PREFIX obo: <http://purl.obolibrary.org/obo/>
PREFIX rdf: <http://www.w3.org/1999/02/22-rdf-syntax-ns#>
PREFIX rdfs: <http://www.w3.org/2000/01/rdf-schema#>
PREFIX xsd: <http://www.w3.org/2001/XMLSchema#>

obo:YPO_0000141 a rdfs:Class .

obo:APO_0000102 a rdfs:Class ;
  rdfs:label "respiratory metabolism" ;
  rdfs:comment "Growth with energy derived from respiration; growth on a non-fermentable carbon source. Examples of non-fermentable carbon sources include glycerol, ethanol, and lactate." ;
  rdfs:subClassOf obo:APO_0000098 .

obo:APO_0000037 a rdfs:Class ;
  rdfs:label "pheromone sensitivity" ;
  rdfs:comment "Sensitivity to mating pheromones produced by cells of the opposite mating type." ;
  rdfs:subClassOf obo:APO_0000032 .

obo:APO_0000290 a rdfs:Class ;
  rdfs:label "allergy induction" ;
  rdfs:comment "OBSOLETE: The induction of an allergic response in the host organism." .

obo:YPO_0000204 a rdfs:Class .

obo:YPO_0000086 a rdfs:Class .

obo:YPO_0000192 a rdfs:Class .

obo:YPO_0000104 a rdfs:Class .

obo:YPO_0000124 a rdfs:Class .

obo:YPO_0000173 a rdfs:Class .

obo:APO_0000021 a rdfs:Class ;
  rdfs:label "competitive growth" ;
  rdfs:comment "Quantitative data on survival of a mutant strain, obtained in large scale experiments where mutants are grown together with wild type or other mutants for many generations." ;
  rdfs:subClassOf obo:APO_0000114 .

obo:APO_0000194 a rdfs:Class ;
  rdfs:label "ionizing radiation resistance" ;
  rdfs:comment "The level of resistance to ionizing radiation." ;
  rdfs:subClassOf obo:APO_0000084 .

obo:APO_0000225 a rdfs:Class ;
  rdfs:label "mitotic recombination" ;
  rdfs:comment "Measures of the rate of recombination or total recombination observed during the mitotic cell cycle." ;
  rdfs:subClassOf obo:APO_0000072 , obo:APO_0000143 .

obo:YPO_0000076 a rdfs:Class .

obo:APO_0000129 a rdfs:Class ;
  rdfs:label "protein transport" ;
  rdfs:comment "Delivery of proteins to specific locations." ;
  rdfs:subClassOf obo:APO_0000073 .

obo:YPO_0000210 a rdfs:Class .

obo:APO_0000048 a rdfs:Class ;
  rdfs:label "virulence" ;
  rdfs:comment "The ability to cause disease in another organism." ;
  rdfs:subClassOf obo:APO_0000287 .

obo:YPO_0000244 a rdfs:Class .

obo:APO_0000026 a rdfs:Class ;
  rdfs:label "bipolar budding pattern" ;
  rdfs:comment "Localization of the emerging bud at the cell pole opposite the previous bud site." ;
  rdfs:subClassOf obo:APO_0000200 .

obo:APO_0000078 a rdfs:Class ;
  rdfs:label "protein secretion" ;
  rdfs:comment "Transport of proteins out of the cell by fusion of a membrane-bounded vesicle containing the proteins by fusion of the vesicle with the plasma membrane." ;
  rdfs:subClassOf obo:APO_0000129 .

obo:APO_0000275 a rdfs:Class ;
  rdfs:label "prion inheritance" ;
  rdfs:comment "The transmission of prions from a mother cell to a daughter cell during budding." ;
  rdfs:subClassOf obo:APO_0000274 .

obo:YPO_0000195 a rdfs:Class .

obo:YPO_0000215 a rdfs:Class .

obo:YPO_0000130 a rdfs:Class .

obo:APO_0000302 a rdfs:Class ;
  rdfs:label "vesicle distribution" ;
  rdfs:comment "The localization and placement of secretory, endocytic, or undefined vesicles within a cell or between separating cells." ;
  rdfs:subClassOf obo:APO_0000296 .

obo:YPO_0000232 a rdfs:Class .

obo:YPO_0000033 a rdfs:Class .

obo:YPO_0000264 a rdfs:Class .

obo:APO_0000067 a rdfs:Class ;
  rdfs:label "cell cycle arrest in G1 phase" ;
  rdfs:comment "OBSOLETE. This term was not defined before being made obsolete." .

obo:YPO_0000258 a rdfs:Class .

obo:YPO_0000269 a rdfs:Class .

obo:YPO_0000221 a rdfs:Class .

obo:APO_0000317 a rdfs:Class ;
  rdfs:label "replicative lifespan" ;
  rdfs:comment "The number of divisions that a cell undergoes before dying." ;
  rdfs:subClassOf obo:APO_0000030 .

obo:YPO_0000094 a rdfs:Class .

obo:APO_0000016 a rdfs:Class ;
  rdfs:label "not yet recorded" ;
  rdfs:comment "OBSOLETE. This term was not defined before being made obsolete." .

obo:YPO_0000044 a rdfs:Class .

obo:APO_0000056 a rdfs:Class ;
  rdfs:label "bud neck morphology" ;
  rdfs:comment "The size or shape of the bud neck, which is the region where the bud joins the mother cell." ;
  rdfs:subClassOf obo:APO_0000050 .

obo:APO_0000107 a rdfs:Class ;
  rdfs:label "growth rate in exponential phase" ;
  rdfs:comment "OBSOLETE: Growth rate in liquid culture during the exponential phase." .

obo:APO_0000011 a rdfs:Class ;
  rdfs:label "null mutant" ;
  rdfs:comment "The mutation abolishes completely the function of the gene product." ;
  rdfs:subClassOf obo:APO_0000006 .

obo:YPO_0000049 a rdfs:Class .

obo:YPO_0000179 a rdfs:Class .

obo:YPO_0000054 a rdfs:Class .

obo:APO_0000054 a rdfs:Class ;
  rdfs:label "cytoskeleton morphology" ;
  rdfs:comment "The size, shape, or appearance of the cytoskeleton." ;
  rdfs:subClassOf obo:APO_0000226 .

obo:YPO_0000136 a rdfs:Class .

obo:YPO_0000115 a rdfs:Class .

obo:APO_0000173 a rdfs:Class ;
  rdfs:label "Dosage Rescue" ;
  rdfs:subClassOf obo:APO_0000186 .

obo:YPO_0000147 a rdfs:Class .

obo:YPO_0000021 a rdfs:Class .

obo:APO_0000264 a rdfs:Class ;
  rdfs:label "cell cycle progression in metaphase" ;
  rdfs:comment "Progression of cells through metaphase during M phase of the mitotic cell cycle." ;
  rdfs:subClassOf obo:APO_0000258 .

obo:YPO_0000158 a rdfs:Class .

obo:APO_0000339 a rdfs:Class ;
  rdfs:label "ribophagy" ;
  rdfs:comment "A form of macroautophagy selective for ribosomes that occurs in response to starvation, damage or during a shift in environmental conditions." ;
  rdfs:subClassOf obo:APO_0000074 .

obo:YPO_0000079 a rdfs:Class .

obo:APO_0000252 a rdfs:Class ;
  rdfs:label "normal rate" ;
  rdfs:comment "Observed feature occurs at the same time relative to wild type." ;
  rdfs:subClassOf obo:APO_0000117 .

obo:YPO_0000184 a rdfs:Class .

obo:APO_0000044 a rdfs:Class ;
  rdfs:label "sporulation efficiency" ;
  rdfs:comment "The percentage of diploid cells in a population that undergo meiosis and form spores under sporulation-inducing conditions." ;
  rdfs:subClassOf obo:APO_0000041 .

obo:APO_0000149 a rdfs:Class ;
  rdfs:label "protein/peptide accumulation" ;
  rdfs:comment "Abundance of a specified peptide/protein; production to a certain level." ;
  rdfs:subClassOf obo:APO_0000094 .

obo:YPO_0000237 a rdfs:Class .

obo:APO_0000097 a rdfs:Class ;
  rdfs:label "auxotrophy" ;
  rdfs:comment "The inability of an organism to synthesize a specified organic compound required for its growth." ;
  rdfs:subClassOf obo:APO_0000096 .

obo:YPO_0000214 a rdfs:Class .

obo:APO_0000328 a rdfs:Class ;
  rdfs:label "unknown ploidy, classical genetics" ;
  rdfs:comment "Any classical genetics experiment carried out in a background where the ploidy of the mutation or strain is unknown." ;
  rdfs:subClassOf obo:APO_0000020 .

obo:YPO_0000022 a rdfs:Class .

obo:APO_0000089 a rdfs:Class ;
  rdfs:label "budding index" ;
  rdfs:comment "The percentage or fraction of budded cells in a population." ;
  rdfs:subClassOf obo:APO_0000024 .

obo:YPO_0000248 a rdfs:Class .

obo:YPO_0000225 a rdfs:Class .

obo:APO_0000118 a rdfs:Class ;
  rdfs:label "nuclear position" ;
  rdfs:comment "The location of the nucleus or nuclei within a cell or between separating cells." ;
  rdfs:subClassOf obo:APO_0000296 .

obo:APO_0000279 a rdfs:Class ;
  rdfs:label "haploid, classical genetics" ;
  rdfs:comment "Any classical genetics experiment carried out in a haploid background." ;
  rdfs:subClassOf obo:APO_0000020 .

obo:APO_0000306 a rdfs:Class ;
  rdfs:label "conidial germination" ;
  rdfs:comment "The production of viable cells arising from conidia, or asexual spores." ;
  rdfs:subClassOf obo:APO_0000295 .

obo:YPO_0000110 a rdfs:Class .

obo:YPO_0000010 a rdfs:Class .

obo:YPO_0000050 a rdfs:Class .

obo:APO_0000247 a rdfs:Class ;
  rdfs:label "decreased duration" ;
  rdfs:comment "Observed feature occurs over a decreased period of time relative to wild type." ;
  rdfs:subClassOf obo:APO_0000002 .

obo:YPO_0000065 a rdfs:Class .

obo:APO_0000268 a rdfs:Class ;
  rdfs:label "exit from G0 (stationary phase)" ;
  rdfs:comment "Exit of cells from the G0 or stationary phase of the mitotic cell cycle, where they move from a quiescent state to one where growth and division resumes in the G1 phase of the mitotic cell cycle." ;
  rdfs:subClassOf obo:APO_0000072 .

obo:YPO_0000226 a rdfs:Class .

obo:APO_0000156 a rdfs:Class ;
  rdfs:label "fermentative growth rate" ;
  rdfs:comment "OBSOLETE: The rate of growth in the presence of a fermentable carbon source." .

obo:APO_0000286 a rdfs:Class ;
  rdfs:label "aneuploid, systematic mutation set" ;
  rdfs:comment "Robotic generation and analysis of large-scale, genome-wide knockout sets carried out in an aneuploid background." ;
  rdfs:subClassOf obo:APO_0000235 .

obo:APO_0000134 a rdfs:Class ;
  rdfs:label "cell cycle arrest at the metaphase - anaphase transition" ;
  rdfs:comment "OBSOLETE. This term was not defined before being made obsolete." .

obo:YPO_0000107 a rdfs:Class .

obo:YPO_0000276 a rdfs:Class .

obo:APO_0000257 a rdfs:Class ;
  rdfs:label "cell cycle progression through the G2/M phase transition" ;
  rdfs:comment "Progression of cells from G2 phase to M phase of the mitotic cell cycle." ;
  rdfs:subClassOf obo:APO_0000253 .

obo:APO_0000138 a rdfs:Class ;
  rdfs:label "cell cycle arrest in late anaphase" ;
  rdfs:comment "OBSOLETE. This term was not defined before being made obsolete." .

obo:YPO_0000181 a rdfs:Class .

obo:APO_0000192 a rdfs:Class ;
  rdfs:label "phenotype assays" ;
  rdfs:subClassOf obo:APO_0000018 .

obo:APO_0000285 a rdfs:Class ;
  rdfs:label "haploid, systematic mutation set" ;
  rdfs:comment "Robotic generation and analysis of large-scale, genome-wide knockout sets carried out in a haploid background." ;
  rdfs:subClassOf obo:APO_0000235 .

