PREFIX obo:
PREFIX rdf:
PREFIX rdfs:
PREFIX xsd:
obo:MONDO_0700096 a rdfs:Class ;
rdfs:label "human disease" ;
rdfs:subClassOf obo:MONDO_0000001 .
obo:BFO_0000050 a rdf:Property ;
rdfs:label "part of"@en ;
rdfs:comment "a core relation that holds between a part and its whole"@en ;
rdfs:range obo:BFO_0000017 , obo:BFO_0000003 , obo:BFO_0000004 , obo:BFO_0000002 , obo:BFO_0000019 , obo:BFO_0000020 ;
rdfs:subPropertyOf obo:RO_0002131 .
obo:RO_0000056 a rdf:Property ;
rdfs:label "participates in"@en ;
rdfs:comment "a relation between a continuant and a process, in which the continuant is somehow involved in the process"@en ;
rdfs:domain obo:BFO_0000002 ;
rdfs:range obo:BFO_0000003 .
obo:RO_0002506 a rdf:Property ;
rdfs:label "causal relation between entities" ;
rdfs:domain obo:BFO_0000002 ;
rdfs:range obo:BFO_0000002 ;
rdfs:subPropertyOf obo:RO_0002410 .
obo:RO_0002566 a rdf:Property ;
rdfs:label "causally influences" ;
rdfs:comment "The entity or characteristic A is causally upstream of the entity or characteristic B, A having an effect on B. An entity corresponds to any biological type of entity as long as a mass is measurable. A characteristic corresponds to a particular specificity of an entity (e.g., phenotype, shape, size)." ;
rdfs:domain obo:BFO_0000002 ;
rdfs:range obo:BFO_0000002 ;
rdfs:subPropertyOf obo:RO_0002506 .
obo:MONDO_0005269 a rdfs:Class ;
rdfs:label "carotid artery disorder" ;
rdfs:comment "A disease involving the carotid artery segment." ;
rdfs:subClassOf obo:MONDO_0000473 , obo:MONDO_0011057 .
obo:HP_0001939 a rdfs:Class ;
rdfs:label "Abnormality of metabolism/homeostasis" ;
rdfs:subClassOf obo:HP_0000118 .
obo:ECTO_0000006 a rdfs:Class ;
rdfs:label "exposure to ultraviolet radiation" ;
rdfs:comment "A exposure event involving the interaction of an exposure receptor to ultraviolet radiation." ;
rdfs:subClassOf obo:ECTO_0000002 .
obo:BFO_0000062 a rdf:Property ;
rdfs:label "preceded by"@en ;
rdfs:comment "x is preceded by y if and only if the time point at which y ends is before or equivalent to the time point at which x starts. Formally: x preceded by y iff ω(y) <= α(x), where α is a function that maps a process to a start point, and ω is a function that maps a process to an end point."@en ;
rdfs:domain obo:BFO_0000003 ;
rdfs:range obo:BFO_0000003 ;
rdfs:subPropertyOf obo:RO_0002086 .
obo:BFO_0000063 a rdf:Property ;
rdfs:label "precedes"@en ;
rdfs:comment "x precedes y if and only if the time point at which x ends is before or equivalent to the time point at which y starts. Formally: x precedes y iff ω(x) <= α(y), where α is a function that maps a process to a start point, and ω is a function that maps a process to an end point."@en ;
rdfs:domain obo:BFO_0000003 ;
rdfs:range obo:BFO_0000003 ;
rdfs:subPropertyOf obo:RO_0002222 .
obo:RO_0002501 a rdf:Property ;
rdfs:label "causal relation between processes" ;
rdfs:comment "p is causally related to q if and only if p or any part of p and q or any part of q are linked by a chain of events where each event pair is one where the execution of p influences the execution of q. p may be upstream, downstream, part of, or a container of q." ;
rdfs:domain obo:BFO_0000003 ;
rdfs:range obo:BFO_0000003 ;
rdfs:subPropertyOf obo:RO_0002410 .
obo:RO_0000057 a rdf:Property ;
rdfs:label "has participant"@en ;
rdfs:comment "a relation between a process and a continuant, in which the continuant is somehow involved in the process"@en ;
rdfs:domain obo:BFO_0000003 ;
rdfs:range obo:BFO_0000002 .
obo:RO_0019000 a rdf:Property ;
rdfs:label "regulates characteristic" ;
rdfs:comment "A relationship that holds between a process and a characteristic in which process (P) regulates characteristic (C) iff: P results in the existence of C OR affects the intensity or magnitude of C." ;
rdfs:domain obo:BFO_0000015 ;
rdfs:range obo:PATO_0000001 ;
rdfs:subPropertyOf obo:RO_0002410 .
obo:RO_0002233 a rdf:Property ;
rdfs:label "has input"@en ;
rdfs:comment "p has input c iff: p is a process, c is a material entity, c is a participant in p, c is present at the start of p, and the state of c is modified during p." ;
rdfs:domain obo:BFO_0000015 ;
rdfs:range obo:BFO_0000002 ;
rdfs:subPropertyOf obo:RO_0000057 .
obo:RO_0002211 a rdf:Property ;
rdfs:label "regulates"@en ;
rdfs:comment "p regulates q iff p is causally upstream of q, the execution of p is not constant and varies according to specific conditions, and p influences the rate or magnitude of execution of q due to an effect either on some enabler of q or some enabler of a part of q." ;
rdfs:domain obo:BFO_0000015 ;
rdfs:range obo:BFO_0000015 ;
rdfs:subPropertyOf obo:RO_0002411 .
obo:RO_0002018 a rdf:Property ;
rdfs:label "has component process" ;
rdfs:comment "w 'has process component' p if p and w are processes, w 'has part' p and w is such that it can be directly disassembled into into n parts p, p2, p3, ..., pn, where these parts are of similar type." ;
rdfs:domain obo:BFO_0000015 ;
rdfs:range obo:BFO_0000015 ;
rdfs:subPropertyOf obo:RO_0002180 .
obo:RO_0002222 a rdf:Property ;
rdfs:label "temporally related to"@en ;
rdfs:domain obo:BFO_0000003 ;
rdfs:range obo:BFO_0000003 .
obo:RO_0002334 a rdf:Property ;
rdfs:label "regulated by"@en ;
rdfs:comment "inverse of regulates" ;
rdfs:domain obo:BFO_0000015 ;
rdfs:range obo:BFO_0000015 ;
rdfs:subPropertyOf obo:RO_0002427 .
obo:HP_0011842 a rdfs:Class ;
rdfs:label "Abnormal skeletal morphology" ;
rdfs:comment "An abnormality of the form, structure, or size of the skeletal system." ;
rdfs:subClassOf obo:HP_0000924 .
obo:BFO_0000034 a rdfs:Class ;
rdfs:label "function"@en ;
rdfs:subClassOf obo:BFO_0000016 .
obo:RO_0000079 a rdf:Property ;
rdfs:label "function of"@en ;
rdfs:comment "a relation between a function and an independent continuant (the bearer), in which the function specifically depends on the bearer for its existence"@en ;
rdfs:domain obo:BFO_0000034 ;
rdfs:range ;
rdfs:subPropertyOf obo:RO_0000052 .
obo:BFO_0000017 a rdfs:Class ;
rdfs:label "realizable entity"@en ;
rdfs:comment "A specifically dependent continuant that inheres in continuant entities and are not exhibited in full at every time in which it inheres in an entity or group of entities. The exhibition or actualization of a realizable entity is a particular manifestation, functioning or process that occurs under certain circumstances."@en ;
rdfs:subClassOf obo:BFO_0000020 .
obo:MONDO_0002447 a rdfs:Class ;
rdfs:label "endometrial carcinoma" ;
rdfs:comment "A malignant tumor arising from the epithelium that lines the cavity of the uterine body. The vast majority of endometrial carcinomas are adenocarcinomas; squamous cell and adenosquamous carcinomas represent a minority of the cases. Endometrioid adenocarcinoma is the most frequently seen variant of endometrial adenocarcinoma. Uterine bleeding is an initial clinical sign. The prognosis depends on the stage of the tumor, the depth of myometrial wall invasion, and the degree of differentiation." ;
rdfs:subClassOf obo:MONDO_0005213 , obo:MONDO_0011962 .
obo:HP_0000708 a rdfs:Class ;
rdfs:label "Atypical behavior" ;
rdfs:comment "Atypical behavior is an abnormality in a person's actions that can be controlled or modulated by the will of the individual. While abnormal behaviors can be difficult to control, they are distinct from other abnormal actions that cannot be affected by the individual's will." ;
rdfs:subClassOf obo:HP_0011446 .
obo:MONDO_0003432 a rdfs:Class ;
rdfs:label "strabismus" ;
rdfs:comment "Strabismus is the intermittent or constant misalignment of an eye so that its line of vision is not pointed at the same object as the other eye. Strabismus is caused by an imbalance in the extraocular muscles which control the positioning of the eyes. Strabismus is normal in newborns but should resolve by the time the baby is 6 months old. In older children with strabismus, the brain may learn to ignore the input from one eye, and this may lead to amblyopia, a potentially permanent decrease in vision in that eye if not corrected." ;
rdfs:subClassOf obo:MONDO_0001584 .
obo:MONDO_0044745 a rdfs:Class ;
rdfs:label "nervous system injury" ;
rdfs:comment "Traumatic injuries to the brain, cranial nerves, spinal cord, autonomic nervous system, or neuromuscular system, including iatrogenic injuries induced by surgical procedures." ;
rdfs:subClassOf obo:MONDO_0005071 , obo:MONDO_0021178 .
obo:MONDO_0021076 a rdfs:Class ;
rdfs:label "pancreatic exocrine neoplasm" ;
rdfs:comment "A benign or malignant neoplasm that arises from the epithelial cells of the exocrine pancreatic tissue." ;
rdfs:subClassOf obo:MONDO_0021040 .
obo:MONDO_0000383 a rdfs:Class ;
rdfs:label "benign reproductive system neoplasm" ;
rdfs:comment "A non-metastasizing neoplasm that arises from the male or female reproductive system. Representative examples include benign prostate phyllodes tumor, benign Sertoli cell tumor, uterine corpus leiomyoma, and benign ovarian serous tumor." ;
rdfs:subClassOf obo:MONDO_0005165 , obo:MONDO_0006054 .
obo:MONDO_0003835 a rdfs:Class ;
rdfs:label "gastric cardia adenocarcinoma" ;
rdfs:comment "A carcinoma that arises from glandular epithelial cells of the cardia of stomach." ;
rdfs:subClassOf obo:MONDO_0003834 , obo:MONDO_0005036 .
obo:HP_5200423 a rdfs:Class ;
rdfs:label "Abnormal experience of reality" ;
rdfs:comment "Subjective phenomena or perceptions that deviate from what is considered correct or are outside the range of normal human experiences." ;
rdfs:subClassOf obo:HP_0011446 .
obo:MONDO_0004980 a rdfs:Class ;
rdfs:label "atopic eczema" ;
rdfs:comment "A common chronic pruritic inflammatory skin disease with a strong genetic component. Onset typically occurs during the first 2 years of life." ;
rdfs:subClassOf obo:MONDO_0002406 , obo:MONDO_0005271 .
obo:MONDO_0005233 a rdfs:Class ;
rdfs:label "non-small cell lung carcinoma" ;
rdfs:comment "A group of at least three distinct histological types of lung cancer, including non-small cell squamous cell carcinoma, adenocarcinoma, and large cell carcinoma. Non-small cell lung carcinomas have a poor response to conventional chemotherapy." ;
rdfs:subClassOf obo:MONDO_0005138 .
obo:MONDO_0002259 a rdfs:Class ;
rdfs:label "gonadal disorder" ;
rdfs:comment "A non-neoplastic or neoplastic disorder that affects the testis or the ovary." ;
rdfs:subClassOf obo:MONDO_0005039 , obo:MONDO_0005151 .
obo:MONDO_0002436 a rdfs:Class ;
rdfs:label "nasal disorder" ;
rdfs:comment "A disease involving the nose." ;
rdfs:subClassOf obo:MONDO_0024623 .
obo:MONDO_0005454 a rdfs:Class ;
rdfs:label "lung neuroendocrine neoplasm" ;
rdfs:comment "A low, intermediate, or high grade malignant neoplasm with neuroendocrine differentiation that arises from the lung. This category includes typical carcinoid tumor, atypical carcinoid tumor, small cell carcinoma, large cell neuroendocrine carcinoma, and combined carcinoma." ;
rdfs:subClassOf obo:MONDO_0019496 , obo:MONDO_0021117 .
obo:MONDO_0006130 a rdfs:Class ;
rdfs:label "central nervous system neoplasm" ;
rdfs:comment "A benign or malignant, primary or metastatic neoplasm that affects the brain, meninges, or spinal cord. Representative examples of primary neoplasms include astrocytoma, oligodendroglioma, ependymoma, and meningioma. Representative examples of metastatic neoplasms include carcinoma and leukemia." ;
rdfs:subClassOf obo:MONDO_0002602 , obo:MONDO_0021248 .
