rdfs:subClassOf obo:NCBITaxon_11137 . obo:PR_000044631 a rdfs:Class ; rdfs:label "adrenoceptor protein" ; rdfs:comment "A rhodopsin-like G-protein coupled receptor that is a translation product of the human ADRA1A, ADRA1B, ADRA1D, ADRA2A, ADRA2B, ADRA2C, ADRB1, ADRB2, or ADRB3 genes, 1:1 orthologs thereof, or a semi-ortholog thereof." ; rdfs:subClassOf obo:PR_000001094 . obo:NCBITaxon_441984 a rdfs:Class ; rdfs:label "Yellow-bellied weasel coronavirus Guangxi/D726/2005" ; rdfs:subClassOf obo:NCBITaxon_441985 . obo:CHEBI_33710 a rdfs:Class ; rdfs:label "alpha-amino-acid residue" ; rdfs:subClassOf obo:CHEBI_33708 . obo:NCBITaxon_1269302 a rdfs:Class ; rdfs:label "Coronavirus BtCoV/KCR24/Ano_geo/CRC/2010" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:CHEBI_35821 a rdfs:Class ; rdfs:label "anticholesteremic drug" ; rdfs:comment "A substance used to lower plasma cholesterol levels." ; rdfs:subClassOf obo:CHEBI_35679 . obo:GO_0007213 a rdfs:Class ; rdfs:label "G protein-coupled acetylcholine receptor signaling pathway" ; rdfs:comment "A G protein-coupled receptor signaling pathway initiated by a ligand binding to an acetylcholine receptor on the surface of a target cell, and ends with regulation of a downstream cellular process, e.g. transcription." ; rdfs:subClassOf obo:GO_0007165 , obo:GO_0007186 . a rdfs:Class ; rdfs:label "Vision Disorders [Disease/Finding]" ; rdfs:subClassOf , . obo:NCBITaxon_903617 a rdfs:Class ; rdfs:label "Kenya bat coronavirus BtKY79" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:OAE_0004576 a rdfs:Class ; rdfs:label "Level 1 TTS AE"@en ; rdfs:comment "A definit case of TTS" ; rdfs:subClassOf obo:OAE_0004540 . obo:PR_000006959 a rdfs:Class ; rdfs:label "interferon-induced, double-stranded RNA-activated protein kinase" ; rdfs:comment "A protein that is a translation product of the human EIF2AK2 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:NCBITaxon_28293 a rdfs:Class ; rdfs:label "Enteric coronavirus" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:PR_Q14240 a rdfs:Class ; rdfs:label "eukaryotic initiation factor 4A-II (human)" ; rdfs:comment "A eukaryotic initiation factor 4A-II that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000006987 , obo:PR_000029067 . obo:CHEBI_23636 a rdfs:Class ; rdfs:label "deoxyribonucleoside" ; rdfs:subClassOf obo:CHEBI_33838 . obo:PR_000009979 a rdfs:Class ; rdfs:label "leukocyte tyrosine kinase receptor" ; rdfs:comment "A protein that is a translation product of the human LTK gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . a rdfs:Class ; rdfs:label "Pancreatic Neoplasms [Disease/Finding]" ; rdfs:subClassOf , , . obo:CHEBI_22718 a rdfs:Class ; rdfs:label "benzoates" ; rdfs:comment "A monocarboxylic acid anion obtained by deprotonation of the carboxy group of any benzoic acid." ; rdfs:subClassOf obo:CHEBI_35757 . obo:PR_P11362 a rdfs:Class ; rdfs:label "fibroblast growth factor receptor 1 (human)" ; rdfs:comment "A fibroblast growth factor receptor 1 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000001448 , obo:PR_000029067 . obo:OBI_0000834 a rdfs:Class ; rdfs:label "high molecular weight DNA extract" ; rdfs:comment "The output of an extraction process in which DNA molecules above a molecular weight cutoff are purified in order to exclude DNA from organellas." ; rdfs:subClassOf obo:OBI_0001051 . obo:CHEBI_27594 a rdfs:Class ; rdfs:label "carbon atom" ; rdfs:subClassOf obo:CHEBI_25585 , obo:CHEBI_33306 . obo:NCBITaxon_258970 a rdfs:Class ; rdfs:label "SARS coronavirus TW7" ; rdfs:subClassOf obo:NCBITaxon_694009 . obo:PR_P22694 a rdfs:Class ; rdfs:label "cAMP-dependent protein kinase catalytic subunit beta (human)" ; rdfs:comment "A cAMP-dependent protein kinase catalytic subunit beta that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000013223 , obo:PR_000029067 . obo:PR_Q9H422 a rdfs:Class ; rdfs:label "homeodomain-interacting protein kinase 3 (human)" ; rdfs:comment "A homeodomain-interacting protein kinase 3 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000008568 , obo:PR_000029067 . obo:CIDO_0000917 a rdfs:Class ; rdfs:label "SARS-CoV2 nsp7 protein binding to human RALA" ; rdfs:comment "SARS-CoV2 nsp7 protein binding to human RALA, as evidented by an affinity-purification mass spectrometry experiment" ; rdfs:subClassOf obo:CIDO_0000049 . obo:CHEBI_3992 a rdfs:Class ; rdfs:label "cyclic ketone" ; rdfs:subClassOf obo:CHEBI_17087 . obo:CHEBI_36021 a rdfs:Class ; rdfs:label "octadec-9-enoic acid" ; rdfs:comment "An octadecenoic acid with a double bond at C-9." ; rdfs:subClassOf obo:CHEBI_25634 . obo:GO_0140105 a rdfs:Class ; rdfs:label "interleukin-10-mediated signaling pathway" ; rdfs:comment "The series of molecular signals initiated by interleukin-10 binding to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription." ; rdfs:subClassOf obo:GO_0007166 . obo:CIDO_0000359 a rdf:Property ; rdfs:label "pathway susceptibly up-regulated in"@en ; rdfs:range ; rdfs:subPropertyOf obo:CIDO_0000358 . obo:OBI_1200000 a rdfs:Class ; rdfs:label "FFPE specimen" ; rdfs:comment "A specimen that has been fixed in formalin and embedded in paraffin." ; rdfs:subClassOf obo:OBI_0000950 . a rdfs:Class ; rdfs:label "LOPERAMIDE" ; rdfs:subClassOf . obo:CHEBI_55438 a rdfs:Class ; rdfs:label "Ile(5)-angiotensin II (1-7)" ; rdfs:comment "An angiotensin compound consisting of the linear heptapeptide sequence L-Asp-L-Arg-L-Val-L-Tyr-L-Ile-L-His-L-Pro." ; rdfs:subClassOf obo:CHEBI_48433 . obo:CIDO_0000252 a rdfs:Class ; rdfs:label "coronavirus survival in lysosome"@en ; rdfs:subClassOf obo:CIDO_0000251 . obo:NCBITaxon_264381 a rdfs:Class ; rdfs:label "SARS coronavirus TW-GD4" ; rdfs:subClassOf obo:NCBITaxon_264370 . obo:CHEBI_78113 a rdfs:Class ; rdfs:label "fatty acid anion 3:0" ; rdfs:comment "Any saturated fatty acid anion containing 3 carbons. Formed by deprotonation of the carboxylic acid moiety. Major species at pH 7.3." ; rdfs:subClassOf obo:CHEBI_58951 , obo:CHEBI_58953 . obo:CIDO_0000633 a rdfs:Class ; rdfs:label "A1708D in SARS-CoV-2 pp1a protein" ; rdfs:comment "An AA mutation or AA variant that has mutated an amino acid at position 1708 into a aspartic acid in pp1a." ; rdfs:subClassOf obo:CIDO_0001074 . obo:CIDO_0020104 a rdfs:Class ; rdfs:label "CRSP SARS-CoV-2 Real-time Reverse Transcriptase (RT)-PCR Diagnostic Assay" ; rdfs:seeAlso ; rdfs:subClassOf obo:CIDO_0000454 . obo:NCBITaxon_123595 a rdfs:Class ; rdfs:label "Murine hepatitis virus strain ML-11" ; rdfs:subClassOf obo:NCBITaxon_11138 . obo:APOLLO_SV_00000413 a rdfs:Class ; rdfs:label "transmission rate of pathogen to human from Wolbachia-infected mosquito bites"@en ; rdfs:comment "The rate at which bites of mosquitoes infected with both Wolbachia and a particular pathogen such as dengue result in an infection in a susceptible human host."@en ; rdfs:subClassOf obo:OBI_0001554 . obo:CHEBI_35842 a rdfs:Class ; rdfs:label "antirheumatic drug" ; rdfs:comment "A drug used to treat rheumatoid arthritis." ; rdfs:subClassOf obo:CHEBI_23888 . obo:CHEBI_49976 a rdfs:Class ; rdfs:label "zinc dichloride" ; rdfs:comment "A compound of zinc and chloride ions in the ratio 1:2. It exists in four crystalline forms, in each of which the Zn(2+) ions are trigonal planar coordinated to four chloride ions." ; rdfs:subClassOf obo:CHEBI_27364 , obo:CHEBI_36093 . obo:OAE_0001201 a rdfs:Class ; rdfs:label "myocarditis AE" ; rdfs:comment "an inflammation AE that has an outcome of inflammation of the heart muscle" ; rdfs:subClassOf obo:OAE_0000557 . obo:OAE_0003693 a rdfs:Class ; rdfs:label "Grade 4 myocarditis AE" ; rdfs:comment "a myocarditis AE that has life-threatening consequences; urgent intervention indicated (e.g., continuous IV therapy or mechanical hemodynamic support)" ; rdfs:subClassOf obo:OAE_0001201 . obo:PR_P62820 a rdfs:Class ; rdfs:label "Ras-related protein Rab-1A (human)" ; rdfs:comment "A Ras-related protein Rab-1A that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000013591 , obo:PR_000029067 . obo:NCBITaxon_2042569 a rdfs:Class ; rdfs:label "Coronavirus PREDICT CoV-43" ; rdfs:subClassOf obo:NCBITaxon_696098 . obo:OAE_0000834 a rdfs:Class ; rdfs:label "condition aggravated AE" ; rdfs:comment "an adverse event that has an outcome of condition that worsens" ; rdfs:subClassOf obo:OAE_0000063 . obo:HP_0033041 a rdfs:Class ; rdfs:label "Cytokine storm" ; rdfs:comment "Excessive or uncontrolled release of proinflammatory cytokines." ; rdfs:subClassOf obo:HP_0010978 . obo:CIDO_0000221 a rdf:Property ; rdfs:label "phenotype has causal agent"@en ; rdfs:range obo:BFO_0000040 ; rdfs:subPropertyOf obo:CIDO_0000220 . a rdfs:Class ; rdfs:label "eltrombopag [Chemical/Ingredient]" ; rdfs:subClassOf , , . obo:NCBITaxon_413074 a rdfs:Class ; rdfs:label "Infectious bronchitis virus AZE/L-1582/2004" ; rdfs:subClassOf obo:NCBITaxon_11120 . obo:NCBITaxon_235412 a rdfs:Class ; rdfs:label "SARS coronavirus Sin2679" ; rdfs:subClassOf obo:NCBITaxon_694009 . obo:CHEBI_76726 a rdfs:Class ; rdfs:label "EC 1.1.* (oxidoreductase acting on donor CH-OH group) inhibitor" ; rdfs:comment "An oxidoreductase inhibitor which interferes with the action of an oxidoreductase acting on the CH-OH group of donors (EC 1.1.*.*)." ; rdfs:subClassOf obo:CHEBI_76725 . obo:PR_Q9Y463 a rdfs:Class ; rdfs:label "dual specificity tyrosine-phosphorylation-regulated kinase 1B (human)" ; rdfs:comment "A dual specificity tyrosine-phosphorylation-regulated kinase 1B that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000006782 , obo:PR_000029067 . obo:NCBITaxon_1235996 a rdfs:Class ; rdfs:label "Human betacoronavirus 2c EMC/2012" ; rdfs:subClassOf obo:NCBITaxon_1335626 . obo:PR_Q9NRP7 a rdfs:Class ; rdfs:label "serine/threonine-protein kinase 36 (human)" ; rdfs:comment "A serine/threonine-protein kinase 36 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000015753 , obo:PR_000029067 . obo:CIDO_0000263 a rdfs:Class ; rdfs:label "COVID-19 ELISA serological diagnostic assay"@en ; rdfs:comment "A COVID-19 diagnostic process that uses an serological assay that tests the serum from the blood specimen by an Enzyme Linked Immunosorbent Assay (ELISA) screening test" ; rdfs:subClassOf obo:CIDO_0000262 . obo:CHEBI_15738 a rdfs:Class ; rdfs:label "staurosporine" ; rdfs:subClassOf obo:CHEBI_37697 , obo:CHEBI_38165 . obo:DOID_8725 a rdfs:Class ; rdfs:label "vascular dementia" ; rdfs:comment "A dementia that involves impairments in cognitive function caused by problems in blood vessels that feed the brain." ; rdfs:subClassOf obo:DOID_1307 . obo:CIDO_0000588 a rdfs:Class ; rdfs:label "SARS-CoV-2 binding to mouse cell"@en ; rdfs:comment "A host-coronovirus interaction that involves in the SARS-CoV-2 virus binding to a mouse cell" ; rdfs:subClassOf obo:CIDO_0000135 . obo:CIDO_0000292 a rdfs:Class ; rdfs:label "human infected by SARS-CoV-2"@en ; rdfs:subClassOf obo:CIDO_0000290 . obo:CHEBI_83039 a rdfs:Class ; rdfs:label "crustacean metabolite" ; rdfs:comment "An animal metabolite produced by arthropods such as crabs, lobsters, crayfish, shrimps and krill." ; rdfs:subClassOf obo:CHEBI_75767 . obo:CIDO_0000688 a rdfs:Class ; rdfs:label "Q498R in SARS-CoV-2 S protein" ; rdfs:comment "An AA mutation or AA variant that has mutated an amino acid at position 498 into a arginine in S protein." ; rdfs:subClassOf obo:CIDO_0000593 . obo:NCBITaxon_1644147 a rdfs:Class ; rdfs:label "Bat coronavirus BEM070F" ; rdfs:subClassOf obo:NCBITaxon_696098 . obo:CHEBI_17120 a rdfs:Class ; rdfs:label "hexanoate" ; rdfs:comment "A short-chain fatty acid anion that is the conjugate base of hexanoic acid (also known as caproic acid)." ; rdfs:subClassOf obo:CHEBI_58951 , obo:CHEBI_58954 , obo:CHEBI_78116 . obo:NCBITaxon_864590 a rdfs:Class ; rdfs:label "Bat coronavirus BB98-16/BGR/2008" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:PR_000013080 a rdfs:Class ; rdfs:label "peptidyl-prolyl cis-trans isomerase F, mitochondrial" ; rdfs:comment "A protein that is a translation product of the human PPIF gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:GO_1901576 a rdfs:Class ; rdfs:label "organic substance biosynthetic process" ; rdfs:comment "The chemical reactions and pathways resulting in the formation of an organic substance, any molecular entity containing carbon." ; rdfs:subClassOf obo:GO_0009058 , obo:GO_0071704 . obo:NCBITaxon_1788498 a rdfs:Class ; rdfs:label "Rhinolophus bat coronavirus BtCov/3990" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:PR_000025845 a rdfs:Class ; rdfs:label "ephrin receptor" ; rdfs:comment "A protein that consists of an Ephrin receptor ligand binding domain (Pfam:PF01404), two copies of the Fibronectin type III domain (Pfam:PF00041), and a copy of either type of SAM domain (Sterile alpha motif) (Pfam:PF00536 or Pfam:PF07647)." ; rdfs:subClassOf obo:PR_000000001 . obo:CIDO_0000508 a rdfs:Class ; rdfs:label "TGVNDAITQTSQALQ" ; rdfs:comment "A coronavirus epitope that is part of some S protein from HCoV 229E composed of the following amino acids TGVNDAITQTSQALQ" ; rdfs:subClassOf obo:CIDO_0000451 . obo:CHEBI_16385 a rdfs:Class ; rdfs:label "organic sulfide" ; rdfs:comment "Compounds having the structure RSR (R =/= H). Such compounds were once called thioethers." ; rdfs:subClassOf obo:CHEBI_26822 , obo:CHEBI_33261 . a rdfs:Class ; rdfs:label "Breast Diseases [Disease/Finding]" ; rdfs:subClassOf . obo:PR_000013061 a rdfs:Class ; rdfs:label "amidophosphoribosyltransferase" ; rdfs:comment "A protein that is a translation product of the human PPAT gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:DRON_00723537 a rdfs:Class ; rdfs:label "Glycyrrhizin, Ammoniated" ; rdfs:subClassOf obo:OBI_0000047 . obo:CIDO_0001007 a rdfs:Class ; rdfs:label "EIDD-2801" ; rdfs:subClassOf obo:CHEBI_23367 . obo:DRON_00059818 a rdfs:Class ; rdfs:label "benztropine mesylate 0.5 MG Oral Tablet" ; rdfs:subClassOf obo:DRON_00020931 . obo:NCBITaxon_2042643 a rdfs:Class ; rdfs:label "Kenya bat coronavirus/KY33/2006" ; rdfs:subClassOf obo:NCBITaxon_366617 . obo:NCBITaxon_1076296 a rdfs:Class ; rdfs:label "Ferret coronavirus 4E98" ; rdfs:subClassOf obo:NCBITaxon_366617 . obo:NCBITaxon_1159908 a rdfs:Class ; rdfs:label "Wigeon coronavirus HKU20" ; rdfs:subClassOf obo:NCBITaxon_2509469 . obo:PR_Q9HAU0 a rdfs:Class ; rdfs:label "pleckstrin homology domain-containing family A member 5 (human)" ; rdfs:comment "A pleckstrin homology domain-containing family A member 5 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000029067 , obo:PR_000030918 . obo:CIDO_0020088 a rdfs:Class ; rdfs:label "Compass Laboratory Services SARS-CoV2 Assay" ; rdfs:seeAlso ; rdfs:subClassOf obo:CIDO_0000454 . obo:CHEBI_16015 a rdfs:Class ; rdfs:label "L-glutamic acid" ; rdfs:comment "An optically active form of glutamic acid having L-configuration." ; rdfs:subClassOf obo:CHEBI_15705 , obo:CHEBI_18237 , obo:CHEBI_24318 , obo:CHEBI_83813 . obo:DOID_0111227 a rdfs:Class ; rdfs:label "chromosome 3-linked frontotemporal dementia" ; rdfs:comment "A frontotemporal dementia that has_material_basis_in heterozygous mutation in CHMP2B on 3p11.2." ; rdfs:subClassOf obo:DOID_9255 . obo:PR_000014208 a rdfs:Class ; rdfs:label "60S ribosomal protein L27" ; rdfs:comment "A protein that is a translation product of the human RPL27 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:NCBITaxon_1934037 a rdfs:Class ; rdfs:label "Calidris alba coronavirus" ; rdfs:subClassOf obo:NCBITaxon_749416 . obo:GO_0070887 a rdfs:Class ; rdfs:label "cellular response to chemical stimulus" ; rdfs:comment "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chemical stimulus." ; rdfs:subClassOf obo:GO_0042221 , obo:GO_0051716 . obo:PR_000007161 a rdfs:Class ; rdfs:label "ELKS/Rab6-interacting/CAST family member 1" ; rdfs:comment "A protein that is a translation product of the human ERC1 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:OPMI_0000566 a rdfs:Class ; rdfs:label "drug exposure start datetime"@en ; rdfs:comment "The date and time on which a drug exposure starts." ; rdfs:subClassOf obo:OPMI_0000564 . obo:NCBITaxon_903583 a rdfs:Class ; rdfs:label "Kenya bat coronavirus BtKY45" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:PR_P35498 a rdfs:Class ; rdfs:label "sodium channel protein type 1 subunit alpha (human)" ; rdfs:comment "A sodium channel protein type 1 subunit alpha that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000002095 , obo:PR_000029067 . obo:CHEBI_64709 a rdfs:Class ; rdfs:label "organic acid" ; rdfs:comment "Any organic molecular entity that is acidic and contains carbon in covalent linkage." ; rdfs:subClassOf obo:CHEBI_50860 . obo:NCBITaxon_2727861 a rdfs:Class ; rdfs:label "unclassified Tegacovirus" ; rdfs:subClassOf obo:NCBITaxon_2509514 . obo:GO_0072503 a rdfs:Class ; rdfs:label "cellular divalent inorganic cation homeostasis" ; rdfs:comment "Any process involved in the maintenance of an internal steady state of divalent cations at the level of a cell." ; rdfs:subClassOf obo:GO_0030003 , obo:GO_0072507 . obo:CHEBI_140592 a rdfs:Class ; rdfs:label "onalespib" ; rdfs:comment "A member of the class of isoindoles that is isoindole in which the amino group has been acylated by a 2,4-dihydroxy-5-isopropylbenzoyl group and in which position 5 of the isoidole moiety has been substituted by a (4-methylpiperazin-1-yl)methyl group. A second-generation Hsp90 inhibitor." ; rdfs:subClassOf obo:CHEBI_140326 , obo:CHEBI_22702 , obo:CHEBI_24897 , obo:CHEBI_33572 , obo:CHEBI_46845 . obo:CHEBI_7956 a rdfs:Class ; rdfs:label "penciclovir" ; rdfs:comment "A member of the class of 2-aminopurines that is guanine in which the hydrogen at position 9 is substituted by a 4-hydroxy-3-(hydroxymethyl)but-1-yl group. An antiviral drug, it is administered topically for treatment of herpes labialis. A prodrug, famciclovir, is used for oral administration." ; rdfs:subClassOf obo:CHEBI_20702 , obo:CHEBI_26287 . obo:OPMI_0000483 a rdfs:Class ; rdfs:label "visit occurrence identifier"@en ; rdfs:comment "A centrally registered identifier that refers to a specific visit occurrence. This identifier identifies a unique interaction between a person and the health care system." ; rdfs:subClassOf obo:IAO_0000578 . obo:PR_P08922 a rdfs:Class ; rdfs:label "proto-oncogene tyrosine-protein kinase ROS (human)" ; rdfs:comment "A proto-oncogene tyrosine-protein kinase ROS that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000014165 , obo:PR_000029067 . obo:CHEBI_136889 a rdfs:Class ; rdfs:label "5beta steroid" ; rdfs:comment "Any steroid that has beta-configuration at position 5." ; rdfs:subClassOf obo:CHEBI_35341 . obo:NCBITaxon_2078581 a rdfs:Class ; rdfs:label "Quail coronavirus UAE-HKU30" ; rdfs:subClassOf obo:NCBITaxon_2724161 . obo:NCBITaxon_1476950 a rdfs:Class ; rdfs:label "Bat coronavirus IFB2012-17F" ; rdfs:subClassOf obo:NCBITaxon_696098 . obo:CHEBI_23524 a rdfs:Class ; rdfs:label "cytidines" ; rdfs:subClassOf obo:CHEBI_39446 . obo:NCBITaxon_1699096 a rdfs:Class ; rdfs:label "Camel coronavirus HKU23" ; rdfs:subClassOf obo:NCBITaxon_2724078 . obo:NCBITaxon_422219 a rdfs:Class ; rdfs:label "Bovine coronavirus R-AH187" ; rdfs:subClassOf obo:NCBITaxon_11128 . obo:PR_000017023 a rdfs:Class ; rdfs:label "UBX domain-containing protein 8" ; rdfs:comment "A protein that is a translation product of the human UBXN8 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:GO_0045017 a rdfs:Class ; rdfs:label "glycerolipid biosynthetic process" ; rdfs:comment "The chemical reactions and pathways resulting in the formation of glycerolipids, any lipid with a glycerol backbone." ; rdfs:subClassOf obo:GO_0008610 , obo:GO_0044249 , obo:GO_0046486 . obo:NCBITaxon_1346310 a rdfs:Class ; rdfs:label "Betacoronavirus BtCoV/Rhi_hip/R7-08/SPA/2010" ; rdfs:subClassOf obo:NCBITaxon_696098 . obo:PR_000009022 a rdfs:Class ; rdfs:label "inosine-5'-monophosphate dehydrogenase 2" ; rdfs:comment "A protein that is a translation product of the human IMPDH2 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:PR_000006933 a rdfs:Class ; rdfs:label "epidermal growth factor receptor" ; rdfs:comment "An EGF receptor type tyrosine-protein kinase that is a translation product of the human EGFR gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000001812 . a rdfs:Class ; rdfs:label "DALBAVANCIN" ; rdfs:subClassOf . obo:CHEBI_24836 a rdfs:Class ; rdfs:label "inorganic oxide" ; rdfs:subClassOf obo:CHEBI_24835 , obo:CHEBI_25741 . obo:CIDO_0000480 a rdfs:Class ; rdfs:label "ELLQFVTDPTLIVAS" ; rdfs:comment "A coronavirus epitope that is part of some S protein from HCoV 229E composed of the following amino acids ELLQFVTDPTLIVAS" ; rdfs:subClassOf obo:CIDO_0000451 . obo:PR_P11142 a rdfs:Class ; rdfs:label "heat shock cognate 71 kDa protein (human)" ; rdfs:comment "A heat shock cognate 71 kDa protein that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000008812 , obo:PR_000029067 . obo:NCBITaxon_1429865 a rdfs:Class ; rdfs:label "Betacoronavirus Rhinolophus hipposideros/Italy/196814/2011" ; rdfs:subClassOf obo:NCBITaxon_696098 . obo:OPMI_0000549 a rdfs:Class ; rdfs:label "preliminary admission diagnosis status"@en ; rdfs:comment "The status of have the primary admission diagnosis" ; rdfs:subClassOf obo:OPMI_0000540 . obo:OBI_0000379 a rdfs:Class ; rdfs:label "mechanical function"@en ; rdfs:comment "A mechanical function is a function that is realised via mechanical work (through an certain amount of energy transferred by some force)."@en ; rdfs:subClassOf obo:BFO_0000034 . obo:CIDO_0001104 a rdfs:Class ; rdfs:label "SARS-CoV2 orf8 protein binding to human IL17RA"@en ; rdfs:comment "SARS-CoV2 orf8 protein binding to human IL17RA, as evidented by an affinity-purification mass spectrometry experiment" ; rdfs:subClassOf obo:CIDO_0000051 . obo:CIDO_0000088 a rdfs:Class ; rdfs:label "SARS-CoV-2 entry to host cell"@en ; rdfs:comment "A coronavirus-host interaction by which the SARS-CoV-2 virus enters the host cell" ; rdfs:subClassOf obo:CIDO_0000085 , obo:CIDO_0000197 , obo:CIDO_0000286 . obo:VO_0005416 a rdfs:Class ; rdfs:label "mRNA-1273.529"@en ; rdfs:comment "A SARS-CoV-2 mRNA booster vaccine by Moderna that targets the Omicron variant" ; rdfs:subClassOf obo:VO_0005198 . obo:PR_000018241 a rdfs:Class ; rdfs:label "protein zyg-11 homolog B" ; rdfs:comment "A protein that is a translation product of the human ZYG11B gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:CHEBI_60038 a rdfs:Class ; rdfs:label "flavonoid oxoanion" ; rdfs:comment "Any anion arising from deprotonation of at least one OH group in a flavonoid compound." ; rdfs:subClassOf obo:CHEBI_25696 . obo:CIDO_0020158 a rdfs:Class ; rdfs:label "Gnomegen COVID-19-RT-qPCR Detection Kit" ; rdfs:seeAlso ; rdfs:subClassOf obo:CIDO_0000454 . a rdfs:Class ; rdfs:label "Bicyclo Compounds, Heterocyclic [Chemical/Ingredient]" ; rdfs:subClassOf , , . obo:NCBITaxon_1431340 a rdfs:Class ; rdfs:label "SARS bat coronavirus" ; rdfs:subClassOf obo:NCBITaxon_694009 . obo:CHEBI_32632 a rdfs:Class ; rdfs:label "L-methioninium" ; rdfs:comment "The L-enantiomer of methioninium." ; rdfs:subClassOf obo:CHEBI_32646 . obo:VO_0005405 a rdfs:Class ; rdfs:label "AAHI-SC2"@en ; rdfs:comment "A SARS-CoV-2 RNA vaccine by ImmunityBio, Inc." ; rdfs:subClassOf obo:VO_0005198 . a rdfs:Class ; rdfs:label "Indoles [Chemical/Ingredient]" ; rdfs:subClassOf . obo:CHEBI_78324 a rdfs:Class ; rdfs:label "baicalein(1-)" ; rdfs:comment "A flavonoid oxoanion obtained by deprotonation of the hydroxy group at position 7 of baicalein. It is the major microspecies at pH 7.3 (according to Marvin v 6.2.0.)." ; rdfs:subClassOf obo:CHEBI_60038 . obo:VO_0005397 a rdfs:Class ; rdfs:label "GRT-R912"@en ; rdfs:comment "A SARS-CoV-2 RNA vaccine by Gritstone Bio, Inc." ; rdfs:subClassOf obo:VO_0005198 . obo:PR_000004518 a rdfs:Class ; rdfs:label "aurora kinase C" ; rdfs:comment "An aurora kinase that is a translation product of the human AURKC gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000035365 . obo:CHEBI_24921 a rdfs:Class ; rdfs:label "isoquinoline alkaloid" ; rdfs:comment "Any alkaloid that has a structure based on an isoquinoline nucleus. They are derived from the amino acids like tyrosine and phenylalanine." ; rdfs:subClassOf obo:CHEBI_22315 . obo:CIDO_0020147 a rdfs:Class ; rdfs:label "Gene By Gene SARS-CoV-2 Detection Test" ; rdfs:seeAlso ; rdfs:subClassOf obo:CIDO_0000454 . obo:NCBITaxon_260069 a rdfs:Class ; rdfs:label "SARS coronavirus HC/SZ/61/03" ; rdfs:subClassOf obo:NCBITaxon_694009 . obo:CHEBI_51702 a rdfs:Class ; rdfs:label "enoate ester" ; rdfs:comment "An alpha,beta-unsaturated carboxylic ester of general formula R(1)R(2)C=CR(3)-C(=O)OR(4) (R(4) =/= H) in which the ester C=O function is conjugated to a C=C double bond at the alpha,beta position." ; rdfs:subClassOf obo:CHEBI_51737 , obo:CHEBI_78840 . obo:PR_Q9Y2K2 a rdfs:Class ; rdfs:label "serine/threonine-protein kinase SIK3 (human)" ; rdfs:comment "A serine/threonine-protein kinase QSK that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000013573 , obo:PR_000029067 . obo:GO_0051247 a rdfs:Class ; rdfs:label "positive regulation of protein metabolic process" ; rdfs:comment "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving a protein." ; rdfs:subClassOf obo:GO_0010604 , obo:GO_0051173 , obo:GO_0051246 . obo:PR_P21728 a rdfs:Class ; rdfs:label "D(1A) dopamine receptor (human)" ; rdfs:comment "A D(1A) dopamine receptor that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000001175 , obo:PR_000029067 . obo:PR_A0A663DJA2 a rdfs:Class ; rdfs:label "ORF10 protein (SARS-CoV-2)" ; rdfs:comment "A protein that is a translation product of the ORF10 gene in SARS-CoV-2." ; rdfs:subClassOf obo:PR_000050262 . a rdfs:Class ; rdfs:label "Inflammation [Disease/Finding]" ; rdfs:subClassOf . obo:PR_000017938 a rdfs:Class ; rdfs:label "zinc finger protein 503" ; rdfs:comment "A protein that is a translation product of the human ZNF503 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:PR_P70380 a rdfs:Class ; rdfs:label "interleukin-18 (mouse)" ; rdfs:comment "An interleukin-18 that is encoded in the genome of mouse." ; rdfs:subClassOf obo:PR_000001376 , obo:PR_000029032 . a rdfs:Class ; rdfs:label "Thrombocytosis [Disease/Finding]" ; rdfs:subClassOf , . obo:CHEBI_26822 a rdfs:Class ; rdfs:label "sulfide" ; rdfs:comment "Any sulfur molecular entity that involves either covalently bonded or anionic sulfur." ; rdfs:subClassOf obo:CHEBI_26835 . obo:GO_0008360 a rdfs:Class ; rdfs:label "regulation of cell shape" ; rdfs:comment "Any process that modulates the surface configuration of a cell." ; rdfs:subClassOf obo:GO_0050789 , obo:GO_0065008 . obo:VO_0005343 a rdfs:Class ; rdfs:label "COVID-19 subunit vaccine by PT Bio Farma"@en ; rdfs:comment "A SARS-CoV-2 subunit vaccine by PT Bio Farma" ; rdfs:subClassOf obo:VO_0005202 . obo:PR_Q13163 a rdfs:Class ; rdfs:label "dual specificity mitogen-activated protein kinase kinase 5 (human)" ; rdfs:comment "A dual specificity mitogen-activated protein kinase kinase 5 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000010127 , obo:PR_000029067 . obo:NCBITaxon_2509511 a rdfs:Class ; rdfs:label "Sarbecovirus" ; rdfs:subClassOf obo:NCBITaxon_694002 . obo:PR_000007129 a rdfs:Class ; rdfs:label "ephrin type-B receptor 1" ; rdfs:comment "An ephrin receptor that is a translation product of the human EPHB1 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000025845 . obo:CHEBI_50313 a rdfs:Class ; rdfs:label "onium cation" ; rdfs:comment "Mononuclear cations derived by addition of a hydron to a mononuclear parent hydride of the pnictogen, chalcogen and halogen families." ; rdfs:subClassOf obo:CHEBI_50312 . a rdfs:Class ; rdfs:label "Decreased Sympathetic Activity [PE]" ; rdfs:subClassOf . obo:PR_Q5VU43 a rdfs:Class ; rdfs:label "myomegalin (human)" ; rdfs:comment "A myomegalin that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000012476 , obo:PR_000029067 . obo:OBI_0000686 a rdfs:Class ; rdfs:label "material combination objective" ; rdfs:comment "is an objective to obtain an output material that contains several input materials." ; rdfs:subClassOf obo:OBI_0000456 . obo:PR_000005952 a rdfs:Class ; rdfs:label "casein kinase II subunit beta" ; rdfs:comment "A protein that is a translation product of the human CSNK2B gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:CIDO_0000201 a rdfs:Class ; rdfs:label "cytokine storm response to SARS-CoV-2 infection"@en ; rdfs:comment "Cytokine storm is considered to be one of the major causes of Acute respiratory distress syndrome (ARDS) and multiple-organ failure, which often occur rapidly and resulted in death of COVID-19 patients within a short time. Cytokine storm plays an important role in the process of disease aggravation. Ref: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7194613/" ; rdfs:subClassOf obo:CIDO_0000090 . obo:RO_0002608 a rdf:Property ; rdfs:label "process has causal agent" ; rdfs:comment "Inverse of 'causal agent in process'" ; rdfs:range ; rdfs:subPropertyOf obo:RO_0002410 . obo:GO_0016485 a rdfs:Class ; rdfs:label "protein processing" ; rdfs:comment "Any protein maturation process achieved by the cleavage of a peptide bond or bonds within a protein. Protein maturation is the process leading to the attainment of the full functional capacity of a protein." ; rdfs:subClassOf obo:GO_0019538 . obo:CHEBI_49023 a rdfs:Class ; rdfs:label "prostaglandin antagonist" ; rdfs:comment "A compound that inhibits the action of prostaglandins." ; rdfs:subClassOf obo:CHEBI_49020 . obo:GO_0065008 a rdfs:Class ; rdfs:label "regulation of biological quality" ; rdfs:comment "Any process that modulates a qualitative or quantitative trait of a biological quality. A biological quality is a measurable attribute of an organism or part of an organism, such as size, mass, shape, color, etc." ; rdfs:subClassOf obo:GO_0065007 . obo:CHEBI_22658 a rdfs:Class ; rdfs:label "aspartate family amino acid" ; rdfs:comment "An L-alpha-amino acid which is L-aspartic acid or any of the essential amino acids biosynthesised from it (asparagine, lysine, methionine, threonine and isoleucine). A closed class." ; rdfs:subClassOf obo:CHEBI_15705 , obo:CHEBI_83813 . obo:OBI_0000151 a rdfs:Class ; rdfs:label "filter paper" ; rdfs:comment "A device manufacture with the intent to provide a porous unsized paper used for filtering." ; rdfs:subClassOf obo:OBI_0000932 . obo:NCBITaxon_258507 a rdfs:Class ; rdfs:label "SARS coronavirus ShanghaiQXC1" ; rdfs:subClassOf obo:NCBITaxon_694009 . obo:DRON_00022383 a rdfs:Class ; rdfs:label "Mefloquine Oral Tablet" ; rdfs:subClassOf obo:DRON_00000022 . obo:CHEBI_147351 a rdfs:Class ; rdfs:label "angiotensin (1-9) dizwitterion" ; rdfs:comment "A peptide zwitterion that is the dizwitterionic form of angiotensin (1-9) having both carboxy groups deprotonated and the aspartyl amino group and arginine side-chain protonated. It is the major species at pH 7.3." ; rdfs:subClassOf obo:CHEBI_60466 . obo:GO_0044270 a rdfs:Class ; rdfs:label "cellular nitrogen compound catabolic process" ; rdfs:comment "The chemical reactions and pathways resulting in the breakdown of organic and inorganic nitrogenous compounds." ; rdfs:subClassOf obo:GO_0034641 , obo:GO_0044248 . obo:PR_000008210 a rdfs:Class ; rdfs:label "glutathione peroxidase 1" ; rdfs:comment "A protein that is a translation product of the human GPX1 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:NCBITaxon_1289550 a rdfs:Class ; rdfs:label "Coronavirus Mex_CoV-5a" ; rdfs:subClassOf obo:NCBITaxon_366617 . obo:CIDO_0000555 a rdfs:Class ; rdfs:label "TILNTACGVFEVDDT" ; rdfs:comment "A coronavirus epitope that is part of some S protein from HCoV OC43 composed of the following amino acids TILNTACGVFEVDDT" ; rdfs:subClassOf obo:CIDO_0000452 . obo:PR_P04629 a rdfs:Class ; rdfs:label "high affinity nerve growth factor receptor (human)" ; rdfs:comment "A high affinity nerve growth factor receptor that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000011469 , obo:PR_000029067 . obo:HP_0002664 a rdfs:Class ; rdfs:label "Neoplasm" ; rdfs:comment "An organ or organ-system abnormality that consists of uncontrolled autonomous cell-proliferation which can occur in any part of the body as a benign or malignant neoplasm (tumour)." ; rdfs:subClassOf obo:HP_0000118 . obo:VO_0005188 a rdfs:Class ; rdfs:label "Turkovac" ; rdfs:comment "A SARS-CoV-2 inactivated vaccine developed by Health Institutes of Turkey" ; rdfs:subClassOf obo:VO_0005201 , obo:VO_0005266 . obo:GO_0036119 a rdfs:Class ; rdfs:label "response to platelet-derived growth factor" ; rdfs:comment "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a platelet-derived growth factor stimulus." ; rdfs:subClassOf obo:GO_0009719 , obo:GO_0070848 . obo:GO_0009892 a rdfs:Class ; rdfs:label "negative regulation of metabolic process" ; rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways within a cell or an organism." ; rdfs:subClassOf obo:GO_0019222 , obo:GO_0048519 . obo:CHEBI_33937 a rdfs:Class ; rdfs:label "macronutrient" ; rdfs:comment "Any nutrient required in large quantities by organisms throughout their life in order to orchestrate a range of physiological functions. Macronutrients are usually chemical elements (carbon, hydrogen, nitrogen, oxygen, phosphorus and sulfur) that humans consume in the largest quantities. Calcium, sodium, magnesium and potassium are sometimes included as macronutrients because they are required in relatively large quantities compared with other vitamins and minerals." ; rdfs:subClassOf obo:CHEBI_33284 . obo:NCBITaxon_264375 a rdfs:Class ; rdfs:label "SARS coronavirus TW-JC2" ; rdfs:subClassOf obo:NCBITaxon_264370 . obo:CIDO_0000607 a rdfs:Class ; rdfs:label "SARS-CoV2 E protein binding to human BRD2" ; rdfs:comment "SARS-CoV2 E protein binding to human BRD2, as evidented by an affinity-purification mass spectrometry experiment" ; rdfs:subClassOf obo:CIDO_0000046 . obo:VO_0000127 a rdfs:Class ; rdfs:label "aluminum hydroxide vaccine adjuvant" ; rdfs:comment "an aluminum vaccine adjuvant that contains aluminum hydroxide." ; rdfs:subClassOf obo:VO_0000884 . obo:NCBITaxon_228404 a rdfs:Class ; rdfs:label "SARS coronavirus HKU-39849" ; rdfs:subClassOf obo:NCBITaxon_694009 . a rdfs:Class ; rdfs:label "Heterocyclic Compounds with 4 or More Rings [Chemical/Ingredient]" ; rdfs:subClassOf . obo:NCBITaxon_1508223 a rdfs:Class ; rdfs:label "Longquan Rl rat coronavirus" ; rdfs:subClassOf obo:NCBITaxon_2724078 . obo:GO_0035813 a rdfs:Class ; rdfs:label "regulation of renal sodium excretion" ; rdfs:comment "Any process that modulates the amount of sodium excreted in urine over a unit of time." ; rdfs:subClassOf obo:GO_0044057 , obo:GO_0044062 . obo:CIDO_0000540 a rdfs:Class ; rdfs:label "SAIEDILFSKLVTSG" ; rdfs:comment "A coronavirus epitope that is part of some S protein from HCoV 229E composed of the following amino acids SAIEDILFSKLVTSG" ; rdfs:subClassOf obo:CIDO_0000451 . obo:CIDO_0020280 a rdfs:Class ; rdfs:label "SARS-CoV-2 RNA DETECTR Assay" ; rdfs:seeAlso ; rdfs:subClassOf obo:CIDO_0000454 . obo:GO_0052126 a rdfs:Class ; rdfs:label "movement in host environment" ; rdfs:comment "The directed movement of an organism or motile cell on, within or near its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction." ; rdfs:subClassOf obo:GO_0044419 . obo:PR_P30085 a rdfs:Class ; rdfs:label "UMP-CMP kinase (human)" ; rdfs:comment "A UMP-CMP kinase that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000005624 , obo:PR_000029067 . obo:PR_Q9NQC3 a rdfs:Class ; rdfs:label "reticulon-4 (human)" ; rdfs:comment "A reticulon-4 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000014348 , obo:PR_000029067 . obo:CIDO_0020137 a rdfs:Class ; rdfs:label "Exact Sciences SARS-CoV-2 (N gene detection) Test" ; rdfs:seeAlso ; rdfs:subClassOf obo:CIDO_0000454 . obo:CIDO_0000969 a rdfs:Class ; rdfs:label "SARS-CoV2 orf10 protein binding to human THTPA" ; rdfs:comment "SARS-CoV2 orf10 protein binding to human THTPA, as evidented by an affinity-purification mass spectrometry experiment" ; rdfs:subClassOf obo:CIDO_0000050 . obo:CHEBI_33608 a rdfs:Class ; rdfs:label "hydrogen molecular entity" ; rdfs:subClassOf obo:CHEBI_33674 . obo:CHEBI_147285 a rdfs:Class ; rdfs:label "EC 3.4.22.69 (SARS coronavirus main proteinase) inhibitor" ; rdfs:comment "An EC 3.4.22.* (cysteine endopeptidase) inhibitor that interferes with the action of SARS coronavirus main proteinase (EC 3.4.22.69)." ; rdfs:subClassOf obo:CHEBI_76796 . a rdfs:Class ; rdfs:label "Cryoglobulinemia [Disease/Finding]" ; rdfs:subClassOf , . obo:CIDO_0000328 a rdfs:Class ; rdfs:label "NLLLQYGSFCTQLNR"@en ; rdfs:subClassOf obo:CIDO_0000314 . obo:CHEBI_32955 a rdfs:Class ; rdfs:label "epoxide" ; rdfs:comment "Any cyclic ether in which the oxygen atom forms part of a 3-membered ring." ; rdfs:subClassOf obo:CHEBI_37407 . obo:GO_0032309 a rdfs:Class ; rdfs:label "icosanoid secretion" ; rdfs:comment "The controlled release of icosanoids, any of a group of C20 polyunsaturated fatty acids from a cell or a tissue." ; rdfs:subClassOf obo:GO_0006810 , obo:GO_0071715 . obo:NCBITaxon_31626 a rdfs:Class ; rdfs:label "Avian infectious bronchitis virus (strain UK/123/82)" ; rdfs:subClassOf obo:NCBITaxon_11120 . obo:NCBITaxon_321149 a rdfs:Class ; rdfs:label "SARS coronavirus BJ202" ; rdfs:subClassOf obo:NCBITaxon_694009 . obo:CHEBI_63114 a rdfs:Class ; rdfs:label "sphingosine-1-phosphate receptor agonist" ; rdfs:comment "An agonist that binds to and activates sphingosine 1-phosphate receptors." ; rdfs:subClassOf obo:CHEBI_48705 . obo:NCBITaxon_296837 a rdfs:Class ; rdfs:label "SARS coronavirus PC4-115" ; rdfs:subClassOf obo:NCBITaxon_694009 . obo:GO_0046488 a rdfs:Class ; rdfs:label "phosphatidylinositol metabolic process" ; rdfs:comment "The chemical reactions and pathways involving phosphatidylinositol, any glycophospholipid in which a sn-glycerol 3-phosphate residue is esterified to the 1-hydroxyl group of 1D-myo-inositol." ; rdfs:subClassOf obo:GO_0006650 . obo:PR_Q9H4F8 a rdfs:Class ; rdfs:label "SPARC-related modular calcium-binding protein 1 (human)" ; rdfs:comment "A SPARC-related modular calcium-binding protein 1 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000015289 , obo:PR_000029067 . obo:NCBITaxon_1269299 a rdfs:Class ; rdfs:label "Coronavirus BtCoV/BRAP103/Mol_cur/BRA/2009" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:NCBITaxon_2748747 a rdfs:Class ; rdfs:label "Pangolin coronavirus GZ5-2" ; rdfs:subClassOf obo:NCBITaxon_2720068 . obo:OBI_0002774 a rdfs:Class ; rdfs:label "platelet-poor plasma specimen"@en ; rdfs:comment "A blood plasma specimen that is the output of some platelet-poor plasma preparation and is the portion of plasma that contains fewer than 10,000 platelets per microliter."@en ; rdfs:subClassOf obo:OBI_0100016 . obo:CHEBI_75769 a rdfs:Class ; rdfs:label "B vitamin" ; rdfs:comment "Any member of the group of eight water-soluble vitamins originally thought to be a single compound (vitamin B) that play important roles in cell metabolism. The group comprises of vitamin B1, B2, B3, B5, B6, B7, B9, and B12 (Around 20 other compounds were once thought to be B vitamins but are no longer classified as such)." ; rdfs:subClassOf obo:CHEBI_35352 , obo:CHEBI_36963 . obo:UBERON_0006562 a rdfs:Class ; rdfs:label "pharynx" ; rdfs:comment "The pharynx is the part of the digestive system immediately posterior to the mouth[GO]." ; rdfs:subClassOf obo:UBERON_0004921 . obo:NCBITaxon_11150 a rdfs:Class ; rdfs:label "Porcine transmissible gastroenteritis coronavirus strain FS772/70" ; rdfs:subClassOf obo:NCBITaxon_11149 . a rdfs:Class ; rdfs:label "Cholinergic Muscarinic Receptor Interactions [MoA]" ; rdfs:subClassOf , . obo:CHEBI_26912 a rdfs:Class ; rdfs:label "oxolanes" ; rdfs:comment "Any oxacycle having an oxolane (tetrahydrofuran) skeleton." ; rdfs:subClassOf obo:CHEBI_25693 , obo:CHEBI_38104 . obo:HP_0004751 a rdfs:Class ; rdfs:label "Paroxysmal ventricular tachycardia" ; rdfs:comment "Episodes of ventricular tachycardia that have a sudden onset and ending." ; rdfs:subClassOf obo:HP_0004756 . obo:NCBITaxon_681858 a rdfs:Class ; rdfs:label "Kenya bat coronavirus BtKY11" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:PR_000000005 a rdfs:Class ; rdfs:label "TGF-beta receptor type-2" ; rdfs:comment "A protein that is a translation product of the human TGFBR2 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:OBI_0002520 a rdfs:Class ; rdfs:label "heart specimen" ; rdfs:comment "A specimen that is derived from heart." ; rdfs:subClassOf obo:OBI_0001479 . obo:NCBITaxon_393045 a rdfs:Class ; rdfs:label "Bat coronavirus HKU6" ; rdfs:subClassOf obo:NCBITaxon_366617 . a rdfs:Class ; rdfs:label "West Nile Fever [Disease/Finding]" ; rdfs:subClassOf , . obo:CIDO_0000047 a rdfs:Class ; rdfs:label "SARS-CoV-2 Nsp5 protein interaction with host protein"@en ; rdfs:comment "A molecular interaction that has participant of the SARS-CoV-2 Nsp5 protein and a host protein" ; rdfs:subClassOf obo:CIDO_0000348 . obo:NCBITaxon_231433 a rdfs:Class ; rdfs:label "Rat coronavirus (strain NJ)" ; rdfs:subClassOf obo:NCBITaxon_31632 . obo:DOID_12139 a rdfs:Class ; rdfs:label "dysthymic disorder" ; rdfs:comment "A mood disorder that involves the presence of a low mood almost daily over a span of at least two years." ; rdfs:subClassOf obo:DOID_3324 . obo:IDO_0000503 a rdfs:Class ; rdfs:label "infectious disease pandemic"@en ; rdfs:comment "A process in which multiple infectious disease epidemics of the same type of infectious disease unfold over overlapping periods of time and affect organism populations located in different geographic regions, including different countries and continents."@en ; rdfs:subClassOf obo:BFO_0000015 . obo:CHEBI_32486 a rdfs:Class ; rdfs:label "L-phenylalaninate" ; rdfs:comment "An optically active form of phenylalaninate having L-configuration." ; rdfs:subClassOf obo:CHEBI_32504 , obo:CHEBI_59814 . obo:CHEBI_76727 a rdfs:Class ; rdfs:label "EC 1.2.* (oxidoreductase acting on donor aldehyde/oxo group) inhibitor" ; rdfs:comment "An oxidoreductase inhibitor which interferes with the action of an oxidoreductase acting on the aldehyde or oxo group of donors (EC 1.2.*.*)." ; rdfs:subClassOf obo:CHEBI_76725 . obo:NCBITaxon_562957 a rdfs:Class ; rdfs:label "Tai Forest coronavirus" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:PR_P42685 a rdfs:Class ; rdfs:label "tyrosine-protein kinase FRK (human)" ; rdfs:comment "A tyrosine-protein kinase FRK that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000007664 , obo:PR_000029067 . obo:CIDO_0020326 a rdfs:Class ; rdfs:label "Visby Medical COVID-19" ; rdfs:seeAlso ; rdfs:subClassOf obo:CIDO_0000454 . obo:NCBITaxon_9673 a rdfs:Class ; rdfs:label "Viverridae" ; rdfs:subClassOf obo:NCBITaxon_379583 . obo:NCBITaxon_1346299 a rdfs:Class ; rdfs:label "Betacoronavirus BtCoV/Rhi_eur/BB99-04/BGR/2009" ; rdfs:subClassOf obo:NCBITaxon_696098 . obo:CHEBI_24621 a rdfs:Class ; rdfs:label "hormone" ; rdfs:comment "Originally referring to an endogenous compound that is formed in specialized organ or group of cells and carried to another organ or group of cells, in the same organism, upon which it has a specific regulatory function, the term is now commonly used to include non-endogenous, semi-synthetic and fully synthetic analogues of such compounds." ; rdfs:subClassOf obo:CHEBI_33280 , obo:CHEBI_48705 . obo:CHEBI_80025 a rdfs:Class ; rdfs:label "Salinomycin" ; rdfs:subClassOf obo:CHEBI_26188 , obo:CHEBI_72600 . a rdfs:Class ; rdfs:label "Conjunctival Diseases [Disease/Finding]" ; rdfs:subClassOf . obo:CIDO_0000487 a rdfs:Class ; rdfs:label "LVPQENYSSIRFASV" ; rdfs:comment "A coronavirus epitope that is part of some S protein from HCoV OC43 composed of the following amino acids LVPQENYSSIRFASV" ; rdfs:subClassOf obo:CIDO_0000452 . obo:PR_P13236 a rdfs:Class ; rdfs:label "C-C motif chemokine 4 (human)" ; rdfs:comment "A C-C motif chemokine 4 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000002124 , obo:PR_000029067 . obo:CIDO_0001216 a rdfs:Class ; rdfs:label "Multiple Real-Time PCR Kit for Detection of 2019-nCoV. (Beijing NaGene Diagnosis Reagent Co., Ltd.)" ; rdfs:comment "Poduct storage conditions and expiration date: Store in the dark at -20 ± 5 ℃, the validity period is tentatively set for 6 months." ; rdfs:subClassOf obo:CIDO_0000021 . obo:HP_0100626 a rdfs:Class ; rdfs:label "Chronic hepatic failure" ; rdfs:subClassOf obo:HP_0025032 . obo:PR_P47869 a rdfs:Class ; rdfs:label "gamma-aminobutyric acid receptor subunit alpha-2 (human)" ; rdfs:comment "A gamma-aminobutyric acid receptor subunit alpha-2 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000007767 , obo:PR_000029067 . a rdfs:Class ; rdfs:label "Propafenone [Chemical/Ingredient]" ; rdfs:subClassOf . obo:DOID_0070090 a rdfs:Class ; rdfs:label "schizophrenia 14" ; rdfs:comment "A schizophrenia that has_material_basis_in a mutation on chromosome 2q32.1." ; rdfs:subClassOf obo:DOID_0050177 , obo:DOID_5419 . obo:CHEBI_60090 a rdfs:Class ; rdfs:label "7-hydroxyflavon-3-olate" ; rdfs:comment "Conjugate base of a 7-hydroxyflavonol compound arising from selective deprotonation of the 3-hydroxy group; major species at pH 7.3." ; rdfs:subClassOf obo:CHEBI_60038 . obo:NCBITaxon_9989 a rdfs:Class ; rdfs:label "Rodentia" ; rdfs:subClassOf obo:NCBITaxon_314147 . obo:VO_0005181 a rdfs:Class ; rdfs:label "chimpanzee adenovirus Oxford1 vaccine vector"@en ; rdfs:comment "A chimpanzee adenovirus vaccine vector that patented by Oxford and derived from ChAd serotype Y25 that exchanges the native E4 orf4, orf6 and orf6/7 genes for those from HAdV-C5" ; rdfs:subClassOf obo:VO_0001055 . obo:PR_000015082 a rdfs:Class ; rdfs:label "zinc transporter 9" ; rdfs:comment "A protein that is a translation product of the human SLC30A9 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:CIDO_0000834 a rdfs:Class ; rdfs:label "SARS-CoV2 nsp13 protein binding to human CLIP4" ; rdfs:comment "SARS-CoV2 nsp13 protein binding to human CLIP4, as evidented by an affinity-purification mass spectrometry experiment" ; rdfs:subClassOf obo:CIDO_0000058 . obo:CHEBI_16183 a rdfs:Class ; rdfs:label "methane" ; rdfs:comment "A one-carbon compound in which the carbon is attached by single bonds to four hydrogen atoms. It is a colourless, odourless, non-toxic but flammable gas (b.p. -161degreeC)." ; rdfs:subClassOf obo:CHEBI_138675 , obo:CHEBI_18310 , obo:CHEBI_37176 , obo:CHEBI_64708 . obo:CHEBI_78608 a rdfs:Class ; rdfs:label "alpha-amino acid zwitterion" ; rdfs:comment "An amino acid zwitterion obtained by transfer of a proton from the carboxy to the amino group of any alpha-amino acid; major species at pH 7.3." ; rdfs:subClassOf obo:CHEBI_35238 . obo:OPMI_0000527 a rdfs:Class ; rdfs:label "condition occurrence"@en ; rdfs:comment "A process event where a person presents a disease or medical condition stated as a diagnosis, a sign, or a symptom, which is either observed by a Provider or reported by the patient." ; rdfs:subClassOf obo:BFO_0000015 . obo:NCBITaxon_681875 a rdfs:Class ; rdfs:label "Kenya bat coronavirus BtKY30" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:UBERON_0001323 a rdfs:Class ; rdfs:label "tibial nerve" ; rdfs:comment "The tibial nerve is a branch of the sciatic nerve. The tibial nerve passes through the popliteal fossa to pass below the arch of soleus. In the popliteal fossa the nerve gives off branches to gastrocnemius, popliteus, soleus and plantaris muscles, an articular branch to the knee joint, and a cutaneous branch that will become the sural nerve. The sural nerve is joined by fibres from the common peroneal nerve and runs down the calf to supply the lateral side of the foot. Below the soleus muscle the nerve lies close to the tibia and supplies the tibialis posterior, the flexor digitorum longus and the flexor hallucis longus. The nerve passes into the foot running posterior to the medial malleolus. Here it is bound down by the flexor retinaculum in company with the posterior tibial artery. [WP,unvetted]." ; rdfs:subClassOf obo:UBERON_0000477 . obo:NCBITaxon_2042558 a rdfs:Class ; rdfs:label "Coronavirus PREDICT CoV-33" ; rdfs:subClassOf obo:NCBITaxon_366617 . obo:CHEBI_33696 a rdfs:Class ; rdfs:label "nucleic acid" ; rdfs:comment "A macromolecule made up of nucleotide units and hydrolysable into certain pyrimidine or purine bases (usually adenine, cytosine, guanine, thymine, uracil), D-ribose or 2-deoxy-D-ribose and phosphoric acid." ; rdfs:subClassOf obo:CHEBI_33839 . a rdfs:Class ; rdfs:label "HYDROXYCHLOROQUINE" ; rdfs:subClassOf . obo:NCBITaxon_1346315 a rdfs:Class ; rdfs:label "Betacoronavirus BtCoV/Rhi_hip/Slo53/SLO/2009" ; rdfs:subClassOf obo:NCBITaxon_696098 . obo:CHEBI_32619 a rdfs:Class ; rdfs:label "L-leucinate" ; rdfs:comment "The L-enantiomer of leucinate." ; rdfs:subClassOf obo:CHEBI_32627 , obo:CHEBI_59814 . obo:CIDO_0020336 a rdfs:Class ; rdfs:label "xMAP SARS-CoV-2 Multi-Antigen IgG Assay" ; rdfs:seeAlso ; rdfs:subClassOf obo:CIDO_0000454 . obo:HP_0100749 a rdfs:Class ; rdfs:label "Chest pain" ; rdfs:comment "An unpleasant sensation characterized by physical discomfort (such as pricking, throbbing, or aching) localized to the chest." ; rdfs:subClassOf obo:HP_0012531 . obo:HP_0001618 a rdfs:Class ; rdfs:label "Dysphonia" ; rdfs:comment "An impairment in the ability to produce voice sounds." ; rdfs:subClassOf obo:HP_0000118 , obo:HP_0011446 . obo:CHEBI_25435 a rdfs:Class ; rdfs:label "mutagen" ; rdfs:comment "An agent that increases the frequency of mutations above the normal background level, usually by interacting directly with DNA and causing it damage, including base substitution." ; rdfs:subClassOf obo:CHEBI_50902 . obo:PR_Q9NR30 a rdfs:Class ; rdfs:label "nucleolar RNA helicase 2 (human)" ; rdfs:comment "A nucleolar RNA helicase 2 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000006359 , obo:PR_000029067 . obo:CIDO_0020115 a rdfs:Class ; rdfs:label "Diazyme DZ-Lite SARS-CoV-2 IgG CLIA Kit" ; rdfs:seeAlso ; rdfs:subClassOf obo:CIDO_0000454 . obo:PR_P07498 a rdfs:Class ; rdfs:label "kappa-casein (human)" ; rdfs:comment "A kappa-casein that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000005942 , obo:PR_000029067 . obo:CHEBI_46701 a rdfs:Class ; rdfs:label "pyrrolidinemonocarboxylic acid" ; rdfs:subClassOf obo:CHEBI_25384 , obo:CHEBI_46767 . a rdfs:Class ; rdfs:label "Chlorpromazine Hydrochloride [Chemical/Ingredient]" ; rdfs:subClassOf . obo:PR_000008247 a rdfs:Class ; rdfs:label "glutamate receptor ionotropic, NMDA 2B" ; rdfs:comment "An ionotropic glutamate receptor protein that is a translation product of the human GRIN2B gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000044666 . obo:CIDO_0020066 a rdfs:Class ; rdfs:label "Boston Heart COVID-19 RT-PCR Test" ; rdfs:seeAlso ; rdfs:subClassOf obo:CIDO_0000454 . obo:OPMI_0000282 a rdfs:Class ; rdfs:label "medical condition"@en ; rdfs:comment "The medical state or condition of a patient" ; rdfs:subClassOf obo:BFO_0000017 . a rdfs:Class ; rdfs:label "Decreased Peripheral Nervous System Acetylcholine Activity [PE]" ; rdfs:subClassOf . obo:CHEBI_143014 a rdfs:Class ; rdfs:label "ML240" ; rdfs:comment "A member of the class of quinazolines that is quinazoline which is substituted at positions 2, 5 and 8 by 2-amino-1H-benzimidazol-1-yl, benzylnitrilo and methoxy groups, respectively. It is a ATP-competetive inhibitor of AAA ATPase p97, also known as valosin-containing protein (VCP)." ; rdfs:subClassOf obo:CHEBI_22715 , obo:CHEBI_33860 , obo:CHEBI_35618 , obo:CHEBI_38530 , obo:CHEBI_50994 , obo:CHEBI_50995 . obo:NCBITaxon_9526 a rdfs:Class ; rdfs:label "Catarrhini" ; rdfs:subClassOf obo:NCBITaxon_314293 . obo:PR_P29320 a rdfs:Class ; rdfs:label "ephrin type-A receptor 3 (human)" ; rdfs:comment "An ephrin type-A receptor 3 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000007123 , obo:PR_000029067 . obo:NCBITaxon_1146855 a rdfs:Class ; rdfs:label "Bat coronavirus M.nattereri/UK/Sav/1092B" ; rdfs:subClassOf obo:NCBITaxon_366617 . obo:CHEBI_35352 a rdfs:Class ; rdfs:label "organonitrogen compound" ; rdfs:comment "Any heteroorganic entity containing at least one carbon-nitrogen bond." ; rdfs:subClassOf obo:CHEBI_33285 , obo:CHEBI_51143 . obo:CIDO_0000581 a rdfs:Class ; rdfs:label "SARS-CoV-2 Nsp4 protein interaction with host protein"@en ; rdfs:comment "A molecular interaction that has participant of the SARS-CoV-2 Nsp4 protein and a host protein" ; rdfs:subClassOf obo:CIDO_0000348 . obo:PR_Q9H6F5 a rdfs:Class ; rdfs:label "coiled-coil domain-containing protein 86 (human)" ; rdfs:comment "A coiled-coil domain-containing protein 86 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000029067 , obo:PR_000029340 . obo:PR_000013883 a rdfs:Class ; rdfs:label "renin" ; rdfs:comment "An angiotensinogenase that is a translation product of the human REN gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000050025 . obo:GO_0001975 a rdfs:Class ; rdfs:label "response to amphetamine" ; rdfs:comment "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an amphetamine stimulus. Amphetamines consist of a group of compounds related to alpha-methylphenethylamine." ; rdfs:subClassOf obo:GO_0010243 . obo:HP_0011701 a rdfs:Class ; rdfs:label "Multifocal atrial tachycardia" ; rdfs:comment "Multifocal atrial tachycardia is a rare supraventricular arrhythmia in neonates and young infants that is characterized by multiple P waves with varying P wave morphology and is usually asymptomatic." ; rdfs:subClassOf obo:HP_0001692 . obo:DRON_00025278 a rdfs:Class ; rdfs:label "Methylprednisolone / Neomycin Topical Cream" ; rdfs:subClassOf obo:DRON_00000017 . a rdfs:Class ; rdfs:label "Cardiac Output, Low [Disease/Finding]" ; rdfs:subClassOf , . obo:VO_0005108 a rdfs:Class ; rdfs:label "SARS MA-ExoN vaccine" ; rdfs:comment "A SARS recombinant vector vaccine that is made from of the highly attenuated modified vaccinia virus Ankara (MVA) containing the gene encoding full-length SARS-CoV S" ; rdfs:subClassOf obo:VO_0012183 . obo:NCBITaxon_1503280 a rdfs:Class ; rdfs:label "BtMf-AlphaCoV/GD2012" ; rdfs:subClassOf obo:NCBITaxon_694001 . obo:HP_0033362 a rdfs:Class ; rdfs:label "Recurrent coughing spasms" ; rdfs:comment "Repeated occurrence of episodes of coughing, with each episode consisting of at least five minutes of continuous coughing." ; rdfs:subClassOf obo:HP_0012735 . obo:HP_0003193 a rdfs:Class ; rdfs:label "Allergic rhinitis" ; rdfs:comment "It is characterized by one or more symptoms including sneezing, itching, nasal congestion, and rhinorrhea." ; rdfs:subClassOf obo:HP_0000366 , obo:HP_0012393 . obo:HP_0032325 a rdfs:Class ; rdfs:label "Lacunar stroke" ; rdfs:comment "A stroke related to a small infarct (2-20 mm in diameter) in the deep cerebral white matter, basal ganglia, or pons, that is presumed to result from the occlusion of a single small perforating artery supplying the subcortical areas of the brain." ; rdfs:subClassOf obo:HP_0002140 . obo:PR_000005930 a rdfs:Class ; rdfs:label "macrophage colony-stimulating factor 1" ; rdfs:comment "A protein that is a translation product of the human CSF1 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:CHEBI_62732 a rdfs:Class ; rdfs:label "aromatic ester" ; rdfs:comment "An ester where the ester linkage is bonded directly to an aromatic system." ; rdfs:subClassOf obo:CHEBI_33659 , obo:CHEBI_35701 . obo:CIDO_0000302 a rdfs:Class ; rdfs:label "SARS-CoV epitope"@en ; rdfs:subClassOf obo:CIDO_0000300 . obo:OBI_0002746 a rdfs:Class ; rdfs:label "induced sputum specimen" ; rdfs:comment "A sputum specimen that is collected from an organism following its inhalation of a nebulized salt solution." ; rdfs:subClassOf obo:OBI_0002508 . obo:CHEBI_17664 a rdfs:Class ; rdfs:label "alkylaminium" ; rdfs:comment "A primary ammonium ion obtained by protonation of the amino goup of any alkylamine; major species at pH 7.3." ; rdfs:subClassOf obo:CHEBI_65296 . obo:CIDO_0020219 a rdfs:Class ; rdfs:label "Omni COVID-19 Assay by RT-PCR" ; rdfs:seeAlso ; rdfs:subClassOf obo:CIDO_0000454 . obo:PR_000029381 a rdfs:Class ; rdfs:label "probable ATP-dependent RNA helicase DDX10" ; rdfs:comment "A protein that is a translation product of the human DDX10 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:HP_0100326 a rdfs:Class ; rdfs:label "Immunologic hypersensitivity" ; rdfs:comment "Immunological states where the immune system produces harmful responses upon reexposure to sensitising antigens." ; rdfs:subClassOf obo:HP_0010978 . obo:PR_O14578 a rdfs:Class ; rdfs:label "citron Rho-interacting kinase (human)" ; rdfs:comment "A citron Rho-interacting kinase that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000005504 , obo:PR_000029067 . obo:NCBITaxon_398809 a rdfs:Class ; rdfs:label "TGEV Miller M6" ; rdfs:subClassOf obo:NCBITaxon_33737 . obo:OPMI_0000494 a rdfs:Class ; rdfs:label "non-hospital institution visit"@en ; rdfs:comment "A visit to a dedicated institution for reasons of poor health, at a Care Site, long-term or permanently, with no physician but possibly other Providers permanently available to deliver service around the clock" ; rdfs:subClassOf obo:OPMI_0000482 . obo:PR_000003063 a rdfs:Class ; rdfs:label "SYK/ZAP-70 family tyrosine-protein kinase" ; rdfs:comment "A protein that is a translation product of the human SYK or ZAP70 genes, 1:1 orthologs thereof, or a semi-ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:PR_P26676 a rdfs:Class ; rdfs:label "RNA-directed RNA polymerase L (HPIV-2)" ; rdfs:subClassOf obo:PR_000000001 . obo:CHEBI_33635 a rdfs:Class ; rdfs:label "polycyclic compound" ; rdfs:subClassOf obo:CHEBI_33595 . obo:CIDO_0001205 a rdfs:Class ; rdfs:label "Multiple Real-Time PCR Kit for Detection of 2019-nCoV. (Shanghai BioGerm Medical Technology Co., Ltd.)" ; rdfs:comment "Manufacturor: Shanghai BioGerm Medical Technology Co., Ltd. 上海伯杰医疗科技有限公司" ; rdfs:subClassOf obo:CIDO_0000021 . obo:GO_1901566 a rdfs:Class ; rdfs:label "organonitrogen compound biosynthetic process" ; rdfs:comment "The chemical reactions and pathways resulting in the formation of organonitrogen compound." ; rdfs:subClassOf obo:GO_1901564 , obo:GO_1901576 . obo:PR_000005270 a rdfs:Class ; rdfs:label "cyclin-dependent kinase-like 2" ; rdfs:comment "A CDK2-related kinase that is a translation product of the human CDKL2 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000003270 . obo:PR_000014686 a rdfs:Class ; rdfs:label "corticosteroid-binding globulin" ; rdfs:comment "A serpin that is a translation product of the human SERPINA6 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000025875 . obo:CHEBI_26605 a rdfs:Class ; rdfs:label "saponin" ; rdfs:comment "A glycoside that is a compound containing one or more hydrophilic glycoside moieties combined with a lipophilic triterpenoid or steroid derivative. Found in particular abundance in plant species." ; rdfs:subClassOf obo:CHEBI_24400 . obo:PR_000007123 a rdfs:Class ; rdfs:label "ephrin type-A receptor 3" ; rdfs:comment "An ephrin receptor that is a translation product of the human EPHA3 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000025845 . a rdfs:Class ; rdfs:label "Cardiac Glycosides [Chemical/Ingredient]" ; rdfs:subClassOf , . obo:PR_P0DTC2 a rdfs:Class ; rdfs:label "spike glycoprotein (SARS-CoV-2)" ; rdfs:comment "A protein that is a translation product of the S gene in SARS-CoV-2." ; rdfs:subClassOf obo:PR_000050262 , obo:VO_0004988 . obo:PR_000030426 a rdfs:Class ; rdfs:label "histone-lysine N-methyltransferase NSD2" ; rdfs:comment "A protein that is a translation product of the human NSD2 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:CHEBI_32532 a rdfs:Class ; rdfs:label "histidinium(2+)" ; rdfs:subClassOf obo:CHEBI_33719 . obo:PR_000006277 a rdfs:Class ; rdfs:label "death-associated protein kinase 2" ; rdfs:comment "A death-associated protein kinase that is a translation product of the human DAPK2 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000029896 . obo:NCBITaxon_681864 a rdfs:Class ; rdfs:label "Kenya bat coronavirus BtKY18" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:NCBITaxon_1415837 a rdfs:Class ; rdfs:label "Bat SARS-like coronavirus Rs4079" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:CIDO_0000390 a rdfs:Class ; rdfs:label "BALB/c mouse"@en ; rdfs:subClassOf obo:NCBITaxon_10090 . obo:CHEBI_33839 a rdfs:Class ; rdfs:label "macromolecule" ; rdfs:comment "A macromolecule is a molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass." ; rdfs:subClassOf obo:CHEBI_23367 , obo:CHEBI_36357 . obo:CIDO_0000402 a rdfs:Class ; rdfs:label "SARS-CoV-2 P.1 virus"@en ; rdfs:comment """A SARS-CoV-2 Gamma variant virus with the majority of the following mutations: orf1ab:S1188L, orf1ab:K1795Q, del:11288:9, S:L18F, S:T20N, S:P26S, S:D138Y, S:R190S, S:K417T, S:E484K, S:N501Y, S:H655Y, S:T1027I, orf3a:G174C, orf8:E92K, N:P80R""" ; rdfs:subClassOf obo:CIDO_0000377 , obo:CIDO_0000406 . obo:NCBITaxon_1788487 a rdfs:Class ; rdfs:label "Rhinolophus bat coronavirus BtCoV/3992-1" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:CIDO_0001018 a rdfs:Class ; rdfs:label "Abivertinib" ; rdfs:subClassOf obo:CHEBI_23367 . a rdfs:Class ; rdfs:label "Tachycardia, Ventricular [Disease/Finding]" ; rdfs:subClassOf . obo:NCBITaxon_550973 a rdfs:Class ; rdfs:label "Bat coronavirus M.aus/Australia/CoV088/2007" ; rdfs:subClassOf obo:NCBITaxon_366617 . obo:CHEBI_51959 a rdfs:Class ; rdfs:label "organic tricyclic compound" ; rdfs:subClassOf obo:CHEBI_51958 . obo:CIDO_0001220 a rdfs:Class ; rdfs:label "SARS-CoV-2 Nucleic Acid Detection Kit (hybrid capture immunofluorescence method)) (Anbio (Xiamen) Biotechnology Co., Ltd.)" ; rdfs:comment "Poduct storage conditions and expiration date: Store at 2~30°C in a dry place away from light and heat. The validity period of the kit is tentatively set for 6 months." ; rdfs:subClassOf obo:CIDO_0000021 . obo:NCBITaxon_9836 a rdfs:Class ; rdfs:label "Camelus" ; rdfs:subClassOf obo:NCBITaxon_9835 . obo:NCBITaxon_11122 a rdfs:Class ; rdfs:label "Avian infectious bronchitis virus (strain Beaudette)" ; rdfs:subClassOf obo:NCBITaxon_11120 . obo:HP_0032101 a rdfs:Class ; rdfs:label "Unusual infection" ; rdfs:comment "A type of infection that is regarded as a sign of a pathological susceptibility to infection. There are five general subtypes. (i) Opportunistic infection, meaning infection by a pathogen that is not normally able to cause infection in a healthy host (e.g., pneumonia by Pneumocystis jirovecii or CMV); (ii) Unusual location (focus) of an infection (e.g., an aspergillus brain abscess); (iii) a protracted course or lack of adequate response to treatment (e.g., chronic rhinosinusitis); (iv) Unusual severity or intensity of an infection; and (v) unusual recurrence of infections." ; rdfs:subClassOf obo:HP_0010978 . obo:CHEBI_149552 a rdfs:Class ; rdfs:label "emetic" ; rdfs:comment "Any agent that induces nausea and vomiting." ; rdfs:subClassOf obo:CHEBI_23888 . obo:PR_P36507 a rdfs:Class ; rdfs:label "dual specificity mitogen-activated protein kinase kinase 2 (human)" ; rdfs:comment "A dual specificity mitogen-activated protein kinase kinase 2 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000010126 , obo:PR_000029067 . obo:OPMI_0000538 a rdfs:Class ; rdfs:label "discharge diagnosis status"@en ; rdfs:comment "A discharge diagnosis is a final diagnosis given a patient before release from the hospital after all testing, surgery, and workup are complete." ; rdfs:subClassOf obo:OPMI_0000533 . obo:NCBITaxon_2492656 a rdfs:Class ; rdfs:label "Alphacoronavirus Bat-CoV/P.kuhlii/Italy/206645-41/2011" ; rdfs:subClassOf obo:NCBITaxon_2727852 . obo:CHEBI_15366 a rdfs:Class ; rdfs:label "acetic acid" ; rdfs:comment "A simple monocarboxylic acid containing two carbons." ; rdfs:subClassOf obo:CHEBI_25384 . obo:NCBITaxon_694009 a rdfs:Class ; rdfs:label "Severe acute respiratory syndrome-related coronavirus" ; rdfs:subClassOf obo:NCBITaxon_2509511 , obo:NCBITaxon_694002 . obo:NCBITaxon_1699354 a rdfs:Class ; rdfs:label "Rousettus Bat Betacoronavirus strain ML_44I" ; rdfs:subClassOf obo:NCBITaxon_696098 . obo:CIDO_0020177 a rdfs:Class ; rdfs:label "IntelliPlex SARS-CoV-2 Detection Kit" ; rdfs:seeAlso ; rdfs:subClassOf obo:CIDO_0000454 . a rdfs:Class ; rdfs:label "Naphthalenes [Chemical/Ingredient]" ; rdfs:subClassOf . obo:CIDO_0000638 a rdfs:Class ; rdfs:label "K1655N in SARS-CoV-2 pp1a protein" ; rdfs:comment "An AA mutation or AA variant that has mutated an amino acid at position 1655 into a asparagine in pp1a." ; rdfs:subClassOf obo:CIDO_0001074 . obo:CHEBI_32627 a rdfs:Class ; rdfs:label "leucinate" ; rdfs:comment "An alpha-amino-acid anion that is the conjugate base of leucine, arising from deprotonation of the carboxy group." ; rdfs:subClassOf obo:CHEBI_33558 , obo:CHEBI_63471 . a rdfs:Class ; rdfs:label "Respiratory/Pulmonary Activity Alteration [PE]" ; rdfs:subClassOf . obo:PR_Q7Z5G4 a rdfs:Class ; rdfs:label "golgin subfamily A member 7 (human)" ; rdfs:comment "A golgin subfamily A member 7 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000008135 , obo:PR_000029067 . obo:GO_0003106 a rdfs:Class ; rdfs:label "negative regulation of glomerular filtration by angiotensin" ; rdfs:comment "The process in which angiotensin directly decreases the rate of glomerular filtration in the kidney. Glomerular filtration is the processs whereby blood is filtered by the glomerulus into the renal tubule." ; rdfs:subClassOf obo:GO_0003083 . obo:CHEBI_86328 a rdfs:Class ; rdfs:label "antifungal agrochemical" ; rdfs:comment "Any substance used in acriculture, horticulture, forestry, etc. for its fungicidal properties." ; rdfs:subClassOf obo:CHEBI_24127 , obo:CHEBI_25944 , obo:CHEBI_33286 . obo:CHEBI_33856 a rdfs:Class ; rdfs:label "aromatic amino acid" ; rdfs:comment "An amino acid whose structure includes an aromatic ring." ; rdfs:subClassOf obo:CHEBI_33659 , obo:CHEBI_33709 . obo:CIDO_0020238 a rdfs:Class ; rdfs:label "PMSF-INNO SARS-CoV-2 RT-PCR Test" ; rdfs:seeAlso ; rdfs:subClassOf obo:CIDO_0000454 . obo:PR_P04626 a rdfs:Class ; rdfs:label "receptor tyrosine-protein kinase erbB-2 (human)" ; rdfs:comment "A receptor tyrosine-protein kinase erbB-2 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000002082 , obo:PR_000029067 . obo:OPMI_0000584 a rdfs:Class ; rdfs:label "payer plan temporal region"@en ; rdfs:comment "A temporal region that is associated with the payment process defined in a payer plan" ; rdfs:subClassOf obo:BFO_0000008 . obo:PR_000007342 a rdfs:Class ; rdfs:label "fatty acyl-CoA reductase 2" ; rdfs:comment "A protein that is a translation product of the human FAR2 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:NCBITaxon_1117225 a rdfs:Class ; rdfs:label "Bat coronavirus 2231/Philippines/2010" ; rdfs:subClassOf obo:NCBITaxon_366617 . obo:NCBITaxon_871683 a rdfs:Class ; rdfs:label "Feline coronavirus UU34" ; rdfs:subClassOf obo:NCBITaxon_12663 . obo:CIDO_0000077 a rdfs:Class ; rdfs:label "chemical role against SARS-CoV-2 entry"@en ; rdfs:subClassOf obo:CIDO_0000076 . obo:CIDO_0020046 a rdfs:Class ; rdfs:label "BinaxNOWTM COVID-19 Ag Card Home Test" ; rdfs:seeAlso ; rdfs:subClassOf obo:CIDO_0000454 . obo:CIDO_0020028 a rdfs:Class ; rdfs:label "AQ-TOP COVID-19 Rapid Detection Kit" ; rdfs:seeAlso ; rdfs:subClassOf obo:CIDO_0000454 . obo:PR_O00187 a rdfs:Class ; rdfs:label "mannan-binding lectin serine protease 2 (human)" ; rdfs:comment "A mannan-binding lectin serine protease 2 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000010194 , obo:PR_000029067 . obo:NCBITaxon_2591229 a rdfs:Class ; rdfs:label "Coronavirus BtSk-AlphaCoV/GX2018B" ; rdfs:subClassOf obo:NCBITaxon_2691591 . obo:CIDO_0001126 a rdfs:Class ; rdfs:label "SARS-CoV2 orf8 protein binding to human PCSK6"@en ; rdfs:comment "SARS-CoV2 orf8 protein binding to human PCSK6, as evidented by an affinity-purification mass spectrometry experiment" ; rdfs:subClassOf obo:CIDO_0000051 . obo:PR_000011129 a rdfs:Class ; rdfs:label "serine/threonine-protein kinase Nek3" ; rdfs:comment "A protein that is a translation product of the human NEK3 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:CHEBI_24650 a rdfs:Class ; rdfs:label "hydroxamic acid" ; rdfs:comment "A compound, RkE(=O)lNHOH, derived from an oxoacid RkE(=O)l(OH) (l =/= 0) by replacing -OH with -NHOH, and derivatives thereof. Specific examples of hydroxamic acids are preferably named as N-hydroxy amides." ; rdfs:subClassOf obo:CHEBI_37622 . obo:NCBITaxon_1503295 a rdfs:Class ; rdfs:label "BtPa-BetaCoV/GD2013" ; rdfs:subClassOf obo:NCBITaxon_694008 . obo:BFO_0000020 a rdfs:Class ; rdfs:label "specifically dependent continuant"@en ; rdfs:comment "A continuant that inheres in or is borne by other entities. Every instance of A requires some specific instance of B which must always be the same."@en ; rdfs:subClassOf obo:BFO_0000002 . obo:VO_0005119 a rdfs:Class ; rdfs:label "MERS England1 S DNA + England1 S protein subunit vaccine" ; rdfs:comment "A MERS combination vaccine made of made of the VRC8400 plasmid that encodes the full-length, membrane anchore MERS spike protein and a DNA vaccine that is a plasmid that encoded S1 subunit" ; rdfs:subClassOf obo:VO_0004900 . obo:NCBITaxon_669512 a rdfs:Class ; rdfs:label "Bat coronavirus SLO1A0050/2008/SVN" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:GO_0048146 a rdfs:Class ; rdfs:label "positive regulation of fibroblast proliferation" ; rdfs:comment "Any process that activates or increases the frequency, rate or extent of multiplication or reproduction of fibroblast cells." ; rdfs:subClassOf obo:GO_0008284 , obo:GO_0042127 . obo:CHEBI_61313 a rdfs:Class ; rdfs:label "C21-steroid" ; rdfs:comment "A steroid that has a structure based on a 21-carbon (pregnane) skeleton. Note that individual examples may have ring substituents at other positions and/or contain double bonds, aromatic A-rings, expanded/contracted rings etc., so the formula and mass may vary from that given for the generic structure." ; rdfs:subClassOf obo:CHEBI_35341 . obo:CHEBI_24067 a rdfs:Class ; rdfs:label "fluoroalkane" ; rdfs:comment "A haloalkane that is an alkane in which at least one hydrogen atom has been replaced by a fluorine atom." ; rdfs:subClassOf obo:CHEBI_24469 , obo:CHEBI_37143 . a rdfs:Class ; rdfs:label "CICLESONIDE" ; rdfs:subClassOf . obo:CHEBI_36339 a rdfs:Class ; rdfs:label "baryon" ; rdfs:comment "Baryon is a fermion that does experience the strong force (strong interaction). The term is derived from the Greek betaalpharhoupsilonsigma (heavy)." ; rdfs:subClassOf obo:CHEBI_36340 , obo:CHEBI_36344 . obo:CIDO_0000678 a rdfs:Class ; rdfs:label "L981F in SARS-CoV-2 S protein" ; rdfs:comment "An AA mutation or AA variant that has mutated an amino acid at position 981 into a phenylalanine in S protein." ; rdfs:subClassOf obo:CIDO_0001161 . obo:NCBITaxon_1643899 a rdfs:Class ; rdfs:label "Bat coronavirus BEM073F" ; rdfs:subClassOf obo:NCBITaxon_696098 . a rdfs:Class ; rdfs:label "Otitis [Disease/Finding]" ; rdfs:subClassOf . obo:PR_000004929 a rdfs:Class ; rdfs:label "atypical kinase COQ8A, mitochondrial" ; rdfs:comment "A protein that is a translation product of the human COQ8A gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:CIDO_0000058 a rdfs:Class ; rdfs:label "SARS-CoV-2 Nsp13 protein interaction with host protein"@en ; rdfs:comment "A molecular interaction that has participant of the SARS-CoV-2 Nsp13 protein and a host protein" ; rdfs:subClassOf obo:CIDO_0000348 . obo:CHEBI_33560 a rdfs:Class ; rdfs:label "p-block element atom" ; rdfs:comment "Any main group element atom belonging to the p-block of the periodic table." ; rdfs:subClassOf obo:CHEBI_33318 . obo:NCBITaxon_33738 a rdfs:Class ; rdfs:label "Porcine transmissible gastroenteritis coronavirus strain Neb72-RT" ; rdfs:subClassOf obo:NCBITaxon_11149 . obo:GO_0072507 a rdfs:Class ; rdfs:label "divalent inorganic cation homeostasis" ; rdfs:comment "Any process involved in the maintenance of an internal steady state of divalent cations within an organism or cell." ; rdfs:subClassOf obo:GO_0055080 , obo:GO_0098771 . obo:HP_0000726 a rdfs:Class ; rdfs:label "Dementia" ; rdfs:comment "A loss of global cognitive ability of sufficient amount to interfere with normal social or occupational function. Dementia represents a loss of previously present cognitive abilities, generally in adults, and can affect memory, thinking, language, judgment, and behavior." ; rdfs:subClassOf obo:HP_0011446 . obo:PR_Q12809 a rdfs:Class ; rdfs:label "potassium voltage-gated channel subfamily H member 2 (human)" ; rdfs:comment "A voltage-gated potassium channel KCNH2 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000000791 , obo:PR_000029067 . obo:CHEBI_76761 a rdfs:Class ; rdfs:label "EC 3.2.* (glycosylase) inhibitor" ; rdfs:comment "A hydrolase inhibitor that interferes with the action of any glycosylase (EC 3.2.*.*)." ; rdfs:subClassOf obo:CHEBI_76759 . obo:UBERON_0002106 a rdfs:Class ; rdfs:label "spleen" ; rdfs:comment "the organ that functions to filter blood and to store red corpuscles and platelets" ; rdfs:subClassOf obo:UBERON_0000465 . obo:CHEBI_37838 a rdfs:Class ; rdfs:label "carboacyl group" ; rdfs:comment "A carboacyl group is a group formed by loss of at least one OH from the carboxy group of a carboxylic acid." ; rdfs:subClassOf obo:CHEBI_22221 . obo:CHEBI_38163 a rdfs:Class ; rdfs:label "organic heterotetracyclic compound" ; rdfs:subClassOf obo:CHEBI_38166 . obo:CHEBI_64915 a rdfs:Class ; rdfs:label "antiplasmodial drug" ; rdfs:comment "An antiparasitic drug which is effective against Apicomplexan parasites in the genus Plasmodium. The genus contains over 200 species and includes those responsible for malaria." ; rdfs:subClassOf obo:CHEBI_35442 , obo:CHEBI_35820 . a rdfs:Class ; rdfs:label "Enterocolitis, Pseudomembranous [Disease/Finding]" ; rdfs:subClassOf , . obo:NCBITaxon_1679884 a rdfs:Class ; rdfs:label "Coronavirus RCoV/D_RMU10_1087/Apo_fla/GER/2010" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:HP_0009830 a rdfs:Class ; rdfs:label "Peripheral neuropathy" ; rdfs:comment "Peripheral neuropathy is a general term for any disorder of the peripheral nervous system. The main clinical features used to classify peripheral neuropathy are distribution, type (mainly demyelinating versus mainly axonal), duration, and course." ; rdfs:subClassOf obo:HP_0012639 . obo:OBCS_0000121 a rdfs:Class ; rdfs:label "inferential statistical data analysis"@en ; rdfs:comment "A statistical data analysis that uses patterns in the sample data to draw inferences about the population represented, accounting for randomness." ; rdfs:subClassOf obo:OBCS_0000001 . obo:CIDO_0020132 a rdfs:Class ; rdfs:label "Ethos Laboratories SARS-CoV-2 MALDI-TOF Assay" ; rdfs:seeAlso ; rdfs:subClassOf obo:CIDO_0000454 . obo:CHEBI_37163 a rdfs:Class ; rdfs:label "glucan" ; rdfs:comment "A polysaccharide composed of glucose residues." ; rdfs:subClassOf obo:CHEBI_37164 . obo:PR_P61313 a rdfs:Class ; rdfs:label "60S ribosomal protein L15 (human)" ; rdfs:comment "A 60S ribosomal protein L15 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000014195 , obo:PR_000029067 . obo:CHEBI_23451 a rdfs:Class ; rdfs:label "cyclitol" ; rdfs:comment "A polyol consisting of a cycloalkane containing at least three hydroxy groups, each attached to a different ring carbon atom." ; rdfs:subClassOf obo:CHEBI_26191 . obo:PR_P16502 a rdfs:Class ; rdfs:subClassOf obo:PR_000000001 . obo:CHEBI_24127 a rdfs:Class ; rdfs:label "fungicide" ; rdfs:comment "A substance used to destroy fungal pests." ; rdfs:subClassOf obo:CHEBI_25944 , obo:CHEBI_35718 . obo:NCBITaxon_2801851 a rdfs:Class ; rdfs:label "Bat coronavirus RacCS203" ; rdfs:subClassOf obo:NCBITaxon_1986197 . obo:PR_P19784 a rdfs:Class ; rdfs:label "casein kinase II subunit alpha' (human)" ; rdfs:comment "A casein kinase II subunit alpha' that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000005951 , obo:PR_000029067 . obo:PR_000007535 a rdfs:Class ; rdfs:label "FK506-binding protein 15" ; rdfs:comment "A protein that is a translation product of the human FKBP15 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:PR_O75747 a rdfs:Class ; rdfs:label "phosphatidylinositol 3-kinase C2 domain-containing subunit gamma (human)" ; rdfs:comment "A phosphatidylinositol 3-kinase C2 domain-containing subunit gamma that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000012717 , obo:PR_000029067 . obo:NCBITaxon_1146854 a rdfs:Class ; rdfs:label "Bat coronavirus M.nattereri/UK/Sav/1091C" ; rdfs:subClassOf obo:NCBITaxon_366617 . obo:CHEBI_139588 a rdfs:Class ; rdfs:label "alpha-hydroxy ketone" ; rdfs:comment "An alpha-oxyketone that has a hydroxy group as the alpha-oxy moiety." ; rdfs:subClassOf obo:CHEBI_30879 , obo:CHEBI_52396 . obo:VO_0001743 a rdfs:Class ; rdfs:label "Canine Coronavirus Killed Virus Vaccine (USDA: 14P5.20)" ; rdfs:subClassOf obo:VO_0000932 . obo:PR_Q99470 a rdfs:Class ; rdfs:label "stromal cell-derived factor 2 (human)" ; rdfs:comment "A stromal cell-derived factor 2 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000014560 , obo:PR_000029067 . obo:CHEBI_16646 a rdfs:Class ; rdfs:label "carbohydrate" ; rdfs:comment "Any member of the class of organooxygen compounds that is a polyhydroxy-aldehyde or -ketone or a lactol resulting from their intramolecular condensation (monosaccharides); substances derived from these by reduction of the carbonyl group (alditols), by oxidation of one or more hydroxy groups to afford the corresponding aldehydes, ketones, or carboxylic acids, or by replacement of one or more hydroxy group(s) by a hydrogen atom; and polymeric products arising by intermolecular acetal formation between two or more such molecules (disaccharides, polysaccharides and oligosaccharides). Carbohydrates contain only carbon, hydrogen and oxygen atoms; prior to any oxidation or reduction, most have the empirical formula Cm(H2O)n. Compounds obtained from carbohydrates by substitution, etc., are known as carbohydrate derivatives and may contain other elements. Cyclitols are generally not regarded as carbohydrates." ; rdfs:subClassOf obo:CHEBI_78616 . obo:NCBITaxon_694008 a rdfs:Class ; rdfs:label "Pipistrellus bat coronavirus HKU5" ; rdfs:subClassOf obo:NCBITaxon_2509494 . obo:CHEBI_38032 a rdfs:Class ; rdfs:label "carbotricyclic compound" ; rdfs:comment "A carbopolyclic compound comprising of three carbocyclic rings." ; rdfs:subClassOf obo:CHEBI_35294 , obo:CHEBI_51959 . obo:PR_P78406 a rdfs:Class ; rdfs:label "mRNA export factor RAE1 (human)" ; rdfs:comment "An mRNA export factor RAE1 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000013685 , obo:PR_000029067 . obo:CIDO_0000566 a rdfs:Class ; rdfs:label "WFCANQSTSVYSANG" ; rdfs:comment "A coronavirus epitope that is part of some S protein from HCoV NL63 composed of the following amino acids WFCANQSTSVYSANG" ; rdfs:subClassOf obo:CIDO_0000449 . obo:GO_1903039 a rdfs:Class ; rdfs:label "positive regulation of leukocyte cell-cell adhesion" ; rdfs:comment "Any process that activates or increases the frequency, rate or extent of leukocyte cell-cell adhesion." ; rdfs:subClassOf obo:GO_0022407 , obo:GO_0022409 . obo:GO_0007193 a rdfs:Class ; rdfs:label "adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway" ; rdfs:comment "A G protein-coupled receptor signaling pathway in which the signal is transmitted via the inhibition of adenylyl cyclase activity and a subsequent decrease in the intracellular concentration of cyclic AMP (cAMP)." ; rdfs:subClassOf obo:GO_0007188 . obo:CHEBI_38485 a rdfs:Class ; rdfs:label "indolizines" ; rdfs:subClassOf obo:CHEBI_27171 , obo:CHEBI_38101 . obo:NCBITaxon_1897073 a rdfs:Class ; rdfs:label "Bat coronavirus Eum.gla/242/BRA/2013" ; rdfs:subClassOf obo:NCBITaxon_696098 . obo:CIDO_0000237 a rdfs:Class ; rdfs:label "AA variant in SARS-CoV-2"@en ; rdfs:comment "An AA variant that occurs in a SARS-CoV-2 viral proteome" ; rdfs:subClassOf obo:CIDO_0000243 . obo:CHEBI_33551 a rdfs:Class ; rdfs:label "organosulfonic acid" ; rdfs:comment "An organic derivative of sulfonic acid in which the sulfo group is linked directly to carbon." ; rdfs:subClassOf obo:CHEBI_33261 , obo:CHEBI_33552 , obo:CHEBI_64709 . a rdfs:Class ; rdfs:label "Hormones, Hormone Substitutes, and Hormone Antagonists [Chemical/Ingredient]" ; rdfs:subClassOf . obo:HP_0010574 a rdfs:Class ; rdfs:label "Abnormality of the epiphysis of the femoral head" ; rdfs:comment "Any abnormality of the proximal epiphysis of the femur." ; rdfs:subClassOf obo:HP_0002823 , obo:HP_0006499 . obo:IAO_0000578 a rdfs:Class ; rdfs:label "centrally registered identifier"@en ; rdfs:comment "An information content entity that consists of a CRID symbol and additional information about which CRID registry it belongs. "@en ; rdfs:subClassOf obo:IAO_0000030 . obo:CHEBI_36856 a rdfs:Class ; rdfs:label "hydrogen isocyanide" ; rdfs:subClassOf obo:CHEBI_33405 . obo:CHEBI_38777 a rdfs:Class ; rdfs:label "azetidines" ; rdfs:subClassOf obo:CHEBI_25693 , obo:CHEBI_38101 . obo:VO_0005199 a rdfs:Class ; rdfs:label "COVID-19 recombinant vector vaccine"@en ; rdfs:subClassOf obo:VO_0000484 , obo:VO_0004908 . obo:CIDO_0020291 a rdfs:Class ; rdfs:label "Sienna-Clarity COVIBLOCK COVID-19 IgG/IgM Rapid Test Cassette" ; rdfs:seeAlso ; rdfs:subClassOf obo:CIDO_0000454 . obo:CIDO_0000317 a rdfs:Class ; rdfs:label "CTFEYVSQPFLMDLE"@en ; rdfs:subClassOf obo:CIDO_0000314 . obo:PR_O95977 a rdfs:Class ; rdfs:label "sphingosine 1-phosphate receptor 4 (human)" ; rdfs:comment "A sphingosine 1-phosphate receptor 4 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000001709 , obo:PR_000029067 . obo:GO_0044057 a rdfs:Class ; rdfs:label "regulation of system process" ; rdfs:comment "Any process that modulates the frequency, rate or extent of a system process, a multicellular organismal process carried out by any of the organs or tissues in an organ system." ; rdfs:subClassOf obo:GO_0051239 . obo:PR_P35462 a rdfs:Class ; rdfs:label "D(3) dopamine receptor (human)" ; rdfs:comment "A D(3) dopamine receptor that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000001178 , obo:PR_000029067 . a rdfs:Class ; rdfs:label "RIMANTADINE" ; rdfs:subClassOf . obo:CHEBI_33904 a rdfs:Class ; rdfs:label "molluscicide" ; rdfs:comment "A substance used to destroy pests of the phylum Mollusca." ; rdfs:subClassOf obo:CHEBI_25944 . obo:CHEBI_38523 a rdfs:Class ; rdfs:label "benzazepine alkaloid" ; rdfs:subClassOf obo:CHEBI_22315 , obo:CHEBI_35676 . obo:CHEBI_110725 a rdfs:Class ; rdfs:label "EC 2.1.1.8 (histamine N-methyltransferase) inhibitor" ; rdfs:comment "An EC 2.1.1.* (methyltransferases) inhibitor that interferes with the action of histamine N-methyltransferase (EC 2.1.1.8)." ; rdfs:subClassOf obo:CHEBI_76871 . obo:NCBITaxon_1034322 a rdfs:Class ; rdfs:label "Rm-Bat-CoV 09-07/2009/MV" ; rdfs:subClassOf obo:NCBITaxon_366617 . a rdfs:Class ; rdfs:label "Aza Compounds [Chemical/Ingredient]" ; rdfs:subClassOf . obo:NCBITaxon_497948 a rdfs:Class ; rdfs:label "Bat coronavirus M.dau/Germany/D8.45/2007" ; rdfs:subClassOf obo:NCBITaxon_366617 . obo:CHEBI_83056 a rdfs:Class ; rdfs:label "Daphnia magna metabolite" ; rdfs:comment "A Daphnia metabolite produced by the species Daphnia magna." ; rdfs:subClassOf obo:CHEBI_83057 . obo:DOID_0080831 a rdfs:Class ; rdfs:label "subjective cognitive decline"@en ; rdfs:comment "A cognitive disorder that is characterized by the presence of significant and persistent cognitive complaints." ; rdfs:subClassOf obo:DOID_1561 . obo:CHEBI_91450 a rdfs:Class ; rdfs:label "5-(4-amino-1-propan-2-yl-3-pyrazolo[3,4-d]pyrimidinyl)-1,3-benzoxazol-2-amine" ; rdfs:subClassOf obo:CHEBI_46700 . obo:CIDO_0000898 a rdfs:Class ; rdfs:label "SARS-CoV2 nsp7 protein binding to human FAM162A" ; rdfs:comment "SARS-CoV2 nsp7 protein binding to human FAM162A, as evidented by an affinity-purification mass spectrometry experiment" ; rdfs:subClassOf obo:CIDO_0000049 . obo:PR_Q9BQT8 a rdfs:Class ; rdfs:label "mitochondrial 2-oxodicarboxylate carrier (human)" ; rdfs:comment "A mitochondrial 2-oxodicarboxylate carrier that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000015017 , obo:PR_000029067 . obo:CIDO_0000958 a rdfs:Class ; rdfs:label "SARS-CoV2 nsp9 protein binding to human NUP58" ; rdfs:comment "SARS-CoV2 nsp9 protein binding to human NUP58, as evidented by an affinity-purification mass spectrometry experiment" ; rdfs:subClassOf obo:CIDO_0000583 . obo:NCBITaxon_2042576 a rdfs:Class ; rdfs:label "Coronavirus PREDICT CoV-52" ; rdfs:subClassOf obo:NCBITaxon_366617 . obo:PR_P11310 a rdfs:Class ; rdfs:label "medium-chain specific acyl-CoA dehydrogenase, mitochondrial (human)" ; rdfs:comment "A medium-chain specific acyl-CoA dehydrogenase, mitochondrial that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000003601 , obo:PR_000029067 . obo:NCBITaxon_353145 a rdfs:Class ; rdfs:label "SARS coronavirus ZJ02" ; rdfs:subClassOf obo:NCBITaxon_694009 . a rdfs:Class ; rdfs:label "Route of Excretion [PK]" ; rdfs:subClassOf . obo:NCBITaxon_1679874 a rdfs:Class ; rdfs:label "Coronavirus Hare_CoV/La06_378/Lep_gra/ESP/2006" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:GO_0019439 a rdfs:Class ; rdfs:label "aromatic compound catabolic process" ; rdfs:comment "The chemical reactions and pathways resulting in the breakdown of aromatic compounds, any substance containing an aromatic carbon ring." ; rdfs:subClassOf obo:GO_0006725 , obo:GO_0044248 . obo:CHEBI_146270 a rdfs:Class ; rdfs:label "oneirogen" ; rdfs:comment "Any substance that produces or enhances dream-like states of consciousness." ; rdfs:subClassOf obo:CHEBI_35471 . obo:NCBITaxon_293933 a rdfs:Class ; rdfs:label "SARS coronavirus GZ0402" ; rdfs:subClassOf obo:NCBITaxon_694009 . obo:GO_0050708 a rdfs:Class ; rdfs:label "regulation of protein secretion" ; rdfs:comment "Any process that modulates the frequency, rate or extent of the controlled release of a protein from a cell." ; rdfs:subClassOf obo:GO_0051223 , obo:GO_1903530 . obo:UBERON_0000481 a rdfs:Class ; rdfs:label "multi-tissue structure" ; rdfs:comment "Anatomical structure that has as its parts two or more portions of tissue of at least two different types and which through specific morphogenetic processes forms a single distinct structural unit demarcated by bona-fide boundaries from other distinct structural units of different types." ; rdfs:subClassOf obo:UBERON_0000465 . obo:DRON_00016014 a rdfs:Class ; rdfs:label "Triflupromazine" ; rdfs:subClassOf obo:OBI_0000047 . obo:PR_Q6NXT4 a rdfs:Class ; rdfs:label "zinc transporter 6 (human)" ; rdfs:comment "A zinc transporter 6 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000015079 , obo:PR_000029067 . obo:OPMI_0000555 a rdfs:Class ; rdfs:label "primary discarge diagnosis status"@en ; rdfs:subClassOf obo:OPMI_0000526 . obo:DOID_0080600 a rdfs:Class ; rdfs:label "COVID-19"@en ; rdfs:comment "A Coronavirus infection that is characterized by fever, cough and shortness of breath and that has_material_basis_in SARS-CoV-2." ; rdfs:subClassOf obo:DOID_0080599 . obo:PR_000013058 a rdfs:Class ; rdfs:label "peroxisome proliferator-activated receptor gamma" ; rdfs:comment "A protein that is a translation product of the human PPARG gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:GO_0000165 a rdfs:Class ; rdfs:label "MAPK cascade" ; rdfs:comment "An intracellular protein kinase cascade containing at least a MAPK, a MAPKK and a MAP3K. The cascade can also contain an additional tiers: the upstream MAP4K. The kinases in each tier phosphorylate and activate the kinase in the downstream tier to transmit a signal within a cell." ; rdfs:subClassOf obo:GO_0035556 . obo:GO_0015872 a rdfs:Class ; rdfs:label "dopamine transport" ; rdfs:comment "The directed movement of dopamine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Dopamine is a catecholamine neurotransmitter and a metabolic precursor of noradrenaline and adrenaline." ; rdfs:subClassOf obo:GO_0006812 , obo:GO_0051937 . obo:GO_0019079 a rdfs:Class ; rdfs:label "viral genome replication" ; rdfs:comment "Any process involved directly in viral genome replication, including viral nucleotide metabolism." ; rdfs:subClassOf obo:GO_0016032 . obo:CHEBI_64767 a rdfs:Class ; rdfs:label "anionic group" ; rdfs:comment "A group that carries an overall negative charge." ; rdfs:subClassOf obo:CHEBI_24433 . obo:HP_0011716 a rdfs:Class ; rdfs:label "Junctional ectopic tachycardia" ; rdfs:comment "Junctional ectopic tachycardia (JET) is a unique type of supraventricular arrhythmia defined by narrow QRS complex and atrioventricular (AV) dissociation or retrograde atrial conduction in a 1:1 pattern." ; rdfs:subClassOf obo:HP_0011687 . obo:PR_000007805 a rdfs:Class ; rdfs:label "cyclin-G-associated kinase" ; rdfs:comment "A protein that is a translation product of the human GAK gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:CIDO_0000094 a rdfs:Class ; rdfs:label "MERS-CoV replication inside cell"@en ; rdfs:comment "A coronavirus-host interaction by which the MERS-CoV virus replicates inside the host cell" ; rdfs:subClassOf obo:CIDO_0000086 . obo:PR_P35368 a rdfs:Class ; rdfs:label "alpha-1B adrenergic receptor (human)" ; rdfs:comment "An alpha-1B adrenergic receptor that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000001184 , obo:PR_000029067 . a rdfs:Class ; rdfs:label "Neoplasms [Disease/Finding]" ; rdfs:subClassOf . obo:CHEBI_15904 a rdfs:Class ; rdfs:label "long-chain fatty acid" ; rdfs:comment "A fatty acid with a chain length ranging from C13 to C22." ; rdfs:subClassOf obo:CHEBI_35366 . obo:OGG_1000002759 a rdfs:Class ; rdfs:label "genome of Eukaryota" ; rdfs:comment "The genome of an organism of Eukaryota" ; rdfs:subClassOf obo:OGG_0000000001 . obo:CHEBI_76738 a rdfs:Class ; rdfs:label "EC 1.11.* (oxidoreductase acting on peroxide as donors) inhibitor" ; rdfs:comment "An oxidoreductase inhibitor which interferes with the action of an oxidoreductase acting on peroxide as donors (EC 1.11.*.*)." ; rdfs:subClassOf obo:CHEBI_76725 . obo:PR_000001615 a rdfs:Class ; rdfs:label "muscarinic acetylcholine receptor M3" ; rdfs:comment "A muscarinic acetylcholine receptor that is a translation product of the human CHRM3 gene or a 1:1 ortholog thereof. This receptor is expressed in many glands, in lungs, and in the smooth muscles of blood vessels." ; rdfs:subClassOf obo:PR_000001488 . obo:CIDO_0000858 a rdfs:Class ; rdfs:label "SARS-CoV2 nsp13 protein binding to human TBKBP1" ; rdfs:comment "SARS-CoV2 nsp13 protein binding to human TBKBP1, as evidented by an affinity-purification mass spectrometry experiment" ; rdfs:subClassOf obo:CIDO_0000058 . obo:PR_O14936 a rdfs:Class ; rdfs:label "peripheral plasma membrane protein CASK (human)" ; rdfs:comment "A peripheral plasma membrane protein CASK that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000005051 , obo:PR_000029067 . obo:CHEBI_33459 a rdfs:Class ; rdfs:label "pnictogen oxoanion" ; rdfs:subClassOf obo:CHEBI_33302 , obo:CHEBI_35406 . obo:NCBITaxon_497951 a rdfs:Class ; rdfs:label "Bat coronavirus M.dau/Germany/D8.32/2007" ; rdfs:subClassOf obo:NCBITaxon_366617 . obo:NCBITaxon_9612 a rdfs:Class ; rdfs:label "Canis lupus" ; rdfs:subClassOf obo:NCBITaxon_9611 . obo:CHEBI_25017 a rdfs:Class ; rdfs:label "leucine" ; rdfs:comment "A branched-chain amino acid that consists of glycine in which one of the hydrogens attached to the alpha-carbon is substituted by an isobutyl group." ; rdfs:subClassOf obo:CHEBI_22918 , obo:CHEBI_33704 . obo:NCBITaxon_33733 a rdfs:Class ; rdfs:label "Feline enteric coronavirus (strain 79-1683)" ; rdfs:subClassOf obo:NCBITaxon_12663 . obo:CIDO_0000845 a rdfs:Class ; rdfs:label "SARS-CoV2 nsp13 protein binding to human HOOK1" ; rdfs:comment "SARS-CoV2 nsp13 protein binding to human HOOK1, as evidented by an affinity-purification mass spectrometry experiment" ; rdfs:subClassOf obo:CIDO_0000058 . obo:GO_0042221 a rdfs:Class ; rdfs:label "response to chemical" ; rdfs:comment "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chemical stimulus." ; rdfs:subClassOf obo:GO_0050896 . obo:DOID_3312 a rdfs:Class ; rdfs:label "bipolar disorder" ; rdfs:comment "A mood disorder that involves alternating periods of mania and depression." ; rdfs:subClassOf obo:DOID_3324 . obo:CIDO_0020273 a rdfs:Class ; rdfs:label "SARS-CoV-2 MassArray Test" ; rdfs:seeAlso ; rdfs:subClassOf obo:CIDO_0000454 . obo:NCBITaxon_745741 a rdfs:Class ; rdfs:label "Coronavirus P.pipi/VM314/2008/NLD" ; rdfs:subClassOf obo:NCBITaxon_696098 . obo:CIDO_0000739 a rdfs:Class ; rdfs:label "L452Q in SARS-CoV-2 S protein"@en ; rdfs:comment "An AA mutation or AA variant that has mutated an amino acid at position 452 into glutamine in S protein." ; rdfs:subClassOf obo:CIDO_0000593 . obo:CHEBI_32065 a rdfs:Class ; rdfs:label "Proscillaridin" ; rdfs:subClassOf obo:CHEBI_50860 . obo:OPMI_0000509 a rdfs:Class ; rdfs:label "procedure start datetime"@en ; rdfs:comment "The date and time when a procedure starts" ; rdfs:subClassOf obo:OPMI_0000507 . obo:CIDO_0000802 a rdfs:Class ; rdfs:label "SARS-CoV2 nsp11 protein binding to human TBCA" ; rdfs:comment "SARS-CoV2 nsp11 protein binding to human TBCA, as evidented by an affinity-purification mass spectrometry experiment" ; rdfs:subClassOf obo:CIDO_0000070 . obo:OBI_1110041 a rdfs:Class ; rdfs:label "lymph node cell specimen"@en ; rdfs:comment "A cell specimen comprised of a mixed population of cells obtained by processing whole lymph node into individual cells, typically performed using a sieve. This population includes T cells, B cells, macrophages, and other cell types." ; rdfs:subClassOf obo:OBI_0000953 , obo:OBI_0001468 . a rdfs:Class ; rdfs:label "Decreased Prostaglandin Activity [PE]" ; rdfs:subClassOf . obo:PR_000001356 a rdfs:Class ; rdfs:label "immunoglobulin gamma Fc receptor I" ; rdfs:comment "A protein with a core domain architecture consisting of an extracellular domain containing two or three copies of the Immunoglobulin domain (Pfam:PF00047), followed by a single-pass transmembrane region and a small intracellular domain." ; rdfs:subClassOf obo:PR_000000001 . a rdfs:Class ; rdfs:label "CETYLPYRIDINIUM" ; rdfs:subClassOf . obo:GO_0043086 a rdfs:Class ; rdfs:label "negative regulation of catalytic activity" ; rdfs:comment "Any process that stops or reduces the activity of an enzyme." ; rdfs:subClassOf obo:GO_0050790 , obo:GO_0065009 . obo:NCBITaxon_1076428 a rdfs:Class ; rdfs:label "Betacoronavirus E.isa/M/Spain/2007" ; rdfs:subClassOf obo:NCBITaxon_696098 . obo:CHEBI_28179 a rdfs:Class ; rdfs:label "benzamide" ; rdfs:comment "An aromatic amide that consists of benzene bearing a single carboxamido substituent. The parent of the class of benzamides." ; rdfs:subClassOf obo:CHEBI_22702 . obo:NCBITaxon_389255 a rdfs:Class ; rdfs:label "Bat coronavirus A527/2005" ; rdfs:subClassOf obo:NCBITaxon_366617 . obo:HP_0002018 a rdfs:Class ; rdfs:label "Nausea" ; rdfs:comment "A sensation of unease in the stomach together with an urge to vomit." ; rdfs:subClassOf obo:HP_0002017 . obo:CIDO_0001071 a rdfs:Class ; rdfs:label "SARS-CoV2 Spike protein binding to human ZDHHC5" ; rdfs:comment "SARS-CoV2 Spike protein binding to human ZDHHC5, as evidented by an affinity-purification mass spectrometry experiment" ; rdfs:subClassOf obo:CIDO_0000060 . obo:HP_0006682 a rdfs:Class ; rdfs:label "Ventricular extrasystoles" ; rdfs:comment "Premature ventricular contractions (PVC) or ventricular extrasystoles are premature contractions of the heart that arise in response to an impulse in the ventricles rather than the normal impulse from the sinoatrial (SA) node." ; rdfs:subClassOf obo:HP_0004308 . obo:CHEBI_77022 a rdfs:Class ; rdfs:label "EC 2.3.3.* (acyltransferase converting acyl to alkyl group on transfer) inhibitor" ; rdfs:comment "An EC 2.3.* (acyltransferase) inhibitor that interferes with the action of an acyltransferase which converts the acyl group to an alkyl group on transfer (EC 2.3.3.