obo:APO_0000297 a rdfs:Class ;
  rdfs:label "mitochondrial distribution" ;
  rdfs:comment "The localization and placement of mitochondria within a cell or between separating cells." ;
  rdfs:subClassOf obo:APO_0000296 .

obo:YPO_0000066 a rdfs:Class .

obo:APO_0000005 a rdfs:Class ;
  rdfs:label "absent" ;
  rdfs:comment "The observed feature is not detectable in the mutant." ;
  rdfs:subClassOf obo:APO_0000003 .

obo:YPO_0000259 a rdfs:Class .

obo:APO_0000296 a rdfs:Class ;
  rdfs:label "organelle distribution" ;
  rdfs:comment "The localization and placement of a particular organelle." ;
  rdfs:subClassOf obo:APO_0000073 .

obo:APO_0000145 a rdfs:Class ;
  rdfs:label "oxidative phosphorylation" ;
  rdfs:comment "The oxidation of nutrients to generate ATP, performed by enzymes of the mitochondrial inner membrane." ;
  rdfs:subClassOf obo:APO_0000102 .

obo:YPO_0000091 a rdfs:Class .

obo:YPO_0000011 a rdfs:Class .

obo:APO_0000140 a rdfs:Class ;
  rdfs:label "cell cycle arrest in G0 (stationary phase)" ;
  rdfs:comment "OBSOLETE. This term was not defined before being made obsolete." .

obo:APO_0000064 a rdfs:Class ;
  rdfs:label "liquid culture appearance" ;
  rdfs:comment "The appearance of a liquid culture of cells." ;
  rdfs:subClassOf obo:APO_0000158 .

obo:YPO_0000157 a rdfs:Class .

obo:APO_0000314 a rdfs:Class ;
  rdfs:label "cell lysis" ;
  rdfs:comment "The breaking apart of a fully formed cell." ;
  rdfs:subClassOf obo:APO_0000312 .

obo:YPO_0000203 a rdfs:Class .

obo:YPO_0000140 a rdfs:Class .

obo:APO_0000043 a rdfs:Class ;
  rdfs:label "spore wall formation" ;
  rdfs:comment "The biogenesis of specialized cell walls around developing ascospores." ;
  rdfs:subClassOf obo:APO_0000041 .

obo:APO_0000162 a rdfs:Class ;
  rdfs:label "Affinity Capture-MS" ;
  rdfs:subClassOf obo:APO_0000187 .

obo:YPO_0000274 a rdfs:Class .

obo:APO_0000243 a rdfs:Class ;
  rdfs:label "Golgi morphology" ;
  rdfs:comment "The size, shape or appearance of the Golgi apparatus or its parts." ;
  rdfs:subClassOf obo:APO_0000303 .

obo:APO_0000082 a rdfs:Class ;
  rdfs:label "osmotic stress resistance" ;
  rdfs:comment "The level of resistance to high or low osmolarity." ;
  rdfs:subClassOf obo:APO_0000087 .

obo:YPO_0000061 a rdfs:Class .

obo:YPO_0000207 a rdfs:Class .

obo:APO_0000263 a rdfs:Class ;
  rdfs:label "cell cycle progression in late anaphase" ;
  rdfs:comment "Progression of cells through late anaphase during M phase of the mitotic cell cycle." ;
  rdfs:subClassOf obo:APO_0000260 .

obo:APO_0000075 a rdfs:Class ;
  rdfs:label "endocytosis" ;
  rdfs:comment "The uptake and delivery of external materials or membrane constituents by the invagination of a small region of the plasma membrane to form a new membrane-bounded vesicle." ;
  rdfs:subClassOf obo:APO_0000073 .

obo:YPO_0000170 a rdfs:Class .

obo:APO_0000068 a rdfs:Class ;
  rdfs:label "cell cycle arrest at G2 phase" ;
  rdfs:comment "OBSOLETE. This term was not defined before being made obsolete." .

obo:YPO_0000016 a rdfs:Class .

obo:APO_0000202 a rdfs:Class ;
  rdfs:label "alkaline pH resistance" ;
  rdfs:comment "The level of resistance to alkaline pH." ;
  rdfs:subClassOf obo:APO_0000087 .

obo:APO_0000178 a rdfs:Class ;
  rdfs:label "Phenotypic Suppression" ;
  rdfs:subClassOf obo:APO_0000186 .

obo:APO_0000124 a rdfs:Class ;
  rdfs:label "pheromone-induced cell cycle arrest" ;
  rdfs:comment "Arrest of the cell cycle that occurs in response to the presence of mating pheromones from cells of the opposite mating type." ;
  rdfs:subClassOf obo:APO_0000037 .

obo:YPO_0000218 a rdfs:Class .

obo:YPO_0000001 a rdfs:Class .

obo:APO_0000117 a rdfs:Class ;
  rdfs:label "normal" ;
  rdfs:comment "The observed phenotype shows no detectable difference between the mutant and the wild type." ;
  rdfs:subClassOf obo:APO_0000001 .

obo:APO_0000232 a rdfs:Class ;
  rdfs:label "heterozygous diploid, large-scale survey" ;
  rdfs:comment "Any large-scale survey where the experiments carried our are in a heterozygous diploid background." ;
  rdfs:subClassOf obo:APO_0000114 .

obo:APO_0000303 a rdfs:Class ;
  rdfs:label "endomembrane system morphology" ;
  rdfs:comment "The size, shape, or appearance of components of the endomembrane system, which includes the nuclear envelope, endoplasmic reticulum, Golgi apparatus, peroxisomes, vacuoles, and endocytic and exocytic vesicles." ;
  rdfs:subClassOf obo:APO_0000226 .

obo:YPO_0000169 a rdfs:Class .

obo:YPO_0000032 a rdfs:Class .

obo:APO_0000096 a rdfs:Class ;
  rdfs:label "nutrient utilization" ;
  rdfs:comment "The ability to utilize specified substances as nutrients." ;
  rdfs:subClassOf obo:APO_0000094 .

obo:APO_0000325 a rdfs:Class ;
  rdfs:label "resistance to phagocytosis" ;
  rdfs:comment "The ability of a pathogen to evade or escape phagocytosis by host cells such as macrophages." ;
  rdfs:subClassOf obo:APO_0000287 .

obo:YPO_0000118 a rdfs:Class .

obo:YPO_0000043 a rdfs:Class .

obo:YPO_0000263 a rdfs:Class .

obo:APO_0000331 a rdfs:Class ;
  rdfs:label "capsule formation" ;
  rdfs:comment "The formation of a coating of extracellular polysaccharide material, as in fungi such a Cryptococcus." ;
  rdfs:subClassOf obo:APO_0000291 .

obo:YPO_0000077 a rdfs:Class .

obo:APO_0000209 a rdfs:Class ;
  rdfs:label "protein/peptide distribution" ;
  rdfs:comment "The location(s) where the specified protein is found within the cell." ;
  rdfs:subClassOf obo:APO_0000094 .

obo:APO_0000001 a rdfs:Class ;
  rdfs:label "qualifier" ;
  rdfs:comment "The direction of change in the mutant compared to wild type." .

obo:APO_0000320 a rdfs:Class ;
  rdfs:label "germ tube formation" ;
  rdfs:comment "Formation of an elongated evagination that develops from a yeast-form cell and continues growth to become a hyphal cell. The initiation of germ tube growth is referred to as the yeast-to-hyphal transition." ;
  rdfs:subClassOf obo:APO_0000027 .

obo:APO_0000033 a rdfs:Class ;
  rdfs:label "cell fusion" ;
  rdfs:comment "The fusion of individual cells from each partner during mating." ;
  rdfs:subClassOf obo:APO_0000032 .

obo:APO_0000213 a rdfs:Class ;
  rdfs:label "spindle morphology" ;
  rdfs:comment "The size, shape, or appearance of the mitotic or meiotic spindle." ;
  rdfs:subClassOf obo:APO_0000054 .

obo:APO_0000221 a rdfs:Class ;
  rdfs:label "septum formation" ;
  rdfs:comment "Formation of a septum between dividing cells." ;
  rdfs:subClassOf obo:APO_0000053 .

obo:APO_0000060 a rdfs:Class ;
  rdfs:label "colony appearance" ;
  rdfs:comment "The appearance of colonies of cells growing on a solid substrate." ;
  rdfs:subClassOf obo:APO_0000158 .

obo:APO_0000032 a rdfs:Class ;
  rdfs:label "mating response" ;
  rdfs:comment "The interaction between organisms leading to mating." ;
  rdfs:subClassOf obo:APO_0000031 .

obo:YPO_0000038 a rdfs:Class .

obo:APO_0000151 a rdfs:Class ;
  rdfs:label "null heterozygous diploid" ;
  rdfs:comment "OBSOLETE. Mutation abolishes function of one allele of the gene in a diploid strain." .

obo:APO_0000106 a rdfs:Class ;
  rdfs:label "vegetative growth" ;
  rdfs:comment "Growth under standard culture conditions (liquid or solid media)." ;
  rdfs:subClassOf obo:APO_0000094 .

obo:YPO_0000072 a rdfs:Class .

obo:YPO_0000229 a rdfs:Class .

obo:APO_0000253 a rdfs:Class ;
  rdfs:label "cell cycle progression" ;
  rdfs:comment "Progression of cells through the mitotic cell cycle." ;
  rdfs:subClassOf obo:APO_0000072 .

obo:YPO_0000168 a rdfs:Class .

obo:YPO_0000027 a rdfs:Class .

obo:YPO_0000055 a rdfs:Class .

obo:APO_0000022 a rdfs:Class ;
  rdfs:label "protein activity" ;
  rdfs:comment "The enzymatic or other activity of a protein." ;
  rdfs:subClassOf obo:APO_0000094 .

obo:APO_0000183 a rdfs:Class ;
  rdfs:label "Synthetic Lethality" ;
  rdfs:subClassOf obo:APO_0000186 .

obo:YPO_0000241 a rdfs:Class .

obo:YPO_0000098 a rdfs:Class .

obo:YPO_0000151 a rdfs:Class .

obo:APO_0000086 a rdfs:Class ;
  rdfs:label "X ray resistance" ;
  rdfs:comment "The level of resistance to X ray exposure." ;
  rdfs:subClassOf obo:APO_0000194 .

obo:APO_0000015 a rdfs:Class ;
  rdfs:label "unspecified" ;
  rdfs:comment "The mutation type is not specified in the reference." ;
  rdfs:subClassOf obo:APO_0000006 .

obo:APO_0000010 a rdfs:Class ;
  rdfs:label "gain of function" ;
  rdfs:comment "The mutation confers a new activity on the gene product." ;
  rdfs:subClassOf obo:APO_0000006 .

obo:YPO_0000265 a rdfs:Class .

obo:YPO_0000146 a rdfs:Class .

obo:YPO_0000236 a rdfs:Class .

obo:YPO_0000254 a rdfs:Class .

obo:APO_0000071 a rdfs:Class ;
  rdfs:label "cytokinesis" ;
  rdfs:comment "The division of the cytoplasm and the plasma membrane of a cell and its separation into two daughter cells." ;
  rdfs:subClassOf obo:APO_0000072 .

obo:YPO_0000271 a rdfs:Class .

obo:APO_0000113 a rdfs:Class ;
  rdfs:label "viable" ;
  rdfs:comment "The ability to grow under standard growth conditions. For S. cerevisiae, this means that visible colonies are formed from single cells on complete glucose medium (YPD) plates at 30 deg C under normal atmospheric conditions." ;
  rdfs:subClassOf obo:APO_0000217 .

obo:APO_0000336 a rdfs:Class ;
  rdfs:label "aneuploidy" ;
  rdfs:comment "The gain or loss of a chromosome, so that the cell has a number of chromosomes that is not a multiple of the usual complement. Aneuploidy may also be partial, affecting a large segment of a chromosome that is lost or translocated to a different chromosome." ;
  rdfs:subClassOf obo:APO_0000143 .

obo:YPO_0000162 a rdfs:Class .

obo:APO_0000080 a rdfs:Class ;
  rdfs:label "stress resistance" ;
  rdfs:comment "The level of resistance to stress conditions." ;
  rdfs:subClassOf obo:APO_0000066 .

obo:YPO_0000260 a rdfs:Class .

obo:APO_0000274 a rdfs:Class ;
  rdfs:label "prion state" ;
  rdfs:comment "The presence or absence of prions." ;
  rdfs:subClassOf obo:APO_0000066 .