obo:MONDO_0005298 a rdfs:Class ;
rdfs:label "osteoporosis" ;
rdfs:comment "A condition of reduced bone mass, with decreased cortical thickness and a decrease in the number and size of the trabeculae of cancellous bone (but normal chemical composition), resulting in increased fracture incidence. Osteoporosis is classified as primary (Type 1, postmenopausal osteoporosis; Type 2, age-associated osteoporosis; and idiopathic, which can affect juveniles, premenopausal women, and middle-aged men) and secondary osteoporosis (which results from an identifiable cause of bone mass loss)." ;
rdfs:subClassOf obo:MONDO_0000837 , obo:MONDO_0800486 .
obo:HP_0002597 a rdfs:Class ;
rdfs:label "Abnormality of the vasculature" ;
rdfs:comment "An abnormality of the vasculature." ;
rdfs:subClassOf obo:HP_0001626 .
obo:MONDO_0004847 a rdfs:Class ;
rdfs:label "senile cataract" ;
rdfs:comment "A cataract with no obvious cause occurring in persons over 50 years old." ;
rdfs:subClassOf obo:MONDO_0005129 .
obo:ECTO_0070171 a rdfs:Class ;
rdfs:label "exposure to omega-3- fatty acid supplement via ingestion" ;
rdfs:comment "An exposure to omega-3- fatty acid supplement via ingestion." ;
rdfs:subClassOf obo:ECTO_0000015 .
obo:HP_0012539 a rdfs:Class ;
rdfs:label "Non-Hodgkin lymphoma" ;
rdfs:comment "A type of lymphoma characterized microscopically by the absence of multinucleated Reed-Sternberg cells." ;
rdfs:subClassOf obo:HP_0002665 .
obo:MONDO_0100081 a rdfs:Class ;
rdfs:label "sleep disorder" ;
rdfs:comment "A change from the patient's baseline sleeping pattern, in the hours slept and/or an alteration/dysfunction in the stages of sleep." ;
rdfs:subClassOf obo:MONDO_7770007 .
obo:MONDO_0005361 a rdfs:Class ;
rdfs:label "eosinophilic esophagitis" ;
rdfs:comment "Eosinophilic esophagitis (EoE) is a chronic, allergic disease of the esophagus characterized clinically by symptoms of esophageal dysfunction (including vomiting, dysphagia, feeding disorders, food impaction and abdominal pain) which persist after treatment with proton pump inhibitors (PPIs)." ;
rdfs:subClassOf obo:MONDO_0001409 , obo:MONDO_0018438 .
obo:MONDO_0004007 a rdfs:Class ;
rdfs:label "breast intraductal proliferative lesion" ;
rdfs:comment "A group of non-invasive epithelial proliferations that occur in the ductal system of the breast. The vast majority of cases arise in the terminal ductal lobular units. This category includes atypical ductal hyperplasia, usual ductal hyperplasia, flat epithelial atypia, and ductal carcinoma in situ. There is an increased risk for subsequent development of invasive breast carcinoma." ;
rdfs:subClassOf obo:MONDO_0002488 .
obo:MONDO_0005575 a rdfs:Class ;
rdfs:label "colorectal cancer" ;
rdfs:comment "A primary or metastatic malignant neoplasm that affects the colon or rectum. Representative examples include carcinoma, lymphoma, and sarcoma." ;
rdfs:subClassOf obo:MONDO_0005335 , obo:MONDO_0005814 .
obo:MONDO_0100342 a rdfs:Class ;
rdfs:label "malignant glioma" ;
rdfs:comment "A grade III or grade IV glioma arising from the central nervous system. This category includes glioblastoma, anaplastic astrocytoma, anaplastic ependymoma, anaplastic oligodendroglioma, and anaplastic oligoastrocytoma." ;
rdfs:subClassOf obo:MONDO_0002714 , obo:MONDO_0020665 , obo:MONDO_0021042 .
obo:MONDO_0005489 a rdfs:Class ;
rdfs:label "dyslexia" ;
rdfs:comment "A learning disorder characterized by an impairment in processing written words. Reading difficulties can include distortions, omissions or substitutions of characters. Oral and silent reading difficulties can include faulty and slow comprehension." ;
rdfs:subClassOf obo:MONDO_0001697 .
obo:MONDO_0100087 a rdfs:Class ;
rdfs:label "familial Alzheimer disease" ;
rdfs:comment "A degenerative disease of the brain that causes gradual loss of memory, judgment, and the ability to function socially. About 25% of all Alzheimer disease is familial (more than 2 people in a family have AD). When Alzheimer disease begins before 60 or 65 years of age (early-onset AD) about 60% of the cases are familial (also known as Early-onset familial AD). These cases appear to be inherited in an autosomal dominant manner." ;
rdfs:subClassOf obo:MONDO_0004975 , obo:MONDO_0015547 , obo:MONDO_0024237 .
obo:MONDO_0020128 a rdfs:Class ;
rdfs:label "motor neuron disorder" ;
rdfs:comment "Neurological disease involving the motor neuron." ;
rdfs:subClassOf obo:MONDO_0005559 , obo:MONDO_0019056 .
obo:HP_0002360 a rdfs:Class ;
rdfs:label "Sleep disturbance" ;
rdfs:comment "An abnormal pattern in the quality, quantity, or characteristics of sleep." ;
rdfs:subClassOf obo:HP_0011446 .
obo:MONDO_0002031 a rdfs:Class ;
rdfs:label "cecal disorder" ;
rdfs:comment "Pathological developments in the cecum." ;
rdfs:subClassOf obo:MONDO_0003409 .
obo:MONDO_0000637 a rdfs:Class ;
rdfs:label "musculoskeletal system cancer" ;
rdfs:comment "A malignant neoplasm involving the musculoskeletal system" ;
rdfs:subClassOf obo:MONDO_0002081 , obo:MONDO_0004992 .
obo:HP_0011004 a rdfs:Class ;
rdfs:label "Abnormal systemic arterial morphology" ;
rdfs:comment "An abnormality of the systemic arterial tree, which consists of the aorta and other systemic arteries." ;
rdfs:subClassOf obo:HP_0033353 .
obo:MONDO_0005095 a rdfs:Class ;
rdfs:label "spondyloarthropathy" ;
rdfs:comment "A group of inflammatory rheumatic diseases associated with arthritis and enthesitis, and often involving the axial skeleton. The most common form of spondyloarthritis is ankylosing spondylitis. Other forms include axial spondyloarthritis, peripheral spondyloarthritis, reactive arthritis, psoriatic arthritis/spondylitis and enteropathic arthritis/spondylitis." ;
rdfs:subClassOf obo:MONDO_0005046 , obo:MONDO_0006816 .
obo:MONDO_0005281 a rdfs:Class ;
rdfs:label "gallbladder disorder" ;
rdfs:comment "A disease involving the gall bladder." ;
rdfs:subClassOf obo:MONDO_0002515 .
obo:HP_0001600 a rdfs:Class ;
rdfs:label "Abnormality of the larynx" ;
rdfs:comment "An abnormality of the larynx." ;
rdfs:subClassOf obo:HP_0002087 .
obo:HP_0001699 a rdfs:Class ;
rdfs:label "Sudden death" ;
rdfs:comment "Rapid and unexpected death." ;
rdfs:subClassOf obo:HP_0025142 .
obo:MONDO_0021634 a rdfs:Class ;
rdfs:label "epithelial skin neoplasm" ;
rdfs:comment "A epithelial neoplasm that involves the zone of skin." ;
rdfs:subClassOf obo:MONDO_0002531 , obo:MONDO_0005626 .
obo:HP_0030962 a rdfs:Class ;
rdfs:label "Abnormal morphology of the great vessels" ;
rdfs:comment "A structural anomaly affecting a blood vessel involved in the circulation of the heart, i.e., the superior or inferior vena cava, the pulmonary arteries, the pulmonary veins, and the aorta." ;
rdfs:subClassOf obo:HP_0033353 .
obo:HP_0001268 a rdfs:Class ;
rdfs:label "Mental deterioration" ;
rdfs:comment "Loss of previously present mental abilities, generally in adults." ;
rdfs:subClassOf obo:HP_0100543 .
obo:MONDO_0100320 a rdfs:Class ;
rdfs:label "post-COVID-19 disorder" ;
rdfs:comment "A SARS-CoV-2-related disease that is caused by infection by SARS-CoV-2, and manifests after the original primary infection." ;
rdfs:subClassOf obo:MONDO_0021674 .
obo:MONDO_0004995 a rdfs:Class ;
rdfs:label "cardiovascular disorder" ;
rdfs:comment "A disease involving the cardiovascular system." ;
rdfs:subClassOf obo:MONDO_7770006 .
obo:IAO_8000014 a rdfs:Class ;
rdfs:label "generated ontology module"@en ;
rdfs:comment "An ontology module that is automatically generated, for example via a SPARQL query or via template and a CSV."@en ;
rdfs:subClassOf obo:IAO_8000000 .
obo:MONDO_0005012 a rdfs:Class ;
rdfs:label "cutaneous melanoma" ;
rdfs:comment "A primary melanoma arising from atypical melanocytes in the skin. Precursor lesions include acquired and congenital melanocytic nevi, and dysplastic nevi. Several histologic variants have been recognized, including superficial spreading melanoma, acral lentiginous melanoma, nodular melanoma, and lentigo maligna melanoma." ;
rdfs:subClassOf obo:MONDO_0002898 , obo:MONDO_0005105 , obo:MONDO_0021583 .
obo:MONDO_0013282 a rdfs:Class ;
rdfs:label "alpha 1-antitrypsin deficiency" ;
rdfs:comment "Alpha-1-antitrypsin deficiency is a hereditary disease that develops in adulthood and is characterized by chronic liver disorders (cirrhosis), respiratory disorders (emphysema), and rarely panniculitis." ;
rdfs:subClassOf obo:MONDO_0002254 , obo:MONDO_0002273 , obo:MONDO_0005087 .
obo:MONDO_0005292 a rdfs:Class ;
rdfs:label "colitis" ;
rdfs:comment "Inflammation of the colon." ;
rdfs:subClassOf obo:MONDO_0002269 , obo:MONDO_0003409 , obo:MONDO_0005265 .
obo:HP_0000240 a rdfs:Class ;
rdfs:label "Abnormality of skull size" ;
rdfs:comment "Any abnormality of the size of the skull." ;
rdfs:subClassOf obo:HP_0000929 .
obo:MONDO_0008170 a rdfs:Class ;
rdfs:label "ovarian cancer" ;
rdfs:comment "A primary or metastatic malignant neoplasm involving the ovary. Most primary malignant ovarian neoplasms are either carcinomas (serous, mucinous, or endometrioid adenocarcinomas) or malignant germ cell tumors. Metastatic malignant neoplasms to the ovary include carcinomas, lymphomas, and melanomas." ;
rdfs:subClassOf obo:MONDO_0001416 , obo:MONDO_0021068 .
obo:IAO_8000003 a rdfs:Class ;
rdfs:label "main release ontology module"@en ;
rdfs:comment "An ontology module that is intended to be the primary release product and the one consumed by the majority of tools."@en ;
rdfs:subClassOf obo:IAO_8000000 .
obo:MONDO_0005564 a rdfs:Class ;
rdfs:label "embryonal neoplasm" ;
rdfs:comment "A usually malignant neoplasm composed of primitive (immature) tissues that resemble fetal tissues. Medulloblastoma, Ependymoblastoma, Pineoblastoma, and Wilms tumor are representative embryonal neoplasms. --2003" ;
rdfs:subClassOf obo:MONDO_0005070 .
obo:MONDO_0100581 a rdfs:Class ;
rdfs:label "ocular growth disorder" ;
rdfs:comment "An eye disorder characterized by an aberrant development of the eye resulting in significant shortening or elongation, and therefore affecting the final ocular dimensions." ;
rdfs:subClassOf obo:MONDO_0005328 .
obo:MONDO_0002038 a rdfs:Class ;
rdfs:label "head and neck carcinoma" ;
rdfs:comment "A carcinoma that arises from the head and neck region. Representative examples include oral cavity squamous cell carcinoma, laryngeal squamous cell carcinoma, and salivary gland carcinoma." ;
rdfs:subClassOf obo:MONDO_0004993 , obo:MONDO_0005627 .
obo:MONDO_0021392 a rdfs:Class ;
rdfs:label "polyp of large intestine" ;
rdfs:comment "A polyp that involves the large intestine." ;
rdfs:subClassOf obo:MONDO_0005079 , obo:MONDO_0024634 .
obo:ECTO_7000068 a rdfs:Class ;
rdfs:label "exposure to particulate matter" ;
rdfs:comment "A exposure event involving the interaction of an exposure receptor to particulate environmental material." ;
rdfs:subClassOf obo:ECTO_0000015 .
obo:MONDO_0000004 a rdfs:Class ;
rdfs:label "adrenocortical insufficiency" ;
rdfs:comment "An endocrine or hormonal disorder that occurs when the adrenal cortex does not produce enough of the hormone cortisol and in some cases, the hormone aldosterone. It may be due to a disorder of the adrenal cortex (Addison's disease or primary adrenal insufficiency) or to inadequate secretion of ACTH by the pituitary gland (secondary adrenal insufficiency)." ;
rdfs:subClassOf obo:MONDO_0002816 .
