PREFIX obo: <http://purl.obolibrary.org/obo/>
PREFIX rdf: <http://www.w3.org/1999/02/22-rdf-syntax-ns#>
PREFIX rdfs: <http://www.w3.org/2000/01/rdf-schema#>
PREFIX xsd: <http://www.w3.org/2001/XMLSchema#>

obo:NCBITaxon_117571 a rdfs:Class ;
  rdfs:label "Euteleostomi" ;
  rdfs:subClassOf obo:NCBITaxon_7742 .

obo:RO_0002450 a rdf:Property ;
  rdfs:label "directly positively regulates activity of" ;
  rdfs:comment """The entity A, immediately upstream of the entity B, has an activity that positively regulates an activity performed by B. 
For example, A and B may be gene products and binding of B by A positively regulates the kinase activity of B.""" ;
  rdfs:domain obo:BFO_0000040 ;
  rdfs:range obo:BFO_0000040 ;
  rdfs:subPropertyOf obo:RO_0002448 .

obo:RO_0002449 a rdf:Property ;
  rdfs:label "directly negatively regulates activity of" ;
  rdfs:comment """The entity A, immediately upstream of the entity B, has an activity that negatively regulates an activity performed by B. 
For example, A and B may be gene products and binding of B by A negatively regulates the kinase activity of B.""" ;
  rdfs:domain obo:BFO_0000040 ;
  rdfs:range obo:BFO_0000040 ;
  rdfs:subPropertyOf obo:RO_0002448 .

obo:RO_0001000 a rdf:Property ;
  rdfs:label "derives from"@en ;
  rdfs:comment "a relation between two distinct material entities, the new entity and the old entity, in which the new entity begins to exist when the old entity ceases to exist, and the new entity inherits the significant portion of the matter of the old entity"@en ;
  rdfs:domain obo:BFO_0000004 ;
  rdfs:range obo:BFO_0000004 .

obo:RO_0002448 a rdf:Property ;
  rdfs:label "directly regulates activity of" ;
  rdfs:comment """The entity A, immediately upstream of the entity B, has an activity that regulates an activity performed by B. For example, A and B may be gene products and binding of B by A regulates the kinase activity of B.

A and B can be physically interacting but not necessarily. Immediately upstream means there are no intermediate entity between A and B.""" ;
  rdfs:domain obo:BFO_0000040 ;
  rdfs:range obo:BFO_0000040 ;
  rdfs:subPropertyOf obo:RO_0011002 , obo:RO_0002436 .

obo:RO_0002506 a rdf:Property ;
  rdfs:label "causal relation between entities" ;
  rdfs:domain obo:BFO_0000002 ;
  rdfs:range obo:BFO_0000002 ;
  rdfs:subPropertyOf obo:RO_0002410 .

obo:RO_0011002 a rdf:Property ;
  rdfs:label "regulates activity of" ;
  rdfs:comment "The entity A has an activity that regulates an activity of the entity B. For example, A and B are gene products where the catalytic activity of A regulates the kinase activity of B." ;
  rdfs:domain obo:BFO_0000040 ;
  rdfs:range obo:BFO_0000040 ;
  rdfs:subPropertyOf obo:RO_0002566 .

obo:RO_0002566 a rdf:Property ;
  rdfs:label "causally influences" ;
  rdfs:comment "The entity or characteristic A is causally upstream of the entity or characteristic B, A having an effect on B. An entity corresponds to any biological type of entity as long as a mass is measurable. A characteristic corresponds to a particular specificity of an entity (e.g., phenotype, shape, size)." ;
  rdfs:domain obo:BFO_0000002 ;
  rdfs:range obo:BFO_0000002 ;
  rdfs:subPropertyOf obo:RO_0002506 .

obo:RO_0000087 a rdf:Property ;
  rdfs:label "has role"@en ;
  rdfs:comment "a relation between an independent continuant (the bearer) and a role, in which the role specifically depends on the bearer for its existence"@en ;
  rdfs:domain obo:BFO_0000004 ;
  rdfs:range obo:BFO_0000023 ;
  rdfs:subPropertyOf obo:RO_0000053 .

obo:RO_0002215 a rdf:Property ;
  rdfs:label "capable of"@en ;
  rdfs:comment "A relation between a material entity (such as a cell) and a process, in which the material entity has the ability to carry out the process." ;
  rdfs:domain obo:BFO_0000004 ;
  rdfs:range obo:BFO_0000015 ;
  rdfs:subPropertyOf obo:RO_0002216 .

obo:RO_0000085 a rdf:Property ;
  rdfs:label "has function"@en ;
  rdfs:comment "a relation between an independent continuant (the bearer) and a function, in which the function specifically depends on the bearer for its existence"@en ;
  rdfs:domain obo:BFO_0000004 ;
  rdfs:range obo:BFO_0000034 ;
  rdfs:subPropertyOf obo:RO_0000053 .

obo:RO_0002595 a rdf:Property ;
  rdfs:label "causal relation between material entity and a process" ;
  rdfs:comment "A relationship that holds between a material entity and a process in which causality is involved, with either the material entity or some part of the material entity exerting some influence over the process, or the process influencing some aspect of the material entity." ;
  rdfs:domain obo:BFO_0000040 ;
  rdfs:range obo:BFO_0000015 ;
  rdfs:subPropertyOf obo:RO_0002410 .

obo:BFO_0000050 a rdf:Property ;
  rdfs:label "part of"@en ;
  rdfs:comment "a core relation that holds between a part and its whole"@en ;
  rdfs:seeAlso <http://ontologydesignpatterns.org/wiki/Community:Parts_and_Collections> , <http://ontologydesignpatterns.org/wiki/Submissions:PartOf> , <http://www.obofoundry.org/ro/#OBO_REL:part_of> ;
  rdfs:range obo:BFO_0000004 , obo:BFO_0000003 , obo:BFO_0000002 , obo:BFO_0000017 , obo:BFO_0000019 , obo:BFO_0000020 ;
  rdfs:subPropertyOf obo:RO_0002131 .

obo:RO_0000091 a rdf:Property ;
  rdfs:label "has disposition"@en ;
  rdfs:comment "a relation between an independent continuant (the bearer) and a disposition, in which the disposition specifically depends on the bearer for its existence"@en ;
  rdfs:domain obo:BFO_0000004 ;
  rdfs:range obo:BFO_0000016 ;
  rdfs:subPropertyOf obo:RO_0000053 .

obo:RO_0000056 a rdf:Property ;
  rdfs:label "participates in"@en ;
  rdfs:comment "a relation between a continuant and a process, in which the continuant is somehow involved in the process"@en ;
  rdfs:domain obo:BFO_0000002 ;
  rdfs:range obo:BFO_0000003 .

obo:RO_0002434 a rdf:Property ;
  rdfs:label "interacts with" ;
  rdfs:comment "A relationship that holds between two entities in which the processes executed by the two entities are causally connected." ;
  rdfs:seeAlso <http://purl.obolibrary.org/obo/ro/docs/interaction-relations/> ;
  rdfs:domain obo:BFO_0000040 ;
  rdfs:range obo:BFO_0000040 .

obo:OBI_0000094 a rdfs:Class ;
  rdfs:label "material processing"@en ;
  rdfs:comment "A planned process which results in physical changes in a specified input material"@en ;
  rdfs:subClassOf obo:OBI_0000011 .

obo:BFO_0000062 a rdf:Property ;
  rdfs:label "preceded by"@en ;
  rdfs:comment "x is preceded by y if and only if the time point at which y ends is before or equivalent to the time point at which x starts. Formally: x preceded by y iff ω(y) <= α(x), where α is a function that maps a process to a start point, and ω is a function that maps a process to an end point."@en ;
  rdfs:domain obo:BFO_0000003 ;
  rdfs:range obo:BFO_0000003 ;
  rdfs:subPropertyOf obo:RO_0002086 .

obo:BFO_0000063 a rdf:Property ;
  rdfs:label "precedes"@en ;
  rdfs:comment "x precedes y if and only if the time point at which x ends is before or equivalent to the time point at which y starts. Formally: x precedes y iff ω(x) <= α(y), where α is a function that maps a process to a start point, and ω is a function that maps a process to an end point."@en ;
  rdfs:domain obo:BFO_0000003 ;
  rdfs:range obo:BFO_0000003 ;
  rdfs:subPropertyOf obo:RO_0002222 .

obo:RO_0002501 a rdf:Property ;
  rdfs:label "causal relation between processes" ;
  rdfs:comment "p is causally related to q if and only if p or any part of p and q or any part of q are linked by a chain of events where each event pair is one where the execution of p influences the execution of q. p may be upstream, downstream, part of, or a container of q." ;
  rdfs:domain obo:BFO_0000003 ;
  rdfs:range obo:BFO_0000003 ;
  rdfs:subPropertyOf obo:RO_0002410 .

obo:RO_0019000 a rdf:Property ;
  rdfs:label "regulates characteristic" ;
  rdfs:comment "A relationship that holds between a process and a characteristic in which process (P) regulates characteristic (C) iff: P results in the existence of C OR affects the intensity or magnitude of C." ;
  rdfs:domain obo:BFO_0000015 ;
  rdfs:range obo:PATO_0000001 ;
  rdfs:subPropertyOf obo:RO_0002410 .

obo:OBI_0000417 a rdf:Property ;
  rdfs:label "achieves_planned_objective" ;
  rdfs:comment "This relation obtains between a planned process and a objective specification when the criteria specified in the objective specification are met at the end of the planned process." ;
  rdfs:domain obo:OBI_0000011 ;
  rdfs:range obo:IAO_0000005 .

obo:RO_0002233 a rdf:Property ;
  rdfs:label "has input"@en ;
  rdfs:comment "p has input c iff: p is a process, c is a material entity, c is a participant in p, c is present at the start of p, and the state of c is modified during p." ;
  rdfs:domain obo:BFO_0000015 ;
  rdfs:range obo:BFO_0000002 ;
  rdfs:subPropertyOf obo:RO_0000057 .

obo:RO_0002211 a rdf:Property ;
  rdfs:label "regulates"@en ;
  rdfs:comment "p regulates q iff p is causally upstream of q, the execution of p is not constant and varies according to specific conditions, and p influences the rate or magnitude of execution of q due to an effect either on some enabler of q or some enabler of a part of q." ;
  rdfs:domain obo:BFO_0000015 ;
  rdfs:range obo:BFO_0000015 ;
  rdfs:subPropertyOf obo:RO_0002411 .

obo:OBI_0000293 a rdf:Property ;
  rdfs:label "has_specified_input"@en ;
  rdfs:comment "The inverse property of is_specified_input_of"@en ;
  rdfs:domain obo:OBI_0000011 ;
  rdfs:range obo:BFO_0000040 , obo:IAO_0000027 , obo:BFO_0000002 , obo:OBI_0000648 ;
  rdfs:subPropertyOf obo:RO_0000057 .

obo:RO_0002018 a rdf:Property ;
  rdfs:label "has component process" ;
  rdfs:comment "w 'has process component' p if p and w are processes,  w 'has part' p and w is such that it can be directly disassembled into into n parts p, p2, p3, ..., pn, where these parts are of similar type." ;
  rdfs:domain obo:BFO_0000015 ;
  rdfs:range obo:BFO_0000015 ;
  rdfs:subPropertyOf obo:RO_0002180 .

obo:OBI_0000299 a rdf:Property ;
  rdfs:label "has_specified_output"@en ;
  rdfs:comment "The inverse property of is_specified_output_of"@en ;
  rdfs:domain obo:OBI_0000011 ;
  rdfs:range obo:BFO_0000002 ;
  rdfs:subPropertyOf obo:RO_0000057 .

obo:BFO_0000055 a rdf:Property ;
  rdfs:label "realizes"@en ;
  rdfs:comment "Paraphrase of elucidation: a relation between a process and a realizable entity, where there is some material entity that is bearer of the realizable entity and participates in the process, and the realizable entity comes to be realized in the course of the process" ;
  rdfs:domain obo:BFO_0000015 ;
  rdfs:range obo:BFO_0000017 .

obo:RO_0000057 a rdf:Property ;
  rdfs:label "has participant"@en ;
  rdfs:comment "a relation between a process and a continuant, in which the continuant is somehow involved in the process"@en ;
  rdfs:domain obo:BFO_0000003 ;
  rdfs:range obo:BFO_0000002 .

obo:RO_0002222 a rdf:Property ;
  rdfs:label "temporally related to"@en ;
  rdfs:comment "A relation that holds between two occurrents. This is a grouping relation that collects together all the Allen relations." ;
  rdfs:domain obo:BFO_0000003 ;
  rdfs:range obo:BFO_0000003 .

obo:RO_0002334 a rdf:Property ;
  rdfs:label "regulated by"@en ;
  rdfs:comment "inverse of regulates" ;
  rdfs:domain obo:BFO_0000015 ;
  rdfs:range obo:BFO_0000015 ;
  rdfs:subPropertyOf obo:RO_0002427 .

obo:SDDO_1000002 a rdfs:Class ;
  rdfs:label "spase:DisplayData"@en ;
  rdfs:comment "A graphical representation of data wherein the underlying numeric values are not (readily) accessible for analysis." ;
  rdfs:subClassOf obo:SDDO_3000051 .

obo:OBI_0000312 a rdf:Property ;
  rdfs:label "is_specified_output_of"@en ;
  rdfs:comment "A relation between a planned process and a continuant participating in that process. The presence of the continuant at the end of the process is explicitly specified in the objective specification which the process realizes the concretization of."@en ;
  rdfs:domain obo:BFO_0000002 ;
  rdfs:range obo:OBI_0000011 ;
  rdfs:subPropertyOf obo:RO_0000056 .

obo:RO_0000058 a rdf:Property ;
  rdfs:label "is concretized as"@en ;
  rdfs:comment "A relationship between a generically dependent continuant and a specifically dependent continuant, in which the generically dependent continuant depends on some independent continuant in virtue of the fact that the specifically dependent continuant also depends on that same independent continuant. A generically dependent continuant may be concretized as multiple specifically dependent continuants."@en ;
  rdfs:domain obo:BFO_0000031 ;
  rdfs:range obo:BFO_0000020 .

obo:IAO_0000136 a rdf:Property ;
  rdfs:label "is about"@en ;
  rdfs:comment "A (currently) primitive relation that relates an information artifact to an entity."@en ;
  rdfs:domain obo:IAO_0000030 ;
  rdfs:range <https://w3id.org/linkml/Any> .

obo:BFO_0000034 a rdfs:Class ;
  rdfs:label "function"@en ;
  rdfs:subClassOf obo:BFO_0000016 .

obo:RO_0000059 a rdf:Property ;
  rdfs:label "concretizes"@en ;
  rdfs:comment "A relationship between a specifically dependent continuant and a generically dependent continuant, in which the generically dependent continuant depends on some independent continuant in virtue of the fact that the specifically dependent continuant also depends on that same independent continuant. Multiple specifically dependent continuants can concretize the same generically dependent continuant."@en ;
  rdfs:domain obo:BFO_0000020 ;
  rdfs:range obo:BFO_0000031 .

obo:BFO_0000054 a rdf:Property ;
  rdfs:label "realized in"@en ;
  rdfs:comment "Paraphrase of elucidation: a relation between a realizable entity and a process, where there is some material entity that is bearer of the realizable entity and participates in the process, and the realizable entity comes to be realized in the course of the process" ;
  rdfs:domain obo:BFO_0000017 ;
  rdfs:range obo:BFO_0000015 , obo:OBI_0000011 , obo:OBI_0000457 , obo:OBI_0000066 .

obo:RO_0000079 a rdf:Property ;
  rdfs:label "function of"@en ;
  rdfs:comment "a relation between a function and an independent continuant (the bearer), in which the function specifically depends on the bearer for its existence"@en ;
  rdfs:domain obo:BFO_0000034 ;
  rdfs:range <https://w3id.org/linkml/Any> ;
  rdfs:subPropertyOf obo:RO_0000052 .

obo:UBERON_0000465 a rdfs:Class ;
  rdfs:label "material anatomical entity" ;
  rdfs:comment "Anatomical entity that has mass." ;
  rdfs:subClassOf obo:BFO_0000040 .

obo:SDDO_3000095 a rdfs:Class ;
  rdfs:label "metadata product"@en ;
  rdfs:comment "An information product that contains structured metadata." ;
  rdfs:subClassOf obo:SDDO_3000079 .

obo:IAO_0000009 a rdfs:Class ;
  rdfs:label "datum label"@en ;
  rdfs:comment "A label is a symbol that is part of some other datum and is used to either partially define  the denotation of that datum or to provide a means for identifying the datum as a member of the set of data with the same label"@en ;
  rdfs:subClassOf obo:IAO_0000030 .

obo:OBI_0000947 a rdfs:Class ;
  rdfs:label "service provider role" ;
  rdfs:comment "is a role which inheres in a person or organization and is realized in in a planned process which provides access to training, materials or execution of protocols for an organization or person" ;
  rdfs:subClassOf obo:BFO_0000023 .

obo:BFO_0000017 a rdfs:Class ;
  rdfs:label "realizable entity"@en ;
  rdfs:comment "A specifically dependent continuant  that inheres in continuant  entities and are not exhibited in full at every time in which it inheres in an entity or group of entities. The exhibition or actualization of a realizable entity is a particular manifestation, functioning or process that occurs under certain circumstances."@en ;
  rdfs:subClassOf obo:BFO_0000020 .

obo:OBI_0200172 a rdfs:Class ;
  rdfs:label "partitioning objective"@en ;
  rdfs:comment "A partitioning objective is a data transformation objective where the aim is to generate a collection of disjoint non-empty subsets whose union equals a non-empty input set."@en ;
  rdfs:subClassOf obo:OBI_0200166 .

obo:OBI_0000833 a rdf:Property ;
  rdfs:label "objective_achieved_by" ;
  rdfs:comment "This relation obtains between an objective specification and a planned process when the criteria specified in the objective specification are met at the end of the planned process." ;
  rdfs:domain obo:IAO_0000005 ;
  rdfs:range obo:OBI_0000011 .

obo:SDDO_3000079 a rdfs:Class ;
  rdfs:label "information product"@en ;
  rdfs:comment "A product that describes some entity." ;
  rdfs:subClassOf obo:SDDO_3000066 .

obo:OBI_0000663 a rdfs:Class ;
  rdfs:label "class prediction data transformation"@en ;
  rdfs:comment "A class prediction data transformation (sometimes called supervised classification) is a data transformation that has objective class prediction."@en ;
  rdfs:subClassOf obo:OBI_0200000 .

obo:OBI_0200042 a rdfs:Class ;
  rdfs:label "hierarchical clustering"@en ;
  rdfs:comment "A hierarchical clustering is a data transformation which achieves a class discovery objective, which takes as input data item and builds a hierarchy of clusters. The traditional representation of this hierarchy is a tree (visualized by a dendrogram), with the individual input objects at one end (leaves) and a single cluster containing every object at the other (root)."@en ;
  rdfs:subClassOf obo:APOLLO_SV_00000796 , obo:OBI_0200175 .