*)." ; rdfs:subClassOf obo:CHEBI_76661 . obo:OPMI_0000577 a rdfs:Class ; rdfs:label "observation period start date"@en ; rdfs:comment "A date when an observation starts." ; rdfs:subClassOf obo:BFO_0000148 , obo:OPMI_0000576 . a rdfs:Class ; rdfs:label "Benzhydryl Compounds [Chemical/Ingredient]" ; rdfs:subClassOf . obo:DOID_1307 a rdfs:Class ; rdfs:label "dementia" ; rdfs:comment "A cognitive disorder resulting from a loss of brain function affecting memory, thinking, language, judgement and behavior." ; rdfs:subClassOf obo:DOID_1561 . obo:PR_P21453 a rdfs:Class ; rdfs:label "sphingosine 1-phosphate receptor 1 (human)" ; rdfs:comment "A sphingosine 1-phosphate receptor 1 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000001706 , obo:PR_000029067 . obo:NCBITaxon_389164 a rdfs:Class ; rdfs:label "Bat coronavirus (BtCoV/A970/2005)" ; rdfs:subClassOf obo:NCBITaxon_389126 . obo:CHEBI_29133 a rdfs:Class ; rdfs:label "dextrorphan" ; rdfs:subClassOf obo:CHEBI_25418 . obo:GO_0006874 a rdfs:Class ; rdfs:label "cellular calcium ion homeostasis" ; rdfs:comment "Any process involved in the maintenance of an internal steady state of calcium ions at the level of a cell." ; rdfs:subClassOf obo:GO_0006875 , obo:GO_0055074 , obo:GO_0072503 . obo:NCBITaxon_2078577 a rdfs:Class ; rdfs:label "Houbara coronavirus UAE-HKU28" ; rdfs:subClassOf obo:NCBITaxon_2724161 . obo:CIDO_0000075 a rdfs:Class ; rdfs:label "chemical role against SARS-CoV replication"@en ; rdfs:subClassOf obo:CIDO_0000072 . obo:NCBITaxon_1913643 a rdfs:Class ; rdfs:label "Bat coronavirus CDPHE15" ; rdfs:subClassOf obo:NCBITaxon_2509477 . obo:PR_000003271 a rdfs:Class ; rdfs:label "cyclin-dependent kinase 1" ; rdfs:comment "A CDK2-related kinase that is a translation product of the human CDK1 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000003270 . obo:PR_000009673 a rdfs:Class ; rdfs:label "La-related protein 7" ; rdfs:comment "A protein that is a translation product of the human LARP7 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:PR_000002341 a rdfs:Class ; rdfs:label "protein kinase C delta type" ; rdfs:comment "A protein kinase C, delta-like that is a translation product of the human PRKCD gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000002210 . obo:PR_P51681 a rdfs:Class ; rdfs:label "C-C chemokine receptor type 5 (human)" ; rdfs:comment "A C-C chemokine receptor type 5 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000001201 , obo:PR_000029067 . obo:PR_000015186 a rdfs:Class ; rdfs:label "sodium-dependent noradrenaline transporter" ; rdfs:comment "A protein that is a translation product of the human SLC6A2 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:PR_000004876 a rdfs:Class ; rdfs:label "complement C1q subcomponent subunit B" ; rdfs:comment "A protein that is a translation product of the human C1QB gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:NCBITaxon_2759 a rdfs:Class ; rdfs:label "Eukaryota" ; rdfs:subClassOf obo:BFO_0000040 , obo:OBI_0100026 . obo:CHEBI_32870 a rdfs:Class ; rdfs:label "D-prolino group" ; rdfs:subClassOf obo:CHEBI_32873 . obo:NCBITaxon_497937 a rdfs:Class ; rdfs:label "Bat coronavirus M.das/Germany/D5.17/2007" ; rdfs:subClassOf obo:NCBITaxon_366617 . obo:PR_P02746 a rdfs:Class ; rdfs:label "complement C1q subcomponent subunit B (human)" ; rdfs:comment "A complement C1q subcomponent subunit B that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000004876 , obo:PR_000029067 . obo:CHEBI_48545 a rdfs:Class ; rdfs:label "pentapeptide" ; rdfs:comment "Any molecule that contains five amino-acid residues connected by peptide linkages." ; rdfs:subClassOf obo:CHEBI_25676 . obo:NCBITaxon_903572 a rdfs:Class ; rdfs:label "Kenya bat coronavirus BtKY104" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:GO_0071702 a rdfs:Class ; rdfs:label "organic substance transport" ; rdfs:comment "The directed movement of organic substances into, out of or within a cell, or between cells, or within a multicellular organism by means of some agent such as a transporter or pore. An organic substance is a molecular entity that contains carbon." ; rdfs:subClassOf obo:GO_0006810 . obo:PR_000050289 a rdfs:Class ; rdfs:label "NSP2-3 intermediate (SARS-CoV-2)" ; rdfs:comment "A rep gene proteolytic cleavage product (SARS-CoV-2) that is the central portion produced by the enzymatic action of PL-PRO proteinase (nsp3) when it cleaves the precursor rep gene translation product (SARS-CoV-2) between residues 180-181 and 2763-2764." ; rdfs:subClassOf obo:PR_000050281 . obo:PR_O76024 a rdfs:Class ; rdfs:label "wolframin (human)" ; rdfs:comment "A wolframin that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000017414 , obo:PR_000029067 . obo:CHEBI_131604 a rdfs:Class ; rdfs:label "Mycoplasma genitalium metabolite" ; rdfs:comment "Any bacterial metabolite produced during a metabolic reaction in Mycoplasma genitalium." ; rdfs:subClassOf obo:CHEBI_76969 . obo:CHEBI_35443 a rdfs:Class ; rdfs:label "anthelminthic drug" ; rdfs:comment "Substance intended to kill parasitic worms (helminths)." ; rdfs:subClassOf obo:CHEBI_35442 . obo:CIDO_0000779 a rdfs:Class ; rdfs:label "SARS-CoV2 N protein binding to human FAM98A" ; rdfs:comment "SARS-CoV2 N protein binding to human FAM98A, as evidented by an affinity-purification mass spectrometry experiment" ; rdfs:subClassOf obo:CIDO_0000056 . obo:CIDO_0000407 a rdfs:Class ; rdfs:label "SARS-CoV-2 based on WHO classification"@en ; rdfs:subClassOf obo:NCBITaxon_2697049 . obo:PR_000008095 a rdfs:Class ; rdfs:label "guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1" ; rdfs:comment "A protein that is a translation product of the human GNB1 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:OBI_0002526 a rdfs:Class ; rdfs:label "skin of body specimen" ; rdfs:comment "A specimen that is derived from skin." ; rdfs:subClassOf obo:OBI_0001479 . obo:NCBITaxon_2794357 a rdfs:Class ; rdfs:label "Apodemus peninsulae coronavirus" ; rdfs:subClassOf obo:NCBITaxon_696098 . obo:CHEBI_168396 a rdfs:Class ; rdfs:label "mycophenolic acid" ; rdfs:comment "A member of the class of 2-benzofurans that is 2-benzofuran-1(3H)-one which is substituted at positions 4, 5, 6, and 7 by methyl, methoxy, (2E)-5-carboxy-3-methylpent-2-en-1-yl, and hydroxy groups, respectively. It is an antibiotic produced by Penicillium brevi-compactum, P. stoloniferum, P. echinulatum and related species. An immunosuppressant, it is widely used (partiularly as its sodium salt and as the 2-(morpholin-4-yl)ethyl ester prodrug, mycophenolate mofetil) to prevent tissue rejection following organ transplants and for the treatment of certain autoimmune diseases." ; rdfs:subClassOf obo:CHEBI_25384 , obo:CHEBI_33853 , obo:CHEBI_37581 , obo:CHEBI_38831 . obo:PATO_0001548 a rdfs:Class ; rdfs:label "quality of a liquid" ; rdfs:comment "A physical quality inhering in an entity exhibiting the physical characteristics of an amorphous (non-crystalline) form of matter between a gas and a solid that has a definite volume, but no definite shape." ; rdfs:subClassOf obo:PATO_0002198 . obo:NCBITaxon_749419 a rdfs:Class ; rdfs:label "Black-headed gull coronavirus CIR-66152" ; rdfs:subClassOf obo:NCBITaxon_749416 . obo:CHEBI_67016 a rdfs:Class ; rdfs:label "tetrahydrofolate" ; rdfs:comment "A folate obtained by deprotonation of any tetrahydrofolic acid." ; rdfs:subClassOf obo:CHEBI_67011 . obo:GO_0033365 a rdfs:Class ; rdfs:label "protein localization to organelle" ; rdfs:comment "A process in which a protein is transported to, or maintained in, a location within an organelle." ; rdfs:subClassOf obo:GO_0034613 . obo:CHEBI_24780 a rdfs:Class ; rdfs:label "imidazoles" ; rdfs:comment "A five-membered organic heterocycle containing two nitrogen atoms at positions 1 and 3, or any of its derivatives; compounds containing an imidazole skeleton." ; rdfs:subClassOf obo:CHEBI_23677 . obo:NCBITaxon_1472721 a rdfs:Class ; rdfs:label "Alphacoronavirus 2" ; rdfs:subClassOf obo:NCBITaxon_366617 . a rdfs:Class ; rdfs:label "Lactation [Disease/Finding]" ; rdfs:subClassOf . obo:CIDO_0001029 a rdfs:Class ; rdfs:label "AT-527" ; rdfs:subClassOf obo:CHEBI_23367 . obo:PR_P00519 a rdfs:Class ; rdfs:label "tyrosine-protein kinase ABL1 (human)" ; rdfs:comment "A tyrosine-protein kinase ABL1 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000003582 , obo:PR_000029067 . obo:CHEBI_60809 a rdfs:Class ; rdfs:label "adjuvant" ; rdfs:comment "Any pharmacological or immunological agent that modifies the effect of other agents such as drugs or vaccines while having few if any direct effects when given by itself." ; rdfs:subClassOf obo:CHEBI_52217 . obo:PR_000011533 a rdfs:Class ; rdfs:label "nuclear transport factor 2" ; rdfs:comment "A protein that is a translation product of the human NUTF2 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:NCBITaxon_903587 a rdfs:Class ; rdfs:label "Kenya bat coronavirus BtKY49" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:NCBITaxon_9605 a rdfs:Class ; rdfs:label "Homo" ; rdfs:subClassOf obo:NCBITaxon_207598 . obo:CHEBI_32442 a rdfs:Class ; rdfs:label "L-cysteinate(1-)" ; rdfs:comment "The L-enantiomer of cysteinate(1-)." ; rdfs:subClassOf obo:CHEBI_32456 , obo:CHEBI_59814 . obo:CHEBI_48585 a rdfs:Class ; rdfs:label "heteroarylpiperidine" ; rdfs:subClassOf obo:CHEBI_26151 . obo:PR_P23975 a rdfs:Class ; rdfs:label "sodium-dependent noradrenaline transporter (human)" ; rdfs:comment "A sodium-dependent noradrenaline transporter that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000015186 , obo:PR_000029067 . obo:CHEBI_24026 a rdfs:Class ; rdfs:label "fatty alcohol" ; rdfs:comment "An aliphatic alcohol consisting of a chain of 3 to greater than 27 carbon atoms. Fatty alcohols may be saturated or unsaturated and may be branched or unbranched." ; rdfs:subClassOf obo:CHEBI_30879 , obo:CHEBI_61697 . obo:CIDO_0000285 a rdfs:Class ; rdfs:label "coronavirus life cycle stage"@en ; rdfs:subClassOf obo:CIDO_0000284 . obo:CHEBI_24803 a rdfs:Class ; rdfs:label "indole-3-acetic acids" ; rdfs:comment "An indol-3-yl carboxylic acid in which the carboxylic acid specified is acetic acid." ; rdfs:subClassOf obo:CHEBI_24810 . a rdfs:Class ; rdfs:label "Gonadal Hormones [Chemical/Ingredient]" ; rdfs:subClassOf . obo:CIDO_0020262 a rdfs:Class ; rdfs:label "RealStar SARS-CoV02 RT-PCR Kits" ; rdfs:seeAlso ; rdfs:subClassOf obo:CIDO_0000454 . obo:CHEBI_50792 a rdfs:Class ; rdfs:label "estrogen receptor antagonist" ; rdfs:comment "An antagonist at the estrogen receptor." ; rdfs:subClassOf obo:CHEBI_23888 , obo:CHEBI_48706 . obo:CHEBI_36416 a rdfs:Class ; rdfs:label "mancude organic heterotricyclic parent" ; rdfs:subClassOf obo:CHEBI_26979 , obo:CHEBI_35571 . obo:CHEBI_38496 a rdfs:Class ; rdfs:label "electron-transport chain inhibitor" ; rdfs:subClassOf obo:CHEBI_76932 . obo:PR_P49902 a rdfs:Class ; rdfs:label "cytosolic purine 5'-nucleotidase (human)" ; rdfs:comment "A cytosolic purine 5'-nucleotidase that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000011454 , obo:PR_000029067 . obo:PR_P54764 a rdfs:Class ; rdfs:label "ephrin type-A receptor 4 (human)" ; rdfs:comment "An ephrin type-A receptor 4 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000007124 , obo:PR_000029067 . a rdfs:Class ; rdfs:label "Carcinoma, Pancreatic Ductal [Disease/Finding]" ; rdfs:subClassOf , . obo:NCBITaxon_864609 a rdfs:Class ; rdfs:label "Bat coronavirus BR98-12/BGR/2008" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:PR_000011469 a rdfs:Class ; rdfs:label "high affinity nerve growth factor receptor" ; rdfs:comment "A TRK receptor that is a translation product of the human NTRK1 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000021997 . obo:CHEBI_71031 a rdfs:Class ; rdfs:label "orphan drug" ; rdfs:comment "Any drug that has been developed specifically for treatment of a rare medical condition, the condition itself being known as an orphan disease." ; rdfs:subClassOf obo:CHEBI_23888 . obo:NCBITaxon_31629 a rdfs:Class ; rdfs:label "Avian infectious bronchitis virus (strain UK/183/66)" ; rdfs:subClassOf obo:NCBITaxon_11120 . obo:NCBITaxon_2586420 a rdfs:Class ; rdfs:label "Tylonycteris bat coronavirus HKU33" ; rdfs:subClassOf obo:NCBITaxon_2727852 . obo:NCBITaxon_1052262 a rdfs:Class ; rdfs:label "Bat coronavirus M.ful/Japan/03/2009" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:CIDO_0020193 a rdfs:Class ; rdfs:label "LumiraDx SARS-CoV-2 RNA STAR Complete" ; rdfs:seeAlso ; rdfs:subClassOf obo:CIDO_0000454 . obo:CIDO_0000864 a rdfs:Class ; rdfs:label "SARS-CoV2 nsp14 protein binding to human IMPDH2" ; rdfs:comment "SARS-CoV2 nsp14 protein binding to human IMPDH2, as evidented by an affinity-purification mass spectrometry experiment" ; rdfs:subClassOf obo:CIDO_0000059 . obo:CHEBI_146000 a rdfs:Class ; rdfs:label "emetine dihydrochloride hydrate" ; rdfs:comment "A hydrate that is the monohydrate of the dihydrochloride salt of emetine." ; rdfs:subClassOf obo:CHEBI_35505 , obo:CHEBI_36807 . obo:CIDO_0000152 a rdfs:Class ; rdfs:label "COVID-19 pandemic"@en ; rdfs:subClassOf obo:CIDO_0000151 . a rdfs:Class ; rdfs:label "Atrial Fibrillation [Disease/Finding]" ; rdfs:subClassOf . obo:CHEBI_35646 a rdfs:Class ; rdfs:label "galanthan" ; rdfs:subClassOf obo:CHEBI_38511 , obo:CHEBI_38513 . obo:NCBITaxon_864612 a rdfs:Class ; rdfs:label "Bat coronavirus BR98-30/BGR/2008" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:NCBITaxon_35500 a rdfs:Class ; rdfs:label "Pecora" ; rdfs:subClassOf obo:NCBITaxon_9845 . obo:NCBITaxon_903606 a rdfs:Class ; rdfs:label "Kenya bat coronavirus BtKY68" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:CHEBI_36389 a rdfs:Class ; rdfs:label "saturated organic heteromonocyclic parent" ; rdfs:subClassOf obo:CHEBI_25693 , obo:CHEBI_36388 . obo:OPMI_0000542 a rdfs:Class ; rdfs:label "admission diagnosis status"@en ; rdfs:comment "An admitting diagnosis is defined as the initial working diagnosis documented by the patient's admitting or attending physician who determined that inpatient care was necessary." ; rdfs:subClassOf obo:OPMI_0000533 . obo:GO_0042101 a rdfs:Class ; rdfs:label "T cell receptor complex" ; rdfs:comment "A protein complex that contains a disulfide-linked heterodimer of T cell receptor (TCR) chains, which are members of the immunoglobulin superfamily, and mediates antigen recognition, ultimately resulting in T cell activation. The TCR heterodimer is associated with the CD3 complex, which consists of the nonpolymorphic polypeptides gamma, delta, epsilon, zeta, and, in some cases, eta (an RNA splice variant of zeta) or Fc epsilon chains." ; rdfs:subClassOf obo:OBI_1110022 . obo:PR_000027234 a rdfs:Class ; rdfs:label "proto-oncogene tyrosine-protein kinase Src" ; rdfs:comment "A proto-oncogene SRC-like tyrosine-protein kinase that is a translation product of the human SRC gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000002997 . obo:NCBITaxon_258965 a rdfs:Class ; rdfs:label "SARS coronavirus TW2" ; rdfs:subClassOf obo:NCBITaxon_694009 . obo:CIDO_0000349 a rdfs:Class ; rdfs:label "SARS-CoV-2 S binding to ACE2"@en ; rdfs:subClassOf obo:CIDO_0000060 , obo:CIDO_0000135 . obo:HP_0031671 a rdfs:Class ; rdfs:label "Typical atrial flutter" ; rdfs:comment "Typical atrial flutter is an organised atrial tachycardia. It can also be defined as a macroreentrant tachycardia confined to the right atrium. This arrhythmia has a 200-260 ms cycle length, although it may fluctuate depending on patient's previous treatment or ablation, congenital heart disease, etc. Ventricular rate response will be limited by the atrioventricular node conductions, usually presenting a 2:1 or 3:1 response, during atrial flutter. Typical (counter clockwise) flutter is associated with the common flutter pattern: a regular continuous undulation with dominant negative deflections in inferior leads II, III and aVF, often described also as a saw tooth pattern, and flat atrial deflections in leads I and aVL. Atrial deflections in V1 can be positive, biphasic or negative." ; rdfs:subClassOf obo:HP_0004749 . obo:CHEBI_136859 a rdfs:Class ; rdfs:label "pro-agent" ; rdfs:comment "A compound that, on administration, undergoes conversion by biochemical (enzymatic), chemical (possibly following an enzymatic step), or physical (e.g. photochemical) activation processes before becoming the active agent for which it is a pro-agent." ; rdfs:subClassOf obo:CHEBI_33232 . obo:NCBITaxon_1269294 a rdfs:Class ; rdfs:label "Coronavirus BtCoV/BRA114/Car_bre/BRA/2009" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:VO_0005252 a rdfs:Class ; rdfs:label "ReCOV"@en ; rdfs:comment "A SARS-CoV-2 subunit vaccine by Jiangsu Rec-Biotechnology Co., Ltd." ; rdfs:subClassOf obo:VO_0005202 . obo:CIDO_0000819 a rdfs:Class ; rdfs:label "SARS-CoV2 nsp12 protein binding to human UBAP2L" ; rdfs:comment "SARS-CoV2 nsp12 protein binding to human UBAP2L, as evidented by an affinity-purification mass spectrometry experiment" ; rdfs:subClassOf obo:CIDO_0000057 . obo:OPMI_0000551 a rdfs:Class ; rdfs:label "condition to be diagnosed by procedure status"@en ; rdfs:subClassOf obo:OPMI_0000533 . obo:CHEBI_49 a rdfs:Class ; rdfs:label "(+)-Tetrandrine" ; rdfs:subClassOf obo:CHEBI_133004 , obo:CHEBI_24922 . obo:HP_0031258 a rdfs:Class ; rdfs:label "Delirium" ; rdfs:comment "A state of sudden and severe confusion." ; rdfs:subClassOf obo:HP_0004372 . obo:OGG_3000006351 a rdfs:Class ; rdfs:label "CCL4" ; rdfs:comment "Other designations: C-C motif chemokine 4|G-26 T-lymphocyte-secreted protein|MIP-1-beta(1-69)|PAT 744|SIS-gamma|T-cell activation protein 2|lymphocyte activation gene 1 protein|macrophage inflammatory protein 1-beta|secreted protein G-26|small inducible cytokine A4 (homologous to mouse Mip-1b)" ; rdfs:subClassOf obo:OGG_2060009606 . obo:UBERON_0006618 a rdfs:Class ; rdfs:label "atrium auricular region" ; rdfs:comment "A small conical pouch projections located on the upper anterior portion of each atrium of the heart." ; rdfs:subClassOf obo:UBERON_0000481 . obo:PR_000036194 a rdfs:Class ; rdfs:label "eukaryotic protein" ; rdfs:comment "A protein that is encoded in the genome of some Eukaryota." ; rdfs:subClassOf obo:PR_000000001 . obo:CHEBI_35107 a rdfs:Class ; rdfs:label "azane" ; rdfs:comment "Saturated acyclic nitrogen hydrides having the general formula NnHn+2." ; rdfs:subClassOf obo:CHEBI_35106 . obo:PR_P04049 a rdfs:Class ; rdfs:label "RAF proto-oncogene serine/threonine-protein kinase (human)" ; rdfs:comment "A RAF proto-oncogene serine/threonine-protein kinase that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000003244 , obo:PR_000029067 . obo:NCBITaxon_12760 a rdfs:Class ; rdfs:label "Murine hepatitis virus strain 4" ; rdfs:subClassOf obo:NCBITaxon_11138 . obo:CHEBI_95341 a rdfs:Class ; rdfs:label "baricitinib" ; rdfs:comment "A pyrrolopyrimidine that is 7H-pyrrolo[2,3-d]pyrimidine substituted by a 1-[3-(cyanomethyl)-1-(ethanesulfonyl)azetidin-3-yl]-1H-pyrazol-4-yl group at position 5. It is an FDA approved selective Janus Kinase 1 and 2 (JAK1 and JAK2) inhibitor used for the treatment of rheumatoid arthritis." ; rdfs:subClassOf obo:CHEBI_18379 , obo:CHEBI_26410 , obo:CHEBI_35358 , obo:CHEBI_38670 , obo:CHEBI_38777 . obo:NCBITaxon_756644 a rdfs:Class ; rdfs:label "Bovine coronavirus cow/WDBR-923/BRA/2003" ; rdfs:subClassOf obo:NCBITaxon_11128 . obo:PR_000009196 a rdfs:Class ; rdfs:label "tyrosine-protein kinase JAK1" ; rdfs:comment "A Janus kinase that is a translation product of the human JAK1 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000025748 . obo:GO_0021756 a rdfs:Class ; rdfs:label "striatum development" ; rdfs:comment "The progression of the striatum over time from its initial formation until its mature state. The striatum is a region of the forebrain consisting of the caudate nucleus, putamen and fundus striati." ; rdfs:subClassOf obo:GO_0048856 . obo:NCBITaxon_389236 a rdfs:Class ; rdfs:label "Bat coronavirus (BtCoV/311A /2005)" ; rdfs:subClassOf obo:NCBITaxon_389126 . obo:CIDO_0000936 a rdfs:Class ; rdfs:label "SARS-CoV2 nsp8 protein binding to human MRPS25" ; rdfs:comment "SARS-CoV2 nsp8 protein binding to human MRPS25, as evidented by an affinity-purification mass spectrometry experiment" ; rdfs:subClassOf obo:CIDO_0000582 . obo:PR_O14920 a rdfs:Class ; rdfs:label "inhibitor of nuclear factor kappa-B kinase subunit beta (human)" ; rdfs:comment "An inhibitor of nuclear factor kappa-B kinase subunit beta that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000001776 , obo:PR_000029067 . a rdfs:Class ; rdfs:label "TOCILIZUMAB" ; rdfs:subClassOf . obo:NCBITaxon_1679909 a rdfs:Class ; rdfs:label "Coronavirus RCoV/KS11_0997/Apo_agr/GER/2011" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:CIDO_0000397 a rdfs:Class ; rdfs:label "SARS-CoV-2 B.1.135.3 virus"@en ; rdfs:subClassOf obo:CIDO_0000406 . obo:NCBITaxon_497933 a rdfs:Class ; rdfs:label "Bat coronavirus M.das/Germany/D3.5/2007" ; rdfs:subClassOf obo:NCBITaxon_366617 . obo:CIDO_0000544 a rdfs:Class ; rdfs:label "SNSNYLLEEFDVVFG" ; rdfs:comment "A coronavirus epitope that is part of some S protein from HCoV 229E composed of the following amino acids SNSNYLLEEFDVVFG" ; rdfs:subClassOf obo:CIDO_0000451 . obo:NCBITaxon_903576 a rdfs:Class ; rdfs:label "Kenya bat coronavirus BtKY108" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:CIDO_0000055 a rdfs:Class ; rdfs:label "SARS-CoV-2 M protein interaction with host protein"@en ; rdfs:comment "A molecular interaction that has participant of the SARS-CoV-2 M protein and a host protein" ; rdfs:subClassOf obo:CIDO_0000348 . obo:NCBITaxon_2419667 a rdfs:Class ; rdfs:label "Bat alphacoronavirus" ; rdfs:subClassOf obo:NCBITaxon_366617 . obo:CHEBI_59770 a rdfs:Class ; rdfs:label "cyclic acetal" ; rdfs:comment "An acetal in the molecule of which the acetal carbon and one or both oxygen atoms thereon are members of a ring." ; rdfs:subClassOf obo:CHEBI_24532 , obo:CHEBI_59769 . obo:NCBITaxon_1034320 a rdfs:Class ; rdfs:label "Rm-Bat-CoV 429/2007/MV" ; rdfs:subClassOf obo:NCBITaxon_366617 . obo:OPMI_0000163 a rdfs:Class ; rdfs:label "care provider"@en ; rdfs:subClassOf obo:NCBITaxon_9606 . obo:CHEBI_72588 a rdfs:Class ; rdfs:label "semisynthetic derivative" ; rdfs:comment "Any organic molecular entity derived from a natural product by partial chemical synthesis." ; rdfs:subClassOf obo:CHEBI_50860 . obo:PR_Q9HCE1 a rdfs:Class ; rdfs:label "helicase MOV-10 (human)" ; rdfs:comment "A helicase MOV-10 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000029067 , obo:PR_000031651 . obo:OAE_0000570 a rdfs:Class ; rdfs:label "nervous system AE" ; rdfs:comment "an AE that occurs in nervous system." ; rdfs:subClassOf obo:OAE_0000001 . obo:NCBITaxon_1679917 a rdfs:Class ; rdfs:label "Coronavirus RCoV/RMU10_3052/Apo_fla/GER/2010" ; rdfs:subClassOf obo:NCBITaxon_2664420 . a rdfs:Class ; rdfs:label "Demographic States [Disease/Finding]" ; rdfs:subClassOf . obo:OPMI_0000503 a rdfs:Class ; rdfs:label "National Provider Identifier"@en ; rdfs:comment "A centrally registered identifier that refers to the National Provider Number issued to health care providers in the US by the Centers for Medicare and Medicaid Services (CMS). NPI is assigned for use in all administrative and financial transactions specified by HIPAA." ; rdfs:subClassOf obo:IAO_0000578 . a rdfs:Class ; rdfs:label "Histamine Receptor Interactions [MoA]" ; rdfs:subClassOf . obo:CHEBI_77255 a rdfs:Class ; rdfs:label "EC 3.4.24.83 (anthrax lethal factor endopeptidase) inhibitor" ; rdfs:comment "An EC 3.4.24.* (metalloendopeptidase) inhibitor that interferes with the action of anthrax lethal factor endopeptidase (EC 3.4.24.83)." ; rdfs:subClassOf obo:CHEBI_59107 . obo:HP_0031247 a rdfs:Class ; rdfs:label "Whooping cough" ; rdfs:comment "A type of cough characterized by a burst of numerous and rapid coughs followed by a long inhaling effort that is accompanied by a high-pitched whooping sound produced by the inhalation of air." ; rdfs:subClassOf obo:HP_0012735 . obo:CIDO_0001133 a rdfs:Class ; rdfs:label "SARS-CoV2 orf8 protein binding to human PVR"@en ; rdfs:comment "SARS-CoV2 orf8 protein binding to human PVR, as evidented by an affinity-purification mass spectrometry experiment" ; rdfs:subClassOf obo:CIDO_0000051 . obo:CIDO_0020077 a rdfs:Class ; rdfs:label "Clear Dx SARS-CoV-2 Test" ; rdfs:seeAlso ; rdfs:subClassOf obo:CIDO_0000454 . obo:PR_000003106 a rdfs:Class ; rdfs:label "map kinase p38" ; rdfs:comment "A protein that is a serine/threonine-specific protein kinase that responds to extracellular stimuli (environmental stress, pro-inflammatory cytokines and lipopolysaccharide) and regulates cellular activities such as gene expression, mitosis, differentiation, and cell survival/apoptosis. The activated form phosphorylates target substrates on Ser or Thr residues followed by a proline. A distinguishing feature is the conserved sequence TxY." ; rdfs:subClassOf obo:PR_000000001 . obo:OPMI_0000516 a rdfs:Class ; rdfs:label "provenance of death record"@en ; rdfs:comment "A provenance of record that determines the provenance of the death record, i.e., where it came from." ; rdfs:subClassOf obo:OPMI_0000512 . a rdfs:Class ; rdfs:label "Endocarditis, Bacterial [Disease/Finding]" ; rdfs:subClassOf , , . a rdfs:Class ; rdfs:label "Increased Immunologically Active Molecule Activity [PE]" ; rdfs:subClassOf , . obo:CHEBI_71554 a rdfs:Class ; rdfs:label "PPARgamma agonist" ; rdfs:comment "A PPAR modulator which activates the peroxisome proliferator-activated receptor-gamma." ; rdfs:subClassOf obo:CHEBI_48705 , obo:CHEBI_70781 . obo:CIDO_0020315 a rdfs:Class ; rdfs:label "UMass Molecular Virology Laboratory 2019-nCoV rRT-PCR Dx Panel" ; rdfs:seeAlso ; rdfs:subClassOf obo:CIDO_0000454 . obo:DOID_7 a rdfs:Class ; rdfs:label "disease of anatomical entity" ; rdfs:comment "A disease that manifests in a defined anatomical structure." ; rdfs:subClassOf obo:DOID_4 . obo:CIDO_0000651 a rdfs:Class ; rdfs:label "V145- in SARS-CoV-2 S protein"@en ; rdfs:comment "An AA mutation or AA variant that has mutated an amino acid at position 145 in S protein into a deletion." ; rdfs:subClassOf obo:CIDO_0001144 . obo:UBERON_0001004 a rdfs:Class ; rdfs:label "respiratory system" ; rdfs:comment "Functional system which consists of structures involved in respiration." ; rdfs:subClassOf obo:UBERON_0000465 . obo:PR_O95819 a rdfs:Class ; rdfs:label "mitogen-activated protein kinase kinase kinase kinase 4 (human)" ; rdfs:comment "A mitogen-activated protein kinase kinase kinase kinase 4 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000003043 , obo:PR_000029067 . obo:CHEBI_33833 a rdfs:Class ; rdfs:label "heteroarene" ; rdfs:comment "A heterocyclic compound formally derived from an arene by replacement of one or more methine (-C=) and/or vinylene (-CH=CH-) groups by trivalent or divalent heteroatoms, respectively, in such a way as to maintain the continuous pi-electron system characteristic of aromatic systems and a number of out-of-plane pi-electrons corresponding to the Hueckel rule (4n+2)." ; rdfs:subClassOf obo:CHEBI_24532 , obo:CHEBI_33659 . obo:NCBITaxon_389148 a rdfs:Class ; rdfs:label "Bat coronavirus (BtCoV/860/2005)" ; rdfs:subClassOf obo:NCBITaxon_389126 . obo:CHEBI_24400 a rdfs:Class ; rdfs:label "glycoside" ; rdfs:comment "A glycosyl compound resulting from the attachment of a glycosyl group to a non-acyl group RO-, RS-, RSe-, etc. The bond between the glycosyl group and the non-acyl group is called a glycosidic bond. By extension, the terms N-glycosides and C-glycosides are used as class names for glycosylamines and for compounds having a glycosyl group attached to a hydrocarbyl group respectively. These terms are misnomers and should not be used. The preferred terms are glycosylamines and C-glycosyl compounds, respectively." ; rdfs:subClassOf obo:CHEBI_63161 . obo:NCBITaxon_393768 a rdfs:Class ; rdfs:label "Bat coronavirus 1B" ; rdfs:subClassOf obo:NCBITaxon_694000 . obo:VO_0005308 a rdfs:Class ; rdfs:label "immune response profile"@en ; rdfs:subClassOf obo:BFO_0000144 . obo:PR_000015289 a rdfs:Class ; rdfs:label "SPARC-related modular calcium-binding protein 1" ; rdfs:comment "A protein that is a translation product of the human SMOC1 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:NCBITaxon_1649337 a rdfs:Class ; rdfs:label "Duck-dominant coronavirus" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:PR_P06239 a rdfs:Class ; rdfs:label "tyrosine-protein kinase Lck (human)" ; rdfs:comment "A tyrosine-protein kinase Lck that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000002998 , obo:PR_000029067 . obo:NCBITaxon_253434 a rdfs:Class ; rdfs:label "SARS coronavirus PUMC02" ; rdfs:subClassOf obo:NCBITaxon_694009 . obo:NCBITaxon_2042587 a rdfs:Class ; rdfs:label "Coronavirus PREDICT CoV-63" ; rdfs:subClassOf obo:NCBITaxon_366617 . obo:CHEBI_24433 a rdfs:Class ; rdfs:label "group" ; rdfs:comment "A defined linked collection of atoms or a single atom within a molecular entity." ; rdfs:subClassOf obo:CHEBI_24431 . obo:NCBITaxon_249070 a rdfs:Class ; rdfs:label "SARS coronavirus HSZ-Bb" ; rdfs:subClassOf obo:NCBITaxon_694009 . obo:PR_000001779 a rdfs:Class ; rdfs:label "serine/threonine-protein kinase TBK1" ; rdfs:comment "An IKK-related kinase that is a translation product of the human TBK1 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000001777 . obo:NCBITaxon_293321 a rdfs:Class ; rdfs:label "SARS coronavirus GZ0403" ; rdfs:subClassOf obo:NCBITaxon_694009 . obo:GO_0034660 a rdfs:Class ; rdfs:label "ncRNA metabolic process" ; rdfs:comment "The chemical reactions and pathways involving non-coding RNA transcripts (ncRNAs)." ; rdfs:subClassOf obo:GO_0016070 . obo:HP_0001664 a rdfs:Class ; rdfs:label "Torsade de pointes" ; rdfs:comment "A type of ventricular tachycardia characterized by polymorphioc QRS complexes that change in amplitue and cycle length, and thus have the appearance of oscillating around the baseline in the EKG." ; rdfs:subClassOf obo:HP_0004308 . obo:NCBITaxon_1986197 a rdfs:Class ; rdfs:label "unclassified Coronaviridae" ; rdfs:subClassOf obo:NCBITaxon_11118 . a rdfs:Class ; rdfs:label "Stilbenes [Chemical/Ingredient]" ; rdfs:subClassOf . obo:CHEBI_65190 a rdfs:Class ; rdfs:label "first generation antipsychotic" ; rdfs:comment "Antipsychotic drugs which can have different modes of action but which tend to be more likely than second generation antipsychotics to cause extrapyramidal motor control disabilities such as body rigidity or Parkinson's disease-type movements; such body movements can become permanent even after treatment has ceased." ; rdfs:subClassOf obo:CHEBI_35476 . obo:PR_000013216 a rdfs:Class ; rdfs:label "DNA primase large subunit" ; rdfs:comment "A protein that is a translation product of the human PRIM2 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:CIDO_0000616 a rdfs:Class ; rdfs:label "AA variant in SARS-CoV-2 NS3 protein"@en ; rdfs:subClassOf obo:CIDO_0000237 . obo:CHEBI_48120 a rdfs:Class ; rdfs:label "anthracycline" ; rdfs:comment "Anthracyclines are polyketides that have a tetrahydronaphthacenedione ring structure attached by a glycosidic linkage to the amino sugar daunosamine." ; rdfs:subClassOf obo:CHEBI_26188 . obo:GO_0051937 a rdfs:Class ; rdfs:label "catecholamine transport" ; rdfs:comment "The directed movement of catecholamines, a group of physiologically important biogenic amines that possess a catechol (3,4-dihydroxyphenyl) nucleus and are derivatives of 3,4-dihydroxyphenylethylamine." ; rdfs:subClassOf obo:GO_0015844 , obo:GO_0015850 . a rdfs:Class ; rdfs:label "Polycyclic Compounds [Chemical/Ingredient]" ; rdfs:subClassOf . a rdfs:Class ; rdfs:label "Small Intestine Fluid/Electrolyte Absorption Alteration [PE]" ; rdfs:subClassOf . obo:OAE_0000362 a rdfs:Class ; rdfs:label "rash AE" ; rdfs:comment "a skin AE that shows the symptom of rash, i.e., an abnormal change in skin color, appearance, or texture. A rash may cause the skin to change color, itch, become warm, bumpy, dry, cracked or blistered, swell and may be painful." ; rdfs:subClassOf obo:OAE_0000543 . obo:PR_Q14181 a rdfs:Class ; rdfs:label "DNA polymerase alpha subunit B (human)" ; rdfs:comment "A DNA polymerase alpha subunit B that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000012961 , obo:PR_000029067 . obo:GO_0032872 a rdfs:Class ; rdfs:label "regulation of stress-activated MAPK cascade" ; rdfs:comment "Any process that modulates the frequency, rate or extent of signal transduction mediated by the stress-activated MAPK cascade." ; rdfs:subClassOf obo:GO_0043408 , obo:GO_0070302 . obo:CHEBI_29917 a rdfs:Class ; rdfs:label "thiol group" ; rdfs:subClassOf obo:CHEBI_33246 . obo:IDO_0000499 a rdfs:Class ; rdfs:label "vaccination against infectious agent"@en ; rdfs:comment "An active immunization that begins with exposure of an organism to a vaccine."@en ; rdfs:subClassOf obo:IDO_0000498 . obo:PR_Q96F45 a rdfs:Class ; rdfs:label "zinc finger protein 503 (human)" ; rdfs:comment "A zinc finger protein 503 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000017938 , obo:PR_000029067 . a rdfs:Class ; rdfs:label "Sulfhydryl Compounds [Chemical/Ingredient]" ; rdfs:subClassOf . a rdfs:Class ; rdfs:label "Cholinergic Muscarinic Antagonists [MoA]" ; rdfs:subClassOf , . obo:CIDO_0000592 a rdfs:Class ; rdfs:label "AA variant in SARS-CoV-2 S protein S1 region"@en ; rdfs:comment "An AA variant that is located in the S1 domain of SARS-CoV-2 S protein. In the original Wuhan strain, this contains amino acids from positions 1-685." ; rdfs:subClassOf obo:CIDO_0000591 . obo:CHEBI_34996 a rdfs:Class ; rdfs:label "teicoplanin A2-3" ; rdfs:comment "A teicoplanin A2 that has decanoyl as the variable N-acyl group." ; rdfs:subClassOf obo:CHEBI_34994 . obo:PR_P07203 a rdfs:Class ; rdfs:label "glutathione peroxidase 1 (human)" ; rdfs:comment "A glutathione peroxidase 1 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000008210 , obo:PR_000029067 . obo:GO_0032991 a rdfs:Class ; rdfs:label "protein-containing complex" ; rdfs:comment "A stable assembly of two or more macromolecules, i.e. proteins, nucleic acids, carbohydrates or lipids, in which at least one component is a protein and the constituent parts function together." ; rdfs:subClassOf obo:BFO_0000040 . obo:UBERON_0001970 a rdfs:Class ; rdfs:label "bile" ; rdfs:comment "vital aqueous secretion of the liver that is formed by hepatocytes and modified down stream by absorptive and secretory properties of the bile duct epithelium." ; rdfs:subClassOf obo:UBERON_0006314 . obo:CHEBI_36848 a rdfs:Class ; rdfs:label "5-hydroxy steroid" ; rdfs:subClassOf obo:CHEBI_35350 . obo:NCBITaxon_2042604 a rdfs:Class ; rdfs:label "Kenya bat coronavirus/BtKY56/BtKY55" ; rdfs:subClassOf obo:NCBITaxon_696098 . a rdfs:Class ; rdfs:label "Decreased Cell Membrane Integrity [PE]" ; rdfs:subClassOf . obo:CHEBI_46920 a rdfs:Class ; rdfs:label "N-methylpiperazine" ; rdfs:subClassOf obo:CHEBI_46845 , obo:CHEBI_50996 . a rdfs:Class ; rdfs:label "Hormone Receptor Modulators [MoA]" ; rdfs:subClassOf . a rdfs:Class ; rdfs:label "Skin Diseases, Parasitic [Disease/Finding]" ; rdfs:subClassOf , . obo:CHEBI_35701 a rdfs:Class ; rdfs:label "ester" ; rdfs:comment "A compound formally derived from an oxoacid RkE(=O)l(OH)m (l > 0) and an alcohol, phenol, heteroarenol, or enol by linking with formal loss of water from an acidic hydroxy group of the former and a hydroxy group of the latter." ; rdfs:subClassOf obo:CHEBI_36963 , obo:CHEBI_50860 . obo:DRON_00013637 a rdfs:Class ; rdfs:label "Interferon Alfa-n1" ; rdfs:subClassOf obo:OBI_0000047 . obo:CIDO_0020284 a rdfs:Class ; rdfs:label "ScienCell SARS-CoV-2 Coronavirus Real-time RT-PCR (RT-qPCR) Detection Kit" ; rdfs:seeAlso ; rdfs:subClassOf obo:CIDO_0000454 . obo:NCBITaxon_1346301 a rdfs:Class ; rdfs:label "Betacoronavirus BtCoV/Rhi_fer/FR0711-B3/FRA/2011" ; rdfs:subClassOf obo:NCBITaxon_696098 . obo:NCBITaxon_231419 a rdfs:Class ; rdfs:label "Bovine coronavirus LSU" ; rdfs:subClassOf obo:NCBITaxon_11128 . obo:NCBITaxon_749423 a rdfs:Class ; rdfs:label "Brent goose coronavirus KR-69" ; rdfs:subClassOf obo:NCBITaxon_749416 . obo:CHEBI_134722 a rdfs:Class ; rdfs:label "favipiravir" ; rdfs:comment "A member of the class of pyrazines that is pyrazine substituted by aminocarbonyl, hydroxy and fluoro groups at positions 2, 3 and 6, respectively. It is an anti-viral agent that inhibits RNA-dependent RNA polymerase of several RNA viruses and is approved for the treatment of influenza in Japan." ; rdfs:subClassOf obo:CHEBI_140324 , obo:CHEBI_37143 , obo:CHEBI_71633 . obo:PATO_0001894 a rdfs:Class ; rdfs:label "phenotypic sex" ; rdfs:comment "An organismal quality inhering in a bearer by virtue of the bearer's physical expression of sexual characteristics." ; rdfs:subClassOf obo:BFO_0000020 . obo:VO_0005400 a rdfs:Class ; rdfs:label "Prime-2-CoV-Beta"@en ; rdfs:comment "A SARS-CoV-2 protein subunit vaccine manufactured by Speransa Therapeutics." ; rdfs:subClassOf obo:VO_0005202 . a rdfs:Class ; rdfs:label "Leukoencephalopathies [Disease/Finding]" ; rdfs:subClassOf . a rdfs:Class ; rdfs:label "Spirurida Infections [Disease/Finding]" ; rdfs:subClassOf . obo:CIDO_0000644 a rdfs:Class ; rdfs:label "T1001I in SARS-CoV-2 pp1a protein" ; rdfs:comment "An AA mutation or AA variant that has mutated an amino acid at position 1001 into a isoleucine in pp1a." ; rdfs:subClassOf obo:CIDO_0001074 . obo:HP_0004756 a rdfs:Class ; rdfs:label "Ventricular tachycardia" ; rdfs:comment "A tachycardia originating in the ventricles characterized by rapid heart rate (over 100 beats per minute) and broad QRS complexes (over 120 ms)." ; rdfs:subClassOf obo:HP_0001649 . a rdfs:Class ; rdfs:label "Purinones [Chemical/Ingredient]" ; rdfs:subClassOf . obo:CHEBI_30746 a rdfs:Class ; rdfs:label "benzoic acid" ; rdfs:comment "A compound comprising a benzene ring core carrying a carboxylic acid substituent." ; rdfs:subClassOf obo:CHEBI_22723 . obo:UBERON_0002185 a rdfs:Class ; rdfs:label "bronchus" ; rdfs:comment "the upper conducting airways of the lung; these airways arise from the terminus of the trachea" ; rdfs:subClassOf obo:UBERON_0000117 . obo:OAE_0000378 a rdfs:Class ; rdfs:label "respiratory system AE" ; rdfs:comment "an AE that occurs in respiratory system." ; rdfs:subClassOf obo:OAE_0000001 . a rdfs:Class ; rdfs:label "Ergot Alkaloids [Chemical/Ingredient]" ; rdfs:subClassOf . obo:DOID_0070078 a rdfs:Class ; rdfs:label "schizophrenia 2" ; rdfs:comment "A schizophrenia that has_material_basis_in an autosomal dominant mutation of SCZD2 on chromosome 11q14-q21." ; rdfs:subClassOf obo:DOID_0050736 , obo:DOID_5419 . obo:NCBITaxon_1679925 a rdfs:Class ; rdfs:label "Coronavirus Rabbit_CoV/La09_24/Ory_cun/ESP/2009" ; rdfs:subClassOf obo:NCBITaxon_2664420 . a rdfs:Class ; rdfs:label "Amyloidosis [Disease/Finding]" ; rdfs:subClassOf . obo:OBI_0002514 a rdfs:Class ; rdfs:label "peritoneal fluid specimen" ; rdfs:comment "A specimen that is derived from peritoneal fluid." ; rdfs:subClassOf obo:OBI_2000009 . obo:NCBITaxon_2509500 a rdfs:Class ; rdfs:label "Myotacovirus" ; rdfs:subClassOf obo:NCBITaxon_693996 . obo:CHEBI_3048 a rdfs:Class ; rdfs:label "benzatropine" ; rdfs:comment "Tropane in which a hydrogen at position 3 is substituted by a diphenylmethoxy group (endo-isomer). An acetylcholine receptor antagonist, it is used (particularly as its methanesulphonate salt) in the treatment of Parkinson's disease, and to reduce parkinsonism and akathisia side effects of antipsychotic treatments." ; rdfs:subClassOf obo:CHEBI_50996 . obo:PR_000013236 a rdfs:Class ; rdfs:label "serine/threonine-protein kinase D1" ; rdfs:comment "A protein kinase D that is a translation product of the human PRKD1 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000045384 . obo:CIDO_0000627 a rdfs:Class ; rdfs:label "D3L in SARS-CoV-2 N protein" ; rdfs:comment "An AA mutation or AA variant that has mutated an amino acid at position 3 into a leucine in N protein." ; rdfs:subClassOf obo:CIDO_0000596 . obo:PR_000012222 a rdfs:Class ; rdfs:label "protein-arginine deiminase type-4" ; rdfs:comment "A protein that is a translation product of the human PADI4 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:HP_0005155 a rdfs:Class ; rdfs:label "Ventricular escape rhythm" ; rdfs:comment "A ventircular escape rhythm occurs whenever higher-lever pacemakers in AV junction or sinus node fail to control ventricular activation. Escape rate is usually 20-40 bpm, often associated with broad QRS complexes (at least 120 ms)." ; rdfs:subClassOf obo:HP_0004308 . obo:GO_0035556 a rdfs:Class ; rdfs:label "intracellular signal transduction" ; rdfs:comment "The process in which a signal is passed on to downstream components within the cell, which become activated themselves to further propagate the signal and finally trigger a change in the function or state of the cell." ; rdfs:subClassOf obo:GO_0007165 . obo:CIDO_0020201 a rdfs:Class ; rdfs:label "MD Anderson High-throughput SARS-CoV-2 RT-PCR Assay" ; rdfs:seeAlso ; rdfs:subClassOf obo:CIDO_0000454 . obo:OPMI_0000488 a rdfs:Class ; rdfs:label "visit end date"@en ; rdfs:comment "The date on which a visit ends. For inpatient visits the end date is typically the discharge date. If a Person is still an inpatient in the hospital at the time of the data extract and does not have a visit_end_date, then set the visit_end_date to the date of the data pull." ; rdfs:subClassOf obo:OPMI_0000285 . obo:CHEBI_72490 a rdfs:Class ; rdfs:label "2-(hydroxymethyl)piperidine-3,4,5-triol" ; rdfs:comment "A hydroxypiperidine that has three hydroxy groups located at positions 3, 4 and 5 as well as a hydroxymethyl substituent at position 2." ; rdfs:subClassOf obo:CHEBI_48590 . obo:NCBITaxon_1415848 a rdfs:Class ; rdfs:label "Bat SARS-like coronavirus Rs4105" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:PR_P11309 a rdfs:Class ; rdfs:label "serine/threonine-protein kinase pim-1 (human)" ; rdfs:comment "A proto-oncogene serine/threonine-protein kinase Pim-1 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000012732 , obo:PR_000029067 . obo:CIDO_0000684 a rdfs:Class ; rdfs:label "P26S in SARS-CoV-2 S protein" ; rdfs:comment "An AA mutation or AA variant that has mutated an amino acid at position 26 into a serine" ; rdfs:subClassOf obo:CIDO_0000594 . obo:CIDO_0000098 a rdfs:Class ; rdfs:label "interruption to coronaviral infection"@en ; rdfs:comment "A process that interrupts a viral infection in host" ; rdfs:subClassOf obo:CIDO_0000097 . obo:CHEBI_517248 a rdfs:Class ; rdfs:label "bufalin" ; rdfs:comment "A 14beta-hydroxy steroid that is bufan-20,22-dienolide having hydroxy substituents at the 5beta- and 14beta-positions. It has been isolated from the skin of the toad Bufo bufo." ; rdfs:subClassOf obo:CHEBI_36836 , obo:CHEBI_36862 . obo:PR_O96013 a rdfs:Class ; rdfs:label "serine/threonine-protein kinase PAK 4 (human)" ; rdfs:comment "A serine/threonine-protein kinase PAK 4 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000012243 , obo:PR_000029067 . obo:CHEBI_17822 a rdfs:Class ; rdfs:label "serine" ; rdfs:comment "An alpha-amino acid that is alanine substituted at position 3 by a hydroxy group." ; rdfs:subClassOf obo:CHEBI_26167 , obo:CHEBI_33704 . obo:OBI_0002539 a rdfs:Class ; rdfs:label "tibial nerve specimen" ; rdfs:comment "A specimen that is derived from tibial nerve." ; rdfs:subClassOf obo:OBI_0001479 . obo:NCBITaxon_76344 a rdfs:Class ; rdfs:label "Murine hepatitis virus strain 2" ; rdfs:subClassOf obo:NCBITaxon_11138 . obo:HP_0006671 a rdfs:Class ; rdfs:label "Paroxysmal atrial tachycardia" ; rdfs:subClassOf obo:HP_0004763 . obo:PR_000013591 a rdfs:Class ; rdfs:label "Ras-related protein Rab-1A" ; rdfs:comment "A protein that is a translation product of the human RAB1A gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . a rdfs:Class ; rdfs:label "Respiration Disorders [Disease/Finding]" ; rdfs:subClassOf . a rdfs:Class ; rdfs:label "Staphylococcal Skin Infections [Disease/Finding]" ; rdfs:subClassOf , . obo:PR_O00329 a rdfs:Class ; rdfs:label "phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (human)" ; rdfs:comment "A phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000012721 , obo:PR_000029067 . obo:NCBITaxon_1679895 a rdfs:Class ; rdfs:label "Coronavirus RCoV/D_RMU10_1993/Myo_gla/GER/2010" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:PR_Q6ZRP7 a rdfs:Class ; rdfs:label "sulfhydryl oxidase 2 (human)" ; rdfs:comment "A sulfhydryl oxidase 2 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000013575 , obo:PR_000029067 . obo:CIDO_0000064 a rdfs:Class ; rdfs:label "SARS-CoV-2 Nsp10 protein interaction with host protein"@en ; rdfs:comment "A molecular interaction that has participant of the SARS-CoV-2 Nsp10 protein and a host protein" ; rdfs:subClassOf obo:CIDO_0000348 . obo:VO_0001139 a rdfs:Class ; rdfs:label "vaccine organism viability" ; rdfs:comment "vaccine viability is a viability of a vaccine organism." ; rdfs:subClassOf obo:PATO_0000169 . obo:CIDO_0020035 a rdfs:Class ; rdfs:label "Atellica IM SARS-CoV-2 IgG (COV2G)" ; rdfs:seeAlso ; rdfs:subClassOf obo:CIDO_0000454 . obo:CIDO_0000324 a rdfs:Class ; rdfs:label "CPFGEVFNATRFASV"@en ; rdfs:subClassOf obo:CIDO_0000314 . obo:PR_Q02763 a rdfs:Class ; rdfs:label "angiopoietin-1 receptor (human)" ; rdfs:comment "An angiopoietin-1 receptor that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000002032 , obo:PR_000029067 . obo:NCBITaxon_166124 a rdfs:Class ; rdfs:label "Human enteric coronavirus 4408" ; rdfs:subClassOf obo:NCBITaxon_11128 . obo:NCBITaxon_249085 a rdfs:Class ; rdfs:label "SARS coronavirus LC3" ; rdfs:subClassOf obo:NCBITaxon_694009 . obo:CIDO_0000519 a rdfs:Class ; rdfs:label "KASSRSAIEDLLFDK" ; rdfs:comment "A coronavirus epitope that is part of some S protein from HCoV OC43 composed of the following amino acids KASSRSAIEDLLFDK" ; rdfs:subClassOf obo:CIDO_0000452 . obo:NCBITaxon_864594 a rdfs:Class ; rdfs:label "Bat coronavirus BM48-12/BGR/2008" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:PR_O43283 a rdfs:Class ; rdfs:label "mitogen-activated protein kinase kinase kinase 13 (human)" ; rdfs:comment "A mitogen-activated protein kinase kinase kinase 13 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000010132 , obo:PR_000029067 . obo:OBI_0100060 a rdfs:Class ; rdfs:label "cultured cell population" ; rdfs:comment "A processed material comprised of a collection of cultured cells that has been continuously maintained together in culture and shares a common propagation history." ; rdfs:subClassOf obo:OBI_0000047 . obo:OPMI_0000447 a rdfs:Class ; rdfs:label "cytokine biomarker"@en ; rdfs:subClassOf obo:OPMI_0000446 . obo:PR_000000028 a rdfs:Class ; rdfs:label "small GTPase" ; rdfs:comment "A protein with a core domain composition consisting of a Ras family domain (Pfam:PF00071). The small GTPases are monomeric G-proteins which function as GDP/GTP-regulated molecular switches." ; rdfs:subClassOf obo:PR_000000001 . obo:CIDO_0001227 a rdfs:Class ; rdfs:label "Multiple Real-Time PCR Kit for Detection of 2019-nCoV. (Zybio Inc.)" ; rdfs:comment "Poduct storage conditions and expiration date: Store in the dark at -20±5℃, valid for 12 months." ; rdfs:subClassOf obo:CIDO_0000021 . obo:PR_000017108 a rdfs:Class ; rdfs:label "regulator of nonsense transcripts 1" ; rdfs:comment "A protein that is a translation product of the human UPF1 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:CHEBI_29277 a rdfs:Class ; rdfs:label "dinitride(2-)" ; rdfs:subClassOf obo:CHEBI_33266 . obo:PR_000008473 a rdfs:Class ; rdfs:label "tyrosine-protein kinase HCK" ; rdfs:comment "A proto-oncogene SRC-like tyrosine-protein kinase that is a translation product of the human HCK gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000002997 . obo:NCBITaxon_1679906 a rdfs:Class ; rdfs:label "Coronavirus RCoV/KS10_2810/Mic_arv/GER/2010" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:CHEBI_132944 a rdfs:Class ; rdfs:label "octadec-9-enoate" ; rdfs:comment "An octadecenoate in which the double bond is at C-9." ; rdfs:subClassOf obo:CHEBI_78049 . obo:PR_Q96BR1 a rdfs:Class ; rdfs:label "serine/threonine-protein kinase Sgk3 (human)" ; rdfs:comment "A serine/threonine-protein kinase Sgk3 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000014794 , obo:PR_000029067 . obo:PR_O00444 a rdfs:Class ; rdfs:label "serine/threonine-protein kinase PLK4 (human)" ; rdfs:comment "A serine/threonine-protein kinase PLK4 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000012873 , obo:PR_000029067 . obo:UBERON_0001987 a rdfs:Class ; rdfs:label "placenta" ; rdfs:comment "organ of metabolic interchange between fetus and mother, partly of embryonic origin and partly of maternal origin[GO]. The fetal portion of the placenta is known as the villous chorion. The maternal portion is known as the decidua basalis. The two portions are held together by anchoring villi that are anchored to the decidua basalis by the cytotrophoblastic shell." ; rdfs:subClassOf obo:UBERON_0000465 . obo:DRON_00022632 a rdfs:Class ; rdfs:label "Nelfinavir Oral Tablet" ; rdfs:subClassOf obo:DRON_00000022 . a rdfs:Class ; rdfs:label "Inflammatory Bowel Diseases [Disease/Finding]" ; rdfs:subClassOf , . obo:CHEBI_17258 a rdfs:Class ; rdfs:label "7H-purine" ; rdfs:comment "The 7H-tautomer of purine." ; rdfs:subClassOf obo:CHEBI_35584 . obo:CIDO_0020252 a rdfs:Class ; rdfs:label "Quest Diagnostics PF SARS-CoV-2 Assay" ; rdfs:seeAlso ; rdfs:subClassOf obo:CIDO_0000454 . obo:UBERON_0000029 a rdfs:Class ; rdfs:label "lymph node" ; rdfs:comment "Any of the rounded masses of lymphoid tissue that are surrounded by a capsule of connective tissue, are distributed along the lymphatic vessels, and contain numerous lymphocytes which filter the flow of lymph." ; rdfs:subClassOf obo:UBERON_0000465 . obo:NCBITaxon_756650 a rdfs:Class ; rdfs:label "Bovine coronavirus cow/WDBR-9224/BRA/2003" ; rdfs:subClassOf obo:NCBITaxon_11128 . obo:DRON_00015957 a rdfs:Class ; rdfs:label "Niclosamide" ; rdfs:subClassOf obo:OBI_0000047 . obo:CIDO_0000667 a rdfs:Class ; rdfs:label "E484A in SARS-CoV-2 S protein" ; rdfs:comment "An AA mutation or AA variant that has mutated an amino acid at position 484 into a alanine in S protein." ; rdfs:subClassOf obo:CIDO_0000593 . obo:PR_000044658 a rdfs:Class ; rdfs:label "voltage-gated calcium channel protein" ; rdfs:comment "A voltage-gated ion channel protein that has voltage-gated calcium channel activity. A voltage-gated calcium channel enables the transmembrane transfer of a calcium ion by a voltage-gated channel. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded." ; rdfs:subClassOf obo:PR_000044628 . a rdfs:Class ; rdfs:label "Depsipeptides [Chemical/Ingredient]" ; rdfs:subClassOf . obo:OBI_0000415 a rdfs:Class ; rdfs:label "polymerase chain reaction"@en ; rdfs:comment "PCR is the process in which a DNA polymerase is used to amplify a piece of DNA by in vitro enzymatic replication. As PCR progresses, the DNA thus generated is itself used as a template for replication. This sets in motion a chain reaction in which the DNA template is exponentially amplified."@en ; rdfs:subClassOf obo:OBI_0600058 . obo:CIDO_0020024 a rdfs:Class ; rdfs:label "Anti-SARS-CoV-2 Elisa (IgG)" ; rdfs:seeAlso ; rdfs:subClassOf obo:CIDO_0000454 . obo:CHEBI_35469 a rdfs:Class ; rdfs:label "antidepressant" ; rdfs:comment "Antidepressants are mood-stimulating drugs used primarily in the treatment of affective disorders and related conditions." ; rdfs:subClassOf obo:CHEBI_35471 . a rdfs:Class ; rdfs:label "Decreased Thromboxane Activity [PE]" ; rdfs:subClassOf . obo:CHEBI_24983 a rdfs:Class ; rdfs:label "ketoxime" ; rdfs:comment "Oximes of ketones R2C=NOH (where R =/= H)." ; rdfs:subClassOf obo:CHEBI_25750 . obo:CHEBI_24697 a rdfs:Class ; rdfs:label "hydroxyflavanone" ; rdfs:comment "A member of the class of flavanones that consists of flavanone with one or more hydroxy substituents." ; rdfs:subClassOf obo:CHEBI_28863 , obo:CHEBI_33822 . obo:NCBITaxon_385686 a rdfs:Class ; rdfs:label "SARS coronavirus ES260" ; rdfs:subClassOf obo:NCBITaxon_694009 . a rdfs:Class ; rdfs:label "Drug Products by Generic Ingredient Combinations" ; rdfs:subClassOf . obo:GO_0050867 a rdfs:Class ; rdfs:label "positive regulation of cell activation" ; rdfs:comment "Any process that activates or increases the frequency, rate or extent of activation." ; rdfs:subClassOf obo:GO_0048522 , obo:GO_0050865 . obo:PR_000002206 a rdfs:Class ; rdfs:label "mitogen-activated protein kinase 8" ; rdfs:comment "A protein that is a translation product of the human MAPK8 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:NCBITaxon_1788469 a rdfs:Class ; rdfs:label "Miniopterus bat coronavirus BtCoV/3767" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:CIDO_0001036 a rdfs:Class ; rdfs:label "PF-07321332, obsolete" ; rdfs:subClassOf obo:CIDO_0000409 . obo:PR_000013642 a rdfs:Class ; rdfs:label "Ras-related protein Rab-8A" ; rdfs:comment "A protein that is a translation product of the human RAB8A gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . a rdfs:Class ; rdfs:label "FLUPHENAZINE HYDROCHLORIDE" ; rdfs:subClassOf . obo:CHEBI_38824 a rdfs:Class ; rdfs:label "fluorocarbon" ; rdfs:comment "Compounds consisting wholly of fluorine and carbon." ; rdfs:subClassOf obo:CHEBI_37143 . obo:PR_Q9BSJ2 a rdfs:Class ; rdfs:label "gamma-tubulin complex component 2 (human)" ; rdfs:comment "A gamma-tubulin complex component 2 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000016827 , obo:PR_000029067 . obo:GO_0019438 a rdfs:Class ; rdfs:label "aromatic compound biosynthetic process" ; rdfs:comment "The chemical reactions and pathways resulting in the formation of aromatic compounds, any substance containing an aromatic carbon ring." ; rdfs:subClassOf obo:GO_0006725 , obo:GO_0044249 . obo:CHEBI_26509 a rdfs:Class ; rdfs:label "quinoline alkaloid" ; rdfs:subClassOf obo:CHEBI_22315 , obo:CHEBI_26513 . obo:VO_0004900 a rdfs:Class ; rdfs:label "MERS vaccine"@en ; rdfs:subClassOf obo:VO_0004897 . obo:NCBITaxon_711465 a rdfs:Class ; rdfs:label "Feline coronavirus UU22" ; rdfs:subClassOf obo:NCBITaxon_12663 . obo:PR_000014314 a rdfs:Class ; rdfs:label "U3 small nucleolar RNA-interacting protein 2" ; rdfs:comment "A protein that is a translation product of the human RRP9 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:CHEBI_47278 a rdfs:Class ; rdfs:label "5-BROMOVINYLDEOXYURIDINE" ; rdfs:subClassOf obo:CHEBI_50860 . obo:CHEBI_33233 a rdfs:Class ; rdfs:label "fundamental particle" ; rdfs:comment "A particle not known to have substructure." ; rdfs:subClassOf obo:CHEBI_36342 . obo:NCBITaxon_1868636 a rdfs:Class ; rdfs:label "Bat coronavirus/4292/2013/Desmodus rotundus/Brazil" ; rdfs:subClassOf obo:NCBITaxon_366617 . obo:CHEBI_85282 a rdfs:Class ; rdfs:label "N-(monounsaturated fatty acyl)ethanolamine" ; rdfs:comment "An N-acylethanolamine resulting from the formal condensation of the carboxy group of any monounsaturated fatty acid with the amino group of ethanolamine." ; rdfs:subClassOf obo:CHEBI_167098 , obo:CHEBI_52640 . obo:OBI_0000855 a rdfs:Class ; rdfs:label "total RNA extraction" ; rdfs:comment "A RNA extraction process in which total cellular and organelle RNA are extracted." ; rdfs:subClassOf obo:OBI_0666666 . obo:PR_Q9Y276 a rdfs:Class ; rdfs:label "mitochondrial chaperone BCS1 (human)" ; rdfs:comment "A mitochondrial chaperone BCS1 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000004713 , obo:PR_000029067 . obo:CHEBI_66956 a rdfs:Class ; rdfs:label "antidyskinesia agent" ; rdfs:comment "Any compound which can be used to treat or alleviate the symptoms of dyskinesia." ; rdfs:subClassOf obo:CHEBI_23888 . obo:PR_000000219 a rdfs:Class ; rdfs:label "activin/inhibin beta E chain" ; rdfs:comment "An activin/inhibin beta subunit that is a translation product of the human INHBE gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000072 . obo:PR_Q99996 a rdfs:Class ; rdfs:label "A-kinase anchor protein 9 (human)" ; rdfs:comment "An A-kinase anchor protein 9 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000003896 , obo:PR_000029067 . obo:OBI_0002600 a rdfs:Class ; rdfs:label "collecting specimen with swab" ; rdfs:comment "A specimen collection process that uses a swab as the collection device. A swab is an absorbent material (e.g. cotton) on a rod (e.g., wooden stick)." ; rdfs:subClassOf obo:OBI_0000659 . a rdfs:Class ; rdfs:label "Gynecomastia [Disease/Finding]" ; rdfs:subClassOf . obo:UBERON_0000970 a rdfs:Class ; rdfs:label "eye" ; rdfs:comment "An organ that detects light." ; rdfs:subClassOf obo:UBERON_0000465 . a rdfs:Class ; rdfs:label "Biological Factors [Chemical/Ingredient]" ; rdfs:subClassOf . obo:CHEBI_72600 a rdfs:Class ; rdfs:label "spiroketal" ; rdfs:comment "A cyclic ketal in which the ketal carbon is the only common atom of two rings." ; rdfs:subClassOf obo:CHEBI_37948 , obo:CHEBI_59779 . obo:OPMI_0000562 a rdfs:Class ; rdfs:label "device exposure start date"@en ; rdfs:comment "The date on which a device exposure starts." ; rdfs:subClassOf obo:OPMI_0000556 . obo:CHEBI_37141 a rdfs:Class ; rdfs:label "organobromine compound" ; rdfs:comment "A compound containing at least one carbon-bromine bond." ; rdfs:subClassOf obo:CHEBI_17792 , obo:CHEBI_22928 . obo:PR_000012873 a rdfs:Class ; rdfs:label "serine/threonine-protein kinase PLK4" ; rdfs:comment "A protein that is a translation product of the human PLK4 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:VO_0000610 a rdfs:Class ; rdfs:label "viral vaccine vector" ; rdfs:comment "a vaccine vector that uses a virus as the vector." ; rdfs:subClassOf obo:VO_0000599 . obo:CIDO_0000432 a rdfs:Class ; rdfs:label "COVID-19 immune marker"@en ; rdfs:subClassOf obo:OPMI_0000446 . obo:CHEBI_33663 a rdfs:Class ; rdfs:label "cyclic hydrocarbon" ; rdfs:subClassOf obo:CHEBI_24632 , obo:CHEBI_33598 . obo:CHEBI_33597 a rdfs:Class ; rdfs:label "homocyclic compound" ; rdfs:comment "A cyclic compound having as ring members atoms of the same element only." ; rdfs:subClassOf obo:CHEBI_33595 . obo:CIDO_0000205 a rdfs:Class ; rdfs:label "SARS-CoV-2 RTC formation"@en ; rdfs:subClassOf obo:CIDO_0000190 , obo:CIDO_0000197 . obo:CHEBI_63943 a rdfs:Class ; rdfs:label "22,23-dihydroavermectin B1b" ; rdfs:comment "A macrocyclic lactone that is avermectin B1b in which the double bond present in the spirocyclic ring system has been reduced to a single bond. It is the minor component of ivermectin." ; rdfs:subClassOf obo:CHEBI_63944 , obo:CHEBI_72600 . obo:CHEBI_32727 a rdfs:Class ; rdfs:label "tryptophanate" ; rdfs:comment "An alpha-amino-acid anion that is the conjugate base of tryptophan, arising from deprotonation of the carboxy group." ; rdfs:subClassOf obo:CHEBI_33558 . obo:CIDO_0000163 a rdfs:Class ; rdfs:label "droplet nuclei transmission of SARS-CoV-2"@en ; rdfs:subClassOf obo:CIDO_0000161 . obo:CHEBI_49167 a rdfs:Class ; rdfs:label "anti-asthmatic drug" ; rdfs:comment "A drug used to treat asthma." ; rdfs:subClassOf obo:CHEBI_23888 , obo:CHEBI_65023 . obo:OBI_0000245 a rdfs:Class ; rdfs:label "organization"@en ; rdfs:comment "An entity that can bear roles, has members, and has a set of organization rules. Members of organizations are either organizations themselves or individual people. Members can bear specific organization member roles that are determined in the organization rules. The organization rules also determine how decisions are made on behalf of the organization by the organization members."@en ; rdfs:subClassOf obo:BFO_0000040 . obo:CHEBI_35222 a rdfs:Class ; rdfs:label "inhibitor" ; rdfs:comment "A substance that diminishes the rate of a chemical reaction." ; rdfs:subClassOf obo:CHEBI_24432 . obo:PR_P21918 a rdfs:Class ; rdfs:label "D(1B) dopamine receptor (human)" ; rdfs:comment "A D(1B) dopamine receptor that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000001176 , obo:PR_000029067 . obo:HP_0002910 a rdfs:Class ; rdfs:label "Elevated hepatic transaminase" ; rdfs:comment "Elevations of the levels of SGOT and SGPT in the serum. SGOT (serum glutamic oxaloacetic transaminase) and SGPT (serum glutamic pyruvic transaminase) are transaminases primarily found in the liver and heart and are released into the bloodstream as the result of liver or heart damage. SGOT and SGPT are used clinically mainly as markers of liver damage." ; rdfs:subClassOf obo:HP_0001939 . a rdfs:Class ; rdfs:label "Bepridil [Chemical/Ingredient]" ; rdfs:subClassOf . obo:DRON_00021964 a rdfs:Class ; rdfs:label "Fluphenazine / Nortriptyline Oral Tablet" ; rdfs:subClassOf obo:DRON_00000022 . obo:GO_1901361 a rdfs:Class ; rdfs:label "organic cyclic compound catabolic process" ; rdfs:comment "The chemical reactions and pathways resulting in the breakdown of organic cyclic compound." ; rdfs:subClassOf obo:GO_1901360 , obo:GO_1901575 . obo:CIDO_0000656 a rdfs:Class ; rdfs:label "Y73C in SARS-CoV-2 NS8 protein" ; rdfs:comment "An AA mutation or AA variant that has mutated an amino acid at position 73 into a cysteine in ns8." ; rdfs:subClassOf obo:CIDO_0000617 . obo:GO_0071704 a rdfs:Class ; rdfs:label "organic substance metabolic process" ; rdfs:comment "The chemical reactions and pathways involving an organic substance, any molecular entity containing carbon." ; rdfs:subClassOf obo:GO_0008152 . obo:OBI_0000849 a rdfs:Class ; rdfs:label "organellar RNA extraction" ; rdfs:comment "A RNA extraction process in which the desired output material is RNA in the organelle(s)." ; rdfs:subClassOf obo:OBI_0666666 . obo:CIDO_0000338 a rdfs:Class ; rdfs:label "GAISSVLNDILSRLD"@en ; rdfs:subClassOf obo:CIDO_0000314 . a rdfs:Class ; rdfs:label "Mental Disorders [Disease/Finding]" ; rdfs:subClassOf . obo:CHEBI_37022 a rdfs:Class ; rdfs:label "amino-acid anion" ; rdfs:subClassOf obo:CHEBI_29067 , obo:CHEBI_35352 . obo:GO_0009058 a rdfs:Class ; rdfs:label "biosynthetic process" ; rdfs:comment "The chemical reactions and pathways resulting in the formation of substances; typically the energy-requiring part of metabolism in which simpler substances are transformed into more complex ones." ; rdfs:subClassOf obo:GO_0008152 . a rdfs:Class ; rdfs:label "Metabolism [PK]" ; rdfs:subClassOf . obo:NCBITaxon_89593 a rdfs:Class ; rdfs:label "Craniata " ; rdfs:subClassOf obo:NCBITaxon_7711 . a rdfs:Class ; rdfs:label "Decreased Hematopoiesis [PE]" ; rdfs:subClassOf . obo:CHEBI_42219 a rdfs:Class ; rdfs:label "digitoxigenin" ; rdfs:comment "A 5beta-cardenolide that is 5beta-cardanolide with hydroxy substituents at the 3beta- and 14beta-positions and double bond unsaturation at C(20)-C(22)." ; rdfs:subClassOf obo:CHEBI_36836 , obo:CHEBI_36862 . obo:CIDO_0000551 a rdfs:Class ; rdfs:label "SVKSYDSLVYTGVLG" ; rdfs:comment "A coronavirus epitope that is part of some S protein from HCoV OC43 composed of the following amino acids SVKSYDSLVYTGVLG" ; rdfs:subClassOf obo:CIDO_0000452 . a rdfs:Class ; rdfs:label "Nervous System Neoplasms [Disease/Finding]" ; rdfs:subClassOf , . obo:DOID_936 a rdfs:Class ; rdfs:label "brain disease" ; rdfs:comment "A central nervous system disease that is located_in the brain." ; rdfs:subClassOf obo:DOID_331 . obo:NCBITaxon_264990 a rdfs:Class ; rdfs:label "SARS coronavirus sf098" ; rdfs:subClassOf obo:NCBITaxon_694009 . obo:NCBITaxon_875612 a rdfs:Class ; rdfs:label "Bat coronavirus HKU9-10-1" ; rdfs:subClassOf obo:NCBITaxon_694006 . obo:NCBITaxon_2586419 a rdfs:Class ; rdfs:label "Rhinolophus bat coronavirus HKU32" ; rdfs:subClassOf obo:NCBITaxon_2691596 . obo:NCBITaxon_344702 a rdfs:Class ; rdfs:label "SARS coronavirus ZJ0301" ; rdfs:subClassOf obo:NCBITaxon_694009 . obo:VO_0001237 a rdfs:Class ; rdfs:label "CpG DNA vaccine adjuvant" ; rdfs:comment "A microbial derivative vaccine adjuvant compsed of CpG DNA." ; rdfs:subClassOf obo:VO_0000118 . obo:CHEBI_57694 a rdfs:Class ; rdfs:label "quercetin-7-olate" ; rdfs:comment "Conjugate base of quercetin arising from selective deprotonation of the 7-hydroxy group; major species at pH 7.3." ; rdfs:subClassOf obo:CHEBI_58588 . obo:PR_000011145 a rdfs:Class ; rdfs:label "sialidase-1" ; rdfs:comment "A vertebrate-like neuraminidase that is a translation product of the human NEU1 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000022007 . obo:PR_Q99959 a rdfs:Class ; rdfs:label "plakophilin-2 (human)" ; rdfs:comment "A plakophilin-2 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000012791 , obo:PR_000029067 . a rdfs:Class ; rdfs:label "Papillomavirus Infections [Disease/Finding]" ; rdfs:subClassOf , . obo:OPMI_0004480 a rdfs:Class ; rdfs:label "study participant's family member role"@en ; rdfs:comment "A role of a person who is a family member of a participant in an investigation study." ; rdfs:subClassOf obo:OMRSE_00000024 . obo:CIDO_0020081 a rdfs:Class ; rdfs:label "cobas SARS-CoV-2" ; rdfs:seeAlso ; rdfs:subClassOf obo:CIDO_0000454 . obo:HP_0011692 a rdfs:Class ; rdfs:label "Supraventricular tachycardia with a concealed accessory pathway on the right free wall" ; rdfs:subClassOf obo:HP_0011689 . a rdfs:Class ; rdfs:label "Endocrine Activity Alteration [PE]" ; rdfs:subClassOf . obo:GO_0015850 a rdfs:Class ; rdfs:label "organic hydroxy compound transport" ; rdfs:comment "The directed movement of an organic hydroxy compound (organic alcohol) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. An organic hydroxy compound is an organic compound having at least one hydroxy group attached to a carbon atom." ; rdfs:subClassOf obo:GO_0071702 . obo:HP_0011458 a rdfs:Class ; rdfs:label "Abdominal symptom" ; rdfs:comment "A subjective manifestation of disease localized to the abdomen." ; rdfs:subClassOf obo:HP_0025032 . obo:NCBITaxon_2520501 a rdfs:Class ; rdfs:label "Alphacoronavirus L232" ; rdfs:subClassOf obo:NCBITaxon_2724758 . obo:CIDO_0000372 a rdfs:Class ; rdfs:label "protective mask"@en ; rdfs:comment "A kit or equipment worn on the head and face to afford protection to the wearer" ; rdfs:subClassOf obo:CIDO_0000365 . a rdfs:Class ; rdfs:label "Brain Neoplasms [Disease/Finding]" ; rdfs:subClassOf , . obo:CHEBI_36342 a rdfs:Class ; rdfs:label "subatomic particle" ; rdfs:comment "A particle smaller than an atom." ; rdfs:subClassOf obo:BFO_0000040 . obo:CIDO_0000951 a rdfs:Class ; rdfs:label "SARS-CoV2 nsp9 protein binding to human FBN2" ; rdfs:comment "SARS-CoV2 nsp9 protein binding to human FBN2, as evidented by an affinity-purification mass spectrometry experiment" ; rdfs:subClassOf obo:CIDO_0000583 . obo:NCBITaxon_1487703 a rdfs:Class ; rdfs:label "Rhinolophus affinis coronavirus" ; rdfs:subClassOf obo:NCBITaxon_694009 . obo:NCBITaxon_1699321 a rdfs:Class ; rdfs:label "Myotis Bat Alphacoronavirus strain YNXY_10C" ; rdfs:subClassOf obo:NCBITaxon_366617 . obo:NCBITaxon_681871 a rdfs:Class ; rdfs:label "Kenya bat coronavirus BtKY25" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:CHEBI_33822 a rdfs:Class ; rdfs:label "organic hydroxy compound" ; rdfs:comment "An organic compound having at least one hydroxy group attached to a carbon atom." ; rdfs:subClassOf obo:CHEBI_24651 , obo:CHEBI_50860 . obo:NCBITaxon_1503301 a rdfs:Class ; rdfs:label "BtRs-BetaCoV/GX2013" ; rdfs:subClassOf obo:NCBITaxon_694009 . obo:NCBITaxon_1225483 a rdfs:Class ; rdfs:label "Bat coronavirus Gabon/292/2009" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:OAE_0000555 a rdfs:Class ; rdfs:label "homeostasis AE" ; rdfs:comment "an AE that occurs in the homeostasis system." ; rdfs:subClassOf obo:OAE_0000001 . a rdfs:Class ; rdfs:label "Conjunctivitis, Allergic [Disease/Finding]" ; rdfs:subClassOf , . obo:NCBITaxon_264386 a rdfs:Class ; rdfs:label "SARS coronavirus TW-YM4" ; rdfs:subClassOf obo:NCBITaxon_264370 . obo:CIDO_0001144 a rdfs:Class ; rdfs:label "SARS-CoV-2 S protein amino acid deletion"@en ; rdfs:comment "A SARS-CoV-2 protein AA deletion that affected a SARS-CoV-2 S protein." ; rdfs:subClassOf obo:CIDO_0000614 . obo:CHEBI_64416 a rdfs:Class ; rdfs:label "EC 1.3.1.43 (arogenate dehydrogenase) inhibitor" ; rdfs:comment "An EC 1.3.1.* (oxidoreductase acting on CH-CH group of donor, NAD(+) or NADP(+) as acceptor) inhibitor that interferes with the action of arogenate dehydrogenase (EC 1.3.1.43)." ; rdfs:subClassOf obo:CHEBI_76857 . obo:CHEBI_35237 a rdfs:Class ; rdfs:label "cysteine zwitterion" ; rdfs:subClassOf obo:CHEBI_35238 . obo:CIDO_0000711 a rdfs:Class ; rdfs:label "L1203F in SARS-CoV-2 pp1b protein"@en ; rdfs:comment "An AA mutation or AA variant that has mutated an amino acid at position 314 into a phenylalanine in pp1b." ; rdfs:subClassOf obo:CIDO_0001084 . obo:CHEBI_83157 a rdfs:Class ; rdfs:label "EC 6.2.1.3 (long-chain-fatty-acid--CoA ligase) inhibitor" ; rdfs:comment "An EC 6.2.1.* (acid-thiol ligase) inhibitor that interferes with the action of a long-chain-fatty-acid--CoA ligase (EC 6.2.1.3)." ; rdfs:subClassOf obo:CHEBI_83156 . obo:CHEBI_22479 a rdfs:Class ; rdfs:label "amino cyclitol glycoside" ; rdfs:subClassOf obo:CHEBI_23451 , obo:CHEBI_24400 . obo:GO_0014072 a rdfs:Class ; rdfs:label "response to isoquinoline alkaloid" ; rdfs:comment "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an isoquinoline alkaloid stimulus. An isoquinoline alkaloid is any member of a group of compounds with the heterocyclic ring structure of benzo(c)pyridine which is a structure characteristic of the group of opium alkaloids." ; rdfs:subClassOf obo:GO_0014070 , obo:GO_0043279 . obo:PR_Q05397 a rdfs:Class ; rdfs:label "focal adhesion kinase 1 (human)" ; rdfs:comment "A focal adhesion kinase 1 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000003031 , obo:PR_000029067 . obo:VO_0005339 a rdfs:Class ; rdfs:label "Ad5-triCoV/Mac"@en ; rdfs:comment "A SARS-CoV-2 replication deficient human adenovirus vector vaccine expressing the spike, nucleocapsid and RNA polymerase proteins." ; rdfs:subClassOf obo:VO_0005200 . a rdfs:Class ; rdfs:label "Rheumatic Diseases [Disease/Finding]" ; rdfs:subClassOf , . obo:CIDO_0000662 a rdfs:Class ; rdfs:label "D215G in SARS-CoV-2 S protein" ; rdfs:comment "An AA mutation or AA variant that has mutated an amino acid at position 215 into a glycine in S protein." ; rdfs:subClassOf obo:CIDO_0000594 . a rdfs:Class ; rdfs:label "Pneumonia [Disease/Finding]" ; rdfs:subClassOf , . obo:CHEBI_33308 a rdfs:Class ; rdfs:label "carboxylic ester" ; rdfs:comment "An ester of a carboxylic acid, R(1)C(=O)OR(2), where R(1) = H or organyl and R(2) = organyl." ; rdfs:subClassOf obo:CHEBI_35701 , obo:CHEBI_36586 . obo:CHEBI_48590 a rdfs:Class ; rdfs:label "hydroxypiperidine" ; rdfs:subClassOf obo:CHEBI_26151 . obo:CIDO_0000599 a rdfs:Class ; rdfs:label "SARS-CoV2 E protein binding to human AP3B1" ; rdfs:comment "SARS-CoV2 E protein binding to human AP3B1, as evidented by an affinity-purification mass spectrometry experiment" ; rdfs:subClassOf obo:CIDO_0000046 . obo:VO_0002993 a rdfs:Class ; rdfs:label "SARS-CoV E gene mutant vaccine" ; rdfs:comment "An E mutant is attenuated in hamsters and induces significant protection from challenge with wild type SARS" ; rdfs:subClassOf obo:VO_0012183 . obo:OGG_3043740575 a rdfs:Class ; rdfs:label "N gene of severe acute respiratory syndrome coronavirus 2" ; rdfs:subClassOf obo:OGG_2002697049 . obo:PR_P37173 a rdfs:Class ; rdfs:label "TGF-beta receptor type-2 (human)" ; rdfs:comment "A TGF-beta receptor type-2 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000000005 , obo:PR_000029067 . obo:PR_000012204 a rdfs:Class ; rdfs:label "polyadenylate-binding protein 1" ; rdfs:comment "A protein that is a translation product of the human PABPC1 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:UBERON_0002367 a rdfs:Class ; rdfs:label "prostate gland" ; rdfs:comment "The prostate gland is a partly muscular, partly glandular body that is situated near the base of the mammalian male urethra and secretes an alkaline viscid fluid which is a major constituent of the ejaculatory fluid." ; rdfs:subClassOf obo:UBERON_0000465 . obo:GO_0009636 a rdfs:Class ; rdfs:label "response to toxic substance" ; rdfs:comment "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a toxic stimulus." ; rdfs:subClassOf obo:GO_0042221 . obo:CIDO_0000013 a rdfs:Class ; rdfs:label "COVID-19 experimental drug role"@en ; rdfs:comment "A drug role that is realized in the treatment for COVID-19 disease at the experimental level." ; rdfs:subClassOf obo:CIDO_0000011 . a rdfs:Class ; rdfs:label "Tumor Virus Infections [Disease/Finding]" ; rdfs:subClassOf , obo:DOID_934 . obo:PR_O75347 a rdfs:Class ; rdfs:label "tubulin-specific chaperone A (human)" ; rdfs:comment "A tubulin-specific chaperone A that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000016125 , obo:PR_000029067 . obo:CHEBI_38260 a rdfs:Class ; rdfs:label "pyrrolidines" ; rdfs:comment "Any of a class of heterocyclic amines having a saturated five-membered ring." ; rdfs:subClassOf obo:CHEBI_25693 , obo:CHEBI_38101 . obo:GO_0030155 a rdfs:Class ; rdfs:label "regulation of cell adhesion" ; rdfs:comment "Any process that modulates the frequency, rate or extent of attachment of a cell to another cell or to the extracellular matrix." ; rdfs:subClassOf obo:GO_0050794 . obo:CHEBI_22743 a rdfs:Class ; rdfs:label "benzyl alcohols" ; rdfs:comment "Compounds containing a phenylmethanol skeleton." ; rdfs:subClassOf obo:CHEBI_33854 . obo:CHEBI_35475 a rdfs:Class ; rdfs:label "non-steroidal anti-inflammatory drug" ; rdfs:comment "An anti-inflammatory drug that is not a steroid. In addition to anti-inflammatory actions, non-steroidal anti-inflammatory drugs have analgesic, antipyretic, and platelet-inhibitory actions. They act by blocking the synthesis of prostaglandins by inhibiting cyclooxygenase, which converts arachidonic acid to cyclic endoperoxides, precursors of prostaglandins." ; rdfs:subClassOf obo:CHEBI_35472 , obo:CHEBI_35842 . obo:PR_000001041 a rdfs:Class ; rdfs:label "Na(+)/H(+) exchange regulatory cofactor NHE-RF1" ; rdfs:comment "A Na(+)/H(+) exchange regulatory cofactor with ERM-binding domain that is a translation product of the human SLC9A3R1 gene or a 1:1 ortholog thereof. It contains two copies of the PDZ domain at the N terminus and an EBP50 domain at the C-terminus. The latter allows interaction with FERM domains, resulting in the activation of ERM proteins (PR:000001030), with subsequent cytoskeletal modulation and cellular growth control." ; rdfs:subClassOf obo:PR_000001043 . obo:CHEBI_36233 a rdfs:Class ; rdfs:label "disaccharide" ; rdfs:comment "A compound in which two monosaccharides are joined by a glycosidic bond." ; rdfs:subClassOf obo:CHEBI_50699 . obo:NCBITaxon_461306 a rdfs:Class ; rdfs:label "Rocky Mountain Bat Coronavirus 3" ; rdfs:subClassOf obo:NCBITaxon_366617 . obo:PR_000008979 a rdfs:Class ; rdfs:label "interleukin-10 receptor subunit beta" ; rdfs:comment "A protein that is a translation product of the human IL10RB gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:PR_P01375 a rdfs:Class ; rdfs:label "tumor necrosis factor (human)" ; rdfs:comment "A tumor necrosis factor that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000000134 , obo:PR_000029067 . obo:PR_000017078 a rdfs:Class ; rdfs:label "serine/threonine-protein kinase ULK2" ; rdfs:comment "A protein that is a translation product of the human ULK2 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . a rdfs:Class ; rdfs:label "Oxyuriasis [Disease/Finding]" ; rdfs:subClassOf . obo:HP_0004430 a rdfs:Class ; rdfs:label "Severe combined immunodeficiency" ; rdfs:comment "A combined immunodeficiency primary immune deficiency that is characterized by a more severe defect in both the T- and B-lymphocyte systems." ; rdfs:subClassOf obo:HP_0010978 . obo:CIDO_0001122 a rdfs:Class ; rdfs:label "SARS-CoV2 orf8 protein binding to human NGLY1"@en ; rdfs:comment "SARS-CoV2 orf8 protein binding to human NGLY1, as evidented by an affinity-purification mass spectrometry experiment" ; rdfs:subClassOf obo:CIDO_0000051 . obo:CHEBI_77402 a rdfs:Class ; rdfs:label "EC 1.8.1.12 (trypanothione-disulfide reductase) inhibitor" ; rdfs:comment "An EC 1.8.1.* (oxidoreductase acting on sulfur group of donors, NAD+ or NADP+ as acceptor) inhibitor that interferes with the action of trypanothione-disulfide reductase (EC 1.8.1.12)." ; rdfs:subClassOf obo:CHEBI_76869 . a rdfs:Class ; rdfs:label "Substance-Related Disorders [Disease/Finding]" ; rdfs:subClassOf . obo:OBI_0000444 a rdfs:Class ; rdfs:label "target of material addition role"@en ; rdfs:comment "target of material addition role is a role realized by an entity into which a material is added in a material addition process" ; rdfs:subClassOf obo:BFO_0000023 . obo:CHEBI_32661 a rdfs:Class ; rdfs:label "asparaginium" ; rdfs:subClassOf obo:CHEBI_33719 . obo:NCBITaxon_1269313 a rdfs:Class ; rdfs:label "Coronavirus BtCoV/KP524/Art_jam/PAN/2010" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:CHEBI_15377 a rdfs:Class ; rdfs:label "water" ; rdfs:comment "An oxygen hydride consisting of an oxygen atom that is covalently bonded to two hydrogen atoms." ; rdfs:subClassOf obo:CHEBI_33693 , obo:CHEBI_37176 , obo:CHEBI_52625 . obo:PR_Q9UKI8 a rdfs:Class ; rdfs:label "serine/threonine-protein kinase tousled-like 1 (human)" ; rdfs:comment "A serine/threonine-protein kinase tousled-like 1 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000016377 , obo:PR_000029067 . obo:CIDO_0000622 a rdfs:Class ; rdfs:label "A63T in SARS-CoV-2 M protein" ; rdfs:comment "An AA mutation or AA variant that has mutated an amino acid at position 63 into a threonine in M protein." ; rdfs:subClassOf obo:CIDO_0000619 . obo:NCBITaxon_1511620 a rdfs:Class ; rdfs:label "Coronavirus BtCoV/B85/HUN/2013" ; rdfs:subClassOf obo:NCBITaxon_2664420 . a rdfs:Class ; rdfs:label "Blast Crisis [Disease/Finding]" ; rdfs:subClassOf , . a rdfs:Class ; rdfs:label "Decreased Capillary Permeability [PE]" ; rdfs:subClassOf . obo:GO_0015075 a rdfs:Class ; rdfs:label "ion transmembrane transporter activity" ; rdfs:comment "Enables the transfer of an ion from one side of a membrane to the other." ; rdfs:subClassOf obo:GO_0022857 . obo:CHEBI_26287 a rdfs:Class ; rdfs:label "propane-1,3-diols" ; rdfs:comment "Any propanediol bearing hydroxy groups at positions 1 and 3." ; rdfs:subClassOf obo:CHEBI_26288 . obo:NCBITaxon_1261613 a rdfs:Class ; rdfs:label "Neoromicia bat coronavirus/South Africa/167/2007" ; rdfs:subClassOf obo:NCBITaxon_2664420 . a rdfs:Class ; rdfs:label "Decreased Central Nervous System Dopamine Activity [PE]" ; rdfs:subClassOf . obo:CIDO_0000297 a rdfs:Class ; rdfs:label "asymptomatic human female infected by SARS-CoV-2"@en ; rdfs:subClassOf obo:CIDO_0000296 . obo:PR_000008801 a rdfs:Class ; rdfs:label "endoplasmin" ; rdfs:comment "An HSPC protein that is a translation product of the human HSP90B1 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000025350 . obo:PR_000017045 a rdfs:Class ; rdfs:label "UDP-glucose:glycoprotein glucosyltransferase 2" ; rdfs:comment "A protein that is a translation product of the human UGGT2 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:CIDO_0000893 a rdfs:Class ; rdfs:label "SARS-CoV2 nsp7 protein binding to human COMT" ; rdfs:comment "SARS-CoV2 nsp7 protein binding to human COMT, as evidented by an affinity-purification mass spectrometry experiment" ; rdfs:subClassOf obo:CIDO_0000049 . obo:PR_P13569 a rdfs:Class ; rdfs:label "cystic fibrosis transmembrane conductance regulator (human)" ; rdfs:comment "A cystic fibrosis transmembrane conductance regulator that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000001044 , obo:PR_000029067 . obo:PR_Q9BQE4 a rdfs:Class ; rdfs:label "selenoprotein S (human)" ; rdfs:comment "A selenoprotein S that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000014612 , obo:PR_000029067 . obo:IAO_0000003 a rdfs:Class ; rdfs:label "measurement unit label"@en ; rdfs:comment "A data item label that denotes a unit of measure."@en ; rdfs:subClassOf obo:IAO_0000009 , obo:IAO_0000030 . obo:NCBITaxon_2501928 a rdfs:Class ; rdfs:label "Nyctalus velutinus alphacoronavirus SC-2013" ; rdfs:subClassOf obo:NCBITaxon_2509503 . obo:NCBITaxon_1699338 a rdfs:Class ; rdfs:label "Myotis Bat Alphacoronavirus strain YNXY_42C" ; rdfs:subClassOf obo:NCBITaxon_366617 . obo:CIDO_0000274 a rdfs:Class ; rdfs:label "H69- in SARS-CoV-2 S protein"@en ; rdfs:subClassOf obo:CIDO_0001146 . obo:PR_000014219 a rdfs:Class ; rdfs:label "60S ribosomal protein L36" ; rdfs:comment "A protein that is a translation product of the human RPL36 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:PR_O95382 a rdfs:Class ; rdfs:label "mitogen-activated protein kinase kinase kinase 6 (human)" ; rdfs:comment "A mitogen-activated protein kinase kinase kinase 6 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000010139 , obo:PR_000029067 . obo:CIDO_0000107 a rdfs:Class ; rdfs:label "interruption to SARS-CoV-2 replication in host cell"@en ; rdfs:comment "A process that interrupts SARS-CoV-2 virus entry to host cell" ; rdfs:subClassOf obo:CIDO_0000103 . obo:PR_Q96SN8 a rdfs:Class ; rdfs:label "CDK5 regulatory subunit-associated protein 2 (human)" ; rdfs:comment "A CDK5 regulatory subunit-associated protein 2 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000005262 , obo:PR_000029067 . obo:PR_000003601 a rdfs:Class ; rdfs:label "medium-chain specific acyl-CoA dehydrogenase, mitochondrial" ; rdfs:comment "A protein that is a translation product of the human ACADM gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:NCBITaxon_681860 a rdfs:Class ; rdfs:label "Kenya bat coronavirus BtKY13" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:CHEBI_32650 a rdfs:Class ; rdfs:label "L-asparaginate" ; rdfs:comment "An optically active form of asparaginate having L-configuration." ; rdfs:subClassOf obo:CHEBI_32660 , obo:CHEBI_59814 . obo:OAE_0000945 a rdfs:Class ; rdfs:label "feeling abnormal AE" ; rdfs:comment "a sensory capabilty AE that results in the patient feeling different than normal after a medical intervention such as taking drug" ; rdfs:subClassOf obo:OAE_0000582 . obo:PR_P53779 a rdfs:Class ; rdfs:label "mitogen-activated protein kinase 10 (human)" ; rdfs:comment "A mitogen-activated protein kinase 10 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000010151 , obo:PR_000029067 . obo:CHEBI_189658 a rdfs:Class ; rdfs:label "4EGI-1" ; rdfs:subClassOf obo:CHEBI_23697 , obo:CHEBI_25384 , obo:CHEBI_35716 , obo:CHEBI_38418 , obo:CHEBI_38532 . obo:PR_000014190 a rdfs:Class ; rdfs:label "60S ribosomal protein L11" ; rdfs:comment "A protein that is a translation product of the human RPL11 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:VO_0005411 a rdfs:Class ; rdfs:label "UNAIR Inactivated COVID-19 Vaccine"@en ; rdfs:comment "A SARS-CoV-2 inactivated vaccine developed by Airlangga University" ; rdfs:subClassOf obo:VO_0005201 . obo:CHEBI_50646 a rdfs:Class ; rdfs:label "bone density conservation agent" ; rdfs:comment "An agent that inhibits bone resorption and/or favor bone mineralization and bone regeneration. Used to heal bone fractures and to treat bone diseases such as osteopenia and osteoporosis." ; rdfs:subClassOf obo:CHEBI_23888 . obo:CIDO_0000159 a rdfs:Class ; rdfs:label "fomite transmission of SARS-CoV-2"@en ; rdfs:subClassOf obo:CIDO_0000156 . obo:PR_P31152 a rdfs:Class ; rdfs:label "mitogen-activated protein kinase 4 (human)" ; rdfs:comment "A mitogen-activated protein kinase 4 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000010157 , obo:PR_000029067 . obo:CIDO_0001043 a rdfs:Class ; rdfs:label "SARS-CoV2 orf9b protein binding to human TOMM70" ; rdfs:comment "SARS-CoV2 orf9b protein binding to human TOMM70, as evidented by an affinity-purification mass spectrometry experiment" ; rdfs:subClassOf obo:CIDO_0000052 . a rdfs:Class ; rdfs:label "Hypothalamic Endocrine Activity Alteration [PE]" ; rdfs:subClassOf . obo:NCBITaxon_864605 a rdfs:Class ; rdfs:label "Bat coronavirus BM98-13/BGR/2008" ; rdfs:subClassOf obo:NCBITaxon_2664420 . a rdfs:Class ; rdfs:label "Cinanserin [Chemical/Ingredient]" ; rdfs:subClassOf . obo:PR_000013485 a rdfs:Class ; rdfs:label "6-pyruvoyl tetrahydrobiopterin synthase" ; rdfs:comment "A protein that is a translation product of the human PTS gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:DOID_5419 a rdfs:Class ; rdfs:label "schizophrenia" ; rdfs:comment "A psychotic disorder that is characterized by a disintegration of thought processes and of emotional responsiveness." ; rdfs:subClassOf obo:DOID_2468 . obo:NCBITaxon_293935 a rdfs:Class ; rdfs:label "SARS coronavirus PC4-136" ; rdfs:subClassOf obo:NCBITaxon_694009 . obo:OGG_2000002759 a rdfs:Class ; rdfs:label "gene of Eukaryota" ; rdfs:comment "A gene of an organism of Eukaryota" ; rdfs:subClassOf obo:OGG_0000000002 . obo:NCBITaxon_1232736 a rdfs:Class ; rdfs:label "unclassified Deltacoronavirus" ; rdfs:subClassOf obo:NCBITaxon_1159901 . a rdfs:Class ; rdfs:label "Pathological Conditions, Signs and Symptoms [Disease/Finding]" ; rdfs:subClassOf . a rdfs:Class ; rdfs:label "Lip Diseases [Disease/Finding]" ; rdfs:subClassOf . obo:CHEBI_36043 a rdfs:Class ; rdfs:label "antimicrobial drug" ; rdfs:comment "A drug used to treat or prevent microbial infections." ; rdfs:subClassOf obo:CHEBI_33281 , obo:CHEBI_35441 . obo:OBI_0302886 a rdfs:Class ; rdfs:label "centrifugation"@en ; rdfs:comment "centrifugation is a process separating molecules by size or density using centrifugal forces generated by a spinning rotor. G-forces of several hundred thousand times gravity are generated in ultracentrifugation"@en ; rdfs:subClassOf obo:OBI_0600014 . obo:OPMI_0000531 a rdfs:Class ; rdfs:label "condition start date"@en ; rdfs:comment "The date on which a condition starts." ; rdfs:subClassOf obo:OPMI_0000528 . obo:GO_0006955 a rdfs:Class ; rdfs:label "immune response" ; rdfs:comment "Any immune system process that functions in the calibrated response of an organism to a potential internal or invasive threat." ; rdfs:subClassOf obo:BFO_0000015 , obo:GO_0002376 , obo:GO_0050896 . obo:PR_000015518 a rdfs:Class ; rdfs:label "spartin" ; rdfs:comment "A protein that is a translation product of the human SPART gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:CHEBI_26410 a rdfs:Class ; rdfs:label "pyrazoles" ; rdfs:subClassOf obo:CHEBI_23677 . obo:CHEBI_51915 a rdfs:Class ; rdfs:label "indolocarbazole" ; rdfs:comment "Compounds based upon an indolo[2,3-a]carbazole skeleton." ; rdfs:subClassOf obo:CHEBI_38166 . obo:VO_0005257 a rdfs:Class ; rdfs:label "COVID-19 inactivated vaccine by the Scientific and Technological Research Council of Turkey"@en ; rdfs:comment "A SARS-CoV-2 inactivated virus vaccine by the Scientific and Technological Research Council of Turkey adjuvanted by aluminum hydroxide and CpG ODN" ; rdfs:subClassOf obo:VO_0005201 . obo:DOID_0070089 a rdfs:Class ; rdfs:label "schizophrenia 13" ; rdfs:comment "A schizophrenia that has_material_basis_in a mutation on chromosome 15q13." ; rdfs:subClassOf obo:DOID_0050177 , obo:DOID_5419 . obo:CIDO_0020169 a rdfs:Class ; rdfs:label "IAMP COVID-19 DETECTION KIT" ; rdfs:seeAlso ; rdfs:subClassOf obo:CIDO_0000454 . obo:CIDO_0020182 a rdfs:Class ; rdfs:label "LabGun COVID-19 RT-PCR Kit" ; rdfs:seeAlso ; rdfs:subClassOf obo:CIDO_0000454 . obo:CHEBI_63510 a rdfs:Class ; rdfs:label "EC 3.6.3.9 (Na(+)/K(+)-transporting ATPase) inhibitor" ; rdfs:comment "An EC 3.6.3.* (acid anhydride hydrolase catalysing transmembrane movement of substances) inhibitor that interferes with the action of Na(+)/K(+)-transporting ATPase (EC 3.6.3.9)." ; rdfs:subClassOf obo:CHEBI_76895 . obo:PR_000014566 a rdfs:Class ; rdfs:label "succinate dehydrogenase [ubiquinone] cytochrome b small subunit, mitochondrial" ; rdfs:comment "A protein that is a translation product of the human SDHD gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:CHEBI_48376 a rdfs:Class ; rdfs:label "carbamimidic acid" ; rdfs:subClassOf obo:CHEBI_48379 , obo:CHEBI_64708 . obo:NCBITaxon_11133 a rdfs:Class ; rdfs:label "Bovine coronavirus strain Quebec" ; rdfs:subClassOf obo:NCBITaxon_11128 . obo:CHEBI_59740 a rdfs:Class ; rdfs:label "nucleophilic reagent" ; rdfs:comment "A reagent that forms a bond to its reaction partner (the electrophile) by donating both bonding electrons." ; rdfs:subClassOf obo:CHEBI_33893 , obo:CHEBI_39144 . obo:UBERON_0002469 a rdfs:Class ; rdfs:label "esophagus mucosa" ; rdfs:comment "A mucosa that is part of a esophagus [Automatically generated definition]." ; rdfs:subClassOf obo:UBERON_0000465 . obo:OBI_2000011 a rdfs:Class ; rdfs:label "meconium specimen" ; rdfs:comment "A specimen that is derived from some meconium " ; rdfs:subClassOf obo:OBI_0002503 . obo:CIDO_0000894 a rdfs:Class ; rdfs:label "SARS-CoV2 nsp7 protein binding to human CYB5B" ; rdfs:comment "SARS-CoV2 nsp7 protein binding to human CYB5B, as evidented by an affinity-purification mass spectrometry experiment" ; rdfs:subClassOf obo:CIDO_0000049 . obo:CIDO_0000090 a rdfs:Class ; rdfs:label "host response to SARS-CoV-2 infection"@en ; rdfs:comment "A coronavirus-host interaction by which the host responds to SARS-CoV-2 viral infection" ; rdfs:subClassOf obo:CIDO_0000087 , obo:CIDO_0000195 . obo:NCBITaxon_2687252 a rdfs:Class ; rdfs:label "Chalinolobus gouldii alphacoronavirus" ; rdfs:subClassOf obo:NCBITaxon_366617 . obo:PR_000013218 a rdfs:Class ; rdfs:label "5'-AMP-activated protein kinase catalytic subunit alpha-1" ; rdfs:comment "A protein that is a translation product of the human PRKAA1 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:PR_000010712 a rdfs:Class ; rdfs:label "mitochondrial carrier homolog 1" ; rdfs:comment "A protein that is a translation product of the human MTCH1 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:OBI_0000914 a rdfs:Class ; rdfs:label "nasopharyngeal aspirate specimen" ; rdfs:comment """A speciemn which derives from nasopharyngeal mucosa after aspiration.""" ; rdfs:subClassOf obo:OBI_0100051 . obo:IAO_0000109 a rdfs:Class ; rdfs:label "measurement datum"@en ; rdfs:comment "A measurement datum is an information content entity that is a recording of the output of a measurement such as produced by a device."@en ; rdfs:subClassOf obo:IAO_0000027 . a rdfs:Class ; rdfs:label "Otorhinolaryngologic Diseases [Disease/Finding]" ; rdfs:subClassOf . obo:CIDO_0000752 a rdfs:Class ; rdfs:label "SARS-CoV2 M protein binding to human ATP6V1A" ; rdfs:comment "SARS-CoV2 M protein binding to human ATP6V1A, as evidented by an affinity-purification mass spectrometry experiment" ; rdfs:subClassOf obo:CIDO_0000055 . obo:CHEBI_132893 a rdfs:Class ; rdfs:label "fangchinoline" ; rdfs:comment "A bisbenzylisoquinoline alkaloid that is (1beta)- berbaman which has been substituted by methyl groups at the 2 and 2' positions, by methoxy groups at the 6, 6', and 12 positions, and by a hydroxy group at position 7. Isolated from Stephania tetrandra, it has been found to possess neuroprotective and anti-tumour activity." ; rdfs:subClassOf obo:CHEBI_133004 , obo:CHEBI_35618 , obo:CHEBI_51026 . obo:CHEBI_59554 a rdfs:Class ; rdfs:label "medium-chain fatty acid" ; rdfs:comment "Any fatty acid with a chain length of between C6 and C12." ; rdfs:subClassOf obo:CHEBI_35366 . obo:NCBITaxon_2709072 a rdfs:Class ; rdfs:label "Bat coronavirus RaTG13" ; rdfs:subClassOf obo:NCBITaxon_694009 . obo:PR_P16233 a rdfs:Class ; rdfs:label "pancreatic triacylglycerol lipase (human)" ; rdfs:comment "A pancreatic triacylglycerol lipase that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000012925 , obo:PR_000029067 . obo:CHEBI_16414 a rdfs:Class ; rdfs:label "L-valine" ; rdfs:comment "The L-enantiomer of valine." ; rdfs:subClassOf obo:CHEBI_15705 , obo:CHEBI_26463 , obo:CHEBI_27266 , obo:CHEBI_83813 . obo:CIDO_0000306 a rdfs:Class ; rdfs:label "HCoV 229E epitope"@en ; rdfs:subClassOf obo:CIDO_0000300 . obo:NCBITaxon_572287 a rdfs:Class ; rdfs:label "Bulbul coronavirus HKU11-796" ; rdfs:subClassOf obo:NCBITaxon_574549 . a rdfs:Class ; rdfs:label "Epilepsy [Disease/Finding]" ; rdfs:subClassOf . obo:NCBITaxon_906884 a rdfs:Class ; rdfs:label "Feline coronavirus UU19" ; rdfs:subClassOf obo:NCBITaxon_12663 . obo:CIDO_0000066 a rdfs:Class ; rdfs:label "chemical role against viral infection"@en ; rdfs:comment "A role of a chemical effective against viral infection" ; rdfs:subClassOf obo:CHEBI_51086 . obo:GO_0045834 a rdfs:Class ; rdfs:label "positive regulation of lipid metabolic process" ; rdfs:comment "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving lipids." ; rdfs:subClassOf obo:GO_0009893 , obo:GO_0019216 . obo:NCBITaxon_338152 a rdfs:Class ; rdfs:label "Felinae" ; rdfs:subClassOf obo:NCBITaxon_9681 . obo:DOID_14320 a rdfs:Class ; rdfs:label "generalized anxiety disorder" ; rdfs:comment "An anxiety disorder that is characterized by long-lasting anxiety that is not focused on any one object or situation." ; rdfs:subClassOf obo:DOID_2030 . obo:NCBITaxon_1881051 a rdfs:Class ; rdfs:label "Scotophilus kuhlii coronavirus" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:VO_0005241 a rdfs:Class ; rdfs:label "MRT5500"@en ; rdfs:comment "A SARS-CoV-2 mRNA vaccine that is manufactured by Sanofi Pasteur" ; rdfs:subClassOf obo:VO_0005198 . obo:APOLLO_SV_00000442 a rdfs:Class ; rdfs:label "migration speed"@en ; rdfs:comment "A rate measurement datum of that divides the total distance traveled during some migration process by the duration of the temporal interval occupied by that process."@en ; rdfs:subClassOf obo:OBI_0001554 . obo:PR_000006025 a rdfs:Class ; rdfs:label "cathepsin D" ; rdfs:comment "A cathepsin-like protease that is a translation product of the human CTSD gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000040662 . obo:PR_Q9Y673 a rdfs:Class ; rdfs:label "dolichyl-phosphate beta-glucosyltransferase (human)" ; rdfs:comment "A dolichyl-phosphate beta-glucosyltransferase that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000003945 , obo:PR_000029067 . obo:VO_0005149 a rdfs:Class ; rdfs:label "rDNA-expressed S SARS protein vaccine" ; rdfs:comment "A SARS DNA vaccine made from rDNA-expressed ectodomain of the S protein." ; rdfs:subClassOf obo:VO_0012183 . obo:PR_P35916 a rdfs:Class ; rdfs:label "vascular endothelial growth factor receptor 3 (human)" ; rdfs:comment "A vascular endothelial growth factor receptor 3 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000007565 , obo:PR_000029067 . obo:CIDO_0000869 a rdfs:Class ; rdfs:label "SARS-CoV2 nsp2 protein binding to human EIF4E2" ; rdfs:comment "SARS-CoV2 nsp2 protein binding to human EIF4E2, as evidented by an affinity-purification mass spectrometry experiment" ; rdfs:subClassOf obo:CIDO_0000580 . obo:NCBITaxon_1503291 a rdfs:Class ; rdfs:label "BtNv-AlphaCoV/SC2013" ; rdfs:subClassOf obo:NCBITaxon_2501928 . a rdfs:Class ; rdfs:label "Chemical Ingredients [Chemical/Ingredient]" ; rdfs:subClassOf obo:BFO_0000040 . obo:NCBITaxon_497944 a rdfs:Class ; rdfs:label "Bat coronavirus P.pyg/Germany/D5.71/2007" ; rdfs:subClassOf obo:NCBITaxon_366617 . obo:CHEBI_27116 a rdfs:Class ; rdfs:label "trihydroxyflavone" ; rdfs:comment "Any hydroxyflavone carrying three hydroxy groups at unspecified positions." ; rdfs:subClassOf obo:CHEBI_24698 . obo:CIDO_0000180 a rdfs:Class ; rdfs:label "COVID-19 treatment"@en ; rdfs:comment "A treatment for the COVID-19 disease" ; rdfs:subClassOf obo:OGMS_0000090 . obo:PR_P31323 a rdfs:Class ; rdfs:label "cAMP-dependent protein kinase type II-beta regulatory subunit (human)" ; rdfs:comment "A cAMP-dependent protein kinase type II-beta regulatory subunit that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000013231 , obo:PR_000029067 . obo:PR_P21397 a rdfs:Class ; rdfs:label "amine oxidase [flavin-containing] A (human)" ; rdfs:comment "An amine oxidase [flavin-containing] A that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000010114 , obo:PR_000029067 . obo:CIDO_0000533 a rdfs:Class ; rdfs:label "ESQGNVVTSVMESQI" ; rdfs:comment "A coronavirus epitope that is part of some S protein from HCoV HKU1 composed of the following amino acids ESQGNVVTSVMESQI" ; rdfs:subClassOf obo:CIDO_0000450 . obo:CHEBI_60598 a rdfs:Class ; rdfs:label "opioid agent" ; rdfs:comment "Any agent that acts on an opioid receptor or affects the life cycle of an opioid transmitter." ; rdfs:subClassOf obo:CHEBI_35942 . obo:CIDO_0001086 a rdfs:Class ; rdfs:label "AA variant in SARS-CoV-2 nsp15 protein"@en ; rdfs:comment "An AA variant in SARS-CoV-2 nsp15 protein. Equivalent to an AA variant in SARS-CoV-2 rep 1ab with an AA position of 6430 - 6775." ; rdfs:subClassOf obo:CIDO_0000715 . obo:CHEBI_24868 a rdfs:Class ; rdfs:label "organic salt" ; rdfs:subClassOf obo:CHEBI_24866 . obo:NCBITaxon_2501960 a rdfs:Class ; rdfs:label "China Rattus coronavirus HKU24" ; rdfs:subClassOf obo:NCBITaxon_2509481 . obo:PR_000013222 a rdfs:Class ; rdfs:label "cAMP-dependent protein kinase catalytic subunit alpha" ; rdfs:comment "A cAMP-dependent protein kinase catalytic subunit that is a translation product of the human PRKACA gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000029188 . a rdfs:Class ; rdfs:label "GEMCITABINE HYDROCHLORIDE" ; rdfs:subClassOf . a rdfs:Class ; rdfs:label "Breast Glandular Development Alteration [PE]" ; rdfs:subClassOf . obo:CIDO_0000050 a rdfs:Class ; rdfs:label "SARS-CoV-2 Orf10 protein interaction with host protein"@en ; rdfs:comment "A molecular interaction that has participant of the SARS-CoV-2 Orf10 protein and a host protein" ; rdfs:subClassOf obo:CIDO_0000348 . obo:CHEBI_173085 a rdfs:Class ; rdfs:label "ferroptosis inducer" ; rdfs:comment "Any substance that induces or promotes ferroptosis (a type of programmed cell death dependent on iron and characterized by the accumulation of lipid peroxides) in organisms." ; rdfs:subClassOf obo:CHEBI_52206 . obo:CHEBI_61655 a rdfs:Class ; rdfs:label "steroid saponin" ; rdfs:comment "Any saponin derived from a hydroxysteroid." ; rdfs:subClassOf obo:CHEBI_26605 , obo:CHEBI_35341 . a rdfs:Class ; rdfs:label "Aminopyridines [Chemical/Ingredient]" ; rdfs:subClassOf , . obo:NCBITaxon_745730 a rdfs:Class ; rdfs:label "Coronavirus M.das/VM34/2006/NLD" ; rdfs:subClassOf obo:NCBITaxon_696098 . obo:CHEBI_33303 a rdfs:Class ; rdfs:label "chalcogen" ; rdfs:comment "Any p-block element belonging to the group 16 family of the periodic table." ; rdfs:subClassOf obo:CHEBI_33560 . obo:CIDO_0020007 a rdfs:Class ; rdfs:label "Acupath COVID-19 Real-Time (RT-PCR) Assay" ; rdfs:seeAlso ; rdfs:subClassOf obo:CIDO_0000454 . obo:GO_0034613 a rdfs:Class ; rdfs:label "cellular protein localization" ; rdfs:comment "Any process in which a protein is transported to, and/or maintained in, a specific location at the level of a cell. Localization at the cellular level encompasses movement within the cell, from within the cell to the cell surface, or from one location to another at the surface of a cell." ; rdfs:subClassOf obo:GO_0008104 , obo:GO_0070727 . obo:PR_000001891 a rdfs:Class ; rdfs:label "ATP-dependent translocase ABCB1" ; rdfs:comment "A protein that is a translation product of the human ABCB1 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:OAE_0000390 a rdfs:Class ; rdfs:label "malaise AE" ; rdfs:comment "a sensory capability AE that has an outcome of malaise" ; rdfs:subClassOf obo:OAE_0000582 . obo:CHEBI_62872 a rdfs:Class ; rdfs:label "EC 1.2.3.1 (aldehyde oxidase) inhibitor" ; rdfs:comment "An EC 1.2.3.* (oxidoreductase acting on donor aldehyde/oxo group with oxygen as acceptor) inhibitor which interferes with the action of aldehyde oxidase (EC 1.2.3.1)." ; rdfs:subClassOf obo:CHEBI_76853 . obo:NCBITaxon_1288691 a rdfs:Class ; rdfs:label "Bat coronavirus POA/2012/144" ; rdfs:subClassOf obo:NCBITaxon_366617 . obo:NCBITaxon_2163884 a rdfs:Class ; rdfs:label "Alphacoronavirus Mink/China/1/2016" ; rdfs:subClassOf obo:NCBITaxon_2727857 . obo:VO_0005268 a rdfs:Class ; rdfs:label "authorized COVID-19 recombinant adenoviral vector vaccine"@en ; rdfs:subClassOf obo:VO_0005200 , obo:VO_0005267 . obo:NCBITaxon_1679888 a rdfs:Class ; rdfs:label "Coronavirus RCoV/D_RMU10_1228/Mus_dom/GER/2010" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:PR_000044664 a rdfs:Class ; rdfs:label "GABA(A) receptor protein" ; rdfs:comment "A ligand-gated ion channel protein that is a translation product of the human GABRA1-6, GABRB1-3, GABRG1-3, GABRD, GABRE, GABRQ, GABRP, or GABRR1-3 genes, 1:1 orthologs thereof, or a semi-ortholog thereof." ; rdfs:subClassOf obo:PR_000044671 . obo:CHEBI_36054 a rdfs:Class ; rdfs:label "benzoate ester" ; rdfs:comment "Esters of benzoic acid or substituted benzoic acids." ; rdfs:subClassOf obo:CHEBI_33308 , obo:CHEBI_62732 . obo:CHEBI_76707 a rdfs:Class ; rdfs:label "EC 6.2.* (C-S bond-forming ligase) inhibitor" ; rdfs:comment "A ligase inhibitor that interferes with the action of a C-S bond-forming ligase (EC 6.2.*.*)." ; rdfs:subClassOf obo:CHEBI_75603 . a rdfs:Class ; rdfs:label "Decreased Uterine Smooth Muscle Contraction or Tone [PE]" ; rdfs:subClassOf . obo:CHEBI_35338 a rdfs:Class ; rdfs:label "amphetamines" ; rdfs:comment "Amines that constitute a class of central nervous system stimulants based on the structure of the parent amphetamine 1-phenylpropan-2-amine." ; rdfs:subClassOf obo:CHEBI_32952 . obo:IDO_0000600 a rdfs:Class ; rdfs:label "release of infectious human pathogen in laboratory"@en ; rdfs:comment "A host exposure to environment with infectious agent where the exposure is accidental; the environment is a laboratory, and the infectious agent is infectious in humans."@en ; rdfs:subClassOf obo:IDO_0000597 . a rdfs:Class ; rdfs:label "Adenine [Chemical/Ingredient]" ; rdfs:subClassOf . obo:CHEBI_76759 a rdfs:Class ; rdfs:label "EC 3.* (hydrolase) inhibitor" ; rdfs:comment "Any enzyme inhibitor that interferes with the action of a hydrolase (EC 3.*.*.*)." ; rdfs:subClassOf obo:CHEBI_23924 . obo:NCBITaxon_903593 a rdfs:Class ; rdfs:label "Kenya bat coronavirus BtKY55" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:CHEBI_35580 a rdfs:Class ; rdfs:label "N-oxide" ; rdfs:subClassOf obo:CHEBI_25741 . obo:PR_000021990 a rdfs:Class ; rdfs:label "dual specificity mitogen-activated protein kinase kinase 3/6" ; rdfs:comment "A protein that is a gene product level of the MAP2K3 or the MAP2K6 gene. Members of this class activate phosphorylation of a threonine and a tyrosine residue in MAP kinase p38 exclusively." ; rdfs:subClassOf obo:PR_000000001 . obo:CHEBI_134179 a rdfs:Class ; rdfs:label "volatile organic compound" ; rdfs:comment "Any organic compound having an initial boiling point less than or equal to 250 degreeC (482 degreeF) measured at a standard atmospheric pressure of 101.3 kPa." ; rdfs:subClassOf obo:CHEBI_72695 . a rdfs:Class ; rdfs:label "Benzene Derivatives [Chemical/Ingredient]" ; rdfs:subClassOf . obo:GO_0001932 a rdfs:Class ; rdfs:label "regulation of protein phosphorylation" ; rdfs:comment "Any process that modulates the frequency, rate or extent of addition of phosphate groups into an amino acid in a protein." ; rdfs:subClassOf obo:GO_0031399 , obo:GO_0042325 . obo:OPMI_0000450 a rdfs:Class ; rdfs:label "disease biomarker"@en ; rdfs:comment "A biomarker that is indicative of a disease" ; rdfs:subClassOf obo:OPMI_0000445 . obo:CHEBI_52172 a rdfs:Class ; rdfs:label "nilotinib" ; rdfs:subClassOf obo:CHEBI_140325 , obo:CHEBI_24780 , obo:CHEBI_26421 , obo:CHEBI_39447 , obo:CHEBI_50995 , obo:CHEBI_83565 . obo:NCBITaxon_1868638 a rdfs:Class ; rdfs:label "Bat coronavirus/4620/2014/Glossophaga soricina/Brazil" ; rdfs:subClassOf obo:NCBITaxon_366617 . obo:VO_0005170 a rdfs:Class ; rdfs:label "GX-19" ; rdfs:comment "A SARS-CoV-2 DNA vaccine expressing the SARS-CoV-2 S protein" ; rdfs:subClassOf obo:VO_0005203 . a rdfs:Class ; rdfs:label "Neoplasms, Plasma Cell [Disease/Finding]" ; rdfs:subClassOf . obo:NCBITaxon_264370 a rdfs:Class ; rdfs:label "SARS coronavirus TW" ; rdfs:subClassOf obo:NCBITaxon_694009 . obo:CHEBI_26833 a rdfs:Class ; rdfs:label "sulfur atom" ; rdfs:subClassOf obo:CHEBI_25585 , obo:CHEBI_33303 . obo:NCBITaxon_2724194 a rdfs:Class ; rdfs:label "Avian coronavirus MW05" ; rdfs:subClassOf obo:NCBITaxon_2724161 . obo:CHEBI_76744 a rdfs:Class ; rdfs:label "EC 1.17.* (oxidoreductase acting on CH or CH2) inhibitor" ; rdfs:comment "An oxidoreductase inhibitor which interferes with the action of an oxidoreductase acting on CH or CH2 (EC 1.17.*.