PREFIX obo:
PREFIX rdf:
PREFIX rdfs:
PREFIX xsd:
obo:SO_0000336 a rdfs:Class ;
rdfs:label "pseudogene" ;
rdfs:comment "A sequence that closely resembles a known functional gene, at another locus within a genome, that is non-functional as a consequence of (usually several) mutations that prevent either its transcription or translation (or both). In general, pseudogenes result from either reverse transcription of a transcript of their \"normal\" paralog (SO:0000043) (in which case the pseudogene typically lacks introns and includes a poly(A) tail) or from recombination (SO:0000044) (in which case the pseudogene is typically a tandem duplication of its \"normal\" paralog)." ;
rdfs:subClassOf obo:SO_0001411 .
a rdfs:Class ;
rdfs:label "RNA sequence" ;
rdfs:comment "An RNA sequence." ;
rdfs:subClassOf .
obo:DOID_0060037 a rdfs:Class ;
rdfs:label "developmental disorder of mental health"@en ;
rdfs:comment "A disease of mental health that occur during a child's developmental period between birth and age 18 resulting in retarding of the child's psychological or physical development."@en ;
rdfs:subClassOf obo:DOID_150 .
obo:OBI_0000916 a rdfs:Class ;
rdfs:label "flow cytometry assay" ;
rdfs:comment "A cytometry assay in which an input cell population is put in solution, is passed by a laser, and optical sensors are used to detect scattering of the laser light and/or fluorescence of specific markers to count and characterize the particles in solution."@en ;
rdfs:subClassOf obo:OBI_0001977 .
obo:GO_0005488 a rdfs:Class ;
rdfs:label "binding" ;
rdfs:comment "The selective, non-covalent, often stoichiometric, interaction of a molecule with one or more specific sites on another molecule." ;
rdfs:subClassOf obo:GO_0003674 .
obo:GO_0036094 a rdfs:Class ;
rdfs:label "small molecule binding" ;
rdfs:comment "Binding to a small molecule, any low molecular weight, monomeric, non-encoded molecule." ;
rdfs:subClassOf obo:GO_0005488 .
obo:NCIT_C70699 a rdfs:Class ;
rdfs:label "Biospecimen" ;
rdfs:comment "Any material sample taken from a biological entity for testing, diagnostic, propagation, treatment or research purposes, including a sample obtained from a living organism or taken from the biological object after halting of all its life functions. Biospecimen can contain one or more components including but not limited to cellular molecules, cells, tissues, organs, body fluids, embryos, and body excretory products." ;
rdfs:subClassOf obo:OBI_0100051 .
obo:BFO_0000017 a rdfs:Class ;
rdfs:label "realizable entity"@en ;
rdfs:comment "A specifically dependent continuant that inheres in continuant entities and are not exhibited in full at every time in which it inheres in an entity or group of entities. The exhibition or actualization of a realizable entity is a particular manifestation, functioning or process that occurs under certain circumstances."@en ;
rdfs:subClassOf obo:BFO_0000020 .
obo:UBERON_0000465 a rdfs:Class ;
rdfs:label "material anatomical entity" ;
rdfs:comment "Anatomical entity that has mass." ;
rdfs:subClassOf obo:UBERON_0001062 .
a rdfs:Class ;
rdfs:label "nurse"@en ;
rdfs:subClassOf .
a rdfs:Class ;
rdfs:label "Imaging" ;
rdfs:comment "The visual representation of an object." ;
rdfs:subClassOf .
obo:GO_0110165 a rdfs:Class ;
rdfs:label "cellular anatomical structure" ;
rdfs:comment "A part of a cellular organism consisting of a material entity with granularity above the level of a protein complex but below that of an anatomical system. Note that cellular organisms exclude viruses." ;
rdfs:subClassOf obo:GO_0005575 .
obo:ENVO_01000840 a rdfs:Class ;
rdfs:label "thermolysis"@en ;
rdfs:comment "A chemical decomposition (the separation of a single chemical compound into its two or more elemental parts or to simpler compounds) caused by heat." ;
rdfs:subClassOf obo:ENVO_03000043 .
obo:OMIT_0014521 a rdfs:Class ;
rdfs:label "Teaching Materials" ;
rdfs:subClassOf obo:IAO_0000030 .
obo:OBI_0000094 a rdfs:Class ;
rdfs:label "material processing" ;
rdfs:comment "A planned process which results in physical changes in a specified input material." ;
rdfs:subClassOf obo:OBI_0000011 .
obo:BFO_0000034 a rdfs:Class ;
rdfs:label "function"@en ;
rdfs:subClassOf obo:BFO_0000016 .
obo:STATO_0000254 a rdfs:Class ;
rdfs:label "allele frequency" ;
rdfs:comment "The allele frequency is a data item which denotes the incidence of a gene variant in a population. It is calculated as a ratio, by dividing the number of copies of a particular allele by the number of copies of all alleles at the genetic place (locus) in a population."@en ;
rdfs:subClassOf obo:STATO_0000184 .
obo:OBI_0001065 a rdfs:Class ;
rdfs:label "stereo microscope" ;
rdfs:comment "An optical microscope that uses two separate optical paths with two objectives and two eyepieces to provide slightly different viewing angles to the left and right eyes."@en ;
rdfs:subClassOf obo:OBI_0000940 .
a rdfs:Class ;
rdfs:label "treatment" ;
rdfs:comment "A planned process intended to modify or alter a condition or characteristic of an organism or individual." ;
rdfs:subClassOf obo:OBI_0000011 .
a rdfs:Class ;
rdfs:label "genetic disorder" ;
rdfs:comment "A disease that is caused by genetic modifications where those modifications are inherited from a parent's genome." ;
rdfs:subClassOf obo:OGMS_0000031 .
obo:OBI_0600002 a rdfs:Class ;
rdfs:label "tumor grading" ;
rdfs:comment "An assay that determines the grade (severity/stage) of a tumor sample, used in cancer biology to describe abnormalities/qualities of tumor cells or tissues. Values can be described by terms from NCI Thesaurus."@en ;
rdfs:subClassOf obo:OBI_0000070 .
obo:GO_0005515 a rdfs:Class ;
rdfs:label "protein binding" ;
rdfs:comment "Binding to a protein." ;
rdfs:subClassOf obo:GO_0005488 .
a rdfs:Class ;
rdfs:label "injury" ;
rdfs:comment "Damage inflicted on the body as the direct or indirect result of an external force, with or without disruption of structural continuity." ;
rdfs:subClassOf obo:BFO_0000016 .
obo:GO_0070727 a rdfs:Class ;
rdfs:label "cellular macromolecule localization" ;
rdfs:comment "Any process in which a macromolecule is transported to, and/or maintained in, a specific location at the level of a cell. Localization at the cellular level encompasses movement within the cell, from within the cell to the cell surface, or from one location to another at the surface of a cell." ;
rdfs:subClassOf obo:GO_0051641 .
obo:GO_0006338 a rdfs:Class ;
rdfs:label "chromatin remodeling" ;
rdfs:comment "A dynamic process of chromatin reorganization resulting in changes to chromatin structure. These changes allow DNA metabolic processes such as transcriptional regulation, DNA recombination, DNA repair, and DNA replication." ;
rdfs:subClassOf obo:GO_0016043 .
obo:GO_0098802 a rdfs:Class ;
rdfs:label "plasma membrane signaling receptor complex" ;
rdfs:comment "Any protein complex that is part of the plasma membrane and which functions as a signaling receptor." ;
rdfs:subClassOf obo:GO_0032991 .
obo:SO_0000704 a rdfs:Class ;
rdfs:label "gene" ;
rdfs:comment "A region (or regions) that includes all of the sequence elements necessary to encode a functional transcript. A gene may include regulatory regions, transcribed regions and/or other functional sequence regions." ;
rdfs:subClassOf obo:SO_0001411 .
obo:CHEBI_72695 a rdfs:Class ;
rdfs:label "organic molecule" ;
rdfs:comment "Any molecule that consists of at least one carbon atom as part of the electrically neutral entity." ;
rdfs:subClassOf obo:CHEBI_25367 , obo:CHEBI_50860 .
obo:UBERON_0001474 a rdfs:Class ;
rdfs:label "bone element" ;
rdfs:comment "Also called osseous tissue, (Latin: os). Is a type of hard endoskeletal connective tissue found in many vertebrate animals. Bone is the main tissue of body organs that support body structures, protect internal organs, (in conjunction with muscles) facilitate movement; and are involved with cell formation, calcium metabolism, and mineral storage.[AAO]" ;
rdfs:subClassOf obo:UBERON_0000062 .
a rdfs:Class ;
rdfs:label "Map" ;
rdfs:comment "A map of (typically one) DNA sequence annotated with positional or non-positional features." ;
rdfs:subClassOf obo:IAO_0000027 .
a rdfs:Class ;
rdfs:label "Concentration" ;
rdfs:comment "The concentration of a chemical compound." ;
rdfs:subClassOf .
obo:GO_0043170 a rdfs:Class ;
rdfs:label "macromolecule metabolic process" ;
rdfs:comment "The chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass." ;
rdfs:subClassOf obo:GO_0008152 .
a rdfs:Class ;
rdfs:label "genotype" ;
rdfs:comment "The total sum of the genetic information of an organism that is known and relevant to the experiment being performed, including chromosomal, plasmid, viral or other genetic material which has been introduced into the organism either prior to or during the experiment." ;
rdfs:subClassOf .
a rdfs:Class ;
rdfs:label "Protein interactions" ;
rdfs:comment "Protein-protein, protein-DNA/RNA and protein-ligand interactions, including analysis of known interactions and prediction of putative interactions." ;
rdfs:subClassOf obo:MI_0000 .
obo:OBI_0000832 a rdfs:Class ;
rdfs:label "measurement device" ;
rdfs:comment "A device in which a measure function inheres."@en ;
rdfs:subClassOf obo:OBI_0000968 .
obo:SO_0000371 a rdfs:Class ;
rdfs:label "conjugative_transposon" ;
rdfs:comment "A transposon that encodes function required for conjugation." ;
rdfs:subClassOf obo:SO_0000182 .
obo:CL_0011115 a rdfs:Class ;
rdfs:label "precursor cell" ;
rdfs:comment "A cell that, by division or terminal differentiation, can give rise to other cell types." ;
rdfs:subClassOf obo:CL_0000000 .
obo:IAO_0000313 a rdfs:Class ;
rdfs:label "patent"@en ;
rdfs:comment "A document that has been accepted by a patent authority"@en ;
rdfs:subClassOf obo:IAO_0000310 .
a rdfs:Class ;
rdfs:label "Gene report" ;
rdfs:comment "A report on predicted or actual gene structure, regions which make an RNA product and features such as promoters, coding regions, splice sites etc." ;
rdfs:subClassOf obo:IAO_0000088 .
obo:SO_0000772 a rdfs:Class ;
rdfs:label "genomic_island" ;
rdfs:comment "A genomic island is an integrated mobile genetic element, characterized by size (over 10 Kb). It that has features that suggest a foreign origin. These can include nucleotide distribution (oligonucleotides signature, CG content etc.) that differs from the bulk of the chromosome and/or genes suggesting DNA mobility." ;
rdfs:subClassOf obo:SO_0001039 .
obo:MI_0208 a rdfs:Class ;
rdfs:label "genetic interaction (sensu unexpected)" ;
rdfs:comment """An effect in which two genetic perturbations, when combined, result in a phenotype that does not appear to be merely explained by the superimposition or addition of effects of the original perturbations.
ab (not=) E""" ;
rdfs:subClassOf obo:MI_0000 .
obo:SO_0002096 a rdfs:Class ;
rdfs:label "short_tandem_repeat_variation" ;
rdfs:comment "A variation that expands or contracts a tandem repeat with regard to a reference." ;
rdfs:subClassOf obo:SO_0001059 .
a rdfs:Class ;
rdfs:label "Protein name" ;
rdfs:comment "Name of a protein." ;
rdfs:subClassOf , .
obo:CHEBI_50047 a rdfs:Class ;
rdfs:label "organic amino compound" ;
rdfs:comment "A compound formally derived from ammonia by replacing one, two or three hydrogen atoms by organyl groups." ;
rdfs:subClassOf obo:CHEBI_35352 .
obo:SO_0005855 a rdfs:Class ;
rdfs:label "gene_group" ;
rdfs:comment "A collection of related genes." ;
rdfs:subClassOf obo:SO_0001411 .
obo:GO_0007606 a rdfs:Class ;
rdfs:label "sensory perception of chemical stimulus" ;
rdfs:comment "The series of events required for an organism to receive a sensory chemical stimulus, convert it to a molecular signal, and recognize and characterize the signal. This is a neurological process." ;
rdfs:subClassOf obo:GO_0050877 .
obo:SO_0000400 a rdfs:Class ;
rdfs:label "sequence_attribute" ;
rdfs:comment "An attribute describes a quality of sequence." ;
rdfs:subClassOf obo:BFO_0000019 .
obo:NCIT_C15311 a rdfs:Class ;
rdfs:label "Quality Control" ;
rdfs:comment "Set of measurements and inspections taken to verify that performance of equipment and procedures remains within specified limits." ;
rdfs:subClassOf obo:OBI_0000011 .
a rdfs:Class ;
rdfs:label "Gene functional annotation" ;
rdfs:comment "Annotate one or more sequences with functional information, such as cellular processes or metaobolic pathways, by reference to a controlled vocabulary - invariably the Gene Ontology (GO)." ;
rdfs:subClassOf .
obo:FBbi_00000364 a rdfs:Class ;
rdfs:label "light-sheet illumination" ;
rdfs:comment "illumination in the form of a thin sheet of light directed perpendicular to the optic axis" ;
rdfs:subClassOf obo:CHMO_0000067 .
obo:CHMO_0000068 a rdfs:Class ;
rdfs:label "electron microscopy" ;
rdfs:comment "Microscopy where the specimen is bombarded with a finely focused (<10 nm diameter) electron beam with an acceleration voltage 50-150 kV under vacuum. The interaction of the electrons with the specimen produces transmitted, secondary, backscattered and diffracted electrons and characteristic X-rays which are detected." ;
rdfs:subClassOf obo:CHMO_0000067 .
obo:OBI_0000716 a rdfs:Class ;
rdfs:label "ChIP-seq assay" ;
rdfs:comment "An assay in which chromatin is immunoprecipitated and subsequently analyzed using a DNA sequencing step to identify which parts of DNA are part of the isolated chromatin"@en ;
rdfs:subClassOf obo:OBI_0001954 .
obo:GO_0005694 a rdfs:Class ;
rdfs:label "chromosome" ;
rdfs:comment "A structure composed of a very long molecule of DNA and associated proteins (e.g. histones) that carries hereditary information." ;
rdfs:subClassOf obo:GO_0043232 .
obo:GO_0070062 a rdfs:Class ;
rdfs:label "extracellular exosome" ;
rdfs:comment "A vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane. Extracellular exosomes, also simply called exosomes, have a diameter of about 40-100 nm." ;
rdfs:subClassOf obo:GO_1903561 .
obo:UBERON_0000948 a rdfs:Class ;
rdfs:label "heart" ;
rdfs:comment "Blood pumping organ composed of four chambers: sinus venosus, atrium, cardiac ventricle and bulbus arteriosus.[TAO]" ;
rdfs:subClassOf obo:UBERON_0005177 .
obo:PR_000037070 a rdfs:Class ;
rdfs:label "phosphoprotein" ;
rdfs:comment "A protein that includes at least one phosphorylated residue." ;
rdfs:subClassOf obo:PR_000000001 .
obo:NCIT_C18143 a rdfs:Class ;
rdfs:label "Gene Knockout" ;
rdfs:comment "Refers to the targeted disruption of a gene within its normal biological context. Utilized to examine the involvement of a gene in a complex biological process." ;
rdfs:subClassOf obo:OBI_0000094 .
obo:ENVO_00002034 a rdfs:Class ;
rdfs:label "biofilm" ;
rdfs:comment "A complex aggregation of microorganisms marked by the excretion of a protective and adhesive matrix; usually adhering to a substratum." ;
rdfs:subClassOf obo:ENVO_01000549 .
obo:GO_0032502 a rdfs:Class ;
rdfs:label "developmental process" ;
rdfs:comment "A biological process whose specific outcome is the progression of an integrated living unit: an anatomical structure (which may be a subcellular structure, cell, tissue, or organ), or organism over time from an initial condition to a later condition." ;
rdfs:subClassOf obo:GO_0008150 .
obo:OBI_0001173 a rdfs:Class ;
rdfs:label "service" ;
rdfs:comment "A planned process in which a service provider performs a task (i.e. a planned process) for a service consumer."@en ;
rdfs:subClassOf obo:OBI_0000011 .
obo:GO_0009536 a rdfs:Class ;
rdfs:label "plastid" ;
rdfs:comment "Any member of a family of organelles found in the cytoplasm of plants and some protists, which are membrane-bounded and contain DNA. Plant plastids develop from a common type, the proplastid." ;
rdfs:subClassOf obo:GO_0043231 .
a rdfs:Class ;
rdfs:label "Codon usage table" ;
rdfs:comment "Table of codon usage data calculated from one or more nucleic acid sequences." ;
rdfs:subClassOf obo:IAO_0000027 .
obo:BFO_0000030 a rdfs:Class ;
rdfs:label "object"@en ;
rdfs:subClassOf obo:BFO_0000040 .
obo:GO_0000398 a rdfs:Class ;
rdfs:label "mRNA splicing, via spliceosome" ;
rdfs:comment "The joining together of exons from one or more primary transcripts of messenger RNA (mRNA) and the excision of intron sequences, via a spliceosomal mechanism, so that mRNA consisting only of the joined exons is produced." ;
rdfs:subClassOf obo:GO_0006397 , obo:GO_0008380 .
obo:CL_0000842 a rdfs:Class ;
rdfs:label "mononuclear leukocyte" ;
rdfs:comment "A leukocyte with a single non-segmented nucleus in the mature form." ;
rdfs:subClassOf obo:CL_0000226 , obo:CL_0000738 .
a rdfs:Class ;
rdfs:label "Genotyping" ;
rdfs:comment "Analyse DNA sequence data to identify differences between the genetic composition (genotype) of an individual compared to other individual's or a reference sequence." ;
rdfs:subClassOf .
obo:NCIT_C17004 a rdfs:Class ;
rdfs:label "Genetic Polymorphism" ;
rdfs:comment "The regular and simultaneous occurrence of alternative nucleotide sequences at equivalent locations of the genetic material among individuals of a single interbreeding population that are not maintained by recurrent mutation. Polymorphisms may range in size from single nucleotide to large nucleotide sequence variation visible at the chromosomal level." ;
rdfs:subClassOf obo:SO_0001059 .
a rdfs:Class ;
rdfs:label "Protein function prediction" ;
rdfs:comment "Predict the biological or biochemical role of a protein, or other aspects of a protein function." ;
rdfs:subClassOf , .
obo:IAO_0000183 a rdfs:Class ;
rdfs:label "dendrogram"@en ;
rdfs:comment """A dendrogram is a report graph which is a tree diagram
frequently used to illustrate the arrangement of the clusters produced by a
clustering algorithm."""@en ;
rdfs:subClassOf obo:IAO_0000038 .
a rdfs:Class ;
rdfs:label "strain" ;
rdfs:comment "A population of organisms that is geneticaly different from others of the same species and possessing a set of defined characteristics." ;
rdfs:subClassOf obo:OBI_0000181 .
obo:OBI_0500000 a rdfs:Class ;
rdfs:label "study design"@en ;
rdfs:comment "A plan specification comprised of protocols (which may specify how and what kinds of data will be gathered) that are executed as part of an investigation and is realized during a study design execution."@en ;
rdfs:subClassOf obo:IAO_0000104 .
obo:PATO_0002070 a rdfs:Class ;
rdfs:label "affinity" ;
rdfs:comment "A molecular quality that arises from the molecular attraction exerted between two atoms or compounds." ;
rdfs:subClassOf obo:PATO_0001241 .
obo:CLO_0037307 a rdfs:Class ;
rdfs:label "induced pluripotent stem cell line cell"@en ;
rdfs:subClassOf obo:CLO_0037224 .
a rdfs:Class ;
rdfs:label "Sample annotation" ;
rdfs:comment "Annotation on a biological sample, for example experimental factors and their values." ;
rdfs:subClassOf .
obo:ENVO_01001654 a rdfs:Class ;
rdfs:label "aerosol formation process"@en ;
rdfs:comment "A material transformation process during which solid or liquid particles form and are suspended in a mass of air, thus creating an aerosol." ;
rdfs:subClassOf obo:ENVO_03000043 .
obo:OGMS_0000123 a rdfs:Class ;
rdfs:label "clinical data item"@en ;
rdfs:comment "A data item that is about a patient and is the specified output of a health care process assay or diagnostic process" ;
rdfs:subClassOf obo:IAO_0000027 .
obo:ENVO_01000549 a rdfs:Class ;
rdfs:label "mass of biological material"@en ;
rdfs:subClassOf obo:ENVO_01001691 .
obo:UBERON_0000000 a rdfs:Class ;
rdfs:label "processual entity" ;
rdfs:comment "An occurrent [span:Occurrent] that exists in time by occurring or happening, has temporal parts and always involves and depends on some entity." ;
rdfs:subClassOf obo:GO_0008150 .
obo:SO_0001060 a rdfs:Class ;
rdfs:label "sequence_variant" ;
rdfs:comment "A sequence_variant is a non exact copy of a sequence_feature or genome exhibiting one or more sequence_alteration." ;
rdfs:subClassOf obo:SO_0000110 .
obo:SO_0000234 a rdfs:Class ;
rdfs:label "mRNA" ;
rdfs:comment "Messenger RNA is the intermediate molecule between DNA and protein. It includes UTR and coding sequences. It does not contain introns." ;
rdfs:subClassOf obo:SO_0000233 .
obo:CL_0002242 a rdfs:Class ;
rdfs:label "nucleate cell" ;
rdfs:comment "A cell containing at least one nucleus." ;
rdfs:subClassOf obo:CL_0000000 .
a rdfs:Class ;
rdfs:label "Laboratory animal science" ;
rdfs:comment "The use of animals and alternatives in experimental research." ;
rdfs:subClassOf obo:OBI_0000011 .
obo:DOID_150 a rdfs:Class ;
rdfs:label "disease of mental health"@en ;
rdfs:comment "A disease that involves a psychological or behavioral pattern generally associated with subjective distress or disability that occurs in an individual, and which are not a part of normal development or culture."@en ;
rdfs:subClassOf obo:OGMS_0000031 .
obo:SO_0000162 a rdfs:Class ;
rdfs:label "splice_site" ;
rdfs:comment "Consensus region of primary transcript bordering junction of splicing. A region that overlaps exactly 2 base and adjacent_to splice_junction." ;
rdfs:subClassOf obo:SO_0000835 .
obo:SO_0001006 a rdfs:Class ;
rdfs:label "prophage" ;
rdfs:comment "A phage genome after it has established in the host genome in a latent/immune state either as a plasmid or as an integrated \"island\"." ;
rdfs:subClassOf obo:SO_0001039 .
obo:ENVO_01000839 a rdfs:Class ;
rdfs:label "combustion process"@en ;
rdfs:comment "Combustion or burning is a high-temperature exothermic redox chemical reaction between a fuel and an oxidant that produces oxidized, often gaseous products, in a mixture termed as smoke." ;
rdfs:subClassOf obo:ENVO_01000840 , obo:ENVO_01001654 .
a rdfs:Class ;
rdfs:label "Quantification" ;
rdfs:comment "Counting and measuring experimentally determined observations into quantities." ;
rdfs:subClassOf .
obo:OBCS_0000220 a rdfs:Class ;
rdfs:label "derived data from inferential statistical analysis"@en ;
rdfs:comment "A data item that is derived from an inferential statistical data analysis." ;
rdfs:subClassOf obo:OBCS_0000218 .
obo:GO_0048869 a rdfs:Class ;
rdfs:label "cellular developmental process" ;
rdfs:comment "A biological process whose specific outcome is the progression of a cell over time from an initial condition to a later condition." ;
rdfs:subClassOf obo:GO_0009987 , obo:GO_0032502 .
a rdfs:Class ;
rdfs:label "Sequence analysis" ;
rdfs:comment "Analyse one or more known molecular sequences." ;
rdfs:subClassOf .
a rdfs:Class ;
rdfs:label "Function analysis" ;
rdfs:comment "The study of gene and protein function including the prediction of functional properties of a protein." ;
rdfs:subClassOf .
obo:GO_0009451 a rdfs:Class ;
rdfs:label "RNA modification" ;
rdfs:comment "The covalent alteration of one or more nucleotides within an RNA molecule to produce an RNA molecule with a sequence that differs from that coded genetically." ;
rdfs:subClassOf obo:GO_0016070 , obo:GO_0043412 .