<http://www.ebi.ac.uk/swo/SWO_0000002> a rdfs:Class ;
  rdfs:label "software license" ;
  rdfs:comment "A licence is a legal instrument (usually by way of contract law, with or without printed material) governing the use or redistribution of the resource containing the licence." ;
  rdfs:subClassOf obo:IAO_0000030 .

obo:OBI_0001933 a rdfs:Class ;
  rdfs:label "value specification" ;
  rdfs:comment "An information content entity that specifies a value within a classification scheme or on a quantitative scale." ;
  rdfs:subClassOf obo:IAO_0000030 .

obo:SDDO_3000084 a rdfs:Class ;
  rdfs:label "software"@en ;
  rdfs:comment "An information content entity that 1) contains a set of machine-readable instructions (most often in the form of a computer program) that 2) conform to a given syntax (sometimes referred to as a language) that 3) is interpretable by a given processor and that 4) directs a computer's processor to perform specific operations." ;
  rdfs:subClassOf <http://www.ebi.ac.uk/swo/SWO_0000001> .

obo:OBI_0000792 a rdfs:Class ;
  rdfs:label "statistical model validation" ;
  rdfs:comment "A data transformation which assesses how the results of a statistical analysis will generalize to an independent data set." ;
  rdfs:subClassOf obo:OBI_0200171 .

obo:IAO_0000183 a rdfs:Class ;
  rdfs:label "dendrogram"@en ;
  rdfs:comment """A dendrogram is a report graph which is a tree diagram
frequently used to illustrate the arrangement of the clusters produced by a
clustering algorithm."""@en ;
  rdfs:subClassOf obo:IAO_0000038 .

obo:OBI_0500000 a rdfs:Class ;
  rdfs:label "study design"@en ;
  rdfs:comment "A plan specification comprised of protocols (which may specify how and what kinds of data will be gathered) that are executed as part of an investigation and is realized during a study design execution." ;
  rdfs:subClassOf obo:IAO_0000104 .

obo:BFO_0000051 a rdf:Property ;
  rdfs:label "has part"@en ;
  rdfs:comment "a core relation that holds between a whole and its part"@en ;
  rdfs:range <https://w3id.org/linkml/Any> ;
  rdfs:subPropertyOf obo:RO_0002131 .

obo:SDDO_3000047 a rdfs:Class ;
  rdfs:label "assay"@en ;
  rdfs:comment "An assay is an investigative (analytic) procedure for qualitatively assessing or quantitatively measuring the presence, amount, or functional activity of a target entity." .

obo:SDDO_3000017 a rdf:Property ;
  rdfs:label "createdBy"@en ;
  rdfs:range <https://w3id.org/linkml/Any> .

obo:SDDO_3000024 a rdf:Property ;
  rdfs:label "capableOfIdentifying"@en ;
  rdfs:range <https://w3id.org/linkml/Any> .

obo:SDDO_3000026 a rdf:Property ;
  rdfs:label "capableOfDetecting"@en ;
  rdfs:range <https://w3id.org/linkml/Any> .

obo:NCBITaxon_314146 a rdfs:Class ;
  rdfs:label "Euarchontoglires" ;
  rdfs:subClassOf obo:NCBITaxon_40674 .

obo:OBI_0000457 a rdfs:Class ;
  rdfs:label "manufacturing"@en ;
  rdfs:comment "Manufacturing is a process with the intent to produce a processed material which will have a function for future use. A person or organization (having manufacturer role) is a participant in this process"@en ;
  rdfs:subClassOf obo:OBI_0000094 .

obo:OBI_0000047 a rdfs:Class ;
  rdfs:label "processed material"@en ;
  rdfs:comment "Is a material entity that is created or changed during material processing."@en ;
  rdfs:subClassOf obo:BFO_0000040 .

obo:OBI_0000835 a rdfs:Class ;
  rdfs:label "manufacturer" ;
  rdfs:comment "A person or organization that has a manufacturer role" ;
  rdfs:subClassOf obo:BFO_0000040 .

obo:OBI_0000023 a rdfs:Class ;
  rdfs:label "classified data set"@en ;
  rdfs:comment "A data set that is produced as the output of a class prediction data transformation and consists of a data set with assigned class labels."@en ;
  rdfs:subClassOf obo:IAO_0000100 .

obo:GO_0016740 a rdfs:Class ;
  rdfs:label "transferase activity" ;
  rdfs:subClassOf obo:GO_0003824 .

obo:OBI_0000968 a rdfs:Class ;
  rdfs:label "device" ;
  rdfs:comment "A material entity that is designed to perform a function in a scientific investigation, but is not a reagent." ;
  rdfs:subClassOf obo:OBI_0000047 .

obo:NCBITaxon_33208 a rdfs:Class ;
  rdfs:label "Metazoa" ;
  rdfs:subClassOf obo:NCBITaxon_33154 .

obo:OBI_0000684 a rdfs:Class ;
  rdfs:label "specimen collection objective" ;
  rdfs:comment "A objective specification to obtain a material entity for potential use as an input during an investigation." ;
  rdfs:subClassOf obo:IAO_0000005 .

obo:SDDO_1000009 a rdfs:Class ;
  rdfs:label "discovery interface"@en ;
  rdfs:comment "An interface that 1) presents users with discovery criteria and may 2) lead to an access interface." ;
  rdfs:subClassOf <http://www.ebi.ac.uk/swo/SWO_9000050> .

obo:IAO_0000178 a rdfs:Class ;
  rdfs:label "material information bearer"@en ;
  rdfs:comment "A material entity in which a concretization of an information content entity inheres."@en ;
  rdfs:subClassOf obo:BFO_0000040 .

<http://www.w3.org/2003/11/swrl#Variable> a rdfs:Class .

obo:SDDO_1000010 a rdfs:Class ;
  rdfs:label "field campaign"@en ;
  rdfs:comment "A campaign that is coordinated among one or more individuals and/or one or more organizations." ;
  rdfs:subClassOf obo:SDDO_3000045 .

obo:SDDO_3000009 a rdf:Property ;
  rdfs:label "uses"@en ;
  rdfs:range <https://w3id.org/linkml/Any> .

obo:SDDO_3000020 a rdf:Property ;
  rdfs:label "resultsIn"@en ;
  rdfs:range <https://w3id.org/linkml/Any> .

obo:OBI_0000450 a rdfs:Class ;
  rdfs:label "regulatory agency"@en ;
  rdfs:comment "A regulatory agency is a organization that has responsibility over or for  the legislation (acts and regulations) for a given sector of the government."@en ;
  rdfs:subClassOf obo:OBI_0000245 .

obo:IAO_0000308 a rdfs:Class ;
  rdfs:label "figure"@en ;
  rdfs:comment "An information content entity consisting of a two dimensional arrangement of information content entities such that the arrangement itself is about something."@en ;
  rdfs:subClassOf obo:IAO_0000030 .

obo:OBI_0002356 a rdfs:Class ;
  rdfs:label "performance status value specification" ;
  rdfs:comment "A categorical value specification that is an assessment of a participant's performance status (general well-being and activities of daily life)." ;
  rdfs:subClassOf obo:OBI_0001930 .

obo:BFO_0000040 a rdfs:Class ;
  rdfs:label "material entity" ;
  rdfs:comment "An independent continuant [snap:IndependentContinuant] that is spatially extended whose identity is independent of that of other entities and can be maintained through time. Note: Material entity [snap:MaterialEntity] subsumes object [snap:Object], fiat object part [snap:FiatObjectPart], and object aggregate [snap:ObjectAggregate], which assume a three level theory of granularity, which is inadequate for some domains, such as biology." ;
  rdfs:subClassOf obo:BFO_0000004 .

obo:SDDO_3000100 a rdfs:Class ;
  rdfs:label "observation"@en ;
  rdfs:comment "Act of carrying out an procedure to estimate or calculate a value of a property of a feature." ;
  rdfs:subClassOf obo:OBI_0000011 , <http://www.w3.org/ns/sosa/Observation> .

obo:SDDO_3000105 a rdfs:Class ;
  rdfs:label "investigator"@en ;
  rdfs:comment "A role which inheres in a person or organization and which is realized during an investigation." ;
  rdfs:subClassOf obo:BFO_0000023 .

<http://www.w3.org/ns/sosa/Platform> a rdfs:Class ;
  rdfs:label "Platform"@en ;
  rdfs:comment "A Platform is an entity that hosts other entities, particularly Sensors, Actuators, Samplers, and other Platforms."@en .

obo:NCBITaxon_2157 a rdfs:Class ;
  rdfs:label "Archaea" ;
  rdfs:subClassOf obo:OBI_0100026 .

obo:OBI_0200171 a rdfs:Class ;
  rdfs:label "partitioning data transformation"@en ;
  rdfs:comment "A partitioning data transformation is a data transformation that has objective partitioning."@en ;
  rdfs:subClassOf obo:OBI_0200000 .

obo:GO_0016772 a rdfs:Class ;
  rdfs:label "transferase activity, transferring phosphorus-containing groups" ;
  rdfs:subClassOf obo:GO_0016740 .

obo:SDDO_3000109 a rdfs:Class ;
  rdfs:label "document"@en ;
  rdfs:comment "A written or printed paper that bears the original, official, or legal form of something and can be used to furnish decisive evidence or information." ;
  rdfs:subClassOf obo:IAO_0000310 , obo:SDDO_3000079 .

obo:SDDO_3000094 a rdfs:Class ;
  rdfs:label "experiment"@en ;
  rdfs:comment "A plan for a coordinated set of actions and observations designed to generate data, with the ultimate goal of discovery or hypothesis testing." ;
  rdfs:subClassOf obo:OBI_0000011 .

obo:SDDO_3000042 a rdf:Property ;
  rdfs:label "partOf"@en ;
  rdfs:range <https://w3id.org/linkml/Any> .

obo:SDDO_3000008 a rdf:Property ;
  rdfs:label "generates"@en ;
  rdfs:range <https://w3id.org/linkml/Any> .

obo:SDDO_3000036 a rdf:Property ;
  rdfs:label "conductedOn"@en ;
  rdfs:range <https://w3id.org/linkml/Any> .

obo:SDDO_3000023 a rdf:Property ;
  rdfs:label "conductedAt"@en ;
  rdfs:range <https://w3id.org/linkml/Any> .

obo:SDDO_3000013 a rdf:Property ;
  rdfs:label "componentOf"@en ;
  rdfs:range <https://w3id.org/linkml/Any> .

obo:IAO_0000100 a rdfs:Class ;
  rdfs:label "data set"@en ;
  rdfs:comment "A data item that is an aggregate of other data items of the same type that have something in common. Averages and distributions can be determined for data sets."@en ;
  rdfs:subClassOf obo:IAO_0000027 .

obo:IAO_0000572 a rdfs:Class ;
  rdfs:label "documenting"@en ;
  rdfs:comment "A planned process in which a document is created or added to by including the specified input in it."@en ;
  rdfs:subClassOf obo:OBI_0000011 .

obo:BFO_0000023 a rdfs:Class ;
  rdfs:label "role"@en ;
  rdfs:comment "A realizable entity  the manifestation of which brings about some result or end that is not essential to a continuant  in virtue of the kind of thing that it is but that can be served or participated in by that kind of continuant  in some kinds of natural, social or institutional contexts."@en ;
  rdfs:subClassOf obo:BFO_0000017 .

obo:SDDO_3000044 a rdfs:Class ;
  rdfs:label "event"@en ;
  rdfs:comment "Something observable that happened at a given time and place" ;
  rdfs:subClassOf obo:BFO_0000015 , obo:SDDO_3000099 .

obo:IAO_0000309 a rdfs:Class ;
  rdfs:label "diagram"@en ;
  rdfs:comment "A figure that expresses one or more propositions"@en ;
  rdfs:subClassOf obo:IAO_0000308 .

<http://www.ebi.ac.uk/swo/SWO_0000001> a rdfs:Class ;
  rdfs:label "software" ;
  rdfs:comment "Computer software, or generally just software, is any set of machine-readable instructions (most often in the form of a computer program) that conform to a given syntax (sometimes referred to as a language) that is interpretable by a given processor and that directs a computer's processor to perform specific operations." ;
  rdfs:subClassOf obo:IAO_0000033 .

obo:GO_0008150 a rdfs:Class ;
  rdfs:label "biological_process" ;
  rdfs:subClassOf obo:BFO_0000015 .

<http://www.ebi.ac.uk/swo/interface/SWO_9000054> a rdfs:Class ;
  rdfs:label "application programming interface" ;
  rdfs:comment "An application programming interface is a set of routines, protocols, and tools for building software applications. An API expresses a software component in terms of its operations, inputs, outputs, and underlying types. An API defines functionalities that are independent of their respective implementations, which allows definitions and implementations to vary without compromising each other. The API specifies how software components should interact." ;
  rdfs:subClassOf <http://www.ebi.ac.uk/swo/SWO_9000050> .

obo:SDDO_3000099 a rdfs:Class ;
  rdfs:label "phenomenon"@en ;
  rdfs:comment "A fact or situation that is observed to exist." .

obo:GO_0003674 a rdfs:Class ;
  rdfs:label "molecular_function" ;
  rdfs:subClassOf obo:BFO_0000015 .

obo:IAO_0000180 a rdfs:Class ;
  rdfs:label "heatmap"@en ;
  rdfs:comment """A heatmap is a report graph which is a graphical representation of data
where the values taken by a variable(s) are shown as colors in a
two-dimensional map."""@en ;
  rdfs:subClassOf obo:IAO_0000038 .

obo:OBI_0000471 a rdfs:Class ;
  rdfs:label "study design execution" ;
  rdfs:comment "a planned process that carries out a study design" ;
  rdfs:subClassOf obo:OBI_0000011 .

obo:BFO_0000016 a rdfs:Class ;
  rdfs:label "disposition"@en ;
  rdfs:subClassOf obo:BFO_0000017 .

obo:OBI_0000704 a rdfs:Class ;
  rdfs:label "decision tree induction objective" ;
  rdfs:comment "A decision tree induction objective is a data transformation objective in which a tree-like graph of edges and nodes is created and from which the selection of each branch requires that some type of logical decision is made." ;
  rdfs:subClassOf obo:OBI_0200166 .

obo:IAO_0000030 a rdfs:Class ;
  rdfs:label "information content entity" ;
  rdfs:comment "An information content entity is an entity that is generically dependent on some artifact and stands in relation of aboutness to some entity." ;
  rdfs:subClassOf obo:BFO_0000031 .

obo:SDDO_3000088 a rdfs:Class ;
  rdfs:label "mission"@en ;
  rdfs:comment "Coordinated tasks and operations undertaken to meet a set of specific  objectives, within clearly delineated time and location constraints." ;
  rdfs:subClassOf obo:OBI_0000011 .

obo:SDDO_3000015 a rdf:Property ;
  rdfs:label "organizedBy"@en ;
  rdfs:range <https://w3id.org/linkml/Any> .

obo:SDDO_3000018 a rdf:Property ;
  rdfs:label "deployedOn"@en ;
  rdfs:range <https://w3id.org/linkml/Any> .

obo:SDDO_3000059 a rdfs:Class ;
  rdfs:label "space agency"@en ;
  rdfs:comment "A government agency engaged in activities related to outer space and space exploration." ;
  rdfs:subClassOf obo:SDDO_3000103 .

obo:SDDO_3000034 a rdf:Property ;
  rdfs:label "hasRole"@en ;
  rdfs:range <https://w3id.org/linkml/Any> .

obo:NCBITaxon_7742 a rdfs:Class ;
  rdfs:label "Vertebrata <vertebrates>" ;
  rdfs:subClassOf obo:NCBITaxon_33213 .

obo:OBI_0000272 a rdfs:Class ;
  rdfs:label "protocol"@en ;
  rdfs:comment "A plan specification which has sufficient level of detail and quantitative information to communicate it between investigation agents, so that different investigation agents will reliably be able to independently reproduce the process."@en ;
  rdfs:subClassOf obo:IAO_0000104 .

obo:OBI_0000458 a rdfs:Class ;
  rdfs:label "manufacturing objective"@en ;
  rdfs:comment "is the objective to manufacture a material of a certain function (device)"@en ;
  rdfs:subClassOf obo:OBI_0000456 .

obo:UBERON_0000477 a rdfs:Class ;
  rdfs:label "anatomical cluster" ;
  rdfs:comment "Anatomical group that has its parts adjacent to one another." ;
  rdfs:subClassOf obo:BFO_0000040 .

obo:SDDO_3000069 a rdfs:Class ;
  rdfs:label "study"@en ;
  rdfs:comment "A data product from the GeneLab repository" ;
  rdfs:subClassOf obo:SDDO_3000051 .

obo:OBI_0000338 a rdfs:Class ;
  rdfs:label "drawing a conclusion based on data"@en ;
  rdfs:comment "A planned process in which data gathered in an investigation is evaluated in the context of existing knowledge with the objective to generate more general conclusions or to conclude that the data does not allow one to draw general conclusion"@en ;
  rdfs:subClassOf obo:OBI_0000011 .

obo:BFO_0000001 a rdfs:Class ;
  rdfs:label "entity"@en .

obo:GO_0003824 a rdfs:Class ;
  rdfs:label "catalytic activity" ;
  rdfs:subClassOf obo:GO_0003674 .

obo:OBI_0000017 a rdfs:Class ;
  rdfs:label "regulatory role"@en ;
  rdfs:comment "a role which inheres in material entities and is realized in the processes of making, enforcing or being defined by legislation or orders issued by a governmental body."@en ;
  rdfs:subClassOf obo:BFO_0000023 .

obo:NCBITaxon_9606 a rdfs:Class ;
  rdfs:label "Homo sapiens" ;
  rdfs:subClassOf obo:NCBITaxon_314146 .

obo:IAO_0000184 a rdfs:Class ;
  rdfs:label "scatter plot"@en ;
  rdfs:comment "A scatterplot is a graph which uses Cartesian coordinates to display values for two variables for a set of data. The data is displayed as a collection of points, each having the value of one variable determining the position on the horizontal axis and the value of the other variable determining the position on the vertical axis."@en ;
  rdfs:subClassOf obo:IAO_0000038 .

obo:SDDO_3000066 a rdfs:Class ;
  rdfs:label "product"@en ;
  rdfs:comment "Any offered product or service." ;
  rdfs:subClassOf obo:IAO_0000030 .

obo:SDDO_1000008 a rdfs:Class ;
  rdfs:label "pds_Collection_with_Type_Data"@en ;
  rdfs:comment "A PDS data product from the PDS 4 data model." ;
  rdfs:subClassOf obo:SDDO_1000007 .

obo:SDDO_3000077 a rdfs:Class ;
  rdfs:label "research investigation"@en ;
  rdfs:comment "An investigation that 1) uses existing facilities and 2) is under the direction of a single individual." ;
  rdfs:subClassOf obo:SDDO_1000011 .

obo:IAO_0000007 a rdfs:Class ;
  rdfs:label "action specification"@en ;
  rdfs:comment "A directive information entity that describes an action the bearer will take."@en ;
  rdfs:subClassOf obo:IAO_0000033 .

obo:OBI_0002989 a rdfs:Class ;
  rdfs:label "material supplier" ;
  rdfs:comment "A person or organization that provides material supplies to other people or organizations." ;
  rdfs:subClassOf obo:BFO_0000040 .

obo:OBI_0001479 a rdfs:Class ;
  rdfs:label "specimen from organism"@en ;
  rdfs:comment "A specimen that derives from an anatomical part or substance arising from an organism. Examples of tissue specimen include tissue, organ, physiological system, blood, or body location (arm)." ;
  rdfs:subClassOf obo:OBI_0100051 .

obo:BFO_0000004 a rdfs:Class ;
  rdfs:label "independent continuant"@en ;
  rdfs:comment "b is an independent continuant = Def. b is a continuant which is such that there is no c and no t such that b s-depends_on c at t. (axiom label in BFO2 Reference: [017-002])"@en ;
  rdfs:subClassOf obo:BFO_0000002 .

obo:OBI_0001909 a rdfs:Class ;
  rdfs:label "conclusion based on data" ;
  rdfs:comment "An information content entity that is inferred from data." ;
  rdfs:subClassOf obo:IAO_0000030 .

obo:OBI_0000124 a rdf:Property ;
  rdfs:label "is_supported_by_data" ;
  rdfs:comment "The relation between a data item and a conclusion where the conclusion is the output of a data interpreting process and the data item is used as an input to that process" ;
  rdfs:domain obo:OBI_0001909 ;
  rdfs:range obo:IAO_0000027 .

<http://www.w3.org/ns/sosa/Observation> a rdfs:Class ;
  rdfs:label "Observation"@en ;
  rdfs:comment "Act of carrying out an (Observation) Procedure to estimate or calculate a value of a property of a FeatureOfInterest. Links to a Sensor to describe what made the Observation and how; links to an ObservableProperty to describe what the result is an estimate of, and to a FeatureOfInterest to detail what that property was associated with."@en .

obo:BFO_0000015 a rdfs:Class ;
  rdfs:label "process"@en ;
  rdfs:comment "p is a process = Def. p is an occurrent that has temporal proper parts and for some time t, p s-depends_on some material entity at t. (axiom label in BFO2 Reference: [083-003])"@en ;
  rdfs:subClassOf obo:BFO_0000003 .

obo:NCBITaxon_33154 a rdfs:Class ;
  rdfs:label "Opisthokonta" ;
  rdfs:subClassOf obo:NCBITaxon_2759 .

obo:SDDO_3000087 a rdfs:Class ;
  rdfs:label "instrument operating mode"@en ;
  rdfs:comment "An identified configuration for an instrument." ;
  rdfs:subClassOf obo:IAO_0000033 .

obo:OBI_0200188 a rdfs:Class ;
  rdfs:label "cross validation objective"@en ;
  rdfs:comment "A cross validation objective is a data transformation objective in which the aim is to partition a sample of data into subsets such that the analysis is initially performed on a single subset, while the other subset(s) are retained for subsequent use in confirming and validating the initial analysis."@en ;
  rdfs:subClassOf obo:OBI_0200172 .

obo:OBI_0200166 a rdfs:Class ;
  rdfs:label "data transformation objective"@en ;
  rdfs:comment "An objective specification to transformation input data into output data"@en ;
  rdfs:subClassOf obo:IAO_0000005 .

obo:SDDO_3000103 a rdfs:Class ;
  rdfs:label "organization"@en ;
  rdfs:comment "An entity that can bear roles, has members, and has a set of organization rules." ;
  rdfs:subClassOf <http://xmlns.com/foaf/0.1/Agent> .

obo:SDDO_3000091 a rdfs:Class ;
  rdfs:label "NASAMission"@en ;
  rdfs:comment "A  mission led or funded by NASA" ;
  rdfs:subClassOf obo:SDDO_3000088 .

obo:OBI_0001930 a rdfs:Class ;
  rdfs:label "categorical value specification" ;
  rdfs:comment "A value specification that is specifies one category out of a fixed number of nominal categories" ;
  rdfs:subClassOf obo:OBI_0001933 .

obo:SDDO_3000114 a rdfs:Class ;
  rdfs:label "NASA program" ;
  rdfs:subClassOf obo:SDDO_3000107 .

obo:SDDO_3000014 a rdf:Property ;
  rdfs:label "funds"@en ;
  rdfs:range <https://w3id.org/linkml/Any> .

obo:SDDO_1000004 a rdfs:Class ;
  rdfs:label "spase:NumericalData"@en ;
  rdfs:comment "Data stored as numerical values in one or more specified formats." ;
  rdfs:subClassOf obo:SDDO_3000051 .

obo:SDDO_3000080 a rdfs:Class ;
  rdfs:label "experiment Apparatus"@en ;
  rdfs:comment "Hardware used in conducting an experiment." ;
  rdfs:subClassOf obo:SDDO_3000054 .

obo:SDDO_3000051 a rdfs:Class ;
  rdfs:label "data product"@en ;
  rdfs:comment "A product containing science data from some investigation." ;
  rdfs:subClassOf obo:SDDO_3000066 .

obo:IAO_0000104 a rdfs:Class ;
  rdfs:label "plan specification"@en ;
  rdfs:comment "A directive information entity with action specifications and objective specifications as parts that, when concretized, is realized in a process in which the bearer tries to achieve the objectives by taking the actions specified."@en ;
  rdfs:subClassOf obo:IAO_0000033 .

obo:OBI_0000011 a rdfs:Class ;
  rdfs:label "planned process"@en ;
  rdfs:comment "A process that realizes a plan which is the concretization of a plan specification."@en ;
  rdfs:subClassOf obo:BFO_0000015 .

obo:IAO_0000033 a rdfs:Class ;
  rdfs:label "directive information entity"@en ;
  rdfs:comment "An information content entity whose concretizations indicate to their bearer how to realize them in a process."@en ;
  rdfs:subClassOf obo:IAO_0000030 .

obo:BFO_0000002 a rdfs:Class ;
  rdfs:label "continuant"@en ;
  rdfs:comment "An entity that exists in full at any time in which it exists at all, persists through time while maintaining its identity and has no temporal parts."@en ;
  rdfs:subClassOf obo:BFO_0000001 .

obo:SDDO_3000110 a rdfs:Class ;
  rdfs:label "data element" ;
  rdfs:comment "A data element is any characteristic that can help in understanding data content. That is, a data element is any parameter or variable that is useful, or critical, when identifying  or describing the content of a data object." ;
  rdfs:subClassOf obo:IAO_0000027 .

obo:SDDO_3000031 a rdf:Property ;
  rdfs:label "isResultOf"@en ;
  rdfs:range <https://w3id.org/linkml/Any> .

obo:OBI_0000953 a rdfs:Class ;
  rdfs:label "processed specimen" ;
  rdfs:comment "A specimen that has been intentionally physically modified." ;
  rdfs:subClassOf obo:OBI_0000047 , obo:OBI_0100051 .

obo:OBI_0000700 a rdfs:Class ;
  rdfs:label "support vector machine" ;
  rdfs:comment "A support vector machine is a data transformation with a class prediction objective based on the construction of a separating hyperplane that maximizes the margin between two data sets of vectors in n-dimensional space." ;
  rdfs:subClassOf obo:OBI_0000663 .

obo:SDDO_1000011 a rdfs:Class ;
  rdfs:label "investigation"@en ;
  rdfs:comment "A set of experiments and/or observations." ;
  rdfs:subClassOf obo:OBI_0000011 .