*)." ; rdfs:subClassOf obo:CHEBI_76725 . obo:PR_000030918 a rdfs:Class ; rdfs:label "pleckstrin homology domain-containing family A member 5" ; rdfs:comment "A protein that is a translation product of the human PLEKHA5 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:UBERON_0000463 a rdfs:Class ; rdfs:label "organism substance" ; rdfs:comment "Material anatomical entity in a gaseous, liquid, semisolid or solid state; produced by anatomical structures or derived from inhaled and ingested substances that have been modified by anatomical structures as they pass through the body." ; rdfs:subClassOf obo:UBERON_0000465 . a rdfs:Class ; rdfs:label "Na-K ATPases Interactions [MoA]" ; rdfs:subClassOf . obo:NCBITaxon_2691592 a rdfs:Class ; rdfs:label "Scotophilus kuhlii bat coronavirus 512-related" ; rdfs:subClassOf obo:NCBITaxon_2691591 . obo:NCBITaxon_2727852 a rdfs:Class ; rdfs:label "unclassified Nyctacovirus" ; rdfs:subClassOf obo:NCBITaxon_2509503 . obo:NCBITaxon_903628 a rdfs:Class ; rdfs:label "Kenya bat coronavirus BtKY90" ; rdfs:subClassOf obo:NCBITaxon_2664420 . a rdfs:Class ; rdfs:label "Neoplasms, Nerve Tissue [Disease/Finding]" ; rdfs:subClassOf . obo:CIDO_0000443 a rdfs:Class ; rdfs:label "HCoV HKU1 protein"@en ; rdfs:subClassOf obo:CIDO_0000440 , obo:PR_000000001 . obo:CIDO_0020069 a rdfs:Class ; rdfs:label "CareStart COVID-19 MDx RT-PCR" ; rdfs:seeAlso ; rdfs:subClassOf obo:CIDO_0000454 . obo:PR_000015625 a rdfs:Class ; rdfs:label "signal recognition particle 54 kDa protein" ; rdfs:comment "A protein that is a translation product of the human SRP54 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:CIDO_0020092 a rdfs:Class ; rdfs:label "COVID-19 ELISA IgG Antibody Test" ; rdfs:seeAlso ; rdfs:subClassOf obo:CIDO_0000454 . obo:CIDO_0020039 a rdfs:Class ; rdfs:label "Babson Diagnostics aC19G1" ; rdfs:seeAlso ; rdfs:subClassOf obo:CIDO_0000454 . obo:CIDO_0020249 a rdfs:Class ; rdfs:label "QuantiVirus SARS-CoV-2 Multiplex Test Kit" ; rdfs:seeAlso ; rdfs:subClassOf obo:CIDO_0000454 . obo:NCBITaxon_983926 a rdfs:Class ; rdfs:label "Miniopterus bat coronavirus/Kenya/KY27/2006" ; rdfs:subClassOf obo:NCBITaxon_366617 . obo:NCBITaxon_2042572 a rdfs:Class ; rdfs:label "Coronavirus PREDICT CoV-46" ; rdfs:subClassOf obo:NCBITaxon_696098 . obo:PR_P04293 a rdfs:Class ; rdfs:label "DNA polymerase catalytic subunit (Herpes simplex virus type 1 strain 17)" ; rdfs:comment "A protein that is a translation product of the UL30 gene in Herpes simplex virus type 1 strain 17." ; rdfs:subClassOf obo:PR_000036197 . obo:NCBITaxon_11118 a rdfs:Class ; rdfs:label "Coronaviridae" ; rdfs:subClassOf obo:NCBITaxon_2499399 , obo:NCBITaxon_76804 . obo:NCBITaxon_1964811 a rdfs:Class ; rdfs:label "Coronavirus JC81" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:DOID_8645 a rdfs:Class ; rdfs:label "subacute delirium" ; rdfs:subClassOf obo:DOID_8646 . obo:CIDO_0000562 a rdfs:Class ; rdfs:label "VTEDVKFAASTGVID" ; rdfs:comment "A coronavirus epitope that is part of some S protein from HCoV NL63 composed of the following amino acids VTEDVKFAASTGVID" ; rdfs:subClassOf obo:CIDO_0000449 . obo:PR_000012243 a rdfs:Class ; rdfs:label "serine/threonine-protein kinase PAK 4" ; rdfs:comment "A protein that is a translation product of the human PAK4 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:CHEBI_38195 a rdfs:Class ; rdfs:label "5beta-hydroxy steroid" ; rdfs:subClassOf obo:CHEBI_136889 , obo:CHEBI_36848 . obo:OPMI_0000520 a rdfs:Class ; rdfs:label "provenance of measurement record"@en ; rdfs:comment "A provenance of record that determines the provenance of the Measurement record, as in whether the procedure was from an EHR system, insurance claim, registry, or other sources." ; rdfs:subClassOf obo:OPMI_0000512 . obo:CHEBI_22695 a rdfs:Class ; rdfs:label "base" ; rdfs:comment "A molecular entity having an available pair of electrons capable of forming a covalent bond with a hydron (Bronsted base) or with the vacant orbital of some other molecular entity (Lewis base)." ; rdfs:subClassOf obo:CHEBI_51086 . obo:OGG_3000003557 a rdfs:Class ; rdfs:label "IL1RN" ; rdfs:comment "Other designations: IL1 inhibitor|IL1RN (IL1F3)|interleukin-1 receptor antagonist protein|intracellular IL-1 receptor antagonist type II|intracellular interleukin-1 receptor antagonist (icIL-1ra)|type II interleukin-1 receptor antagonist" ; rdfs:subClassOf obo:OGG_2060009606 . obo:CIDO_0000792 a rdfs:Class ; rdfs:label "SARS-CoV2 nsp1 protein binding to human PKP2" ; rdfs:comment "SARS-CoV2 nsp1 protein binding to human PKP2, as evidented by an affinity-purification mass spectrometry experiment" ; rdfs:subClassOf obo:CIDO_0000062 . a rdfs:Class ; rdfs:label "Decreased Protein Synthesis [PE]" ; rdfs:subClassOf , . obo:CIDO_0000014 a rdfs:Class ; rdfs:label "COVID-19 clinical trial drug role"@en ; rdfs:comment "A COVID-19 experimental drug that is under clinical trial testing." ; rdfs:subClassOf obo:CIDO_0000011 . obo:CIDO_0000375 a rdfs:Class ; rdfs:label "SARS-CoV-2 Beta variant"@en ; rdfs:comment "Nextstrain clade 20H" ; rdfs:subClassOf obo:CIDO_0000234 , obo:CIDO_0000407 . obo:NCBITaxon_1788459 a rdfs:Class ; rdfs:label "Hipposideros bat coronavirus BtCoV/3740-2" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:CHEBI_30772 a rdfs:Class ; rdfs:label "butyric acid" ; rdfs:comment "A straight-chain saturated fatty acid that is butane in which one of the terminal methyl groups has been oxidised to a carboxy group." ; rdfs:subClassOf obo:CHEBI_140601 , obo:CHEBI_39418 . obo:PR_000009883 a rdfs:Class ; rdfs:label "protein-lysine 6-oxidase" ; rdfs:comment "A protein that is a translation product of the human LOX gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:CIDO_0000722 a rdfs:Class ; rdfs:label "D1554G in SARS-CoV-2 pp1a protein"@en ; rdfs:comment "An AA variant that has mutated an amino acid at position 1554 into a glycine in pp1a." ; rdfs:subClassOf obo:CIDO_0001074 . obo:CIDO_0001097 a rdfs:Class ; rdfs:label "SARS-CoV2 orf8 protein binding to human PUSL1"@en ; rdfs:comment "SARS-CoV2 orf8 protein binding to human PUSL1, as evidented by an affinity-purification mass spectrometry experiment" ; rdfs:subClassOf obo:CIDO_0000051 . obo:PR_P09488 a rdfs:Class ; rdfs:label "glutathione S-transferase mu 1 (human)" ; rdfs:comment "A glutathione S-transferase mu 1 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000008300 , obo:PR_000029067 . obo:HP_0031862 a rdfs:Class ; rdfs:label "Increased heart rate variability" ; rdfs:comment "Increased variation of beat-to-beat intervals of the heart that occurs in conjunction with the respiratory cycle." ; rdfs:subClassOf obo:HP_0031860 . obo:GO_0051897 a rdfs:Class ; rdfs:label "positive regulation of protein kinase B signaling" ; rdfs:comment "Any process that activates or increases the frequency, rate or extent of protein kinase B signaling, a series of reactions mediated by the intracellular serine/threonine kinase protein kinase B." ; rdfs:subClassOf obo:GO_1902531 , obo:GO_1902533 . obo:CHEBI_58951 a rdfs:Class ; rdfs:label "short-chain fatty acid anion" ; rdfs:comment "Any fatty acid anion obtained by removal of a proton from the carboxy group of a short-chain fatty acid (chain length of less than C6)." ; rdfs:subClassOf obo:CHEBI_28868 . obo:CHEBI_28545 a rdfs:Class ; rdfs:label "valinomycin" ; rdfs:comment "A twelve-membered cyclodepsipeptide composed of three repeating D-alpha-hydroxyisovaleryl-D-valyl-L-lactoyl-L-valyl units joined in sequence. An antibiotic found in several Streptomyces strains." ; rdfs:subClassOf obo:CHEBI_35213 , obo:CHEBI_51026 . a rdfs:Class ; rdfs:label "Metabolism, Inborn Errors [Disease/Finding]" ; rdfs:subClassOf , . obo:NCBITaxon_2691588 a rdfs:Class ; rdfs:label "Miniopterus schreibersii bat coronavirus 1-related" ; rdfs:subClassOf obo:NCBITaxon_2691586 . obo:CIDO_0000454 a rdfs:Class ; rdfs:label "FDA EUA authorized COVID-19 diagnostic testing device"@en ; rdfs:comment "a COVID-19 diagnostic testing device that is authorized to use under the FDA Emergency Use Authorization. The EUA authorized device is not approved to use under other situations other than specified in the letter of EUA authorization by FDA in US."@en ; rdfs:subClassOf obo:CIDO_0000453 . a rdfs:Class ; rdfs:label "Heart Block [Disease/Finding]" ; rdfs:subClassOf . obo:HP_0000223 a rdfs:Class ; rdfs:label "Abnormality of taste sensation" ; rdfs:subClassOf obo:HP_0000271 , obo:HP_0012638 . obo:PR_000014019 a rdfs:Class ; rdfs:label "serine/threonine-protein kinase RIO1" ; rdfs:comment "A protein that is a translation product of the human RIOK1 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:GO_0043523 a rdfs:Class ; rdfs:label "regulation of neuron apoptotic process" ; rdfs:comment "Any process that modulates the occurrence or rate of cell death by apoptotic process in neurons." ; rdfs:subClassOf obo:GO_0042981 , obo:GO_1901214 . obo:CHEBI_17968 a rdfs:Class ; rdfs:label "butyrate" ; rdfs:comment "A short-chain fatty acid anion that is the conjugate base of butyric acid, obtained by deprotonation of the carboxy group." ; rdfs:subClassOf obo:CHEBI_78115 . obo:PR_000013215 a rdfs:Class ; rdfs:label "DNA primase small subunit" ; rdfs:comment "A protein that is a translation product of the human PRIM1 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:PR_Q8WU08 a rdfs:Class ; rdfs:label "serine/threonine-protein kinase 32A (human)" ; rdfs:comment "A serine/threonine-protein kinase 32A that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000015748 , obo:PR_000029067 . obo:OPMI_0000491 a rdfs:Class ; rdfs:label "visit end datetime"@en ; rdfs:comment "The date and time on which a visit ends. For inpatient visits the end date is typically the discharge date. If a Person is still an inpatient in the hospital at the time of the data extract and does not have a visit_end_date, then set the visit_end_date to the date of the data pull." ; rdfs:subClassOf obo:OPMI_0000285 . obo:HP_0002013 a rdfs:Class ; rdfs:label "Vomiting" ; rdfs:comment "Forceful ejection of the contents of the stomach through the mouth by means of a series of involuntary spasmic contractions." ; rdfs:subClassOf obo:HP_0002017 . obo:PR_000016960 a rdfs:Class ; rdfs:label "ubiquitin-associated protein 2-like" ; rdfs:comment "A protein that is a translation product of the human UBAP2L gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:CIDO_0000962 a rdfs:Class ; rdfs:label "SARS-CoV2 nsp9 protein binding to human ZNF503" ; rdfs:comment "SARS-CoV2 nsp9 protein binding to human ZNF503, as evidented by an affinity-purification mass spectrometry experiment" ; rdfs:subClassOf obo:CIDO_0000583 . obo:CIDO_0000069 a rdfs:Class ; rdfs:label "chemical role modulating host immune response"@en ; rdfs:comment "A role of a chemical effective in modulating host response" ; rdfs:subClassOf obo:CHEBI_51086 . obo:CHEBI_8228 a rdfs:Class ; rdfs:label "pioglitazone" ; rdfs:comment "A member of the class of thiazolidenediones that is 1,3-thiazolidine-2,4-dione substituted by a benzyl group at position 5 which in turn is substituted by a 2-(5-ethylpyridin-2-yl)ethoxy group at position 4 of the phenyl ring. It exhibits hypoglycemic activity." ; rdfs:subClassOf obo:CHEBI_26421 , obo:CHEBI_35618 , obo:CHEBI_50990 . obo:CHEBI_32458 a rdfs:Class ; rdfs:label "cysteinium" ; rdfs:subClassOf obo:CHEBI_33719 . obo:NCBITaxon_535602 a rdfs:Class ; rdfs:label "Bovine coronavirus UP2/PRT/2005" ; rdfs:subClassOf obo:NCBITaxon_11128 . obo:CIDO_0001155 a rdfs:Class ; rdfs:label "AA variant in SARS-CoV-2 protein SD1 S1 region"@en ; rdfs:subClassOf obo:CIDO_0000592 . obo:GO_0043524 a rdfs:Class ; rdfs:label "negative regulation of neuron apoptotic process" ; rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of cell death by apoptotic process in neurons." ; rdfs:subClassOf obo:GO_0043066 , obo:GO_0043523 , obo:GO_1901215 . obo:NCBITaxon_228607 a rdfs:Class ; rdfs:label "SARS coronavirus BJ04" ; rdfs:subClassOf obo:NCBITaxon_694009 . obo:CHEBI_26775 a rdfs:Class ; rdfs:label "stilbene" ; rdfs:subClassOf obo:CHEBI_22712 , obo:CHEBI_78840 . obo:CHEBI_92304 a rdfs:Class ; rdfs:label "2-(3,4-dichlorophenyl)-N-methyl-N-[2-(1-pyrrolidinyl)ethyl]ethanamine" ; rdfs:subClassOf obo:CHEBI_32877 . obo:CHEBI_53000 a rdfs:Class ; rdfs:label "epitope" ; rdfs:comment "The biological role played by a material entity when bound by a receptor of the adaptive immune system. Specific site on an antigen to which an antibody binds." ; rdfs:subClassOf obo:CHEBI_24432 . obo:CIDO_0000673 a rdfs:Class ; rdfs:label "H655Y in SARS-CoV-2 S protein" ; rdfs:comment "An AA mutation or AA variant that has mutated an amino acid at position 655 into a tyrosine in S protein." ; rdfs:subClassOf obo:CIDO_0000592 . obo:CIDO_0000313 a rdfs:Class ; rdfs:label "homologous epitope"@en ; rdfs:subClassOf obo:OBI_1110001 . obo:HP_0000083 a rdfs:Class ; rdfs:label "Renal insufficiency" ; rdfs:comment "A reduction in the level of performance of the kidneys in areas of function comprising the concentration of urine, removal of wastes, the maintenance of electrolyte balance, homeostasis of blood pressure, and calcium metabolism." ; rdfs:subClassOf obo:HP_0000118 . obo:PR_000050285 a rdfs:Class ; rdfs:label "helicase (SARS-CoV-2)" ; rdfs:comment "An ORF1ab proteolytic cleavage product (SARS-CoV-2) that is the central portion produced by the enzymatic action of 3CL-PRO proteinase (nsp5) when it cleaves the precursor replicase polyprotein 1ab (SARS-CoV-2) between residues 5324-5325 and 5925-5926. UniProtKB:P0DTD1, 4393-5324." ; rdfs:subClassOf obo:PR_000050283 . obo:PR_000010131 a rdfs:Class ; rdfs:label "mitogen-activated protein kinase kinase kinase 12" ; rdfs:comment "A protein that is a translation product of the human MAP3K12 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:NCBITaxon_741999 a rdfs:Class ; rdfs:label "Bat SARS coronavirus HKU3-12" ; rdfs:subClassOf obo:NCBITaxon_442736 . obo:NCBITaxon_338606 a rdfs:Class ; rdfs:label "Bat SARS coronavirus HKU3-3" ; rdfs:subClassOf obo:NCBITaxon_442736 . obo:CIDO_0000611 a rdfs:Class ; rdfs:label "N440K in SARS-CoV-2 S protein"@en ; rdfs:comment "An AA mutation or AA variant that has mutated an amino acid at position 211 into a lysine in S protein." ; rdfs:subClassOf obo:CIDO_0001157 . obo:NCBITaxon_424369 a rdfs:Class ; rdfs:label "Bat coronavirus HKU9-3" ; rdfs:subClassOf obo:NCBITaxon_694006 . obo:NCBITaxon_117570 a rdfs:Class ; rdfs:label "Teleostomi" ; rdfs:subClassOf obo:NCBITaxon_7776 . obo:NCBITaxon_2509505 a rdfs:Class ; rdfs:label "Pedacovirus" ; rdfs:subClassOf obo:NCBITaxon_693996 . obo:NCBITaxon_2042565 a rdfs:Class ; rdfs:label "Coronavirus PREDICT CoV-4" ; rdfs:subClassOf obo:NCBITaxon_366617 . obo:NCBITaxon_742003 a rdfs:Class ; rdfs:label "Bat SARS coronavirus HKU3-6" ; rdfs:subClassOf obo:NCBITaxon_442736 . obo:NCBITaxon_263509 a rdfs:Class ; rdfs:label "Acinonyx jubatus coronavirus" ; rdfs:subClassOf obo:NCBITaxon_12663 . obo:GO_0050974 a rdfs:Class ; rdfs:label "detection of mechanical stimulus involved in sensory perception" ; rdfs:comment "The series of events in which a mechanical stimulus is received and converted into a molecular signal as part of sensory perception." ; rdfs:subClassOf obo:GO_0050906 , obo:GO_0050982 . obo:GO_0031323 a rdfs:Class ; rdfs:label "regulation of cellular metabolic process" ; rdfs:comment "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways by which individual cells transform chemical substances." ; rdfs:subClassOf obo:GO_0019222 , obo:GO_0050794 . obo:DRON_00061963 a rdfs:Class ; rdfs:label "Promethazine Hydrochloride 25 MG/ML Injectable Solution" ; rdfs:subClassOf obo:DRON_00023182 . obo:OGG_1000009606 a rdfs:Class ; rdfs:label "genome of Homo sapiens" ; rdfs:comment "The genome of an organism of Homo sapiens" ; rdfs:subClassOf obo:OGG_1000002759 . obo:PR_000001481 a rdfs:Class ; rdfs:label "low affinity immunoglobulin gamma Fc region receptor II-b" ; rdfs:comment "An immunoglobulin gamma Fc receptor II/III/IV that is a translation product of the human FCGR2B gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000001355 . obo:HP_0002878 a rdfs:Class ; rdfs:label "Respiratory failure" ; rdfs:comment "A severe form of respiratory insufficiency characterized by inadequate gas exchange such that the levels of oxygen or carbon dioxide cannot be maintained within normal limits." ; rdfs:subClassOf obo:HP_0002795 . obo:NCBITaxon_389247 a rdfs:Class ; rdfs:label "Bat coronavirus (BtCoV/A1203/2005)" ; rdfs:subClassOf obo:NCBITaxon_389126 . obo:CHEBI_36059 a rdfs:Class ; rdfs:label "hydroxy monocarboxylic acid anion" ; rdfs:comment "Any monocarboxylic acid anion carrying at least one hydroxy substituent." ; rdfs:subClassOf obo:CHEBI_35757 . obo:NCBITaxon_749428 a rdfs:Class ; rdfs:label "Pintail coronavirus PBA-10" ; rdfs:subClassOf obo:NCBITaxon_749416 . obo:CHEBI_63367 a rdfs:Class ; rdfs:label "monosaccharide derivative" ; rdfs:comment "A carbohydrate derivative that is formally obtained from a monosaccharide." ; rdfs:subClassOf obo:CHEBI_63299 . obo:CHEBI_38976 a rdfs:Class ; rdfs:label "alkylbenzene" ; rdfs:comment "A monocyclic arene that is benzene substituted with one or more alkyl groups." ; rdfs:subClassOf obo:CHEBI_22712 , obo:CHEBI_33847 . obo:PR_000006781 a rdfs:Class ; rdfs:label "dual specificity tyrosine-phosphorylation-regulated kinase 1A" ; rdfs:comment "A protein that is a translation product of the human DYRK1A gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:CHEBI_76969 a rdfs:Class ; rdfs:label "bacterial metabolite" ; rdfs:comment "Any prokaryotic metabolite produced during a metabolic reaction in bacteria." ; rdfs:subClassOf obo:CHEBI_75787 . obo:PR_000017193 a rdfs:Class ; rdfs:label "inactive ubiquitin carboxyl-terminal hydrolase 54" ; rdfs:comment "A protein that is a translation product of the human USP54 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:OBI_0002972 a rdfs:Class ; rdfs:label "endotracheal aspirate specimen" ; rdfs:comment "A specimen that derives from a biofilm that forms on the inner surface of an endotracheal tube while the tube is in the trachea. The specimen is collected by suction without removing the tube." ; rdfs:subClassOf obo:OBI_0001479 . obo:DRON_00010111 a rdfs:Class ; rdfs:label "Hydroxychloroquine" ; rdfs:subClassOf obo:OBI_0000047 . obo:CHEBI_83399 a rdfs:Class ; rdfs:label "marine xenobiotic metabolite" ; rdfs:comment "Any metabolite produced by metabolism of a xenobiotic compound in marine macro- and microorganisms." ; rdfs:subClassOf obo:CHEBI_76206 , obo:CHEBI_76507 . a rdfs:Class ; rdfs:label "Kinase Inhibitors [MoA]" ; rdfs:subClassOf . obo:NCBITaxon_756649 a rdfs:Class ; rdfs:label "Bovine coronavirus cow/WDBR-9215/BRA/2003" ; rdfs:subClassOf obo:NCBITaxon_11128 . obo:CHEBI_170007 a rdfs:Class ; rdfs:label "Nirmatrelvir" ; rdfs:comment "An azabicyclohexane that is (1R,5S)-3-azabicyclo[3.1.0]hexane substituted by {(1S)-1-cyano-2-[(3S)-2-oxopyrrolidin-3-yl]ethyl}aminoacyl, 3-methyl-N-(trifluoroacetyl)-L-valinamide, methyl and methyl groups at positions 2S, 3, 6 and 6, respectively. It is an inhibitor of SARS-CoV-2 main protease which is currently under clinical development for the treatment of COVID-19." ; rdfs:subClassOf obo:CHEBI_140325 , obo:CHEBI_140326 , obo:CHEBI_170008 , obo:CHEBI_18379 , obo:CHEBI_37143 , obo:CHEBI_46770 , obo:CHEBI_74223 . obo:CHEBI_32836 a rdfs:Class ; rdfs:label "L-serinate" ; rdfs:comment "A serinate that is the conjugate base of L-serine, obtained by deprotonation of the carboxy group." ; rdfs:subClassOf obo:CHEBI_32845 , obo:CHEBI_59814 . a rdfs:Class ; rdfs:label "Decreased Disorganized Electrical Activity [PE]" ; rdfs:subClassOf . obo:NCBITaxon_389153 a rdfs:Class ; rdfs:label "Bat coronavirus (BtCoV/A898/2005)" ; rdfs:subClassOf obo:NCBITaxon_389126 . obo:NCBITaxon_1297661 a rdfs:Class ; rdfs:label "Munia coronavirus HKU13" ; rdfs:subClassOf obo:NCBITaxon_2509474 . obo:CHEBI_29986 a rdfs:Class ; rdfs:label "D-glutamate(1-)" ; rdfs:comment "An alpha-amino-acid anion that is the conjugate base of D-glutamic acid, having anionic carboxy groups and a cationic amino group" ; rdfs:subClassOf obo:CHEBI_14321 . obo:NCBITaxon_389137 a rdfs:Class ; rdfs:label "Bat coronavirus (BtCoV/A613/2005)" ; rdfs:subClassOf obo:NCBITaxon_389126 . obo:NCBITaxon_1159903 a rdfs:Class ; rdfs:label "Magpie-robin coronavirus HKU18" ; rdfs:subClassOf obo:NCBITaxon_2724161 . obo:HP_0002204 a rdfs:Class ; rdfs:label "Pulmonary embolism" ; rdfs:comment "An embolus (that is, an abnormal particle circulating in the blood) located in the pulmonary artery and thereby blocking blood circulation to the lung. Usually the embolus is a blood clot that has developed in an extremity (for instance, a deep venous thrombosis), detached, and traveled through the circulation before becoming trapped in the pulmonary artery." ; rdfs:subClassOf obo:HP_0030875 . obo:PR_000013793 a rdfs:Class ; rdfs:label "RNA-binding protein 28" ; rdfs:comment "A protein that is a translation product of the human RBM28 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:PR_000016495 a rdfs:Class ; rdfs:label "non-receptor tyrosine-protein kinase TNK1" ; rdfs:comment "A protein that is a translation product of the human TNK1 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:CHEBI_76956 a rdfs:Class ; rdfs:label "Aspergillus metabolite" ; rdfs:comment "Any fungal metabolite produced during a metabolic reaction in the mould, Aspergillus." ; rdfs:subClassOf obo:CHEBI_76946 . obo:NCBITaxon_903598 a rdfs:Class ; rdfs:label "Kenya bat coronavirus BtKY60" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:CHEBI_65255 a rdfs:Class ; rdfs:label "food preservative" ; rdfs:comment "Substances which are added to food in order to prevent decomposition caused by microbial growth or by undesirable chemical changes." ; rdfs:subClassOf obo:CHEBI_64047 . obo:DRON_00882939 a rdfs:Class ; rdfs:label "remdesivir" ; rdfs:subClassOf obo:OBI_0000047 . obo:RO_0002606 a rdf:Property ; rdfs:label "is substance that treats" ; rdfs:comment "c is a substance that treats d if c is a material entity (such as a small molecule or compound) and d is a pathological process, phenotype or disease, and c is capable of some activity that negative regulates or decreases the magnitude of d." ; rdfs:seeAlso ; rdfs:range ; rdfs:subPropertyOf obo:RO_0002599 . obo:CIDO_0001025 a rdfs:Class ; rdfs:label "Mosedipimod" ; rdfs:subClassOf obo:CHEBI_23367 . obo:IDO_0000477 a rdfs:Class ; rdfs:label "acute infectious disease course"@en ; rdfs:comment "An infectious disease course that begins soon after infection is established and progresses rapidly to severe stages."@en ; rdfs:subClassOf obo:IDO_0000495 . obo:NCBITaxon_231471 a rdfs:Class ; rdfs:label "Avian infectious bronchitis virus (strain Arkansas 99)" ; rdfs:subClassOf obo:NCBITaxon_11120 . obo:CIDO_0000241 a rdfs:Class ; rdfs:label "L84S in SARS-CoV-2 NS8 protein"@en ; rdfs:comment "ORF8-L84S is SNP variant that occurs at T28144C at ORF8 protein, which is shown in a SARS-CoV-2 clade S variant virus." ; rdfs:subClassOf obo:CIDO_0000617 . obo:OBI_0000806 a rdfs:Class ; rdfs:label "material maintenance objective" ; rdfs:comment "An objective specification maintains some or all of the qualities of a material over time." ; rdfs:subClassOf obo:IAO_0000005 . obo:PR_000012742 a rdfs:Class ; rdfs:label "phosphatidylinositol 5-phosphate 4-kinase type-2 beta" ; rdfs:comment "A protein that is a translation product of the human PIP4K2B gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:CIDO_0020203 a rdfs:Class ; rdfs:label "MGH COVID-19 qPCR assay" ; rdfs:seeAlso ; rdfs:subClassOf obo:CIDO_0000454 . a rdfs:Class ; rdfs:label "Amines [Chemical/Ingredient]" ; rdfs:subClassOf . obo:VO_0005246 a rdfs:Class ; rdfs:label "COVIVAC"@en ; rdfs:comment "A SARS-CoV-2 recombinant Newcastle Disease Virus vector vaccine expressing membrane-anchored pre-fusion-stabilized trimeric SARS-CoV-2 S protein" ; rdfs:subClassOf obo:VO_0005199 . a rdfs:Class ; rdfs:label "Dysentery, Bacillary [Disease/Finding]" ; rdfs:subClassOf , . obo:PR_Q9BQI3 a rdfs:Class ; rdfs:label "eukaryotic translation initiation factor 2-alpha kinase 1 (human)" ; rdfs:comment "A eukaryotic translation initiation factor 2-alpha kinase 1 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000006958 , obo:PR_000029067 . obo:PR_P62877 a rdfs:Class ; rdfs:label "E3 ubiquitin-protein ligase RBX1 (human)" ; rdfs:comment "An E3 ubiquitin-protein ligase RBX1 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000000043 , obo:PR_000029067 . a rdfs:Class ; rdfs:label "Indole Alkaloids [Chemical/Ingredient]" ; rdfs:subClassOf , . obo:PR_000001175 a rdfs:Class ; rdfs:label "D(1A) dopamine receptor" ; rdfs:comment "A D(1)-like dopamine receptor that is a translation product of the human DRD1 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000001107 . obo:CHEBI_28863 a rdfs:Class ; rdfs:label "flavanones" ; rdfs:comment "Members of the class of flavans with a 3,4-dihydro-2-aryl-2H-1-benzopyran-4-one skeleton and its substituted derivatives." ; rdfs:subClassOf obo:CHEBI_38672 , obo:CHEBI_3992 . obo:CIDO_0000289 a rdfs:Class ; rdfs:label "MERS-CoV shedding"@en ; rdfs:subClassOf obo:CIDO_0000202 . obo:CHEBI_24613 a rdfs:Class ; rdfs:label "homodetic cyclic peptide" ; rdfs:comment "A homodetic cyclic peptide is a cyclic peptide in which the ring consists solely of amino-acid residues in peptide linkages." ; rdfs:subClassOf obo:CHEBI_23449 . obo:CHEBI_22501 a rdfs:Class ; rdfs:label "aminodiol" ; rdfs:comment "An amino alcohol having two hydroxy functional groups." ; rdfs:subClassOf obo:CHEBI_22478 , obo:CHEBI_23824 . obo:CIDO_0000215 a rdfs:Class ; rdfs:label "SARS-CoV-2 E protein synthesis"@en ; rdfs:subClassOf obo:CIDO_0000213 . obo:CIDO_0001142 a rdfs:Class ; rdfs:label "SARS-CoV-2 BA.1 virus"@en ; rdfs:comment "A SARS-CoV-2 Omicron variant virus that has a majority of the following mutations:" ; rdfs:subClassOf obo:CIDO_0000406 , obo:CIDO_0000590 . obo:HP_0010932 a rdfs:Class ; rdfs:label "Abnormal circulating nucleobase concentration" ; rdfs:comment "An abnormality of a nucleobase metabolic process." ; rdfs:subClassOf obo:HP_0001939 , obo:HP_0004364 . obo:CHEBI_38207 a rdfs:Class ; rdfs:label "aminopyridine" ; rdfs:comment "Compounds containing a pyridine skeleton substituted by one or more amine groups." ; rdfs:subClassOf obo:CHEBI_26421 , obo:CHEBI_33860 . obo:NCBITaxon_233265 a rdfs:Class ; rdfs:label "Avian infectious bronchitis virus (strain DE072)" ; rdfs:subClassOf obo:NCBITaxon_11120 . obo:GO_0050792 a rdfs:Class ; rdfs:label "regulation of viral process" ; rdfs:comment "Any process that modulates the rate or extent of the viral life cycle, the set of processes by which a virus reproduces and spreads among hosts." ; rdfs:subClassOf obo:GO_0050789 . obo:PR_000004990 a rdfs:Class ; rdfs:label "calcium/calmodulin-dependent protein kinase type 1G" ; rdfs:comment "A protein that is a translation product of the human CAMK1G gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:HP_0001370 a rdfs:Class ; rdfs:label "Rheumatoid arthritis" ; rdfs:comment "Inflammatory changes in the synovial membranes and articular structures with widespread fibrinoid degeneration of the collagen fibers in mesenchymal tissues, as well as atrophy and rarefaction of bony structures." ; rdfs:subClassOf obo:HP_0001369 . obo:NCBITaxon_9665 a rdfs:Class ; rdfs:label "Mustela" ; rdfs:subClassOf obo:NCBITaxon_169418 . a rdfs:Class ; rdfs:label "Hiccup [Disease/Finding]" ; rdfs:subClassOf . a rdfs:Class ; rdfs:label "Saliva Production Alteration [PE]" ; rdfs:subClassOf . a rdfs:Class ; rdfs:label "Urinary Bladder Diseases [Disease/Finding]" ; rdfs:subClassOf . a rdfs:Class ; rdfs:label "Uterine Function Alteration [PE]" ; rdfs:subClassOf . obo:PR_Q15139 a rdfs:Class ; rdfs:label "serine/threonine-protein kinase D1 (human)" ; rdfs:comment "A serine/threonine-protein kinase D1 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000013236 , obo:PR_000029067 . obo:CHEBI_23765 a rdfs:Class ; rdfs:label "quinolone" ; rdfs:subClassOf obo:CHEBI_26513 . obo:GO_0043410 a rdfs:Class ; rdfs:label "positive regulation of MAPK cascade" ; rdfs:comment "Any process that activates or increases the frequency, rate or extent of signal transduction mediated by the MAPK cascade." ; rdfs:subClassOf obo:GO_0043408 , obo:GO_1902533 . obo:CIDO_0000745 a rdfs:Class ; rdfs:label "S3159T in SARS-CoV-2 pp1a protein"@en ; rdfs:comment "An AA mutation or AA variant that has mutated an amino acid at position 3159 into threonine in pp1a." ; rdfs:subClassOf obo:CIDO_0001075 . obo:PR_000003031 a rdfs:Class ; rdfs:label "focal adhesion kinase 1" ; rdfs:comment "A focal adhesion kinase that is a translation product of the human PTK2 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000003030 . obo:GO_0001934 a rdfs:Class ; rdfs:label "positive regulation of protein phosphorylation" ; rdfs:comment "Any process that activates or increases the frequency, rate or extent of addition of phosphate groups to amino acids within a protein." ; rdfs:subClassOf obo:GO_0001932 , obo:GO_0031401 , obo:GO_0042327 . obo:HP_0012735 a rdfs:Class ; rdfs:label "Cough" ; rdfs:comment "A sudden, audible expulsion of air from the lungs through a partially closed glottis, preceded by inhalation." ; rdfs:subClassOf obo:HP_0002795 . obo:PR_P51451 a rdfs:Class ; rdfs:label "tyrosine-protein kinase Blk (human)" ; rdfs:comment "A tyrosine-protein kinase BLK that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000004758 , obo:PR_000029067 . obo:PR_O60674 a rdfs:Class ; rdfs:label "tyrosine-protein kinase JAK2 (human)" ; rdfs:comment "A tyrosine-protein kinase JAK2 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000009197 , obo:PR_000029067 . obo:NCBITaxon_1788475 a rdfs:Class ; rdfs:label "Miniopterus bat coronavirus BtCoV/4036-1" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:PR_000011054 a rdfs:Class ; rdfs:label "NEDD4 family-interacting protein 2" ; rdfs:comment "A protein that is a translation product of the human NDFIP2 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:CIDO_0000692 a rdfs:Class ; rdfs:label "S371L in SARS-CoV-2 S protein" ; rdfs:comment "An AA mutation or AA variant that has mutated an amino acid at position 371 into a leucine in S protein." ; rdfs:subClassOf obo:CIDO_0000593 . obo:CHEBI_36829 a rdfs:Class ; rdfs:label "polyatomic monoanion" ; rdfs:subClassOf obo:CHEBI_33273 , obo:CHEBI_36830 . obo:CIDO_0000492 a rdfs:Class ; rdfs:label "ALDKLYKVFGSPVMT" ; rdfs:comment "A coronavirus epitope that is part of some S protein from HCoV 229E composed of the following amino acids ALDKLYKVFGSPVMT" ; rdfs:subClassOf obo:CIDO_0000451 . obo:PR_Q8WUY8 a rdfs:Class ; rdfs:label "probable N-acetyltransferase 14 (human)" ; rdfs:comment "A probable N-acetyltransferase 14 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000010999 , obo:PR_000029067 . obo:PR_000014560 a rdfs:Class ; rdfs:label "stromal cell-derived factor 2" ; rdfs:comment "A protein that is a translation product of the human SDF2 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:UBERON_0015212 a rdfs:Class ; rdfs:label "lateral structure" ; rdfs:comment "Any structure that is placed on one side of the left-right axis of a bilaterian." ; rdfs:subClassOf obo:UBERON_0000061 . obo:CIDO_0020302 a rdfs:Class ; rdfs:label "T2SARS-CoV-2 Panel" ; rdfs:seeAlso ; rdfs:subClassOf obo:CIDO_0000454 . obo:NCBITaxon_1788425 a rdfs:Class ; rdfs:label "Bat coronavirus MsBtCoV/3710" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:NCBITaxon_566559 a rdfs:Class ; rdfs:label "Bat coronavirus Trinidad/1CO7BA/2007" ; rdfs:subClassOf obo:NCBITaxon_366617 . obo:PR_000002196 a rdfs:Class ; rdfs:label "caspase-3-like protease" ; rdfs:comment "A protein that is a translation product of a gene family that includes CASP3, CASP6, and CASP7 genes. The core architecture consists of a Caspase domain (Pfam:PF00656). Encoded as zymogens, the activated proteins are cysteine proteases typically involved in apoptosis." ; rdfs:subClassOf obo:PR_000000001 . obo:NCBITaxon_749417 a rdfs:Class ; rdfs:label "Black-headed gull coronavirus CIR-66144" ; rdfs:subClassOf obo:NCBITaxon_749416 . obo:NCBITaxon_385687 a rdfs:Class ; rdfs:label "SARS coronavirus WF188" ; rdfs:subClassOf obo:NCBITaxon_694009 . obo:CHEBI_23990 a rdfs:Class ; rdfs:label "ethyl ester" ; rdfs:comment "Any carboxylic ester resulting from the formal condensation of the carboxy group of a carboxylic acid with ethanol." ; rdfs:subClassOf obo:CHEBI_33308 . obo:HP_0032262 a rdfs:Class ; rdfs:label "Pulmonary tuberculosis" ; rdfs:comment "A lung infection by Mycobacterium tuberculosis a slightly curved non-motile, aerobic, non-capsulated and non-spore forming strains of mycobacteria." ; rdfs:subClassOf obo:HP_0032101 . a rdfs:Class ; rdfs:label "Obsessive-Compulsive Disorder [Disease/Finding]" ; rdfs:subClassOf . obo:GO_0006950 a rdfs:Class ; rdfs:label "response to stress" ; rdfs:comment "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a disturbance in organismal or cellular homeostasis, usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation)." ; rdfs:subClassOf obo:GO_0050896 . obo:GO_0006364 a rdfs:Class ; rdfs:label "rRNA processing" ; rdfs:comment "Any process involved in the conversion of a primary ribosomal RNA (rRNA) transcript into one or more mature rRNA molecules." ; rdfs:subClassOf obo:GO_0034470 , obo:GO_0034660 . obo:CHEBI_3063 a rdfs:Class ; rdfs:label "Berbamine" ; rdfs:subClassOf obo:CHEBI_133004 , obo:CHEBI_24922 . a rdfs:Class ; rdfs:label "Macrocyclic Compounds [Chemical/Ingredient]" ; rdfs:subClassOf . obo:NCBITaxon_1163669 a rdfs:Class ; rdfs:label "Murine hepatitis virus strain S/3239-17" ; rdfs:subClassOf obo:NCBITaxon_11138 . obo:PR_Q969X5 a rdfs:Class ; rdfs:label "endoplasmic reticulum-Golgi intermediate compartment protein 1 (human)" ; rdfs:comment "An endoplasmic reticulum-Golgi intermediate compartment protein 1 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000007174 , obo:PR_000029067 . obo:CIDO_0000440 a rdfs:Class ; rdfs:label "coronavirus protein" ; rdfs:comment "A virus protein where the virus is a member of Coronivirinae."@en ; rdfs:subClassOf obo:PR_000000001 , obo:VO_0010754 . obo:PR_000007887 a rdfs:Class ; rdfs:label "GRIP and coiled-coil domain-containing protein 2" ; rdfs:comment "A protein that is a translation product of the human GCC2 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:PR_000014189 a rdfs:Class ; rdfs:label "60S ribosomal protein L10-like" ; rdfs:comment "A protein that is a translation product of the human RPL10L gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:NCBITaxon_2591233 a rdfs:Class ; rdfs:label "Coronavirus BtRl-BetaCoV/SC2018" ; rdfs:subClassOf obo:NCBITaxon_2720068 . obo:CHEBI_24834 a rdfs:Class ; rdfs:label "inorganic anion" ; rdfs:subClassOf obo:CHEBI_22563 , obo:CHEBI_36914 . obo:CIDO_0000727 a rdfs:Class ; rdfs:label "T3646A in SARS-CoV-2 pp1a protein"@en ; rdfs:comment "An AA mutation or AA variant that has mutated an amino acid at position 3646 into alanine in pp1a." ; rdfs:subClassOf obo:CIDO_0001077 . obo:PR_000014165 a rdfs:Class ; rdfs:label "proto-oncogene tyrosine-protein kinase ROS" ; rdfs:comment "A protein that is a translation product of the human ROS1 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:NCBITaxon_2042554 a rdfs:Class ; rdfs:label "Coronavirus PREDICT CoV-28" ; rdfs:subClassOf obo:NCBITaxon_366617 . obo:CIDO_0000334 a rdfs:Class ; rdfs:label "CAQKFNGLTVLPPLL"@en ; rdfs:subClassOf obo:CIDO_0000314 . obo:CIDO_0001222 a rdfs:Class ; rdfs:label "SARS-CoV-2 Nucleic Acid Detection Kit RNA (combined probe-anchored polymerization sequencing method) (BGI BIOTECHNOLOGY (WUHAN) Co., Ltd.)" ; rdfs:comment "Poduct storage conditions and expiration date: Packing box 1 and packing box 2 should be kept below -18℃, and packing box 3 should be stored at 2℃～8℃, and the validity period is 6 months." ; rdfs:subClassOf obo:CIDO_0000021 . obo:OAE_0004326 a rdfs:Class ; rdfs:label "lymphoplasmacytic myocarditis AE"@en ; rdfs:comment "a myocarditis AE where the heart muscle is filled with lymphocytes and plasma cells that are not normally seen." ; rdfs:subClassOf obo:OAE_0001201 . obo:NCBITaxon_296840 a rdfs:Class ; rdfs:label "SARS coronavirus PC4-199" ; rdfs:subClassOf obo:NCBITaxon_694009 . a rdfs:Class ; rdfs:label "Positive Inotropy [PE]" ; rdfs:subClassOf . obo:IAO_0000102 a rdfs:Class ; rdfs:label "data about an ontology part"@en ; rdfs:comment "Data about an ontology part is a data item about a part of an ontology, for example a term"@en ; rdfs:subClassOf obo:IAO_0000027 . obo:CIDO_0000367 a rdfs:Class ; rdfs:label "respirator"@en ; rdfs:comment "A respirator designed to protect the user from breathing in contaminants in the air, thus preserving the health of their respiratory tract." ; rdfs:subClassOf obo:CIDO_0000365 . obo:PR_Q7KZI7 a rdfs:Class ; rdfs:label "serine/threonine-protein kinase MARK2 (human)" ; rdfs:comment "A serine/threonine-protein kinase MARK2 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000010187 , obo:PR_000029067 . obo:HP_0002788 a rdfs:Class ; rdfs:label "Recurrent upper respiratory tract infections" ; rdfs:comment "An increased susceptibility to upper respiratory tract infections as manifested by a history of recurrent upper respiratory tract infections (running ears - otitis, sinusitis, pharyngitis, tonsillitis)." ; rdfs:subClassOf obo:HP_0001739 , obo:HP_0002205 . obo:NCBITaxon_1415831 a rdfs:Class ; rdfs:label "Bat SARS-like coronavirus Rs3262-2" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:SO_0000110 a rdfs:Class ; rdfs:subClassOf obo:IAO_0000030 . a rdfs:Class ; rdfs:label "Cardiac Rate Alteration [PE]" ; rdfs:subClassOf . obo:NCBITaxon_1788464 a rdfs:Class ; rdfs:label "Miniopterus bat coronavirus BtCoV/3736-2" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:HP_0100646 a rdfs:Class ; rdfs:label "Thyroiditis" ; rdfs:comment "Inflammation of the thyroid gland." ; rdfs:subClassOf obo:HP_0000820 , obo:HP_0012649 . obo:NCBITaxon_1699352 a rdfs:Class ; rdfs:label "Rousettus Bat Betacoronavirus strain ML_101I" ; rdfs:subClassOf obo:NCBITaxon_696098 . obo:CIDO_0020267 a rdfs:Class ; rdfs:label "SalivaDirect" ; rdfs:seeAlso ; rdfs:subClassOf obo:CIDO_0000454 . obo:VO_0004999 a rdfs:Class ; rdfs:label "AKS-452"@en ; rdfs:comment "A SARS-CoV-2-RBD-Fc fusion protein designed to induce or boost a Th1/Th2 mixed immune response in patients against the Receptor Binding Domain (RBD) of the novel coronavirus spike protein." ; rdfs:subClassOf obo:VO_0005202 . obo:CHEBI_57491 a rdfs:Class ; rdfs:label "staurosporinium" ; rdfs:comment "Conjugate acid of staurosporine." ; rdfs:subClassOf obo:CHEBI_35274 . a rdfs:Class ; rdfs:label "Decreased Autonomic Nervous System Norepinephrine Activity [PE]" ; rdfs:subClassOf . obo:NCBITaxon_1532166 a rdfs:Class ; rdfs:label "Alphacoronavirus BtCoV/GrNC3/Neo_cap/RSA/2012" ; rdfs:subClassOf obo:NCBITaxon_366617 . obo:PR_A7MCY6 a rdfs:Class ; rdfs:label "TANK-binding kinase 1-binding protein 1 (human)" ; rdfs:comment "A TANK-binding kinase 1-binding protein 1 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000016131 , obo:PR_000029067 . obo:CHEBI_70709 a rdfs:Class ; rdfs:label "progesterone receptor agonist" ; rdfs:comment "A hormone agonist that binds to and activates progesterone receptors." ; rdfs:subClassOf obo:CHEBI_51060 . obo:CIDO_0000873 a rdfs:Class ; rdfs:label "SARS-CoV2 nsp2 protein binding to human RAP1GDS1" ; rdfs:comment "SARS-CoV2 nsp2 protein binding to human RAP1GDS1, as evidented by an affinity-purification mass spectrometry experiment" ; rdfs:subClassOf obo:CIDO_0000580 . obo:CHEBI_37142 a rdfs:Class ; rdfs:label "organoiodine compound" ; rdfs:comment "An organoiodine compound is a compound containing at least one carbon-iodine bond." ; rdfs:subClassOf obo:CHEBI_17792 , obo:CHEBI_24860 . obo:CHEBI_17698 a rdfs:Class ; rdfs:label "chloramphenicol" ; rdfs:comment "An organochlorine compound that is dichloro-substituted acetamide containing a nitrobenzene ring, an amide bond and two alcohol functions." ; rdfs:subClassOf obo:CHEBI_23824 , obo:CHEBI_35716 , obo:CHEBI_36683 , obo:CHEBI_37622 . obo:NCBITaxon_389250 a rdfs:Class ; rdfs:label "Bat coronavirus (BtCoV/A429/2005)" ; rdfs:subClassOf obo:NCBITaxon_389126 . a rdfs:Class ; rdfs:label "Epstein-Barr Virus Infections [Disease/Finding]" ; rdfs:subClassOf , . obo:PR_Q9Y5J9 a rdfs:Class ; rdfs:label "mitochondrial import inner membrane translocase subunit Tim8 B (human)" ; rdfs:comment "A mitochondrial import inner membrane translocase subunit Tim8 B that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000016350 , obo:PR_000029067 . a rdfs:Class ; rdfs:label "D [Preparations]" ; rdfs:subClassOf . obo:CIDO_0000548 a rdfs:Class ; rdfs:label "RLHNFSIISGTAFLG" ; rdfs:comment "A coronavirus epitope that is part of some S protein from HCoV 229E composed of the following amino acids RLHNFSIISGTAFLG" ; rdfs:subClassOf obo:CIDO_0000451 . a rdfs:Class ; rdfs:label "Brain Diseases, Metabolic [Disease/Finding]" ; rdfs:subClassOf , . obo:CHEBI_90710 a rdfs:Class ; rdfs:label "receptor modulator" ; rdfs:comment "A drug that acts as an antagonist, agonist, reverse agonist, or in some other fashion when interacting with cellular receptors." ; rdfs:subClassOf obo:CHEBI_23888 . obo:CIDO_0000652 a rdfs:Class ; rdfs:label "Y505H in SARS-CoV-2 S protein"@en ; rdfs:comment "An AA mutation or AA variant that has mutated an amino acid at position 505 into a histidine in S protein." ; rdfs:subClassOf obo:CIDO_0001157 . obo:PR_P15056 a rdfs:Class ; rdfs:label "serine/threonine-protein kinase B-raf (human)" ; rdfs:comment "A B-Raf proto-oncogene serine/threonine-protein kinase that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000004801 , obo:PR_000029067 . a rdfs:Class ; rdfs:label "Fatty Liver [Disease/Finding]" ; rdfs:subClassOf . a rdfs:Class ; rdfs:label "Sezary Syndrome [Disease/Finding]" ; rdfs:subClassOf . a rdfs:Class ; rdfs:label "Liver Neoplasms [Disease/Finding]" ; rdfs:subClassOf , . obo:CIDO_0000110 a rdfs:Class ; rdfs:label "modulation of host response to viral infection"@en ; rdfs:comment "A process that modulates host response to viral infection" ; rdfs:subClassOf obo:BFO_0000015 . obo:CHEBI_35610 a rdfs:Class ; rdfs:label "antineoplastic agent" ; rdfs:comment "A substance that inhibits or prevents the proliferation of neoplasms." ; rdfs:subClassOf obo:CHEBI_23888 . obo:PR_000001774 a rdfs:Class ; rdfs:label "inhibitor of nuclear factor kappa-B kinase complex alpha/beta subunits" ; rdfs:comment "A protein with core domain architecture consisting of an N-terminal Protein kinase domain (Pfam:PF00069), and a C-terminus that is involved in the interaction with NEMO (PR:000001752). In response to a large variety of stimuli, among them pro-inflammatory cytokines, growth factors and microbial pathogens, signals emanating from cell surface receptors converge at the IkappaB kinase (IKK) complex. This complex is composed of four subunits, IKKalpha, IKKbeta, ELK, and NEMO. IKKbeta and NEMO subunits are known to be essential for activating NF-kappaB. Activation of NF-kappaB dimers is the result of IKK-mediated, phosphorylation-induced degradation of the IkappaB inhibitor, which enables the NF-kappaB dimers to enter the nucleus and activate specific target gene expression." ; rdfs:subClassOf obo:PR_000000001 . obo:NCBITaxon_76804 a rdfs:Class ; rdfs:label "Nidovirales" ; rdfs:subClassOf obo:NCBITaxon_2559587 , obo:NCBITaxon_2732506 . a rdfs:Class ; rdfs:label "Intestinal Metabolism [PK]" ; rdfs:subClassOf . a rdfs:Class ; rdfs:label "Skin Diseases, Viral [Disease/Finding]" ; rdfs:subClassOf , obo:DOID_934 . a rdfs:Class ; rdfs:label "L [Preparations]" ; rdfs:subClassOf . obo:NCBITaxon_424367 a rdfs:Class ; rdfs:label "Bat coronavirus HKU9-1" ; rdfs:subClassOf obo:NCBITaxon_694006 . obo:PR_Q96N16 a rdfs:Class ; rdfs:label "Janus kinase and microtubule-interacting protein 1 (human)" ; rdfs:comment "A Janus kinase and microtubule-interacting protein 1 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000009199 , obo:PR_000029067 . obo:CHEBI_29340 a rdfs:Class ; rdfs:label "hydridonitrate(2-)" ; rdfs:comment "A divalent inorganic anion resulting from the removal of two protons from ammonia." ; rdfs:subClassOf obo:CHEBI_35106 , obo:CHEBI_79388 . obo:PR_000025875 a rdfs:Class ; rdfs:label "serpin" ; rdfs:comment "A protein that is primarily known as an irreversible serine protease inhibitor active against S1, S8 and C14 peptidases. There are both extra- and intra-cellular serpins, which are found in all groups of organisms with the notable exception of fungi. Serpin contains a copy of the Serpin (Pfam:PF00079) domain." ; rdfs:subClassOf obo:PR_000000001 . obo:NCBITaxon_249064 a rdfs:Class ; rdfs:label "SARS coronavirus GZ-C" ; rdfs:subClassOf obo:NCBITaxon_694009 . obo:CHEBI_11060 a rdfs:Class ; rdfs:label "(S)-carnitine" ; rdfs:comment "The (S)-enantiomer of carnitine." ; rdfs:subClassOf obo:CHEBI_17126 . obo:PR_Q7Z460 a rdfs:Class ; rdfs:label "CLIP-associating protein 1 (human)" ; rdfs:comment "A CLIP-associating protein 1 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000005520 , obo:PR_000029067 . a rdfs:Class ; rdfs:label "Photosensitivity Disorders [Disease/Finding]" ; rdfs:subClassOf . obo:NCBITaxon_1503302 a rdfs:Class ; rdfs:label "BtRs-BetaCoV/HuB2013" ; rdfs:subClassOf obo:NCBITaxon_694009 . obo:CIDO_0000288 a rdfs:Class ; rdfs:label "SARS-CoV shedding"@en ; rdfs:subClassOf obo:CIDO_0000202 . obo:UBERON_0001723 a rdfs:Class ; rdfs:label "tongue" ; rdfs:comment "A muscular organ in the floor of the mouth." ; rdfs:subClassOf obo:UBERON_0000465 . obo:PR_Q7Z2K6 a rdfs:Class ; rdfs:label "endoplasmic reticulum metallopeptidase 1 (human)" ; rdfs:comment "An endoplasmic reticulum metallopeptidase 1 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000007184 , obo:PR_000029067 . obo:CHEBI_32761 a rdfs:Class ; rdfs:label "L-tyrosinate(2-)" ; rdfs:comment "The L-enantiomer of tyrosinate(2-)." ; rdfs:subClassOf obo:CHEBI_32785 . a rdfs:Class ; rdfs:label "Chlamydiaceae Infections [Disease/Finding]" ; rdfs:subClassOf . obo:CHEBI_46774 a rdfs:Class ; rdfs:label "polyether" ; rdfs:comment "Any ether that contains more than one ether linkage." ; rdfs:subClassOf obo:CHEBI_25698 . obo:OBI_0002574 a rdfs:Class ; rdfs:label "RNA extraction with polyA depletion" ; rdfs:comment "A RNA extraction process in which only RNAs lacking a polyA tail are retained" ; rdfs:subClassOf obo:OBI_0666666 . a rdfs:Class ; rdfs:label "Steroid Hormone Receptor Agonists [MoA]" ; rdfs:subClassOf . obo:PR_000029138 a rdfs:Class ; rdfs:label "uncharacterized serine/threonine-protein kinase SBK3" ; rdfs:comment "A protein that is a translation product of the human SBK3 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:CHEBI_15778 a rdfs:Class ; rdfs:label "N-acyl-D-amino acid" ; rdfs:comment "Any N-acyl-amino acid in which the amino acid moiety has D configuration." ; rdfs:subClassOf obo:CHEBI_51569 , obo:CHEBI_83812 . obo:CHEBI_37962 a rdfs:Class ; rdfs:label "adrenergic agent" ; rdfs:comment "Any agent that acts on an adrenergic receptor or affects the life cycle of an adrenergic transmitter." ; rdfs:subClassOf obo:CHEBI_35942 . obo:PR_000036195 a rdfs:Class ; rdfs:label "bacterial protein" ; rdfs:comment "A protein that is encoded in the genome of some Bacteria ." ; rdfs:subClassOf obo:PR_000000001 . obo:NCBITaxon_903594 a rdfs:Class ; rdfs:label "Kenya bat coronavirus BtKY56" ; rdfs:subClassOf obo:NCBITaxon_2664420 . a rdfs:Class ; rdfs:label "Decreased Immunologically Active Biogenic Amine Degradation [PE]" ; rdfs:subClassOf . obo:NCBITaxon_1346306 a rdfs:Class ; rdfs:label "Betacoronavirus BtCoV/Rhi_fer/It2/ITA/2009" ; rdfs:subClassOf obo:NCBITaxon_696098 . obo:CHEBI_15897 a rdfs:Class ; rdfs:label "N-(long-chain-acyl)ethanolamine" ; rdfs:comment "Any N-acylethanolamine in which the acyl group has a chain length of C12 or greater." ; rdfs:subClassOf obo:CHEBI_167098 . obo:CHEBI_35875 a rdfs:Class ; rdfs:label "imidazopyrimidine" ; rdfs:subClassOf obo:CHEBI_27171 , obo:CHEBI_33833 , obo:CHEBI_38101 . obo:CHEBI_50338 a rdfs:Class ; rdfs:label "1H-imidazol-4-ylmethyl group" ; rdfs:subClassOf obo:CHEBI_50325 . obo:OAE_0003691 a rdfs:Class ; rdfs:label "Grade 2 myocarditis AE" ; rdfs:comment "a myocarditis AE that has symptoms with mild to moderate activity or exertion" ; rdfs:subClassOf obo:OAE_0001201 . obo:CHEBI_41879 a rdfs:Class ; rdfs:label "dexamethasone" ; rdfs:comment "A fluorinated steroid that is 9-fluoropregna-1,4-diene substituted by hydroxy groups at positions 11, 17 and 21, a methyl group at position 16 and oxo groups at positions 3 and 20. It is a synthetic member of the class of glucocorticoids." ; rdfs:subClassOf obo:CHEBI_24261 , obo:CHEBI_35342 , obo:CHEBI_35344 , obo:CHEBI_35346 , obo:CHEBI_36885 , obo:CHEBI_50830 , obo:CHEBI_77166 . obo:GO_0006939 a rdfs:Class ; rdfs:label "smooth muscle contraction" ; rdfs:comment "A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. Smooth muscle differs from striated muscle in the much higher actin/myosin ratio, the absence of conspicuous sarcomeres and the ability to contract to a much smaller fraction of its resting length." ; rdfs:subClassOf obo:GO_0006936 . obo:UBERON_0002385 a rdfs:Class ; rdfs:label "muscle tissue" ; rdfs:comment "Muscle tissue is a contractile tissue made up of actin and myosin fibers[GO]." ; rdfs:subClassOf obo:UBERON_0004120 , obo:UBERON_0010000 . obo:NCBITaxon_389135 a rdfs:Class ; rdfs:label "Bat coronavirus (BtCoV/A535/2005)" ; rdfs:subClassOf obo:NCBITaxon_389126 . obo:NCBITaxon_1269308 a rdfs:Class ; rdfs:label "Coronavirus BtCoV/KCR370/Pte_par/CRC/2011" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:CHEBI_24860 a rdfs:Class ; rdfs:label "iodine molecular entity" ; rdfs:subClassOf obo:CHEBI_24471 . obo:NCBITaxon_1477412 a rdfs:Class ; rdfs:label "Deltacoronavirus PDCoV/USA/Illinois134/2014" ; rdfs:subClassOf obo:NCBITaxon_1159905 . a rdfs:Class ; rdfs:label "Multiple Sclerosis [Disease/Finding]" ; rdfs:subClassOf . obo:NCBITaxon_2050018 a rdfs:Class ; rdfs:label "Rodent coronavirus" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:NCBITaxon_11139 a rdfs:Class ; rdfs:label "Murine hepatitis virus strain 1" ; rdfs:subClassOf obo:NCBITaxon_11138 . obo:GO_0035725 a rdfs:Class ; rdfs:label "sodium ion transmembrane transport" ; rdfs:comment "A process in which a sodium ion is transported from one side of a membrane to the other by means of some agent such as a transporter or pore." ; rdfs:subClassOf obo:GO_0030001 , obo:GO_0098662 . obo:PR_Q16620 a rdfs:Class ; rdfs:label "BDNF/NT-3 growth factors receptor (human)" ; rdfs:comment "A BDNF/NT-3 growth factors receptor that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000011470 , obo:PR_000029067 . obo:NCBITaxon_903604 a rdfs:Class ; rdfs:label "Kenya bat coronavirus BtKY66" ; rdfs:subClassOf obo:NCBITaxon_2664420 . a rdfs:Class ; rdfs:label "Hormone Receptor Interactions [MoA]" ; rdfs:subClassOf . obo:OGMS_0000063 a rdfs:Class ; rdfs:label "disease course" ; rdfs:comment "The totality of all processes through which a given disease instance is realized."@en ; rdfs:subClassOf obo:BFO_0000015 . obo:CHEBI_39142 a rdfs:Class ; rdfs:label "Bronsted base" ; rdfs:comment "A molecular entity capable of accepting a hydron from a donor (Bronsted acid)." ; rdfs:subClassOf obo:CHEBI_15339 , obo:CHEBI_22695 . obo:CHEBI_38106 a rdfs:Class ; rdfs:label "organosulfur heterocyclic compound" ; rdfs:subClassOf obo:CHEBI_24532 , obo:CHEBI_33261 . obo:NCBITaxon_1964806 a rdfs:Class ; rdfs:label "Coronavirus AcCoV-JC34" ; rdfs:subClassOf obo:NCBITaxon_2724758 . obo:GO_1903963 a rdfs:Class ; rdfs:label "arachidonate transport" ; rdfs:comment "The directed movement of an arachidonate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." ; rdfs:subClassOf obo:GO_0046942 , obo:GO_0071702 , obo:GO_0071715 . obo:PR_P0DTD1 a rdfs:Class . obo:PR_P07949 a rdfs:Class ; rdfs:label "proto-oncogene tyrosine-protein kinase receptor Ret (human)" ; rdfs:comment "A proto-oncogene tyrosine-protein kinase receptor Ret that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000013895 , obo:PR_000029067 . a rdfs:Class ; rdfs:label "Flaviviridae Infections [Disease/Finding]" ; rdfs:subClassOf . obo:VO_0000135 a rdfs:Class ; rdfs:label "vaccine-induced adaptive immune response" ; rdfs:subClassOf obo:VO_0000287 . obo:NCBITaxon_1503285 a rdfs:Class ; rdfs:label "BtMf-AlphaCoV/HeN2013-b" ; rdfs:subClassOf obo:NCBITaxon_366617 . obo:PR_000001967 a rdfs:Class ; rdfs:label "TEC-type tyrosine-protein kinase" ; rdfs:comment "A protein with core architecture consisting of a PH domain (Pfam:PF00169), a BTK-type zinc finger (Pfam:PF00779), an SH3 domain (Pfam:PF00018, an SH2 domain (Pfam:PF00017), and a Protein typrosine kinase domain (Pfam:PF07714)." ; rdfs:subClassOf obo:PR_000000001 . obo:PR_000001394 a rdfs:Class ; rdfs:label "interleukin-6 receptor subunit alpha" ; rdfs:comment "A protein that is a translation product of the human IL6R gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:CIDO_0020043 a rdfs:Class ; rdfs:label "BD SARS-CoV-2Reagents for BD MAX System" ; rdfs:seeAlso ; rdfs:subClassOf obo:CIDO_0000454 . obo:PR_O00750 a rdfs:Class ; rdfs:label "phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta (human)" ; rdfs:comment "A phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000012716 , obo:PR_000029067 . obo:OBI_0100017 a rdfs:Class ; rdfs:label "blood serum specimen"@en ; rdfs:comment "A material entity which derives from blood and corresponds to blood plasma without fibrinogen or the other clotting factors."@en ; rdfs:subClassOf obo:OBI_0000953 . a rdfs:Class ; rdfs:label "Pain [Disease/Finding]" ; rdfs:subClassOf . obo:PR_000001808 a rdfs:Class ; rdfs:label "C/C-C motif small inducible chemokine" ; rdfs:comment "A protein with core architecture consisting of a Small cytokines (intecrine/chemokine), interleukin-8 like (Pfam:PF00048) domain." ; rdfs:subClassOf obo:PR_000000001 . obo:PR_000015188 a rdfs:Class ; rdfs:label "sodium-dependent dopamine transporter" ; rdfs:comment "A protein that is a translation product of the human SLC6A3 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:CIDO_0000947 a rdfs:Class ; rdfs:label "SARS-CoV2 nsp9 protein binding to human DCAF7" ; rdfs:comment "SARS-CoV2 nsp9 protein binding to human DCAF7, as evidented by an affinity-purification mass spectrometry experiment" ; rdfs:subClassOf obo:CIDO_0000583 . obo:OBI_0002506 a rdfs:Class ; rdfs:label "pericardial fluid specimen" ; rdfs:comment "A specimen that is derived from pericardial fluid." ; rdfs:subClassOf obo:OBI_2000009 . obo:GO_0048008 a rdfs:Class ; rdfs:label "platelet-derived growth factor receptor signaling pathway" ; rdfs:comment "The series of molecular signals initiated by a ligand binding to a platelet-derived growth factor receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription." ; rdfs:subClassOf obo:GO_0007169 . obo:CIDO_0020190 a rdfs:Class ; rdfs:label "Lucira COVID-19 All-In-One Test Kit" ; rdfs:seeAlso ; rdfs:subClassOf obo:CIDO_0000454 . obo:CIDO_0000818 a rdfs:Class ; rdfs:label "SARS-CoV2 nsp12 protein binding to human UBAP2" ; rdfs:comment "SARS-CoV2 nsp12 protein binding to human UBAP2, as evidented by an affinity-purification mass spectrometry experiment" ; rdfs:subClassOf obo:CIDO_0000057 . obo:GO_0007188 a rdfs:Class ; rdfs:label "adenylate cyclase-modulating G protein-coupled receptor signaling pathway" ; rdfs:comment "A G protein-coupled receptor signaling pathway in which the signal is transmitted via the activation or inhibition of adenylyl cyclase activity and a subsequent change in the intracellular concentration of cyclic AMP (cAMP)." ; rdfs:subClassOf obo:GO_0007186 . obo:DRON_00000020 a rdfs:Class ; rdfs:label "drug solution"@en ; rdfs:comment "a portion of solution that is the bearer of a clinical drug role"@en ; rdfs:subClassOf obo:DRON_00000007 . obo:VO_0005191 a rdfs:Class ; rdfs:label "MVA-SARS-2-S"@en ; rdfs:comment "A SARS-CoV-2 recombinant vector vaccine that contains a Modified Vaccinia Virus Ankara (MVA) vector expressing the SARS-CoV-2 spike protein (S)" ; rdfs:subClassOf obo:VO_0005199 . obo:GO_0051223 a rdfs:Class ; rdfs:label "regulation of protein transport" ; rdfs:comment "Any process that modulates the frequency, rate or extent of the directed movement of a protein into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." ; rdfs:subClassOf obo:GO_0051049 , obo:GO_0070201 . obo:CHEBI_50699 a rdfs:Class ; rdfs:label "oligosaccharide" ; rdfs:comment "A compound in which monosaccharide units are joined by glycosidic linkages. The term is commonly used to refer to a defined structure as opposed to a polymer of unspecified length or a homologous mixture. When the linkages are of other types the compounds are regarded as oligosaccharide analogues." ; rdfs:subClassOf obo:CHEBI_16646 , obo:CHEBI_167559 . obo:GO_0051282 a rdfs:Class ; rdfs:label "regulation of sequestering of calcium ion" ; rdfs:comment "Any process that modulates the frequency, rate or extent of the binding or confining calcium ions such that they are separated from other components of a biological system." ; rdfs:subClassOf obo:GO_0032879 , obo:GO_0050794 . obo:CIDO_0000541 a rdfs:Class ; rdfs:label "SFFEDLLFDKVKLSD" ; rdfs:comment "A coronavirus epitope that is part of some S protein from HCoV HKU1 composed of the following amino acids SFFEDLLFDKVKLSD" ; rdfs:subClassOf obo:CIDO_0000409 . obo:NCBITaxon_1679899 a rdfs:Class ; rdfs:label "Coronavirus RCoV/D_RMU10_2089/Myo_gla/GER/2010" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:NCBITaxon_903568 a rdfs:Class ; rdfs:label "Kenya bat coronavirus BtKY100" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:CIDO_0000027 a rdfs:Class ; rdfs:label "COVID-19 diagnostic process by viral genome sequencing"@en ; rdfs:comment "A COVID-19 diagnostic process by viral genome sequencing and identification of the SARS-CoV-2 based on the genome sequence." ; rdfs:subClassOf obo:CIDO_0000424 . obo:GO_0005245 a rdfs:Class ; rdfs:label "voltage-gated calcium channel activity" ; rdfs:comment "Enables the transmembrane transfer of a calcium ion by a voltage-gated channel. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded." ; rdfs:subClassOf obo:GO_0005262 , obo:GO_0022843 . a rdfs:Class ; rdfs:label "Sebaceous Gland Diseases [Disease/Finding]" ; rdfs:subClassOf . obo:PR_000010845 a rdfs:Class ; rdfs:label "myosin light chain kinase, smooth muscle" ; rdfs:comment "A protein that is a translation product of the human MYLK gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:OBCS_0000058 a rdfs:Class ; rdfs:label "sensitivity" ; rdfs:comment "A data item that measures the proportion of actual positives which are correctly identified as such (e.g. the percentage of sick people who are correctly identified as having the condition). " ; rdfs:subClassOf obo:OBCS_0000220 . obo:NCBITaxon_497929 a rdfs:Class ; rdfs:label "Bat coronavirus M.das/Germany/D2.2/2007" ; rdfs:subClassOf obo:NCBITaxon_366617 . obo:PR_Q02156 a rdfs:Class ; rdfs:label "protein kinase C epsilon type (human)" ; rdfs:comment "A protein kinase C epsilon that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000002342 , obo:PR_000029067 . obo:PR_P25440 a rdfs:Class ; rdfs:label "bromodomain-containing protein 2 (human)" ; rdfs:comment "A bromodomain-containing protein 2 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000004806 , obo:PR_000029067 . obo:PR_000005501 a rdfs:Class ; rdfs:label "CDGSH iron-sulfur domain-containing protein 1" ; rdfs:comment "A protein that is a translation product of the human CISD1 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:PR_000007262 a rdfs:Class ; rdfs:label "exosome complex component RRP46" ; rdfs:comment "A protein that is a translation product of the human EXOSC5 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:DOID_4 a rdfs:Class ; rdfs:label "disease" ; rdfs:comment "A disease is a disposition (i) to undergo pathological processes that (ii) exists in an organism because of one or more disorders in that organism." ; rdfs:subClassOf obo:OGMS_0000031 . obo:HP_0031677 a rdfs:Class ; rdfs:label "Polymorphic ventricular tachycardia" ; rdfs:comment "A type of ventricular tachycardia that is characterized by variable QRS complexes within each lead (i.e., QRS complexes may be different from beat to beat)." ; rdfs:subClassOf obo:HP_0004756 . obo:CIDO_0020208 a rdfs:Class ; rdfs:label "Nationwide Children’s Hospital SARS-CoV-2 Assay" ; rdfs:seeAlso ; rdfs:subClassOf obo:CIDO_0000454 . a rdfs:Class ; rdfs:label "Vascular Permeability Alteration [PE]" ; rdfs:subClassOf . obo:CHEBI_26767 a rdfs:Class ; rdfs:label "steroid alkaloid" ; rdfs:subClassOf obo:CHEBI_22315 , obo:CHEBI_35341 . obo:CIDO_0001153 a rdfs:Class ; rdfs:label "R203K in SARS-CoV-2 N protein"@en ; rdfs:subClassOf obo:CIDO_0000597 . obo:NCBITaxon_2726811 a rdfs:Class ; rdfs:label "unclassified Nobecovirus" ; rdfs:subClassOf obo:NCBITaxon_2509502 . obo:CHEBI_77019 a rdfs:Class ; rdfs:label "EC 1.10.99.* (oxidoreductases acting on diphenols and related substances as donors, other acceptors) inhibitor" ; rdfs:comment "An EC 1.10.* (oxidoreductase acting on diphenols and related substances as donors) inhibitor that interferes with the action of any such enzyme in the EC 1.10.99.* category." ; rdfs:subClassOf obo:CHEBI_76737 . obo:HP_0030680 a rdfs:Class ; rdfs:label "Abnormality of cardiovascular system morphology" ; rdfs:comment "Any structural anomaly of the heart and great vessels." ; rdfs:subClassOf obo:HP_0001626 . obo:NCBITaxon_441983 a rdfs:Class ; rdfs:label "Siberian weasel coronavirus Guangxi/D1000/2006" ; rdfs:subClassOf obo:NCBITaxon_441985 . a rdfs:Class ; rdfs:label "Methylergonovine [Chemical/Ingredient]" ; rdfs:subClassOf . obo:DOID_0081012 a rdfs:Class ; rdfs:label "critical COVID-19"@en ; rdfs:comment "A COVID-19 that is characterized by the criteria for acute respiratory distress syndrome (ARDS), sepsis, septic shock, or other conditions that would normally require the provision of life sustaining therapies such as mechanical ventilation (invasive or non-invasive) or vasopressor therapy." ; rdfs:subClassOf obo:DOID_0080600 . obo:VO_0005163 a rdfs:Class ; rdfs:label "Sputnik V" ; rdfs:comment "A SARS-CoV-2 recombinant viral vector vaccine composed of Ad26 and Ad5 vectors expressing S protein that lyophilised." ; rdfs:subClassOf obo:VO_0005268 . obo:CHEBI_20702 a rdfs:Class ; rdfs:label "2-aminopurines" ; rdfs:comment "Any aminopurine having the amino substituent at the 2-position." ; rdfs:subClassOf obo:CHEBI_22527 . obo:CIDO_0000479 a rdfs:Class ; rdfs:label "CVQSYKGIKVLPPLL" ; rdfs:comment "A coronavirus epitope that is part of some S protein from HCoV OC43 composed of the following amino acids CVQSYKGIKVLPPLL" ; rdfs:subClassOf obo:CIDO_0000452 . obo:PR_Q8TAD8 a rdfs:Class ; rdfs:label "smad nuclear-interacting protein 1 (human)" ; rdfs:comment "A smad nuclear-interacting protein 1 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000015328 , obo:PR_000029067 . obo:PR_000014020 a rdfs:Class ; rdfs:label "serine/threonine-protein kinase RIO2" ; rdfs:comment "A protein that is a translation product of the human RIOK2 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . a rdfs:Class ; rdfs:label "Quinidine [Chemical/Ingredient]" ; rdfs:subClassOf , , . obo:NCBITaxon_11144 a rdfs:Class ; rdfs:label "Murine hepatitis virus strain JHM" ; rdfs:subClassOf obo:NCBITaxon_11138 . obo:CHEBI_33257 a rdfs:Class ; rdfs:label "secondary amide" ; rdfs:comment "A derivative of two oxoacids RkE(=O)l(OH)m (l =/= 0) in which two acyl groups are attached to the amino or substituted amino group." ; rdfs:subClassOf obo:CHEBI_32988 . obo:PR_000008883 a rdfs:Class ; rdfs:label "serine/threonine-protein kinase ICK" ; rdfs:comment "A protein that is a translation product of the human CILK1 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:PR_Q05318 a rdfs:Class ; rdfs:label "RNA-directed RNA polymerase L (Zaire Ebola virus)" ; rdfs:comment "A protein from Zaire ebolavirus (strain Mayinga-76)." ; rdfs:subClassOf obo:PR_000000001 . obo:PR_000011357 a rdfs:Class ; rdfs:label "NPC intracellular cholesterol transporter 2" ; rdfs:comment "A protein that is a translation product of the human NPC2 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:NCBITaxon_1429859 a rdfs:Class ; rdfs:label "Betacoronavirus Pipistrellus kuhlii/Italy/206645-53/2011" ; rdfs:subClassOf obo:NCBITaxon_696098 . a rdfs:Class ; rdfs:label "Lysosomal Function Alteration [PE]" ; rdfs:subClassOf . obo:GO_0044248 a rdfs:Class ; rdfs:label "cellular catabolic process" ; rdfs:comment "The chemical reactions and pathways resulting in the breakdown of substances, carried out by individual cells." ; rdfs:subClassOf obo:GO_0009056 , obo:GO_0044237 . obo:CHEBI_47909 a rdfs:Class ; rdfs:label "3-oxo-Delta(4) steroid" ; rdfs:comment "A 3-oxo steroid conjugated to a C=C double bond at the alpha,beta position." ; rdfs:subClassOf obo:CHEBI_47788 , obo:CHEBI_51689 . a rdfs:Class ; rdfs:label "Azithromycin [Chemical/Ingredient]" ; rdfs:subClassOf . obo:PR_P20839 a rdfs:Class ; rdfs:label "inosine-5'-monophosphate dehydrogenase 1 (human)" ; rdfs:comment "An inosine-5'-monophosphate dehydrogenase 1 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000009021 , obo:PR_000029067 . a rdfs:Class ; rdfs:label "Mycoplasmatales Infections [Disease/Finding]" ; rdfs:subClassOf . obo:CHEBI_23982 a rdfs:Class ; rdfs:label "ethanols" ; rdfs:comment "Any primary alcohol based on an ethanol skeleton." ; rdfs:subClassOf obo:CHEBI_15734 . obo:CIDO_0000734 a rdfs:Class ; rdfs:label "SARS-CoV2 E protein binding to human ZC3H18" ; rdfs:comment "SARS-CoV2 E protein binding to human ZC3H18, as evidented by an affinity-purification mass spectrometry experiment" ; rdfs:subClassOf obo:CIDO_0000046 . obo:CHEBI_25741 a rdfs:Class ; rdfs:label "oxide" ; rdfs:comment "An oxide is a chemical compound of oxygen with other chemical elements." ; rdfs:subClassOf obo:CHEBI_25806 , obo:CHEBI_37577 . obo:VO_0005123 a rdfs:Class ; rdfs:label "VSVΔG-MERS vaccine" ; rdfs:comment "A MERS recombinant vector virus made from chimeric virus based on the vesicular stomatitis virus (VSV) in which the G gene was replaced by MERS-CoV S gene (VSVΔG-MERS)." ; rdfs:subClassOf obo:VO_0004900 . obo:CHEBI_35604 a rdfs:Class ; rdfs:label "carbon oxoanion" ; rdfs:comment "A negative ion consisting solely of carbon and oxygen atoms, and therefore having the general formula CxOy(n-) for some integers x, y and n." ; rdfs:subClassOf obo:CHEBI_25696 , obo:CHEBI_35406 , obo:CHEBI_36963 . obo:PR_P43403 a rdfs:Class ; rdfs:label "tyrosine-protein kinase ZAP-70 (human)" ; rdfs:comment "A tyrosine-protein kinase ZAP-70 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000003064 , obo:PR_000029067 . a rdfs:Class ; rdfs:label "Chloroquine [Chemical/Ingredient]" ; rdfs:subClassOf . obo:CHEBI_48927 a rdfs:Class ; rdfs:label "N-acyl-L-alpha-amino acid" ; rdfs:comment "Any L-alpha-amino acid carrying an N-acyl substituent." ; rdfs:subClassOf obo:CHEBI_21644 . obo:DRON_00012840 a rdfs:Class ; rdfs:label "digoxin antibodies Fab fragments" ; rdfs:subClassOf obo:OBI_0000047 . obo:CHEBI_51374 a rdfs:Class ; rdfs:label "GABA agent" ; rdfs:comment "A substance, such as agonists, antagonists, degradation or uptake inhibitors, depleters, precursors, and modulators of receptor function, used for its pharmacological actions on GABAergic systems." ; rdfs:subClassOf obo:CHEBI_35942 . obo:CHEBI_38637 a rdfs:Class ; rdfs:label "tyrosine kinase inhibitor" ; rdfs:comment "Any protein kinase inhibitor that interferes with the action of tyrosine kinase." ; rdfs:subClassOf obo:CHEBI_37699 . obo:CHEBI_77450 a rdfs:Class ; rdfs:label "dicarboxylic acid monoamide(1-)" ; rdfs:comment "A monocarboxylic acid anion obtained by deprotonation of the carboxy group of any dicarboxylic acid monoamide; major species at pH 7.3." ; rdfs:subClassOf obo:CHEBI_35757 . obo:OBI_0002528 a rdfs:Class ; rdfs:label "stomach specimen" ; rdfs:comment "A specimen that is derived from stomach." ; rdfs:subClassOf obo:OBI_0001479 . obo:CIDO_0020003 a rdfs:Class ; rdfs:label "Access SARS-CoV-2 IgG" ; rdfs:seeAlso ; rdfs:subClassOf obo:CIDO_0000454 . a rdfs:Class ; rdfs:label "Ergolines [Chemical/Ingredient]" ; rdfs:subClassOf , . obo:CHEBI_22720 a rdfs:Class ; rdfs:label "benzodiazepine" ; rdfs:comment "A group of heterocyclic compounds with a core structure containing a benzene ring fused to a diazepine ring." ; rdfs:subClassOf obo:CHEBI_38101 , obo:CHEBI_38166 . obo:CIDO_0000468 a rdfs:Class ; rdfs:label "AWYFLAMLTGLLPSL" ; rdfs:comment "A coronavirus epitope that is part of some S protein from HCoV 229E composed of the following amino acids AWYFLAMLTGLLPSL" ; rdfs:subClassOf obo:CIDO_0000451 . obo:VO_0000585 a rdfs:Class ; rdfs:label "immunization objective" ; rdfs:comment "immunization objective is the specification of an objective to achieve immunization." ; rdfs:subClassOf obo:IAO_0000005 . obo:CHEBI_48001 a rdfs:Class ; rdfs:label "protein synthesis inhibitor" ; rdfs:comment "A compound, usually an anti-bacterial agent or a toxin, which inhibits the synthesis of a protein." ; rdfs:subClassOf obo:CHEBI_76932 . obo:GO_0048522 a rdfs:Class ; rdfs:label "positive regulation of cellular process" ; rdfs:comment "Any process that activates or increases the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level." ; rdfs:subClassOf obo:GO_0048518 , obo:GO_0050794 . obo:PR_000013231 a rdfs:Class ; rdfs:label "cAMP-dependent protein kinase type II-beta regulatory subunit" ; rdfs:comment "A protein that is a translation product of the human PRKAR2B gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:CHEBI_50366 a rdfs:Class ; rdfs:label "6-methylprednisolone" ; rdfs:comment "A 3-oxo steroid that has formula C22H30O5." ; rdfs:subClassOf obo:CHEBI_139590 , obo:CHEBI_139592 , obo:CHEBI_35342 , obo:CHEBI_35344 , obo:CHEBI_35346 , obo:CHEBI_36885 , obo:CHEBI_47788 , obo:CHEBI_77166 . obo:NCBITaxon_1525377 a rdfs:Class ; rdfs:label "Porcine epidemic diarrhea virus L00721/GER/2014" ; rdfs:subClassOf obo:NCBITaxon_28295 . obo:CIDO_0000016 a rdfs:Class ; rdfs:label "COVID-19 diagnostic objective"@en ; rdfs:subClassOf obo:CIDO_0000015 . obo:UBERON_0002107 a rdfs:Class ; rdfs:label "liver" ; rdfs:comment "An exocrine gland which secretes bile and functions in metabolism of protein and carbohydrate and fat, synthesizes substances involved in the clotting of the blood, synthesizes vitamin A, detoxifies poisonous substances, stores glycogen, and breaks down worn-out erythrocytes[GO]." ; rdfs:subClassOf obo:UBERON_0000465 . obo:OMIABIS_0000052 a rdfs:Class ; rdfs:label "fixed tissue slide specimen"@en ; rdfs:comment "A fixed tissue specimen that is placed in a slide."@en ; rdfs:subClassOf obo:OMIABIS_0000050 . obo:NCBITaxon_1289556 a rdfs:Class ; rdfs:label "coronavirus Mex_CoV-11b" ; rdfs:subClassOf obo:NCBITaxon_696098 . obo:CIDO_0020040 a rdfs:Class ; rdfs:label "BayCare SARS-CoV-2 RT PCR Assay" ; rdfs:seeAlso ; rdfs:subClassOf obo:CIDO_0000454 . obo:CIDO_0020264 a rdfs:Class ; rdfs:label "Rheonix COVID-19 MDx Assay" ; rdfs:seeAlso ; rdfs:subClassOf obo:CIDO_0000454 . obo:GO_0007626 a rdfs:Class ; rdfs:label "locomotory behavior" ; rdfs:comment "The specific movement from place to place of an organism in response to external or internal stimuli. Locomotion of a whole organism in a manner dependent upon some combination of that organism's internal state and external conditions." ; rdfs:subClassOf obo:GO_0007610 . obo:OPMI_0000475 a rdfs:Class ; rdfs:label "birth datetime"@en ; rdfs:comment "The date and time of birth of a person." ; rdfs:subClassOf obo:OPMI_0000478 . obo:CIDO_0000908 a rdfs:Class ; rdfs:label "SARS-CoV2 nsp7 protein binding to human QSOX2" ; rdfs:comment "SARS-CoV2 nsp7 protein binding to human QSOX2, as evidented by an affinity-purification mass spectrometry experiment" ; rdfs:subClassOf obo:CIDO_0000049 . obo:PR_000015752 a rdfs:Class ; rdfs:label "serine/threonine-protein kinase 35" ; rdfs:comment "A protein that is a translation product of the human STK35 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:PR_P48556 a rdfs:Class ; rdfs:label "26S proteasome non-ATPase regulatory subunit 8 (human)" ; rdfs:comment "A 26S proteasome non-ATPase regulatory subunit 8 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000013390 , obo:PR_000029067 . obo:PR_000006311 a rdfs:Class ; rdfs:label "serine/threonine-protein kinase DCLK2" ; rdfs:comment "A doublecortin-like kinase that is a translation product of the human DCLK2 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000050059 . obo:NCBITaxon_429330 a rdfs:Class ; rdfs:label "Murine coronavirus repJHM/RA59" ; rdfs:subClassOf obo:NCBITaxon_11138 . a rdfs:Class ; rdfs:label "Hydroxychloroquine [Chemical/Ingredient]" ; rdfs:subClassOf . obo:CHEBI_32852 a rdfs:Class ; rdfs:label "L-valinium" ; rdfs:comment "The L-enantiomer of valinium." ; rdfs:subClassOf obo:CHEBI_32860 . obo:GO_0070302 a rdfs:Class ; rdfs:label "regulation of stress-activated protein kinase signaling cascade" ; rdfs:comment "Any process that modulates the frequency, rate or extent of signaling via a stress-activated protein kinase signaling cascade." ; rdfs:subClassOf obo:GO_0080135 , obo:GO_1902531 . obo:CHEBI_18154 a rdfs:Class ; rdfs:label "polysaccharide" ; rdfs:comment "A biomacromolecule consisting of large numbers of monosaccharide residues linked glycosidically. This term is commonly used only for those containing more than ten monosaccharide residues." ; rdfs:subClassOf obo:CHEBI_16646 , obo:CHEBI_167559 , obo:CHEBI_33694 . a rdfs:Class ; rdfs:label "Teicoplanin [Chemical/Ingredient]" ; rdfs:subClassOf . obo:CIDO_0000436 a rdfs:Class ; rdfs:label "motivation of survival"@en ; rdfs:comment "A movitation for survival in a specific environment" ; rdfs:subClassOf obo:CIDO_0000434 . obo:CHEBI_189679 a rdfs:Class ; rdfs:label "BRD proteins degrader" ; rdfs:comment "Protein degraders tackle tough drug targets by hijacking a cell's natural system for disposing of spent or misfolded proteins" ; rdfs:subClassOf obo:CHEBI_50860 . a rdfs:Class ; rdfs:label "Cardiovascular Activity Alteration [PE]" ; rdfs:subClassOf . obo:CIDO_0020297 a rdfs:Class ; rdfs:label "Sofia 2 Flu + SARS Antigen FIA" ; rdfs:seeAlso ; rdfs:subClassOf obo:CIDO_0000454 . obo:NCBITaxon_2421386 a rdfs:Class ; rdfs:label "Feline alphacoronavirus 1" ; rdfs:subClassOf obo:NCBITaxon_2727861 . obo:PR_000007087 a rdfs:Class ; rdfs:label "ectonucleotide pyrophosphatase/phosphodiesterase family member 1" ; rdfs:comment "A protein that is a translation product of the human ENPP1 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:PR_000005938 a rdfs:Class ; rdfs:label "tyrosine-protein kinase CSK" ; rdfs:comment "A proto-oncogene SRC-like tyrosine-protein kinase that is a translation product of the human CSK gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000002997 . obo:NCBITaxon_266147 a rdfs:Class ; rdfs:label "SARS coronavirus Sin0409" ; rdfs:subClassOf obo:NCBITaxon_694009 . obo:UBERON_0001728 a rdfs:Class ; rdfs:label "nasopharynx" ; rdfs:comment "the section of the pharynx that lies above the soft palate" ; rdfs:subClassOf obo:UBERON_0000465 . obo:NCBITaxon_384350 a rdfs:Class ; rdfs:label "Human coronavirus NO/0867/04" ; rdfs:subClassOf obo:NCBITaxon_384335 . obo:CHEBI_30096 a rdfs:Class ; rdfs:label "diazene" ; rdfs:subClassOf obo:CHEBI_35106 . obo:UBERON_0000479 a rdfs:Class ; rdfs:label "tissue" ; rdfs:comment "Multicellular anatomical structure that consists of many cells of one or a few types, arranged in an extracellular matrix such that their long-range organisation is at least partly a repetition of their short-range organisation." ; rdfs:subClassOf obo:UBERON_0000465 , obo:UBERON_0010000 . a rdfs:Class ; rdfs:label "Increased Lymphocyte Cell Destruction [PE]" ; rdfs:subClassOf . obo:VO_0005174 a rdfs:Class ; rdfs:label "bacTRL-Spike"@en ; rdfs:comment "A SARS-CoV-2 oral DNA vaccine that delivers plasmids containing synthetic DNA encoding spike protein from SARS-CoV-2." ; rdfs:subClassOf obo:VO_0005203 . obo:PR_Q9BSC4 a rdfs:Class ; rdfs:label "nucleolar protein 10 (human)" ; rdfs:comment "A nucleolar protein 10 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000011307 , obo:PR_000029067 . obo:CIDO_0000530 a rdfs:Class ; rdfs:label "NLLKQYTSACKTIED" ; rdfs:comment "A coronavirus epitope that is part of some S protein from HCoV NL63 composed of the following amino acids NLLKQYTSACKTIED" ; rdfs:subClassOf obo:CIDO_0000449 . obo:NCBITaxon_749437 a rdfs:Class ; rdfs:label "Rock sandpiper coronavirus CIR-665821" ; rdfs:subClassOf obo:NCBITaxon_749416 . obo:NCBITaxon_1511622 a rdfs:Class ; rdfs:label "Coronavirus BtCoV/E63/HUN/2013" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:PR_Q13224 a rdfs:Class ; rdfs:label "glutamate receptor ionotropic, NMDA 2B (human)" ; rdfs:comment "A glutamate receptor ionotropic, NMDA 2B that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000008247 , obo:PR_000029067 . obo:CIDO_0001000 a rdfs:Class ; rdfs:label "Galidesivir" ; rdfs:subClassOf obo:CHEBI_23367 . obo:CIDO_0000868 a rdfs:Class ; rdfs:label "SARS-CoV2 nsp15 protein binding to human RNF41" ; rdfs:comment "SARS-CoV2 nsp15 protein binding to human RNF41, as evidented by an affinity-purification mass spectrometry experiment" ; rdfs:subClassOf obo:CIDO_0000347 . obo:PR_000002062 a rdfs:Class ; rdfs:label "macrophage colony-stimulating factor 1 receptor" ; rdfs:comment "A CSF-1/PDGF receptor-type tyrosine-protein kinase that is a translation product of the human CSF1R gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000001810 . obo:VO_0005134 a rdfs:Class ; rdfs:label "MVvac2-MERS-N vaccine" ; rdfs:comment "A MERS recombinant vector vaccine made of live-attenuated measles virus (MV) vaccine encoding the MERS-CoV nucleocapsid protein (MERS-N)." ; rdfs:subClassOf obo:VO_0004900 . obo:PR_000012876 a rdfs:Class ; rdfs:label "procollagen-lysine,2-oxoglutarate 5-dioxygenase 1" ; rdfs:comment "A protein that is a translation product of the human PLOD1 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:HP_0010978 a rdfs:Class ; rdfs:label "Abnormality of immune system physiology" ; rdfs:comment "A functional abnormality of the immune system." ; rdfs:subClassOf obo:HP_0002715 . obo:CIDO_0000587 a rdfs:Class ; rdfs:label "SARS-CoV-2 orf7a protein interaction with host protein"@en ; rdfs:comment "A molecular interaction that has participant of the SARS-CoV-2 orf7a protein and a host protein" ; rdfs:subClassOf obo:CIDO_0000348 . obo:NCBITaxon_2045491 a rdfs:Class ; rdfs:label "Swine enteric alphacoronavirus" ; rdfs:subClassOf obo:NCBITaxon_2691594 . obo:PR_Q6Y7W6 a rdfs:Class ; rdfs:label "GRB10-interacting GYF protein 2 (human)" ; rdfs:comment "A GRB10-interacting GYF protein 2 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000007977 , obo:PR_000029067 . obo:GO_0098655 a rdfs:Class ; rdfs:label "cation transmembrane transport" ; rdfs:comment "The process in which a cation is transported across a membrane." ; rdfs:subClassOf obo:GO_0006812 , obo:GO_0034220 . obo:VO_0005100 a rdfs:Class ; rdfs:label "SARS N protein DNA vaccine" ; rdfs:comment "'A SARS DNA vaccine that is made from recombinant plasmid containing nucleocapsid protein (N) sequence constructed then expressed and purified from E. coli bacteria’" ; rdfs:subClassOf obo:VO_0012183 . obo:CIDO_0000961 a rdfs:Class ; rdfs:label "SARS-CoV2 nsp9 protein binding to human SPART" ; rdfs:comment "SARS-CoV2 nsp9 protein binding to human SPART, as evidented by an affinity-purification mass spectrometry experiment" ; rdfs:subClassOf obo:CIDO_0000583 . obo:CHEBI_33247 a rdfs:Class ; rdfs:label "organic group" ; rdfs:comment "Any substituent group or skeleton containing carbon." ; rdfs:subClassOf obo:CHEBI_24433 . obo:OBI_0002553 a rdfs:Class ; rdfs:label "uterus specimen" ; rdfs:comment "A specimen that is derived from uterus." ; rdfs:subClassOf obo:OBI_0001479 . obo:CIDO_0000563 a rdfs:Class ; rdfs:label "VSATVLQNNELMPAK" ; rdfs:comment "A coronavirus epitope that is part of some S protein from HCoV OC43 composed of the following amino acids VSATVLQNNELMPAK" ; rdfs:subClassOf obo:CIDO_0000452 . obo:GO_0048583 a rdfs:Class ; rdfs:label "regulation of response to stimulus" ; rdfs:comment "Any process that modulates the frequency, rate or extent of a response to a stimulus. Response to stimulus is a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus." ; rdfs:subClassOf obo:GO_0050789 . obo:CHEBI_51269 a rdfs:Class ; rdfs:label "acenes" ; rdfs:comment "Polycyclic aromatic hydrocarbons consisting of fused benzene rings in a rectilinear arrangement and their substitution derivatives." ; rdfs:subClassOf obo:CHEBI_33836 . obo:PR_000004436 a rdfs:Class ; rdfs:label "sodium/potassium-transporting ATPase subunit alpha-2" ; rdfs:comment "A protein that is a translation product of the human ATP1A2 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:CHEBI_25355 a rdfs:Class ; rdfs:label "mitochondrial respiratory-chain inhibitor" ; rdfs:subClassOf obo:CHEBI_38497 . obo:OBI_0000924 a rdfs:Class ; rdfs:label "labeled specimen" ; rdfs:comment "A specimen that has been modified in order to be able to detect it in future experiments" ; rdfs:subClassOf obo:OBI_0000953 , obo:OBI_0001936 , obo:OBI_0100051 . obo:CHEBI_50370 a rdfs:Class ; rdfs:label "parasympatholytic" ; rdfs:comment "Any cholinergic antagonist that inhibits the actions of the parasympathetic nervous system. The major group of drugs used therapeutically for this purpose is the muscarinic antagonists." ; rdfs:subClassOf obo:CHEBI_48873 . obo:PR_P61916 a rdfs:Class ; rdfs:label "NPC intracellular cholesterol transporter 2 (human)" ; rdfs:comment "An NPC intracellular cholesterol transporter 2 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000011357 , obo:PR_000029067 . obo:PR_P29317 a rdfs:Class ; rdfs:label "ephrin type-A receptor 2 (human)" ; rdfs:comment "An ephrin type-A receptor 2 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000007122 , obo:PR_000029067 . obo:CIDO_0000790 a rdfs:Class ; rdfs:label "SARS-CoV2 N protein binding to human UPF1" ; rdfs:comment "SARS-CoV2 N protein binding to human UPF1, as evidented by an affinity-purification mass spectrometry experiment" ; rdfs:subClassOf obo:CIDO_0000056 . a rdfs:Class ; rdfs:label "Pyridines [Chemical/Ingredient]" ; rdfs:subClassOf . obo:CIDO_0000685 a rdfs:Class ; rdfs:label "P681H in SARS-CoV-2 S protein" ; rdfs:comment "An AA mutation or AA variant that has mutated an amino acid at position 681 into a histidine in S protein." ; rdfs:subClassOf obo:CIDO_0000592 . obo:OPMI_0000486 a rdfs:Class ; rdfs:label "emergency room visit"@en ; rdfs:comment "A vist ocurrence in which a patient attends an outpatient clinic with no plan to stay beyond the duration of the visit." ; rdfs:subClassOf obo:OPMI_0000482 . obo:NCBITaxon_240549 a rdfs:Class ; rdfs:label "SARS coronavirus TWH" ; rdfs:subClassOf obo:NCBITaxon_694009 . obo:NCBITaxon_160750 a rdfs:Class ; rdfs:label "Avian infectious bronchitis virus (strain Beaudette US)" ; rdfs:subClassOf obo:NCBITaxon_11120 . obo:CHEBI_176497 a rdfs:Class ; rdfs:label "geroprotector" ; rdfs:comment "Any compound that supports healthy aging, slows the biological aging process, or extends lifespan." ; rdfs:subClassOf obo:CHEBI_50267 . obo:DOID_10933 a rdfs:Class ; rdfs:label "obsessive-compulsive disorder" ; rdfs:comment "An anxiety disorder that involves unwanted and repeated thoughts, feelings, ideas, sensations (obsessions), or behaviors that make them feel driven to do something (compulsions)." ; rdfs:subClassOf obo:DOID_2030 . obo:NCBITaxon_903626 a rdfs:Class ; rdfs:label "Kenya bat coronavirus BtKY88" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:CHEBI_26607 a rdfs:Class ; rdfs:label "saturated fatty acid" ; rdfs:comment "Any fatty acid containing no carbon to carbon multiple bonds. Known to produce adverse biological effects when ingested to excess." ; rdfs:subClassOf obo:CHEBI_35366 . obo:PR_000029946 a rdfs:Class ; rdfs:label "glutathione S-transferase alpha" ; rdfs:comment "Category=family. Note: Classification described in wikipedia. [Wikipedia:Glutathione_S-transferase]" ; rdfs:subClassOf obo:PR_000029945 . a rdfs:Class ; rdfs:label "Hemorrhagic Disorders [Disease/Finding]" ; rdfs:subClassOf . obo:NCBITaxon_864621 a rdfs:Class ; rdfs:label "Bat coronavirus 1B BR98-19/BGR/2008" ; rdfs:subClassOf obo:NCBITaxon_366617 . obo:PR_P42574 a rdfs:Class ; rdfs:label "caspase-3 (human)" ; rdfs:comment "A caspase-3 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000002312 , obo:PR_000029067 . obo:NCBITaxon_2801854 a rdfs:Class ; rdfs:label "Bat coronavirus RacCS264" ; rdfs:subClassOf obo:NCBITaxon_1986197 . obo:PR_000001115 a rdfs:Class ; rdfs:label "alpha-1 adrenergic receptor" ; rdfs:comment "An adrenoceptor protein whose active form binds adrenaline and related compounds and whose activity is mediated by G proteins that activate a phosphatidylinositol-calcium second messenger system." ; rdfs:subClassOf obo:PR_000044631 . obo:NCBITaxon_2691576 a rdfs:Class ; rdfs:label "Coronavirus PREDICT CoV-85" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:CHEBI_18367 a rdfs:Class ; rdfs:label "phosphate(3-)" ; rdfs:comment "A phosphate ion that is the conjugate base of hydrogenphosphate." ; rdfs:subClassOf obo:CHEBI_35780 , obo:CHEBI_79387 . obo:DRON_00018693 a rdfs:Class ; rdfs:label "imatinib" ; rdfs:subClassOf obo:OBI_0000047 . obo:PR_000029187 a rdfs:Class ; rdfs:label "ribosomal protein S6 kinase alpha" ; rdfs:comment "A protein that has a core domain composition consisting of a Protein kinase domain (Pfam:PF00069) followed by a Protein kinase C terminal domain (Pfam:PF00433) and another copy of the a Protein kinase domain (Pfam:PF00069). Prototype members of this class act downstream of ERK1/2 signaling pahtway. There are two functional kinase domains that are activated in a sequential manner by a series of phosphorylations." ; rdfs:subClassOf obo:PR_000000001 . obo:GO_0140115 a rdfs:Class ; rdfs:label "export across plasma membrane" ; rdfs:comment "The directed movement of some substance from inside of a cell, across the plasma membrane and into the extracellular region." ; rdfs:subClassOf obo:GO_0055085 , obo:GO_0140352 . a rdfs:Class ; rdfs:label "Deglutition Disorders [Disease/Finding]" ; rdfs:subClassOf , . obo:OGG_3043740571 a rdfs:Class ; rdfs:label "M gene of severe acute respiratory syndrome coronavirus 2" ; rdfs:subClassOf obo:OGG_2002697049 . a rdfs:Class ; rdfs:label "DASATINIB" ; rdfs:subClassOf . obo:CHEBI_38632 a rdfs:Class ; rdfs:label "membrane transport modulator" ; rdfs:comment "Any agent that affects the transport of molecular entities across a biological membrane." ; rdfs:subClassOf obo:CHEBI_52208 . obo:CIDO_0000537 a rdfs:Class ; rdfs:label "QPTEDVVDGDVVIRE" ; rdfs:comment "A coronavirus epitope that is part of some S protein from HCoV HKU1 composed of the following amino acids QPTEDVVDGDVVIRE" ; rdfs:subClassOf obo:CIDO_0000450 . obo:GO_0031325 a rdfs:Class ; rdfs:label "positive regulation of cellular metabolic process" ; rdfs:comment "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways by which individual cells transform chemical substances." ; rdfs:subClassOf obo:GO_0009893 , obo:GO_0031323 , obo:GO_0048522 . obo:CHEBI_138880 a rdfs:Class ; rdfs:label "autophagy inducer" ; rdfs:comment "Any compound that induces the process of autophagy (the self-digestion of one or more components of a cell through the action of enzymes originating within the same cell)." ; rdfs:subClassOf obo:CHEBI_52206 . obo:NCBITaxon_1503288 a rdfs:Class ; rdfs:label "BtMf-AlphaCoV/JX2012" ; rdfs:subClassOf obo:NCBITaxon_694000 . obo:PR_000050263 a rdfs:Class ; rdfs:label "rep gene translation product (SARS-CoV-2)" ; rdfs:comment "A protein that is a translation product of the rep gene in SARS-CoV-2." ; rdfs:subClassOf obo:PR_000050262 . obo:NCBITaxon_864599 a rdfs:Class ; rdfs:label "Bat coronavirus BM48-35/BGR/2008" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:CIDO_0000576 a rdfs:Class ; rdfs:label "VETYIKWPWWVWLCI" ; rdfs:comment "A coronavirus epitope that is part of some S protein from HCoV 229E composed of the following amino acids VETYIKWPWWVWLCI" ; rdfs:subClassOf obo:CIDO_0000451 . obo:CHEBI_59874 a rdfs:Class ; rdfs:label "N-acyl-L-alpha-amino acid anion" ; rdfs:comment "A carboxylic acid anion that is the conjugate base of an N-acyl-L-alpha-amino acid arising from deprotonation of the C-1 carboxy group." ; rdfs:subClassOf obo:CHEBI_29067 . obo:NCBITaxon_314147 a rdfs:Class ; rdfs:label "Glires" ; rdfs:subClassOf obo:NCBITaxon_314146 . obo:NCBITaxon_249082 a rdfs:Class ; rdfs:label "SARS coronavirus ZS-A" ; rdfs:subClassOf obo:NCBITaxon_694009 . obo:PR_Q9H3K2 a rdfs:Class ; rdfs:label "growth hormone-inducible transmembrane protein (human)" ; rdfs:comment "A growth hormone-inducible transmembrane protein that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000029067 , obo:PR_000031521 . obo:PR_000029127 a rdfs:Class ; rdfs:label "myosin light chain kinase family member 4" ; rdfs:comment "A protein that is a translation product of the human MYLK4 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:PR_000012208 a rdfs:Class ; rdfs:label "polyadenylate-binding protein 4" ; rdfs:comment "A protein that is a translation product of the human PABPC4 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:PR_000029377 a rdfs:Class ; rdfs:label "DDB1- and CUL4-associated factor 7" ; rdfs:comment "A protein that is a translation product of the human DCAF7 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . a rdfs:Class ; rdfs:label "LOPINAVIR" ; rdfs:subClassOf . obo:OAE_0000022 a rdfs:Class ; rdfs:label "pain in extremity AE" ; rdfs:comment "a pain AE where the pain reachs an extreme level." ; rdfs:subClassOf obo:OAE_0000374 . obo:CIDO_0000976 a rdfs:Class ; rdfs:label "SARS-CoV2 orf3a protein binding to human SUN2" ; rdfs:comment "SARS-CoV2 orf3a protein binding to human SUN2, as evidented by an affinity-purification mass spectrometry experiment" ; rdfs:subClassOf obo:CIDO_0000584 . obo:CHEBI_46629 a rdfs:Class ; rdfs:label "oxo group" ; rdfs:subClassOf obo:CHEBI_33246 . obo:CIDO_0000194 a rdfs:Class ; rdfs:label "TMPRSS2 cutting open S protein of SARS-CoV-2"@en ; rdfs:comment "A SARS-CoV-2 viral process in which after a SARS-CoV-2 virion attaches to a target cell, the cell's protease TMPRSS2 cuts open the spike protein of the virus, exposing a fusion peptide in the S2 subunit, and the host receptor ACE2." ; rdfs:subClassOf obo:CIDO_0000197 . obo:CHEBI_58954 a rdfs:Class ; rdfs:label "straight-chain saturated fatty acid anion" ; rdfs:comment "Any saturated fatty acid anion lacking a carbon side-chain." ; rdfs:subClassOf obo:CHEBI_58953 . obo:PR_000012706 a rdfs:Class ; rdfs:label "GPI transamidase component PIG-S" ; rdfs:comment "A protein that is a translation product of the human PIGS gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:NCBITaxon_249075 a rdfs:Class ; rdfs:label "SARS coronavirus HZS2-E" ; rdfs:subClassOf obo:NCBITaxon_694009 . obo:CHEBI_135947 a rdfs:Class ; rdfs:label "bazedoxifene" ; rdfs:subClassOf obo:CHEBI_48559 . obo:CIDO_0000457 a rdfs:Class ; rdfs:label "CLIA certified laboratory"@en ; rdfs:comment "A laboratory is certified by the Center for Medicare and Medicaid Services (CMS) accoring to the criteria listed in 42CFR 493.17 based on the Clinical Laboratory Improvement Amendments (CLIA) regulattion." ; rdfs:subClassOf obo:OBI_0000245 . obo:CHEBI_24869 a rdfs:Class ; rdfs:label "ionophore" ; rdfs:comment "A compound which can carry specific ions through membranes of cells or organelles." ; rdfs:subClassOf obo:CHEBI_38632 . obo:PR_000001465 a rdfs:Class ; rdfs:label "high affinity immunoglobulin gamma Fc receptor I" ; rdfs:comment "An immunoglobulin gamma Fc receptor I that is a translation product of the human FCGR1A gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000001356 . a rdfs:Class ; rdfs:label "Hydrocarbons, Halogenated [Chemical/Ingredient]" ; rdfs:subClassOf . obo:CIDO_0000857 a rdfs:Class ; rdfs:label "SARS-CoV2 nsp13 protein binding to human TBK1" ; rdfs:comment "SARS-CoV2 nsp13 protein binding to human TBK1, as evidented by an affinity-purification mass spectrometry experiment" ; rdfs:subClassOf obo:CIDO_0000058 . obo:CHEBI_78116 a rdfs:Class ; rdfs:label "fatty acid anion 6:0" ; rdfs:comment "Any saturated fatty acid anion containing 6 carbons. Formed by deprotonation of the carboxylic acid moiety. Major species at pH 7.3." ; rdfs:subClassOf obo:CHEBI_58953 , obo:CHEBI_59558 . obo:NCBITaxon_2569586 a rdfs:Class ; rdfs:label "Canada goose coronavirus" ; rdfs:subClassOf obo:NCBITaxon_1433214 . obo:CHEBI_25105 a rdfs:Class ; rdfs:label "macrolide antibiotic" ; rdfs:comment "A macrocyclic lactone with a ring of twelve or more members which exhibits antibiotic activity." ; rdfs:subClassOf obo:CHEBI_25106 . obo:NCBITaxon_566558 a rdfs:Class ; rdfs:label "Bat coronavirus Trinidad/1FY2BA/2007" ; rdfs:subClassOf obo:NCBITaxon_366617 . obo:GO_0046854 a rdfs:Class ; rdfs:label "phosphatidylinositol phosphate biosynthetic process" ; rdfs:comment "The chemical reactions and pathways resulting in the formation of phosphatidylinositol phosphate." ; rdfs:subClassOf obo:GO_0006661 . a rdfs:Class ; rdfs:label "FLUPHENAZINE" ; rdfs:subClassOf . a rdfs:Class ; rdfs:label "HIV Protease Inhibitors [MoA]" ; rdfs:subClassOf . obo:OBI_0000971 a rdfs:Class ; rdfs:label "fresh specimen" ; rdfs:comment "a specimen that is output of a specimen creation process used for an investigation without storage." ; rdfs:subClassOf obo:OBI_0001472 . obo:PR_Q08334 a rdfs:Class ; rdfs:label "interleukin-10 receptor subunit beta (human)" ; rdfs:comment "An interleukin-10 receptor subunit beta that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000008979 , obo:PR_000029067 . obo:CHEBI_64677 a rdfs:Class ; rdfs:label "daunorubicin(1+)" ; rdfs:comment "An anthracycline cation that is the conjugate acid of daunorubicin, arising from protonation of the amino group." ; rdfs:subClassOf obo:CHEBI_64678 . obo:ENVO_00010358 a rdfs:Class ; rdfs:label "fomite" ; rdfs:comment "A fomite is any inanimate object or substance capable of carrying infectious organisms (such as germs or parasites) and hence transferring them from one individual to another. A fomite can be anything such as a cloth or mop heads so when cleaning this is important to remember that this could aid when spreading pathogenic organisms." ; rdfs:subClassOf obo:BFO_0000030 . obo:NCBITaxon_443240 a rdfs:Class ; rdfs:label "Human coronavirus HKU1 (isolate N2)" ; rdfs:subClassOf obo:NCBITaxon_290028 . a rdfs:Class ; rdfs:label "Hepatitis, Autoimmune [Disease/Finding]" ; rdfs:subClassOf , . obo:CIDO_0020278 a rdfs:Class ; rdfs:label "SARS-CoV-2 Real-Time RT-PCR-Test" ; rdfs:seeAlso ; rdfs:subClassOf obo:CIDO_0000454 . obo:PR_000005341 a rdfs:Class ; rdfs:label "centrosomal protein of 135 kDa" ; rdfs:comment "A protein that is a translation product of the human CEP135 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:PR_000001613 a rdfs:Class ; rdfs:label "muscarinic acetylcholine receptor M1" ; rdfs:comment "A muscarinic acetylcholine receptor that is a translation product of the human CHRM1 gene or a 1:1 ortholog thereof. This receptor mediates slow excitatory postsynaptic potential in the postganglionic nerve and is also expressed in exocrine glands and in the central nervous system." ; rdfs:subClassOf obo:PR_000001488 . a rdfs:Class ; rdfs:label "Methylprednisolone [Chemical/Ingredient]" ; rdfs:subClassOf . obo:CHEBI_76932 a rdfs:Class ; rdfs:label "pathway inhibitor" ; rdfs:comment "An enzyme inhibitor that interferes with one or more steps in a metabolic pathway." ; rdfs:subClassOf obo:CHEBI_23924 . a rdfs:Class ; rdfs:label "Embolism and Thrombosis [Disease/Finding]" ; rdfs:subClassOf . obo:PR_000016377 a rdfs:Class ; rdfs:label "serine/threonine-protein kinase tousled-like 1" ; rdfs:comment "A protein that is a translation product of the human TLK1 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:PR_000010203 a rdfs:Class ; rdfs:label "methionine adenosyltransferase 2 subunit beta" ; rdfs:comment "A protein that is a translation product of the human MAT2B gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:GO_0014068 a rdfs:Class ; rdfs:label "positive regulation of phosphatidylinositol 3-kinase signaling" ; rdfs:comment "Any process that activates or increases the frequency, rate or extent of signal transduction mediated by the phosphatidylinositol 3-kinase cascade." ; rdfs:subClassOf obo:GO_0014066 , obo:GO_1902533 . obo:VO_0000590 a rdfs:Class ; rdfs:label "vaccine preparation" ; rdfs:comment "vaccine preparation is a manufacturing process to produce a vaccine." ; rdfs:subClassOf obo:OBI_0000011 . obo:CHEBI_33287 a rdfs:Class ; rdfs:label "fertilizer" ; rdfs:comment "A fertilizer is any substance that is added to soil or water to assist the growth of plants." ; rdfs:subClassOf obo:CHEBI_33286 . obo:UBERON_0000947 a rdfs:Class ; rdfs:label "aorta" ; rdfs:comment "The main trunk of the systemic arterial system that carries blood from the heart to all the organs and other structures of the body, bringing oxygenated blood to all parts of the body in the systemic circulation" ; rdfs:subClassOf obo:UBERON_0000465 . obo:CHEBI_32451 a rdfs:Class ; rdfs:label "D-cysteinium" ; rdfs:comment "The D-enantiomer of cysteinium." ; rdfs:subClassOf obo:CHEBI_32458 . obo:NCBITaxon_727989 a rdfs:Class ; rdfs:label "Ferret systemic coronavirus MSU-S" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:NCBITaxon_931916 a rdfs:Class ; rdfs:label "Alphacoronavirus Eptesicus fuscus/Appalachian Ridge/P1-C146/IT/USA/2009" ; rdfs:subClassOf obo:NCBITaxon_366617 . obo:CHEBI_33535 a rdfs:Class ; rdfs:label "sulfur hydride" ; rdfs:subClassOf obo:CHEBI_26835 , obo:CHEBI_36902 . obo:PR_P22413 a rdfs:Class ; rdfs:label "ectonucleotide pyrophosphatase/phosphodiesterase family member 1 (human)" ; rdfs:comment "An ectonucleotide pyrophosphatase/phosphodiesterase family member 1 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000007087 , obo:PR_000029067 . obo:CHEBI_94807 a rdfs:Class ; rdfs:label "acetic acid [2-[[(5-nitro-2-thiazolyl)amino]-oxomethyl]phenyl] ester" ; rdfs:subClassOf obo:CHEBI_22702 , obo:CHEBI_33308 . obo:CIDO_0000950 a rdfs:Class ; rdfs:label "SARS-CoV2 nsp9 protein binding to human FBN1" ; rdfs:comment "SARS-CoV2 nsp9 protein binding to human FBN1, as evidented by an affinity-purification mass spectrometry experiment" ; rdfs:subClassOf obo:CIDO_0000583 . obo:PR_000050282 a rdfs:Class ; rdfs:label "ORF1a proteolytic cleavage product (SARS-CoV-2)" ; rdfs:comment "A replicase polyprotein 1a (SARS-CoV-2) that has been processed by proteolytic cleavage." ; rdfs:subClassOf obo:PR_P0DTC1-1 . obo:CHEBI_141668 a rdfs:Class ; rdfs:label "L-tyrosinal(1+)" ; rdfs:comment "A primary ammonium ion resulting from the protonation of the amino group of L-tyrosinal." ; rdfs:subClassOf obo:CHEBI_65296 . a rdfs:Class ; rdfs:label "Progesterone [Chemical/Ingredient]" ; rdfs:subClassOf , , . obo:NCBITaxon_702700 a rdfs:Class ; rdfs:label "Bovine coronavirus Bubalus/339/ITA/2007" ; rdfs:subClassOf obo:NCBITaxon_11128 . obo:CIDO_0000038 a rdfs:Class ; rdfs:label "COVID-19 diagnostic process using nucleic acid detection"@en ; rdfs:comment "A COVID-19 diagnostic process that detects SARS-CoV-2 by amplification and identification of nucleic acids of SARS-CoV-2." ; rdfs:subClassOf obo:CIDO_0000424 . a rdfs:Class ; rdfs:label "Hepatitis [Disease/Finding]" ; rdfs:subClassOf . obo:PR_000005417 a rdfs:Class ; rdfs:label "serine/threonine-protein kinase Chk1" ; rdfs:comment "A protein that is a translation product of the human CHEK1 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:VO_0005111 a rdfs:Class ; rdfs:label "MERS-CoV S vaccine adjuvanted with CpG and Alum" ; rdfs:comment "A MERS subunit vaccine that has a combined adjuvant of aluminum hydroxide and CpG oligodeoxynucleotides." ; rdfs:subClassOf obo:VO_0004900 . a rdfs:Class ; rdfs:label "Hematologic Diseases [Disease/Finding]" ; rdfs:subClassOf . obo:CIDO_0000879 a rdfs:Class ; rdfs:label "SARS-CoV2 nsp4 protein binding to human NUP210" ; rdfs:comment "SARS-CoV2 nsp4 protein binding to human NUP210, as evidented by an affinity-purification mass spectrometry experiment" ; rdfs:subClassOf obo:CIDO_0000581 . obo:PR_000004712 a rdfs:Class ; rdfs:label "breakpoint cluster region protein" ; rdfs:comment "A protein that is a translation product of the human BCR gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:OBI_0002554 a rdfs:Class ; rdfs:label "vagina specimen" ; rdfs:comment "A specimen that is derived from vagina." ; rdfs:subClassOf obo:OBI_0001479 . a rdfs:Class ; rdfs:label "EVEROLIMUS" ; rdfs:subClassOf . obo:PR_P36897 a rdfs:Class ; rdfs:label "TGF-beta receptor type-1 (human)" ; rdfs:comment "A TGF-beta receptor type-1 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000000047 , obo:PR_000029067 . obo:CIDO_0000919 a rdfs:Class ; rdfs:label "SARS-CoV2 nsp7 protein binding to human SCARB1" ; rdfs:comment "SARS-CoV2 nsp7 protein binding to human SCARB1, as evidented by an affinity-purification mass spectrometry experiment" ; rdfs:subClassOf obo:CIDO_0000049 . obo:VO_0005185 a rdfs:Class ; rdfs:label "mRNA-1283"@en ; rdfs:comment "A SARS-CoV-2 refrigerator-stable mRNA vaccine by Moderna that encodes for the portions of the SARS-CoV-2 spike protein critical for neutralization, specifically the Receptor Binding Domain (RBD) and N-terminal Domain (NTD)" ; rdfs:subClassOf obo:VO_0005198 . obo:CHEBI_36044 a rdfs:Class ; rdfs:label "antiviral drug" ; rdfs:comment "A substance used in the prophylaxis or therapy of virus diseases." ; rdfs:subClassOf obo:CHEBI_22587 , obo:CHEBI_36043 . obo:CHEBI_131489 a rdfs:Class ; rdfs:label "N-[2-(4-bromocinnamylamino)ethyl]isoquinoline-5-sulfonamide(2+)" ; rdfs:comment "An organic cation obtained by protonation of the isoquinoline and secondary amino functions of N-[2-(4-bromocinnamylamino)ethyl]isoquinoline-5-sulfonamide." ; rdfs:subClassOf obo:CHEBI_25697 , obo:CHEBI_35274 . a rdfs:Class ; rdfs:label "Hemic/Lymphatic Activity Alteration [PE]" ; rdfs:subClassOf . obo:VO_0005097 a rdfs:Class ; rdfs:label "Soberana 02" ; rdfs:comment "A SARS-CoV-2 subunit vaccine developed by Finlay Vaccine Institute (IFV)" ; rdfs:subClassOf obo:VO_0005202 , obo:VO_0005269 . obo:CHEBI_35342 a rdfs:Class ; rdfs:label "17alpha-hydroxy steroid" ; rdfs:comment "The alpha-stereoisomer of 17-hydroxy steroid." ; rdfs:subClassOf obo:CHEBI_36838 . obo:NCBITaxon_591069 a rdfs:Class ; rdfs:label "Murine coronavirus RA59/R13" ; rdfs:subClassOf obo:NCBITaxon_11138 . obo:NCBITaxon_230237 a rdfs:Class ; rdfs:label "Porcine hemagglutinating encephalomyelitis virus (strain 67N)" ; rdfs:subClassOf obo:NCBITaxon_42005 . obo:HP_0004469 a rdfs:Class ; rdfs:label "Chronic bronchitis" ; rdfs:comment "Chronic inflammation of the bronchi." ; rdfs:subClassOf obo:HP_0011947 . obo:GO_0050715 a rdfs:Class ; rdfs:subClassOf obo:CIDO_0000409 . obo:PR_000010127 a rdfs:Class ; rdfs:label "dual specificity mitogen-activated protein kinase kinase 5" ; rdfs:comment "A protein that is a translation product of the human MAP2K5 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:PR_000002005 a rdfs:Class ; rdfs:label "G protein-activated inward rectifier potassium channel 4" ; rdfs:comment "A G protein-activated inward rectifier potassium channel that is a translation product of the human KCNJ5 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000001814 . obo:DRON_00023181 a rdfs:Class ; rdfs:label "Promethazine Oral Tablet" ; rdfs:subClassOf obo:DRON_00000022 . obo:NCBITaxon_338605 a rdfs:Class ; rdfs:label "Bat SARS coronavirus HKU3-2" ; rdfs:subClassOf obo:NCBITaxon_442736 . obo:CIDO_0020230 a rdfs:Class ; rdfs:label "Panther Fusion SARS-CoV-2 assay" ; rdfs:seeAlso ; rdfs:subClassOf obo:CIDO_0000454 . obo:NCBITaxon_305403 a rdfs:Class ; rdfs:label "SARS coronavirus A021" ; rdfs:subClassOf obo:NCBITaxon_694009 . obo:NCBITaxon_1306931 a rdfs:Class ; rdfs:label "Human betacoronavirus 2c Jordan-N3/2012" ; rdfs:subClassOf obo:NCBITaxon_1335626 . obo:APOLLO_SV_00000581 a rdfs:Class ; rdfs:label "infectious disease forecast objective specification"@en ; rdfs:comment "An objective specification that is realized by the estimation of one or more predicted data items that are about 1) some infection in ecosystem and 2) potential changes to its number of participants (e.g., individuals within a host population, individuals within a vector population) relative to a particular temporal region; and is part of some infectious disease forecasting software."