obo:APO_0000055 a rdfs:Class ;
  rdfs:label "mitochondrial morphology" ;
  rdfs:comment "The size, shape, or appearance of the mitochondria." ;
  rdfs:subClassOf obo:APO_0000226 .

obo:YPO_0000005 a rdfs:Class .

obo:YPO_0000125 a rdfs:Class .

obo:APO_0000167 a rdfs:Class ;
  rdfs:label "Co-crystal Structure" ;
  rdfs:subClassOf obo:APO_0000187 .

obo:APO_0000128 a rdfs:Class ;
  rdfs:label "peroxisomal transport" ;
  rdfs:comment "Import of proteins into peroxisomes." ;
  rdfs:subClassOf obo:APO_0000129 .

obo:APO_0000050 a rdfs:Class ;
  rdfs:label "cellular morphology" ;
  rdfs:comment "The size or shape of cells." ;
  rdfs:subClassOf obo:APO_0000049 .

obo:APO_0000236 a rdfs:Class ;
  rdfs:label "homozygous diploid, systematic mutation set" ;
  rdfs:comment "Robotic generation and analysis of large-scale, genome-wide knockout sets carried out in a homozygous diploid background." ;
  rdfs:subClassOf obo:APO_0000235 .

obo:APO_0000260 a rdfs:Class ;
  rdfs:label "cell cycle progression in anaphase" ;
  rdfs:comment "Progression of cells through anaphase during M phase of the mitotic cell cycle." ;
  rdfs:subClassOf obo:APO_0000258 .

obo:YPO_0000135 a rdfs:Class .

obo:APO_0000066 a rdfs:Class ;
  rdfs:label "cellular processes" ;
  rdfs:comment "Processes occurring at the cellular level." ;
  rdfs:subClassOf obo:APO_0000017 .

obo:APO_0000093 a rdfs:Class ;
  rdfs:label "thermotolerance" ;
  rdfs:comment "The ability to survive a period of exposure to extremely high temperature (heat shock)." ;
  rdfs:subClassOf obo:APO_0000080 .

obo:APO_0000077 a rdfs:Class ;
  rdfs:label "nuclear transport" ;
  rdfs:comment "Transport of proteins or RNAs into or out of the nucleus." ;
  rdfs:subClassOf obo:APO_0000129 .

obo:APO_0000053 a rdfs:Class ;
  rdfs:label "cell wall morphology" ;
  rdfs:comment "The size, shape, or appearance of the cell wall." ;
  rdfs:subClassOf obo:APO_0000226 .

obo:YPO_0000257 a rdfs:Class .

obo:YPO_0000189 a rdfs:Class .

obo:APO_0000088 a rdfs:Class ;
  rdfs:label "drug resistance" ;
  rdfs:comment "OBSOLETE. This term was not defined before being made obsolete." .

obo:APO_0000195 a rdfs:Class ;
  rdfs:label "gamma ray resistance" ;
  rdfs:comment "The level of resistance to gamma radiation." ;
  rdfs:subClassOf obo:APO_0000194 .

obo:APO_0000038 a rdfs:Class ;
  rdfs:label "shmoo formation" ;
  rdfs:comment "An alteration of morphology such that the cell has a mating projection, formed in response to mating pheromone by cells of Saccharomyces and other fungi with similar life cycles. Named after the Al Capp cartoon character, whose shape it resembles." ;
  rdfs:subClassOf obo:APO_0000032 .

obo:APO_0000061 a rdfs:Class ;
  rdfs:label "colony color" ;
  rdfs:comment "The color of colonies of cells growing on a solid substrate." ;
  rdfs:subClassOf obo:APO_0000060 .

obo:APO_0000265 a rdfs:Class ;
  rdfs:label "cell cycle progression in telophase" ;
  rdfs:comment "Progression of cells through telophase, the last of the stages of mitosis during M phase of the mitotic cell cycle." ;
  rdfs:subClassOf obo:APO_0000258 .

obo:APO_0000091 a rdfs:Class ;
  rdfs:label "starvation resistance" ;
  rdfs:comment "The level of resistance to starvation conditions." ;
  rdfs:subClassOf obo:APO_0000080 .

obo:APO_0000329 a rdfs:Class ;
  rdfs:label "induction of host response" ;
  rdfs:comment "The induction of host immune cell differentiation, cytokine secretion, cytokine transcriptional regulation or other related host responses to infection by or contact with a microbe." ;
  rdfs:subClassOf obo:APO_0000287 .

obo:APO_0000301 a rdfs:Class ;
  rdfs:label "Golgi distribution" ;
  rdfs:comment "The localization and placement of the Golgi apparatus within a cell or between separating cells." ;
  rdfs:subClassOf obo:APO_0000296 .

obo:YPO_0000048 a rdfs:Class .

obo:YPO_0000216 a rdfs:Class .

obo:YPO_0000073 a rdfs:Class .

obo:YPO_0000178 a rdfs:Class .

obo:APO_0000027 a rdfs:Class ;
  rdfs:label "filamentous growth" ;
  rdfs:comment "Growth in a threadlike, filamentous shape." ;
  rdfs:subClassOf obo:APO_0000023 .

obo:APO_0000181 a rdfs:Class ;
  rdfs:label "Reconstituted Complex" ;
  rdfs:subClassOf obo:APO_0000187 .

obo:YPO_0000087 a rdfs:Class .

obo:APO_0000170 a rdfs:Class ;
  rdfs:label "Co-purification" ;
  rdfs:subClassOf obo:APO_0000187 .

obo:YPO_0000131 a rdfs:Class .

obo:YPO_0000233 a rdfs:Class .

obo:YPO_0000100 a rdfs:Class .

obo:APO_0000230 a rdfs:Class ;
  rdfs:label "heterozygous diploid" ;
  rdfs:comment "Classical genetics experiments carried out in a diploid background, where alleles of the gene being described are not identical." ;
  rdfs:subClassOf obo:APO_0000020 .

obo:APO_0000114 a rdfs:Class ;
  rdfs:label "large-scale survey" ;
  rdfs:comment "Generation and analysis of genome-wide sets of mutants that typically utilizes robotic methods." ;
  rdfs:subClassOf obo:APO_0000192 .

obo:APO_0000312 a rdfs:Class ;
  rdfs:label "cell death" ;
  rdfs:comment "The cessation of the life of an individual cell." ;
  rdfs:subClassOf obo:APO_0000066 .

obo:YPO_0000142 a rdfs:Class .

obo:APO_0000125 a rdfs:Class ;
  rdfs:label "utilization of phosphorus source" ;
  rdfs:comment "The ability to utilize the specified compound as a source of phosphorus." ;
  rdfs:subClassOf obo:APO_0000096 .

obo:YPO_0000153 a rdfs:Class .

obo:APO_0000229 a rdfs:Class ;
  rdfs:label "homozygous diploid" ;
  rdfs:comment "Classical genetics experiments carried out in a diploid background, where both alleles of the gene being described are identical." ;
  rdfs:subClassOf obo:APO_0000020 .

obo:YPO_0000185 a rdfs:Class .

obo:YPO_0000062 a rdfs:Class .

obo:APO_0000212 a rdfs:Class ;
  rdfs:label "bud morphology" ;
  rdfs:comment "The size or shape of the bud." ;
  rdfs:subClassOf obo:APO_0000050 .

obo:APO_0000318 a rdfs:Class ;
  rdfs:label "Affinity Capture-Luminescence" ;
  rdfs:comment "An interaction is inferred when a bait protein, tagged with luciferase, is enzymatically detected in immunoprecipitates of the prey protein as light emission. The prey protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag." ;
  rdfs:subClassOf obo:APO_0000187 .

obo:APO_0000226 a rdfs:Class ;
  rdfs:label "subcellular morphology" ;
  rdfs:comment "The size, shape, or appearance of subcellular organelles or structures." ;
  rdfs:subClassOf obo:APO_0000050 .

obo:APO_0000269 a rdfs:Class ;
  rdfs:label "cell cycle progression through the G1/S phase transition" ;
  rdfs:comment "Progression of cells from G1 phase to S phase of the mitotic cell cycle." ;
  rdfs:subClassOf obo:APO_0000253 .

obo:APO_0000057 a rdfs:Class ;
  rdfs:label "nuclear morphology" ;
  rdfs:comment "The size, shape, or appearance of the nucleus." ;
  rdfs:subClassOf obo:APO_0000303 .

obo:APO_0000009 a rdfs:Class ;
  rdfs:label "activation" ;
  rdfs:comment "The mutation increases the normal activity of a gene product." ;
  rdfs:subClassOf obo:APO_0000006 .

obo:YPO_0000196 a rdfs:Class .

obo:APO_0000201 a rdfs:Class ;
  rdfs:label "acid pH resistance" ;
  rdfs:comment "The level of resistance to acidic pH." ;
  rdfs:subClassOf obo:APO_0000087 .

obo:YPO_0000222 a rdfs:Class .

obo:YPO_0000205 a rdfs:Class .

obo:APO_0000049 a rdfs:Class ;
  rdfs:label "morphology" ;
  rdfs:comment "The size or shape of subcellular structures, cells, or multicellular structures." ;
  rdfs:subClassOf obo:APO_0000017 .

obo:APO_0000189 a rdfs:Class ;
  rdfs:label "Affinity Precipitation" ;
  rdfs:subClassOf obo:APO_0000187 .

obo:APO_0000241 a rdfs:Class ;
  rdfs:label "freeze-thaw resistance" ;
  rdfs:comment "The level of resistance to one or more cycles of freezing and thawing." ;
  rdfs:subClassOf obo:APO_0000080 .

obo:YPO_0000111 a rdfs:Class .

obo:YPO_0000121 a rdfs:Class .

obo:APO_0000135 a rdfs:Class ;
  rdfs:label "cell cycle arrest in anaphase" ;
  rdfs:comment "OBSOLETE. This term was not defined before being made obsolete." .

obo:YPO_0000160 a rdfs:Class .

obo:YPO_0000211 a rdfs:Class .

obo:APO_0000017 a rdfs:Class ;
  rdfs:label "observable" ;
  rdfs:comment "Features of ascomycete fungal cells, cultures, or colonies that can be detected, observed, measured, or monitored." .

obo:YPO_0000105 a rdfs:Class .

obo:APO_0000287 a rdfs:Class ;
  rdfs:label "interaction with host/environment" ;
  rdfs:comment "Processes relating to interaction with the environment or with a host organism." ;
  rdfs:subClassOf obo:APO_0000017 .

obo:YPO_0000070 a rdfs:Class .

obo:APO_0000206 a rdfs:Class ;
  rdfs:label "heterozygous diploid" ;
  rdfs:comment "OBSOLETE. This term was not defined before being made obsolete." .

obo:APO_0000012 a rdfs:Class ;
  rdfs:label "repressible" ;
  rdfs:comment "The mutation leads to reduction of levels of the gene product, often through the use of a repressible promoter." ;
  rdfs:subClassOf obo:APO_0000006 .

obo:YPO_0000080 a rdfs:Class .

obo:APO_0000307 a rdfs:Class ;
  rdfs:label "anaerobic growth" ;
  rdfs:comment "Growth in the absence of oxygen." ;
  rdfs:subClassOf obo:APO_0000210 .

obo:YPO_0000051 a rdfs:Class .

obo:APO_0000251 a rdfs:Class ;
  rdfs:label "premature" ;
  rdfs:comment "Observed feature occurs too soon, existing before the proper or usual time compared to wild type." ;
  rdfs:subClassOf obo:APO_0000002 .

obo:YPO_0000238 a rdfs:Class .

obo:YPO_0000116 a rdfs:Class .

obo:YPO_0000227 a rdfs:Class .

obo:YPO_0000174 a rdfs:Class .

obo:YPO_0000268 a rdfs:Class .

obo:APO_0000216 a rdfs:Class ;
  rdfs:label "fitness" ;
  rdfs:comment "The ability of an organism to reproduce and to produce viable progeny." ;
  rdfs:subClassOf obo:APO_0000017 .

obo:APO_0000098 a rdfs:Class ;
  rdfs:label "utilization of carbon source" ;
  rdfs:comment "The ability to utilize the specified compound as a carbon source." ;
  rdfs:subClassOf obo:APO_0000096 .

obo:YPO_0000040 a rdfs:Class .

obo:APO_0000298 a rdfs:Class ;
  rdfs:label "peroxisomal distribution" ;
  rdfs:comment "The localization and placement of peroxisomes within a cell or between separating cells." ;
  rdfs:subClassOf obo:APO_0000296 .