<http://www.ebi.ac.uk/swo/SWO_9000050> a rdfs:Class ;
  rdfs:label "software interface" ;
  rdfs:comment "The mode of interaction with a piece of software." ;
  rdfs:subClassOf obo:IAO_0000030 .

obo:SDDO_3000056 a rdfs:Class ;
  rdfs:label "author"@en ;
  rdfs:comment "An originator or creator of a work" ;
  rdfs:subClassOf obo:BFO_0000023 .

obo:SDDO_3000054 a rdfs:Class ;
  rdfs:label "hardware"@en ;
  rdfs:comment "The mechanical, magnetic, electronic, and electrical equipment necessary for conducting an activity." ;
  rdfs:subClassOf obo:BFO_0000040 .

<http://purl.org/vocommons/voaf#Vocabulary> a rdfs:Class .

obo:GO_0016301 a rdfs:Class ;
  rdfs:label "kinase activity" ;
  rdfs:subClassOf obo:GO_0016772 .

obo:IAO_0000064 a rdfs:Class ;
  rdfs:label "algorithm"@en ;
  rdfs:comment "A plan specification which describes the inputs and output of mathematical functions as well as workflow of execution for achieving an predefined objective. Algorithms are realized usually by means of implementation as computer programs for execution by automata."@en ;
  rdfs:subClassOf obo:IAO_0000104 .

obo:OBI_0100026 a rdfs:Class ;
  rdfs:label "organism"@en ;
  rdfs:comment "A material entity that is an individual living system, such as animal, plant, bacteria or virus, that is capable of replicating or reproducing, growth and maintenance in the right environment. An organism may be unicellular or made up, like humans, of many billions of cells divided into specialized tissues and organs."@en ;
  rdfs:subClassOf obo:BFO_0000040 .

obo:IAO_0000037 a rdfs:Class ;
  rdfs:label "dot plot"@en ;
  rdfs:comment "A dot plot is a report graph which is a graphical representation of data where each data point is represented by a single dot placed on coordinates corresponding to data point values in particular dimensions."@en ;
  rdfs:subClassOf obo:IAO_0000038 .

obo:IAO_0000101 a rdfs:Class ;
  rdfs:label "image"@en ;
  rdfs:comment "An image is an affine projection to a two dimensional surface, of measurements of some quality of an entity or entities repeated at regular intervals across a spatial range, where the measurements are represented as color and luminosity on the projected on surface."@en ;
  rdfs:subClassOf obo:IAO_0000308 .

obo:OBI_0000571 a rdfs:Class ;
  rdfs:label "manufacturer role" ;
  rdfs:comment "Manufacturer role is a role which inheres in a person or organization and which is realized by a manufacturing process." ;
  rdfs:subClassOf obo:BFO_0000023 .

obo:OBI_0000014 a rdfs:Class ;
  rdfs:label "regulator role"@en ;
  rdfs:comment "a regulatory role involved with making and/or enforcing relevant legislation and governmental orders"@en ;
  rdfs:subClassOf obo:OBI_0000017 .

obo:OBI_0200111 a rdfs:Class ;
  rdfs:label "data visualization"@en ;
  rdfs:comment "An planned process that creates images, diagrams or animations from the input data."@en ;
  rdfs:subClassOf obo:OBI_0000011 .

obo:BFO_0000019 a rdfs:Class ;
  rdfs:label "quality"@en ;
  rdfs:subClassOf obo:BFO_0000020 .

obo:SDDO_3000098 a rdfs:Class ;
  rdfs:label "facility"@en ;
  rdfs:comment "A construction, permanent or temporary, on land, in air, space or water, where scientific research or measurements can be undertaken." ;
  rdfs:subClassOf obo:BFO_0000040 .

obo:NCBITaxon_32523 a rdfs:Class ;
  rdfs:label "Tetrapoda" ;
  rdfs:subClassOf obo:NCBITaxon_117571 .

obo:SDDO_3000071 a rdfs:Class ;
  rdfs:label "factor"@en ;
  rdfs:comment "The role played by an entity as part of a scientific investigation such that levels of the measurement or observation of the entity are thought to bear upon the hypotheses being investigated." ;
  rdfs:subClassOf obo:BFO_0000023 .

obo:SDDO_3000007 a rdf:Property ;
  rdfs:label "experimentalContextFor"@en ;
  rdfs:range <https://w3id.org/linkml/Any> .

obo:RO_0000081 a rdf:Property ;
  rdfs:label "role of"@en ;
  rdfs:comment "a relation between a role and an independent continuant (the bearer), in which the role specifically depends on the bearer for its existence"@en ;
  rdfs:range <https://w3id.org/linkml/Any> ;
  rdfs:subPropertyOf obo:RO_0000052 .

<http://www.ebi.ac.uk/swo/interface/SWO_9000051> a rdfs:Class ;
  rdfs:label "web service" ;
  rdfs:comment "A web service is a software interface which works as a method of communication between two electronic devices over the World Wide Web and which is provided at a particular network address. There are two major classes of Web services: REST-compliant Web services, and arbitrary (or application-specific) Web services." ;
  rdfs:subClassOf <http://www.ebi.ac.uk/swo/SWO_9000050> .

obo:OBI_0000707 a rdfs:Class ;
  rdfs:label "decision tree building data transformation"@en ;
  rdfs:comment "A decision tree building data transformation is a data transformation that has objective decision tree induction."@en ;
  rdfs:subClassOf obo:OBI_0200000 .

obo:IAO_0000096 a rdfs:Class ;
  rdfs:label "source code module"@en ;
  rdfs:comment "A source code module is a directive information entity that specifies, using a programming language, some algorithm."@en ;
  rdfs:subClassOf obo:IAO_0000033 .

obo:OBI_0000018 a rdfs:Class ;
  rdfs:label "material supplier role"@en ;
  rdfs:comment "a role realized through the process of supplying materials such as animal subjects, reagents or other materials used in an investigation."@en ;
  rdfs:subClassOf obo:OBI_0000947 .

obo:SDDO_3000065 a rdfs:Class ;
  rdfs:label "organism"@en ;
  rdfs:comment "The quality of a living subject that indicates the taxonomical grouping of the subject.  This grouping can be at any level in a hierachy of organism classification, or a collection of levels, and can be using scientific language or colloquial language." ;
  rdfs:subClassOf obo:OBI_0100026 .

obo:SDDO_3000107 a rdfs:Class ;
  rdfs:label "program"@en ;
  rdfs:comment "A broad framework of goals to be achieved." ;
  rdfs:subClassOf obo:SDDO_3000103 .

<http://www.w3.org/ns/sosa/Sensor> a rdfs:Class ;
  rdfs:label "Sensor"@en ;
  rdfs:comment "Device, agent (including humans), or software (simulation) involved in, or implementing, a Procedure. Sensors respond to a stimulus, e.g., a change in the environment, or input data composed from the results of prior Observations, and generate a Result. Sensors can be hosted by Platforms."@en .

obo:OBI_0000066 a rdfs:Class ;
  rdfs:label "investigation"@en ;
  rdfs:comment "a planned process that consists of parts: planning, study design execution, documentation and which produce conclusion(s)."@en ;
  rdfs:subClassOf obo:OBI_0000011 .

obo:BFO_0000020 a rdfs:Class ;
  rdfs:label "specifically dependent continuant"@en ;
  rdfs:comment "A continuant that inheres in or is borne by other entities. Every instance of A requires some specific instance of B which must always be the same."@en ;
  rdfs:subClassOf obo:BFO_0000002 .

obo:APOLLO_SV_00000796 a rdfs:Class ;
  rdfs:label "dataset creating"@en ;
  rdfs:comment "A planned process that has a data set as its specified output."@en ;
  rdfs:subClassOf obo:OBI_0000011 .

obo:SDDO_1000007 a rdfs:Class ;
  rdfs:label "PDS data product"@en ;
  rdfs:comment "A product from the PDS data system" ;
  rdfs:subClassOf obo:SDDO_3000051 .

<http://xmlns.com/foaf/0.1/Agent> a rdfs:Class ;
  rdfs:subClassOf obo:BFO_0000004 .

obo:SDDO_3000060 a rdfs:Class ;
  rdfs:label "instrument host"@en ;
  rdfs:comment "The physical object upon or within which an instrument is mounted." ;
  rdfs:subClassOf obo:BFO_0000023 , <http://www.w3.org/ns/sosa/Platform> .

obo:NCBITaxon_2759 a rdfs:Class ;
  rdfs:label "Eukaryota" ;
  rdfs:subClassOf obo:OBI_0100026 .

obo:SDDO_3000086 a rdfs:Class ;
  rdfs:label "funder"@en ;
  rdfs:comment "A role in which the bearer delivers financial support to enable some activity." ;
  rdfs:subClassOf obo:BFO_0000023 .

obo:OBI_0000245 a rdfs:Class ;
  rdfs:label "organization"@en ;
  rdfs:comment "An entity that can bear roles, has members, and has a set of organization rules. Members of organizations are either organizations themselves or individual people. Members can bear specific organization member roles that are determined in the organization rules. The organization rules also determine how decisions are made on behalf of the organization by the organization members."@en ;
  rdfs:subClassOf obo:BFO_0000040 .

obo:IAO_0000003 a rdfs:Class ;
  rdfs:label "measurement unit label"@en ;
  rdfs:comment "A measurement unit label is as a label that is part of a scalar measurement datum and denotes a unit of measure."@en ;
  rdfs:subClassOf obo:IAO_0000009 .

obo:SDDO_3000113 a rdfs:Class ;
  rdfs:label "firmware"@en ;
  rdfs:comment "Software that provides the low-level control for a device's specific hardware." ;
  rdfs:subClassOf obo:IAO_0000010 .

<http://www.ebi.ac.uk/swo/interface/SWO_9000052> a rdfs:Class ;
  rdfs:label "graphical user interface" ;
  rdfs:comment "https://en.wikipedia.org/wiki/Graphical_user_interface, accessed 6 June 2013." ;
  rdfs:subClassOf <http://www.ebi.ac.uk/swo/SWO_9000050> .

obo:OBI_0200050 a rdfs:Class ;
  rdfs:label "dimensionality reduction"@en ;
  rdfs:comment "A dimensionality reduction is data partitioning which transforms each input m-dimensional vector (x_1, x_2, ..., x_m) into an output n-dimensional vector (y_1, y_2, ..., y_n), where n is smaller than m."@en ;
  rdfs:subClassOf obo:APOLLO_SV_00000796 , obo:OBI_0200175 .

obo:SDDO_3000090 a rdfs:Class ;
  rdfs:label "person"@en ;
  rdfs:comment "An agent that is a human being." ;
  rdfs:subClassOf <http://xmlns.com/foaf/0.1/Agent> .

obo:SDDO_1000003 a rdfs:Class ;
  rdfs:label "spase:Catalog"@en ;
  rdfs:comment "A tabular listing of events or observational notes, especially those that have utility in aiding a user in locating data." ;
  rdfs:subClassOf obo:SDDO_3000051 .

obo:OBI_0000339 a rdfs:Class ;
  rdfs:label "planning"@en ;
  rdfs:comment "a process of creating or modifying a plan specification"@en .

obo:OBI_0200190 a rdfs:Class ;
  rdfs:label "clustered data visualization" ;
  rdfs:comment "A data visualization which has input of a clustered data set and produces an output of a report graph which is capable of rendering data of this type." ;
  rdfs:subClassOf obo:OBI_0200111 .

obo:SDDO_3000081 a rdfs:Class ;
  rdfs:label "deployment"@en ;
  rdfs:comment "The realisation of an application, or execution of a plan, idea, model, design, specification, standard, algorithm, or policy." ;
  rdfs:subClassOf obo:OBI_0000011 .

obo:IAO_0000038 a rdfs:Class ;
  rdfs:label "graph"@en ;
  rdfs:comment "A diagram that presents one or more tuples of information by mapping those tuples in to a two dimensional space in a non arbitrary way."@en ;
  rdfs:subClassOf obo:IAO_0000309 .

obo:SDDO_3000092 a rdfs:Class ;
  rdfs:label "instrument"@en ;
  rdfs:comment "An instrument is a physical object that can be used to collect data." ;
  rdfs:subClassOf obo:SDDO_3000075 , <http://www.w3.org/ns/sosa/Sensor> .

obo:SDDO_3000029 a rdf:Property ;
  rdfs:label "present"@en ;
  rdfs:range <https://w3id.org/linkml/Any> .

obo:SDDO_3000039 a rdf:Property ;
  rdfs:label "operatesOn"@en ;
  rdfs:range <https://w3id.org/linkml/Any> .

obo:OBI_0200041 a rdfs:Class ;
  rdfs:label "k-means clustering"@en ;
  rdfs:comment "A k-means clustering is a data transformation which achieves a class discovery or partitioning objective, which takes as input a collection of objects (represented as points in multidimensional space) and which partitions them into a specified number k of clusters. The algorithm attempts to find the centers of natural clusters in the data. The most common form of the algorithm starts by partitioning the input points into k initial sets, either at random or using some heuristic data. It then calculates the mean point, or centroid, of each set. It constructs a new partition by associating each point with the closest centroid. Then the centroids are recalculated for the new clusters, and the algorithm repeated by alternate applications of these two steps until convergence, which is obtained when the points no longer switch clusters (or alternatively centroids are no longer changed)."@en ;
  rdfs:subClassOf obo:APOLLO_SV_00000796 , obo:OBI_0200171 , obo:OBI_0200175 .

obo:IAO_0000102 a rdfs:Class ;
  rdfs:label "data about an ontology part"@en ;
  rdfs:comment "Data about an ontology part is a data item about a part of an ontology, for example a term"@en ;
  rdfs:subClassOf obo:IAO_0000027 .

obo:OBI_0000648 a rdfs:Class ;
  rdfs:label "clustered data set"@en ;
  rdfs:comment "A data set that is produced as the output of a class discovery data transformation and consists of a data set with assigned discovered class labels."@en ;
  rdfs:subClassOf obo:IAO_0000100 .

obo:PATO_0000001 a rdfs:Class ;
  rdfs:label "quality" ;
  rdfs:subClassOf obo:BFO_0000020 .

obo:IAO_0000010 a rdfs:Class ;
  rdfs:label "software"@en ;
  rdfs:comment """Software is a plan specification composed of a series of instructions that can be 
interpreted by or directly executed by a processing unit."""@en ;
  rdfs:subClassOf obo:IAO_0000104 .

obo:SDDO_3000078 a rdfs:Class ;
  rdfs:label "specimen"@en ;
  rdfs:comment "A part of a feature, taken to demonstrate or to determine the character of the whole." ;
  rdfs:subClassOf obo:OBI_0100051 .

obo:SDDO_3000021 a rdf:Property ;
  rdfs:label "usedIn"@en ;
  rdfs:range <https://w3id.org/linkml/Any> .

obo:OBI_0002215 a rdfs:Class ;
  rdfs:label "histologic grade for ovarian tumor" ;
  rdfs:comment "A categorical value specification that is a histologic grade assigned to a ovarian tumor." ;
  rdfs:subClassOf obo:OBI_0001930 .

obo:OBI_0000202 a rdfs:Class ;
  rdfs:label "investigation agent role" ;
  rdfs:comment "A role borne by an entity and that is realized in a process that is part of an investigation in which an objective is achieved. These processes include, among others: planning, overseeing, funding, reviewing."@en ;
  rdfs:subClassOf obo:BFO_0000023 .

obo:SDDO_1000001 a rdfs:Class ;
  rdfs:label "pds_Data_Set_PDS3"@en ;
  rdfs:comment "A PDS data product from the PDS 3 data model." ;
  rdfs:subClassOf obo:SDDO_1000007 .

obo:APOLLO_SV_00000008 a rdfs:Class ;
  rdfs:label "software development"@en ;
  rdfs:comment "A planned process that has specified output a software product and that involves the creation of source code."@en ;
  rdfs:subClassOf obo:OBI_0000011 .

obo:SDDO_1000012 a rdfs:Class ;
  rdfs:label "observing campaign"@en ;
  rdfs:comment "A campaign that 1) uses primarily but not exclusively existing facilities and 2) after and possibly during which other investigations are carried out using the same facilities." ;
  rdfs:subClassOf obo:SDDO_3000045 .

obo:OBI_0000112 a rdfs:Class ;
  rdfs:label "specimen role"@en ;
  rdfs:comment "a role borne by a material entity that is gained during a specimen collection process and that can be realized by use of the specimen in an investigation"@en ;
  rdfs:subClassOf obo:BFO_0000023 .

obo:OBI_0200175 a rdfs:Class ;
  rdfs:label "class discovery data transformation"@en ;
  rdfs:comment "A class discovery data transformation (sometimes called unsupervised classification) is a data transformation that has objective class discovery."@en ;
  rdfs:subClassOf obo:OBI_0200000 .

obo:BFO_0000003 a rdfs:Class ;
  rdfs:label "occurrent"@en ;
  rdfs:comment "An entity that has temporal parts and that happens, unfolds or develops through time."@en ;
  rdfs:subClassOf obo:BFO_0000001 .

obo:NCBITaxon_33213 a rdfs:Class ;
  rdfs:label "Bilateria" ;
  rdfs:subClassOf obo:NCBITaxon_33208 .

obo:OBI_0200178 a rdfs:Class ;
  rdfs:label "class discovery objective"@en ;
  rdfs:comment "A class discovery objective (sometimes called unsupervised classification) is a data transformation objective where the aim is to organize input data  (typically vectors of attributes) into classes, where the number of classes and their specifications are not known a priori. Depending on usage, the class assignment can be definite or probabilistic."@en ;
  rdfs:subClassOf obo:OBI_0200166 .

obo:OBI_0100051 a rdfs:Class ;
  rdfs:label "specimen"@en ;
  rdfs:comment "A material entity that has the specimen role."@en ;
  rdfs:subClassOf obo:BFO_0000040 .

obo:OBI_0000456 a rdfs:Class ;
  rdfs:label "material transformation objective"@en ;
  rdfs:comment "an objective specifiction that creates an specific output object from input materials."@en ;
  rdfs:subClassOf obo:IAO_0000005 .

obo:OBI_0200179 a rdfs:Class ;
  rdfs:label "class prediction objective"@en ;
  rdfs:comment """A class prediction objective (sometimes called supervised classification) is a data transformation objective where the aim is to create a predictor from training data through a machine learning technique. The training data consist of pairs of objects (typically vectors of attributes) and
class labels for these objects. The resulting predictor can be used to attach class labels to any valid novel input object. Depending on usage, the prediction can be definite or probabilistic. A classification is learned from the training data and can then be tested on test data."""@en ;
  rdfs:subClassOf obo:OBI_0200166 .

obo:SDDO_3000101 a rdfs:Class ;
  rdfs:label "photoGallery"@en ;
  rdfs:comment "A graphical user interface that provides access to photographs/images." ;
  rdfs:subClassOf <http://www.ebi.ac.uk/swo/interface/SWO_9000052> .

obo:SDDO_3000089 a rdfs:Class ;
  rdfs:label "laboratoryProcedure"@en ;
  rdfs:comment "Any procedure that involves testing or manipulating a sample or subject in a laboratory setting" ;
  rdfs:subClassOf obo:OBI_0000011 .

obo:BFO_0000031 a rdfs:Class ;
  rdfs:label "generically dependent continuant"@en ;
  rdfs:comment "A continuant that is dependent on one or other independent continuant bearers. For every instance of A requires some instance of (an independent continuant type) B but which instance of B serves can change from time to time."@en ;
  rdfs:subClassOf obo:BFO_0000002 .

obo:OBI_0200000 a rdfs:Class ;
  rdfs:label "data transformation"@en ;
  rdfs:comment "A planned process that produces output data from input data."@en ;
  rdfs:subClassOf obo:OBI_0000011 .

obo:OBI_0000727 a rdfs:Class ;
  rdfs:label "k-nearest neighbors"@en ;
  rdfs:comment "A k-nearest neighbors is a data transformation which achieves a class discovery or partitioning objective, in which an input data object with vector y is assigned to a class label based upon the k closest training data set points to y; where k is the largest value that class label is assigned."@en ;
  rdfs:subClassOf obo:APOLLO_SV_00000796 , obo:OBI_0200171 , obo:OBI_0200175 .

obo:OBI_0000659 a rdfs:Class ;
  rdfs:label "specimen collection process" ;
  rdfs:comment "A planned process with the objective of collecting a specimen." ;
  rdfs:subClassOf obo:OBI_0000011 .

obo:SDDO_3000075 a rdfs:Class ;
  rdfs:label "access interface"@en ;
  rdfs:comment "A software interface that 1) presents users with selection criteria and 2) presents products or services that meet the criteria the user then selects." ;
  rdfs:subClassOf <http://www.ebi.ac.uk/swo/SWO_9000050> .