obo:MONDO_0003916 a rdfs:Class ;
rdfs:label "overnutrition" ;
rdfs:comment "An imbalanced nutritional status resulting from excessive intake of nutrients. Generally, overnutrition generates an energy imbalance between food consumption and energy expenditure leading to disorders such as obesity." ;
rdfs:subClassOf obo:MONDO_0005137 .
obo:MONDO_0042489 a rdfs:Class ;
rdfs:label "disease susceptibility" ;
rdfs:comment "A constitution or condition of the body which makes the tissues react in special ways to certain extrinsic stimuli and thus tends to make the individual more than usually susceptible to certain diseases." ;
rdfs:subClassOf obo:BFO_0000016 .
obo:ECTO_9000175 a rdfs:Class ;
rdfs:label "exposure to metal cation" ;
rdfs:comment "An exposure to metal cation." ;
rdfs:subClassOf obo:ECTO_9000172 .
obo:MONDO_0700003 a rdfs:Class ;
rdfs:label "obstetric disorder" ;
rdfs:comment "Disorder associated with pregnancy, childbirth, and puerperium." ;
rdfs:subClassOf obo:MONDO_7770007 .
obo:HP_0004324 a rdfs:Class ;
rdfs:label "Increased body weight" ;
rdfs:comment "Abnormally increased body weight." ;
rdfs:subClassOf obo:HP_0004323 .
obo:MONDO_0000001 a rdfs:Class ;
rdfs:label "disease" ;
rdfs:comment "A disease is a disposition to undergo pathological processes that exists in an organism because of one or more disorders in that organism." ;
rdfs:subClassOf obo:BFO_0000016 .
obo:MONDO_0020592 a rdfs:Class ;
rdfs:label "disorder of pharynx" ;
rdfs:comment "A non-neoplastic or neoplastic disorder that affects the pharynx. Representative examples include pharyngitis and carcinoma." ;
rdfs:subClassOf obo:MONDO_0005087 , obo:MONDO_0024623 .
obo:HP_0002795 a rdfs:Class ;
rdfs:label "Abnormal respiratory system physiology" ;
rdfs:comment "Abnormal function of the respiratory system." ;
rdfs:subClassOf obo:HP_0002086 .
obo:MONDO_0003274 a rdfs:Class ;
rdfs:label "thoracic cancer" ;
rdfs:comment "A primary or metastatic malignant neoplasm affecting the tissues of the thorax." ;
rdfs:subClassOf obo:MONDO_0004992 , obo:MONDO_0021350 .
obo:MONDO_0000490 a rdfs:Class ;
rdfs:label "glomerulosclerosis" ;
rdfs:comment "A hardening of the kidney glomerulus caused by scarring of the blood vessels." ;
rdfs:subClassOf obo:MONDO_0019722 .
obo:MONDO_0017341 a rdfs:Class ;
rdfs:label "virus associated tumor" ;
rdfs:subClassOf obo:MONDO_0005070 , obo:MONDO_0021674 .
obo:MONDO_0020753 a rdfs:Class ;
rdfs:label "Orthocoronavirinae infectious disease" ;
rdfs:comment "Infectious disease causes by viruses in the subfamily Orthocoronavirinae (coronaviruses). In humans, coronaviruses cause respiratory tract infections that can be mild, such as some cases of the common cold (among other possible causes, predominantly rhinoviruses), and others that can be lethal, such as SARS, MERS, and COVID-19." ;
rdfs:subClassOf obo:MONDO_0005718 .
obo:ECTO_0000530 a rdfs:Class ;
rdfs:label "exposure to pesticide" ;
rdfs:comment "An exposure to pesticide." ;
rdfs:subClassOf obo:ECTO_0000486 .
obo:MONDO_0005558 a rdfs:Class ;
rdfs:label "ovarian disorder" ;
rdfs:comment "A disease involving the ovary." ;
rdfs:subClassOf obo:MONDO_0002259 , obo:MONDO_0002263 .
obo:MONDO_0013662 a rdfs:Class ;
rdfs:label "Barrett esophagus" ;
rdfs:comment "Esophageal lesion lined with columnar metaplastic epithelium which is flat or villiform. Barrett epithelium is characterized by two different types of cells: goblet cells and columnar cells. The symptomatology of Barrett esophagus is that of gastro-esophageal reflux. It is the precursor of most esophageal adenocarcinomas. (WHO)" ;
rdfs:subClassOf obo:MONDO_0003749 .
obo:MONDO_0000591 a rdfs:Class ;
rdfs:label "intrinsic cardiomyopathy" ;
rdfs:comment "A cardiomyopathy that is due to abnormalities in heart muscle cells." ;
rdfs:subClassOf obo:MONDO_0004994 .
obo:MONDO_0008433 a rdfs:Class ;
rdfs:label "small cell lung carcinoma" ;
rdfs:comment "Small cell lung cancer (SCLC) is a highly aggressive malignant neoplasm, accounting for 10-15% of lung cancer cases, characterized byrapid growth, and early metastasis. SCLC usually manifests as a large hilar mass with bulky mediastinal lymphadenopathy presenting clinically with chest pain, persistent cough, dyspnea, wheezing, hoarseness, hemoptysis, loss of appetite, weight loss, and neurological and endocrine paraneoplastic syndromes. SCLC is primarily reported in elderly people with a history of long-term tobacco exposure." ;
rdfs:subClassOf obo:MONDO_0000402 , obo:MONDO_0005138 , obo:MONDO_0005454 .
obo:MONDO_0002661 a rdfs:Class ;
rdfs:label "uveal disorder" ;
rdfs:comment "A non-neoplastic or neoplastic disorder that affects the uvea. Representative examples include uveitis, chorioretinitis, and uveal melanoma." ;
rdfs:subClassOf obo:MONDO_0005328 .
obo:MONDO_0017594 a rdfs:Class ;
rdfs:label "indolent B-cell non-Hodgkin lymphoma" ;
rdfs:subClassOf obo:MONDO_0015759 .
obo:ECTO_1000000 a rdfs:Class ;
rdfs:label "exposure to environmental condition" ;
rdfs:comment "A exposure event involving the interaction of an exposure receptor to the condition of environmental condition." ;
rdfs:subClassOf obo:ECTO_0010003 .
obo:HP_0000001 a rdfs:Class ;
rdfs:label "All" .
obo:MONDO_0100480 a rdfs:Class ;
rdfs:label "autoimmune primary adrenal insufficiency" ;
rdfs:comment "Diminished production of adrenocortical hormones due to autoimmune destruction of the adrenal glands." ;
rdfs:subClassOf obo:MONDO_0015129 .
obo:ECTO_9000521 a rdfs:Class ;
rdfs:label "exposure to atrazine" ;
rdfs:comment "An exposure to atrazine." ;
rdfs:subClassOf obo:ECTO_0000163 , obo:ECTO_0001152 , obo:ECTO_9002558 .
obo:MONDO_7770007 a rdfs:Class ;
rdfs:label "disease by developmental or physiological process" ;
rdfs:comment "A grouping class for human diseases classified by the molecular, biochemical, cellular, anatomic, developmental or physiological process that is disrupted." ;
rdfs:subClassOf obo:MONDO_0700096 .
obo:ECTO_7000058 a rdfs:Class ;
rdfs:label "exposure to gaseous environmental material" ;
rdfs:comment "A exposure event involving the interaction of an exposure receptor to gaseous environmental material." ;
rdfs:subClassOf obo:ECTO_0000015 .
obo:MONDO_0015128 a rdfs:Class ;
rdfs:label "primary adrenal insufficiency" ;
rdfs:comment "A hormonal disorder that occurs when the adrenal glands fail to release adequate amounts of glucocorticoids (cortisol), mineralocorticoids (aldosterone, 11-deoxycorticosterone), and androgens (dehydroepiandrosterone) to meet physiologic needs, despite release of ACTH from the pituitary." ;
rdfs:subClassOf obo:MONDO_0000004 .
obo:MONDO_0000653 a rdfs:Class ;
rdfs:label "integumentary system cancer" ;
rdfs:comment "A malignant neoplasm involving the integumental system" ;
rdfs:subClassOf obo:MONDO_0002051 , obo:MONDO_0004992 .
obo:ECTO_0000515 a rdfs:Class ;
rdfs:label "exposure to herbicide" ;
rdfs:comment "An exposure to herbicide." ;
rdfs:subClassOf obo:ECTO_0000530 .
obo:MONDO_0021680 a rdfs:Class ;
rdfs:label "streptococcal infection" ;
rdfs:comment "Any of the several infectious disorders caused by members of streptococcus, a genus of gram positive bacteria belonging to the family Streptococcaceae. Streptococcal infections are classified into Groups A, B, C, D and G." ;
rdfs:subClassOf obo:MONDO_0021679 .
obo:MONDO_0700092 a rdfs:Class ;
rdfs:label "neurodevelopmental disorder" ;
rdfs:comment "A behavioral and cognitive disorder with onset during the developmental period that involves impaired or aberrant development of intellectual, motor, or social functions." ;
rdfs:subClassOf obo:MONDO_0005071 .
obo:MONDO_0002465 a rdfs:Class ;
rdfs:label "bronchiolitis" ;
rdfs:comment "Inflammation of the bronchioles characterized by swelling of the bronchioles and mucus accumulation. It is usually caused by the respiratory syncytial virus and affects children. Signs and symptoms include coughing, wheezing, and shortness of breath." ;
rdfs:subClassOf obo:MONDO_0005275 .
obo:MONDO_0005146 a rdfs:Class ;
rdfs:label "post-traumatic stress disorder" ;
rdfs:comment "An anxiety disorder precipitated by an experience of intense fear or horror while exposed to a traumatic (especially life-threatening) event. The disorder is characterized by intrusive recurring thoughts or images of the traumatic event; avoidance of anything associated with the event; a state of hyperarousal and diminished emotional responsiveness. These symptoms are present for at least one month and the disorder is usually long-term." ;
rdfs:subClassOf obo:MONDO_0005379 .
obo:HP_0011015 a rdfs:Class ;
rdfs:label "Abnormal blood glucose concentration" ;
rdfs:comment "An abnormality of the concentration of glucose in the blood." ;
rdfs:subClassOf obo:HP_0011014 , obo:HP_0020347 .
obo:MONDO_0021084 a rdfs:Class ;
rdfs:label "vision disorder" ;
rdfs:comment "Any impairment to the vision." ;
rdfs:subClassOf obo:MONDO_0024458 .
obo:ECTO_9000945 a rdfs:Class ;
rdfs:label "exposure to lead" ;
rdfs:comment "An exposure to lead molecular entity." ;
rdfs:subClassOf obo:ECTO_0000231 .
obo:HP_0000118 a rdfs:Class ;
rdfs:label "Phenotypic abnormality" ;
rdfs:comment "A phenotypic abnormality." ;
rdfs:subClassOf obo:HP_0000001 .
obo:MONDO_0020641 a rdfs:Class ;
rdfs:label "respiratory tract neoplasm" ;
rdfs:comment "A benign or malignant, primary or metastatic neoplasm involving the respiratory tract." ;
rdfs:subClassOf obo:MONDO_0005070 , obo:MONDO_0005087 .
obo:MONDO_0005150 a rdfs:Class ;
rdfs:label "age-related macular degeneration" ;
rdfs:comment "Age-related loss of vision in the central portion of the retina (macula), secondary to retinal degeneration." ;
rdfs:subClassOf obo:MONDO_0002175 , obo:MONDO_0019118 .
obo:MONDO_0022205 a rdfs:Class ;
rdfs:label "pustular psoriasis" ;
rdfs:subClassOf obo:MONDO_0005083 .
obo:MONDO_0005586 a rdfs:Class ;
rdfs:label "head and neck neoplasm" ;
rdfs:comment "A benign or malignant neoplasm that affects the anatomic structures of the head and neck region. Representative examples of benign neoplasms include salivary gland pleomorphic adenoma and nasal cavity papilloma. Representative examples of malignant neoplasms include oral cavity squamous cell carcinoma, laryngeal squamous cell carcinoma, and salivary gland carcinoma." ;
rdfs:subClassOf obo:MONDO_0005070 .
obo:MONDO_0021146 a rdfs:Class ;
rdfs:label "headache disorder" ;
rdfs:comment "Various conditions with the symptom of headache. Headache disorders are classified into major groups, such as primary headache disorders (based on characteristics of their headache symptoms) and secondary headache disorders (based on their etiologies). (International Classification of Headache Disorders, 2nd ed. Cephalalgia 2004: suppl 1)" ;
rdfs:subClassOf obo:MONDO_0700057 .