obo:CHMO_0000141 a rdfs:Class ;
rdfs:label "diffraction method" ;
rdfs:comment "Any detection or measurement method where the structure of a crystal or molecule can be determined by directing a beam of particles or radiation at a sample and recording the resulting diffraction pattern." ;
rdfs:subClassOf obo:CHMO_0000140 .
a rdfs:Class ;
rdfs:label "Molecular property (general)" ;
rdfs:comment "General data for a molecule." ;
rdfs:subClassOf .
obo:OBI_0000047 a rdfs:Class ;
rdfs:label "processed material"@en ;
rdfs:comment "Is a material entity that is created or changed during material processing."@en ;
rdfs:subClassOf obo:BFO_0000040 .
obo:SO_0000859 a rdfs:Class ;
rdfs:label "paralogous" ;
rdfs:comment "An attribute describing a kind of homology where divergence occurred after a duplication event." ;
rdfs:subClassOf obo:SO_0000857 .
obo:OBI_0001528 a rdfs:Class ;
rdfs:label "material service" ;
rdfs:comment "A service which has a material entity as specified input and/or specified output."@en ;
rdfs:subClassOf obo:OBI_0001173 .
obo:CHEBI_33695 a rdfs:Class ;
rdfs:label "information biomacromolecule" ;
rdfs:subClassOf obo:CHEBI_33694 .
obo:ENVO_01001852 a rdfs:Class ;
rdfs:label "energy transfer process"@en ;
rdfs:comment "A process during which one entity loses energy to another entity." ;
rdfs:subClassOf obo:ENVO_02500000 .
obo:MI_0064 a rdfs:Class ;
rdfs:label "interologs mapping" ;
rdfs:comment "Protein interactions, experimentally detected in an organism, are extended to a second organism assuming that homologue proteins, in different organisms, maintain their interaction properties." ;
rdfs:subClassOf .
obo:CHEBI_33595 a rdfs:Class ;
rdfs:label "cyclic compound" ;
rdfs:comment "Any molecule that consists of a series of atoms joined together to form a ring." ;
rdfs:subClassOf obo:CHEBI_25367 .
obo:OGMS_0000073 a rdfs:Class ;
rdfs:label "diagnosis" ;
rdfs:comment "The representation of a conclusion of a diagnostic process."@en ;
rdfs:subClassOf obo:OGMS_0000123 .
obo:GO_0048523 a rdfs:Class ;
rdfs:label "negative regulation of cellular process" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level." ;
rdfs:subClassOf obo:GO_0050794 .
obo:OBI_1000049 a rdfs:Class ;
rdfs:label "whole mount tissue" ;
rdfs:comment "A whole organism preparation resulting from a histological preparation known as whole mount preparation where the whole specimen is mounted or spread on the microscope (glass) slide"@en ;
rdfs:subClassOf obo:OBI_0000680 , obo:OBI_0000953 .
obo:UBERON_0000178 a rdfs:Class ;
rdfs:label "blood" ;
rdfs:comment "Highly specialized circulating tissue consisting of several types of cells suspended in a fluid medium known as plasma.[AAO]" ;
rdfs:subClassOf obo:UBERON_0000465 .
obo:ENVO_01001788 a rdfs:Class ;
rdfs:label "marine ecosystem"@en ;
rdfs:subClassOf obo:ENVO_01000320 , obo:ENVO_01001787 .
a rdfs:Class ;
rdfs:label "Data identity and mapping" ;
rdfs:comment "Topic concerning the identity of biological entities, or reports on such entities, and the mapping of entities and records in different databases." ;
rdfs:subClassOf obo:T4FS_0000141 .
obo:SO_0001039 a rdfs:Class ;
rdfs:label "integrated_mobile_genetic_element" ;
rdfs:comment "An MGE that is integrated into the host chromosome." ;
rdfs:subClassOf obo:SO_0001037 .
obo:PATO_0001018 a rdfs:Class ;
rdfs:label "physical quality" ;
rdfs:comment "A quality of a physical entity that exists through action of continuants at the physical level of organisation in relation to other entities." ;
rdfs:subClassOf obo:PATO_0001241 .
obo:CHEBI_59132 a rdfs:Class ;
rdfs:label "antigen" ;
rdfs:comment "Any substance that stimulates an immune response in the body, such as through antibody production or by presentation to a T-cell receptor after binding to a major histocompability complex (MHC)." ;
rdfs:subClassOf obo:CHEBI_24432 .
obo:NCIT_C16565 a rdfs:Class ;
rdfs:label "Evolution" ;
rdfs:comment "The process by which organism populations change over successive generations that is influenced by gene mutation and natural selection." ;
rdfs:subClassOf obo:UBERON_0000000 .
obo:GO_0007610 a rdfs:Class ;
rdfs:label "behavior" ;
rdfs:comment "The internally coordinated responses (actions or inactions) of animals (individuals or groups) to internal or external stimuli, via a mechanism that involves nervous system activity." ;
rdfs:subClassOf obo:GO_0032501 .
obo:OBI_0100014 a rdfs:Class ;
rdfs:label "chimera"@en ;
rdfs:comment "An organism which contains cells or tissues with a different genotype"@en ;
rdfs:subClassOf obo:OBI_0100026 .
obo:GO_0060255 a rdfs:Class ;
rdfs:label "regulation of macromolecule metabolic process" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass." ;
rdfs:subClassOf obo:GO_0019222 .
obo:OBI_0000398 a rdfs:Class ;
rdfs:label "image creation device" ;
rdfs:comment "An image creation device is a device which captures a digitized image of an object"@en ;
rdfs:subClassOf obo:OBI_0000832 .
obo:OBI_0001876 a rdfs:Class ;
rdfs:label "cell culture" ;
rdfs:comment "A material entity comprised of cultured cells and the media in which they are being propagated or stored."@en ;
rdfs:subClassOf obo:OBI_0000047 .
obo:SO_0000657 a rdfs:Class ;
rdfs:label "repeat_region" ;
rdfs:comment "A region of sequence containing one or more repeat units." ;
rdfs:subClassOf obo:SO_0001411 .
obo:OBI_0600020 a rdfs:Class ;
rdfs:label "histological assay" ;
rdfs:comment "An assay that uses visual examination of cells or tissue (or images of them) to make an assessment regarding a quality of the cells or tissue. This assay can include steps of staining, imaging, and judgement."@en ;
rdfs:subClassOf obo:OBI_0000070 .
obo:OBI_0000968 a rdfs:Class ;
rdfs:label "device" ;
rdfs:comment "A material entity that is designed to perform a function in a scientific investigation, but is not a reagent."@en ;
rdfs:subClassOf obo:OBI_0000047 .
a rdfs:Class ;
rdfs:label "cardiovascular disease" ;
rdfs:comment "A non-neoplastic or neoplastic disorder affecting the heart or the vessels (arteries, veins and lymph vessels). Representative examples of non-neoplastic cardiovascular disorders are endocarditis and hypertension. Representative examples of neoplastic cardiovascular disorders are endocardial myxoma and angiosarcoma." ;
rdfs:subClassOf obo:OGMS_0000031 .
obo:GO_0032501 a rdfs:Class ;
rdfs:label "multicellular organismal process" ;
rdfs:comment "Any biological process, occurring at the level of a multicellular organism, pertinent to its function." ;
rdfs:subClassOf obo:GO_0008150 .
obo:SO_0000101 a rdfs:Class ;
rdfs:label "transposable_element" ;
rdfs:comment "A transposon or insertion sequence. An element that can insert in a variety of DNA sequences." ;
rdfs:subClassOf obo:SO_0001039 .
obo:GO_0050789 a rdfs:Class ;
rdfs:label "regulation of biological process" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule." ;
rdfs:subClassOf obo:GO_0065007 .
obo:OBI_0000940 a rdfs:Class ;
rdfs:label "optical microscope" ;
rdfs:comment "A microscope that produces an image of an object by targeting it with an electro-magnetic beam in the visible frequency range"@en ;
rdfs:subClassOf obo:OBI_0400169 .
obo:GO_0019815 a rdfs:Class ;
rdfs:label "B cell receptor complex" ;
rdfs:comment "An immunoglobulin complex that is present in the plasma membrane of B cells and that in its canonical form is composed of two identical immunoglobulin heavy chains and two identical immunoglobulin light chains and a signaling subunit, a heterodimer of the Ig-alpha and Ig-beta proteins." ;
rdfs:subClassOf obo:GO_0019814 , obo:GO_0098802 .
a rdfs:Class ;
rdfs:label "Michaelis constant" ;
rdfs:comment "Synonym: Michaelis-Menten constant " ;
rdfs:subClassOf .
obo:GO_0007155 a rdfs:Class ;
rdfs:label "cell adhesion" ;
rdfs:comment "The attachment of a cell, either to another cell or to an underlying substrate such as the extracellular matrix, via cell adhesion molecules." ;
rdfs:subClassOf obo:GO_0009987 .
obo:PATO_0001415 a rdfs:Class ;
rdfs:label "morbidity" ;
rdfs:comment "A quality inhering in a population by virtue of the proportion of its members that are ill at a given time." ;
rdfs:subClassOf obo:PATO_0001241 .
obo:OMIT_0019939 a rdfs:Class ;
rdfs:label "Benchmarking" ;
rdfs:subClassOf .
obo:UBERON_0002365 a rdfs:Class ;
rdfs:label "exocrine gland" ;
rdfs:comment "A gland that secretes products (excluding hormones and other chemical messengers) into ducts (duct glands) which lead directly into the external environment[WP]. Typical exocrine glands include sweat glands, salivary glands, mammary glands, stomach, liver, pancreas." ;
rdfs:subClassOf obo:UBERON_0002530 .
obo:SO_0000870 a rdfs:Class ;
rdfs:label "trans_spliced" ;
rdfs:comment "An attribute describing transcript sequence that is created by splicing exons from diferent genes." ;
rdfs:subClassOf obo:SO_0000733 .
obo:SO_0000737 a rdfs:Class ;
rdfs:label "mitochondrial_sequence" ;
rdfs:comment "DNA belonging to the genome of a mitochondria." ;
rdfs:subClassOf obo:SO_0000736 .
obo:OBI_0200187 a rdfs:Class ;
rdfs:label "sequence analysis data transformation"@en ;
rdfs:comment "A sequence analysis data transformation is a data transformation that has objective sequence analysis and has the aim of analysing ordered biological data for sequential patterns."@en ;
rdfs:subClassOf obo:OBI_0200000 .
obo:CHEBI_15986 a rdfs:Class ;
rdfs:label "polynucleotide" ;
rdfs:comment "A nucleobase-containing molecular entity with a polymeric structure comprised of a linear sequence of 13 or more nucleotide residues." ;
rdfs:subClassOf obo:CHEBI_33695 , obo:CHEBI_61120 .
a rdfs:Class ;
rdfs:label "Structure" ;
rdfs:comment "3D coordinate and associated data for a macromolecular tertiary (3D) structure or part of a structure." ;
rdfs:subClassOf obo:PATO_0000141 .
obo:UBERON_0000104 a rdfs:Class ;
rdfs:label "life cycle" ;
rdfs:comment "An entire span of an organism's life. In metazoans, commences with the zygote stage and ends with the death of the organism." ;
rdfs:subClassOf obo:UBERON_0000000 .
obo:STATO_0000039 a rdfs:Class ;
rdfs:label "statistic"@en ;
rdfs:comment "a statistic is a measurement datum to describe a dataset or a variable. It is generated by a calculation on set of observed data."@en ;
rdfs:subClassOf obo:IAO_0000027 .
a rdfs:Class ;
rdfs:label "Biocuration"@en ;
rdfs:comment "Biocuration is the extraction of knowledge from unstructured biological and biomedical data into a standard, structured, computable form." ;
rdfs:subClassOf obo:OBI_0302914 .
a rdfs:Class ;
rdfs:label "data storage" ;
rdfs:comment "The storing of digital information. Often this is done for archiving and retrieval purposes." ;
rdfs:subClassOf obo:BFO_0000015 .
obo:CL_0000219 a rdfs:Class ;
rdfs:label "motile cell" ;
rdfs:comment "A cell that moves by its own activities." ;
rdfs:subClassOf obo:CL_0000000 .
obo:SO_0000603 a rdfs:Class ;
rdfs:label "group_II_intron" ;
rdfs:comment "Group II introns are found in rRNA, tRNA and mRNA of organelles in fungi, plants and protists, and also in mRNA in bacteria. They are large self-splicing ribozymes and have 6 structural domains (usually designated dI to dVI). A subset of group II introns also encode essential splicing proteins in intronic ORFs. The length of these introns can therefore be up to 3kb. Splicing occurs in almost identical fashion to nuclear pre-mRNA splicing with two transesterification steps. The 2' hydroxyl of a bulged adenosine in domain VI attacks the 5' splice site, followed by nucleophilic attack on the 3' splice site by the 3' OH of the upstream exon. Protein machinery is required for splicing in vivo, and long range intron to intron and intron-exon interactions are important for splice site positioning. Group II introns are further sub-classified into groups IIA and IIB which differ in splice site consensus, distance of bulged A from 3' splice site, some tertiary interactions, and intronic ORF phylogeny." ;
rdfs:subClassOf obo:SO_0000188 .
obo:MI_0914 a rdfs:Class ;
rdfs:label "association" ;
rdfs:comment "Interaction between molecules that may participate in formation of one, but possibly more, physical complexes. Often describes a set of molecules that are co-purified in a single pull-down or coimmunoprecipitation but might participate in formation of distinct physical complexes sharing a common bait." ;
rdfs:subClassOf obo:MI_0000 .
obo:OMIT_0026082 a rdfs:Class ;
rdfs:label "Metagenome" ;
rdfs:subClassOf obo:SO_0001260 .
a rdfs:Class ;
rdfs:label "Data retrieval" ;
rdfs:comment "Retrieve an entry (or part of an entry) from a data resource that matches a supplied query. This might include some primary data and annotation. The query is a data identifier or other indexed term. For example, retrieve a sequence record with the specified accession number, or matching supplied keywords." ;
rdfs:subClassOf .
obo:OBI_0001177 a rdfs:Class ;
rdfs:label "RNA sequencing assay" ;
rdfs:comment "An assay that determines the sequence of an RNA molecule."@en ;
rdfs:subClassOf obo:OBI_0600047 .
obo:DOID_302 a rdfs:Class ;
rdfs:label "substance abuse"@en ;
rdfs:comment "A substance-related disorder that involves a maladaptive pattern of substance use leading to significant impairment in functioning."@en ;
rdfs:subClassOf obo:DOID_150 .
obo:PATO_0000052 a rdfs:Class ;
rdfs:label "shape" ;
rdfs:comment "A morphological quality inhering in a bearer by virtue of the bearer's ratios of distances between its features (points, edges, surfaces and also holes etc)." ;
rdfs:subClassOf obo:PATO_0000051 .
obo:FBbi_00000267 a rdfs:Class ;
rdfs:label "animation" ;
rdfs:comment "A form of graphical illustration that changes with time to give a sense of motion or represent dynamic changes in the portrayal." ;
rdfs:subClassOf obo:IAO_0000030 .
a rdfs:Class ;
rdfs:label "Enzyme ID" ;
rdfs:comment "A unique, persistent identifier of an enzyme." ;
rdfs:subClassOf .
a rdfs:Class ;
rdfs:label "Protein secondary structure prediction" ;
rdfs:comment "Predict secondary structure of protein sequences." ;
rdfs:subClassOf .
obo:CHEBI_33251 a rdfs:Class ;
rdfs:label "monoatomic hydrogen" ;
rdfs:subClassOf obo:CHEBI_33238 , obo:CHEBI_33260 .
a rdfs:Class ;
rdfs:label "Molecular property" ;
rdfs:comment "A report on the physical (e.g. structural) or chemical properties of molecules, or parts of a molecule." ;
rdfs:subClassOf obo:IAO_0000027 .
obo:IAO_0000314 a rdfs:Class ;
rdfs:label "document part"@en ;
rdfs:comment "An information content entity that is part of a document."@en ;
rdfs:subClassOf obo:IAO_0000030 .
obo:GO_0010629 a rdfs:Class ;
rdfs:label "negative regulation of gene expression" ;
rdfs:comment "Any process that decreases the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product (protein or RNA)." ;
rdfs:subClassOf obo:GO_0010468 , obo:GO_0010558 .
obo:GO_0006457 a rdfs:Class ;
rdfs:label "protein folding" ;
rdfs:comment "The process of assisting in the covalent and noncovalent assembly of single chain polypeptides or multisubunit complexes into the correct tertiary structure." ;
rdfs:subClassOf obo:GO_0009987 .
obo:FBcv_0003036 a rdfs:Class ;
rdfs:label "interactome" ;
rdfs:comment "A project that characterizes the set of inter-molecular interactions in an organism." ;
rdfs:subClassOf obo:IAO_0000030 .
obo:CL_0000234 a rdfs:Class ;
rdfs:label "phagocyte" ;
rdfs:comment "Any cell capable of ingesting particulate matter via phagocytosis." ;
rdfs:subClassOf obo:CL_0000219 , obo:CL_0000325 .
obo:OBI_0003117 a rdfs:Class ;
rdfs:label "3D molecular structure determination assay" ;
rdfs:comment "An assay that determines the 3-dimensional configuration of a molecular entity or molecular complex."@en ;
rdfs:subClassOf obo:OBI_0600045 .
obo:OBI_0600017 a rdfs:Class ;
rdfs:label "assay detecting a molecular label" ;
rdfs:comment "An assay that detects the presence or a quality of a molecular label which is a proxy for the detection of the molecular target to which the label is attached"@en ;
rdfs:subClassOf obo:OBI_0000070 .
obo:OBI_0000912 a rdfs:Class ;
rdfs:label "X-ray crystallography 3D molecular structure determination assay" ;
rdfs:comment "A 3D molecular structure determination assay in which the diffraction of pattern of X-ray beams in a crystal of purified material entities is used to resolve the 3-dimensional structure of the material entity of interest."@en ;
rdfs:subClassOf obo:OBI_0003117 .
obo:CHEBI_36963 a rdfs:Class ;
rdfs:label "organooxygen compound" ;
rdfs:comment "An organochalcogen compound containing at least one carbon-oxygen bond." ;
rdfs:subClassOf obo:CHEBI_36962 .
obo:ENVO_01000204 a rdfs:Class ;
rdfs:label "tropical" ;
rdfs:comment "A tropical condition is an environmental condition in which an environmental system receives high yearly solar irradiance per unit area and, on Earth, the Sun reaches a subsolar point at least once during the solar year. This results in a hot and moist year-round climate at low elevations, which have a monthly average temperature above 18 degrees Celsius." ;
rdfs:subClassOf obo:ENVO_01000203 .
obo:SO_0000733 a rdfs:Class ;
rdfs:label "feature_attribute" ;
rdfs:comment "An attribute describing a located_sequence_feature." ;
rdfs:subClassOf obo:SO_0000400 .
obo:DOID_1826 a rdfs:Class ;
rdfs:label "epilepsy"@en ;
rdfs:comment "A brain disease that is characterized by the occurrance of at least two unprovoked seizures resulting from a persistent epileptogenic abnormality of the brain that is able to spontaneously generate paroxysmal activity and typically manifested by sudden brief episodes of altered or diminished consciousness, involuntary movements, or convulsions."@en ;
rdfs:subClassOf obo:DOID_331 .
obo:GO_0140352 a rdfs:Class ;
rdfs:label "export from cell" ;
rdfs:comment "The directed movement of some substance from a cell, into the extracellular region. This may occur via transport across the plasma membrane or via exocytosis." ;
rdfs:subClassOf obo:GO_0006810 , obo:GO_0009987 .
obo:OBI_0002692 a rdfs:Class ;
rdfs:label "polymerase chain reaction assay" ;
rdfs:comment "An assay that uses polymerase chain reaction technique to amplify DNA."@en ;
rdfs:subClassOf obo:OBI_0000070 .
obo:OBI_0001199 a rdfs:Class ;
rdfs:label "in vivo design" ;
rdfs:comment "A study design that is conducted entirely in a living organism, e.g. a compound treatment in a mouse model."@en ;
rdfs:subClassOf obo:OBI_0500000 .
a rdfs:Class ;
rdfs:label "medical practitioner"@en ;
rdfs:subClassOf obo:BFO_0000023 .
obo:PATO_0001993 a rdfs:Class ;
rdfs:label "multicellular" ;
rdfs:comment "A cellularity quality inhering in a bearer by virtue of the bearer's consisting of more than one cell." ;
rdfs:subClassOf obo:PATO_0001995 .
obo:CHEBI_33284 a rdfs:Class ;
rdfs:label "nutrient" ;
rdfs:comment "A nutrient is a food component that an organism uses to survive and grow." ;
rdfs:subClassOf obo:CHEBI_52211 .
obo:SO_0000180 a rdfs:Class ;
rdfs:label "retrotransposon" ;
rdfs:comment "A transposable element that is incorporated into a chromosome by a mechanism that requires reverse transcriptase." ;
rdfs:subClassOf obo:SO_0000101 .
obo:SO_0000646 a rdfs:Class ;
rdfs:label "siRNA" ;
rdfs:comment "A small RNA molecule that is the product of a longer exogenous or endogenous dsRNA, which is either a bimolecular duplex or very long hairpin, processed (via the Dicer pathway) such that numerous siRNAs accumulate from both strands of the dsRNA. siRNAs trigger the cleavage of their target molecules." ;
rdfs:subClassOf obo:SO_0000370 .
obo:CHMO_0000999 a rdfs:Class ;
rdfs:label "separation method" ;
rdfs:comment "A method that results in the separation of two or more components according to some property." ;
rdfs:subClassOf obo:OBI_0000094 .
obo:UBERON_0001062 a rdfs:Class ;
rdfs:label "anatomical entity" ;
rdfs:comment "Biological entity that is either an individual member of a biological species or constitutes the structural organization of an individual member of a biological species." ;
rdfs:subClassOf obo:BFO_0000040 .
obo:PATO_0001241 a rdfs:Class ;
rdfs:label "physical object quality" ;
rdfs:comment "A quality which inheres in a continuant." ;
rdfs:subClassOf obo:BFO_0000019 .
obo:GO_0050909 a rdfs:Class ;
rdfs:label "sensory perception of taste" ;
rdfs:comment "The series of events required for an organism to receive a gustatory stimulus, convert it to a molecular signal, and recognize and characterize the signal. Gustation involves the direct detection of chemical composition, usually through contact with chemoreceptor cells. This is a neurological process." ;
rdfs:subClassOf obo:GO_0007606 .
obo:CLO_0037224 a rdfs:Class ;
rdfs:label "stem cell line cell"@en ;
rdfs:subClassOf obo:CLO_0000001 .
obo:OBI_0302840 a rdfs:Class ;
rdfs:label "curated information"@en ;
rdfs:comment "An information content entity that has undergone a digital curation performed by a curator for accuracy checks and compliance with curation requirements. Information which has been assessed for accuracy by domain experts."@en ;
rdfs:subClassOf obo:IAO_0000030 .
obo:MI_0093 a rdfs:Class ;
rdfs:label "protein sequence identification" ;
rdfs:comment "Single amino acid identification along a protein sequence." ;
rdfs:subClassOf .
obo:CHEBI_33712 a rdfs:Class ;
rdfs:label "N-terminal amino-acid residue" ;
rdfs:comment "The residue in a peptide that has an amino group that is free, or at least not acylated by another amino-acid residue, is called N-terminal." ;
rdfs:subClassOf obo:CHEBI_33708 .
a rdfs:Class ;
rdfs:label "karyotype" ;
rdfs:comment "A karyotype is the number and appearance of chromosomes in the nucleus of a eukaryotic cell." ;
rdfs:subClassOf obo:BFO_0000019 .
a rdfs:Class ;
rdfs:label "Mass spectrum" ;
rdfs:comment "Spectra from mass spectrometry." ;
rdfs:subClassOf obo:CHMO_0000800 .
obo:NCIT_C15239 a rdfs:Class ;
rdfs:label "Patient Care" ;
rdfs:comment "Any of the services rendered for the benefit of a patient." ;
rdfs:subClassOf obo:OAE_0000094 .
obo:GO_2000628 a rdfs:Class ;
rdfs:label "regulation of miRNA metabolic process" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of miRNA metabolic process." ;
rdfs:subClassOf obo:GO_0051252 .
a rdfs:Class ;
rdfs:label "Transcription factor binding site prediction" ;
rdfs:comment "Identify or predict transcription factor binding sites in DNA sequences." ;
rdfs:subClassOf .