<https://w3id.org/linkml/Any> a rdfs:Class ;
  rdfs:comment "An unconstrained type or object" .

obo:SDDO_3000096 a rdfs:Class ;
  rdfs:label "feature"@en ;
  rdfs:comment "A material entity that has characteristics that can be qualified or quantified through observation or experiment." ;
  rdfs:subClassOf obo:BFO_0000040 , obo:SDDO_3000099 .

obo:IAO_0000005 a rdfs:Class ;
  rdfs:label "objective specification"@en ;
  rdfs:comment "A directive information entity that describes an intended process endpoint. When part of a plan specification the concretization is realized in a planned process in which the bearer tries to effect the world so that the process endpoint is achieved."@en ;
  rdfs:subClassOf obo:IAO_0000033 .

obo:IAO_0000179 a rdfs:Class ;
  rdfs:label "histogram"@en ;
  rdfs:comment """A histogram is a report graph which is a statistical description of a
distribution in terms of occurrence frequencies of different event classes."""@en ;
  rdfs:subClassOf obo:IAO_0000038 .

obo:NCBITaxon_40674 a rdfs:Class ;
  rdfs:label "Mammalia" ;
  rdfs:subClassOf obo:NCBITaxon_32524 .

obo:NCBITaxon_10239 a rdfs:Class ;
  rdfs:label "Viruses" ;
  rdfs:subClassOf obo:OBI_0100026 .

obo:IAO_0000027 a rdfs:Class ;
  rdfs:label "data item"@en ;
  rdfs:comment "An information content entity that is intended to be a truthful statement about something (modulo, e.g., measurement precision or other systematic errors) and is constructed/acquired by a method which reliably tends to produce (approximately) truthful statements."@en ;
  rdfs:subClassOf obo:IAO_0000030 .

obo:NCBITaxon_32524 a rdfs:Class ;
  rdfs:label "Amniota" ;
  rdfs:subClassOf obo:NCBITaxon_32523 .

obo:SDDO_3000045 a rdfs:Class ;
  rdfs:label "campaign"@en ;
  rdfs:comment "A systematic set of activities undertaken to meet a particular science objective." ;
  rdfs:subClassOf obo:SDDO_1000011 .

obo:IAO_0000310 a rdfs:Class ;
  rdfs:label "document"@en ;
  rdfs:comment "A collection of information content entities intended to be understood together as a whole"@en ;
  rdfs:subClassOf obo:IAO_0000030 .

obo:NCBITaxon_2 a rdfs:Class ;
  rdfs:label "Bacteria" ;
  rdfs:subClassOf obo:OBI_0100026 .

obo:OBI_0002076 a rdfs:Class ;
  rdfs:label "collection of specimens"@en ;
  rdfs:comment "A material entity that has two or more specimens as its parts."@en ;
  rdfs:subClassOf obo:BFO_0000040 .

obo:RO_0002351 a rdf:Property ;
  rdfs:label "has member"@en ;
  rdfs:comment "has member is a mereological relation between a collection and an item." ;
  rdfs:range obo:OBI_0100051 ;
  rdfs:subPropertyOf obo:BFO_0000051 .

obo:BFO_0000179 a rdf:Property ;
  rdfs:label "BFO OWL specification label"@en ;
  rdfs:comment "Relates an entity in the ontology to the name of the variable that is used to represent it in the code that generates the BFO OWL file from the lispy specification."@en ;
  rdfs:range xsd:string .

obo:IAO_0000111 a rdf:Property ;
  rdfs:label "editor preferred label" ;
  rdfs:comment "The concise, meaningful, and human-friendly name for a class or property preferred by the ontology developers. (US-English)"@en ;
  rdfs:range xsd:string .

obo:IAO_0000112 a rdf:Property ;
  rdfs:label "example of usage" ;
  rdfs:comment "A phrase describing how a class name should be used. May also include other kinds of examples that facilitate immediate understanding of a class semantics, such as widely known prototypical subclasses or instances of the class. Although essential for high level terms, examples for low level terms (e.g., Affymetrix HU133 array) are not." ;
  rdfs:range xsd:string .

obo:IAO_0000115 a rdf:Property ;
  rdfs:label "textual definition" ;
  rdfs:comment "The official OBI definition, explaining the meaning of a class or property. Shall be Aristotelian, formalized and normalized. Can be augmented with colloquial definitions."@en ;
  rdfs:range xsd:string .

obo:IAO_0000116 a rdf:Property ;
  rdfs:label "editor note"@en ;
  rdfs:comment "An administrative note intended for its editor. It may not be included in the publication version of the ontology, so it should contain nothing necessary for end users to understand the ontology."@en ;
  rdfs:range xsd:string .

obo:IAO_0000117 a rdf:Property ;
  rdfs:label "term editor"@en ;
  rdfs:comment "Name of editor entering the term in the file. The term editor is a point of contact for information regarding the term. The term editor may be, but is not always, the author of the definition, which may have been worked upon by several people"@en ;
  rdfs:range xsd:string .

obo:IAO_0000118 a rdf:Property ;
  rdfs:label "alternative term" ;
  rdfs:comment "A label for a class or property that can be used to refer to the class or property instead of the preferred rdfs:label. Alternative labels should be used to indicate community- or context-specific labels, abbreviations, shorthand forms and the like."@en ;
  rdfs:range xsd:string .

obo:IAO_0000119 a rdf:Property ;
  rdfs:label "definition source" ;
  rdfs:comment "Formal citation, e.g. identifier in external database to indicate / attribute source(s) for the definition. Free text indicate / attribute source(s) for the definition. EXAMPLE: Author Name, URI, MeSH Term C04, PUBMED ID, Wiki uri on 31.01.2007"@en ;
  rdfs:range xsd:string .

obo:OBI_0000295 a rdf:Property ;
  rdfs:label "is_specified_input_of"@en ;
  rdfs:comment "A relation between a planned process and a continuant participating in that process that is not created during  the process. The presence of the continuant during the process is explicitly specified in the plan specification which the process realizes the concretization of."@en ;
  rdfs:range obo:OBI_0000011 ;
  rdfs:subPropertyOf obo:RO_0000056 .

obo:RO_0000052 a rdf:Property ;
  rdfs:label "inheres in"@en ;
  rdfs:comment "a relation between a specifically dependent continuant (the characteristic) and any other entity (the bearer), in which the characteristic depends on the bearer for its existence."@en ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002314 .

obo:RO_0000053 a rdf:Property ;
  rdfs:label "has characteristic"@en ;
  rdfs:comment "a relation between an independent continuant (the bearer) and a specifically dependent continuant (the dependent), in which the dependent specifically depends on the bearer for its existence"@en ;
  rdfs:range obo:BFO_0000020 .

obo:RO_0000080 a rdf:Property ;
  rdfs:label "quality of"@en ;
  rdfs:comment "a relation between a quality and an independent continuant (the bearer), in which the quality specifically depends on the bearer for its existence"@en ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0000052 .

obo:RO_0000086 a rdf:Property ;
  rdfs:label "has quality"@en ;
  rdfs:comment "a relation between an independent continuant (the bearer) and a quality, in which the quality specifically depends on the bearer for its existence"@en ;
  rdfs:range obo:BFO_0000019 ;
  rdfs:subPropertyOf obo:RO_0000053 .

obo:RO_0000092 a rdf:Property ;
  rdfs:label "disposition of"@en ;
  rdfs:comment "inverse of has disposition" ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0000052 .

obo:RO_0001001 a rdf:Property ;
  rdfs:label "derives into"@en ;
  rdfs:comment "a relation between two distinct material entities, the old entity and the new entity, in which the new entity begins to exist when the old entity ceases to exist, and the new entity inherits the significant portion of the matter of the old entity"@en ;
  rdfs:range <https://w3id.org/linkml/Any> .

obo:RO_0002013 a rdf:Property ;
  rdfs:label "has regulatory component activity" ;
  rdfs:comment "A 'has regulatory component activity' B if A and B are GO molecular functions (GO_0003674), A has_component B and A is regulated by B." ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002334 , obo:RO_0002017 .

obo:RO_0002014 a rdf:Property ;
  rdfs:label "has negative regulatory component activity" ;
  rdfs:comment "A relationship that holds between a GO molecular function and a component of that molecular function that negatively regulates the activity of the whole.  More formally, A 'has regulatory component activity' B iff :A and B are GO molecular functions (GO_0003674), A has_component B and A is negatively regulated by B." ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002335 , obo:RO_0002013 .

obo:RO_0002015 a rdf:Property ;
  rdfs:label "has positive regulatory component activity" ;
  rdfs:comment "A relationship that holds between a GO molecular function and a component of that molecular function that positively regulates the activity of the whole.  More formally, A 'has regulatory component activity' B iff :A and B are GO molecular functions (GO_0003674), A has_component B and A is positively regulated by B." ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002336 , obo:RO_0002013 .

obo:RO_0002017 a rdf:Property ;
  rdfs:label "has component activity" ;
  rdfs:comment "A 'has component activity' B if A is A and B are molecular functions (GO_0003674) and A has_component B." ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002018 .

obo:RO_0002022 a rdf:Property ;
  rdfs:label "directly regulated by" ;
  rdfs:comment "Process(P2) is directly regulated by process(P1) iff: P1 regulates P2 via direct physical interaction between an agent executing P1 (or some part of P1) and an agent executing P2 (or some part of P2).  For example, if protein A has protein binding activity(P1) that targets protein B and this binding  regulates the kinase activity (P2) of protein B then P1 directly regulates P2." ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002334 .

obo:RO_0002023 a rdf:Property ;
  rdfs:label "directly negatively regulated by" ;
  rdfs:comment "Process(P2) is directly negatively regulated by process(P1) iff: P1 negatively regulates P2 via direct physical interaction between an agent executing P1 (or some part of P1) and an agent executing P2 (or some part of P2).  For example, if protein A has protein binding activity(P1) that targets protein B and this binding  negatively regulates the kinase activity (P2) of protein B then P2 directly negatively regulated by P1." ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002022 .

obo:RO_0002024 a rdf:Property ;
  rdfs:label "directly positively regulated by" ;
  rdfs:comment "Process(P2) is directly postively regulated by process(P1) iff: P1 positively regulates P2 via direct physical interaction between an agent executing P1 (or some part of P1) and an agent executing P2 (or some part of P2).  For example, if protein A has protein binding activity(P1) that targets protein B and this binding positively regulates the kinase activity (P2) of protein B then P2 is directly postively regulated by P1." ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002022 .

obo:RO_0002025 a rdf:Property ;
  rdfs:label "has effector activity" ;
  rdfs:comment "A 'has effector activity' B if A and B are GO molecular functions (GO_0003674),  A 'has component activity' B and B is the effector (output function) of B.  Each compound function has only one effector activity." ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002017 .

obo:RO_0002086 a rdf:Property ;
  rdfs:label "ends after"@en ;
  rdfs:comment "X ends_after Y iff: end(Y) before_or_simultaneous_with end(X)"@en ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002222 .

obo:RO_0002087 a rdf:Property ;
  rdfs:label "immediately preceded by"@en ;
  rdfs:comment "X immediately_preceded_by Y iff: end(X) simultaneous_with start(Y)"@en ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:BFO_0000062 .

obo:RO_0002090 a rdf:Property ;
  rdfs:label "immediately precedes"@en ;
  rdfs:comment "X immediately_precedes_Y iff: end(X) simultaneous_with start(Y)"@en ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:BFO_0000063 .

obo:RO_0002131 a rdf:Property ;
  rdfs:label "overlaps"@en ;
  rdfs:comment "x overlaps y if and only if there exists some z such that x has part z and z part of y" ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002323 .

obo:RO_0002180 a rdf:Property ;
  rdfs:label "has component"@en ;
  rdfs:comment "w 'has component' p if w 'has part' p and w is such that it can be directly disassembled into into n parts p, p2, p3, ..., pn, where these parts are of similar type." ;
  rdfs:seeAlso <http://ontologydesignpatterns.org/wiki/Submissions:Componency> ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:BFO_0000051 .

obo:RO_0002212 a rdf:Property ;
  rdfs:label "negatively regulates"@en ;
  rdfs:comment "p negatively regulates q iff p regulates q, and p decreases the rate or magnitude of execution of q." ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002305 , obo:RO_0002211 .

obo:RO_0002213 a rdf:Property ;
  rdfs:label "positively regulates"@en ;
  rdfs:comment "p positively regulates q iff p regulates q, and p increases the rate or magnitude of execution of q." ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002304 , obo:RO_0002211 .

obo:RO_0002216 a rdf:Property ;
  rdfs:label "capable of part of"@en ;
  rdfs:comment "c stands in this relationship to p if and only if there exists some p' such that c is capable_of p', and p' is part_of p." ;
  rdfs:seeAlso <http://purl.obolibrary.org/obo/ro/docs/reflexivity/> ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002500 , obo:RO_0002328 .

obo:RO_0002259 a rdf:Property ;
  rdfs:range xsd:string .

obo:RO_0002263 a rdf:Property ;
  rdfs:label "acts upstream of" ;
  rdfs:comment "c acts upstream of p if and only if c enables some f that is involved in p' and p' occurs chronologically before p, is not part of p, and affects the execution of p. c is a material entity and f, p, p' are processes." ;
  rdfs:seeAlso <http://wiki.geneontology.org/index.php/Acts_upstream_of> ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002264 .

obo:RO_0002264 a rdf:Property ;
  rdfs:label "acts upstream of or within" ;
  rdfs:comment "c acts upstream of or within p if c is enables f, and f is causally upstream of or within p. c is a material entity and p is an process." ;
  rdfs:seeAlso <http://wiki.geneontology.org/index.php/Acts_upstream_of_or_within> ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002500 .

obo:RO_0002304 a rdf:Property ;
  rdfs:label "causally upstream of, positive effect" ;
  rdfs:comment "p is causally upstream of, positive effect q iff p is casually upstream of q, and the execution of p is required for the execution of q." ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0004047 , obo:RO_0002411 .

obo:RO_0002305 a rdf:Property ;
  rdfs:label "causally upstream of, negative effect" ;
  rdfs:comment "p is causally upstream of, negative effect q iff p is casually upstream of q, and the execution of p decreases the execution of q." ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0004046 , obo:RO_0002411 .

obo:RO_0002314 a rdf:Property ;
  rdfs:label "characteristic of part of"@en ;
  rdfs:comment "q characteristic of part of w if and only if there exists some p such that q inheres in p and p part of w." ;
  rdfs:seeAlso <http://purl.obolibrary.org/obo/ro/docs/reflexivity/> ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002502 .

obo:RO_0002323 a rdf:Property ;
  rdfs:label "mereotopologically related to"@en ;
  rdfs:comment "A mereological relationship or a topological relationship" ;
  rdfs:range <https://w3id.org/linkml/Any> .

obo:RO_0002327 a rdf:Property ;
  rdfs:label "enables"@en ;
  rdfs:comment "c enables p iff c is capable of p and c acts to execute p." ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002215 .

obo:RO_0002328 a rdf:Property ;
  rdfs:label "functionally related to"@en ;
  rdfs:comment "A grouping relationship for any relationship directly involving a function, or that holds because of a function of one of the related entities." ;
  rdfs:range <https://w3id.org/linkml/Any> .

obo:RO_0002329 a rdf:Property ;
  rdfs:label "part of structure that is capable of"@en ;
  rdfs:comment "this relation holds between c and p when c is part of some c', and c' is capable of p." ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002328 .

obo:RO_0002331 a rdf:Property ;
  rdfs:label "involved in"@en ;
  rdfs:comment "c involved_in p if and only if c enables some process p', and p' is part of p" ;
  rdfs:seeAlso <http://wiki.geneontology.org/index.php/Involved_in> ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002431 , obo:RO_0000056 .

obo:RO_0002333 a rdf:Property ;
  rdfs:label "enabled by"@en ;
  rdfs:comment "inverse of enables" ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002328 , obo:RO_0000057 .

obo:RO_0002335 a rdf:Property ;
  rdfs:label "negatively regulated by"@en ;
  rdfs:comment "inverse of negatively regulates" ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002334 .

obo:RO_0002336 a rdf:Property ;
  rdfs:label "positively regulated by"@en ;
  rdfs:comment "inverse of positively regulates" ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002334 .

obo:RO_0002350 a rdf:Property ;
  rdfs:label "member of"@en ;
  rdfs:comment "is member of is a mereological relation between a item and a collection." ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:BFO_0000050 .

obo:RO_0002352 a rdf:Property ;
  rdfs:label "input of"@en ;
  rdfs:comment "inverse of has input" ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002328 , obo:RO_0000056 .

obo:RO_0002404 a rdf:Property ;
  rdfs:label "causally downstream of"@en ;
  rdfs:comment "inverse of upstream of" ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002427 , obo:BFO_0000062 .

obo:RO_0002405 a rdf:Property ;
  rdfs:label "immediately causally downstream of"@en ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002404 , obo:RO_0002087 .

obo:RO_0002407 a rdf:Property ;
  rdfs:label "indirectly positively regulates"@en ;
  rdfs:comment "p indirectly positively regulates q iff p is indirectly causally upstream of q and p positively regulates q." ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0012012 , obo:RO_0002213 .

obo:RO_0002409 a rdf:Property ;
  rdfs:label "indirectly negatively regulates"@en ;
  rdfs:comment "p indirectly negatively regulates q iff p is indirectly causally upstream of q and p negatively regulates q." ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0012012 , obo:RO_0002212 .

obo:RO_0002410 a rdf:Property ;
  rdfs:label "causally related to"@en ;
  rdfs:comment "relation that links two events, processes, states, or objects such that one event, process, state, or object (a cause) contributes to the production of another event, process, state, or object (an effect) where the cause is partly or wholly responsible for the effect, and the effect is partly or wholly dependent on the cause." ;
  rdfs:range <https://w3id.org/linkml/Any> .

obo:RO_0002411 a rdf:Property ;
  rdfs:label "causally upstream of"@en ;
  rdfs:comment "p is causally upstream of q iff p is causally related to q, the end of p precedes the end of q, and p is not an occurrent part of q." ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002418 , obo:BFO_0000063 .

obo:RO_0002412 a rdf:Property ;
  rdfs:label "immediately causally upstream of"@en ;
  rdfs:comment "p is immediately causally upstream of q iff p is causally upstream of q, and the end of p is coincident with the beginning of q." ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002411 , obo:RO_0002090 .

obo:RO_0002418 a rdf:Property ;
  rdfs:label "causally upstream of or within" ;
  rdfs:comment "p is 'causally upstream or within' q iff p is causally related to q, and the end of p precedes, or is coincident with, the end of q." ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002501 .

obo:RO_0002427 a rdf:Property ;
  rdfs:label "causally downstream of or within" ;
  rdfs:comment "inverse of causally upstream of or within" ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002501 .

obo:RO_0002428 a rdf:Property ;
  rdfs:label "involved in regulation of" ;
  rdfs:comment "c involved in regulation of p if c is involved in some p' and p' regulates some p" ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002431 , obo:RO_0002263 .