obo:MONDO_0005590 a rdfs:Class ;
rdfs:label "breast ductal adenocarcinoma" ;
rdfs:comment "A breast carcinoma arising from the ducts. While ductal carcinomas can arise at other sites, this term is universally used to refer to carcinomas of the breast. Ductal carcinomas account for about two thirds of all breast cancers. Two types of ductal carcinomas have been described: ductal carcinoma in situ (DCIS) and invasive ductal carcinoma. The latter often spreads to the axillary lymph nodes and other anatomic sites. The two forms of ductal carcinoma often coexist." ;
rdfs:subClassOf obo:MONDO_0004988 .
obo:MONDO_0005045 a rdfs:Class ;
rdfs:label "hypertrophic cardiomyopathy" ;
rdfs:comment "A condition in which the myocardium is hypertrophied without an obvious cause. The hypertrophy is generally asymmetric and may be associated with obstruction of the ventricular outflow tract." ;
rdfs:subClassOf obo:MONDO_0000591 .
obo:MONDO_0005301 a rdfs:Class ;
rdfs:label "multiple sclerosis" ;
rdfs:comment "A progressive autoimmune disorder affecting the central nervous system resulting in demyelination. Patients develop physical and cognitive impairments that correspond with the affected nerve fibers." ;
rdfs:subClassOf obo:MONDO_0000568 , obo:MONDO_0005560 , obo:MONDO_0006704 , obo:MONDO_0020800 .
obo:ECTO_0900477 a rdfs:Class ;
rdfs:label "exposure to alkaloid via ingestion" ;
rdfs:comment "An exposure to alkaloid via ingestion route." ;
rdfs:subClassOf obo:ECTO_0900407 , obo:ECTO_9000271 .
obo:MONDO_0019527 a rdfs:Class ;
rdfs:label "undifferentiated connective tissue syndrome" ;
rdfs:comment "An autoimmune disorder which does not meet classification criteria used to establish the presence of other well-defined connective tissue diseases." ;
rdfs:subClassOf obo:MONDO_0007179 .
obo:MONDO_0005618 a rdfs:Class ;
rdfs:label "anxiety disorder" ;
rdfs:comment "A category of psychiatric disorders which are characterized by anxious feelings or fear often accompanied by physical symptoms associated with anxiety." ;
rdfs:subClassOf obo:MONDO_0005084 .
obo:HP_0025031 a rdfs:Class ;
rdfs:label "Abnormality of the digestive system" ;
rdfs:subClassOf obo:HP_0000118 .
obo:ECTO_9001696 a rdfs:Class ;
rdfs:label "exposure to agrochemical" ;
rdfs:comment "An exposure to agrochemical." ;
rdfs:subClassOf obo:ECTO_0000486 .
obo:MONDO_0100366 a rdfs:Class ;
rdfs:label "occupational disorder" ;
rdfs:comment "Any disorder that is realized in response to an exposure to occupation." ;
rdfs:subClassOf obo:MONDO_7770010 .
obo:HP_0020172 a rdfs:Class ;
rdfs:label "Adverse drug response" ;
rdfs:comment "An unpleasant or harmful reaction resulting from treatment with a drug." ;
rdfs:subClassOf obo:HP_0020169 .
obo:MONDO_0020076 a rdfs:Class ;
rdfs:label "myeloproliferative neoplasm" ;
rdfs:comment "A clonal hematopoietic stem cell disorder, characterized by proliferation in the bone marrow of one or more of the myeloid (i.e., granulocytic, erythroid, megakaryocytic, and mast cell) lineages. It is primarily a neoplasm of adults. (WHO 2008)" ;
rdfs:subClassOf obo:MONDO_0005170 , obo:MONDO_0015756 , obo:MONDO_0021138 .
obo:MONDO_0011786 a rdfs:Class ;
rdfs:label "allergic rhinitis" ;
rdfs:comment "Inflammation of the nasal mucous membranes caused by an IgE-mediated response to external allergens. The inflammation may also involve the mucous membranes of the sinuses, eyes, middle ear, and pharynx. Symptoms include sneezing, nasal congestion, rhinorrhea, and itching. It may lead to fatigue, drowsiness, and malaise thus causing impairment of the quality of life." ;
rdfs:subClassOf obo:MONDO_0000771 , obo:MONDO_0003014 .
obo:MONDO_0023603 a rdfs:Class ;
rdfs:label "hereditary disorder of connective tissue" ;
rdfs:comment "An inherited genetic disorder that affects the connective tissues. Representative examples include Ehlers-Danlos syndrome and Marfan syndrome." ;
rdfs:subClassOf obo:MONDO_0003847 , obo:MONDO_0003900 .
obo:MONDO_0006999 a rdfs:Class ;
rdfs:label "tooth disorder" ;
rdfs:comment "A disease involving the calcareous tooth." ;
rdfs:subClassOf obo:MONDO_0005172 , obo:MONDO_0006858 .
obo:HP_0011675 a rdfs:Class ;
rdfs:label "Arrhythmia" ;
rdfs:comment "Any cardiac rhythm other than the normal sinus rhythm. Such a rhythm may be either of sinus or ectopic origin and either regular or irregular. An arrhythmia may be due to a disturbance in impulse formation or conduction or both." ;
rdfs:subClassOf obo:HP_0030956 .
obo:MONDO_0001176 a rdfs:Class ;
rdfs:label "lens disorder" ;
rdfs:comment "A disease involving the lens of camera-type eye." ;
rdfs:subClassOf obo:MONDO_0005328 .
obo:MONDO_0958099 a rdfs:Class ;
rdfs:label "idiopathic subglottic stenosis" ;
rdfs:subClassOf obo:MONDO_0004382 .
obo:MONDO_0007256 a rdfs:Class ;
rdfs:label "hepatocellular carcinoma" ;
rdfs:comment "A malignant tumor that arises from hepatocytes. Hepatocellular carcinoma is relatively rare in the United States but very common in all African countries south of the Sahara and in Southeast Asia. Most cases are seen in patients over the age of 50 years, but this tumor can also occur in younger individuals and even in children. Hepatocellular carcinoma is more common in males than females and is associated with hepatitis B, hepatitis C, chronic alcohol abuse and cirrhosis. Serum elevation of alpha-fetoprotein occurs in a large percentage of patients with hepatocellular carcinoma. Grossly, hepatocellular carcinoma may present as a single mass, as multiple nodules, or as diffuse liver involvement. Microscopically, there is a wide range of differentiation from tumor to tumor (well differentiated to poorly differentiated tumors). Hepatocellular carcinomas quickly metastasize to regional lymph nodes and lung. The overall median survival of untreated liver cell carcinoma is about 4 months. The most effective treatment of hepatocellular carcinoma is complete resection of the tumor. Lately, an increasing number of tumors have been treated with liver transplantation." ;
rdfs:subClassOf obo:MONDO_0004970 , obo:MONDO_0018531 .
obo:MONDO_0006502 a rdfs:Class ;
rdfs:label "acute respiratory distress syndrome" ;
rdfs:comment "Progressive and life-threatening pulmonary distress in the absence of an underlying pulmonary condition, usually following major trauma or surgery. Cases of neonatal respiratory distress syndrome are not included in this definition." ;
rdfs:subClassOf obo:MONDO_0001208 , obo:MONDO_0002254 .
obo:MONDO_0100329 a rdfs:Class ;
rdfs:label "primary viral infectious disease" ;
rdfs:comment "The initial viral infectious disase that causes illness." ;
rdfs:subClassOf obo:MONDO_0005108 .
obo:MONDO_0002614 a rdfs:Class ;
rdfs:label "bone inflammation disease" ;
rdfs:comment "Inflammation of the bone." ;
rdfs:subClassOf obo:MONDO_0005381 .
obo:MONDO_0005473 a rdfs:Class ;
rdfs:label "temporomandibular joint disorder" ;
rdfs:comment "Any condition affecting the anatomic and functional characteristics of the temporomandibular joint." ;
rdfs:subClassOf obo:MONDO_0006816 .
obo:MONDO_0005402 a rdfs:Class ;
rdfs:label "lymphoid leukemia" ;
rdfs:comment "A malignant lymphocytic neoplasm of B-cell or T-cell lineage involving primarily the bone marrow and the peripheral blood. This category includes precursor or acute lymphoblastic leukemias and chronic leukemias." ;
rdfs:subClassOf obo:MONDO_0005059 , obo:MONDO_0005157 .
obo:MONDO_0005090 a rdfs:Class ;
rdfs:label "schizophrenia" ;
rdfs:comment "A major psychotic disorder characterized by abnormalities in the perception or expression of reality. It affects the cognitive and psychomotor functions. Common clinical signs and symptoms include delusions, hallucinations, disorganized thinking, and retreat from reality." ;
rdfs:subClassOf obo:MONDO_0005485 .
obo:MONDO_0005399 a rdfs:Class ;
rdfs:label "venous thromboembolism" ;
rdfs:comment "Occlusion of the lumen of a vein by a thrombus that has migrated from a distal site via the blood stream." ;
rdfs:subClassOf obo:MONDO_0005385 .
obo:HP_0001627 a rdfs:Class ;
rdfs:label "Abnormal heart morphology" ;
rdfs:comment "Any structural anomaly of the heart." ;
rdfs:subClassOf obo:HP_0030680 .
obo:MONDO_0005066 a rdfs:Class ;
rdfs:label "metabolic disease" ;
rdfs:comment "A congenital disorder (due to inherited enzyme abnormality) or acquired (due to failure of a metabolically important organ) disorder resulting from an abnormal metabolic process." ;
rdfs:subClassOf obo:MONDO_7770007 .
obo:MONDO_0021065 a rdfs:Class ;
rdfs:label "pleural neoplasm" ;
rdfs:comment "A benign or malignant neoplasm that involves the serous membrane that lines the lungs and thoracic cavity. Most pleural neoplasms are metastatic. Diffuse malignant mesothelioma is the most common primary malignant neoplasm of the pleura." ;
rdfs:subClassOf obo:MONDO_0002037 , obo:MONDO_0020641 .
obo:HP_0002086 a rdfs:Class ;
rdfs:label "Abnormality of the respiratory system" ;
rdfs:comment "An abnormality of the respiratory system, which include the airways, lungs, and the respiratory muscles." ;
rdfs:subClassOf obo:HP_0000118 .
obo:MONDO_0005359 a rdfs:Class ;
rdfs:label "drug-induced liver injury" ;
rdfs:comment "A spectrum of clinical liver diseases ranging from mild biochemical abnormalities to acute liver failure, caused by drugs, drug metabolites, and chemicals from the environment." ;
rdfs:subClassOf obo:MONDO_0005154 .
obo:MONDO_0003218 a rdfs:Class ;
rdfs:label "adenocarcinoma in situ" ;
rdfs:comment "A lesion in which the normally situated glands are partially or completely replaced by atypical cells with malignant characteristics." ;
rdfs:subClassOf obo:MONDO_0004647 , obo:MONDO_0004970 .
obo:HP_0001977 a rdfs:Class ;
rdfs:label "Abnormal thrombosis" ;
rdfs:comment "Venous or arterial thrombosis (formation of blood clots) of spontaneous nature and which cannot be fully explained by acquired risk (e.g. atherosclerosis)." ;
rdfs:subClassOf obo:HP_0001871 .
obo:MONDO_0040679 a rdfs:Class ;
rdfs:label "urothelial carcinoma" ;
rdfs:comment "A malignant neoplasm derived from the transitional epithelium of the urinary tract (urinary bladder, ureter, urethra, or renal pelvis). It is frequently papillary." ;
rdfs:subClassOf obo:MONDO_0006295 , obo:MONDO_0006474 , obo:MONDO_0024337 .
obo:MONDO_0005377 a rdfs:Class ;
rdfs:label "nephrotic syndrome" ;
rdfs:comment "A collection of symptoms that include severe edema, proteinuria, and hypoalbuminemia; it is indicative of renal dysfunction." ;
rdfs:subClassOf obo:MONDO_0002254 , obo:MONDO_0002331 .
obo:MONDO_0018102 a rdfs:Class ;
rdfs:label "corneal dystrophy" ;
rdfs:comment "The term corneal dystrophy embraces a heterogeneous group of bilateral genetically determined non-inflammatory corneal diseases that are usually restricted to the cornea. The designation is imprecise but remains in vogue because of its clinical value." ;
rdfs:subClassOf obo:MONDO_0000942 .
obo:MONDO_0005814 a rdfs:Class ;
rdfs:label "intestinal cancer" ;
rdfs:comment "A malignant neoplasm involving the intestine" ;
rdfs:subClassOf obo:MONDO_0002516 , obo:MONDO_0021118 .
obo:ECTO_0001082 a rdfs:Class ;
rdfs:label "exposure to alcohol consumption" ;
rdfs:comment "An exposure event involving Alcohol Consumption" ;
rdfs:subClassOf obo:ECTO_6000016 .
obo:MONDO_0018687 a rdfs:Class ;
rdfs:label "progressive muscular atrophy" ;
rdfs:comment "A rare, milder form of amyotrophic lateral sclerosis. It is characterized by a slowly progressive clinical course. Signs and symptoms include muscle weakness, atrophy, and fasciculation." ;
rdfs:subClassOf obo:MONDO_0004976 .