obo:APO_0000002 a rdfs:Class ;
  rdfs:label "abnormal" ;
  rdfs:comment "The observed phenotype is detectably different from that in the wild type." ;
  rdfs:subClassOf obo:APO_0000001 .

obo:APO_0000200 a rdfs:Class ;
  rdfs:label "budding pattern" ;
  rdfs:comment "The pattern with which buds emerge from a mother cell." ;
  rdfs:subClassOf obo:APO_0000024 .

obo:APO_0000076 a rdfs:Class ;
  rdfs:label "mitochondrial transport" ;
  rdfs:comment "Import of proteins into mitochondria." ;
  rdfs:subClassOf obo:APO_0000129 .

obo:APO_0000237 a rdfs:Class ;
  rdfs:label "heterozygous diploid, systematic mutation set" ;
  rdfs:comment "Robotic generation and analysis of large-scale, genome-wide mutation sets carried out in a heterozygous diploid." ;
  rdfs:subClassOf obo:APO_0000235 .

obo:APO_0000335 a rdfs:Class ;
  rdfs:label "size of nucleolus" ;
  rdfs:comment "The size of the nucleolus." ;
  rdfs:subClassOf obo:APO_0000273 .

obo:APO_0000240 a rdfs:Class ;
  rdfs:label "mitophagy" ;
  rdfs:comment "A form of autophagy selective for mitochondria that occurs in response to starvation, damage or during a shift in environmental conditions. The process can be further subdivided into micromitophagy, the engulfment of a cluster of mitochondria at the vacuole surface, and macromitophagy, the sequestration of individual mitochondria by a double-membrane vesicle, followed by fusion with the vacuole." ;
  rdfs:subClassOf obo:APO_0000074 .

obo:APO_0000205 a rdfs:Class ;
  rdfs:label "ionic stress resistance" ;
  rdfs:comment "The level of resistance to ionic stress." ;
  rdfs:subClassOf obo:APO_0000087 .

obo:YPO_0000152 a rdfs:Class .

obo:APO_0000217 a rdfs:Class ;
  rdfs:label "essentiality" ;
  rdfs:comment "The essentiality of a gene for survival under standard conditions for growth of that organism." ;
  rdfs:subClassOf obo:APO_0000017 .

obo:APO_0000121 a rdfs:Class ;
  rdfs:label "bud direction" ;
  rdfs:comment "OBSOLETE: This term was not defined before being obsoleted." .

obo:APO_0000139 a rdfs:Class ;
  rdfs:label "cell cycle arrest in telophase" ;
  rdfs:comment "OBSOLETE. This term was not defined before being made obsolete." .

obo:YPO_0000217 a rdfs:Class .

obo:APO_0000045 a rdfs:Class ;
  rdfs:label "sterile" ;
  rdfs:comment "The sterile phenotype is the inability to mate with cells of the opposite mating type under conditions that normally promote mating." ;
  rdfs:subClassOf obo:APO_0000031 .

obo:APO_0000179 a rdfs:Class ;
  rdfs:label "Protein-RNA" ;
  rdfs:subClassOf obo:APO_0000187 .

obo:APO_0000222 a rdfs:Class ;
  rdfs:label "chemical compound excretion" ;
  rdfs:comment "The excretion from the cell of a specified chemical compound." ;
  rdfs:subClassOf obo:APO_0000094 .

obo:YPO_0000139 a rdfs:Class .

obo:APO_0000324 a rdfs:Class ;
  rdfs:label "resistance to killing by host cells" ;
  rdfs:comment "The ability of a pathogen to survive an attack by host cells such as neutrophils." ;
  rdfs:subClassOf obo:APO_0000287 .

obo:APO_0000161 a rdfs:Class ;
  rdfs:label "multiple" ;
  rdfs:comment "OBSOLETE. This term was not defined before being made obsolete." .

obo:YPO_0000188 a rdfs:Class .

obo:YPO_0000228 a rdfs:Class .

obo:APO_0000244 a rdfs:Class ;
  rdfs:label "PCA" ;
  rdfs:subClassOf obo:APO_0000187 .

obo:APO_0000295 a rdfs:Class ;
  rdfs:label "conidiation" ;
  rdfs:comment "The formation of conidia, which are asexual spores." ;
  rdfs:subClassOf obo:APO_0000023 .

obo:APO_0000262 a rdfs:Class ;
  rdfs:label "cell cycle progression in mid anaphase" ;
  rdfs:comment "Progression of cells through mid anaphase during M phase of the mitotic cell cycle." ;
  rdfs:subClassOf obo:APO_0000260 .

obo:YPO_0000206 a rdfs:Class .

obo:APO_0000099 a rdfs:Class ;
  rdfs:label "utilization of nitrogen source" ;
  rdfs:comment "The ability to utilize the specified compound as a source of nitrogen." ;
  rdfs:subClassOf obo:APO_0000096 .

obo:YPO_0000163 a rdfs:Class .

obo:YPO_0000171 a rdfs:Class .

obo:YPO_0000239 a rdfs:Class .

obo:APO_0000146 a rdfs:Class ;
  rdfs:label "systematic repressible mutation set" ;
  rdfs:comment "OBSOLETE. This term was not defined before being made obsolete." .

obo:YPO_0000261 a rdfs:Class .

obo:APO_0000028 a rdfs:Class ;
  rdfs:label "invasive growth" ;
  rdfs:comment "Penetration of cells into a solid substrate during filamentous growth." ;
  rdfs:subClassOf obo:APO_0000027 .

obo:YPO_0000128 a rdfs:Class .

obo:APO_0000157 a rdfs:Class ;
  rdfs:label "utilization of iron source" ;
  rdfs:comment "The ability to utilize the specified compound as a source of iron." ;
  rdfs:subClassOf obo:APO_0000096 .

obo:YPO_0000200 a rdfs:Class .

obo:APO_0000042 a rdfs:Class ;
  rdfs:label "spore germination" ;
  rdfs:comment "The production of viable cells arising from sexual spores." ;
  rdfs:subClassOf obo:APO_0000041 .

obo:YPO_0000182 a rdfs:Class .

obo:YPO_0000275 a rdfs:Class .

obo:YPO_0000250 a rdfs:Class .

obo:APO_0000258 a rdfs:Class ;
  rdfs:label "cell cycle progression in M phase" ;
  rdfs:comment "Progression of cells through the M phase of the mitotic cell cycle, the phase in which mitosis occurs." ;
  rdfs:subClassOf obo:APO_0000253 .

obo:APO_0000083 a rdfs:Class ;
  rdfs:label "oxidative stress resistance" ;
  rdfs:comment "The level of resistance to oxidative stress." ;
  rdfs:subClassOf obo:APO_0000087 .

obo:APO_0000330 a rdfs:Class ;
  rdfs:label "haploproficient" ;
  rdfs:comment "The heterozygous diploid displays an increased growth rate relative to a diploid that is homozygous wild type at that locus." ;
  rdfs:subClassOf obo:APO_0000216 .

obo:YPO_0000004 a rdfs:Class .

obo:YPO_0000193 a rdfs:Class .

obo:APO_0000254 a rdfs:Class ;
  rdfs:label "cell cycle progression in G2 phase" ;
  rdfs:comment "Progression of cells through the G2 phase or second gap phase of the mitotic cell cycle, the interval between the completion of DNA synthesis and the beginning of mitosis." ;
  rdfs:subClassOf obo:APO_0000253 .

obo:APO_0000271 a rdfs:Class ;
  rdfs:label "RNA modification" ;
  rdfs:comment "Covalent modification of a specified RNA; type of modification specified." ;
  rdfs:subClassOf obo:APO_0000094 .

obo:YPO_0000253 a rdfs:Class .

obo:APO_0000065 a rdfs:Class ;
  rdfs:label "flocculation" ;
  rdfs:comment "Adhesion and aggregation of cells in liquid culture to produce clumps of cells." ;
  rdfs:subClassOf obo:APO_0000064 .

obo:APO_0000233 a rdfs:Class ;
  rdfs:label "homozygous diploid, competitive growth" ;
  rdfs:comment "Any competitive growth experiment carried out in a homozygous diploid background." ;
  rdfs:subClassOf obo:APO_0000021 .

obo:YPO_0000240 a rdfs:Class .

obo:YPO_0000156 a rdfs:Class .

obo:APO_0000090 a rdfs:Class ;
  rdfs:label "metal resistance" ;
  rdfs:comment "The level of resistance to a specific metal or metals." ;
  rdfs:subClassOf obo:APO_0000087 .

obo:APO_0000284 a rdfs:Class ;
  rdfs:label "aneuploid, competitive growth" ;
  rdfs:comment "Any competitive growth experiment carried out in an aneuploid background." ;
  rdfs:subClassOf obo:APO_0000021 .

obo:APO_0000006 a rdfs:Class ;
  rdfs:label "mutant_type" ;
  rdfs:comment "A description of the effect of the mutation on the gene product function." .

obo:APO_0000168 a rdfs:Class ;
  rdfs:label "Co-fractionation" ;
  rdfs:subClassOf obo:APO_0000187 .

obo:YPO_0000145 a rdfs:Class .

obo:APO_0000072 a rdfs:Class ;
  rdfs:label "mitotic cell cycle" ;
  rdfs:comment "A cycle of DNA replication and cell division via mitosis." ;
  rdfs:subClassOf obo:APO_0000066 .

obo:APO_0000282 a rdfs:Class ;
  rdfs:label "aneuploid, classical genetics" ;
  rdfs:comment "Any classical genetics experiment carried out in an aneuploid background, where the strain carries more or fewer copies than normal of a large chromosomal region, or of one or more entire chromosomes." ;
  rdfs:subClassOf obo:APO_0000020 .

obo:APO_0000020 a rdfs:Class ;
  rdfs:label "classical genetics" ;
  rdfs:comment "Phenotypic analysis of one or a few mutant strains in small-scale, focused experiments that do not require knowledge of the entire genome sequence." ;
  rdfs:subClassOf obo:APO_0000192 .

obo:YPO_0000272 a rdfs:Class .

obo:APO_0000150 a rdfs:Class ;
  rdfs:label "null homozygous diploid" ;
  rdfs:comment "OBSOLETE. Mutation abolishes function of both alleles of the gene in a diploid strain." .

obo:APO_0000184 a rdfs:Class ;
  rdfs:label "Synthetic Rescue" ;
  rdfs:subClassOf obo:APO_0000186 .

obo:YPO_0000120 a rdfs:Class .

obo:APO_0000273 a rdfs:Class ;
  rdfs:label "nucleolar morphology" ;
  rdfs:comment "The size, shape, or appearance of the nucleolus or its parts." ;
  rdfs:subClassOf obo:APO_0000057 .

obo:YPO_0000037 a rdfs:Class .

obo:APO_0000313 a rdfs:Class ;
  rdfs:label "autolysis" ;
  rdfs:comment "A regulated form of cell death that occurs in stationary phase mycelial cultures of filamentous fungi, often in response to carbon starvation. It is characterized by cell wall degradation, hyphal fragmentation and vacuolization, production of intracellular and extracellular hydrolases, and release of ammonia." ;
  rdfs:subClassOf obo:APO_0000312 .

obo:APO_0000248 a rdfs:Class ;
  rdfs:label "increased duration" ;
  rdfs:comment "Observed feature occurs over an increased period of time relative to wild type." ;
  rdfs:subClassOf obo:APO_0000002 .

obo:YPO_0000199 a rdfs:Class .

obo:YPO_0000015 a rdfs:Class .

obo:APO_0000110 a rdfs:Class ;
  rdfs:label "competitive fitness" ;
  rdfs:comment "The ability of a mutant strain to grow or survive under conditions of direct competition with wild type or other mutants." ;
  rdfs:subClassOf obo:APO_0000216 .

obo:APO_0000172 a rdfs:Class ;
  rdfs:label "Dosage Lethality" ;
  rdfs:subClassOf obo:APO_0000186 .

obo:YPO_0000134 a rdfs:Class .

obo:APO_0000034 a rdfs:Class ;
  rdfs:label "mating efficiency" ;
  rdfs:comment "The proportion of cells within a population that are able to mate." ;
  rdfs:subClassOf obo:APO_0000032 .

obo:APO_0000031 a rdfs:Class ;
  rdfs:label "sexual cycle" ;
  rdfs:comment "The process of sexual reproduction." ;
  rdfs:subClassOf obo:APO_0000023 .