obo:RO_0002429 a rdf:Property ;
  rdfs:label "involved in positive regulation of" ;
  rdfs:comment "c involved in regulation of p if c is involved in some p' and p' positively regulates some p" ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002428 .

obo:RO_0002430 a rdf:Property ;
  rdfs:label "involved in negative regulation of" ;
  rdfs:comment "c involved in regulation of p if c is involved in some p' and p' negatively regulates some p" ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002428 .

obo:RO_0002431 a rdf:Property ;
  rdfs:label "involved in or involved in regulation of" ;
  rdfs:comment "c involved in or regulates p if and only if either (i) c is involved in p or (ii) c is involved in regulation of p" ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002328 , obo:RO_0002500 , obo:RO_0002264 .

obo:RO_0002436 a rdf:Property ;
  rdfs:label "molecularly interacts with" ;
  rdfs:comment "An interaction relationship in which the two partners are molecular entities that directly physically interact with each other for example via a stable binding interaction or a brief interaction during which one modifies the other." ;
  rdfs:seeAlso obo:ECO_0000353 ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002434 .

obo:RO_0002447 a rdf:Property ;
  rdfs:label "phosphorylates" ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002436 .

obo:RO_0002464 a rdf:Property ;
  rdfs:label "helper property (not for use in curation)" ;
  rdfs:range <https://w3id.org/linkml/Any> .

obo:RO_0002481 a rdf:Property ;
  rdfs:label "is kinase activity" ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002564 .

obo:RO_0002500 a rdf:Property ;
  rdfs:label "causal agent in process" ;
  rdfs:comment "A relationship between a material entity and a process where the material entity has some causal role that influences the process" ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002595 .

obo:RO_0002502 a rdf:Property ;
  rdfs:label "depends on" ;
  rdfs:seeAlso obo:BFO_0000169 ;
  rdfs:range <https://w3id.org/linkml/Any> .

obo:RO_0002559 a rdf:Property ;
  rdfs:label "causally influenced by" ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002506 .

obo:RO_0002563 a rdf:Property ;
  rdfs:label "interaction relation helper property" ;
  rdfs:seeAlso <http://ontologydesignpatterns.org/wiki/Submissions:N-Ary_Relation_Pattern_%28OWL_2%29> , <http://purl.obolibrary.org/obo/ro/docs/interaction-relations/> ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002464 .

obo:RO_0002564 a rdf:Property ;
  rdfs:label "molecular interaction relation helper property" ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002563 .

obo:RO_0002578 a rdf:Property ;
  rdfs:label "directly regulates" ;
  rdfs:comment "p directly regulates q iff p is immediately causally upstream of q and p regulates q." ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002412 , obo:RO_0002211 .

obo:RO_0002581 a rdf:Property ;
  rdfs:label "is a defining property chain axiom" ;
  rdfs:comment "If R <- P o Q is a defining property chain axiom, then it also holds that R -> P o Q. Note that this cannot be expressed directly in OWL" ;
  rdfs:range xsd:string .

obo:RO_0002582 a rdf:Property ;
  rdfs:label "is a defining property chain axiom where second argument is reflexive" ;
  rdfs:comment "If R <- P o Q is a defining property chain axiom, then (1) R -> P o Q holds and (2) Q is either reflexive or locally reflexive. A corollary of this is that P SubPropertyOf R." ;
  rdfs:range xsd:string .

obo:RO_0002584 a rdf:Property ;
  rdfs:label "has part structure that is capable of" ;
  rdfs:comment "s 'has part structure that is capable of' p if and only if there exists some part x such that s 'has part' x and x 'capable of' p" ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002595 , obo:RO_0002328 .

obo:RO_0002596 a rdf:Property ;
  rdfs:label "capable of regulating" ;
  rdfs:comment "Holds between c and p if and only if c is capable of some activity a, and a regulates p." ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002500 .

obo:RO_0002597 a rdf:Property ;
  rdfs:label "capable of negatively regulating" ;
  rdfs:comment "Holds between c and p if and only if c is capable of some activity a, and a negatively regulates p." ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002596 .

obo:RO_0002598 a rdf:Property ;
  rdfs:label "capable of positively regulating" ;
  rdfs:comment "Holds between c and p if and only if c is capable of some activity a, and a positively regulates p." ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002596 .

obo:RO_0002608 a rdf:Property ;
  rdfs:label "process has causal agent" ;
  rdfs:comment "Inverse of 'causal agent in process'" ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002410 .

obo:RO_0002629 a rdf:Property ;
  rdfs:label "directly positively regulates" ;
  rdfs:comment "p directly positively regulates q iff p is immediately causally upstream of q, and p positively regulates q." ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002578 , obo:RO_0002213 .

obo:RO_0002630 a rdf:Property ;
  rdfs:label "directly negatively regulates" ;
  rdfs:comment "p directly negatively regulates q iff p is immediately causally upstream of q, and p negatively regulates q." ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002578 , obo:RO_0002212 .

obo:RO_0004031 a rdf:Property ;
  rdfs:label "enables subfunction" ;
  rdfs:comment "Holds between an entity and an process P where the entity enables some larger compound process, and that larger process has-part P." ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002328 .

obo:RO_0004032 a rdf:Property ;
  rdfs:label "acts upstream of or within, positive effect" ;
  rdfs:seeAlso <http://wiki.geneontology.org/index.php/Acts_upstream_of_or_within,_positive_effect> ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002264 .

obo:RO_0004033 a rdf:Property ;
  rdfs:label "acts upstream of or within, negative effect" ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002264 .

obo:RO_0004034 a rdf:Property ;
  rdfs:label "acts upstream of, positive effect" ;
  rdfs:comment "c 'acts upstream of, positive effect' p if c is enables f, and f is causally upstream of p, and the direction of f is positive" ;
  rdfs:seeAlso <http://wiki.geneontology.org/index.php/Acts_upstream_of,_positive_effect> ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0004032 , obo:RO_0002263 .

obo:RO_0004035 a rdf:Property ;
  rdfs:label "acts upstream of, negative effect" ;
  rdfs:comment "c 'acts upstream of, negative effect' p if c is enables f, and f is causally upstream of p, and the direction of f is negative" ;
  rdfs:seeAlso <http://wiki.geneontology.org/index.php/Acts_upstream_of,_negative_effect> ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0004033 , obo:RO_0002263 .

obo:RO_0004046 a rdf:Property ;
  rdfs:label "causally upstream of or within, negative effect" ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002418 .

obo:RO_0004047 a rdf:Property ;
  rdfs:label "causally upstream of or within, positive effect" ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002418 .

obo:RO_0012011 a rdf:Property ;
  rdfs:label "indirectly causally upstream of"@en ;
  rdfs:comment "p is indirectly causally upstream of q iff p is causally upstream of q and there exists some process r such that p is causally upstream of r and r is causally upstream of q." ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0002411 .

obo:RO_0012012 a rdf:Property ;
  rdfs:label "indirectly regulates"@en ;
  rdfs:comment "p indirectly regulates q iff p is indirectly causally upstream of q and p regulates q." ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0012011 , obo:RO_0002211 .

obo:RO_0017001 a rdf:Property ;
  rdfs:label "device utilizes material"@en ;
  rdfs:comment "X device utilizes material Y means X and Y are material entities, and X is capable of some process P that has input Y." ;
  rdfs:range <https://w3id.org/linkml/Any> .

obo:RO_0019001 a rdf:Property ;
  rdfs:label "positively regulates characteristic" ;
  rdfs:comment "A relationship that holds between a process and a characteristic in which process (P) positively regulates characteristic (C) iff: P results in an increase in the intensity or magnitude of C." ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0019000 .

obo:RO_0019002 a rdf:Property ;
  rdfs:label "negatively regulates characteristic" ;
  rdfs:comment "A relationship that holds between a process and a characteristic in which process (P) negatively regulates characteristic (C) iff: P results in a decrease in the intensity or magnitude of C." ;
  rdfs:range xsd:string ;
  rdfs:subPropertyOf obo:RO_0019000 .

obo:SDDO_3000001 a rdf:Property ;
  rdfs:label "provideInformationOn"@en ;
  rdfs:range <https://w3id.org/linkml/Any> .

obo:SDDO_3000004 a rdf:Property ;
  rdfs:label "providesAccessTo"@en ;
  rdfs:range <https://w3id.org/linkml/Any> .

obo:SDDO_3000006 a rdf:Property ;
  rdfs:label "consistOf"@en ;
  rdfs:range <https://w3id.org/linkml/Any> .

obo:SDDO_3000019 a rdf:Property ;
  rdfs:label "leadTo"@en ;
  rdfs:range <https://w3id.org/linkml/Any> .

obo:SDDO_3000027 a rdf:Property ;
  rdfs:label "contain"@en ;
  rdfs:range <https://w3id.org/linkml/Any> .

obo:SDDO_3000030 a rdf:Property ;
  rdfs:label "sameAs"@en ;
  rdfs:range <https://w3id.org/linkml/Any> .

obo:SDDO_3000033 a rdf:Property ;
  rdfs:label "aggregate"@en ;
  rdfs:range <https://w3id.org/linkml/Any> .

obo:SDDO_3000035 a rdf:Property ;
  rdfs:label "characterizedBy"@en ;
  rdfs:range <https://w3id.org/linkml/Any> .

obo:SDDO_3000041 a rdf:Property ;
  rdfs:label "quantifiedBy"@en ;
  rdfs:range <https://w3id.org/linkml/Any> .

<http://purl.obolibrary.org/obo/ro/subsets#ro-eco> a rdf:Property ;
  rdfs:range xsd:string .

obo:valid_for_go_annotation_extension a rdf:Property ;
  rdfs:range xsd:string .

obo:valid_for_go_gp2term a rdf:Property ;
  rdfs:range xsd:string .

obo:valid_for_go_ontology a rdf:Property ;
  rdfs:range xsd:string .

obo:valid_for_gocam a rdf:Property ;
  rdfs:range xsd:string .

obo:OBI_0002310 a rdfs:Class ;
  rdfs:label "pathologic distant metastases stage for ovary according to AJCC 7th edition" ;
  rdfs:comment "A categorical value specification that is a  pathologic finding about one or more characteristics of ovarian cancer following the rules of the TNM AJCC v7 classification system as they pertain to distant metastases. TNM pathologic distant metastasis findings are based on clinical findings supplemented by histopathologic examination of one or more tissue specimens acquired during surgery." ;
  rdfs:subClassOf obo:OBI_0001930 .

obo:OBI_0002311 a obo:OBI_0002310 ;
  rdfs:label "cM0 (ovary)" ;
  rdfs:comment "A pathologic distant metastases stage for ovary according to AJCC 7th edition indicating that there is no distant metastasis." .

obo:OBI_0002312 a obo:OBI_0002310 ;
  rdfs:label "cM1 (ovary)" ;
  rdfs:comment "A pathologic distant metastases stage for ovary according to AJCC 7th edition indicating that there is distant metastasis except peritoneal metastasis based on clinical assessment." .

obo:OBI_0002313 a obo:OBI_0002310 ;
  rdfs:label "pM1 (ovary)" ;
  rdfs:comment "A pathologic distant metastases stage for ovary according to AJCC 7th edition indicating that there is distant metastasis except peritoneal metastasis that is histologically confirmed." .

obo:OBI_0002314 a rdfs:Class ;
  rdfs:label "clinical tumor stage group according to AJCC 7th edition" ;
  rdfs:comment "A categorical value specification that is an assessment of the stage of a cancer according to the American Joint Committee on Cancer (AJCC) v7 staging systems." ;
  rdfs:subClassOf obo:OBI_0001930 .

obo:OBI_0002315 a obo:OBI_0002314 ;
  rdfs:label "Occult Carcinoma (AJCC 7th)" ;
  rdfs:comment "A clinical tumor stage group according to AJCC 7th edition indicating a small carcinoma, either asymptomatic or giving rise to metastases without symptoms due to the primary carcinoma." .

obo:OBI_0002316 a obo:OBI_0002314 ;
  rdfs:label "Stage 0 (AJCC 7th)" ;
  rdfs:comment "A clinical tumor stage group according to AJCC 7th edition indicating a carcinoma in situ (or melanoma in situ for melanoma of the skin or germ cell neoplasia in situ for testicular germ cell tumors) and generally is considered to have no metastatic potential." .

obo:OBI_0002317 a obo:OBI_0002314 ;
  rdfs:label "Stage I (AJCC 7th)" ;
  rdfs:comment "A clinical tumor stage group according to AJCC 7th edition indicating cancers that are smaller or less deeply invasive without regional disease or nodes." .

obo:OBI_0002318 a obo:OBI_0002314 ;
  rdfs:label "Stage IIA (AJCC 7th)" ;
  rdfs:comment "A clinical tumor stage group according to AJCC 7th edition indicating cancers with increasing tumor or nodal extent but less than in Stage III and with differing characteristics from IIB and IIC." .

obo:OBI_0002319 a obo:OBI_0002314 ;
  rdfs:label "Stage IIB (AJCC 7th)" ;
  rdfs:comment "A clinical tumor stage group according to AJCC 7th edition indicating cancers with increasing tumor or nodal extent but less than in Stage III and with differing characteristics from IIA and IIC." .

obo:OBI_0002320 a obo:OBI_0002314 ;
  rdfs:label "Stage IIC (AJCC 7th)" ;
  rdfs:comment "A clinical tumor stage group according to AJCC 7th edition indicating cancers with increasing tumor or nodal extent but less than in Stage III and with differing characteristics from IIA and IIB." .

obo:OBI_0002321 a obo:OBI_0002314 ;
  rdfs:label "Stage IIIA (AJCC 7th)" ;
  rdfs:comment "A clinical tumor stage group according to AJCC 7th edition indicating cancers with increasing tumor or nodal extent greater than in Stage II and with differing characteristics from IIIB and IIIC." .

obo:OBI_0002322 a obo:OBI_0002314 ;
  rdfs:label "Stage IIIB (AJCC 7th)" ;
  rdfs:comment "A clinical tumor stage group according to AJCC 7th edition indicating cancers with increasing tumor or nodal extent greater than in Stage II and with differing characteristics from IIIA and IIIC." .

obo:OBI_0002323 a obo:OBI_0002314 ;
  rdfs:label "Stage IIIC (AJCC 7th)" ;
  rdfs:comment "A clinical tumor stage group according to AJCC 7th edition indicating cancers with increasing tumor or nodal extent greater than in Stage II and with differing characteristics from IIIA and IIIB." .

obo:OBI_0002324 a obo:OBI_0002314 ;
  rdfs:label "Stage IVA (AJCC 7th)" ;
  rdfs:comment "A clinical tumor stage group according to AJCC 7th edition indicating cancers in patients who present with distant metastases at diagnosis and with differing characteristics from IVB." .

obo:OBI_0002325 a obo:OBI_0002314 ;
  rdfs:label "Stage IVB (AJCC 7th)" ;
  rdfs:comment "A clinical tumor stage group according to AJCC 7th edition indicating cancers in patients who present with distant metastases at diagnosis and with differing characteristics from IVA." .

obo:UO_0000051 a rdfs:Class ;
  rdfs:label "concentration unit" ;
  rdfs:subClassOf obo:IAO_0000003 .

obo:UO_0000062 a obo:UO_0000051 ;
  rdfs:label "molar" ;
  rdfs:comment "A unit of concentration which expresses a concentration of 1 mole of solute per liter of solution (mol/L)." .

obo:UO_0000063 a obo:UO_0000051 ;
  rdfs:label "millimolar" ;
  rdfs:comment "A unit of molarity which is equal to one thousandth of a molar or 10^[-3] M." .

obo:UO_0000064 a obo:UO_0000051 ;
  rdfs:label "micromolar" ;
  rdfs:comment "A unit of molarity which is equal to one millionth of a molar or 10^[-6] M." .

obo:UO_0000065 a obo:UO_0000051 ;
  rdfs:label "nanomolar" ;
  rdfs:comment "A unit of molarity which is equal to one thousandth of one millionth of a molar or 10^[-9] M." .

obo:UO_0000066 a obo:UO_0000051 ;
  rdfs:label "picomolar" ;
  rdfs:comment "A unit of molarity which is equal to 10^[-12] M." .

obo:UO_0000163 a obo:UO_0000051 ;
  rdfs:label "mass percentage" ;
  rdfs:comment "A dimensionless concentration unit which denotes the mass of a substance in a mixture as a percentage of the mass of the entire mixture." .

obo:UO_0000164 a obo:UO_0000051 ;
  rdfs:label "mass volume percentage" ;
  rdfs:comment "A dimensionless concentration unit which denotes the mass of the substance in a mixture as a percentage of the volume of the entire mixture." .

obo:UO_0000165 a obo:UO_0000051 ;
  rdfs:label "volume percentage" ;
  rdfs:comment "A dimensionless concentration unit which denotes the volume of the solute in mL per 100 mL of the resulting solution." .

obo:UO_0000175 a obo:UO_0000051 ;
  rdfs:label "gram per liter" ;
  rdfs:comment "A mass unit density which is equal to mass of an object in grams divided by the volume in liters." .

obo:UO_0000176 a obo:UO_0000051 ;
  rdfs:label "milligram per milliliter" ;
  rdfs:comment "A mass unit density which is equal to mass of an object in milligrams divided by the volume in milliliters." .

obo:UO_0000196 a obo:UO_0000051 ;
  rdfs:label "pH" ;
  rdfs:comment "A dimensionless concentration notation which denotes the acidity of a solution in terms of activity of hydrogen ions (H+)." .

obo:UO_0000207 a obo:UO_0000051 ;
  rdfs:label "milliliter per liter" ;
  rdfs:comment "A volume per unit volume unit which is equal to one millionth of a liter of solute in one liter of solution." .

obo:UO_0000208 a obo:UO_0000051 ;
  rdfs:label "gram per deciliter" ;
  rdfs:comment "A mass density unit which is equal to mass of an object in grams divided by the volume in deciliters." .

obo:UO_0000212 a obo:UO_0000051 ;
  rdfs:label "colony forming unit per volume" ;
  rdfs:comment "A concentration unit which a measure of viable bacterial numbers in a given volume." .

obo:UO_0000301 a obo:UO_0000051 ;
  rdfs:label "microgram per liter" ;
  rdfs:comment "A mass unit density which is equal to mass of an object in micrograms divided by the volume in liters." .

obo:OBI_0002341 a rdfs:Class ;
  rdfs:label "International Federation of Gynecology and Obstetrics ovarian cancer stage value specification" ;
  rdfs:comment "A categorical value specification that is a pathologic finding about one or more characteristics of ovarian cancer following the rules of the FIGO classification system." ;
  rdfs:subClassOf obo:OBI_0001930 .

obo:OBI_0002342 a obo:OBI_0002341 ;
  rdfs:label "Stage 1 (FIGO)" ;
  rdfs:comment "A International Federation of Gynecology and Obstetrics ovarian cancer stage value specification associated with TNM stage values of T1, N0, and M0." .

obo:OBI_0002343 a obo:OBI_0002341 ;
  rdfs:label "Stage 1A (FIGO)" ;
  rdfs:comment "A International Federation of Gynecology and Obstetrics ovarian cancer stage value specification associated with TNM stage values of T1a, N0, and M0." .

obo:OBI_0002344 a obo:OBI_0002341 ;
  rdfs:label "Stage 1B (FIGO)" ;
  rdfs:comment "A International Federation of Gynecology and Obstetrics ovarian cancer stage value specification associated with TNM stage values of T1b, N0, and M0." .

obo:OBI_0002345 a obo:OBI_0002341 ;
  rdfs:label "Stage 1C (FIGO)" ;
  rdfs:comment "A International Federation of Gynecology and Obstetrics ovarian cancer stage value specification associated with TNM stage values of T1c, N0, and M0." .

obo:OBI_0002346 a obo:OBI_0002341 ;
  rdfs:label "Stage 2 (FIGO)" ;
  rdfs:comment "A International Federation of Gynecology and Obstetrics ovarian cancer stage value specification associated with TNM stage values of T2, N0, and M0." .

obo:OBI_0002347 a obo:OBI_0002341 ;
  rdfs:label "Stage 2A (FIGO)" ;
  rdfs:comment "A International Federation of Gynecology and Obstetrics ovarian cancer stage value specification associated with TNM stage values of T2a, N0, and M0." .

obo:OBI_0002348 a obo:OBI_0002341 ;
  rdfs:label "Stage 2B (FIGO)" ;
  rdfs:comment "A International Federation of Gynecology and Obstetrics ovarian cancer stage value specification associated with TNM stage values of T2b, N0, and M0." .

obo:OBI_0002349 a obo:OBI_0002341 ;
  rdfs:label "Stage 2C (FIGO)" ;
  rdfs:comment "A International Federation of Gynecology and Obstetrics ovarian cancer stage value specification associated with TNM stage values of T2c, N0, and M0." .

obo:OBI_0002350 a obo:OBI_0002341 ;
  rdfs:label "Stage 3 (FIGO)" ;
  rdfs:comment "A International Federation of Gynecology and Obstetrics ovarian cancer stage value specification associated with TNM stage values of (T3, N0, and M0) or (T3,3a,3b, NX, and M0)." .