obo:HP_0032169 a rdfs:Class ;
rdfs:label "Severe infection" ;
rdfs:comment "A type of infection that is regarded as a sign of a pathological susceptibility to infection because of unusual severity or intensity of the infection." ;
rdfs:subClassOf obo:HP_0032101 .
obo:ECTO_6000038 a rdfs:Class ;
rdfs:label "exposure to Cigarette Smoking" ;
rdfs:comment "An exposure event involving Cigarette Smoking" ;
rdfs:subClassOf obo:ECTO_6000029 .
obo:MONDO_0005157 a rdfs:Class ;
rdfs:label "lymphoid neoplasm" ;
rdfs:comment "A neoplasm composed of a lymphocytic cell population which is usually malignant (clonal) by molecular genetic and/or immunophenotypic analysis. Lymphocytic neoplasms include Hodgkin and non-Hodgkin lymphomas, acute and chronic lymphocytic leukemias, and plasma cell neoplasms." ;
rdfs:subClassOf obo:MONDO_0044881 .
obo:MONDO_0005607 a rdfs:Class ;
rdfs:label "chronic bronchitis" ;
rdfs:comment "A type of chronic obstructive pulmonary disease characterized by chronic inflammation in the bronchial tree that results in edema, mucus production, obstruction, and reduced airflow to and from the lung alveoli. The most common cause is tobacco smoking. Signs and symptoms include coughing with excessive mucus production, and shortness of breath." ;
rdfs:subClassOf obo:MONDO_0003781 , obo:MONDO_0005002 .
obo:MONDO_0005495 a rdfs:Class ;
rdfs:label "adrenal gland disorder" ;
rdfs:comment "A disease involving the adrenal gland." ;
rdfs:subClassOf obo:MONDO_0005151 .
obo:ECTO_0900049 a rdfs:Class ;
rdfs:label "exposure to caffeine via ingestion" ;
rdfs:comment "An exposure to caffeine via ingestion route." ;
rdfs:subClassOf obo:ECTO_0900477 , obo:ECTO_9000205 .
obo:MONDO_0005833 a rdfs:Class ;
rdfs:label "lymphatic system disorder" ;
rdfs:comment "A disease involving the lymphatic part of lymphoid system." ;
rdfs:subClassOf obo:MONDO_0044986 .
obo:MONDO_0005039 a rdfs:Class ;
rdfs:label "reproductive system disorder" ;
rdfs:comment "A disease involving the reproductive system." ;
rdfs:subClassOf obo:MONDO_7770006 .
obo:ECTO_0001108 a rdfs:Class ;
rdfs:label "exposure to aflatoxin" ;
rdfs:comment "An exposure to aflatoxin." ;
rdfs:subClassOf obo:ECTO_0000163 , obo:ECTO_0000371 .
obo:ECTO_0000485 a rdfs:Class ;
rdfs:label "exposure to chemical with biological effect" ;
rdfs:comment "An exposure to biological role." ;
rdfs:subClassOf obo:ExO_0000002 .
obo:MONDO_0800178 a rdfs:Class ;
rdfs:label "platinum-induced ototoxicity" ;
rdfs:comment "Progressive, bilateral, and irreversible sensorineural hearing loss as a frequently encountered side effect of platinum-based chemotherapy such as cisplatin and carboplatin." ;
rdfs:subClassOf obo:MONDO_0020678 , obo:MONDO_0029000 .
obo:BFO_0000006 a rdfs:Class ;
rdfs:label "spatial region"@en ;
rdfs:subClassOf obo:BFO_0000141 .
obo:RO_0001025 a rdf:Property ;
rdfs:label "located in"@en ;
rdfs:comment "a relation between two independent continuants, the target and the location, in which the target is entirely within the location"@en ;
rdfs:domain obo:BFO_0000004 ;
rdfs:range .
obo:RO_0000087 a rdf:Property ;
rdfs:label "has role"@en ;
rdfs:comment "a relation between an independent continuant (the bearer) and a role, in which the role specifically depends on the bearer for its existence"@en ;
rdfs:domain obo:BFO_0000004 ;
rdfs:range obo:BFO_0000023 ;
rdfs:subPropertyOf obo:RO_0000053 .
obo:RO_0002215 a rdf:Property ;
rdfs:label "capable of"@en ;
rdfs:comment "A relation between a material entity (such as a cell) and a process, in which the material entity has the ability to carry out the process. " ;
rdfs:domain obo:BFO_0000004 ;
rdfs:range obo:BFO_0000015 ;
rdfs:subPropertyOf obo:RO_0002216 .
obo:RO_0000085 a rdf:Property ;
rdfs:label "has function"@en ;
rdfs:comment "a relation between an independent continuant (the bearer) and a function, in which the function specifically depends on the bearer for its existence"@en ;
rdfs:domain obo:BFO_0000004 ;
rdfs:range obo:BFO_0000034 ;
rdfs:subPropertyOf obo:RO_0000053 .
obo:RO_0000091 a rdf:Property ;
rdfs:label "has disposition"@en ;
rdfs:comment "a relation between an independent continuant (the bearer) and a disposition, in which the disposition specifically depends on the bearer for its existence"@en ;
rdfs:domain obo:BFO_0000004 ;
rdfs:range obo:BFO_0000016 ;
rdfs:subPropertyOf obo:RO_0000053 .
obo:MONDO_0005484 a rdfs:Class ;
rdfs:label "colorectal adenoma" ;
rdfs:comment "An adenoma that arises from the colon or rectum. The group of colorectal adenomas includes tubular, villous, and tubulovillous adenomas, traditional serrated adenomas, sessile serrated adenomas/polyps, and familial adenomatous polyposis." ;
rdfs:subClassOf obo:MONDO_0005335 , obo:MONDO_0006180 .
obo:ECTO_9000250 a rdfs:Class ;
rdfs:label "exposure to nicotine" ;
rdfs:comment "An exposure to nicotine." ;
rdfs:subClassOf obo:ECTO_0000231 .
obo:HP_0003110 a rdfs:Class ;
rdfs:label "Abnormality of urine homeostasis" ;
rdfs:comment "An abnormality of the composition of urine or the levels of its components." ;
rdfs:subClassOf obo:HP_0001939 , obo:HP_0011277 .
obo:MONDO_0003900 a rdfs:Class ;
rdfs:label "connective tissue disorder" ;
rdfs:comment "A disease involving the connective tissue." ;
rdfs:subClassOf obo:MONDO_7770006 .
obo:MONDO_0700007 a rdfs:Class ;
rdfs:label "idiopathic disease" ;
rdfs:comment "A disease or disorder for which the cause is of uncertain or unknown." ;
rdfs:subClassOf obo:MONDO_7770008 .
obo:IAO_8000000 a rdfs:Class ;
rdfs:label "ontology module"@en ;
rdfs:subClassOf obo:IAO_0000102 .
obo:ECTO_0800001 a rdfs:Class ;
rdfs:label "exposure to environmental process route" ;
rdfs:comment "A exposure event involving the interaction of an exposure receptor to environmental system process happening in exposure route of the receptor." ;
rdfs:subClassOf obo:ECTO_8000000 .
obo:HP_0000079 a rdfs:Class ;
rdfs:label "Abnormality of the urinary system" ;
rdfs:comment "An abnormality of the urinary system." ;
rdfs:subClassOf obo:HP_0000119 .
obo:MONDO_0018874 a rdfs:Class ;
rdfs:label "acute myeloid leukemia" ;
rdfs:comment "Acute myeloid leukemia (AML) is a group of neoplasms arising from precursor cells committed to the myeloid cell-line differentiation. All of them are characterized by clonal expansion of myeloid blasts. AML manifests by fever, pallor, anemia, hemorrhages and recurrent infections." ;
rdfs:subClassOf obo:MONDO_0004643 , obo:MONDO_0010643 .
obo:MONDO_0005579 a rdfs:Class ;
rdfs:label "idiopathic generalized epilepsy" ;
rdfs:comment "A generalised epilepsy that encompasses several common seizure phenotypes including childhood absence epilepsy, juvenile absence epilepsy, juvenile myoclonic epilepsy and epilepsy with generalized tonic-clonic seizures alone. These epilepsy syndromes have polygenic inheritance with or without environmental factors contributing to seizure susceptibility. Seizure types include one or a combination of absence seizures, myoclonic seizures and/or generalized tonic-clonic seizures." ;
rdfs:subClassOf obo:MONDO_0100576 .
obo:MONDO_0021211 a rdfs:Class ;
rdfs:label "brain neoplasm" ;
rdfs:comment "A neoplasm (disease) that involves the brain." ;
rdfs:subClassOf obo:MONDO_0005560 , obo:MONDO_0006130 .
obo:HP_0012594 a rdfs:Class ;
rdfs:label "Moderate albuminuria" ;
rdfs:comment "The presence of moderately increased concentrations of albumin in the urine, defined as and albumin-creatinine ratio (ACR) of 30 to 299 mg/gm (3.4 to 34 mg/mmol)." ;
rdfs:subClassOf obo:HP_0012592 .
obo:MONDO_0005296 a rdfs:Class ;
rdfs:label "sleep apnea syndrome" ;
rdfs:comment "A disorder characterized by multiple cessations of respirations during sleep that induce partial arousals and interfere with the maintenance of sleep." ;
rdfs:subClassOf obo:MONDO_0003406 , obo:MONDO_0005087 .
obo:MONDO_0000618 a rdfs:Class ;
rdfs:label "Her2-receptor negative breast cancer" ;
rdfs:subClassOf obo:MONDO_0006116 .
obo:MONDO_0021638 a rdfs:Class ;
rdfs:label "low grade astrocytic tumor" ;
rdfs:comment "A grade I or grade II astrocytic tumor. This category includes pilocytic astrocytoma (grade I), subependymal giant cell astrocytoma (grade I), and diffuse astrocytoma (grade II)." ;
rdfs:subClassOf obo:MONDO_0021636 , obo:MONDO_0021637 .
obo:ECTO_6000027 a rdfs:Class ;
rdfs:label "exposure to social circumstances" ;
rdfs:comment "An exposure event involving Social Circumstances" ;
rdfs:subClassOf obo:ExO_0000002 .
obo:HP_0020347 a rdfs:Class ;
rdfs:label "Abnormal circulating monosaccharide concentration" ;
rdfs:comment "A deviation from the normal concentration of a monosaccharide in the blood circulation." ;
rdfs:subClassOf obo:HP_0011013 .
obo:MONDO_0003409 a rdfs:Class ;
rdfs:label "colonic disorder" ;
rdfs:comment "Pathological processes in the colon region of the large intestine (intestine, large)." ;
rdfs:subClassOf obo:MONDO_0024634 .
obo:MONDO_0005061 a rdfs:Class ;
rdfs:label "lung adenocarcinoma" ;
rdfs:comment "A carcinoma that arises from the lung and is characterized by the presence of malignant glandular epithelial cells. There is a male predilection with a male to female ratio of 2:1. Usually lung adenocarcinoma is asymptomatic and is identified through screening studies or as an incidental radiologic finding. If clinical symptoms are present they include shortness of breath, cough, hemoptysis, chest pain, and fever. Tobacco smoke is a known risk factor." ;
rdfs:subClassOf obo:MONDO_0004970 , obo:MONDO_0005233 .
obo:IAO_8000018 a rdfs:Class ;
rdfs:label "obo basic subset ontology module"@en ;
rdfs:comment """A subset ontology that is designed for basic applications to continue to make certain simplifying assumptions; many of these simplifying assumptions were based on the initial version of the Gene Ontology, and have become enshrined in many popular and useful tools such as term enrichment tools.
Examples of such assumptions include: traversing the ontology graph ignoring relationship types using a naive algorithm will not lead to cycles (i.e. the ontology is a DAG); every referenced term is declared in the ontology (i.e. there are no dangling clauses).