obo:YPO_0000097 a rdfs:Class .

obo:APO_0000023 a rdfs:Class ;
  rdfs:label "development" ;
  rdfs:comment "Developmental processes." ;
  rdfs:subClassOf obo:APO_0000017 .

obo:APO_0000293 a rdfs:Class ;
  rdfs:label "utilization of zinc source" ;
  rdfs:comment "The ability to utilize the specified compound as a source of zinc." ;
  rdfs:subClassOf obo:APO_0000096 .

obo:APO_0000087 a rdfs:Class ;
  rdfs:label "resistance to chemicals" ;
  rdfs:comment "The level of resistance to exposure to chemicals." ;
  rdfs:subClassOf obo:APO_0000080 .

obo:YPO_0000167 a rdfs:Class .

obo:APO_0000276 a rdfs:Class ;
  rdfs:label "prion formation" ;
  rdfs:comment "The conversion from the state of being prion-free to the state of having prions." ;
  rdfs:subClassOf obo:APO_0000274 .

obo:APO_0000103 a rdfs:Class ;
  rdfs:label "respiratory growth rate" ;
  rdfs:comment "OBSOLETE." .

obo:YPO_0000083 a rdfs:Class .

obo:YPO_0000026 a rdfs:Class .

obo:YPO_0000197 a rdfs:Class .

obo:YPO_0000234 a rdfs:Class .

obo:APO_0000169 a rdfs:Class ;
  rdfs:label "Co-localization" ;
  rdfs:subClassOf obo:APO_0000187 .

obo:YPO_0000008 a rdfs:Class .

obo:YPO_0000003 a rdfs:Class .

obo:APO_0000171 a rdfs:Class ;
  rdfs:label "Dosage Growth Defect" ;
  rdfs:subClassOf obo:APO_0000186 .

obo:APO_0000052 a rdfs:Class ;
  rdfs:label "cell size" ;
  rdfs:comment "The size of the cell." ;
  rdfs:subClassOf obo:APO_0000050 .

obo:APO_0000154 a rdfs:Class ;
  rdfs:label "petite-negative" ;
  rdfs:comment "The petite-negative phenotype arises from mutation in a nuclear gene that is not essential in an otherwise wild-type strain with an intact mitochondrial genome, but becomes essential in strains lacking the mitochondrial genome, referred to as rho- or rho0. Petite-negative strains cannot grow on fermentable carbon sources (e.g., glucose) in the absence of an intact mitochondrial genome. This phenotype is often assayed as the inability grow in the presence of ethidium bromide, which causes the loss of the mitochondrial genome." ;
  rdfs:subClassOf obo:APO_0000102 .

obo:APO_0000115 a rdfs:Class ;
  rdfs:label "other method" ;
  rdfs:comment "OBSOLETE. This term defined as 'novel techniques' has been obsoleted as it was a remnant of the original mutant types that has not been used." .

obo:YPO_0000099 a rdfs:Class .

obo:APO_0000270 a rdfs:Class ;
  rdfs:label "endoplasmic reticulum morphology" ;
  rdfs:comment "The size, shape, or appearance of the endoplasmic reticulum (ER) or its parts." ;
  rdfs:subClassOf obo:APO_0000303 .

obo:YPO_0000014 a rdfs:Class .

obo:APO_0000132 a rdfs:Class ;
  rdfs:label "RNA localization" ;
  rdfs:comment "Localization of specific RNAs within the cell." ;
  rdfs:subClassOf obo:APO_0000073 .

obo:YPO_0000112 a rdfs:Class .

obo:APO_0000341 a rdfs:Class ;
  rdfs:label "nucleophagy" ;
  rdfs:comment "Selective degradation of nucleoplasm that occurs upon nitrogen starvation, in which parts of the nucleus and perinuclear ER are packaged into autophagosomes and delivered to the vacuole for degradation. In S. cerevisiae, Atg39p is involved in this process." ;
  rdfs:subClassOf obo:APO_0000074 .

obo:APO_0000131 a rdfs:Class ;
  rdfs:label "protein/peptide modification" ;
  rdfs:comment "The covalent modification of a specified protein." ;
  rdfs:subClassOf obo:APO_0000094 .

obo:APO_0000013 a rdfs:Class ;
  rdfs:label "reduction of function" ;
  rdfs:comment "The mutation reduces the activity of the gene product." ;
  rdfs:subClassOf obo:APO_0000006 .

obo:YPO_0000036 a rdfs:Class .

obo:YPO_0000084 a rdfs:Class .

obo:YPO_0000251 a rdfs:Class .

obo:YPO_0000019 a rdfs:Class .

obo:APO_0000147 a rdfs:Class ;
  rdfs:label "heat sensitivity" ;
  rdfs:comment "Sensitivity to temperatures that are higher than optimal growth temperature." ;
  rdfs:subClassOf obo:APO_0000092 .

obo:APO_0000281 a rdfs:Class ;
  rdfs:label "haploid, large-scale survey" ;
  rdfs:comment "Any large-scale survey experiment carried out in a haploid background." ;
  rdfs:subClassOf obo:APO_0000114 .

obo:YPO_0000093 a rdfs:Class .

obo:APO_0000092 a rdfs:Class ;
  rdfs:label "temperature sensitive growth" ;
  rdfs:comment "Sensitivity to temperatures that are higher or lower than optimal growth temperature." ;
  rdfs:subClassOf obo:APO_0000080 .

obo:YPO_0000074 a rdfs:Class .

obo:APO_0000250 a rdfs:Class ;
  rdfs:label "arrested" ;
  rdfs:comment "Observed feature does not occur in a given time period relative to wild type." ;
  rdfs:subClassOf obo:APO_0000002 .

obo:APO_0000188 a rdfs:Class ;
  rdfs:label "Affinity Chromatography" ;
  rdfs:subClassOf obo:APO_0000187 .

obo:YPO_0000242 a rdfs:Class .

obo:APO_0000094 a rdfs:Class ;
  rdfs:label "metabolism and growth" ;
  rdfs:comment "Processes relating to metabolism and growth." ;
  rdfs:subClassOf obo:APO_0000017 .

obo:APO_0000319 a rdfs:Class ;
  rdfs:label "chlamydospore formation" ;
  rdfs:comment "Formation of chlamydospores, which are large, asexual, one-celled spores with a thickened, refractile cell wall that are borne on the ends of suspensor cells attached to hyphae or pseudohyphae." ;
  rdfs:subClassOf obo:APO_0000023 .

obo:YPO_0000090 a rdfs:Class .

obo:APO_0000058 a rdfs:Class ;
  rdfs:label "peroxisomal morphology" ;
  rdfs:comment "The size, shape, or appearance of the peroxisomes." ;
  rdfs:subClassOf obo:APO_0000303 .

obo:APO_0000018 a rdfs:Class ;
  rdfs:label "experiment_type" ;
  rdfs:comment "A description of the experimental approach." .

obo:APO_0000084 a rdfs:Class ;
  rdfs:label "radiation resistance" ;
  rdfs:comment "The level of resistance to radiation." ;
  rdfs:subClassOf obo:APO_0000080 .

obo:APO_0000160 a rdfs:Class ;
  rdfs:label "hyphal growth" ;
  rdfs:subClassOf obo:APO_0000027 .

obo:YPO_0000223 a rdfs:Class .

obo:YPO_0000052 a rdfs:Class .

obo:YPO_0000177 a rdfs:Class .

obo:APO_0000199 a rdfs:Class ;
  rdfs:label "chitin deposition" ;
  rdfs:comment "The pattern of chitin deposition in the cell wall." ;
  rdfs:subClassOf obo:APO_0000053 .

obo:YPO_0000081 a rdfs:Class .

obo:YPO_0000101 a rdfs:Class .

obo:APO_0000308 a rdfs:Class ;
  rdfs:label "fermentative growth" ;
  rdfs:comment "Growth while utilizing a fermentable carbon source." ;
  rdfs:subClassOf obo:APO_0000101 .

obo:APO_0000165 a rdfs:Class ;
  rdfs:label "Affinity Capture-Western" ;
  rdfs:subClassOf obo:APO_0000187 .

obo:APO_0000109 a rdfs:Class ;
  rdfs:label "survival rate in stationary phase" ;
  rdfs:comment "The rate of survival in liquid stationary phase cultures." ;
  rdfs:subClassOf obo:APO_0000106 .

obo:APO_0000175 a rdfs:Class ;
  rdfs:label "FRET" ;
  rdfs:subClassOf obo:APO_0000187 .

obo:YPO_0000117 a rdfs:Class .

obo:APO_0000158 a rdfs:Class ;
  rdfs:label "culture appearance" ;
  rdfs:comment "The appearance of a population of cells." ;
  rdfs:subClassOf obo:APO_0000049 .

obo:YPO_0000063 a rdfs:Class .

obo:APO_0000211 a rdfs:Class ;
  rdfs:label "anaerobic growth rate" ;
  rdfs:comment "OBSOLETE: The rate of growth in the absence of oxygen." .

obo:APO_0000266 a rdfs:Class ;
  rdfs:label "cell cycle progression in S phase" ;
  rdfs:comment "Progression of cells through S phase, the part of the mitotic cell cycle where DNA synthesis occurs." ;
  rdfs:subClassOf obo:APO_0000253 .

obo:APO_0000227 a rdfs:Class ;
  rdfs:label "cell cycle arrest in S phase" ;
  rdfs:comment "OBSOLETE. Arrest of cells in the S phase of the cell cycle, the phase in which DNA replication occurs." .

obo:YPO_0000212 a rdfs:Class .

obo:APO_0000292 a rdfs:Class ;
  rdfs:label "secondary metabolite production" ;
  rdfs:comment "The production of secondary metabolites, which are compounds that are not directly involved in normal growth, development or reproduction." ;
  rdfs:subClassOf obo:APO_0000094 .

obo:APO_0000008 a rdfs:Class ;
  rdfs:label "overexpression" ;
  rdfs:comment "The mutation causes expression of the otherwise normal gene product to higher levels than wild-type." ;
  rdfs:subClassOf obo:APO_0000006 .

obo:YPO_0000025 a rdfs:Class .

obo:APO_0000180 a rdfs:Class ;
  rdfs:label "Protein-peptide" ;
  rdfs:subClassOf obo:APO_0000187 .

obo:APO_0000239 a rdfs:Class ;
  rdfs:label "pexophagy" ;
  rdfs:comment "A form of autophagy selective for peroxisomes that occurs in response to starvation, damage or as a homeostatic mechanism to regulate the levels of this organelle. Pexophagy can be further subdivided into micropexophagy, the engulfment of a cluster of peroxisomes at the vacuole surface and macropexophagy, the sequestration of individual peroxisomes by a double-membrane vesicle, followed by fusion with the vacuole." ;
  rdfs:subClassOf obo:APO_0000074 .

obo:APO_0000228 a rdfs:Class ;
  rdfs:label "dominant negative" ;
  rdfs:comment "The mutation results in a gene product that interferes with the function of the normal, wild-type gene product." ;
  rdfs:subClassOf obo:APO_0000006 .

obo:APO_0000207 a rdfs:Class ;
  rdfs:label "homozygous diploid" ;
  rdfs:comment "OBSOLETE. This term was not defined before being made obsolete." .

obo:YPO_0000201 a rdfs:Class .

obo:YPO_0000106 a rdfs:Class .

obo:YPO_0000190 a rdfs:Class .

obo:YPO_0000186 a rdfs:Class .

obo:YPO_0000122 a rdfs:Class .

obo:YPO_0000175 a rdfs:Class .

obo:APO_0000039 a rdfs:Class ;
  rdfs:label "meiosis" ;
  rdfs:comment "A specialized cell division in which a single diploid cell undergoes two nuclear divisions following a single round of DNA replication in order to produce four daughter cells that contain half the number of chromosomes as the diploid cell." ;
  rdfs:subClassOf obo:APO_0000031 .

obo:APO_0000196 a rdfs:Class ;
  rdfs:label "mating type switching" ;
  rdfs:comment "Conversion of a cell of one mating type to a different mating type." ;
  rdfs:subClassOf obo:APO_0000031 .

obo:YPO_0000030 a rdfs:Class .

obo:YPO_0000164 a rdfs:Class .

obo:APO_0000024 a rdfs:Class ;
  rdfs:label "budding" ;
  rdfs:comment "The formation of a bud, which develops into a daughter cell during asexual reproduction." ;
  rdfs:subClassOf obo:APO_0000023 .