obo:OBI_0002351 a obo:OBI_0002341 ;
  rdfs:label "Stage 3A (FIGO)" ;
  rdfs:comment "A International Federation of Gynecology and Obstetrics ovarian cancer stage value specification associated with TNM stage values of T3a, N0, and M0 ." .

obo:OBI_0002352 a obo:OBI_0002341 ;
  rdfs:label "Stage 3B (FIGO)" ;
  rdfs:comment "A International Federation of Gynecology and Obstetrics ovarian cancer stage value specification associated with TNM stage values of T3b, N0, and M0 ." .

obo:OBI_0002353 a obo:OBI_0002341 ;
  rdfs:label "Stage 3C (FIGO)" ;
  rdfs:comment "A International Federation of Gynecology and Obstetrics ovarian cancer stage value specification associated with TNM stage values of (T3c, N0,X and M0) or (any T, N1 and M0)." .

obo:OBI_0002354 a obo:OBI_0002341 ;
  rdfs:label "Stage 4 (FIGO)" ;
  rdfs:comment "A International Federation of Gynecology and Obstetrics ovarian cancer stage value specification associated with TNM stage values of any T, any N, and M1." .

obo:OBI_0002355 a obo:OBI_0002341 ;
  rdfs:label "Stage Unknown (FIGO)" ;
  rdfs:comment "A International Federation of Gynecology and Obstetrics ovarian cancer stage value specification associated with TNM stage values of (T0, N0, and M0) or (T1,1a-1c,2,2a-2c, NX, and M0) or (TX, N0,X, M0)." .

obo:OBI_0002287 a rdfs:Class ;
  rdfs:label "pathologic lymph node stage for ovary according to AJCC 7th edition" ;
  rdfs:comment "A categorical value specification that is a pathologic finding about one or more characteristics of ovarian cancer following the rules of the TNM AJCC v7 classification system as they pertain to staging of regional lymph nodes." ;
  rdfs:subClassOf obo:OBI_0001930 .

obo:OBI_0002288 a obo:OBI_0002287 ;
  rdfs:label "pN0 (ovary)" ;
  rdfs:comment "A pathologic lymph node stage for ovary according to AJCC 7th edition indicating that there is no regional lymph node metastasis." .

obo:OBI_0002289 a obo:OBI_0002287 ;
  rdfs:label "pN1 (ovary)" ;
  rdfs:comment "A pathologic lymph node stage for ovary according to AJCC 7th edition indicating that there is regional lymph node metastasis." .

obo:UO_0000105 a rdfs:Class ;
  rdfs:label "frequency unit" ;
  rdfs:subClassOf obo:IAO_0000003 .

obo:UO_0000106 a obo:UO_0000105 ;
  rdfs:label "hertz" ;
  rdfs:comment "A frequency unit which is equal to 1 complete cycle of a recurring phenomenon in 1 second." .

obo:OBI_0002224 a rdfs:Class ;
  rdfs:label "pathologic primary tumor stage for colon and rectum according to AJCC 7th edition" ;
  rdfs:comment "A categorical value specification that is a pathologic finding about one or more characteristics of colorectal cancer following the rules of the TNM American Joint Committee on Cancer (AJCC) version 7 classification system as they pertain to staging of the primary tumor. TNM pathologic primary tumor findings are based on clinical findings supplemented by histopathologic examination of one or more tissue specimens acquired during surgery." ;
  rdfs:subClassOf obo:OBI_0001930 .

obo:OBI_0002225 a obo:OBI_0002224 ;
  rdfs:label "pT0 (colon)" ;
  rdfs:comment "A pathologic primary tumor stage for colon and rectum according to AJCC 7th edition indicating that there is no evidence of primary tumor." .

obo:OBI_0002226 a obo:OBI_0002224 ;
  rdfs:label "pTis (colon)" ;
  rdfs:comment "A pathologic primary tumor stage for colon and rectum according to AJCC 7th edition indicating carcinoma in situ (intraepithelial or invasion of lamina propria)." .

obo:OBI_0002227 a obo:OBI_0002224 ;
  rdfs:label "pT1 (colon)" ;
  rdfs:comment "A pathologic primary tumor stage for colon and rectum according to AJCC 7th edition indicating that the tumor invades submucosa." .

obo:OBI_0002228 a obo:OBI_0002224 ;
  rdfs:label "pT2 (colon)" ;
  rdfs:comment "A pathologic primary tumor stage for colon and rectum according to AJCC 7th edition indicating that the tumor invades muscularis propria." .

obo:OBI_0002229 a obo:OBI_0002224 ;
  rdfs:label "pT3 (colon)" ;
  rdfs:comment "A pathologic primary tumor stage for colon and rectum according to AJCC 7th edition indicating that the tumor invades subserosa or into non-peritionealized pericolic or perirectal tissues." .

obo:OBI_0002230 a obo:OBI_0002224 ;
  rdfs:label "pT4a (colon)" ;
  rdfs:comment "A pathologic primary tumor stage for colon and rectum according to AJCC 7th edition indicating that the tumor perforates visceral peritoneum." .

obo:OBI_0002231 a obo:OBI_0002224 ;
  rdfs:label "pT4b (colon)" ;
  rdfs:comment "A pathologic primary tumor stage for colon and rectum according to AJCC 7th edition indicating that the tumor directly invades other organs or structures." .

obo:OBI_0002357 a rdfs:Class ;
  rdfs:label "Eastern Cooperative Oncology Group score value specification" ;
  rdfs:comment "A performance status value specification designed by the Eastern Cooperative Oncology Group to assess disease progression and its affect on the daily living abilities of the patient." ;
  rdfs:subClassOf obo:OBI_0002356 .

obo:OBI_0002358 a obo:OBI_0002357 ;
  rdfs:label "3: symptomatic in bed more than 50% of the day but not bed ridden" ;
  rdfs:comment "An Eastern Cooperative Oncology Group score value specification indicating a patient is symptomatic and in bed for more than 50% of the day but is not bed ridden." .

obo:OBI_0002359 a obo:OBI_0002357 ;
  rdfs:label "2: symptomatic but in bed less than 50% of the day" ;
  rdfs:comment "An Eastern Cooperative Oncology Group score value specification indicating a patient is symptomatic but is in bed for less than 50% of the day." .

obo:OBI_0002360 a obo:OBI_0002357 ;
  rdfs:label "4: bed ridden" ;
  rdfs:comment "An Eastern Cooperative Oncology Group score value specification indicating a patient is symptomatic and is bed ridden." .

obo:OBI_0002361 a obo:OBI_0002357 ;
  rdfs:label "0: asymptomatic" ;
  rdfs:comment "An Eastern Cooperative Oncology Group score value specification indicating a patient is asymptomatic." .

obo:OBI_0002362 a obo:OBI_0002357 ;
  rdfs:label "1: symptomatic but fully ambulatory" ;
  rdfs:comment "An Eastern Cooperative Oncology Group score value specification indicating a patient is symptomatic but is fully ambulatory." .

obo:OBI_0002290 a rdfs:Class ;
  rdfs:label "pathologic distant metastases stage for colon according to AJCC 7th edition" ;
  rdfs:comment "A categorical value specification that is a pathologic finding about one or more characteristics of colon cancer following the rules of the TNM AJCC v7 classification system as they pertain to distant metastases. TNM pathologic distant metastasis findings are based on clinical findings supplemented by histopathologic examination of one or more tissue specimens acquired during surgery." ;
  rdfs:subClassOf obo:OBI_0001930 .

obo:OBI_0002291 a obo:OBI_0002290 ;
  rdfs:label "cM0 (colon)" ;
  rdfs:comment "A pathologic distant metastases stage for colon according to AJCC 7th edition indicating that there are no symptoms or signs of distant metastasis." .

obo:OBI_0002292 a obo:OBI_0002290 ;
  rdfs:label "cM1 (colon)" ;
  rdfs:comment "A pathologic distant metastases stage for colon according to AJCC 7th edition indicating that there is clinical evidence of distant metastases by history, physical examination, imaging studies, or invasive procedures, but without microscopic evidence of the presumed distant metastases." .

obo:OBI_0002293 a obo:OBI_0002290 ;
  rdfs:label "cM1a (colon)" ;
  rdfs:comment "A pathologic distant metastases stage for colon according to AJCC 7th edition indicating that metastasis is confined to one organ based on clinical assessment." .

obo:OBI_0002294 a obo:OBI_0002290 ;
  rdfs:label "cM1b (colon)" ;
  rdfs:comment "A pathologic distant metastases stage for colon according to AJCC 7th edition indicating that metastasis is in more than one organ or the peritoneum based on clinical assessment." .

obo:OBI_0002295 a obo:OBI_0002290 ;
  rdfs:label "pM1 (colon)" ;
  rdfs:comment "A pathologic distant metastases stage for colon according to AJCC 7th edition indicating that there is microscopic evidence confirming distant metastatic disease." .

obo:OBI_0002296 a obo:OBI_0002290 ;
  rdfs:label "pM1a (colon)" ;
  rdfs:comment "A pathologic distant metastases stage for colon according to AJCC 7th edition indicating that metastasis is confined to one organ and histologically confirmed." .

obo:OBI_0002297 a obo:OBI_0002290 ;
  rdfs:label "pM1b (colon)" ;
  rdfs:comment "A pathologic distant metastases stage for colon according to AJCC 7th edition indicating that metastasis is in more than one organ or the peritoneum and histologically confirmed." .

obo:UO_0000005 a rdfs:Class ;
  rdfs:label "temperature unit" ;
  rdfs:subClassOf obo:IAO_0000003 .

obo:UO_0000027 a obo:UO_0000005 ;
  rdfs:label "degree Celsius" ;
  rdfs:comment "A temperature unit which is equal to one kelvin degree. However, they have their zeros at different points. The centigrade scale has its zero at 273.15 K." .

obo:UO_0000195 a obo:UO_0000005 ;
  rdfs:label "degree Fahrenheit" ;
  rdfs:comment "A temperature unit which is equal to 5/9ths of a kelvin. Negative 40 degrees Fahrenheit is equal to negative 40 degrees Celsius." .

obo:OBI_0000963 a rdfs:Class ;
  rdfs:label "categorical label" ;
  rdfs:comment "A label that is part of a categorical datum and that indicates the value of the data item on the categorical scale." ;
  rdfs:subClassOf obo:IAO_0000009 .

obo:OBI_0000958 a obo:OBI_0000963 ;
  rdfs:label "right handed" .

obo:OBI_0000979 a obo:OBI_0000963 ;
  rdfs:label "ambidexterous" .

obo:OBI_0000998 a obo:OBI_0000963 ;
  rdfs:label "left handed" .

obo:OBI_0002279 a rdfs:Class ;
  rdfs:label "pathologic lymph node stage for lung according to AJCC 7th edition" ;
  rdfs:comment "A categorical value specification that is a pathologic finding about one or more characteristics of lung cancer following the rules of the TNM AJCC v7 classification system as they pertain to staging of regional lymph nodes." ;
  rdfs:subClassOf obo:OBI_0001930 .

obo:OBI_0002280 a obo:OBI_0002279 ;
  rdfs:label "pN0 (lung)" ;
  rdfs:comment "A pathologic lymph node stage for lung according to AJCC 7th edition indicating no regional lymph node metastasis." .

obo:OBI_0002281 a obo:OBI_0002279 ;
  rdfs:label "pN1 (lung)" ;
  rdfs:comment "A pathologic lymph node stage for lung according to AJCC 7th edition indicating metastasis in ipsilateral peribronchial and/or ipsilateral hilar lymph nodes and intrapulmonary nodes, including involvement by direct extension." .

obo:OBI_0002282 a obo:OBI_0002279 ;
  rdfs:label "pN2 (lung)" ;
  rdfs:comment "A pathologic lymph node stage for lung according to AJCC 7th edition indicating metastasis in ipsilateral mediastinal and/or subcarinal lymph node(s)." .

obo:OBI_0002283 a obo:OBI_0002279 ;
  rdfs:label "pN3 (lung)" ;
  rdfs:comment "A pathologic lymph node stage for lung according to AJCC 7th edition indicating metastasis in contralateral mediastinal, contralateral hilar, ipsilateral or contralateral scalene, or supraclavicular lymph node(s)." .

obo:OBI_0002219 a rdfs:Class ;
  rdfs:label "histologic grade for ovarian tumor according to the World Health Organization" ;
  rdfs:comment "A histologic grade for ovarian tumor that is from a histological classification by the World Health Organization (WHO)." ;
  rdfs:subClassOf obo:OBI_0002215 .

obo:OBI_0002220 a obo:OBI_0002219 ;
  rdfs:label "G1 (WHO)" ;
  rdfs:comment "A histologic grade for ovarian tumor according to the World Health Organization indicating that the tumor is well differentiated." .

obo:OBI_0002221 a obo:OBI_0002219 ;
  rdfs:label "G2 (WHO)" ;
  rdfs:comment "A histologic grade for ovarian tumor according to the World Health Organization indicating that the tumor is moderately differentiated." .

obo:OBI_0002222 a obo:OBI_0002219 ;
  rdfs:label "G3 (WHO)" ;
  rdfs:comment "A histologic grade for ovarian tumor according to the World Health Organization indicating that the tumor is poorly differentiated." .

obo:OBI_0002223 a obo:OBI_0002219 ;
  rdfs:label "G4 (WHO)" ;
  rdfs:comment "A histologic grade for ovarian tumor according to the World Health Organization indicating that the tumor is undifferentiated." .

obo:OBI_0002306 a rdfs:Class ;
  rdfs:label "pathologic distant metastases stage for kidney according to AJCC 7th edition" ;
  rdfs:comment "A categorical value specification that is a pathologic finding about one or more characteristics of renal cancer following the rules of the TNM AJCC v7 classification system as they pertain to distant metastases. TNM pathologic distant metastasis findings are based on clinical findings supplemented by histopathologic examination of one or more tissue specimens acquired during surgery." ;
  rdfs:subClassOf obo:OBI_0001930 .

obo:OBI_0002307 a obo:OBI_0002306 ;
  rdfs:label "cM0 (kidney)" ;
  rdfs:comment "A pathologic distant metastases stage for kidney according to AJCC 7th edition indicating that there is no distant metastasis." .

obo:OBI_0002308 a obo:OBI_0002306 ;
  rdfs:label "cM1 (kidney)" ;
  rdfs:comment "A pathologic distant metastases stage for kidney according to AJCC 7th edition indicating that there are distant metastases based on clinical assessment." .

obo:OBI_0002309 a obo:OBI_0002306 ;
  rdfs:label "pM1 (kidney)" ;
  rdfs:comment "A pathologic distant metastases stage for kidney according to AJCC 7th edition indicating that there is a distant metastases that is histologically confirmed." .

obo:OBI_0002243 a rdfs:Class ;
  rdfs:label "pathologic primary tumor stage for kidney according to AJCC 7th edition" ;
  rdfs:comment "A categorical value specification that is a pathologic finding about one or more characteristics of renal cancer following the rules of the TNM AJCC v7 classification system as they pertain to staging of the primary tumor. TNM pathologic primary tumor findings are based on clinical findings supplemented by histopathologic examination of one or more tissue specimens acquired during surgery." ;
  rdfs:subClassOf obo:OBI_0001930 .

obo:OBI_0002244 a obo:OBI_0002243 ;
  rdfs:label "pT0 (kidney)" ;
  rdfs:comment "A pathologic primary tumor stage for kidney according to AJCC 7th edition indicating that there is no evidence of primary tumor." .

obo:OBI_0002245 a obo:OBI_0002243 ;
  rdfs:label "pT1 (kidney)" ;
  rdfs:comment "A pathologic primary tumor stage for kidney according to AJCC 7th edition indicating that the tumor is 7 cm or less in greatest dimension and limited to the kidney." .

obo:OBI_0002246 a obo:OBI_0002243 ;
  rdfs:label "pT1a (kidney)" ;
  rdfs:comment "A pathologic primary tumor stage for kidney according to AJCC 7th edition indicating that the tumor is 4 cm or less." .

obo:OBI_0002247 a obo:OBI_0002243 ;
  rdfs:label "pT1b (kidney)" ;
  rdfs:comment "A pathologic primary tumor stage for kidney according to AJCC 7th edition indicating that the tumor is more than 4 cm but not more than 7 cm." .

obo:OBI_0002248 a obo:OBI_0002243 ;
  rdfs:label "pT2 (kidney)" ;
  rdfs:comment "A pathologic primary tumor stage for kidney according to AJCC 7th edition indicating that the tumor is more than 7 cm in greatest dimension and limited to the kidney." .

obo:OBI_0002249 a obo:OBI_0002243 ;
  rdfs:label "pT2a (kidney)" ;
  rdfs:comment "A pathologic primary tumor stage for kidney according to AJCC 7th edition indicating that the tumor is more than 7 cm but not more than 10 cm." .

obo:OBI_0002250 a obo:OBI_0002243 ;
  rdfs:label "pT2b (kidney)" ;
  rdfs:comment "A pathologic primary tumor stage for kidney according to AJCC 7th edition indicating that the tumor is more than 10 cm and limited to the kidney." .

obo:OBI_0002251 a obo:OBI_0002243 ;
  rdfs:label "pT3 (kidney)" ;
  rdfs:comment "A pathologic primary tumor stage for kidney according to AJCC 7th edition indicating that the tumor extends into major veins or perinephric tissues but not into the ipsilateral adrenal gland and not beyond the Gerota fascia." .

obo:OBI_0002252 a obo:OBI_0002243 ;
  rdfs:label "pT3a (kidney)" ;
  rdfs:comment "A pathologic primary tumor stage for kidney according to AJCC 7th edition indicating that the tumor grossly extends into the renal vein or its segmental (muscle containing) branches, or the tumor invades perirenal and/or renal sinus fat (peripelvic) fat but not beyond Gerota fascia." .

obo:OBI_0002253 a obo:OBI_0002243 ;
  rdfs:label "pT3b (kidney)" ;
  rdfs:comment "A pathologic primary tumor stage for kidney according to AJCC 7th edition indicating that the tumor grossly extends into vena cava below diaphragm." .

obo:OBI_0002254 a obo:OBI_0002243 ;
  rdfs:label "pT3c (kidney)" ;
  rdfs:comment "A pathologic primary tumor stage for kidney according to AJCC 7th edition indicating that the tumor grossly extends into vena cava above the diaphragm or Invades the wall of the vena cava." .

obo:OBI_0002255 a obo:OBI_0002243 ;
  rdfs:label "pT4 (kidney)" ;
  rdfs:comment "A pathologic primary tumor stage for kidney according to AJCC 7th edition indicating that the tumor invades beyond Gerota fascia (including contiguous extension into the ipsilateral adrenal gland)." .

obo:UO_0000280 a rdfs:Class ;
  rdfs:label "rate unit" ;
  rdfs:subClassOf obo:IAO_0000003 .

obo:UO_0000281 a obo:UO_0000280 ;
  rdfs:label "count per nanomolar second" ;
  rdfs:comment "A rate unit which is equal to one over one nanomolar second." .

obo:UO_0000282 a obo:UO_0000280 ;
  rdfs:label "count per molar second" ;
  rdfs:comment "A rate unit which is equal to one over one molar second." .

obo:UO_0000284 a obo:UO_0000280 ;
  rdfs:label "count per nanomolar" ;
  rdfs:comment "A rate unit which is equal to one over one nanomolar." .

obo:UO_0000285 a obo:UO_0000280 ;
  rdfs:label "count per molar" ;
  rdfs:comment "A rate unit which is equal to one over one molar." .

obo:UO_0000006 a rdfs:Class ;
  rdfs:label "substance unit" ;
  rdfs:subClassOf obo:IAO_0000003 .

obo:UO_0000039 a obo:UO_0000006 ;
  rdfs:label "micromole" ;
  rdfs:comment "A substance unit equal to a millionth of a mol or 10^[-6] mol." .

obo:UO_0000041 a obo:UO_0000006 ;
  rdfs:label "nanomole" ;
  rdfs:comment "A substance unit equal to one thousandth of one millionth of a mole or 10^[-9] mol." .

obo:UO_0000042 a obo:UO_0000006 ;
  rdfs:label "picomole" ;
  rdfs:comment "A substance unit equal to 10^[-12] mol." .

obo:IAO_0000409 a rdfs:Class ;
  rdfs:label "denotator type"@en ;
  rdfs:comment "A denotator type indicates how a term should be interpreted from an ontological perspective."@en ;
  rdfs:subClassOf obo:IAO_0000102 .

obo:IAO_0000410 a obo:IAO_0000409 ;
  rdfs:label "universal"@en .

obo:IAO_0000420 a obo:IAO_0000409 ;
  rdfs:label "defined class"@en ;
  rdfs:comment "A defined class is a class that is defined by a set of logically necessary and sufficient conditions but is not a universal"@en .

obo:IAO_0000421 a obo:IAO_0000409 ;
  rdfs:label "named class expression"@en ;
  rdfs:comment "A named class expression is a logical expression that is given a name. The name can be used in place of the expression."@en .

obo:OBI_0002216 a rdfs:Class ;
  rdfs:label "histologic grade for ovarian tumor according to a two-tier grading system" ;
  rdfs:comment "A histologic grade for ovarian tumor that is from a two-tier histological classification of tumors." ;
  rdfs:subClassOf obo:OBI_0002215 .