An ontology is OBO Basic if and only if it has the following characteristics:
DAG
Unidirectional
No Dangling Clauses
Fully Asserted
Fully Labeled
No equivalence axioms
Singly labeled edges
No qualifier lists
No disjointness axioms
No owl-axioms header
No imports"""@en ;
rdfs:seeAlso ;
rdfs:subClassOf obo:IAO_8000017 .
obo:MONDO_0013792 a rdfs:Class ;
rdfs:label "intracerebral hemorrhage" ;
rdfs:comment "A cerebrovascular disorder characterized by bleeding into one or both cerebral hemispheres including the basal ganglia and the cerebral cortex. It is often associated with hypertension and craniocerebral trauma." ;
rdfs:subClassOf obo:MONDO_1060199 .
obo:MONDO_0022736 a rdfs:Class ;
rdfs:label "occupational lung disease" ;
rdfs:subClassOf obo:MONDO_0005275 , obo:MONDO_0100366 .
obo:MONDO_0005028 a rdfs:Class ;
rdfs:label "esophageal adenocarcinoma" ;
rdfs:comment "A malignant tumor with glandular differentiation arising predominantly from Barrett mucosa in the lower third of the esophagus. Rare examples of esophageal adenocarcinoma deriving from ectopic gastric mucosa in the upper esophagus have also been reported. Grossly, esophageal adenocarcinomas are similar to esophageal squamous cell carcinomas. Microscopically, adenocarcinomas arising in the setting of Barrett esophagus are typically papillary and/or tubular. The prognosis is poor." ;
rdfs:subClassOf obo:MONDO_0004970 , obo:MONDO_0019086 .
obo:MONDO_0005071 a rdfs:Class ;
rdfs:label "nervous system disorder" ;
rdfs:comment "A non-neoplastic or neoplastic disorder that affects the brain, spinal cord, or peripheral nerves." ;
rdfs:subClassOf obo:MONDO_7770006 .
obo:MONDO_1060213 a rdfs:Class ;
rdfs:label "reticular pseudodrusen" ;
rdfs:comment "A retinal drusen characterized by subretinal deposits located internal to the retinal pigment epithelium, composed of material aggregations in the subretinal space between photoreceptors and the retinal pigment epithelium. These deposits have a bluish-white appearance by biomicroscopy and appear as hyperreflective lesions above the retinal pigment epithelium on optical coherence tomography." ;
rdfs:subClassOf obo:MONDO_0006949 .
obo:HP_0005181 a rdfs:Class ;
rdfs:label "Premature coronary artery atherosclerosis" ;
rdfs:comment "Reduction of the diameter of the coronary arteries as the result of an accumulation of atheromatous plaques within the walls of the coronary arteries before age of 45." ;
rdfs:subClassOf obo:HP_0001677 .
obo:MONDO_0005258 a rdfs:Class ;
rdfs:label "autism spectrum disorder" ;
rdfs:comment "A spectrum of developmental disorders that includes autism, and Asperger syndrome. Signs and symptoms include poor communication skills, defective social interactions, and repetitive behaviors." ;
rdfs:subClassOf obo:MONDO_0000594 .
obo:MONDO_0005371 a rdfs:Class ;
rdfs:label "mood disorder" ;
rdfs:comment "A cognitive disorder a disturbance in which the person's mood is hypothesized to be the main underlying feature." ;
rdfs:subClassOf obo:MONDO_0005084 .
obo:MONDO_0019118 a rdfs:Class ;
rdfs:label "inherited retinal dystrophy" ;
rdfs:comment "An instance of retinal degeneration that is caused by an inherited modification of the individual's genome." ;
rdfs:subClassOf obo:MONDO_0004580 , obo:MONDO_0100545 .
obo:MONDO_0005406 a rdfs:Class ;
rdfs:label "gestational diabetes" ;
rdfs:comment "Carbohydrate intolerance first diagnosed during pregnancy." ;
rdfs:subClassOf obo:MONDO_0005015 , obo:MONDO_0024575 .
obo:MONDO_0002118 a rdfs:Class ;
rdfs:label "urinary system disorder" ;
rdfs:comment "A disease involving the renal system." ;
rdfs:subClassOf obo:MONDO_7770006 .
obo:MONDO_0005180 a rdfs:Class ;
rdfs:label "Parkinson disease" ;
rdfs:comment "A progressive degenerative disorder of the central nervous system characterized by loss of dopamine producing neurons in the substantia nigra and the presence of Lewy bodies in the substantia nigra and locus coeruleus. Signs and symptoms include tremor which is most pronounced during rest, muscle rigidity, slowing of the voluntary movements, a tendency to fall back, and a mask-like facial expression." ;
rdfs:subClassOf obo:MONDO_0021095 , obo:MONDO_0100545 .
obo:MONDO_0021355 a rdfs:Class ;
rdfs:label "neoplasm of esophagus" ;
rdfs:comment "A neoplasm (disease) that involves the esophagus." ;
rdfs:subClassOf obo:MONDO_0003749 , obo:MONDO_0021223 .
obo:MONDO_0005151 a rdfs:Class ;
rdfs:label "endocrine system disorder" ;
rdfs:comment "A disease involving the endocrine system." ;
rdfs:subClassOf obo:MONDO_7770006 .
obo:HP_0011277 a rdfs:Class ;
rdfs:label "Abnormality of the urinary system physiology" ;
rdfs:subClassOf obo:HP_0000079 .
obo:MONDO_0005386 a rdfs:Class ;
rdfs:label "peripheral arterial disease" ;
rdfs:comment "A disorder of the arteries supplying the upper and lower extremity and the visceral organs. This includes the mesenteric arteries, the renal arteries and the aorta and excludes cerebrovascular arterial disease. Patients experience cramping and pain usually in the calves and thighs while walking. The symptoms subside with rest." ;
rdfs:subClassOf obo:MONDO_0000473 , obo:MONDO_0005294 .
obo:MONDO_0004200 a rdfs:Class ;
rdfs:label "superficial urinary bladder carcinoma" ;
rdfs:comment "A term used by urologists to describe an infiltrating carcinoma of the bladder that has not invaded into the muscularis propria of the bladder wall regardless of histologic type or grade." ;
rdfs:subClassOf obo:MONDO_0004986 .
obo:ECTO_0070245 a rdfs:Class ;
rdfs:label "exposure to dietary supplement, vitamin(s) and fatty acids via ingestion" ;
rdfs:comment "An exposure to dietary supplement, vitamin(s) and fatty acids via ingestion." ;
rdfs:subClassOf obo:ECTO_0000015 .
obo:MONDO_0005229 a rdfs:Class ;
rdfs:label "bacterial infectious disease with sepsis" ;
rdfs:comment "An infectious disease caused by bacteria causing sepsis." ;
rdfs:subClassOf obo:MONDO_0005113 , obo:MONDO_1040015 .
obo:MONDO_0016362 a rdfs:Class ;
rdfs:label "attenuated familial adenomatous polyposis" ;
rdfs:comment "Attenuated familial adenomatous polyposis (AFAP) is a mild form of familial adenomatous polyposis characterized by the presence of fewer than 100 adenomatous colonic polyps, a more proximal colonic location, a delayed age of colorectal cancer (CRC) onset and a more limited expression of the extracolonic features." ;
rdfs:subClassOf obo:MONDO_0021057 .
obo:ECTO_9000172 a rdfs:Class ;
rdfs:label "exposure to inorganic compound" ;
rdfs:comment "An exposure to inorganic molecular entity." ;
rdfs:subClassOf obo:ECTO_0000231 .
obo:MONDO_0056798 a rdfs:Class ;
rdfs:label "disorder of appendix" ;
rdfs:comment "A disease or disorder that involves the vermiform appendix." ;
rdfs:subClassOf obo:MONDO_0024634 .
obo:HP_0001681 a rdfs:Class ;
rdfs:label "Angina pectoris" ;
rdfs:comment "Paroxysmal chest pain that occurs with exertion or stress and is related to myocardial ischemia." ;
rdfs:subClassOf obo:HP_0011025 .
obo:MONDO_0004126 a rdfs:Class ;
rdfs:label "thyroiditis" ;
rdfs:comment "Inflammation of the thyroid gland. This category includes Hashimoto thyroiditis, Riedel thyroiditis, acute thyroiditis, subacute thyroiditis, and radiation-induced thyroiditis." ;
rdfs:subClassOf obo:MONDO_0003240 , obo:MONDO_0021166 .
obo:MONDO_0005109 a rdfs:Class ;
rdfs:label "HIV infectious disease" ;
rdfs:comment "An infection caused by the human immunodeficiency virus." ;
rdfs:subClassOf obo:MONDO_0021682 , obo:MONDO_0022034 .
obo:HP_0000478 a rdfs:Class ;
rdfs:label "Abnormality of the eye" ;
rdfs:comment "Any abnormality of the eye, including location, spacing, and intraocular abnormalities." ;
rdfs:subClassOf obo:HP_0000118 .
obo:HP_0003124 a rdfs:Class ;
rdfs:label "Hypercholesterolemia" ;
rdfs:comment "An increased concentration of cholesterol in the blood." ;
rdfs:subClassOf obo:HP_0003107 .
obo:IAO_8000010 a rdfs:Class ;
rdfs:label "exclusion subset ontology module"@en ;
rdfs:comment "A subset of an ontology that is intended to be excluded for some purpose. For example, a blacklist of classes."@en ;
rdfs:subClassOf obo:IAO_8000006 .
obo:ECTO_9000056 a rdfs:Class ;
rdfs:label "exposure to biphenyls" ;
rdfs:comment "An exposure to biphenyls." ;
rdfs:subClassOf obo:ECTO_0000163 .
obo:MONDO_0018908 a rdfs:Class ;
rdfs:label "non-Hodgkin lymphoma" ;
rdfs:comment "Distinct from Hodgkin lymphoma both morphologically and biologically, non-Hodgkin lymphoma (NHL) is characterized by the absence of Reed-Sternberg cells, can occur at any age, and usually presents as a localized or generalized lymphadenopathy associated with fever and weight loss. The clinical course varies according to the morphologic type. NHL is clinically classified as indolent, aggressive, or having a variable clinical course. NHL can be of B-or T-/NK-cell lineage." ;
rdfs:subClassOf obo:MONDO_0005062 .
obo:MONDO_0003308 a rdfs:Class ;
rdfs:label "pleural mesothelioma" ;
rdfs:comment "A neoplasm that arises from the mesothelial cells of the pleura. The primary cause is exposure to asbestos. The major histologic variants are the epithelioid malignant mesothelioma, desmoplastic malignant mesothelioma, and sarcomatoid malignant mesothelioma. Patients present with persistent cough and shortness of breath." ;
rdfs:subClassOf obo:MONDO_0005065 , obo:MONDO_0021065 .
obo:ECTO_9001353 a rdfs:Class ;
rdfs:label "exposure to phenols" ;
rdfs:comment "An exposure to phenols." ;
rdfs:subClassOf obo:ECTO_0000163 , obo:ECTO_0000371 .
obo:MONDO_0004095 a rdfs:Class ;
rdfs:label "B-cell neoplasm" ;
rdfs:comment "A group of heterogeneous lymphoid tumors generally expressing one or more B-cell antigens or representing malignant transformations of B-lymphocytes." ;
rdfs:subClassOf obo:MONDO_0004805 , obo:MONDO_0005062 .
obo:MONDO_0100163 a rdfs:Class ;
rdfs:label "COVID-19–associated multisystem inflammatory syndrome in children" ;
rdfs:comment "A inflammatory syndrome in children infected by the SARS-CoV-2 with similarities to Kawasaki disease. Clinical manifestations range from fever and inflammation to myocardial injury, shock, and development of coronary artery aneurysms." ;
rdfs:subClassOf obo:MONDO_0005108 , obo:MONDO_0035375 .
obo:ECTO_0900473 a rdfs:Class ;
rdfs:label "exposure to sodium chloride via ingestion" ;
rdfs:comment "An exposure to sodium chloride via ingestion route." ;
rdfs:subClassOf obo:ECTO_0900042 , obo:ECTO_9001347 .
obo:MONDO_0019040 a rdfs:Class ;
rdfs:label "chromosomal disorder" ;
rdfs:comment "Clinical conditions caused by an abnormal chromosome constitution in which there is extra or missing chromosome material (either a whole chromosome or a chromosome segment). (from Thompson et al., Genetics in Medicine, 5th ed, p429)" ;
rdfs:subClassOf obo:MONDO_7770009 .
obo:MONDO_0005009 a rdfs:Class ;
rdfs:label "congestive heart failure" ;
rdfs:comment "Failure of the heart to pump a sufficient amount of blood to meet the needs of the body tissues, resulting in tissue congestion and edema. Signs and symptoms include shortness of breath, pitting edema, enlarged tender liver, engorged neck veins, and pulmonary rales." ;
rdfs:subClassOf obo:MONDO_0005252 .
obo:ECTO_8000045 a rdfs:Class ;
rdfs:label "exposure to gamma radiation" ;
rdfs:comment "A exposure event involving the interaction of an exposure receptor to gamma-ray radiation." ;
rdfs:subClassOf obo:ECTO_7000047 .
obo:HP_0000504 a rdfs:Class ;
rdfs:label "Abnormality of vision" ;
rdfs:comment "Abnormality of eyesight (visual perception)." ;
rdfs:subClassOf obo:HP_0012373 .
obo:HP_0002634 a rdfs:Class ;
rdfs:label "Arteriosclerosis" ;
rdfs:comment "Sclerosis (hardening) of the arteries with increased thickness of the wall of arteries as well as increased stiffness and a loss of elasticity." ;
rdfs:subClassOf obo:HP_0011004 .
obo:HP_0004370 a rdfs:Class ;
rdfs:label "Abnormality of temperature regulation" ;
rdfs:comment "An abnormality of temperature homeostasis." ;
rdfs:subClassOf obo:HP_0012337 .
obo:MONDO_0000837 a rdfs:Class ;
rdfs:label "bone resorption disease" ;
rdfs:comment "A disease that has its basis in the disruption of bone resorption. Bone resorption is a process in which specialized cells known as osteoclasts degrade the organic and inorganic portions of bone, and endocytose and transport the degradation products." ;
rdfs:subClassOf obo:MONDO_0000833 .
obo:MONDO_0002129 a rdfs:Class ;
rdfs:label "bone cancer" ;
rdfs:comment "A primary or metastatic malignant neoplasm affecting the bone or articular cartilage." ;
rdfs:subClassOf obo:MONDO_0000637 , obo:MONDO_0019060 .