obo:YPO_0000138 a rdfs:Class .

obo:APO_0000029 a rdfs:Class ;
  rdfs:label "pseudohyphal growth" ;
  rdfs:comment "Growth in a pattern that occurs in conditions of nitrogen limitation and abundant fermentable carbon source. Cells become elongated, switch to a unipolar budding pattern, remain physically attached to each other, and invade the growth substrate." ;
  rdfs:subClassOf obo:APO_0000027 .

obo:APO_0000164 a rdfs:Class ;
  rdfs:label "interactions" ;
  rdfs:subClassOf obo:APO_0000018 .

obo:APO_0000218 a rdfs:Class ;
  rdfs:label "redox state" ;
  rdfs:comment "The balance of oxidized and reduced molecules in the cell. Respiration and various environmental factors cause formation of reactive oxygen species which can oxidize and damage cellular components." ;
  rdfs:subClassOf obo:APO_0000094 .

obo:APO_0000126 a rdfs:Class ;
  rdfs:label "nuclear import" ;
  rdfs:comment "Transport of proteins or RNAs into or out of the nucleus." ;
  rdfs:subClassOf obo:APO_0000077 .

obo:APO_0000238 a rdfs:Class ;
  rdfs:label "cell cycle arrest at the G2/M phase transition" ;
  rdfs:comment "OBSOLETE. Arrest of cells at the transition between the G2 and M phases of the mitotic cell cycle." .

obo:YPO_0000133 a rdfs:Class .

obo:YPO_0000267 a rdfs:Class .

obo:APO_0000277 a rdfs:Class ;
  rdfs:label "prion loss" ;
  rdfs:comment "The conversion from the state of having prions to the state of being prion-free." ;
  rdfs:subClassOf obo:APO_0000274 .

obo:YPO_0000176 a rdfs:Class .

obo:APO_0000334 a rdfs:Class ;
  rdfs:label "innate thermotolerance" ;
  rdfs:comment "The natural or innate ability of a cell to survive a period of exposure to an acute heat shock without pretreatment." ;
  rdfs:subClassOf obo:APO_0000093 .

obo:YPO_0000096 a rdfs:Class .

obo:APO_0000185 a rdfs:Class ;
  rdfs:label "Two-hybrid" ;
  rdfs:subClassOf obo:APO_0000187 .

obo:APO_0000245 a rdfs:Class ;
  rdfs:label "decreased rate" ;
  rdfs:comment "Observed feature is decreased with respect to time compared to that in the wild type (slower)." ;
  rdfs:subClassOf obo:APO_0000002 .

obo:YPO_0000127 a rdfs:Class .

obo:APO_0000100 a rdfs:Class ;
  rdfs:label "nutrient uptake" ;
  rdfs:comment "Uptake of nutrients into a cell." ;
  rdfs:subClassOf obo:APO_0000096 .

obo:YPO_0000029 a rdfs:Class .

obo:YPO_0000155 a rdfs:Class .

obo:APO_0000030 a rdfs:Class ;
  rdfs:label "lifespan" ;
  rdfs:comment "The duration of the life of an individual organism." ;
  rdfs:subClassOf obo:APO_0000023 .

obo:YPO_0000041 a rdfs:Class .

obo:APO_0000136 a rdfs:Class ;
  rdfs:label "cell cycle arrest in early anaphase" ;
  rdfs:comment "OBSOLETE. This term was not defined before being made obsolete." .

obo:APO_0000283 a rdfs:Class ;
  rdfs:label "aneuploid, large-scale survey" ;
  rdfs:comment "Any large-scale survey experiment carried out in an aneuploid background." ;
  rdfs:subClassOf obo:APO_0000114 .

obo:YPO_0000166 a rdfs:Class .

obo:APO_0000255 a rdfs:Class ;
  rdfs:label "cell cycle progression in G1 phase" ;
  rdfs:comment "Progression of cells through the G1 or first gap phase of the mitotic cell cycle, the interval between the completion of mitosis and the beginning of DNA synthesis." ;
  rdfs:subClassOf obo:APO_0000253 .

obo:APO_0000003 a rdfs:Class ;
  rdfs:label "decreased" ;
  rdfs:comment "The observed feature is decreased compared to that in the wild type (slower, weaker, lower, smaller, etc.)." ;
  rdfs:subClassOf obo:APO_0000002 .

obo:APO_0000322 a rdfs:Class ;
  rdfs:label "Negative Genetic" ;
  rdfs:subClassOf obo:APO_0000186 .

obo:YPO_0000069 a rdfs:Class .

obo:APO_0000223 a rdfs:Class ;
  rdfs:label "mating projection morphology" ;
  rdfs:comment "The outward appearance or shape of the mating projection." ;
  rdfs:subClassOf obo:APO_0000050 .

obo:APO_0000323 a rdfs:Class ;
  rdfs:label "Positive Genetic" ;
  rdfs:subClassOf obo:APO_0000186 .

obo:APO_0000019 a rdfs:Class ;
  rdfs:label "systematic null mutation set" ;
  rdfs:comment "OBSOLETE. Robotic generation and analysis of large-scale, genome-wide knockout sets." .

obo:YPO_0000109 a rdfs:Class .

obo:YPO_0000187 a rdfs:Class .

obo:APO_0000035 a rdfs:Class ;
  rdfs:label "nuclear fusion during mating" ;
  rdfs:comment "The fusion of the nuclei of two mating cells." ;
  rdfs:subClassOf obo:APO_0000032 .

obo:APO_0000215 a rdfs:Class ;
  rdfs:label "toxin resistance" ;
  rdfs:comment "The level of resistance to toxins, poisonous compounds that are produced by cells or organisms." ;
  rdfs:subClassOf obo:APO_0000080 .

obo:YPO_0000059 a rdfs:Class .

obo:APO_0000204 a rdfs:Class ;
  rdfs:label "hyperosmotic stress resistance" ;
  rdfs:comment "The level of resistance to high osmolarity." ;
  rdfs:subClassOf obo:APO_0000082 .

obo:APO_0000272 a rdfs:Class ;
  rdfs:label "Synthetic Haploinsufficiency" ;
  rdfs:subClassOf obo:APO_0000186 .

obo:APO_0000041 a rdfs:Class ;
  rdfs:label "sporulation" ;
  rdfs:comment "The formation of ascospores, which are the products of meiosis." ;
  rdfs:subClassOf obo:APO_0000031 .

obo:YPO_0000018 a rdfs:Class .

obo:APO_0000300 a rdfs:Class ;
  rdfs:label "endoplasmic reticulum distribution" ;
  rdfs:comment "The localization and placement of endoplasmic reticulum (ER) within a cell or between separating cells." ;
  rdfs:subClassOf obo:APO_0000296 .

obo:YPO_0000058 a rdfs:Class .

obo:APO_0000176 a rdfs:Class ;
  rdfs:label "Far Western" ;
  rdfs:subClassOf obo:APO_0000187 .

obo:YPO_0000007 a rdfs:Class .

obo:YPO_0000144 a rdfs:Class .

obo:APO_0000249 a rdfs:Class ;
  rdfs:label "delayed" ;
  rdfs:comment "Observed feature occurs after being postponed for a period of time relative to wild type." ;
  rdfs:subClassOf obo:APO_0000002 .

obo:APO_0000340 a rdfs:Class ;
  rdfs:label "reticulophagy" ;
  rdfs:comment "A form of macroautophagy selective for the endoplasmic reticulum that occurs in response to starvation, ER stress, aggregate accumulation or during a shift in environmental conditions." ;
  rdfs:subClassOf obo:APO_0000074 .

obo:APO_0000261 a rdfs:Class ;
  rdfs:label "cell cycle progression in early anaphase" ;
  rdfs:comment "Progression of cells through early anaphase during M phase of the mitotic cell cycle." ;
  rdfs:subClassOf obo:APO_0000260 .

obo:APO_0000073 a rdfs:Class ;
  rdfs:label "intracellular transport" ;
  rdfs:comment "Transport of substances within cells." ;
  rdfs:subClassOf obo:APO_0000066 .

obo:APO_0000234 a rdfs:Class ;
  rdfs:label "heterozygous diploid, competitive growth" ;
  rdfs:comment "Any competitive growth experiment carried out in a heterozygous diploid background." ;
  rdfs:subClassOf obo:APO_0000021 .

obo:APO_0000111 a rdfs:Class ;
  rdfs:label "viability" ;
  rdfs:comment "The proportion of cells in a sample that are viable, i.e. able to form colonies. Often measured by spotting aliquots of a dilution series on a plate." ;
  rdfs:subClassOf obo:APO_0000216 .

obo:APO_0000311 a rdfs:Class ;
  rdfs:label "growth in post-diauxic phase" ;
  rdfs:comment "Growth in liquid culture during the post-diauxic phase." ;
  rdfs:subClassOf obo:APO_0000106 .

obo:APO_0000342 a rdfs:Class ;
  rdfs:label "late nucleophagy" ;
  rdfs:comment "The autophagic degradation of bulk nucleoplasm that occurs after prolonged nitrogen starvation. In late nucleophagy, delivery of the nuclear cargo to the vacuole does not involve autophagosomes." ;
  rdfs:subClassOf obo:APO_0000074 .

obo:YPO_0000047 a rdfs:Class .

obo:APO_0000122 a rdfs:Class ;
  rdfs:label "cell cycle arrest in M phase" ;
  rdfs:comment "OBSOLETE. This term was not defined before being made obsolete." .

obo:YPO_0000256 a rdfs:Class .

obo:YPO_0000089 a rdfs:Class .

obo:YPO_0000149 a rdfs:Class .

obo:APO_0000104 a rdfs:Class ;
  rdfs:label "mitochondrial rho- mutation frequency" ;
  rdfs:comment "The frequency with rho- (rho minus) mutations occur, In this process, all of the mitochondrial genome except for a relatively short segment is lost. The retained segment is amplified and reiterated in a circular genome that is roughly the size of the wild-type genome." ;
  rdfs:subClassOf obo:APO_0000105 .

obo:APO_0000153 a rdfs:Class ;
  rdfs:label "petite" ;
  rdfs:comment "The formation of smaller than wild-type colonies on fermentable carbon sources (e.g., glucose), due to a respiratory defect. The respiratory defect could result from mutation or loss of the mitochondrial genome, or from a nuclear mutation affecting respiration. The fermentation of glucose produces ethanol, which is metabolized by the respiratory pathway in wild-type cells and contributes to colony size; respiratory-deficient mutants are unable to utilize this ethanol." ;
  rdfs:subClassOf obo:APO_0000102 .

obo:APO_0000062 a rdfs:Class ;
  rdfs:label "colony shape" ;
  rdfs:comment "The shape of colonies of cells growing on a solid substrate." ;
  rdfs:subClassOf obo:APO_0000060 .

obo:APO_0000280 a rdfs:Class ;
  rdfs:label "haploid, competitive growth" ;
  rdfs:comment "Any competitive growth experiment carried out in a haploid background." ;
  rdfs:subClassOf obo:APO_0000021 .

obo:APO_0000259 a rdfs:Class ;
  rdfs:label "cell cycle passage through the metaphase-anaphase transition" ;
  rdfs:comment "Progression of cells from metaphase to anaphase during M phase of the mitotic cell cycle." ;
  rdfs:subClassOf obo:APO_0000258 .

obo:APO_0000190 a rdfs:Class ;
  rdfs:label "Biochemical Assay" ;
  rdfs:subClassOf obo:APO_0000187 .

obo:APO_0000299 a rdfs:Class ;
  rdfs:label "vacuolar distribution" ;
  rdfs:comment "The localization and placement of vacuoles within a cell or between separating cells." ;
  rdfs:subClassOf obo:APO_0000296 .

obo:APO_0000046 a rdfs:Class ;
  rdfs:label "silencing" ;
  rdfs:comment "Repression of transcription by altering the structure of chromatin, e.g. by conversion of large regions of DNA into an inaccessible state often called heterochromatin." ;
  rdfs:subClassOf obo:APO_0000143 .

obo:APO_0000143 a rdfs:Class ;
  rdfs:label "chromosome/plasmid maintenance" ;
  rdfs:comment "The stable maintenance of chromosomes or plasmids." ;
  rdfs:subClassOf obo:APO_0000066 .