@en ; rdfs:subClassOf obo:IAO_0000005 . obo:PR_000013895 a rdfs:Class ; rdfs:label "proto-oncogene tyrosine-protein kinase receptor Ret" ; rdfs:comment "A protein that is a translation product of the human RET gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:CIDO_0001147 a rdfs:Class ; rdfs:label "SARS-CoV-2 pp1a protein amino acid deletion"@en ; rdfs:subClassOf obo:CIDO_0001149 . obo:GO_0043278 a rdfs:Class ; rdfs:label "response to morphine" ; rdfs:comment "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a morphine stimulus. Morphine is an opioid alkaloid, isolated from opium, with a complex ring structure." ; rdfs:subClassOf obo:GO_0014072 . obo:CHEBI_35717 a rdfs:Class ; rdfs:label "sedative" ; rdfs:comment "A central nervous system depressant used to induce drowsiness or sleep or to reduce psychological excitement or anxiety." ; rdfs:subClassOf obo:CHEBI_35488 . obo:CHEBI_18186 a rdfs:Class ; rdfs:label "tyrosine" ; rdfs:comment "An alpha-amino acid that is phenylalanine bearing a hydroxy substituent at position 4 on the phenyl ring." ; rdfs:subClassOf obo:CHEBI_26167 , obo:CHEBI_33704 , obo:CHEBI_33856 . obo:CHEBI_39173 a rdfs:Class ; rdfs:label "chloropyridine" ; rdfs:comment "Compounds containing a pyridine nucleus substituted with one or more chlorine atoms." ; rdfs:subClassOf obo:CHEBI_26421 , obo:CHEBI_36683 . obo:PR_O14976 a rdfs:Class ; rdfs:label "cyclin-G-associated kinase (human)" ; rdfs:comment "A cyclin-G-associated kinase that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000007805 , obo:PR_000029067 . obo:HP_0031249 a rdfs:Class ; rdfs:label "Parageusia" ; rdfs:comment "A distortion of the sense of taste, often characterized by the sensation of a metallic taste." ; rdfs:subClassOf obo:HP_0000223 . obo:CHEBI_6618 a rdfs:Class ; rdfs:label "Met-enkephalin" ; rdfs:comment "A pentapeptide comprising L-tyrosine, glycine, glycine, L-phenylalanine and L-methionine residues joined in sequence by peptide linkages. It is an endogenous opioid peptide with antitumor, analgesic, and immune-boosting properties." ; rdfs:subClassOf obo:CHEBI_48545 . obo:CHEBI_170008 a rdfs:Class ; rdfs:label "azabicyclohexane" ; rdfs:subClassOf obo:CHEBI_27171 . obo:PR_P62913 a rdfs:Class ; rdfs:label "60S ribosomal protein L11 (human)" ; rdfs:comment "A 60S ribosomal protein L11 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000014190 , obo:PR_000029067 . obo:PR_000050276 a rdfs:Class ; rdfs:label "non-structural protein 7 (SARS-CoV-2)" ; rdfs:comment "A rep gene proteolytic cleavage product (SARS-CoV-2) that is the central portion produced by the enzymatic action of 3CL-PRO proteinase (nsp5) when it cleaves the precursor rep gene translation product (SARS-CoV-2) between residues 3859-3860 and 3942-3943." ; rdfs:subClassOf obo:PR_000050281 . obo:OBI_0600052 a rdfs:Class ; rdfs:label "dialysis"@en ; rdfs:comment "a protocol application that uses diffusion through a semi-permeable membrane to separate an input material into two fractions of different composition"@en ; rdfs:subClassOf obo:OBI_0600014 . obo:CHEBI_36962 a rdfs:Class ; rdfs:label "organochalcogen compound" ; rdfs:comment "An organochalcogen compound is a compound containing at least one carbon-chalcogen bond." ; rdfs:subClassOf obo:CHEBI_33285 , obo:CHEBI_33304 . obo:CIDO_0000807 a rdfs:Class ; rdfs:label "SARS-CoV2 nsp12 protein binding to human MYCBP2" ; rdfs:comment "SARS-CoV2 nsp12 protein binding to human MYCBP2, as evidented by an affinity-purification mass spectrometry experiment" ; rdfs:subClassOf obo:CIDO_0000057 . obo:NCBITaxon_2749450 a rdfs:Class ; rdfs:label "Coronavirus cyc-BetaCoV/2019" ; rdfs:subClassOf obo:NCBITaxon_1986197 . obo:PR_Q96MM7 a rdfs:Class ; rdfs:label "heparan-sulfate 6-O-sulfotransferase 2 (human)" ; rdfs:comment "A heparan-sulfate 6-O-sulfotransferase 2 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000008766 , obo:PR_000029067 . obo:CHEBI_149564 a rdfs:Class ; rdfs:label "hydroxychloroquine(2+)" ; rdfs:comment "A quinolinium ion obtained by protonation of the quinoline nitrogen and tertiary amino group of the antimalarial drug hydroxychloroquine. It is the major species at pH 7.3." ; rdfs:subClassOf obo:CHEBI_137982 , obo:CHEBI_52837 . obo:GO_0051240 a rdfs:Class ; rdfs:label "positive regulation of multicellular organismal process" ; rdfs:comment "Any process that activates or increases the frequency, rate or extent of an organismal process, any of the processes pertinent to the function of an organism above the cellular level; includes the integrated processes of tissues and organs." ; rdfs:subClassOf obo:GO_0048518 , obo:GO_0051239 . obo:CIDO_0020058 a rdfs:Class ; rdfs:label "Biohit SARS-CoV-2 IgM/IgG Antibody Test Kit" ; rdfs:seeAlso ; rdfs:subClassOf obo:CIDO_0000454 . a rdfs:Class ; rdfs:label "Urologic Diseases [Disease/Finding]" ; rdfs:subClassOf , . obo:NCBITaxon_389154 a rdfs:Class ; rdfs:label "Bat coronavirus (BtCoV/A900/2005)" ; rdfs:subClassOf obo:NCBITaxon_389126 . obo:PR_000008768 a rdfs:Class ; rdfs:label "heat shock factor-binding protein 1" ; rdfs:comment "A protein that is a translation product of the human HSBP1 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:CHEBI_48888 a rdfs:Class ; rdfs:label "pyridoindole" ; rdfs:subClassOf obo:CHEBI_26979 , obo:CHEBI_38101 . obo:CHEBI_51270 a rdfs:Class ; rdfs:label "tetracenes" ; rdfs:comment "Compounds containing a tetracene skeleton." ; rdfs:subClassOf obo:CHEBI_51269 . a rdfs:Class ; rdfs:label "Blood Protein Disorders [Disease/Finding]" ; rdfs:subClassOf . obo:NCBITaxon_694001 a rdfs:Class ; rdfs:label "Miniopterus bat coronavirus HKU8" ; rdfs:subClassOf obo:NCBITaxon_2509497 . obo:PR_000002307 a rdfs:Class ; rdfs:label "apoptosis regulator Bcl-2" ; rdfs:comment "A Bcl-2-like apoptosis inhibitor that is a translation product of the human BCL2 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000002186 . a rdfs:Class ; rdfs:label "Neurodegenerative Diseases [Disease/Finding]" ; rdfs:subClassOf . obo:DRON_00001134 a rdfs:Class ; rdfs:label "Chloroquine solution"@en ; rdfs:subClassOf obo:DRON_00000020 . obo:NCBITaxon_389146 a rdfs:Class ; rdfs:label "Bat coronavirus (BtCoV/A819/2005)" ; rdfs:subClassOf obo:NCBITaxon_389126 . obo:OPMI_0000564 a rdfs:Class ; rdfs:label "drug exposure temporal region"@en ; rdfs:comment "the date or time on which a drug exposure occurs in a patient" ; rdfs:subClassOf obo:BFO_0000148 . obo:NCBITaxon_2042546 a rdfs:Class ; rdfs:label "Coronavirus PREDICT CoV-2" ; rdfs:subClassOf obo:NCBITaxon_696098 . obo:CHEBI_180482 a rdfs:Class ; rdfs:label "1,2,4-triazole-3-carboxamide" ; rdfs:comment "A member of the class of triazoles that is 1H-1,2,4-triazole substituted by an aminocarbonyl group at position 3. It is the major catabolite and aglycon of ribavirin." ; rdfs:subClassOf obo:CHEBI_140324 , obo:CHEBI_29347 , obo:CHEBI_35727 , obo:CHEBI_62733 . obo:PR_000010173 a rdfs:Class ; rdfs:label "microtubule-associated protein tau" ; rdfs:comment "A protein that is a translation product of the human MAPT gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:NCBITaxon_8578 a rdfs:Class ; rdfs:label "Colubridae" ; rdfs:subClassOf obo:NCBITaxon_34989 . a rdfs:Class ; rdfs:label "Central Nervous System Depression [PE]" ; rdfs:subClassOf . obo:CHEBI_33836 a rdfs:Class ; rdfs:label "benzenoid aromatic compound" ; rdfs:subClassOf obo:CHEBI_33598 , obo:CHEBI_33659 . obo:PR_000010136 a rdfs:Class ; rdfs:label "mitogen-activated protein kinase kinase kinase 3" ; rdfs:comment "A protein that is a translation product of the human MAP3K3 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:PR_000008056 a rdfs:Class ; rdfs:label "glutamate dehydrogenase 1, mitochondrial" ; rdfs:comment "A protein that is a translation product of the human GLUD1 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:CHEBI_25555 a rdfs:Class ; rdfs:label "nitrogen atom" ; rdfs:subClassOf obo:CHEBI_25585 , obo:CHEBI_33300 . obo:CHEBI_33672 a rdfs:Class ; rdfs:label "heterobicyclic compound" ; rdfs:comment "A bicyclic compound in which at least one of the rings contains at least one skeletal heteroatom." ; rdfs:subClassOf obo:CHEBI_33636 , obo:CHEBI_5686 . obo:OBI_1110022 a rdfs:Class ; rdfs:label "adaptive immune receptor"@en ; rdfs:comment "is a receptor produced by cells of the adaptive immune system with the purpose of binding epitopes."@en ; rdfs:subClassOf obo:GO_0032991 . a rdfs:Class ; rdfs:label "Chloride Channel Interactions [MoA]" ; rdfs:subClassOf . obo:CIDO_0000663 a rdfs:Class ; rdfs:label "D796Y in SARS-CoV-2 S protein" ; rdfs:comment "An AA mutation or AA variant that has mutated an amino acid at position 796 into a tyrosine in S protein." ; rdfs:subClassOf obo:CIDO_0001158 . obo:PR_P26358 a rdfs:Class ; rdfs:label "DNA (cytosine-5)-methyltransferase 1 (human)" ; rdfs:comment "A DNA (cytosine-5)-methyltransferase 1 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000006606 , obo:PR_000029067 . obo:PR_000010367 a rdfs:Class ; rdfs:label "lactadherin" ; rdfs:comment "A protein that is a translation product of the human MFGE8 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:CHEBI_189651 a rdfs:Class ; rdfs:label "dBET6" ; rdfs:subClassOf obo:CHEBI_50860 . obo:VO_0005253 a rdfs:Class ; rdfs:label "Koçak-19 Inaktif Adjuvanlı COVID-19 Vaccine"@en ; rdfs:comment "A SARS-CoV-2 inactivated virus vaccine by Kocak Farma" ; rdfs:subClassOf obo:VO_0005201 . obo:NCBITaxon_231426 a rdfs:Class ; rdfs:label "Avian infectious bronchitis virus (strain SAIB20)" ; rdfs:subClassOf obo:NCBITaxon_11120 . obo:CIDO_0020051 a rdfs:Class ; rdfs:label "BioCode SARS-CoV-2 Assay" ; rdfs:seeAlso ; rdfs:subClassOf obo:CIDO_0000454 . obo:PR_Q96HR9 a rdfs:Class ; rdfs:label "receptor expression-enhancing protein 6 (human)" ; rdfs:comment "A receptor expression-enhancing protein 6 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000013868 , obo:PR_000029067 . obo:PR_000001166 a rdfs:Class ; rdfs:label "5-hydroxytryptamine receptor 2A" ; rdfs:comment "A 5-hydroxytryptamine receptor 2 that is a translation product of the human HTR2A gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000001099 . obo:PR_P82675 a rdfs:Class ; rdfs:label "28S ribosomal protein S5, mitochondrial (human)" ; rdfs:comment "A 28S ribosomal protein S5, mitochondrial that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000010643 , obo:PR_000029067 . obo:CHEBI_50471 a rdfs:Class ; rdfs:label "primary arylamine" ; rdfs:comment "A primary amine formally derived from ammonia by replacing one hydrogen atom by an aryl group. R-NH2 where R is an aryl group." ; rdfs:subClassOf obo:CHEBI_32877 , obo:CHEBI_33860 . obo:PR_000003583 a rdfs:Class ; rdfs:label "tyrosine-protein kinase ABL2" ; rdfs:comment "A protein that is a translation product of the human ABL2 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:CHEBI_22563 a rdfs:Class ; rdfs:label "anion" ; rdfs:comment "A monoatomic or polyatomic species having one or more elementary charges of the electron." ; rdfs:subClassOf obo:CHEBI_24870 . obo:PR_Q96CN9 a rdfs:Class ; rdfs:label "GRIP and coiled-coil domain-containing protein 1 (human)" ; rdfs:comment "A GRIP and coiled-coil domain-containing protein 1 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000007886 , obo:PR_000029067 . obo:CIDO_0000356 a rdfs:Class ; rdfs:label "vasoconstrictor role"@en ; rdfs:comment "A role taken by a chemical entity (including a drug or natural entity) that causes the contraction of the muscular wall of the vessels, in particular the large arteries and small arterioles, leadin to the narrowing of the blood vessels" ; rdfs:subClassOf obo:BFO_0000023 . obo:GO_0046907 a rdfs:Class ; rdfs:label "intracellular transport" ; rdfs:comment "The directed movement of substances within a cell." ; rdfs:subClassOf obo:GO_0006810 , obo:GO_0051234 , obo:GO_0051641 . obo:VO_0005145 a rdfs:Class ; rdfs:label "MERS GLS-5300 vaccine" ; rdfs:comment "A MERS DNA Vaccine that is made of the plasmid pGX9109 expressing MERS S protein." ; rdfs:subClassOf obo:VO_0004900 . obo:PR_P46734 a rdfs:Class ; rdfs:label "dual specificity mitogen-activated protein kinase kinase 3 (human)" ; rdfs:comment "A dual specificity mitogen-activated protein kinase kinase 3 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000003284 , obo:PR_000029067 . obo:CHEBI_22750 a rdfs:Class ; rdfs:label "benzylisoquinoline alkaloid" ; rdfs:comment "Any isoquinoline alkaloid based on a benzylisoquinoline skeleton." ; rdfs:subClassOf obo:CHEBI_24921 . obo:PR_000001446 a rdfs:Class ; rdfs:label "discoidin domain-containing receptor 2" ; rdfs:comment "A discoidin domain-containing receptor that is a translation product of the human DDR2 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000001342 . obo:NCBITaxon_1739625 a rdfs:Class ; rdfs:label "SARS-like coronavirus WIV16" ; rdfs:subClassOf obo:NCBITaxon_2720068 . obo:NCBITaxon_2691590 a rdfs:Class ; rdfs:label "Pipistrellus abramus bat coronavirus HKU5-related" ; rdfs:subClassOf obo:NCBITaxon_2664183 . obo:CHEBI_26004 a rdfs:Class ; rdfs:label "phenylpropanoid" ; rdfs:comment "Any organic aromatic compound with a structure based on a phenylpropane skeleton. The class includes naturally occurring phenylpropanoid esters, flavonoids, anthocyanins, coumarins and many small phenolic molecules as well as their semi-synthetic and synthetic analogues. Phenylpropanoids are also precursors of lignin." ; rdfs:subClassOf obo:CHEBI_33659 . obo:NCBITaxon_248485 a rdfs:Class ; rdfs:label "SARS coronavirus AS" ; rdfs:subClassOf obo:NCBITaxon_694009 . obo:PR_P09211 a rdfs:Class ; rdfs:label "glutathione S-transferase P (human)" ; rdfs:comment "A glutathione S-transferase P that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000029067 , obo:PR_000029113 . obo:CIDO_0000135 a rdfs:Class ; rdfs:label "SARS-CoV-2 binding to host cell"@en ; rdfs:comment "A host-coronovirus interaction that involves in the SARS-CoV-2 virus binding to a host cell" ; rdfs:subClassOf obo:CIDO_0000134 , obo:CIDO_0000197 . obo:NCBITaxon_741336 a rdfs:Class ; rdfs:label "Ferret enteric coronavirus" ; rdfs:subClassOf obo:NCBITaxon_1264898 . obo:NCBITaxon_643399 a rdfs:Class ; rdfs:label "Coronavirus oystercatcher/p17/2006/GBR" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:VO_0005105 a rdfs:Class ; rdfs:label "SARS CTLA4-S DNA vaccine" ; rdfs:comment "A SARS DNA vaccine that is made from CTLA4HingeSARS800 DNA with SARS-CoV S protein" ; rdfs:subClassOf obo:VO_0012183 . a rdfs:Class ; rdfs:label "Ribavirin [Chemical/Ingredient]" ; rdfs:subClassOf . obo:PR_Q15056 a rdfs:Class ; rdfs:label "eukaryotic translation initiation factor 4H (human)" ; rdfs:comment "A eukaryotic translation initiation factor 4H that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000007001 , obo:PR_000029067 . obo:NCBITaxon_231522 a rdfs:Class ; rdfs:label "SARS coronavirus GZ50" ; rdfs:subClassOf obo:NCBITaxon_694009 . obo:PR_P0DMS8 a rdfs:Class ; rdfs:label "adenosine receptor A3 (human)" ; rdfs:comment "An adenosine receptor A3 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000001578 , obo:PR_000029067 . obo:PR_000001565 a rdfs:Class ; rdfs:label "H4 histamine receptor" ; rdfs:comment "A histamine receptor that is a translation product of the human HRH4 gene or a 1:1 ortholog thereof. The preferred ligand is histamine. This receptor is expressed primarily in the bone marrow and eosinophils but also in a wide variety of peripheral tissues, including the heart, kidney, liver, lung, pancreas, skeletal muscle, prostate, small intestine, spleen, testis, colon, fetal liver and lymph node." ; rdfs:subClassOf obo:PR_000049994 . obo:CHEBI_83970 a rdfs:Class ; rdfs:label "cardiac glycoside" ; rdfs:comment "Steroid lactones containing sugar residues that act on the contractile force of the cardiac muscles." ; rdfs:subClassOf obo:CHEBI_24400 , obo:CHEBI_26766 . obo:OBI_0000917 a rdfs:Class ; rdfs:label "nasal swab specimen" ; rdfs:comment """A specimen obtained using a cotton swab on a stick, passed up the nostril to obtain a sample of exudate and epithelial debris for microbiological or cellular examination.""" ; rdfs:subClassOf obo:OBI_0002599 . obo:OBI_0302885 a rdfs:Class ; rdfs:label "filtration"@en ; rdfs:comment "filtration is a process which separates components suspended in a fluid based on granularity properties relying on a filter device"@en ; rdfs:subClassOf obo:OBI_0600014 . obo:OAE_0000403 a rdfs:Class ; rdfs:label "hypertension AE" ; rdfs:comment "an abnormal blood pressure AE that has an outcome of sustained high blood pressure at a level that is likely to result in cardiovascular disease and/or other pathological states" ; rdfs:subClassOf obo:OAE_0000381 . obo:CIDO_0000756 a rdfs:Class ; rdfs:label "SARS-CoV2 M protein binding to human FAM8A1" ; rdfs:comment "SARS-CoV2 M protein binding to human FAM8A1, as evidented by an affinity-purification mass spectrometry experiment" ; rdfs:subClassOf obo:CIDO_0000055 . obo:CHEBI_82980 a rdfs:Class ; rdfs:label "(2R,4S)-terconazole" ; rdfs:comment "A 1-(4-{[2-(2,4-dichlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy}phenyl)-4-isopropylpiperazine in which positions 2 and 4 of the 1,3-dioxolane moiety have R and S configuration, respectively." ; rdfs:subClassOf obo:CHEBI_82979 . obo:UBERON_0002168 a rdfs:Class ; rdfs:label "left lung" ; rdfs:comment "Lung which consists of the left upper lobe and left lower lobe.[FMA]" ; rdfs:subClassOf obo:UBERON_0002048 . obo:PR_000007956 a rdfs:Class ; rdfs:label "vitamin K-dependent gamma-carboxylase" ; rdfs:comment "A protein that is a translation product of the human GGCX gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:HP_0031676 a rdfs:Class ; rdfs:label "Monomorphic ventricular tachycardia" ; rdfs:comment "A type of ventricular tachycardia that is characterized by uniform QRS complexes within each lead (i.e., each QRS is identical or nearly so)." ; rdfs:subClassOf obo:HP_0004756 . obo:NCBITaxon_235088 a rdfs:Class ; rdfs:label "SARS coronavirus HSR 1" ; rdfs:subClassOf obo:NCBITaxon_694009 . obo:PR_Q9GZU3 a rdfs:Class ; rdfs:label "transmembrane protein 39B (human)" ; rdfs:comment "A transmembrane protein 39B that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000029067 , obo:PR_000031382 . a rdfs:Class ; rdfs:label "CLOMIPRAMINE" ; rdfs:subClassOf . obo:CIDO_0020245 a rdfs:Class ; rdfs:label "QiaStat-Dx Respiratory SARS-CoV-2 Panel" ; rdfs:seeAlso ; rdfs:subClassOf obo:CIDO_0000454 . obo:CIDO_0000277 a rdfs:Class ; rdfs:label "S-N501Y"@en ; rdfs:subClassOf obo:CIDO_0001157 . obo:VO_0005336 a rdfs:Class ; rdfs:label "AAV5-RBD-S"@en ; rdfs:comment "A SARS-CoV-2 recombinant viral vector vaccine by Biocad" ; rdfs:subClassOf obo:VO_0005199 . obo:CIDO_0000797 a rdfs:Class ; rdfs:label "SARS-CoV2 nsp10 protein binding to human AP2A2" ; rdfs:comment "SARS-CoV2 nsp10 protein binding to human AP2A2, as evidented by an affinity-purification mass spectrometry experiment" ; rdfs:subClassOf obo:CIDO_0000064 . obo:CHEBI_167095 a rdfs:Class ; rdfs:label "secondary fatty alcohol" ; rdfs:comment "A fatty alcohol consisting of a chain of 3 to greater than 27 carbon atoms in which a hydroxy group is attached to a saturated carbon atom different from the terminal carbons. Secondary fatty alcohols may be saturated or unsaturated and may be branched or unbranched." ; rdfs:subClassOf obo:CHEBI_24026 . obo:CHEBI_47802 a rdfs:Class ; rdfs:label "5H-dibenzo[b,f]azepine" ; rdfs:comment "A mancude organic heterotricyclic parent that consists of a seven-membered nitrogen hetrocycle fused with two benzene rings." ; rdfs:subClassOf obo:CHEBI_36416 , obo:CHEBI_47804 . obo:CHEBI_25944 a rdfs:Class ; rdfs:label "pesticide" ; rdfs:comment "Strictly, a substance intended to kill pests. In common usage, any substance used for controlling, preventing, or destroying animal, microbiological or plant pests." ; rdfs:subClassOf obo:CHEBI_33232 . obo:NCBITaxon_389126 a rdfs:Class ; rdfs:label "Bat coronavirus China 2005" ; rdfs:subClassOf obo:NCBITaxon_2664420 . a rdfs:Class ; rdfs:label "Autoimmune Diseases [Disease/Finding]" ; rdfs:subClassOf . obo:PR_000012786 a rdfs:Class ; rdfs:label "serine/threonine-protein kinase N2" ; rdfs:comment "A protein that is a translation product of the human PKN2 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:NCBITaxon_983922 a rdfs:Class ; rdfs:label "Cardioderma bat coronavirus/Kenya/KY43/2006" ; rdfs:subClassOf obo:NCBITaxon_366617 . obo:CHEBI_31690 a rdfs:Class ; rdfs:label "imatinib methanesulfonate" ; rdfs:comment "A methanesulfonate (mesylate) salt that is the monomesylate salt of imatinib. Used for treatment of chronic myelogenous leukemia and gastrointestinal stromal tumours." ; rdfs:subClassOf obo:CHEBI_38037 . obo:OBI_0002606 a rdfs:Class ; rdfs:label "nasopharyngeal swab specimen" ; rdfs:comment "A specimen that is collected with a swab from the surface of a nasopharynx." ; rdfs:subClassOf obo:OBI_0002599 . obo:GO_0051940 a rdfs:Class ; rdfs:label "regulation of catecholamine uptake involved in synaptic transmission" ; rdfs:comment "Any process that modulates the frequency, rate or extent of the directed movement of catecholamine neurotransmitters into a neuron or glial cell." ; rdfs:subClassOf obo:GO_0051049 , obo:GO_0051580 . obo:NCBITaxon_264384 a rdfs:Class ; rdfs:label "SARS coronavirus TW-YM2" ; rdfs:subClassOf obo:NCBITaxon_264370 . obo:CHEBI_37697 a rdfs:Class ; rdfs:label "indolocarbazole alkaloid" ; rdfs:subClassOf obo:CHEBI_38958 , obo:CHEBI_51915 . obo:NCBITaxon_267385 a rdfs:Class ; rdfs:label "SARS coronavirus Sin3408" ; rdfs:subClassOf obo:NCBITaxon_694009 . obo:NCBITaxon_1699336 a rdfs:Class ; rdfs:label "Myotis Bat Alphacoronavirus strain YNXY_3C" ; rdfs:subClassOf obo:NCBITaxon_366617 . obo:NCBITaxon_11128 a rdfs:Class ; rdfs:label "Bovine coronavirus" ; rdfs:subClassOf obo:NCBITaxon_694002 , obo:NCBITaxon_694003 . a rdfs:Class ; rdfs:label "Stimulate Ovulation [PE]" ; rdfs:subClassOf . a rdfs:Class ; rdfs:label "Bone Marrow Diseases [Disease/Finding]" ; rdfs:subClassOf . a rdfs:Class ; rdfs:label "Vulvovaginitis [Disease/Finding]" ; rdfs:subClassOf , . obo:NCBITaxon_864610 a rdfs:Class ; rdfs:label "Bat coronavirus BR98-14/BGR/2008" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:CHEBI_16080 a rdfs:Class ; rdfs:label "gamma-amino-beta-hydroxybutyric acid" ; rdfs:comment "A gamma-amino acid comprising 4-aminobutyric acid having a 2-hydroxy substituent." ; rdfs:subClassOf obo:CHEBI_33707 , obo:CHEBI_35969 . obo:CIDO_0000226 a rdfs:Class ; rdfs:label "SARS-CoV-2 RNA"@en ; rdfs:subClassOf obo:CIDO_0000225 . obo:OBI_0002513 a rdfs:Class ; rdfs:label "placenta specimen" ; rdfs:comment "A specimen that is derived from placenta." ; rdfs:subClassOf obo:OBI_0001479 . obo:NCBITaxon_239242 a rdfs:Class ; rdfs:label "SARS coronavirus CUHK-AG02" ; rdfs:subClassOf obo:NCBITaxon_694009 . obo:PR_Q9UF33 a rdfs:Class ; rdfs:label "ephrin type-A receptor 6 (human)" ; rdfs:comment "An ephrin type-A receptor 6 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000007126 , obo:PR_000029067 . obo:CIDO_0000615 a rdfs:Class ; rdfs:label "V143- in SARS-CoV-2 S protein"@en ; rdfs:comment "An AA mutation or AA variant that has mutated an amino acid at position 143 in S protein into a deletion." ; rdfs:subClassOf obo:CIDO_0001144 . obo:NCBITaxon_694135 a rdfs:Class ; rdfs:label "unidentified coronavirus" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:CHEBI_33661 a rdfs:Class ; rdfs:label "monocyclic compound" ; rdfs:subClassOf obo:CHEBI_33595 . obo:CIDO_0020060 a rdfs:Class ; rdfs:label "Bio-Rad Reliance SARS-CoV-2 RT-PCR Assay Kit" ; rdfs:seeAlso ; rdfs:subClassOf obo:CIDO_0000454 . a rdfs:Class ; rdfs:label "Rectal Diseases [Disease/Finding]" ; rdfs:subClassOf . a rdfs:Class ; rdfs:label "IMATINIB" ; rdfs:subClassOf . obo:PR_000007458 a rdfs:Class ; rdfs:label "tyrosine-protein kinase Fer" ; rdfs:comment "A protein that is a translation product of the human FER gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:OPMI_0000441 a rdfs:Class ; rdfs:label "biomarker role"@en ; rdfs:subClassOf obo:BFO_0000023 . obo:CIDO_0000503 a rdfs:Class ; rdfs:label "GAISASLQEILSRLD" ; rdfs:comment "A coronavirus epitope that is part of some S protein from HCoV OC43 composed of the following amino acids GAISASLQEILSRLD" ; rdfs:subClassOf obo:CIDO_0000452 . obo:SO_0000001 a rdfs:Class ; rdfs:label "region" ; rdfs:comment "A sequence_feature with an extent greater than zero. A nucleotide region is composed of bases and a polypeptide region is composed of amino acids." ; rdfs:subClassOf obo:BFO_0000031 . obo:NCBITaxon_9971 a rdfs:Class ; rdfs:label "Pholidota " ; rdfs:subClassOf obo:NCBITaxon_314145 . obo:VO_0005202 a rdfs:Class ; rdfs:label "COVID-19 subunit vaccine"@en ; rdfs:subClassOf obo:VO_0004908 . obo:CIDO_0001049 a rdfs:Class ; rdfs:label "SARS-CoV2 orf9c protein binding to human ECSIT" ; rdfs:comment "SARS-CoV2 orf9c protein binding to human ECSIT, as evidented by an affinity-purification mass spectrometry experiment" ; rdfs:subClassOf obo:CIDO_0000054 . obo:NCBITaxon_9347 a rdfs:Class ; rdfs:label "Eutheria" ; rdfs:subClassOf obo:NCBITaxon_32525 . obo:NCBITaxon_1503296 a rdfs:Class ; rdfs:label "BtRf-BetaCoV/HeB2013" ; rdfs:subClassOf obo:NCBITaxon_694009 . obo:CHEBI_57603 a rdfs:Class ; rdfs:label "ethanolaminium(1+)" ; rdfs:comment "A primary aliphatic ammonium ion that is the conjugate acid of ethanolamine arising from protonation of the primary amino function." ; rdfs:subClassOf obo:CHEBI_58001 . a rdfs:Class ; rdfs:label "Mycobacterium Infections, Atypical [Disease/Finding]" ; rdfs:subClassOf . obo:CIDO_0000447 a rdfs:Class ; rdfs:label "spike surface glycoprotein (HCoV OC43)"@en ; rdfs:comment "A surface glycoprotein of human coronavirus OC43." ; rdfs:subClassOf obo:CIDO_0000441 . obo:SO_0000418 a rdfs:Class . a rdfs:Class ; rdfs:label "Porphyrias [Disease/Finding]" ; rdfs:subClassOf , . obo:PR_000008567 a rdfs:Class ; rdfs:label "homeodomain-interacting protein kinase 2" ; rdfs:comment "A protein that is a translation product of the human HIPK2 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:CHEBI_29214 a rdfs:Class ; rdfs:label "sulfonic acid" ; rdfs:subClassOf obo:CHEBI_33402 . obo:PR_000011515 a rdfs:Class ; rdfs:label "nuclear pore complex protein Nup214" ; rdfs:comment "A protein that is a translation product of the human NUP214 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:CHEBI_32841 a rdfs:Class ; rdfs:label "D-serinium" ; rdfs:comment "The D-enantiomer of serinium." ; rdfs:subClassOf obo:CHEBI_32846 . obo:CHEBI_64558 a rdfs:Class ; rdfs:label "methionine zwitterion" ; rdfs:comment "An amino acid zwitterion arising from transfer of a proton from the carboxy to the amino group of methionine; major species at pH 7.3." ; rdfs:subClassOf obo:CHEBI_35238 . obo:PR_O14965 a rdfs:Class ; rdfs:label "aurora kinase A (human)" ; rdfs:comment "An aurora kinase A that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000004515 , obo:PR_000029067 . obo:PR_000007259 a rdfs:Class ; rdfs:label "exosome complex component RRP4" ; rdfs:comment "A protein that is a translation product of the human EXOSC2 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:PR_P63098 a rdfs:Class ; rdfs:label "calcineurin subunit B type 1 (human)" ; rdfs:comment "A calcineurin subunit B type 1 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000013150 , obo:PR_000029067 . obo:CHEBI_33246 a rdfs:Class ; rdfs:label "inorganic group" ; rdfs:comment "Any substituent group which does not contain carbon." ; rdfs:subClassOf obo:CHEBI_24433 . obo:CHEBI_33720 a rdfs:Class ; rdfs:label "carbohydrate acid" ; rdfs:subClassOf obo:CHEBI_16646 , obo:CHEBI_33575 . obo:NCBITaxon_627432 a rdfs:Class ; rdfs:label "Feline coronavirus UU11" ; rdfs:subClassOf obo:NCBITaxon_12663 . obo:CHEBI_21644 a rdfs:Class ; rdfs:label "N-acyl-L-amino acid" ; rdfs:comment "Any N-acylamino acid having L-configuration." ; rdfs:subClassOf obo:CHEBI_51569 . obo:CHEBI_76840 a rdfs:Class ; rdfs:label "EC 1.14.99.* (miscellaneous oxidoreductase acting on paired donors, with incorporation or reduction of molecular oxygen) inhibitor" ; rdfs:comment "An EC 1.14.* (oxidoreductase acting on paired donors, with incorporation or reduction of molecular oxygen) inhibitor that interferes with the action of any enzyme in the EC 1.14.99.* (miscellaneous) category." ; rdfs:subClassOf obo:CHEBI_76741 . obo:CHEBI_17272 a rdfs:Class ; rdfs:label "propionate" ; rdfs:comment "The conjugate base of propionic acid; a key precursor in lipid biosynthesis." ; rdfs:subClassOf obo:CHEBI_78113 . obo:CIDO_0020071 a rdfs:Class ; rdfs:label "CDI Enhanced COVID-19 Test" ; rdfs:seeAlso ; rdfs:subClassOf obo:CIDO_0000454 . obo:NCBITaxon_864601 a rdfs:Class ; rdfs:label "Bat coronavirus BM48-48/BGR/2008" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:CIDO_0020166 a rdfs:Class ; rdfs:label "Helix COVID-19 NGS Test" ; rdfs:seeAlso ; rdfs:subClassOf obo:CIDO_0000454 . obo:OBI_0002125 a rdfs:Class ; rdfs:label "H&E-stained fixed tissue slide specimen"@en ; rdfs:comment "A fixed tissue slide specimen that is the output of H&E slide staining."@en ; rdfs:subClassOf obo:OMIABIS_0000052 . a rdfs:Class ; rdfs:label "Caproates [Chemical/Ingredient]" ; rdfs:subClassOf , . obo:NCBITaxon_1644144 a rdfs:Class ; rdfs:label "Bat coronavirus MAH056F" ; rdfs:subClassOf obo:NCBITaxon_696098 . obo:CIDO_0001054 a rdfs:Class ; rdfs:label "SARS-CoV2 orf9c protein binding to human GPAA1" ; rdfs:comment "SARS-CoV2 orf9c protein binding to human GPAA1, as evidented by an affinity-purification mass spectrometry experiment" ; rdfs:subClassOf obo:CIDO_0000054 . obo:PR_000008256 a rdfs:Class ; rdfs:label "GRIP1-associated protein 1" ; rdfs:comment "A protein that is a translation product of the human GRIPAP1 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:NCBITaxon_622717 a rdfs:Class ; rdfs:label "Bat coronavirus Hipposideros/GhanaKwam/31/2008" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:CIDO_0000380 a rdfs:Class ; rdfs:label "SARS-CoV-2 Eta variant"@en ; rdfs:subClassOf obo:CIDO_0000407 . obo:CIDO_0020055 a rdfs:Class ; rdfs:label "BioFire Respiratory Panel 2.1" ; rdfs:seeAlso ; rdfs:subClassOf obo:CIDO_0000454 . obo:IAO_0000032 a rdfs:Class ; rdfs:label "scalar measurement datum"@en ; rdfs:comment "a scalar measurement datum is a measurement datum that is composed of two parts, numerals and a unit label."@en ; rdfs:subClassOf obo:IAO_0000109 . obo:CIDO_0000345 a rdfs:Class ; rdfs:label "host-coronavirus molecular interaction"@en ; rdfs:subClassOf obo:CIDO_0000084 . obo:VO_0001359 a rdfs:Class ; rdfs:label "carbohydrate vaccine adjuvant" ; rdfs:subClassOf obo:VO_0000580 . obo:PR_Q96Q40 a rdfs:Class ; rdfs:label "cyclin-dependent kinase 15 (human)" ; rdfs:comment "A cyclin-dependent kinase 15 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000012590 , obo:PR_000029067 . obo:CHEBI_35681 a rdfs:Class ; rdfs:label "secondary alcohol" ; rdfs:comment "A secondary alcohol is a compound in which a hydroxy group, -OH, is attached to a saturated carbon atom which has two other carbon atoms attached to it." ; rdfs:subClassOf obo:CHEBI_30879 . obo:NCBITaxon_1679924 a rdfs:Class ; rdfs:label "Coronavirus Rabbit_CoV/La06_256/Ory_cun/ESP/2006" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:CIDO_0000626 a rdfs:Class ; rdfs:label "D377Y in SARS-CoV-2 N protein" ; rdfs:comment "An AA mutation or AA variant that has mutated an amino acid at position 377 into a tyrosine in N protein." ; rdfs:subClassOf obo:CIDO_0000596 . a rdfs:Class ; rdfs:label "Giardiasis [Disease/Finding]" ; rdfs:subClassOf , . obo:CHEBI_90227 a rdfs:Class ; rdfs:label "selumetinib" ; rdfs:comment "A member of the class of benzimidazoles that is 1-methyl-1H-benzimidazole which is substituted at positions 4, 5, and 6 by fluorine, (4-bromo-2-chlorophenyl)amino, and N-(2-hydroxyethoxy)aminocarbonyl groups, respectively. It is a MEK1 and MEK2 inhibitor." ; rdfs:subClassOf obo:CHEBI_22715 , obo:CHEBI_37143 , obo:CHEBI_37149 , obo:CHEBI_50995 , obo:CHEBI_75606 , obo:CHEBI_83403 . obo:GO_0035637 a rdfs:Class ; rdfs:label "multicellular organismal signaling" ; rdfs:comment "The transfer of information occurring at the level of a multicellular organism." ; rdfs:subClassOf obo:GO_0023052 , obo:GO_0032501 . obo:OBI_1110001 a rdfs:Class ; rdfs:label "epitope"@en ; rdfs:comment "a material entity bearing the epitope role"@en ; rdfs:subClassOf obo:BFO_0000040 . obo:NCBITaxon_1346313 a rdfs:Class ; rdfs:label "Betacoronavirus BtCoV/Rhi_hip/Slo48/SLO/2009" ; rdfs:subClassOf obo:NCBITaxon_696098 . obo:PR_000005928 a rdfs:Class ; rdfs:label "cold shock domain-containing protein E1" ; rdfs:comment "A protein that is a translation product of the human CSDE1 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:CHEBI_9571 a rdfs:Class ; rdfs:label "Thiothixene" ; rdfs:subClassOf obo:CHEBI_46920 . obo:CHEBI_58001 a rdfs:Class ; rdfs:label "primary aliphatic ammonium ion" ; rdfs:comment "The conjugate acid of a primary aliphatic amine." ; rdfs:subClassOf obo:CHEBI_65296 . obo:VO_0004988 a rdfs:Class ; rdfs:label "SARS-CoV-2 protein"@en ; rdfs:subClassOf obo:PR_000000001 , obo:VO_0010754 . obo:VO_0005127 a rdfs:Class ; rdfs:label "Viral-like-particle S-MHV SARS vaccine" ; rdfs:comment "A SARS VLP vaccine made from the SARS-CoV spike protein (S) and the Nucleocapsid (N), envelope (E) and membrane (M) proteins from mouse hepatitis coronavirus (MHV)" ; rdfs:subClassOf obo:VO_0012183 . obo:NCBITaxon_1788460 a rdfs:Class ; rdfs:label "Miniopterus bat coronavirus BtCoV/3709" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:PR_000004978 a rdfs:Class ; rdfs:label "calmodulin" ; rdfs:comment "A protein that is a translation product of the human CALM1, CALM2, or CALM3 genes, 1:1 orthologs thereof, or a semi-ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:CHEBI_75998 a rdfs:Class ; rdfs:label "trametinib" ; rdfs:comment "A pyridopyrimidine that is used (as its dimethyl sulfoxide addition compound) for the treatment of patients with unresectable or metastatic melanoma with BRAF V600E or V600K mutations, and who have not received prior BRAF inhibitor treatment." ; rdfs:subClassOf obo:CHEBI_22160 , obo:CHEBI_33860 , obo:CHEBI_36820 , obo:CHEBI_37142 , obo:CHEBI_37143 , obo:CHEBI_38932 , obo:CHEBI_51454 . obo:CIDO_0000330 a rdfs:Class ; rdfs:label "VFAQVKQIYKTPPIK"@en ; rdfs:subClassOf obo:CIDO_0000314 . obo:CHEBI_35868 a rdfs:Class ; rdfs:label "hydroxy monocarboxylic acid" ; rdfs:comment "Any monocarboxylic acid which also contains a separate (alcoholic or phenolic) hydroxy substituent." ; rdfs:subClassOf obo:CHEBI_24669 , obo:CHEBI_25384 . a rdfs:Class ; rdfs:label "Retinal Diseases [Disease/Finding]" ; rdfs:subClassOf . obo:PR_000060053 a rdfs:Class ; rdfs:label "uncharacterized protein C1orf50" ; rdfs:comment "A protein that is a translation product of the human C1orf50 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:NCBITaxon_1225484 a rdfs:Class ; rdfs:label "Bat coronavirus Gabon/390/2009" ; rdfs:subClassOf obo:NCBITaxon_2664420 . a rdfs:Class ; rdfs:label "Child [Disease/Finding]" ; rdfs:subClassOf . obo:CHEBI_38482 a rdfs:Class ; rdfs:label "indole alkaloid fundamental parent" ; rdfs:subClassOf obo:CHEBI_35506 . obo:UBERON_0002032 a rdfs:Class ; rdfs:label "areola" ; rdfs:comment "Subdivision of breast which consists of skin, connective tissue and smooth muscle bundle and modified sebaceous glands and which surrounds the nipple." ; rdfs:subClassOf obo:UBERON_0000465 . obo:NCBITaxon_267396 a rdfs:Class ; rdfs:label "SARS coronavirus Sin846" ; rdfs:subClassOf obo:NCBITaxon_694009 . obo:PR_000001107 a rdfs:Class ; rdfs:label "D(1)-like dopamine receptor" ; rdfs:comment "A dopamine receptor that is a product of the DRD1 or DRD5 gene. The active form binds dopamine and its activity is mediated by G proteins that cause activation of adenylate cyclase." ; rdfs:subClassOf obo:PR_000044633 . obo:CHEBI_57762 a rdfs:Class ; rdfs:label "L-valine zwitterion" ; rdfs:comment "An L-alpha-amino acid zwitterion obtained by transfer of a proton from the carboxy to the amino group of L-valine; major species at pH 7.3." ; rdfs:subClassOf obo:CHEBI_59869 . obo:PR_P00750 a rdfs:Class ; rdfs:label "tissue-type plasminogen activator (human)" ; rdfs:comment "A tissue-type plasminogen activator that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000012825 , obo:PR_000029067 . obo:NCBITaxon_1699318 a rdfs:Class ; rdfs:label "Myotis Bat Alphacoronavirus strain MJ_27C" ; rdfs:subClassOf obo:NCBITaxon_366617 . obo:CIDO_0000389 a rdfs:Class ; rdfs:label "K18-hACE2 transgenic mouse"@en ; rdfs:comment "A transgenic mouse that expresses the SARS-CoV receptor (human angiotensin-converting enzyme 2 [hACE2]) in airway and other epithelia, which can develop a rapidly lethal infection after intranasal inoculation with a human strain of the virus." ; rdfs:subClassOf obo:CIDO_0000388 . obo:CHEBI_23132 a rdfs:Class ; rdfs:label "chlorobenzenes" ; rdfs:comment "Any organochlorine compound containing a benzene ring which is substituted by one or more chlorines." ; rdfs:subClassOf obo:CHEBI_22712 , obo:CHEBI_36683 . obo:PR_000004463 a rdfs:Class ; rdfs:label "ATP synthase subunit g, mitochondrial" ; rdfs:comment "A protein that is a translation product of the human ATP5MG gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:HP_0004755 a rdfs:Class ; rdfs:label "Supraventricular tachycardia" ; rdfs:comment "Supraventricular tachycardia (SVT) is an abnormally increased heart rate (over 100 beats per minute at rest) with origin above the level of the ventricles." ; rdfs:subClassOf obo:HP_0001649 , obo:HP_0005115 . obo:NCBITaxon_385683 a rdfs:Class ; rdfs:label "SARS coronavirus CS21" ; rdfs:subClassOf obo:NCBITaxon_694009 . obo:PR_000050025 a rdfs:Class ; rdfs:label "angiotensinogenase" ; rdfs:comment "A protein that is a translation product of the mouse Ren1 or Ren2 genes, 1:1 orthologs thereof, or a semi-ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:OAE_0000418 a rdfs:Class ; rdfs:label "neuropathy AE" ; rdfs:comment "a nervous system AE that shows a damage to or disease affecting the nerves." ; rdfs:subClassOf obo:OAE_0000570 . obo:NCBITaxon_1788431 a rdfs:Class ; rdfs:label "Bat coronavirus RsBtCoV/3716" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:PR_000002105 a rdfs:Class ; rdfs:label "thrombomodulin" ; rdfs:comment "A thrombomodulin-like receptor that is a translation product of the human THBD gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000001938 . obo:NCBITaxon_461304 a rdfs:Class ; rdfs:label "Rocky Mountain Bat Coronavirus 11" ; rdfs:subClassOf obo:NCBITaxon_366617 . obo:NCBITaxon_264379 a rdfs:Class ; rdfs:label "SARS coronavirus TW-GD2" ; rdfs:subClassOf obo:NCBITaxon_264370 . obo:VO_0001081 a rdfs:Class ; rdfs:label "adenovirus serotype 5 vaccine vector" ; rdfs:comment "an adenovirus vaccine vector that uses an Adenovirus serotype 5 strain." ; rdfs:subClassOf obo:VO_0000136 . obo:CHEBI_22153 a rdfs:Class ; rdfs:label "acaricide" ; rdfs:comment "A substance used to destroy pests of the subclass Acari (mites and ticks)." ; rdfs:subClassOf obo:CHEBI_25944 . obo:PR_P0DTF1 a rdfs:Class ; rdfs:label "putative ORF3b protein (SARS-CoV-2)" ; rdfs:comment "A protein that is a translation product of the ORF3b gene in SARS-CoV-2." ; rdfs:subClassOf obo:PR_000050262 . obo:CIDO_0000514 a rdfs:Class ; rdfs:label "CVDLHNKINLCDDPE" ; rdfs:comment "A coronavirus epitope that is part of some S protein from HCoV NL63 composed of the following amino acids CVDLHNKINLCDDPE" ; rdfs:subClassOf obo:CIDO_0000449 . obo:CHEBI_38179 a rdfs:Class ; rdfs:label "monocyclic heteroarene" ; rdfs:subClassOf obo:CHEBI_33833 . a rdfs:Class ; rdfs:label "interferon beta-1b [Chemical/Ingredient]" ; rdfs:subClassOf . obo:CHEBI_16733 a rdfs:Class ; rdfs:label "D-alpha-amino acid" ; rdfs:subClassOf obo:CHEBI_83925 . obo:CHEBI_2955 a rdfs:Class ; rdfs:label "azithromycin" ; rdfs:comment "A macrolide antibiotic useful for the treatment of bacterial infections." ; rdfs:subClassOf obo:CHEBI_25105 . obo:NCBITaxon_1346297 a rdfs:Class ; rdfs:label "Betacoronavirus BtCoV/Rhi_eur/BB98-92/BGR/2008" ; rdfs:subClassOf obo:NCBITaxon_696098 . a rdfs:Class ; rdfs:label "Fatty Acids [Chemical/Ingredient]" ; rdfs:subClassOf . a rdfs:Class ; rdfs:label "Alkaloids [Chemical/Ingredient]" ; rdfs:subClassOf . obo:CHEBI_33854 a rdfs:Class ; rdfs:label "aromatic alcohol" ; rdfs:comment "Any alcohol in which the alcoholic hydroxy group is attached to a carbon which is itself bonded to an aromatic ring." ; rdfs:subClassOf obo:CHEBI_30879 , obo:CHEBI_33659 . obo:CHEBI_50744 a rdfs:Class ; rdfs:label "citrate salt" ; rdfs:comment "A salt of citric acid." ; rdfs:subClassOf obo:CHEBI_24868 . obo:PR_000013390 a rdfs:Class ; rdfs:label "26S proteasome non-ATPase regulatory subunit 8" ; rdfs:comment "A protein that is a translation product of the human PSMD8 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:CHEBI_36916 a rdfs:Class ; rdfs:label "cation" ; rdfs:comment "A monoatomic or polyatomic species having one or more elementary charges of the proton." ; rdfs:subClassOf obo:CHEBI_24870 . a rdfs:Class ; rdfs:label "Intracranial Hemorrhages [Disease/Finding]" ; rdfs:subClassOf , . obo:NCBITaxon_441976 a rdfs:Class ; rdfs:label "Asian leopard cat coronavirus Guangxi/F230/2006" ; rdfs:subClassOf obo:NCBITaxon_441985 . obo:DRON_00013976 a rdfs:Class ; rdfs:label "terconazole" ; rdfs:subClassOf obo:OBI_0000047 . obo:CHEBI_27027 a rdfs:Class ; rdfs:label "micronutrient" ; rdfs:comment "Any nutrient required in small quantities by organisms throughout their life in order to orchestrate a range of physiological functions." ; rdfs:subClassOf obo:CHEBI_33284 . obo:CHEBI_70663 a rdfs:Class ; rdfs:label "(2S)-8-methylpinocembrin" ; rdfs:comment "A dihydroxyflavanone that is pinocembrin substituted by a methyl group at position 8. It has been isolated from the buds of Cleistocalyx operculatus." ; rdfs:subClassOf obo:CHEBI_140377 , obo:CHEBI_38749 . obo:CHEBI_64554 a rdfs:Class ; rdfs:label "tryptophan zwitterion" ; rdfs:comment "An amino acid zwitterion obtained by transfer of a proton from the carboxy to the amino group of tryptophan; major species at pH 7.3." ; rdfs:subClassOf obo:CHEBI_35238 . obo:NCBITaxon_1699317 a rdfs:Class ; rdfs:label "Myotis Bat Alphacoronavirus strain MJ_26C" ; rdfs:subClassOf obo:NCBITaxon_366617 . a rdfs:Class ; rdfs:label "Shock [Disease/Finding]" ; rdfs:subClassOf . obo:CHEBI_30488 a rdfs:Class ; rdfs:label "sulfonium" ; rdfs:subClassOf obo:CHEBI_26830 , obo:CHEBI_33535 , obo:CHEBI_50313 . obo:CHEBI_22645 a rdfs:Class ; rdfs:label "arenecarboxamide" ; rdfs:comment "A monocarboxylic acid amide in which the amide linkage is bonded directly to an arene ring system." ; rdfs:subClassOf obo:CHEBI_29347 , obo:CHEBI_62733 . obo:BFO_0000148 a rdfs:Class ; rdfs:label "zero-dimensional temporal region"@en ; rdfs:subClassOf obo:BFO_0000008 . obo:PR_000049859 a rdfs:Class ; rdfs:label "calmodulin (human)" ; rdfs:comment "A calmodulin that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000004978 , obo:PR_000029067 . obo:CIDO_0020223 a rdfs:Class ; rdfs:label "ORAcollect∙RNA OR-100 and ORAcollect∙RNA ORE-100 saliva collection devices" ; rdfs:seeAlso ; rdfs:subClassOf obo:CIDO_0000455 . obo:PR_Q9HD40 a rdfs:Class ; rdfs:label "O-phosphoseryl-tRNA(Sec) selenium transferase (human)" ; rdfs:comment "An O-phosphoseryl-tRNA(Sec) selenium transferase that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000014647 , obo:PR_000029067 . obo:CHEBI_33694 a rdfs:Class ; rdfs:label "biomacromolecule" ; rdfs:comment "A macromolecule formed by a living organism." ; rdfs:subClassOf obo:CHEBI_33839 , obo:CHEBI_50860 . obo:DOID_0080599 a rdfs:Class ; rdfs:label "Coronavirus infectious disease"@en ; rdfs:comment "A viral infectious disease that has_material_basis_in Coronavirus." ; rdfs:subClassOf obo:DOID_934 . obo:GO_0043552 a rdfs:Class ; rdfs:label "positive regulation of phosphatidylinositol 3-kinase activity" ; rdfs:comment "Any process that activates or increases the frequency, rate or extent of phosphatidylinositol 3-kinase activity." ; rdfs:subClassOf obo:GO_0043550 , obo:GO_0090218 . obo:DOID_0070084 a rdfs:Class ; rdfs:label "schizophrenia 8" ; rdfs:comment "A schizophrenia that has_material_basis_in an autosomal dominant mutation of SCZD8 on chromosome 18p." ; rdfs:subClassOf obo:DOID_0050736 , obo:DOID_5419 . obo:CIDO_0001067 a rdfs:Class ; rdfs:label "SARS-CoV2 orf9c protein binding to human TMEM97" ; rdfs:comment "SARS-CoV2 orf9c protein binding to human TMEM97, as evidented by an affinity-purification mass spectrometry experiment" ; rdfs:subClassOf obo:CIDO_0000054 . obo:DOID_0060166 a rdfs:Class ; rdfs:label "bipolar ll disorder" ; rdfs:comment "A bipolar disorder that is characterized by at least one hypomanic episode and at least one major depressive episode; with this disorder, depressive episodes are more frequent and more intense than manic episodes." ; rdfs:subClassOf obo:DOID_3312 . obo:CHEBI_34848 a rdfs:Class ; rdfs:label "mevastatin" ; rdfs:comment "A carboxylic ester that is pravastatin that is lacking the allylic hydroxy group. A hydroxymethylglutaryl-CoA reductase inhibitor (statin) isolated from Penicillium citrinum and from Penicillium brevicompactum, its clinical use as a lipid-regulating drug ceased following reports of toxicity in animals." ; rdfs:subClassOf obo:CHEBI_142348 , obo:CHEBI_26188 , obo:CHEBI_33308 , obo:CHEBI_75885 , obo:CHEBI_87632 . obo:CHEBI_51026 a rdfs:Class ; rdfs:label "macrocycle" ; rdfs:comment "A cyclic compound containing nine or more atoms as part of the cyclic system." ; rdfs:subClassOf obo:CHEBI_33595 , obo:CHEBI_33839 . obo:PR_000015292 a rdfs:Class ; rdfs:label "sphingomyelin phosphodiesterase" ; rdfs:comment "A protein that is a translation product of the human SMPD1 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:PR_O43169 a rdfs:Class ; rdfs:label "cytochrome b5 type B (human)" ; rdfs:comment "A cytochrome b5 type B that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000006079 , obo:PR_000029067 . obo:VO_0005168 a rdfs:Class ; rdfs:label "CVnCoV" ; rdfs:comment "A SARS-CoV-2 mRNA vaccine developed by CureVac AG and CEPI." ; rdfs:subClassOf obo:VO_0005198 . obo:PR_000001616 a rdfs:Class ; rdfs:label "muscarinic acetylcholine receptor M4" ; rdfs:comment "A muscarinic acetylcholine receptor that is a translation product of the human CHRM4 gene or a 1:1 ortholog thereof. This receptor is expressed in the central nervous system." ; rdfs:subClassOf obo:PR_000001488 . a rdfs:Class ; rdfs:label "Colorectal Neoplasms [Disease/Finding]" ; rdfs:subClassOf , , . obo:CHEBI_48382 a rdfs:Class ; rdfs:label "imidazopyridazine" ; rdfs:comment "An organic heterobicyclic compound that consists of an imidazole ring ortho-fused to a pyridazine ring." ; rdfs:subClassOf obo:CHEBI_27171 , obo:CHEBI_38101 . obo:CHEBI_24669 a rdfs:Class ; rdfs:label "hydroxy carboxylic acid" ; rdfs:comment "Any carboxylic acid with at least one hydroxy group." ; rdfs:subClassOf obo:CHEBI_33575 , obo:CHEBI_33822 . obo:CHEBI_24870 a rdfs:Class ; rdfs:label "ion" ; rdfs:comment "A molecular entity having a net electric charge." ; rdfs:subClassOf obo:CHEBI_23367 . obo:CHEBI_35660 a rdfs:Class ; rdfs:label "HIV protease inhibitor" ; rdfs:comment "An inhibitor of HIV protease, an enzyme required for production of proteins needed for viral assembly." ; rdfs:subClassOf obo:CHEBI_37670 , obo:CHEBI_64946 . a rdfs:Class ; rdfs:label "Helminthiasis [Disease/Finding]" ; rdfs:subClassOf . obo:CIDO_0000637 a rdfs:Class ; rdfs:label "I3758V in SARS-CoV-2 pp1a protein" ; rdfs:comment "An AA mutation or AA variant that has mutated an amino acid at position 3758 into a valine in pp1a." ; rdfs:subClassOf obo:CIDO_0001074 . obo:PR_O43353 a rdfs:Class ; rdfs:label "receptor-interacting serine/threonine-protein kinase 2 (human)" ; rdfs:comment "A receptor-interacting serine/threonine-protein kinase 2 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000014023 , obo:PR_000029067 . obo:NCBITaxon_255729 a rdfs:Class ; rdfs:label "SARS coronavirus Sino3-11" ; rdfs:subClassOf obo:NCBITaxon_694009 . obo:PATO_0000384 a rdfs:Class ; rdfs:label "male" ; rdfs:comment "A biological sex quality inhering in an individual or a population whose sex organs contain only male gametes." ; rdfs:subClassOf obo:PATO_0001894 . obo:PR_Q9P0L2 a rdfs:Class ; rdfs:label "serine/threonine-protein kinase MARK1 (human)" ; rdfs:comment "A serine/threonine-protein kinase MARK1 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000010186 , obo:PR_000029067 . obo:CHEBI_17578 a rdfs:Class ; rdfs:label "toluene" ; rdfs:comment "The simplest member of the class toluenes consisting of a benzene core which bears a single methyl substituent." ; rdfs:subClassOf obo:CHEBI_134179 , obo:CHEBI_27024 , obo:CHEBI_38975 . obo:CHEBI_22653 a rdfs:Class ; rdfs:label "asparagine" ; rdfs:comment "An alpha-amino acid in which one of the hydrogens attached to the alpha-carbon of glycine is substituted by a 2-amino-2-oxoethyl group." ; rdfs:subClassOf obo:CHEBI_26167 , obo:CHEBI_33704 , obo:CHEBI_35735 . obo:NCBITaxon_1788494 a rdfs:Class ; rdfs:label "Rhinolophus bat coronavirus BtCoV/4060" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:CHEBI_61120 a rdfs:Class ; rdfs:label "nucleobase-containing molecular entity" ; rdfs:comment "Any compound that has a nucleobase as a part." ; rdfs:subClassOf obo:CHEBI_33833 , obo:CHEBI_51143 . obo:CIDO_0000619 a rdfs:Class ; rdfs:label "AA variant in SARS-CoV-2 M protein"@en ; rdfs:subClassOf obo:CIDO_0000237 . obo:PR_000011407 a rdfs:Class ; rdfs:label "mineralocorticoid receptor" ; rdfs:comment "A protein that is a translation product of the human NR3C2 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:PR_Q04726 a rdfs:Class ; rdfs:label "transducin-like enhancer protein 3 (human)" ; rdfs:comment "A transducin-like enhancer protein 3 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000016374 , obo:PR_000029067 . a rdfs:Class ; rdfs:label "Neisseriaceae Infections [Disease/Finding]" ; rdfs:subClassOf . obo:NCBITaxon_622712 a rdfs:Class ; rdfs:label "Bat coronavirus Hipposideros/GhanaKwam/20/2008" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:CIDO_0000525 a rdfs:Class ; rdfs:label "NFVALIPDYAKILVN" ; rdfs:comment "A coronavirus epitope that is part of some S protein from HCoV HKU1 composed of the following amino acids NFVALIPDYAKILVN" ; rdfs:subClassOf obo:CIDO_0000450 . obo:PR_Q9BYT3 a rdfs:Class ; rdfs:label "serine/threonine-protein kinase 33 (human)" ; rdfs:comment "A serine/threonine-protein kinase 33 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000015751 , obo:PR_000029067 . a rdfs:Class ; rdfs:label "Flecainide [Chemical/Ingredient]" ; rdfs:subClassOf . obo:CHEBI_63944 a rdfs:Class ; rdfs:label "macrocyclic lactone" ; rdfs:comment "Any lactone in which the cyclic carboxylic ester group forms a part of a cyclic macromolecule." ; rdfs:subClassOf obo:CHEBI_25000 , obo:CHEBI_51026 . obo:CIDO_0000775 a rdfs:Class ; rdfs:label "SARS-CoV2 M protein binding to human YIF1A" ; rdfs:comment "SARS-CoV2 M protein binding to human YIF1A, as evidented by an affinity-purification mass spectrometry experiment" ; rdfs:subClassOf obo:CIDO_0000055 . a rdfs:Class ; rdfs:label "Arrhythmias, Cardiac [Disease/Finding]" ; rdfs:subClassOf , . obo:PR_P61927 a rdfs:Class ; rdfs:label "60S ribosomal protein L37 (human)" ; rdfs:comment "A 60S ribosomal protein L37 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000014222 , obo:PR_000029067 . obo:CHEBI_35416 a rdfs:Class ; rdfs:label "alpha-amino-acid residue anion" ; rdfs:subClassOf obo:CHEBI_64898 . obo:CHEBI_67194 a rdfs:Class ; rdfs:label "cannabinoid" ; rdfs:comment "A diverse group of pharmacologically active secondary metabolite characteristic to Cannabis plant as well as produced naturally in the body by humans and animals. Cannabinoids contain oxygen as a part of the heterocyclic ring or in the form of various functional groups. They are subdivided on the basis of their origin." ; rdfs:subClassOf obo:CHEBI_36963 . obo:CHEBI_6942 a rdfs:Class ; rdfs:label "minoxidil" ; rdfs:comment "A pyrimidine N-oxide that is pyrimidine-2,4-diamine 3-oxide substituted by a piperidin-1-yl group at position 6." ; rdfs:subClassOf obo:CHEBI_26151 , obo:CHEBI_38338 , obo:CHEBI_50698 . obo:CIDO_0000093 a rdfs:Class ; rdfs:label "SARS-CoV replication inside cell"@en ; rdfs:comment "A coronavirus-host interaction by which the SARS-CoV virus replicates inside the host cell" ; rdfs:subClassOf obo:CIDO_0000086 . obo:PR_000012476 a rdfs:Class ; rdfs:label "myomegalin" ; rdfs:comment "A protein that is a translation product of the human PDE4DIP gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:NCBITaxon_1532174 a rdfs:Class ; rdfs:label "Alphacoronavirus BtCoV/NCL_MCO1/Mop_con/RSA/2012" ; rdfs:subClassOf obo:NCBITaxon_366617 . obo:PR_000004806 a rdfs:Class ; rdfs:label "bromodomain-containing protein 2" ; rdfs:comment "A protein that is a translation product of the human BRD2 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:CHEBI_131605 a rdfs:Class ; rdfs:label "dicarboxylic acid monoester(1-)" ; rdfs:comment "A carboxylic acid anion resulting from the deprotonation of the carboxy group of a dicarboxylic acid monoester." ; rdfs:subClassOf obo:CHEBI_29067 . obo:VariO_0325 a rdfs:Class ; rdfs:label "protein variation classification" ; rdfs:comment "Classification of protein variation." ; rdfs:subClassOf obo:VariO_0012 . obo:NCBITaxon_1699356 a rdfs:Class ; rdfs:label "Rousettus Bat Betacoronavirus strain ML_7I" ; rdfs:subClassOf obo:NCBITaxon_696098 . obo:NCBITaxon_1788426 a rdfs:Class ; rdfs:label "Bat coronavirus MsBtCoV/4039" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:VO_0005264 a rdfs:Class ; rdfs:label "authorized COVID-19 vaccine"@en ; rdfs:comment "A COVID-19 vaccine that is authorized for emergent use, which is typically authorized based on an Emergency Use Authorization (EUA)." ; rdfs:subClassOf obo:VO_0004908 . obo:NCBITaxon_669204 a rdfs:Class ; rdfs:label "Alpaca coronavirus CA08-1/2008" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:CHEBI_50864 a rdfs:Class ; rdfs:label "insulin-sensitizing drug" ; rdfs:comment "An agent which overcomes insulin resistance by activation of the peroxisome proliferator activated receptor gamma (PPAR-gamma)." ; rdfs:subClassOf obo:CHEBI_35526 , obo:CHEBI_48705 , obo:CHEBI_70781 . obo:UBERON_0006314 a rdfs:Class ; rdfs:label "bodily fluid" ; rdfs:comment "Liquid components of living organisms. includes fluids that are excreted or secreted from the body as well as body water that normally is not." ; rdfs:subClassOf obo:UBERON_0000463 . obo:OBI_0002610 a rdfs:Class ; rdfs:label "tongue swab specimen" ; rdfs:comment "A specimen that is collected with a swab from the surface of a tongue." ; rdfs:subClassOf obo:OBI_0002599 . obo:CIDO_0000157 a rdfs:Class ; rdfs:label "SARS-CoV transmission"@en ; rdfs:subClassOf obo:CIDO_0000155 . obo:PR_000011212 a rdfs:Class ; rdfs:label "ninein" ; rdfs:comment "A protein that is a translation product of the human NIN gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . a rdfs:Class ; rdfs:label "Heart Valve Diseases [Disease/Finding]" ; rdfs:subClassOf . obo:GO_0051251 a rdfs:Class ; rdfs:label "positive regulation of lymphocyte activation" ; rdfs:comment "Any process that activates or increases the frequency, rate or extent of lymphocyte activation." ; rdfs:subClassOf obo:GO_0002696 , obo:GO_0051249 . obo:CIDO_0000425 a rdfs:Class ; rdfs:label "SARS diagnostic process"@en ; rdfs:comment "A diagnostic process for detecting SARS from a patient" ; rdfs:subClassOf obo:CIDO_0000423 . obo:HP_0006696 a rdfs:Class ; rdfs:label "Polymorphic and polytopic ventricular extrasystoles" ; rdfs:subClassOf obo:HP_0006682 . obo:CIDO_0000828 a rdfs:Class ; rdfs:label "SARS-CoV2 nsp13 protein binding to human CEP135" ; rdfs:comment "SARS-CoV2 nsp13 protein binding to human CEP135, as evidented by an affinity-purification mass spectrometry experiment" ; rdfs:subClassOf obo:CIDO_0000058 . obo:VO_0005234 a rdfs:Class ; rdfs:label "NBP2001"@en ; rdfs:comment "A SARS-CoV-2 protein subunit vaccine by SK Bioscience" ; rdfs:subClassOf obo:VO_0005202 . obo:CHEBI_60039 a rdfs:Class ; rdfs:label "L-proline zwitterion" ; rdfs:comment "The zwitterion formed from L-proline by proton transfer from the carboxy group to the ring nitrogen. It is the predominant species at physiological pH." ; rdfs:subClassOf obo:CHEBI_35238 . obo:CHEBI_70782 a rdfs:Class ; rdfs:label "PPARalpha agonist" ; rdfs:comment "A PPAR modulator which activates the peroxisome proliferator-activated receptor-alpha." ; rdfs:subClassOf obo:CHEBI_48705 , obo:CHEBI_70781 . a rdfs:Class ; rdfs:label "Decreased Fibroblast Migration [PE]" ; rdfs:subClassOf . obo:CHEBI_48358 a rdfs:Class ; rdfs:label "polar aprotic solvent" ; rdfs:comment "A solvent with a comparatively high relative permittivity (or dielectric constant), greater than ca. 15, and a sizable permanent dipole moment, that cannot donate suitably labile hydrogen atoms to form strong hydrogen bonds." ; rdfs:subClassOf obo:CHEBI_48354 , obo:CHEBI_48357 . obo:CIDO_0001076 a rdfs:Class ; rdfs:label "AA variant in SARS-CoV-2 nsp5 protein"@en ; rdfs:comment "An AA variant in SARS-CoV-2 nsp8 protein. Equivalent to an AA variant in SARS-CoV-2 rep 1ab with an AA position of 3241 - 3546." ; rdfs:subClassOf obo:CIDO_0000714 . obo:CHEBI_33659 a rdfs:Class ; rdfs:label "organic aromatic compound" ; rdfs:subClassOf obo:CHEBI_33655 , obo:CHEBI_33832 . obo:NCBITaxon_875613 a rdfs:Class ; rdfs:label "Bat coronavirus HKU9-10-2" ; rdfs:subClassOf obo:NCBITaxon_694006 . obo:OBI_0002548 a rdfs:Class ; rdfs:label "omentum specimen" ; rdfs:comment "A specimen that is derived from omentum." ; rdfs:subClassOf obo:OBI_0001479 . obo:CHEBI_37605 a rdfs:Class ; rdfs:label "octadec-9-ene" ; rdfs:subClassOf obo:CHEBI_37606 . obo:CHEBI_35457 a rdfs:Class ; rdfs:label "EC 3.4.15.1 (peptidyl-dipeptidase A) inhibitor" ; rdfs:comment "An EC 3.4.15.* (peptidyl-dipeptidase) inhibitor that interferes with the action of peptidyl-dipeptidase A (EC 3.4.15.1)." ; rdfs:subClassOf obo:CHEBI_35674 , obo:CHEBI_76782 . obo:CHEBI_35819 a rdfs:Class ; rdfs:label "branched-chain fatty acid" ; rdfs:comment "Any fatty acid in which the parent hydrocarbon chain has one or more alkyl substituents; a common component in animal and bacterial lipids. The fatty acyl chain is usually saturated and the substituent a methyl group; however, unsaturated BCFAs are found in marine animals, and branches other than methyl are found in microbial lipids." ; rdfs:subClassOf obo:CHEBI_35366 . obo:CHEBI_51751 a rdfs:Class ; rdfs:label "enamide" ; rdfs:comment "An alpha,beta-unsaturated carboxylic acid amide of general formula R(1)R(2)C=CR(3)-C(=O)NR(4)R(5) in which the amide C=O function is conjugated to a C=C double bond at the alpha,beta position." ; rdfs:subClassOf obo:CHEBI_51750 , obo:CHEBI_78840 . obo:NCBITaxon_455415 a rdfs:Class ; rdfs:label "unclassified Coronavirus group 2b" ; rdfs:subClassOf obo:NCBITaxon_447206 . a rdfs:Class ; rdfs:label "Cellular Growth Phase Arrest [PE]" ; rdfs:subClassOf . obo:NCBITaxon_681874 a rdfs:Class ; rdfs:label "Kenya bat coronavirus BtKY29" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:CIDO_0020093 a rdfs:Class ; rdfs:label "COVID-19 ELISA pan-Ig Antibody Test" ; rdfs:seeAlso ; rdfs:subClassOf obo:CIDO_0000454 . obo:CIDO_0000659 a rdfs:Class ; rdfs:label "A67V in SARS-CoV-2 S protein" ; rdfs:comment "An AA mutation or AA variant that has mutated an amino acid at position 67 into a valine in S protein." ; rdfs:subClassOf obo:CIDO_0000594 . obo:CHEBI_35427 a rdfs:Class ; rdfs:label "ortho-fused polycyclic hydrocarbon" ; rdfs:subClassOf obo:CHEBI_33637 . obo:CHEBI_13643 a rdfs:Class ; rdfs:label "glycol" ; rdfs:comment "A diol in which the two hydroxy groups are on different carbon atoms, usually but not necessarily adjacent." ; rdfs:subClassOf obo:CHEBI_23824 . obo:PR_Q9H3N8 a rdfs:Class ; rdfs:label "histamine H4 receptor (human)" ; rdfs:comment "An H4 histamine receptor that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000001565 , obo:PR_000029067 . obo:GO_0007628 a rdfs:Class ; rdfs:label "adult walking behavior" ; rdfs:comment "The behavior of an adult relating to the progression of that organism along the ground by the process of lifting and setting down each leg." ; rdfs:subClassOf obo:GO_0007626 , obo:GO_0008344 . obo:CIDO_0000716 a rdfs:Class ; rdfs:label "P314F in SARS-CoV-2 pp1b protein"@en ; rdfs:comment "An AA mutation or AA variant that has mutated an amino acid at position 314 into a phenylalanine in pp1b." ; rdfs:subClassOf obo:CIDO_0000715 , obo:CIDO_0001083 . obo:NCBITaxon_1429861 a rdfs:Class ; rdfs:label "Betacoronavirus Pipistrellus kuhlii/Italy/206645-63/2011" ; rdfs:subClassOf obo:NCBITaxon_696098 . obo:CHEBI_23697 a rdfs:Class ; rdfs:label "dichlorobenzene" ; rdfs:comment "Any member of the class of chlorobenzenes carrying two chloro groups at unspecified positions." ; rdfs:subClassOf obo:CHEBI_23132 . obo:NCBITaxon_258967 a rdfs:Class ; rdfs:label "SARS coronavirus TW4" ; rdfs:subClassOf obo:NCBITaxon_694009 . obo:CHEBI_33847 a rdfs:Class ; rdfs:label "monocyclic arene" ; rdfs:comment "A monocyclic aromatic hydrocarbon." ; rdfs:subClassOf obo:CHEBI_33658 . obo:NCBITaxon_1788471 a rdfs:Class ; rdfs:label "Miniopterus bat coronavirus BtCoV/4001-1" ; rdfs:subClassOf obo:NCBITaxon_2664420 . a rdfs:Class ; rdfs:subClassOf obo:VO_0004990 . obo:GO_0046474 a rdfs:Class ; rdfs:label "glycerophospholipid biosynthetic process" ; rdfs:comment "The chemical reactions and pathways resulting in the formation of glycerophospholipids, any derivative of glycerophosphate that contains at least one O-acyl, O-alkyl, or O-alkenyl group attached to the glycerol residue." ; rdfs:subClassOf obo:GO_0006650 , obo:GO_0008654 , obo:GO_0045017 . obo:NCBITaxon_305406 a rdfs:Class ; rdfs:label "SARS coronavirus B012" ; rdfs:subClassOf obo:NCBITaxon_694009 . obo:OBI_0000406 a rdfs:Class ; rdfs:label "PCR product"@en ; rdfs:comment "is double stranded DNA that is the specified output of a polymerase chain reaction"@en ; rdfs:subClassOf obo:CHEBI_4705 , obo:OBI_0000809 . obo:NCBITaxon_1541207 a rdfs:Class ; rdfs:label "Bat Hp-betacoronavirus/Zhejiang2013-2" ; rdfs:subClassOf obo:NCBITaxon_696098 . obo:VO_0005347 a rdfs:Class ; rdfs:label "ARCT-154"@en ; rdfs:comment "A SARS-CoV-2 RNA vaccine by Arcturus Therapeutics, Inc." ; rdfs:subClassOf obo:VO_0005198 . obo:DOID_2945 a rdfs:Class ; rdfs:label "severe acute respiratory syndrome" ; rdfs:comment "A Coronavirus infection that results_in infection located_in respiratory tract, has_material_basis_in SARS coronavirus (SARS-CoV), which is transmitted_by droplet spread of respiratory secretions, transmitted_by ingestion of contaminated food, or transmitted_by fomites. The infection has_symptom fever, has_symptom headache, has_symptom body aches, has_symptom dry cough, and has_symptom hypoxia." ; rdfs:subClassOf obo:DOID_0080599 . obo:NCBITaxon_2023657 a rdfs:Class ; rdfs:label "Pipistrellus bat alphacoronavirus" ; rdfs:subClassOf obo:NCBITaxon_366617 . obo:CIDO_0001056 a rdfs:Class ; rdfs:label "SARS-CoV2 orf9c protein binding to human NDUFAF1" ; rdfs:comment "SARS-CoV2 orf9c protein binding to human NDUFAF1, as evidented by an affinity-purification mass spectrometry experiment" ; rdfs:subClassOf obo:CIDO_0000054 . obo:NCBITaxon_1346292 a rdfs:Class ; rdfs:label "Betacoronavirus BtCoV/KCR155/Pte_par/CRC/2012" ; rdfs:subClassOf obo:NCBITaxon_696098 . a rdfs:Class ; rdfs:label "Genital Neoplasms, Female [Disease/Finding]" ; rdfs:subClassOf . obo:CHEBI_17544 a rdfs:Class ; rdfs:label "hydrogencarbonate" ; rdfs:comment "The carbon oxoanion resulting from the removal of a proton from carbonic acid." ; rdfs:subClassOf obo:CHEBI_35604 . obo:GO_0071900 a rdfs:Class ; rdfs:label "regulation of protein serine/threonine kinase activity" ; rdfs:comment "Any process that modulates the rate, frequency, or extent of protein serine/threonine kinase activity." ; rdfs:subClassOf obo:GO_0045859 . obo:PR_P0DP23 a rdfs:Class ; rdfs:label "calmodulin-1 (human)" ; rdfs:comment "A calmodulin (human) that is a translation product of the CALM1 gene." ; rdfs:subClassOf obo:PR_000049859 . obo:CIDO_0000309 a rdfs:Class ; rdfs:label "GVFGVNLRTNFTIKG"@en ; rdfs:subClassOf obo:CIDO_0000449 . obo:OBI_0000112 a rdfs:Class ; rdfs:label "specimen role"@en ; rdfs:comment "a role borne by a material entity that is gained during a specimen collection process and that can be realized by use of the specimen in an investigation"@en ; rdfs:subClassOf obo:BFO_0000023 . a rdfs:Class ; rdfs:label "Trichuriasis [Disease/Finding]" ; rdfs:subClassOf . obo:CHEBI_37153 a rdfs:Class ; rdfs:label "EC 3.1.3.16 (phosphoprotein phosphatase) inhibitor" ; rdfs:comment "Any EC 3.1.3.* (phosphoric monoester hydrolase) inhibitor that interferes with the action of phosphoprotein phosphatase (EC 3.1.3.16)." ; rdfs:subClassOf obo:CHEBI_76775 . obo:NCBITaxon_11135 a rdfs:Class ; rdfs:label "Feline infectious peritonitis virus" ; rdfs:subClassOf obo:NCBITaxon_12663 . obo:CHEBI_76782 a rdfs:Class ; rdfs:label "EC 3.4.15.* (peptidyl-dipeptidase) inhibitor" ; rdfs:comment "Any EC 3.4.* (hydrolases acting on peptide bond) inhibitor that interferes with the activity of a peptidyl dipeptidase (EC 3.4.15.*)." ; rdfs:subClassOf obo:CHEBI_60258 . obo:NCBITaxon_384344 a rdfs:Class ; rdfs:label "Human coronavirus NO/0398/05" ; rdfs:subClassOf obo:NCBITaxon_384335 . obo:PR_Q15125 a rdfs:Class ; rdfs:label "3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase (human)" ; rdfs:comment "A 3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000006870 , obo:PR_000029067 . obo:PR_000012717 a rdfs:Class ; rdfs:label "phosphatidylinositol 3-kinase C2 domain-containing subunit gamma" ; rdfs:comment "A protein that is a translation product of the human PIK3C2G gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:CIDO_0020188 a rdfs:Class ; rdfs:label "Linea COVID-19 Assay Kit" ; rdfs:seeAlso ; rdfs:subClassOf obo:CIDO_0000454 . a rdfs:Class ; rdfs:label "Nervous System Activity Alteration [PE]" ; rdfs:subClassOf . obo:HP_0003075 a rdfs:Class ; rdfs:label "Hypoproteinemia" ; rdfs:comment "A decreased concentration of protein in the blood." ; rdfs:subClassOf obo:HP_0032180 . obo:CIDO_0000594 a rdfs:Class ; rdfs:label "AA variant in SARS-CoV-2 S protein S1 NTD region"@en ; rdfs:comment "An AA variant that is located in the RBD of SARS-CoV-2 S protein. In the original Wuhan strain, this contains amino acids from position 14-290." ; rdfs:subClassOf obo:CIDO_0000592 . obo:CHEBI_33582 a rdfs:Class ; rdfs:label "carbon group molecular entity" ; rdfs:subClassOf obo:CHEBI_33675 . obo:OPMI_0000493 a rdfs:Class ; rdfs:label "emergency room and inpatient visit"@en ; rdfs:comment "A vist ocurrence that includes a visit to the emergency room followed by a subsequent inpatient visit." ; rdfs:subClassOf obo:OPMI_0000482 . obo:OBI_0002543 a rdfs:Class ; rdfs:label "atrial appendage specimen" ; rdfs:comment "A specimen that is derived from the atrium auricular region." ; rdfs:subClassOf obo:OBI_0001479 . obo:CHEBI_33653 a rdfs:Class ; rdfs:label "aliphatic compound" ; rdfs:comment "Any acyclic or cyclic, saturated or unsaturated carbon compound, excluding aromatic compounds." ; rdfs:subClassOf obo:CHEBI_50860 . obo:NCBITaxon_1415850 a rdfs:Class ; rdfs:label "Bat SARS-like coronavirus Rs4110" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:NCBITaxon_2509469 a rdfs:Class ; rdfs:label "Andecovirus" ; rdfs:subClassOf obo:NCBITaxon_1159901 . obo:GO_0006812 a rdfs:Class ; rdfs:label "cation transport" ; rdfs:comment "The directed movement of cations, atoms or small molecules with a net positive charge, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." ; rdfs:subClassOf obo:GO_0006811 . obo:NCBITaxon_749433 a rdfs:Class ; rdfs:label "Pintail coronavirus PBA-37" ; rdfs:subClassOf obo:NCBITaxon_749416 . obo:NCBITaxon_2727984 a rdfs:Class ; rdfs:label "unclassified Myotacovirus" ; rdfs:subClassOf obo:NCBITaxon_2509500 . obo:OBI_0002531 a rdfs:Class ; rdfs:label "cortex of kidney specimen" ; rdfs:comment "A specimen that is derived from cortex of kidney." ; rdfs:subClassOf obo:OBI_0001479 . obo:GO_0071073 a rdfs:Class ; rdfs:label "positive regulation of phospholipid biosynthetic process" ; rdfs:comment "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of phospholipids." ; rdfs:subClassOf obo:GO_0031328 , obo:GO_0046889 , obo:GO_0071071 , obo:GO_1903727 . obo:PR_000030251 a rdfs:Class ; rdfs:label "E3 ubiquitin-protein ligase MYCBP2" ; rdfs:comment "A protein that is a translation product of the human MYCBP2 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:CIDO_0001065 a rdfs:Class ; rdfs:label "SARS-CoV2 orf9c protein binding to human TMED5" ; rdfs:comment "SARS-CoV2 orf9c protein binding to human TMED5, as evidented by an affinity-purification mass spectrometry experiment" ; rdfs:subClassOf obo:CIDO_0000054 . obo:CHEBI_51061 a rdfs:Class ; rdfs:label "hormone receptor modulator" ; rdfs:comment "A drug that modulates the function of the endocrine glands, the biosynthesis of their secreted hormones, or the action of hormones upon their specific sites." ; rdfs:subClassOf obo:CHEBI_23888 , obo:CHEBI_90710 . obo:PR_O60760 a rdfs:Class ; rdfs:label "hematopoietic prostaglandin D synthase (human)" ; rdfs:comment "A glutathione-requiring prostaglandin D synthase that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000013420 , obo:PR_000029067 . obo:CIDO_0000475 a rdfs:Class ; rdfs:label "VGGLYEIQIPSEFTI" ; rdfs:comment "A coronavirus epitope that is part of some S protein from HCoV OC43 composed of the following amino acids VGGLYEIQIPSEFTI" ; rdfs:subClassOf obo:CIDO_0000452 . a rdfs:Class ; rdfs:label "Movement Disorders [Disease/Finding]" ; rdfs:subClassOf . obo:PR_000006276 a rdfs:Class ; rdfs:label "death-associated protein kinase 1" ; rdfs:comment "A death-associated protein kinase that is a translation product of the human DAPK1 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000029896 . obo:CIDO_0000154 a rdfs:Class ; rdfs:label "COVID-19 epidemic"@en ; rdfs:subClassOf obo:CIDO_0000153 . obo:GO_0010605 a rdfs:Class ; rdfs:label "negative regulation of macromolecule metabolic process" ; rdfs:comment "Any process that decreases the frequency, rate or extent of the chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass." ; rdfs:subClassOf obo:GO_0009892 , obo:GO_0060255 . obo:PR_P53350 a rdfs:Class ; rdfs:label "serine/threonine-protein kinase PLK1 (human)" ; rdfs:comment "A serine/threonine-protein kinase PLK1 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000012870 , obo:PR_000029067 . obo:CHEBI_9635 a rdfs:Class ; rdfs:label "toremifene" ; rdfs:subClassOf obo:CHEBI_32876 , obo:CHEBI_35618 , obo:CHEBI_36683 . obo:HP_0011689 a rdfs:Class ; rdfs:label "Supraventricular tachycardia with a concealed accessory connection" ; rdfs:comment "Supraventricular tachycardia with an accessory connection mediated pathway that is called concealed becasue it is not seen on the ECG during sinus rhythm." ; rdfs:subClassOf obo:HP_0011688 . obo:PR_Q8TD10 a rdfs:Class ; rdfs:label "mirror-image polydactyly gene 1 protein (human)" ; rdfs:comment "A mirror-image polydactyly gene 1 protein that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000010419 , obo:PR_000029067 . obo:GO_0046889 a rdfs:Class ; rdfs:label "positive regulation of lipid biosynthetic process" ; rdfs:comment "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of lipids." ; rdfs:subClassOf obo:GO_0009891 , obo:GO_0045834 , obo:GO_0046890 . obo:VO_0004994 a rdfs:Class ; rdfs:label "SCB-2019"@en ; rdfs:comment "A SARS-CoV-2 trimeric S protein subunit vaccine." ; rdfs:subClassOf obo:VO_0005202 . obo:OBI_0000895 a rdfs:Class ; rdfs:label "total RNA extract" ; rdfs:comment "A RNA extract that is the output of an extraction process in which total celluar and organelle RNA molecules are isolated from a specimen." ; rdfs:subClassOf obo:OBI_0000880 . obo:CIDO_0001136 a rdfs:Class ; rdfs:label "SARS-CoV2 orf8 protein binding to human TM2D3"@en ; rdfs:comment "SARS-CoV2 orf8 protein binding to human TM2D3, as evidented by an affinity-purification mass spectrometry experiment" ; rdfs:subClassOf obo:CIDO_0000051 . obo:NCBITaxon_2078576 a rdfs:Class ; rdfs:label "Falcon coronavirus UAE-HKU27" ; rdfs:subClassOf obo:NCBITaxon_2724161 . obo:CIDO_0000035 a rdfs:Class ; rdfs:label "COVID-19 diagnostic process by ELISA serological assay"@en ; rdfs:comment "A COVID-19 diagnostic process that uses an serological assay that tests the serum from the blood specimen by an Enzyme Linked Immunosorbent Assay (ELISA) screening test" ; rdfs:subClassOf obo:CIDO_0000018 . a rdfs:Class ; rdfs:label "Protein Kinase Inhibitors [MoA]" ; rdfs:subClassOf . obo:HP_0030875 a rdfs:Class ; rdfs:label "Abnormality of pulmonary circulation" ; rdfs:comment "A functional anomaly of that portion of the cardiosvascular system that carries deoxygenated blood from the heart to the lungs and returns oxygenated blood back to the heart." ; rdfs:subClassOf obo:HP_0002795 , obo:HP_0030163 . a rdfs:Class ; rdfs:label "Phenothiazines [Chemical/Ingredient]" ; rdfs:subClassOf , . obo:CIDO_0000114 a rdfs:Class ; rdfs:label "modulation of host response to MERS-CoV infection"@en ; rdfs:comment "A process that modulates host response to SARS-CoV viral infection" ; rdfs:subClassOf obo:CIDO_0000111 . obo:PR_000050467 a rdfs:Class ; rdfs:label "hemoglobin subunit" ; rdfs:comment "A protein that is a translation product of the human HBA1, HBA2, HBB, HBD, HBE1, HBG1, HBG2, HBM, HBQ1, or HBZ genes, 1:1 orthologs thereof, or semi-orthologs thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:PR_000001184 a rdfs:Class ; rdfs:label "alpha-1B adrenergic receptor" ; rdfs:comment "An alpha-1 adrenergic receptor that is a translation product of the human ADRA1B gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000001115 . obo:CIDO_0000096 a rdfs:Class ; rdfs:label "host response to MERS-CoV infection"@en ; rdfs:comment "A coronavirus-host interaction by which the host responds to MERS-CoV viral infection" ; rdfs:subClassOf obo:CIDO_0000087 . obo:OAE_0004577 a rdfs:Class ; rdfs:label "Level 2 TTS AE"@en ; rdfs:comment "A probable case of TTS" ; rdfs:subClassOf obo:OAE_0004540 . obo:NCBITaxon_305417 a rdfs:Class ; rdfs:label "SARS coronavirus C028" ; rdfs:subClassOf obo:NCBITaxon_694009 . obo:CHEBI_24676 a rdfs:Class ; rdfs:label "hydroxybenzoic acid" ; rdfs:comment "Any benzoic acid carrying one or more phenolic hydroxy groups on the benzene ring." ; rdfs:subClassOf obo:CHEBI_22723 , obo:CHEBI_33853 . obo:NCBITaxon_305411 a rdfs:Class ; rdfs:label "SARS coronavirus C013" ; rdfs:subClassOf obo:NCBITaxon_694009 . obo:OBI_0002502 a rdfs:Class ; rdfs:label "cerebrospinal fluid specimen" ; rdfs:comment "A specimen that is derived from cerbrospinal fluid." ; rdfs:subClassOf obo:OBI_2000009 . obo:GO_0007268 a rdfs:Class ; rdfs:label "chemical synaptic transmission" ; rdfs:comment "The vesicular release of classical neurotransmitter molecules from a presynapse, across a chemical synapse, the subsequent activation of neurotransmitter receptors at the postsynapse of a target cell (neuron, muscle, or secretory cell) and the effects of this activation on the postsynaptic membrane potential and ionic composition of the postsynaptic cytosol. This process encompasses both spontaneous and evoked release of neurotransmitter and all parts of synaptic vesicle exocytosis. Evoked transmission starts with the arrival of an action potential at the presynapse." ; rdfs:subClassOf obo:GO_0007267 . obo:VO_0000118 a rdfs:Class ; rdfs:label "microbial derivative vaccine adjuvant" ; rdfs:subClassOf obo:VO_0000580 . obo:GO_0007210 a rdfs:Class ; rdfs:label "serotonin receptor signaling pathway" ; rdfs:comment "The series of molecular signals generated as a consequence of a serotonin receptor binding to one of its physiological ligands." ; rdfs:subClassOf obo:GO_0007165 . obo:CHEBI_32827 a rdfs:Class ; rdfs:label "D-threoninate" ; rdfs:comment "The D-enantiomer of threoninate." ; rdfs:subClassOf obo:CHEBI_32832 . obo:NCBITaxon_627440 a rdfs:Class ; rdfs:label "SARS coronavirus ExoN1" ; rdfs:subClassOf obo:NCBITaxon_698398 . obo:GO_0009612 a rdfs:Class ; rdfs:label "response to mechanical stimulus" ; rdfs:comment "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a mechanical stimulus." ; rdfs:subClassOf obo:GO_0009605 , obo:GO_0009628 . a rdfs:Class ; rdfs:label "Pharyngeal Diseases [Disease/Finding]" ; rdfs:subClassOf , . obo:CHEBI_39430 a rdfs:Class ; rdfs:label "dioxolane" ; rdfs:subClassOf obo:CHEBI_25693 , obo:CHEBI_38104 . obo:OBI_0001010 a rdfs:Class ; rdfs:label "nucleic acid extract" ; rdfs:comment "An extract that is the output of an extraction process in which nucleic acid molecules are isolated from a specimen." ; rdfs:subClassOf obo:OBI_0000423 , obo:OBI_0000953 . obo:CHEBI_80128 a rdfs:Class ; rdfs:label "angiotensin (1-9)" ; rdfs:comment "A nine amino acid peptide which is formed when angiotensin converting enzyme 2 (ACE2) hydrolyzes the carboxy terminal leucine from angiotensin I. It is a anti-cardiac hypertrophy agent." ; rdfs:subClassOf obo:CHEBI_48433 . obo:NCBITaxon_1788420 a rdfs:Class ; rdfs:label "Bat coronavirus MfulBtCoV/3709" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:NCBITaxon_1928434 a rdfs:Class ; rdfs:label "Betacoronavirus sp." ; rdfs:subClassOf obo:NCBITaxon_696098 . obo:CHEBI_5126 a rdfs:Class ; rdfs:label "Fluphenazine hydrochloride" ; rdfs:subClassOf obo:CHEBI_38093 . obo:PR_000001816 a rdfs:Class ; rdfs:label "HGF/MSP receptor type tyrosine-protein kinase" ; rdfs:comment "A protein with core architecture consisting of a signal sequence, followed by a Sema domain (Pfam:PF01403), three IPT/TIG domains (Pfam:PF01833), a transmembrane region, and a Protein tyrosine kinase domain (Pfam:PF07714)." ; rdfs:subClassOf obo:PR_000000001 . obo:PR_000010326 a rdfs:Class ; rdfs:label "7SK snRNA methylphosphate capping enzyme" ; rdfs:comment "A protein that is a translation product of the human MEPCE gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:NCBITaxon_1679914 a rdfs:Class ; rdfs:label "Coronavirus RCoV/NSP63/Rha_pum/RSA/2008" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:NCBITaxon_249078 a rdfs:Class ; rdfs:label "SARS coronavirus HGZ8L2" ; rdfs:subClassOf obo:NCBITaxon_694009 . obo:CIDO_0020195 a rdfs:Class ; rdfs:label "Lyra Direct SARS-CoV-2 Assay" ; rdfs:seeAlso ; rdfs:subClassOf obo:CIDO_0000454 . obo:PR_Q16539 a rdfs:Class ; rdfs:label "mitogen-activated protein kinase 14 (human)" ; rdfs:comment "A mitogen-activated protein kinase 14 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000003107 , obo:PR_000029067 . a rdfs:Class ; rdfs:label "Graft vs Host Disease [Disease/Finding]" ; rdfs:subClassOf . obo:GO_0030001 a rdfs:Class ; rdfs:label "metal ion transport" ; rdfs:comment "The directed movement of metal ions, any metal ion with an electric charge, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." ; rdfs:subClassOf obo:GO_0006812 . obo:CIDO_0001162 a rdfs:Class ; rdfs:label "AA variant in SARS-CoV-2 S protein S2 CH region"@en ; rdfs:subClassOf obo:CIDO_0000595 . obo:GO_0045859 a rdfs:Class ; rdfs:label "regulation of protein kinase activity" ; rdfs:comment "Any process that modulates the frequency, rate or extent of protein kinase activity." ; rdfs:subClassOf obo:GO_0001932 , obo:GO_0043549 . obo:GO_0051234 a rdfs:Class ; rdfs:label "establishment of localization" ; rdfs:comment "Any process that localizes a substance or cellular component. This may occur via movement, tethering or selective degradation." ; rdfs:subClassOf obo:GO_0051179 . obo:OBI_0002779 a rdfs:Class ; rdfs:label "mid-turbinate nasal swab specimen" ; rdfs:comment "A specimen that is collected with a mid-turbinate nasal swab from the turbinate area of the nasal cavity." ; rdfs:subClassOf obo:OBI_0002599 . a rdfs:Class ; rdfs:label "Glucocorticoid Receptor Agonists [MoA]" ; rdfs:subClassOf . obo:CHEBI_15734 a rdfs:Class ; rdfs:label "primary alcohol" ; rdfs:comment "A primary alcohol is a compound in which a hydroxy group, -OH, is attached to a saturated carbon atom which has either three hydrogen atoms attached to it or only one other carbon atom and two hydrogen atoms attached to it." ; rdfs:subClassOf obo:CHEBI_30879 . obo:NCBITaxon_389165 a rdfs:Class ; rdfs:label "Bat coronavirus Shandong/977/2006" ; rdfs:subClassOf obo:NCBITaxon_366617 . obo:NCBITaxon_681863 a rdfs:Class ; rdfs:label "Kenya bat coronavirus BtKY17" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:CIDO_0000272 a rdfs:Class ; rdfs:label "SARS-CoV-2 clade GRY virus"@en ; rdfs:comment "A SARS-CoV-2 clade G variant virus that carries the combination of Spike D614G and Nucleocapsid RG203KR mutations." ; rdfs:subClassOf obo:CIDO_0000235 , obo:CIDO_0000371 . obo:CHEBI_33434 a rdfs:Class ; rdfs:label "elemental halogen" ; rdfs:subClassOf obo:CHEBI_33259 . obo:NCBITaxon_229103 a rdfs:Class ; rdfs:label "Chicken enteric coronavirus" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:CHEBI_37955 a rdfs:Class ; rdfs:label "H1-receptor antagonist" ; rdfs:comment "H1-receptor antagonists are the drugs that selectively bind to but do not activate histamine H1 receptors, thereby blocking the actions of endogenous histamine." ; rdfs:subClassOf obo:CHEBI_37956 . a rdfs:Class ; rdfs:label "Unconsciousness [Disease/Finding]" ; rdfs:subClassOf . obo:NCBITaxon_681879 a rdfs:Class ; rdfs:label "Kenya bat coronavirus BtKY35" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:CHEBI_32638 a rdfs:Class ; rdfs:label "D-methioninium" ; rdfs:comment "The D-enantiomer of methioninium." ; rdfs:subClassOf obo:CHEBI_32646 . obo:VO_0005138 a rdfs:Class ; rdfs:label "CRT-N SARS vaccine" ; rdfs:comment "A SARS DNA vaccine made from encoding calrectulin linked to a SARS-CoV N protein" ; rdfs:subClassOf obo:VO_0012183 . obo:CIDO_0000583 a rdfs:Class ; rdfs:label "SARS-CoV-2 Nsp9 protein interaction with host protein"@en ; rdfs:comment "A molecular interaction that has participant of the SARS-CoV-2 Nsp9 protein and a host protein" ; rdfs:subClassOf obo:CIDO_0000348 . obo:CIDO_0020183 a rdfs:Class ; rdfs:label "Laboratorio Clinico Toledo SARS-CoV-2 Assay" ; rdfs:seeAlso ; rdfs:subClassOf obo:CIDO_0000454 . obo:HP_0033121 a rdfs:Class ; rdfs:label "Barking cough" ; rdfs:comment "A cough with a characteristic sound that has been compared to a seal's bark." ; rdfs:subClassOf obo:HP_0012735 . obo:CHEBI_25634 a rdfs:Class ; rdfs:label "octadecenoic acid" ; rdfs:comment "Any member of the group of C18 monounsaturated fatty acids with the double bond located at any position in the chain." ; rdfs:subClassOf obo:CHEBI_15904 , obo:CHEBI_25413 , obo:CHEBI_53339 . a rdfs:Class ; rdfs:label "BAICALIN" ; rdfs:subClassOf . obo:PR_000021997 a rdfs:Class ; rdfs:label "TRK receptor" ; rdfs:comment "A protein that is a tyrosine kinase receptor that is activated by dimerization, resulting in autophosphorylation of intracellular tyrosine residues and triggering of the signal transduction cascade." ; rdfs:subClassOf obo:PR_000000001 . obo:NCBITaxon_231516 a rdfs:Class ; rdfs:label "SARS coronavirus SZ1" ; rdfs:subClassOf obo:NCBITaxon_694009 . obo:NCBITaxon_2776791 a rdfs:Class ; rdfs:label "Bat coronavirus 210/09 P" ; rdfs:subClassOf obo:NCBITaxon_1986197 . obo:NCBITaxon_1699328 a rdfs:Class ; rdfs:label "Myotis Bat Alphacoronavirus strain YNXY_18C" ; rdfs:subClassOf obo:NCBITaxon_366617 . obo:HP_0011841 a rdfs:Class ; rdfs:label "Ventricular flutter" ; rdfs:comment "A potentially lethal cardiac arrhythmia characterized by an extremely rapid, hemodynamically unstable ventricular tachycardia (150-300 beats/min) with a large oscillating sine-wave appearance." ; rdfs:subClassOf obo:HP_0004756 . obo:CIDO_0001125 a rdfs:Class ; rdfs:label "SARS-CoV2 orf8 protein binding to human OS9"@en ; rdfs:comment "SARS-CoV2 orf8 protein binding to human OS9, as evidented by an affinity-purification mass spectrometry experiment" ; rdfs:subClassOf obo:CIDO_0000051 . a rdfs:Class ; rdfs:label "Serotonin Activity Alteration [PE]" ; rdfs:subClassOf . obo:CHEBI_29337 a rdfs:Class ; rdfs:label "azanide" ; rdfs:subClassOf obo:CHEBI_35106 , obo:CHEBI_79389 . obo:PR_P62942 a rdfs:Class ; rdfs:label "peptidyl-prolyl cis-trans isomerase FKBP1A (human)" ; rdfs:comment "A peptidyl-prolyl cis-trans isomerase FKBP1A that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000007536 , obo:PR_000029067 . obo:CHEBI_64996 a rdfs:Class ; rdfs:label "EC 1.13.11.33 (arachidonate 15-lipoxygenase) inhibitor" ; rdfs:comment "A lipoxygenase inhibitor that interferes with the action of arachidonate 15-lipoxygenase (EC 1.13.11.33)." ; rdfs:subClassOf obo:CHEBI_35856 , obo:CHEBI_76837 . obo:CIDO_0000821 a rdfs:Class ; rdfs:label "SARS-CoV2 nsp12 protein binding to human ZC3H7A" ; rdfs:comment "SARS-CoV2 nsp12 protein binding to human ZC3H7A, as evidented by an affinity-purification mass spectrometry experiment" ; rdfs:subClassOf obo:CIDO_0000057 . obo:OBI_0302716 a rdfs:Class ; rdfs:label "pool of specimens"@en ; rdfs:comment "A pool of specimens is a mixture of a population of samples which have been gathered from one or more sample populations, obtained by the physical process of mixing individual specimens, e.g. mixing the DNA collected from the individual fish."@en ; rdfs:subClassOf obo:OBI_0000953 , obo:OBI_0100051 . obo:GO_0045184 a rdfs:Class ; rdfs:label "establishment of protein localization" ; rdfs:comment "The directed movement of a protein to a specific location." ; rdfs:subClassOf obo:GO_0008104 , obo:GO_0051234 . obo:PR_Q8IWJ2 a rdfs:Class ; rdfs:label "GRIP and coiled-coil domain-containing protein 2 (human)" ; rdfs:comment "A GRIP and coiled-coil domain-containing protein 2 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000007887 , obo:PR_000029067 . obo:CIDO_0000378 a rdfs:Class ; rdfs:label "SARS-CoV-2 Epsilon variant"@en ; rdfs:subClassOf obo:CIDO_0000234 , obo:CIDO_0000407 . obo:CHEBI_36860 a rdfs:Class ; rdfs:label "14-hydroxy steroid" ; rdfs:subClassOf obo:CHEBI_35350 . obo:PR_000002112 a rdfs:Class ; rdfs:label "vascular endothelial growth factor receptor 2" ; rdfs:comment "A vascular endothelial growth factor receptor that is a translation product of the human KDR gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000001971 . obo:GO_0005253 a rdfs:Class ; rdfs:label "anion channel activity" ; rdfs:comment "Enables the energy-independent passage of anions across a lipid bilayer down a concentration gradient." ; rdfs:subClassOf obo:GO_0005216 , obo:GO_0015103 . obo:GO_0009582 a rdfs:Class ; rdfs:label "detection of abiotic stimulus" ; rdfs:comment "The series of events in which an (non-living) abiotic stimulus is received by a cell and converted into a molecular signal." ; rdfs:subClassOf obo:GO_0009628 , obo:GO_0051606 . obo:CHEBI_27570 a rdfs:Class ; rdfs:label "histidine" ; rdfs:comment "An alpha-amino acid that is propanoic acid bearing an amino substituent at position 2 and a 1H-imidazol-4-yl group at position 3." ; rdfs:subClassOf obo:CHEBI_24780 , obo:CHEBI_26167 , obo:CHEBI_33704 , obo:CHEBI_33856 . obo:CHEBI_50906 a rdfs:Class ; rdfs:label "role" ; rdfs:comment "A role is particular behaviour which a material entity may exhibit." ; rdfs:subClassOf obo:BFO_0000017 . obo:PR_000010151 a rdfs:Class ; rdfs:label "mitogen-activated protein kinase 10" ; rdfs:comment "A protein that is a translation product of the human MAPK10 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:NCBITaxon_864619 a rdfs:Class ; rdfs:label "Bat coronavirus NM98-62/GER/2008" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:CIDO_0020194 a rdfs:Class ; rdfs:label "LYHER Novel Coronavirus (2019-nCoV) IgM/IgG Antibody Combo Test Kit (Colloidal Gold)" ; rdfs:seeAlso ; rdfs:subClassOf obo:CIDO_0000454 . obo:PR_000015756 a rdfs:Class ; rdfs:label "STE20/SPS1-related proline-alanine-rich protein kinase" ; rdfs:comment "A protein that is a translation product of the human STK39 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:CIDO_0020133 a rdfs:Class ; rdfs:label "EURORealTime SARS-CoV-2" ; rdfs:seeAlso ; rdfs:subClassOf obo:CIDO_0000454 . obo:OBI_0666666 a rdfs:Class ; rdfs:label "RNA extraction"@en ; rdfs:comment "A RNA extraction is a nucleic acid extraction where the desired output material is RNA"@en ; rdfs:subClassOf obo:OBI_0666667 . obo:GO_0019226 a rdfs:Class ; rdfs:label "transmission of nerve impulse" ; rdfs:comment "The neurological system process in which a signal is transmitted through the nervous system by a combination of action potential propagation and synaptic transmission." ; rdfs:subClassOf obo:GO_0035637 , obo:GO_0050877 . obo:CIDO_0000559 a rdfs:Class ; rdfs:label "TIFNCVYALNNVYLG" ; rdfs:comment "A coronavirus epitope that is part of some S protein from HCoV OC43 composed of the following amino acids TIFNCVYALNNVYLG" ; rdfs:subClassOf obo:CIDO_0000452 . obo:CIDO_0020174 a rdfs:Class ; rdfs:label "Inform Diagnostics SARS-CoV-2 RT-PCR Assay" ; rdfs:seeAlso ; rdfs:subClassOf obo:CIDO_0000454 . obo:CIDO_0000103 a rdfs:Class ; rdfs:label "interruption to coronavirus replication in host cell"@en ; rdfs:comment "A process that interrupts coronavirus entry to host cell" ; rdfs:subClassOf obo:CIDO_0000098 . obo:NCBITaxon_260550 a rdfs:Class ; rdfs:label "SARS coronavirus CUHK-L2" ; rdfs:subClassOf obo:NCBITaxon_694009 . obo:PR_000016374 a rdfs:Class ; rdfs:label "transducin-like enhancer protein 3" ; rdfs:comment "A protein that is a translation product of the human TLE3 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:CIDO_0000183 a rdfs:Class ; rdfs:label "COVID-19 Convalescent Plasma"@en ; rdfs:subClassOf obo:CIDO_0000172 . obo:NCBITaxon_1269326 a rdfs:Class ; rdfs:label "Betacoronavirus BtCoV/KW2E-F82/Nyc_spec/GHA/2011" ; rdfs:subClassOf obo:NCBITaxon_696098 . obo:PR_000010114 a rdfs:Class ; rdfs:label "amine oxidase [flavin-containing] A" ; rdfs:comment "A protein that is a translation product of the human MAOA gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:CHEBI_22918 a rdfs:Class ; rdfs:label "branched-chain amino acid" ; rdfs:comment "Any amino acid in which the parent hydrocarbon chain has one or more alkyl substituents" ; rdfs:subClassOf obo:CHEBI_33709 . obo:GO_0071869 a rdfs:Class ; rdfs:label "response to catecholamine" ; rdfs:comment "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a catecholamine stimulus. A catecholamine is any of a group of biogenic amines that includes 4-(2-aminoethyl)pyrocatechol [4-(2-aminoethyl)benzene-1,2-diol] and derivatives formed by substitution." ; rdfs:subClassOf obo:GO_0014070 , obo:GO_0071867 , obo:GO_1901700 . obo:PR_Q96NX5 a rdfs:Class ; rdfs:label "calcium/calmodulin-dependent protein kinase type 1G (human)" ; rdfs:comment "A calcium/calmodulin-dependent protein kinase type 1G that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000004990 , obo:PR_000029067 . obo:GO_0051336 a rdfs:Class ; rdfs:label "regulation of hydrolase activity" ; rdfs:comment "Any process that modulates the frequency, rate or extent of hydrolase activity, the catalysis of the hydrolysis of various bonds, e.g. C-O, C-N, C-C, phosphoric anhydride bonds, etc. Hydrolase is the systematic name for any enzyme of EC class 3." ; rdfs:subClassOf obo:GO_0050790 . obo:NCBITaxon_2042542 a rdfs:Class ; rdfs:label "Coronavirus PREDICT CoV-15" ; rdfs:subClassOf obo:NCBITaxon_366617 . obo:HP_0100776 a rdfs:Class ; rdfs:label "Recurrent pharyngitis" ; rdfs:comment "An increased susceptibility to pharyngitis as manifested by a history of recurrent pharyngitis." ; rdfs:subClassOf obo:HP_0002788 , obo:HP_0025439 . a rdfs:Class ; rdfs:label "Pregnadienetriols [Chemical/Ingredient]" ; rdfs:subClassOf . obo:OBI_0000552 a rdfs:Class ; rdfs:label "reverse transcribed polymerase chain reaction" ; rdfs:comment "reverse transcribe pcr is a process which allow amplification of cDNA during a pcr reaction while the cDNA results from a retrotranscription of messenger RNA isolated from a material entity." ; rdfs:subClassOf obo:OBI_0600058 . obo:CIDO_0001099 a rdfs:Class ; rdfs:label "SARS-CoV2 orf8 protein binding to human NEU1"@en ; rdfs:comment "SARS-CoV2 orf8 protein binding to human NEU1, as evidented by an affinity-purification mass spectrometry experiment" ; rdfs:subClassOf obo:CIDO_0000051 . obo:NCBITaxon_398810 a rdfs:Class ; rdfs:label "TGEV Miller M60" ; rdfs:subClassOf obo:NCBITaxon_33737 . a rdfs:Class ; rdfs:label "Female Urogenital Diseases and Pregnancy Complications [Disease/Finding]" ; rdfs:subClassOf . obo:CIDO_0000261 a rdfs:Class ; rdfs:label "COVID-19 LAMP diagnostic assay"@en ; rdfs:comment "A COVID-19 nucleic acid diagnostic assay that detects SARS-CoV-2 by loop mediated isothermal amplification (LAMP) assay" ; rdfs:subClassOf obo:CIDO_0000259 . obo:NCBITaxon_249067 a rdfs:Class ; rdfs:label "SARS coronavirus HGZ8L1-B" ; rdfs:subClassOf obo:NCBITaxon_694009 . obo:NCBITaxon_384347 a rdfs:Class ; rdfs:label "Human coronavirus NO/2708/04" ; rdfs:subClassOf obo:NCBITaxon_384335 . obo:CHEBI_76775 a rdfs:Class ; rdfs:label "EC 3.1.3.* (phosphoric monoester hydrolase) inhibitor" ; rdfs:comment "An EC 3.1.* (ester hydrolase) inhibitor that interferes with the action of any phosphoric monoester hydrolase (EC 3.1.3.*)." ; rdfs:subClassOf obo:CHEBI_76760 . obo:ENVO_01000797 a rdfs:Class ; rdfs:label "gaseous environmental material"@en ; rdfs:comment "A material entity which is composed of one or more chemical entities and has neither independent shape nor volume but tends to expand indefinitely." ; rdfs:subClassOf obo:ENVO_00010483 , obo:ENVO_02000140 . a rdfs:Class ; rdfs:label "BENZTROPINE MESYLATE" ; rdfs:subClassOf . a rdfs:Class ; rdfs:label "Dopamine Antagonists [MoA]" ; rdfs:subClassOf . obo:CIDO_0020213 a rdfs:Class ; rdfs:label "New York SARS-CoV-2 Real-time Reverse Transcriptase (RT)-PCR Diagnostic Panel" ; rdfs:seeAlso ; rdfs:subClassOf obo:CIDO_0000454 . obo:GO_0071363 a rdfs:Class ; rdfs:label "cellular response to growth factor stimulus" ; rdfs:comment "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a growth factor stimulus." ; rdfs:subClassOf obo:GO_0070848 , obo:GO_0071310 . obo:CHEBI_189649 a rdfs:Class ; rdfs:label "AC-55541" ; rdfs:subClassOf obo:CHEBI_50860 . a rdfs:Class ; rdfs:label "Decreased Immunologically Active Molecule Production [PE]" ; rdfs:subClassOf , . obo:GO_0044237 a rdfs:Class ; rdfs:label "cellular metabolic process" ; rdfs:comment "The chemical reactions and pathways by which individual cells transform chemical substances." ; rdfs:subClassOf obo:GO_0008152 , obo:GO_0009987 . obo:NCBITaxon_742005 a rdfs:Class ; rdfs:label "Bat SARS coronavirus HKU3-8" ; rdfs:subClassOf obo:NCBITaxon_442736 . obo:PR_000016850 a rdfs:Class ; rdfs:label "tyrosine-protein kinase TXK" ; rdfs:comment "A proto-oncogene SRC-like tyrosine-protein kinase that is a translation product of the human TXK gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000002997 . obo:NCBITaxon_1965089 a rdfs:Class ; rdfs:label "Coronavirus HKU15" ; rdfs:subClassOf obo:NCBITaxon_2509474 . obo:NCBITaxon_2487700 a rdfs:Class ; rdfs:label "Coronavirus SarBatCoV1" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:CIDO_0020309 a rdfs:Class ; rdfs:label "Triplex CII-CoV-1 rRT-PCR Test" ; rdfs:seeAlso ; rdfs:subClassOf obo:CIDO_0000454 . a rdfs:Class ; rdfs:label "Hemoglobinopathies [Disease/Finding]" ; rdfs:subClassOf , . a rdfs:Class ; rdfs:label "TOREMIFENE CITRATE" ; rdfs:subClassOf . obo:PR_P68400 a rdfs:Class ; rdfs:label "casein kinase II subunit alpha (human)" ; rdfs:comment "A casein kinase II subunit alpha that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000005950 , obo:PR_000029067 . obo:CIDO_0020021 a rdfs:Class ; rdfs:label "Altru Dx SARS-CoV-2 RT-PCR assay" ; rdfs:seeAlso ; rdfs:subClassOf obo:CIDO_0000454 . obo:PR_000015328 a rdfs:Class ; rdfs:label "smad nuclear-interacting protein 1" ; rdfs:comment "A protein that is a translation product of the human SNIP1 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . a rdfs:Class ; rdfs:label "Imidazoles [Chemical/Ingredient]" ; rdfs:subClassOf . obo:PR_Q9NYL2 a rdfs:Class ; rdfs:label "mitogen-activated protein kinase kinase kinase 20 (human)" ; rdfs:comment "A mitogen-activated protein kinase kinase kinase 20 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000010457 , obo:PR_000029067 . obo:NCBITaxon_1699347 a rdfs:Class ; rdfs:label "Myotis Bat Alphacoronavirus strain YNXY_7C" ; rdfs:subClassOf obo:NCBITaxon_366617 . obo:NCBITaxon_1788483 a rdfs:Class ; rdfs:label "Miniopterus bat coronavirus BtCov/3710" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:NCBITaxon_69075 a rdfs:Class ; rdfs:label "Rattus losea" ; rdfs:subClassOf obo:NCBITaxon_10114 . obo:OBI_0600058 a rdfs:Class ; rdfs:label "enzymatic amplification"@en ; rdfs:comment "the use of enzymes to increase the number of molecules of a biomaterial"@en ; rdfs:subClassOf obo:OBI_0000094 . obo:CHEBI_76735 a rdfs:Class ; rdfs:label "EC 1.8.* (oxidoreductase acting on sulfur group of donors) inhibitor" ; rdfs:comment "An oxidoreductase inhibitor which interferes with the action of an oxidoreductase of class EC 1.8.