obo:MONDO_0005023 a rdfs:Class ;
rdfs:label "ductal breast carcinoma in situ" ;
rdfs:comment "A carcinoma entirely confined to the mammary ducts. It is also known as DCIS. There is no evidence of invasion of the basement membrane. Currently, it is classified into three categories: High-grade DCIS, intermediate-grade DCIS and low-grade DCIS. In this classification the DCIS grade is defined by a combination of nuclear grade, architectural growth pattern and presence of necrosis. The size of the lesion as well as the grade and the clearance margins play a major role in dictating the most appropriate therapy for DCIS." ;
rdfs:subClassOf obo:MONDO_0003218 , obo:MONDO_0004007 , obo:MONDO_0004658 , obo:MONDO_0005590 .
obo:HP_0001662 a rdfs:Class ;
rdfs:label "Bradycardia" ;
rdfs:comment "A slower than normal heart rate (in adults, slower than 60 beats per minute)." ;
rdfs:subClassOf obo:HP_0011675 .
obo:MONDO_0002516 a rdfs:Class ;
rdfs:label "digestive system cancer" ;
rdfs:comment "A primary or metastatic malignant neoplasm involving any part of the digestive system." ;
rdfs:subClassOf obo:MONDO_0004335 , obo:MONDO_0004992 , obo:MONDO_0021223 .
obo:MONDO_0021348 a rdfs:Class ;
rdfs:label "neoplasm of testis" ;
rdfs:comment "A neoplasm (disease) that involves the testis." ;
rdfs:subClassOf obo:MONDO_0002329 , obo:MONDO_0024582 .
obo:ECTO_0900369 a rdfs:Class ;
rdfs:label "exposure to micronutrient via ingestion" ;
rdfs:comment "An exposure to micronutrient via ingestion route." ;
rdfs:subClassOf obo:ECTO_0900056 , obo:ECTO_9001687 .
obo:MONDO_0004891 a rdfs:Class ;
rdfs:label "hyperopia" ;
rdfs:comment "A refractive error in which rays of light entering the eye parallel to the optic axis are brought to a focus behind the retina, as a result of the eyeball being too short from front to back. It is also called farsightedness because the near point is more distant than it is in emmetropia with an equal amplitude of accommodation. (Dorland, 27th ed)" ;
rdfs:subClassOf obo:MONDO_0004892 .
obo:HP_0011451 a rdfs:Class ;
rdfs:label "Primary microcephaly" ;
rdfs:comment "Head circumference below 2 standard deviations below the mean for age and gender at birth." ;
rdfs:subClassOf obo:HP_0000252 .
obo:MONDO_0002529 a rdfs:Class ;
rdfs:label "skin squamous cell carcinoma" ;
rdfs:comment "A carcinoma arising from the squamous cells of the epidermis. Skin squamous cell carcinoma is most commonly found on sun-exposed areas. The majority of the tumors are well-differentiated." ;
rdfs:subClassOf obo:MONDO_0002656 , obo:MONDO_0005096 .
obo:HP_0003119 a rdfs:Class ;
rdfs:label "Abnormal circulating lipid concentration" ;
rdfs:comment "Any deviation from the normal concentration of lipid in the blood circulation." ;
rdfs:subClassOf obo:HP_0430071 .
obo:MONDO_0005172 a rdfs:Class ;
rdfs:label "skeletal system disorder" ;
rdfs:comment "A disease involving the skeletal system." ;
rdfs:subClassOf obo:MONDO_0002081 .
obo:MONDO_0025294 a rdfs:Class ;
rdfs:label "tick-borne infectious disease" ;
rdfs:comment "Bacterial, viral, or parasitic diseases transmitted to humans and animals by the bite of infected ticks. The families Ixodidae and Argasidae contain many bloodsucking species that are important pests of man and domestic birds and mammals and probably exceed all other arthropods in the number and variety of disease agents they transmit. Many of the tick-borne diseases are zoonotic." ;
rdfs:subClassOf obo:MONDO_0100120 .
obo:HP_0011793 a rdfs:Class ;
rdfs:label "Neoplasm by anatomical site" ;
rdfs:comment "Neoplasm categorized according to the anatomical site of origin of the neoplasm." ;
rdfs:subClassOf obo:HP_0002664 .
obo:MONDO_0024625 a rdfs:Class ;
rdfs:label "disorder of lacrimal gland" ;
rdfs:comment "A disease that involves the lacrimal gland." ;
rdfs:subClassOf obo:MONDO_0001854 .
obo:MONDO_0037256 a rdfs:Class ;
rdfs:label "serous neoplasm" ;
rdfs:subClassOf obo:MONDO_0024276 .
obo:ECTO_0000200 a rdfs:Class ;
rdfs:label "exposure to lipid" ;
rdfs:comment "An exposure to lipid." ;
rdfs:subClassOf obo:ECTO_0000135 .
obo:MONDO_0009831 a rdfs:Class ;
rdfs:label "malignant pancreatic neoplasm" ;
rdfs:comment "A malignant neoplasm involving the pancreas." ;
rdfs:subClassOf obo:MONDO_0002516 , obo:MONDO_0021040 .
obo:MONDO_0020122 a rdfs:Class ;
rdfs:label "acquired idiopathic inflammatory myopathy" ;
rdfs:comment "An umbrella term for diseases which have chronic muscle inflammation and weakness of unknown etiology. The types of idiopathic inflammatory myopathy are further defined by either clinicopathologic criteria or by the presence of certain autoantibodies." ;
rdfs:subClassOf obo:MONDO_0016105 , obo:MONDO_0600023 , obo:MONDO_0700007 .
obo:ECTO_9000185 a rdfs:Class ;
rdfs:label "exposure to nitrate" ;
rdfs:comment "An exposure to nitrate." ;
rdfs:subClassOf obo:ECTO_0000371 , obo:ECTO_9000172 , obo:ECTO_9000404 .
obo:MONDO_0006486 a rdfs:Class ;
rdfs:label "uveal melanoma" ;
rdfs:comment "A melanoma derived from melanocytes of the uveal tract. It is the most common primary intraocular tumor in the United States and Western Europe. Similar to melanoma of the skin, it is rare in Africa and Asia. Diagnostic procedures include ophthalmoscopic exam, fluorescein angiography and ultrasound. Treatment includes: surgical excision of the eye, iridocyclectomy and tumor resection. Recent treatments also include radiotherapy or photo coagulation. Classification of uveal melanomas recognizes four cell types within these tumors: epithelioid, intermediate, mixed cell, and spindle cell types. The spindle cell type uveal melanomas are further sub-classified as spindle cell type A and spindle cell type B." ;
rdfs:subClassOf obo:MONDO_0002659 , obo:MONDO_0006325 .
obo:MONDO_0002635 a rdfs:Class ;
rdfs:label "periodontal disorder" ;
rdfs:comment "An inflammatory process of the gingival tissues and/or periodontal membrane of the teeth, resulting in an abnormally deep gingival sulcus, possibly producing periodontal pockets and loss of alveolar bone support." ;
rdfs:subClassOf obo:MONDO_0005172 .
obo:MONDO_0001142 a rdfs:Class ;
rdfs:label "salivary gland disorder" ;
rdfs:comment "A disease involving the saliva-secreting gland." ;
rdfs:subClassOf obo:MONDO_0006858 .
obo:MONDO_0005416 a rdfs:Class ;
rdfs:label "osteoarthritis, knee" ;
rdfs:comment "Noninflammatory degenerative disease of the knee joint consisting of three large categories: conditions that block normal synchronous movement, conditions that produce abnormal pathways of motion, and conditions that cause stress concentration resulting in changes to articular cartilage. (Crenshaw, Campbell's Operative Orthopaedics, 8th ed, p2019)" ;
rdfs:subClassOf obo:MONDO_0005178 .
obo:MONDO_0007147 a rdfs:Class ;
rdfs:label "obstructive sleep apnea syndrome" ;
rdfs:comment "Cessation of air flow during sleep due to upper airway obstruction." ;
rdfs:subClassOf obo:MONDO_0002254 , obo:MONDO_0005296 .
obo:MONDO_0018906 a rdfs:Class ;
rdfs:label "follicular lymphoma" ;
rdfs:comment "Follicular lymphoma is a form of non-Hodgkin lymphoma characterized by a proliferation of B cells whose nodular structure of follicular architecture is preserved." ;
rdfs:subClassOf obo:MONDO_0004949 , obo:MONDO_0017594 .
obo:MONDO_0005397 a rdfs:Class ;
rdfs:label "goiter" ;
rdfs:comment "Enlargement of the thyroid gland usually caused by lack of iodine in the diet, hyperthyroidism, or thyroid nodules. Symptoms include difficulty in breathing and swallowing." ;
rdfs:subClassOf obo:MONDO_0003240 .
obo:ECTO_7000047 a rdfs:Class ;
rdfs:label "exposure to ionizing radiation" ;
rdfs:comment "A exposure event involving the interaction of an exposure receptor to ionizing radiation." ;
rdfs:subClassOf obo:ECTO_0000002 .
obo:MONDO_0021066 a rdfs:Class ;
rdfs:label "urinary system neoplasm" ;
rdfs:comment "A benign or malignant, primary or metastatic neoplasm involving the urinary system. --2003" ;
rdfs:subClassOf obo:MONDO_0002118 , obo:MONDO_0005070 .
obo:MONDO_0001056 a rdfs:Class ;
rdfs:label "gastric cancer" ;
rdfs:comment "A primary or metastatic malignant neoplasm involving the stomach." ;
rdfs:subClassOf obo:MONDO_0002516 , obo:MONDO_0021085 .
obo:MONDO_0021095 a rdfs:Class ;
rdfs:label "parkinsonian disorder" ;
rdfs:comment "A group of disorders which feature impaired motor control characterized by bradykinesia, MUSCLE RIGIDITY; TREMOR; and postural instability. Parkinsonian diseases are generally divided into primary parkinsonism (see PARKINSON DISEASE), secondary parkinsonism (see PARKINSON DISEASE, SECONDARY) and inherited forms. These conditions are associated with dysfunction of dopaminergic or closely related motor integration neuronal pathways in the BASAL GANGLIA." ;
rdfs:subClassOf obo:MONDO_0003996 .
obo:MONDO_0018078 a rdfs:Class ;
rdfs:label "soft tissue sarcoma" ;
rdfs:comment "A malignant neoplasm arising from muscle tissue, adipose tissue, blood vessels, fibrous tissue, or other supportive tissues excluding the bones." ;
rdfs:subClassOf obo:MONDO_0005089 , obo:MONDO_0024637 .
obo:MONDO_0006316 a rdfs:Class ;
rdfs:label "neuroblastic tumor" ;
rdfs:comment "A group of nervous system tumors which display neuronal differentiation. It includes tumors that are composed of immature round cells and tumors that display advanced differentiation and the formation of ganglion cells." ;
rdfs:subClassOf obo:MONDO_0005462 .
obo:ExO_0000002 a rdfs:Class ;
rdfs:label "exposure event" ;
rdfs:comment "An interaction between an exposure stressor and an exposure_receptor." ;
rdfs:subClassOf obo:BFO_0000015 .
obo:MONDO_0002050 a rdfs:Class ;
rdfs:label "depressive disorder" ;
rdfs:comment "A melancholy feeling of sadness and despair." ;
rdfs:subClassOf obo:MONDO_0005371 .
obo:MONDO_0004821 a rdfs:Class ;
rdfs:label "nasopharyngeal disorder" ;
rdfs:comment "A non-neoplastic or neoplastic disorder that affects the nasopharynx. Representative examples include nasopharyngitis, angiofibroma, and carcinoma." ;
rdfs:subClassOf obo:MONDO_0004867 , obo:MONDO_0020592 .
obo:MONDO_0003240 a rdfs:Class ;
rdfs:label "thyroid gland disorder" ;
rdfs:comment "A disease involving the thyroid gland." ;
rdfs:subClassOf obo:MONDO_0005151 .
obo:MONDO_0001187 a rdfs:Class ;
rdfs:label "urinary bladder cancer" ;
rdfs:comment "A primary or metastatic malignant neoplasm involving the bladder." ;
rdfs:subClassOf obo:MONDO_0004987 , obo:MONDO_0006295 .
obo:MONDO_0005168 a rdfs:Class ;
rdfs:label "neoplasm of immature B and T cells" ;
rdfs:comment "A neoplasm arising from immature B and T cells" ;
rdfs:subClassOf obo:MONDO_0005157 .
obo:HP_0001649 a rdfs:Class ;
rdfs:label "Tachycardia" ;
rdfs:comment "A rapid heartrate that exceeds the range of the normal resting heartrate for age." ;
rdfs:subClassOf obo:HP_0011675 .
obo:HP_0030858 a rdfs:Class ;
rdfs:label "Addictive behavior" ;
rdfs:comment "When an activity, substance, object, or behavior becomes a major focus of a person's life, excluding other activities, or has begun to harm the individual or others physically, mentally, or socially, it can be considered addictive behavior. A person can become addicted or compulsively engaged with anything." ;
rdfs:subClassOf obo:HP_5200241 .