obo:MI_0964 a rdfs:Class ;
rdfs:label "infrared spectroscopy" ;
rdfs:comment "Subset of spectroscopy that deals with the infrared region of the electromagnetic spectrum." ;
rdfs:subClassOf obo:OBI_0000070 .
obo:CHEBI_33238 a rdfs:Class ;
rdfs:label "monoatomic entity" ;
rdfs:comment "A monoatomic entity is a molecular entity consisting of a single atom." ;
rdfs:subClassOf obo:CHEBI_33259 .
obo:UBERON_0000955 a rdfs:Class ;
rdfs:label "brain" ;
rdfs:comment "Part of the central nervous system situated within the cranium and composed of both nerve cell bodies and nerve fibers.[AAO]" ;
rdfs:subClassOf obo:UBERON_0000062 , obo:UBERON_0004121 .
a rdfs:Class ;
rdfs:label "deletion" ;
rdfs:subClassOf .
obo:CL_0000738 a rdfs:Class ;
rdfs:label "leukocyte" ;
rdfs:comment "An achromatic cell of the myeloid or lymphoid lineages capable of ameboid movement, found in blood or other tissue." ;
rdfs:subClassOf obo:CL_0000219 , obo:CL_0000255 , obo:CL_0000988 , obo:CL_0002242 .
obo:OBI_1110021 a rdfs:Class ;
rdfs:label "infection process"@en ;
rdfs:comment "the detrimental process in which an infectious agent colonizes or replicates in a host environment"@en ;
rdfs:subClassOf obo:OBI_1110122 .
obo:OBI_0001905 a rdfs:Class ;
rdfs:label "secondary cultured cell population" ;
rdfs:subClassOf obo:OBI_0100060 .
obo:CL_0000010 a rdfs:Class ;
rdfs:label "cultured cell" ;
rdfs:subClassOf obo:CL_0000578 .
a rdfs:Class ;
rdfs:label "RNA secondary structure" ;
rdfs:comment "An informative report of secondary structure (predicted or real) of an RNA molecule." ;
rdfs:subClassOf .
obo:IAO_0000308 a rdfs:Class ;
rdfs:label "figure"@en ;
rdfs:comment "An information content entity consisting of a two dimensional arrangement of information content entities such that the arrangement itself is about something."@en ;
rdfs:subClassOf obo:IAO_0000030 .
a rdfs:Class ;
rdfs:label "gene-disease association"@en ;
rdfs:subClassOf obo:MI_0914 .
obo:SO_0000740 a rdfs:Class ;
rdfs:label "plastid_sequence" ;
rdfs:comment "DNA belonging to the genome of a plastid such as a chloroplast." ;
rdfs:subClassOf obo:SO_0000736 .
obo:GO_0006805 a rdfs:Class ;
rdfs:label "xenobiotic metabolic process" ;
rdfs:comment "The chemical reactions and pathways involving a xenobiotic compound, a compound foreign to the organism exposed to it. It may be synthesized by another organism (like ampicilin) or it can be a synthetic chemical." ;
rdfs:subClassOf obo:GO_0008152 .
obo:CL_0000518 a rdfs:Class ;
rdfs:label "phagocyte (sensu Vertebrata)" ;
rdfs:comment "A phagocyte in vertebrates that is able to phagocytosis." ;
rdfs:subClassOf obo:CL_0000234 , obo:CL_0000255 .
obo:SO_1000032 a rdfs:Class ;
rdfs:label "delins" ;
rdfs:comment "A sequence alteration which included an insertion and a deletion, affecting 2 or more bases." ;
rdfs:subClassOf obo:SO_0001059 .
obo:FBcv_0003039 a rdfs:Class ;
rdfs:label "chemical screen" ;
rdfs:comment "A project that searches for chemicals, natural or synthetic, that elicit some biological effect." ;
rdfs:subClassOf .
obo:CHEBI_50860 a rdfs:Class ;
rdfs:label "organic molecular entity" ;
rdfs:comment "Any molecular entity that contains carbon." ;
rdfs:subClassOf obo:CHEBI_33675 .
obo:OAE_0000235 a rdfs:Class ;
rdfs:label "radiotherapy"@en ;
rdfs:comment "a therapeutic intervention that uses radiation" ;
rdfs:subClassOf obo:OAE_0000094 .
obo:MI_1100 a rdfs:Class ;
rdfs:label "bioactive entity" ;
rdfs:comment "Molecules showing activity in a living system but not encoded by a genomic sequence." ;
rdfs:subClassOf obo:MI_0000 .
obo:GO_0007135 a rdfs:Class ;
rdfs:label "meiosis II" ;
rdfs:comment "The second nuclear division of meiosis, in which the two chromatids in each chromosome are separated, resulting in four daughter nuclei from the two nuclei produced in meiosis II." ;
rdfs:subClassOf obo:GO_0140013 .
a rdfs:Class ;
rdfs:label "Linkage disequilibrium calculation" ;
rdfs:comment "Calculate linkage disequilibrium; the non-random association of alleles or polymorphisms at two or more loci (not necessarily on the same chromosome)." ;
rdfs:subClassOf .
obo:CHEBI_26079 a rdfs:Class ;
rdfs:label "phosphoric acid derivative" ;
rdfs:subClassOf obo:CHEBI_36359 .
obo:GO_0043229 a rdfs:Class ;
rdfs:label "intracellular organelle" ;
rdfs:comment "Organized structure of distinctive morphology and function, occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton. Excludes the plasma membrane." ;
rdfs:subClassOf obo:GO_0043226 .
obo:ENVO_01000320 a rdfs:Class ;
rdfs:label "marine environment" ;
rdfs:comment "An enviroment system which is determined by an ocean or sea." ;
rdfs:subClassOf obo:ENVO_01000254 .
obo:SO_0005851 a rdfs:Class ;
rdfs:label "gene_array" ;
rdfs:comment "An array includes two or more genes, or two or more gene subarrays, contiguously arranged where the individual genes, or subarrays, are either identical in sequence, or essentially so." ;
rdfs:subClassOf obo:SO_0005855 .
a rdfs:Class ;
rdfs:label "Protein identifier" ;
rdfs:comment "Identifier of a protein." ;
rdfs:subClassOf .
obo:CHEBI_50803 a rdfs:Class ;
rdfs:label "nanoparticle" ;
rdfs:comment "A nanosized spherical or capsule-shaped structure." ;
rdfs:subClassOf obo:CHEBI_36357 .
obo:MI_0328 a rdfs:Class ;
rdfs:label "small molecule" ;
rdfs:comment "Molecule not part of or directly encoded by the genome, encompasses any constitutionally or isotopically distinct atom, molecule, ion, ion pair, radical, radical ion, complex, conformer, etc., identifiable as a separately distinguishable entity." ;
rdfs:subClassOf obo:CHEBI_23367 .
obo:SO_0001067 a rdfs:Class ;
rdfs:label "polypeptide_motif" ;
rdfs:comment "A sequence motif is a short (up to 20 amino acids) region of biological interest. Such motifs, although they are too short to constitute functional domains, share sequence similarities and are conserved in different proteins. They display a common function (protein-binding, subcellular location etc.)." ;
rdfs:subClassOf obo:SO_0000839 .
obo:CHEBI_36359 a rdfs:Class ;
rdfs:label "phosphorus oxoacid derivative" ;
rdfs:subClassOf obo:CHEBI_26082 , obo:CHEBI_36357 .
obo:GO_0010467 a rdfs:Class ;
rdfs:label "gene expression" ;
rdfs:comment "The process in which a gene's sequence is converted into a mature gene product (protein or RNA). This includes the production of an RNA transcript and its processing, as well as translation and maturation for protein-coding genes." ;
rdfs:subClassOf obo:GO_0009059 .
obo:CHMO_0000228 a rdfs:Class ;
rdfs:label "spectroscopy" ;
rdfs:comment "The study of the interaction of a sample with radiation or particles for measurement or detection." ;
rdfs:subClassOf obo:OBI_0000070 .
obo:BFO_0000040 a rdfs:Class ;
rdfs:label "material entity" ;
rdfs:comment "An independent continuant that is spatially extended whose identity is independent of that of other entities and can be maintained through time."@en ;
rdfs:subClassOf obo:BFO_0000004 .
obo:CL_0002248 a rdfs:Class ;
rdfs:label "pluripotent stem cell" ;
rdfs:comment "A pluripotent stem cell has the ability to form cells from all three germ layers (ectoderm, mesoderm, and endoderm). However, unlike totipotent stem cells, they cell can not generate all the cells of the whole organism such as placenta." ;
rdfs:subClassOf obo:CL_0000723 .
obo:GO_0006413 a rdfs:Class ;
rdfs:label "translational initiation" ;
rdfs:comment "The process preceding formation of the peptide bond between the first two amino acids of a protein. This includes the formation of a complex of the ribosome, mRNA or circRNA, and an initiation complex that contains the first aminoacyl-tRNA." ;
rdfs:subClassOf obo:GO_0008152 .
obo:CHEBI_24532 a rdfs:Class ;
rdfs:label "organic heterocyclic compound" ;
rdfs:comment "A cyclic compound having as ring members atoms of carbon and at least of one other element." ;
rdfs:subClassOf obo:CHEBI_33285 , obo:CHEBI_33832 .
a rdfs:Class ;
rdfs:label "Evidence" ;
rdfs:comment "Typically a human-readable summary of body of facts or information indicating why a statement is true or valid. This may include a computational prediction, laboratory experiment, literature reference etc." ;
rdfs:subClassOf obo:IAO_0000030 .
obo:OBI_0001848 a rdfs:Class ;
rdfs:label "chromatin interaction analysis by paired-end tag sequencing assay" ;
rdfs:comment "An assay that incorporates chromatin immunoprecipitation (ChIP)-based enrichment, chromatin proximity ligation, Paired-End Tags, and high-throughput sequencing to determine de novo long-range chromatin interactions genome-wide."@en ;
rdfs:subClassOf obo:OBI_0002438 , obo:OBI_0600047 .
a rdfs:Class ;
rdfs:label "unspecified cell type" ;
rdfs:subClassOf obo:CL_0000000 .
obo:SO_0000149 a rdfs:Class ;
rdfs:label "contig" ;
rdfs:comment "A contiguous sequence derived from sequence assembly. Has no gaps, but may contain N's from unavailable bases." ;
rdfs:subClassOf obo:SO_0000143 .
a rdfs:Class ;
rdfs:label "Cropping systems" ;
rdfs:comment "The pattern of crops grown on a given piece of land, or order in which the crops are cultivated over a fixed period." ;
rdfs:subClassOf obo:OBI_0000011 .
obo:GO_0008152 a rdfs:Class ;
rdfs:label "metabolic process" ;
rdfs:comment "A cellular process consisting of the biochemical pathways by which a living organism transforms chemical substances. This includes including anabolism (biosynthetic process) and catabolism (catabolic process). Metabolic processes includes the transformation of small molecules, as well macromolecular processes such as DNA repair and replication, protein synthesis and degradation." ;
rdfs:subClassOf obo:GO_0009987 .
obo:OBCS_0000218 a rdfs:Class ;
rdfs:label "derived data from statistical analysis"@en ;
rdfs:comment "A data item that is derived from a statistical data analysis." ;
rdfs:subClassOf obo:OBCS_0000233 .
obo:NCIT_C41332 a rdfs:Class ;
rdfs:label "Adverse Reaction" ;
rdfs:comment "Any noxious and unintended response(s) to a medical product or procedure, for which a causal relationship with this product or procedure is at least a reasonable possibility i.e., the relationship cannot be ruled out." ;
rdfs:subClassOf obo:GO_0008150 .
obo:ENVO_00000428 a rdfs:Class ;
rdfs:label "biome" ;
rdfs:comment "A biome is an ecosystem which is undergoing climactic ecological succession."@en ;
rdfs:subClassOf obo:ENVO_01000813 , obo:ENVO_01001110 .
obo:OMIT_0025752 a rdfs:Class ;
rdfs:label "Receptors, KIR" ;
rdfs:subClassOf obo:PR_000000001 .
obo:GO_0050877 a rdfs:Class ;
rdfs:label "nervous system process" ;
rdfs:comment "An organ system process carried out by any of the organs or tissues of the neurological system." ;
rdfs:subClassOf obo:GO_0032501 .
a rdfs:Class ;
rdfs:label "Genome assembly" ;
rdfs:comment "The process of assembling many short DNA sequences together such that they represent the original chromosomes from which the DNA originated." ;
rdfs:subClassOf .
obo:UBERON_0010000 a rdfs:Class ;
rdfs:label "multicellular anatomical structure" ;
rdfs:comment "An anatomical structure that has more than one cell as a part." ;
rdfs:subClassOf obo:UBERON_0000061 .
obo:UBERON_0001033 a rdfs:Class ;
rdfs:label "gustatory system" ;
rdfs:comment "The sensory system for the sense of taste." ;
rdfs:subClassOf obo:UBERON_0000061 .
obo:OBI_0000070 a rdfs:Class ;
rdfs:label "assay" ;
rdfs:comment "A planned process with the objective to produce information about the material entity that is the evaluant, by physically examining it or its proxies." ;
rdfs:subClassOf obo:OBI_0000011 .
obo:MI_2025 a rdfs:Class ;
rdfs:label "molecular weight" ;
rdfs:comment "Molecular weight in g/mol, determined from molecular formula or sequence." ;
rdfs:subClassOf .
a rdfs:Class ;
rdfs:label "chemical-gene association"@en ;
rdfs:subClassOf obo:MI_0914 .
obo:MI_0118 a rdfs:Class ;
rdfs:label "mutation" ;
rdfs:comment "A change in a sequence or structure in comparison to a reference entity due to a insertion, deletion or substitution event." ;
rdfs:subClassOf obo:SO_0001059 .
a rdfs:Class ;
rdfs:label "Bioenergy" ;
rdfs:comment "Bioenergy is renewable energy made available from materials derived from biological sources. [AL 6.3.18, source Wikipedia https://en.wikipedia.org/wiki/Bioenergy]." ;
rdfs:subClassOf obo:PATO_0001021 .
obo:ENVO_00002030 a rdfs:Class ;
rdfs:label "aquatic biome" ;
rdfs:comment "A biome which is determined by a water body and which has ecological climax communities adapted to life in or on water." ;
rdfs:subClassOf obo:ENVO_00000428 , obo:ENVO_01001787 .
obo:CHEBI_26082 a rdfs:Class ;
rdfs:label "phosphorus molecular entity" ;
rdfs:subClassOf obo:CHEBI_33302 .
obo:CHEBI_25608 a rdfs:Class ;
rdfs:label "nucleoside phosphate" ;
rdfs:comment "A nucleobase-containing molecular entity that is a nucleoside in which one or more of the sugar hydroxy groups has been converted into a mono- or poly-phosphate. The term includes both nucleotides and non-nucleotide nucleoside phosphates." ;
rdfs:subClassOf obo:CHEBI_25703 , obo:CHEBI_37734 , obo:CHEBI_61120 .
obo:NCIT_C4873 a rdfs:Class ;
rdfs:label "Rare Disorder" ;
rdfs:comment "A non-neoplastic or neoplastic disorder that is uncommon." ;
rdfs:subClassOf obo:OGMS_0000031 .
obo:SO_0001026 a rdfs:Class ;
rdfs:label "genome" ;
rdfs:comment "A genome is the sum of genetic material within a cell or virion." ;
rdfs:subClassOf obo:SO_0001260 .
a rdfs:Class ;
rdfs:label "mental health" ;
rdfs:comment "The state wherein the person is well adjusted." ;
rdfs:subClassOf obo:BFO_0000016 .
obo:NCIT_C16622 a rdfs:Class ;
rdfs:label "Genetic Marker" ;
rdfs:comment "A segment of DNA with an identifiable physical location on a chromosome and whose inheritance can be followed." ;
rdfs:subClassOf obo:CHEBI_59163 .
obo:NCIT_C13445 a rdfs:Class ;
rdfs:label "Gene Feature" ;
rdfs:comment "The structural elements that comprise a gene or transcription unit. Gene structures include the transcription initiation site, the protein coding sequences, intervening sequences, and the transcription termination or polyadenylation sites as well as the regulatory elements (enhancers, silencers, and the promoter) that lie outside the boundaries of the transcribed unit." ;
rdfs:subClassOf obo:SO_0001411 .
a rdfs:Class ;
rdfs:label "FAIR"@en ;
rdfs:comment "A resource is FAIR if it is compliant with the FAIR principles, a set of guidelines to make data Findable, Accessible, Interoperable, and Re-usable. These guidelines are useful for those wishing to enhance the reusability of their data holdings. Distinct from peer initiatives that focus on the human scholar, the FAIR Principles put specific emphasis on enhancing the ability of machines to automatically find and use the data, in addition to supporting its reuse by individuals." ;
rdfs:subClassOf obo:BFO_0000019 .
obo:CHEBI_24432 a rdfs:Class ;
rdfs:label "biological role" ;
rdfs:comment "A role played by the molecular entity or part thereof within a biological context." ;
rdfs:subClassOf obo:BFO_0000023 .
obo:SO_0000934 a rdfs:Class ;
rdfs:label "miRNA_target_site" ;
rdfs:comment "A miRNA target site is a binding site where the molecule is a micro RNA." ;
rdfs:subClassOf obo:SO_0000409 .
obo:CHMO_0000140 a rdfs:Class ;
rdfs:label "reciprocal-space method" ;
rdfs:comment "Any detection or measurement method for a set of points in reciprocal space." ;
rdfs:subClassOf obo:OBI_0000070 .
obo:GO_0050794 a rdfs:Class ;
rdfs:label "regulation of cellular process" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level." ;
rdfs:subClassOf obo:GO_0050789 .
obo:CL_0000000 a rdfs:Class ;
rdfs:label "cell" ;
rdfs:comment "A material entity of anatomical origin (part of or deriving from an organism) that has as its parts a maximally connected cell compartment surrounded by a plasma membrane." ;
rdfs:subClassOf obo:UBERON_0000061 .
obo:MI_0000 a rdfs:Class ;
rdfs:label "molecular interaction" ;
rdfs:comment "Controlled vocabularies originally created for protein protein interactions, extended to other molecules interactions." ;
rdfs:subClassOf obo:GO_0008150 .
obo:IAO_0000309 a rdfs:Class ;
rdfs:label "diagram"@en ;
rdfs:comment "A figure that expresses one or more propositions"@en ;
rdfs:subClassOf obo:IAO_0000308 .
obo:GO_0031982 a rdfs:Class ;
rdfs:label "vesicle" ;
rdfs:comment "Any small, fluid-filled, spherical organelle enclosed by membrane." ;
rdfs:subClassOf obo:GO_0043227 .
obo:OBI_0000729 a rdfs:Class ;
rdfs:label "cloning plasmid" ;
rdfs:comment "A cloning plasmid is a plasmid that was engineered to contain a bacterial origin of replication, encodes for a selectable gene product and contains a cloning site."@en ;
rdfs:subClassOf obo:OBI_0000430 , obo:OBI_0000737 .
obo:SO_0001244 a rdfs:Class ;
rdfs:label "pre_miRNA" ;
rdfs:comment "The 60-70 nucleotide region remain after Drosha processing of the primary transcript, that folds back upon itself to form a hairpin structure." ;
rdfs:subClassOf obo:SO_0000835 .
obo:OBI_0000893 a rdfs:Class ;
rdfs:label "real time polymerase chain reaction assay" ;
rdfs:comment "An assay, based on the PCR, that amplifies and simultaneously quantifies a specific DNA molecule based on the use of complementary probes/primers. It enables both detection and quantification (as absolute number of copies or relative amount when normalized to DNA input or additional normalizing genes) of one or more specific sequences in a DNA sample."@en ;
rdfs:subClassOf obo:OBI_0002692 .
a rdfs:Class ;
rdfs:label "Genome analysis" ;
rdfs:comment "Study of genomic feature structure, variation, function and evolution at a genomic scale." ;
rdfs:subClassOf .
obo:MP_0000001 a rdfs:Class ;
rdfs:label "mammalian phenotype" ;
rdfs:comment "the observable morphological, physiological, behavioral and other characteristics of mammalian organisms that are manifested through development and lifespan" ;
rdfs:subClassOf obo:OGMS_0000023 .
obo:OAE_0000002 a rdfs:Class ;
rdfs:label "medical intervention" ;
rdfs:comment "medical intervention is a planned process that has the goal of diagnosing, preventing or relieving illness or injury." ;
rdfs:subClassOf obo:OBI_0000011 .
a rdfs:Class ;
rdfs:label "DNA sequence" ;
rdfs:comment "A DNA sequence." ;
rdfs:subClassOf .
obo:BFO_0000023 a rdfs:Class ;
rdfs:label "role"@en ;
rdfs:comment "A realizable entity the manifestation of which brings about some result or end that is not essential to a continuant in virtue of the kind of thing that it is but that can be served or participated in by that kind of continuant in some kinds of natural, social or institutional contexts."@en ;
rdfs:subClassOf obo:BFO_0000017 .
obo:GO_0016477 a rdfs:Class ;
rdfs:label "cell migration" ;
rdfs:comment "The controlled self-propelled movement of a cell from one site to a destination guided by molecular cues." ;
rdfs:subClassOf obo:GO_0009987 .
obo:UBERON_0005177 a rdfs:Class ;
rdfs:label "trunk region element" ;
rdfs:comment "An organ or element that part of the trunk region. The trunk region can be further subdividied into thoracic (including chest and thoracic cavity) and abdominal (including abdomen and pelbis) regions." ;
rdfs:subClassOf obo:UBERON_0000062 .
obo:NCIT_C18966 a rdfs:Class ;
rdfs:label "Protein Expression" ;
rdfs:comment "The biosynthesis of new (often sets of distinct, functionally related) protein products, usually involving new mRNA transcripts, typically in response to an activating stimulus." ;
rdfs:subClassOf obo:GO_0043043 .
obo:NCIT_C45275 a rdfs:Class ;
rdfs:label "Tracking" ;
rdfs:comment "The act or process of following a person, animal, or object through space or time." ;
rdfs:subClassOf obo:OBI_0000011 .
obo:GO_0043412 a rdfs:Class ;
rdfs:label "macromolecule modification" ;
rdfs:comment "The covalent alteration of one or more monomeric units in a polypeptide, polynucleotide, polysaccharide, or other biological macromolecule, resulting in a change in its properties." ;
rdfs:subClassOf obo:GO_0043170 .
obo:SO_0002247 a rdfs:Class ;
rdfs:label "sncRNA" ;
rdfs:comment "A non-coding RNA less than 200 nucleotides in length." ;
rdfs:subClassOf obo:SO_0000655 .
obo:CL_0002319 a rdfs:Class ;
rdfs:label "neural cell" ;
rdfs:comment "A cell that is part of the nervous system." ;
rdfs:subClassOf obo:CL_0000255 .
obo:IAO_0000572 a rdfs:Class ;
rdfs:label "documenting"@en ;
rdfs:comment "A planned process in which a document is created or added to by including the specified input in it."@en ;
rdfs:subClassOf obo:OBI_0000011 .
obo:GO_0010558 a rdfs:Class ;
rdfs:label "negative regulation of macromolecule biosynthetic process" ;
rdfs:comment "Any process that decreases the rate, frequency or extent of the chemical reactions and pathways resulting in the formation of a macromolecule, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass." ;
rdfs:subClassOf obo:GO_0009890 , obo:GO_0010556 , obo:GO_0010605 .
a rdfs:Class ;
rdfs:label "comparative genomic hybridization by array" ;
rdfs:comment "An assay in which changes in DNA sequence copy number are analysed using a microarray. For example the analysis of LOH in tumor cells vs a non diseased sample or the comparison of clinical isolated of disease causing bacteria." ;
rdfs:subClassOf .
obo:GO_0048856 a rdfs:Class ;
rdfs:label "anatomical structure development" ;
rdfs:comment "The biological process whose specific outcome is the progression of an anatomical structure from an initial condition to its mature state. This process begins with the formation of the structure and ends with the mature structure, whatever form that may be including its natural destruction. An anatomical structure is any biological entity that occupies space and is distinguished from its surroundings. Anatomical structures can be macroscopic such as a carpel, or microscopic such as an acrosome." ;
rdfs:subClassOf obo:GO_0032502 .
obo:NCIT_C17253 a rdfs:Class ;
rdfs:label "Viral Genome" ;
rdfs:comment "The total complement of hereditary material in a virus, which can be composed of either DNA or RNA." ;
rdfs:subClassOf obo:SO_0001026 .
obo:GO_0009306 a rdfs:Class ;
rdfs:label "protein secretion" ;
rdfs:comment "The controlled release of proteins from a cell." ;
rdfs:subClassOf obo:GO_0015031 , obo:GO_0032940 , obo:GO_0035592 .