obo:OBI_0002217 a obo:OBI_0002216 ;
  rdfs:label "Low grade ovarian tumor" ;
  rdfs:comment "A histologic grade for ovarian tumor according to a two-tier grading system indicating that the tumor is low grade." .

obo:OBI_0002218 a obo:OBI_0002216 ;
  rdfs:label "High grade ovarian tumor" ;
  rdfs:comment "A histologic grade for ovarian tumor according to a two-tier grading system indicating that the tumor is high grade." .

obo:OBI_0000713 a rdfs:Class ;
  rdfs:label "GenePattern software" ;
  rdfs:comment "a software that provides access to more than 100 tools for gene expression analysis, proteomics, SNP analysis and common data processing tasks." ;
  rdfs:subClassOf obo:IAO_0000010 .

obo:OBI_0000761 a obo:OBI_0000713 ;
  rdfs:label "GenePattern module SVM" ;
  rdfs:comment "GenePattern module SVM is a GenePattern software module which is used to run a support vector machine data transformation." .

obo:OBI_0000766 a obo:OBI_0000713 ;
  rdfs:label "GenePattern module KMeansClustering" ;
  rdfs:comment "GenePattern module KMeansClustering is a GenePattern software module which is used to perform a k Means clustering data transformation." .

obo:OBI_0000768 a obo:OBI_0000713 ;
  rdfs:label "GenePattern module CARTXValidation" ;
  rdfs:comment "GenePattern module CARTXValidation is a GenePattern software module which uses a CART decision tree induction with a leave one out cross validation data transformations." .

obo:OBI_0000771 a obo:OBI_0000713 ;
  rdfs:label "GenePattern module KNNXValidation" ;
  rdfs:comment "GenePattern module KNNXValidation is a GenePattern software module which uses a k-nearest neighbours clustering with a leave one out cross validation data transformations." .

obo:OBI_0000772 a obo:OBI_0000713 ;
  rdfs:label "GenePattern module PeakMatch" .

obo:OBI_0000773 a obo:OBI_0000713 ;
  rdfs:label "GenePattern module KNN" ;
  rdfs:comment "GenePattern module KNN is a GenePattern software module which perform a k-nearest neighbors data transformation." .

obo:OBI_0000774 a obo:OBI_0000713 ;
  rdfs:label "GenePattern module HierarchicalClustering" ;
  rdfs:comment "GenePattern module HierarchicalClustering is a GenePattern software module which is used to perform a hierarchical clustering data transformation." .

obo:OBI_0000777 a obo:OBI_0000713 ;
  rdfs:label "GenePattern module PCA" ;
  rdfs:comment "GenePattern module PCA is a GenePattern software module which is used to perform a principal components analysis dimensionality reduction data transformation." .

obo:OBI_0000782 a obo:OBI_0000713 ;
  rdfs:label "GenePattern module HeatMapViewer" ;
  rdfs:comment "A GenePattern software module which is used to generate a heatmap view of data." .

obo:OBI_0000783 a obo:OBI_0000713 ;
  rdfs:label "GenePattern module HierarchicalClusteringViewer" ;
  rdfs:comment "A GenePattern software module which is used to generate a view of data that has been hierarchically clustered." .

obo:OBI_0002205 a rdfs:Class ;
  rdfs:label "histologic grade according to AJCC 7th edition" ;
  rdfs:comment "A categorical value specification that is a histologic grade assigned to a tumor slide specimen according to the American Joint Committee on Cancer (AJCC) 7th Edition grading system." ;
  rdfs:subClassOf obo:OBI_0001930 .

obo:OBI_0002206 a obo:OBI_0002205 ;
  rdfs:label "G1: Well differentiated" ;
  rdfs:comment "A histologic grade according to AJCC 7th edition indicating that the tumor cells and the organization of the tumor tissue appear close to normal." .

obo:OBI_0002207 a obo:OBI_0002205 ;
  rdfs:label "G2: Moderately differentiated" ;
  rdfs:comment "A histologic grade according to AJCC 7th edition indicating that the tumor cells are moderately differentiated and reflect an intermediate grade." .

obo:OBI_0002208 a obo:OBI_0002205 ;
  rdfs:label "G3: Poorly differentiated" ;
  rdfs:comment "A histologic grade according to AJCC 7th edition indicating that the tumor cells are poorly differentiated and do not look like normal cells and tissue." .

obo:OBI_0002209 a obo:OBI_0002205 ;
  rdfs:label "G4: Undifferentiated" ;
  rdfs:comment "A histologic grade according to AJCC 7th edition indicating that the tumor cells are undifferentiated and do not look like normal cells and tissue." .

obo:UO_0000003 a rdfs:Class ;
  rdfs:label "time unit" ;
  rdfs:comment "A unit which is a standard measure of the dimension in which events occur in sequence." ;
  rdfs:subClassOf obo:IAO_0000003 .

obo:UO_0000010 a obo:UO_0000003 ;
  rdfs:label "second" ;
  rdfs:comment "A time unit which is equal to the duration of 9 192 631 770 periods of the radiation corresponding to the transition between the two hyperfine levels of the ground state of the caesium 133 atom." .

obo:UO_0000031 a obo:UO_0000003 ;
  rdfs:label "minute" ;
  rdfs:comment "A time unit which is equal to 60 seconds." .

obo:UO_0000032 a obo:UO_0000003 ;
  rdfs:label "hour" ;
  rdfs:comment "A time unit which is equal to 3600 seconds or 60 minutes." .

obo:UO_0000033 a obo:UO_0000003 ;
  rdfs:label "day" ;
  rdfs:comment "A time unit which is equal to 24 hours." .

obo:UO_0000034 a obo:UO_0000003 ;
  rdfs:label "week" ;
  rdfs:comment "A time unit which is equal to 7 days." .

obo:UO_0000035 a obo:UO_0000003 ;
  rdfs:label "month" ;
  rdfs:comment "A time unit which is approximately equal to the length of time of one of cycle of the moon's phases which in science is taken to be equal to 30 days." .

obo:UO_0000036 a obo:UO_0000003 ;
  rdfs:label "year" ;
  rdfs:comment "A time unit which is equal to 12 months which is science is taken to be equal to 365.25 days." .

obo:OBI_0002270 a rdfs:Class ;
  rdfs:label "pathologic lymph node stage for colon and rectum according to AJCC 7th edition" ;
  rdfs:comment "A categorical value specification that is a pathologic finding about one or more characteristics of colorectal cancer following the rules of the TNM AJCC v7 classification system as they pertain to staging of regional lymph nodes." ;
  rdfs:subClassOf obo:OBI_0001930 .

obo:OBI_0002271 a obo:OBI_0002270 ;
  rdfs:label "pN0 (colon)" ;
  rdfs:comment "A pathologic lymph node stage for colon and rectum according to AJCC 7th edition indicating no regional lymph node metastsis." .

obo:OBI_0002272 a obo:OBI_0002270 ;
  rdfs:label "pN1 (colon)" ;
  rdfs:comment "A pathologic lymph node stage for colon and rectum according to AJCC 7th edition indicating metastasis in 1-3 regional lymph nodes." .

obo:OBI_0002273 a obo:OBI_0002270 ;
  rdfs:label "pN1a (colon)" ;
  rdfs:comment "A pathologic lymph node stage for colon and rectum according to AJCC 7th edition indicating metastasis in 1 regional lymph node." .

obo:OBI_0002274 a obo:OBI_0002270 ;
  rdfs:label "pN1b (colon)" ;
  rdfs:comment "A pathologic lymph node stage for colon and rectum according to AJCC 7th edition indicating metastasis in 2-3 regional lymph nodes." .

obo:OBI_0002275 a obo:OBI_0002270 ;
  rdfs:label "pN1c (colon)" ;
  rdfs:comment "A pathologic lymph node stage for colon and rectum according to AJCC 7th edition indicating tumor deposit(s), i.e., satellites in the subserosa, or in non-peritonealized pericolic or perirectal soft tissue without regional lymph node metastasis." .

obo:OBI_0002276 a obo:OBI_0002270 ;
  rdfs:label "pN2 (colon)" ;
  rdfs:comment "A pathologic lymph node stage for colon and rectum according to AJCC 7th edition indicating metastasis in 4 or more regional lymph nodes." .

obo:OBI_0002277 a obo:OBI_0002270 ;
  rdfs:label "pN2a (colon)" ;
  rdfs:comment "A pathologic lymph node stage for colon and rectum according to AJCC 7th edition indicating metastasis in 4 to 6 regional lymph nodes." .

obo:OBI_0002278 a obo:OBI_0002270 ;
  rdfs:label "pN2b (colon)" ;
  rdfs:comment "A pathologic lymph node stage for colon and rectum according to AJCC 7th edition indicating metastasis in 7 or more regional lymph nodes." .

obo:IAO_0000098 a rdfs:Class ;
  rdfs:label "data format specification"@en ;
  rdfs:comment """A data format specification is the information content borne by the document published defining the specification.
Example: The ISO document specifying what encompasses an XML document; The instructions in a XSD file"""@en ;
  rdfs:subClassOf obo:IAO_0000033 .

obo:OBI_0000317 a obo:IAO_0000098 ;
  rdfs:label "Transformation-ML"@en ;
  rdfs:comment "Transformation-ML is a format standard of a digital entity that is conformant with the Transformation-ML standard.(http://wiki.ficcs.org/ficcs/Transformation-ML?action=AttachFile&do=get&target=Transformation-ML_v1.0.26.pdf)"@en .

obo:OBI_0000321 a obo:IAO_0000098 ;
  rdfs:label "ACS"@en ;
  rdfs:comment "ACS is a format standard of a digital entity that is conformant with the Analytical Cytometry Standard. (http://www.isac-net.org/content/view/607/150/)"@en .

obo:OBI_0000322 a obo:IAO_0000098 ;
  rdfs:label "XML"@en ;
  rdfs:comment "XML is a format standard of a digital entity that is conformant with the W3C Extensible Markup Language Recommendation.(http://www.w3.org/XML/)"@en .

obo:OBI_0000324 a obo:IAO_0000098 ;
  rdfs:label "RDF"@en ;
  rdfs:comment "RDF is a format standard of a digital entity that is conformant with the W3C Resource Description Framework RDF/XML Syntax specification.(http://www.w3.org/RDF/)"@en .

obo:OBI_0000325 a obo:IAO_0000098 ;
  rdfs:label "zip"@en ;
  rdfs:comment "zip is a format standard of a digital entity that is conformant with the PKWARE .ZIP file format specification  (http://www.pkware.com/index.php?option=com_content&task=view&id=59&Itemid=103/)"@en .

obo:OBI_0000326 a obo:IAO_0000098 ;
  rdfs:label "tar"@en ;
  rdfs:comment "tar is a format standard of a digital entity that is conformant with the tape archive file format as standardized by POSIX.1-1998, POSIX.1-2001, or any other tar format compliant with the GNU tar specification. (http://www.gnu.org/software/tar/manual/)"@en .

obo:OBI_0000327 a obo:IAO_0000098 ;
  rdfs:label "FCS"@en ;
  rdfs:comment "FCS is a format standard of a digital entity that is conformant with the Flow Cytometry Data File Standard.(http://www.fcspress.com/)"@en .

obo:OBI_0000329 a obo:IAO_0000098 ;
  rdfs:label "Compensation-ML"@en ;
  rdfs:comment "Compensation-ML is a format standard of a digital entity that is conformant with the Compensation-ML standard. (http://wiki.ficcs.org/ficcs/Compensation-ML?action=AttachFile&do=get&target=Compensation-ML_v1.0.24.pdf)"@en .

obo:OBI_0000330 a obo:IAO_0000098 ;
  rdfs:label "Gating-ML"@en ;
  rdfs:comment "Gating-ML is a format standard of a digital entity that is conformant with the Gating-ML standard. (http://www.flowcyt.org/gating/)"@en .

obo:OBI_0000332 a obo:IAO_0000098 ;
  rdfs:label "OWL"@en ;
  rdfs:comment "OWL is a format standard of a digital entity that is conformant with the W3C Web Ontology Language specification.(http://www.w3.org/2004/OWL/)"@en .

obo:OBI_0002298 a rdfs:Class ;
  rdfs:label "pathologic distant metastases stage for lung according to AJCC 7th edition" ;
  rdfs:comment "A categorical value specification that is a pathologic finding about one or more characteristics of lung cancer following the rules of the TNM AJCC v7 classification system as they pertain to distant metastases. TNM pathologic distant metastasis findings are based on clinical findings supplemented by histopathologic examination of one or more tissue specimens acquired during surgery." ;
  rdfs:subClassOf obo:OBI_0001930 .

obo:OBI_0002299 a obo:OBI_0002298 ;
  rdfs:label "cM0 (lung)" ;
  rdfs:comment "A pathologic distant metastases stage for lung according to AJCC 7th edition indicating that there is no distant metastasis." .

obo:OBI_0002300 a obo:OBI_0002298 ;
  rdfs:label "cM1 (lung)" ;
  rdfs:comment "A pathologic distant metastases stage for lung according to AJCC 7th edition indicating that there are distant metastases based on clinical assessment." .

obo:OBI_0002301 a obo:OBI_0002298 ;
  rdfs:label "cM1a (lung)" ;
  rdfs:comment "A pathologic distant metastases stage for lung according to AJCC 7th edition indicating that metastasis is based on clinical assessment and a separate tumor nodule(s) in a contralateral lobe; tumor with pleural nodules OR malignant pleural or pericardial effusion." .

obo:OBI_0002302 a obo:OBI_0002298 ;
  rdfs:label "cM1b (lung)" ;
  rdfs:comment "A pathologic distant metastases stage for lung according to AJCC 7th edition indicating that there is a distant metastases based on clinical assessment." .

obo:OBI_0002303 a obo:OBI_0002298 ;
  rdfs:label "pM1 (lung)" ;
  rdfs:comment "A pathologic distant metastases stage for lung according to AJCC 7th edition indicating that there is a distant metastases that is histologically confirmed." .

obo:OBI_0002304 a obo:OBI_0002298 ;
  rdfs:label "pM1a (lung)" ;
  rdfs:comment "A pathologic distant metastases stage for lung according to AJCC 7th edition indicating that metastasis is histologically confirmed and a separate tumor nodule(s) in a contralateral lobe; tumor with pleural nodules OR malignant pleural or pericardial effusion." .

obo:OBI_0002305 a obo:OBI_0002298 ;
  rdfs:label "pM1b (lung)" ;
  rdfs:comment "A pathologic distant metastases stage for lung according to AJCC 7th edition indicating that there is a distant metastases that is histologically confirmed and associated with distant lymph nodes or carcinomatosis." .

obo:UO_0000095 a rdfs:Class ;
  rdfs:label "volume unit" ;
  rdfs:subClassOf obo:IAO_0000003 .

obo:UO_0000097 a obo:UO_0000095 ;
  rdfs:label "cubic centimeter" ;
  rdfs:comment "A volume unit which is equal to one millionth of a cubic meter or 10^[-9] m^[3], or to 1 ml." .

obo:UO_0000098 a obo:UO_0000095 ;
  rdfs:label "milliliter" ;
  rdfs:comment "A volume unit which is equal to one thousandth of a liter or 10^[-3] L, or to 1 cubic centimeter." .

obo:UO_0000099 a obo:UO_0000095 ;
  rdfs:label "liter" ;
  rdfs:comment "A volume unit which is equal to one thousandth of a cubic meter or 10^[-3] m^[3], or to 1 decimeter." .

obo:UO_0000100 a obo:UO_0000095 ;
  rdfs:label "cubic decimeter" ;
  rdfs:comment "A volume unit which is equal to one thousand of a cubic meter or 10^[-3] m^[3], or to 1 L." .

obo:UO_0000101 a obo:UO_0000095 ;
  rdfs:label "microliter" ;
  rdfs:comment "A volume unit which is equal to one millionth of a liter or 10^[-6] L." .

obo:UO_0000102 a obo:UO_0000095 ;
  rdfs:label "nanoliter" ;
  rdfs:comment "A volume unit which is equal to one thousandth of one millionth of a liter or 10^[-9] L." .

obo:UO_0000103 a obo:UO_0000095 ;
  rdfs:label "picoliter" ;
  rdfs:comment "A volume unit which is equal to 10^[-12] L." .

obo:OBI_0001000 a rdfs:Class ;
  rdfs:label "questionnaire" ;
  rdfs:comment "A document with a set of printed or written questions with a choice of answers, devised for the purposes of a survey or statistical study."@en ;
  rdfs:subClassOf obo:IAO_0000310 .

obo:OBI_0001004 a obo:OBI_0001000 ;
  rdfs:label "Edingburgh handedness inventory" ;
  rdfs:comment "The Edinburgh Handedness Inventory is a set of questions used to assess the dominance of a person's right or left hand in everyday activities."@en .

obo:UO_0000001 a rdfs:Class ;
  rdfs:label "length unit" ;
  rdfs:comment "A unit which is a standard measure of the distance between two points." ;
  rdfs:subClassOf obo:IAO_0000003 .

obo:UO_0000008 a obo:UO_0000001 ;
  rdfs:label "meter" ;
  rdfs:comment "A length unit which is equal to the length of the path traveled by light in vacuum during a time interval of 1/299 792 458 of a second." .

obo:UO_0000015 a obo:UO_0000001 ;
  rdfs:label "centimeter" ;
  rdfs:comment "A length unit which is equal to one hundredth of a meter or 10^[-2] m." .

obo:UO_0000016 a obo:UO_0000001 ;
  rdfs:label "millimeter" ;
  rdfs:comment "A length unit which is equal to one thousandth of a meter or 10^[-3] m." .

obo:UO_0000017 a obo:UO_0000001 ;
  rdfs:label "micrometer" ;
  rdfs:comment "A length unit which is equal to one millionth of a meter or 10^[-6] m." .

obo:UO_0000018 a obo:UO_0000001 ;
  rdfs:label "nanometer" ;
  rdfs:comment "A length unit which is equal to one thousandth of one millionth of a meter or 10^[-9] m." .

obo:UO_0000019 a obo:UO_0000001 ;
  rdfs:label "angstrom" ;
  rdfs:comment "A length unit which is equal to 10 [-10] m." .

obo:OBI_0200051 a rdfs:Class ;
  rdfs:label "principal components analysis dimensionality reduction"@en ;
  rdfs:comment "A principal components analysis dimensionality reduction is a dimensionality reduction achieved by applying principal components analysis and by keeping low-order principal components and excluding higher-order ones."@en ;
  rdfs:subClassOf obo:OBI_0200050 .

obo:OBI_0000760 a obo:OBI_0200051 ;
  rdfs:label "GenePattern PCA" .

obo:OBI_0002326 a rdfs:Class ;
  rdfs:label "International Federation of Gynecology and Obstetrics cervical cancer stage value specification" ;
  rdfs:comment "A categorical value specification that is an assessment of the stage of a gynecologic cancer according to the International Federation of Gynecology and Obstetrics (FIGO) staging systems." ;
  rdfs:subClassOf obo:OBI_0001930 .

obo:OBI_0002327 a obo:OBI_0002326 ;
  rdfs:label "Stage IA (FIGO)" ;
  rdfs:comment "An International Federation of Gynecology and Obstetrics cervical cancer stage value specification indicating invasive carcinoma which can be diagnosed only by microscopy, with deepest invasion <5 mm and the largest extension <7 mm." .

obo:OBI_0002328 a obo:OBI_0002326 ;
  rdfs:label "Stage IA1 (FIGO)" ;
  rdfs:comment "An International Federation of Gynecology and Obstetrics cervical cancer stage value specification indicating measured stromal invasion of <3.0 mm in depth and extension of <7.0 mm." .

obo:OBI_0002329 a obo:OBI_0002326 ;
  rdfs:label "Stage IA2 (FIGO)" ;
  rdfs:comment "An International Federation of Gynecology and Obstetrics cervical cancer stage value specification indicating measured stromal invasion of >3.0 mm and not >5.0 mm with an extension of not >7.0 mm." .

obo:OBI_0002330 a obo:OBI_0002326 ;
  rdfs:label "Stage IB (FIGO)" ;
  rdfs:comment "An International Federation of Gynecology and Obstetrics cervical cancer stage value specification indicating clinically visible lesions limited to the cervix uteri or pre-clinical cancers greater than stage IA" .

obo:OBI_0002331 a obo:OBI_0002326 ;
  rdfs:label "Stage IB1 (FIGO)" ;
  rdfs:comment "An International Federation of Gynecology and Obstetrics cervical cancer stage value specification indicating clinically visible lesion limited to the cervix uteri or pre-clinical cancers greater than stage IA <4.0 cm in greatest dimension." .

obo:OBI_0002332 a obo:OBI_0002326 ;
  rdfs:label "Stage IB2 (FIGO)" ;
  rdfs:comment "An International Federation of Gynecology and Obstetrics cervical cancer stage value specification indicating clinically visible lesion limited to the cervix uteri or pre-clinical cancers greater than stage IA >4.0 cm in greatest dimension." .

obo:OBI_0002333 a obo:OBI_0002326 ;
  rdfs:label "Stage IIA (FIGO)" ;
  rdfs:comment "An International Federation of Gynecology and Obstetrics cervical cancer stage value specification indicating cervical carcinoma invades beyond the uterus, but not to the pelvic wall or to the lower third of the vagina without parametrial invasion." .