*.* (acting on a sulfur group of donors)." ; rdfs:subClassOf obo:CHEBI_76725 . obo:CHEBI_18310 a rdfs:Class ; rdfs:label "alkane" ; rdfs:comment "An acyclic branched or unbranched hydrocarbon having the general formula CnH2n+2, and therefore consisting entirely of hydrogen atoms and saturated carbon atoms." ; rdfs:subClassOf obo:CHEBI_24632 , obo:CHEBI_33653 . obo:CIDO_0000414 a rdfs:Class ; rdfs:label "susceptibility to up-regulation in COVID-19 female patient"@en ; rdfs:comment "A disposition that a material entity such as a gene or protein is susceptible to be up-regulated in COVID-19 female patient" ; rdfs:subClassOf obo:CIDO_0000413 . obo:RO_0000092 a rdf:Property ; rdfs:label "disposition of"@en ; rdfs:comment "inverse of has disposition" ; rdfs:range . obo:CHEBI_48422 a rdfs:Class ; rdfs:label "angiogenesis inhibitor" ; rdfs:comment "An agent and endogenous substances that antagonize or inhibit the development of new blood vessels." ; rdfs:subClassOf obo:CHEBI_23888 . a rdfs:Class ; rdfs:label "Decreased Central Nervous System Organized Electrical Activity [PE]" ; rdfs:subClassOf . obo:NCBITaxon_389160 a rdfs:Class ; rdfs:label "Bat coronavirus Anhui/911/2005" ; rdfs:subClassOf obo:NCBITaxon_366617 . obo:CIDO_0000955 a rdfs:Class ; rdfs:label "SARS-CoV2 nsp9 protein binding to human NEK9" ; rdfs:comment "SARS-CoV2 nsp9 protein binding to human NEK9, as evidented by an affinity-purification mass spectrometry experiment" ; rdfs:subClassOf obo:CIDO_0000583 . obo:PR_000044455 a rdfs:Class ; rdfs:label "lentivirus-type gag-pol polyprotein" ; rdfs:comment "A chimeric protein that is a translation product of a ribosomal frameshift between the human immunodeficiency virus type 1 group M subtype B (isolate HXB2) gag and pol genes, or 1:1 orthologs thereof." ; rdfs:subClassOf obo:PR_000003507 . a rdfs:Class ; rdfs:label "Lymphoma [Disease/Finding]" ; rdfs:subClassOf , . obo:NCBITaxon_903601 a rdfs:Class ; rdfs:label "Kenya bat coronavirus BtKY63" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:OGMS_0000097 a rdfs:Class ; rdfs:label "health care encounter" ; rdfs:subClassOf obo:OBI_0000011 . obo:CIDO_0000817 a rdfs:Class ; rdfs:label "SARS-CoV2 nsp12 protein binding to human TYSND1" ; rdfs:comment "SARS-CoV2 nsp12 protein binding to human TYSND1, as evidented by an affinity-purification mass spectrometry experiment" ; rdfs:subClassOf obo:CIDO_0000057 . obo:GO_0004930 a rdfs:Class ; rdfs:label "G protein-coupled receptor activity" ; rdfs:comment "Combining with an extracellular signal and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex." ; rdfs:subClassOf obo:GO_0003674 . obo:PR_000008757 a rdfs:Class ; rdfs:label "heparan sulfate 2-O-sulfotransferase 1" ; rdfs:comment "A protein that is a translation product of the human HS2ST1 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:OPMI_0000482 a rdfs:Class ; rdfs:label "visit occurrence"@en ; rdfs:comment "A process event where a person engages with the healthcare system for a duration of time. This includes inpatient or outpatient visit." ; rdfs:subClassOf obo:BFO_0000015 . obo:CIDO_0000049 a rdfs:Class ; rdfs:label "SARS-CoV-2 Nsp7 protein interaction with host protein"@en ; rdfs:comment "A molecular interaction that has participant of the SARS-CoV-2 Nsp7 protein and a host protein" ; rdfs:subClassOf obo:CIDO_0000348 . a rdfs:Class ; rdfs:label "Protein Synthesis Inhibitors [MoA]" ; rdfs:subClassOf . obo:APOLLO_SV_00000294 a rdfs:Class ; rdfs:label "agent-based disease transmission model"@en ; rdfs:subClassOf obo:APOLLO_SV_00000174 . obo:UBERON_0010314 a rdfs:Class ; rdfs:label "structure with developmental contribution from neural crest" ; rdfs:comment "An anatomical structure that has some part that develops from the neural crest." ; rdfs:subClassOf obo:UBERON_0000061 . obo:PR_Q9BYF1 a rdfs:Class ; rdfs:label "angiotensin-converting enzyme 2 (human)" ; rdfs:comment "An angiotensin-converting enzyme 2 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000003622 , obo:PR_000029067 . obo:NCBITaxon_235410 a rdfs:Class ; rdfs:label "SARS coronavirus Sin2774" ; rdfs:subClassOf obo:NCBITaxon_694009 . obo:CIDO_0001083 a rdfs:Class ; rdfs:label "AA variant in SARS-CoV-2 nsp12 protein"@en ; rdfs:subClassOf obo:CIDO_0000715 . obo:DRON_00723854 a rdfs:Class ; rdfs:label "function-inhibiting cytochrome P450 2D6 (CYP2D6) binding disposition" ; rdfs:subClassOf obo:BFO_0000016 . obo:DRON_00016915 a rdfs:Class ; rdfs:label "Interferon Alfa-2a" ; rdfs:subClassOf obo:OBI_0000047 . obo:CHEBI_47003 a rdfs:Class ; rdfs:label "leucine derivative" ; rdfs:comment "An amino acid derivative resulting from reaction of leucine at the amino group or the carboxy group, or from the replacement of any hydrogen of leucine by a heteroatom. The definition normally excludes peptides containing leucine residues." ; rdfs:subClassOf obo:CHEBI_83821 . obo:PR_000001094 a rdfs:Class ; rdfs:label "rhodopsin-like G-protein coupled receptor" ; rdfs:comment "A G-protein coupled receptor that contains the 7 transmembrane receptor (rhodopsin family) domain (Pfam:PF00001), which includes 7 transmembrane helices (TMI-TM7) with 3 intracellular loops (IL1-IL3) and 3 extracellular loops (EL1-EL3) between the helices. The amino-terminal region is extracellular and the carboxyl-terminal region is intracellular. Rhodopsin-like G-protein coupled receptors (GPCRs) are unique among the several classes of GPCRs in that most have a very short amino-terminal segment and several characteristic sequence motifs, particularly NSxxNPxxY in TM7 and D/E-R-Y/F between TM3 and loop IL2. Most bind their ligands within a cavity between the TM regions." ; rdfs:subClassOf obo:PR_000030035 . obo:CHEBI_30879 a rdfs:Class ; rdfs:label "alcohol" ; rdfs:comment "A compound in which a hydroxy group, -OH, is attached to a saturated carbon atom." ; rdfs:subClassOf obo:CHEBI_33822 . obo:CHEBI_60644 a rdfs:Class ; rdfs:label "bridged diphenyl antifungal agent" ; rdfs:comment "Any organic aromatic compound containing two phenyl (or substituted phenyl) groups attached to a single carbon or heteroatom and which has significant antifungal properties." ; rdfs:subClassOf obo:CHEBI_33659 . obo:PR_P10145 a rdfs:Class ; rdfs:label "interleukin-8 (human)" ; rdfs:comment "An interleukin-8 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000001395 , obo:PR_000029067 . obo:PR_000015054 a rdfs:Class ; rdfs:label "equilibrative nucleoside transporter 1" ; rdfs:comment "A protein that is a translation product of the human SLC29A1 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:VO_0005116 a rdfs:Class ; rdfs:label "Ad5.MERS-S1 vaccine" ; rdfs:comment "A MERS recombinant vector vaccine made of a recombinant adenoviral vector encoding the the S1 extracellular domain of S protein" ; rdfs:subClassOf obo:VO_0004900 . obo:PATO_0000125 a rdfs:Class ; rdfs:label "mass" ; rdfs:comment "A physical quality that inheres in a bearer by virtue of the proportion of the bearer's amount of matter." ; rdfs:subClassOf obo:BFO_0000019 . obo:CHEBI_63962 a rdfs:Class ; rdfs:label "Hsp90 inhibitor" ; rdfs:comment "An EC 3.6.4.10 (non-chaperonin molecular chaperone ATPase) inhibitor that blocks the action of heat shock protein 90." ; rdfs:subClassOf obo:CHEBI_76939 . obo:NCBITaxon_231421 a rdfs:Class ; rdfs:label "Bovine coronavirus strain OK" ; rdfs:subClassOf obo:NCBITaxon_11128 . obo:PR_P21430 a rdfs:Class ; rdfs:label "matrix protein 2 (Influenza A virus (strain A/Ann Arbor/6/1960 H2N2))" ; rdfs:comment "An influenzavirus matrix protein 2 that is encoded in the genome of the H2N2 strain A/Ann Arbor/6/1960." ; rdfs:subClassOf obo:PR_000036197 , obo:PR_000049764 . obo:CIDO_0000572 a rdfs:Class ; rdfs:label "TTQQAGAGIKYFCGM" ; rdfs:comment "A coronavirus epitope that is part of some S protein from HCoV 229E composed of the following amino acids TTQQAGAGIKYFCGM" ; rdfs:subClassOf obo:CIDO_0000451 . obo:VO_0004897 a rdfs:Class ; rdfs:label "coronavirus vaccine"@en ; rdfs:comment "A vaccine against coronavirus infection" ; rdfs:subClassOf obo:VO_0000609 . obo:DRON_00016762 a rdfs:Class ; rdfs:label "Phenazopyridine" ; rdfs:subClassOf obo:OBI_0000047 . a rdfs:Class ; rdfs:label "Tyrosine Kinase Inhibitors [MoA]" ; rdfs:subClassOf . obo:CHEBI_16523 a rdfs:Class ; rdfs:label "D-serine" ; rdfs:comment "The R-enantiomer of serine." ; rdfs:subClassOf obo:CHEBI_16733 , obo:CHEBI_17822 . obo:OBI_0002603 a rdfs:Class ; rdfs:label "areolar swab specimen" ; rdfs:comment "A specimen that is collected with a swab from the surface of an areola of a breast." ; rdfs:subClassOf obo:OBI_0002599 . obo:CHEBI_108226 a rdfs:Class ; rdfs:label "1,3-dimethyl-8-(4-phenyl-1-piperazinyl)-7H-purine-2,6-dione" ; rdfs:subClassOf obo:CHEBI_26144 . obo:CHEBI_33579 a rdfs:Class ; rdfs:label "main group molecular entity" ; rdfs:comment "A molecular entity containing one or more atoms from any of groups 1, 2, 13, 14, 15, 16, 17, and 18 of the periodic table." ; rdfs:subClassOf obo:CHEBI_23367 . a rdfs:Class ; rdfs:label "Pregnenediones [Chemical/Ingredient]" ; rdfs:subClassOf . a rdfs:Class ; rdfs:label "Monensin [Chemical/Ingredient]" ; rdfs:subClassOf . obo:BFO_0000003 a rdfs:Class ; rdfs:label "occurrent"@en ; rdfs:comment "An entity that has temporal parts and that happens, unfolds or develops through time."@en ; rdfs:subClassOf obo:BFO_0000001 . obo:PR_Q8IWR0 a rdfs:Class ; rdfs:label "zinc finger CCCH domain-containing protein 7A (human)" ; rdfs:comment "A zinc finger CCCH domain-containing protein 7A that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000029067 , obo:PR_000029880 . obo:NCBITaxon_231521 a rdfs:Class ; rdfs:label "SARS coronavirus HKU-66078" ; rdfs:subClassOf obo:NCBITaxon_694009 . a rdfs:Class ; rdfs:label "Triparanol [Chemical/Ingredient]" ; rdfs:subClassOf . obo:CHEBI_33250 a rdfs:Class ; rdfs:label "atom" ; rdfs:comment "A chemical entity constituting the smallest component of an element having the chemical properties of the element." ; rdfs:subClassOf obo:CHEBI_24431 . obo:GO_0080164 a rdfs:Class ; rdfs:label "regulation of nitric oxide metabolic process" ; rdfs:comment "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving nitric oxide, nitrogen monoxide (NO), a colorless gas only slightly soluble in water." ; rdfs:subClassOf obo:GO_0051171 . a rdfs:Class ; rdfs:label "TERCONAZOLE" ; rdfs:subClassOf . a rdfs:Class ; rdfs:label "Neoplasms, Experimental [Disease/Finding]" ; rdfs:subClassOf . obo:CHEBI_41609 a rdfs:Class ; rdfs:label "carbonate" ; rdfs:subClassOf obo:CHEBI_35604 . obo:GO_0005267 a rdfs:Class ; rdfs:label "potassium channel activity" ; rdfs:comment "Enables the facilitated diffusion of a potassium ion (by an energy-independent process) involving passage through a transmembrane aqueous pore or channel without evidence for a carrier-mediated mechanism." ; rdfs:subClassOf obo:GO_0005261 , obo:GO_0046873 . obo:CIDO_0000915 a rdfs:Class ; rdfs:label "SARS-CoV2 nsp7 protein binding to human RAB7A" ; rdfs:comment "SARS-CoV2 nsp7 protein binding to human RAB7A, as evidented by an affinity-purification mass spectrometry experiment" ; rdfs:subClassOf obo:CIDO_0000049 . a rdfs:Class ; rdfs:label "Endocrine Gland Neoplasms [Disease/Finding]" ; rdfs:subClassOf , . obo:CIDO_0001131 a rdfs:Class ; rdfs:label "SARS-CoV2 orf8 protein binding to human POFUT1"@en ; rdfs:comment "SARS-CoV2 orf8 protein binding to human POFUT1, as evidented by an affinity-purification mass spectrometry experiment" ; rdfs:subClassOf obo:CIDO_0000051 . obo:VO_0000495 a rdfs:Class ; rdfs:label "induction of adaptive immune response to antigen" ; rdfs:comment "induction of adaptive immune response to antigen is an active immunization process that results in induction of adaptive immune response to some antigens, for example, in a vaccine." ; rdfs:subClassOf obo:VO_0000491 . obo:CHEBI_24631 a rdfs:Class ; rdfs:label "hydrazines" ; rdfs:comment "Hydrazine (diazane) and its substituted derivatives." ; rdfs:subClassOf obo:CHEBI_51143 . obo:PR_000010002 a rdfs:Class ; rdfs:label "tyrosine-protein kinase Lyn" ; rdfs:comment "A proto-oncogene SRC-like tyrosine-protein kinase that is a translation product of the human LYN gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000002997 . obo:GO_0018130 a rdfs:Class ; rdfs:label "heterocycle biosynthetic process" ; rdfs:comment "The chemical reactions and pathways resulting in the formation of heterocyclic compounds, those with a cyclic molecular structure and at least two different atoms in the ring (or rings)." ; rdfs:subClassOf obo:GO_0044249 , obo:GO_0046483 . obo:OAE_0000085 a rdfs:Class ; rdfs:label "vascular disorder AE" ; rdfs:comment "a cardiovascular disorder AE that has a vascular disorder outcome" ; rdfs:subClassOf obo:OAE_0000493 . obo:CHEBI_30089 a rdfs:Class ; rdfs:label "acetate" ; rdfs:comment "A monocarboxylic acid anion resulting from the removal of a proton from the carboxy group of acetic acid." ; rdfs:subClassOf obo:CHEBI_35757 . obo:GO_0070588 a rdfs:Class ; rdfs:label "calcium ion transmembrane transport" ; rdfs:comment "A process in which a calcium ion is transported from one side of a membrane to the other by means of some agent such as a transporter or pore." ; rdfs:subClassOf obo:GO_0030001 , obo:GO_0098662 . obo:NCBITaxon_1269315 a rdfs:Class ; rdfs:label "Coronavirus BtCoV/KP565/Art_jam/PAN/2010" ; rdfs:subClassOf obo:NCBITaxon_2664420 . a rdfs:Class ; rdfs:label "Heterocyclic Compounds, Bridged-Ring [Chemical/Ingredient]" ; rdfs:subClassOf . obo:CHEBI_68478 a rdfs:Class ; rdfs:label "everolimus" ; rdfs:comment "A macrocyclic lactone that is rapamycin in which the hydroxy group attached to the cyclohexyl moiety has been converted into the corresponding 2-hydroxyethyl ether. It is an immunosuppressant and antineoplastic agent." ; rdfs:subClassOf obo:CHEBI_145565 , obo:CHEBI_15734 , obo:CHEBI_25698 , obo:CHEBI_35681 , obo:CHEBI_3992 , obo:CHEBI_59770 . obo:PR_Q8N0X7 a rdfs:Class ; rdfs:label "spartin (human)" ; rdfs:comment "A spartin that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000015518 , obo:PR_000029067 . obo:PR_000011125 a rdfs:Class ; rdfs:label "serine/threonine-protein kinase Nek1" ; rdfs:comment "A protein that is a translation product of the human NEK1 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:NCBITaxon_9611 a rdfs:Class ; rdfs:label "Canis" ; rdfs:subClassOf obo:NCBITaxon_9608 . obo:CHEBI_26872 a rdfs:Class ; rdfs:label "terpene ketone" ; rdfs:comment "Any terpenoid which contains a keto group." ; rdfs:subClassOf obo:CHEBI_17087 , obo:CHEBI_26873 . obo:CHEBI_33709 a rdfs:Class ; rdfs:label "amino acid" ; rdfs:comment "A carboxylic acid containing one or more amino groups." ; rdfs:subClassOf obo:CHEBI_33575 , obo:CHEBI_50047 . obo:OAE_0000590 a rdfs:Class ; rdfs:label "increased heart rate AE" ; rdfs:comment "an arrhythmia AE that has an outcome of greater than average resting heart beats per minute, usually measured by the number of times the heart ventricles contract per unit of time, usually per minute"@en ; rdfs:subClassOf obo:OAE_0000660 . obo:OBI_2000002 a rdfs:Class ; rdfs:label "cervical mucus specimen" ; rdfs:comment "A specimen that is derived from some cervical mucus " ; rdfs:subClassOf obo:OBI_2000009 . obo:NCBITaxon_454955 a rdfs:Class ; rdfs:label "Feline coronavirus UU7" ; rdfs:subClassOf obo:NCBITaxon_12663 . obo:NCBITaxon_160235 a rdfs:Class ; rdfs:label "Avian infectious bronchitis virus (strain Beaudette CK)" ; rdfs:subClassOf obo:NCBITaxon_11120 . obo:CHEBI_6801 a rdfs:Class ; rdfs:label "metformin" ; rdfs:comment "A member of the class of guanidines that is biguanide the carrying two methyl substituents at position 1." ; rdfs:subClassOf obo:CHEBI_24436 . obo:PR_P06241 a rdfs:Class ; rdfs:label "tyrosine-protein kinase Fyn (human)" ; rdfs:comment "A tyrosine-protein kinase Fyn that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000003003 , obo:PR_000029067 . obo:PR_000010194 a rdfs:Class ; rdfs:label "mannan-binding lectin serine protease 2" ; rdfs:comment "A protein that is a translation product of the human MASP2 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . a rdfs:Class ; rdfs:label "Carbohydrates [Chemical/Ingredient]" ; rdfs:subClassOf . obo:CIDO_0020199 a rdfs:Class ; rdfs:label "MatMaCorp COVID-19 2SF Test" ; rdfs:seeAlso ; rdfs:subClassOf obo:CIDO_0000454 . a rdfs:Class ; rdfs:label "Immunologically Active Molecule Activity Alteration [PE]" ; rdfs:subClassOf . obo:PR_000010643 a rdfs:Class ; rdfs:label "28S ribosomal protein S5, mitochondrial" ; rdfs:comment "A protein that is a translation product of the human MRPS5 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:NCBITaxon_1679880 a rdfs:Class ; rdfs:label "Coronavirus Hare_CoV/La08_96/Lep_gra/ESP/2008" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:CIDO_0001030 a rdfs:Class ; rdfs:label "Meplazumab" ; rdfs:subClassOf obo:CHEBI_23367 . obo:NCBITaxon_693997 a rdfs:Class ; rdfs:label "Alphacoronavirus 1" ; rdfs:subClassOf obo:NCBITaxon_2501931 , obo:NCBITaxon_2509514 . a rdfs:Class ; rdfs:label "Elimination [PK]" ; rdfs:subClassOf . obo:NCBITaxon_1004948 a rdfs:Class ; rdfs:label "Rocky Mountain bat coronavirus 61/2007/EF" ; rdfs:subClassOf obo:NCBITaxon_366617 . obo:CHEBI_180653 a rdfs:Class ; rdfs:label "molnupiravir" ; rdfs:comment "A nucleoside analogue that is N(4)-hydroxycytidine in which the 5'-hydroxy group is replaced by a (2-methylpropanoyl)oxy group. It is the prodrug of the active antiviral ribonucleoside analog N(4)-hydroxycytidine (EIDD-1931), has activity against a number of RNA viruses including SARS-CoV-2, MERS-CoV, and seasonal and pandemic influenza viruses. It is currently in phase III trials for the treatment of patients with COVID-19." ; rdfs:subClassOf obo:CHEBI_24983 , obo:CHEBI_35725 , obo:CHEBI_60783 . obo:PR_P42345 a rdfs:Class ; rdfs:label "serine/threonine-protein kinase mTOR (human)" ; rdfs:comment "A serine/threonine-protein kinase mTOR that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000003041 , obo:PR_000029067 . obo:GO_0019814 a rdfs:Class ; rdfs:label "immunoglobulin complex" ; rdfs:comment "A protein complex that in its canonical form is composed of two identical immunoglobulin heavy chains and two identical immunoglobulin light chains, held together by disulfide bonds and sometimes complexed with additional proteins. An immunoglobulin complex may be embedded in the plasma membrane or present in the extracellular space, in mucosal areas or other tissues, or circulating in the blood or lymph." ; rdfs:subClassOf obo:GO_0032991 . obo:NCBITaxon_1897077 a rdfs:Class ; rdfs:label "Bat coronavirus Myo.nig/117/BRA/2013" ; rdfs:subClassOf obo:NCBITaxon_366617 . obo:CHEBI_26649 a rdfs:Class ; rdfs:label "serine derivative" ; rdfs:comment "An amino acid derivative resulting from reaction of serine at the amino group or the carboxy group, or from the replacement of any hydrogen of serine by a heteroatom. The definition normally excludes peptides containing serine residues." ; rdfs:subClassOf obo:CHEBI_83821 . a rdfs:Class ; rdfs:label "Constipation [Disease/Finding]" ; rdfs:subClassOf . obo:NCBITaxon_1508222 a rdfs:Class ; rdfs:label "Longquan Aa mouse coronavirus" ; rdfs:subClassOf obo:NCBITaxon_2724078 . obo:PR_Q8TD19 a rdfs:Class ; rdfs:label "serine/threonine-protein kinase Nek9 (human)" ; rdfs:comment "A serine/threonine-protein kinase Nek9 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000011135 , obo:PR_000029067 . obo:PR_P28472 a rdfs:Class ; rdfs:label "gamma-aminobutyric acid receptor subunit beta-3 (human)" ; rdfs:comment "A gamma-aminobutyric acid receptor subunit beta-3 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000007774 , obo:PR_000029067 . obo:PR_000016050 a rdfs:Class ; rdfs:label "serine/threonine-protein kinase TAO3" ; rdfs:comment "A protein that is a translation product of the human TAOK3 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:PR_000014475 a rdfs:Class ; rdfs:label "serine/threonine-protein kinase SBK1" ; rdfs:comment "A protein that is a translation product of the human SBK1 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:NCBITaxon_681857 a rdfs:Class ; rdfs:label "Kenya bat coronavirus BtKY10" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:PR_000005731 a rdfs:Class ; rdfs:label "catechol O-methyltransferase" ; rdfs:comment "A protein that is a translation product of the human COMT gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:OGG_2002697049 a rdfs:Class ; rdfs:label "gene of severe acute respiratory syndrome coronavirus 2" ; rdfs:comment "A gene that is part of the genome of severe acute respiratory syndrome coronavirus 2" ; rdfs:subClassOf obo:OGG_0000000002 , obo:OGG_20000011118 . obo:CIDO_0000406 a rdfs:Class ; rdfs:label "SARS-CoV-2 based on PANGO lineages"@en ; rdfs:subClassOf obo:NCBITaxon_2697049 . obo:NCBITaxon_231432 a rdfs:Class ; rdfs:label "Bovine coronavirus (strain OK-0514-3)" ; rdfs:subClassOf obo:NCBITaxon_231421 . obo:APOLLO_SV_00000303 a rdfs:Class ; rdfs:label "compartmental disease transmission model"@en ; rdfs:subClassOf obo:APOLLO_SV_00000174 . obo:CHEBI_38511 a rdfs:Class ; rdfs:label "indolizidine alkaloid" ; rdfs:subClassOf obo:CHEBI_22315 , obo:CHEBI_38485 . obo:CHEBI_74337 a rdfs:Class ; rdfs:label "D-asparagine zwitterion" ; rdfs:comment "A D-alpha-amino acid zwitterion that is D-asparagine in which a proton has been transferred from the carboxy group to the amino group. It is the major species at pH 7.3." ; rdfs:subClassOf obo:CHEBI_59871 . obo:PR_000009406 a rdfs:Class ; rdfs:label "kallikrein-1" ; rdfs:comment "A trypsin that is a translation product of the human KLK1 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000027795 . obo:PR_000050267 a rdfs:Class ; rdfs:label "spike protein S1 (SARS-CoV-2)" ; rdfs:comment "A spike glycoprotein, signal peptide removed form (SARS-CoV-2) that has been processed by proteolytic cleavage to yield the N-terminal portion. UniProtKB:P0DTC2, 13-685." ; rdfs:subClassOf obo:PR_000050266 . obo:PR_Q9H228 a rdfs:Class ; rdfs:label "sphingosine 1-phosphate receptor 5 (human)" ; rdfs:comment "A sphingosine 1-phosphate receptor 5 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000001710 , obo:PR_000029067 . obo:NCBITaxon_9608 a rdfs:Class ; rdfs:label "Canidae" ; rdfs:subClassOf obo:NCBITaxon_379584 . obo:PR_000015748 a rdfs:Class ; rdfs:label "serine/threonine-protein kinase 32A" ; rdfs:comment "A protein that is a translation product of the human STK32A gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:NCBITaxon_1746088 a rdfs:Class ; rdfs:label "Bat coronavirus P.pyg/GER/9848/2014" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:CHEBI_35473 a rdfs:Class ; rdfs:label "tranquilizing drug" ; rdfs:comment "A traditional grouping of drugs said to have a soothing or calming effect on mood, thought or behaviour." ; rdfs:subClassOf obo:CHEBI_35471 , obo:CHEBI_35488 . obo:CHEBI_50994 a rdfs:Class ; rdfs:label "primary amino compound" ; rdfs:comment "A compound formally derived from ammonia by replacing one hydrogen atom by an organyl group." ; rdfs:subClassOf obo:CHEBI_50047 . obo:PR_O15392 a rdfs:Class ; rdfs:label "baculoviral IAP repeat-containing protein 5 (human)" ; rdfs:comment "A baculoviral IAP repeat-containing protein 5 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000004753 , obo:PR_000029067 . obo:PR_P02747 a rdfs:Class ; rdfs:label "complement C1q subcomponent subunit C (human)" ; rdfs:comment "A complement C1q subcomponent subunit C that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000004878 , obo:PR_000029067 . obo:PR_000050272 a rdfs:Class ; rdfs:label "papain-like proteinase nsp3 (SARS-CoV-2)" ; rdfs:comment "A rep gene proteolytic cleavage product (SARS-CoV-2) that is the central portion produced by the autocatalytic action of PL-PRO proteinase (nsp3) when it cleaves the precursor rep gene translation product (SARS-CoV-2) between residues 818-819 and 2763-2764." ; rdfs:subClassOf obo:PR_000050281 . a rdfs:Class ; rdfs:label "Benzatropine Methanesulfonate [Chemical/Ingredient]" ; rdfs:subClassOf . obo:PR_000001282 a rdfs:Class ; rdfs:label "ALK tyrosine kinase receptor" ; rdfs:comment "A protein that is a translation product of the human ALK gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:PR_Q8NEJ9 a rdfs:Class ; rdfs:label "neuroguidin (human)" ; rdfs:comment "A neuroguidin that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000011192 , obo:PR_000029067 . obo:CIDO_0000165 a rdfs:Class ; rdfs:label "infectious droplet"@en ; rdfs:comment "Respiratory repiratory aerosols that is > 5 um in diameter" ; rdfs:subClassOf obo:CIDO_0000164 . obo:CHEBI_38497 a rdfs:Class ; rdfs:label "respiratory-chain inhibitor" ; rdfs:subClassOf obo:CHEBI_38496 . obo:CIDO_0000552 a rdfs:Class ; rdfs:label "VMLQIQLTGILDGDY" ; rdfs:comment "A coronavirus epitope that is part of some S protein from HCoV 229E composed of the following amino acids VMLQIQLTGILDGDY" ; rdfs:subClassOf obo:CIDO_0000451 . obo:CHEBI_86323 a rdfs:Class ; rdfs:label "conazole antifungal agent" ; rdfs:comment "A compound that has a structure that is related to miconazole, contains an azole (imidazole or triazole) moiety, and has significant systemic antifungal properties. They inhibit cytochrome P450-dependent enzymes (particularly C14-demethylase) involved in the biosynthesis of ergosterol, which is required for fungal cell membrane structure and function." ; rdfs:subClassOf obo:CHEBI_68452 . obo:CIDO_0000283 a rdfs:Class ; rdfs:label "SARS-CoV-2 life cycle"@en ; rdfs:subClassOf obo:CIDO_0000282 . obo:CHEBI_189662 a rdfs:Class ; rdfs:label "XL413" ; rdfs:comment "A benzofuropyrimidine that is 3,4-dihydro[1]benzofuro[3,2-d]pyrimidine substituted by (2S)-pyrrolidin-2-yl, oxo and chloro groups at positions 2, 4, and 8, respectively. It is a potent ATP competitive inhibitor of Cdc7 kinase (IC50 = 3.4 nM) and exhibits anticancer properties." ; rdfs:subClassOf obo:CHEBI_189664 , obo:CHEBI_36683 , obo:CHEBI_38260 . obo:CIDO_0000990 a rdfs:Class ; rdfs:label "SARS-CoV2 orf8 protein binding to human CISD3" ; rdfs:comment "SARS-CoV2 orf8 protein binding to human CISD3, as evidented by an affinity-purification mass spectrometry experiment" ; rdfs:subClassOf obo:CIDO_0000051 . a rdfs:Class ; rdfs:label "Benzofurans [Chemical/Ingredient]" ; rdfs:subClassOf . obo:CIDO_0000486 a rdfs:Class ; rdfs:label "STVVEVKSAIVCASV" ; rdfs:comment "A coronavirus epitope that is part of some S protein from HCoV NL63 composed of the following amino acids STVVEVKSAIVCASV" ; rdfs:subClassOf obo:CIDO_0000449 . obo:VO_0005156 a rdfs:Class ; rdfs:label "CoV2 SAM" ; rdfs:comment "A SARS-CoV-2 RNA vaccine that has a lipid nanoparticle (LNP) platform and Spike protein antigen" ; rdfs:subClassOf obo:VO_0005198 . obo:NCBITaxon_1288697 a rdfs:Class ; rdfs:label "Bat coronavirus POA/2012/E05" ; rdfs:subClassOf obo:NCBITaxon_366617 . obo:VO_0005392 a rdfs:Class ; rdfs:label "ACM-001"@en ; rdfs:comment "A SARS-CoV-2 protein subunit vaccine manufactured by ACM Biolabs." ; rdfs:subClassOf obo:VO_0005202 , obo:VO_0005269 . obo:NCIT_C16564 a rdfs:Class ; rdfs:label "Ethnic Group" ; rdfs:comment "A social group characterized by a distinctive social and cultural tradition that is maintained from generation to generation. Members share a common history and origin and a sense of identification with the group. They have similar and distinctive features in their lifestyle habits and shared experiences. They often have a common genetic heritage which may be reflected in their experience of health and disease." ; rdfs:subClassOf obo:NCIT_C17005 . obo:PR_Q15904 a rdfs:Class ; rdfs:label "V-type proton ATPase subunit S1 (human)" ; rdfs:comment "A V-type proton ATPase subunit S1 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000004468 , obo:PR_000029067 . obo:CIDO_0020097 a rdfs:Class ; rdfs:label "COVID-19 RT-PCR Peptide Nucleic Acid (PNA) kit" ; rdfs:seeAlso ; rdfs:subClassOf obo:CIDO_0000454 . obo:VO_0005196 a rdfs:Class ; rdfs:label "VXA-CoV2-1"@en ; rdfs:comment "A SARS-CoV-2 adenoviral vector-based oral vaccine by Vaxart expressing a SARS-CoV-2 antigen and dsRNA adjuvant" ; rdfs:subClassOf obo:VO_0005200 . obo:CHEBI_23007 a rdfs:Class ; rdfs:label "carbohydrate-containing antibiotic" ; rdfs:comment "Any carbohydrate derivative that exhibits antibiotic activity." ; rdfs:subClassOf obo:CHEBI_63299 . obo:CIDO_0000839 a rdfs:Class ; rdfs:label "SARS-CoV2 nsp13 protein binding to human GCC2" ; rdfs:comment "SARS-CoV2 nsp13 protein binding to human GCC2, as evidented by an affinity-purification mass spectrometry experiment" ; rdfs:subClassOf obo:CIDO_0000058 . obo:VO_0005141 a rdfs:Class ; rdfs:label "CoronaVac" ; rdfs:comment "A SARS-CoV-2 whole virus vaccine made from a purified inactivated SARS-CoV-2 virus." ; rdfs:subClassOf obo:VO_0005266 . obo:PR_000013411 a rdfs:Class ; rdfs:label "polypyrimidine tract-binding protein 2" ; rdfs:comment "A protein that is a translation product of the human PTBP2 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:PATO_0001547 a rdfs:Class ; rdfs:label "quality of a gas" ; rdfs:comment "A physical quality inhering in a bearer by virtue of the bearer's exhibiting the physical characteristics of an entity consisting of particles that have neither a defined volume nor defined shape." ; rdfs:subClassOf obo:PATO_0002198 . obo:NCBITaxon_1415842 a rdfs:Class ; rdfs:label "Bat SARS-like coronavirus Rs4087-1" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:UBERON_0000362 a rdfs:Class ; rdfs:label "renal medulla" ; rdfs:comment "the inner portion of the kidney consisting of the renal pyramids" ; rdfs:subClassOf obo:UBERON_0000481 . obo:CIDO_0000767 a rdfs:Class ; rdfs:label "SARS-CoV2 M protein binding to human SAAL1" ; rdfs:comment "SARS-CoV2 M protein binding to human SAAL1, as evidented by an affinity-purification mass spectrometry experiment" ; rdfs:subClassOf obo:CIDO_0000055 . obo:NCBITaxon_511433 a rdfs:Class ; rdfs:label "SARS coronavirus BJ182b" ; rdfs:subClassOf obo:NCBITaxon_694009 . obo:NCBITaxon_681869 a rdfs:Class ; rdfs:label "Kenya bat coronavirus BtKY23" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:NCBITaxon_1964808 a rdfs:Class ; rdfs:label "Coronavirus JC30" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:VO_0005179 a rdfs:Class ; rdfs:label "lipid nanoparticle vector"@en ; rdfs:comment "A nanoparticle vector composed of lipids." ; rdfs:subClassOf obo:VO_0005180 . obo:CHEBI_62803 a rdfs:Class ; rdfs:label "fuel additive" ; rdfs:comment "Any additive that enhances the efficiency of fuel." ; rdfs:subClassOf obo:CHEBI_51086 . obo:CIDO_0020234 a rdfs:Class ; rdfs:label "PhoenixDx SARS-CoV-2 Multiplex" ; rdfs:seeAlso ; rdfs:subClassOf obo:CIDO_0000454 . obo:PR_P09769 a rdfs:Class ; rdfs:label "tyrosine-protein kinase Fgr (human)" ; rdfs:comment "A tyrosine-protein kinase Fgr that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000007510 , obo:PR_000029067 . a rdfs:Class ; rdfs:label "anidulafungin [Chemical/Ingredient]" ; rdfs:subClassOf . obo:CIDO_0000086 a rdfs:Class ; rdfs:label "coronavirus replication inside cell"@en ; rdfs:comment "A coronavirus-host interaction by which the virus replicates inside the host cell" ; rdfs:subClassOf obo:CIDO_0000198 , obo:CIDO_0000285 . obo:NCBITaxon_658930 a rdfs:Class ; rdfs:label "Infectious bronchitis virus NGA/A116E7/2006" ; rdfs:subClassOf obo:NCBITaxon_11120 . obo:UBERON_0007610 a rdfs:Class ; rdfs:label "tibial artery" ; rdfs:comment "The anterior and posterior arteries created at the bifurcation of the popliteal artery. The anterior tibial artery begins at the lower border of the popliteus muscle and lies along the tibia at the distal part of the leg to surface superficially anterior to the ankle joint. Its branches are distributed throughout the leg, ankle, and pes. The posterior tibial artery begins at the lower border of the popliteus muscle, lies behind the tibia in the lower part of its course, and is found situated between the medial malleolus and the medial process of the calcaneal tuberosity. Its branches are distributed throughout the leg and foot." ; rdfs:subClassOf obo:UBERON_0000465 . obo:NCBITaxon_1269304 a rdfs:Class ; rdfs:label "Coronavirus BtCoV/KCR253/Car_per/CRC/2010" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:PR_O15075 a rdfs:Class ; rdfs:label "serine/threonine-protein kinase DCLK1 (human)" ; rdfs:comment "A serine/threonine-protein kinase DCLK1 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000006310 , obo:PR_000029067 . obo:HP_0004763 a rdfs:Class ; rdfs:label "Paroxysmal supraventricular tachycardia" ; rdfs:comment "An episodic form of supraventricular tachycardia with abrupt onset and termination." ; rdfs:subClassOf obo:HP_0004755 . a rdfs:Class ; rdfs:label "Heterocyclic Compounds, 3-Ring [Chemical/Ingredient]" ; rdfs:subClassOf . obo:VO_0000484 a rdfs:Class ; rdfs:label "recombinant vector vaccine" ; rdfs:comment "A vaccine that uses a modified virus or bacterium to deliver genes that code for microbial antigens to cells of the body." ; rdfs:subClassOf obo:VO_0000001 . obo:CIDO_0001120 a rdfs:Class ; rdfs:label "SARS-CoV2 orf8 protein binding to human GGH"@en ; rdfs:comment "SARS-CoV2 orf8 protein binding to human GGH, as evidented by an affinity-purification mass spectrometry experiment" ; rdfs:subClassOf obo:CIDO_0000051 . obo:GO_0042310 a rdfs:Class ; rdfs:label "vasoconstriction" ; rdfs:comment "A decrease in the diameter of blood vessels, especially arteries, due to constriction of smooth muscle cells that line the vessels, and usually causing an increase in blood pressure." ; rdfs:subClassOf obo:GO_0097746 . obo:CHEBI_16991 a rdfs:Class ; rdfs:label "deoxyribonucleic acid" ; rdfs:comment "High molecular weight, linear polymers, composed of nucleotides containing deoxyribose and linked by phosphodiester bonds; DNA contain the genetic information of organisms." ; rdfs:subClassOf obo:CHEBI_33696 . obo:PR_Q86UT6 a rdfs:Class ; rdfs:label "NLR family member X1 (human)" ; rdfs:comment "An NLR family member X1 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000011278 , obo:PR_000029067 . obo:CHEBI_16313 a rdfs:Class ; rdfs:label "D-proline" ; rdfs:comment "The D-enantiomer of proline." ; rdfs:subClassOf obo:CHEBI_16733 , obo:CHEBI_26271 . a rdfs:Class ; rdfs:label "Interferons [Chemical/Ingredient]" ; rdfs:subClassOf . obo:UBERON_0003688 a rdfs:Class ; rdfs:label "omentum" ; rdfs:comment "A fold of peritoneum originating at the stomach and supporting the viscera." ; rdfs:subClassOf obo:UBERON_0000465 . obo:CIDO_0000006 a rdfs:Class ; rdfs:label "Human coronavirus OC43 disease process"@en ; rdfs:subClassOf obo:CIDO_0000001 . obo:CHEBI_8462 a rdfs:Class ; rdfs:label "promethazine hydrochloride" ; rdfs:comment "The hydrochloride salt of promethazine." ; rdfs:subClassOf obo:CHEBI_36807 . obo:NCBITaxon_384339 a rdfs:Class ; rdfs:label "Human coronavirus NO/0848/04" ; rdfs:subClassOf obo:NCBITaxon_384335 . obo:PR_000005207 a rdfs:Class ; rdfs:label "serine/threonine-protein kinase MRCK gamma" ; rdfs:comment "A protein that is a translation product of the human CDC42BPG gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:PR_Q9BVK2 a rdfs:Class ; rdfs:label "probable dolichyl pyrophosphate Glc1Man9GlcNAc2 alpha-1,3-glucosyltransferase (human)" ; rdfs:comment "A probable dolichyl pyrophosphate Glc1Man9GlcNAc2 alpha-1,3-glucosyltransferase that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000029067 , obo:PR_000031475 . obo:NCBITaxon_1699329 a rdfs:Class ; rdfs:label "Myotis Bat Alphacoronavirus strain YNXY_19C" ; rdfs:subClassOf obo:NCBITaxon_366617 . obo:CHEBI_48675 a rdfs:Class ; rdfs:label "antifibrinolytic drug" ; rdfs:comment "A drug that prevent fibrinolysis or lysis of a blood clot or thrombus." ; rdfs:subClassOf obo:CHEBI_48676 . obo:NCBITaxon_426763 a rdfs:Class ; rdfs:label "Coronavirus group 2c" ; rdfs:subClassOf obo:NCBITaxon_696098 . obo:CHEBI_48854 a rdfs:Class ; rdfs:label "sulfurous acid" ; rdfs:subClassOf obo:CHEBI_33402 . obo:PR_Q9UJC3 a rdfs:Class ; rdfs:label "protein Hook homolog 1 (human)" ; rdfs:comment "A protein Hook homolog 1 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000008682 , obo:PR_000029067 . obo:CIDO_0000786 a rdfs:Class ; rdfs:label "SARS-CoV2 N protein binding to human RBM28" ; rdfs:comment "SARS-CoV2 N protein binding to human RBM28, as evidented by an affinity-purification mass spectrometry experiment" ; rdfs:subClassOf obo:CIDO_0000056 . obo:PR_P54646 a rdfs:Class ; rdfs:label "5'-AMP-activated protein kinase catalytic subunit alpha-2 (human)" ; rdfs:comment "A 5'-AMP-activated protein kinase catalytic subunit alpha-2 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000013219 , obo:PR_000029067 . obo:CHEBI_52090 a rdfs:Class ; rdfs:label "methoxide" ; rdfs:comment "An organic anion that is the conjugate base of methanol." ; rdfs:subClassOf obo:CHEBI_25696 . obo:NCBITaxon_1503299 a rdfs:Class ; rdfs:label "BtRf-BetaCoV/JL2012" ; rdfs:subClassOf obo:NCBITaxon_694009 . obo:PR_P0DTC3 a rdfs:Class ; rdfs:label "ORF3a protein (SARS-CoV-2)" ; rdfs:comment "A protein that is a translation product of the ORF3a gene in SARS-CoV-2." ; rdfs:subClassOf obo:PR_000050262 . obo:CIDO_0020324 a rdfs:Class ; rdfs:label "ViroKey SARS-CoV-2 RT-PCR Test" ; rdfs:seeAlso ; rdfs:subClassOf obo:CIDO_0000454 . obo:NCBITaxon_33213 a rdfs:Class ; rdfs:label "Bilateria" ; rdfs:subClassOf obo:NCBITaxon_33154 , obo:NCBITaxon_6072 . a rdfs:Class ; rdfs:label "Ion Channel Interactions [MoA]" ; rdfs:subClassOf . a rdfs:Class ; rdfs:label "CHLOROQUINE PHOSPHATE" ; rdfs:subClassOf . obo:HP_0006510 a rdfs:Class ; rdfs:label "Chronic pulmonary obstruction" ; rdfs:comment "An anomaly that is characterized progressive airflow obstruction that is only partly reversible, inflammation in the airways, and systemic effects or comorbities." ; rdfs:subClassOf obo:HP_0002795 . obo:CIDO_0000494 a rdfs:Class ; rdfs:label "EFRDYFNNNTDSIVI" ; rdfs:comment "A coronavirus epitope that is part of some S protein from HCoV NL63 composed of the following amino acids EFRDYFNNNTDSIVI" ; rdfs:subClassOf obo:CIDO_0000449 . obo:CIDO_0000046 a rdfs:Class ; rdfs:label "SARS-CoV-2 E protein interaction with host protein"@en ; rdfs:comment "A molecular interaction that has participant of the SARS-CoV-2 E protein and a host protein" ; rdfs:subClassOf obo:CIDO_0000348 . obo:PR_000011082 a rdfs:Class ; rdfs:label "NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 2" ; rdfs:comment "A protein that is a translation product of the human NDUFAF2 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . a rdfs:Class ; rdfs:label "Sympathetic Activity Alteration [PE]" ; rdfs:subClassOf . obo:VO_0000287 a rdfs:Class ; rdfs:label "vaccine-induced host immune response" ; rdfs:comment "Any immune system process that functions in the calibrated response of the host to a vaccine." ; rdfs:subClassOf obo:VO_0000288 . obo:CIDO_0001045 a rdfs:Class ; rdfs:label "SARS-CoV2 orf9c protein binding to human ACAD9" ; rdfs:comment "SARS-CoV2 orf9c protein binding to human ACAD9, as evidented by an affinity-purification mass spectrometry experiment" ; rdfs:subClassOf obo:CIDO_0000054 . obo:PR_000007205 a rdfs:Class ; rdfs:label "estrogen receptor beta" ; rdfs:comment "A protein that is a translation product of the human ESR2 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:PR_P31151 a rdfs:Class ; rdfs:label "protein S100-A7 (human)" ; rdfs:comment "A protein S100-A7 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000014414 , obo:PR_000029067 . obo:CHEBI_24852 a rdfs:Class ; rdfs:label "insecticide" ; rdfs:comment "Strictly, a substance intended to kill members of the class Insecta. In common usage, any substance used for preventing, destroying, repelling or controlling insects." ; rdfs:subClassOf obo:CHEBI_25944 . obo:CIDO_0020241 a rdfs:Class ; rdfs:label "Pro-AmpRT SARS-CoV-2 Test" ; rdfs:seeAlso ; rdfs:subClassOf obo:CIDO_0000454 . obo:PR_000008149 a rdfs:Class ; rdfs:label "Golgi reassembly-stacking protein 1" ; rdfs:comment "A protein that is a translation product of the human GORASP1 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:CHEBI_77703 a rdfs:Class ; rdfs:label "EC 4.3.1.3 (histidine ammonia-lyase) inhibitor" ; rdfs:comment "An EC 4.3.1.* (ammonia-lyase) inhibitor that interferes with the action of histidine ammonia-lyase (EC 4.3.1.3)." ; rdfs:subClassOf obo:CHEBI_76832 . obo:NCBITaxon_931905 a rdfs:Class ; rdfs:label "Alphacoronavirus Eptesicus fuscus/Appalachian Ridge/P1-C348/IT/USA/2009" ; rdfs:subClassOf obo:NCBITaxon_366617 . obo:CHEBI_142348 a rdfs:Class ; rdfs:label "hexahydronaphthalenes" ; rdfs:comment "Any carbobycyclic compound that is an hexahydronaphthalene or a compound obtained from an hexahydronaphthalene by formal substitution of one or more hydrogens." ; rdfs:subClassOf obo:CHEBI_36785 . obo:CHEBI_18237 a rdfs:Class ; rdfs:label "glutamic acid" ; rdfs:comment "An alpha-amino acid that is glutaric acid bearing a single amino substituent at position 2." ; rdfs:subClassOf obo:CHEBI_26167 , obo:CHEBI_33704 . a rdfs:Class ; rdfs:label "6-Mercaptopurine [Chemical/Ingredient]" ; rdfs:subClassOf , . obo:DRON_00000060 a rdfs:Class ; rdfs:label "function-inhibiting glucocorticoid steroid receptor binding disposition"@en ; rdfs:comment "A disposition to bind to a glucocorticoid steroid receptor in such a way as to prevent the realization of the function of the receptor."@en ; rdfs:subClassOf obo:BFO_0000016 . obo:CHEBI_35820 a rdfs:Class ; rdfs:label "antiprotozoal drug" ; rdfs:comment "Any antimicrobial drug which is used to treat or prevent protozoal infections." ; rdfs:subClassOf obo:CHEBI_35442 , obo:CHEBI_36043 . obo:CHEBI_58048 a rdfs:Class ; rdfs:label "L-asparagine zwitterion" ; rdfs:comment "Zwitterionic form of L-asparagine arising from transfer of a proton from the carboxy to the amino group; major species at pH 7.3." ; rdfs:subClassOf obo:CHEBI_35238 . obo:PR_000004973 a rdfs:Class ; rdfs:label "calcitonin gene-related peptide type 1 receptor" ; rdfs:comment "A calcitonin receptor protein that is a translation product of the human CALCRL gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000044637 . obo:VO_0005320 a rdfs:Class ; rdfs:label "202-CoV"@en ; rdfs:comment "A SARS-CoV-2 subunit vaccine manufactured by Shanghai Zerun Biotechnology, Walvax Biotechnology, and CEPI" ; rdfs:subClassOf obo:VO_0005202 . obo:DOID_0070081 a rdfs:Class ; rdfs:label "schizophrenia 5" ; rdfs:comment "A schizophrenia that has_material_basis_in a mutation on chromosome 6q13-q26." ; rdfs:subClassOf obo:DOID_0050736 , obo:DOID_5419 . obo:NCBITaxon_996626 a rdfs:Class ; rdfs:label "Bat coronavirus M.ful/Japan/01/2009" ; rdfs:subClassOf obo:NCBITaxon_366617 . a rdfs:Class ; rdfs:label "Candidiasis [Disease/Finding]" ; rdfs:subClassOf . obo:NCBITaxon_1582306 a rdfs:Class ; rdfs:label "Alphacoronavirus TadaridaM4" ; rdfs:subClassOf obo:NCBITaxon_366617 . obo:GO_0034641 a rdfs:Class ; rdfs:label "cellular nitrogen compound metabolic process" ; rdfs:comment "The chemical reactions and pathways involving various organic and inorganic nitrogenous compounds, as carried out by individual cells." ; rdfs:subClassOf obo:GO_0006807 , obo:GO_0044237 . obo:VO_0001745 a rdfs:Class ; rdfs:label "Canine Coronavirus Modified Live Virus Vaccine (USDA: 14P1.20)" ; rdfs:subClassOf obo:VO_0000932 . obo:PR_000003894 a rdfs:Class ; rdfs:label "A-kinase anchor protein 8" ; rdfs:comment "A protein that is a translation product of the human AKAP8 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:CHEBI_52209 a rdfs:Class ; rdfs:label "aetiopathogenetic role" ; rdfs:comment "A role played by the molecular entity or part thereof which causes the development of a pathological process." ; rdfs:subClassOf obo:CHEBI_24432 . obo:CHEBI_33713 a rdfs:Class ; rdfs:label "C-terminal alpha-amino-acid residue" ; rdfs:comment "Any C-terminal amino-acid residue derived from an alpha-amino-acid." ; rdfs:subClassOf obo:CHEBI_33710 , obo:CHEBI_33711 . a rdfs:Class ; rdfs:label "Gastrointestinal Diseases [Disease/Finding]" ; rdfs:subClassOf . obo:PR_000016551 a rdfs:Class ; rdfs:label "torsin-1A-interacting protein 1" ; rdfs:comment "A protein that is a translation product of the human TOR1AIP1 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:OBI_0000857 a rdfs:Class ; rdfs:label "complementary nucleotide probe role" ; rdfs:comment "A role played by a nucleic acid molecule that is used in a planned process for its ability to bind a nucleic acid molecules with complementary nucleotide sequence" ; rdfs:subClassOf obo:BFO_0000023 . obo:PR_P08631 a rdfs:Class ; rdfs:label "tyrosine-protein kinase HCK (human)" ; rdfs:comment "A tyrosine-protein kinase HCK that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000008473 , obo:PR_000029067 . obo:PR_000000013 a rdfs:Class ; rdfs:label "cullin" ; rdfs:comment "A protein with a core domain composition consisting of a cullin domain that functions as a molecular scaffold responsible for assembling the ROC1/Rbx1 RING-based E3 ubiquitin ligases." ; rdfs:subClassOf obo:PR_000000001 . obo:CIDO_0000674 a rdfs:Class ; rdfs:label "K417N in SARS-CoV-2 S protein" ; rdfs:comment "An AA mutation or AA variant that has mutated an amino acid at position 417 into a asparagine in S protein." ; rdfs:subClassOf obo:CIDO_0000593 . obo:PR_000018932 a rdfs:Class ; rdfs:label "angiotensinogen proteolytic cleavage product" ; rdfs:comment "An angiotensinogen, signal peptide removed form that has been processed by proteolytic cleavage." ; rdfs:subClassOf obo:PR_000018264 , obo:PR_000018931 . obo:CHEBI_46746 a rdfs:Class ; rdfs:label "triazolopyridine" ; rdfs:subClassOf obo:CHEBI_27171 , obo:CHEBI_38101 . obo:CHEBI_90628 a rdfs:Class ; rdfs:label "benzyl ester" ; rdfs:subClassOf obo:CHEBI_33308 . obo:VO_0000636 a rdfs:Class ; rdfs:label "recombinant vector vaccine role"@en ; rdfs:comment "a vaccine role that indicates the vaccine being a recombinant vector vaccine. " ; rdfs:subClassOf obo:VO_0000615 . obo:PR_000001375 a rdfs:Class ; rdfs:label "interleukin-17 receptor A" ; rdfs:comment "A protein that is a translation product of the human IL17RA gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:NCBITaxon_745725 a rdfs:Class ; rdfs:label "Coronavirus N.noc/VM176/2007/NLD" ; rdfs:subClassOf obo:NCBITaxon_696098 . obo:CIDO_0020313 a rdfs:Class ; rdfs:label "UCSD RC SARS-CoV-2 Assay" ; rdfs:seeAlso ; rdfs:subClassOf obo:CIDO_0000454 . obo:PR_000016048 a rdfs:Class ; rdfs:label "serine/threonine-protein kinase TAO1" ; rdfs:comment "A protein that is a translation product of the human TAOK1 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:NCBITaxon_1298362 a rdfs:Class ; rdfs:label "Human betacoronavirus 2c England-Qatar/2012" ; rdfs:subClassOf obo:NCBITaxon_1335626 . obo:NCBITaxon_1746083 a rdfs:Class ; rdfs:label "Bat coronavirus M.bech/GER/8355/2014" ; rdfs:subClassOf obo:NCBITaxon_2664420 . a rdfs:Class ; rdfs:label "Deoxyribonucleosides [Chemical/Ingredient]" ; rdfs:subClassOf . obo:PR_000015144 a rdfs:Class ; rdfs:label "choline transporter-like protein 2" ; rdfs:comment "A protein that is a translation product of the human SLC44A2 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:ICDO_0000001 a rdfs:Class ; rdfs:label "disease process"@en , "疾病过程"@zh ; rdfs:comment "Disease process is the progression disease in an individual over time. The process begins with the appropriate exposure to or accumulation of factors sufficient for the disease process to begin in a susceptible host. For an infectious disease, the exposure is a microorganism. For cancer, the exposure may be a factor that initiates the process, such as asbestos fibers or components in tobacco smoke (for lung cancer), or one that promotes the process, such as estrogen (for endometrial cancer)." ; rdfs:subClassOf obo:OGMS_0000061 . a rdfs:Class ; rdfs:label "Nutritional and Metabolic Diseases [Disease/Finding]" ; rdfs:subClassOf . obo:PR_Q02750 a rdfs:Class ; rdfs:label "dual specificity mitogen-activated protein kinase kinase 1 (human)" ; rdfs:comment "A dual specificity mitogen-activated protein kinase kinase 1 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000010125 , obo:PR_000029067 . obo:OPMI_0000533 a rdfs:Class ; rdfs:label "medical condition status"@en ; rdfs:comment "The state or status at the point during the visit the diagnosis was given (admitting diagnosis, final diagnosis), whether the diagnosis was determined due to laboratory findings, if the diagnosis was exclusionary, or if it was a preliminary diagnosis, among others." ; rdfs:subClassOf obo:BFO_0000017 . obo:CHEBI_76869 a rdfs:Class ; rdfs:label "EC 1.8.1.* (oxidoreductase acting on sulfur group of donors, NAD(+) or NADP(+) as acceptor) inhibitor" ; rdfs:comment "An EC 1.8.* (oxidoreductase acting on sulfur group of donors) inhibitor that interferes with the action of any such enzyme using NAD(+) or NADP(+) as acceptor (EC 1.8.1.*)." ; rdfs:subClassOf obo:CHEBI_76735 . a rdfs:Class ; rdfs:label "Stimulate Uterine Secretory Phase [PE]" ; rdfs:subClassOf . obo:OGG_3043740569 a rdfs:Class ; rdfs:label "ORF3a of severe acute respiratory syndrome coronavirus 2" ; rdfs:subClassOf obo:OGG_2002697049 . obo:PR_O14975 a rdfs:Class ; rdfs:label "very long-chain acyl-CoA synthetase (human)" ; rdfs:comment "A very long-chain acyl-CoA synthetase that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000015046 , obo:PR_000029067 . obo:NCBITaxon_264380 a rdfs:Class ; rdfs:label "SARS coronavirus TW-GD3" ; rdfs:subClassOf obo:NCBITaxon_264370 . obo:GO_0006614 a rdfs:Class ; rdfs:label "SRP-dependent cotranslational protein targeting to membrane" ; rdfs:comment "The targeting of proteins to a membrane that occurs during translation and is dependent upon two key components, the signal-recognition particle (SRP) and the SRP receptor. SRP is a cytosolic particle that transiently binds to the endoplasmic reticulum (ER) signal sequence in a nascent protein, to the large ribosomal unit, and to the SRP receptor in the ER membrane." ; rdfs:subClassOf obo:GO_0006612 , obo:GO_0045047 . obo:CHEBI_149553 a rdfs:Class ; rdfs:label "anticoronaviral agent" ; rdfs:comment "Any antiviral agent which inhibits the activity of coronaviruses." ; rdfs:subClassOf obo:CHEBI_22587 . obo:NCBITaxon_622708 a rdfs:Class ; rdfs:label "Bat coronavirus Hipposideros/GhanaBoo/348/2008" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:PR_P00533 a rdfs:Class ; rdfs:label "epidermal growth factor receptor (human)" ; rdfs:comment "An epidermal growth factor receptor that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000006933 , obo:PR_000029067 . obo:PATO_0000146 a rdfs:Class ; rdfs:label "temperature" ; rdfs:comment "A physical quality of the thermal energy of a system." ; rdfs:subClassOf obo:PATO_0001018 . obo:CHEBI_22715 a rdfs:Class ; rdfs:label "benzimidazoles" ; rdfs:comment "An organic heterocyclic compound containing a benzene ring fused to an imidazole ring." ; rdfs:subClassOf obo:CHEBI_27171 , obo:CHEBI_38101 . obo:GO_0002376 a rdfs:Class ; rdfs:label "immune system process" ; rdfs:comment "Any process involved in the development or functioning of the immune system, an organismal system for calibrated responses to potential internal or invasive threats." ; rdfs:subClassOf obo:GO_0008150 . obo:NCBITaxon_903615 a rdfs:Class ; rdfs:label "Kenya bat coronavirus BtKY77" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:NCBITaxon_1241933 a rdfs:Class ; rdfs:label "Rousettus bat coronavirus HKU10" ; rdfs:subClassOf obo:NCBITaxon_1244203 . obo:NCBITaxon_2042700 a rdfs:Class ; rdfs:label "Bat coronavirus A977/A970" ; rdfs:subClassOf obo:NCBITaxon_366617 . obo:NCBITaxon_1679928 a rdfs:Class ; rdfs:label "Coronavirus Rabbit_CoV/La09_48/Ory_cun/ESP/2009" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:CHEBI_33702 a rdfs:Class ; rdfs:label "polyatomic cation" ; rdfs:comment "A cation consisting of more than one atom." ; rdfs:subClassOf obo:CHEBI_36358 , obo:CHEBI_36916 . obo:CHEBI_59517 a rdfs:Class ; rdfs:label "DNA synthesis inhibitor" ; rdfs:comment "Any substance that inhibits the synthesis of DNA." ; rdfs:subClassOf obo:CHEBI_76932 . obo:CHEBI_35692 a rdfs:Class ; rdfs:label "dicarboxylic acid" ; rdfs:comment "Any carboxylic acid containing two carboxy groups." ; rdfs:subClassOf obo:CHEBI_131927 , obo:CHEBI_33575 . obo:PR_Q14680 a rdfs:Class ; rdfs:label "maternal embryonic leucine zipper kinase (human)" ; rdfs:comment "A maternal embryonic leucine zipper kinase that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000010319 , obo:PR_000029067 . obo:OPMI_0000540 a rdfs:Class ; rdfs:label "preliminary diagnosis status"@en ; rdfs:subClassOf obo:OPMI_0000533 . obo:OAE_0000162 a rdfs:Class ; rdfs:label "sensory neuropathy AE" ; rdfs:comment "a peripheral neuropathy AE which has an outcome of sensory neuropathy that involves damage to nerves of the peripheral nervous system." ; rdfs:subClassOf obo:OAE_0000418 . a rdfs:Class ; rdfs:label "Neoplastic Processes [Disease/Finding]" ; rdfs:subClassOf , . obo:NCBITaxon_1346309 a rdfs:Class ; rdfs:label "Betacoronavirus BtCoV/Rhi_hip/R46-03/SPA/2010" ; rdfs:subClassOf obo:NCBITaxon_696098 . obo:OPMI_0000505 a rdfs:Class ; rdfs:label "procedure occurrence"@en ; rdfs:comment "An activity or process that is ordered by, or carried out by, a healthcare provider on a patient with a diagnostic or therapeutic purpose." ; rdfs:subClassOf obo:BFO_0000015 . obo:CHEBI_22063 a rdfs:Class ; rdfs:label "sulfoxide" ; rdfs:comment "An organosulfur compound having the structure R2S=O or R2C=S=O (R =/= H)." ; rdfs:subClassOf obo:CHEBI_33261 . obo:PR_000010430 a rdfs:Class ; rdfs:label "MAP kinase-interacting serine/threonine-protein kinase 2" ; rdfs:comment "A protein that is a translation product of the human MKNK2 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:DRON_00025622 a rdfs:Class ; rdfs:label "gemcitabine Injectable Solution" ; rdfs:subClassOf obo:DRON_00000020 . obo:NCBITaxon_11124 a rdfs:Class ; rdfs:label "Avian infectious bronchitis virus (strain D274)" ; rdfs:subClassOf obo:NCBITaxon_11120 . obo:PR_P0DTD8 a rdfs:Class ; rdfs:label "ORF7b protein (SARS-CoV-2)" ; rdfs:comment "A protein that is a translation product of the ORF7b gene in SARS-CoV-2." ; rdfs:subClassOf obo:PR_000050262 . obo:PR_P13501 a rdfs:Class ; rdfs:label "C-C motif chemokine 5 (human)" ; rdfs:comment "A C-C motif chemokine 5 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000002094 , obo:PR_000029067 . obo:PR_P0DTC8 a rdfs:Class ; rdfs:label "ORF8 protein (SARS-CoV-2)" ; rdfs:comment "A protein that is a translation product of the ORF8 gene in SARS-CoV-2." ; rdfs:subClassOf obo:PR_000050262 . obo:CIDO_0000341 a rdfs:Class ; rdfs:label "ELDKYFKNHTSPDVD"@en ; rdfs:subClassOf obo:CIDO_0000314 . obo:PR_000011093 a rdfs:Class ; rdfs:label "NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9" ; rdfs:comment "A protein that is a translation product of the human NDUFB9 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:PR_Q32MK0 a rdfs:Class ; rdfs:label "myosin light chain kinase 3 (human)" ; rdfs:comment "A myosin light chain kinase 3 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000029067 , obo:PR_000029126 . obo:PR_P62330 a rdfs:Class ; rdfs:label "ADP-ribosylation factor 6 (human)" ; rdfs:comment "An ADP-ribosylation factor 6 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000004205 , obo:PR_000029067 . obo:HP_0040069 a rdfs:Class ; rdfs:label "Abnormal lower limb bone morphology" ; rdfs:subClassOf obo:HP_0002813 , obo:HP_0002814 . obo:CHEBI_6538 a rdfs:Class ; rdfs:label "loratadine" ; rdfs:comment "A benzocycloheptapyridine that is 6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridine substituted by a chloro group at position 8 and a 1-(ethoxycarbonyl)piperidin-4-ylidene group at position 11. It is a H1-receptor antagonist commonly employed in the treatment of allergic disorders." ; rdfs:subClassOf obo:CHEBI_140326 , obo:CHEBI_23990 , obo:CHEBI_36683 , obo:CHEBI_48591 , obo:CHEBI_48593 . obo:NCBITaxon_1381358 a rdfs:Class ; rdfs:label "Bat Coronavirus Rhhar/CII_KSA_004/Bisha/Saudi Arabia/2013" ; rdfs:subClassOf obo:NCBITaxon_696098 . obo:NCBITaxon_389232 a rdfs:Class ; rdfs:label "Bat coronavirus (BtCoV/301/2005)" ; rdfs:subClassOf obo:NCBITaxon_389126 . obo:CHEBI_86327 a rdfs:Class ; rdfs:label "antifungal drug" ; rdfs:comment "Any antifungal agent used to prevent or treat fungal infections in humans or animals." ; rdfs:subClassOf obo:CHEBI_23888 , obo:CHEBI_35441 , obo:CHEBI_35718 . a rdfs:Class ; rdfs:label "Cetylpyridinium Chloride [Chemical/Ingredient]" ; rdfs:subClassOf . obo:CHEBI_36820 a rdfs:Class ; rdfs:label "ring assembly" ; rdfs:comment "Two or more cyclic systems (single rings or fused systems) which are directly joined to each other by double or single bonds are named ring assemblies when the number of such direct ring junctions is one less than the number of cyclic systems involved." ; rdfs:subClassOf obo:CHEBI_33595 . obo:CHEBI_36836 a rdfs:Class ; rdfs:label "3beta-hydroxy steroid" ; rdfs:comment "A 3-hydroxy steroid in which the 3-hydroxy substituent is in the beta-position." ; rdfs:subClassOf obo:CHEBI_35681 , obo:CHEBI_36834 . a rdfs:Class ; rdfs:label "Hydrocarbons, Alicyclic [Chemical/Ingredient]" ; rdfs:subClassOf . obo:OBI_2000005 a rdfs:Class ; rdfs:label "respiratory system specimen" ; rdfs:comment "A specimen that is derived from some respiratory system " ; rdfs:subClassOf obo:OBI_0001479 . obo:CIDO_0000291 a rdfs:Class ; rdfs:label "symptomic human infected with pathogen"@en ; rdfs:subClassOf obo:CIDO_0000290 . obo:PR_000004988 a rdfs:Class ; rdfs:label "calcium/calmodulin-dependent protein kinase type 1" ; rdfs:comment "A protein that is a translation product of the human CAMK1 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:PR_P53355 a rdfs:Class ; rdfs:label "death-associated protein kinase 1 (human)" ; rdfs:comment "A death-associated protein kinase 1 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000006276 , obo:PR_000029067 . obo:OBI_0002784 a rdfs:Class ; rdfs:label "anterior nasal swab specimen" ; rdfs:comment "A specimen that is derived from the anterior nasal wall" ; rdfs:subClassOf obo:OBI_0002599 . obo:NCBITaxon_229033 a rdfs:Class ; rdfs:label "Porcine epidemic diarrhea virus Br1/87" ; rdfs:subClassOf obo:NCBITaxon_28295 . obo:CHEBI_16196 a rdfs:Class ; rdfs:label "oleic acid" ; rdfs:comment "An octadec-9-enoic acid in which the double bond at C-9 has Z (cis) stereochemistry." ; rdfs:subClassOf obo:CHEBI_36021 . obo:CIDO_0001110 a rdfs:Class ; rdfs:label "SARS-CoV2 orf9b protein binding to human DCTPP1"@en ; rdfs:comment "SARS-CoV2 orf9b protein binding to human DCTPP1, as evidented by an affinity-purification mass spectrometry experiment" ; rdfs:subClassOf obo:CIDO_0000052 . a rdfs:Class ; rdfs:label "Terfenadine [Chemical/Ingredient]" ; rdfs:subClassOf , . obo:PR_P48729 a rdfs:Class ; rdfs:label "casein kinase I isoform alpha (human)" ; rdfs:comment "A casein kinase I isoform alpha that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000005943 , obo:PR_000029067 . obo:PR_000006884 a rdfs:Class ; rdfs:label "evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial" ; rdfs:comment "A protein that is a translation product of the human ECSIT gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:NCBITaxon_1146849 a rdfs:Class ; rdfs:label "Bat coronavirus M.daubentonii/UK/Wyt/971Co" ; rdfs:subClassOf obo:NCBITaxon_366617 . obo:CIDO_0020332 a rdfs:Class ; rdfs:label "WANTAI SARS-CoV-2 Ab Rapid Test" ; rdfs:seeAlso ; rdfs:subClassOf obo:CIDO_0000454 . obo:CHEBI_38716 a rdfs:Class ; rdfs:label "carboxylic acid dianion" ; rdfs:comment "Any dianion containing at least one carboxy group." ; rdfs:subClassOf obo:CHEBI_29067 . a rdfs:Class ; rdfs:label "Menstruation Disturbances [Disease/Finding]" ; rdfs:subClassOf . obo:NCBITaxon_1679903 a rdfs:Class ; rdfs:label "Coronavirus RCoV/D_RMU10_986/Myo_gla/GER/2010" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:IAO_0000065 a rdfs:Class ; rdfs:label "software interpreter"@en ; rdfs:comment "A software interpreter is a software application that executes some specified input software."@en ; rdfs:subClassOf obo:IAO_0000064 . obo:PR_000036008 a rdfs:Class ; rdfs:label "angiotensin I" ; rdfs:comment "An angiotensinogen proteolytic cleavage product that is formed via the action of renin on angiotensinogen, signal peptide removed form." ; rdfs:subClassOf obo:PR_000018932 . obo:CHEBI_51454 a rdfs:Class ; rdfs:label "cyclopropanes" ; rdfs:comment "Cyclopropane and its derivatives formed by substitution." ; rdfs:subClassOf obo:CHEBI_33598 . obo:NCBITaxon_2042699 a rdfs:Class ; rdfs:label "Myotis alphacoronavirus" ; rdfs:subClassOf obo:NCBITaxon_366617 . obo:NCBITaxon_931894 a rdfs:Class ; rdfs:label "Alphacoronavirus Eptesicus fuscus/Appalachian Ridge/P3-C766/IT/USA/2009" ; rdfs:subClassOf obo:NCBITaxon_366617 . obo:HP_0002870 a rdfs:Class ; rdfs:label "Obstructive sleep apnea" ; rdfs:comment "A condition characterized by obstruction of the airway and by pauses in breathing during sleep occurring many times during the night. Obstructive sleep apnea is related to a relaxation of muscle tone (which normally occurs during sleep) leading to partial collapse of the soft tissues in the airway with resultant obstruction of the air flow." ; rdfs:subClassOf obo:HP_0010535 . obo:CHEBI_7507 a rdfs:Class ; rdfs:label "Neomycin" ; rdfs:comment "A broad-spectrum highly toxic antibiotic or mixture of antibiotics produced by a streptomyces (Streptomyces fradiae) and used medically especially to treat local infections." ; rdfs:subClassOf obo:CHEBI_22479 , obo:CHEBI_22507 . obo:CHEBI_23004 a rdfs:Class ; rdfs:label "carbamoyl group" ; rdfs:comment "The univalent carboacyl group formed by loss of -OH from the carboxy group of carbamic acid." ; rdfs:subClassOf obo:CHEBI_27207 . obo:CHEBI_76760 a rdfs:Class ; rdfs:label "EC 3.1.* (ester hydrolase) inhibitor" ; rdfs:comment "A hydrolase inhibitor that interferes with the action of any ester hydrolase (EC 3.1.*.*)." ; rdfs:subClassOf obo:CHEBI_76759 . obo:CHEBI_90688 a rdfs:Class ; rdfs:label "metformin(1+)" ; rdfs:comment "A guanidinium ion obtained by monoprotonation of metformin." ; rdfs:subClassOf obo:CHEBI_60251 . obo:CHEBI_94448 a rdfs:Class ; rdfs:label "1-[2-[(4-chlorophenyl)-phenylmethoxy]ethyl]piperidine" ; rdfs:subClassOf obo:CHEBI_51614 . obo:CIDO_0020014 a rdfs:Class ; rdfs:label "AIT Laboratories SARS-CoV-2 Assay" ; rdfs:seeAlso ; rdfs:subClassOf obo:CIDO_0000454 . obo:OBI_0002517 a rdfs:Class ; rdfs:label "hair specimen" ; rdfs:comment "A specimen that is derived from hair." ; rdfs:subClassOf obo:OBI_0001479 . a rdfs:Class ; rdfs:label "RITONAVIR" ; rdfs:subClassOf . obo:NCBITaxon_231431 a rdfs:Class ; rdfs:label "Turkey coronavirus (strain NC95)" ; rdfs:subClassOf obo:NCBITaxon_11152 . obo:NCBITaxon_422216 a rdfs:Class ; rdfs:label "Bovine coronavirus E-DB2-TC" ; rdfs:subClassOf obo:NCBITaxon_11128 . a rdfs:Class ; rdfs:label "Renal Insufficiency [Disease/Finding]" ; rdfs:subClassOf . obo:PR_000009071 a rdfs:Class ; rdfs:label "integrator complex subunit 4" ; rdfs:comment "A protein that is a translation product of the human INTS4 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:PR_000003278 a rdfs:Class ; rdfs:label "serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform" ; rdfs:comment "A protein that is a translation product of the human PPP3CA gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:CIDO_0020289 a rdfs:Class ; rdfs:label "SGTi-flex COVID-19 IgG" ; rdfs:seeAlso ; rdfs:subClassOf obo:CIDO_0000454 . obo:CIDO_0001078 a rdfs:Class ; rdfs:label "AA variant in SARS-CoV-2 nsp7 protein"@en ; rdfs:comment "An AA variant in SARS-CoV-2 nsp7 protein. Equivalent to an AA variant in SARS-CoV-2 rep 1ab with an AA position of 3837 - 3919." ; rdfs:subClassOf obo:CIDO_0000714 . obo:CHEBI_63681 a rdfs:Class ; rdfs:label "[2,8-bis(trifluoromethyl)quinolin-4-yl]-(2-piperidyl)methanol" ; rdfs:comment "An organofluorine compound that consists of quinoline bearing trifluoromethyl substituents at positions 2 and 8 as well as a (2-piperidinyl)hydroxymethyl substituent at position 4." ; rdfs:subClassOf obo:CHEBI_26151 , obo:CHEBI_26513 , obo:CHEBI_35681 , obo:CHEBI_37143 . obo:OAE_0000084 a rdfs:Class ; rdfs:label "cardiac disorder AE" ; rdfs:comment "a cardiovascular disorder AE that has a cardiac disorder outcome. " ; rdfs:subClassOf obo:OAE_0000493 . obo:CHEBI_76595 a rdfs:Class ; rdfs:label "nephroprotective agent" ; rdfs:comment "Any protective agent that is able to prevent damage to the kidney." ; rdfs:subClassOf obo:CHEBI_50267 . obo:UBERON_0001826 a rdfs:Class ; rdfs:label "nasal cavity mucosa" ; rdfs:comment "The mucous membrane that lines the nasal cavity[MP]." ; rdfs:subClassOf obo:UBERON_0000465 . obo:CIDO_0000099 a rdfs:Class ; rdfs:label "interruption to SARS-CoV-2 infection"@en ; rdfs:comment "A process that interrupts SARS-CoV-2 viral infection in host" ; rdfs:subClassOf obo:CIDO_0000098 . obo:GO_0005272 a rdfs:Class ; rdfs:label "sodium channel activity" ; rdfs:comment "Enables the facilitated diffusion of a sodium ion (by an energy-independent process) involving passage through a transmembrane aqueous pore or channel without evidence for a carrier-mediated mechanism." ; rdfs:subClassOf obo:GO_0005261 , obo:GO_0046873 . obo:NCBITaxon_366617 a rdfs:Class ; rdfs:label "unclassified Alphacoronavirus" ; rdfs:subClassOf obo:NCBITaxon_693996 . obo:NCBITaxon_2115988 a rdfs:Class ; rdfs:label "Swine acute diarrhea syndrome related coronavirus" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:CHEBI_24531 a rdfs:Class ; rdfs:label "heterocyclic antibiotic" ; rdfs:subClassOf obo:CHEBI_24532 . obo:CIDO_0020068 a rdfs:Class ; rdfs:label "CareStart COVID-19 IgM/IgG" ; rdfs:seeAlso ; rdfs:subClassOf obo:CIDO_0000454 . obo:CHEBI_48578 a rdfs:Class ; rdfs:label "radical scavenger" ; rdfs:comment "A role played by a substance that can react readily with, and thereby eliminate, radicals." ; rdfs:subClassOf obo:CHEBI_22586 . obo:PR_000001291 a rdfs:Class ; rdfs:label "C-type asialoglycoprotein receptor" ; rdfs:comment "A protein that is an integral membrane protein and is responsible for the clearance of desialylated, galactose-terminal glycoproteins from the circulation by receptor-mediated endocytosis. It can be subdivided into four functional domains: the cytosolic domain, the transmembrane domain, the stalk and the carbohydrate recognition domain (CRD). The functional receptor, a galactose lectin, is an oligomer of two types of similar polypeptide chains, each of which weakly binds galactose. High-affinity binding of complex oligosaccharides requires a precise geometric arrangement of receptor subunits. The two subunits have different functions in receptor assembly, ligand binding and endocytosis." ; rdfs:subClassOf obo:PR_000000001 . obo:NCBITaxon_1429864 a rdfs:Class ; rdfs:label "Betacoronavirus Rhinolophus hipposideros/Italy/187632-2/2012" ; rdfs:subClassOf obo:NCBITaxon_696098 . obo:GO_0050795 a rdfs:Class ; rdfs:label "regulation of behavior" ; rdfs:comment "Any process that modulates the frequency, rate or extent of behavior, the internally coordinated responses (actions or inactions) of whole living organisms (individuals or groups) to internal or external stimuli." ; rdfs:subClassOf obo:GO_0051239 . obo:GO_0010647 a rdfs:Class ; rdfs:label "positive regulation of cell communication" ; rdfs:comment "Any process that increases the frequency, rate or extent of cell communication. Cell communication is the process that mediates interactions between a cell and its surroundings. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment." ; rdfs:subClassOf obo:GO_0010646 , obo:GO_0048522 . a rdfs:Class ; rdfs:label "Intestinal Obstruction [Disease/Finding]" ; rdfs:subClassOf . obo:PR_Q8IWR1 a rdfs:Class ; rdfs:label "tripartite motif-containing protein 59 (human)" ; rdfs:comment "A tripartite motif-containing protein 59 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000029067 , obo:PR_000031980 . obo:NCBITaxon_1699360 a rdfs:Class ; rdfs:label "Bat SARS-like coronavirus YNLF_31C" ; rdfs:subClassOf obo:NCBITaxon_694009 . obo:CIDO_0000236 a rdfs:Class ; rdfs:label "SARS-CoV-2 clade O virus"@en ; rdfs:comment "a SARS-CoV-2 virus that belongs to clade O, which stands for \"Other\", meaning it is not G, GH, GR, L, S, or V." ; rdfs:subClassOf obo:CIDO_0000405 . obo:PR_P54762 a rdfs:Class ; rdfs:label "ephrin type-B receptor 1 (human)" ; rdfs:comment "An ephrin type-B receptor 1 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000007129 , obo:PR_000029067 . obo:CHEBI_65001 a rdfs:Class ; rdfs:label "EC 3.1.1.3 (triacylglycerol lipase) inhibitor" ; rdfs:comment "Any EC 3.1.1.* (carboxylic ester hydrolase) inhibitor that inhibits the action of triacylglycerol lipase (EC 3.1.1.3)." ; rdfs:subClassOf obo:CHEBI_76773 . a rdfs:Class ; rdfs:label "Kidney Neoplasms [Disease/Finding]" ; rdfs:subClassOf , . obo:CIDO_0020248 a rdfs:Class ; rdfs:label "qSARS-CoV-2 IgM/IgG Rapid Test" ; rdfs:seeAlso ; rdfs:subClassOf obo:CIDO_0000454 . obo:IDO_0000496 a rdfs:Class ; rdfs:label "long-term non-progressing infectious disease course"@en ; rdfs:comment "A chronic infectious disease course that does not progress to severe stages for a long period of time."@en ; rdfs:subClassOf obo:IDO_0000590 . obo:UBERON_0000316 a rdfs:Class ; rdfs:label "cervical mucus" ; rdfs:comment "A substance produced by the cervix and endocervical glands[BTO]. Thick acidic mucus that blocks the cervical os after mestruation[WP]. This 'infertile' mucus blocks spermatozoa from entering the uterus." ; rdfs:subClassOf obo:UBERON_0006314 . obo:VO_0005311 a rdfs:Class ; rdfs:label "Th1/Th2 mixed immune profile"@en ; rdfs:comment "An immune profile that is characterized by the presense of both Type 1 and Type 2 T helper (Th1 and Th2) cells." ; rdfs:subClassOf obo:VO_0005308 . obo:CHEBI_47985 a rdfs:Class ; rdfs:label "enol ether" ; rdfs:comment "Ethers ROR' where R has a double bond adjacent to the oxygen of the ether linkage." ; rdfs:subClassOf obo:CHEBI_25698 , obo:CHEBI_78840 . obo:OBI_0000372 a rdfs:Class ; rdfs:label "material separation function"@en ; rdfs:comment "A material separation function is a function that increases the resolution between two or more material entities. The to distinction between the entities is usually based on some associated physical quality."@en ; rdfs:subClassOf obo:BFO_0000034 . obo:CHEBI_75282 a rdfs:Class ; rdfs:label "ergosterol biosynthesis inhibitor" ; rdfs:comment "Any compound that inhibits one or more steps in the pathway leading to the synthesis of ergosterol." ; rdfs:subClassOf obo:CHEBI_83317 . a rdfs:Class ; rdfs:label "NITAZOXANIDE" ; rdfs:subClassOf . obo:VO_0005235 a rdfs:Class ; rdfs:label "NDV-HXP-S"@en ; rdfs:comment "A SARS-CoV-2 recombinant viral vector vaccine by Mahidol University" ; rdfs:subClassOf obo:VO_0005199 . obo:HP_0002814 a rdfs:Class ; rdfs:label "Abnormality of the lower limb" ; rdfs:comment "An abnormality of the leg." ; rdfs:subClassOf obo:HP_0040064 . obo:PR_000011454 a rdfs:Class ; rdfs:label "cytosolic purine 5'-nucleotidase" ; rdfs:comment "A protein that is a translation product of the human NT5C2 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:VO_0004991 a rdfs:Class ; rdfs:label "COVAXIN"@en ; rdfs:comment "BBV152 (also known as Covaxin) is an inactivated COVID-19 vaccine that is developed by Bharat Biotech in collaboration with the Indian Council of Medical Research." ; rdfs:subClassOf obo:VO_0005266 . obo:PR_P00387 a rdfs:Class ; rdfs:label "NADH-cytochrome b5 reductase 3 (human)" ; rdfs:comment "An NADH-cytochrome b5 reductase 3 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000006082 , obo:PR_000029067 . obo:CHEBI_113532 a rdfs:Class ; rdfs:label "thymoquinone" ; rdfs:comment "A member of the class of 1,4-benzoquinones that is 1,4-bezoquinone in which the hydrogens at positions 2 and 5 are replaced by methyl and isopropyl groups, respectively. It is a natural compound isolated from Nigella sativa which has demonstrated promising chemotherapeutic activity." ; rdfs:subClassOf obo:CHEBI_132124 . obo:PR_Q13153 a rdfs:Class ; rdfs:label "serine/threonine-protein kinase PAK 1 (human)" ; rdfs:comment "A serine/threonine-protein kinase PAK 1 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000012239 , obo:PR_000029067 . obo:CIDO_0000518 a rdfs:Class ; rdfs:label "RIAGRSALEDLLFSK" ; rdfs:comment "A coronavirus epitope that is part of some S protein from HCoV NL63 composed of the following amino acids RIAGRSALEDLLFSK" ; rdfs:subClassOf obo:CIDO_0000449 . a rdfs:Class ; rdfs:label "Hypoxanthines [Chemical/Ingredient]" ; rdfs:subClassOf . obo:CIDO_0000374 a rdfs:Class ; rdfs:label "oxygen mask"@en ; rdfs:comment "A kit or equipment designed for a medical purpose." ; rdfs:subClassOf obo:CIDO_0000372 . obo:CHEBI_72544 a rdfs:Class ; rdfs:label "flavonoids" ; rdfs:comment "Any organic molecular entity whose stucture is based on derivatives of a phenyl-substituted 1-phenylpropane possessing a C15 or C16 skeleton, or such a structure which is condensed with a C6-C3 lignan precursors. The term is a 'superclass' comprising all members of the classes of flavonoid, isoflavonoid, neoflavonoid, chalcones, dihydrochalcones, aurones, pterocarpan, coumestans, rotenoid, flavonolignan, homoflavonoid and flavonoid oligomers. Originally restricted to natural products, the term is also applied to synthetic compounds related to them." ; rdfs:subClassOf obo:CHEBI_25806 , obo:CHEBI_50860 . obo:PR_000010195 a rdfs:Class ; rdfs:label "microtubule-associated serine/threonine-protein kinase 1" ; rdfs:comment "A protein that is a translation product of the human MAST1 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:PR_000001564 a rdfs:Class ; rdfs:label "histamine H3 receptor" ; rdfs:comment "A histamine receptor that is a translation product of the human HRH3 gene or a 1:1 ortholog thereof. The preferred ligand is histamine. This receptor mediates inhibition of gastric acid release, inhibition of neurotransmitter release, and other diverse effects." ; rdfs:subClassOf obo:PR_000049994 . obo:GO_0043043 a rdfs:Class ; rdfs:label "peptide biosynthetic process" ; rdfs:comment "The chemical reactions and pathways resulting in the formation of peptides, compounds of 2 or more (but usually less than 100) amino acids where the alpha carboxyl group of one is bound to the alpha amino group of another. This may include the translation of a precursor protein and its subsequent processing into a functional peptide." ; rdfs:subClassOf obo:GO_0006518 , obo:GO_0043604 , obo:GO_1901566 . obo:NCBITaxon_1699359 a rdfs:Class ; rdfs:label "Hipposideros Bat Alphacoronavirus strain MJ_67C" ; rdfs:subClassOf obo:NCBITaxon_366617 . a rdfs:Class ; rdfs:label "Receptor Tyrosine Kinase Inhibitors [MoA]" ; rdfs:subClassOf . obo:HP_0001701 a rdfs:Class ; rdfs:label "Pericarditis" ; rdfs:comment "Inflammation of the sac-like covering around the heart (pericardium)." ; rdfs:subClassOf obo:HP_0001627 , obo:HP_0012649 . obo:NCBITaxon_1541210 a rdfs:Class ; rdfs:label "Bat Hp-betacoronavirus/Zhejiang2013-5" ; rdfs:subClassOf obo:NCBITaxon_696098 . obo:NCBITaxon_91561 a rdfs:Class ; rdfs:label "Artiodactyla" ; rdfs:subClassOf obo:NCBITaxon_314145 . obo:CHEBI_59897 a rdfs:Class ; rdfs:label "EC 2.7.7.49 (RNA-directed DNA polymerase) inhibitor" ; rdfs:comment "A DNA polymerase inhibitor that interferes with the activity of reverse transcriptase, EC 2.7.7.49, a viral DNA polymerase enzyme that retroviruses need in order to reproduce." ; rdfs:subClassOf obo:CHEBI_22587 , obo:CHEBI_38234 . obo:CIDO_0000255 a rdfs:Class ; rdfs:label "clathrin-mediated endocytosis inhibitor role"@en ; rdfs:subClassOf obo:CIDO_0000254 . obo:HP_0002027 a rdfs:Class ; rdfs:label "Abdominal pain" ; rdfs:comment "An unpleasant sensation characterized by physical discomfort (such as pricking, throbbing, or aching) and perceived to originate in the abdomen." ; rdfs:subClassOf obo:HP_0011458 , obo:HP_0012531 . obo:PR_000044654 a rdfs:Class ; rdfs:label "voltage-gated potassium channel protein" ; rdfs:comment "A potassium channel protein that has voltage-gated potassium channel activity. A voltage-gated potassium channel enables the transmembrane transfer of a potassium ion by a voltage-gated channel. A voltage-gated channel enables the transmembrane transfer of a solute by a channel whose open state is dependent on the voltage across the membrane in which it is embedded." ; rdfs:subClassOf obo:PR_000044655 . obo:CIDO_0001150 a rdfs:Class ; rdfs:label "SARS-CoV-2 NS8 protein amino acid deletion"@en ; rdfs:comment "A SARS-CoV-2 protein AA deletion that affected a SARS-CoV-2 NS8 protein." ; rdfs:subClassOf obo:CIDO_0000614 . obo:NCBITaxon_931906 a rdfs:Class ; rdfs:label "Alphacoronavirus Eptesicus fuscus/Appalachian Ridge/P2-C344/IT/USA/2009" ; rdfs:subClassOf obo:NCBITaxon_366617 . obo:CHEBI_59107 a rdfs:Class ; rdfs:label "EC 3.4.24.* (metalloendopeptidase) inhibitor" ; rdfs:comment "Any EC 3.4.* (hydrolases acting on peptide bond) inhibitor that interferes with the activity of a metalloendopeptidase (EC 3.4.24.*)." ; rdfs:subClassOf obo:CHEBI_37670 , obo:CHEBI_60258 . obo:CHEBI_33637 a rdfs:Class ; rdfs:label "ortho-fused compound" ; rdfs:comment "A polycyclic compound in which two rings have two, and only two, atoms in common. Such compounds have n common faces and 2n common atoms." ; rdfs:subClassOf obo:CHEBI_35293 . obo:GO_0031100 a rdfs:Class ; rdfs:label "animal organ regeneration" ; rdfs:comment "The regrowth of a lost or destroyed animal organ." ; rdfs:subClassOf obo:GO_0048513 , obo:GO_0048856 . obo:DRON_00000028 a rdfs:Class ; rdfs:label "active ingredient"@en ; rdfs:comment "a role of a scattered molecular aggregate that is part of a drug product that is realized by (1) administration of the drug to an organism followed by (2) some change in the structure or functioning of some part of the organism"@en ; rdfs:subClassOf obo:DRON_00000030 . obo:DRON_00011687 a rdfs:Class ; rdfs:label "Toremifene" ; rdfs:subClassOf obo:OBI_0000047 . obo:CIDO_0000981 a rdfs:Class ; rdfs:label "SARS-CoV2 orf6 protein binding to human MTCH1" ; rdfs:comment "SARS-CoV2 orf6 protein binding to human MTCH1, as evidented by an affinity-purification mass spectrometry experiment" ; rdfs:subClassOf obo:CIDO_0000586 . obo:GO_0051246 a rdfs:Class ; rdfs:label "regulation of protein metabolic process" ; rdfs:comment "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving a protein." ; rdfs:subClassOf obo:GO_0051171 , obo:GO_0060255 , obo:GO_0080090 . obo:NCBITaxon_1269298 a rdfs:Class ; rdfs:label "Coronavirus BtCoV/BRA344/Car_bre/BRA/2009" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:CIDO_0000793 a rdfs:Class ; rdfs:label "SARS-CoV2 nsp1 protein binding to human POLA1" ; rdfs:comment "SARS-CoV2 nsp1 protein binding to human POLA1, as evidented by an affinity-purification mass spectrometry experiment" ; rdfs:subClassOf obo:CIDO_0000062 . obo:CHEBI_32868 a rdfs:Class ; rdfs:label "D-prolinium" ; rdfs:comment "An optically active form of prolinium having D-configuration." ; rdfs:subClassOf obo:CHEBI_32872 . obo:PR_000001550 a rdfs:Class ; rdfs:label "proteinase-activated receptor" ; rdfs:comment "A rhodopsin-like G-protein coupled receptor that is a translation product of the human F2R, or F2RL1 to F2RL3 genes, 1:1 orthologs thereof, or a semi-ortholog thereof. The active form binds trypsin-related proteinases. The proteinase cleaves the mature peptide, exposing a new amino end. The new N-terminal residues act as a tethered ligand that induces activity." ; rdfs:subClassOf obo:PR_000001094 . obo:GO_0050709 a rdfs:Class ; rdfs:label "negative regulation of protein secretion" ; rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of the controlled release of a protein from a cell." ; rdfs:subClassOf obo:GO_0050708 , obo:GO_0051224 , obo:GO_1903531 . obo:PR_O15197 a rdfs:Class ; rdfs:label "ephrin type-B receptor 6 (human)" ; rdfs:comment "An ephrin type-B receptor 6 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000007133 , obo:PR_000029067 . obo:NCBITaxon_1643900 a rdfs:Class ; rdfs:label "Bat coronavirus BEM074F" ; rdfs:subClassOf obo:NCBITaxon_696098 . obo:GO_0040017 a rdfs:Class ; rdfs:label "positive regulation of locomotion" ; rdfs:comment "Any process that activates or increases the frequency, rate or extent of locomotion of a cell or organism." ; rdfs:subClassOf obo:GO_0040012 , obo:GO_0048518 . obo:CHEBI_24913 a rdfs:Class ; rdfs:label "isoprenoid" ; rdfs:comment "Any lipid formally derived from isoprene (2-methylbuta-1,3-diene), the skeleton of which can generally be discerned in repeated occurrence in the molecule. The skeleton of isoprenoids may differ from strict additivity of isoprene units by loss or shift of a fragment, commonly a methyl group. The class includes both hydrocarbons and oxygenated derivatives." ; rdfs:subClassOf obo:CHEBI_18059 , obo:CHEBI_50860 . obo:CIDO_0000097 a rdfs:Class ; rdfs:label "interruption to viral infection"@en ; rdfs:comment "A process that interrupts a viral infection in host" ; rdfs:subClassOf obo:BFO_0000015 . obo:CHEBI_64766 a rdfs:Class ; rdfs:label "cationic group" ; rdfs:comment "A group that carries an overall positive charge." ; rdfs:subClassOf obo:CHEBI_24433 . obo:NCBITaxon_300189 a rdfs:Class ; rdfs:label "Pigeon coronavirus" ; rdfs:subClassOf obo:NCBITaxon_694014 . obo:VO_0000932 a rdfs:Class ; rdfs:label "canine coronavirus vaccine" ; rdfs:subClassOf obo:VO_0004897 . obo:NCBITaxon_1788419 a rdfs:Class ; rdfs:label "Bat coronavirus HpBtCoV/3740-2" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:CHEBI_7568 a rdfs:Class ; rdfs:subClassOf obo:CIDO_0000409 . obo:NCBITaxon_2509481 a rdfs:Class ; rdfs:label "Embecovirus" ; rdfs:subClassOf obo:NCBITaxon_694002 . obo:HP_0002014 a rdfs:Class ; rdfs:label "Diarrhea" ; rdfs:comment "Abnormally increased frequency of loose or watery bowel movements." ; rdfs:subClassOf obo:HP_0011458 . obo:PR_Q16288 a rdfs:Class ; rdfs:label "NT-3 growth factor receptor (human)" ; rdfs:comment "An NT-3 growth factor receptor that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000011471 , obo:PR_000029067 . obo:CIDO_0020312 a rdfs:Class ; rdfs:label "UCLA SwabSeq COVID-19 Diagnostic Platform" ; rdfs:seeAlso ; rdfs:subClassOf obo:CIDO_0000454 . obo:CHEBI_2674 a rdfs:Class ; rdfs:label "amodiaquine" ; rdfs:comment "A quinoline having a chloro group at the 7-position and an aryl amino group at the 4-position." ; rdfs:subClassOf obo:CHEBI_33853 , obo:CHEBI_36683 , obo:CHEBI_36709 , obo:CHEBI_50995 , obo:CHEBI_50996 . obo:CHEBI_38717 a rdfs:Class ; rdfs:label "carboxylic acid trianion" ; rdfs:comment "A trianion containing at least one carboxy group." ; rdfs:subClassOf obo:CHEBI_29067 . obo:CHEBI_22702 a rdfs:Class ; rdfs:label "benzamides" ; rdfs:subClassOf obo:CHEBI_22645 . a rdfs:Class ; rdfs:label "Phenylketonurias [Disease/Finding]" ; rdfs:subClassOf , . obo:GO_0014070 a rdfs:Class ; rdfs:label "response to organic cyclic compound" ; rdfs:comment "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an organic cyclic compound stimulus." ; rdfs:subClassOf obo:GO_0010033 . a rdfs:Class ; rdfs:label "Decreased Cytokine Activity [PE]" ; rdfs:subClassOf . obo:PR_P51812 a rdfs:Class ; rdfs:label "ribosomal protein S6 kinase alpha-3 (human)" ; rdfs:comment "A ribosomal protein S6 kinase alpha-3 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000014284 , obo:PR_000029067 . obo:NCBITaxon_1076422 a rdfs:Class ; rdfs:label "Alphacoronavirus M.dau/H/Spain/2007" ; rdfs:subClassOf obo:NCBITaxon_366617 . obo:CIDO_0001132 a rdfs:Class ; rdfs:label "SARS-CoV2 orf8 protein binding to human POGLUT2"@en ; rdfs:comment "SARS-CoV2 orf8 protein binding to human POGLUT2, as evidented by an affinity-purification mass spectrometry experiment" ; rdfs:subClassOf obo:CIDO_0000051 . obo:CHEBI_47901 a rdfs:Class ; rdfs:label "alkanesulfonic acid" ; rdfs:comment "Organic derivatives of sulfonic acid in which the sulfo group is linked directly to carbon of an alkyl group." ; rdfs:subClassOf obo:CHEBI_33551 . obo:CHEBI_25224 a rdfs:Class ; rdfs:label "methanesulfonate" ; rdfs:comment "A 1,1-diunsubstituted alkanesulfonate that is the conjugate base of methanesulfonic acid." ; rdfs:subClassOf obo:CHEBI_62081 . a rdfs:Class ; rdfs:label "Inhibit Ovarian Follicular Phase [PE]" ; rdfs:subClassOf . obo:NCBITaxon_1289544 a rdfs:Class ; rdfs:label "Coronavirus Mex_CoV-1" ; rdfs:subClassOf obo:NCBITaxon_366617 . obo:CHEBI_26776 a rdfs:Class ; rdfs:label "stilbenoid" ; rdfs:comment "Any olefinic compound characterised by a 1,2-diphenylethylene backbone." ; rdfs:subClassOf obo:CHEBI_33659 , obo:CHEBI_78840 . obo:HP_0012337 a rdfs:Class ; rdfs:label "Abnormal homeostasis" ; rdfs:comment "An anomaly in the processes involved in the maintenance of an internal equilibrium." ; rdfs:subClassOf obo:HP_0001939 . obo:NCBITaxon_502100 a rdfs:Class ; rdfs:label "Feline coronavirus RM" ; rdfs:subClassOf obo:NCBITaxon_12663 . obo:CHEBI_47908 a rdfs:Class ; rdfs:label "alkanethiol" ; rdfs:comment "An alkanethiol is a compound in which a sulfanyl group, -SH, is attached to an alkyl group." ; rdfs:subClassOf obo:CHEBI_29256 . obo:CIDO_0000529 a rdfs:Class ; rdfs:label "DLLSEYGTFCDNINS" ; rdfs:comment "A coronavirus epitope that is part of some S protein from HCoV HKU1 composed of the following amino acids DLLSEYGTFCDNINS" ; rdfs:subClassOf obo:CIDO_0000450 . a rdfs:Class ; rdfs:label "Wolff-Parkinson-White Syndrome [Disease/Finding]" ; rdfs:subClassOf , . a rdfs:Class ; rdfs:label "Thromboembolism [Disease/Finding]" ; rdfs:subClassOf . obo:CHEBI_189680 a rdfs:Class ; rdfs:label "protein binder" ; rdfs:comment "A binding protein is any protein that acts as an agent to bind two or more molecules together." ; rdfs:subClassOf obo:CHEBI_50860 . obo:NCBITaxon_305414 a rdfs:Class ; rdfs:label "SARS coronavirus C018" ; rdfs:subClassOf obo:NCBITaxon_694009 . obo:PR_000007774 a rdfs:Class ; rdfs:label "gamma-aminobutyric acid receptor subunit beta-3" ; rdfs:comment "A GABA(A) receptor protein that is a translation product of the human GABRB3 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000044664 . obo:OBI_0100051 a rdfs:Class ; rdfs:label "specimen"@en ; rdfs:comment "A material entity that has the specimen role."