obo:CHEBI_52214 a rdfs:Class ;
rdfs:label "ligand" ;
rdfs:comment "Any molecule or ion capable of binding to a central metal atom to form coordination complexes." ;
rdfs:subClassOf obo:CHEBI_51086 .
obo:GO_0008150 a rdfs:Class ;
rdfs:label "biological_process" ;
rdfs:comment "A biological process is the execution of a genetically-encoded biological module or program. It consists of all the steps required to achieve the specific biological objective of the module. A biological process is accomplished by a particular set of molecular functions carried out by specific gene products (or macromolecular complexes), often in a highly regulated manner and in a particular temporal sequence." ;
rdfs:subClassOf obo:BFO_0000015 .
a rdfs:Class ;
rdfs:label "ATC code" ;
rdfs:comment "Unique identifier of a drug conforming to the Anatomical Therapeutic Chemical (ATC) Classification System, a drug classification system controlled by the WHO Collaborating Centre for Drug Statistics Methodology (WHOCC)." ;
rdfs:subClassOf , .
a rdfs:Class ;
rdfs:label "aging"@en ;
rdfs:comment "A developmental process that is a deterioration and loss of function over time. Aging includes loss of functions such as resistance to disease, homeostasis, and fertility, as well as wear and tear. Aging includes cellular senescence, but is more inclusive. May precede death and may succeed developmental maturation." ;
rdfs:subClassOf obo:GO_0032502 .
obo:NCIT_C453 a rdfs:Class ;
rdfs:label "Recombinant DNA" ;
rdfs:comment "Biologically active DNA which has been formed by the in vitro joining of segments of DNA from different sources usually for the purpose of genetic manipulation." ;
rdfs:subClassOf obo:CHEBI_16991 .
obo:GO_0003674 a rdfs:Class ;
rdfs:label "molecular_function" ;
rdfs:comment "A molecular process that can be carried out by the action of a single macromolecular machine, usually via direct physical interactions with other molecular entities. Function in this sense denotes an action, or activity, that a gene product (or a complex) performs." ;
rdfs:subClassOf obo:BFO_0000034 .
obo:OBI_0001271 a rdfs:Class ;
rdfs:label "RNA-seq assay" ;
rdfs:comment "An RNA sequencing assay that determines an RNA sequence by analyzing the transcibed regions of the genome and or to quantitate transcript abundance."@en ;
rdfs:subClassOf obo:OBI_0001177 .
obo:CHEBI_33253 a rdfs:Class ;
rdfs:label "nucleon" ;
rdfs:comment "Heavy nuclear particle: proton or neutron." ;
rdfs:subClassOf obo:CHEBI_36347 .
obo:MP_0005382 a rdfs:Class ;
rdfs:label "craniofacial phenotype" ;
rdfs:comment "the observable morphological and physiological characteristics of the face or head of a mammalian organism that are manifested through development and lifespan" ;
rdfs:subClassOf obo:MP_0000001 .
obo:OBI_0001954 a rdfs:Class ;
rdfs:label "ChIP assay" ;
rdfs:comment "An assay in which portions of chromatin, the ordered and organized complex of DNA and its interaction partners that make up a chormosome, is extracted and purified by immunoprecipitation with antibodies or tags, and subsequently analyzed"@en ;
rdfs:subClassOf obo:OBI_0000070 .
a rdfs:Class ;
rdfs:label "drug interaction" ;
rdfs:comment "Alteration of the disposition and/or effect of a drug, owing to the presence of another factor such as a second drug, or food." ;
rdfs:subClassOf obo:MI_0000 .
obo:UBERON_0000105 a rdfs:Class ;
rdfs:label "life cycle stage" ;
rdfs:comment "A spatiotemporal region encompassing some part of the life cycle of an organism." ;
rdfs:subClassOf obo:UBERON_0000000 .
obo:SO_0000203 a rdfs:Class ;
rdfs:label "UTR" ;
rdfs:comment "Messenger RNA sequences that are untranslated and lie five prime or three prime to sequences which are translated." ;
rdfs:subClassOf obo:SO_0000836 .
obo:SO_0001956 a rdfs:Class ;
rdfs:label "protease_site" ;
rdfs:comment "A polypeptide_region that codes for a protease cleavage site." ;
rdfs:subClassOf obo:SO_0000839 .
obo:SO_0000771 a rdfs:Class ;
rdfs:label "QTL" ;
rdfs:comment "A quantitative trait locus (QTL) is a polymorphic locus which contains alleles that differentially affect the expression of a continuously distributed phenotypic trait. Usually it is a marker described by statistical association to quantitative variation in the particular phenotypic trait that is thought to be controlled by the cumulative action of alleles at multiple loci." ;
rdfs:subClassOf obo:SO_0001411 .
obo:SO_0001041 a rdfs:Class ;
rdfs:label "viral_sequence" ;
rdfs:comment "The region of nucleotide sequence of a virus, a submicroscopic particle that replicates by infecting a host cell." ;
rdfs:subClassOf obo:SO_0001037 .
obo:SO_0000745 a rdfs:Class ;
rdfs:label "chloroplast_sequence" ;
rdfs:comment "DNA belonging to the genome of a chloroplast, a green plastid for photosynthesis." ;
rdfs:subClassOf obo:SO_0000740 .
obo:NCIT_C13375 a rdfs:Class ;
rdfs:label "Chromosome Fragile Site" ;
rdfs:comment "Heritable sensitive regions of chromosomes which show up in vitro as non-staining bands. They are associated with chromosome breakage and other aberrations. No abnormal phenotype has been definitely identified with autosomal fragile sites, but some rare autosomal recessive disorders may be due to homozygosity for fragile sites. A fragile site on the X chromosome is associated with Fragile X Syndrome. Fragile sites are designated by the letters \"fra\" followed by the designation for the specific chromosome and locus." ;
rdfs:subClassOf obo:GO_0098687 .
obo:OBI_0000427 a rdfs:Class ;
rdfs:label "enzyme"@en ;
rdfs:comment """(protein or rna) or has_part (protein or rna) and
has_function some GO:0003824 (catalytic activity)"""@en ;
rdfs:subClassOf obo:BFO_0000040 .
a rdfs:Class ;
rdfs:label "EC number" ;
rdfs:comment "An Enzyme Commission (EC) number of an enzyme." ;
rdfs:subClassOf , .
obo:GO_0035592 a rdfs:Class ;
rdfs:label "establishment of protein localization to extracellular region" ;
rdfs:comment "The directed movement of a protein to a specific location within the extracellular region." ;
rdfs:subClassOf obo:GO_0045184 .
a rdfs:Class ;
rdfs:label "Molecule identifier" ;
rdfs:comment "Name or other identifier of a molecule." ;
rdfs:subClassOf .
obo:OBI_0600014 a rdfs:Class ;
rdfs:label "material component separation"@en ;
rdfs:comment "a material processing in which components of an input material become segregated in space"@en ;
rdfs:subClassOf obo:OBI_0000094 .
obo:OGMS_0000028 a rdfs:Class ;
rdfs:label "disease phenotype" ;
rdfs:comment "A clinically abnormal phenotype that is characteristic of a single disease."@en ;
rdfs:subClassOf obo:OGMS_0000023 .
obo:CHEBI_25212 a rdfs:Class ;
rdfs:label "metabolite" ;
rdfs:comment "Any intermediate or product resulting from metabolism. The term 'metabolite' subsumes the classes commonly known as primary and secondary metabolites." ;
rdfs:subClassOf obo:CHEBI_24432 .
a rdfs:Class ;
rdfs:label "Genome map" ;
rdfs:comment "Sequence map of a whole genome." ;
rdfs:subClassOf .
a rdfs:Class ;
rdfs:label "Text mining" ;
rdfs:comment "Process and analyse text (typically scientific literature) to extract information from it." ;
rdfs:subClassOf , .
obo:SO_0000253 a rdfs:Class ;
rdfs:label "tRNA" ;
rdfs:comment "Transfer RNA (tRNA) molecules are approximately 80 nucleotides in length. Their secondary structure includes four short double-helical elements and three loops (D, anti-codon, and T loops). Further hydrogen bonds mediate the characteristic L-shaped molecular structure. Transfer RNAs have two regions of fundamental functional importance: the anti-codon, which is responsible for specific mRNA codon recognition, and the 3' end, to which the tRNA's corresponding amino acid is attached (by aminoacyl-tRNA synthetases). Transfer RNAs cope with the degeneracy of the genetic code in two manners: having more than one tRNA (with a specific anti-codon) for a particular amino acid; and 'wobble' base-pairing, i.e. permitting non-standard base-pairing at the 3rd anti-codon position." ;
rdfs:subClassOf obo:SO_0002247 .
obo:BFO_0000016 a rdfs:Class ;
rdfs:label "disposition"@en ;
rdfs:subClassOf obo:BFO_0000017 .
obo:IAO_0000030 a rdfs:Class ;
rdfs:label "information entity" ;
rdfs:comment "An information entity is an entity that represents information about some other entity. For example, a measurement, a clustered data set." ;
rdfs:subClassOf obo:BFO_0000031 .
a rdfs:Class ;
rdfs:label "Gene name" ;
rdfs:comment "The name of a gene, (typically) assigned by a person and/or according to a naming scheme. It may contain white space characters and is typically more intuitive and readable than a gene symbol. It (typically) may be used to identify similar genes in different species and to derive a gene symbol." ;
rdfs:subClassOf , .
obo:OMIT_0028630 a rdfs:Class ;
rdfs:label "Non-Randomized Controlled Trials as Topic" ;
rdfs:subClassOf obo:OBI_0000066 .
obo:SO_0000112 a rdfs:Class ;
rdfs:label "primer" ;
rdfs:comment "An oligo to which new deoxyribonucleotides can be added by DNA polymerase." ;
rdfs:subClassOf obo:SO_0000696 .
obo:FMA_84795 a rdfs:Class ;
rdfs:label "Human leukocyte antigen complex" ;
rdfs:subClassOf obo:GO_0032991 .
obo:ENVO_00010483 a rdfs:Class ;
rdfs:label "environmental material" ;
rdfs:comment "A material entity which other material entities in an environmental system are primarily or partially composed of."@en ;
rdfs:subClassOf obo:BFO_0000040 .
obo:PW_0000001 a rdfs:Class ;
rdfs:label "pathway" ;
rdfs:comment "A pathway is a set of inter-connected reactions and interactions whose delineation and scope are used as a model for exploring and studying, describing and understanding the working of and relationships between biomolecules within a context." ;
rdfs:subClassOf obo:IAO_0000030 .
obo:NCIT_C18962 a rdfs:Class ;
rdfs:label "Protein Analysis" ;
rdfs:comment "Analysis of protein components in a sample. The most basic analysis involves determination of the mass or concentration of protein by any of a number of quantitative assays. Increased level of detail in the analysis requires resolution of a mixture into its component proteins. The characterization of a pure protein includes the determination of a number of its properties, among these, the molecular weight, isoelectric point, subunit composition, tryptic map, amino acid composition, amino acid sequence, hydrodynamics (s value, frictional coefficient, shape, aggregation state), thermodynamics (melting, folding, protein-protein interactions), and atomic structure (NMR, diffraction)." ;
rdfs:subClassOf .
obo:CHEBI_51087 a rdfs:Class ;
rdfs:label "protecting group" ;
rdfs:comment "A group that is introduced into a molecule by chemical modification of a functional group in order to obtain chemoselectivity in a subsequent chemical reaction." ;
rdfs:subClassOf obo:CHEBI_33232 .
obo:GO_0035195 a rdfs:Class ;
rdfs:label "miRNA-mediated post-transcriptional gene silencing" ;
rdfs:comment "A post-transcriptional gene silencing pathway in which regulatory microRNAs (miRNAs) elicit silencing of specific target genes. miRNAs are endogenous 21-24 nucleotide small RNAs processed from stem-loop RNA precursors (pre-miRNAs). Once incorporated into a RNA-induced silencing complex (RISC), miRNAs can downregulate protein production by either of two posttranscriptional mechanisms: endonucleolytic cleavage of the RNA (often mRNA) or mRNA translational repression, usually accompanied by poly-A tail shortening and subsequent degradation of the mRNA. miRNAs are present in all the animals and in plants, whereas siRNAs are present in lower animals and in plants." ;
rdfs:subClassOf obo:GO_0035194 .
obo:SO_0000330 a rdfs:Class ;
rdfs:label "conserved_region" ;
rdfs:comment "Region of sequence similarity by descent from a common ancestor." ;
rdfs:subClassOf obo:SO_0001410 .
obo:CHEBI_36347 a rdfs:Class ;
rdfs:label "nuclear particle" ;
rdfs:comment "A nucleus or any of its constituents in any of their energy states." ;
rdfs:subClassOf obo:CHEBI_36342 .
a rdfs:Class ;
rdfs:label "Compound identifier" ;
rdfs:comment "Identifier of an entry from a database of chemicals." ;
rdfs:subClassOf .
obo:OBI_0000725 a rdfs:Class ;
rdfs:label "host role" ;
rdfs:comment "host role is a role played by an organism and realized by providing nourishment, shelter or a means of reproduction to another organism within the organism playing the host role"@en ;
rdfs:subClassOf obo:BFO_0000023 .
obo:PATO_0001995 a rdfs:Class ;
rdfs:label "organismal quality" ;
rdfs:comment "A quality that inheres in an entire organism or part of an organism." ;
rdfs:subClassOf obo:PATO_0001241 .
obo:ENVO_01000049 a rdfs:Class ;
rdfs:label "marine coral reef biome" ;
rdfs:comment "The marine coral reef biome comprises constructional wave-resistant entities which are primarily built by corals and are often cemented together. The growth of these structures is aided by zooxanthellae, algae that are symbiotic with the reef-building corals." ;
rdfs:subClassOf obo:ENVO_01000029 .
obo:GO_0080090 a rdfs:Class ;
rdfs:label "regulation of primary metabolic process" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways within a cell or an organism involving those compounds formed as a part of the normal anabolic and catabolic processes. These processes take place in most, if not all, cells of the organism." ;
rdfs:subClassOf obo:GO_0019222 .
a rdfs:Class ;
rdfs:label "Atomic coordinate" ;
rdfs:comment "Cartesian coordinate of an atom (in a molecular structure)." ;
rdfs:subClassOf .
a rdfs:Class ;
rdfs:label "infant" ;
rdfs:subClassOf obo:UBERON_0000105 .
a rdfs:Class ;
rdfs:label "germplasm" ;
rdfs:comment "Germplasm is the living genetic resources such as seeds or tissue that is maintained for the purpose of animal and plant breeding, preservation, and other research uses. These resources may take the form of seed collections stored in seed banks, trees growing in nurseries, animal breeding lines maintained in animal breeding programs or gene banks, etc. Germplasm collections can range from collections of wild species to elite, domesticated breeding lines that have undergone extensive human selection." ;
rdfs:subClassOf obo:OBI_0000181 .
obo:SO_0001260 a rdfs:Class ;
rdfs:label "sequence_collection" ;
rdfs:comment "A collection of discontinuous sequences." ;
rdfs:subClassOf obo:IAO_0000030 .
a rdfs:Class ;
rdfs:label "Biobank" ;
rdfs:comment "Repositories of biological samples, typically human, for basic biological and clinical research." ;
rdfs:subClassOf obo:BFO_0000040 .
a rdfs:Class ;
rdfs:label "chromosomal aberration" ;
rdfs:comment "An irregularity in the number or structure of chromosomes, usually in the form of a gain (duplication), loss (deletion), exchange (translocation), or alteration in sequence (inversion) of genetic material." ;
rdfs:subClassOf .
obo:GO_0007127 a rdfs:Class ;
rdfs:label "meiosis I" ;
rdfs:comment "The first meiotic nuclear division in which homologous chromosomes are paired and segregated from each other, producing two haploid daughter nuclei." ;
rdfs:subClassOf obo:GO_0140013 .
obo:SO_0000289 a rdfs:Class ;
rdfs:label "microsatellite" ;
rdfs:comment "A repeat_region containing repeat_units of 2 to 10 bp repeated in tandem." ;
rdfs:subClassOf obo:SO_0000705 .
obo:CHEBI_36915 a rdfs:Class ;
rdfs:label "inorganic cation" ;
rdfs:subClassOf obo:CHEBI_36914 , obo:CHEBI_36916 .
obo:CHMO_0000591 a rdfs:Class ;
rdfs:label "nuclear magnetic resonance spectroscopy" ;
rdfs:comment "Spectroscopy where the energy states of spin-active nuclei placed in a static magnetic field are interrogated by inducing transitions between the states via radio frequency irradiation." ;
rdfs:subClassOf obo:CHMO_0001806 .
obo:CL_0002322 a rdfs:Class ;
rdfs:label "embryonic stem cell" ;
rdfs:comment "A stem cell of embryonic origin." ;
rdfs:subClassOf obo:CL_0000034 , obo:CL_0002321 .
obo:SO_0000833 a rdfs:Class ;
rdfs:label "transcript_region" ;
rdfs:comment "A region of a transcript." ;
rdfs:subClassOf obo:SO_0001411 .
obo:BFO_0000001 a rdfs:Class ;
rdfs:label "entity"@en .
obo:CHEBI_33285 a rdfs:Class ;
rdfs:label "heteroorganic entity" ;
rdfs:comment "A heteroorganic entity is an organic molecular entity in which carbon atoms or organic groups are bonded directly to one or more heteroatoms." ;
rdfs:subClassOf obo:CHEBI_50860 .
a rdfs:Class ;
rdfs:label "Proteolytic digest" ;
rdfs:comment "A protein sequence cleaved into peptide fragments (by enzymatic or chemical cleavage) with fragment masses." ;
rdfs:subClassOf obo:SO_0001260 .
a rdfs:Class ;
rdfs:label "Nucleic acid sequence" ;
rdfs:comment "One or more nucleic acid sequences, possibly with associated annotation." ;
rdfs:subClassOf obo:SO_0001411 .
a rdfs:Class ;
rdfs:label "literature curation"@en ;
rdfs:subClassOf obo:IAO_0000572 .
obo:T4FS_0000353 a rdfs:Class ;
rdfs:label "resource management"@en ;
rdfs:comment "Resource management is the efficient and effective development of an organization's resources when they are needed. Such resources may include the financial resources, inventory, human skills, production resources, or information technology (IT) and natural resources."@en ;
rdfs:subClassOf obo:T4FS_0000012 .
obo:SO_0000591 a rdfs:Class ;
rdfs:label "pseudoknot" ;
rdfs:comment "A tertiary structure in RNA where nucleotides in a loop form base pairs with a region of RNA downstream of the loop." ;
rdfs:subClassOf obo:SO_0001411 .
obo:MF_0000020 a rdfs:Class ;
rdfs:label "mental process" ;
rdfs:comment "A bodily process that occurs in the brain, and that can of itself be conscious, or can give rise to a process that can of itself be conscious or can give rise to behaviour." ;
rdfs:subClassOf obo:GO_0008150 .
a rdfs:Class ;
rdfs:label "Sequence cluster" ;
rdfs:comment "A set of sequences that have been clustered or otherwise classified as belonging to a group including (typically) sequence cluster information." ;
rdfs:subClassOf obo:SO_0001260 .
obo:GO_0042571 a rdfs:Class ;
rdfs:label "immunoglobulin complex, circulating" ;
rdfs:comment "An immunoglobulin complex that is secreted into extracellular space and found in mucosal areas or other tissues or circulating in the blood or lymph. In its canonical form, a circulating immunoglobulin complex is composed of two identical heavy chains and two identical light chains, held together by disulfide bonds. Some forms of are polymers of the basic structure and contain additional components such as J-chain and the secretory component." ;
rdfs:subClassOf obo:GO_0019814 .
obo:PRIDE_0000427 a rdfs:Class ;
rdfs:label "Top-down proteomics" ;
rdfs:comment "Top-down Proteomics is a method of protein identification that uses an ion trapping mass spectrometer to store an isolated protein ion for mass measurement and tandem mass spectrometry analysis. Top-down proteomics is capable of identifying unique proteoforms (the specific molecular form of the protein resulting from combinations of genetic variation, alternative splicing, and post-translational modifications) through the analysis of intact proteins. Both the intact and fragment ions masses of a protein can be measured. This approach routinely allows for 100% sequence coverage and full characterization of proteoforms. The potential for achieving full protein characterization has made the Top Down mass spectrometry approach extremely useful for analysis of single proteins or simple mixtures of significant biological interest." ;
rdfs:subClassOf obo:OBI_0000470 .
obo:NCIT_C66892 a rdfs:Class ;
rdfs:label "Natural Product" ;
rdfs:comment "Any whole or part of a plant (including plant exudates), animal or microorganism that is unprocessed (raw material), or that has been processed, pulverized or extracted. Many of the natural products have some biological and/or pharmacological activity or are used for a specific purpose, not necessarily medicinal (food, aroma therapy, research and etc.). This class does not include any individual substance derived from plants/animals or other organisms with specific pharmacologic activity (See Drug, Natural Product)." ;
rdfs:subClassOf obo:BFO_0000040 .
obo:ENVO_02500000 a rdfs:Class ;
rdfs:label "environmental system process"@en ;
rdfs:comment "A process in which includes the components of an environmental system as participants." ;
rdfs:subClassOf obo:BFO_0000015 .
obo:GO_0003824 a rdfs:Class ;
rdfs:label "catalytic activity" ;
rdfs:comment "Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic." ;
rdfs:subClassOf obo:GO_0003674 .
a rdfs:Class ;
rdfs:label "Peptide property" ;
rdfs:comment "Data concerning small peptides." ;
rdfs:subClassOf .
a rdfs:Class ;
rdfs:label "Structure-based sequence alignment" ;
rdfs:comment "Align molecular sequences using sequence and structural information." ;
rdfs:subClassOf obo:OBI_0002567 .
obo:OBI_0400169 a rdfs:Class ;
rdfs:label "microscope" ;
rdfs:comment "A microscope is an instrument which magnifies the view on objects (too small to be viewed by the naked eye) under increased resolution. A microscope can be an optical instrument but also and electronic instrument. There are various kind of optical microscopes, e.g confocal microscope, epifluoresence microscope)"@en ;
rdfs:subClassOf obo:OBI_0000398 .
a rdfs:Class ;
rdfs:label "Post-translational modification site prediction" ;
rdfs:comment "Predict post-translation modification sites in protein sequences." ;
rdfs:subClassOf .
obo:UBERON_0019319 a rdfs:Class ;
rdfs:label "exocrine gland of integumental system" ;
rdfs:comment "An exocrine gland that is part of a integumental system." ;
rdfs:subClassOf obo:UBERON_0002365 .
obo:CL_0000404 a rdfs:Class ;
rdfs:label "electrically signaling cell" ;
rdfs:comment "A cell that initiates an electrical signal and passes that signal to another cell." ;
rdfs:subClassOf obo:CL_0000211 .
obo:CHEBI_18059 a rdfs:Class ;
rdfs:label "lipid" ;
rdfs:comment "'Lipids' is a loosely defined term for substances of biological origin that are soluble in nonpolar solvents. They consist of saponifiable lipids, such as glycerides (fats and oils) and phospholipids, as well as nonsaponifiable lipids, principally steroids." ;
rdfs:subClassOf obo:CHEBI_50860 .
a rdfs:Class ;
rdfs:label "Data acquisition" ;
rdfs:comment "The acquisition of data, typically measurements of physical systems using any type of sampling system, or by another other means." ;
rdfs:subClassOf obo:OBI_0000011 .
a rdfs:Class ;
rdfs:label "Protein accession" ;
rdfs:comment "Accession of a protein deposited in a database." ;
rdfs:subClassOf .
a rdfs:Class ;
rdfs:label "chemical-disease association"@en ;
rdfs:subClassOf obo:MI_0914 .
obo:ENVO_01000024 a rdfs:Class ;
rdfs:label "marine benthic biome" ;
rdfs:comment "The marine benthic biome (benthic meaning 'bottom') encompasses the seafloor and includes such areas as shores, littoral or intertidal areas, marine coral reefs, and the deep seabed." ;
rdfs:subClassOf obo:ENVO_00000447 .
obo:OMP_0000197 a rdfs:Class ;
rdfs:label "microbe-host interaction phenotype" ;
rdfs:comment "A microbial phenotype related to the interactions between a microbe and its host(s)." ;
rdfs:subClassOf obo:OGMS_0000023 .
obo:OMIT_0028415 a rdfs:Class ;
rdfs:label "Intrinsically Disordered Proteins" ;
rdfs:subClassOf obo:PR_000000001 .