obo:APO_0000142 a rdfs:Class ;
  rdfs:label "critical cell size at G2/M (cryptic G2/M cell size checkpoint)" ;
  rdfs:comment "The cell volume (or size) which must be attained before cells can pass from G2 into M phase and commit to the completion of mitosis. This normally cryptic checkpoint negatively regulates passage from G2 into M phase." ;
  rdfs:subClassOf obo:APO_0000052 .

obo:YPO_0000278 a rdfs:Class .

obo:APO_0000288 a rdfs:Class ;
  rdfs:label "adhesion" ;
  rdfs:comment "Adherence to a substrate in the environment or in a host." ;
  rdfs:subClassOf obo:APO_0000287 .

obo:YPO_0000246 a rdfs:Class .

obo:YPO_0000198 a rdfs:Class .

obo:APO_0000294 a rdfs:Class ;
  rdfs:label "utilization of magnesium source" ;
  rdfs:comment "The ability to utilize the specified compound as a source of magnesium." ;
  rdfs:subClassOf obo:APO_0000096 .

obo:APO_0000007 a rdfs:Class ;
  rdfs:label "misexpression" ;
  rdfs:comment "The mutation results in expression of the gene product at a developmental stage, in a cell type, or at a subcellular location different from that at which the wild-type gene is expressed." ;
  rdfs:subClassOf obo:APO_0000006 .

obo:YPO_0000114 a rdfs:Class .

obo:APO_0000155 a rdfs:Class ;
  rdfs:label "apoptosis" ;
  rdfs:comment "An energy-dependent, programmed form of cell death that is characterized by phenotypic markers such as increased levels of reactive oxygen species (often detected via DHE staining), externalization of phosphatidylserine (measured by annexin V staining), and DNA fragmentation (detected using the TUNEL assay). Other processes observed during apoptosis include chromosome condensation and breakdown of mitochondria, including loss of membrane potential and release of cytochrome c. Cells undergoing apoptosis do not lose plasma membrane integrity (measured by propidium iodide staining) until late in the process." ;
  rdfs:subClassOf obo:APO_0000312 .

obo:YPO_0000045 a rdfs:Class .

obo:YPO_0000231 a rdfs:Class .

obo:YPO_0000209 a rdfs:Class .

obo:YPO_0000085 a rdfs:Class .

obo:APO_0000130 a rdfs:Class ;
  rdfs:label "small molecule transport" ;
  rdfs:comment "Transport of small molecules into, out of, or within the cell." ;
  rdfs:subClassOf obo:APO_0000073 .

obo:YPO_0000053 a rdfs:Class .

obo:YPO_0000013 a rdfs:Class .

obo:YPO_0000243 a rdfs:Class .

obo:APO_0000014 a rdfs:Class ;
  rdfs:label "conditional" ;
  rdfs:comment "The activity of the gene product is normal under some conditions and altered under others." ;
  rdfs:subClassOf obo:APO_0000006 .

obo:APO_0000208 a rdfs:Class ;
  rdfs:label "chromosome segregation" ;
  rdfs:comment "The physical separation of chromosomes and their distribution to two or more sets during mitosis or meiosis." ;
  rdfs:subClassOf obo:APO_0000143 .

obo:YPO_0000180 a rdfs:Class .

obo:YPO_0000252 a rdfs:Class .

obo:YPO_0000123 a rdfs:Class .

obo:APO_0000133 a rdfs:Class ;
  rdfs:label "cell cycle arrest in metaphase" ;
  rdfs:comment "OBSOLETE. This term was not defined before being made obsolete." .

obo:APO_0000148 a rdfs:Class ;
  rdfs:label "cold sensitivity" ;
  rdfs:comment "Sensitivity to temperatures that are lower than optimal growth temperature." ;
  rdfs:subClassOf obo:APO_0000092 .

obo:YPO_0000002 a rdfs:Class .

obo:APO_0000210 a rdfs:Class ;
  rdfs:label "anaerobic metabolism" ;
  rdfs:comment "Metabolism during growth in the absence of oxygen." ;
  rdfs:subClassOf obo:APO_0000094 .

obo:YPO_0000075 a rdfs:Class .

obo:YPO_0000194 a rdfs:Class .

obo:APO_0000224 a rdfs:Class ;
  rdfs:label "RNA accumulation" ;
  rdfs:comment "Abundance of a specified RNA or class of RNAs." ;
  rdfs:subClassOf obo:APO_0000094 .

obo:APO_0000187 a rdfs:Class ;
  rdfs:label "physical interactions" ;
  rdfs:subClassOf obo:APO_0000164 .

obo:YPO_0000009 a rdfs:Class .

obo:APO_0000108 a rdfs:Class ;
  rdfs:label "growth rate in post-diauxic phase" ;
  rdfs:comment "OBSOLETE: Growth rate in liquid culture during the post-diauxic phase." .

obo:YPO_0000113 a rdfs:Class .

obo:YPO_0000064 a rdfs:Class .

obo:APO_0000235 a rdfs:Class ;
  rdfs:label "systematic mutation set" ;
  rdfs:comment "Robotic generation and analysis of large-scale, genome-wide haploid knockout sets." ;
  rdfs:subClassOf obo:APO_0000114 .

obo:APO_0000051 a rdfs:Class ;
  rdfs:label "cell shape" ;
  rdfs:comment "The shape of the cell." ;
  rdfs:subClassOf obo:APO_0000050 .

obo:YPO_0000034 a rdfs:Class .

obo:YPO_0000129 a rdfs:Class .

obo:APO_0000120 a rdfs:Class ;
  rdfs:label "actin cytoskeleton morphology" ;
  rdfs:comment "The size, shape, or appearance of the actin cytoskeleton." ;
  rdfs:subClassOf obo:APO_0000054 .

obo:APO_0000246 a rdfs:Class ;
  rdfs:label "increased rate" ;
  rdfs:comment "Observed feature is increased with respect to time compared to that in the wild type (faster, accelerated)." ;
  rdfs:subClassOf obo:APO_0000002 .

obo:APO_0000174 a rdfs:Class ;
  rdfs:label "Epistatic MiniArray Profile" ;
  rdfs:subClassOf obo:APO_0000186 .

obo:YPO_0000172 a rdfs:Class .

obo:YPO_0000092 a rdfs:Class .

obo:YPO_0000012 a rdfs:Class .

obo:APO_0000159 a rdfs:Class ;
  rdfs:label "biofilm formation" ;
  rdfs:comment "The ability to form a layer on solid surfaces with or without other microorganisms." ;
  rdfs:subClassOf obo:APO_0000158 .

obo:APO_0000291 a rdfs:Class ;
  rdfs:label "formation of anatomical structure" ;
  rdfs:comment "The development of a discrete anatomical structure." ;
  rdfs:subClassOf obo:APO_0000023 .

obo:APO_0000305 a rdfs:Class ;
  rdfs:label "homozygous diploid, classical genetics" ;
  rdfs:comment "Any classical genetics experiment carried out in a homozygous diploid background." ;
  rdfs:subClassOf obo:APO_0000020 .

obo:APO_0000119 a rdfs:Class ;
  rdfs:label "size of nucleus" ;
  rdfs:comment "The size of the nucleus." ;
  rdfs:subClassOf obo:APO_0000057 .

obo:APO_0000198 a rdfs:Class ;
  rdfs:label "mutation frequency" ;
  rdfs:comment "The frequency with which mutations occur." ;
  rdfs:subClassOf obo:APO_0000143 .

obo:YPO_0000024 a rdfs:Class .

obo:YPO_0000159 a rdfs:Class .

obo:YPO_0000102 a rdfs:Class .

obo:YPO_0000191 a rdfs:Class .

obo:YPO_0000183 a rdfs:Class .

obo:YPO_0000023 a rdfs:Class .

obo:APO_0000256 a rdfs:Class ;
  rdfs:label "cell cycle passage through START" ;
  rdfs:comment "Passage of cells through cell cycle control point or checkpoint located late in the G1 phase of the mitotic cell cycle just prior to S phase entry; passage through START results in commits cells to progression through the entire cell cycle." ;
  rdfs:subClassOf obo:APO_0000255 .

obo:APO_0000166 a rdfs:Class ;
  rdfs:label "Biochemical Activity" ;
  rdfs:subClassOf obo:APO_0000187 .

obo:APO_0000327 a rdfs:Class ;
  rdfs:label "hydrostatic pressure resistance" ;
  rdfs:comment "The level of resistance to increased hydrostatic pressure." ;
  rdfs:subClassOf obo:APO_0000080 .

obo:YPO_0000270 a rdfs:Class .

obo:YPO_0000060 a rdfs:Class .

obo:YPO_0000035 a rdfs:Class .

obo:YPO_0000148 a rdfs:Class .

obo:APO_0000333 a rdfs:Class ;
  rdfs:label "acquired thermotolerance" ;
  rdfs:comment "The ability to survive a period of exposure to an acute heat shock after brief pretreatment at a mildly elevated temperature." ;
  rdfs:subClassOf obo:APO_0000093 .

obo:YPO_0000020 a rdfs:Class .

obo:APO_0000267 a rdfs:Class ;
  rdfs:label "entry into G0 (stationary phase)" ;
  rdfs:comment "Entry of cells into the G0 or stationary phase of the mitotic cell cycle, where they enter a quiescent state." ;
  rdfs:subClassOf obo:APO_0000072 .

obo:APO_0000079 a rdfs:Class ;
  rdfs:label "vacuolar transport" ;
  rdfs:comment "Transport of proteins into the vacuole." ;
  rdfs:subClassOf obo:APO_0000129 .

obo:YPO_0000213 a rdfs:Class .

obo:APO_0000338 a rdfs:Class ;
  rdfs:label "micronucleophagy" ;
  rdfs:comment "A form of microautophagy selective for the nucleus that occurs in response to starvation, damage or during a shift in environmental conditions." ;
  rdfs:subClassOf obo:APO_0000074 .

obo:YPO_0000220 a rdfs:Class .

obo:APO_0000316 a rdfs:Class ;
  rdfs:label "chronological lifespan" ;
  rdfs:comment "The number of days that a culture remains viable in stationary phase." ;
  rdfs:subClassOf obo:APO_0000030 .

obo:APO_0000242 a rdfs:Class ;
  rdfs:label "lipid particle morphology" ;
  rdfs:comment "The size, shape, or appearance of lipid particles or droplets, subcellular structures consisting of a hydrophobic core of neutral lipids (triacylglycerol and steryl esters), surrounded by a phospholipid monolayer with a small quantity of embedded proteins including enzymes involved in lipid biosynthesis. Lipid particles function as a storage compartment for lipid components." ;
  rdfs:subClassOf obo:APO_0000226 .

obo:APO_0000321 a rdfs:Class ;
  rdfs:label "phenotypic switching" ;
  rdfs:comment "The ability to undergo a reversible change from one distinct phenotype to another, resulting from changes in gene expression rather than from mutation. Cells in a specific phenotypic state have a distinct cellular morphology, which may be reflected in distinct colony morphology and different cellular properties, such as the ability to mate. A well-known example of phenotypic switching is the white-opaque switch of Candida albicans." ;
  rdfs:subClassOf obo:APO_0000023 .

obo:YPO_0000056 a rdfs:Class .

obo:YPO_0000249 a rdfs:Class .

obo:YPO_0000028 a rdfs:Class .

obo:YPO_0000202 a rdfs:Class .

obo:APO_0000315 a rdfs:Class ;
  rdfs:label "plasma membrane morphology" ;
  rdfs:comment "The size, shape, or appearance of the plasma membrane." ;
  rdfs:subClassOf obo:APO_0000226 .

obo:APO_0000309 a rdfs:Class ;
  rdfs:label "respiratory growth" ;
  rdfs:comment "Growth while utilizing a nonfermentable carbon source." ;
  rdfs:subClassOf obo:APO_0000102 .

obo:YPO_0000068 a rdfs:Class .

obo:APO_0000036 a rdfs:Class ;
  rdfs:label "pheromone production" ;
  rdfs:comment "The production of mating pheromones." ;
  rdfs:subClassOf obo:APO_0000032 .

obo:YPO_0000266 a rdfs:Class .

obo:APO_0000116 a rdfs:Class ;
  rdfs:label "other mutant type" ;
  rdfs:comment "OBSOLETE. This term was not defined before being made obsolete." .

obo:APO_0000304 a rdfs:Class ;
  rdfs:label "heterozygous diploid, classical genetics" ;
  rdfs:comment "Any classical genetics experiment carried out in a heterozygous diploid background." ;
  rdfs:subClassOf obo:APO_0000020 .

obo:APO_0000105 a rdfs:Class ;
  rdfs:label "mitochondrial genome maintenance" ;
  rdfs:comment "The maintenance of a stable and complete mitochondrial genome." ;
  rdfs:subClassOf obo:APO_0000102 .

obo:APO_0000278 a rdfs:Class ;
  rdfs:label "normal duration" ;
  rdfs:comment "Observed feature does not change with respect to time compared to that in the wild type." ;
  rdfs:subClassOf obo:APO_0000117 .

obo:APO_0000069 a rdfs:Class ;
  rdfs:label "cell cycle arrest at START" ;
  rdfs:comment "OBSOLETE. This term was not defined before being made obsolete." .

obo:APO_0000085 a rdfs:Class ;
  rdfs:label "UV resistance" ;
  rdfs:comment "The level of resistance to ultraviolet radiation." ;
  rdfs:subClassOf obo:APO_0000084 .

obo:APO_0000040 a rdfs:Class ;
  rdfs:label "meiotic recombination" ;
  rdfs:comment "The exchange of genetic material between non-sister chromatids in a pair of homologous chromosomes during meiosis." ;
  rdfs:subClassOf obo:APO_0000039 .

obo:YPO_0000067 a rdfs:Class .

obo:YPO_0000165 a rdfs:Class .

obo:APO_0000004 a rdfs:Class ;
  rdfs:label "increased" ;
  rdfs:comment "The observed feature is increased compared to that in the wild type (faster, stronger, higher, larger, etc.)." ;
  rdfs:subClassOf obo:APO_0000002 .

obo:APO_0000070 a rdfs:Class ;
  rdfs:label "cell cycle arrest" ;
  rdfs:comment "OBSOLETE. This term was not defined before being made obsolete." .