@en ; rdfs:subClassOf obo:BFO_0000040 . a rdfs:Class ; rdfs:label "Urethral Obstruction [Disease/Finding]" ; rdfs:subClassOf . obo:NCBITaxon_983929 a rdfs:Class ; rdfs:label "Chaerephon bat coronavirus/Kenya/KY22/2006" ; rdfs:subClassOf obo:NCBITaxon_366617 . obo:CHEBI_64995 a rdfs:Class ; rdfs:label "EC 1.13.11.31 (arachidonate 12-lipoxygenase) inhibitor" ; rdfs:comment "A lipoxygenase inhibitor that interferes with the action of arachidonate 12-lipoxygenase (EC 1.13.11.31)." ; rdfs:subClassOf obo:CHEBI_35856 . obo:VO_0005230 a rdfs:Class ; rdfs:label "COVID-eVax"@en ; rdfs:comment "A SARS-CoV-2 plasmid DNA vaccine manufactured by Takis and Rottapharm Biotech" ; rdfs:subClassOf obo:VO_0005203 . obo:OPMI_0000561 a rdfs:Class ; rdfs:label "underlying cause of death status"@en ; rdfs:comment "The underlying cause of death refers to the disease or injury that initiated the train of morbid events leading directly to death or the circumstances of the accident or violence that produced the injury." ; rdfs:subClassOf obo:OPMI_0000543 . obo:NCBITaxon_389248 a rdfs:Class ; rdfs:label "Bat coronavirus (BtCoV/A1206/2005)" ; rdfs:subClassOf obo:NCBITaxon_389126 . obo:CHEBI_22160 a rdfs:Class ; rdfs:label "acetamides" ; rdfs:comment "Compounds with the general formula RNHC(=O)CH3." ; rdfs:subClassOf obo:CHEBI_37622 . obo:OAE_0000493 a rdfs:Class ; rdfs:label "cardiovascular AE" ; rdfs:comment "an AE that occurs in cardiovascular system." ; rdfs:subClassOf obo:OAE_0000001 . a rdfs:Class ; rdfs:label "mycophenolate mofetil [Chemical/Ingredient]" ; rdfs:subClassOf . obo:CIDO_0000339 a rdfs:Class ; rdfs:label "VQIDRLITGRLQSLQ"@en ; rdfs:subClassOf obo:CIDO_0000314 . obo:PR_O00555 a rdfs:Class ; rdfs:label "voltage-dependent P/Q-type calcium channel subunit alpha-1A (human)" ; rdfs:comment "A voltage-dependent P/Q-type calcium channel subunit alpha-1A that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000002118 , obo:PR_000029067 . obo:OBI_0000899 a rdfs:Class ; rdfs:label "organellar RNA extract" ; rdfs:comment "A RNA extract that is the output of an extraction process in which RNA molecules found in an organelle, e.g., mitochondrion, ER, or chloroplast, excluding the nucleus, are extracted." ; rdfs:subClassOf obo:OBI_0000880 . obo:NCBITaxon_255730 a rdfs:Class ; rdfs:label "SARS coronavirus Sino1-11" ; rdfs:subClassOf obo:NCBITaxon_694009 . obo:GO_0046718 a rdfs:Class ; rdfs:label "viral entry into host cell" ; rdfs:comment "The process that occurs after viral attachment by which a virus, or viral nucleic acid, breaches the plasma membrane or cell envelope and enters the host cell. The process ends when the viral nucleic acid is released into the host cell cytoplasm." ; rdfs:subClassOf obo:GO_0052126 . obo:PR_P57078 a rdfs:Class ; rdfs:label "receptor-interacting serine/threonine-protein kinase 4 (human)" ; rdfs:comment "A receptor-interacting serine/threonine-protein kinase 4 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000014025 , obo:PR_000029067 . obo:OAE_0000374 a rdfs:Class ; rdfs:label "pain AE" ; rdfs:comment "a sensory capability AE that has an outcome of pain in a patient" ; rdfs:subClassOf obo:OAE_0000582 . a rdfs:Class ; rdfs:label "A [Preparations]" ; rdfs:subClassOf . obo:PR_000001480 a rdfs:Class ; rdfs:label "low affinity immunoglobulin gamma Fc region receptor II-a" ; rdfs:comment "An immunoglobulin gamma Fc receptor II/III/IV that is a translation product of the human FCGR2A gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000001355 . obo:CIDO_0020032 a rdfs:Class ; rdfs:label "ASSURANCE SARS-COV-2 PANEL" ; rdfs:seeAlso ; rdfs:subClassOf obo:CIDO_0000454 . obo:GO_0009059 a rdfs:Class ; rdfs:label "macromolecule biosynthetic process" ; rdfs:comment "The chemical reactions and pathways resulting in the formation of a macromolecule, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass." ; rdfs:subClassOf obo:GO_0043170 , obo:GO_1901576 . obo:PR_000001099 a rdfs:Class ; rdfs:label "5-hydroxytryptamine receptor 2" ; rdfs:comment "A 5-hydroxytryptamine receptor that is a translation product of the human HTR2A, HTR2B, or HTR2C genes, 1:1 orthologs thereof, or a semi-ortholog thereof. The preferred ligand is 5-hydroxytryptamine (serotonin)." ; rdfs:subClassOf obo:PR_000044625 . obo:PR_000011521 a rdfs:Class ; rdfs:label "nuclear pore glycoprotein p62" ; rdfs:comment "A protein that is a translation product of the human NUP62 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:CHEBI_50340 a rdfs:Class ; rdfs:label "3-carbamimidamidopropyl group" ; rdfs:subClassOf obo:CHEBI_50325 . obo:GO_0015031 a rdfs:Class ; rdfs:label "protein transport" ; rdfs:comment "The directed movement of proteins into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." ; rdfs:subClassOf obo:GO_0045184 , obo:GO_0071702 , obo:GO_0071705 . obo:CHEBI_59769 a rdfs:Class ; rdfs:label "acetal" ; rdfs:comment "An organooxygen compound having the structure RR'C(OR'')(OR''') (R'', R''' =/= H). Mixed acetals have R'' and R''' groups which differ." ; rdfs:subClassOf obo:CHEBI_36963 . obo:DOID_0080711 a rdfs:Class ; rdfs:label "multisystem inflammatory syndrome in children"@en ; rdfs:comment "A Coronavirus infectious disease that is characterized by a patient aged less than 21 years with fever, laboratory evidence of inflammation, and evidence of clinically severe illness requiring hospitalization, with multisystem organ involvement (cardiovascular, dermatologic, gastrointestinal, hematologic, neurologic, renal, or respiratory) who tested positive for SARS-CoV-2 or had exposure to COVID-19." ; rdfs:subClassOf obo:DOID_0080599 . obo:PR_000050288 a rdfs:Class ; rdfs:label "2'-O-methyltransferase nsp16 (SARS-CoV-2)" ; rdfs:comment "An ORF1ab proteolytic cleavage product (SARS-CoV-2) that is the C-terminal portion produced by the enzymatic action of 3CL-PRO proteinase (nsp5) when it cleaves the precursor replicase polyprotein 1ab (SARS-CoV-2) between residues 6798-6799. UniProtKB:P0DTD1, 6453-6798." ; rdfs:subClassOf obo:PR_000050283 . obo:CIDO_0000481 a rdfs:Class ; rdfs:label "CKFAVCGDGFVPFLL" ; rdfs:comment "A coronavirus epitope that is part of some S protein from HCoV HKU1 composed of the following amino acids CKFAVCGDGFVPFLL" ; rdfs:subClassOf obo:CIDO_0000409 . obo:CIDO_0000988 a rdfs:Class ; rdfs:label "SARS-CoV2 orf8 protein binding to human CHPF" ; rdfs:comment "SARS-CoV2 orf8 protein binding to human CHPF, as evidented by an affinity-purification mass spectrometry experiment" ; rdfs:subClassOf obo:CIDO_0000051 . obo:CHEBI_52211 a rdfs:Class ; rdfs:label "physiological role" ; rdfs:subClassOf obo:CHEBI_24432 . obo:CHEBI_43799 a rdfs:Class ; rdfs:label "butan-1-amine" ; rdfs:comment "A primary aliphatic amine that is butane substituted by an amino group at position 1." ; rdfs:subClassOf obo:CHEBI_17062 . obo:CIDO_0020144 a rdfs:Class ; rdfs:label "FRL SARS CoV-2 Test" ; rdfs:seeAlso ; rdfs:subClassOf obo:CIDO_0000454 . a rdfs:Class ; rdfs:label "Hypersensitivity, Immediate [Disease/Finding]" ; rdfs:subClassOf . obo:CHEBI_39418 a rdfs:Class ; rdfs:label "straight-chain saturated fatty acid" ; rdfs:comment "Any saturated fatty acid lacking a side-chain." ; rdfs:subClassOf obo:CHEBI_26607 , obo:CHEBI_59202 . obo:NCBITaxon_2042571 a rdfs:Class ; rdfs:label "Coronavirus PREDICT CoV-45" ; rdfs:subClassOf obo:NCBITaxon_366617 . obo:VO_0000615 a rdfs:Class ; rdfs:label "vaccine role"@en ; rdfs:subClassOf obo:BFO_0000023 . obo:PR_Q12852 a rdfs:Class ; rdfs:label "mitogen-activated protein kinase kinase kinase 12 (human)" ; rdfs:comment "A mitogen-activated protein kinase kinase kinase 12 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000010131 , obo:PR_000029067 . obo:PR_Q92731 a rdfs:Class ; rdfs:label "estrogen receptor beta (human)" ; rdfs:comment "An estrogen receptor beta that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000007205 , obo:PR_000029067 . obo:GO_0043085 a rdfs:Class ; rdfs:label "positive regulation of catalytic activity" ; rdfs:comment "Any process that activates or increases the activity of an enzyme." ; rdfs:subClassOf obo:GO_0050790 , obo:GO_0065009 . obo:CIDO_0000648 a rdfs:Class ; rdfs:label "P1000L in SARS-CoV-2 pp1b protein" ; rdfs:comment "An AA mutation or AA variant that has mutated an amino acid at position 1000 into a leucine" ; rdfs:subClassOf obo:CIDO_0001084 . obo:PR_000007184 a rdfs:Class ; rdfs:label "endoplasmic reticulum metallopeptidase 1" ; rdfs:comment "A protein that is a translation product of the human ERMP1 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:NCBITaxon_2501420 a rdfs:Class ; rdfs:label "Yak coronavirus" ; rdfs:subClassOf obo:NCBITaxon_694003 . obo:CHEBI_35366 a rdfs:Class ; rdfs:label "fatty acid" ; rdfs:comment "Any aliphatic monocarboxylic acid derived from or contained in esterified form in an animal or vegetable fat, oil or wax. Natural fatty acids commonly have a chain of 4 to 28 carbons (usually unbranched and even-numbered), which may be saturated or unsaturated. By extension, the term is sometimes used to embrace all acyclic aliphatic carboxylic acids." ; rdfs:subClassOf obo:CHEBI_18059 , obo:CHEBI_25384 . obo:NCBITaxon_681870 a rdfs:Class ; rdfs:label "Kenya bat coronavirus BtKY24" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:OPMI_0000228 a rdfs:Class ; rdfs:label "physician specialty information"@en ; rdfs:subClassOf obo:IAO_0000030 . obo:OPMI_0000526 a rdfs:Class ; rdfs:label "primary diagnosis status"@en ; rdfs:comment "The primary diagnosis refers to the patient condition that demands the most provider resources during the patient’s stay." ; rdfs:subClassOf obo:OPMI_0000533 . obo:VO_0000562 a rdfs:Class ; rdfs:label "therapeutic vaccine function" ; rdfs:comment "The therapeutic vaccine function is a function realized by the process of vaccination and leading to induction of an adaptive immune response to the antigens in a vaccine, which ameliorates a specific disorder." ; rdfs:subClassOf obo:VO_0000278 . obo:CHEBI_29968 a rdfs:Class ; rdfs:label "D-lysine residue" ; rdfs:subClassOf obo:CHEBI_32568 . obo:GO_0022618 a rdfs:Class ; rdfs:label "ribonucleoprotein complex assembly" ; rdfs:comment "The aggregation, arrangement and bonding together of proteins and RNA molecules to form a ribonucleoprotein complex." ; rdfs:subClassOf obo:GO_0043933 , obo:GO_0065003 . obo:CHEBI_64176 a rdfs:Class ; rdfs:label "H3-receptor antagonist" ; rdfs:comment "A histamine antagonist that selectively binds to but does not activate histamine H3 receptors, thereby blocking the actions of endogenous histamine." ; rdfs:subClassOf obo:CHEBI_37956 . obo:PR_000015017 a rdfs:Class ; rdfs:label "mitochondrial 2-oxodicarboxylate carrier" ; rdfs:comment "A protein that is a translation product of the human SLC25A21 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:NCBITaxon_749427 a rdfs:Class ; rdfs:label "Glaucus-gull coronavirus PBA-173" ; rdfs:subClassOf obo:NCBITaxon_749416 . a rdfs:Class ; rdfs:label "Parkinsonian Disorders [Disease/Finding]" ; rdfs:subClassOf , . a rdfs:Class ; rdfs:label "Attention Deficit and Disruptive Behavior Disorders [Disease/Finding]" ; rdfs:subClassOf . obo:PR_P08183 a rdfs:Class ; rdfs:label "ATP-dependent translocase ABCB1 (human)" ; rdfs:comment "An ATP-dependent translocase ABCB1 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000001891 , obo:PR_000029067 . obo:OAE_0000624 a rdfs:Class ; rdfs:label "abnormal body temperature AE" ; rdfs:comment "a homeostasis AE whic has an outcome of abnomal body temperature, which is a deviation in the level of heat natural to a living being"@en ; rdfs:subClassOf obo:OAE_0000555 . obo:PR_000010154 a rdfs:Class ; rdfs:label "mitogen-activated protein kinase 13" ; rdfs:comment "A map kinase p38 that is a translation product of the human MAPK13 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000003106 . obo:HP_0032180 a rdfs:Class ; rdfs:label "Abnormal circulating metabolite concentration" ; rdfs:comment "An abnormal level of an analyte measured in the blood." ; rdfs:subClassOf obo:HP_0001939 . obo:CHEBI_65340 a rdfs:Class ; rdfs:label "5-formyltetrahydrofolate(2-)" ; rdfs:comment "A dicarboxylic acid dianion obtained by deprotonation of the carboxy groups of 5-formyltetrahydrofolic acid." ; rdfs:subClassOf obo:CHEBI_28965 . a rdfs:Class ; rdfs:label "Salicylanilides [Chemical/Ingredient]" ; rdfs:subClassOf , . obo:CIDO_0000060 a rdfs:Class ; rdfs:label "SARS-CoV-2 S protein interaction with host protein"@en ; rdfs:comment "A molecular interaction that has participant of the SARS-CoV-2 S protein and a host protein" ; rdfs:subClassOf obo:CIDO_0000348 . obo:PR_P08887 a rdfs:Class ; rdfs:label "interleukin-6 receptor subunit alpha (human)" ; rdfs:comment "An interleukin-6 receptor subunit alpha that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000001394 , obo:PR_000029067 . obo:VO_0000249 a rdfs:Class ; rdfs:label "vaccine-induced antiviral neutralizing antibody response" ; rdfs:subClassOf obo:VO_0000309 . obo:NCBITaxon_441977 a rdfs:Class ; rdfs:label "Chinese bamboo rat coronavirus Guangxi/B305/2005" ; rdfs:subClassOf obo:NCBITaxon_441985 . obo:CIDO_0020184 a rdfs:Class ; rdfs:label "LetsGetChecked Coronavirus (COVID-19) Test" ; rdfs:seeAlso ; rdfs:subClassOf obo:CIDO_0000454 . obo:NCBITaxon_903633 a rdfs:Class ; rdfs:label "Kenya bat coronavirus BtKY95" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:CHEBI_38749 a rdfs:Class ; rdfs:label "dihydroxyflavanone" ; rdfs:comment "Any hydroxyflavanone carrying two hydroxy substituents." ; rdfs:subClassOf obo:CHEBI_24697 . obo:PR_000011278 a rdfs:Class ; rdfs:label "NLR family member X1" ; rdfs:comment "A protein that is a translation product of the human NLRX1 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:CHEBI_71219 a rdfs:Class ; rdfs:label "pazopanib" ; rdfs:comment "A pyrimidine that is 5-(pyrimidin-2-yl}amino-2-methylbenzenesulfonamide substituted at position 4 by a (2,3-dimethylindazol-6-yl)(methyl)amino group. Used as its hydrochloride salt for treatment of kidney cancer." ; rdfs:subClassOf obo:CHEBI_35358 , obo:CHEBI_38338 , obo:CHEBI_38769 . obo:PR_000001812 a rdfs:Class ; rdfs:label "EGF receptor type tyrosine-protein kinase" ; rdfs:comment "A protein with core architecture consisting of a signal sequence, a Receptor L domain (Pfam:PF01030), a Furin-like cysteine rich region (Pfam:PF00757), another Receptor L domain, a transmembrane domain, and a Protein tyrosine kinase domain (Pfam:PF07714), that may be followed by up to two YLP motifs (Pfam:PF02757)." ; rdfs:subClassOf obo:PR_000000001 . obo:CHEBI_18254 a rdfs:Class ; rdfs:label "ribonucleoside" ; rdfs:comment "Any nucleoside where the sugar component is D-ribose." ; rdfs:subClassOf obo:CHEBI_33838 , obo:CHEBI_47019 . obo:CHEBI_46940 a rdfs:Class ; rdfs:label "indanes" ; rdfs:subClassOf obo:CHEBI_36785 . a rdfs:Class ; rdfs:label "Urinary Bladder Neck Obstruction [Disease/Finding]" ; rdfs:subClassOf , . obo:CHEBI_39317 a rdfs:Class ; rdfs:label "growth regulator" ; rdfs:comment "Any chemical substance that inhibits the life-cycle of an organism." ; rdfs:subClassOf obo:CHEBI_24432 . obo:PR_P06821 a rdfs:Class ; rdfs:label "matrix protein 2 (Influenza A virus (strain A/Puerto Rico/8/1934 H1N1))" ; rdfs:comment "An influenzavirus matrix protein 2 that is encoded in the genome of the H1N1 strain A/Puerto Rico/8/1934." ; rdfs:subClassOf obo:PR_000045385 , obo:PR_000049764 . obo:CHEBI_50221 a rdfs:Class ; rdfs:label "maleate salt" ; rdfs:comment "Salts from maleic acid." ; rdfs:subClassOf obo:CHEBI_24868 . obo:PR_P00742 a rdfs:Class ; rdfs:label "coagulation factor X (human)" ; rdfs:comment "A coagulation factor X that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000007294 , obo:PR_000029067 . obo:CIDO_0000108 a rdfs:Class ; rdfs:label "interruption to SARS-CoV replication in host cell"@en ; rdfs:comment "A process that interrupts SARS-CoV virus entry to host cell" ; rdfs:subClassOf obo:CIDO_0000103 . obo:CIDO_0001061 a rdfs:Class ; rdfs:label "SARS-CoV2 orf9c protein binding to human RETREG3" ; rdfs:comment "SARS-CoV2 orf9c protein binding to human RETREG3, as evidented by an affinity-purification mass spectrometry experiment" ; rdfs:subClassOf obo:CIDO_0000054 . obo:CHEBI_33697 a rdfs:Class ; rdfs:label "ribonucleic acid" ; rdfs:comment "High molecular weight, linear polymers, composed of nucleotides containing ribose and linked by phosphodiester bonds; RNA is central to the synthesis of proteins." ; rdfs:subClassOf obo:CHEBI_33696 . a rdfs:Class ; rdfs:label "Unknown Cellular or Molecular Interaction [MoA]" ; rdfs:subClassOf . obo:OPMI_0000497 a rdfs:Class ; rdfs:label "pharmacy visit"@en ; rdfs:comment "A visit to the pharmacy for dispensing of drug, at a care site, within one day" ; rdfs:subClassOf obo:OPMI_0000482 . obo:HP_0001063 a rdfs:Class ; rdfs:label "Acrocyanosis" ; rdfs:subClassOf obo:HP_0000961 . obo:PR_P62917 a rdfs:Class ; rdfs:label "60S ribosomal protein L8 (human)" ; rdfs:comment "A 60S ribosomal protein L8 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000014235 , obo:PR_000029067 . obo:PR_Q00536 a rdfs:Class ; rdfs:label "cyclin-dependent kinase 16 (human)" ; rdfs:comment "A cyclin-dependent kinase 16 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000012441 , obo:PR_000029067 . obo:NCBITaxon_1679891 a rdfs:Class ; rdfs:label "Coronavirus RCoV/D_RMU10_1972/Myo_gla/GER/2010" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:NCBITaxon_931909 a rdfs:Class ; rdfs:label "Alphacoronavirus Eptesicus fuscus/Appalachian Ridge/P1-5088/IT/USA/2009" ; rdfs:subClassOf obo:NCBITaxon_366617 . a rdfs:Class ; rdfs:label "Labyrinth Diseases [Disease/Finding]" ; rdfs:subClassOf . obo:CHEBI_64054 a rdfs:Class ; rdfs:label "delta-opioid receptor agonist" ; rdfs:subClassOf obo:CHEBI_60601 , obo:CHEBI_60606 . obo:PR_000001043 a rdfs:Class ; rdfs:label "Na(+)/H(+) exchange regulatory cofactor with ERM-binding domain" ; rdfs:comment "A protein that consists of two copies of the PDZ domain (Pfam:PF00595) and a copy of the EBP50, C-terminal (Pfam:PF09007) domain." ; rdfs:subClassOf obo:PR_000000001 . obo:NCBITaxon_2691598 a rdfs:Class ; rdfs:label "Hipposideros pomona bat coronavirus CHB25" ; rdfs:subClassOf obo:NCBITaxon_2691596 . obo:PR_Q86YB8 a rdfs:Class ; rdfs:label "ERO1-like protein beta (human)" ; rdfs:comment "An ERO1-like protein beta that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000007188 , obo:PR_000029067 . obo:NCBITaxon_1511621 a rdfs:Class ; rdfs:label "Coronavirus BtCoV/BS49/HUN/2013" ; rdfs:subClassOf obo:NCBITaxon_2664420 . a rdfs:Class ; rdfs:label "dasatinib [Chemical/Ingredient]" ; rdfs:subClassOf , . a rdfs:Class ; rdfs:label "Nucleic Acid Replication Alteration [PE]" ; rdfs:subClassOf . obo:CHEBI_5937 a rdfs:Class ; rdfs:label "Interferon alfa-2a" ; rdfs:subClassOf obo:CHEBI_50860 . obo:CIDO_0001121 a rdfs:Class ; rdfs:label "SARS-CoV2 orf8 protein binding to human LOX"@en ; rdfs:comment "SARS-CoV2 orf8 protein binding to human LOX, as evidented by an affinity-purification mass spectrometry experiment" ; rdfs:subClassOf obo:CIDO_0000051 . obo:GO_0050896 a rdfs:Class ; rdfs:label "response to stimulus" ; rdfs:comment "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus. The process begins with detection of the stimulus and ends with a change in state or activity or the cell or organism." ; rdfs:subClassOf obo:GO_0008150 . obo:CIDO_0020082 a rdfs:Class ; rdfs:label "cobas SARS-CoV-2 & Influenza A/B" ; rdfs:seeAlso ; rdfs:subClassOf obo:CIDO_0000454 . obo:HP_0025032 a rdfs:Class ; rdfs:label "Abnormality of digestive system physiology"@en ; rdfs:comment "A functional anomaly of the digestive system." ; rdfs:subClassOf obo:HP_0025031 . obo:GO_0007169 a rdfs:Class ; rdfs:label "transmembrane receptor protein tyrosine kinase signaling pathway" ; rdfs:comment "The series of molecular signals initiated by an extracellular ligand binding to a receptor on the surface of the target cell where the receptor possesses tyrosine kinase activity, and ending with the regulation of a downstream cellular process, e.g. transcription." ; rdfs:subClassOf obo:GO_0007166 . obo:CHEBI_27026 a rdfs:Class ; rdfs:label "toxin" ; rdfs:comment "Poisonous substance produced by a biological organism such as a microbe, animal or plant." ; rdfs:subClassOf obo:CHEBI_25212 , obo:CHEBI_64909 . a rdfs:Class ; rdfs:label "Cytidine [Chemical/Ingredient]" ; rdfs:subClassOf , . obo:CIDO_0000880 a rdfs:Class ; rdfs:label "SARS-CoV2 nsp4 protein binding to human TIMM10" ; rdfs:comment "SARS-CoV2 nsp4 protein binding to human TIMM10, as evidented by an affinity-purification mass spectrometry experiment" ; rdfs:subClassOf obo:CIDO_0000581 . obo:VO_0000273 a rdfs:Class ; rdfs:label "vaccine-induced T cell interferon-gamma production"@en ; rdfs:subClassOf obo:VO_0000593 . obo:CIDO_0001015 a rdfs:Class ; rdfs:label "AZD7442" ; rdfs:subClassOf obo:CHEBI_23367 . a rdfs:Class ; rdfs:label "Brain Diseases [Disease/Finding]" ; rdfs:subClassOf . a rdfs:Class ; rdfs:label "Musculoskeletal Activity Alteration [PE]" ; rdfs:subClassOf . obo:CHEBI_48433 a rdfs:Class ; rdfs:label "angiotensin" ; rdfs:subClassOf obo:CHEBI_25905 . obo:CIDO_0000158 a rdfs:Class ; rdfs:label "airborne transmission of SARS-CoV-2"@en ; rdfs:subClassOf obo:CIDO_0000156 . a rdfs:Class ; rdfs:label "Cholinergic Antagonists [MoA]" ; rdfs:subClassOf . obo:DOID_12217 a rdfs:Class ; rdfs:label "Lewy body dementia" ; rdfs:comment "A dementia that is characterized by the development of abnormal proteinaceous (alpha-synuclein) cytoplasmic inclusions, called Lewy bodies, throughout the brain that results in progressive decline in mental abilities." ; rdfs:subClassOf obo:DOID_1307 . obo:CIDO_0020256 a rdfs:Class ; rdfs:label "Quick SARS-CoV-2rRT-PCR Kit" ; rdfs:seeAlso ; rdfs:subClassOf obo:CIDO_0000454 . obo:UBERON_0001087 a rdfs:Class ; rdfs:label "pleural fluid" ; rdfs:comment "Transudate contained in the pleural cavity." ; rdfs:subClassOf obo:UBERON_0006314 . obo:HP_0006500 a rdfs:Class ; rdfs:label "Abnormality of lower limb epiphysis morphology" ; rdfs:comment "An anomaly of one or more epiphyses of one or both legs." ; rdfs:subClassOf obo:HP_0002814 , obo:HP_0006505 . a rdfs:Class ; rdfs:label "Hematological Cell Quantity Alteration [PE]" ; rdfs:subClassOf . obo:CHEBI_35230 a rdfs:Class ; rdfs:label "fossil fuel" ; rdfs:comment "A fuel such as coal, oil and natural gas which has formed over many years through the decomposition of deposited vegetation which was under extreme pressure of an overburden of earth." ; rdfs:subClassOf obo:CHEBI_33292 . obo:CIDO_0000305 a rdfs:Class ; rdfs:label "HCoV HKU1 epitope"@en ; rdfs:subClassOf obo:CIDO_0000300 . obo:CIDO_0001040 a rdfs:Class ; rdfs:label "SARS-CoV2 orf9b protein binding to human MARK3" ; rdfs:comment "SARS-CoV2 orf9b protein binding to human MARK3, as evidented by an affinity-purification mass spectrometry experiment" ; rdfs:subClassOf obo:CIDO_0000052 . obo:CHEBI_18946 a rdfs:Class ; rdfs:label "delta-lactone" ; rdfs:comment "A lactone having a six-membered lactone ring." ; rdfs:subClassOf obo:CHEBI_25000 . a rdfs:Class ; rdfs:label "Benzylidene Compounds [Chemical/Ingredient]" ; rdfs:subClassOf . obo:NCBITaxon_2501929 a rdfs:Class ; rdfs:label "NL63-related bat coronavirus strain BtKYNL63-9b" ; rdfs:subClassOf obo:NCBITaxon_2509512 . obo:PR_000014222 a rdfs:Class ; rdfs:label "60S ribosomal protein L37" ; rdfs:comment "A protein that is a translation product of the human RPL37 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:PR_000004439 a rdfs:Class ; rdfs:label "sodium/potassium-transporting ATPase subunit beta-1" ; rdfs:comment "A protein that is a translation product of the human ATP1B1 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:CHEBI_48560 a rdfs:Class ; rdfs:label "dopaminergic agent" ; rdfs:comment "A drug used for its effects on dopamine receptors, on the life cycle of dopamine, or on the survival of dopaminergic neurons." ; rdfs:subClassOf obo:CHEBI_35942 . obo:CIDO_0000598 a rdfs:Class ; rdfs:label "AA variant in SARS-CoV-2 E protein"@en ; rdfs:subClassOf obo:CIDO_0000237 . obo:CHEBI_135466 a rdfs:Class ; rdfs:label "nafamostat" ; rdfs:subClassOf obo:CHEBI_22723 , obo:CHEBI_24436 . obo:CHEBI_189676 a rdfs:Class ; rdfs:label "protease-activated receptor-2 antagonist" ; rdfs:comment "An antagonist at the protease-activated receptor-2." ; rdfs:subClassOf obo:CHEBI_48706 . obo:GO_0015276 a rdfs:Class ; rdfs:label "ligand-gated ion channel activity" ; rdfs:comment "Enables the transmembrane transfer of an ion by a channel that opens when a specific ligand has been bound by the channel complex or one of its constituent parts." ; rdfs:subClassOf obo:GO_0005216 , obo:GO_0022836 . obo:CIDO_0001072 a rdfs:Class ; rdfs:label "AA variant in SARS-CoV-2 nsp1 protein"@en ; rdfs:subClassOf obo:CIDO_0000714 . obo:GO_0051347 a rdfs:Class ; rdfs:label "positive regulation of transferase activity" ; rdfs:comment "Any process that activates or increases the frequency, rate or extent of transferase activity, the catalysis of the transfer of a group, e.g. a methyl group, glycosyl group, acyl group, phosphorus-containing, or other groups, from a donor compound to an acceptor." ; rdfs:subClassOf obo:GO_0043085 , obo:GO_0051338 . obo:NCBITaxon_389161 a rdfs:Class ; rdfs:label "Bat coronavirus (BtCoV/A912/2005)" ; rdfs:subClassOf obo:NCBITaxon_389126 . obo:CHEBI_32494 a rdfs:Class ; rdfs:label "D-phenylalaninate" ; rdfs:comment "The D-enantiomer of phenylalaninate." ; rdfs:subClassOf obo:CHEBI_32504 . obo:CHEBI_67079 a rdfs:Class ; rdfs:label "anti-inflammatory agent" ; rdfs:comment "Any compound that has anti-inflammatory effects." ; rdfs:subClassOf obo:CHEBI_33232 . obo:UBERON_0004120 a rdfs:Class ; rdfs:label "mesoderm-derived structure" ; rdfs:comment "An anatomical structure that develops (entirely or partially) from the mesoderm." ; rdfs:subClassOf obo:UBERON_0000061 . obo:CIDO_0001161 a rdfs:Class ; rdfs:label "AA variant in SARS-CoV-2 S protein S2 HR1 region"@en ; rdfs:subClassOf obo:CIDO_0000595 . obo:CHEBI_64947 a rdfs:Class ; rdfs:label "anti-HIV-1 agent" ; rdfs:comment "An anti-HIV agent that destroys or inhibits the replication of HIV-1, the more infective and more virulent of the two types of HIV virus." ; rdfs:subClassOf obo:CHEBI_64946 . obo:NCBITaxon_1288699 a rdfs:Class ; rdfs:label "Bat coronavirus POA/2012/E11" ; rdfs:subClassOf obo:NCBITaxon_366617 . obo:PR_000007510 a rdfs:Class ; rdfs:label "tyrosine-protein kinase Fgr" ; rdfs:comment "A proto-oncogene SRC-like tyrosine-protein kinase that is a translation product of the human FGR gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000002997 . obo:PR_000016876 a rdfs:Class ; rdfs:label "thymidylate synthase" ; rdfs:comment "A protein that is a translation product of the human TYMS gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:NCBITaxon_249071 a rdfs:Class ; rdfs:label "SARS coronavirus HSZ-Cb" ; rdfs:subClassOf obo:NCBITaxon_694009 . obo:GO_0051716 a rdfs:Class ; rdfs:label "cellular response to stimulus" ; rdfs:comment "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus. The process begins with detection of the stimulus by a cell and ends with a change in state or activity or the cell." ; rdfs:subClassOf obo:GO_0009987 , obo:GO_0050896 . obo:CIDO_0000247 a rdfs:Class ; rdfs:label "human SNP variant"@en ; rdfs:subClassOf obo:CHEBI_24431 . obo:CHEBI_38234 a rdfs:Class ; rdfs:label "DNA polymerase inhibitor" ; rdfs:comment "Any inhibitor of a DNA polymerase." ; rdfs:subClassOf obo:CHEBI_76815 . obo:GO_0036211 a rdfs:Class ; rdfs:label "protein modification process" ; rdfs:comment "The covalent alteration of one or more amino acids occurring in proteins, peptides and nascent polypeptides (co-translational, post-translational modifications). Includes the modification of charged tRNAs that are destined to occur in a protein (pre-translation modification)." ; rdfs:subClassOf obo:GO_0019538 , obo:GO_0043170 . obo:PR_000002351 a rdfs:Class ; rdfs:label "serine/threonine-protein kinase 26" ; rdfs:comment "A serine/threonine-protein kinase, MST4-like that is a translation product of the human STK26 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000002212 . a rdfs:Class ; rdfs:label "Malaria, Falciparum [Disease/Finding]" ; rdfs:subClassOf . obo:PR_000008630 a rdfs:Class ; rdfs:label "high mobility group protein B1" ; rdfs:comment "A protein that is a translation product of the human HMGB1 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:CHEBI_38101 a rdfs:Class ; rdfs:label "organonitrogen heterocyclic compound" ; rdfs:comment "Any organonitrogen compound containing a cyclic component with nitrogen and at least one other element as ring member atoms." ; rdfs:subClassOf obo:CHEBI_24532 , obo:CHEBI_35352 . a rdfs:Class ; rdfs:label "Pregnancy Complications [Disease/Finding]" ; rdfs:subClassOf . obo:CIDO_0000428 a rdfs:Class ; rdfs:label "SARS diagnosis conclusion"@en ; rdfs:comment "The representation of a conclusion of a diagnostic process for the SARS coronavirus disease." ; rdfs:subClassOf obo:CIDO_0000427 . obo:CHEBI_29016 a rdfs:Class ; rdfs:label "arginine" ; rdfs:comment "An alpha-amino acid that is glycine in which the alpha-is substituted by a 3-guanidinopropyl group." ; rdfs:subClassOf obo:CHEBI_24436 , obo:CHEBI_26167 , obo:CHEBI_33704 . obo:GO_0006793 a rdfs:Class ; rdfs:label "phosphorus metabolic process" ; rdfs:comment "The chemical reactions and pathways involving the nonmetallic element phosphorus or compounds that contain phosphorus, usually in the form of a phosphate group (PO4)." ; rdfs:subClassOf obo:GO_0044237 . obo:OBI_0000456 a rdfs:Class ; rdfs:label "material transformation objective"@en ; rdfs:comment "an objective specifiction that creates an specific output object from input materials."@en ; rdfs:subClassOf obo:IAO_0000005 . obo:CIDO_0000970 a rdfs:Class ; rdfs:label "SARS-CoV2 orf10 protein binding to human TIMM8B" ; rdfs:comment "SARS-CoV2 orf10 protein binding to human TIMM8B, as evidented by an affinity-purification mass spectrometry experiment" ; rdfs:subClassOf obo:CIDO_0000050 . obo:CIDO_0001008 a rdfs:Class ; rdfs:label "Tridecactide" ; rdfs:subClassOf obo:CHEBI_23367 . obo:GO_0002696 a rdfs:Class ; rdfs:label "positive regulation of leukocyte activation" ; rdfs:comment "Any process that activates or increases the frequency, rate, or extent of leukocyte activation." ; rdfs:subClassOf obo:GO_0002684 , obo:GO_0002694 , obo:GO_0050867 . obo:PR_Q04759 a rdfs:Class ; rdfs:label "protein kinase C theta type (human)" ; rdfs:comment "A protein kinase C theta type that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000002344 , obo:PR_000029067 . obo:NCBITaxon_2687253 a rdfs:Class ; rdfs:label "Vespadelus baverstocki alphacoronavirus" ; rdfs:subClassOf obo:NCBITaxon_366617 . obo:OBI_0002532 a rdfs:Class ; rdfs:label "esophagus mucosa specimen" ; rdfs:comment "A specimen that is derived from esophagus mucosa." ; rdfs:subClassOf obo:OBI_0001479 . a rdfs:Class ; rdfs:label "Paramyxoviridae Infections [Disease/Finding]" ; rdfs:subClassOf . obo:NCBITaxon_2042586 a rdfs:Class ; rdfs:label "Coronavirus PREDICT CoV-62" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:CHEBI_134730 a rdfs:Class ; rdfs:label "umifenovir" ; rdfs:subClassOf obo:CHEBI_46867 . obo:RO_0002597 a rdf:Property ; rdfs:label "capable of negatively regulating" ; rdfs:comment "Holds between c and p if and only if c is capable of some activity a, and a negatively regulates p." ; rdfs:range ; rdfs:subPropertyOf obo:RO_0002596 . obo:PR_000011398 a rdfs:Class ; rdfs:label "nuclear receptor subfamily 1 group I member 3" ; rdfs:comment "A protein that is a translation product of the human NR1I3 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:VO_0000593 a rdfs:Class ; rdfs:label "vaccine specific T cell cytokine production" ; rdfs:subClassOf obo:VO_0000106 . obo:DOID_2468 a rdfs:Class ; rdfs:label "psychotic disorder" ; rdfs:comment "A cognitive disorder that involves abnormal thinking and perceptions resulting in a disconnection with reality." ; rdfs:subClassOf obo:DOID_1561 . a rdfs:Class ; rdfs:label "Phenols [Chemical/Ingredient]" ; rdfs:subClassOf . obo:CHEBI_135632 a rdfs:Class ; rdfs:label "camostat" ; rdfs:comment "A benzoate ester resulting from the formal condensation of the carboxy group of 4-guanidinobenzoic acid with the hydroxy group of 2-(dimethylamino)-2-oxoethyl (4-hydroxyphenyl)acetate. It is a potent inhibitor of the human transmembrane protease serine 2 (TMPRSS2) and its mesylate salt is currently under investigation for its effectiveness in COVID-19 patients." ; rdfs:subClassOf obo:CHEBI_140326 , obo:CHEBI_24436 , obo:CHEBI_33308 , obo:CHEBI_36054 , obo:CHEBI_51307 . obo:CIDO_0000876 a rdfs:Class ; rdfs:label "SARS-CoV2 nsp4 protein binding to human ALG11" ; rdfs:comment "SARS-CoV2 nsp4 protein binding to human ALG11, as evidented by an affinity-purification mass spectrometry experiment" ; rdfs:subClassOf obo:CIDO_0000581 . obo:PR_O14874 a rdfs:Class ; rdfs:label "[3-methyl-2-oxobutanoate dehydrogenase [lipoamide]] kinase, mitochondrial (human)" ; rdfs:comment "A [3-methyl-2-oxobutanoate dehydrogenase [lipoamide]] kinase, mitochondrial that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000004688 , obo:PR_000029067 . a rdfs:Class ; rdfs:label "Amenorrhea [Disease/Finding]" ; rdfs:subClassOf . a rdfs:Class ; rdfs:label "Gram-Positive Bacterial Infections [Disease/Finding]" ; rdfs:subClassOf . obo:PR_000008245 a rdfs:Class ; rdfs:label "glutamate receptor ionotropic, NMDA 1" ; rdfs:comment "An ionotropic glutamate receptor protein that is a translation product of the human GRIN1 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000044666 . a rdfs:Class ; rdfs:label "Thiethylperazine Malate [Chemical/Ingredient]" ; rdfs:subClassOf . obo:CHEBI_26407 a rdfs:Class ; rdfs:label "pyrans" ; rdfs:subClassOf obo:CHEBI_25693 , obo:CHEBI_38104 . obo:GO_0045428 a rdfs:Class ; rdfs:label "regulation of nitric oxide biosynthetic process" ; rdfs:comment "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of nitric oxide." ; rdfs:subClassOf obo:GO_0031326 , obo:GO_0080164 . obo:CHEBI_75884 a rdfs:Class ; rdfs:label "N-acylindole" ; rdfs:comment "A carboxamide resulting from the formal condensation of a carboxylic acid with the nitrogen of an indole." ; rdfs:subClassOf obo:CHEBI_24828 , obo:CHEBI_37622 . obo:NCBITaxon_1699325 a rdfs:Class ; rdfs:label "Myotis Bat Alphacoronavirus strain YNXY_15C" ; rdfs:subClassOf obo:NCBITaxon_366617 . obo:CHEBI_36786 a rdfs:Class ; rdfs:label "tetralins" ; rdfs:comment "Compounds containing a tetralin skeleton." ; rdfs:subClassOf obo:CHEBI_33836 , obo:CHEBI_36785 . obo:PR_Q92552 a rdfs:Class ; rdfs:label "28S ribosomal protein S27, mitochondrial (human)" ; rdfs:comment "A 28S ribosomal protein S27, mitochondrial that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000010635 , obo:PR_000029067 . obo:CHEBI_76206 a rdfs:Class ; rdfs:label "xenobiotic metabolite" ; rdfs:comment "Any metabolite produced by metabolism of a xenobiotic compound." ; rdfs:subClassOf obo:CHEBI_25212 . obo:OPMI_0000567 a rdfs:Class ; rdfs:label "drug exposure end date"@en ; rdfs:comment "The date on which a drug exposure ends for a patient." ; rdfs:subClassOf obo:OPMI_0000564 . obo:VO_0001744 a rdfs:Class ; rdfs:label "Canine Coronavirus Killed Virus Vaccine (USDA: 14P5.21)" ; rdfs:subClassOf obo:VO_0000932 . obo:PR_000007133 a rdfs:Class ; rdfs:label "ephrin type-B receptor 6" ; rdfs:comment "An ephrin receptor that is a translation product of the human EPHB6 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000025845 . obo:OBI_0600005 a rdfs:Class ; rdfs:label "collecting specimen from organism"@en ; rdfs:comment "a process with the objective to obtain a material entity that was part of an organism for potential future use in an investigation"@en ; rdfs:subClassOf obo:OBI_0000659 . obo:HP_0002239 a rdfs:Class ; rdfs:label "Gastrointestinal hemorrhage" ; rdfs:comment "Hemorrhage affecting the gastrointestinal tract." ; rdfs:subClassOf obo:HP_0011029 , obo:HP_0012719 . obo:OBI_0002547 a rdfs:Class ; rdfs:label "minor salivary gland specimen" ; rdfs:comment "A specimen that is derived from minor salivary gland." ; rdfs:subClassOf obo:OBI_0001479 . obo:CHEBI_33570 a rdfs:Class ; rdfs:label "benzenediols" ; rdfs:subClassOf obo:CHEBI_33853 . obo:PR_000014203 a rdfs:Class ; rdfs:label "60S ribosomal protein L23" ; rdfs:comment "A protein that is a translation product of the human RPL23 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:DRON_00017641 a rdfs:Class ; rdfs:label "Dipyrone" ; rdfs:subClassOf obo:OBI_0000047 . obo:NCBITaxon_389237 a rdfs:Class ; rdfs:label "Bat coronavirus (BtCoV/355A/2005)" ; rdfs:subClassOf obo:NCBITaxon_389126 . obo:NCBITaxon_756643 a rdfs:Class ; rdfs:label "Bovine coronavirus cow/WDBR-887/BRA/2003" ; rdfs:subClassOf obo:NCBITaxon_11128 . obo:PR_Q92995 a rdfs:Class ; rdfs:label "ubiquitin carboxyl-terminal hydrolase 13 (human)" ; rdfs:comment "A ubiquitin carboxyl-terminal hydrolase 13 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000017149 , obo:PR_000029067 . obo:PR_000000024 a rdfs:Class ; rdfs:label "Rho-associated protein kinase" ; rdfs:comment "A protein that is a translation product of an evolutionary-related gene with core domain composition consisting of an N-terminal Protein kinase domain (Pfam:PF00069), a Rho Binding domain (Pfam:PF08912), and a PH domain (Pfam:PF00169) and a Phorbol esters/diacylglycerol binding domain (C1 domain) (Pfam:PF00130) at the C-terminus. Rho-associated protein kinases are mediators of many cellular processes by being effectors of the small GTP-binding protein Rho." ; rdfs:subClassOf obo:PR_000000001 . obo:HP_0011696 a rdfs:Class ; rdfs:label "Supraventricular tachycardia with a manifest accessory pathway on the left free wall" ; rdfs:subClassOf obo:HP_0011694 . a rdfs:Class ; rdfs:label "famciclovir [Chemical/Ingredient]" ; rdfs:subClassOf . obo:CIDO_0000059 a rdfs:Class ; rdfs:label "SARS-CoV-2 Nsp14 protein interaction with host protein"@en ; rdfs:comment "A molecular interaction that has participant of the SARS-CoV-2 Nsp14 protein and a host protein" ; rdfs:subClassOf obo:CIDO_0000348 . obo:NCBITaxon_1235419 a rdfs:Class ; rdfs:label "Alphacoronavirus Eptesicus fuscus" ; rdfs:subClassOf obo:NCBITaxon_366617 . obo:PR_Q13164 a rdfs:Class ; rdfs:label "mitogen-activated protein kinase 7 (human)" ; rdfs:comment "A mitogen-activated protein kinase 7 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000010159 , obo:PR_000029067 . obo:CHEBI_49323 a rdfs:Class ; rdfs:label "contraceptive drug" ; rdfs:comment "A chemical substance that prevents or reduces the probability of conception." ; rdfs:subClassOf obo:CHEBI_50689 . obo:PR_000029896 a rdfs:Class ; rdfs:label "death-associated protein kinase" ; rdfs:comment "A protein that is a translation product of the human DAPK1, DAPK2, or DAPK3 genes, 1:1 orthologs thereof, or a semi-ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:NCBITaxon_1697926 a rdfs:Class ; rdfs:label "Deltacoronavirus B04" ; rdfs:subClassOf obo:NCBITaxon_1232736 . obo:NCBITaxon_1679883 a rdfs:Class ; rdfs:label "Coronavirus RCoV/D_RMU10_1055/Myo_gla/GER/2010" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:CIDO_0000900 a rdfs:Class ; rdfs:label "SARS-CoV2 nsp7 protein binding to human GNG5" ; rdfs:comment "SARS-CoV2 nsp7 protein binding to human GNG5, as evidented by an affinity-purification mass spectrometry experiment" ; rdfs:subClassOf obo:CIDO_0000049 . obo:NCBITaxon_1283333 a rdfs:Class ; rdfs:label "Bat coronavirus Cp/Yunnan2011" ; rdfs:subClassOf obo:NCBITaxon_694009 . obo:CIDO_0020178 a rdfs:Class ; rdfs:label "Kaira 2019-nCoV Detection Kit" ; rdfs:seeAlso ; rdfs:subClassOf obo:CIDO_0000454 . obo:NCBITaxon_1008261 a rdfs:Class ; rdfs:label "Helictidinae" ; rdfs:subClassOf obo:NCBITaxon_9655 . obo:NCBITaxon_1897072 a rdfs:Class ; rdfs:label "Bat coronavirus Car.per/1599/BRA/2012" ; rdfs:subClassOf obo:NCBITaxon_366617 . obo:CHEBI_4470 a rdfs:Class ; rdfs:label "dextromethorphan" ; rdfs:comment "A 6-methoxy-11-methyl-1,3,4,9,10,10a-hexahydro-2H-10,4a-(epiminoethano)phenanthrene in which the sterocenters at positions 4a, 10 and 10a have S-configuration. It is a prodrug of dextrorphan and used as an antitussive drug for suppressing cough." ; rdfs:subClassOf obo:CHEBI_146178 . obo:CHEBI_136622 a rdfs:Class ; rdfs:label "aci-nitro compound" ; rdfs:comment "Organonitrogen compounds that have the general structure R(1)(R(2))C=N(O)OH (R(1),R(2) = H, organyl). They are tautomers of C-nitro compounds." ; rdfs:subClassOf obo:CHEBI_35352 . a rdfs:Class ; rdfs:label "Steroid Receptor Modulators [MoA]" ; rdfs:subClassOf . a rdfs:Class ; rdfs:label "Onchocerciasis [Disease/Finding]" ; rdfs:subClassOf , . obo:CIDO_0020006 a rdfs:Class ; rdfs:label "ACON SARS-CoV-2 IgG/IgM Rapid Test" ; rdfs:seeAlso ; rdfs:subClassOf obo:CIDO_0000454 . obo:PR_000010155 a rdfs:Class ; rdfs:label "mitogen-activated protein kinase 15" ; rdfs:comment "A protein that is a translation product of the human MAPK15 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:PR_Q96RR4 a rdfs:Class ; rdfs:label "calcium/calmodulin-dependent protein kinase kinase 2 (human)" ; rdfs:comment "A calcium/calmodulin-dependent protein kinase kinase 2 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000004995 , obo:PR_000029067 . obo:CHEBI_38164 a rdfs:Class ; rdfs:label "organic heteropentacyclic compound" ; rdfs:subClassOf obo:CHEBI_38166 . obo:NCBITaxon_389143 a rdfs:Class ; rdfs:label "Bat coronavirus (BtCoV/A634/2005)" ; rdfs:subClassOf obo:NCBITaxon_389126 . obo:IDO_0000601 a rdfs:Class ; rdfs:label "host coming into contact with vector of infectious agent"@en ; rdfs:comment "A host exposure to environment with infectious agent where the environment contains an infectious agent vector."@en ; rdfs:subClassOf obo:IDO_0000597 . obo:OBI_0000025 a rdfs:Class ; rdfs:label "reference substance role"@en ; rdfs:comment "a role inhering in a material entity that is realized when characteristics or responses elicited by the substance are used for comparison or reference."@en ; rdfs:subClassOf obo:BFO_0000023 . obo:NCBITaxon_2042698 a rdfs:Class ; rdfs:label "SARS-related betacoronavirus Rp3/2004" ; rdfs:subClassOf obo:NCBITaxon_694009 . obo:OBI_0000257 a rdfs:Class ; rdfs:label "DNA extraction"@en ; rdfs:comment "A DNA extraction is a nucleic acid extraction where the desired output material is DNA."@en ; rdfs:subClassOf obo:OBI_0666667 . obo:NCBITaxon_231425 a rdfs:Class ; rdfs:label "Avian infectious bronchitis virus (strain H52)" ; rdfs:subClassOf obo:NCBITaxon_11120 . obo:NCBITaxon_931897 a rdfs:Class ; rdfs:label "Alphacoronavirus Eptesicus fuscus/Appalachian Ridge/P1-replicase/IT/USA/2009" ; rdfs:subClassOf obo:NCBITaxon_366617 . obo:HP_0001907 a rdfs:Class ; rdfs:label "Thromboembolism" ; rdfs:comment "The formation of a blood clot inside a blood vessel that subsequently travels through the blood stream from the site where it formed to another location in the body, generally leading to vascular occlusion at the distant site." ; rdfs:subClassOf obo:HP_0001977 . obo:DOID_0070093 a rdfs:Class ; rdfs:label "schizophrenia 18" ; rdfs:comment "A schizophrenia that has_material_basis_in a mutation of SLC1A1 on chromosome 9p24.2." ; rdfs:subClassOf obo:DOID_0050177 , obo:DOID_5419 . obo:NCBITaxon_239758 a rdfs:Class ; rdfs:label "SARS coronavirus Taiwan TC3" ; rdfs:subClassOf obo:NCBITaxon_694009 . obo:CIDO_0000316 a rdfs:Class ; rdfs:label "CEFQFCNDPFLGVYY"@en ; rdfs:subClassOf obo:CIDO_0000314 . obo:CIDO_0000887 a rdfs:Class ; rdfs:label "SARS-CoV2 nsp6 protein binding to human ATP13A3" ; rdfs:comment "SARS-CoV2 nsp6 protein binding to human ATP13A3, as evidented by an affinity-purification mass spectrometry experiment" ; rdfs:subClassOf obo:CIDO_0000048 . obo:PR_O95835 a rdfs:Class ; rdfs:label "serine/threonine-protein kinase LATS1 (human)" ; rdfs:comment "A serine/threonine-protein kinase LATS1 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000009686 , obo:PR_000029067 . obo:CHEBI_134249 a rdfs:Class ; rdfs:label "alkanesulfonate oxoanion" ; rdfs:comment "An alkanesulfonate in which the carbon at position 1 is attached to R, which can represent hydrogens, a carbon chain, or other groups." ; rdfs:subClassOf obo:CHEBI_33554 . obo:CHEBI_76779 a rdfs:Class ; rdfs:label "EC 3.4.21.26 (prolyl oligopeptidase) inhibitor" ; rdfs:comment "Any EC 3.4.21.* (serine endopeptidase) inhibitor that interferes with the action of prolyl oligopeptidase (EC 3.4.21.26)." ; rdfs:subClassOf obo:CHEBI_5924 . obo:DRON_00025187 a rdfs:Class ; rdfs:label "Ribavirin Injectable Solution" ; rdfs:subClassOf obo:DRON_00000020 . a rdfs:Class ; rdfs:label "Respiratory Hypersensitivity [Disease/Finding]" ; rdfs:subClassOf , . obo:OGG_20010239 a rdfs:Class ; rdfs:label "gene of Viruses" ; rdfs:comment "A gene of an organism of Viruses" ; rdfs:subClassOf obo:OGG_0000000002 . obo:DOID_0070077 a rdfs:Class ; rdfs:label "schizophrenia 1" ; rdfs:comment "A schizophrenia that has_material_basis_in an autosomal dominant mutation of SCZD1 on chromosome 5q23-q35." ; rdfs:subClassOf obo:DOID_0050736 , obo:DOID_5419 . a rdfs:Class ; rdfs:label "Heart Defects, Congenital [Disease/Finding]" ; rdfs:subClassOf , . obo:PR_P38435 a rdfs:Class ; rdfs:label "vitamin K-dependent gamma-carboxylase (human)" ; rdfs:comment "A vitamin K-dependent gamma-carboxylase that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000007956 , obo:PR_000029067 . obo:CIDO_0001212 a rdfs:Class ; rdfs:label "Multiple Real-Time PCR Kit for Detection of 2019-nCoV. (Coyote Bioscience Yixing Co., Ltd.)" ; rdfs:comment "Scope of application/Intended use: This kit is used for in vitro qualitative detection of novel coronavirus (2019-nCoV) in pharyngeal swabs and sputum samples of suspected cases of novel coronavirus infection pneumonia, patients with suspected cluster cases, and other patients who need to be diagnosed or differentially diagnosed with novel coronavirus infection. ) ORF1ab and N genes." ; rdfs:subClassOf obo:CIDO_0000021 . a rdfs:Class ; rdfs:label "Loperamide [Chemical/Ingredient]" ; rdfs:subClassOf . obo:PR_Q9BZQ6 a rdfs:Class ; rdfs:label "ER degradation-enhancing alpha-mannosidase-like protein 3 (human)" ; rdfs:comment "An ER degradation-enhancing alpha-mannosidase-like protein 3 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000006894 , obo:PR_000029067 . obo:CHEBI_2580 a rdfs:Class ; rdfs:label "unsaturated fatty acid anion" ; rdfs:comment "Any fatty acid anion containing at least one C-C unsaturated bond; formed by deprotonation of the carboxylic acid moiety." ; rdfs:subClassOf obo:CHEBI_28868 . obo:CIDO_0000911 a rdfs:Class ; rdfs:label "SARS-CoV2 nsp7 protein binding to human RAB18" ; rdfs:comment "SARS-CoV2 nsp7 protein binding to human RAB18, as evidented by an affinity-purification mass spectrometry experiment" ; rdfs:subClassOf obo:CIDO_0000049 . obo:GO_0006629 a rdfs:Class ; rdfs:label "lipid metabolic process" ; rdfs:comment "The chemical reactions and pathways involving lipids, compounds soluble in an organic solvent but not, or sparingly, in an aqueous solvent. Includes fatty acids; neutral fats, other fatty-acid esters, and soaps; long-chain (fatty) alcohols and waxes; sphingoids and other long-chain bases; glycolipids, phospholipids and sphingolipids; and carotenes, polyprenols, sterols, terpenes and other isoprenoids." ; rdfs:subClassOf obo:GO_0044238 , obo:GO_0071704 . obo:CHEBI_67239 a rdfs:Class ; rdfs:label "EC 3.2.1.20 (alpha-glucosidase) inhibitor" ; rdfs:comment "An EC 3.2.1.* (glycosidase) inhibitor that interferes with the action of alpha-glucosidase (EC 3.2.1.20)." ; rdfs:subClassOf obo:CHEBI_52424 . obo:PR_000017100 a rdfs:Class ; rdfs:label "SUN domain-containing protein 2" ; rdfs:comment "A protein that is a translation product of the human SUN2 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:CHEBI_34892 a rdfs:Class ; rdfs:label "nocodazole" ; rdfs:comment "A member of the class of benzimidazoles that is benzimidalole which is substituted at position 2 by a (methoxycarbonyl)amino group and at position 5 by a 2-thienoyl group. It is an antineoplastic agent that exerts its effect by depolymerising microtubules." ; rdfs:subClassOf obo:CHEBI_22715 , obo:CHEBI_23003 , obo:CHEBI_26961 , obo:CHEBI_76224 . obo:PR_000012242 a rdfs:Class ; rdfs:label "serine/threonine-protein kinase PAK 3" ; rdfs:comment "A protein that is a translation product of the human PAK3 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:HP_0006562 a rdfs:Class ; rdfs:label "Viral hepatitis" ; rdfs:comment "Inflammation of the liver due to infection with a virus." ; rdfs:subClassOf obo:HP_0012115 . obo:CIDO_0001087 a rdfs:Class ; rdfs:label "at-home over-the-counter COVID-19 diagnostic assay"@en ; rdfs:comment "at-home OTC COVID-19 diagnostic assay" ; rdfs:subClassOf obo:CIDO_0000258 . obo:PR_000044660 a rdfs:Class ; rdfs:label "voltage-gated sodium channel protein" ; rdfs:comment "A voltage-gated ion channel protein that has voltage-gated sodium channel activity. A voltage-gated sodium channel enables the transmembrane transfer of a sodium ion by a voltage-gated channel. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded." ; rdfs:subClassOf obo:PR_000044628 . obo:CIDO_0020025 a rdfs:Class ; rdfs:label "Anti-SARS-CoV-2 Rapid Test" ; rdfs:seeAlso ; rdfs:subClassOf obo:CIDO_0000454 . obo:NCBITaxon_643400 a rdfs:Class ; rdfs:label "Coronavirus Anas/p42/2005/GBR" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:CHEBI_24698 a rdfs:Class ; rdfs:label "hydroxyflavone" ; rdfs:comment "Any flavone in which one or more ring hydrogens are replaced by hydroxy groups." ; rdfs:subClassOf obo:CHEBI_24043 , obo:CHEBI_33822 . obo:DOID_10685 a rdfs:Class ; rdfs:label "separation anxiety disorder" ; rdfs:comment "An anxiety disorder that involves the feeling of excessive and inappropriate levels of anxiety over being separated from a person to whom the individual has a strong emotional attachment or place." ; rdfs:subClassOf obo:DOID_2030 . obo:CHEBI_28300 a rdfs:Class ; rdfs:label "glutamine" ; rdfs:comment "An alpha-amino acid that consists of butyric acid bearing an amino substituent at position 2 and a carbamoyl substituent at position 4." ; rdfs:subClassOf obo:CHEBI_26167 , obo:CHEBI_33704 . obo:CHEBI_76764 a rdfs:Class ; rdfs:label "EC 3.5.* (hydrolases acting on non-peptide C-N bonds) inhibitor" ; rdfs:comment "Any hydrolase inhibitor that interferes with the action of a hydrolase acting on C-N bonds, other than peptide bonds (EC 3.5.*.*)." ; rdfs:subClassOf obo:CHEBI_76759 . obo:NCBITaxon_864618 a rdfs:Class ; rdfs:label "Bat coronavirus BR98-55/BGR/2008" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:NCBITaxon_264373 a rdfs:Class ; rdfs:label "SARS coronavirus TW-HP3" ; rdfs:subClassOf obo:NCBITaxon_264370 . obo:NCBITaxon_243925 a rdfs:Class ; rdfs:label "SARS coronavirus HPZ-2003" ; rdfs:subClassOf obo:NCBITaxon_694009 . obo:CHEBI_59698 a rdfs:Class ; rdfs:label "phosphoric acids" ; rdfs:comment "Compounds containing one or more phosphoric acid units." ; rdfs:subClassOf obo:CHEBI_33457 . obo:GO_0051209 a rdfs:Class ; rdfs:label "release of sequestered calcium ion into cytosol" ; rdfs:comment "The process in which calcium ions sequestered in the endoplasmic reticulum, Golgi apparatus or mitochondria are released into the cytosolic compartment." ; rdfs:subClassOf obo:GO_0051283 , obo:GO_0070588 . obo:CHEBI_23888 a rdfs:Class ; rdfs:label "drug" ; rdfs:comment "Any substance which when absorbed into a living organism may modify one or more of its functions. The term is generally accepted for a substance taken for a therapeutic purpose, but is also commonly used for abused substances." ; rdfs:subClassOf obo:CHEBI_52217 . obo:CHEBI_145798 a rdfs:Class ; rdfs:label "ouabain(1-)" ; rdfs:comment "An organic anion that is the conjugate base of ouabain resulting from the deprotonation of the furanone moiety; major species at pH 7.3." ; rdfs:subClassOf obo:CHEBI_25696 . obo:PR_000012042 a rdfs:Class ; rdfs:label "protein OS-9" ; rdfs:comment "A protein that is a translation product of the human OS9 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:PR_O14745 a rdfs:Class ; rdfs:label "Na(+)/H(+) exchange regulatory cofactor NHE-RF1 (human)" ; rdfs:comment "A Na(+)/H(+) exchange regulatory cofactor NHE-RF1 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000001041 , obo:PR_000029067 . obo:CHEBI_37577 a rdfs:Class ; rdfs:label "heteroatomic molecular entity" ; rdfs:comment "A molecular entity consisting of two or more chemical elements." ; rdfs:subClassOf obo:CHEBI_36357 . a rdfs:Class ; rdfs:label "Tamoxifen [Chemical/Ingredient]" ; rdfs:subClassOf . obo:HP_0004408 a rdfs:Class ; rdfs:label "Abnormality of the sense of smell" ; rdfs:comment "An anomaly in the ability to perceive and distinguish scents (odors)." ; rdfs:subClassOf obo:HP_0000366 , obo:HP_0012638 . obo:PR_000018931 a rdfs:Class ; rdfs:label "angiotensinogen, signal peptide removed form" ; rdfs:comment "An angiotensinogen that has had the signal peptide removed." ; rdfs:subClassOf obo:PR_000003847 . a rdfs:Class ; rdfs:label "Sarcoma, Kaposi [Disease/Finding]" ; rdfs:subClassOf , , . obo:CHEBI_27093 a rdfs:Class ; rdfs:label "tricarboxylic acid" ; rdfs:comment "An oxoacid containing three carboxy groups." ; rdfs:subClassOf obo:CHEBI_33575 . a rdfs:Class ; rdfs:label "Ileal Diseases [Disease/Finding]" ; rdfs:subClassOf . obo:CHEBI_50629 a rdfs:Class ; rdfs:label "cyclooxygenase 2 inhibitor" ; rdfs:comment "A cyclooxygenase inhibitor that interferes with the action of cyclooxygenase 2." ; rdfs:subClassOf obo:CHEBI_35544 . obo:CHEBI_82699 a rdfs:Class ; rdfs:label "oritavancin" ; rdfs:comment "A semisynthetic glycopeptide used (as its bisphosphate salt) for the treatment of acute bacterial skin and skin structure infections caused or suspected to be caused by susceptible isolates of designated Gram-positive microorganisms including MRSA." ; rdfs:subClassOf obo:CHEBI_24396 , obo:CHEBI_63353 , obo:CHEBI_72588 . a rdfs:Class ; rdfs:label "Cycloheximide [Chemical/Ingredient]" ; rdfs:subClassOf . obo:CHEBI_189654 a rdfs:Class ; rdfs:label "4E2RCat" ; rdfs:subClassOf obo:CHEBI_50860 . obo:OBI_0000652 a rdfs:Class ; rdfs:label "material combination" ; rdfs:comment "is a material processing with the objective to combine two or more material entities as input into a single material entity as output." ; rdfs:subClassOf obo:OBI_0000094 . obo:DRON_00012220 a rdfs:Class ; rdfs:label "Thiothixene" ; rdfs:subClassOf obo:OBI_0000047 . obo:PR_P35590 a rdfs:Class ; rdfs:label "tyrosine-protein kinase receptor Tie-1 (human)" ; rdfs:comment "A tyrosine-protein kinase receptor Tie-1 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000016330 , obo:PR_000029067 . obo:NCBITaxon_681882 a rdfs:Class ; rdfs:label "Kenya bat coronavirus BtKY39" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:CIDO_0020155 a rdfs:Class ; rdfs:label "GetMyDNA COVID-19 Test Home Collection Kit" ; rdfs:seeAlso ; rdfs:subClassOf obo:CIDO_0000455 . obo:CIDO_0000007 a rdfs:Class ; rdfs:label "Human coronavirus NL63 disease process"@en ; rdfs:subClassOf obo:CIDO_0000001 . obo:CHEBI_46853 a rdfs:Class ; rdfs:label "piperazinecarboxamide" ; rdfs:subClassOf obo:CHEBI_26144 , obo:CHEBI_29347 . obo:NCBITaxon_2042560 a rdfs:Class ; rdfs:label "Coronavirus PREDICT CoV-35" ; rdfs:subClassOf obo:NCBITaxon_366617 . obo:CHEBI_32631 a rdfs:Class ; rdfs:label "L-methioninate" ; rdfs:comment "The L-enantiomer of methioninate." ; rdfs:subClassOf obo:CHEBI_32644 . obo:NCBITaxon_240551 a rdfs:Class ; rdfs:label "SARS coronavirus TWK" ; rdfs:subClassOf obo:NCBITaxon_694009 . obo:PR_000003895 a rdfs:Class ; rdfs:label "A-kinase anchor protein 8-like" ; rdfs:comment "A protein that is a translation product of the human AKAP8L gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . a rdfs:Class ; rdfs:label "Nodal Depolarization [PE]" ; rdfs:subClassOf . obo:NCBITaxon_2605444 a rdfs:Class ; rdfs:label "Gull coronavirus" ; rdfs:subClassOf obo:NCBITaxon_1986197 . obo:VO_0005159 a rdfs:Class ; rdfs:label "Ad26.COV2.S" ; rdfs:comment "A SARS-CoV-2 recombinant viral vector vaccine composed of Ad26 vector expressing S protein." ; rdfs:subClassOf obo:VO_0005268 . obo:PR_Q16584 a rdfs:Class ; rdfs:label "mitogen-activated protein kinase kinase kinase 11 (human)" ; rdfs:comment "A mitogen-activated protein kinase kinase kinase 11 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000010130 , obo:PR_000029067 . obo:PR_000005951 a rdfs:Class ; rdfs:label "casein kinase II subunit alpha'" ; rdfs:comment "A protein that is a translation product of the human CSNK2A2 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:CIDO_0000497 a rdfs:Class ; rdfs:label "FEVEKGVTVDDFVAV" ; rdfs:comment "A coronavirus epitope that is part of some S protein from HCoV HKU1 composed of the following amino acids FEVEKGVTVDDFVAV" ; rdfs:subClassOf obo:CIDO_0000450 . obo:OBI_0002542 a rdfs:Class ; rdfs:label "aorta specimen" ; rdfs:comment "A specimen that is derived from aorta." ; rdfs:subClassOf obo:OBI_0001479 . obo:GO_0065007 a rdfs:Class ; rdfs:label "biological regulation" ; rdfs:comment "Any process that modulates a measurable attribute of any biological process, quality or function." ; rdfs:subClassOf obo:GO_0008150 . obo:CIDO_0000842 a rdfs:Class ; rdfs:label "SARS-CoV2 nsp13 protein binding to human GOLGB1" ; rdfs:comment "SARS-CoV2 nsp13 protein binding to human GOLGB1, as evidented by an affinity-purification mass spectrometry experiment" ; rdfs:subClassOf obo:CIDO_0000058 . obo:CHEBI_49662 a rdfs:Class ; rdfs:label "indometacin" ; rdfs:comment "A member of the class of indole-3-acetic acids that is indole-3-acetic acid in which the indole ring is substituted at positions 1, 2 and 5 by p-chlorobenzoyl, methyl, and methoxy groups, respectively. A non-steroidal anti-inflammatory drug, it is used in the treatment of musculoskeletal and joint disorders including osteoarthritis, rheumatoid arthritis, gout, bursitis and tendinitis." ; rdfs:subClassOf obo:CHEBI_24803 , obo:CHEBI_35618 , obo:CHEBI_75884 , obo:CHEBI_83403 . obo:PR_P09603 a rdfs:Class ; rdfs:label "macrophage colony-stimulating factor 1 (human)" ; rdfs:comment "A macrophage colony-stimulating factor 1 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000005930 , obo:PR_000029067 . obo:PR_000003284 a rdfs:Class ; rdfs:label "dual specificity mitogen-activated protein kinase kinase 3" ; rdfs:comment "A dual specificity mitogen-activated protein kinase kinase 3/6 that is a translation product of the human MAP2K3 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000021990 . obo:PR_000016125 a rdfs:Class ; rdfs:label "tubulin-specific chaperone A" ; rdfs:comment "A protein that is a translation product of the human TBCA gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:CHEBI_50312 a rdfs:Class ; rdfs:label "onium compound" ; rdfs:subClassOf obo:CHEBI_37577 . obo:CIDO_0001033 a rdfs:Class ; rdfs:label "Carrimycin" ; rdfs:subClassOf obo:CHEBI_23367 . obo:HP_0031861 a rdfs:Class ; rdfs:label "Decreased heart rate variability" ; rdfs:comment "Reduced variation of beat-to-beat intervals of the heart that occurs in conjunction with the respiratory cycle." ; rdfs:subClassOf obo:HP_0031860 . obo:GO_0032879 a rdfs:Class ; rdfs:label "regulation of localization" ; rdfs:comment "Any process that modulates the frequency, rate or extent of any process in which a cell, a substance, or a cellular entity is transported to, or maintained in, a specific location." ; rdfs:subClassOf obo:GO_0050789 . obo:CHEBI_34998 a rdfs:Class ; rdfs:label "teicoplanin A2-5" ; rdfs:comment "A teicoplanin A2 that has 9-methyldecanoyl as the variable N-acyl group." ; rdfs:subClassOf obo:CHEBI_34994 . obo:GO_0010518 a rdfs:Class ; rdfs:label "positive regulation of phospholipase activity" ; rdfs:comment "Any process that increases the frequency, rate or extent of phospholipase activity, the hydrolysis of a phospholipid." ; rdfs:subClassOf obo:GO_0010517 , obo:GO_0060193 . obo:GO_0016032 a rdfs:Class ; rdfs:label "viral process" ; rdfs:comment "A multi-organism process in which a virus is a participant. The other participant is the host. Includes infection of a host cell, replication of the viral genome, and assembly of progeny virus particles. In some cases the viral genetic material may integrate into the host genome and only subsequently, under particular circumstances, 'complete' its life cycle." ; rdfs:subClassOf obo:GO_0008150 . obo:CHEBI_37175 a rdfs:Class ; rdfs:label "organic hydride" ; rdfs:subClassOf obo:CHEBI_33692 . a rdfs:Class ; rdfs:label "Isoquinolines [Chemical/Ingredient]" ; rdfs:subClassOf . obo:OPMI_0000506 a rdfs:Class ; rdfs:label "procedure occurrence identifier"@en ; rdfs:comment "A centrally registered identifier that refers to a procedure occurrence, which is an activity or process that is ordered by, or carried out by, a healthcare provider on a patient with a diagnostic or therapeutic purpose." ; rdfs:subClassOf obo:IAO_0000578 . obo:CIDO_0000074 a rdfs:Class ; rdfs:label "chemical role against MERS-CoV replication"@en ; rdfs:subClassOf obo:CIDO_0000072 . obo:CIDO_0001154 a rdfs:Class ; rdfs:label "SARS-CoV-2 S1 NTD protein amino acid deletion"@en ; rdfs:comment "A SARS-CoV-2 protein AA deletion that affected a SARS-CoV-2 S protein in the RBD domain." ; rdfs:subClassOf obo:CIDO_0001145 . a rdfs:Class ; rdfs:label "gemcitabine [Chemical/Ingredient]" ; rdfs:subClassOf . obo:PR_P41145 a rdfs:Class ; rdfs:label "kappa-type opioid receptor (human)" ; rdfs:comment "A kappa-type opioid receptor that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000001590 , obo:PR_000029067 . obo:CHEBI_60334 a rdfs:Class ; rdfs:label "peptide anion" ; rdfs:comment "An anion formed by deprotonation of at least one peptide carboxy group." ; rdfs:subClassOf obo:CHEBI_25696 . obo:PR_Q9ULX6 a rdfs:Class ; rdfs:label "A-kinase anchor protein 8-like (human)" ; rdfs:comment "An A-kinase anchor protein 8-like that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000003895 , obo:PR_000029067 . obo:PR_P34998 a rdfs:Class ; rdfs:label "corticotropin-releasing factor receptor 1 (human)" ; rdfs:comment "A corticotropin-releasing factor receptor 1 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000005869 , obo:PR_000029067 . obo:NCBITaxon_454951 a rdfs:Class ; rdfs:label "Feline coronavirus UU3" ; rdfs:subClassOf obo:NCBITaxon_12663 . obo:GO_0035814 a rdfs:Class ; rdfs:label "negative regulation of renal sodium excretion" ; rdfs:comment "Any process that decreases the amount of sodium excreted in urine over a unit of time." ; rdfs:subClassOf obo:GO_0035813 , obo:GO_0051048 , obo:GO_0051241 . obo:CHEBI_38672 a rdfs:Class ; rdfs:label "flavans" ; rdfs:comment "Any flavonoid with a 3,4-dihydro-2-aryl-2H-1-benzopyran skeleton and its substituted derivatives." ; rdfs:subClassOf obo:CHEBI_26004 , obo:CHEBI_38443 , obo:CHEBI_47916 . obo:OPMI_0000578 a rdfs:Class ; rdfs:label "observation period end date"@en ; rdfs:comment "A date when an observation ends." ; rdfs:subClassOf obo:BFO_0000148 , obo:OPMI_0000576 . obo:CHEBI_76807 a rdfs:Class ; rdfs:label "EC 3.5.1.* (non-peptide linear amide C-N hydrolase) inhibitor" ; rdfs:comment "An EC 3.5.* (hydrolases acting on non-peptide C-N bonds) inhibitor that interferes with the action of any non-peptide linear amide C-N hydrolase (EC 3.5.1.*)." ; rdfs:subClassOf obo:CHEBI_76764 . obo:PR_Q9NNX6 a rdfs:Class ; rdfs:label "CD209 antigen (human)" ; rdfs:comment "A CD209 molecule that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000001300 , obo:PR_000029067 . obo:PR_000004989 a rdfs:Class ; rdfs:label "calcium/calmodulin-dependent protein kinase type 1D" ; rdfs:comment "A protein that is a translation product of the human CAMK1D gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:NCBITaxon_1289551 a rdfs:Class ; rdfs:label "Coronavirus Mex_CoV-5b" ; rdfs:subClassOf obo:NCBITaxon_366617 . obo:GO_0051249 a rdfs:Class ; rdfs:label "regulation of lymphocyte activation" ; rdfs:comment "Any process that modulates the frequency, rate or extent of lymphocyte activation." ; rdfs:subClassOf obo:GO_0002694 . obo:CHEBI_32846 a rdfs:Class ; rdfs:label "serinium" ; rdfs:comment "An alpha-amino-acid cation that is the conjugate acid of serine." ; rdfs:subClassOf obo:CHEBI_33719 . obo:GO_0050982 a rdfs:Class ; rdfs:label "detection of mechanical stimulus" ; rdfs:comment "The series of events by which a mechanical stimulus is received and converted into a molecular signal." ; rdfs:subClassOf obo:GO_0009581 , obo:GO_0009582 , obo:GO_0009612 . obo:HP_0002149 a rdfs:Class ; rdfs:label "Hyperuricemia" ; rdfs:comment "An abnormally high level of uric acid in the blood." ; rdfs:subClassOf obo:HP_0004364 , obo:HP_0010932 . obo:GO_1901362 a rdfs:Class ; rdfs:label "organic cyclic compound biosynthetic process" ; rdfs:comment "The chemical reactions and pathways resulting in the formation of organic cyclic compound." ; rdfs:subClassOf obo:GO_1901360 , obo:GO_1901576 . obo:UBERON_0004119 a rdfs:Class ; rdfs:label "endoderm-derived structure" ; rdfs:comment "An anatomical structure that develops (entirely or partially) from the endoderm." ; rdfs:subClassOf obo:UBERON_0000061 . obo:CHEBI_85094 a rdfs:Class ; rdfs:label "EC 2.7.11.11 (cAMP-dependent protein kinase) inhibitor" ; rdfs:comment "An EC 2.7.11.* (protein-serine/threonine kinase) inhibitor that interferes with the action of cAMP-dependent protein kinase (EC 2.7.11.11)." ; rdfs:subClassOf obo:CHEBI_76812 . a rdfs:Class ; rdfs:label "Emetine [Chemical/Ingredient]" ; rdfs:subClassOf , . obo:CHEBI_35350 a rdfs:Class ; rdfs:label "hydroxy steroid" ; rdfs:subClassOf obo:CHEBI_33822 , obo:CHEBI_35341 . obo:PR_000003244 a rdfs:Class ; rdfs:label "RAF proto-oncogene serine/threonine-protein kinase" ; rdfs:comment "A protein that is a translation product of the human RAF1 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:VO_0005152 a rdfs:Class ; rdfs:label "MVA-MERS-S vaccine" ; rdfs:comment "A MERS recombinant vector made of recombinant modified vaccinia virus Ankara (rMVA) vaccine vector carrying full MERS-CoV spike glycoprotein." ; rdfs:subClassOf obo:VO_0004900 . obo:PR_000002342 a rdfs:Class ; rdfs:label "protein kinase C epsilon" ; rdfs:comment "A protein kinase C, delta-like that is a translation product of the human PRKCE gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000002210 . obo:PR_000013867 a rdfs:Class ; rdfs:label "receptor expression-enhancing protein 5" ; rdfs:comment "A protein that is a translation product of the human REEP5 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:CHEBI_78049 a rdfs:Class ; rdfs:label "octadecenoate" ; rdfs:comment "A fatty acid anion containing 18 carbons and one double bond. Formed by deprotonation of the carboxylic acid group. Major species at pH 7.3." ; rdfs:subClassOf obo:CHEBI_2580 , obo:CHEBI_82680 . obo:PR_P38606 a rdfs:Class ; rdfs:label "V-type proton ATPase catalytic subunit A (human)" ; rdfs:comment "A V-type proton ATPase catalytic subunit A that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000004480 , obo:PR_000029067 . obo:NCBITaxon_1897069 a rdfs:Class ; rdfs:label "Bat coronavirus Art.lit/2294/BRA/2012" ; rdfs:subClassOf obo:NCBITaxon_366617 . a rdfs:Class ; rdfs:label "Pericarditis, Constrictive [Disease/Finding]" ; rdfs:subClassOf . obo:UBERON_0006911 a rdfs:Class ; rdfs:label "digestive system secreted substance" ; rdfs:subClassOf obo:UBERON_0000463 . obo:CHEBI_168397 a rdfs:Class ; rdfs:label "Ganolucidic acid A" ; rdfs:subClassOf obo:CHEBI_36615 . obo:CIDO_0000439 a rdfs:Class ; rdfs:label "COVID-19 diagnostic process using RT-PCR"@en ; rdfs:comment "A COVID-19 diagnostic process that uses a reverse transcription polymerase chain reaction (rRT -PCR) test" ; rdfs:subClassOf obo:CIDO_0000038 . obo:CIDO_0020342 a rdfs:Class ; rdfs:label "Solaris Multiplex SARS-CoV-2 Assay" ; rdfs:seeAlso ; rdfs:subClassOf obo:CIDO_0000454 . obo:NCBITaxon_314293 a rdfs:Class ; rdfs:label "Simiiformes" ; rdfs:subClassOf obo:NCBITaxon_314146 , obo:NCBITaxon_376913 . obo:PR_P11802 a rdfs:Class ; rdfs:label "cyclin-dependent kinase 4 (human)" ; rdfs:comment "A cell division protein kinase 4 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000005257 , obo:PR_000029067 . obo:CHEBI_38093 a rdfs:Class ; rdfs:label "phenothiazines" ; rdfs:subClassOf obo:CHEBI_26979 . obo:CIDO_0000082 a rdfs:Class ; rdfs:label "chemical role modulating host immune response to SARS-CoV infection"@en ; rdfs:comment "A role of a chemical effective in modulating host response to SARS-CoV infection" ; rdfs:subClassOf obo:CIDO_0000080 . obo:HP_0002205 a rdfs:Class ; rdfs:label "Recurrent respiratory infections" ; rdfs:comment "An increased susceptibility to respiratory infections as manifested by a history of recurrent respiratory infections." ; rdfs:subClassOf obo:HP_0011947 , obo:HP_0032101 . obo:PR_000031125 a rdfs:Class ; rdfs:label "MAP7 domain-containing protein 1" ; rdfs:comment "A protein that is a translation product of the human MAP7D1 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:PR_O00566 a rdfs:Class ; rdfs:label "U3 small nucleolar ribonucleoprotein protein MPP10 (human)" ; rdfs:comment "A U3 small nucleolar ribonucleoprotein protein MPP10 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000010536 , obo:PR_000029067 . obo:OBI_0002124 a rdfs:Class ; rdfs:label "H&E slide staining"@en ; rdfs:comment "A staining using hematoxylin and eosin. The staining is applied to fixed specimens on slides to observe the whole structure and morphology of cells in a tissue; nuclei are stained dark blue/purple while cytoplasm is stained pink."@en ; rdfs:subClassOf obo:OBI_0302887 . obo:DRON_00837869 a rdfs:Class ; rdfs:label "gilteritinib" ; rdfs:subClassOf obo:OBI_0000047 . obo:CIDO_0020327 a rdfs:Class ; rdfs:label "Visby Medical COVID-19 Point of Care Test" ; rdfs:seeAlso ; rdfs:subClassOf obo:CIDO_0000454 . obo:NCBITaxon_9625 a rdfs:Class ; rdfs:label "Vulpes" ; rdfs:subClassOf obo:NCBITaxon_9608 . obo:NCBITaxon_756646 a rdfs:Class ; rdfs:label "Bovine coronavirus cow/WDBR-1005/BRA/2003" ; rdfs:subClassOf obo:NCBITaxon_11128 . obo:CHEBI_60242 a rdfs:Class ; rdfs:label "monovalent inorganic cation" ; rdfs:comment "An atom or small molecule with a positive charge that does not contain carbon in covalent linkage, with a valency of one." ; rdfs:subClassOf obo:CHEBI_36915 . obo:PR_000044628 a rdfs:Class ; rdfs:label "voltage-gated ion channel protein" ; rdfs:comment "An ion channel protein that has voltage-gated ion channel activity. A voltage-gated ion channel enables the transmembrane transfer of a solute by a channel whose open state is dependent on the voltage across the membrane in which it is embedded." ; rdfs:subClassOf obo:PR_000049983 . obo:CHEBI_25442 a rdfs:Class ; rdfs:label "mycotoxin" ; rdfs:comment "Poisonous substance produced by fungi." ; rdfs:subClassOf obo:CHEBI_27026 , obo:CHEBI_76946 . obo:CHEBI_36343 a rdfs:Class ; rdfs:label "composite particle" ; rdfs:comment "A subatomic particle known to have substructure (i.e. consisting of smaller particles)." ; rdfs:subClassOf obo:CHEBI_36342 . obo:PR_P09038 a rdfs:Class ; rdfs:label "fibroblast growth factor 2 (human)" ; rdfs:comment "A fibroblast growth factor 2 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000007489 , obo:PR_000029067 . obo:PR_P0DTG0 a rdfs:Class ; rdfs:label "putative ORF3d protein (SARS-CoV-2)" ; rdfs:comment "A protein that is a translation product of the ORF3d gene in SARS-CoV-2." ; rdfs:subClassOf obo:PR_000050262 . obo:NCBITaxon_749430 a rdfs:Class ; rdfs:label "Pintail coronavirus PBA-15" ; rdfs:subClassOf obo:NCBITaxon_749416 . obo:CIDO_0000458 a rdfs:Class ; rdfs:label "CLIA certified High complexity laboratory"@en ; rdfs:comment "A CLIA certified laboratory that is categorized as a high complexity defined by the criteria listed in 42CFR 493.17 based on the Clinical Laboratory Improvement Amendments (CLIA) regulattion." ; rdfs:subClassOf obo:CIDO_0000457 . obo:CIDO_0001051 a rdfs:Class ; rdfs:label "SARS-CoV2 orf9c protein binding to human F2RL1" ; rdfs:comment "SARS-CoV2 orf9c protein binding to human F2RL1, as evidented by an affinity-purification mass spectrometry experiment" ; rdfs:subClassOf obo:CIDO_0000054 . obo:OAE_0000580 a rdfs:Class ; rdfs:label "behavioral and neurological AE" ; rdfs:comment "an adverse event that has an outcome of an abnormal behavior and neurological phenotype." ; rdfs:subClassOf obo:OAE_0000001 . obo:PR_000018264 a rdfs:Class ; rdfs:label "proteolytic cleavage product" ; rdfs:comment "A protein that is produced as the result of proteolytic processing of a longer protein." ; rdfs:subClassOf obo:PR_000000001 . obo:CHEBI_59871 a rdfs:Class ; rdfs:label "D-alpha-amino acid zwitterion" ; rdfs:comment "Zwitterionic form of a D-alpha-amino acid having an anionic carboxy group and a protonated amino group." ; rdfs:subClassOf obo:CHEBI_35238 . obo:GO_0007632 a rdfs:Class ; rdfs:label "visual behavior" ; rdfs:comment "The behavior of an organism in response to a visual stimulus." ; rdfs:subClassOf obo:GO_0007610 , obo:GO_0009314 . a rdfs:Class ; rdfs:label "Organized Electrical Activity Alteration [PE]" ; rdfs:subClassOf . obo:NCBITaxon_422215 a rdfs:Class ; rdfs:label "Bovine coronavirus R-AH65-TC" ; rdfs:subClassOf obo:NCBITaxon_422214 . obo:CIDO_0020200 a rdfs:Class ; rdfs:label "Maverick SARS-CoV-2 Multi-Antigen Serology Panel v2" ; rdfs:seeAlso ; rdfs:subClassOf obo:CIDO_0000454 . obo:PR_000036816 a rdfs:Class ; rdfs:label "dengue virus genome polyprotein" ; rdfs:comment "A protein that is a translation product of the dengue virus serotype 2 genomic RNA or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:PR_000003262 a rdfs:Class ; rdfs:label "collagen alpha chain" ; rdfs:comment "A protein that is a component of collagen. Collagens are trimeric molecules in which each chain comprises a repeating Gly-X-Y triplet, in which X and Y can be any residue but are usually proline and hydroxyproline, respectively. This results in a left-handed helix that combines with other two to form a triple-helical structure." ; rdfs:subClassOf obo:PR_000000001 . obo:GO_0045907 a rdfs:Class ; rdfs:label "positive regulation of vasoconstriction" ; rdfs:comment "Any process that activates or increases the frequency, rate or extent of vasoconstriction." ; rdfs:subClassOf obo:GO_0019229 , obo:GO_0051240 . obo:CHEBI_84186 a rdfs:Class ; rdfs:label "L-proline derivative" ; rdfs:comment "A proteinogenic amino acid derivative resulting from reaction of L-proline at the amino group or the carboxy group, or from the replacement of any hydrogen of L-proline by a heteroatom." ; rdfs:subClassOf obo:CHEBI_26273 , obo:CHEBI_83811 . obo:PR_000001662 a rdfs:Class ; rdfs:label "proteinase-activated receptor 2" ; rdfs:comment "A proteinase-activated receptor that is a translation product of the human F2RL1 gene or a 1:1 ortholog thereof. It is activated by trypsin and trypsin-like proteinases, which cleave the mature peptide, exposing a new amino end. The six new N-terminal residues act as a tethered ligand that induces activity." ; rdfs:subClassOf obo:PR_000001550 . obo:PR_000002186 a rdfs:Class ; rdfs:label "Bcl-2-like apoptosis inhibitor" ; rdfs:comment "A protein that is a translation product of the human BCL2, BCL2L1, or BCL2L2 genes, 1:1 orthologs thereof, or a semi-ortholog thereof. The core domain architecture consists of an amino-terminal BH4 domain (Pfam:PF02180), which confers apoptosis inhibitory activity, and a Bcl-2 domain (Pfam:PF02180) common to many apoptosis regulator proteins." ; rdfs:subClassOf obo:PR_000000001 . obo:CIDO_0001022 a rdfs:Class ; rdfs:label "Zansecimab" ; rdfs:subClassOf obo:CHEBI_23367 . obo:CHEBI_61283 a rdfs:Class ; rdfs:label "baicalin(1-)" ; rdfs:comment "The carbohydrate acid derivative anion that is the conjugate base of baicalin." ; rdfs:subClassOf obo:CHEBI_35757 , obo:CHEBI_63551 . obo:APOLLO_SV_00000486 a rdfs:Class ; rdfs:label "travel-related infectious disease control strategy"@en ; rdfs:comment "An infectious disease control strategy that has an objective specification of preventing infection acquisition by organisms traveling from one ecosystem to another ecosystem."@en ; rdfs:subClassOf obo:APOLLO_SV_00000086 . obo:CIDO_0020214 a rdfs:Class ; rdfs:label "Nirmidas COVID-19 (SARS-CoV-2) IgM/IgG Antibody Detection Kit" ; rdfs:seeAlso ; rdfs:subClassOf obo:CIDO_0000454 . obo:CIDO_0020107 a rdfs:Class ; rdfs:label "Cue COVID-19 Test" ; rdfs:seeAlso ; rdfs:subClassOf obo:CIDO_0000454 . obo:PR_Q08881 a rdfs:Class ; rdfs:label "tyrosine-protein kinase ITK/TSK (human)" ; rdfs:comment "A tyrosine-protein kinase ITK/TSK that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000002111 , obo:PR_000029067 . obo:CIDO_0000835 a rdfs:Class ; rdfs:label "SARS-CoV2 nsp13 protein binding to human CNTRL" ; rdfs:comment "SARS-CoV2 nsp13 protein binding to human CNTRL, as evidented by an affinity-purification mass spectrometry experiment" ; rdfs:subClassOf obo:CIDO_0000058 . obo:PR_P09884 a rdfs:Class ; rdfs:label "DNA polymerase alpha catalytic subunit (human)" ; rdfs:comment "A DNA polymerase alpha catalytic subunit that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000012960 , obo:PR_000029067 . obo:IDO_0000500 a rdfs:Class ; rdfs:label "variolation"@en ; rdfs:comment "An active immunization that begins with exposure to smallpox in the form of a scab from a pustule and results in immunity against smallpox."@en ; rdfs:subClassOf obo:IDO_0000498 . obo:GO_0051051 a rdfs:Class ; rdfs:label "negative regulation of transport" ; rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of substances (such as macromolecules, small molecules, ions) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." ; rdfs:subClassOf obo:GO_0048519 , obo:GO_0051049 . obo:OGG_3000006352 a rdfs:Class ; rdfs:label "CCL5" ; rdfs:comment "Other designations: C-C motif chemokine 5|T-cell specific protein p288|beta-chemokine RANTES|eosinophil chemotactic cytokine|regulated upon activation, normally T-expressed, and presumably secreted|small inducible cytokine subfamily A (Cys-Cys), member 5" ; rdfs:subClassOf obo:OGG_2060009606 . obo:CHEBI_132967 a rdfs:Class ; rdfs:label "elbasvir" ; rdfs:comment "A complex organic heterotetracyclic compound that is a hepatitis C virus nonstructural protein 5A inhibitor used in combination with grazoprevir (under the brand name Zepatier) for treatment of chronic HCV genotypes 1 or 4 infection in adults." ; rdfs:subClassOf obo:CHEBI_23003 , obo:CHEBI_24780 , obo:CHEBI_36820 , obo:CHEBI_38163 , obo:CHEBI_46766 , obo:CHEBI_84129 . obo:PR_P48736 a rdfs:Class ; rdfs:label "phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (human)" ; rdfs:comment "A phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000012722 , obo:PR_000029067 . a rdfs:Class ; rdfs:label "Bacterial Infections [Disease/Finding]" ; rdfs:subClassOf . obo:NCBITaxon_1788482 a rdfs:Class ; rdfs:label "Miniopterus bat coronavirus BtCoV/4068-2" ; rdfs:subClassOf obo:NCBITaxon_2664420 . a rdfs:Class ; rdfs:label "penciclovir [Chemical/Ingredient]" ; rdfs:subClassOf . a rdfs:Class ; rdfs:label "Signs and Symptoms [Disease/Finding]" ; rdfs:subClassOf . obo:NCBITaxon_264387 a rdfs:Class ; rdfs:label "SARS coronavirus TW-PH1" ; rdfs:subClassOf obo:NCBITaxon_264370 . obo:NCBITaxon_1881089 a rdfs:Class ; rdfs:label "Myotis latirostis coronavirus" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:NCBITaxon_1146856 a rdfs:Class ; rdfs:label "Bat coronavirus M.nattereri/UK/Sav/1095A" ; rdfs:subClassOf obo:NCBITaxon_366617 . obo:OGG_3043740574 a rdfs:Class ; rdfs:label "ORF7b of severe acute respiratory syndrome coronavirus 2" ; rdfs:subClassOf obo:OGG_2002697049 . obo:CIDO_0020065 a rdfs:Class ; rdfs:label "BMC-CReM COVID-19 Test" ; rdfs:seeAlso ; rdfs:subClassOf obo:CIDO_0000454 . obo:GO_0044238 a rdfs:Class ; rdfs:label "primary metabolic process" ; rdfs:comment "The chemical reactions and pathways involving those compounds which are formed as a part of the normal anabolic and catabolic processes. These processes take place in most, if not all, cells of the organism." ; rdfs:subClassOf obo:GO_0008152 . obo:CHEBI_33300 a rdfs:Class ; rdfs:label "pnictogen" ; rdfs:comment "Any p-block element atom that is in group 15 of the periodic table: nitrogen, phosphorus, arsenic, antimony and bismuth." ; rdfs:subClassOf obo:CHEBI_33560 . obo:CIDO_0020010 a rdfs:Class ; rdfs:label "ADVIA Centaur SARS-CoV-2 IgG (COV2G)" ; rdfs:seeAlso ; rdfs:subClassOf obo:CIDO_0000454 . obo:CIDO_0000169 a rdfs:Class ; rdfs:label "COVID-19 drug substance"@en ; rdfs:comment "A drug substance that is experinentallly proven to be effective against SARS-CoV-2 infection, where the experiment can be done either in vivo or in vitro. The in vitro study is typically conducted using cell line cells." ; rdfs:subClassOf obo:CIDO_0000167 . obo:CHEBI_47916 a rdfs:Class ; rdfs:label "flavonoid" ; rdfs:comment "Any member of the 'superclass' flavonoids whose skeleton is based on 1-benzopyran with an aryl substituent at position 2. The term was originally restricted to natural products, but is now also used to describe semi-synthetic and fully synthetic compounds." ; rdfs:subClassOf obo:CHEBI_72544 . obo:OAE_0001926 a rdfs:Class ; rdfs:label "throat irritation AE" ; rdfs:comment "Throat irritation AE is a discomfort AE that refers to a dry cough, a scratchy feeling at the back of the throat, or a sensation of a lumpy feeling or something stuck at the back of the throat." ; rdfs:subClassOf obo:OAE_0000081 . obo:CHEBI_39547 a rdfs:Class ; rdfs:label "(R)-carnitinium" ; rdfs:comment "A carnitinium that is the conjugate acid of (R)-carnitine." ; rdfs:subClassOf obo:CHEBI_3424 . obo:PR_000000176 a rdfs:Class ; rdfs:label "GTP-binding protein RhoA" ; rdfs:comment "A Rho-related small GTPase that is a translation product of the human RHOA gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000122 . obo:NCBITaxon_2042559 a rdfs:Class ; rdfs:label "Coronavirus PREDICT CoV-34" ; rdfs:subClassOf obo:NCBITaxon_696098 . obo:NCBITaxon_241183 a rdfs:Class ; rdfs:label "SARS coronavirus BJ2232" ; rdfs:subClassOf obo:NCBITaxon_694009 . obo:PR_Q9UK32 a rdfs:Class ; rdfs:label "ribosomal protein S6 kinase alpha-6 (human)" ; rdfs:comment "A ribosomal protein S6 kinase alpha-6 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000014287 , obo:PR_000029067 . obo:NCBITaxon_9604 a rdfs:Class ; rdfs:label "Hominidae" ; rdfs:subClassOf obo:NCBITaxon_314295 . obo:OPMI_0000550 a rdfs:Class ; rdfs:label "preliminary discharge diagnosis status"@en ; rdfs:comment "The status of have the primary admission diagnosis" ; rdfs:subClassOf obo:OPMI_0000540 . obo:OBI_0000319 a rdfs:Class ; rdfs:label "material to be added role"@en ; rdfs:comment "material to be added role is a protocol participant role realized by a material which is added into a material bearing the target of material addition role in a material addition process"@en ; rdfs:subClassOf obo:BFO_0000023 . obo:CIDO_0000536 a rdfs:Class ; rdfs:label "QPVEGVSSFMNVTLD" ; rdfs:comment "A coronavirus epitope that is part of some S protein from HCoV 229E composed of the following amino acids QPVEGVSSFMNVTLD" ; rdfs:subClassOf obo:CIDO_0000451 . obo:CIDO_0000002 a rdfs:Class ; rdfs:label "SARS-CoV disease process"@en ; rdfs:comment """SARS was a relatively rare disease; at the end of the epidemic in June 2003, the incidence was 8422 cases with a case-fatality rate of 11%. The case-fatality ratio ranges from 0% to 50% depending on the age group of the patient. Patients under 24 were least likely to die; those 65 and older were most likely to die. Reference: https://en.wikipedia.org/wiki/Severe_acute_respiratory_syndrome""" ; rdfs:subClassOf obo:CIDO_0000001 . obo:OBI_0000888 a rdfs:Class ; rdfs:label "nuclear RNA extraction" ; rdfs:comment "A RNA extraction process in which the desired output material is RNA in the nucleus." ; rdfs:subClassOf obo:OBI_0666666 . obo:PR_000001708 a rdfs:Class ; rdfs:label "sphingosine 1-phosphate receptor 3" ; rdfs:comment "A lysophospholipid (S1P) receptor that is a translation product of the human S1PR3 gene or a 1:1 ortholog thereof. It is expressed in all tissues, but most abundantly in heart, placenta, kidney, and liver." ; rdfs:subClassOf obo:PR_000001673 . obo:NCBITaxon_1403203 a rdfs:Class ; rdfs:label "Coronavirus PgCoV-1" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:GO_0051224 a rdfs:Class ; rdfs:label "negative regulation of protein transport" ; rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of a protein into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." ; rdfs:subClassOf obo:GO_0051051 , obo:GO_0051223 , obo:GO_1904950 . obo:UBERON_0001836 a rdfs:Class ; rdfs:label "saliva" ; rdfs:comment "A fluid produced in the oral cavity by salivary glands, typically used in predigestion, but also in other functions." ; rdfs:subClassOf obo:UBERON_0000463 . obo:CHEBI_36380 a rdfs:Class ; rdfs:label "emetan" ; rdfs:subClassOf obo:CHEBI_24921 , obo:CHEBI_24922 , obo:CHEBI_38515 . obo:VO_0001267 a rdfs:Class ; rdfs:label "saponin vaccine adjuvant" ; rdfs:comment "a tensoactive compound vaccine adjuvant that is derived from saponin, a compound that is an immunostimulator found in the plant P. senega." ; rdfs:subClassOf obo:VO_0001358 . obo:NCBITaxon_1962851 a rdfs:Class ; rdfs:label "Dromedary camel coronavirus" ; rdfs:subClassOf obo:NCBITaxon_696098 . obo:NCBITaxon_398808 a rdfs:Class ; rdfs:label "Bovine coronavirus DB2" ; rdfs:subClassOf obo:NCBITaxon_11128 . obo:PR_000031063 a rdfs:Class ; rdfs:label "CAP-Gly domain-containing linker protein 4" ; rdfs:comment "A protein that is a translation product of the human CLIP4 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:PR_000007122 a rdfs:Class ; rdfs:label "ephrin type-A receptor 2" ; rdfs:comment "An ephrin receptor that is a translation product of the human EPHA2 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000025845 . obo:CHEBI_65321 a rdfs:Class ; rdfs:label "terpenoid indole alkaloid" ; rdfs:comment "An indole alkaloid which is biosynthesised from L-tryptophan and isoprenoid building blocks." ; rdfs:subClassOf obo:CHEBI_38958 . obo:OAE_0000435 a rdfs:Class ; rdfs:label "muscle AE" ; rdfs:comment "a musculoskeletal system AE that occurs in muscle." ; rdfs:subClassOf obo:OAE_0000027 . obo:OPMI_0000455 a rdfs:Class ; rdfs:label "predictive biomarker"@en ; rdfs:comment "A biomarker that can predict clincal outcome." ; rdfs:subClassOf obo:OPMI_0000445 . obo:GO_0022409 a rdfs:Class ; rdfs:label "positive regulation of cell-cell adhesion" ; rdfs:comment "Any process that activates or increases the rate or extent of cell adhesion to another cell." ; rdfs:subClassOf obo:GO_0022407 , obo:GO_0045785 . obo:NCBITaxon_996630 a rdfs:Class ; rdfs:label "Bat coronavirus M.ful/Japan/03/2010" ; rdfs:subClassOf obo:NCBITaxon_366617 . obo:PR_P45983 a rdfs:Class ; rdfs:label "mitogen-activated protein kinase 8 (human)" ; rdfs:comment "A mitogen-activated protein kinase 8 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000002206 , obo:PR_000029067 . obo:PR_Q16512 a rdfs:Class ; rdfs:label "serine/threonine-protein kinase N1 (human)" ; rdfs:comment "A serine/threonine-protein kinase N1 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000012785 , obo:PR_000029067 . obo:PR_000011196 a rdfs:Class ; rdfs:label "peptide-N(4)-(N-acetyl-beta-glucosaminyl)asparagine amidase" ; rdfs:comment "A protein that is a translation product of the human NGLY1 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . a rdfs:Class ; rdfs:label "Mouth Diseases [Disease/Finding]" ; rdfs:subClassOf . obo:PR_Q8N8E3 a rdfs:Class ; rdfs:label "centrosomal protein of 112 kDa (human)" ; rdfs:comment "A centrosomal protein of 112 kDa that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000029067 , obo:PR_000031145 . obo:CHEBI_38264 a rdfs:Class ; rdfs:label "2-amino-3-methylpentanoic acid" ; rdfs:comment "A branched chain amino acid that consists of 3-methylpentanoic acid bearing an amino substituent at position 2." ; rdfs:subClassOf obo:CHEBI_22918 , obo:CHEBI_33704 . obo:CHEBI_16134 a rdfs:Class ; rdfs:label "ammonia" ; rdfs:comment "An azane that consists of a single nitrogen atom covelently bonded to three hydrogen atoms." ; rdfs:subClassOf obo:CHEBI_138675 , obo:CHEBI_35107 , obo:CHEBI_37176 . obo:OBI_0200078 a rdfs:Class ; rdfs:label "descriptive statistical calculation objective"@en ; rdfs:comment "A descriptive statistical calculation objective is a data transformation objective which concerns any calculation intended to describe a feature of a data set, for example, its center or its variability."@en ; rdfs:subClassOf obo:OBI_0200166 . obo:PR_Q06203 a rdfs:Class ; rdfs:label "amidophosphoribosyltransferase (human)" ; rdfs:comment "An amidophosphoribosyltransferase that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000013061 , obo:PR_000029067 . obo:PR_000016324 a rdfs:Class ; rdfs:label "thiamine-triphosphatase" ; rdfs:comment "A protein that is a translation product of the human THTPA gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:DRON_00021685 a rdfs:Class ; rdfs:label "Chlorpromazine / Dipyrone Oral Solution" ; rdfs:subClassOf obo:DRON_00000020 . obo:PR_000008656 a rdfs:Class ; rdfs:label "histamine N-methyltransferase" ; rdfs:comment "A protein that is a translation product of the human HNMT gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:CHEBI_27965 a rdfs:Class ; rdfs:label "conessine" ; rdfs:comment "A steroid alkaloid that is con-5-enine substituted by a N,N-dimethylamino group at position 3. It has been isolated from the plant species of the family Apocynaceae." ; rdfs:subClassOf obo:CHEBI_26767 , obo:CHEBI_50996 . obo:PR_000003800 a rdfs:Class ; rdfs:label "TLE family member 5" ; rdfs:comment "A protein that is a translation product of the human TLE5 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:GO_0072594 a rdfs:Class ; rdfs:label "establishment of protein localization to organelle" ; rdfs:comment "The directed movement of a protein to a specific location on or in an organelle. Encompasses establishment of localization in the membrane or lumen of a membrane-bounded organelle." ; rdfs:subClassOf obo:GO_0033365 , obo:GO_0045184 . obo:OBI_0002778 a rdfs:Class ; rdfs:label "tracheal aspirate specimen" ; rdfs:comment "A specimen that is collected with a suctioning tube from the trachea." ; rdfs:subClassOf obo:OBI_0002599 . obo:CIDO_0000396 a rdfs:Class ; rdfs:label "SARS-CoV-2 B.1.135 virus"@en ; rdfs:comment "A SARS-CoV-2 Beta variant virus that has a majority of the following mutations: E:P71L, N:T205I, orf1a:K1655N, S:D80A, S:D215G, S:K417N, S:A701V, S:N501Y, S:E484K" ; rdfs:subClassOf obo:CIDO_0000375 , obo:CIDO_0000406 . obo:NCBITaxon_1699339 a rdfs:Class ; rdfs:label "Myotis Bat Alphacoronavirus strain YNXY_44C" ; rdfs:subClassOf obo:NCBITaxon_366617 . a rdfs:Class ; rdfs:label "Special Sensory Systems Activity Alteration [PE]" ; rdfs:subClassOf . a rdfs:Class ; rdfs:label "Large Intestine Fluid/Electrolyte Alteration [PE]" ; rdfs:subClassOf . obo:GO_0009893 a rdfs:Class ; rdfs:label "positive regulation of metabolic process" ; rdfs:comment "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways within a cell or an organism." ; rdfs:subClassOf obo:GO_0019222 , obo:GO_0048518 . obo:CHEBI_4705 a rdfs:Class ; rdfs:label "double-stranded DNA" ; rdfs:subClassOf obo:CHEBI_16991 . obo:UBERON_0002037 a rdfs:Class ; rdfs:label "cerebellum" ; rdfs:comment "Part of the metencephalon that lies in the posterior cranial fossa behind the brain stem. It is concerned with the coordination of movement[MESH]. A large dorsally projecting part of the brain concerned especially with the coordination of muscles and the maintenance of bodily equilibrium, situated between the brain stem and the back of the cerebrum , and formed in humans of two lateral lobes and a median lobe[BTO]. Brain structure derived from the anterior hindbrain, and perhaps including posterior midbrain. The cerebellum plays a role in somatic motor function, the control of muscle tone, and balance[ZFA]." ; rdfs:subClassOf obo:UBERON_0000481 . obo:PR_Q9H488 a rdfs:Class ; rdfs:label "GDP-fucose protein O-fucosyltransferase 1 (human)" ; rdfs:comment "A GDP-fucose protein O-fucosyltransferase 1 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000012958 , obo:PR_000029067 . a rdfs:Class ; rdfs:label "Adenophorea Infections [Disease/Finding]" ; rdfs:subClassOf . obo:DRON_00019459 a rdfs:Class ; rdfs:label "telavancin" ; rdfs:subClassOf obo:OBI_0000047 . obo:PR_000016350 a rdfs:Class ; rdfs:label "mitochondrial import inner membrane translocase subunit Tim8 B" ; rdfs:comment "A protein that is a translation product of the human TIMM8B gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . a rdfs:Class ; rdfs:label "Ovarian Endocrine Activity Alteration [PE]" ; rdfs:subClassOf . obo:PR_Q9Y4K4 a rdfs:Class ; rdfs:label "mitogen-activated protein kinase kinase kinase kinase 5 (human)" ; rdfs:comment "A mitogen-activated protein kinase kinase kinase kinase 5 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000010146 , obo:PR_000029067 . a rdfs:Class ; rdfs:label "Thioxanthenes [Chemical/Ingredient]" ; rdfs:subClassOf , . obo:NCBITaxon_693998 a rdfs:Class ; rdfs:label "Rhinolophus bat coronavirus HKU2" ; rdfs:subClassOf obo:NCBITaxon_2509509 . obo:HP_0031417 a rdfs:Class ; rdfs:label "Rhinorrhea" ; rdfs:comment "Increased discharge of mucus from the nose." ; rdfs:subClassOf obo:HP_0002795 . obo:GO_1903902 a rdfs:Class ; rdfs:label "positive regulation of viral life cycle" ; rdfs:comment "Any process that activates or increases the frequency, rate or extent of viral life cycle." ; rdfs:subClassOf obo:GO_0048524 , obo:GO_1903900 . obo:CHEBI_3755 a rdfs:Class ; rdfs:label "clomipramine hydrochloride" ; rdfs:comment "A hydrochloride resulting from the reaction of equimolar amounts of clomipramine and hydrogen chloride. One of the more sedating tricyclic antidepressants, it is used for the treatment of depression as well as obsessive-compulsive disorder and phobias." ; rdfs:subClassOf obo:CHEBI_36807 . a rdfs:Class ; rdfs:label "Cycloparaffins [Chemical/Ingredient]" ; rdfs:subClassOf , . obo:GO_0010513 a rdfs:Class ; rdfs:label "positive regulation of phosphatidylinositol biosynthetic process" ; rdfs:comment "Any process that increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of phosphatidylinositol." ; rdfs:subClassOf obo:GO_0071071 , obo:GO_0071073 . a rdfs:Class ; rdfs:label "Pneumonia, Bacterial [Disease/Finding]" ; rdfs:subClassOf , . obo:GO_0034645 a rdfs:Class ; rdfs:label "cellular macromolecule biosynthetic process" ; rdfs:comment "The chemical reactions and pathways resulting in the formation of a macromolecule, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass, carried out by individual cells." ; rdfs:subClassOf obo:GO_0009059 , obo:GO_0044249 , obo:GO_0044260 . obo:NCBITaxon_497941 a rdfs:Class ; rdfs:label "Bat coronavirus M.bec/Germany/D6.6/2007" ; rdfs:subClassOf obo:NCBITaxon_366617 . obo:CHEBI_27208 a rdfs:Class ; rdfs:label "unsaturated fatty acid" ; rdfs:comment "Any fatty acid containing at least one C=C or C#C bond." ; rdfs:subClassOf obo:CHEBI_35366 . obo:PR_000005327 a rdfs:Class ; rdfs:label "centromere protein F" ; rdfs:comment "A protein that is a translation product of the human CENPF gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:NCBITaxon_253435 a rdfs:Class ; rdfs:label "SARS coronavirus PUMC03" ; rdfs:subClassOf obo:NCBITaxon_694009 . obo:NCBITaxon_1788497 a rdfs:Class ; rdfs:label "Rhinolophus bat coronavirus BtCoV/4991" ; rdfs:subClassOf obo:NCBITaxon_2664420 . a rdfs:Class ; rdfs:label "Small Ion Transport Pump Interactions [MoA]" ; rdfs:subClassOf . obo:NCBITaxon_1146862 a rdfs:Class ; rdfs:label "Bat coronavirus M.nattereri/UK/Wyt/1019A" ; rdfs:subClassOf obo:NCBITaxon_366617 . a rdfs:Class ; rdfs:label "Hepatitis, Chronic [Disease/Finding]" ; rdfs:subClassOf . obo:OGG_3000001440 a rdfs:Class ; rdfs:label "CSF3" ; rdfs:comment "Other designations: filgrastim|granulocyte colony-stimulating factor|lenograstim|pluripoietin" ; rdfs:subClassOf obo:OGG_2060009606 . obo:PR_Q9C0B5 a rdfs:Class ; rdfs:label "palmitoyltransferase ZDHHC5 (human)" ; rdfs:comment "A palmitoyltransferase ZDHHC5 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000029067 , obo:PR_000031752 . obo:PR_Q9UIK4 a rdfs:Class ; rdfs:label "death-associated protein kinase 2 (human)" ; rdfs:comment "A death-associated protein kinase 2 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000006277 , obo:PR_000029067 . obo:PR_P28335 a rdfs:Class ; rdfs:label "5-hydroxytryptamine receptor 2C (human)" ; rdfs:comment "A 5-hydroxytryptamine receptor 2C that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000001168 , obo:PR_000029067 . obo:BFO_0000031 a rdfs:Class ; rdfs:label "generically dependent continuant"@en ; rdfs:comment "A continuant that is dependent on one or other independent continuant bearers. For every instance of A requires some instance of (an independent continuant type) B but which instance of B serves can change from time to time."@en ; rdfs:subClassOf obo:BFO_0000002 . obo:CIDO_0001094 a rdfs:Class ; rdfs:label "SARS-CoV2 orf8 protein binding to human MFGE8"@en ; rdfs:comment "SARS-CoV2 orf8 protein binding to human MFGE8, as evidented by an affinity-purification mass spectrometry experiment" ; rdfs:subClassOf obo:CIDO_0000051 . obo:CIDO_0000238 a rdfs:Class ; rdfs:label "D614G in SARS-CoV-2 S protein"@en ; rdfs:comment "The Spike D614G amino acid change is caused by an A-to-G nucleotide mutation at position 23,403 (A23403G) in the Wuhan reference strain; it was the only site identified in our first Spike variation analysis in early March 2020 that met our threshold criterion." ; rdfs:subClassOf obo:CIDO_0001156 . a rdfs:Class ; rdfs:label "Cellular Growth Phase Alteration [PE]" ; rdfs:subClassOf . obo:CHEBI_3647 a rdfs:Class ; rdfs:label "Chlorpromazine" ; rdfs:comment "A substituted phenothiazine in which the ring nitrogen at position 10 is attached to C-3 of an N,N-dimethylpropanamine moiety." ; rdfs:subClassOf obo:CHEBI_32876 , obo:CHEBI_36683 , obo:CHEBI_38093 . obo:PR_000025350 a rdfs:Class ; rdfs:label "HSPC protein" ; rdfs:comment "An Hsp70 family chaperone that contains an ATPase and HSP90 domains." ; rdfs:subClassOf obo:PR_000003425 . obo:OBI_0000067 a rdfs:Class ; rdfs:label "evaluant role"@en ; rdfs:comment "a role that inheres in a material entity that is realized in an assay in which data is generated about the bearer of the evaluant role"@en ; rdfs:subClassOf obo:BFO_0000023 . obo:NCBITaxon_2691584 a rdfs:Class ; rdfs:label "unclassified Duvinacovirus" ; rdfs:subClassOf obo:NCBITaxon_2509480 . obo:PR_000050273 a rdfs:Class ; rdfs:label "non-structural protein 4 (SARS-CoV-2)" ; rdfs:comment "A rep gene proteolytic cleavage product (SARS-CoV-2) that is the central portion produced by the combined actions of PL-PRO proteinase (nsp3) when it cleaves the precursor rep gene translation product (SARS-CoV-2) between residues 2763-2764, and 3CL-PRO (nsp5) when it cleaves the precursor between residues 3263-3264." ; rdfs:subClassOf obo:PR_000050281 . obo:PR_P61006 a rdfs:Class ; rdfs:label "Ras-related protein Rab-8A (human)" ; rdfs:comment "A Ras-related protein Rab-8A that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000013642 , obo:PR_000029067 . a rdfs:Class ; rdfs:label "Puberty, Precocious [Disease/Finding]" ; rdfs:subClassOf . obo:NCBITaxon_424362 a rdfs:Class ; rdfs:label "Bat coronavirus HKU4-4" ; rdfs:subClassOf obo:NCBITaxon_694007 . obo:CIDO_0020328 a rdfs:Class ; rdfs:label "VITROS Immunodiagnostic Products Anti-SARS-CoV-2 IgG Reagent Pack" ; rdfs:seeAlso ; rdfs:subClassOf obo:CIDO_0000454 . obo:PR_P15692 a rdfs:Class ; rdfs:label "vascular endothelial growth factor A (human)" ; rdfs:comment "A vascular endothelial growth factor A that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000017284 , obo:PR_000029067 . obo:CHEBI_50733 a rdfs:Class ; rdfs:label "nutraceutical" ; rdfs:comment "A product in capsule, tablet or liquid form that provide essential nutrients, such as a vitamin, an essential mineral, a protein, an herb, or similar nutritional substance." ; rdfs:subClassOf obo:CHEBI_23888 . obo:PR_000044665 a rdfs:Class ; rdfs:label "glycine receptor protein" ; rdfs:comment "A ligand-gated ion channel protein that is a translation product of the human GLRA1, GLRA2, GLRA3, GLRA4, or GLRB genes, 1:1 orthologs thereof, or a semi-ortholog thereof." ; rdfs:subClassOf obo:PR_000044671 . obo:PR_P51148 a rdfs:Class ; rdfs:label "Ras-related protein Rab-5C (human)" ; rdfs:comment "A Ras-related protein Rab-5C that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000013635 , obo:PR_000029067 . a rdfs:Class ; rdfs:label "MYCOPHENOLIC ACID" ; rdfs:subClassOf . obo:NCBITaxon_1788457 a rdfs:Class ; rdfs:label "Hipposideros bat coronavirus BtCoV/3723" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:NCBITaxon_1159907 a rdfs:Class ; rdfs:label "White-eye coronavirus HKU16" ; rdfs:subClassOf obo:NCBITaxon_2509474 . obo:CHEBI_32556 a rdfs:Class ; rdfs:label "D-lysinate" ; rdfs:comment "An optically active form of lysinate having D-configuration." ; rdfs:subClassOf obo:CHEBI_32563 . obo:NCBITaxon_903611 a rdfs:Class ; rdfs:label "Kenya bat coronavirus BtKY73" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:CIDO_0020285 a rdfs:Class ; rdfs:label "SCoV-2 Detect IgG ELISA" ; rdfs:seeAlso ; rdfs:subClassOf obo:CIDO_0000454 . obo:VO_0005316 a rdfs:Class ; rdfs:label "Noora"@en ; rdfs:comment "A SARS-CoV-2 subunit vaccine by Bagheiat-allah University of Medical Sciences" ; rdfs:subClassOf obo:VO_0005269 . obo:CHEBI_22727 a rdfs:Class ; rdfs:label "benzopyran" ; rdfs:subClassOf obo:CHEBI_38104 , obo:CHEBI_38166 . obo:PR_000003534 a rdfs:Class ; rdfs:label "protein AATF" ; rdfs:comment "A protein that is a translation product of the human AATF gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:PR_Q9UQB9 a rdfs:Class ; rdfs:label "aurora kinase C (human)" ; rdfs:comment "An aurora kinase C that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000004518 , obo:PR_000029067 . obo:PR_000016059 a rdfs:Class ; rdfs:label "threonine--tRNA ligase, mitochondrial" ; rdfs:comment "A protein that is a translation product of the human TARS2 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:PR_Q8N766 a rdfs:Class ; rdfs:label "ER membrane protein complex subunit 1 (human)" ; rdfs:comment "An ER membrane protein complex subunit 1 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000029067 , obo:PR_000030474 . obo:CIDO_0000295 a rdfs:Class ; rdfs:label "symptomatic human female infected by SARS-CoV-2"@en ; rdfs:subClassOf obo:CIDO_0000291 . obo:NCBITaxon_2509492 a rdfs:Class ; rdfs:label "Luchacovirus" ; rdfs:subClassOf obo:NCBITaxon_693996 . obo:CHEBI_35570 a rdfs:Class ; rdfs:label "mancude organic heterobicyclic parent" ; rdfs:subClassOf obo:CHEBI_27171 , obo:CHEBI_35571 . obo:CHEBI_37164 a rdfs:Class ; rdfs:label "homopolysaccharide" ; rdfs:comment "Glycans composed of a single type of monosaccharide residue. They are named by replacing the ending '-ose' of the sugar by '-an'." ; rdfs:subClassOf obo:CHEBI_18154 . obo:OPMI_0000478 a rdfs:Class ; rdfs:label "birth-related time"@en ; rdfs:comment "time that is related to the birth" ; rdfs:subClassOf obo:BFO_0000038 . obo:CHEBI_33384 a rdfs:Class ; rdfs:label "L-serine zwitterion" ; rdfs:comment "A serine zwitterion obtained by transfer of a proton from the carboxy to the amino group of L-serine." ; rdfs:subClassOf obo:CHEBI_35243 . obo:CIDO_0000266 a rdfs:Class ; rdfs:label "microvascular angina"@en ; rdfs:comment "Angina (chest pain) with signs associated with decreased blood flow to heart tissue but with normal coronary arteries. Cardiac syndrome X is a historic term for microvascular angina. It is a heart disease that affects the heart’s smallest coronary artery blood vessels." ; rdfs:subClassOf obo:HP_0001681 . obo:GO_0042755 a rdfs:Class ; rdfs:label "eating behavior" ; rdfs:comment "The specific behavior of an organism relating to the intake of food, any substance (usually solid) that can be metabolized by an organism to give energy and build tissue." ; rdfs:subClassOf obo:GO_0007610 . obo:PR_000025848 a rdfs:Class ; rdfs:label "type I interferon" ; rdfs:comment "A protein that consists solely of an Interferon alpha/beta domain (Pfam:PF00143) and which binds to a specific cell surface receptor complex known as the IFN-alpha receptor (IFNAR), a heterodimer of IFNAR1 and IFNAR2 chains." ; rdfs:subClassOf obo:PR_000000001 . obo:PR_000010780 a rdfs:Class ; rdfs:label "muscle, skeletal receptor tyrosine-protein kinase" ; rdfs:comment "A protein that is a translation product of the human MUSK gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:PR_000011382 a rdfs:Class ; rdfs:label "neuronal pentraxin-1" ; rdfs:comment "A protein that is a translation product of the human NPTX1 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:CIDO_0020087 a rdfs:Class ; rdfs:label "Color SARS-CoV-2 RT-LAMP Diagnostic Assay DTC" ; rdfs:seeAlso ; rdfs:subClassOf obo:CIDO_0000454 . obo:VO_0005148 a rdfs:Class ; rdfs:label "SARS NDV-VF/S vaccine" ; rdfs:comment "A SARS-CoV recombinant vector vaccine that is made from the Newcastle disease virus from the lentogenic LaSota strain expressing SARS-CoV S protein." ; rdfs:subClassOf obo:VO_0012183 . obo:OBI_0002780 a rdfs:Class ; rdfs:label "nasal aspirate specimen" ; rdfs:comment "A specimen that is collected with a suctioning tube from the nasal cavity." ; rdfs:subClassOf obo:OBI_0002599 . obo:CIDO_0000005 a rdfs:Class ; rdfs:label "Human coronavirus 229E disease process"@en ; rdfs:subClassOf obo:CIDO_0000001 . obo:NCBITaxon_1788415 a rdfs:Class ; rdfs:label "Bat coronavirus MsBtCoV/4001-1" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:CHEBI_41402 a rdfs:Class ; rdfs:label "carboxymethyl group" ; rdfs:subClassOf obo:CHEBI_50325 . obo:DRON_00017006 a rdfs:Class ; rdfs:label "Rimantadine" ; rdfs:subClassOf obo:OBI_0000047 . obo:VO_0005340 a rdfs:Class ; rdfs:label "VB10.2129"@en ; rdfs:comment "A SARS-CoV-2 DNA vaccine developed by Vaccibody AS encoding the receptor-binding domain" ; rdfs:subClassOf obo:VO_0005203 . obo:CIDO_0020140 a rdfs:Class ; rdfs:label "Ezplex SARS-CoV-2 G Kit" ; rdfs:seeAlso ; rdfs:subClassOf obo:CIDO_0000454 . obo:IAO_0000579 a rdfs:Class ; rdfs:label "centrally registered identifier registry"@en ; rdfs:comment "A CRID registry is a dataset of CRID records, each consisting of a CRID symbol and additional information which was recorded in the dataset through a assigning a centrally registered identifier process."@en ; rdfs:subClassOf obo:IAO_0000027 . obo:GO_0043401 a rdfs:Class ; rdfs:label "steroid hormone mediated signaling pathway" ; rdfs:comment "The series of molecular signals mediated by a steroid hormone binding to a receptor." ; rdfs:subClassOf obo:GO_0007165 . a rdfs:Class ; rdfs:label "Triflupromazine [Chemical/Ingredient]" ; rdfs:subClassOf . obo:UBERON_0001052 a rdfs:Class ; rdfs:label "rectum" ; rdfs:comment "the terminal portion of the intestinal tube, terminating with the anus" ; rdfs:subClassOf obo:UBERON_0000465 . obo:NCBITaxon_2691595 a rdfs:Class ; rdfs:label "Rhinolophus affinis bat coronavirus HKU2-related" ; rdfs:subClassOf obo:NCBITaxon_2691594 . obo:NCBITaxon_247149 a rdfs:Class ; rdfs:label "SARS coronavirus WHU" ; rdfs:subClassOf obo:NCBITaxon_694009 . obo:CIDO_0000211 a rdfs:Class ; rdfs:label "SARS-CoV-2 inhibition of host response"@en ; rdfs:subClassOf obo:CIDO_0000193 . obo:CIDO_0020259 a rdfs:Class ; rdfs:label "Rapid COVID-19 IgM/IgG Combo Test Kit" ; rdfs:seeAlso ; rdfs:subClassOf obo:CIDO_0000454 . obo:UBERON_0000341 a rdfs:Class ; rdfs:label "throat" ; rdfs:comment "In anatomy, the throat is the anterior part of the neck, in front of the vertebral column. It consists of the pharynx and larynx. An important feature of the throat is the epiglottis, a flap which separates the esophagus from the trachea and prevents inhalation of food or drink. The throat contains various blood vessels, various pharyngeal muscles, the trachea (windpipe) and the esophagus. The hyoid bone and the clavicle are the only bones located in the throat of mammals. It is sometimes considered a synonym for fauces. [WP,unvetted]." ; rdfs:subClassOf obo:UBERON_0000465 , obo:UBERON_0010000 . obo:NCBITaxon_389134 a rdfs:Class ; rdfs:label "Bat coronavirus (BtCoV/A504/2005)" ; rdfs:subClassOf obo:NCBITaxon_389126 . a rdfs:Class ; rdfs:comment "An unconstrained type or object" . obo:CHEBI_13941 a rdfs:Class ; rdfs:label "carbamate" ; rdfs:subClassOf obo:CHEBI_37022 . obo:NCBITaxon_2042575 a rdfs:Class ; rdfs:label "Coronavirus PREDICT CoV-51" ; rdfs:subClassOf obo:NCBITaxon_696098 . obo:GO_1904950 a rdfs:Class ; rdfs:label "negative regulation of establishment of protein localization" ; rdfs:comment "Any process that stops, prevents or reduces the frequency, rate or extent of establishment of protein localization." ; rdfs:subClassOf obo:GO_0070201 , obo:GO_1903828 . obo:GO_0005249 a rdfs:Class ; rdfs:label "voltage-gated potassium channel activity" ; rdfs:comment "Enables the transmembrane transfer of a potassium ion by a voltage-gated channel. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded." ; rdfs:subClassOf obo:GO_0005267 , obo:GO_0022843 . obo:PR_000031226 a rdfs:Class ; rdfs:label "protein AAR2 homolog" ; rdfs:comment "A protein that is a translation product of the human AAR2 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:NCBITaxon_2520502 a rdfs:Class ; rdfs:label "Alphacoronavirus PLMg1" ; rdfs:subClassOf obo:NCBITaxon_2724758 . a rdfs:Class ; rdfs:label "Chlorpromazine [Chemical/Ingredient]" ; rdfs:subClassOf . obo:CIDO_0020036 a rdfs:Class ; rdfs:label "Atellica IM SARS-CoV-2 Total (COV2T)" ; rdfs:seeAlso ; rdfs:subClassOf obo:CIDO_0000454 . obo:CHEBI_28899 a rdfs:Class ; rdfs:label "nigeran" ; rdfs:subClassOf obo:CHEBI_25541 . a rdfs:Class ; rdfs:label "Hypertension [Disease/Finding]" ; rdfs:subClassOf . obo:OPMI_0000448 a rdfs:Class ; rdfs:label "inflammatory cytokine biomarker"@en ; rdfs:subClassOf obo:OPMI_0000447 . obo:APOLLO_SV_00000526 a rdfs:Class ; rdfs:label "scale-free network model"@en ; rdfs:comment "An algorithm that models some scale-free network."@en ; rdfs:subClassOf obo:IAO_0000064 . obo:GO_0080135 a rdfs:Class ; rdfs:label "regulation of cellular response to stress" ; rdfs:comment "Any process that modulates the frequency, rate or extent of a cellular response to stress. Cellular response to stress is a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating the organism is under stress. The stress is usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation)." ; rdfs:subClassOf obo:GO_0048583 , obo:GO_0050794 . obo:PR_P28223 a rdfs:Class ; rdfs:label "5-hydroxytryptamine receptor 2A (human)" ; rdfs:comment "A 5-hydroxytryptamine receptor 2A that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000001166 , obo:PR_000029067 . obo:CHEBI_77981 a rdfs:Class ; rdfs:label "vancomycin aglycone(1-)" ; rdfs:comment "A peptide anion that is the conjugate base of vancomycin aglycone and the major microspecies at pH 7.3 (according to Marvin v 6.2.0.)." ; rdfs:subClassOf obo:CHEBI_50525 , obo:CHEBI_60334 . obo:CHEBI_68472 a rdfs:Class ; rdfs:label "pyrimidine deoxyribonucleoside" ; rdfs:comment "A deoxyribonucleoside containing a pyrimidine base." ; rdfs:subClassOf obo:CHEBI_23636 , obo:CHEBI_26440 . obo:PR_000006079 a rdfs:Class ; rdfs:label "cytochrome b5 type B" ; rdfs:comment "A protein that is a translation product of the human CYB5B gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:OAE_0004580 a rdfs:Class ; rdfs:label "Level 5 TTS AE"@en ; rdfs:comment "most likely not a case of TTS" ; rdfs:subClassOf obo:OAE_0004540 . obo:PR_000030931 a rdfs:Class ; rdfs:label "asparagine--tRNA ligase, mitochondrial" ; rdfs:comment "A protein that is a translation product of the human NARS2 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:CHEBI_32551 a rdfs:Class ; rdfs:label "L-lysinium(1+)" ; rdfs:comment "An optically active form of lysinium having L-configuration." ; rdfs:subClassOf obo:CHEBI_32564 , obo:CHEBI_62031 . obo:NCBITaxon_745726 a rdfs:Class ; rdfs:label "Coronavirus N.noc/VM366/2008/NLD" ; rdfs:subClassOf obo:NCBITaxon_696098 . a rdfs:Class ; rdfs:label "Stimulation Large Intestine Fluid/Electrolyte Absorption [PE]" ; rdfs:subClassOf . obo:CHEBI_78543 a rdfs:Class ; rdfs:label "ponatinib" ; rdfs:comment "A benzamide obtained by the formal condensation of the carboxy group of 3-(imidazo[1,2-b]pyridazin-3-ylethynyl)-4-methylbenzoic acid with the anilino group of 4-[(4-methylpiperazin-1-yl)methyl]-3-(trifluoromethyl)aniline." ; rdfs:subClassOf obo:CHEBI_22702 , obo:CHEBI_46920 , obo:CHEBI_48382 , obo:CHEBI_73474 , obo:CHEBI_83565 . obo:NCBITaxon_2042550 a rdfs:Class ; rdfs:label "Coronavirus PREDICT CoV-23" ; rdfs:subClassOf obo:NCBITaxon_696098 . obo:NCBITaxon_2691587 a rdfs:Class ; rdfs:label "Miniopterus pusillus bat coronavirus HKU8-related" ; rdfs:subClassOf obo:NCBITaxon_2691586 . obo:CHEBI_38298 a rdfs:Class ; rdfs:label "benzodioxoles" ; rdfs:subClassOf obo:CHEBI_27171 , obo:CHEBI_38104 . obo:CIDO_0001226 a rdfs:Class ; rdfs:label "Multiple Real-Time PCR Kit for Detection of 2019-nCoV. (Hangzhou DIAN Biotechnology Co., Ltd.)" ; rdfs:comment "Manufacturor: Hangzhou DIAN Biotechnology Co., Ltd. 杭州迪安生物技术有限公司" ; rdfs:subClassOf obo:CIDO_0000021 . obo:HP_0001635 a rdfs:Class ; rdfs:label "Congestive heart failure" ; rdfs:comment "The presence of an abnormality of cardiac function that is responsible for the failure of the heart to pump blood at a rate that is commensurate with the needs of the tissues or a state in which abnormally elevated filling pressures are required for the heart to do so. Heart failure is frequently related to a defect in myocardial contraction." ; rdfs:subClassOf obo:HP_0011025 . obo:PR_000010188 a rdfs:Class ; rdfs:label "MAP/microtubule affinity-regulating kinase 3" ; rdfs:comment "A protein that is a translation product of the human MARK3 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:DRON_00027247 a rdfs:Class ; rdfs:label "interferon beta-1b Injectable Solution" ; rdfs:subClassOf obo:DRON_00000020 . obo:PR_P50993 a rdfs:Class ; rdfs:label "sodium/potassium-transporting ATPase subunit alpha-2 (human)" ; rdfs:comment "A sodium/potassium-transporting ATPase subunit alpha-2 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000004436 , obo:PR_000029067 . obo:PR_000015622 a rdfs:Class ; rdfs:label "tyrosine-protein kinase Srms" ; rdfs:comment "A proto-oncogene SRC-like tyrosine-protein kinase that is a translation product of the human SRMS gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000002997 . obo:IAO_0000005 a rdfs:Class ; rdfs:label "objective specification"@en ; rdfs:comment "A directive information entity that describes an intended process endpoint. When part of a plan specification the concretization is realized in a planned process in which the bearer tries to effect the world so that the process endpoint is achieved."