obo:SO_0001683 a rdfs:Class ;
rdfs:label "sequence_motif" ;
rdfs:comment "A sequence motif is a nucleotide or amino-acid sequence pattern that may have biological significance." ;
rdfs:subClassOf obo:SO_0001411 .
obo:DRON_00000001 a rdfs:Class ;
rdfs:label "clinical drug role"@en ;
rdfs:comment "A role of a material entity to prevent, diagnose, treat, or study disease and/or its effects."@en ;
rdfs:subClassOf obo:BFO_0000023 .
a rdfs:Class ;
rdfs:label "Operon prediction" ;
rdfs:comment "Find operons (operators, promoters and genes) in bacteria genes." ;
rdfs:subClassOf .
obo:GO_0005634 a rdfs:Class ;
rdfs:label "nucleus" ;
rdfs:comment "A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent." ;
rdfs:subClassOf obo:GO_0043231 .
obo:GO_0016310 a rdfs:Class ;
rdfs:label "phosphorylation" ;
rdfs:comment "The process of introducing a phosphate group into a molecule, usually with the formation of a phosphoric ester, a phosphoric anhydride or a phosphoric amide." ;
rdfs:subClassOf obo:GO_0008152 .
obo:SO_0001000 a rdfs:Class ;
rdfs:label "cytosolic_16S_rRNA" ;
rdfs:comment "Cytosolic 16S rRNA is an RNA component of the small subunit of cytosolic ribosomes in prokaryotes." ;
rdfs:subClassOf obo:SO_0000655 .
obo:OGMS_0000093 a rdfs:Class ;
rdfs:label "prognosis" ;
rdfs:comment "A hypothesis about some future part of a disease course."@en ;
rdfs:subClassOf obo:IAO_0000027 .
obo:PATO_0000051 a rdfs:Class ;
rdfs:label "morphology" ;
rdfs:comment "A quality of a single physical entity inhering in the bearer by virtue of the bearer's size or shape or structure." ;
rdfs:subClassOf obo:PATO_0001241 .
obo:SO_0001411 a rdfs:Class ;
rdfs:label "biological_region" ;
rdfs:comment "A region defined by its disposition to be involved in a biological process." ;
rdfs:subClassOf obo:SO_0000001 .
obo:CHEBI_36914 a rdfs:Class ;
rdfs:label "inorganic ion" ;
rdfs:subClassOf obo:CHEBI_24835 , obo:CHEBI_24870 .
obo:CL_0000988 a rdfs:Class ;
rdfs:label "hematopoietic cell" ;
rdfs:comment "A cell of a hematopoietic lineage." ;
rdfs:subClassOf obo:CL_0000000 .
obo:OBI_0001515 a rdfs:Class ;
rdfs:label "material maintenance service" ;
rdfs:comment "A material processing service in which a service provider makes physical modifications to a specified input material, such that at least one of the specified outputs of this process is a modified version of a specified input material."@en ;
rdfs:subClassOf obo:OBI_0001528 .
obo:OBI_0000423 a rdfs:Class ;
rdfs:label "extract"@en ;
rdfs:comment "an extract is a material entity which results from an extraction process"@en ;
rdfs:subClassOf obo:OBI_0000047 .
obo:BFO_0000015 a rdfs:Class ;
rdfs:label "process" ;
rdfs:comment "A process is an entity that exists in time by occurring or happening, has temporal parts and always involves and depends on some entity during the time it occurs." ;
rdfs:subClassOf obo:BFO_0000003 .
obo:OBI_0000454 a rdfs:Class ;
rdfs:label "extracellular electrophysiology recording assay" ;
rdfs:comment "An electrophysiology assay where the recording location of the electrode is extracellular."@en ;
rdfs:subClassOf obo:OBI_0002176 .
obo:OBI_0600053 a rdfs:Class ;
rdfs:label "electrophoresis"@en ;
rdfs:comment "a protocol application that uses an electrical potential to move material through a defined matrix in order to separate it by its resistance to movement and its charge"@en ;
rdfs:subClassOf obo:OBI_0600014 .
obo:CLO_0037280 a rdfs:Class ;
rdfs:label "human embryonic stem cell line cell"@en ;
rdfs:subClassOf obo:CLO_0037279 .
obo:MI_2030 a rdfs:Class ;
rdfs:label "isoelectric point" ;
rdfs:comment "The isoelectric point (pI) is the pH at which a particular molecule or surface carries no net electrical charge. For an amino acid with only one amine and one carboxyl group, the pI can be calculated from the pKas of this molecule." ;
rdfs:subClassOf .
obo:GO_0006810 a rdfs:Class ;
rdfs:label "transport" ;
rdfs:comment "The directed movement of substances (such as macromolecules, small molecules, ions) or cellular components (such as complexes and organelles) into, out of or within a cell, or between cells, or within a multicellular organism by means of some agent such as a transporter or a transporter complex, a pore or a motor protein." ;
rdfs:subClassOf obo:GO_0051234 .
obo:GO_1903046 a rdfs:Class ;
rdfs:label "meiotic cell cycle process" ;
rdfs:comment "A process that is part of the meiotic cell cycle." ;
rdfs:subClassOf obo:GO_0009987 .
a rdfs:Class ;
rdfs:label "Resource metadata" ;
rdfs:comment "Data concerning or describing some core computational resource, as distinct from primary data. This includes metadata on the origin, source, history, ownership or location of some thing." ;
rdfs:subClassOf obo:IAO_0000088 .
obo:OBI_0000424 a rdfs:Class ;
rdfs:label "transcription profiling assay" ;
rdfs:comment "An assay that determines gene expression and transcription activity using ribonucleic acids collected from a material entity."@en ;
rdfs:subClassOf obo:OBI_0000070 .
obo:FBcv_0003040 a rdfs:Class ;
rdfs:label "gene model annotation" ;
rdfs:comment "A project that constructs models describing the set of transcripts and polypeptides encoded by some group of genes." ;
rdfs:subClassOf obo:OBI_0200000 .
obo:DOID_863 a rdfs:Class ;
rdfs:label "nervous system disease"@en ;
rdfs:comment "A disease of anatomical entity that is located_in the central nervous system or located_in the peripheral nervous system."@en ;
rdfs:subClassOf obo:OGMS_0000031 .
obo:OBI_0001248 a rdfs:Class ;
rdfs:label "ChIP-chip assay" ;
rdfs:comment "An assay in which chromatin is immunoprecipitated and subsequently analyzed using a DNA microarray to identify which parts of DNA are part of the isolated chromatin"@en ;
rdfs:subClassOf obo:OBI_0001954 .
obo:IAO_0000088 a rdfs:Class ;
rdfs:label "report"@en ;
rdfs:comment "A document assembled by an author for the purpose of providing information for the audience. A report is the output of a documenting process and has the objective to be consumed by a specific audience. Topic of the report is on something that has completed. A report is not a single figure. Examples of reports are journal article, patent application, grant progress report, case report (not patient record)."@en ;
rdfs:subClassOf obo:IAO_0000310 .
obo:CHEBI_78616 a rdfs:Class ;
rdfs:label "carbohydrates and carbohydrate derivatives" ;
rdfs:comment "Any organooxygen compound that is a polyhydroxy-aldehyde or -ketone, or a compound derived from one. Carbohydrates contain only carbon, hydrogen and oxygen and usually have an empirical formula Cm(H2O)n; carbohydrate derivatives may contain other elements by substitution or condensation." ;
rdfs:subClassOf obo:CHEBI_36963 .
obo:BFO_0000004 a rdfs:Class ;
rdfs:label "independent continuant"@en ;
rdfs:comment "b is an independent continuant = Def. b is a continuant which is such that there is no c and no t such that b s-depends_on c at t. (axiom label in BFO2 Reference: [017-002])"@en ;
rdfs:subClassOf obo:BFO_0000002 .
obo:SO_0000736 a rdfs:Class ;
rdfs:label "organelle_sequence" ;
rdfs:comment "A sequence of DNA that originates from a an organelle." ;
rdfs:subClassOf obo:SO_0000400 .
obo:OBI_0400147 a rdfs:Class ;
rdfs:label "microarray" ;
rdfs:comment "A processed material that is made to be used in an analyte assay. It consists of a physical immobilisation matrix in which substances that bind the analyte are placed in regular spatial position."@en ;
rdfs:subClassOf obo:OBI_0001865 .
a rdfs:Class ;
rdfs:label "experimental process" ;
rdfs:comment "A process performed as part of an experiment or wider study, i.e. intentionally designed." ;
rdfs:subClassOf obo:OBI_0000011 .
obo:GO_1901873 a rdfs:Class ;
rdfs:label "regulation of post-translational protein modification" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of post-translational protein modification." ;
rdfs:subClassOf obo:GO_0051246 .
obo:T4FS_0000012 a rdfs:Class ;
rdfs:label "data stewardship activity"@en ;
rdfs:comment "A specific deed, action, function or sphere of action in relation with the role of data stewardship"@en ;
rdfs:subClassOf obo:BFO_0000015 .
obo:NCIT_C18106 a rdfs:Class ;
rdfs:label "Receptor" ;
rdfs:comment "A protein located on the cell surface, or in the cytoplasm, that binds to a specific signaling factor, such as a hormone, antigen, or neurotransmitter, causing a conformational and functional change in the receptor molecule. The ligand-bound receptor then alters its interaction with target molecules, which leads to changes in cellular physiology through modification of the activity of one or more signal transduction pathways." ;
rdfs:subClassOf obo:GO_0005622 .
a rdfs:Class ;
rdfs:label "Molecule name" ;
rdfs:comment "Name of a specific molecule." ;
rdfs:subClassOf , .
obo:OBI_0002186 a rdfs:Class ;
rdfs:label "electroencephalography" ;
rdfs:comment "An extracellular electrophysiology assay where electrodes are mounted outside the brain (either on the surface of the scalp on onto the brain surface itself during surgery) to measure the electrical field over the external surface."@en ;
rdfs:subClassOf obo:OBI_0000454 .
obo:DOID_331 a rdfs:Class ;
rdfs:label "central nervous system disease"@en ;
rdfs:comment "A nervous system disease that affects either the spinal cord (myelopathy) or brain (encephalopathy) of the central nervous system."@en ;
rdfs:subClassOf obo:DOID_863 .
obo:CHEBI_25710 a rdfs:Class ;
rdfs:label "organophosphorus compound" ;
rdfs:comment "An organophosphorus compound is formally a compound containing at least one carbon-phosphorus bond, but the term is often extended to include esters and thioesters." ;
rdfs:subClassOf obo:CHEBI_26082 , obo:CHEBI_33285 .
obo:UBERON_0002405 a rdfs:Class ;
rdfs:label "immune system" ;
rdfs:comment "Anatomical system that protects the body from foreign substances, cells, and tissues by producing the immune response and that includes especially the thymus, spleen, lymphoid tissue, lymphocytes including the B cells and T cells, and antibodies." ;
rdfs:subClassOf obo:UBERON_0000465 .
obo:DOID_162 a rdfs:Class ;
rdfs:label "cancer"@en ;
rdfs:comment "A disease of cellular proliferation that is malignant and primary, characterized by uncontrolled cellular proliferation, local cell invasion and metastasis."@en ;
rdfs:subClassOf obo:OGMS_0000031 .
a rdfs:Class ;
rdfs:label "Nucleic acid sequence analysis" ;
rdfs:comment "Analyse a nucleic acid sequence (using methods that are only applicable to nucleic acid sequences)." ;
rdfs:subClassOf .
obo:CHEBI_23367 a rdfs:Class ;
rdfs:label "molecular entity" ;
rdfs:comment "Any constitutionally or isotopically distinct atom, molecule, ion, ion pair, radical, radical ion, complex, conformer etc., identifiable as a separately distinguishable entity." ;
rdfs:subClassOf obo:CHEBI_24431 .
a rdfs:Class ;
rdfs:label "Validation" ;
rdfs:comment "Validate some data." ;
rdfs:subClassOf .
obo:GO_0050890 a rdfs:Class ;
rdfs:label "cognition" ;
rdfs:comment "The operation of the mind by which an organism becomes aware of objects of thought or perception; it includes the mental activities associated with thinking, learning, and memory." ;
rdfs:subClassOf obo:GO_0050877 .
obo:CHEBI_33893 a rdfs:Class ;
rdfs:label "reagent" ;
rdfs:comment "A substance used in a chemical reaction to detect, measure, examine, or produce other substances." ;
rdfs:subClassOf obo:CHEBI_33232 .
obo:CL_0000145 a rdfs:Class ;
rdfs:label "professional antigen presenting cell" ;
rdfs:comment "A cell capable of processing and presenting lipid and protein antigens to T cells in order to initiate an immune response." ;
rdfs:subClassOf obo:CL_0000738 .
obo:CHEBI_33302 a rdfs:Class ;
rdfs:label "pnictogen molecular entity" ;
rdfs:comment "A p-block molecular entity containing any pnictogen." ;
rdfs:subClassOf obo:CHEBI_33675 .
obo:GO_0048513 a rdfs:Class ;
rdfs:label "animal organ development" ;
rdfs:comment "Development of a tissue or tissues that work together to perform a specific function or functions. Development pertains to the process whose specific outcome is the progression of a structure over time, from its formation to the mature structure. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions." ;
rdfs:subClassOf obo:GO_0048856 .
a rdfs:Class ;
rdfs:label "Raw microarray data" ;
rdfs:comment "Raw data (typically MIAME-compliant) for hybridisations from a microarray experiment." ;
rdfs:subClassOf , .
obo:CHEBI_33281 a rdfs:Class ;
rdfs:label "antimicrobial agent" ;
rdfs:comment "A substance that kills or slows the growth of microorganisms, including bacteria, viruses, fungi and protozoans." ;
rdfs:subClassOf obo:CHEBI_24432 .
obo:CHMO_0000067 a rdfs:Class ;
rdfs:label "microscopy" ;
rdfs:comment "Any technique where a microscope is used to view a small object (or specimen) by producing a magnified image." ;
rdfs:subClassOf obo:OBI_0000185 .
a rdfs:Class ;
rdfs:label "Prediction and recognition" ;
rdfs:comment "Predict, recognise, detect or identify some properties of a biomolecule." ;
rdfs:subClassOf .
obo:CLO_0000001 a rdfs:Class ;
rdfs:label "cell line cell" ;
rdfs:subClassOf obo:OBI_0001866 .
obo:CHEBI_15358 a rdfs:Class ;
rdfs:label "histone" ;
rdfs:subClassOf obo:CHEBI_33695 .
obo:CHEBI_25367 a rdfs:Class ;
rdfs:label "molecule" ;
rdfs:comment "Any polyatomic entity that is an electrically neutral entity consisting of more than one atom." ;
rdfs:subClassOf obo:CHEBI_36357 .
obo:OBI_0002567 a rdfs:Class ;
rdfs:label "sequence alignment" ;
rdfs:comment "A data transformation in which one or more sequences (reads) are positioned on a reference sequence template (often a reference set of genes), according to the genetic base-pairing paradigm."@en ;
rdfs:subClassOf obo:OBI_0200187 .
obo:FBcv_0003077 a rdfs:Class ;
rdfs:label "RNAi screen" ;
rdfs:comment "An assay that uses a panel of RNA interference (RNAi) reagents to systematically knockdown a large set of genes, one at a time, to identify those that are involved in some biological process." ;
rdfs:subClassOf obo:OBI_0000070 .
obo:OMIT_0010354 a rdfs:Class ;
rdfs:label "Natural Language Processing" ;
rdfs:subClassOf obo:IAO_0000064 .
a rdfs:Class ;
rdfs:label "genomic measurement" ;
rdfs:comment "Is a quantification of some aspect of the genome, e.g. copy number variation at some locus." ;
rdfs:subClassOf .
a rdfs:Class ;
rdfs:label "Annotation" ;
rdfs:comment "Annotate an entity (typically a biological or biomedical database entity) with terms from a controlled vocabulary." ;
rdfs:subClassOf .
obo:OBI_1110122 a rdfs:Class ;
rdfs:label "pathologic process"@en ;
rdfs:comment "abnormal, harmful processes caused by or associated with a disease"@en ;
rdfs:subClassOf obo:GO_0008150 .
a rdfs:Class ;
rdfs:label "cis" ;
rdfs:comment """Positional relationship between entities on the same strand (e.g. in DNA), or on the same side.
""" ;
rdfs:subClassOf obo:IAO_0000030 .
a rdfs:Class ;
rdfs:label "Sequence length" ;
rdfs:comment "The size (length) of a sequence, subsequence or region in a sequence, or range(s) of lengths." ;
rdfs:subClassOf obo:SO_0000400 .
obo:SO_0000696 a rdfs:Class ;
rdfs:label "oligo" ;
rdfs:comment "A short oligonucleotide sequence, of length on the order of 10's of bases; either single or double stranded." ;
rdfs:subClassOf obo:SO_0000001 .
obo:CHEBI_33711 a rdfs:Class ;
rdfs:label "C-terminal amino-acid residue" ;
rdfs:comment "The residue in a peptide that has a free carboxyl group, or at least does not acylate another amino-acid residue, is called C-terminal." ;
rdfs:subClassOf obo:CHEBI_33708 .
a rdfs:Class ;
rdfs:label "obsolete_mitochondrial disease" ;
rdfs:subClassOf obo:OGMS_0000031 .
obo:CL_0000723 a rdfs:Class ;
rdfs:label "somatic stem cell" ;
rdfs:comment "A stem cell that can give rise to cell types of the body other than those of the germ-line." ;
rdfs:subClassOf obo:CL_0000034 .
obo:NCIT_C64862 a rdfs:Class ;
rdfs:label "Diffusion Tensor Imaging" ;
rdfs:comment "A type of diffusion-weighted magnetic resonance imaging (DW-MRI) that maps the diffusion of water in three dimensions, the principal purpose of which is to image the white matter of the brain, specifically measuring the anisotropy, location, and orientation of the neural tracts, which can demonstrate microstructural changes or differences with neuropathology and treatment." ;
rdfs:subClassOf obo:NCIT_C16809 .
a rdfs:Class ;
rdfs:label "genetic modification" ;
rdfs:comment "A genetic modification of the genome of an organism which may occur naturally by spontaneous mutation, or be introduced by some experimental means. Examples of genetic modification include specification of a transgene or the gene knocked-out or details of transient transfection." ;
rdfs:subClassOf obo:BFO_0000015 .
obo:OBI_0000443 a rdfs:Class ;
rdfs:label "analyte assay" ;
rdfs:comment "An assay with the objective to capture information about the presence, concentration, or amount of an analyte in an evaluant."@en ;
rdfs:subClassOf obo:OBI_0000070 .
a rdfs:Class ;
rdfs:label "Expression data" ;
rdfs:comment "Image, hybridisation or some other data arising from a study of feature/molecule expression, typically profiling or quantification." ;
rdfs:subClassOf obo:CHMO_0000793 .
a rdfs:Class ;
rdfs:label "drug dependence" ;
rdfs:comment "Drug dependence - replaced the term \"drug addiction\" and is defined as a state, psychic and sometimes also physical, resulting from the interaction between a living organism and a drug, characterized by behavioral and other responses that always include a compulsion to take the drug on a continuous or periodic basis in order to experience its psychic effects, and sometimes to avoid the discomfort of its absence. Tolerance may or may not be present. A person may be dependent on more than one drug." ;
rdfs:subClassOf obo:OGMS_0000031 .
a rdfs:Class ;
rdfs:label "Agricultural products" ;
rdfs:comment "Products in their original state or processed enough to be prepared for marketing." ;
rdfs:subClassOf obo:NCIT_C66892 .
a rdfs:Class ;
rdfs:label "Sequence visualisation" ;
rdfs:comment "Visualise, format or render a molecular sequence or sequences such as a sequence alignment, possibly with sequence features or properties shown." ;
rdfs:subClassOf .
obo:OBI_0000073 a rdfs:Class ;
rdfs:label "sample preparation for assay"@en ;
rdfs:comment "A sample_preparation_for_assay is a protocol_application including material_enrollments and biomaterial_transformations. definition_source: OBI."@en ;
rdfs:subClassOf obo:OBI_0000094 .
obo:CMO_0000000 a rdfs:Class ;
rdfs:label "clinical measurement" ;
rdfs:comment "A quantitative or qualitative value which is the result of an act of assessing a morphological or physiological state or property in a single individual or sample or a group of individuals or samples, based on direct observation or experimental manipulation." ;
rdfs:subClassOf .
a rdfs:Class ;
rdfs:label "Chimera detection" ;
rdfs:comment "Detects chimeric sequences (chimeras) from a sequence alignment." ;
rdfs:subClassOf .
obo:OBI_0001986 a rdfs:Class ;
rdfs:label "immunohistochemistry" ;
rdfs:comment "An immunostaining assay to detect and potentially localize antigens within the cells of a tissue section."@en ;
rdfs:subClassOf obo:OBI_0001632 .
obo:CHEBI_24431 a rdfs:Class ;
rdfs:label "chemical entity" ;
rdfs:comment "A chemical entity is a physical entity of interest in chemistry including molecular entities, parts thereof, and chemical substances." ;
rdfs:subClassOf obo:BFO_0000030 .
obo:CL_0002321 a rdfs:Class ;
rdfs:label "embryonic cell (metazoa)" ;
rdfs:comment "A cell of the embryo." ;
rdfs:subClassOf obo:CL_0000000 .
obo:GO_0051087 a rdfs:Class ;
rdfs:label "protein-folding chaperone binding" ;
rdfs:comment "Binding to a chaperone protein, a class of proteins that bind to nascent or unfolded polypeptides and ensure correct folding or transport." ;
rdfs:subClassOf obo:GO_0005515 .
obo:IAO_0000104 a rdfs:Class ;
rdfs:label "plan specification"@en ;
rdfs:comment "A directive information entity with action specifications and objective specifications as parts, and that may be concretized as a realizable entity that, if realized, is realized in a process in which the bearer tries to achieve the objectives by taking the actions specified."@en ;
rdfs:subClassOf obo:IAO_0000033 .
obo:OBI_0000680 a rdfs:Class ;
rdfs:label "whole organism preparation" ;
rdfs:comment "A material entity which is the output of a process in which one or more whole organisms are prepared in a way to make it easier to study them, and in which the great majority of organismal parts are maintained"@en ;
rdfs:subClassOf obo:NCIT_C70699 .
obo:GO_0006605 a rdfs:Class ;
rdfs:label "protein targeting" ;
rdfs:comment "The process of targeting specific proteins to particular regions of the cell, typically membrane-bounded subcellular organelles. Usually requires an organelle specific protein sequence motif." ;
rdfs:subClassOf obo:GO_0045184 .
obo:CHMO_0000104 a rdfs:Class ;
rdfs:label "bright-field microscopy" ;
rdfs:comment "Microscopy where the specimen is illuminated with light transmitted from a source on the opposite side of the specimen from the objective." ;
rdfs:subClassOf obo:CHMO_0000102 .
obo:GO_0019538 a rdfs:Class ;
rdfs:label "protein metabolic process" ;
rdfs:comment "The chemical reactions and pathways involving a protein. Includes protein modification." ;
rdfs:subClassOf obo:GO_0043170 , obo:GO_0044238 .
obo:OMIT_0018868 a rdfs:Class ;
rdfs:label "Founder Effect" ;
rdfs:subClassOf obo:SO_0001059 .
obo:GO_0051301 a rdfs:Class ;
rdfs:label "cell division" ;
rdfs:comment "The process resulting in division and partitioning of components of a cell to form more cells; may or may not be accompanied by the physical separation of a cell into distinct, individually membrane-bounded daughter cells." ;
rdfs:subClassOf obo:GO_0009987 .
obo:ENVO_01001082 a rdfs:Class ;
rdfs:label "climate"@en ;
rdfs:comment "The disposition of an environmental system, particularly those influencing atmospheres, to manifest a cyclic pattern of weather over time." ;
rdfs:subClassOf obo:ENVO_01000452 .
obo:ENVO_03000043 a rdfs:Class ;
rdfs:label "material transformation process"@en ;
rdfs:comment "A process during which a portion of some environmental material is converted into a different material or a collection of materials." ;
rdfs:subClassOf obo:ENVO_02500000 .
obo:GO_0005216 a rdfs:Class ;
rdfs:label "monoatomic ion channel activity" ;
rdfs:comment "Enables the facilitated diffusion of a monoatomic ion (by an energy-independent process) by passage through a transmembrane aqueous pore or channel without evidence for a carrier-mediated mechanism. May be either selective (it enables passage of a specific ion only) or non-selective (it enables passage of two or more ions of same charge but different size)." ;
rdfs:subClassOf obo:GO_0003674 .
obo:CHEBI_33260 a rdfs:Class ;
rdfs:label "elemental hydrogen" ;
rdfs:subClassOf obo:CHEBI_24835 , obo:CHEBI_33259 , obo:CHEBI_33579 .