obo:OBI_0002334 a obo:OBI_0002326 ;
  rdfs:label "Stage IIA1 (FIGO)" ;
  rdfs:comment "An International Federation of Gynecology and Obstetrics cervical cancer stage value specification indicating cervical carcinoma invades beyond the uterus, but not to the pelvic wall or to the lower third of the vagina without parametrial invasion and clinically visible lesion <4.0 cm in greatest dimension." .

obo:OBI_0002335 a obo:OBI_0002326 ;
  rdfs:label "Stage IIA2 (FIGO)" ;
  rdfs:comment "An International Federation of Gynecology and Obstetrics cervical cancer stage value specification indicating cervical carcinoma invades beyond the uterus, but not to the pelvic wall or to the lower third of the vagina without parametrial invasion and clinically visible lesion >4.0 cm in greatest dimension." .

obo:OBI_0002336 a obo:OBI_0002326 ;
  rdfs:label "Stage IIB (FIGO)" ;
  rdfs:comment "An International Federation of Gynecology and Obstetrics cervical cancer stage value specification indicating cervical carcinoma invades beyond the uterus, but not to the pelvic wall or to the lower third of the vagina with obvious parametrial invasion." .

obo:OBI_0002337 a obo:OBI_0002326 ;
  rdfs:label "Stage IIIA (FIGO)" ;
  rdfs:comment "An International Federation of Gynecology and Obstetrics cervical cancer stage value specification indicating tumour involves lower third of the vagina, with no extension to the pelvic wall." .

obo:OBI_0002338 a obo:OBI_0002326 ;
  rdfs:label "Stage IIIB (FIGO)" ;
  rdfs:comment "An International Federation of Gynecology and Obstetrics cervical cancer stage value specification indicating extension to the pelvic wall and/or hydronephrosis or non-functioning kidney." .

obo:OBI_0002339 a obo:OBI_0002326 ;
  rdfs:label "Stage IVA (FIGO)" ;
  rdfs:comment "An International Federation of Gynecology and Obstetrics cervical cancer stage value specification indicating spread of the growth to adjacent organs." .

obo:OBI_0002340 a obo:OBI_0002326 ;
  rdfs:label "Stage IVB (FIGO)" ;
  rdfs:comment "An International Federation of Gynecology and Obstetrics cervical cancer stage value specification indicating spread to distant organs." .

obo:OBI_0002284 a rdfs:Class ;
  rdfs:label "pathologic lymph node stage for kidney according to AJCC 7th edition" ;
  rdfs:comment "A categorical value specification that is a pathologic finding about one or more characteristics of renal cancer following the rules of the TNM AJCC v7 classification system as they pertain to staging of regional lymph nodes." ;
  rdfs:subClassOf obo:OBI_0001930 .

obo:OBI_0002285 a obo:OBI_0002284 ;
  rdfs:label "pN0 (kidney)" ;
  rdfs:comment "A pathologic lymph node stage for kidney according to AJCC 7th edition indicating that there is no regional lymph node metastasis." .

obo:OBI_0002286 a obo:OBI_0002284 ;
  rdfs:label "pN1 (kidney)" ;
  rdfs:comment "A pathologic lymph node stage for kidney according to AJCC 7th edition indicating that there is regional lymph node metastasis." .

obo:OBI_0000726 a rdfs:Class ;
  rdfs:label "peak matching" ;
  rdfs:comment "Peak matching is a data transformation performed on a dataset of a graph of ordered data points (e.g. a spectrum) with the objective of pattern matching local maxima above a noise threshold" ;
  rdfs:subClassOf obo:OBI_0200000 .

obo:OBI_0000778 a obo:OBI_0000726 ;
  rdfs:label "GenePattern peak matching" .

obo:OBI_0002363 a rdfs:Class ;
  rdfs:label "Karnofsky score vaue specification" ;
  rdfs:comment "A performance status value specification designed for classifying patients 16 years of age or older by their functional impairment." ;
  rdfs:subClassOf obo:OBI_0002356 .

obo:OBI_0002364 a obo:OBI_0002363 ;
  rdfs:label "100: asymptomatic" ;
  rdfs:comment "A Karnofsky score vaue specification indicating that a patient is asymptomatic." .

obo:OBI_0002365 a obo:OBI_0002363 ;
  rdfs:label "80-90: symptomatic but fully ambulatory" ;
  rdfs:comment "A Karnofsky score vaue specification indicating that a patient is symptomatic but fully ambulatory." .

obo:OBI_0002366 a obo:OBI_0002363 ;
  rdfs:label "60-70: symptomatic but in bed less than 50% of the day" ;
  rdfs:comment "A Karnofsky score vaue specification indicating that a patient is symptomatic but in bed less than 50% of the day." .

obo:OBI_0002367 a obo:OBI_0002363 ;
  rdfs:label "40-50: symptomatic, in bed more than 50% of the day, but not bed ridden" ;
  rdfs:comment "A Karnofsky score vaue specification indicating that a patient is symptomatic, in bed more than 50% of the day, but not bed ridden." .

obo:UO_0000270 a rdfs:Class ;
  rdfs:label "volumetric flow rate unit" ;
  rdfs:subClassOf obo:IAO_0000003 .

obo:UO_0000271 a obo:UO_0000270 ;
  rdfs:label "microliters per minute" ;
  rdfs:comment "A volumetric flow rate unit which is equal to one microliter volume through a given surface in one minute." .

obo:OBI_0000749 a rdfs:Class ;
  rdfs:label "CART"@en ;
  rdfs:comment "A CART (classification and regression trees) is a data transformation method for producing a classification or regression model with a tree-based structure."@en ;
  rdfs:subClassOf obo:OBI_0000707 .

obo:OBI_0000767 a obo:OBI_0000749 ;
  rdfs:label "GenePattern CART" .

obo:OBI_0002210 a rdfs:Class ;
  rdfs:label "histologic grade according to the Fuhrman Nuclear Grading System" ;
  rdfs:comment "A categorical value specification that is a histologic grade assigned to a tumor slide specimen according to the Fuhrman Nuclear Grading System." ;
  rdfs:subClassOf obo:OBI_0001930 .

obo:OBI_0002211 a obo:OBI_0002210 ;
  rdfs:label "G1 (Fuhrman)" ;
  rdfs:comment "A histologic grade according to the Fuhrman Nuclear Grading System indicating that nuclei are round, uniform, approximately 10um and that nucleoli are inconspicuous or absent." .

obo:OBI_0002212 a obo:OBI_0002210 ;
  rdfs:label "G2 (Fuhrman)" ;
  rdfs:comment "A histologic grade according to the Fuhrman Nuclear Grading System indicating that nuclei are slightly irregular, approximately 15um and nucleoli are evident." .

obo:OBI_0002213 a obo:OBI_0002210 ;
  rdfs:label "G3 (Fuhrman)" ;
  rdfs:comment "A histologic grade according to the Fuhrman Nuclear Grading System indicating that nuclei are very irregular, approximately 20um and nucleoli large and prominent." .

obo:OBI_0002214 a obo:OBI_0002210 ;
  rdfs:label "G4 (Fuhrman)" ;
  rdfs:comment "A histologic grade according to the Fuhrman Nuclear Grading System indicating that nuclei arei bizarre and multilobulated, 20um or greater and nucleoli are prominent and chromatin clumped." .

obo:UO_0000002 a rdfs:Class ;
  rdfs:label "mass unit" ;
  rdfs:comment "A unit which is a standard measure of the amount of matter/energy of a physical object." ;
  rdfs:subClassOf obo:IAO_0000003 .

obo:UO_0000009 a obo:UO_0000002 ;
  rdfs:label "kilogram" ;
  rdfs:comment "A mass unit which is equal to the mass of the International Prototype Kilogram kept by the BIPM at Svres, France." .

obo:UO_0000021 a obo:UO_0000002 ;
  rdfs:label "gram" ;
  rdfs:comment "A mass unit which is equal to one thousandth of a kilogram or 10^[-3] kg." .

obo:UO_0000022 a obo:UO_0000002 ;
  rdfs:label "milligram" ;
  rdfs:comment "A mass unit which is equal to one thousandth of a gram or 10^[-3] g." .

obo:UO_0000023 a obo:UO_0000002 ;
  rdfs:label "microgram" ;
  rdfs:comment "A mass unit which is equal to one millionth of a gram or 10^[-6] g." .

obo:UO_0000024 a obo:UO_0000002 ;
  rdfs:label "nanogram" ;
  rdfs:comment "A mass unit which is equal to one thousandth of one millionth of a gram or 10^[-9] g." .

obo:UO_0000025 a obo:UO_0000002 ;
  rdfs:label "picogram" ;
  rdfs:comment "A mass unit which is equal to 10^[-12] g." .

obo:OBI_0200033 a rdfs:Class ;
  rdfs:label "leave one out cross validation method"@en ;
  rdfs:comment "is a data transformation :  leave-one-out cross-validation (LOOCV) involves using a single observation from the original sample as the validation data, and the remaining observations as the training data. This is repeated such that each observation in the sample is used once as the validation data" ;
  rdfs:subClassOf obo:OBI_0000792 .

obo:OBI_0000763 a obo:OBI_0200033 ;
  rdfs:label "GenePattern LOOCV" .

obo:IAO_0000225 a rdfs:Class ;
  rdfs:label "obsolescence reason specification"@en ;
  rdfs:comment "The reason for which a term has been deprecated. The allowed values come from an enumerated list of predefined terms. See the specification of these instances for more detailed definitions of each enumerated value."@en ;
  rdfs:subClassOf obo:IAO_0000102 .

obo:IAO_0000103 a obo:IAO_0000225 ;
  rdfs:label "failed exploratory term"@en ;
  rdfs:comment "The term was used in an attempt to structure part of the ontology but in retrospect failed to do a good job"@en .

obo:IAO_0000226 a obo:IAO_0000225 ;
  rdfs:label "placeholder removed"@en .

obo:IAO_0000227 a obo:IAO_0000225 ;
  rdfs:label "terms merged"@en .

obo:IAO_0000228 a obo:IAO_0000225 ;
  rdfs:label "term imported"@en .

obo:IAO_0000229 a obo:IAO_0000225 ;
  rdfs:label "term split"@en .

obo:IAO_0000078 a rdfs:Class ;
  rdfs:label "curation status specification"@en ;
  rdfs:comment "The curation status of the term. The allowed values come from an enumerated list of predefined terms. See the specification of these instances for more detailed definitions of each enumerated value."@en ;
  rdfs:subClassOf obo:IAO_0000102 .

obo:IAO_0000002 a obo:IAO_0000078 ;
  rdfs:label "example to be eventually removed"@en .

obo:IAO_0000120 a obo:IAO_0000078 ;
  rdfs:label "metadata complete"@en ;
  rdfs:comment "Class has all its metadata, but is either not guaranteed to be in its final location in the asserted IS_A hierarchy or refers to another class that is not complete."@en .

obo:IAO_0000121 a obo:IAO_0000078 ;
  rdfs:label "organizational term"@en ;
  rdfs:comment "Term created to ease viewing/sort terms for development purpose, and will not be included in a release"@en .

obo:IAO_0000122 a obo:IAO_0000078 ;
  rdfs:label "ready for release"@en ;
  rdfs:comment "Class has undergone final review, is ready for use, and will be included in the next release. Any class lacking \"ready_for_release\" should be considered likely to change place in hierarchy, have its definition refined, or be obsoleted in the next release.  Those classes deemed \"ready_for_release\" will also derived from a chain of ancestor classes that are also \"ready_for_release.\""@en .

obo:IAO_0000123 a obo:IAO_0000078 ;
  rdfs:label "metadata incomplete"@en ;
  rdfs:comment "Class is being worked on; however, the metadata (including definition) are not complete or sufficiently clear to the branch editors."@en .

obo:IAO_0000124 a obo:IAO_0000078 ;
  rdfs:label "uncurated"@en ;
  rdfs:comment "Nothing done yet beyond assigning a unique class ID and proposing a preferred term."@en .

obo:IAO_0000125 a obo:IAO_0000078 ;
  rdfs:label "pending final vetting"@en ;
  rdfs:comment "All definitions, placement in the asserted IS_A hierarchy and required minimal metadata are complete. The class is awaiting a final review by someone other than the term editor."@en .

obo:IAO_0000423 a obo:IAO_0000078 ;
  rdfs:label "to be replaced with external ontology term"@en ;
  rdfs:comment "Terms with this status should eventually replaced with a term from another ontology."@en .

obo:IAO_0000428 a obo:IAO_0000078 ;
  rdfs:label "requires discussion"@en ;
  rdfs:comment "A term that is metadata complete, has been reviewed, and problems have been identified that require discussion before release. Such a term requires editor note(s) to identify the outstanding issues."@en .

obo:OBI_0002256 a rdfs:Class ;
  rdfs:label "pathologic primary tumor stage for ovary according to AJCC 7th edition" ;
  rdfs:comment "A categorical value specification that is a pathologic finding about one or more characteristics of ovarian cancer following the rules of the TNM AJCC v7 classification system as they pertain to staging of the primary tumor. TNM pathologic primary tumor findings are based on clinical findings supplemented by histopathologic examination of one or more tissue specimens acquired during surgery." ;
  rdfs:subClassOf obo:OBI_0001930 .

obo:OBI_0002257 a obo:OBI_0002256 ;
  rdfs:label "pT0 (ovary)" ;
  rdfs:comment "A pathologic primary tumor stage for ovary according to AJCC 7th edition indicating that there is no evidence of primary tumor." .

obo:OBI_0002258 a obo:OBI_0002256 ;
  rdfs:label "pT1 (ovary)" ;
  rdfs:comment "A pathologic primary tumor stage for ovary according to AJCC 7th edition indicating that the tumor is limited to the ovaries (one or both)." .

obo:OBI_0002259 a obo:OBI_0002256 ;
  rdfs:label "pT1a (ovary)" ;
  rdfs:comment "A pathologic primary tumor stage for ovary according to AJCC 7th edition indicating that the tumor is limited to one ovary; capsule intact, no tumor on ovarian surface and no malignant cells in ascites or peritoneal washings." .

obo:OBI_0002260 a obo:OBI_0002256 ;
  rdfs:label "pT1b (ovary)" ;
  rdfs:comment "A pathologic primary tumor stage for ovary according to AJCC 7th edition indicating that the tumor is limited to both ovaries; capsule intact, no tumor on ovarian surface and no malignant cells in ascites or peritoneal washings." .

obo:OBI_0002261 a obo:OBI_0002256 ;
  rdfs:label "pT1c (ovary)" ;
  rdfs:comment "A pathologic primary tumor stage for ovary according to AJCC 7th edition indicating that the tumor is limited to one or both ovaries with capsule ruptured, tumor on ovarian surface, or malignant cells in ascites or peritoneal washings." .

obo:OBI_0002262 a obo:OBI_0002256 ;
  rdfs:label "pT2 (ovary)" ;
  rdfs:comment "A pathologic primary tumor stage for ovary according to AJCC 7th edition indicating that the tumor involves one or both ovaries with pelvic extension." .

obo:OBI_0002263 a obo:OBI_0002256 ;
  rdfs:label "pT2a (ovary)" ;
  rdfs:comment "A pathologic primary tumor stage for ovary according to AJCC 7th edition indicating that the tumor has extension and/or implants on uterus and/or tube(s) and no malignant cells in ascites or peritoneal washings." .

obo:OBI_0002264 a obo:OBI_0002256 ;
  rdfs:label "pT2b (ovary)" ;
  rdfs:comment "A pathologic primary tumor stage for ovary according to AJCC 7th edition indicating that the tumor has extension to other pelvic tissues and no malignant cells in ascites or peritoneal washings." .

obo:OBI_0002265 a obo:OBI_0002256 ;
  rdfs:label "pT2c (ovary)" ;
  rdfs:comment "A pathologic primary tumor stage for ovary according to AJCC 7th edition indicating that the tumor has pelvic extension with malignant cells in ascites or peritoneal washings." .

obo:OBI_0002266 a obo:OBI_0002256 ;
  rdfs:label "pT3 (ovary)" ;
  rdfs:comment "A pathologic primary tumor stage for ovary according to AJCC 7th edition indicating that the tumor involves one or both ovaries with microscopically confirmed peritoneal metastasis outside the pelvis and/or regional lymph node metastasis." .

obo:OBI_0002267 a obo:OBI_0002256 ;
  rdfs:label "pT3a (ovary)" ;
  rdfs:comment "A pathologic primary tumor stage for ovary according to AJCC 7th edition indicating that the tumor has microscopic peritoneal metastasis beyond pelvis." .

obo:OBI_0002268 a obo:OBI_0002256 ;
  rdfs:label "pT3b (ovary)" ;
  rdfs:comment "A pathologic primary tumor stage for ovary according to AJCC 7th edition indicating that the tumor has macroscopic peritoneal, metastatasis beyond pelvis, 2 cm or less in greatest dimension." .

obo:OBI_0002269 a obo:OBI_0002256 ;
  rdfs:label "pT3c (ovary)" ;
  rdfs:comment "A pathologic primary tumor stage for ovary according to AJCC 7th edition indicating that the tumor has peritoneal metastasis beyond pelvis, more than 2 cm in greatest dimension and/or regional lymph node metastasis." .

obo:OBI_0002232 a rdfs:Class ;
  rdfs:label "pathologic primary tumor stage for lung according to AJCC 7th edition" ;
  rdfs:comment "A categorical value specification that is a pathologic finding about one or more characteristics of lung cancer following the rules of the TNM American Joint Committee on Cancer (AJCC) version 7 classification system as they pertain to staging of the primary tumor. TNM pathologic primary tumor findings are based on clinical findings supplemented by histopathologic examination of one or more tissue specimens acquired during surgery." ;
  rdfs:subClassOf obo:OBI_0001930 .

obo:OBI_0002233 a obo:OBI_0002232 ;
  rdfs:label "pT0 (lung)" ;
  rdfs:comment "A pathologic primary tumor stage for lung according to AJCC 7th edition indicating that there is no evidence of primary tumor." .

obo:OBI_0002234 a obo:OBI_0002232 ;
  rdfs:label "pTis (lung)" ;
  rdfs:comment "A pathologic primary tumor stage for lung according to AJCC 7th edition indicating carcinoma in situ." .

obo:OBI_0002235 a obo:OBI_0002232 ;
  rdfs:label "pT1 (lung)" ;
  rdfs:comment "A pathologic primary tumor stage for lung according to AJCC 7th edition indicating that the tumor is 3 cm or less in greatest dimension, surrounded by lung or visceral pleura without bronchoscopic evidence of invasion more proximal than the lobar bronchus (i.e., not in the main bronchus)." .

obo:OBI_0002236 a obo:OBI_0002232 ;
  rdfs:label "pT1a (lung)" ;
  rdfs:comment "A pathologic primary tumor stage for lung according to AJCC 7th edition indicating that the tumor is 2 cm or less in greatest dimension." .

obo:OBI_0002237 a obo:OBI_0002232 ;
  rdfs:label "pT1b (lung)" ;
  rdfs:comment "A pathologic primary tumor stage for lung according to AJCC 7th edition indicating that the tumor is more than 2 cm but not more than 3 cm in greatest dimension." .

obo:OBI_0002238 a obo:OBI_0002232 ;
  rdfs:label "pT2 (lung)" ;
  rdfs:comment "A pathologic primary tumor stage for lung according to AJCC 7th edition indicating that the tumor is more than 3 cm but not more than 7 cm or the tumor has any of the following features: involves main bronchus, 2 cm or more distal to the carina, invades visceral pleura, associated with atelectasis or obstructive pneumonitis that extends to the hilar region but does not involve the entire lung." .

obo:OBI_0002239 a obo:OBI_0002232 ;
  rdfs:label "pT2a (lung)" ;
  rdfs:comment "A pathologic primary tumor stage for lung according to AJCC 7th edition indicating that the tumor is more than 3 cm but not more than 5 cm in greatest dimension." .

obo:OBI_0002240 a obo:OBI_0002232 ;
  rdfs:label "pT2b (lung)" ;
  rdfs:comment "A pathologic primary tumor stage for lung according to AJCC 7th edition indicating that the tumor is more than 5 cm but not more than 7 cm in greatest dimension." .

obo:OBI_0002241 a obo:OBI_0002232 ;
  rdfs:label "pT3 (lung)" ;
  rdfs:comment "A pathologic primary tumor stage for lung according to AJCC 7th edition indicating that the tumor is more than 7 cm or one that directly invades any of: parietal pleura, chest wall (including superior sulcus tumors), diaphragm, phrenic nerve, mediastinal pleura, parietal pericardiu or the tumor is in the main bronchus less than 2 cm distal to the carina but without  involvement of the carina or there is associated atelectasis or obstructive pneumonitis of the entire lung or there is separate tumor nodule(s) in the same lobe as the primary." .

obo:OBI_0002242 a obo:OBI_0002232 ;
  rdfs:label "pT4 (lung)" ;
  rdfs:comment "A pathologic primary tumor stage for lung according to AJCC 7th edition indicating that the tumor of any size that invades any of the following: mediastinum, heart, great vessels, trachea, recurrent laryngeal nerve, esophagus, vertebral body, carina or there is separate tumor nodule(s) in a different ipsilateral lobe to that of the primary." .