@en ; rdfs:subClassOf obo:IAO_0000033 . obo:OPMI_0000556 a rdfs:Class ; rdfs:label "device exposure temporal region"@en ; rdfs:comment "the date or time on which a device exposure occurs" ; rdfs:subClassOf obo:BFO_0000148 . obo:NCBITaxon_745736 a rdfs:Class ; rdfs:label "Coronavirus M.dau/VM303/2008/NLD" ; rdfs:subClassOf obo:NCBITaxon_696098 . obo:NCBITaxon_1679894 a rdfs:Class ; rdfs:label "Coronavirus RCoV/D_RMU10_1989/Myo_gla/GER/2010" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:PR_000012099 a rdfs:Class ; rdfs:label "serine/threonine-protein kinase OSR1" ; rdfs:comment "A protein that is a translation product of the human OXSR1 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:OAE_0000476 a rdfs:Class ; rdfs:label "immune system AE" ; rdfs:comment "an AE that occurs in immune system." ; rdfs:subClassOf obo:OAE_0000001 . a rdfs:Class ; rdfs:label "THIOTHIXENE" ; rdfs:subClassOf . a rdfs:Class ; rdfs:label "Quinolines [Chemical/Ingredient]" ; rdfs:subClassOf . obo:NCBITaxon_8509 a rdfs:Class ; rdfs:label "Squamata" ; rdfs:subClassOf obo:NCBITaxon_8504 . obo:OBI_2000017 a rdfs:Class ; rdfs:label "reticulocyte specimen" ; rdfs:comment "A specimen that is derived from some reticulocytes " ; rdfs:subClassOf obo:OBI_0002599 . obo:CIDO_0000723 a rdfs:Class ; rdfs:label "S2625F in SARS-CoV-2 pp1a protein"@en ; rdfs:comment "An AA mutation or AA variant that has mutated an amino acid at position 1554 into a phenylalanine in pp1a." ; rdfs:subClassOf obo:CIDO_0001074 . obo:CHEBI_35881 a rdfs:Class ; rdfs:label "pnictogen hydride" ; rdfs:subClassOf obo:CHEBI_33242 , obo:CHEBI_33302 . obo:PR_P08172 a rdfs:Class ; rdfs:label "muscarinic acetylcholine receptor M2 (human)" ; rdfs:comment "A muscarinic acetylcholine receptor M2 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000001614 , obo:PR_000029067 . obo:OBI_0000862 a rdfs:Class ; rdfs:label "nuclear RNA extract" ; rdfs:comment "A RNA extract that is the output of an extraction process in which RNA molecules found in the nucleus, including mRNA precursors (pre-mRNA), are extracted." ; rdfs:subClassOf obo:OBI_0000880 . obo:GO_0016070 a rdfs:Class ; rdfs:label "RNA metabolic process" ; rdfs:comment "The cellular chemical reactions and pathways involving RNA, ribonucleic acid, one of the two main type of nucleic acid, consisting of a long, unbranched macromolecule formed from ribonucleotides joined in 3',5'-phosphodiester linkage." ; rdfs:subClassOf obo:GO_0090304 . obo:NCBITaxon_931902 a rdfs:Class ; rdfs:label "Alphacoronavirus Eptesicus fuscus/Appalachian Ridge/P1-C412/IT/USA/2009" ; rdfs:subClassOf obo:NCBITaxon_366617 . obo:GO_0070848 a rdfs:Class ; rdfs:label "response to growth factor" ; rdfs:comment "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a growth factor stimulus." ; rdfs:subClassOf obo:GO_0010033 . a rdfs:Class ; rdfs:label "Encephalitis [Disease/Finding]" ; rdfs:subClassOf , . obo:NCBITaxon_996629 a rdfs:Class ; rdfs:label "Bat coronavirus M.ful/Japan/02/2010" ; rdfs:subClassOf obo:NCBITaxon_366617 . obo:NCBITaxon_305409 a rdfs:Class ; rdfs:label "SARS coronavirus B033" ; rdfs:subClassOf obo:NCBITaxon_694009 . obo:CIDO_0000738 a rdfs:Class ; rdfs:label "T76I in SARS-CoV-2 S protein"@en ; rdfs:comment "An AA variant that has mutated an amino acid at position 76 into isoleucine in S protein." ; rdfs:subClassOf obo:CIDO_0000594 . obo:CHEBI_33232 a rdfs:Class ; rdfs:label "application" ; rdfs:comment "Intended use of the molecular entity or part thereof by humans." ; rdfs:subClassOf obo:CHEBI_50906 . obo:CHEBI_38180 a rdfs:Class ; rdfs:label "polycyclic heteroarene" ; rdfs:subClassOf obo:CHEBI_33833 . obo:CIDO_0000696 a rdfs:Class ; rdfs:label "S982A in SARS-CoV-2 S protein" ; rdfs:comment "An AA mutation or AA variant that has mutated an amino acid at position 982 into a alanine in S protein." ; rdfs:subClassOf obo:CIDO_0001161 . obo:CIDO_0020306 a rdfs:Class ; rdfs:label "Tell Me Fast Novel Coronavirus (COVID-19) IgG/IgM Antibody Test" ; rdfs:seeAlso ; rdfs:subClassOf obo:CIDO_0000454 . obo:PR_P0C6X7 a rdfs:Class ; rdfs:label "Replicase polyprotein 1ab (SARS-CoV)" ; rdfs:comment "A protein from human SARS coronavirus (SARS-CoV)." ; rdfs:subClassOf obo:PR_000000001 . obo:CHEBI_75772 a rdfs:Class ; rdfs:label "Saccharomyces cerevisiae metabolite" ; rdfs:comment "Any fungal metabolite produced during a metabolic reaction in Baker's yeast (Saccharomyces cerevisiae)." ; rdfs:subClassOf obo:CHEBI_76946 . obo:NCBITaxon_262338 a rdfs:Class ; rdfs:label "SARS coronavirus GD03T0013" ; rdfs:subClassOf obo:NCBITaxon_694009 . a rdfs:Class ; rdfs:label "Depressive Disorder [Disease/Finding]" ; rdfs:subClassOf . obo:CHEBI_32873 a rdfs:Class ; rdfs:label "prolino group" ; rdfs:subClassOf obo:CHEBI_24433 . obo:CHEBI_53289 a rdfs:Class ; rdfs:label "donepezil" ; rdfs:comment "A racemate comprising equimolar amounts of (R)- and (S)-donepezil. A centrally acting reversible acetylcholinesterase inhibitor, its main therapeutic use is in the treatment of Alzheimer's disease where it is used to increase cortical acetylcholine." ; rdfs:subClassOf obo:CHEBI_60911 . a rdfs:Class ; rdfs:label "Joint Diseases [Disease/Finding]" ; rdfs:subClassOf . a rdfs:Class ; rdfs:label "Mycoplasma Infections [Disease/Finding]" ; rdfs:subClassOf . obo:PR_000013318 a rdfs:Class ; rdfs:label "serine protease 1" ; rdfs:comment "A trypsin that is a translation product of the human PRSS1 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000027795 . obo:CHEBI_63113 a rdfs:Class ; rdfs:label "fingolimod(1+)" ; rdfs:comment "An organic cation that is the conjugate acid of fingolimod." ; rdfs:subClassOf obo:CHEBI_25697 , obo:CHEBI_35274 . obo:NCBITaxon_745737 a rdfs:Class ; rdfs:label "Coronavirus M.dau/VM361/2008/NLD" ; rdfs:subClassOf obo:NCBITaxon_696098 . obo:NCBITaxon_27592 a rdfs:Class ; rdfs:label "Bovinae" ; rdfs:subClassOf obo:NCBITaxon_9895 . obo:CIDO_0000216 a rdfs:Class ; rdfs:label "SARS-CoV-2 M protein synthesis"@en ; rdfs:subClassOf obo:CIDO_0000213 . obo:CHEBI_3546 a rdfs:Class ; rdfs:label "cepharanthine" ; rdfs:comment "A bisbenzylisoquinoline alkaloid from tubers of Stephania; stimulates recovery of immunologic function in lymphatic system after administration of antineoplastic agents or x-irradiation." ; rdfs:subClassOf obo:CHEBI_133004 , obo:CHEBI_24922 . obo:CHEBI_33832 a rdfs:Class ; rdfs:label "organic cyclic compound" ; rdfs:comment "Any organic molecule that consists of atoms connected in the form of a ring." ; rdfs:subClassOf obo:CHEBI_33595 , obo:CHEBI_50860 , obo:CHEBI_72695 . obo:NCBITaxon_442736 a rdfs:Class ; rdfs:label "Bat SARS coronavirus HKU3" ; rdfs:subClassOf obo:NCBITaxon_694009 . obo:NCBITaxon_2042545 a rdfs:Class ; rdfs:label "Coronavirus PREDICT CoV-19" ; rdfs:subClassOf obo:NCBITaxon_696098 . obo:NCBITaxon_864622 a rdfs:Class ; rdfs:label "Bat coronavirus 2B BR98-19/BGR/2008" ; rdfs:subClassOf obo:NCBITaxon_455415 . obo:PR_000001357 a rdfs:Class ; rdfs:label "intercellular adhesion molecule 1/3" ; rdfs:comment "A protein with a core domain architecture consisting of an Intercellular adhesion molecule (ICAM), N-terminal domain (Pfam:PF03921), a type of Ig-like domain, and four copies of the Immunoglobulin domain (Pfam:PF00047), most of which are not detected by Pfam." ; rdfs:subClassOf obo:PR_000000001 . obo:NCBITaxon_2042539 a rdfs:Class ; rdfs:label "Coronavirus PREDICT CoV-12" ; rdfs:subClassOf obo:NCBITaxon_366617 . obo:OBI_0200000 a rdfs:Class ; rdfs:label "data transformation"@en ; rdfs:comment "A planned process that produces output data from input data."@en ; rdfs:subClassOf obo:OBI_0000011 . obo:CHEBI_18282 a rdfs:Class ; rdfs:label "nucleobase" ; rdfs:comment "That part of DNA or RNA that may be involved in pairing." ; rdfs:subClassOf obo:CHEBI_38101 . obo:CIDO_0020100 a rdfs:Class ; rdfs:label "COVID-SeroKlir, Kantaro Semi-Quantitative SARS-CoV-2 IgG Antibody Kit" ; rdfs:seeAlso ; rdfs:subClassOf obo:CIDO_0000454 . obo:PR_000014873 a rdfs:Class ; rdfs:label "nucleotide exchange factor SIL1" ; rdfs:comment "A protein that is a translation product of the human SIL1 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . a rdfs:Class ; rdfs:label "H [Preparations]" ; rdfs:subClassOf . a rdfs:Class ; rdfs:label "Recombinant Proteins [Chemical/Ingredient]" ; rdfs:subClassOf . obo:NCBITaxon_293936 a rdfs:Class ; rdfs:label "SARS coronavirus PC4-227" ; rdfs:subClassOf obo:NCBITaxon_694009 . obo:PR_P48551 a rdfs:Class ; rdfs:label "interferon alpha/beta receptor 2 (human)" ; rdfs:comment "An interferon alpha/beta receptor 2 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000008923 , obo:PR_000029067 . obo:PR_Q9NYK1 a rdfs:Class ; rdfs:label "Toll-like receptor 7 (human)" ; rdfs:comment "A Toll-like receptor 7 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000001158 , obo:PR_000029067 . obo:UBERON_0002369 a rdfs:Class ; rdfs:label "adrenal gland" ; rdfs:comment "Either of a pair of complex endocrine organs near the anterior medial border of the kidney consisting of a mesodermal cortex that produces glucocorticoid, mineralocorticoid, and androgenic hormones and an ectodermal medulla that produces epinephrine and norepinephrine[BTO]." ; rdfs:subClassOf obo:UBERON_0000465 . obo:PR_Q8IZ52 a rdfs:Class ; rdfs:label "chondroitin sulfate synthase 2 (human)" ; rdfs:comment "A chondroitin sulfate synthase 2 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000005448 , obo:PR_000029067 . obo:VO_0005398 a rdfs:Class ; rdfs:label "MIPSCo-mRNA-RBD-1"@en ; rdfs:comment "A SARS-CoV-2 RNA vaccine by the University of Melbourne." ; rdfs:subClassOf obo:VO_0005198 . obo:NCBITaxon_441980 a rdfs:Class ; rdfs:label "Flying squirrel coronavirus Guangxi/E001/2006" ; rdfs:subClassOf obo:NCBITaxon_441985 . obo:NCBITaxon_231515 a rdfs:Class ; rdfs:label "Civet SARS CoV SZ16/2003" ; rdfs:subClassOf obo:NCBITaxon_694009 . obo:NCBITaxon_1788468 a rdfs:Class ; rdfs:label "Miniopterus bat coronavirus BtCoV/3760-2" ; rdfs:subClassOf obo:NCBITaxon_2664420 . a rdfs:Class ; rdfs:label "Lupus Erythematosus, Cutaneous [Disease/Finding]" ; rdfs:subClassOf , . obo:PR_Q8WTV0 a rdfs:Class ; rdfs:label "scavenger receptor class B member 1 (human)" ; rdfs:comment "A scavenger receptor class B member 1 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000014493 , obo:PR_000029067 . obo:CHEBI_43176 a rdfs:Class ; rdfs:label "hydroxy group" ; rdfs:subClassOf obo:CHEBI_33246 . obo:NCBITaxon_136187 a rdfs:Class ; rdfs:label "Equine coronavirus" ; rdfs:subClassOf obo:NCBITaxon_694003 . obo:GO_0051384 a rdfs:Class ; rdfs:label "response to glucocorticoid" ; rdfs:comment "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glucocorticoid stimulus. Glucocorticoids are hormonal C21 corticosteroids synthesized from cholesterol with the ability to bind with the cortisol receptor and trigger similar effects. Glucocorticoids act primarily on carbohydrate and protein metabolism, and have anti-inflammatory effects." ; rdfs:subClassOf obo:GO_0048545 . obo:CHEBI_86478 a rdfs:Class ; rdfs:label "antibiotic antifungal agent" ; rdfs:comment "Heteroorganic entities that are microbial metabolites (or compounds derived from them) which have significant antifungal properties." ; rdfs:subClassOf obo:CHEBI_33285 . a rdfs:Class ; rdfs:label "Respiratory Tract Diseases [Disease/Finding]" ; rdfs:subClassOf . obo:PR_Q6UUV7 a rdfs:Class ; rdfs:label "CREB-regulated transcription coactivator 3 (human)" ; rdfs:comment "A CREB-regulated transcription coactivator 3 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000005903 , obo:PR_000029067 . obo:PR_000010132 a rdfs:Class ; rdfs:label "mitogen-activated protein kinase kinase kinase 13" ; rdfs:comment "A protein that is a translation product of the human MAP3K13 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:NCBITaxon_497936 a rdfs:Class ; rdfs:label "Bat coronavirus M.das/Germany/D3.10/2007" ; rdfs:subClassOf obo:NCBITaxon_366617 . obo:PR_O00519 a rdfs:Class ; rdfs:label "fatty-acid amide hydrolase 1 (human)" ; rdfs:comment "A fatty-acid amide hydrolase 1 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000007305 , obo:PR_000029067 . obo:CHEBI_27617 a rdfs:Class ; rdfs:label "monensin A" ; rdfs:comment "A spiroketal, monensin A is the major component of monensin, a mixture of antibiotic substances produced by Streptomyces cinnamonensis. An antiprotozoal, it is used as the sodium salt as a feed additive for the prevention of coccidiosis in poultry and as a growth promoter in cattle." ; rdfs:subClassOf obo:CHEBI_25384 , obo:CHEBI_26179 , obo:CHEBI_59780 , obo:CHEBI_72600 . obo:NCBITaxon_1159904 a rdfs:Class ; rdfs:label "Night heron coronavirus HKU19" ; rdfs:subClassOf obo:NCBITaxon_2509485 . obo:CHEBI_65256 a rdfs:Class ; rdfs:label "antimicrobial food preservative" ; rdfs:comment "A food preservative which prevents decomposition of food by preventing the growth of fungi or bacteria. In European countries, E-numbers for permitted food preservatives are from E200 to E299, divided into sorbates (E200-209), benzoates (E210-219), sulfites (E220-229), phenols and formates (E230-239), nitrates (E240-259), acetates (E260-269), lactates (E270-279), propionates (E280-289) and others (E290-299)." ; rdfs:subClassOf obo:CHEBI_33281 , obo:CHEBI_65255 . obo:CHEBI_35507 a rdfs:Class ; rdfs:label "natural product fundamental parent" ; rdfs:subClassOf obo:CHEBI_33245 . obo:NCBITaxon_1788479 a rdfs:Class ; rdfs:label "Miniopterus bat coronavirus BtCoV/4056-1" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:NCBITaxon_1289548 a rdfs:Class ; rdfs:label "Coronavirus Mex_CoV-3" ; rdfs:subClassOf obo:NCBITaxon_366617 . obo:NCBITaxon_239241 a rdfs:Class ; rdfs:label "SARS coronavirus CUHK-AG01" ; rdfs:subClassOf obo:NCBITaxon_694009 . obo:CHEBI_26666 a rdfs:Class ; rdfs:label "short-chain fatty acid" ; rdfs:comment "An aliphatic monocarboxylic acid with a chain length of less than C6. If any non-hydrocarbon substituent is present, the compound is not normally regarded as a short-chain fatty acid." ; rdfs:subClassOf obo:CHEBI_35366 . obo:PR_000009445 a rdfs:Class ; rdfs:label "Kremen protein 1" ; rdfs:comment "A protein that is a translation product of the human KREMEN1 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:CIDO_0020263 a rdfs:Class ; rdfs:label "Real-Time Fluorescent RT-PCR Kit for Detecting SARS-CoV-2" ; rdfs:seeAlso ; rdfs:subClassOf obo:CIDO_0000454 . obo:HP_0001626 a rdfs:Class ; rdfs:label "Abnormality of the cardiovascular system" ; rdfs:comment "Any abnormality of the cardiovascular system." ; rdfs:subClassOf obo:HP_0000118 . obo:CIDO_0000778 a rdfs:Class ; rdfs:label "SARS-CoV2 N protein binding to human DDX21" ; rdfs:comment "SARS-CoV2 N protein binding to human DDX21, as evidented by an affinity-purification mass spectrometry experiment" ; rdfs:subClassOf obo:CIDO_0000056 . obo:PR_Q9NP72 a rdfs:Class ; rdfs:label "Ras-related protein Rab-18 (human)" ; rdfs:comment "A Ras-related protein Rab-18 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000013589 , obo:PR_000029067 . obo:PR_000002063 a rdfs:Class ; rdfs:label "macrophage-stimulating protein receptor" ; rdfs:comment "An HGF/MSP receptor type tyrosine-protein kinase that is a translation product of the human MST1R gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000001816 . obo:HP_0011691 a rdfs:Class ; rdfs:label "Supraventricular tachycardia with a concealed accessory pathway on the left free wall" ; rdfs:subClassOf obo:HP_0011689 . obo:TRANS_0000000 a rdfs:Class ; rdfs:label "transmission process" ; rdfs:comment "A process that is the means during which the pathogen is transmitted directly or indirectly from its natural reservoir, a susceptible host or source to a new host." ; rdfs:subClassOf obo:BFO_0000015 . obo:NCBITaxon_228407 a rdfs:Class ; rdfs:label "SARS coronavirus BJ01" ; rdfs:subClassOf obo:NCBITaxon_694009 . obo:CHEBI_53290 a rdfs:Class ; rdfs:label "(S)-donepezil" ; rdfs:comment "A 2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimethoxyindan-1-one that has S configuration." ; rdfs:subClassOf obo:CHEBI_145499 . obo:VO_0005417 a rdfs:Class ; rdfs:label "Omicron COVID-19 inactivated vaccine by China National Biotec Group Company Limited"@en ; rdfs:comment "A SARS-CoV-2 inactivated vaccine developed by China National Biotec Group Company Limited" ; rdfs:subClassOf obo:VO_0005201 . obo:PR_000016959 a rdfs:Class ; rdfs:label "ubiquitin-associated protein 2" ; rdfs:comment "A protein that is a translation product of the human UBAP2 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:GO_0007271 a rdfs:Class ; rdfs:label "synaptic transmission, cholinergic" ; rdfs:comment "The vesicular release of acetylcholine from a presynapse, across a chemical synapse, the subsequent activation of dopamine receptors at the postsynapse of a target cell (neuron, muscle, or secretory cell) and the effects of this activation on the postsynaptic membrane potential and ionic composition of the postsynaptic cytosol. This process encompasses both spontaneous and evoked release of neurotransmitter and all parts of synaptic vesicle exocytosis. Evoked transmission starts with the arrival of an action potential at the presynapse." ; rdfs:subClassOf obo:GO_0007268 . obo:CHEBI_29534 a rdfs:Class ; rdfs:label "avermectin B1a" ; rdfs:subClassOf obo:CHEBI_50344 . obo:IDO_0000599 a rdfs:Class ; rdfs:label "host living in endemic area"@en ; rdfs:comment "A host exposure to environment with infectious agent where the environment is an area in which an infectious agent is endemic"@en ; rdfs:subClassOf obo:IDO_0000597 . obo:CHEBI_47018 a rdfs:Class ; rdfs:label "monohydroxytetrahydrofuran" ; rdfs:subClassOf obo:CHEBI_47017 . obo:CHEBI_16867 a rdfs:Class ; rdfs:label "D-methionine" ; rdfs:comment "An optically active form of methionine having D-configuration." ; rdfs:subClassOf obo:CHEBI_16733 , obo:CHEBI_16811 . obo:OBI_0002744 a rdfs:Class ; rdfs:label "molecular label"@en ; rdfs:comment "A molecular reagent intended to associate with some molecular target to serve as a proxy for the presence, abundance, or location of this target in a detection of molecular label assay"@en ; rdfs:subClassOf obo:CHEBI_23367 , obo:OBI_0001879 . obo:CHEBI_76713 a rdfs:Class ; rdfs:label "EC 4.3.* (C-N lyase) inhibitor" ; rdfs:comment "A lyase inhibitor which inhibits the action of a C-N lyase (EC 4.3.*.*)." ; rdfs:subClassOf obo:CHEBI_76710 . obo:UBERON_0005921 a rdfs:Class ; rdfs:label "middle nasal concha" ; rdfs:comment "The medial surface of the labyrinth of ethmoid consists of a thin lamella, which descends from the under surface of the cribriform plate, and ends below in a free, convoluted margin, the middle nasal concha. It is rough, and marked above by numerous grooves, directed nearly vertically downward from the cribriform plate; they lodge branches of the olfactory nerves, which are distributed to the mucous membrane covering the superior nasal concha." ; rdfs:subClassOf obo:UBERON_0000465 . obo:CIDO_0020337 a rdfs:Class ; rdfs:label "Xpert Omni SARS-CoV-2" ; rdfs:seeAlso ; rdfs:subClassOf obo:CIDO_0000454 . obo:PR_000001178 a rdfs:Class ; rdfs:label "D(3) dopamine receptor" ; rdfs:comment "A D(2)-like dopamine receptor that is a translation product of the human DRD3 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000001108 . obo:PR_000012877 a rdfs:Class ; rdfs:label "procollagen-lysine,2-oxoglutarate 5-dioxygenase 2" ; rdfs:comment "A protein that is a translation product of the human PLOD2 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:OBI_0100066 a rdfs:Class ; rdfs:label "organ section"@en ; rdfs:comment "A processed material which derives from an organ and results from a process of dissection or histological sample preparation a portion(formerly an organ section is portion of an organ removed from the context of the organ)"@en ; rdfs:subClassOf obo:OBI_0000047 . obo:PR_000014794 a rdfs:Class ; rdfs:label "serine/threonine-protein kinase Sgk3" ; rdfs:comment "A protein that is a translation product of the human SGK3 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:NCBITaxon_903637 a rdfs:Class ; rdfs:label "Kenya bat coronavirus BtKY99" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:CHEBI_8688 a rdfs:Class ; rdfs:label "Pyrvinium pamoate" ; rdfs:subClassOf obo:CHEBI_25483 . obo:VO_0005126 a rdfs:Class ; rdfs:label "recombinant SARS DNA spike protein vaccine" ; rdfs:comment "A SARS DNA vaccine made from rDNA-expressed ectodomain of the S protein." ; rdfs:subClassOf obo:VO_0012183 . obo:NCBITaxon_389254 a rdfs:Class ; rdfs:label "Bat coronavirus A515/2005" ; rdfs:subClassOf obo:NCBITaxon_366617 . a rdfs:Class ; rdfs:label "Stomach Diseases [Disease/Finding]" ; rdfs:subClassOf . obo:PR_P30405 a rdfs:Class ; rdfs:label "peptidyl-prolyl cis-trans isomerase F, mitochondrial (human)" ; rdfs:comment "A peptidyl-prolyl cis-trans isomerase F, mitochondrial that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000013080 , obo:PR_000029067 . a rdfs:Class ; rdfs:label "Sarcoma [Disease/Finding]" ; rdfs:subClassOf . obo:CHEBI_33261 a rdfs:Class ; rdfs:label "organosulfur compound" ; rdfs:comment "An organosulfur compound is a compound containing at least one carbon-sulfur bond." ; rdfs:subClassOf obo:CHEBI_26835 , obo:CHEBI_36962 . obo:CHEBI_24396 a rdfs:Class ; rdfs:label "glycopeptide" ; rdfs:comment "Any carbohydrate derivative that consists of glycan moieties covalently attached to the side chains of the amino acid residues that constitute the peptide." ; rdfs:subClassOf obo:CHEBI_16670 , obo:CHEBI_63299 . obo:NCBITaxon_1346316 a rdfs:Class ; rdfs:label "Betacoronavirus BtCoV/Rhi_hip/Slo54/SLO/2009" ; rdfs:subClassOf obo:NCBITaxon_696098 . obo:CHEBI_83156 a rdfs:Class ; rdfs:label "EC 6.2.1.* (acid-thiol ligase) inhibitor" ; rdfs:comment "An EC 6.2.* (C-S bond-forming ligase) inhibitor that interferes with the action of an acid-thiol ligase inhibitor (EC 6.2.1.*)." ; rdfs:subClassOf obo:CHEBI_76707 . obo:PR_000013428 a rdfs:Class ; rdfs:label "prostaglandin G/H synthase 2" ; rdfs:comment "A protein that is a translation product of the human PTGS2 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:PR_000003136 a rdfs:Class ; rdfs:label "subtilisin/kexin-type proprotein convertase" ; rdfs:comment "Category=family." ; rdfs:subClassOf obo:PR_000000001 . obo:CHEBI_17996 a rdfs:Class ; rdfs:label "chloride" ; rdfs:comment "A halide anion formed when chlorine picks up an electron to form an an anion." ; rdfs:subClassOf obo:CHEBI_16042 , obo:CHEBI_33432 . obo:HP_0011704 a rdfs:Class ; rdfs:label "Sick sinus syndrome" ; rdfs:comment "An abnormality involving the generation of the action potential by the sinus node and is characterized by an atrial rate inappropriate for physiological requirements. Manifestations include severe sinus bradycardia, sinus pauses or arrest, sinus node exit block, chronic atrial tachyarrhythmias, alternating periods of atrial bradyarrhythmias and tachyarrhythmias, and inappropriate responses of heart rate during exercise or stress." ; rdfs:subClassOf obo:HP_0011702 , obo:HP_0012722 . obo:NCBITaxon_1911231 a rdfs:Class ; rdfs:label "Deltacoronavirus sp." ; rdfs:subClassOf obo:NCBITaxon_1232736 . obo:CIDO_0020301 a rdfs:Class ; rdfs:label "Stanford SARS-CoV-2 assay" ; rdfs:seeAlso ; rdfs:subClassOf obo:CIDO_0000454 . obo:PR_Q9UJZ1 a rdfs:Class ; rdfs:label "stomatin-like protein 2, mitochondrial (human)" ; rdfs:comment "A stomatin-like protein 2 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000015765 , obo:PR_000029067 . obo:PR_P08908 a rdfs:Class ; rdfs:label "5-hydroxytryptamine receptor 1A (human)" ; rdfs:comment "A 5-hydroxytryptamine receptor 1A that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000001161 , obo:PR_000029067 . obo:NCBITaxon_9835 a rdfs:Class ; rdfs:label "Camelidae" ; rdfs:subClassOf obo:NCBITaxon_9834 . obo:CHEBI_50344 a rdfs:Class ; rdfs:label "avermectin" ; rdfs:comment "Any of the macrolides obtained as fermentation products from the bacterium Streptomyces avermitilis and consisting of a 16-membered macrocyclic backbone that is fused both benzofuran and spiroketal functions and contains a disaccharide substituent. They have significant anthelmintic and insecticidal properties." ; rdfs:subClassOf obo:CHEBI_25106 , obo:CHEBI_59779 . obo:NCBITaxon_797376 a rdfs:Class ; rdfs:label "Bat coronavirus TM5" ; rdfs:subClassOf obo:NCBITaxon_366617 . obo:OAE_0000946 a rdfs:Class ; rdfs:label "feeling hot AE" ; rdfs:comment "Feeling hot AE is a feeling abnormal AE that a patient feels hot. " ; rdfs:subClassOf obo:OAE_0000945 . obo:CHEBI_87071 a rdfs:Class ; rdfs:label "conazole antifungal drug" ; rdfs:comment "Any conazole antifungal agent that has been used for the treatment of fungal infections in animals or humans." ; rdfs:subClassOf obo:CHEBI_68452 , obo:CHEBI_86323 . obo:CHEBI_32697 a rdfs:Class ; rdfs:label "argininium(2+)" ; rdfs:subClassOf obo:CHEBI_33719 . obo:NCBITaxon_1076418 a rdfs:Class ; rdfs:label "Alphacoronavirus N.las/D/Spain/2007" ; rdfs:subClassOf obo:NCBITaxon_366617 . obo:PR_Q9HBH9 a rdfs:Class ; rdfs:label "MAP kinase-interacting serine/threonine-protein kinase 2 (human)" ; rdfs:comment "A MAP kinase-interacting serine/threonine-protein kinase 2 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000010430 , obo:PR_000029067 . obo:NCBITaxon_996612 a rdfs:Class ; rdfs:label "Bat coronavirus N78-10/Germany/2008" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:PR_000010319 a rdfs:Class ; rdfs:label "maternal embryonic leucine zipper kinase" ; rdfs:comment "A protein that is a translation product of the human MELK gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:CHEBI_25477 a rdfs:Class ; rdfs:label "naphthalenes" ; rdfs:comment "Any benzenoid aromatic compound having a skeleton composed of two ortho-fused benzene rings." ; rdfs:subClassOf obo:CHEBI_33836 , obo:CHEBI_36785 . obo:CHEBI_16914 a rdfs:Class ; rdfs:label "salicylic acid" ; rdfs:comment "A monohydroxybenzoic acid that is benzoic acid with a hydroxy group at the ortho position. It is obtained from the bark of the white willow and wintergreen leaves." ; rdfs:subClassOf obo:CHEBI_25389 . obo:CHEBI_139590 a rdfs:Class ; rdfs:label "primary alpha-hydroxy ketone" ; rdfs:comment "An alpha-hydroxy ketone in which the carbonyl group and the hydroxy group are linked by a -CH2 (methylene) group." ; rdfs:subClassOf obo:CHEBI_139588 , obo:CHEBI_15734 . obo:CIDO_0000820 a rdfs:Class ; rdfs:label "SARS-CoV2 nsp12 protein binding to human USP54" ; rdfs:comment "SARS-CoV2 nsp12 protein binding to human USP54, as evidented by an affinity-purification mass spectrometry experiment" ; rdfs:subClassOf obo:CIDO_0000057 . obo:CHEBI_25810 a rdfs:Class ; rdfs:label "oxopurine" ; rdfs:subClassOf obo:CHEBI_26401 . obo:NCBITaxon_679171 a rdfs:Class ; rdfs:label "Harbor seal coronavirus 1" ; rdfs:subClassOf obo:NCBITaxon_366617 . obo:PR_Q8N6S5 a rdfs:Class ; rdfs:label "ADP-ribosylation factor-like protein 6-interacting protein 6 (human)" ; rdfs:comment "An ADP-ribosylation factor-like protein 6-interacting protein 6 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000004294 , obo:PR_000029067 . obo:CHEBI_35106 a rdfs:Class ; rdfs:label "nitrogen hydride" ; rdfs:subClassOf obo:CHEBI_35881 , obo:CHEBI_51143 . obo:CHEBI_26167 a rdfs:Class ; rdfs:label "polar amino acid" ; rdfs:comment "Any amino acid whose side chain is capable of forming one or more hydrogen bonds." ; rdfs:subClassOf obo:CHEBI_33709 . obo:VO_0005130 a rdfs:Class ; rdfs:label "VRP-MERS-N vaccine" ; rdfs:comment "A MERS recombinant vector made from Venezuelan equine encephalitis replicons bearing epitopes of N protein from MERS. Crosslisted as SARS vaccine (VIOLINID:5754). Efficacy higher intranasally than subcutaneously." ; rdfs:subClassOf obo:VO_0004900 . obo:CHEBI_33693 a rdfs:Class ; rdfs:label "oxygen hydride" ; rdfs:subClassOf obo:CHEBI_36902 . obo:NCBITaxon_388737 a rdfs:Class ; rdfs:label "SARS coronavirus GDH-BJH01" ; rdfs:subClassOf obo:NCBITaxon_694009 . a rdfs:Class ; rdfs:label "Delirium, Dementia, Amnestic, Cognitive Disorders [Disease/Finding]" ; rdfs:subClassOf . obo:OBI_0000659 a rdfs:Class ; rdfs:label "specimen collection process" ; rdfs:comment "A planned process with the objective of collecting a specimen." ; rdfs:subClassOf obo:OBI_0000011 . obo:PR_000005624 a rdfs:Class ; rdfs:label "UMP-CMP kinase" ; rdfs:comment "A protein that is a translation product of the human CMPK1 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:PR_000013151 a rdfs:Class ; rdfs:label "calcineurin subunit B type 2" ; rdfs:comment "A protein that is a translation product of the human PPP3R2 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:CHEBI_50334 a rdfs:Class ; rdfs:label "pyridinium ion" ; rdfs:subClassOf obo:CHEBI_25697 , obo:CHEBI_26421 . obo:CHEBI_82711 a rdfs:Class ; rdfs:label "aryl thiol" ; rdfs:comment "An aryl thiol is a thiol in which a sulfanyl group, SH, is attached to an aryl group." ; rdfs:subClassOf obo:CHEBI_29256 . obo:NCBITaxon_292360 a rdfs:Class ; rdfs:label "SARS Coronavirus CDC#200301157" ; rdfs:subClassOf obo:NCBITaxon_694009 . obo:HP_0031246 a rdfs:Class ; rdfs:label "Nonproductive cough" ; rdfs:comment "A cough that does not produce phlegm or mucus." ; rdfs:subClassOf obo:HP_0012735 . obo:NCBITaxon_389167 a rdfs:Class ; rdfs:label "Bat CoV 279/2005" ; rdfs:subClassOf obo:NCBITaxon_347536 . obo:OMRSE_00000007 a rdfs:Class ; rdfs:label "gender role"@en ; rdfs:comment "A human social role borne by a human being being realized in behaviour which is considered socially appropriate for individuals of a specific sex in the context of a specific culture."@en ; rdfs:subClassOf obo:BFO_0000023 . obo:PR_Q9NYY3 a rdfs:Class ; rdfs:label "serine/threonine-protein kinase PLK2 (human)" ; rdfs:comment "A serine/threonine-protein kinase PLK2 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000012871 , obo:PR_000029067 . a rdfs:Class ; rdfs:label "Physiologic States [Disease/Finding]" ; rdfs:subClassOf . a rdfs:Class ; rdfs:label "Lung Diseases [Disease/Finding]" ; rdfs:subClassOf . obo:NCBITaxon_236988 a rdfs:Class ; rdfs:label "Avian infectious bronchitis virus (strain D41)" ; rdfs:subClassOf obo:NCBITaxon_11120 . obo:PR_Q96L34 a rdfs:Class ; rdfs:label "MAP/microtubule affinity-regulating kinase 4 (human)" ; rdfs:comment "A MAP/microtubule affinity-regulating kinase 4 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000010189 , obo:PR_000029067 . obo:NCBITaxon_2591237 a rdfs:Class ; rdfs:label "Coronavirus BtRs-BetaCoV/YN2018D" ; rdfs:subClassOf obo:NCBITaxon_2720068 . obo:DOID_6088 a rdfs:Class ; rdfs:label "acute stress disorder" ; rdfs:comment "An anxiety disorder that has_symptom flashbacks, has_symptom bad dreams, has_symptom frightening thoughts, has_symptom avoidance or has_symptom hyperarousal of PTSD occurring within one month of a traumatic experience as Acute Stress Disorder or ASD." ; rdfs:subClassOf obo:DOID_2030 . a rdfs:Class ; rdfs:label "Scabies [Disease/Finding]" ; rdfs:subClassOf . obo:DOID_0060167 a rdfs:Class ; rdfs:label "seasonal affective disorder" ; rdfs:comment "A mental depression that involves presentation of depressive symptoms only during a specific season of the year." ; rdfs:subClassOf obo:DOID_1596 . obo:BFO_0000144 a rdfs:Class ; rdfs:label "process profile"@en ; rdfs:comment "b is a process_profile =Def. there is some process c such that b process_profile_of c (axiom label in BFO2 Reference: [093-002])"@en ; rdfs:subClassOf obo:BFO_0000015 . obo:PR_Q99500 a rdfs:Class ; rdfs:label "sphingosine 1-phosphate receptor 3 (human)" ; rdfs:comment "A sphingosine 1-phosphate receptor 3 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000001708 , obo:PR_000029067 . obo:CHEBI_37527 a rdfs:Class ; rdfs:label "acid" ; rdfs:comment "An acid is a molecular entity capable of donating a hydron (Bronsted acid) or capable of forming a covalent bond with an electron pair (Lewis acid)." ; rdfs:subClassOf obo:CHEBI_51086 . obo:GO_0010579 a rdfs:Class ; rdfs:subClassOf obo:CIDO_0000409 . obo:GO_0006954 a rdfs:Class ; rdfs:label "inflammatory response" ; rdfs:comment "The immediate defensive reaction (by vertebrate tissue) to infection or injury caused by chemical or physical agents. The process is characterized by local vasodilation, extravasation of plasma into intercellular spaces and accumulation of white blood cells and macrophages." ; rdfs:subClassOf obo:GO_0006952 . obo:NCBITaxon_264376 a rdfs:Class ; rdfs:label "SARS coronavirus TW-KC1" ; rdfs:subClassOf obo:NCBITaxon_264370 . obo:CHEBI_38532 a rdfs:Class ; rdfs:label "hydrazone" ; rdfs:comment "Compounds having the structure R2C=NNR2, formally derived from aldehydes or ketones by replacing =O by =NNH2 (or substituted analogues)." ; rdfs:subClassOf obo:CHEBI_35352 . obo:NCBITaxon_285948 a rdfs:Class ; rdfs:label "SARS coronavirus civet019" ; rdfs:subClassOf obo:NCBITaxon_694009 . obo:ENVO_01000060 a rdfs:Class ; rdfs:label "particulate matter"@en ; rdfs:comment "Particulate material is an environmental material which is composed of microscopic portions of solid or liquid material suspended in another environmental material." ; rdfs:subClassOf obo:ENVO_00010483 . obo:CIDO_0020316 a rdfs:Class ; rdfs:label "UNC Health SARS-CoV-2 real-time RT-PCR test" ; rdfs:seeAlso ; rdfs:subClassOf obo:CIDO_0000454 . obo:VO_0005412 a rdfs:Class ; rdfs:label "V-01-351/V-01D Bivalence Vaccine"@en ; rdfs:comment "A SARS-CoV-2 protein subunit vaccine manufactured by Livzon Pharmaceutical Group Inc." ; rdfs:subClassOf obo:VO_0005202 . obo:NCBITaxon_1415836 a rdfs:Class ; rdfs:label "Bat SARS-like coronavirus Rs4075" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:PR_000001137 a rdfs:Class ; rdfs:label "interleukin-1 receptor antagonist protein" ; rdfs:comment "A protein that is a translation product of the human IL1RN gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:CHEBI_11955 a rdfs:Class ; rdfs:label "4-amino-3-hydroxybutanoate" ; rdfs:comment "The conjugate base of gamma-amino-beta-hydroxybutyric acid arising from deprotonation of the carboxy group." ; rdfs:subClassOf obo:CHEBI_36059 , obo:CHEBI_71666 . obo:PR_000034089 a rdfs:Class ; rdfs:label "quinone-dependent D-lactate dehydrogenase" ; rdfs:comment "A protein that is a translation product of the Escherichia coli K-12 dld gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:PR_P06478 a rdfs:Class ; rdfs:subClassOf obo:PR_000000001 . obo:APOLLO_SV_00000549 a rdfs:Class ; rdfs:label "Susceptible-Infected-Resistant model"@en ; rdfs:comment "A compartmental disease transmission model that represents some infection in ecosystem in which there are compartments for susceptible individuals, infectious individuals, and recovered individuals, such that recovered individuals are immune to future infection."@en ; rdfs:subClassOf obo:APOLLO_SV_00000303 . obo:CHEBI_97212 a rdfs:Class ; rdfs:label "N-[(1R,3S,4aS,9aR)-1-(hydroxymethyl)-3-[2-oxo-2-[[(1R)-1-phenylethyl]amino]ethyl]-3,4,4a,9a-tetrahydro-1H-pyrano[3,4-b][1]benzofuran-6-yl]pyridine-3-carboxamide" ; rdfs:subClassOf obo:CHEBI_74927 . obo:PR_Q96S66 a rdfs:Class ; rdfs:label "chloride channel CLIC-like protein 1 (human)" ; rdfs:comment "A chloride channel CLIC-like protein 1 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000005526 , obo:PR_000029067 . obo:CIDO_0020076 a rdfs:Class ; rdfs:label "Clarifi COVID-19 Test Kit" ; rdfs:seeAlso ; rdfs:subClassOf obo:CIDO_0000454 . obo:NCBITaxon_1052158 a rdfs:Class ; rdfs:label "Feline coronavirus UU54" ; rdfs:subClassOf obo:NCBITaxon_12663 . a rdfs:Class ; rdfs:label "Serotonin Transporter Interactions [MoA]" ; rdfs:subClassOf . obo:PR_Q9H4B4 a rdfs:Class ; rdfs:label "serine/threonine-protein kinase PLK3 (human)" ; rdfs:comment "A serine/threonine-protein kinase PLK3 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000012872 , obo:PR_000029067 . obo:NCBITaxon_2591232 a rdfs:Class ; rdfs:label "Coronavirus BtRs-AlphaCoV/YN2018" ; rdfs:subClassOf obo:NCBITaxon_366617 . obo:CIDO_0001011 a rdfs:Class ; rdfs:label "BNT162b1 SARS-CoV-2 Vaccine" ; rdfs:subClassOf obo:CHEBI_23367 . obo:PR_O75311 a rdfs:Class ; rdfs:label "glycine receptor subunit alpha-3 (human)" ; rdfs:comment "A glycine receptor subunit alpha-3 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000008044 , obo:PR_000029067 . obo:PR_Q99988 a rdfs:Class ; rdfs:label "growth/differentiation factor 15 (human)" ; rdfs:comment "A growth/differentiation factor 15 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000007920 , obo:PR_000029067 . obo:PR_Q9NR96 a rdfs:Class ; rdfs:label "Toll-like receptor 9 (human)" ; rdfs:comment "A Toll-like receptor 9 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000001160 , obo:PR_000029067 . obo:CHEBI_35356 a rdfs:Class ; rdfs:label "dicarboximide" ; rdfs:comment "An imide in which the two acyl substituents on nitrogen are carboacyl groups." ; rdfs:subClassOf obo:CHEBI_24782 . obo:PR_000006958 a rdfs:Class ; rdfs:label "eukaryotic translation initiation factor 2-alpha kinase 1" ; rdfs:comment "A protein that is a translation product of the human EIF2AK1 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:CHEBI_19129 a rdfs:Class ; rdfs:label "11alpha-hydroxy steroid" ; rdfs:subClassOf obo:CHEBI_36841 . obo:CHEBI_48359 a rdfs:Class ; rdfs:label "protophilic solvent" ; rdfs:comment "Solvent that is capable of acting as a hydron (proton) acceptor." ; rdfs:subClassOf obo:CHEBI_39142 , obo:CHEBI_48354 . obo:DRON_00064769 a rdfs:Class ; rdfs:label "hydroxyprogesterone caproate (USP) 125 MG/ML Injectable Solution" ; rdfs:subClassOf obo:DRON_00024057 . obo:CHEBI_78767 a rdfs:Class ; rdfs:label "nelfinavir(1+)" ; rdfs:comment "An organic cation obtained by protonation of the tertiary amino group of nelfinavir." ; rdfs:subClassOf obo:CHEBI_25697 , obo:CHEBI_35274 . obo:PR_Q9BS26 a rdfs:Class ; rdfs:label "endoplasmic reticulum resident protein 44 (human)" ; rdfs:comment "An endoplasmic reticulum resident protein 44 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000016862 , obo:PR_000029067 . obo:NCBITaxon_1381363 a rdfs:Class ; rdfs:label "Bat coronavirus Rhhar/CII_KSA_002/Bisha/Saudi Arabia/2013" ; rdfs:subClassOf obo:NCBITaxon_366617 . obo:HP_0001742 a rdfs:Class ; rdfs:label "Nasal obstruction" ; rdfs:comment "Reduced ability to pass air through the nasal cavity often leading to mouth breathing." ; rdfs:subClassOf obo:HP_0000366 . obo:CHEBI_61379 a rdfs:Class ; rdfs:label "harmala alkaloid" ; rdfs:comment "Any member of a class of naturally occurring alkaloids based on a 1-methyl-9H-beta-carboline skeleton." ; rdfs:subClassOf obo:CHEBI_22315 , obo:CHEBI_60834 . obo:HP_0001919 a rdfs:Class ; rdfs:label "Acute kidney injury" ; rdfs:comment "Sudden loss of renal function, as manifested by decreased urine production, and a rise in serum creatinine or blood urea nitrogen concentration (azotemia)." ; rdfs:subClassOf obo:HP_0000083 . obo:PR_P35658 a rdfs:Class ; rdfs:label "nuclear pore complex protein Nup214 (human)" ; rdfs:comment "A nuclear pore complex protein Nup214 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000011515 , obo:PR_000029067 . obo:NCBITaxon_1679876 a rdfs:Class ; rdfs:label "Coronavirus Hare_CoV/La06_380/Lep_gra/ESP/2006" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:OBI_0001472 a rdfs:Class ; rdfs:label "specimen with known storage state"@en ; rdfs:comment "A specimen for which it is known whether it has been subjected to storage of a specified type." ; rdfs:subClassOf obo:OBI_0100051 . obo:CHEBI_26835 a rdfs:Class ; rdfs:label "sulfur molecular entity" ; rdfs:subClassOf obo:CHEBI_33304 . obo:CIDO_0020047 a rdfs:Class ; rdfs:label "binx health At-Home Nasal Swab COVID-19 Sample Collection Kit" ; rdfs:seeAlso ; rdfs:subClassOf obo:CIDO_0000455 . obo:CHEBI_51307 a rdfs:Class ; rdfs:label "diester" ; rdfs:comment "A diester is a compound containing two ester groups." ; rdfs:subClassOf obo:CHEBI_35701 . obo:CHEBI_37581 a rdfs:Class ; rdfs:label "gamma-lactone" ; rdfs:comment "A lactone having a five-membered lactone ring." ; rdfs:subClassOf obo:CHEBI_25000 . obo:VO_0005239 a rdfs:Class ; rdfs:label "FAKHRAVAC"@en ; rdfs:comment "A SARS-CoV-2 inactivated vaccine developed by Organization of Defensive Innovation and Research in Iran" ; rdfs:subClassOf obo:VO_0005201 . obo:GO_0009615 a rdfs:Class ; rdfs:label "response to virus" ; rdfs:comment "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a virus." ; rdfs:subClassOf obo:GO_0051707 . obo:NCBITaxon_258971 a rdfs:Class ; rdfs:label "SARS coronavirus TW8" ; rdfs:subClassOf obo:NCBITaxon_694009 . obo:NCBITaxon_2126133 a rdfs:Class ; rdfs:label "Water deer coronavirus" ; rdfs:subClassOf obo:NCBITaxon_11128 . obo:PR_000001923 a rdfs:Class ; rdfs:label "receptor-type tyrosine-protein kinase Tie" ; rdfs:comment "A protein with core architecture consisting of an extracellular region containing an Ig-like domain (Pfam:PF00047 or Pfam:PF10430), followed by 3 EGF-like domains (Pfam:PF07947 or Pfam:PF00053), another Ig-like domain, and 3 Fibronectin type III domains (Pfam:PF00041), and a cytoplasmic region containing the Protein tyrosine kinase domain (Pfam:PF07714)." ; rdfs:subClassOf obo:PR_000000001 . obo:CIDO_0000999 a rdfs:Class ; rdfs:label "SARS-CoV2 orf8 protein binding to human FKBP10" ; rdfs:comment "SARS-CoV2 orf8 protein binding to human FKBP10, as evidented by an affinity-purification mass spectrometry experiment" ; rdfs:subClassOf obo:CIDO_0000051 . obo:NCBITaxon_749422 a rdfs:Class ; rdfs:label "Black-headed gull coronavirus CIR-66187" ; rdfs:subClassOf obo:NCBITaxon_749416 . obo:NCBITaxon_2042582 a rdfs:Class ; rdfs:label "Coronavirus PREDICT CoV-58" ; rdfs:subClassOf obo:NCBITaxon_366617 . obo:OGG_0000000001 a rdfs:Class ; rdfs:label "genome"@en ; rdfs:comment "A genome is a material entity that represents the entirety of an organism's hereditary information. The genome includes both the genes and the non-coding sequences of the DNA and RNA." ; rdfs:subClassOf obo:BFO_0000040 . obo:NCBITaxon_1503281 a rdfs:Class ; rdfs:label "BtMf-AlphaCoV/GD2012-a" ; rdfs:subClassOf obo:NCBITaxon_366617 . obo:CIDO_0000829 a rdfs:Class ; rdfs:label "SARS-CoV2 nsp13 protein binding to human CEP250" ; rdfs:comment "SARS-CoV2 nsp13 protein binding to human CEP250, as evidented by an affinity-purification mass spectrometry experiment" ; rdfs:subClassOf obo:CIDO_0000058 . obo:CHEBI_28479 a rdfs:Class ; rdfs:label "D-tyrosine" ; rdfs:comment "An optically active form of tyrosine having D-configuration." ; rdfs:subClassOf obo:CHEBI_16733 , obo:CHEBI_18186 . obo:CHEBI_36338 a rdfs:Class ; rdfs:label "lepton" ; rdfs:comment "Lepton is a fermion that does not experience the strong force (strong interaction). The term is derived from the Greek lambdaepsilonpitauomicronsigma (small, thin)." ; rdfs:subClassOf obo:CHEBI_33233 , obo:CHEBI_36340 . obo:OPMI_0000523 a rdfs:Class ; rdfs:label "provenance of specimen record"@en ; rdfs:comment "A provenance of record that determines the source of the specimen record, as in an EHR system." ; rdfs:subClassOf obo:OPMI_0000512 . obo:NCBITaxon_1511626 a rdfs:Class ; rdfs:label "Coronavirus BtCoV/V16/HUN/2013" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:CHEBI_23116 a rdfs:Class ; rdfs:label "chlorine atom" ; rdfs:subClassOf obo:CHEBI_24473 . a rdfs:Class ; rdfs:label "Oxyurida Infections [Disease/Finding]" ; rdfs:subClassOf . obo:CIDO_0001004 a rdfs:Class ; rdfs:label "Bevacizumab" ; rdfs:subClassOf obo:CHEBI_23367 . a rdfs:Class ; rdfs:label "Male Urogenital Diseases [Disease/Finding]" ; rdfs:subClassOf . obo:PR_000014136 a rdfs:Class ; rdfs:label "E3 ubiquitin-protein ligase NRDP1" ; rdfs:comment "A protein that is a translation product of the human RNF41 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:CHEBI_35186 a rdfs:Class ; rdfs:label "terpene" ; rdfs:comment "A hydrocarbon of biological origin having carbon skeleton formally derived from isoprene [CH2=C(CH3)CH=CH2]." ; rdfs:subClassOf obo:CHEBI_24632 , obo:CHEBI_24913 . obo:PR_P39023 a rdfs:Class ; rdfs:label "60S ribosomal protein L3 (human)" ; rdfs:comment "A 60S ribosomal protein L3 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000014212 , obo:PR_000029067 . obo:CHEBI_189665 a rdfs:Class ; rdfs:label "EC 3.4.21.61 (kexin) inhibitor" ; rdfs:comment "An EC 3.4.21.* (serine endopeptidase) inhibitor that interferes with the action of kexin (EC 3.4.21.61)." ; rdfs:subClassOf obo:CHEBI_5924 . obo:VO_0005401 a rdfs:Class ; rdfs:label "RH109"@en ; rdfs:comment "A SARS-CoV-2 RNA vaccine by Wuhan Recogen Biotechnology Co., Ltd." ; rdfs:subClassOf obo:VO_0005198 . obo:PR_Q4V328 a rdfs:Class ; rdfs:label "GRIP1-associated protein 1 (human)" ; rdfs:comment "A GRIP1-associated protein 1 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000008256 , obo:PR_000029067 . obo:CHEBI_37604 a rdfs:Class ; rdfs:label "cis-octadec-9-ene" ; rdfs:subClassOf obo:CHEBI_37605 . obo:GO_0000187 a rdfs:Class ; rdfs:label "obsolete activation of MAPK activity" ; rdfs:comment "OBSOLETE. The initiation of the activity of the inactive enzyme MAP kinase (MAPK)." ; rdfs:subClassOf obo:CIDO_0000409 . obo:IDO_0000656 a rdfs:Class ; rdfs:label "horizontal pathogen transmission process" ; rdfs:comment "A pathogen transmission process in which a pathogen is transmitted from one host to another of the same Species, and the two hosts are not in a parent-child relationship." ; rdfs:subClassOf obo:TRANS_0000000 . a rdfs:Class ; rdfs:label "Pharmaceutical Preparations" ; rdfs:subClassOf obo:BFO_0000040 . obo:PR_P21709 a rdfs:Class ; rdfs:label "ephrin type-A receptor 1 (human)" ; rdfs:comment "An ephrin type-A receptor 1 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000007120 , obo:PR_000029067 . obo:CHEBI_25728 a rdfs:Class ; rdfs:label "osmolyte" ; rdfs:comment "A solute used by a cell under water stress to maintain cell volume." ; rdfs:subClassOf obo:CHEBI_24432 . obo:CHEBI_50103 a rdfs:Class ; rdfs:label "excitatory amino acid agonist" ; rdfs:comment "An agent that binds to and activates excitatory amino acid receptors." ; rdfs:subClassOf obo:CHEBI_35942 . obo:OBI_0002536 a rdfs:Class ; rdfs:label "cerebral cortex specimen" ; rdfs:comment "A specimen that is derived from cerebral cortex." ; rdfs:subClassOf obo:OBI_0001479 . obo:CIDO_0000172 a rdfs:Class ; rdfs:label "clinical drug product for COVID-19"@en ; rdfs:comment "A drug product that can be used to treat COVID-19 patient in clinic." ; rdfs:subClassOf obo:DRON_00000005 . obo:CHEBI_23019 a rdfs:Class ; rdfs:label "carbonyl group" ; rdfs:subClassOf obo:CHEBI_51422 . obo:CIDO_0020129 a rdfs:Class ; rdfs:label "EmpowerDX At-Home COVID-19 PCR Test Kit" ; rdfs:seeAlso ; rdfs:subClassOf obo:CIDO_0000455 . a rdfs:Class ; rdfs:label "Postoperative Complications [Disease/Finding]" ; rdfs:subClassOf . obo:VO_0000001 a rdfs:Class ; rdfs:label "vaccine" ; rdfs:comment "A vaccine is a processed material with the function that when administered, it prevents or ameliorates a disorder in a target organism by inducing or modifying adaptive immune responses specific to the antigens in the vaccine." ; rdfs:subClassOf obo:OBI_0000047 . obo:CIDO_0000749 a rdfs:Class ; rdfs:label "SARS-CoV2 M protein binding to human AKAP8L" ; rdfs:comment "SARS-CoV2 M protein binding to human AKAP8L, as evidented by an affinity-purification mass spectrometry experiment" ; rdfs:subClassOf obo:CIDO_0000055 . a rdfs:Class ; rdfs:label "Genetic Diseases, Inborn [Disease/Finding]" ; rdfs:subClassOf . obo:NCBITaxon_745731 a rdfs:Class ; rdfs:label "Coronavirus M.das/VM84/2007/NLD" ; rdfs:subClassOf obo:NCBITaxon_696098 . obo:NCBITaxon_1288692 a rdfs:Class ; rdfs:label "Bat coronavirus POA/2012/44" ; rdfs:subClassOf obo:NCBITaxon_366617 . obo:NCBITaxon_864611 a rdfs:Class ; rdfs:label "Bat coronavirus BR98-18/BGR/2008" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:PR_000010457 a rdfs:Class ; rdfs:label "mitogen-activated protein kinase kinase kinase 20" ; rdfs:comment "A protein that is a translation product of the human MAP3K20 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:NCBITaxon_2724758 a rdfs:Class ; rdfs:label "unclassified Luchacovirus" ; rdfs:subClassOf obo:NCBITaxon_2509492 . obo:CHEBI_51086 a rdfs:Class ; rdfs:label "chemical role" ; rdfs:comment "A role played by the molecular entity or part thereof within a chemical context." ; rdfs:subClassOf obo:CHEBI_50906 . obo:CHEBI_26078 a rdfs:Class ; rdfs:label "phosphoric acid" ; rdfs:comment "A phosphorus oxoacid that consists of one oxo and three hydroxy groups joined covalently to a central phosphorus atom." ; rdfs:subClassOf obo:CHEBI_59698 . obo:OBI_0000902 a rdfs:Class ; rdfs:label "post mortem specimen" ; rdfs:comment "a specimen that was taken from a dead organism" ; rdfs:subClassOf obo:OBI_0001506 . obo:CHEBI_169939 a rdfs:Class ; rdfs:label "camostat(1+)" ; rdfs:comment "A guanidinium ion resulting from the protonation of the guanidyl group of camostat. Major microspecies at pH 7.3." ; rdfs:subClassOf obo:CHEBI_60251 . a rdfs:Class ; rdfs:label "Neurotransmitter & Neuromuscular Transmitter Activity Alteration [PE]" ; rdfs:subClassOf . obo:PR_O75506 a rdfs:Class ; rdfs:label "heat shock factor-binding protein 1 (human)" ; rdfs:comment "A heat shock factor-binding protein 1 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000008768 , obo:PR_000029067 . obo:NCBITaxon_11130 a rdfs:Class ; rdfs:label "Bovine coronavirus strain L9" ; rdfs:subClassOf obo:NCBITaxon_11128 . obo:GO_0098662 a rdfs:Class ; rdfs:label "inorganic cation transmembrane transport" ; rdfs:comment "A process in which an inorganic cation is transported from one side of a membrane to the other by means of some agent such as a transporter or pore." ; rdfs:subClassOf obo:GO_0034220 , obo:GO_0098655 . obo:NCBITaxon_669513 a rdfs:Class ; rdfs:label "Bat coronavirus SLO1A0066/2008/SVN" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:NCBITaxon_1679887 a rdfs:Class ; rdfs:label "Coronavirus RCoV/D_RMU10_1226/Myo_gla/GER/2010" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:CIDO_0000464 a rdfs:Class ; rdfs:label "GNSLNHLTSQLRQNF" ; rdfs:comment "A coronavirus epitope that is part of some S protein from HCoV 229E composed of the following amino acids GNSLNHLTSQLRQNF" ; rdfs:subClassOf obo:CIDO_0000451 . obo:CHEBI_77736 a rdfs:Class ; rdfs:label "(S)-verapamil" ; rdfs:comment "A 2-(3,4-dimethoxyphenyl)-5-{[2-(3,4-dimethoxyphenyl)ethyl](methyl)amino}-2-(propan-2-yl)pentanenitrile that has S configuration." ; rdfs:subClassOf obo:CHEBI_77733 . obo:CHEBI_52396 a rdfs:Class ; rdfs:label "alpha-oxyketone" ; rdfs:comment "An oxyketone with the general formula R2C(=O) (R=/=H) where one or more of the R groups contains an oxy (-O-) group and the oxy and carbonyl groups are bonded to the same carbon atom." ; rdfs:subClassOf obo:CHEBI_52395 . obo:PR_000005418 a rdfs:Class ; rdfs:label "serine/threonine-protein kinase Chk2" ; rdfs:comment "A protein that is a translation product of the human CHEK2 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:NCBITaxon_1415847 a rdfs:Class ; rdfs:label "Bat SARS-like coronavirus Rs4097" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:CHEBI_35622 a rdfs:Class ; rdfs:label "thiazolidines" ; rdfs:subClassOf obo:CHEBI_25693 , obo:CHEBI_38101 , obo:CHEBI_38106 . obo:OPMI_0000548 a rdfs:Class ; rdfs:label "secondary referral diagnosis status"@en ; rdfs:subClassOf obo:OPMI_0000546 . obo:CIDO_0020171 a rdfs:Class ; rdfs:label "ID Now COVID-19" ; rdfs:seeAlso ; rdfs:subClassOf obo:CIDO_0000454 . obo:CHEBI_32449 a rdfs:Class ; rdfs:label "D-cysteinate(1-)" ; rdfs:comment "The D-enantiomer of cysteinate(1-)." ; rdfs:subClassOf obo:CHEBI_32456 . obo:CHEBI_420128 a rdfs:Class ; rdfs:label "5-chlorosalicylic acid" ; rdfs:comment "A monohydroxybenzoic acid that is 2-hydroxybenzoic acid (salicylic acid) in which the hydrogen at position 5 is replaced by chlorine." ; rdfs:subClassOf obo:CHEBI_23134 , obo:CHEBI_25389 , obo:CHEBI_83403 . obo:PR_000004753 a rdfs:Class ; rdfs:label "baculoviral IAP repeat-containing protein 5" ; rdfs:comment "A protein that is a translation product of the human BIRC5 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:CHEBI_49200 a rdfs:Class ; rdfs:label "EC 3.6.3.10 (H(+)/K(+)-exchanging ATPase) inhibitor" ; rdfs:comment "An EC 3.6.3.* (acid anhydride hydrolase catalysing transmembrane movement of substances) inhibitor that inhibits H(+)/K(+)-exchanging ATPase, EC 3.6.3.10. Such compounds are also known as proton pump inhibitors." ; rdfs:subClassOf obo:CHEBI_76895 . obo:PR_P94692 a rdfs:Class ; rdfs:subClassOf obo:PR_000000001 . obo:CIDO_0020323 a rdfs:Class ; rdfs:label "Viracor SARS-CoV-2 assay" ; rdfs:seeAlso ; rdfs:subClassOf obo:CIDO_0000454 . obo:CHEBI_35605 a rdfs:Class ; rdfs:label "carbon oxoacid" ; rdfs:subClassOf obo:CHEBI_24833 , obo:CHEBI_36963 . obo:PR_000010143 a rdfs:Class ; rdfs:label "mitogen-activated protein kinase kinase kinase kinase 1" ; rdfs:comment "A protein that is a translation product of the human MAP4K1 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:NCBITaxon_363228 a rdfs:Class ; rdfs:label "Spotted hyena coronavirus" ; rdfs:subClassOf obo:NCBITaxon_11153 . obo:NCBITaxon_37029 a rdfs:Class ; rdfs:label "Prionailurus bengalensis" ; rdfs:subClassOf obo:NCBITaxon_37028 . obo:PR_Q9Y6M9 a rdfs:Class ; rdfs:label "NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9 (human)" ; rdfs:comment "An NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000011093 , obo:PR_000029067 . obo:NCBITaxon_1415843 a rdfs:Class ; rdfs:label "Bat SARS-like coronavirus Rs4087-2" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:NCBITaxon_1699348 a rdfs:Class ; rdfs:label "Myotis Bat Alphacoronavirus strain YNXY_8C" ; rdfs:subClassOf obo:NCBITaxon_366617 . obo:DOID_1561 a rdfs:Class ; rdfs:label "cognitive disorder" ; rdfs:comment "A disease of mental health that affects cognitive functions including memory processing, perception and problem solving." ; rdfs:subClassOf obo:DOID_150 . a rdfs:Class ; rdfs:label "Cisapride [Chemical/Ingredient]" ; rdfs:subClassOf , . obo:NCBITaxon_694005 a rdfs:Class ; rdfs:label "Murine coronavirus" ; rdfs:subClassOf obo:NCBITaxon_2509481 . obo:NCBITaxon_1868637 a rdfs:Class ; rdfs:label "Bat coronavirus/4539/2013/Cynomops planirostris/Brazil" ; rdfs:subClassOf obo:NCBITaxon_366617 . obo:HP_0002829 a rdfs:Class ; rdfs:label "Arthralgia" ; rdfs:comment "Joint pain." ; rdfs:subClassOf obo:HP_0012531 . obo:CHEBI_25491 a rdfs:Class ; rdfs:label "nematicide" ; rdfs:comment "A substance used to destroy pests of the phylum Nematoda (roundworms)." ; rdfs:subClassOf obo:CHEBI_25944 . obo:CIDO_0020111 a rdfs:Class ; rdfs:label "Diagnovital SARS-CoV-2 Real-Time PCR Kit" ; rdfs:seeAlso ; rdfs:subClassOf obo:CIDO_0000454 . obo:NCBITaxon_308726 a rdfs:Class ; rdfs:label "Human coronavirus type 5" ; rdfs:subClassOf obo:NCBITaxon_696098 . obo:NCBITaxon_249086 a rdfs:Class ; rdfs:label "SARS coronavirus LC4" ; rdfs:subClassOf obo:NCBITaxon_694009 . obo:NCBITaxon_864614 a rdfs:Class ; rdfs:label "Bat coronavirus BR98-37/BGR/2008" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:CIDO_0000063 a rdfs:Class ; rdfs:label "Delta variant COVID-19 disease process"@en ; rdfs:comment "A COVID-19 disease process caused by the Delta SARS-CoV-2 variant." ; rdfs:subClassOf obo:CIDO_0000003 . obo:NCBITaxon_404135 a rdfs:Class ; rdfs:label "Bovine coronavirus isolate Alpaca" ; rdfs:subClassOf obo:NCBITaxon_11128 . obo:NCBITaxon_497947 a rdfs:Class ; rdfs:label "Bat coronavirus M.dau/Germany/D8.46/2007" ; rdfs:subClassOf obo:NCBITaxon_366617 . obo:PR_000006894 a rdfs:Class ; rdfs:label "ER degradation-enhancing alpha-mannosidase-like protein 3" ; rdfs:comment "A protein that is a translation product of the human EDEM3 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:PR_000007768 a rdfs:Class ; rdfs:label "gamma-aminobutyric acid receptor subunit alpha-3" ; rdfs:comment "A GABA(A) receptor protein that is a translation product of the human GABRA3 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000044664 . a rdfs:Class ; rdfs:label "Vasculitis [Disease/Finding]" ; rdfs:subClassOf . obo:CIDO_0000567 a rdfs:Class ; rdfs:label "VKNIPRYASAVAQAF" ; rdfs:comment "A coronavirus epitope that is part of some S protein from HCoV OC43 composed of the following amino acids VKNIPRYASAVAQAF" ; rdfs:subClassOf obo:CIDO_0000452 . obo:CIDO_0000789 a rdfs:Class ; rdfs:label "SARS-CoV2 N protein binding to human SNIP1" ; rdfs:comment "SARS-CoV2 N protein binding to human SNIP1, as evidented by an affinity-purification mass spectrometry experiment" ; rdfs:subClassOf obo:CIDO_0000056 . obo:CHEBI_59780 a rdfs:Class ; rdfs:label "cyclic hemiketal" ; rdfs:comment "A hemiacetal having the structure R2C(OH)OR (R =/= H), derived from a ketone by formal addition of an alcohol to the carbonyl group. The term 'cyclic hemiketals', once abandoned by IUPAC, has been reinstated as a subclass of hemiacetals." ; rdfs:subClassOf obo:CHEBI_38131 , obo:CHEBI_59772 . obo:GO_0090150 a rdfs:Class ; rdfs:label "establishment of protein localization to membrane" ; rdfs:comment "The directed movement of a protein to a specific location in a membrane." ; rdfs:subClassOf obo:GO_0045184 , obo:GO_0072657 . obo:CIDO_0020274 a rdfs:Class ; rdfs:label "SARS-CoV-2 Molecular Detection Assay" ; rdfs:seeAlso ; rdfs:subClassOf obo:CIDO_0000454 . obo:OBI_0001143 a rdfs:Class ; rdfs:label "labeled nucleic acid extract" ; rdfs:comment "a labeled specimen that is the output of a labeling process and has grain labeled nucleic acid for detection of the nucleic acid in future experiments." ; rdfs:subClassOf obo:OBI_0000924 . obo:NCBITaxon_1495253 a rdfs:Class ; rdfs:label "BtVs-BetaCoV/SC2013" ; rdfs:subClassOf obo:NCBITaxon_1335626 . obo:CIDO_0001103 a rdfs:Class ; rdfs:label "SARS-CoV2 orf8 protein binding to human TOR1A,"@en ; rdfs:comment "SARS-CoV2 orf8 protein binding to human TOR1A, as evidented by an affinity-purification mass spectrometry experiment" ; rdfs:subClassOf obo:CIDO_0000051 . obo:PR_Q8NBJ5 a rdfs:Class ; rdfs:label "procollagen galactosyltransferase 1 (human)" ; rdfs:comment "A procollagen galactosyltransferase 1 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000029067 , obo:PR_000029527 . obo:PR_000001342 a rdfs:Class ; rdfs:label "discoidin domain-containing receptor" ; rdfs:comment "A protein that has a core domain structure of an F5/8 type C (Pfam:PF00754) domain (or discoidin domain) followed by a Protein tyrosine kinase (Pfam:PF07714) domain. The discoidin domain receptors (DDRs) are distinguished from other members of the receptor tyrosine kinase family by a discoidin homology repeat in their extracellular domains that is also found in a variety of other transmembrane and secreted proteins." ; rdfs:subClassOf obo:PR_000000001 . a rdfs:Class ; rdfs:label "Porphyria Cutanea Tarda [Disease/Finding]" ; rdfs:subClassOf . obo:NCBITaxon_40674 a rdfs:Class ; rdfs:label "Mammalia" ; rdfs:subClassOf obo:NCBITaxon_32524 . obo:DRON_00020600 a rdfs:Class ; rdfs:label "Hydroxychloroquine Oral Tablet" ; rdfs:subClassOf obo:DRON_00000022 . obo:PR_000029094 a rdfs:Class ; rdfs:label "ankyrin repeat and protein kinase domain-containing protein 1" ; rdfs:comment "A protein that is a translation product of the human ANKK1 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . a rdfs:Class ; rdfs:label "Promethazine [Chemical/Ingredient]" ; rdfs:subClassOf , . obo:OBI_0002524 a rdfs:Class ; rdfs:label "urinary bladder specimen" ; rdfs:comment "A specimen that is derived from urinary bladder." ; rdfs:subClassOf obo:OBI_0001479 . obo:NCBITaxon_1679875 a rdfs:Class ; rdfs:label "Coronavirus Hare_CoV/La06_379/Lep_gra/ESP/2006" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:NCBITaxon_864595 a rdfs:Class ; rdfs:label "Bat coronavirus BM48-28/BGR/2008" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:CIDO_0020253 a rdfs:Class ; rdfs:label "Quest Diagnostics RC COVID-19+Flu RT-PCR" ; rdfs:seeAlso ; rdfs:subClassOf obo:CIDO_0000455 . obo:NCBITaxon_229992 a rdfs:Class ; rdfs:label "SARS coronavirus Frankfurt 1" ; rdfs:subClassOf obo:NCBITaxon_694009 . obo:VO_0005406 a rdfs:Class ; rdfs:label "Betuvax-CoV2"@en ; rdfs:comment "A SARS-CoV-2 protein subunit vaccine manufactured by Human Stem Cell Institute" ; rdfs:subClassOf obo:VO_0005202 . obo:UBERON_0007109 a rdfs:Class ; rdfs:label "meconium" ; rdfs:comment "A dark greenish mass that accumulates in the bowel during fetal life and is discharged shortly after birth." ; rdfs:subClassOf obo:UBERON_0001988 . obo:CHEBI_65191 a rdfs:Class ; rdfs:label "second generation antipsychotic" ; rdfs:comment "Antipsychotic drugs which can have different modes of action but which tend to be less likely than first generation antipsychotics to cause extrapyramidal motor control disabilities such as body rigidity or Parkinson's disease-type movements." ; rdfs:subClassOf obo:CHEBI_35476 . a rdfs:Class ; rdfs:label "Hydrocarbons [Chemical/Ingredient]" ; rdfs:subClassOf . obo:PR_Q86YT6 a rdfs:Class ; rdfs:label "E3 ubiquitin-protein ligase MIB1 (human)" ; rdfs:comment "An E3 ubiquitin-protein ligase MIB1 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000010396 , obo:PR_000029067 . obo:CHEBI_51447 a rdfs:Class ; rdfs:label "organic univalent group" ; rdfs:subClassOf obo:CHEBI_33247 . obo:NCBITaxon_903622 a rdfs:Class ; rdfs:label "Kenya bat coronavirus BtKY84" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:PR_000010159 a rdfs:Class ; rdfs:label "mitogen-activated protein kinase 7" ; rdfs:comment "A protein that is a translation product of the human MAPK7 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:CIDO_0001098 a rdfs:Class ; rdfs:label "SARS-CoV2 orf8 protein binding to human HS6ST2"@en ; rdfs:comment "SARS-CoV2 orf8 protein binding to human HS6ST2, as evidented by an affinity-purification mass spectrometry experiment" ; rdfs:subClassOf obo:CIDO_0000051 . obo:CHEBI_43474 a rdfs:Class ; rdfs:label "hydrogenphosphate" ; rdfs:comment "A phosphate ion that is the conjugate base of dihydrogenphosphate." ; rdfs:subClassOf obo:CHEBI_35780 , obo:CHEBI_79388 . a rdfs:Class ; rdfs:label "Neoplasms by Histologic Type [Disease/Finding]" ; rdfs:subClassOf . obo:CIDO_0020118 a rdfs:Class ; rdfs:label "Dimension EXL SARS-CoV-2 Total antibody assay (CV2T)" ; rdfs:seeAlso ; rdfs:subClassOf obo:CIDO_0000454 . obo:CIDO_0001158 a rdfs:Class ; rdfs:label "AA variant in SARS-CoV-2 S protein S2 UH region"@en ; rdfs:subClassOf obo:CIDO_0000595 . obo:CIDO_0000453 a rdfs:Class ; rdfs:label "COVID-19 diagnostic testing device" ; rdfs:comment "A device that is intended for use in the diagnosis for COVID-19 infection, or to measure the adaptive immune response to the SARS-CoV-2 virus."@en ; rdfs:subClassOf obo:OBI_0000968 . obo:CIDO_0001108 a rdfs:Class ; rdfs:label "SARS-CoV2 orf9b protein binding to human DPH5"@en ; rdfs:comment "SARS-CoV2 orf9b protein binding to human DPH5, as evidented by an affinity-purification mass spectrometry experiment" ; rdfs:subClassOf obo:CIDO_0000052 . obo:CHEBI_38500 a rdfs:Class ; rdfs:label "EC 1.9.3.1 (cytochrome c oxidase) inhibitor" ; rdfs:comment "An EC 1.9.3.* (oxidoreductase acting on donor heme group, oxygen as acceptor) inhibitor that interferes with the action of cytochrome c oxidase (EC 1.9.3.1)." ; rdfs:subClassOf obo:CHEBI_25355 , obo:CHEBI_76870 . obo:CIDO_0000190 a rdfs:Class ; rdfs:label "coronaviral RTC formation"@en ; rdfs:subClassOf obo:CIDO_0000204 . obo:CHEBI_33671 a rdfs:Class ; rdfs:label "heteropolycyclic compound" ; rdfs:comment "A polycyclic compound in which at least one of the rings contains at least one non-carbon atom." ; rdfs:subClassOf obo:CHEBI_33635 , obo:CHEBI_5686 . obo:CIDO_0001037 a rdfs:Class ; rdfs:label "Fostamatinib" ; rdfs:subClassOf obo:CHEBI_23367 . a rdfs:Class ; rdfs:label "Nematode Infections [Disease/Finding]" ; rdfs:subClassOf . obo:NCBITaxon_33734 a rdfs:Class ; rdfs:label "Feline infectious peritonitis virus (strain 79-1146)" ; rdfs:subClassOf obo:NCBITaxon_11135 . obo:NCBITaxon_711466 a rdfs:Class ; rdfs:label "Feline coronavirus UU23" ; rdfs:subClassOf obo:NCBITaxon_12663 . obo:CIDO_0000071 a rdfs:Class ; rdfs:label "chemical role modulating host immune response to viral infection"@en ; rdfs:comment "A role of a chemical effective in modulating host response to viral infection" ; rdfs:subClassOf obo:CIDO_0000069 . obo:NCBITaxon_389243 a rdfs:Class ; rdfs:label "Bat coronavirus (BtCoV/427/2005)" ; rdfs:subClassOf obo:NCBITaxon_389126 . obo:CHEBI_86969 a rdfs:Class ; rdfs:label "loperamide(1+)" ; rdfs:comment "An organic cation obtained by protonation of the tertiary amino function of loperamide." ; rdfs:subClassOf obo:CHEBI_25697 , obo:CHEBI_35274 . obo:OPMI_0000490 a rdfs:Class ; rdfs:label "visit start datetime"@en ; rdfs:comment "The date and time on which a visit starts. In the case of an inpatient visit this should be the date the patient was admitted to the hospital or institution. In all other cases this should be the date of the patient-provider interaction." ; rdfs:subClassOf obo:OPMI_0000285 . obo:PR_000007532 a rdfs:Class ; rdfs:label "peptidyl-prolyl cis-trans isomerase FKBP10" ; rdfs:comment "A protein that is a translation product of the human FKBP10 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:PR_000007360 a rdfs:Class ; rdfs:label "fibulin-5" ; rdfs:comment "A protein that is a translation product of the human FBLN5 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:PR_Q13310 a rdfs:Class ; rdfs:label "polyadenylate-binding protein 4 (human)" ; rdfs:comment "A polyadenylate-binding protein 4 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000012208 , obo:PR_000029067 . obo:CIDO_0020160 a rdfs:Class ; rdfs:label "Gravity Diagnostics SARS-CoV-2 RT-PCR Assay" ; rdfs:seeAlso ; rdfs:subClassOf obo:CIDO_0000454 . obo:CHEBI_31890 a rdfs:Class ; rdfs:label "nafamostat methanesulfonate" ; rdfs:subClassOf obo:CHEBI_24436 , obo:CHEBI_36054 , obo:CHEBI_38037 . obo:PR_Q9BSF4 a rdfs:Class ; rdfs:label "mitochondrial import inner membrane translocase subunit Tim29 (human)" ; rdfs:comment "A mitochondrial import inner membrane translocase subunit Tim29 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000029067 , obo:PR_000060044 . a rdfs:Class ; rdfs:label "Streptococcal Infections [Disease/Finding]" ; rdfs:subClassOf . obo:CIDO_0000225 a rdfs:Class ; rdfs:label "coronavirus RNA"@en ; rdfs:subClassOf obo:CHEBI_33697 . obo:CHEBI_48544 a rdfs:Class ; rdfs:label "methanesulfonates" ; rdfs:comment "Esters or salts of methanesulfonic acid." ; rdfs:subClassOf obo:CHEBI_33261 . obo:NCBITaxon_550972 a rdfs:Class ; rdfs:label "Bat coronavirus M.mac/Australia/CoV034/2008" ; rdfs:subClassOf obo:NCBITaxon_366617 . obo:CHEBI_25018 a rdfs:Class ; rdfs:label "L-leucine derivative" ; rdfs:comment "A proteinogenic amino acid derivative resulting from reaction of L-leucine at the amino group or the carboxy group, or from the replacement of any hydrogen of L-leucine by a heteroatom." ; rdfs:subClassOf obo:CHEBI_47003 , obo:CHEBI_83811 . obo:CHEBI_41977 a rdfs:Class ; rdfs:label "daunorubicin" ; rdfs:comment "A natural product found in Actinomadura roseola." ; rdfs:subClassOf obo:CHEBI_22507 , obo:CHEBI_25830 , obo:CHEBI_48120 , obo:CHEBI_51286 . obo:CIDO_0000831 a rdfs:Class ; rdfs:label "SARS-CoV2 nsp13 protein binding to human CEP43" ; rdfs:comment "SARS-CoV2 nsp13 protein binding to human CEP43, as evidented by an affinity-purification mass spectrometry experiment" ; rdfs:subClassOf obo:CIDO_0000058 . obo:NCBITaxon_10239 a rdfs:Class ; rdfs:label "Viruses" ; rdfs:subClassOf obo:BFO_0000040 , obo:OBI_0100026 . obo:PR_000015331 a rdfs:Class ; rdfs:label "SNF-related serine/threonine-protein kinase" ; rdfs:comment "A protein that is a translation product of the human SNRK gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:NCBITaxon_389136 a rdfs:Class ; rdfs:label "Bat coronavirus (BtCoV/A604/2005)" ; rdfs:subClassOf obo:NCBITaxon_389126 . obo:PR_Q6DT37 a rdfs:Class ; rdfs:label "serine/threonine-protein kinase MRCK gamma (human)" ; rdfs:comment "A serine/threonine-protein kinase MRCK gamma that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000005207 , obo:PR_000029067 . obo:HP_0030163 a rdfs:Class ; rdfs:label "Abnormal vascular physiology" ; rdfs:comment "Abnormality of vascular function." ; rdfs:subClassOf obo:HP_0002597 , obo:HP_0011025 . obo:VO_0005180 a rdfs:Class ; rdfs:label "nanoparticle vector"@en ; rdfs:comment "A vaccine component composed of a synthetic component that is solid and spherical structures ranging to around 100 nm in size and prepared from natural or synthetic polymers." ; rdfs:subClassOf obo:VO_0000179 . obo:GO_0070374 a rdfs:Class ; rdfs:label "positive regulation of ERK1 and ERK2 cascade" ; rdfs:comment "Any process that activates or increases the frequency, rate or extent of signal transduction mediated by the ERK1 and ERK2 cascade." ; rdfs:subClassOf obo:GO_0043408 , obo:GO_0043410 . obo:CIDO_0000381 a rdfs:Class ; rdfs:label "SARS-CoV-2 Theta variant"@en ; rdfs:subClassOf obo:CIDO_0000407 . obo:PR_Q9Y680 a rdfs:Class ; rdfs:label "peptidyl-prolyl cis-trans isomerase FKBP7 (human)" ; rdfs:comment "A peptidyl-prolyl cis-trans isomerase FKBP7 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000007543 , obo:PR_000029067 . obo:PR_000011526 a rdfs:Class ; rdfs:label "nuclear pore complex protein Nup98-Nup96" ; rdfs:comment "A protein that is a translation product of the human NUP98 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:PR_P20276 a rdfs:Class ; rdfs:subClassOf obo:PR_000000001 . obo:PR_000002030 a rdfs:Class ; rdfs:label "alpha-type platelet-derived growth factor receptor" ; rdfs:comment "A CSF-1/PDGF receptor-type tyrosine-protein kinase that is a translation product of the human PDGFRA gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000001810 . obo:CIDO_0000160 a rdfs:Class ; rdfs:label "MERS-CoV transmission"@en ; rdfs:subClassOf obo:CIDO_0000155 . a rdfs:Class ; rdfs:label "Filariasis [Disease/Finding]" ; rdfs:subClassOf . obo:IAO_0000027 a rdfs:Class ; rdfs:label "data item"@en ; rdfs:comment "An information content entity that is intended to be a truthful statement about something (modulo, e.g., measurement precision or other systematic errors) and is constructed/acquired by a method which reliably tends to produce (approximately) truthful statements."@en ; rdfs:subClassOf obo:IAO_0000030 . obo:OAE_0004540 a rdfs:Class ; rdfs:label "thrombosis with thrombocytopenia syndrome AE"@en ; rdfs:comment "An adverse event in any patient presenting with both acute venous or arterial thrombosis AND new onset thrombocytopenia after a medical intervention such as vaccination." ; rdfs:subClassOf obo:OAE_0000185 , obo:OAE_0001448 . a rdfs:Class ; rdfs:label "INTERFERON BETA-1B" ; rdfs:subClassOf . obo:PR_000050286 a rdfs:Class ; rdfs:label "proofreading exoribonuclease nsp14 (SARS-CoV-2)" ; rdfs:comment "An ORF1ab proteolytic cleavage product (SARS-CoV-2) that is the central portion produced by the enzymatic action of 3CL-PRO proteinase (nsp5) when it cleaves the precursor replicase polyprotein 1ab (SARS-CoV-2) between residues 5925-5926 and 6452-6453. UniProtKB:P0DTD1, 4393-5324." ; rdfs:subClassOf obo:PR_000050283 . obo:CIDO_0020151 a rdfs:Class ; rdfs:label "Genetrack SARS-CoV-2 Molecular Assay" ; rdfs:seeAlso ; rdfs:subClassOf obo:CIDO_0000454 . obo:NCBITaxon_931912 a rdfs:Class ; rdfs:label "Alphacoronavirus Eptesicus fuscus/Appalachian Ridge/P1-C264/IT/USA/2009" ; rdfs:subClassOf obo:NCBITaxon_366617 . obo:PR_000006782 a rdfs:Class ; rdfs:label "dual specificity tyrosine-phosphorylation-regulated kinase 1B" ; rdfs:comment "A protein that is a translation product of the human DYRK1B gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . a rdfs:Class ; rdfs:label "DIGITALIS" ; rdfs:subClassOf . obo:NCBITaxon_2042564 a rdfs:Class ; rdfs:label "Coronavirus PREDICT CoV-39" ; rdfs:subClassOf obo:NCBITaxon_366617 . obo:OGMS_0000061 a rdfs:Class ; rdfs:label "pathological bodily process" ; rdfs:comment "A bodily process that is clinically abnormal."@en ; rdfs:subClassOf obo:OGMS_0000060 . obo:PR_000012872 a rdfs:Class ; rdfs:label "serine/threonine-protein kinase PLK3" ; rdfs:comment "A protein that is a translation product of the human PLK3 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:NCBITaxon_31625 a rdfs:Class ; rdfs:label "Avian infectious bronchitis virus (strain PORTUGAL/322/82)" ; rdfs:subClassOf obo:NCBITaxon_11120 . obo:GO_0051339 a rdfs:Class ; rdfs:label "regulation of lyase activity" ; rdfs:comment "Any process that modulates the frequency, rate or extent of lyase activity, the catalysis of the cleavage of C-C, C-O, C-N and other bonds by other means than by hydrolysis or oxidation, or conversely adding a group to a double bond. They differ from other enzymes in that two substrates are involved in one reaction direction, but only one in the other direction. When acting on the single substrate, a molecule is eliminated and this generates either a new double bond or a new ring." ; rdfs:subClassOf obo:GO_0050790 . a rdfs:Class ; rdfs:label "Increased Cytokine Activity [PE]" ; rdfs:subClassOf . a rdfs:Class ; rdfs:label "Coma [Disease/Finding]" ; rdfs:subClassOf . obo:CIDO_0000469 a rdfs:Class ; rdfs:label "LLCRVTLGDFTIMSG" ; rdfs:comment "A coronavirus epitope that is part of some S protein from HCoV HKU1 composed of the following amino acids LLCRVTLGDFTIMSG" ; rdfs:subClassOf obo:CIDO_0000450 . obo:CIDO_0000854 a rdfs:Class ; rdfs:label "SARS-CoV2 nsp13 protein binding to human PRKAR2A" ; rdfs:comment "SARS-CoV2 nsp13 protein binding to human PRKAR2A, as evidented by an affinity-purification mass spectrometry experiment" ; rdfs:subClassOf obo:CIDO_0000058 . obo:GO_0010468 a rdfs:Class ; rdfs:label "regulation of gene expression" ; rdfs:comment "Any process that modulates the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product (protein or RNA)." ; rdfs:subClassOf obo:GO_0060255 . obo:CHEBI_64047 a rdfs:Class ; rdfs:label "food additive" ; rdfs:comment "Any substance which is added to food to preserve or enhance its flavour and/or appearance." ; rdfs:subClassOf obo:CHEBI_33232 , obo:CHEBI_78295 . obo:VO_0005189 a rdfs:Class ; rdfs:label "hAd5-COVID-19"@en ; rdfs:comment "A SARS-CoV-2 human adenovirus serotype 5 (hAd5) vector vaccine with E1/E2b/E3 deletions expressing SARS-CoV-2 viral antigen spike fusion protein and nucleocapsid with an enhanced T-cell stimulation domain." ; rdfs:subClassOf obo:VO_0005200 . obo:GO_1902187 a rdfs:Class . obo:CIDO_0000690 a rdfs:Class ; rdfs:label "R158G in SARS-CoV-2 S protein" ; rdfs:comment "An AA mutation or AA variant that has mutated an amino acid at position 158 into a glycine" ; rdfs:subClassOf obo:CIDO_0000594 . obo:NCBITaxon_1379867 a rdfs:Class ; rdfs:label "Bat coronavirus P.davyi49/Mexico/2012" ; rdfs:subClassOf obo:NCBITaxon_696098 . a rdfs:Class ; rdfs:label "Decreased Histamine Activity [PE]" ; rdfs:subClassOf , . obo:CHEBI_32443 a rdfs:Class ; rdfs:label "L-cysteinate(2-)" ; rdfs:comment "The L-enantiomer of cysteinate(2-)." ; rdfs:subClassOf obo:CHEBI_32457 . obo:PR_Q9NXH9 a rdfs:Class ; rdfs:label "tRNA (guanine(26)-N(2))-dimethyltransferase (human)" ; rdfs:comment "An N(2),N(2)-dimethylguanosine tRNA methyltransferase that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000016677 , obo:PR_000029067 . obo:CIDO_0001215 a rdfs:Class ; rdfs:label "Multiple Real-Time PCR Kit for Detection of 2019-nCoV. (Beijing Applied Biological Technologies Co., Ltd.)" ; rdfs:comment "Poduct storage conditions and expiration date: Store in the dark at -20±5℃, valid for 12 months." ; rdfs:subClassOf obo:CIDO_0000021 . obo:CHEBI_64909 a rdfs:Class ; rdfs:label "poison" ; rdfs:comment "Any substance that causes disturbance to organisms by chemical reaction or other activity on the molecular scale, when a sufficient quantity is absorbed by the organism." ; rdfs:subClassOf obo:CHEBI_24432 . obo:PR_P53671 a rdfs:Class ; rdfs:label "LIM domain kinase 2 (human)" ; rdfs:comment "A LIM domain kinase 2 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000009817 , obo:PR_000029067 . obo:CHEBI_22507 a rdfs:Class ; rdfs:label "aminoglycoside antibiotic" ; rdfs:subClassOf obo:CHEBI_23007 , obo:CHEBI_47779 . obo:DRON_00000030 a rdfs:Class ; rdfs:label "role of scattered molecular aggregate"@en ; rdfs:comment "a role borne by a scattered molecular aggregate and realized by its grains participating in one or more processes"@en ; rdfs:subClassOf obo:BFO_0000023 . obo:BFO_0000024 a rdfs:Class ; rdfs:label "fiat object"@en ; rdfs:subClassOf obo:BFO_0000040 . obo:OGG_20000011118 a rdfs:Class ; rdfs:label "gene of coronavirus" ; rdfs:comment "A gene that is part of a genome of coronavirus." ; rdfs:subClassOf obo:OGG_0000000002 , obo:OGG_20010239 . obo:PR_000004875 a rdfs:Class ; rdfs:label "complement C1q subcomponent subunit A" ; rdfs:comment "A protein that is a translation product of the human C1QA gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . a rdfs:Class ; rdfs:label "Carcinoma [Disease/Finding]" ; rdfs:subClassOf . obo:UBERON_0004648 a rdfs:Class ; rdfs:label "esophagus muscularis mucosa" ; rdfs:comment "A muscularis mucosa that is part of a esophagus." ; rdfs:subClassOf obo:UBERON_0000479 . obo:DRON_00012681 a rdfs:Class ; rdfs:label "Teicoplanin" ; rdfs:subClassOf obo:OBI_0000047 . obo:CIDO_0000327 a rdfs:Class ; rdfs:label "AYSNNSIAIPTNFTI"@en ; rdfs:subClassOf obo:CIDO_0000314 . a rdfs:Class ; rdfs:label "Azoles [Chemical/Ingredient]" ; rdfs:subClassOf . obo:PR_O95684 a rdfs:Class ; rdfs:label "centrosomal protein 43 (human)" ; rdfs:comment "A centrosomal protein 43 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000007504 , obo:PR_000029067 . obo:NCBITaxon_1487704 a rdfs:Class ; rdfs:label "Rhinolophus ferrumequinum coronavirus" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:NCBITaxon_389150 a rdfs:Class ; rdfs:label "Bat coronavirus (BtCoV/A894/2005)" ; rdfs:subClassOf obo:NCBITaxon_389126 . obo:NCBITaxon_1679919 a rdfs:Class ; rdfs:label "Coronavirus RCoV/RMU10_3212/Myo_gla/GER/2010" ; rdfs:subClassOf obo:NCBITaxon_2664420 . a rdfs:Class ; rdfs:label "Kidney Failure [Disease/Finding]" ; rdfs:subClassOf . obo:CIDO_0000250 a rdfs:Class ; rdfs:label "cleavage of angiotensin into angiotension II by ACE"@en ; rdfs:comment "ACE is a central component of the renin–angiotensin system (RAS), which controls blood pressure by regulating the volume of fluids in the body. ACE indirectly increases blood pressure by causing blood vessels to constrict. ACE inhibitors are widely used as pharmaceutical drugs for treatment of cardiovascular diseases." ; rdfs:subClassOf obo:GO_0016485 . obo:PR_Q13882 a rdfs:Class ; rdfs:label "protein-tyrosine kinase 6 (human)" ; rdfs:comment "A protein-tyrosine kinase 6 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000013434 , obo:PR_000029067 . obo:NCBITaxon_384336 a rdfs:Class ; rdfs:label "Human coronavirus NO/1055/04" ; rdfs:subClassOf obo:NCBITaxon_384335 . obo:CHEBI_36360 a rdfs:Class ; rdfs:label "phosphorus oxoacids and derivatives" ; rdfs:subClassOf obo:CHEBI_26082 . obo:NCBITaxon_766792 a rdfs:Class ; rdfs:label "Mink coronavirus strain WD1133" ; rdfs:subClassOf obo:NCBITaxon_2727857 . obo:CHEBI_52837 a rdfs:Class ; rdfs:label "quinolinium ion" ; rdfs:subClassOf obo:CHEBI_25697 . obo:CIDO_0000922 a rdfs:Class ; rdfs:label "SARS-CoV2 nsp7 protein binding to human TOR1AIP1" ; rdfs:comment "SARS-CoV2 nsp7 protein binding to human TOR1AIP1, as evidented by an affinity-purification mass spectrometry experiment" ; rdfs:subClassOf obo:CIDO_0000049 . obo:CIDO_0020218 a rdfs:Class ; rdfs:label "NxTAGCoV Extended Panel Assay" ; rdfs:seeAlso ; rdfs:subClassOf obo:CIDO_0000454 . obo:PR_Q96HW7 a rdfs:Class ; rdfs:label "integrator complex subunit 4 (human)" ; rdfs:comment "An integrator complex subunit 4 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000009071 , obo:PR_000029067 . obo:CHEBI_76861 a rdfs:Class ; rdfs:label "EC 1.4.3.* (oxidoreductase acting on donor CH-NH2 group, oxygen as acceptor) inhibitor" ; rdfs:comment "An EC 1.4.* (oxidoreductase acting on donor CH-NH2 group) inhibitor that interferes with the action of any such enzyme using oxygen as acceptor (EC 1.4.3.*)." ; rdfs:subClassOf obo:CHEBI_76730 . obo:NCBITaxon_422133 a rdfs:Class ; rdfs:label "Sambar deer coronavirus US/OH-WD388-TC/1994" ; rdfs:subClassOf obo:NCBITaxon_11128 . obo:CHEBI_60783 a rdfs:Class ; rdfs:label "nucleoside analogue" ; rdfs:comment "An analogue of a nucleoside, being an N-glycosyl compound in which the nitrogen-containing moiety is a modified nucleotide base. They are commonly used as antiviral products to prevent viral replication in infected cells." ; rdfs:subClassOf obo:CHEBI_21731 . a rdfs:Class ; rdfs:label "CETYLPYRIDINIUM CHLORIDE" ; rdfs:subClassOf . obo:CIDO_0001026 a rdfs:Class ; rdfs:label "CD24Fc" ; rdfs:subClassOf obo:CHEBI_23367 . obo:CHEBI_176842 a rdfs:Class ; rdfs:label "vitamin B9" ; rdfs:comment "Any B-vitamin that exhibits biological activity against vitamin B9 deficiency. Vitamin B9 refers to the many forms of folic acid and its derivatives, including tetrahydrofolic acid (the active form), methyltetrahydrofolate (the primary form found in blood), methenyltetrahydrofolate, folinic acid amongst others. They are present in abundance in green leafy vegetables, citrus fruits, and animal products. Lack of vitamin B9 leads to anemia, a condition in which the body cannot produce sufficient number of red blood cells. Symptoms of vitamin B9 deficiency include fatigue, muscle weakness, and pale skin." ; rdfs:subClassOf obo:CHEBI_75769 . obo:NCBITaxon_333387 a rdfs:Class ; rdfs:label "Bat SARS coronavirus HKU3-1" ; rdfs:subClassOf obo:NCBITaxon_442736 . obo:GO_2000145 a rdfs:Class ; rdfs:label "regulation of cell motility" ; rdfs:comment "Any process that modulates the frequency, rate or extent of cell motility." ; rdfs:subClassOf obo:GO_0040012 , obo:GO_0051270 . obo:CIDO_0001119 a rdfs:Class ; rdfs:label "SARS-CoV2 orf8 protein binding to human GDF15"@en ; rdfs:comment "SARS-CoV2 orf8 protein binding to human GDF15, as evidented by an affinity-purification mass spectrometry experiment" ; rdfs:subClassOf obo:CIDO_0000051 . obo:PR_P05556 a rdfs:Class ; rdfs:label "integrin beta-1 (human)" ; rdfs:comment "An integrin beta-1 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000002040 , obo:PR_000029067 . obo:CIDO_0000992 a rdfs:Class ; rdfs:label "SARS-CoV2 orf8 protein binding to human DNMT1" ; rdfs:comment "SARS-CoV2 orf8 protein binding to human DNMT1, as evidented by an affinity-purification mass spectrometry experiment" ; rdfs:subClassOf obo:CIDO_0000051 . obo:NCBITaxon_389156 a rdfs:Class ; rdfs:label "Bat coronavirus (BtCoV/A906/2005)" ; rdfs:subClassOf obo:NCBITaxon_389126 . obo:CHEBI_87113 a rdfs:Class ; rdfs:label "antibiotic antifungal drug" ; rdfs:comment "Any antibiotic antifungal agent used to treat fungal infections in humans or animals." ; rdfs:subClassOf obo:CHEBI_86478 . obo:CHEBI_34994 a rdfs:Class ; rdfs:label "teicoplanin A2" ; rdfs:comment "Any of the glycopeptides whose structure consists of teicoplanin A3-1 in which the hydroxy group of the di(aryloxy)-substituted phenol moiety has been converted to the corresponding 2-acylamino-2-deoxy-beta-D-glucoside. Members of the class differ only in the nature of the acyl group." ; rdfs:subClassOf obo:CHEBI_22160 , obo:CHEBI_24396 , obo:CHEBI_26195 , obo:CHEBI_35618 , obo:CHEBI_51026 , obo:CHEBI_83403 . obo:CIDO_0001143 a rdfs:Class ; rdfs:label "SARS-CoV-2 BA.2.12.1 virus"@en ; rdfs:comment "A SARS-CoV-2 Omicron variant virus that has a majority of the following mutations:" ; rdfs:subClassOf obo:CIDO_0000406 , obo:CIDO_0000590 . obo:CIDO_0020204 a rdfs:Class ; rdfs:label "MidaSpot COVID-19 Antibody Combo Detection Kit" ; rdfs:seeAlso ; rdfs:subClassOf obo:CIDO_0000454 . obo:NCBITaxon_864604 a rdfs:Class ; rdfs:label "Bat coronavirus BM98-07/BGR/2008" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:NCBITaxon_2 a rdfs:Class ; rdfs:label "Bacteria" ; rdfs:subClassOf obo:OBI_0100026 . obo:PR_000009686 a rdfs:Class ; rdfs:label "serine/threonine-protein kinase LATS1" ; rdfs:comment "A protein that is a translation product of the human LATS1 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:VO_0000340 a rdfs:Class ; rdfs:label "intramuscular route" ; rdfs:comment "a route of administration that inject the material(such as vaccines, allergens) directly into a muscle." ; rdfs:subClassOf obo:VO_0000574 . obo:UBERON_0001255 a rdfs:Class ; rdfs:label "urinary bladder" ; rdfs:comment "distensible musculomembranous organ situated in the anterior part of the pelvic cavity in which urine collects before excretion[MP]." ; rdfs:subClassOf obo:UBERON_0000465 . obo:PR_Q9NWZ3 a rdfs:Class ; rdfs:label "interleukin-1 receptor-associated kinase 4 (human)" ; rdfs:comment "An interleukin-1 receptor-associated kinase 4 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000001780 , obo:PR_000029067 . obo:PR_000029669 a rdfs:Class ; rdfs:label "PDZ domain-containing protein 11" ; rdfs:comment "A protein that is a translation product of the human PDZD11 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:NCBITaxon_461307 a rdfs:Class ; rdfs:label "Rocky Mountain Bat Coronavirus 48" ; rdfs:subClassOf obo:NCBITaxon_366617 . obo:CHEBI_37606 a rdfs:Class ; rdfs:label "octadecene" ; rdfs:comment "An alkene that is octadecane containing one double bond at unspecified position." ; rdfs:subClassOf obo:CHEBI_32878 . obo:CHEBI_55322 a rdfs:Class ; rdfs:label "mu-opioid receptor agonist" ; rdfs:comment "A compound that exhibits agonist activity at the mu-opioid receptor." ; rdfs:subClassOf obo:CHEBI_60599 , obo:CHEBI_60606 . obo:NCBITaxon_258964 a rdfs:Class ; rdfs:label "SARS coronavirus TW11" ; rdfs:subClassOf obo:NCBITaxon_694009 . obo:OBI_0000409 a rdfs:Class ; rdfs:label "nucleic acid template role"@en ; rdfs:comment "a reference substance role which inheres in nucleic acid material entity and is realized in the process of using the nucleic acid bearing the template role as a reference during synthesis of a reverse copy." ; rdfs:subClassOf obo:OBI_0000025 . obo:VO_0005109 a rdfs:Class ; rdfs:label "SARS rMA15-ΔE vaccine" ; rdfs:comment "A SARS recombinant vector vaccine that is made from recombinant MA15 virulent mouse-adapted SARS-CoV (MA15) background of E-deleted vaccine candidate (rMA15-ΔE)" ; rdfs:subClassOf obo:VO_0012183 . obo:CHEBI_53443 a rdfs:Class ; rdfs:label "salicylamides" ; rdfs:subClassOf obo:CHEBI_22702 . obo:HP_0031672 a rdfs:Class ; rdfs:label "Reverse typical atrial flutter" ; rdfs:comment "A type of atrial flutter associated with rounded or bimodal positive deflections in inferior leads II, III and aVF, and a very characteristic bimodal negative wave in the shape of a W is seen in lead V1." ; rdfs:subClassOf obo:HP_0004749 . obo:GO_0034470 a rdfs:Class ; rdfs:label "ncRNA processing" ; rdfs:comment "Any process that results in the conversion of one or more primary non-coding RNA (ncRNA) transcripts into one or more mature ncRNA molecules." ; rdfs:subClassOf obo:GO_0016070 , obo:GO_0034660 . a rdfs:Class ; rdfs:label "Musculoskeletal Diseases [Disease/Finding]" ; rdfs:subClassOf . obo:NCBITaxon_2732506 a rdfs:Class ; rdfs:label "Pisoniviricetes" ; rdfs:subClassOf obo:NCBITaxon_2732396 , obo:NCBITaxon_2732408 . obo:CHEBI_65023 a rdfs:Class ; rdfs:label "anti-asthmatic agent" ; rdfs:comment "Any compound that has anti-asthmatic effects." ; rdfs:subClassOf obo:CHEBI_33232 . obo:OGG_3043740570 a rdfs:Class ; rdfs:label "E gene of severe acute respiratory syndrome coronavirus 2" ; rdfs:comment "NCBI Gene ID:43740570" ; rdfs:subClassOf obo:OGG_2002697049 . obo:CHEBI_33676 a rdfs:Class ; rdfs:label "d-block molecular entity" ; rdfs:comment "A d-block molecular entity is a molecular entity containing one or more atoms of a d-block element." ; rdfs:subClassOf obo:CHEBI_33497 . a rdfs:Class ; rdfs:label "Mononegavirales Infections [Disease/Finding]" ; rdfs:subClassOf . obo:PR_Q8IU85 a rdfs:Class ; rdfs:label "calcium/calmodulin-dependent protein kinase type 1D (human)" ; rdfs:comment "A calcium/calmodulin-dependent protein kinase type 1D that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000004989 , obo:PR_000029067 . obo:PR_000001781 a rdfs:Class ; rdfs:label "interleukin-1 receptor-associated kinase IRAK1/3" ; rdfs:comment "A protein with core domain architecture consisting of an N-terminal Death domain (Pfam:PF00531) followed by a Protein kinase domain (Pfam:PF00069). This class is closely related to IRAK-4 (PR:000001780), but it contains an extra C-terminal region of about 200 residues." ; rdfs:subClassOf obo:PR_000000001 . obo:CIDO_0020162 a rdfs:Class ; rdfs:label "Guardant-19" ; rdfs:seeAlso ; rdfs:subClassOf obo:CIDO_0000454 . obo:CIDO_0000227 a rdfs:Class ; rdfs:label "ligand role"@en ; rdfs:subClassOf obo:BFO_0000023 . a rdfs:Class ; rdfs:label "Fluphenazine [Chemical/Ingredient]" ; rdfs:subClassOf . obo:OBI_1110120 a rdfs:Class ; rdfs:label "assay antigen role"@en ; rdfs:comment "Any molecule recognized by the adaptive immune receptors? Recognized means bound with a certain affinity? From GO ag binding:Interacting selectively with an antigen, any substance which is capable of inducing a specific immune response and of reacting with the products of that response, the specific antibody or specifically sensitized T-lymphocytes, or both. Binding may counteract the biological activity of the antigen. see OBI_1110120 below"@en ; rdfs:subClassOf obo:BFO_0000023 . obo:CHEBI_59826 a rdfs:Class ; rdfs:label "progestin" ; rdfs:comment "A synthetic progestogen." ; rdfs:subClassOf obo:CHEBI_50745 . obo:HP_0000924 a rdfs:Class ; rdfs:label "Abnormality of the skeletal system" ; rdfs:comment "An abnormality of the skeletal system." ; rdfs:subClassOf obo:HP_0033127 . obo:PR_Q7L8L6 a rdfs:Class ; rdfs:label "FAST kinase domain-containing protein 5, mitochondrial (human)" ; rdfs:comment "A FAST kinase domain-containing protein 5, mitochondrial that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000029067 , obo:PR_000029108 . obo:NCBITaxon_2042593 a rdfs:Class ; rdfs:label "Coronavirus PREDICT CoV-70" ; rdfs:subClassOf obo:NCBITaxon_366617 . obo:GO_0010646 a rdfs:Class ; rdfs:label "regulation of cell communication" ; rdfs:comment "Any process that modulates the frequency, rate or extent of cell communication. Cell communication is the process that mediates interactions between a cell and its surroundings. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment." ; rdfs:subClassOf obo:GO_0050794 . obo:OBI_0000876 a rdfs:Class ; rdfs:label "cytoplasmic RNA extract" ; rdfs:comment "A RNA extract that is the output of a RNA extraction process in which RNA molecules found in the cytoplasm are extracted." ; rdfs:subClassOf obo:OBI_0000880 . obo:OGG_2000009606 a rdfs:Class ; rdfs:label "gene of Homo sapiens" ; rdfs:comment "A gene of an organism of Homo sapiens" ; rdfs:subClassOf obo:OGG_2000002759 . obo:NCBITaxon_1261614 a rdfs:Class ; rdfs:label "Rhinolophus bat coronavirus/Rwanda/441/2008" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:NCBITaxon_903579 a rdfs:Class ; rdfs:label "Kenya bat coronavirus BtKY111" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:DRON_00058882 a rdfs:Class ; rdfs:label "Clomipramine Hydrochloride 75 MG Extended Release Tablet" ; rdfs:subClassOf obo:DRON_00021389 . obo:NCBITaxon_1076424 a rdfs:Class ; rdfs:label "Alphacoronavirus P.kuh/Iprima/Spain/2007" ; rdfs:subClassOf obo:NCBITaxon_366617 . obo:PR_000006312 a rdfs:Class ; rdfs:label "serine/threonine-protein kinase DCLK3" ; rdfs:comment "A doublecortin-like kinase that is a translation product of the human DCLK3 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000050059 . obo:CHEBI_146176 a rdfs:Class ; rdfs:label "levomethorphan" ; rdfs:comment "A 6-methoxy-11-methyl-1,3,4,9,10,10a-hexahydro-2H-10,4a-(epiminoethano)phenanthrene in which the stereocenters at positions 4a, 10 and 10a have R-configuration. It is a prodrug of levorphanol and a strong narcotic analgesic, and listed as a schedule II controlled substance." ; rdfs:subClassOf obo:CHEBI_146178 . obo:VO_0005228 a rdfs:Class ; rdfs:label "ChAdV68-S"@en ; rdfs:comment "A SARS-CoV-2 Chimpanzee Adenovirus serotype 6 vector vaccine manufactured by Gritstone Oncology and the National Institute of Allergy and Infectious Diseases" ; rdfs:subClassOf obo:VO_0005200 . obo:DRON_00024510 a rdfs:Class ; rdfs:label "Sirolimus Oral Solution" ; rdfs:subClassOf obo:DRON_00000020 . obo:CIDO_0020226 a rdfs:Class ; rdfs:label "Orig3n 2019 Novel Coronavirus (COVID-19) Test" ; rdfs:seeAlso ; rdfs:subClassOf obo:CIDO_0000454 . a rdfs:Class ; rdfs:label "TELAVANCIN" ; rdfs:subClassOf . obo:NCBITaxon_502104 a rdfs:Class ; rdfs:label "Murine coronavirus MHV-3" ; rdfs:subClassOf obo:NCBITaxon_11138 . obo:NCBITaxon_497930 a rdfs:Class ; rdfs:label "Bat coronavirus M.das/Germany/D3.3/2007" ; rdfs:subClassOf obo:NCBITaxon_366617 . obo:GAZ_00000448 a rdfs:Class ; rdfs:label "geographic location" ; rdfs:comment "A reference to a place on the Earth, by its name or by its geographical location." ; rdfs:subClassOf obo:BFO_0000029 . obo:CIDO_0001204 a rdfs:Class ; rdfs:label "Multiple Real-Time PCR Kit for Detection of 2019-nCoV. (Beijing Kinghawk Pharmaceutical Co.,Ltd.)" ; rdfs:comment "Manufacturor: Beijing Kinghawk Pharmaceutical Co.,Ltd. 北京金豪制药股份有限公司" ; rdfs:subClassOf obo:CIDO_0000021 . obo:VO_0005201 a rdfs:Class ; rdfs:label "COVID-19 inactivated vaccine"@en ; rdfs:subClassOf obo:VO_0004908 . obo:CHEBI_48360 a rdfs:Class ; rdfs:label "amphiprotic solvent" ; rdfs:comment "Self-ionizing solvent possessing both characteristics of Bronsted acids and bases." ; rdfs:subClassOf obo:CHEBI_48356 , obo:CHEBI_48359 . obo:PR_Q96IZ5 a rdfs:Class ; rdfs:label "RNA-binding protein 41 (human)" ; rdfs:comment "An RNA-binding protein 41 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000013799 , obo:PR_000029067 . obo:OBI_0001616 a rdfs:Class ; rdfs:label "specimen identifier"@en ; rdfs:comment "A CRID symbol denotes a specimen and used to distinguish one specimen from another in an investigation."@en ; rdfs:subClassOf obo:IAO_0000577 . obo:IAO_0000219 a rdf:Property ; rdfs:label "denotes"@en ; rdfs:range obo:OBI_0100051 . obo:GO_0051171 a rdfs:Class ; rdfs:label "regulation of nitrogen compound metabolic process" ; rdfs:comment "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving nitrogen or nitrogenous compounds." ; rdfs:subClassOf obo:GO_0019222 . obo:PR_000008044 a rdfs:Class ; rdfs:label "glycine receptor subunit alpha-3" ; rdfs:comment "A glycine receptor protein that is a translation product of the human GLRA3 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000044665 . obo:PR_000031874 a rdfs:Class ; rdfs:label "protein O-glucosyltransferase 2" ; rdfs:comment "A protein that is a translation product of the human POGLUT2 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:NCBITaxon_389147 a rdfs:Class ; rdfs:label "Bat coronavirus (BtCoV/A821/2005)" ; rdfs:subClassOf obo:NCBITaxon_389126 . obo:PR_Q96ER3 a rdfs:Class ; rdfs:label "protein SAAL1 (human)" ; rdfs:comment "A protein SAAL1 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000014427 , obo:PR_000029067 . obo:CHEBI_46848 a rdfs:Class ; rdfs:label "N-arylpiperazine" ; rdfs:subClassOf obo:CHEBI_26144 , obo:CHEBI_33860 , obo:CHEBI_50996 . obo:PR_Q07869 a rdfs:Class ; rdfs:label "peroxisome proliferator-activated receptor alpha (human)" ; rdfs:comment "A peroxisome proliferator-activated receptor alpha that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000013056 , obo:PR_000029067 . obo:CIDO_0000352 a rdfs:Class ; rdfs:label "COVID19 NGS diagnostic assay"@en ; rdfs:comment "a COVID-19 nucleic acid diagnostic assay using Next Genergation Sequence technology to detect virus RNA sequence."@en ; rdfs:subClassOf obo:CIDO_0000259 . obo:PR_000003107 a rdfs:Class ; rdfs:label "mitogen-activated protein kinase 14" ; rdfs:comment "A map kinase p38 that is a translation product of the human MAPK14 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000003106 . obo:CHEBI_50114 a rdfs:Class ; rdfs:label "estrogen" ; rdfs:comment "A hormone that stimulates or controls the development and maintenance of female sex characteristics in mammals by binding to oestrogen receptors. The oestrogens are named for their importance in the oestrous cycle. The oestrogens that occur naturally in the body, notably estrone, estradiol, estriol, and estetrol are steroids. Other compounds with oestrogenic activity are produced by plants (phytoestrogens) and fungi (mycoestrogens); synthetic compounds with oestrogenic activity are known as xenoestrogens." ; rdfs:subClassOf obo:CHEBI_50112 . obo:CHEBI_35780 a rdfs:Class ; rdfs:label "phosphate ion" ; rdfs:comment "A phosphorus oxoanion that is the conjugate base of phosphoric acid." ; rdfs:subClassOf obo:CHEBI_33461 . obo:PR_Q13131 a rdfs:Class ; rdfs:label "5'-AMP-activated protein kinase catalytic subunit alpha-1 (human)" ; rdfs:comment "A 5'-AMP-activated protein kinase catalytic subunit alpha-1 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000013218 , obo:PR_000029067 . obo:NCBITaxon_32524 a rdfs:Class ; rdfs:label "Amniota" ; rdfs:subClassOf obo:NCBITaxon_117571 , obo:NCBITaxon_32523 . a rdfs:Class ; rdfs:label "Clinical Kinetics [PK]" ; rdfs:subClassOf obo:BFO_0000015 . obo:VO_0000012 a rdfs:Class ; rdfs:label "vaccine-induced B cell mediated immunity" ; rdfs:subClassOf obo:VO_0000135 . obo:HP_0012531 a rdfs:Class ; rdfs:label "Pain" ; rdfs:comment "An unpleasant sensory and emotional experience associated with actual or potential tissue damage, or described in terms of such damage." ; rdfs:subClassOf obo:HP_0025142 . obo:OGMS_0000090 a rdfs:Class ; rdfs:label "treatment" ; rdfs:comment "A processual entity whose completion is hypothesized (by a healthcare provider) to alleviate the signs and symptoms associated with a disorder"@en ; rdfs:subClassOf obo:OBI_0000011 . obo:PR_000002040 a rdfs:Class ; rdfs:label "integrin beta-1" ; rdfs:comment "An integrin beta that is a translation product of the human ITGB1 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000001861 . obo:CHEBI_32915 a rdfs:Class ; rdfs:label "cetylpyridinium chloride" ; rdfs:comment "A pyridinium salt that has N-hexadecylpyridinium as the cation and chloride as the anion. It has antiseptic properties and is used in solutions or lozenges for the treatment of minor infections of the mouth and throat." ; rdfs:subClassOf obo:CHEBI_23114 , obo:CHEBI_36094 . obo:CIDO_0000233 a rdfs:Class ; rdfs:label "SARS-CoV-2 clade V virus"@en ; rdfs:comment "A SARS-CoV-2 variant virus that has a signature variant of the ORF3a coding protein NS3-G251." ; rdfs:subClassOf obo:CIDO_0000405 . a rdfs:Class ; rdfs:label "Piperidines [Chemical/Ingredient]" ; rdfs:subClassOf . obo:NCBITaxon_1788486 a rdfs:Class ; rdfs:label "Rhinolophus bat coronavirus BtCoV/3772" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:DOID_0070088 a rdfs:Class ; rdfs:label "schizophrenia 12" ; rdfs:comment "A schizophrenia that has_material_basis_in a mutation on chromosome 1p36.2." ; rdfs:subClassOf obo:DOID_0050736 , obo:DOID_5419 . obo:CIDO_0000470 a rdfs:Class ; rdfs:label "FSPFNSLLCGDIVSG" ; rdfs:comment "A coronavirus epitope that is part of some S protein from HCoV NL63 composed of the following amino acids FSPFNSLLCGDIVSG" ; rdfs:subClassOf obo:CIDO_0000449 . a rdfs:Class ; rdfs:label "Glomerulonephritis [Disease/Finding]" ; rdfs:subClassOf . obo:PR_000002094 a rdfs:Class ; rdfs:label "C-C motif chemokine 5" ; rdfs:comment "A C/C-C motif small inducible chemokine that is a translation product of the human CCL5 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000001808 . obo:PR_000001673 a rdfs:Class ; rdfs:label "lysophospholipid (S1P) receptor" ; rdfs:comment "An LPAR1/S1PR1-like lysophospholipid receptor that is a translation product of the human S1PR1, S1PR2, S1PR3, S1PR4, or S1PR5 genes, 1:1 orthologs thereof, or a semi-ortholog thereof. The active form binds sphingosine 1-phosphate (S1P). S1P is a bioactive lysophospholipid that elicits diverse physiological effects on most types of cells and tissues." ; rdfs:subClassOf obo:PR_000001427 . obo:CIDO_0000259 a rdfs:Class ; rdfs:label "COVID-19 nucleic acid diagnostic assay"@en ; rdfs:comment "A COVID-19 diagnosti ssay that uses a nucleic acid sample" ; rdfs:subClassOf obo:CIDO_0000258 . obo:OBI_1110034 a rdfs:Class ; rdfs:label "antigen"@en ; rdfs:comment "is a material entity that has the antigen role"@en ; rdfs:subClassOf obo:BFO_0000040 . obo:UBERON_0000062 a rdfs:Class ; rdfs:label "organ" ; rdfs:comment "Anatomical structure that performs a specific function or group of functions [WP]." ; rdfs:subClassOf obo:UBERON_0010000 . obo:GO_0050801 a rdfs:Class ; rdfs:label "ion homeostasis" ; rdfs:comment "Any process involved in the maintenance of an internal steady state of ions within an organism or cell." ; rdfs:subClassOf obo:GO_0048878 . obo:PR_000027961 a rdfs:Class ; rdfs:label "RING-box protein 1 related protein" ; rdfs:comment "A RING-box protein that is a translation product of the human RBX1 gene, the Arabidopsis thaliana RBX1A or RBX1B genes, or 1:1 orthologs thereof. It contains a copy of the RING-H2 zinc finger (Pfam:PF12678) domain." ; rdfs:subClassOf obo:PR_000000004 . obo:VO_0005342 a rdfs:Class ; rdfs:label "ChAd-triCoV/Mac"@en ; rdfs:comment "A SARS-CoV-2 replication deficient chimpanzee adenovirus 68 vector vaccine expressing the spike, nucleocapsid and RNA polymerase proteins." ; rdfs:subClassOf obo:VO_0005200 . obo:CIDO_0020122 a rdfs:Class ; rdfs:label "DTPM COVID-19 RT-PCR Test" ; rdfs:seeAlso ; rdfs:subClassOf obo:CIDO_0000454 . obo:PR_O15146 a rdfs:Class ; rdfs:label "muscle, skeletal receptor tyrosine-protein kinase (human)" ; rdfs:comment "A muscle, skeletal receptor tyrosine-protein kinase that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000010780 , obo:PR_000029067 . obo:NCBITaxon_2724161 a rdfs:Class ; rdfs:label "unclassified Buldecovirus" ; rdfs:subClassOf obo:NCBITaxon_2509474 . obo:GO_0010941 a rdfs:Class ; rdfs:label "regulation of cell death" ; rdfs:comment "Any process that modulates the rate or frequency of cell death. Cell death is the specific activation or halting of processes within a cell so that its vital functions markedly cease, rather than simply deteriorating gradually over time, which culminates in cell death." ; rdfs:subClassOf obo:GO_0050794 . obo:PR_000012515 a rdfs:Class ; rdfs:label "3-phosphoinositide-dependent protein kinase 1" ; rdfs:comment "A protein that is a translation product of the human PDPK1 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:HP_0001663 a rdfs:Class ; rdfs:label "Ventricular fibrillation" ; rdfs:comment "Uncontrolled contractions of muscles fibers in the left ventricle not producing contraction of the left ventricle. Ventricular fibrillation usually begins with a ventricular premature contraction and a short run of rapid ventricular tachycardia degenerating into uncoordinating ventricular fibrillations." ; rdfs:subClassOf obo:HP_0004308 . obo:CHEBI_24867 a rdfs:Class ; rdfs:label "monoatomic ion" ; rdfs:subClassOf obo:CHEBI_24870 , obo:CHEBI_33238 . obo:VO_0005206 a rdfs:Class ; rdfs:label "Matrix-M vaccine adjuvant"@en ; rdfs:comment "A vaccine adjuvant comprised of 40 nm nanoparticles composed of Quillaja saponins, cholesterol and phospholipid." ; rdfs:subClassOf obo:VO_0001267 . obo:CIDO_0001209 a rdfs:Class ; rdfs:label "Multiple Real-Time PCR Kit for Detection of 2019-nCoV. (Shanghai ZJ Bio-Tech Co., Ltd.)" ; rdfs:comment "Manufacturor: Shanghai ZJ Bio-Tech Co., Ltd. 