obo:OBI_0000011 a rdfs:Class ;
rdfs:label "planned process" ;
rdfs:comment "A processual entity that realizes a plan which is the concretization of a plan specification."@en ;
rdfs:subClassOf obo:BFO_0000015 .
a rdfs:Class ;
rdfs:label "Sustainability" ;
rdfs:comment "The ability of a process or human activity to meet present needs but maintain natural resources and leave the environment in good order for future generations." ;
rdfs:subClassOf obo:PATO_0001018 .
obo:ENVO_01000452 a rdfs:Class ;
rdfs:label "environmental disposition" ;
rdfs:comment "A disposition which is realised by an environmental system or system parts thereof." ;
rdfs:subClassOf obo:BFO_0000016 .
obo:OBI_0001985 a rdfs:Class ;
rdfs:label "microarray assay" ;
rdfs:comment "An analyte assay where binding of the analyte to immobilized matrix is measured."@en ;
rdfs:subClassOf obo:OBI_0000443 .
obo:NCIT_C68821 a rdfs:Class ;
rdfs:label "Regulation" ;
rdfs:comment "A rule or order issued by an authority stating what may or may not be done or how something must be done." ;
rdfs:subClassOf obo:IAO_0000310 .
obo:NCBITaxon_408172 a rdfs:Class ;
rdfs:label "marine metagenome" ;
rdfs:subClassOf obo:OMIT_0026082 .
obo:GO_0006412 a rdfs:Class ;
rdfs:label "translation" ;
rdfs:comment "The cellular metabolic process in which a protein is formed, using the sequence of a mature mRNA or circRNA molecule to specify the sequence of amino acids in a polypeptide chain. Translation is mediated by the ribosome, and begins with the formation of a ternary complex between aminoacylated initiator methionine tRNA, GTP, and initiation factor 2, which subsequently associates with the small subunit of the ribosome and an mRNA or circRNA. Translation ends with the release of a polypeptide chain from the ribosome." ;
rdfs:subClassOf obo:GO_0009059 , obo:GO_0019538 .
obo:CL_0000540 a rdfs:Class ;
rdfs:label "neuron" ;
rdfs:comment "The basic cellular unit of nervous tissue. Each neuron consists of a body, an axon, and dendrites. Their purpose is to receive, conduct, and transmit impulses in the nervous system." ;
rdfs:subClassOf obo:CL_0000393 , obo:CL_0000404 , obo:CL_0002319 .
obo:SO_0000178 a rdfs:Class ;
rdfs:label "operon" ;
rdfs:comment "The DNA region of a group of adjacent genes whose transcription is coordinated on one or several mutually overlapping transcription units transcribed in the same direction and sharing at least one gene." ;
rdfs:subClassOf obo:SO_0005855 .
obo:OMIT_0001480 a rdfs:Class ;
rdfs:label "Machine Learning" ;
rdfs:comment "Machine learning is an algorithm or set of algorithms which allows computers to learn and act like humans do, and improve their learning over time in autonomous fashion, by feeding them data and information in the form of observations and real-world interactions." ;
rdfs:subClassOf obo:IAO_0000064 .
obo:IAO_0000033 a rdfs:Class ;
rdfs:label "directive information entity"@en ;
rdfs:comment "An information content entity whose concretizations indicate to their bearer how to realize them in a process."@en ;
rdfs:subClassOf obo:IAO_0000030 .
a rdfs:Class ;
rdfs:label "Knowledge representation"@en ;
rdfs:comment "A knowledge representation role is a role borne by a data format which utilizes formalisms to make complex systems easier to design and build. Knowledge representation is the field of artificial intelligence devoted to representing information about the world in a form that a computer system can utilize to solve complex tasks." ;
rdfs:subClassOf obo:BFO_0000023 .
obo:GO_0006006 a rdfs:Class ;
rdfs:label "glucose metabolic process" ;
rdfs:comment "The chemical reactions and pathways involving glucose, the aldohexose gluco-hexose. D-glucose is dextrorotatory and is sometimes known as dextrose; it is an important source of energy for living organisms and is found free as well as combined in homo- and hetero-oligosaccharides and polysaccharides." ;
rdfs:subClassOf obo:GO_0005996 .
obo:UBERON_0006925 a rdfs:Class ;
rdfs:label "digestive system gland" ;
rdfs:comment "Any gland that is part of the digestive system." ;
rdfs:subClassOf obo:UBERON_0002530 .
obo:BFO_0000002 a rdfs:Class ;
rdfs:label "continuant" ;
rdfs:comment "An entity that exists in full at any time in which it exists at all, persists through time while maintaining its identity and has no temporal parts."@en ;
rdfs:subClassOf obo:BFO_0000001 .
obo:NCIT_C13426 a rdfs:Class ;
rdfs:label "Protein Binding Domain" ;
rdfs:comment "Protein Binding Domains are structural motifs responsible for the peptide/protein binding activity of proteins." ;
rdfs:subClassOf obo:SO_0000409 .
a rdfs:Class ;
rdfs:label "Clustering" ;
rdfs:comment "Group together some data entities on the basis of similarities such that entities in the same group (cluster) are more similar to each other than to those in other groups (clusters)." ;
rdfs:subClassOf .
a rdfs:Class ;
rdfs:label "Network analysis" ;
rdfs:comment "Generate, process or analyse a biological network." ;
rdfs:subClassOf .
obo:SO_0000312 a rdfs:Class ;
rdfs:label "experimentally_determined" ;
rdfs:comment "Attribute to describe a feature that has been experimentally verified." ;
rdfs:subClassOf obo:SO_0000733 .
obo:CHEBI_36357 a rdfs:Class ;
rdfs:label "polyatomic entity" ;
rdfs:comment "Any molecular entity consisting of more than one atom." ;
rdfs:subClassOf obo:CHEBI_23367 .
obo:OBCS_0000049 a rdfs:Class ;
rdfs:label "accuracy" ;
rdfs:comment "A data item that refers to the number of true positives and true negatives divided by the total number of observations." ;
rdfs:subClassOf obo:OBCS_0000220 .
obo:OBI_0000181 a rdfs:Class ;
rdfs:label "population" ;
rdfs:comment "A population is a group of material entities consisting of individuals which share a particular characteristic such as inhabiting a particular region or area or ability to interbreed." ;
rdfs:subClassOf obo:BFO_0000040 .
obo:OBI_0000953 a rdfs:Class ;
rdfs:label "processed specimen" ;
rdfs:comment "A specimen that has been intentionally physically modified."@en ;
rdfs:subClassOf obo:OBI_0000047 , obo:OBI_0100051 .
obo:GO_0043226 a rdfs:Class ;
rdfs:label "organelle" ;
rdfs:comment "Organized structure of distinctive morphology and function. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton, and prokaryotic structures such as anammoxosomes and pirellulosomes. Excludes the plasma membrane." ;
rdfs:subClassOf obo:GO_0110165 .
a rdfs:Class ;
rdfs:label "dissociation constant" ;
rdfs:comment "Synonym: Kd " ;
rdfs:subClassOf .
obo:GO_0016043 a rdfs:Class ;
rdfs:label "cellular component organization" ;
rdfs:comment "A process that results in the assembly, arrangement of constituent parts, or disassembly of a cellular component." ;
rdfs:subClassOf obo:GO_0009987 .
obo:SO_0000655 a rdfs:Class ;
rdfs:label "ncRNA" ;
rdfs:comment "An RNA transcript that does not encode for a protein rather the RNA molecule is the gene product." ;
rdfs:subClassOf obo:SO_0000233 .
obo:PATO_0000058 a rdfs:Class ;
rdfs:label "odor" ;
rdfs:comment "A physical quality inhering in a bearer by virtue of the bearer's molecules being are aerially dispersed and perceived by an odorant receptor." ;
rdfs:subClassOf obo:PATO_0001018 .
obo:GO_0140013 a rdfs:Class ;
rdfs:label "meiotic nuclear division" ;
rdfs:comment "One of the two nuclear divisions that occur as part of the meiotic cell cycle." ;
rdfs:subClassOf obo:GO_0016043 , obo:GO_1903046 .
obo:IAO_0000064 a rdfs:Class ;
rdfs:label "algorithm"@en ;
rdfs:comment "A plan specification which describes the inputs and output of mathematical functions as well as workflow of execution for achieving an predefined objective. Algorithms are realized usually by means of implementation as computer programs for execution by automata."@en ;
rdfs:subClassOf obo:IAO_0000104 .
a rdfs:Class ;
rdfs:label "Protein identification" ;
rdfs:comment "Identification of protein, for example from one or more peptide identifications by tandem mass spectrometry." ;
rdfs:subClassOf , .
obo:SO_0001059 a rdfs:Class ;
rdfs:label "sequence_alteration" ;
rdfs:comment "A sequence_alteration is a sequence_feature whose extent is the deviation from another sequence." ;
rdfs:subClassOf obo:SO_0000110 .
obo:GO_0005813 a rdfs:Class ;
rdfs:label "centrosome" ;
rdfs:comment "A structure comprised of a core structure (in most organisms, a pair of centrioles) and peripheral material from which a microtubule-based structure, such as a spindle apparatus, is organized. Centrosomes occur close to the nucleus during interphase in many eukaryotic cells, though in animal cells it changes continually during the cell-division cycle." ;
rdfs:subClassOf obo:GO_0110165 .
obo:GO_0090304 a rdfs:Class ;
rdfs:label "nucleic acid metabolic process" ;
rdfs:comment "Any cellular metabolic process involving nucleic acids." ;
rdfs:subClassOf obo:GO_0043170 , obo:GO_0044238 .
obo:CHEBI_51143 a rdfs:Class ;
rdfs:label "nitrogen molecular entity" ;
rdfs:subClassOf obo:CHEBI_33302 .
obo:GO_1903561 a rdfs:Class ;
rdfs:label "extracellular vesicle" ;
rdfs:comment "Any vesicle that is part of the extracellular region." ;
rdfs:subClassOf obo:GO_0031982 , obo:GO_0065010 .
obo:SO_0000839 a rdfs:Class ;
rdfs:label "polypeptide_region" ;
rdfs:comment "Biological sequence region that can be assigned to a specific subsequence of a polypeptide." ;
rdfs:subClassOf obo:SO_0001411 .
a rdfs:Class ;
rdfs:label "exposure" ;
rdfs:comment "The act of subjecting someone or something to an influencing experience. E.g. exposure to cigarette smoke" ;
rdfs:subClassOf .
obo:UBERON_0000061 a rdfs:Class ;
rdfs:label "anatomical structure" ;
rdfs:comment "Material anatomical entity that is a single connected structure with inherent 3D shape generated by coordinated expression of the organism's own genome." ;
rdfs:subClassOf obo:UBERON_0000465 .
obo:DOID_409 a rdfs:Class ;
rdfs:label "liver disease"@en ;
rdfs:subClassOf obo:DOID_7 .
obo:CHEBI_33675 a rdfs:Class ;
rdfs:label "p-block molecular entity" ;
rdfs:comment "A main group molecular entity that contains one or more atoms of a p-block element." ;
rdfs:subClassOf obo:CHEBI_33579 .
obo:GO_0019222 a rdfs:Class ;
rdfs:label "regulation of metabolic process" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways within a cell or an organism." ;
rdfs:subClassOf obo:GO_0050794 .
obo:GO_0023052 a rdfs:Class ;
rdfs:label "signaling" ;
rdfs:comment "The entirety of a process in which information is transmitted within a biological system. This process begins with an active signal and ends when a cellular response has been triggered." ;
rdfs:subClassOf obo:GO_0050789 .
obo:SO_0005836 a rdfs:Class ;
rdfs:label "regulatory_region" ;
rdfs:comment "A region of sequence that is involved in the control of a biological process." ;
rdfs:subClassOf obo:SO_0000831 .
obo:CHEBI_24835 a rdfs:Class ;
rdfs:label "inorganic molecular entity" ;
rdfs:comment "A molecular entity that contains no carbon." ;
rdfs:subClassOf obo:CHEBI_23367 .
a rdfs:Class ;
rdfs:label "PCR primers" ;
rdfs:comment "Oligonucleotide primer(s) for PCR and DNA amplification, for example a minimal primer set." ;
rdfs:subClassOf obo:SO_0001260 .
a rdfs:Class ;
rdfs:label "Operation" ;
rdfs:comment "A function that processes a set of inputs and results in a set of outputs, or associates arguments (inputs) with values (outputs)." ;
rdfs:subClassOf obo:OBI_0200000 .
obo:CHEBI_33259 a rdfs:Class ;
rdfs:label "elemental molecular entity" ;
rdfs:comment "A molecular entity all atoms of which have the same atomic number." ;
rdfs:subClassOf obo:CHEBI_23367 .
obo:CHEBI_78298 a rdfs:Class ;
rdfs:label "environmental contaminant" ;
rdfs:comment "Any minor or unwanted substance introduced into the environment that can have undesired effects." ;
rdfs:subClassOf obo:CHEBI_51086 .
obo:NCIT_C104154 a rdfs:Class ;
rdfs:label "Circulating Cell-Free RNA" ;
rdfs:comment "RNA found in blood plasma and other bodily fluids that is not associated with cells." ;
rdfs:subClassOf obo:CHEBI_33697 .
obo:CHEBI_37734 a rdfs:Class ;
rdfs:label "phosphoric ester" ;
rdfs:subClassOf obo:CHEBI_26079 , obo:CHEBI_36963 .
obo:GO_0007608 a rdfs:Class ;
rdfs:label "sensory perception of smell" ;
rdfs:comment "The series of events required for an organism to receive an olfactory stimulus, convert it to a molecular signal, and recognize and characterize the signal. Olfaction involves the detection of chemical composition of an organism's ambient medium by chemoreceptors. This is a neurological process." ;
rdfs:subClassOf obo:GO_0007606 .
obo:SO_0000243 a rdfs:Class ;
rdfs:label "internal_ribosome_entry_site" ;
rdfs:comment "Sequence element that recruits a ribosomal subunit to internal mRNA for translation initiation." ;
rdfs:subClassOf obo:SO_0000836 .
obo:NCIT_C142529 a rdfs:Class ;
rdfs:label "Electronic Health Record" ;
rdfs:comment "A digital version of a patient's medical history." ;
rdfs:subClassOf obo:OGMS_0000123 .
obo:OGMS_0000031 a rdfs:Class ;
rdfs:label "disease" ;
rdfs:comment "A disposition (i) to undergo pathological processes that (ii) exists in an organism because of one or more disorders in that organism."@en ;
rdfs:subClassOf obo:BFO_0000016 .
obo:OBI_0000185 a rdfs:Class ;
rdfs:label "imaging assay" ;
rdfs:comment "An imaging assay is an assay to produce a picture of an entity." ;
rdfs:subClassOf obo:OBI_0000070 .
obo:SO_0000188 a rdfs:Class ;
rdfs:label "intron" ;
rdfs:comment "A region of a primary transcript that is transcribed, but removed from within the transcript by splicing together the sequences (exons) on either side of it." ;
rdfs:subClassOf obo:SO_0000835 .
obo:CHEBI_16670 a rdfs:Class ;
rdfs:label "peptide" ;
rdfs:comment "Amide derived from two or more amino carboxylic acid molecules (the same or different) by formation of a covalent bond from the carbonyl carbon of one to the nitrogen atom of another with formal loss of water. The term is usually applied to structures formed from alpha-amino acids, but it includes those derived from any amino carboxylic acid. X = OH, OR, NH2, NHR, etc." ;
rdfs:subClassOf obo:CHEBI_37622 , obo:CHEBI_50047 .
obo:CL_0000578 a rdfs:Class ;
rdfs:label "experimentally modified cell in vitro" ;
rdfs:subClassOf obo:CL_0001034 .
obo:CHEBI_18111 a rdfs:Class ;
rdfs:label "ribosomal RNA" ;
rdfs:comment "RNA molecules which are essential structural and functional components of ribosomes, the subcellular units responsible for protein synthesis." ;
rdfs:subClassOf obo:CHEBI_33697 .
obo:SO_0001037 a rdfs:Class ;
rdfs:label "mobile_genetic_element" ;
rdfs:comment "A nucleotide region with either intra-genome or intracellular mobility, of varying length, which often carry the information necessary for transfer and recombination with the host genome." ;
rdfs:subClassOf obo:SO_0001411 .
obo:STATO_0000235 a rdfs:Class ;
rdfs:label "genetic association study"@en ;
rdfs:comment "A genetic association study is a kind of study whose objective is to detect associations between phenotypes, between a phenotype and a genetic polymorphism or between two genetic polymorphisms."@en ;
rdfs:subClassOf obo:OBI_0000066 .
obo:OBI_0100026 a rdfs:Class ;
rdfs:label "organism"@en ;
rdfs:comment "A material entity that is an individual living system, such as animal, plant, bacteria or virus, that is capable of replicating or reproducing, growth and maintenance in the right environment. An organism may be unicellular or made up, like humans, of many billions of cells divided into specialized tissues and organs."@en ;
rdfs:subClassOf obo:BFO_0000040 .
obo:GO_0030431 a rdfs:Class ;
rdfs:label "sleep" ;
rdfs:comment "Any process in which an organism enters and maintains a periodic, readily reversible state of reduced awareness and metabolic activity. Usually accompanied by physical relaxation, the onset of sleep in humans and other mammals is marked by a change in the electrical activity of the brain." ;
rdfs:subClassOf obo:GO_0032501 .
a rdfs:Class ;
rdfs:label "Chemical structure image" ;
rdfs:comment "An image of the structure of a small chemical compound." ;
rdfs:subClassOf obo:IAO_0000101 .
obo:SO_0000858 a rdfs:Class ;
rdfs:label "orthologous" ;
rdfs:comment "An attribute describing a kind of homology where divergence occurred after a speciation event." ;
rdfs:subClassOf obo:SO_0000857 .
obo:CHMO_0001112 a rdfs:Class ;
rdfs:label "super-resolution bright-field microscopy" ;
rdfs:comment "Microscopy where the specimen is illuminated with light transmitted from a source on the opposite side of the specimen from the objective, and image resolution (which is normally limited by diffraction) is enhanced by processing the images with image restoration algorithms." ;
rdfs:subClassOf obo:CHMO_0000104 .
a rdfs:Class ;
rdfs:label "Transmembrane protein prediction" ;
rdfs:comment "Predict and/or classify transmembrane proteins or transmembrane (helical) domains or regions in protein sequences." ;
rdfs:subClassOf .
obo:UBERON_0004121 a rdfs:Class ;
rdfs:label "ectoderm-derived structure" ;
rdfs:comment "An anatomical structure that develops (entirely or partially) from the ectoderm." ;
rdfs:subClassOf obo:UBERON_0000061 .
obo:OMIT_0009360 a rdfs:Class ;
rdfs:label "Major Histocompatibility Complex" ;
rdfs:subClassOf obo:GO_0032991 .
obo:CHEBI_15339 a rdfs:Class ;
rdfs:label "acceptor" ;
rdfs:comment "A molecular entity that can accept an electron, a pair of electrons, an atom or a group from another molecular entity." ;
rdfs:subClassOf obo:CHEBI_51086 .
obo:CHEBI_17891 a rdfs:Class ;
rdfs:label "donor" ;
rdfs:comment "A molecular entity that can transfer (\"donate\") an electron, a pair of electrons, an atom or a group to another molecular entity." ;
rdfs:subClassOf obo:CHEBI_51086 .
obo:NCIT_C49667 a rdfs:Class ;
rdfs:label "Safety Study" ;
rdfs:comment "A study of the relative safety of treatment of a disease. Usually this is a Phase I or II trial." ;
rdfs:subClassOf obo:OBI_0000066 .
obo:STATO_0000184 a rdfs:Class ;
rdfs:label "ratio" ;
rdfs:comment "A ratio is a data item which is formed with two numbers r and s is written r/s, where r is the numerator and s is the denominator. The ratio of r to s is equivalent to the quotient r/s."@en ;
rdfs:subClassOf obo:STATO_0000039 .
obo:MI_2231 a rdfs:Class ;
rdfs:label "coexpression" ;
rdfs:comment "This approach infers interacting pairs of proteins looking at expression data coming from transcript expression datasets. Co-expressed pairs of genes are ranked and predicted to be interacting proteins as well." ;
rdfs:subClassOf obo:OBI_0200000 .
obo:OBI_1110201 a rdfs:Class ;
rdfs:label "allergen" ;
rdfs:comment "A material entity bearing the disposition to cause an allergic reaction"@en ;
rdfs:subClassOf obo:BFO_0000040 .
obo:PR_000000001 a rdfs:Class ;
rdfs:label "protein" ;
rdfs:comment "An amino acid chain that is canonically produced de novo by ribosome-mediated translation of a genetically-encoded mRNA, and any derivatives thereof." ;
rdfs:subClassOf obo:CHEBI_25367 .
obo:CHEBI_33708 a rdfs:Class ;
rdfs:label "amino-acid residue" ;
rdfs:comment "When two or more amino acids combine to form a peptide, the elements of water are removed, and what remains of each amino acid is called an amino-acid residue." ;
rdfs:subClassOf obo:CHEBI_24431 .
obo:IAO_0000101 a rdfs:Class ;
rdfs:label "image"@en ;
rdfs:comment "An image is an affine projection to a two dimensional surface, of measurements of some quality of an entity or entities repeated at regular intervals across a spatial range, where the measurements are represented as color and luminosity on the projected on surface."@en ;
rdfs:subClassOf obo:IAO_0000308 .
a rdfs:Class ;
rdfs:label "GO-term enrichment data" ;
rdfs:comment "A ranked list of Gene Ontology concepts, each associated with a p-value, concerning or derived from the analysis of e.g. a set of genes or proteins." ;
rdfs:subClassOf obo:IAO_0000027 .
obo:SO_1000035 a rdfs:Class ;
rdfs:label "duplication" ;
rdfs:comment "An insertion which derives from, or is identical in sequence to, nucleotides present at a known location in the genome." ;
rdfs:subClassOf obo:SO_0000667 .
obo:PATO_0002146 a rdfs:Class ;
rdfs:label "virulence" ;
rdfs:comment "A quality inhering in a bearer by virtue of the severity of infectious disease caused by the bearer in a target organism." ;
rdfs:subClassOf obo:PATO_0001995 .
obo:SO_0001877 a rdfs:Class ;
rdfs:label "lncRNA" ;
rdfs:comment "A non-coding RNA generally longer than 200 nucleotides that cannot be classified as any other ncRNA subtype. Similar to mRNAs, lncRNAs are mainly transcribed by RNA polymerase II, are often capped by 7-methyl guanosine at their 5' ends, polyadenylated at their 3' ends and may be spliced." ;
rdfs:subClassOf obo:SO_0000655 .
obo:CHMO_0001806 a rdfs:Class ;
rdfs:label "nuclear magnetic resonance method" ;
rdfs:comment "A technique or procedure applied in nuclear magnetic resonance experiments." ;
rdfs:subClassOf obo:CHMO_0001215 .
obo:NCIT_C16809 a rdfs:Class ;
rdfs:label "Magnetic Resonance Imaging" ;
rdfs:comment "Imaging that uses radiofrequency waves and a strong magnetic field rather than x-rays to provide detailed pictures of internal organs and tissues. The technique is valuable for the diagnosis of many pathologic conditions, including cancer, heart and vascular disease, stroke, and joint and musculoskeletal disorders." ;
rdfs:subClassOf .
obo:CHEBI_37622 a rdfs:Class ;
rdfs:label "carboxamide" ;
rdfs:comment "An amide of a carboxylic acid, having the structure RC(=O)NR2. The term is used as a suffix in systematic name formation to denote the -C(=O)NH2 group including its carbon atom." ;
rdfs:subClassOf obo:CHEBI_35352 , obo:CHEBI_36963 .
obo:GO_0000775 a rdfs:Class ;
rdfs:label "chromosome, centromeric region" ;
rdfs:comment "The region of a chromosome that includes the centromeric DNA and associated proteins. In monocentric chromosomes, this region corresponds to a single area of the chromosome, whereas in holocentric chromosomes, it is evenly distributed along the chromosome." ;
rdfs:subClassOf obo:GO_0098687 .
obo:PATO_0000043 a rdfs:Class ;
rdfs:label "flavor" ;
rdfs:comment "A quality of a physical entity inhering in a bearer by virtue of whether the bearer's molecules are being perceived by a taste and odorant receptors." ;
rdfs:subClassOf obo:PATO_0001018 .
obo:SO_0001021 a rdfs:Class ;
rdfs:label "chromosome_breakpoint" ;
rdfs:comment "A chromosomal region that may sustain a double-strand break, resulting in a recombination event." ;
rdfs:subClassOf obo:SO_0000110 .