<http://purl.obolibrary.org/obo/apo#curators> a rdfs:Class .

obo:APO_0000197 a rdfs:Class ;
  rdfs:label "colony sectoring" ;
  rdfs:comment "Formation of wedge-shaped sectors, with a different color or appearance, in colonies of cells growing on a solid substrate." ;
  rdfs:subClassOf obo:APO_0000060 .

obo:APO_0000059 a rdfs:Class ;
  rdfs:label "vacuolar morphology" ;
  rdfs:comment "The size, shape, or appearance of the vacuole." ;
  rdfs:subClassOf obo:APO_0000303 .

obo:APO_0000152 a rdfs:Class ;
  rdfs:label "haploinsufficient" ;
  rdfs:comment "The heterozygous diploid displays a decreased growth rate relative to a diploid that is homozygous wild type at that locus." ;
  rdfs:subClassOf obo:APO_0000216 .

obo:YPO_0000039 a rdfs:Class .

obo:APO_0000186 a rdfs:Class ;
  rdfs:label "genetic interactions" ;
  rdfs:subClassOf obo:APO_0000164 .

obo:YPO_0000154 a rdfs:Class .

obo:APO_0000203 a rdfs:Class ;
  rdfs:label "hypoosmotic stress resistance" ;
  rdfs:comment "The level of resistance to low osmolarity." ;
  rdfs:subClassOf obo:APO_0000082 .

obo:APO_0000163 a rdfs:Class ;
  rdfs:label "Affinity Capture-RNA" ;
  rdfs:subClassOf obo:APO_0000187 .

obo:APO_0000123 a rdfs:Class ;
  rdfs:label "recovery from pheromone-induced cell cycle arrest" ;
  rdfs:comment "Resumption of the cell cycle after the arrest that occurs in response to the presence of mating pheromones from cells of the opposite mating type." ;
  rdfs:subClassOf obo:APO_0000037 .

obo:APO_0000332 a rdfs:Class ;
  rdfs:label "peg formation" ;
  rdfs:comment "Formation of a protrusion in a subapical hyphal cell that fuses with a clamp cell to form a fused clamp, in Basidiomycetes." ;
  rdfs:subClassOf obo:APO_0000291 .

obo:YPO_0000224 a rdfs:Class .

obo:APO_0000337 a rdfs:Class ;
  rdfs:label "polyploidy" ;
  rdfs:comment "The gain of an entire set or sets of chromosomes beyond the usual complement." ;
  rdfs:subClassOf obo:APO_0000143 .

obo:YPO_0000126 a rdfs:Class .

obo:APO_0000289 a rdfs:Class ;
  rdfs:label "response to light" ;
  rdfs:comment "The response to visible light." ;
  rdfs:subClassOf obo:APO_0000287 .

obo:APO_0000081 a rdfs:Class ;
  rdfs:label "killer toxin resistance" ;
  rdfs:comment "The level of resistance to killer toxin, which is encoded on double-stranded RNA viruses carried by some yeast strains." ;
  rdfs:subClassOf obo:APO_0000215 .

obo:YPO_0000235 a rdfs:Class .

obo:YPO_0000132 a rdfs:Class .

obo:YPO_0000208 a rdfs:Class .

obo:YPO_0000082 a rdfs:Class .

obo:APO_0000141 a rdfs:Class ;
  rdfs:label "critical cell size at START (G1 cell-size checkpoint)" ;
  rdfs:comment "The cell volume (or size) which must be attained before cells can pass through START, a checkpoint which operates in G1, and commit to a full round of cell division." ;
  rdfs:subClassOf obo:APO_0000052 .

obo:APO_0000112 a rdfs:Class ;
  rdfs:label "inviable" ;
  rdfs:comment "The inability to grow under standard growth conditions. For S. cerevisiae, this means that visible colonies are not formed from single cells on complete glucose medium (YPD) plates at 30 deg C under normal atmospheric conditions." ;
  rdfs:subClassOf obo:APO_0000217 .

obo:YPO_0000108 a rdfs:Class .

obo:APO_0000101 a rdfs:Class ;
  rdfs:label "fermentative metabolism" ;
  rdfs:comment "Growth with energy derived from fermentation; growth on a fermentable carbon source such as glucose." ;
  rdfs:subClassOf obo:APO_0000098 .

obo:APO_0000025 a rdfs:Class ;
  rdfs:label "axial budding pattern" ;
  rdfs:comment "Localization of the newly emerging bud near the site of the previous bud." ;
  rdfs:subClassOf obo:APO_0000200 .

obo:YPO_0000017 a rdfs:Class .

obo:YPO_0000057 a rdfs:Class .

obo:YPO_0000161 a rdfs:Class .

obo:YPO_0000262 a rdfs:Class .

obo:YPO_0000103 a rdfs:Class .

obo:YPO_0000230 a rdfs:Class .

obo:YPO_0000247 a rdfs:Class .

obo:APO_0000310 a rdfs:Class ;
  rdfs:label "growth in exponential phase" ;
  rdfs:comment "Growth in liquid culture during the exponential phase." ;
  rdfs:subClassOf obo:APO_0000106 .

obo:YPO_0000095 a rdfs:Class .

obo:YPO_0000042 a rdfs:Class .

obo:APO_0000095 a rdfs:Class ;
  rdfs:label "chemical compound accumulation" ;
  rdfs:comment "The production and/or storage of a specified chemical compound." ;
  rdfs:subClassOf obo:APO_0000094 .

obo:YPO_0000277 a rdfs:Class .

obo:APO_0000127 a rdfs:Class ;
  rdfs:label "nuclear export" ;
  rdfs:comment "Export of proteins or RNAs from the nucleus." ;
  rdfs:subClassOf obo:APO_0000077 .

obo:YPO_0000137 a rdfs:Class .

obo:YPO_0000255 a rdfs:Class .

obo:APO_0000144 a rdfs:Class ;
  rdfs:label "telomere length" ;
  rdfs:comment "The average length of telomeres." ;
  rdfs:subClassOf obo:APO_0000143 .

obo:YPO_0000088 a rdfs:Class .

obo:APO_0000193 a rdfs:Class ;
  rdfs:label "resistance to enzymatic treatment" ;
  rdfs:comment "The level of resistance to treatment with enzymes." ;
  rdfs:subClassOf obo:APO_0000080 .

obo:APO_0000182 a rdfs:Class ;
  rdfs:label "Synthetic Growth Defect" ;
  rdfs:subClassOf obo:APO_0000186 .

obo:APO_0000063 a rdfs:Class ;
  rdfs:label "colony size" ;
  rdfs:comment "The size of colonies of cells growing on a solid substrate." ;
  rdfs:subClassOf obo:APO_0000060 .

obo:YPO_0000119 a rdfs:Class .

obo:APO_0000137 a rdfs:Class ;
  rdfs:label "cell cycle arrest in mid anaphase" ;
  rdfs:comment "OBSOLETE. This term was not defined before being made obsolete." .

obo:YPO_0000078 a rdfs:Class .

obo:APO_0000191 a rdfs:Class ;
  rdfs:label "Purified Complex" ;
  rdfs:subClassOf obo:APO_0000187 .

obo:APO_0000047 a rdfs:Class ;
  rdfs:label "transposable element transposition" ;
  rdfs:comment "Integration of a transposable element  into new positions in the genome." ;
  rdfs:subClassOf obo:APO_0000143 .

obo:APO_0000177 a rdfs:Class ;
  rdfs:label "Phenotypic Enhancement" ;
  rdfs:subClassOf obo:APO_0000186 .

obo:YPO_0000006 a rdfs:Class .

obo:YPO_0000143 a rdfs:Class .

obo:APO_0000219 a rdfs:Class ;
  rdfs:label "utilization of sulfur source" ;
  rdfs:comment "The ability to utilize the specified compound as a source of sulfur." ;
  rdfs:subClassOf obo:APO_0000096 .

obo:YPO_0000219 a rdfs:Class .

obo:YPO_0000046 a rdfs:Class .

obo:APO_0000231 a rdfs:Class ;
  rdfs:label "homozygous diploid, large-scale survey" ;
  rdfs:comment "Any large-scale survey where the experiments are carried out in a homozygous diploid background." ;
  rdfs:subClassOf obo:APO_0000114 .

obo:APO_0000074 a rdfs:Class ;
  rdfs:label "autophagy" ;
  rdfs:comment "The delivery and degradation of autophagy markers to the vacuole via the autophagic pathway." ;
  rdfs:subClassOf obo:APO_0000073 .

obo:APO_0000214 a rdfs:Class ;
  rdfs:label "position of spindle pole body" ;
  rdfs:comment "The position of the mitotic or meiotic spindle pole body." ;
  rdfs:subClassOf obo:APO_0000213 .

obo:YPO_0000031 a rdfs:Class .

obo:APO_0000220 a rdfs:Class ;
  rdfs:label "necrotic cell death" ;
  rdfs:comment "A form of cell death that is distinct from apoptosis. Cells undergoing necrotic cell death undergo overall destruction. They can be distinguished from apoptotic cells because they lose membrane integrity, which only happens late in apoptosis (positive propidium iodide staining), and do not externalize phosphatidylserine (measured by annexin V staining) as do apoptotic cells." ;
  rdfs:subClassOf obo:APO_0000312 .

obo:YPO_0000071 a rdfs:Class .

obo:YPO_0000150 a rdfs:Class .

obo:APO_0000326 a rdfs:Class ;
  rdfs:label "desiccation resistance" ;
  rdfs:comment "The level of resistance to air-drying or desiccation stress." ;
  rdfs:subClassOf obo:APO_0000080 .

obo:IAO_0000115 a rdf:Property ;
  rdfs:label "definition" ;
  rdfs:range xsd:string .

obo:IAO_0100001 a rdf:Property ;
  rdfs:label "term replaced by" ;
  rdfs:range xsd:string .

<http://purl.obolibrary.org/obo/apo#AspGD> a rdf:Property ;
  rdfs:comment "APO terms in use at AspGD" ;
  rdfs:range xsd:string .

<http://purl.obolibrary.org/obo/apo#CGD> a rdf:Property ;
  rdfs:comment "APO terms in use at CGD" ;
  rdfs:range xsd:string .

<http://purl.obolibrary.org/obo/apo#CryptoGD> a rdf:Property ;
  rdfs:comment "APO terms in use at CryptoGD" ;
  rdfs:range xsd:string .

<http://purl.obolibrary.org/obo/apo#SGD> a rdf:Property ;
  rdfs:comment "APO terms in use at SGD" ;
  rdfs:range xsd:string .

<http://purl.obolibrary.org/obo/apo#phenotypeslim_cerevisiae> a rdf:Property ;
  rdfs:comment "Phenotype Slim terms for S. cerevisiae" ;
  rdfs:range xsd:string .