上海之江生物科技股份有限公司" ; rdfs:subClassOf obo:CIDO_0000021 . obo:OBI_2000010 a rdfs:Class ; rdfs:label "chorionic villus specimen" ; rdfs:comment "A specimen that is derived from some chorionic villus " ; rdfs:subClassOf obo:OBI_0001479 . obo:CIDO_0001050 a rdfs:Class ; rdfs:label "SARS-CoV2 orf9c protein binding to human ERMP1" ; rdfs:comment "SARS-CoV2 orf9c protein binding to human ERMP1, as evidented by an affinity-purification mass spectrometry experiment" ; rdfs:subClassOf obo:CIDO_0000054 . obo:PR_000029340 a rdfs:Class ; rdfs:label "coiled-coil domain-containing protein 86" ; rdfs:comment "A protein that is a translation product of the human CCDC86 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:NCBITaxon_33737 a rdfs:Class ; rdfs:label "Porcine transmissible gastroenteritis coronavirus strain Miller" ; rdfs:subClassOf obo:NCBITaxon_11149 . obo:PR_000029502 a rdfs:Class ; rdfs:label "FYVE and coiled-coil domain-containing protein 1" ; rdfs:comment "A protein that is a translation product of the human FYCO1 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:MPATH_429 a rdfs:Class ; rdfs:label "myxomatous tumor" ; rdfs:comment "Neoplasms resembling primitive mesenchymal tissue with a soft mucous matrix." ; rdfs:subClassOf obo:MPATH_603 . obo:NCBITaxon_2729735 a rdfs:Class ; rdfs:label "unclassified Hibecovirus" ; rdfs:subClassOf obo:NCBITaxon_2509486 . a rdfs:Class ; rdfs:label "Immunologic and Biological Factors [MoA]" ; rdfs:subClassOf . obo:DRON_00000010 a rdfs:Class ; rdfs:label "portion of emulsion"@en ; rdfs:comment "a portion of colloid where both the dispersed material and the continuous medium are liquids"@en ; rdfs:subClassOf obo:DRON_00000009 . obo:DRON_00011912 a rdfs:Class ; rdfs:label "Hydroxyprogesterone" ; rdfs:subClassOf obo:OBI_0000047 . obo:PR_P57059 a rdfs:Class ; rdfs:label "serine/threonine-protein kinase SIK1 (human)" ; rdfs:comment "A serine/threonine-protein kinase SIK1 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000014870 , obo:PR_000029067 . obo:CHEBI_48589 a rdfs:Class ; rdfs:label "piperidones" ; rdfs:subClassOf obo:CHEBI_26151 , obo:CHEBI_36963 . obo:NCBITaxon_871680 a rdfs:Class ; rdfs:label "Feline coronavirus UU21" ; rdfs:subClassOf obo:NCBITaxon_12663 . obo:GO_0009314 a rdfs:Class ; rdfs:label "response to radiation" ; rdfs:comment "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an electromagnetic radiation stimulus. Electromagnetic radiation is a propagating wave in space with electric and magnetic components. These components oscillate at right angles to each other and to the direction of propagation." ; rdfs:subClassOf obo:GO_0009628 . a rdfs:Class ; rdfs:label "Cellular Synthetic Activity Alteration [PE]" ; rdfs:subClassOf . a rdfs:Class ; rdfs:label "Increased Norepinephrine Activity [PE]" ; rdfs:subClassOf . obo:NCBITaxon_293320 a rdfs:Class ; rdfs:label "SARS coronavirus PC4-205" ; rdfs:subClassOf obo:NCBITaxon_694009 . obo:VO_0005351 a rdfs:Class ; rdfs:label "IN-B009"@en ; rdfs:comment "A SARS-CoV-2 subunit vaccine by HK inno.N Corporation" ; rdfs:subClassOf obo:VO_0005202 . obo:PR_000013230 a rdfs:Class ; rdfs:label "cAMP-dependent protein kinase type II-alpha regulatory subunit" ; rdfs:comment "A protein that is a translation product of the human PRKAR2A gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:NCBITaxon_1699332 a rdfs:Class ; rdfs:label "Myotis Bat Alphacoronavirus strain YNXY_31C" ; rdfs:subClassOf obo:NCBITaxon_366617 . a rdfs:Class ; rdfs:label "Parasitic Diseases, Animal [Disease/Finding]" ; rdfs:subClassOf . obo:PR_000045385 a rdfs:Class ; rdfs:label "M gene translation product (Influenza A virus (strain A/Puerto Rico/8/1934 H1N1))" ; rdfs:comment "An influenzavirus M gene translation product that is encoded in the genome of the H1N1 strain A/Puerto Rico/8/1934." ; rdfs:subClassOf obo:PR_000036197 , obo:PR_000037023 . obo:CHEBI_32660 a rdfs:Class ; rdfs:label "asparaginate" ; rdfs:comment "An alpha-amino-acid anion that is the conjugate base of asparagine, arising from deprotonation of the carboxy group." ; rdfs:subClassOf obo:CHEBI_33558 . obo:NCBITaxon_1146857 a rdfs:Class ; rdfs:label "Bat coronavirus M.nattereri/UK/Sav/1106A" ; rdfs:subClassOf obo:NCBITaxon_366617 . obo:NCBITaxon_1503292 a rdfs:Class ; rdfs:label "BtRf-AlphaCoV/HuB2013" ; rdfs:subClassOf obo:NCBITaxon_2501926 . obo:CHEBI_37933 a rdfs:Class ; rdfs:label "4aH-phenothiazine" ; rdfs:subClassOf obo:CHEBI_37932 . obo:OBI_0000086 a rdfs:Class ; rdfs:label "reagent role"@en ; rdfs:comment "A role inhering in a biological or chemical entity that is intended to be applied in a scientific technique to participate (or have molecular components that participate) in a chemical reaction that facilitates the generation of data about some entity distinct from the bearer, or the generation of some specified material output distinct from the bearer."@en ; rdfs:subClassOf obo:BFO_0000023 . a rdfs:Class ; rdfs:label "Ascariasis [Disease/Finding]" ; rdfs:subClassOf . obo:CHEBI_17115 a rdfs:Class ; rdfs:label "L-serine" ; rdfs:comment "The L-enantiomer of serine." ; rdfs:subClassOf obo:CHEBI_15705 , obo:CHEBI_17822 , obo:CHEBI_26650 , obo:CHEBI_83813 . obo:PR_Q9Y4L1 a rdfs:Class ; rdfs:label "hypoxia up-regulated protein 1 (human)" ; rdfs:comment "A hypoxia up-regulated protein 1 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000008853 , obo:PR_000029067 . obo:CIDO_0000681 a rdfs:Class ; rdfs:label "N764K in SARS-CoV-2 S protein" ; rdfs:comment "An AA mutation or AA variant that has mutated an amino acid at position 764 into a lysine in S protein." ; rdfs:subClassOf obo:CIDO_0000595 . obo:CHEBI_25903 a rdfs:Class ; rdfs:label "peptide antibiotic" ; rdfs:comment "A chemically diverse class of peptides that exhibit antimicrobial properties." ; rdfs:subClassOf obo:CHEBI_16670 . obo:CHEBI_38337 a rdfs:Class ; rdfs:label "pyrimidone" ; rdfs:comment "A pyrimidine carrying one or more oxo substituents." ; rdfs:subClassOf obo:CHEBI_39447 . obo:CHEBI_25248 a rdfs:Class ; rdfs:label "methyl ester" ; rdfs:comment "Any carboxylic ester resulting from the formal condensation of a carboxy group with methanol." ; rdfs:subClassOf obo:CHEBI_33308 . obo:NCBITaxon_903609 a rdfs:Class ; rdfs:label "Kenya bat coronavirus BtKY71" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:GO_0030097 a rdfs:Class ; rdfs:label "hemopoiesis" ; rdfs:comment "The process whose specific outcome is the progression of the myeloid and lymphoid derived organ/tissue systems of the blood and other parts of the body over time, from formation to the mature structure. The site of hemopoiesis is variable during development, but occurs primarily in bone marrow or kidney in many adult vertebrates." ; rdfs:subClassOf obo:GO_0048513 . obo:VO_0001355 a rdfs:Class ; rdfs:label "emulsion vaccine adjuvant" ; rdfs:subClassOf obo:VO_0000580 . obo:PR_Q08431 a rdfs:Class ; rdfs:label "lactadherin (human)" ; rdfs:comment "A lactadherin that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000010367 , obo:PR_000029067 . obo:PR_000050266 a rdfs:Class ; rdfs:label "spike glycoprotein, signal peptide removed form (SARS-CoV-2)" ; rdfs:comment "A spike glycoprotein (SARS-CoV-2) that has had the signal peptide removed. UniProtKB:P0DTC2, 13-1273." ; rdfs:subClassOf obo:PR_P0DTC2 . obo:CHEBI_35554 a rdfs:Class ; rdfs:label "cardiovascular drug" ; rdfs:comment "A drug that affects the rate or intensity of cardiac contraction, blood vessel diameter or blood volume." ; rdfs:subClassOf obo:CHEBI_23888 . obo:GO_0051241 a rdfs:Class ; rdfs:label "negative regulation of multicellular organismal process" ; rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of an organismal process, the processes pertinent to the function of an organism above the cellular level; includes the integrated processes of tissues and organs." ; rdfs:subClassOf obo:GO_0048519 , obo:GO_0051239 . obo:CIDO_0020237 a rdfs:Class ; rdfs:label "Platelia SARS-CoV-2 Total Ab assay" ; rdfs:seeAlso ; rdfs:subClassOf obo:CIDO_0000454 . obo:CIDO_0000507 a rdfs:Class ; rdfs:label "GIFAKVKNTKVIKDR" ; rdfs:comment "A coronavirus epitope that is part of some S protein from HCoV OC43 composed of the following amino acids GIFAKVKNTKVIKDR" ; rdfs:subClassOf obo:CIDO_0000452 . obo:NCBITaxon_235413 a rdfs:Class ; rdfs:label "SARS coronavirus Sin2677" ; rdfs:subClassOf obo:NCBITaxon_694009 . obo:CHEBI_47790 a rdfs:Class ; rdfs:label "furofuran" ; rdfs:comment "Organic heterobicyclic compounds containing a two furan rings ortho-fused to each other." ; rdfs:subClassOf obo:CHEBI_27171 , obo:CHEBI_38104 . obo:PR_000013223 a rdfs:Class ; rdfs:label "cAMP-dependent protein kinase catalytic subunit beta" ; rdfs:comment "A cAMP-dependent protein kinase catalytic subunit that is a translation product of the human PRKACB gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000029188 . obo:PR_Q13523 a rdfs:Class ; rdfs:label "serine/threonine-protein kinase PRP4 homolog (human)" ; rdfs:comment "A serine/threonine-protein kinase PRP4 that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000013286 , obo:PR_000029067 . obo:PR_000003215 a rdfs:Class ; rdfs:label "mitogen-activated protein kinase kinase kinase 1" ; rdfs:comment "A protein that is a translation product of the human MAP3K1 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:GO_0051641 a rdfs:Class ; rdfs:label "cellular localization" ; rdfs:comment "A cellular localization process whereby a substance or cellular entity, such as a protein complex or organelle, is transported to, and/or maintained in, a specific location within a cell including the localization of substances or cellular entities to the cell membrane." ; rdfs:subClassOf obo:GO_0009987 , obo:GO_0051179 . obo:GO_0002682 a rdfs:Class ; rdfs:label "regulation of immune system process" ; rdfs:comment "Any process that modulates the frequency, rate, or extent of an immune system process." ; rdfs:subClassOf obo:GO_0050789 . a rdfs:Class ; rdfs:label "Fatty Acids, Volatile [Chemical/Ingredient]" ; rdfs:subClassOf . obo:NCBITaxon_1146851 a rdfs:Class ; rdfs:label "Bat coronavirus M.daubentonii/UK/Wyt/991C" ; rdfs:subClassOf obo:NCBITaxon_366617 . obo:CHEBI_33304 a rdfs:Class ; rdfs:label "chalcogen molecular entity" ; rdfs:comment "Any p-block molecular entity containing a chalcogen." ; rdfs:subClassOf obo:CHEBI_33675 . obo:PR_000030474 a rdfs:Class ; rdfs:label "ER membrane protein complex subunit 1" ; rdfs:comment "A protein that is a translation product of the human EMC1 gene or a 1:1 ortholog thereof." ; rdfs:subClassOf obo:PR_000000001 . obo:NCBITaxon_931913 a rdfs:Class ; rdfs:label "Alphacoronavirus Eptesicus fuscus/Appalachian Ridge/P2-21252/IT/USA/2009" ; rdfs:subClassOf obo:NCBITaxon_366617 . obo:PR_000001349 a rdfs:Class ; rdfs:label "fibroblast growth factor receptor" ; rdfs:comment "A protein with an extracellular region containing three copies of the Immunoglobulin domain (Pfam:PF00047), a single transmembrane region, and an intracellular region containing a Protein tyrosine kinase domain (Pfam:PF07714). Its active form binds fibroblast growth factor (FGF). FGFs and its receptor comprise a signaling system that is conserved throughout metazoan evolution." ; rdfs:subClassOf obo:PR_000000001 . obo:NCBITaxon_627436 a rdfs:Class ; rdfs:label "Feline coronavirus UU9" ; rdfs:subClassOf obo:NCBITaxon_12663 . obo:NCBITaxon_681856 a rdfs:Class ; rdfs:label "Kenya bat coronavirus BtKY09" ; rdfs:subClassOf obo:NCBITaxon_2664420 . obo:CHEBI_140377 a rdfs:Class ; rdfs:label "(2S)-flavan-4-one" ; rdfs:comment "Any flavanone in which the chiral centre at position 2 has S-configuration." ; rdfs:subClassOf obo:CHEBI_28863 . a rdfs:Class ; rdfs:label "Central Nervous System Neoplasms [Disease/Finding]" ; rdfs:subClassOf . a rdfs:Class ; rdfs:label "TRIFLUPROMAZINE" ; rdfs:subClassOf . obo:CHEBI_8024 a rdfs:Class ; rdfs:label "perindopril" ; rdfs:comment "An alpha-amino acid ester that is the ethyl ester of N-{(2S)-1-[(2S,3aS,7aS)-2-carboxyoctahydro-1H-indol-1-yl]-1-oxopropan-2-yl}-L-norvaline" ; rdfs:subClassOf obo:CHEBI_23990 , obo:CHEBI_27171 , obo:CHEBI_36244 , obo:CHEBI_46874 . obo:CIDO_0020059 a rdfs:Class ; rdfs:label "Biomeme SARS-CoV-2 Real-Time RT-PCR Test" ; rdfs:seeAlso ; rdfs:subClassOf obo:CIDO_0000454 . obo:OGG_3000003569 a rdfs:Class ; rdfs:label "IL6" ; rdfs:comment "Other designations: B-cell differentiation factor|B-cell stimulatory factor 2|BSF-2|CDF|CTL differentiation factor|IFN-beta-2|hybridoma growth factor|interferon beta-2|interferon, beta 2|interleukin 6 (interferon, beta 2)|interleukin BSF-2|interleukin-6" ; rdfs:subClassOf obo:OGG_2060009606 . obo:OBI_1110045 a rdfs:Class ; rdfs:label "disposition to be bound by an adaptive immune receptor"@en ; rdfs:comment "Is the disposition borne by a material entity that is realized in a process of being bound by a adaptive immune receptor."@en ; rdfs:subClassOf obo:BFO_0000016 . obo:NCBITaxon_1346302 a rdfs:Class ; rdfs:label "Betacoronavirus BtCoV/Rhi_fer/It1/ITA/2009" ; rdfs:subClassOf obo:NCBITaxon_696098 . obo:OBI_0000873 a rdfs:Class ; rdfs:label "pre-mortem specimen" ; rdfs:comment "a specimen that was taken from a live organism" ; rdfs:subClassOf obo:OBI_0001506 . a rdfs:Class ; rdfs:label "Vascular Alterations [PE]" ; rdfs:subClassOf . obo:PR_Q96F46 a rdfs:Class ; rdfs:label "interleukin-17 receptor A (human)" ; rdfs:comment "An interleukin-17 receptor A that is encoded in the genome of human." ; rdfs:subClassOf obo:PR_000001375 , obo:PR_000029067 . obo:NCBITaxon_1934038 a rdfs:Class ; rdfs:label "Rynchops niger coronavirus" ; rdfs:subClassOf obo:NCBITaxon_1232736 . a rdf:Property ; rdfs:label "Display_Name" ; rdfs:range xsd:string . a rdf:Property ; rdfs:label "FDA_UNII" ; rdfs:range xsd:string . a rdf:Property ; rdfs:label "Level" ; rdfs:range . a rdf:Property ; rdfs:label "MeSH_CUI" ; rdfs:range xsd:string . a rdf:Property ; rdfs:label "MeSH_DUI" ; rdfs:range xsd:string . a rdf:Property ; rdfs:label "MeSH_Definition" ; rdfs:range xsd:string . a rdf:Property ; rdfs:label "MeSH_Name" ; rdfs:range xsd:string . a rdf:Property ; rdfs:label "NUI" ; rdfs:range xsd:string . a rdf:Property ; rdfs:label "RxNorm_CUI" ; rdfs:range xsd:string . a rdf:Property ; rdfs:label "RxNorm_Name" ; rdfs:range xsd:string . a rdf:Property ; rdfs:label "SNOMED_CID" ; rdfs:range xsd:string . a rdf:Property ; rdfs:label "Status" ; rdfs:range . a rdf:Property ; rdfs:label "Synonym" ; rdfs:range xsd:string . a rdf:Property ; rdfs:label "UMLS_CUI" ; rdfs:range xsd:string . a rdf:Property ; rdfs:label "VANDF_Record" ; rdfs:range xsd:string . a rdf:Property ; rdfs:label "VUID" ; rdfs:range xsd:string . a rdf:Property ; rdfs:range xsd:string . obo:BFO_0000070 a rdf:Property ; rdfs:label "specifically depends on at all times"@en ; rdfs:range xsd:string ; rdfs:subPropertyOf obo:BFO_0000169 . obo:BFO_0000071 a rdf:Property ; rdfs:label "has granular part"@en ; rdfs:range xsd:string ; rdfs:subPropertyOf obo:BFO_0000051 . obo:BFO_0000125 a rdf:Property ; rdfs:label "has specific dependent at some time"@en ; rdfs:range xsd:string . obo:BFO_0000158 a rdf:Property ; rdfs:label "bearer of at all times"@en ; rdfs:comment "b bearer_of c at t =Def. c s-depends_on b at t & b is an independent continuant that is not a spatial region. (axiom label in BFO2 Reference: [053-004])"@en ; rdfs:range obo:BFO_0000020 ; rdfs:subPropertyOf obo:BFO_0000168 . obo:BFO_0000168 a rdf:Property ; rdfs:label "has specific dependent at all times"@en ; rdfs:range xsd:string ; rdfs:subPropertyOf obo:BFO_0000125 . obo:BFO_0000179 a rdf:Property ; rdfs:label "BFO OWL specification label" ; rdfs:comment "Relates an entity in the ontology to the name of the variable that is used to represent it in the code that generates the BFO OWL file from the lispy specification."@en ; rdfs:range xsd:string . obo:BFO_0000180 a rdf:Property ; rdfs:label "BFO CLIF specification label" ; rdfs:comment "Relates an entity in the ontology to the term that is used to represent it in the the CLIF specification of BFO2"@en ; rdfs:range xsd:string . obo:CIDO_0000009 a rdf:Property ; rdfs:label "Chinese label" ; rdfs:range xsd:string . obo:CIDO_0000032 a rdf:Property ; rdfs:label "assay performed at"@en ; rdfs:comment "An object property that represents a relation between an assay and an organization and the assay is performed at the organization such as a company or hospital" ; rdfs:range . obo:CIDO_0000041 a rdf:Property ; rdfs:label "FDA EUA laboratory,company or organization"@en ; rdfs:comment "An annotation property that represents a laboratory, company or organization authorized by FDA emergency use authorization (EUA) to perform an assay such as a SARS-CoV-2 RT-PCR assay." ; rdfs:range xsd:string . obo:CIDO_0000061 a rdf:Property ; rdfs:label "has binding participant"@en ; rdfs:comment "An object property between a binding process and a paritipant where the participant is one input of the binding process." ; rdfs:range xsd:string ; rdfs:subPropertyOf obo:RO_0000057 . obo:CIDO_0000139 a rdf:Property ; rdfs:label "chemical effective against virus"@en ; rdfs:comment "An object property that represents a relation between a chemical entity and a virus where the chemical has an effective role against viral infection" ; rdfs:range . obo:CIDO_0000142 a rdf:Property ; rdfs:label "chemical effective in vivo against virus"@en ; rdfs:comment "An object property that represents a relation between a chemical entity and a virus where the chemical has an effective role against viral infection in vivo" ; rdfs:range xsd:string ; rdfs:subPropertyOf obo:CIDO_0000139 . obo:CIDO_0000143 a rdf:Property ; rdfs:label "chemical inhibits in vivo invasion of virus"@en ; rdfs:comment "An object property that represents a relation between a chemical entity and a virus where the chemical has an effective role against viral invasion in vivo" ; rdfs:range xsd:string ; rdfs:subPropertyOf obo:CIDO_0000149 , obo:CIDO_0000142 . obo:CIDO_0000146 a rdf:Property ; rdfs:label "chemical modulates response against virus"@en ; rdfs:comment "An object property that represents a relation between a chemical entity and a virus where the chemical has an effective role in modulating host response against virual infection" ; rdfs:range xsd:string ; rdfs:subPropertyOf obo:CIDO_0000139 . obo:CIDO_0000147 a rdf:Property ; rdfs:label "chemical modulates response in vivo against virus"@en ; rdfs:comment "An object property that represents a relation between a chemical entity and a virus where the chemical has an effective role in modulating host response against viral infection in vivo" ; rdfs:range xsd:string ; rdfs:subPropertyOf obo:CIDO_0000146 , obo:CIDO_0000142 . obo:CIDO_0000149 a rdf:Property ; rdfs:label "chemical inhibits invasion of virus"@en ; rdfs:comment "An object property that represents a relation between a chemical entity and a virus where the chemical has an effective role against virual invasion" ; rdfs:range xsd:string ; rdfs:subPropertyOf obo:CIDO_0000139 . obo:CIDO_0000150 a rdf:Property ; rdfs:label "chemical inhibits replication of virus"@en ; rdfs:comment "An object property that represents a relation between a chemical entity and a virus where the chemical has an effective role against virual replication" ; rdfs:range xsd:string ; rdfs:subPropertyOf obo:CIDO_0000139 . obo:CIDO_0000174 a rdf:Property ; rdfs:label "drug effective against virus"@en ; rdfs:comment "An object property that represents a relation between a drug and a virus where the drug has an effective role against viral infection" ; rdfs:range . obo:CIDO_0000178 a rdf:Property ; rdfs:label "has text mining keywords"@en ; rdfs:comment "An annotation property that provides one or more keywords useful for text mining of the indicated ontology term." ; rdfs:range xsd:string . obo:CIDO_0000188 a rdf:Property ; rdfs:label "induces in vivo production of"@en ; rdfs:comment "An object property between material entity a and b where a is capable of inducing the production of b in vivo." ; rdfs:range xsd:string ; rdfs:subPropertyOf obo:RO_0002410 . obo:CIDO_0000220 a rdf:Property ; rdfs:label "causal relation related to phenotype"@en ; rdfs:range xsd:string ; rdfs:subPropertyOf obo:RO_0002410 . obo:CIDO_0000223 a rdf:Property ; rdfs:label "causal process for agent"@en ; rdfs:range xsd:string ; rdfs:subPropertyOf obo:RO_0002595 . obo:CIDO_0000358 a rdf:Property ; rdfs:label "pathway susceptibly regulated in"@en ; rdfs:comment "An object property that represents a relation between a pathway (biological process) and a process in which the pathway is susceptibly to differential regulation in the process." ; rdfs:range . obo:CIDO_0000363 a rdf:Property ; rdfs:label "pathway susceptibly down-regulated in"@en ; rdfs:range xsd:string ; rdfs:subPropertyOf obo:CIDO_0000358 . obo:CIDO_0000385 a rdf:Property ; rdfs:label "interactive relatoin between material entities"@en ; rdfs:range xsd:string ; rdfs:subPropertyOf obo:RO_0002609 . obo:CIDO_0000391 a rdf:Property ; rdfs:label "susceptible to infection of"@en ; rdfs:range . obo:CIDO_0000392 a rdf:Property ; rdfs:label "susceptible to lethal infection of"@en ; rdfs:range xsd:string ; rdfs:subPropertyOf obo:CIDO_0000391 . obo:CIDO_0000393 a rdf:Property ; rdfs:label "has genetic mutation"@en ; rdfs:range . obo:CIDO_0000408 a rdf:Property ; rdfs:label "chemical has protein target as negative modulator"@en ; rdfs:comment "An object property that represents a relation between a chemical entity and a protein where the chemical entity can target the protein as a negative modulator. Note that the chemical entity is usually an active compound of a corresponding drug." ; rdfs:range xsd:string ; rdfs:subPropertyOf obo:CIDO_0000394 . obo:CIDO_0000411 a rdf:Property ; rdfs:label "chemical stimulates protein"@en ; rdfs:comment "An object property that represents a relation between a chemical entity and a protein where the chemical entity can target the protein as a stimulator. Note that the chemical entity is usually an active compound of a corresponding drug." ; rdfs:range xsd:string ; rdfs:subPropertyOf obo:CIDO_0000118 . obo:CIDO_0000456 a rdf:Property ; rdfs:label "wikidata_ID"@en ; rdfs:range xsd:string . obo:CIDO_0000603 a rdf:Property ; rdfs:label "has AA variant"@en ; rdfs:range . obo:CIDO_0000604 a rdf:Property ; rdfs:label "has relative risk with no vaccination"@en ; rdfs:range . obo:CIDO_0000605 a rdf:Property ; rdfs:label "has relative risk post-vaccination"@en ; rdfs:range . obo:CIDO_0000606 a rdf:Property ; rdfs:label "has relative risk post-boost-vaccination"@en ; rdfs:range . obo:CIDO_0000608 a rdf:Property ; rdfs:label "has AA mutation"@en ; rdfs:range . obo:CIDO_0000704 a rdf:Property ; rdfs:label "has characteristic AA mutation"@en ; rdfs:comment "An object property that defines a relation between a microbe variant and an AA mutation where the microbe (like SARS_CoV-2) variant has the AA mutation such that the microbe variant has an AA change that is used to identify a mircrobe variant. This is used over AA variant for deletions or nonsense mutations." ; rdfs:range xsd:string ; rdfs:subPropertyOf obo:CIDO_0000608 . obo:CIDO_0001082 a rdf:Property ; rdfs:label "device utilizes material"@en ; rdfs:range . obo:CIDO_0001089 a rdf:Property ; rdfs:label "PCR detects gene"@en ; rdfs:comment "A short-cut relation that represents a direct relationship between a PCR test and the target gene (or gene region) that the test is designed to amplify and detect the targeted gene or gene region." ; rdfs:range . obo:DRON_00010000 a rdf:Property ; rdfs:label "has_RxCUI" ; rdfs:range xsd:string . obo:IAO_0000111 a rdf:Property ; rdfs:label "editor preferred label" ; rdfs:comment "The concise, meaningful, and human-friendly name for a class or property preferred by the ontology developers. (US-English)"@en ; rdfs:range xsd:string . obo:IAO_0000112 a rdf:Property ; rdfs:label "example of usage" ; rdfs:comment "A phrase describing how a class name should be used. May also include other kinds of examples that facilitate immediate understanding of a class semantics, such as widely known prototypical subclasses or instances of the class. Although essential for high level terms, examples for low level terms (e.g., Affymetrix HU133 array) are not"@en ; rdfs:range xsd:string . obo:IAO_0000114 a rdf:Property ; rdfs:label "has curation status" ; rdfs:range xsd:string . obo:IAO_0000115 a rdf:Property ; rdfs:label "textual definition" ; rdfs:comment "The official definition." ; rdfs:range xsd:string . obo:IAO_0000116 a rdf:Property ; rdfs:label "editor note" ; rdfs:comment "An administrative note intended for its editor. It may not be included in the publication version of the ontology, so it should contain nothing necessary for end users to understand the ontology."@en ; rdfs:range xsd:string . obo:IAO_0000117 a rdf:Property ; rdfs:label "term editor" ; rdfs:comment "Name of editor entering the term in the file. The term editor is a point of contact for information regarding the term. The term editor may be, but is not always, the author of the definition, which may have been worked upon by several people"@en ; rdfs:range xsd:string . obo:IAO_0000118 a rdf:Property ; rdfs:label "alternative term" ; rdfs:comment "An alternative name for a class or property which means the same thing as the preferred name (semantically equivalent)"@en ; rdfs:range xsd:string . obo:IAO_0000119 a rdf:Property ; rdfs:label "definition source" ; rdfs:comment "Formal citation, e.g. identifier in external database to indicate / attribute source(s) for the definition. Free text indicate / attribute source(s) for the definition. EXAMPLE: Author Name, URI, MeSH Term C04, PUBMED ID, Wiki uri on 31.01.2007"@en ; rdfs:range xsd:string . obo:IAO_0000231 a rdf:Property ; rdfs:label "has obsolescence reason"@en ; rdfs:comment "Relates an annotation property to an obsolescence reason. The values of obsolescence reasons come from a list of predefined terms, instances of the class obsolescence reason specification."@en ; rdfs:range xsd:string . obo:IAO_0000232 a rdf:Property ; rdfs:label "curator notes" ; rdfs:comment "An administrative note of use for a curator but of no use for a user"@en ; rdfs:range xsd:string . obo:IAO_0000233 a rdf:Property ; rdfs:label "term tracker item" ; rdfs:comment "An IRI or similar locator for a request or discussion of an ontology term."@en ; rdfs:range xsd:string . obo:IAO_0000234 a rdf:Property ; rdfs:label "ontology term requester"@en ; rdfs:comment "The name of the person, project, or organization that motivated inclusion of an ontology term by requesting its addition."@en ; rdfs:range xsd:string . obo:IAO_0000412 a rdf:Property ; rdfs:label "imported from" ; rdfs:comment "For external terms/classes, the ontology from which the term was imported"@en ; rdfs:range xsd:string . obo:IAO_0000424 a rdf:Property ; rdfs:label "expand expression to" ; rdfs:range xsd:string . obo:IAO_0000589 a rdf:Property ; rdfs:label "OBO foundry unique label" ; rdfs:comment "An alternative name for a class or property which is unique across the OBO Foundry."@en ; rdfs:range xsd:string . obo:IAO_0000600 a rdf:Property ; rdfs:label "elucidation" ; rdfs:range xsd:string . obo:IAO_0000601 a rdf:Property ; rdfs:label "has associated axiom(nl)" ; rdfs:range xsd:string . obo:IAO_0000602 a rdf:Property ; rdfs:label "has associated axiom(fol)" ; rdfs:range xsd:string . obo:IAO_0100001 a rdf:Property ; rdfs:label "term replaced by" ; rdfs:range xsd:string . obo:ICO_0000092 a rdf:Property ; rdfs:label "term_mapping_to_NCIT"@en ; rdfs:range xsd:string . obo:NCIT_A11 a rdf:Property ; rdfs:label "Has_NICHD_Parent" ; rdfs:comment "A property created to allow the source NICHD to assign a parent to each concept with the intent of creating a hierarchy that includes only terms in which they are the contributing source." ; rdfs:range xsd:string . obo:NCIT_NHC0 a rdf:Property ; rdfs:label "code" ; rdfs:range xsd:string . obo:NCIT_P106 a rdf:Property ; rdfs:label "Semantic_Type" ; rdfs:comment "The semantic type describes the sort of thing or category to which a concept belongs in the context of the UMLS semantic network." ; rdfs:range xsd:string . obo:NCIT_P107 a rdf:Property ; rdfs:label "Display_Name" ; rdfs:comment "Provides an alternative Preferred Name for use in some NCI systems." ; rdfs:range xsd:string . obo:NCIT_P108 a rdf:Property ; rdfs:label "Preferred_Name" ; rdfs:comment "The word or phrase that NCI uses by preference to refer to the concept." ; rdfs:range xsd:string . obo:NCIT_P207 a rdf:Property ; rdfs:label "UMLS_CUI" ; rdfs:comment "Concept Unique Identifiers, or CUIs, are concept numbers assigned by the National Library of Medicine (NLM). If a concept in any NCI-maintained knowledgebase exists in the NLM Unified Medical Language System (UMLS), NCI includes the NLM CUI among the information we provide about the concept." ; rdfs:range xsd:string . obo:NCIT_P322 a rdf:Property ; rdfs:label "Contributing_Source" ; rdfs:comment "This property is used to indicate when a non-EVS entity has contributed to, and has a stake in, a concept. This is used where such entities, within or outside NCI, have indicated the need to be able to track their own concepts. A single concept can have multiple instances of this property if multiple entities have such a defined stake." ; rdfs:range xsd:string . obo:NCIT_P325 a rdf:Property ; rdfs:label "ALT_DEFINITION" ; rdfs:comment "English language definitions of what a source other than NCI means by the concept. These are limited to 1024 characters. They include information about the definition's source in a form that can easily be interpreted by software." ; rdfs:range xsd:string . obo:NCIT_P366 a rdf:Property ; rdfs:label "Legacy_Concept_Name" ; rdfs:comment "A retired unique concept identifier created and stored as Concept Name by legacy EVS software. Use of these values was long discouraged, but continued as late as 2009 when creation of new values ceased and Concept Name was retired. Legacy values are intended solely to help resolve and update earlier coding." ; rdfs:range xsd:string . obo:NCIT_P371 a rdf:Property ; rdfs:label "NICHD_Hierarchy_Term" ; rdfs:range xsd:string . obo:NCIT_P98 a rdf:Property ; rdfs:label "DesignNote" ; rdfs:comment "Design notes are notations made by NCI vocabulary curators. They are intended to provide supplemental, unstructured information to the user or additional insight about the concept." ; rdfs:range xsd:string . obo:OAE_0001849 a rdf:Property ; rdfs:label "Chinese translation"@en ; rdfs:comment "a chinese translation represents a chinese translation of the existing term." ; rdfs:range xsd:string . obo:OAE_0003232 a rdf:Property ; rdfs:label "adverse event outcome"@en ; rdfs:comment "an annotation property that represents the label of an adverse event" ; rdfs:range xsd:string . obo:OAE_0004334 a rdf:Property ; rdfs:label "has_MedDRA_id"@en ; rdfs:range xsd:string . obo:OBI_0000295 a rdf:Property ; rdfs:label "is_specified_input_of"@en ; rdfs:comment "A relation between a planned process and a continuant participating in that process that is not created during the process. The presence of the continuant during the process is explicitly specified in the plan specification which the process realizes the concretization of."@en ; rdfs:range obo:OBI_0000011 ; rdfs:subPropertyOf obo:RO_0000056 . obo:OBI_0000316 a rdf:Property ; rdfs:label "obsolete_has_role"@en ; rdfs:comment "A relation between a continuant C and a role R. The reciprocal relation of role_of." ; rdfs:range xsd:string ; rdfs:subPropertyOf . obo:OBI_0001847 a rdf:Property ; rdfs:label "ISA alternative term"@en ; rdfs:comment "An alternative term used by the ISA tools project (http://isa-tools.org)." ; rdfs:range xsd:string ; rdfs:subPropertyOf obo:IAO_0000118 . obo:OBI_0001886 a rdf:Property ; rdfs:label "NIAID GSCID-BRC alternative term"@en ; rdfs:comment "An alternative term used by the National Institute of Allergy and Infectious Diseases (NIAID) Genomic Sequencing Centers for Infectious Diseases (GSCID) and Bioinformatics Resource Centers (BRC)." ; rdfs:range xsd:string ; rdfs:subPropertyOf obo:IAO_0000118 . obo:OBI_0001937 a rdf:Property ; rdfs:label "has specified value" ; rdfs:comment "A relation between a value specification and a number that quantifies it." ; rdfs:range . obo:OBI_9991118 a rdf:Property ; rdfs:label "IEDB alternative term" ; rdfs:comment "An alternative term used by the IEDB." ; rdfs:range xsd:string ; rdfs:subPropertyOf obo:IAO_0000118 . obo:OGG_0000000004 a rdf:Property ; rdfs:label "symbol from nomenclature authority"@en ; rdfs:comment "the symbol assigned by the nomenclature authority" ; rdfs:range xsd:string . obo:OGG_0000000005 a rdf:Property ; rdfs:label "full name from nomenclature authority"@en ; rdfs:comment "the full name assigned by the nomenclature authority" ; rdfs:range xsd:string . obo:OGG_0000000006 a rdf:Property ; rdfs:label "NCBI GeneID"@en ; rdfs:comment "A GeneID in the NCBI Gene database " ; rdfs:range xsd:string . obo:OGG_0000000007 a rdf:Property ; rdfs:label "NCBI LocusTag"@en ; rdfs:comment "the NCBI LocusTag name of a gene " ; rdfs:range xsd:string . obo:OGG_0000000008 a rdf:Property ; rdfs:label "gene map location"@en ; rdfs:comment "the map location of a gene" ; rdfs:range xsd:string . obo:OGG_0000000009 a rdf:Property ; rdfs:label "modification date"@en ; rdfs:comment "a date of content modification" ; rdfs:range xsd:string . obo:OGG_0000000015 a rdf:Property ; rdfs:label "organism NCBITaxon ID"@en ; rdfs:comment "The NCBITaxon ontology ID of an organism." ; rdfs:range xsd:string . obo:OGG_0000000017 a rdf:Property ; rdfs:label "chromosome ID of gene"@en ; rdfs:comment "A chromosome ID where a gene is located." ; rdfs:range xsd:string . obo:OGG_0000000018 a rdf:Property ; rdfs:label "type of gene"@en ; rdfs:comment "an annotation property that specifies the type of a gene" ; rdfs:range xsd:string . obo:OGG_0000000019 a rdf:Property ; rdfs:label "nomenclature status"@en ; rdfs:comment "an annotation property that specifies a nomenclature status" ; rdfs:range xsd:string . obo:OGG_0000000030 a rdf:Property ; rdfs:label "has PubMed association"@en ; rdfs:comment "An annotation property that represents a gene's association with PubMed publication(s). " ; rdfs:range xsd:string . obo:OPMI_0000127 a rdf:Property ; rdfs:label "term mapping to NCIT ID"@en ; rdfs:comment "A subproperty of seeAlso that represents a NCIT identifier mapped to the specified term" ; rdfs:range xsd:string . obo:OPMI_0000128 a rdf:Property ; rdfs:label "term mapping to UMLS CUI"@en ; rdfs:comment "A subproperty of seeAlso that represents a UMLS CUI identifier mapped to the specified term" ; rdfs:range xsd:string . obo:OPMI_0000424 a rdf:Property ; rdfs:label "has sex-specific susceptibility to"@en ; rdfs:comment "An object property that represents a relation between a person with a biological sex and a process where the person has a specific susceptbility to a process" ; rdfs:range . obo:OPMI_0000434 a rdf:Property ; rdfs:label "alternative term in Chinese"@en ; rdfs:range xsd:string ; rdfs:subPropertyOf obo:IAO_0000118 . obo:OPMI_0000438 a rdf:Property ; rdfs:label "has increased susceptibility compared to male to"@en ; rdfs:comment "An object property that represents a relation between a person with a biological sex and a process where the person has an increased susceptbility to a process compared to corresponding male population" ; rdfs:range xsd:string ; rdfs:subPropertyOf obo:OPMI_0000424 . obo:OPMI_0000501 a rdf:Property ; rdfs:label "admitted from"@en ; rdfs:comment "An object property that represents a relation between a patient and a site from which the patient was admitted." ; rdfs:range . obo:OPMI_0000502 a rdf:Property ; rdfs:label "discharged to"@en ; rdfs:comment "An object property that represents a relation between a patient and a site to which the patient was discharged after a visit." ; rdfs:range . obo:RO_0000081 a rdf:Property ; rdfs:label "role of"@en ; rdfs:comment "a relation between a role and an independent continuant (the bearer), in which the role specifically depends on the bearer for its existence"@en ; rdfs:range xsd:string ; rdfs:subPropertyOf obo:RO_0000052 . obo:RO_0001001 a rdf:Property ; rdfs:label "derives into"@en ; rdfs:comment "a relation between two distinct material entities, the old entity and the new entity, in which the new entity begins to exist when the old entity ceases to exist, and the new entity inherits the significant portion of the matter of the old entity"@en ; rdfs:range . obo:RO_0001020 a rdf:Property ; rdfs:label "is allergic trigger for"@en ; rdfs:comment "A relation between a material entity and a condition (a phenotype or disease) of a host, in which the material entity is not part of the host, and is considered harmless to non-allergic hosts, and the condition results in pathological processes that include an abnormally strong immune response against the material entity." ; rdfs:range xsd:string ; rdfs:subPropertyOf obo:RO_0003302 . obo:RO_0001021 a rdf:Property ; rdfs:label "is autoimmune trigger for"@en ; rdfs:comment "A relation between a material entity and a condition (a phenotype or disease) of a host, in which the material entity is part of the host itself, and the condition results in pathological processes that include an abnormally strong immune response against the material entity." ; rdfs:range xsd:string ; rdfs:subPropertyOf obo:RO_0003302 . obo:RO_0001022 a rdf:Property ; rdfs:label "has allergic trigger"@en ; rdfs:comment "A relation between a condition (a phenotype or disease) of a host and a material entity, in which the material entity is not part of the host, and is considered harmless to non-allergic hosts, and the condition results in pathological processes that include an abnormally strong immune response against the material entity." ; rdfs:range xsd:string ; rdfs:subPropertyOf obo:RO_0003302 . obo:RO_0001023 a rdf:Property ; rdfs:label "has autoimmune trigger"@en ; rdfs:comment "A relation between a condition (a phenotype or disease) of a host and a material entity, in which the material entity is part of the host itself, and the condition results in pathological processes that include an abnormally strong immune response against the material entity." ; rdfs:range xsd:string ; rdfs:subPropertyOf obo:RO_0003302 . obo:RO_0001900 a rdf:Property ; rdfs:label "temporal interpretation" ; rdfs:comment "An assertion that holds between an OWL Object Property and a temporal interpretation that elucidates how OWL Class Axioms that use this property are to be interpreted in a temporal context." ; rdfs:seeAlso , ; rdfs:range xsd:string ; rdfs:subPropertyOf obo:RO_0002422 . obo:RO_0002010 a rdf:Property ; rdfs:label "regulates in other organism" ; rdfs:comment "x 'regulates in other organism' y if and only if: (x is the realization of a function to exert an effect on the frequency, rate or extent of y) AND (the agents of x are produced by organism o1 and the agents of y are produced by organism o2)." ; rdfs:range xsd:string ; rdfs:subPropertyOf obo:RO_0002418 . obo:RO_0002012 a rdf:Property ; rdfs:label "occurrent part of" ; rdfs:comment "A part of relation that applies only between occurrents." ; rdfs:range xsd:string ; rdfs:subPropertyOf obo:RO_0002418 , obo:BFO_0000050 . obo:RO_0002013 a rdf:Property ; rdfs:label "has regulatory component activity" ; rdfs:comment "A 'has regulatory component activity' B if A and B are GO molecular functions (GO_0003674), A has_component B and A is regulated by B." ; rdfs:range xsd:string ; rdfs:subPropertyOf obo:RO_0002334 , obo:RO_0002017 . obo:RO_0002014 a rdf:Property ; rdfs:label "has negative regulatory component activity" ; rdfs:comment "A relationship that holds between a GO molecular function and a component of that molecular function that negatively regulates the activity of the whole. More formally, A 'has regulatory component activity' B iff :A and B are GO molecular functions (GO_0003674), A has_component B and A is negatively regulated by B." ; rdfs:range xsd:string ; rdfs:subPropertyOf obo:RO_0002335 , obo:RO_0002013 . obo:RO_0002015 a rdf:Property ; rdfs:label "has positive regulatory component activity" ; rdfs:comment "A relationship that holds between a GO molecular function and a component of that molecular function that positively regulates the activity of the whole. More formally, A 'has regulatory component activity' B iff :A and B are GO molecular functions (GO_0003674), A has_component B and A is positively regulated by B." ; rdfs:range xsd:string ; rdfs:subPropertyOf obo:RO_0002336 , obo:RO_0002013 . obo:RO_0002016 a rdf:Property ; rdfs:label "has necessary component activity" ; rdfs:comment "A has necessary component activity B if A and B are GO molecular functions (GO_0003674), A has_component B and B is necessary for A. For example, ATPase coupled transporter activity has necessary component ATPase activity; transcript factor activity has necessary component DNA binding activity." ; rdfs:range xsd:string ; rdfs:subPropertyOf obo:RO_0002336 , obo:RO_0002017 . obo:RO_0002017 a rdf:Property ; rdfs:label "has component activity" ; rdfs:comment "A 'has component activity' B if A is A and B are molecular functions (GO_0003674) and A has_component B." ; rdfs:range xsd:string ; rdfs:subPropertyOf obo:RO_0002018 . obo:RO_0002018 a rdf:Property ; rdfs:label "has component process" ; rdfs:comment "w 'has process component' p if p and w are processes, w 'has part' p and w is such that it can be directly disassembled into into n parts p, p2, p3, ..., pn, where these parts are of similar type." ; rdfs:range xsd:string ; rdfs:subPropertyOf obo:RO_0002180 . obo:RO_0002022 a rdf:Property ; rdfs:label "directly regulated by" ; rdfs:comment "Process(P2) is directly regulated by process(P1) iff: P1 regulates P2 via direct physical interaction between an agent executing P1 (or some part of P1) and an agent executing P2 (or some part of P2). For example, if protein A has protein binding activity(P1) that targets protein B and this binding regulates the kinase activity (P2) of protein B then P1 directly regulates P2." ; rdfs:range xsd:string ; rdfs:subPropertyOf obo:RO_0002334 . obo:RO_0002023 a rdf:Property ; rdfs:label "directly negatively regulated by" ; rdfs:comment "Process(P2) is directly negatively regulated by process(P1) iff: P1 negatively regulates P2 via direct physical interaction between an agent executing P1 (or some part of P1) and an agent executing P2 (or some part of P2). For example, if protein A has protein binding activity(P1) that targets protein B and this binding negatively regulates the kinase activity (P2) of protein B then P2 directly negatively regulated by P1." ; rdfs:range xsd:string ; rdfs:subPropertyOf obo:RO_0002022 . obo:RO_0002024 a rdf:Property ; rdfs:label "directly positively regulated by" ; rdfs:comment "Process(P2) is directly postively regulated by process(P1) iff: P1 positively regulates P2 via direct physical interaction between an agent executing P1 (or some part of P1) and an agent executing P2 (or some part of P2). For example, if protein A has protein binding activity(P1) that targets protein B and this binding positively regulates the kinase activity (P2) of protein B then P2 is directly postively regulated by P1." ; rdfs:range xsd:string ; rdfs:subPropertyOf obo:RO_0002022 . obo:RO_0002086 a rdf:Property ; rdfs:label "ends after"@en ; rdfs:comment "X ends_after Y iff: end(Y) before_or_simultaneous_with end(X)"@en ; rdfs:range xsd:string ; rdfs:subPropertyOf obo:RO_0002222 . obo:RO_0002087 a rdf:Property ; rdfs:label "immediately preceded by"@en ; rdfs:comment "X immediately_preceded_by Y iff: end(X) simultaneous_with start(Y)"@en ; rdfs:range xsd:string ; rdfs:subPropertyOf obo:BFO_0000062 . obo:RO_0002090 a rdf:Property ; rdfs:label "immediately precedes"@en ; rdfs:comment "X immediately_precedes_Y iff: end(X) simultaneous_with start(Y)"@en ; rdfs:range xsd:string ; rdfs:subPropertyOf obo:BFO_0000063 . obo:RO_0002131 a rdf:Property ; rdfs:label "overlaps"@en ; rdfs:comment "x overlaps y if and only if there exists some z such that x has part z and z part of y" ; rdfs:range xsd:string ; rdfs:subPropertyOf obo:RO_0002323 . obo:RO_0002163 a rdf:Property ; rdfs:label "spatially disjoint from" ; rdfs:comment "A is spatially_disjoint_from B if and only if they have no parts in common" ; rdfs:range xsd:string ; rdfs:subPropertyOf obo:RO_0002323 . obo:RO_0002180 a rdf:Property ; rdfs:label "has component"@en ; rdfs:comment "w 'has component' p if w 'has part' p and w is such that it can be directly disassembled into into n parts p, p2, p3, ..., pn, where these parts are of similar type." ; rdfs:seeAlso ; rdfs:range xsd:string ; rdfs:subPropertyOf obo:BFO_0000051 . obo:RO_0002200 a rdf:Property ; rdfs:label "has phenotype"@en ; rdfs:comment "A relationship that holds between a biological entity and a phenotype. Here a phenotype is construed broadly as any kind of quality of an organism part, a collection of these qualities, or a change in quality or qualities (e.g. abnormally increased temperature). The subject of this relationship can be an organism (where the organism has the phenotype, i.e. the qualities inhere in parts of this organism), a genomic entity such as a gene or genotype (if modifications of the gene or the genotype causes the phenotype), or a condition such as a disease (such that if the condition inheres in an organism, then the organism has the phenotype)." ; rdfs:range xsd:string ; rdfs:subPropertyOf obo:RO_0016001 . obo:RO_0002211 a rdf:Property ; rdfs:label "regulates"@en ; rdfs:comment "process(P1) regulates process(P2) iff: P1 results in the initiation or termination of P2 OR affects the frequency of its initiation or termination OR affects the magnitude or rate of output of P2." ; rdfs:range xsd:string ; rdfs:subPropertyOf obo:RO_0002411 . obo:RO_0002212 a rdf:Property ; rdfs:label "negatively regulates"@en ; rdfs:comment "Process(P1) negatively regulates process(P2) iff: P1 terminates P2, or P1 descreases the the frequency of initiation of P2 or the magnitude or rate of output of P2." ; rdfs:range xsd:string ; rdfs:subPropertyOf obo:RO_0002305 , obo:RO_0002211 . obo:RO_0002213 a rdf:Property ; rdfs:label "positively regulates"@en ; rdfs:comment "Process(P1) postively regulates process(P2) iff: P1 initiates P2, or P1 increases the the frequency of initiation of P2 or the magnitude or rate of output of P2." ; rdfs:range xsd:string ; rdfs:subPropertyOf obo:RO_0002304 , obo:RO_0002211 . obo:RO_0002216 a rdf:Property ; rdfs:label "capable of part of"@en ; rdfs:comment "c stands in this relationship to p if and only if there exists some p' such that c is capable_of p', and p' is part_of p." ; rdfs:seeAlso ; rdfs:range xsd:string ; rdfs:subPropertyOf obo:RO_0002500 , obo:RO_0002328 . obo:RO_0002219 a rdf:Property ; rdfs:label "surrounded by" ; rdfs:comment "x surrounded_by y if and only if (1) x is adjacent to y and for every region r that is adjacent to x, r overlaps y (2) the shared boundary between x and y occupies the majority of the outermost boundary of x" ; rdfs:range xsd:string ; rdfs:subPropertyOf obo:RO_0002220 . obo:RO_0002220 a rdf:Property ; rdfs:label "adjacent to"@en ; rdfs:comment "x adjacent to y if and only if x and y share a boundary." ; rdfs:range xsd:string ; rdfs:subPropertyOf obo:RO_0002163 . obo:RO_0002222 a rdf:Property ; rdfs:label "temporal relation"@en ; rdfs:comment "A relation that holds between two occurrents. This is a grouping relation that collects together all the Allen relations." ; rdfs:range obo:BFO_0000003 . obo:RO_0002240 a rdf:Property ; rdfs:label "has exposure receptor" ; rdfs:comment "A broad relationship between an exposure event or process and any entity (e.g., an organism, organism population, or an organism part) that interacts with an exposure stimulus during the exposure event." ; rdfs:range xsd:string ; rdfs:subPropertyOf obo:RO_0002244 . obo:RO_0002241 a rdf:Property ; rdfs:label "has exposure stressor" ; rdfs:comment "A broad relationship between an exposure event or process and any agent, stimulus, activity, or event that causes stress or tension on an organism and interacts with an exposure receptor during an exposure event." ; rdfs:range xsd:string ; rdfs:subPropertyOf obo:RO_0002309 . obo:RO_0002242 a rdf:Property ; rdfs:label "has exposure route" ; rdfs:comment "A broad relationship between an exposure event or process and a process by which the exposure stressor comes into contact with the exposure receptor" ; rdfs:range xsd:string ; rdfs:subPropertyOf obo:RO_0002244 . obo:RO_0002243 a rdf:Property ; rdfs:label "has exposure transport path" ; rdfs:comment "A broad relationship between an exposure event or process and the course takes from the source to the target." ; rdfs:range xsd:string ; rdfs:subPropertyOf obo:RO_0002244 . obo:RO_0002244 a rdf:Property ; rdfs:label "related via exposure to" ; rdfs:comment "Any relationship between an exposure event or process and any other entity." ; rdfs:range xsd:string ; rdfs:subPropertyOf obo:RO_0002410 . obo:RO_0002263 a rdf:Property ; rdfs:label "acts upstream of" ; rdfs:comment "c acts upstream of p if and only if c enables some f that is involved in p' and p' occurs chronologically before p, is not part of p, and affects the execution of p. c is a material entity and f, p, p' are processes." ; rdfs:seeAlso ; rdfs:range xsd:string ; rdfs:subPropertyOf obo:RO_0002264 . obo:RO_0002264 a rdf:Property ; rdfs:label "acts upstream of or within" ; rdfs:comment "c acts upstream of or within p if c is enables f, and f is causally upstream of or within p. c is a material entity and p is an process." ; rdfs:seeAlso ; rdfs:range xsd:string ; rdfs:subPropertyOf obo:RO_0002500 . obo:RO_0002302 a rdf:Property ; rdfs:label "is treated by substance" ; rdfs:comment "Inverse of 'is substance that treats'" ; rdfs:range xsd:string ; rdfs:subPropertyOf obo:RO_0002410 . obo:RO_0002304 a rdf:Property ; rdfs:label "causally upstream of, positive effect" ; rdfs:comment "holds between x and y if and only if x is causally upstream of y and the progression of x increases the frequency, rate or extent of y" ; rdfs:range xsd:string ; rdfs:subPropertyOf obo:RO_0004047 , obo:RO_0002411 . obo:RO_0002305 a rdf:Property ; rdfs:label "causally upstream of, negative effect" ; rdfs:comment "holds between x and y if and only if x is causally upstream of y and the progression of x decreases the frequency, rate or extent of y" ; rdfs:range xsd:string ; rdfs:subPropertyOf obo:RO_0004046 , obo:RO_0002411 . obo:RO_0002309 a rdf:Property ; rdfs:label "has exposure stimulus" ; rdfs:comment "A relationship between an exposure event or process and any agent, stimulus, activity, or event that causally effects an organism and interacts with an exposure receptor during an exposure event." ; rdfs:range xsd:string ; rdfs:subPropertyOf obo:RO_0002244 . obo:RO_0002314 a rdf:Property ; rdfs:label "inheres in part of"@en ; rdfs:comment "q inheres in part of w if and only if there exists some p such that q inheres in p and p part of w." ; rdfs:range xsd:string ; rdfs:subPropertyOf obo:RO_0002502 . obo:RO_0002323 a rdf:Property ; rdfs:label "mereotopologically related to"@en ; rdfs:comment "A mereological relationship or a topological relationship" ; rdfs:range . obo:RO_0002326 a rdf:Property ; rdfs:label "contributes to"@en ; rdfs:range xsd:string ; rdfs:subPropertyOf obo:RO_0002329 , obo:RO_0002216 . obo:RO_0002327 a rdf:Property ; rdfs:label "enables"@en ; rdfs:range xsd:string ; rdfs:subPropertyOf obo:RO_0002215 . obo:RO_0002328 a rdf:Property ; rdfs:label "functionally related to"@en ; rdfs:comment "A grouping relationship for any relationship directly involving a function, or that holds because of a function of one of the related entities." ; rdfs:range . obo:RO_0002329 a rdf:Property ; rdfs:label "part of structure that is capable of"@en ; rdfs:comment "this relation holds between c and p when c is part of some c', and c' is capable of p." ; rdfs:range xsd:string ; rdfs:subPropertyOf obo:RO_0002328 . obo:RO_0002331 a rdf:Property ; rdfs:label "involved in"@en ; rdfs:comment "c involved_in p if and only if c enables some process p', and p' is part of p" ; rdfs:seeAlso ; rdfs:range xsd:string ; rdfs:subPropertyOf obo:RO_0002431 , obo:RO_0000056 . obo:RO_0002334 a rdf:Property ; rdfs:label "regulated by"@en ; rdfs:comment "inverse of regulates" ; rdfs:range xsd:string ; rdfs:subPropertyOf obo:RO_0002427 . obo:RO_0002335 a rdf:Property ; rdfs:label "negatively regulated by"@en ; rdfs:comment "inverse of negatively regulates" ; rdfs:range xsd:string ; rdfs:subPropertyOf obo:RO_0002334 . obo:RO_0002336 a rdf:Property ; rdfs:label "positively regulated by"@en ; rdfs:comment "inverse of positively regulates" ; rdfs:range xsd:string ; rdfs:subPropertyOf obo:RO_0002334 . obo:RO_0002404 a rdf:Property ; rdfs:label "causally downstream of"@en ; rdfs:comment "inverse of upstream of" ; rdfs:range xsd:string ; rdfs:subPropertyOf obo:RO_0002427 , obo:BFO_0000062 . obo:RO_0002405 a rdf:Property ; rdfs:label "immediately causally downstream of"@en ; rdfs:range xsd:string ; rdfs:subPropertyOf obo:RO_0002404 , obo:RO_0002087 . obo:RO_0002406 a rdf:Property ; rdfs:label "directly activates"@en ; rdfs:comment "p directly activates q if and only if p is immediately upstream of q and p is the realization of a function to increase the rate or activity of q" ; rdfs:range xsd:string ; rdfs:subPropertyOf obo:RO_0002629 . obo:RO_0002407 a rdf:Property ; rdfs:label "indirectly activates"@en ; rdfs:comment "p indirectly activates q if and only if p is upstream of q and there is a chain of directly activates relationships connecting p and q, where the chain is of length greater than one." ; rdfs:range xsd:string ; rdfs:subPropertyOf obo:RO_0002213 . obo:RO_0002408 a rdf:Property ; rdfs:label "directly inhibits"@en ; rdfs:range xsd:string ; rdfs:subPropertyOf obo:RO_0002630 . obo:RO_0002409 a rdf:Property ; rdfs:label "indirectly inhibits"@en ; rdfs:range xsd:string ; rdfs:subPropertyOf obo:RO_0002212 . obo:RO_0002410 a rdf:Property ; rdfs:label "causally related to"@en ; rdfs:comment "This relation groups causal relations between material entities and causal relations between processes" ; rdfs:range . obo:RO_0002411 a rdf:Property ; rdfs:label "causally upstream of"@en ; rdfs:comment "p is causally upstream of q if and only if p precedes q and p and q are linked in a causal chain" ; rdfs:range xsd:string ; rdfs:subPropertyOf obo:RO_0002418 , obo:BFO_0000063 . obo:RO_0002412 a rdf:Property ; rdfs:label "immediately causally upstream of"@en ; rdfs:comment "p is immediately causally upstream of q iff both (a) p immediately precedes q and (b) p is causally upstream of q. In addition, the output of p must be an input of q." ; rdfs:range xsd:string ; rdfs:subPropertyOf obo:RO_0002411 , obo:RO_0002090 . obo:RO_0002413 a rdf:Property ; rdfs:label "directly provides input for"@en ; rdfs:comment "p1 directly provides input for p2 iff there exists some c such that p1 has_output c and p2 has_input c" ; rdfs:range xsd:string ; rdfs:subPropertyOf obo:RO_0002414 , obo:RO_0002412 . obo:RO_0002414 a rdf:Property ; rdfs:label "transitively provides input for"@en ; rdfs:comment "transitive form of directly_provides_input_for" ; rdfs:range xsd:string ; rdfs:subPropertyOf obo:RO_0002411 . obo:RO_0002416 a rdf:Property ; rdfs:label "logical macro assertion" ; rdfs:comment "An assertion that involves at least one OWL object that is intended to be expanded into one or more logical axioms. The logical expansion can yield axioms expressed using any formal logical system, including, but not limited to OWL2-DL." ; rdfs:seeAlso ; rdfs:range xsd:string . obo:RO_0002418 a rdf:Property ; rdfs:label "causally upstream of or within" ; rdfs:comment "p 'causally upstream or within' q iff (1) the end of p is before the end of q and (2) the execution of p exerts some causal influence over the outputs of q; i.e. if p was abolished or the outputs of p were to be modified, this would necessarily affect q." ; rdfs:range xsd:string ; rdfs:subPropertyOf obo:RO_0002501 . obo:RO_0002421 a rdf:Property ; rdfs:label "logical macro assertion on a property" ; rdfs:comment "A logical macro assertion whose domain is an IRI for a property" ; rdfs:range xsd:string ; rdfs:subPropertyOf obo:RO_0002416 . obo:RO_0002422 a rdf:Property ; rdfs:label "logical macro assertion on an object property" ; rdfs:comment "Used to annotate object properties to describe a logical meta-property or characteristic of the object property." ; rdfs:range xsd:string ; rdfs:subPropertyOf obo:RO_0002421 . obo:RO_0002423 a rdf:Property ; rdfs:label "logical macro assertion on an annotation property"@en ; rdfs:range xsd:string ; rdfs:subPropertyOf obo:RO_0002421 . obo:RO_0002427 a rdf:Property ; rdfs:label "causally downstream of or within" ; rdfs:comment "inverse of causally upstream of or within" ; rdfs:range xsd:string ; rdfs:subPropertyOf obo:RO_0002501 . obo:RO_0002428 a rdf:Property ; rdfs:label "involved in regulation of" ; rdfs:comment "c involved in regulation of p if c is involved in some p' and p' regulates some p" ; rdfs:range xsd:string ; rdfs:subPropertyOf obo:RO_0002431 , obo:RO_0002263 . obo:RO_0002429 a rdf:Property ; rdfs:label "involved in positive regulation of" ; rdfs:comment "c involved in regulation of p if c is involved in some p' and p' positively regulates some p" ; rdfs:range xsd:string ; rdfs:subPropertyOf obo:RO_0002428 . obo:RO_0002430 a rdf:Property ; rdfs:label "involved in negative regulation of" ; rdfs:comment "c involved in regulation of p if c is involved in some p' and p' negatively regulates some p" ; rdfs:range xsd:string ; rdfs:subPropertyOf obo:RO_0002428 . obo:RO_0002431 a rdf:Property ; rdfs:label "involved in or involved in regulation of" ; rdfs:comment "c involved in or regulates p if and only if either (i) c is involved in p or (ii) c is involved in regulation of p" ; rdfs:range xsd:string ; rdfs:subPropertyOf obo:RO_0002328 , obo:RO_0002500 , obo:RO_0002264 . obo:RO_0002434 a rdf:Property ; rdfs:label "interacts with" ; rdfs:comment "A relationship that holds between two entities in which the processes executed by the two entities are causally connected." ; rdfs:seeAlso ; rdfs:range . obo:RO_0002448 a rdf:Property ; rdfs:label "directly regulates activity of" ; rdfs:comment """The entity A, immediately upstream of the entity B, has an activity that regulates an activity performed by B. For example, A and B may be gene products and binding of B by A regulates the kinase activity of B. A and B can be physically interacting but not necessarily. Immediately upstream means there are no intermediate entity between A and B.""" ; rdfs:range xsd:string ; rdfs:subPropertyOf obo:RO_0011002 , obo:RO_0002436 . obo:RO_0002449 a rdf:Property ; rdfs:label "directly negatively regulates activity of" ; rdfs:comment """The entity A, immediately upstream of the entity B, has an activity that negatively regulates an activity performed by B. For example, A and B may be gene products and binding of B by A negatively regulates the kinase activity of B.""" ; rdfs:range xsd:string ; rdfs:subPropertyOf obo:RO_0002448 . obo:RO_0002450 a rdf:Property ; rdfs:label "directly positively regulates activity of" ; rdfs:comment """The entity A, immediately upstream of the entity B, has an activity that positively regulates an activity performed by B. For example, A and B may be gene products and binding of B by A positively regulates the kinase activity of B.""" ; rdfs:range xsd:string ; rdfs:subPropertyOf obo:RO_0002448 . obo:RO_0002473 a rdf:Property ; rdfs:label "composed primarily of" ; rdfs:comment "x composed_primarily_of y if and only if more than half of the mass of x is made from y or units of the same type as y." ; rdfs:range xsd:string ; rdfs:subPropertyOf obo:BFO_0000051 . obo:RO_0002496 a rdf:Property ; rdfs:label "existence starts during or after" ; rdfs:range . obo:RO_0002500 a rdf:Property ; rdfs:label "causal agent in process" ; rdfs:comment "A relationship between a material entity and a process where the material entity has some causal role that influences the process" ; rdfs:range xsd:string ; rdfs:subPropertyOf obo:RO_0002595 . obo:RO_0002501 a rdf:Property ; rdfs:label "causal relation between processes" ; rdfs:comment "p is causally related to q if and only if p or any part of p and q or any part of q are linked by a chain of events where each event pair is one of direct activation or direct inhibition. p may be upstream, downstream, part of or a container of q." ; rdfs:range xsd:string ; rdfs:subPropertyOf obo:RO_0002410 . obo:RO_0002502 a rdf:Property ; rdfs:label "depends on" ; rdfs:range . obo:RO_0002506 a rdf:Property ; rdfs:label "causal relation between entities" ; rdfs:range xsd:string ; rdfs:subPropertyOf obo:RO_0002410 . obo:RO_0002507 a rdf:Property ; rdfs:label "determined by" ; rdfs:comment "s determined by f if and only if s is a type of system, and f is a material entity that is part of s, such that f exerts a strong causal influence on the functioning of s, and the removal of f would cause the collapse of s." ; rdfs:range xsd:string ; rdfs:subPropertyOf obo:RO_0002509 , obo:RO_0002559 , obo:BFO_0000050 . obo:RO_0002508 a rdf:Property ; rdfs:label "determines" ; rdfs:comment "inverse of determined by" ; rdfs:range xsd:string ; rdfs:subPropertyOf obo:RO_0002566 . obo:RO_0002509 a rdf:Property ; rdfs:label "determined by part of" ; rdfs:comment "s 'determined by part of' w if and only if there exists some f such that (1) s 'determined by' f and (2) f part_of w, or f=w." ; rdfs:range xsd:string ; rdfs:subPropertyOf obo:RO_0002506 , obo:RO_0002131 . obo:RO_0002559 a rdf:Property ; rdfs:label "causally influenced by" ; rdfs:range xsd:string ; rdfs:subPropertyOf obo:RO_0002506 . obo:RO_0002566 a rdf:Property ; rdfs:label "causally influences" ; rdfs:comment "The entity or characteristic A is causally upstream of the entity or characteristic B, A having an effect on B. An entity corresponds to any biological type of entity as long as a mass is measurable. A characteristic corresponds to a particular specificity of an entity (e.g., phenotype, shape, size)." ; rdfs:range xsd:string ; rdfs:subPropertyOf obo:RO_0002506 . obo:RO_0002575 a rdf:Property ; rdfs:label "is direct form of" ; rdfs:comment "relation p is the direct form of relation q iff p is a subPropertyOf q, p does not have the Transitive characteristic, q does have the Transitive characteristic, and for all x, y: x q y -> exists z1, z2, ..., zn such that x p z1 ... z2n y" ; rdfs:seeAlso ; rdfs:range xsd:string ; rdfs:subPropertyOf obo:RO_0002422 . obo:RO_0002578 a rdf:Property ; rdfs:label "directly regulates" ; rdfs:comment "Process(P1) directly regulates process(P2) iff: P1 regulates P2 via direct physical interaction between an agent executing P1 (or some part of P1) and an agent executing P2 (or some part of P2). For example, if protein A has protein binding activity(P1) that targets protein B and this binding regulates the kinase activity (P2) of protein B then P1 directly regulates P2." ; rdfs:range xsd:string ; rdfs:subPropertyOf obo:RO_0002412 , obo:RO_0002211 . obo:RO_0002579 a rdf:Property ; rdfs:label "is indirect form of" ; rdfs:comment "relation p is the indirect form of relation q iff p is a subPropertyOf q, and there exists some p' such that p' is the direct form of q, p' o p' -> p, and forall x,y : x q y -> either (1) x p y or (2) x p' y" ; rdfs:seeAlso ; rdfs:range xsd:string ; rdfs:subPropertyOf obo:RO_0002422 . obo:RO_0002584 a rdf:Property ; rdfs:label "has part structure that is capable of" ; rdfs:comment "s 'has part structure that is capable of' p if and only if there exists some part x such that s 'has part' x and x 'capable of' p" ; rdfs:range xsd:string ; rdfs:subPropertyOf obo:RO_0002595 , obo:RO_0002328 . obo:RO_0002595 a rdf:Property ; rdfs:label "causal relation between material entity and a process" ; rdfs:comment "A relationship that holds between a material entity and a process in which causality is involved, with either the material entity or some part of the material entity exerting some influence over the process, or the process influencing some aspect of the material entity." ; rdfs:range xsd:string ; rdfs:subPropertyOf obo:RO_0002410 . obo:RO_0002596 a rdf:Property ; rdfs:label "capable of regulating" ; rdfs:comment "Holds between c and p if and only if c is capable of some activity a, and a regulates p." ; rdfs:range xsd:string ; rdfs:subPropertyOf obo:RO_0002500 . obo:RO_0002599 a rdf:Property ; rdfs:label "capable of inhibiting or preventing pathological process" ; rdfs:comment "Holds between a material entity c and a pathological process p if and only if c is capable of some activity a, where a inhibits p." ; rdfs:range xsd:string ; rdfs:subPropertyOf obo:RO_0002597 . obo:RO_0002600 a rdf:Property ; rdfs:label "capable of upregulating or causing pathological process" ; rdfs:comment "Holds between a material entity c and a pathological process p if and only if c is capable of some activity a, where a negatively regulates p." ; rdfs:range xsd:string ; rdfs:subPropertyOf obo:RO_0002598 . obo:RO_0002609 a rdf:Property ; rdfs:label "obsolete related via dependence to" ; rdfs:comment "A relationship that holds between two entities, where the relationship holds based on the presence or absence of statistical dependence relationship. The entities may be statistical variables, or they may be other kinds of entities such as diseases, chemical entities or processes." ; rdfs:range . obo:RO_0002629 a rdf:Property ; rdfs:label "directly positively regulates" ; rdfs:comment "Process(P1) directly postively regulates process(P2) iff: P1 positively regulates P2 via direct physical interaction between an agent executing P1 (or some part of P1) and an agent executing P2 (or some part of P2). For example, if protein A has protein binding activity(P1) that targets protein B and this binding positively regulates the kinase activity (P2) of protein B then P1 directly positively regulates P2." ; rdfs:range xsd:string ; rdfs:subPropertyOf obo:RO_0002578 , obo:RO_0002213 . obo:RO_0002630 a rdf:Property ; rdfs:label "directly negatively regulates" ; rdfs:comment "Process(P1) directly negatively regulates process(P2) iff: P1 negatively regulates P2 via direct physical interaction between an agent executing P1 (or some part of P1) and an agent executing P2 (or some part of P2). For example, if protein A has protein binding activity(P1) that targets protein B and this binding negatively regulates the kinase activity (P2) of protein B then P1 directly negatively regulates P2." ; rdfs:range xsd:string ; rdfs:subPropertyOf obo:RO_0002578 , obo:RO_0002212 . obo:RO_0003002 a rdf:Property ; rdfs:label "represses expression of" ; rdfs:comment "Holds between entity A (a transcription factor) and a nucleic acid B if and only if A down-regulates the expression of B. The nucleic acid can be a gene or an mRNA." ; rdfs:range xsd:string ; rdfs:subPropertyOf obo:RO_0002449 . obo:RO_0003003 a rdf:Property ; rdfs:label "increases expression of" ; rdfs:comment "Holds between entity A (a transcription factor) and nucleic acid B if and only if A up-regulates the expression of B. The nucleic acid can be a gene or mRNA." ; rdfs:range xsd:string ; rdfs:subPropertyOf obo:RO_0002450 . obo:RO_0003302 a rdf:Property ; rdfs:label "causes or contributes to condition"@en ; rdfs:comment "A relationship between an entity (e.g. a genotype, genetic variation, chemical, or environmental exposure) and a condition (a phenotype or disease), where the entity has some causal or contributing role that influences the condition." ; rdfs:range xsd:string ; rdfs:subPropertyOf obo:RO_0002410 . obo:RO_0003303 a rdf:Property ; rdfs:label "causes condition"@en ; rdfs:comment "A relationship between an entity (e.g. a genotype, genetic variation, chemical, or environmental exposure) and a condition (a phenotype or disease), where the entity has some causal role for the condition." ; rdfs:range xsd:string ; rdfs:subPropertyOf obo:RO_0003302 . obo:RO_0003304 a rdf:Property ; rdfs:label "contributes to condition"@en ; rdfs:comment "A relationship between an entity (e.g. a genotype, genetic variation, chemical, or environmental exposure) and a condition (a phenotype or disease), where the entity has some contributing role that influences the condition." ; rdfs:range xsd:string ; rdfs:subPropertyOf obo:RO_0003302 . obo:RO_0003305 a rdf:Property ; rdfs:label "contributes to severity of condition"@en ; rdfs:comment "A relationship between an entity (e.g. a genotype, genetic variation, chemical, or environmental exposure) and a condition (a phenotype or disease), where the entity influences the severity with which a condition manifests in an individual." ; rdfs:range xsd:string ; rdfs:subPropertyOf obo:RO_0003304 . obo:RO_0003306 a rdf:Property ; rdfs:label "contributes to frequency of condition"@en ; rdfs:comment "A relationship between an entity (e.g. a genotype, genetic variation, chemical, or environmental exposure) and a condition (a phenotype or disease), where the entity influences the frequency of the condition in a population." ; rdfs:range xsd:string ; rdfs:subPropertyOf obo:RO_0003304 . obo:RO_0003307 a rdf:Property ; rdfs:label "ameliorates condition"@en ; rdfs:comment "A relationship between an entity (e.g. a genotype, genetic variation, chemical, or environmental exposure) and a condition (a phenotype or disease), where the presence of the entity reduces or eliminates some or all aspects of the condition." ; rdfs:range xsd:string ; rdfs:subPropertyOf obo:RO_0003305 . obo:RO_0003309 a rdf:Property ; rdfs:label "exacerbates condition"@en ; rdfs:comment "A relationship between an entity (e.g. a chemical, environmental exposure, or some form of genetic variation) and a condition (a phenotype or disease), where the presence of the entity worsens some or all aspects of the condition." ; rdfs:range xsd:string ; rdfs:subPropertyOf obo:RO_0003305 . obo:RO_0003310 a rdf:Property ; rdfs:label "condition ameliorated by"@en ; rdfs:comment "A relationship between a condition (a phenotype or disease) and an entity (e.g. a chemical, environmental exposure, or some form of genetic variation) where some or all aspects of the condition are reduced or eliminated by the presence of the entity." ; rdfs:range xsd:string ; rdfs:subPropertyOf obo:RO_0002410 . obo:RO_0003311 a rdf:Property ; rdfs:label "condition exacerbated by"@en ; rdfs:comment "A relationship between a condition (a phenotype or disease) and an entity (e.g. a chemical, environmental exposure, or some form of genetic variation) where some or all aspects of the condition are worsened by the presence of the entity." ; rdfs:range xsd:string ; rdfs:subPropertyOf obo:RO_0002410 . obo:RO_0004000 a rdf:Property ; rdfs:label "condition has genetic basis in" ; rdfs:range xsd:string ; rdfs:subPropertyOf obo:RO_0002410 . obo:RO_0004001 a rdf:Property ; rdfs:label "has material basis in gain of function germline mutation in" ; rdfs:seeAlso , ; rdfs:range xsd:string ; rdfs:subPropertyOf obo:RO_0004000 . obo:RO_0004002 a rdf:Property ; rdfs:label "has material basis in loss of function germline mutation in" ; rdfs:range xsd:string ; rdfs:subPropertyOf obo:RO_0004000 . obo:RO_0004003 a rdf:Property ; rdfs:label "has material basis in germline mutation in" ; rdfs:seeAlso ; rdfs:range xsd:string ; rdfs:subPropertyOf obo:RO_0004000 . obo:RO_0004004 a rdf:Property ; rdfs:label "has material basis in somatic mutation in" ; rdfs:seeAlso ; rdfs:range xsd:string ; rdfs:subPropertyOf obo:RO_0004000 . obo:RO_0004005 a rdf:Property ; rdfs:label "has major susceptibility factor" ; rdfs:range xsd:string ; rdfs:subPropertyOf obo:RO_0004000 . obo:RO_0004006 a rdf:Property ; rdfs:label "has partial material basis in germline mutation in" ; rdfs:range xsd:string ; rdfs:subPropertyOf obo:RO_0004000 . obo:RO_0004010 a rdf:Property ; rdfs:label "is genetic basis for condition" ; rdfs:range xsd:string ; rdfs:subPropertyOf obo:RO_0004018 . obo:RO_0004011 a rdf:Property ; rdfs:label "is causal gain of function germline mutation of in" ; rdfs:comment "Relates a gene to condition, such that a mutation in this gene in a germ cell provides a new function of the corresponding product and that is sufficient to produce the condition and that can be passed on to offspring[modified from orphanet]." ; rdfs:seeAlso ; rdfs:range xsd:string ; rdfs:subPropertyOf obo:RO_0004010 . obo:RO_0004012 a rdf:Property ; rdfs:label "is causal loss of function germline mutation of in" ; rdfs:comment "Relates a gene to condition, such that a mutation in this gene in a germ cell impairs the function of the corresponding product and that is sufficient to produce the condition and that can be passed on to offspring[modified from orphanet]." ; rdfs:seeAlso ; rdfs:range xsd:string ; rdfs:subPropertyOf obo:RO_0004010 . obo:RO_0004013 a rdf:Property ; rdfs:label "is causal germline mutation in" ; rdfs:comment "Relates a gene to condition, such that a mutation in this gene is sufficient to produce the condition and that can be passed on to offspring[modified from orphanet]." ; rdfs:seeAlso ; rdfs:range xsd:string ; rdfs:subPropertyOf obo:RO_0004010 , obo:RO_0003303 . obo:RO_0004014 a rdf:Property ; rdfs:label "is causal somatic mutation in" ; rdfs:comment "Relates a gene to condition, such that a mutation in this gene is sufficient to produce the condition but that cannot be passed on to offspring[modified from orphanet]." ; rdfs:seeAlso ; rdfs:range xsd:string ; rdfs:subPropertyOf obo:RO_0004010 , obo:RO_0003303 . obo:RO_0004015 a rdf:Property ; rdfs:label "is causal susceptibility factor for" ; rdfs:comment "Relates a gene to condition, such that a mutation in this gene predisposes to the development of a condition and that is necessary but not sufficient to develop the condition[modified from orphanet]." ; rdfs:seeAlso ; rdfs:range xsd:string ; rdfs:subPropertyOf obo:RO_0004010 . obo:RO_0004016 a rdf:Property ; rdfs:label "is causal germline mutation partially giving rise to" ; rdfs:comment "Relates a gene to condition, such that a mutation in this gene partially contributes to the presentation of this condition[modified from orphanet]." ; rdfs:seeAlso ; rdfs:range xsd:string ; rdfs:subPropertyOf obo:RO_0004010 , obo:RO_0003304 . obo:RO_0004017 a rdf:Property ; rdfs:label "realizable has basis in" ; rdfs:range xsd:string ; rdfs:subPropertyOf obo:RO_0002410 . obo:RO_0004018 a rdf:Property ; rdfs:label "is basis for realizable" ; rdfs:range xsd:string ; rdfs:subPropertyOf obo:RO_0002410 . obo:RO_0004019 a rdf:Property ; rdfs:label "disease has basis in" ; rdfs:range xsd:string ; rdfs:subPropertyOf obo:RO_0004023 , obo:RO_0004017 . obo:RO_0004020 a rdf:Property ; rdfs:label "disease has basis in dysfunction of" ; rdfs:comment "A relation that holds between the disease and a material entity where the physical basis of the disease is a disorder of that material entity that affects its function." ; rdfs:range xsd:string ; rdfs:subPropertyOf obo:RO_0004019 . obo:RO_0004021 a rdf:Property ; rdfs:label "disease has basis in disruption of" ; rdfs:comment "A relation that holds between the disease and a process where the physical basis of the disease disrupts execution of a key biological process." ; rdfs:range xsd:string ; rdfs:subPropertyOf obo:RO_0004019 . obo:RO_0004022 a rdf:Property ; rdfs:label "disease has basis in feature" ; rdfs:comment "A relation that holds between the disease and a feature (a phenotype or other disease) where the physical basis of the disease is the feature." ; rdfs:range xsd:string ; rdfs:subPropertyOf obo:RO_0004019 , obo:RO_0002200 . obo:RO_0004023 a rdf:Property ; rdfs:label "causal relationship with disease as subject" ; rdfs:range xsd:string ; rdfs:subPropertyOf obo:RO_0040035 , obo:RO_0002410 . obo:RO_0004024 a rdf:Property ; rdfs:label "disease causes disruption of" ; rdfs:comment "A relationship between a disease and a process where the disease process disrupts the execution of the process." ; rdfs:range xsd:string ; rdfs:subPropertyOf obo:RO_0004023 . obo:RO_0004025 a rdf:Property ; rdfs:label "disease causes dysfunction of" ; rdfs:range xsd:string ; rdfs:subPropertyOf obo:RO_0004023 . obo:RO_0004028 a rdf:Property ; rdfs:label "realized in response to stimulus" ; rdfs:comment "A relationship between a realizable entity R (e.g. function or disposition) and a material entity M where R is realized in response to a process that has an input stimulus of M." ; rdfs:range xsd:string ; rdfs:subPropertyOf obo:RO_0002410 . obo:RO_0004030 a rdf:Property ; rdfs:label "disease arises from alteration in structure" ; rdfs:comment "A relationship between a disease and an anatomical structure where the material basis of the disease is some pathological change in the structure. Anatomical structure includes cellular and sub-cellular entities, such as chromosome and organelles." ; rdfs:range xsd:string ; rdfs:subPropertyOf obo:RO_0004019 . obo:RO_0004032 a rdf:Property ; rdfs:label "acts upstream of or within, positive effect" ; rdfs:seeAlso ; rdfs:range xsd:string ; rdfs:subPropertyOf obo:RO_0002264 . obo:RO_0004033 a rdf:Property ; rdfs:label "acts upstream of or within, negative effect" ; rdfs:range xsd:string ; rdfs:subPropertyOf obo:RO_0002264 . obo:RO_0004034 a rdf:Property ; rdfs:label "acts upstream of, positive effect" ; rdfs:comment "c 'acts upstream of, positive effect' p if c is enables f, and f is causally upstream of p, and the direction of f is positive" ; rdfs:seeAlso ; rdfs:range xsd:string ; rdfs:subPropertyOf obo:RO_0004032 , obo:RO_0002263 . obo:RO_0004035 a rdf:Property ; rdfs:label "acts upstream of, negative effect" ; rdfs:comment "c 'acts upstream of, negative effect' p if c is enables f, and f is causally upstream of p, and the direction of f is negative" ; rdfs:seeAlso ; rdfs:range xsd:string ; rdfs:subPropertyOf obo:RO_0004033 , obo:RO_0002263 . obo:RO_0004046 a rdf:Property ; rdfs:label "causally upstream of or within, negative effect" ; rdfs:range xsd:string ; rdfs:subPropertyOf obo:RO_0002418 . obo:RO_0004047 a rdf:Property ; rdfs:label "causally upstream of or within, positive effect" ; rdfs:range xsd:string ; rdfs:subPropertyOf obo:RO_0002418 . obo:RO_0004048 a rdf:Property ; rdfs:label "is directional form of" ; rdfs:comment "Used to annotate object properties representing a causal relationship where the value indicates a direction. Should be \"+\", \"-\" or \"0\"" ; rdfs:range xsd:string ; rdfs:subPropertyOf obo:RO_0002422 . obo:RO_0004049 a rdf:Property ; rdfs:label "is positive form of" ; rdfs:range xsd:string ; rdfs:subPropertyOf obo:RO_0004048 . obo:RO_0004050 a rdf:Property ; rdfs:label "is negative form of" ; rdfs:range xsd:string ; rdfs:subPropertyOf obo:RO_0004048 . obo:RO_0009501 a rdf:Property ; rdfs:label "realized in response to"@en ; rdfs:comment "r 'realized in response to' s iff, r is a realizable (e.g. a plant trait such as responsivity to drought), s is an environmental stimulus (a process), and s directly causes the realization of r." ; rdfs:seeAlso ; rdfs:range xsd:string ; rdfs:subPropertyOf obo:RO_0002410 . obo:RO_0011002 a rdf:Property ; rdfs:label "regulates activity of" ; rdfs:comment "The entity A has an activity that regulates an activity of the entity B. For example, A and B are gene products where the catalytic activity of A regulates the kinase activity of B." ; rdfs:range xsd:string ; rdfs:subPropertyOf obo:RO_0002566 . obo:RO_0011003 a rdf:Property ; rdfs:label "regulates quantity of" ; rdfs:comment "The entity A has an activity that regulates the quantity or abundance or concentration of the entity B." ; rdfs:range xsd:string ; rdfs:subPropertyOf obo:RO_0002566 . obo:RO_0011004 a rdf:Property ; rdfs:label "indirectly regulates activity of"@en ; rdfs:comment "The entity A is not immediately upstream of the entity B but A has an activity that regulates an activity performed by B." ; rdfs:range xsd:string ; rdfs:subPropertyOf obo:RO_0011002 . obo:RO_0011007 a rdf:Property ; rdfs:label "decreases by repression quantity of" ; rdfs:comment """The entity A has an activity that down-regulates by repression the quantity of B. The down-regulation is due to A having an effect on an intermediate entity (typically a DNA or mRNA element) which can produce B. For example, protein A (transcription factor) indirectly decreases by repression the quantity of protein B (gene product) if and only if A negatively regulates the process of transcription or translation of a nucleic acid element that produces B.""" ; rdfs:range xsd:string ; rdfs:subPropertyOf obo:RO_0011023 . obo:RO_0011008 a rdf:Property ; rdfs:label "increases by expression quantity of" ; rdfs:comment """The entity A has an activity that up-regulates by expression the quantity of B. The up-regulation is due to A having an effect on an intermediate entity (typically a DNA or mRNA element) which can produce B. For example, protein A (transcription factor) indirectly increases by expression the quantity of protein B (gene product) if and only if A positively regulates the process of transcription or translation of a nucleic acid element that produces B.""" ; rdfs:range xsd:string ; rdfs:subPropertyOf obo:RO_0011024 . obo:RO_0011009 a rdf:Property ; rdfs:label "directly positively regulates quantity of" ; rdfs:comment "The entity A has an activity that directly positively regulates the quantity of B." ; rdfs:range xsd:string ; rdfs:subPropertyOf obo:RO_0011021 . obo:RO_0011010 a rdf:Property ; rdfs:label "directly negatively regulates quantity of" ; rdfs:comment "The entity A has an activity that directly negatively regulates the quantity of B." ; rdfs:range xsd:string ; rdfs:subPropertyOf obo:RO_0011021 . obo:RO_0011013 a rdf:Property ; rdfs:label "indirectly positively regulates activity of" ; rdfs:comment "The entity A is not immediately upstream of the entity B and has an activity that up-regulates an activity performed by B." ; rdfs:range xsd:string ; rdfs:subPropertyOf obo:RO_0011004 . obo:RO_0011014 a rdf:Property ; rdfs:label "destabilizes quantity of" ; rdfs:comment "An entity A directly interacts with B and A has an activity that decreases the amount of an entity B by degradating it." ; rdfs:range xsd:string ; rdfs:subPropertyOf obo:RO_0011010 . obo:RO_0011015 a rdf:Property ; rdfs:label "stabilizes quantity of" ; rdfs:comment "An entity A physically interacts with B and A has an activity that increases the amount of an entity B by stabilizing it." ; rdfs:range xsd:string ; rdfs:subPropertyOf obo:RO_0011009 . obo:RO_0011016 a rdf:Property ; rdfs:label "indirectly negatively regulates activity of" ; rdfs:comment "The entity A is not immediately upstream of the entity B and has an activity that down-regulates an activity performed by B." ; rdfs:range xsd:string ; rdfs:subPropertyOf obo:RO_0011004 . obo:RO_0011021 a rdf:Property ; rdfs:label "directly regulates quantity of" ; rdfs:comment "The entity A, immediately upstream of B, has an activity that directly regulates the quantity of B." ; rdfs:range xsd:string ; rdfs:subPropertyOf obo:RO_0011003 . obo:RO_0011022 a rdf:Property ; rdfs:label "indirectly regulates quantity of" ; rdfs:comment "The entity A is not immediately upstream of the entity B, but A has an activity that regulates the quantity or abundance or concentration of B." ; rdfs:range xsd:string ; rdfs:subPropertyOf obo:RO_0011003 . obo:RO_0011023 a rdf:Property ; rdfs:label "indirectly negatively regulates quantity of" ; rdfs:comment "The entity A does not physically interact with the entity B, and A has an activity that down-regulates the quantity or abundance or concentration of B." ; rdfs:range xsd:string ; rdfs:subPropertyOf obo:RO_0011022 . obo:RO_0011024 a rdf:Property ; rdfs:label "indirectly positively regulates quantity of" ; rdfs:comment "The entity A does not physically interact with the entity B, and A has an activity that up-regulates the quantity or abundance or concentration of B." ; rdfs:range xsd:string ; rdfs:subPropertyOf obo:RO_0011022 . obo:RO_0014001 a rdf:Property ; rdfs:label "disease has infectious agent" ; rdfs:comment "A relationship between a disease and an infectious agent where the material basis of the disease is an infection with some infectious agent." ; rdfs:range xsd:string ; rdfs:subPropertyOf obo:RO_0004019 . obo:RO_0016001 a rdf:Property ; rdfs:label "has phenotype or disease" ; rdfs:seeAlso ; rdfs:range . obo:RO_0016004 a rdf:Property ; rdfs:label "has exposure medium" ; rdfs:comment "X has exposure medium Y if X is an exposure event (process), Y is a material entity, and the stimulus for X is transmitted or carried in Y." ; rdfs:range xsd:string ; rdfs:subPropertyOf obo:RO_0002244 . obo:RO_0019000 a rdf:Property ; rdfs:label "regulates characteristic" ; rdfs:comment "A relationship that holds between a process and a characteristic in which process (P) regulates characteristic (C) iff: P results in the existence of C OR affects the intensity or magnitude of C." ; rdfs:range xsd:string ; rdfs:subPropertyOf obo:RO_0002410 . obo:RO_0019001 a rdf:Property ; rdfs:label "positively regulates characteristic" ; rdfs:comment "A relationship that holds between a process and a characteristic in which process (P) positively regulates characteristic (C) iff: P results in an increase in the intensity or magnitude of C." ; rdfs:range xsd:string ; rdfs:subPropertyOf obo:RO_0019000 . obo:RO_0019002 a rdf:Property ; rdfs:label "negatively regulates characteristic" ; rdfs:comment "A relationship that holds between a process and a characteristic in which process (P) negatively regulates characteristic (C) iff: P results in a decrease in the intensity or magnitude of C." ; rdfs:range xsd:string ; rdfs:subPropertyOf obo:RO_0019000 . obo:RO_0019501 a rdf:Property ; rdfs:label "confers susceptibility to condition" ; rdfs:comment "Relates a gene to condition, such that a variation in this gene predisposes to the development of a condition." ; rdfs:range xsd:string ; rdfs:subPropertyOf obo:RO_0003304 . obo:RO_0040035 a rdf:Property ; rdfs:label "disease relationship" ; rdfs:comment "This relation groups relations between diseases and any other kind of entity." ; rdfs:range . obo:RO_0040042 a rdf:Property ; rdfs:label "is homeomorphic for" ; rdfs:comment "R is homemorphic for C iff (1) there exists some x,y such that x R y, and x and y instantiate C and (2) for all x, if x is an instance of C, and there exists some y some such that x R y, then it follows that y is an instance of C." ; rdfs:seeAlso ; rdfs:range xsd:string ; rdfs:subPropertyOf obo:RO_0002422 . obo:UBPROP_0000001 a rdf:Property ; rdfs:label "external_definition" ; rdfs:comment "An alternate textual definition for a class taken unmodified from an external source. This definition may have been used to derive a generalized definition for the new class." ; rdfs:range xsd:string . obo:UBPROP_0000002 a rdf:Property ; rdfs:label "axiom_lost_from_external_ontology" ; rdfs:comment "A textual description of an axiom loss in this ontology compared to an external ontology." ; rdfs:range xsd:string . obo:UBPROP_0000003 a rdf:Property ; rdfs:label "homology_notes" ; rdfs:comment "Notes on the homology status of this class." ; rdfs:range xsd:string . obo:UBPROP_0000006 a rdf:Property ; rdfs:label "implements_design_pattern" ; rdfs:range xsd:string . obo:UBPROP_0000007 a rdf:Property ; rdfs:label "has_relational_adjective" ; rdfs:range xsd:string . obo:UBPROP_0000008 a rdf:Property ; rdfs:label "taxon_notes" ; rdfs:comment "Notes on the how instances of this class vary across species." ; rdfs:range xsd:string . obo:UBPROP_0000011 a rdf:Property ; rdfs:label "development_notes" ; rdfs:comment "Notes on the ontogenic development of instances of this class." ; rdfs:range xsd:string . obo:UBPROP_0000012 a rdf:Property ; rdfs:label "external_ontology_notes" ; rdfs:comment "Notes on how similar or equivalent classes are represented in other ontologies." ; rdfs:range xsd:string . obo:UBPROP_0000202 a rdf:Property ; rdfs:label "fma_set_term" ; rdfs:range xsd:string . obo:VO_0003099 a rdf:Property ; rdfs:label "trade name" ; rdfs:comment "An annotation property that represents the trade name of a product." ; rdfs:range xsd:string . obo:VO_0003158 a rdf:Property ; rdfs:label "vaccine proper name" ; rdfs:comment "An annotation property that represents the proper name of a vaccine, which is defined in an official way such as one defined by FDA." ; rdfs:range xsd:string . obo:VO_0003159 a rdf:Property ; rdfs:label "manufacturer" ; rdfs:comment "An annotation property that represents the manufacturer of a product such as vaccine" ; rdfs:range xsd:string . obo:VO_0005328 a rdf:Property ; rdfs:label "VAC adjuvant ID"@en ; rdfs:comment "An identifier assigned by the Vaccine Adjuvant Compendium (VAC: https://vac.niaid.nih.gov/)" ; rdfs:range xsd:string . a rdf:Property ; rdfs:label "Unique Apollo Label"@en ; rdfs:comment "This annotation property gives the unique label of all Apollo_SV entities that are refered to in the schema. The UAL is the denotator for the Apollo_SV class in the schema. There can at all times only be ONE value of UAL for each class." ; rdfs:range xsd:string . a rdf:Property ; rdfs:label "has_rank" ; rdfs:comment "A metadata relation between a class and its taxonomic rank (eg species, family)" ; rdfs:range xsd:string . a rdf:Property ; rdfs:range . a rdf:Property ; rdfs:label "has_proper_part" ; rdfs:range . a rdf:Property ; rdfs:label "ontology IUI"@en ; rdfs:range xsd:string . a rdf:Property ; rdfs:label "ontology version IUI"@en ; rdfs:range xsd:string . a rdf:Property ; rdfs:label "depicted by" ; rdfs:range xsd:string . obo:CIDO_0000031 a rdfs:Class ; rdfs:label "FDA EUA-authorized organization"@en ; rdfs:comment "An organization that is authorized by US FDA according to a FDA Emergency Use Authorization (EUA)." ; rdfs:subClassOf obo:OBI_0000245 . obo:CIDO_0000023 a obo:CIDO_0000031 ; rdfs:label "Yale New Haven Hospital"@en . obo:OBI_0000639 a rdfs:Class ; rdfs:label "material separation objective" ; rdfs:comment "is an objective to transform a material entity into spatially separated components." ; rdfs:subClassOf obo:OBI_0000456 . obo:OBI_0000678 a obo:OBI_0000639 ; rdfs:label "portioning objective" ; rdfs:comment "A material separation objective aiming to separate material into multiple portions, each of which contains a similar composition of the input material." . obo:OBI_0000681 a obo:OBI_0000639 ; rdfs:label "separation into different composition objective" ; rdfs:comment "A material separation objective aiming to separate a material entity that has parts of different types, and end with at least one output that is a material with parts of fewer types (modulo impurities)." . obo:VO_0000299 a rdfs:Class ; rdfs:label "company" ; rdfs:comment "A legal organization that represents an association of people with a specific objective." ; rdfs:subClassOf obo:OBI_0000245 . obo:VO_0000204 a obo:VO_0000299 ; rdfs:label "Intervet" . obo:VO_0000690 a obo:VO_0000299 ; rdfs:label "GlaxoSmithKline plc"@en ; rdfs:comment "A British multinational pharmaceutical company headquartered in Brentford, England" . obo:VO_0000701 a obo:VO_0000299 ; rdfs:label "Wyeth Pharmaceuticals Inc" . obo:VO_0000841 a obo:VO_0000299 ; rdfs:label "Pfizer Animal Health" . obo:VO_0001119 a obo:VO_0000299 ; rdfs:label "Merial, Inc" . obo:VO_0001529 a obo:VO_0000299 ; rdfs:label "VacciCel, Inc." ; rdfs:comment """Vaccicel, Inc. has a location in Belton, TX. Active officers include Andre Menchu, Andres Menchu, Kathryn M Baker, Katheryn Becker and Andres Menches. Vaccicel, Inc. filed as a Domestic For-Profit Corporation on Tuesday, August 22, 1995 in the state of Texas and is currently active. Andres Menchu serves as the registered agent for this organization.The company's line of business includes Mfg Research & Development Veterinary Bacterial Vaccines. (http://www.corporationwiki.com/Texas/Belton/vaccicel-inc/34296230.aspx)""" . obo:VO_0003153 a obo:VO_0000299 ; rdfs:label "Dynavax Technologies Corporation"@en ; rdfs:comment "A company trhat is located at Berkeley, CA, USA. Its website is: http://www.dynavax.com." . obo:VO_0004932 a obo:VO_0000299 ; rdfs:label "Janssen Pharmaceutica"@en ; rdfs:comment "A pharmaceutical company that was founded in 1953 by Paul Janssen, is headquartered in Beerse, Belgium, and owned by Johnson & Johnson." . obo:VO_0004947 a obo:VO_0000299 ; rdfs:label "Pfizer Inc."@en ; rdfs:comment "An American multinational pharmaceutical corporation headquartered in New York City."@zh . obo:VO_0004958 a obo:VO_0000299 ; rdfs:label "Vaxxinity"@en . obo:VO_0004969 a obo:VO_0000299 ; rdfs:label "Symvivo"@en . obo:VO_0004970 a obo:VO_0000299 ; rdfs:label "Chulalongkorn University"@en . obo:VO_0004978 a obo:VO_0000299 ; rdfs:label "Medigen, Inc."@en . obo:VO_0004982 a obo:VO_0000299 ; rdfs:label "Clover Biopharmaceuticals, Inc."@en . obo:VO_0004997 a obo:VO_0000299 ; rdfs:label "Cellid Co., Ltd."@en . obo:VO_0004998 a obo:VO_0000299 ; rdfs:label "University Medical Center Groningen"@en . obo:UO_0000002 a rdfs:Class ; rdfs:label "mass unit" ; rdfs:comment "A unit which is a standard measure of the amount of matter/energy of a physical object." ; rdfs:subClassOf obo:IAO_0000003 . obo:UO_0000022 a obo:UO_0000002 ; rdfs:label "milligram" ; rdfs:comment "A mass unit which is equal to one thousandth of a gram or 10^[-3] g." . obo:IAO_0000225 a rdfs:Class ; rdfs:label "obsolescence reason specification"@en ; rdfs:comment "The reason for which a term has been deprecated. The allowed values come from an enumerated list of predefined terms. See the specification of these instances for more detailed definitions of each enumerated value."@en ; rdfs:subClassOf obo:IAO_0000102 . obo:IAO_0000103 a obo:IAO_0000225 ; rdfs:label "failed exploratory term"@en ; rdfs:comment "The term was used in an attempt to structure part of the ontology but in retrospect failed to do a good job"@en . obo:IAO_0000226 a obo:IAO_0000225 ; rdfs:label "placeholder removed"@en . obo:IAO_0000227 a obo:IAO_0000225 ; rdfs:label "terms merged"@en . obo:IAO_0000228 a obo:IAO_0000225 ; rdfs:label "term imported"@en . obo:IAO_0000229 a obo:IAO_0000225 ; rdfs:label "term split"@en . obo:IAO_0000078 a rdfs:Class ; rdfs:label "curation status specification"@en ; rdfs:comment "The curation status of the term. The allowed values come from an enumerated list of predefined terms. See the specification of these instances for more detailed definitions of each enumerated value."@en ; rdfs:subClassOf obo:IAO_0000027 , obo:IAO_0000102 . obo:IAO_0000002 a obo:IAO_0000078 ; rdfs:label "example to be eventually removed"@en . obo:IAO_0000120 a obo:IAO_0000078 ; rdfs:label "metadata complete"@en ; rdfs:comment "Class has all its metadata, but is either not guaranteed to be in its final location in the asserted IS_A hierarchy or refers to another class that is not complete."@en . obo:IAO_0000121 a obo:IAO_0000078 ; rdfs:label "organizational term"@en ; rdfs:comment "term created to ease viewing/sort terms for development purpose, and will not be included in a release"@en . obo:IAO_0000122 a obo:IAO_0000078 ; rdfs:label "ready for release"@en ; rdfs:comment "Class has undergone final review, is ready for use, and will be included in the next release. Any class lacking \"ready_for_release\" should be considered likely to change place in hierarchy, have its definition refined, or be obsoleted in the next release. Those classes deemed \"ready_for_release\" will also derived from a chain of ancestor classes that are also \"ready_for_release.\""@en . obo:IAO_0000123 a obo:IAO_0000078 ; rdfs:label "metadata incomplete"@en ; rdfs:comment "Class is being worked on; however, the metadata (including definition) are not complete or sufficiently clear to the branch editors."@en . obo:IAO_0000124 a obo:IAO_0000078 ; rdfs:label "uncurated"@en ; rdfs:comment "Nothing done yet beyond assigning a unique class ID and proposing a preferred term."@en . obo:IAO_0000125 a obo:IAO_0000078 ; rdfs:label "pending final vetting"@en ; rdfs:comment "All definitions, placement in the asserted IS_A hierarchy and required minimal metadata are complete. The class is awaiting a final review by someone other than the term editor."@en . obo:IAO_0000423 a obo:IAO_0000078 ; rdfs:label "to be replaced with external ontology term"@en ; rdfs:comment "Terms with this status should eventually replaced with a term from another ontology."@en . obo:IAO_0000428 a obo:IAO_0000078 ; rdfs:label "requires discussion"@en ; rdfs:comment "A term that is metadata complete, has been reviewed, and problems have been identified that require discussion before release. Such a term requires editor note(s) to identify the outstanding issues."@en .