obo:BFO_0000019 a rdfs:Class ;
rdfs:label "quality"@en ;
rdfs:subClassOf obo:BFO_0000020 .
obo:GO_0009889 a rdfs:Class ;
rdfs:label "regulation of biosynthetic process" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of substances." ;
rdfs:subClassOf obo:GO_0019222 .
obo:OBI_0000115 a rdfs:Class ;
rdfs:label "intervention design" ;
rdfs:comment "An intervention design is a study design in which a controlled process applied to the subjects (the intervention) serves as the independent variable manipulated by the experimentalist. The treatment (perturbation or intervention) defined can be defined as a combination of values taken by independent variable manipulated by the experimentalists are applied to the recruited subjects assigned (possibly by applying specific methods) to treatment groups. The specificity of intervention design is the fact that independent variables are being manipulated and a response of the biological system is evaluated via response variables as monitored by possibly a series of assays."@en ;
rdfs:subClassOf obo:OBI_0500000 .
obo:SO_0000167 a rdfs:Class ;
rdfs:label "promoter" ;
rdfs:comment "A regulatory_region composed of the TSS(s) and binding sites for TF_complexes of the core transcription machinery. A region (DNA) to which RNA polymerase binds, to begin transcription." ;
rdfs:subClassOf obo:SO_0005836 .
obo:OBI_0002176 a rdfs:Class ;
rdfs:label "electrophysiology assay" ;
rdfs:comment "An assay that measures the electrical properties of biological cells or tissues. Typically, this assay will generate measurements of voltage changes or electric current (or other associated variables such as impedence or capacitance)."@en ;
rdfs:subClassOf obo:OBI_0000070 .
a rdfs:Class ;
rdfs:label "infectious disease" ;
rdfs:comment "A disorder directly resulting from the presence and activity of a microbial, viral, or parasitic agent in humans. It can be transmitted by direct or indirect contact." ;
rdfs:subClassOf obo:OGMS_0000031 .
obo:OBCS_0000233 a rdfs:Class ;
rdfs:label "transformed data item"@en ;
rdfs:comment "A data item that is produced as the output of a data transformation." ;
rdfs:subClassOf obo:IAO_0000027 .
a rdfs:Class ;
rdfs:label "toxicity"@en ;
rdfs:subClassOf obo:PATO_0001018 .
a rdfs:Class ;
rdfs:label "Name" ;
rdfs:comment "A name of a thing, which need not necessarily uniquely identify it." ;
rdfs:subClassOf obo:IAO_0020000 .
a rdfs:Class ;
rdfs:label "Nucleic acid design" ;
rdfs:comment "Design (or predict) nucleic acid sequences with specific chemical or physical properties." ;
rdfs:subClassOf .
a rdfs:Class ;
rdfs:label "Protein feature detection" ;
rdfs:comment "Predict, recognise and identify positional features in proteins from analysing protein sequences or structures." ;
rdfs:subClassOf , .
obo:SO_0000239 a rdfs:Class ;
rdfs:label "flanking_region" ;
rdfs:comment "The sequences extending on either side of a specific region." ;
rdfs:subClassOf obo:SO_0000001 .
obo:PO_0007033 a rdfs:Class ;
rdfs:label "whole plant development stage" ;
rdfs:comment "A plant structure development stage (PO:0009012) that has as primary participant a whole plant (PO:0000003)." ;
rdfs:subClassOf obo:UBERON_0000105 .
obo:CL_0000084 a rdfs:Class ;
rdfs:label "T cell" ;
rdfs:comment "A type of lymphocyte whose defining characteristic is the expression of a T cell receptor complex." ;
rdfs:subClassOf obo:CL_0000542 .
a rdfs:Class ;
rdfs:label "Protein structure" ;
rdfs:comment "3D coordinate and associated data for a protein tertiary (3D) structure, or part of a structure, possibly in complex with other molecules." ;
rdfs:subClassOf .
a rdfs:Class ;
rdfs:label "Sequence annotation" ;
rdfs:comment "Annotate a molecular sequence record with terms from a controlled vocabulary." ;
rdfs:subClassOf .
obo:GO_0009987 a rdfs:Class ;
rdfs:label "cellular process" ;
rdfs:comment "Any process that is carried out at the cellular level, but not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level." ;
rdfs:subClassOf obo:GO_0008150 .
obo:MI_0074 a rdfs:Class ;
rdfs:label "mutation analysis" ;
rdfs:comment "Mutant molecules are produced by random or directed techniques and assayed for their ability to support binding." ;
rdfs:subClassOf obo:OBI_0000070 .
a rdfs:Class ;
rdfs:label "Chemical formula" ;
rdfs:comment "A specification of a chemical structure." ;
rdfs:subClassOf .
obo:OBI_1110108 a rdfs:Class ;
rdfs:label "material to be added" ;
rdfs:comment "A material entity that is added to another material entity in an “adding a material entity into a target” process."@en ;
rdfs:subClassOf obo:BFO_0000040 .
obo:CLO_0036932 a rdfs:Class ;
rdfs:label "Hybridoma" ;
rdfs:subClassOf .
obo:GO_0051179 a rdfs:Class ;
rdfs:label "localization" ;
rdfs:comment "Any process in which a cell, a substance, or a cellular entity, such as a protein complex or organelle, is transported, tethered to or otherwise maintained in a specific location. In the case of substances, localization may also be achieved via selective degradation." ;
rdfs:subClassOf obo:GO_0008150 .
a rdfs:Class ;
rdfs:label "Reaction data" ;
rdfs:comment "Data concerning a biochemical reaction, typically data and more general annotation on the kinetics of enzyme-catalysed reaction." ;
rdfs:subClassOf obo:IAO_0000027 .
obo:GO_0043232 a rdfs:Class ;
rdfs:label "intracellular membraneless organelle" ;
rdfs:comment "Organized structure of distinctive morphology and function, not bounded by a lipid bilayer membrane and occurring within the cell. Includes ribosomes, the cytoskeleton and chromosomes." ;
rdfs:subClassOf obo:GO_0043229 .
a rdfs:Class ;
rdfs:label "Identifier (by type of entity)" ;
rdfs:comment "An identifier that identifies a particular type of data." ;
rdfs:subClassOf obo:IAO_0020000 .
obo:GO_0006473 a rdfs:Class ;
rdfs:label "protein acetylation" ;
rdfs:comment "The addition of an acetyl group to a protein amino acid. An acetyl group is CH3CO-, derived from acetic [ethanoic] acid." ;
rdfs:subClassOf obo:GO_0036211 .
obo:OAE_0000094 a rdfs:Class ;
rdfs:label "therapeutic intervention" ;
rdfs:comment "a medical intervention that is used for therapeutic purpose" ;
rdfs:subClassOf obo:OAE_0000002 .
obo:OMIT_0028181 a rdfs:Class ;
rdfs:label "Crowdsourcing" ;
rdfs:subClassOf .
obo:CHEBI_25703 a rdfs:Class ;
rdfs:label "organic phosphate" ;
rdfs:subClassOf obo:CHEBI_25710 , obo:CHEBI_26079 .
obo:FBcv_0000155 a rdfs:Class ;
rdfs:label "single balancer" ;
rdfs:comment "Chromosome that carries inversions and visible mutations, and which can be used to identify the genotype of an individual." ;
rdfs:subClassOf obo:CHEBI_24432 .
a rdfs:Class ;
rdfs:label "Protein sequence analysis" ;
rdfs:comment "Analyse a protein sequence (using methods that are only applicable to protein sequences)." ;
rdfs:subClassOf .
a rdfs:Class ;
rdfs:label "vaccination" ;
rdfs:comment "A process that involves adding vaccine into a host (e.g., human, mouse) in vivo with the intent to invoke a protective immune response." ;
rdfs:subClassOf obo:OBI_0000011 .
a rdfs:Class ;
rdfs:label "Sequence composition, complexity and repeats" ;
rdfs:comment "The archival, processing and analysis of the basic character composition of molecular sequences, for example character or word frequency, ambiguity, complexity, particularly regions of low complexity, and repeats or the repetitive nature of molecular sequences." ;
rdfs:subClassOf obo:SO_0000400 .
a rdfs:Class ;
rdfs:label "web service" ;
rdfs:comment "A web service is a software interface which works as a method of communication between two electronic devices over the World Wide Web and which is provided at a particular network address. There are two major classes of Web services: REST-compliant Web services, and arbitrary (or application-specific) Web services." ;
rdfs:subClassOf obo:IAO_0000030 .
obo:OBI_0001632 a rdfs:Class ;
rdfs:label "immuno staining assay" ;
rdfs:comment "A assay detecting a molecular label assay in which the label is attached to an antibody so that substances are marked based on the antibody's binding specificity."@en ;
rdfs:subClassOf obo:OBI_0600017 .
obo:NCIT_C13302 a rdfs:Class ;
rdfs:label "Secondary Protein Structure" ;
rdfs:comment "The specific 3-dimensional folded protein structure that is determined by the hydrogen bonds formed between amino acids in the polypeptide chain." ;
rdfs:subClassOf .
a rdfs:Class ;
rdfs:label "copy number variation" ;
rdfs:comment "A quantification of a genomic variation that increases or decreases the copy number of a given region." ;
rdfs:subClassOf .
obo:NCIT_C61256 a rdfs:Class ;
rdfs:label "Monitoring" ;
rdfs:comment "The act of observing something (and sometimes keeping a record of it)." ;
rdfs:subClassOf obo:OBI_0000070 .
obo:CHMO_0000800 a rdfs:Class ;
rdfs:label "spectrum" ;
rdfs:comment "A plot of a measured quantity against some experimental parameter." ;
rdfs:subClassOf obo:CHMO_0000793 .
obo:OBI_0302900 a rdfs:Class ;
rdfs:label "group randomization"@en ;
rdfs:comment "A group assignment which relies on chance to assign materials to a group of materials in order to avoid bias in experimental set up."@en ;
rdfs:subClassOf obo:OBI_0600015 .
obo:MS_1001193 a rdfs:Class ;
rdfs:label "confidence score" ;
rdfs:comment "Result of quality estimation: confidence score." ;
rdfs:subClassOf obo:IAO_0000027 .
obo:NCIT_C17958 a rdfs:Class ;
rdfs:label "Functional Magnetic Resonance Imaging" ;
rdfs:comment "The principle of functional MRI imaging is to take a series of images of an organ in quick succession and to statistically analyze the images for differences among them. Most commonly used in studies of brain function." ;
rdfs:subClassOf obo:NCIT_C16809 .
obo:SO_0001023 a rdfs:Class ;
rdfs:label "allele" ;
rdfs:comment "An allele is one of a set of coexisting sequence variants of a gene." ;
rdfs:subClassOf obo:SO_0001260 .
obo:GO_0008104 a rdfs:Class ;
rdfs:label "protein localization" ;
rdfs:comment "Any process in which a protein is transported to, or maintained in, a specific location." ;
rdfs:subClassOf obo:GO_0070727 .
obo:CL_0000542 a rdfs:Class ;
rdfs:label "lymphocyte" ;
rdfs:comment "A lymphocyte is a leukocyte commonly found in the blood and lymph that has the characteristics of a large nucleus, a neutral staining cytoplasm, and prominent heterochromatin." ;
rdfs:subClassOf obo:CL_0000842 .
obo:OBI_0302903 a rdfs:Class ;
rdfs:label "nucleic acid hybridization"@en ;
rdfs:comment "a planned process by which totally or partially complementary, single-stranded nucleic acids are combined into a single molecule called heteroduplex or homoduplex to an extent depending on the amount of complementarity."@en ;
rdfs:subClassOf obo:OBI_0000094 .
obo:ENVO_01001691 a rdfs:Class ;
rdfs:label "mass of compounded environmental materials"@en ;
rdfs:comment "An mass of environmental materials which has appreciable quantities of several individual materials, such that the removal of one would convert the mass into a different entity."@en ;
rdfs:subClassOf obo:ENVO_01001686 .
a rdfs:Class ;
rdfs:label "Cytogenetic map" ;
rdfs:comment "A map showing banding patterns derived from direct observation of a stained chromosome." ;
rdfs:subClassOf .
obo:CL_0000325 a rdfs:Class ;
rdfs:label "stuff accumulating cell" ;
rdfs:comment "A cell that is specialised to accumulate a particular substance(s)." ;
rdfs:subClassOf obo:CL_0000000 .
obo:HP_0002664 a rdfs:Class ;
rdfs:label "Neoplasm" ;
rdfs:comment "An organ or organ-system abnormality that consists of uncontrolled autonomous cell-proliferation which can occur in any part of the body as a benign or malignant neoplasm (tumor)." ;
rdfs:subClassOf obo:OGMS_0000023 .
obo:OBI_0000726 a rdfs:Class ;
rdfs:label "peak matching" ;
rdfs:comment "Peak matching is a data transformation performed on a dataset of a graph of ordered data points (e.g. a spectrum) with the objective of pattern matching local maxima above a noise threshold"@en ;
rdfs:subClassOf obo:OBI_0200000 .
obo:GO_0009892 a rdfs:Class ;
rdfs:label "negative regulation of metabolic process" ;
rdfs:comment "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways within a cell or an organism." ;
rdfs:subClassOf obo:GO_0019222 , obo:GO_0048523 .
obo:OBI_0001958 a rdfs:Class ;
rdfs:label "systematic review study design" ;
rdfs:comment "A study design for identifying in the literature prior studies of a pre-determined phenomenon or set of related phenomena according to certain criteria, extracting findings from these studies, and summarizing these findings and/or attempting to draw new conclusions from them which were not justified by any of the individual, prior studies. Many systematic reviews also assess the quality of the studies so reviewed."@en ;
rdfs:subClassOf obo:OBI_0500000 .
obo:CL_0000113 a rdfs:Class ;
rdfs:label "mononuclear phagocyte" ;
rdfs:comment "A vertebrate phagocyte with a single nucleus." ;
rdfs:subClassOf obo:CL_0000518 , obo:CL_0000842 .
obo:SO_0001410 a rdfs:Class ;
rdfs:label "experimental_feature" ;
rdfs:comment "A region which is the result of some arbitrary experimental procedure. The procedure may be carried out with biological material or inside a computer." ;
rdfs:subClassOf obo:SO_0000001 .
obo:CHEBI_33696 a rdfs:Class ;
rdfs:label "nucleic acid" ;
rdfs:comment "A macromolecule made up of nucleotide units and hydrolysable into certain pyrimidine or purine bases (usually adenine, cytosine, guanine, thymine, uracil), D-ribose or 2-deoxy-D-ribose and phosphoric acid." ;
rdfs:subClassOf obo:CHEBI_15986 , obo:CHEBI_33839 .
obo:OBI_0000737 a rdfs:Class ;
rdfs:label "cloning vector" ;
rdfs:comment "A cloning vector is an engineered material that is used as an input material for a recombinant vector cloning process to carry inserted nucleic acids. It contains an origin of replication for a specific destination host organism, encodes for a selectable gene product and contains a cloning site."@en ;
rdfs:subClassOf obo:CHEBI_33696 , obo:OBI_0000047 , obo:OBI_1110108 .
obo:OBI_0600015 a rdfs:Class ;
rdfs:label "group assignment"@en ;
rdfs:comment "group assignment is a process which has an organism as specified input and during which a role is assigned"@en ;
rdfs:subClassOf obo:OBI_0000011 .
obo:SO_0000705 a rdfs:Class ;
rdfs:label "tandem_repeat" ;
rdfs:comment "Two or more adjacent copies of a region (of length greater than 1)." ;
rdfs:subClassOf obo:SO_0000657 .
obo:OBI_0400148 a rdfs:Class ;
rdfs:label "DNA microarray" ;
rdfs:comment "A DNA-microarray is a microarray that is used as a physical 2D immobilisation matrix for DNA sequences. DNA microarray-bound DNA fragments are used as targets for a hybridising probed sample."@en ;
rdfs:subClassOf obo:OBI_0400147 .
obo:OBI_0000066 a rdfs:Class ;
rdfs:label "investigation"@en ;
rdfs:comment "a planned process that consists of parts: planning, study design execution, documentation and which produce conclusion(s)."@en ;
rdfs:subClassOf obo:OBI_0000011 .
obo:OMRSE_00000056 a rdfs:Class ;
rdfs:label "hospital organization"@en ;
rdfs:comment "An organization that is the bearer of a hospital role."@en ;
rdfs:subClassOf obo:OBI_0000245 .
obo:SO_1000002 a rdfs:Class ;
rdfs:label "substitution" ;
rdfs:comment "A sequence alteration where the length of the change in the variant is the same as that of the reference." ;
rdfs:subClassOf obo:SO_0001059 , obo:SO_0001411 .
obo:IAO_0000578 a rdfs:Class ;
rdfs:label "centrally registered identifier"@en ;
rdfs:comment "An information content entity that consists of a CRID symbol and additional information about the CRID registry to which it belongs."@en ;
rdfs:subClassOf obo:IAO_0020000 .
obo:CMO_0001108 a rdfs:Class ;
rdfs:label "disease onset/diagnosis measurement" ;
rdfs:comment "Any measurement which expresses a quantity related to the beginning, early stages or development of a disease, or to the official determination of a disease as the cause of the observed symptom(s)." ;
rdfs:subClassOf obo:CMO_0000000 .
a rdfs:Class ;
rdfs:label "Drug identifier" ;
rdfs:comment "Identifier of a drug." ;
rdfs:subClassOf .
obo:ENVO_00000447 a rdfs:Class ;
rdfs:label "marine biome" ;
rdfs:comment "A marine ecosystem which is in its climactic successional state." ;
rdfs:subClassOf obo:ENVO_00002030 , obo:ENVO_01001788 .
obo:OBI_0001686 a rdfs:Class ;
rdfs:label "in-situ hybridization assay" ;
rdfs:comment "An assay that localizes a specific DNA or RNA sequence within a portion or section of tissue using artificially induced nucleic hybridization."@en ;
rdfs:subClassOf obo:OBI_0000070 .
a rdfs:Class ;
rdfs:label "Drug report" ;
rdfs:comment "A human-readable collection of information about a specific drug." ;
rdfs:subClassOf obo:IAO_0000088 .
obo:CHEBI_35352 a rdfs:Class ;
rdfs:label "organonitrogen compound" ;
rdfs:comment "Any heteroorganic entity containing at least one carbon-nitrogen bond." ;
rdfs:subClassOf obo:CHEBI_33285 , obo:CHEBI_51143 .
obo:T4FS_0000141 a rdfs:Class ;
rdfs:label "data management"@en ;
rdfs:comment "The activities of data policies, data planning, data element standardization, information management control, data synchronization, data sharing, and database development, including practices and projects that acquire, control, protect, deliver and enhance the value of data and information."@en ;
rdfs:subClassOf obo:T4FS_0000353 .
obo:CHEBI_33839 a rdfs:Class ;
rdfs:label "macromolecule" ;
rdfs:comment "A macromolecule is a molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass." ;
rdfs:subClassOf obo:CHEBI_23367 .
a rdfs:Class ;
rdfs:label "Agroecosystem" ;
rdfs:comment "A system where communities of plants, microbes and animals inhabiting farmed land, pastures, grasslands or rangelands, interact with each other and their physical environment." ;
rdfs:subClassOf obo:ENVO_01001110 .
obo:CL_0000034 a rdfs:Class ;
rdfs:label "stem cell" ;
rdfs:comment "A relatively undifferentiated cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized cells." ;
rdfs:subClassOf obo:CL_0000255 , obo:CL_0011115 .
obo:MOD_00693 a rdfs:Class ;
rdfs:label "glycosylated residue" ;
rdfs:comment "A protein modification that effectively replaces a hydrogen atom with an carbohydrate-like group through a glycosidic bond." ;
rdfs:subClassOf obo:GO_0036211 .
obo:BFO_0000020 a rdfs:Class ;
rdfs:label "specifically dependent continuant"@en ;
rdfs:comment "b is a relational specifically dependent continuant = Def. b is a specifically dependent continuant and there are n > 1 independent continuants c1, … cn which are not spatial regions are such that for all 1 i < j n, ci and cj share no common parts, are such that for each 1 i n, b s-depends_on ci at every time t during the course of b’s existence (axiom label in BFO2 Reference: [131-004])"@en ;
rdfs:subClassOf obo:BFO_0000002 .
obo:OBI_0000470 a rdfs:Class ;
rdfs:label "mass spectrometry assay" ;
rdfs:comment "An assay that identifies the amount and type of material entities present in a sample by fragmenting the sample and measuring the mass-to-charge ratio of the resulting particles."@en ;
rdfs:subClassOf obo:OBI_0000070 .
a rdfs:Class ;
rdfs:label "Genome visualisation" ;
rdfs:comment "Visualise, format or render a nucleic acid sequence that is part of (and in context of) a complete genome sequence." ;
rdfs:subClassOf , .
obo:CHEBI_16646 a rdfs:Class ;
rdfs:label "carbohydrate" ;
rdfs:comment "Any member of the class of organooxygen compounds that is a polyhydroxy-aldehyde or -ketone or a lactol resulting from their intramolecular condensation (monosaccharides); substances derived from these by reduction of the carbonyl group (alditols), by oxidation of one or more hydroxy groups to afford the corresponding aldehydes, ketones, or carboxylic acids, or by replacement of one or more hydroxy group(s) by a hydrogen atom; and polymeric products arising by intermolecular acetal formation between two or more such molecules (disaccharides, polysaccharides and oligosaccharides). Carbohydrates contain only carbon, hydrogen and oxygen atoms; prior to any oxidation or reduction, most have the empirical formula Cm(H2O)n. Compounds obtained from carbohydrates by substitution, etc., are known as carbohydrate derivatives and may contain other elements. Cyclitols are generally not regarded as carbohydrates." ;
rdfs:subClassOf obo:CHEBI_78616 .
a rdfs:Class ;
rdfs:label "systems description parameter" ;
rdfs:comment "A value, numerical or symbolic, that defines certain characteristics of systems or system functions, or is necessary in their derivation." ;
rdfs:subClassOf obo:IAO_0000030 .
obo:GO_0035194 a rdfs:Class ;
rdfs:label "regulatory ncRNA-mediated post-transcriptional gene silencing" ;
rdfs:comment "A posttranscriptional gene silencing pathway in which regulatory RNAs elicit silencing of specific target genes, either by mRNA destabilization or inhibition of translation." ;
rdfs:subClassOf obo:GO_0016441 .
a rdfs:Class ;
rdfs:label "Medical imaging" ;
rdfs:comment "The use of imaging techniques for clinical purposes for medical research." ;
rdfs:subClassOf .
obo:UO_0000000 a rdfs:Class ;
rdfs:label "unit" ;
rdfs:subClassOf obo:IAO_0000027 .
obo:OBI_0002117 a rdfs:Class ;
rdfs:label "whole genome sequencing assay" ;
rdfs:comment "A DNA sequencing assay that intends to provide information about the sequence of an entire genome of an organism."@en ;
rdfs:subClassOf obo:OBI_0000626 .
obo:GO_0032940 a rdfs:Class ;
rdfs:label "secretion by cell" ;
rdfs:comment "The controlled release of a substance by a cell." ;
rdfs:subClassOf obo:GO_0140352 .
obo:SO_0000409 a rdfs:Class ;
rdfs:label "binding_site" ;
rdfs:comment "A biological_region of sequence that, in the molecule, interacts selectively and non-covalently with other molecules. A region on the surface of a molecule that may interact with another molecule. When applied to polypeptides: Amino acids involved in binding or interactions. It can also apply to an amino acid bond which is represented by the positions of the two flanking amino acids." ;
rdfs:subClassOf obo:SO_0001411 .
obo:SO_0000182 a rdfs:Class ;
rdfs:label "DNA_transposon" ;
rdfs:comment "A transposon where the mechanism of transposition is via a DNA intermediate." ;
rdfs:subClassOf obo:SO_0000101 .
obo:NCIT_C18469 a rdfs:Class ;
rdfs:label "Protein-Protein Interaction" ;
rdfs:comment "Temporary, non-covalent binding between protein molecules. Protein-protein interactions occur as a result of intermolecular physical forces and spatial complementation between domains or motifs. This interaction can be either homotypic or heterotypic and effect protein structure, conformation, and function." ;
rdfs:subClassOf .
obo:GO_0042101 a rdfs:Class ;
rdfs:label "T cell receptor complex" ;
rdfs:comment "A protein complex that contains a disulfide-linked heterodimer of T cell receptor (TCR) chains, which are members of the immunoglobulin superfamily, and mediates antigen recognition, ultimately resulting in T cell activation. The TCR heterodimer is associated with the CD3 complex, which consists of the nonpolymorphic polypeptides gamma, delta, epsilon, zeta, and, in some cases, eta (an RNA splice variant of zeta) or Fc epsilon chains." ;
rdfs:subClassOf obo:GO_0098802 .
a rdfs:Class ;
rdfs:label "Differential protein expression profiling" ;
rdfs:comment "The analysis, using proteomics techniques, to identify proteins whose encoding genes are differentially expressed under a given experimental setup." ;
rdfs:subClassOf .
obo:FBcv_0003195 a rdfs:Class ;
rdfs:label "CAGE" ;
rdfs:comment "Material that has been selected using Cap Analysis Gene Expression, in which the 7-methylguanosine cap at 5' transcript ends is biotinylated and affinity purified." ;
rdfs:subClassOf obo:OBI_0000070 .
obo:SO_0000673 a rdfs:Class ;
rdfs:label "transcript" ;
rdfs:comment "An RNA synthesized on a DNA or RNA template by an RNA polymerase." ;
rdfs:subClassOf obo:SO_0000831 .
obo:GO_0032991 a rdfs:Class ;
rdfs:label "protein-containing complex" ;
rdfs:comment "A stable assembly of two or more macromolecules, i.e. proteins, nucleic acids, carbohydrates or lipids, in which at least one component is a protein and the constituent parts function together." ;
rdfs:subClassOf obo:GO_0005575 .
a rdfs:Class ;
rdfs:label "Structure alignment (pair)" ;
rdfs:comment "Alignment (superimposition) of exactly two molecular tertiary (3D) structures." ;
rdfs:subClassOf obo:OBI_0002567 .
obo:GO_0043687 a rdfs:Class ;
rdfs:label "post-translational protein modification" ;
rdfs:comment "The process of covalently altering one or more amino acids in a protein after the protein has been completely translated and released from the ribosome." ;
rdfs:subClassOf obo:GO_0036211 .
obo:GO_0006396 a rdfs:Class ;
rdfs:label "RNA processing" ;
rdfs:comment "Any process involved in the conversion of one or more primary RNA transcripts into one or more mature RNA molecules." ;
rdfs:subClassOf obo:GO_0044238 .
obo:GO_0060293 a rdfs:Class ;
rdfs:label "germ plasm" ;
rdfs:comment "Differentiated cytoplasm associated with a pole of an oocyte, egg or early embryo that will be inherited by the cells that will give rise to the germ line." ;
rdfs:subClassOf obo:GO_0110165 .
obo:CHEBI_24636 a rdfs:Class ;
rdfs:label "proton" ;
rdfs:comment "Nuclear particle of charge number +1, spin 1/2 and rest mass of 1.007276470(12) u." ;
rdfs:subClassOf obo:CHEBI_15378 , obo:CHEBI_33253 .
obo:OBI_0000415 a rdfs:Class ;
rdfs:label "polymerase chain reaction"@en ;
rdfs:comment "PCR is the process in which a DNA polymerase is used to amplify a piece of DNA by in vitro enzymatic replication. As PCR progresses, the DNA thus generated is itself used as a template for replication. This sets in motion a chain reaction in which the DNA template is exponentially amplified."@en ;
rdfs:subClassOf obo:OBI_0600058 .
obo:ENVO_01000813 a rdfs:Class ;
rdfs:label "astronomical body part"@en ;
rdfs:comment "A material part of an astronomical body." ;
rdfs:subClassOf obo:BFO_0000040 .
a rdfs:Class ;
rdfs:label "Protein image" ;
rdfs:comment "An image of a protein." ;
rdfs:subClassOf obo:IAO_0000101 .
obo:OBI_0000245 a rdfs:Class ;
rdfs:label "organization"@en ;
rdfs:comment "An entity that can bear roles, has members, and has a set of organization rules. Members of organizations are either organizations themselves or individual people. Members can bear specific organization member roles that are determined in the organization rules. The organization rules also determine how decisions are made on behalf of the organization by the organization members."@en ;
rdfs:subClassOf obo:BFO_0000040 .
obo:GO_0009058 a rdfs:Class ;
rdfs:label "biosynthetic process" ;
rdfs:comment "A cellular process consisting of the biochemical pathways by which a living organism synthesizes chemical substances. This typically represents the energy-requiring part of metabolism in which simpler substances are transformed into more complex ones." ;
rdfs:subClassOf obo:GO_0008152 .
obo:CHEBI_36342 a rdfs:Class ;
rdfs:label "subatomic particle" ;
rdfs:comment "A particle smaller than an atom." ;
rdfs:subClassOf obo:BFO_0000040 .
a rdfs:Class ;
rdfs:label "array design" ;
rdfs:comment "An instrument design which describes the design of the array." ;
rdfs:subClassOf obo:IAO_0000030 .
obo:CL_0000451 a rdfs:Class ;
rdfs:label "dendritic cell" ;
rdfs:comment "A cell of hematopoietic origin, typically resident in particular tissues, specialized in the uptake, processing, and transport of antigens to lymph nodes for the purpose of stimulating an immune response via T cell activation. These cells are lineage negative (CD3-negative, CD19-negative, CD34-negative, and CD56-negative)." ;
rdfs:subClassOf obo:CL_0000113 , obo:CL_0000145 .
obo:MI_0966 a rdfs:Class ;
rdfs:label "ultraviolet-visible spectroscopy" ;
rdfs:comment "Ultraviolet-visible spectroscopy or ultraviolet-visible spectrophotometry (UV-Vis or UV/Vis) involves the spectroscopy of photons in the UV-visible region. This means it uses light in the visible and adjacent (near ultraviolet (UV) and near infrared (NIR)) ranges." ;
rdfs:subClassOf obo:OBI_0000070 .
a rdfs:Class ;
rdfs:label "Binding site prediction" ;
rdfs:comment "Identify or predict catalytic residues, active sites or other ligand-binding sites in protein sequences or structures." ;
rdfs:subClassOf , .
obo:DOID_7 a rdfs:Class ;
rdfs:label "disease of anatomical entity"@en ;
rdfs:comment "A disease that manifests in a defined anatomical structure."@en ;
rdfs:subClassOf obo:OGMS_0000031 .
obo:CHEBI_33833 a rdfs:Class ;
rdfs:label "heteroarene" ;
rdfs:comment "A heterocyclic compound formally derived from an arene by replacement of one or more methine (-C=) and/or vinylene (-CH=CH-) groups by trivalent or divalent heteroatoms, respectively, in such a way as to maintain the continuous pi-electron system characteristic of aromatic systems and a number of out-of-plane pi-electrons corresponding to the Hueckel rule (4n+2)." ;
rdfs:subClassOf obo:CHEBI_24532 , obo:CHEBI_33659 .
a rdfs:Class ;
rdfs:label "Accession" ;
rdfs:comment "A persistent (stable) and unique identifier, typically identifying an object (entry) from a database." ;
rdfs:subClassOf obo:IAO_0020000 .
a rdfs:Class ;
rdfs:label "Physical map" ;
rdfs:comment "A map of DNA (linear or circular) annotated with physical features or landmarks such as restriction sites, cloned DNA fragments, genes or genetic markers, along with the physical distances between them." ;
rdfs:subClassOf .
a rdfs:Class ;
rdfs:label "electrocardiography" ;
rdfs:comment "Recording of the moment-to-moment electromotive forces of the HEART as projected onto various sites on the body's surface, delineated as a scalar function of time. The recording is monitored by a tracing on slow moving chart paper or by observing it on a cardioscope, which is a CATHODE RAY TUBE DISPLAY." ;
rdfs:subClassOf .
obo:CHMO_0001001 a rdfs:Class ;
rdfs:label "column chromatography" ;
rdfs:comment "A chromatography method where the stationary bed is within a tube (of standard length 25 cm). The particles of the solid stationary phase or support coated with a liquid stationary phase may fill the whole inside volume of the tube (packed column) or be concentrated on or along the inside tube wall leaving an open, unrestricted path for the mobile phase in the middle part of the tube (open-tubular column)." ;
rdfs:subClassOf obo:CHMO_0001000 .
obo:OBI_0100060 a rdfs:Class ;
rdfs:label "cultured cell population" ;
rdfs:subClassOf obo:OBI_0000047 .
obo:SO_0000316 a rdfs:Class ;
rdfs:label "CDS" ;
rdfs:comment "A contiguous sequence which begins with, and includes, a start codon and ends with, and includes, a stop codon." ;
rdfs:subClassOf obo:SO_0000836 .
obo:SO_0001483 a rdfs:Class ;
rdfs:label "SNV" ;
rdfs:comment "SNVs are single nucleotide positions in genomic DNA at which different sequence alternatives exist." ;
rdfs:subClassOf obo:SO_1000002 .
obo:GO_0043227 a rdfs:Class ;
rdfs:label "membrane-bounded organelle" ;
rdfs:comment "Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane." ;
rdfs:subClassOf obo:GO_0043226 .
obo:DOID_12849 a rdfs:Class ;
rdfs:label "autistic disorder"@en ;
rdfs:comment "An autism spectrum disorder that is characterized by symptoms across all three symptom domains (communication, social, restricted repetitive interests and behaviors), delayed language development, and symptom onset prior to age 3 years."@en ;
rdfs:subClassOf obo:DOID_0060037 .
obo:DOID_14330 a rdfs:Class ;
rdfs:label "Parkinson's disease"@en ;
rdfs:comment "A synucleinopathy that has_material_basis_in degeneration of the central nervous system that often impairs motor skills, speech, and other functions."@en ;
rdfs:subClassOf obo:DOID_331 .
obo:SO_0000756 a rdfs:Class ;
rdfs:label "cDNA" ;
rdfs:comment "DNA synthesized by reverse transcriptase using RNA as a template." ;
rdfs:subClassOf obo:CHEBI_16991 .
obo:OBI_0002438 a rdfs:Class ;
rdfs:label "nuclear ligation assay" ;
rdfs:comment "An assay that detects the proximity of chromosomal DNA through the use of a ligation reaction in isolated nuclei."@en ;
rdfs:subClassOf obo:OBI_0000070 .
a rdfs:Class ;
rdfs:label "high content screen" ;
rdfs:comment "An image analysis technique combining automated fluorescence microscopy with multi-parameter quantitative image analysis for the large scale study of cells (cellomics)." ;
rdfs:subClassOf .
obo:UBERON_0004907 a rdfs:Class ;
rdfs:label "lower digestive tract" ;
rdfs:comment "The region of the digestive tract extending from the beginning of the intestines to the anus[GO - gut definition]." ;
rdfs:subClassOf obo:UBERON_0010000 .
obo:GO_0070085 a rdfs:Class ;
rdfs:label "glycosylation" ;
rdfs:comment "The covalent attachment and further modification of carbohydrate residues to a substrate molecule." ;
rdfs:subClassOf obo:GO_0008152 .
obo:GO_0050693 a rdfs:Class ;
rdfs:label "LBD domain binding" ;
rdfs:comment "Binding to a protein's ligand binding domain (LBD) domain, found in nuclear receptors. In general, the LBDs consist of three layers comprised of twelve alpha-helices and several beta-strands that are organized around a lipophilic ligand-binding pocket." ;
rdfs:subClassOf obo:GO_0005515 .
a rdfs:Class ;
rdfs:label "Model organisms" ;
rdfs:comment "A specific organism, or group of organisms, used to study a particular aspect of biology." ;
rdfs:subClassOf obo:BFO_0000023 .
obo:DRON_00000025 a rdfs:Class ;
rdfs:label "FDA approved drug role"@en ;
rdfs:comment "A drug role conferred by the United States Food and Drug Administration that permits the production, marketing, sale, prescribing, and consump- tion of its bearer in the United States."@en ;
rdfs:subClassOf .
obo:GO_0005622 a rdfs:Class ;
rdfs:label "intracellular anatomical structure" ;
rdfs:comment "A component of a cell contained within (but not including) the plasma membrane. In eukaryotes it includes the nucleus and cytoplasm." ;
rdfs:subClassOf obo:GO_0110165 .
obo:MP_0003935 a rdfs:Class ;
rdfs:label "abnormal craniofacial development" ;
rdfs:comment "anomaly in the process of forming the face and/or cranium" ;
rdfs:subClassOf obo:MP_0005382 .
obo:CL_0000393 a rdfs:Class ;
rdfs:label "electrically responsive cell" ;
rdfs:comment "A cell whose function is determined by its response to an electric signal." ;
rdfs:subClassOf obo:CL_0000211 .
a rdfs:Class ;
rdfs:label "equilibrium or steady-state characteristic" ;
rdfs:comment "Quantitative parameter that characterises a biochemical equilibrium. " ;
rdfs:subClassOf .
obo:SO_0000836 a rdfs:Class ;
rdfs:label "mRNA_region" ;
rdfs:comment "A region of an mRNA." ;
rdfs:subClassOf obo:SO_0000833 .
obo:CHEBI_23906 a rdfs:Class ;
rdfs:label "monoatomic cation" ;
rdfs:subClassOf obo:CHEBI_24867 , obo:CHEBI_36916 .
obo:OBI_0302914 a rdfs:Class ;
rdfs:label "digital curation"@en ;
rdfs:comment "Digital curation is the process of establishing and developing long term repositories of digital assets for current and future reference by researchers, scientists, and historians, and scholars generally."@en ;
rdfs:subClassOf obo:T4FS_0000141 .
a rdfs:Class ;
rdfs:label "Protein domain" ;
rdfs:comment "3D coordinate and associated data for the tertiary (3D) structure of a protein domain." ;
rdfs:subClassOf .
obo:OMIT_0025926 a rdfs:Class ;
rdfs:label "Genome, Mitochondrial" ;
rdfs:subClassOf obo:SO_0001026 .
obo:CHMO_0000156 a rdfs:Class ;
rdfs:label "X-ray diffraction" ;
rdfs:comment "A method for determining structure by directing a beam of X-rays at the sample and detecting the positions and intensities of the diffracted X-rays as a pattern of spots on a photographic plate." ;
rdfs:subClassOf obo:CHMO_0000141 .
obo:FBcv_0000623 a rdfs:Class ;
rdfs:label "enhancer" ;
rdfs:comment "Genotype g1 is enhancer of genotype g2 if (and only if) the phenotype due to the genotype g1g2 is more severe than the sum of phenotypes due to g1 and g2, where all comparisons are under identical environmental conditions." ;
rdfs:subClassOf obo:CHEBI_24432 .
obo:GO_0016441 a rdfs:Class ;
rdfs:label "post-transcriptional gene silencing" ;
rdfs:comment "The inactivation of gene expression that occurs after transcription." ;
rdfs:subClassOf obo:GO_0010629 .
obo:SO_0000276 a rdfs:Class ;
rdfs:label "miRNA" ;
rdfs:comment "Small, ~22-nt, RNA molecule that is the endogenous transcript of a miRNA gene (or the product of other non coding RNA genes). Micro RNAs are produced from precursor molecules (SO:0001244) that can form local hairpin structures, which ordinarily are processed (usually via the Dicer pathway) such that a single miRNA molecule accumulates from one arm of a hairpin precursor molecule. Micro RNAs may trigger the cleavage of their target molecules or act as translational repressors." ;
rdfs:subClassOf obo:SO_0000370 .
a rdfs:Class ;
rdfs:label "Peptide identification" ;
rdfs:comment "Protein or peptide identifications with evidence supporting the identifications, for example from comparing a peptide mass fingerprint (from mass spectrometry) to a sequence database, or the set of typical spectra one obtains when running a protein through a mass spectrometer." ;
rdfs:subClassOf .
obo:DOID_557 a rdfs:Class ;
rdfs:label "kidney disease"@en ;
rdfs:comment "A urinary system disease that is located_in the kidney."@en ;
rdfs:subClassOf obo:DOID_7 .
obo:GO_0008380 a rdfs:Class ;
rdfs:label "RNA splicing" ;
rdfs:comment "The process of removing sections of the primary RNA transcript to remove sequences not present in the mature form of the RNA and joining the remaining sections to form the mature form of the RNA." ;
rdfs:subClassOf obo:GO_0006396 .
a rdfs:Class ;
rdfs:label "channel" ;
rdfs:comment "A component that allows another component to pass through itself, possibly connecting different compartments." ;
rdfs:subClassOf obo:GO_0032991 .
a rdfs:Class ;
rdfs:label "equilibrium or steady-state constant" ;
rdfs:comment "Constant with the dimension of a powered concentration. It is determined at half-saturation, half-activity etc. " ;
rdfs:subClassOf .
obo:SO_0000324 a rdfs:Class ;
rdfs:label "tag" ;
rdfs:comment "A nucleotide sequence that may be used to identify a larger sequence." ;
rdfs:subClassOf obo:SO_0000696 .
obo:OMIT_0012761 a rdfs:Class ;
rdfs:label "Radiation Effects" ;
rdfs:subClassOf obo:NCIT_C41332 .
obo:SO_0000150 a rdfs:Class ;
rdfs:label "read" ;
rdfs:comment "A sequence obtained from a single sequencing experiment. Typically a read is produced when a base calling program interprets information from a chromatogram trace file produced from a sequencing machine." ;
rdfs:subClassOf obo:SO_0000143 .
obo:OBI_0300311 a rdfs:Class ;
rdfs:label "observation design" ;
rdfs:comment "observation design is a study design in which subjects are monitored in the absence of any active intervention by experimentalists."@en ;
rdfs:subClassOf obo:OBI_0500000 .
obo:DOID_0080001 a rdfs:Class ;
rdfs:label "bone disease"@en ;
rdfs:comment "A connective tissue disease that affects the structure or development of bone or causes an impairment of normal bone function."@en ;
rdfs:subClassOf obo:DOID_7 .
obo:CHMO_0000102 a rdfs:Class ;
rdfs:label "optical microscopy" ;
rdfs:comment "Microscopy where the specimen is illuminated with visible light and a system of lenses is used to produce an image." ;
rdfs:subClassOf obo:CHMO_0000067 .
obo:UBERON_0002107 a rdfs:Class ;
rdfs:label "liver" ;
rdfs:comment "Organ which secretes bile and participates in formation of certain blood proteins.[AAO]" ;
rdfs:subClassOf obo:UBERON_0002365 , obo:UBERON_0005177 , obo:UBERON_0006925 .
obo:CHEBI_18154 a rdfs:Class ;
rdfs:label "polysaccharide" ;
rdfs:comment "A biomacromolecule consisting of large numbers of monosaccharide residues linked glycosidically. This term is commonly used only for those containing more than ten monosaccharide residues." ;
rdfs:subClassOf obo:CHEBI_16646 , obo:CHEBI_33694 .
obo:OGMS_0000023 a rdfs:Class ;
rdfs:label "phenotype" ;
rdfs:comment "A (combination of) quality(ies) of an organism determined by the interaction of its genetic make-up and environment that differentiates specific instances of a species from other instances of the same species."@en ;
rdfs:subClassOf obo:BFO_0000019 .
obo:IAO_0000038 a rdfs:Class ;
rdfs:label "graph"@en ;
rdfs:comment "A diagram that presents one or more tuples of information by mapping those tuples in to a two dimensional space in a non arbitrary way."@en ;
rdfs:subClassOf obo:IAO_0000309 .
obo:GO_0007049 a rdfs:Class ;
rdfs:label "cell cycle" ;
rdfs:comment "The progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events. Canonically, the cell cycle comprises the replication and segregation of genetic material followed by the division of the cell, but in endocycles or syncytial cells nuclear replication or nuclear division may not be followed by cell division." ;
rdfs:subClassOf obo:GO_0009987 .
obo:OBI_0600056 a rdfs:Class ;
rdfs:label "protease cleavage"@en ;
rdfs:comment "protease cleavage is an enzymatic cleavage which relies on enzyme with protease activity to act on proteins and produce polypeptides (protein fragments)."@en ;
rdfs:subClassOf obo:OBI_0000231 .
obo:SO_0000110 a rdfs:Class ;
rdfs:label "sequence_feature" ;
rdfs:comment "Any extent of continuous biological sequence." ;
rdfs:subClassOf obo:IAO_0000030 .
obo:SO_0001505 a rdfs:Class ;
rdfs:label "reference_genome" ;
rdfs:comment "A collection of sequences (often chromosomes) taken as the standard for a given organism and genome assembly." ;
rdfs:subClassOf obo:SO_0001026 .
obo:GO_0005996 a rdfs:Class ;
rdfs:label "monosaccharide metabolic process" ;
rdfs:comment "The chemical reactions and pathways involving monosaccharides, the simplest carbohydrates. They are polyhydric alcohols containing either an aldehyde or a keto group and between three to ten or more carbon atoms. They form the constitutional repeating units of oligo- and polysaccharides." ;
rdfs:subClassOf obo:GO_0044238 .
obo:SO_0000667 a rdfs:Class ;
rdfs:label "insertion" ;
rdfs:comment "The sequence of one or more nucleotides added between two adjacent nucleotides in the sequence." ;
rdfs:subClassOf obo:SO_0001059 , obo:SO_0001411 .
obo:RO_0002577 a rdfs:Class ;
rdfs:label "system" ;
rdfs:comment "A material entity consisting of multiple components that are causally integrated." ;
rdfs:subClassOf obo:BFO_0000040 .
obo:GO_0032259 a rdfs:Class ;
rdfs:label "methylation" ;
rdfs:comment "The process in which a methyl group is covalently attached to a molecule." ;
rdfs:subClassOf obo:GO_0008152 .
obo:GO_0065010 a rdfs:Class ;
rdfs:label "extracellular membrane-bounded organelle" ;
rdfs:comment "Organized structure of distinctive morphology and function, bounded by a lipid bilayer membrane and occurring outside the cell." ;
rdfs:subClassOf obo:GO_0043227 .
a rdfs:Class ;
rdfs:label "Geographic location" ;
rdfs:comment "A report about localisation of the isolaton of biological material e.g. country or coordinates." ;
rdfs:subClassOf obo:IAO_0000088 .
obo:NCIT_C17671 a rdfs:Class ;
rdfs:label "Nuclear Receptor" ;
rdfs:comment "Proteins that regulate transcription via interaction with chromatin and basal transcription machinery at the promoter regions of genes. Nuclear receptors are ligand-dependent transcription factors including steroids, retinoids, vitamin D, unliganded thyroid hormone, and orphan receptors (unknown ligands). Coregulators (coactivators or corepressors) are important in mediating these interactions and thereby modulate positive or negative receptor activity." ;
rdfs:subClassOf obo:NCIT_C17207 , obo:NCIT_C18106 .
obo:OGMS_0000063 a rdfs:Class ;
rdfs:label "disease course" ;
rdfs:comment "The totality of all processes through which a given disease instance is realized."@en ;
rdfs:subClassOf obo:BFO_0000015 .
obo:GO_0051252 a rdfs:Class ;
rdfs:label "regulation of RNA metabolic process" ;
rdfs:comment "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving RNA." ;
rdfs:subClassOf obo:GO_0060255 , obo:GO_0080090 .
obo:PATO_0000068 a rdfs:Class ;
rdfs:label "qualitative" ;
rdfs:comment "A quality of an entity that is descriptive or observational, typically not represented numerically." ;
rdfs:subClassOf obo:BFO_0000019 .
obo:CL_0000211 a rdfs:Class ;
rdfs:label "electrically active cell" ;
rdfs:comment "A cell whose function is determined by the generation or the reception of an electric signal." ;
rdfs:subClassOf obo:CL_0000000 .
obo:UBERON_0000479 a rdfs:Class ;
rdfs:label "tissue" ;
rdfs:comment "Multicellular anatomical structure that consists of many cells of one or a few types, arranged in an extracellular matrix such that their long-range organisation is at least partly a repetition of their short-range organisation." ;
rdfs:subClassOf obo:UBERON_0010000 .
obo:MP_0002555 a rdfs:Class ;
rdfs:label "addiction" ;
rdfs:comment "strong dependence on an addictive compound such as alcohol or narcotics that results in uncontrollable cravings for such compounds" ;
rdfs:subClassOf obo:MP_0000001 .
a rdfs:Class ;
rdfs:label "Sequence similarity" ;
rdfs:comment "Sequence similarity is the similarity (expressed as a percentage) of two molecular sequences calculated from their alignment, a scoring matrix for scoring characters substitutions and penalties for gap insertion and extension." ;
rdfs:subClassOf obo:IAO_0000027 .
a rdfs:Class ;
rdfs:label "Data analysis" ;
rdfs:comment "Apply analytical methods to existing data of a specific type." ;
rdfs:subClassOf .
obo:CHEBI_36962 a rdfs:Class ;
rdfs:label "organochalcogen compound" ;
rdfs:comment "An organochalcogen compound is a compound containing at least one carbon-chalcogen bond." ;
rdfs:subClassOf obo:CHEBI_33285 , obo:CHEBI_33304 .