obo:HP_0430071 a rdfs:Class ;
rdfs:label "Abnormal circulating organic compound concentration" ;
rdfs:comment "Any deviation of the concentration of an orrganic compound from the normal range. An organic compound is defined as any compound that contains a carbon atom." ;
rdfs:subClassOf obo:HP_0032180 .
obo:MONDO_0001627 a rdfs:Class ;
rdfs:label "dementia" ;
rdfs:comment "Loss of intellectual abilities interfering with an individual's social and occupational functions. Causes include Alzheimer's disease, brain injuries, brain tumors, and vascular disorders." ;
rdfs:subClassOf obo:MONDO_0002039 .
obo:ECTO_6000009 a rdfs:Class ;
rdfs:label "exposure to alcohol abuse" ;
rdfs:comment "An exposure event involving Alcohol Abuse" ;
rdfs:subClassOf obo:ECTO_6000007 .
obo:ECTO_0000537 a rdfs:Class ;
rdfs:label "exposure to toxin" ;
rdfs:comment "An exposure to toxin." ;
rdfs:subClassOf obo:ECTO_9002382 .
obo:MONDO_0005252 a rdfs:Class ;
rdfs:label "heart failure" ;
rdfs:comment "Inability of the heart to pump blood at an adequate rate to meet tissue metabolic requirements. Clinical symptoms of heart failure include: unusual dyspnea on light exertion, recurrent dyspnea occurring in the supine position, fluid retention or rales, jugular venous distension, pulmonary edema on physical exam, or pulmonary edema on chest x-ray presumed to be cardiac dysfunction." ;
rdfs:subClassOf obo:MONDO_0005267 .
obo:MONDO_0004988 a rdfs:Class ;
rdfs:label "breast adenocarcinoma" ;
rdfs:comment "A carcinoma that arises from glandular epithelial cells of the breast" ;
rdfs:subClassOf obo:MONDO_0000653 , obo:MONDO_0004970 , obo:MONDO_0004989 .
obo:ECTO_3000000 a rdfs:Class ;
rdfs:label "exposure to organism" ;
rdfs:comment "A history of exposure to root." ;
rdfs:subClassOf obo:ExO_0000002 .
obo:MONDO_0005929 a rdfs:Class ;
rdfs:label "postpartum depression" ;
rdfs:comment "A type of clinical depression that occurs after childbirth." ;
rdfs:subClassOf obo:MONDO_0002050 .
obo:ECTO_0600000 a rdfs:Class ;
rdfs:label "exposure to environmental system" ;
rdfs:comment "A exposure event involving the interaction of an exposure receptor to environmental system." ;
rdfs:subClassOf obo:ExO_0000002 .
obo:MONDO_0005315 a rdfs:Class ;
rdfs:label "bone fracture" ;
rdfs:comment "Breaks in bones." ;
rdfs:subClassOf obo:MONDO_0021178 .
obo:MONDO_0005265 a rdfs:Class ;
rdfs:label "inflammatory bowel disease" ;
rdfs:comment "A spectrum of small and large bowel inflammatory diseases of unknown etiology. It includes Crohn's disease, ulcerative colitis, and colitis of indeterminate type." ;
rdfs:subClassOf obo:MONDO_0003847 , obo:MONDO_0005020 , obo:MONDO_0005046 .
obo:MONDO_0020799 a rdfs:Class ;
rdfs:label "basal cell neoplasm" ;
rdfs:comment "A neoplastic proliferation of basal cells in the epidermis (part of the skin) or other anatomic sites (most frequently the salivary glands). The basal cell neoplastic proliferation in the epidermis results in basal cell carcinomas. The basal cell neoplastic proliferation in the salivary glands can be benign, resulting in basal cell adenomas or malignant, resulting in basal cell adenocarcinomas." ;
rdfs:subClassOf obo:MONDO_0005626 .
obo:ECTO_6000016 a rdfs:Class ;
rdfs:label "exposure to personal behavior" ;
rdfs:comment "An exposure event involving Personal Behavior" ;
rdfs:subClassOf obo:ECTO_6000000 .
obo:MONDO_0005186 a rdfs:Class ;
rdfs:label "cocaine dependence" ;
rdfs:comment "A psychologically and socially impaired state, with or without physiological changes, that develops as a result of using cocaine and which leads to compulsive behaviors to acquire the substance." ;
rdfs:subClassOf obo:MONDO_0005303 .
obo:MONDO_0010108 a rdfs:Class ;
rdfs:label "testicular germ cell tumor" ;
rdfs:comment "A germ cell tumor arising from the testis. Representative examples include teratoma, seminoma, embryonal carcinoma, and yolk sac tumor." ;
rdfs:subClassOf obo:MONDO_0018202 , obo:MONDO_0021348 .
obo:MONDO_0024647 a rdfs:Class ;
rdfs:label "urolithiasis" ;
rdfs:comment "Stone(s) within the urinary tract." ;
rdfs:subClassOf obo:MONDO_0002118 .
obo:MONDO_0021581 a rdfs:Class ;
rdfs:label "connective tissue neoplasm" ;
rdfs:comment "Neoplasms composed of connective tissue, including elastic, mucous, reticular, osseous, and cartilaginous tissue. The concept does not refer to neoplasms located in connective tissue." ;
rdfs:subClassOf obo:MONDO_0003900 , obo:MONDO_0005070 .
obo:MONDO_0000426 a rdfs:Class ;
rdfs:label "autosomal dominant disease" ;
rdfs:comment "Autosomal dominant form of disease." ;
rdfs:subClassOf obo:MONDO_0000429 .
obo:MONDO_0100637 a rdfs:Class ;
rdfs:label "drug-induced myopathy" ;
rdfs:comment "A myopathy caused by exposure to a drug." ;
rdfs:subClassOf obo:MONDO_0005336 .
obo:MONDO_0006512 a rdfs:Class ;
rdfs:label "estrogen-receptor positive breast cancer" ;
rdfs:comment "A subtype of breast cancer that is estrogen-receptor positive" ;
rdfs:subClassOf obo:MONDO_0006116 .
obo:MONDO_0018531 a rdfs:Class ;
rdfs:label "carcinoma of liver and intrahepatic biliary tract" ;
rdfs:comment "A carcinoma that arises from the hepatocytes or intrahepatic bile ducts. The main subtypes are hepatocellular carcinoma (hepatoma) and cholangiocarcinoma." ;
rdfs:subClassOf obo:MONDO_0002691 , obo:MONDO_0006181 .
obo:HP_0000929 a rdfs:Class ;
rdfs:label "Abnormal skull morphology" ;
rdfs:comment "An abnormality of the skull, the bony framework of the head which is comprised of the neurocranium (with eight cranial bones) and the viscerocranium (facial skeleton) that comprises fourteen facial bones with the mandible as its largest bone." ;
rdfs:subClassOf obo:HP_0000234 , obo:HP_0009121 .
obo:ECTO_7000156 a rdfs:Class ;
rdfs:label "exposure to emissions from petroleum combustion" ;
rdfs:comment "A exposure event involving the interaction of an exposure receptor to emissions from petroleum combustion." ;
rdfs:subClassOf obo:ECTO_0000015 .
obo:MONDO_0005351 a rdfs:Class ;
rdfs:label "anorexia nervosa" ;
rdfs:comment "A disorder most often seen in adolescent females characterized by a refusal to maintain a minimally normal body weight, an intense fear of gaining weight, a disturbance in body image, and, in postmenarcheal females, the development of amenorrhea." ;
rdfs:subClassOf obo:MONDO_0005451 .
obo:MONDO_0003004 a rdfs:Class ;
rdfs:label "macular degeneration" ;
rdfs:comment "Loss of vision in the central portion of the retina (macula), secondary to retinal degeneration." ;
rdfs:subClassOf obo:MONDO_0004580 .
obo:HP_0002140 a rdfs:Class ;
rdfs:label "Ischemic stroke" ;
rdfs:comment "Acute ischemic stroke (AIS) is defined by the sudden loss of blood flow to an area of the brain with the resulting loss of neurologic function. It is caused by thrombosis or embolism that occludes a cerebral vessel supplying a specific area of the brain. During a vessel occlusion, there is a core area where damage to the brain is irreversible and an area of penumbra where the brain has lost function owing to decreased blood flow but is not irreversibly injured." ;
rdfs:subClassOf obo:HP_0001297 , obo:HP_0002637 , obo:HP_0025722 .
obo:MONDO_0006244 a rdfs:Class ;
rdfs:label "HER2 positive breast carcinoma" ;
rdfs:comment "A biologic subset of breast carcinoma defined by high expression of HER2, GRB7, and TRAP100, and by lack of expression of estrogen receptor (ER)." ;
rdfs:subClassOf obo:MONDO_0006116 .
obo:MONDO_0005096 a rdfs:Class ;
rdfs:label "squamous cell carcinoma" ;
rdfs:comment "A carcinoma arising from squamous epithelial cells. Morphologically, it is characterized by the proliferation of atypical, often pleomorphic squamous cells. Squamous cell carcinomas are graded by the degree of cellular differentiation as well, moderately, or poorly differentiated. Well differentiated carcinomas are usually associated with keratin production and the presence of intercellular bridges between adjacent cells. Representative examples are lung squamous cell carcinoma, skin squamous cell carcinoma, and cervical squamous cell carcinoma." ;
rdfs:subClassOf obo:MONDO_0002532 , obo:MONDO_0004993 .
obo:ECTO_6000001 a rdfs:Class ;
rdfs:label "exposure to violence" ;
rdfs:comment "An exposure event involving Violence" ;
rdfs:subClassOf obo:ECTO_6000000 .
obo:MONDO_0010643 a rdfs:Class ;
rdfs:label "acute leukemia" ;
rdfs:comment "A clonal (malignant) hematopoietic disorder with an acute onset, affecting the bone marrow and the peripheral blood. The malignant cells show minimal differentiation and are called blasts, either myeloid blasts (myeloblasts) or lymphoid blasts (lymphoblasts)." ;
rdfs:subClassOf obo:MONDO_0005059 , obo:MONDO_0020683 .
obo:MONDO_0005135 a rdfs:Class ;
rdfs:label "parasitic infectious disease" ;
rdfs:comment "A successful invasion of a host by an organism that uses the host for food and shelter." ;
rdfs:subClassOf obo:MONDO_0005550 .
obo:MONDO_0002367 a rdfs:Class ;
rdfs:label "kidney cancer" ;
rdfs:comment "Primary or metastatic malignant neoplasm involving the kidney." ;
rdfs:subClassOf obo:MONDO_0006295 , obo:MONDO_0021163 .
obo:MONDO_0029000 a rdfs:Class ;
rdfs:label "poisoning" ;
rdfs:comment "A condition or physical state produced by the ingestion, injection, inhalation of or exposure to a deleterious agent." ;
rdfs:subClassOf obo:MONDO_7770010 .
obo:MONDO_0005542 a rdfs:Class ;
rdfs:label "acute coronary syndrome" ;
rdfs:comment "Signs and symptoms related to acute ischemia of the myocardium secondary to coronary artery disease. The clinical presentation covers a spectrum of heart diseases from unstable angina to myocardial infarction." ;
rdfs:subClassOf obo:MONDO_0002254 , obo:MONDO_0020683 , obo:MONDO_0024644 .
obo:MONDO_0005005 a rdfs:Class ;
rdfs:label "clear cell renal carcinoma" ;
rdfs:comment "A malignant epithelial neoplasm of the kidney characterized by the presence of lipid-containing clear cells within a vascular network. The tumor may metastasize to unusual sites and late metastasis is common." ;
rdfs:subClassOf obo:MONDO_0005004 , obo:MONDO_0005549 , obo:MONDO_0007763 .
obo:MONDO_0005062 a rdfs:Class ;
rdfs:label "lymphoma" ;
rdfs:comment "A malignant (clonal) proliferation of B- lymphocytes or T- lymphocytes which involves the lymph nodes, bone marrow and/or extranodal sites. This category includes Non-Hodgkin lymphomas and Hodgkin lymphomas." ;
rdfs:subClassOf obo:MONDO_0005157 , obo:MONDO_0015757 .
obo:ECTO_0001566 a rdfs:Class ;
rdfs:label "exposure to cadmium" ;
rdfs:comment "An exposure to cadmium molecular entity." ;
rdfs:subClassOf obo:ECTO_0000481 .
obo:ECTO_8000061 a rdfs:Class ;
rdfs:label "exposure to Solar radiation" ;
rdfs:comment "A exposure event involving the interaction of an exposure receptor to Solar radiation." ;
rdfs:subClassOf obo:ExO_0000002 .
obo:ECTO_0070133 a rdfs:Class ;
rdfs:label "exposure to tea (steeped) via ingestion" ;
rdfs:comment "An exposure to tea (steeped) via ingestion." ;
rdfs:subClassOf obo:ECTO_0000015 .
obo:HP_0001645 a rdfs:Class ;
rdfs:label "Sudden cardiac death" ;
rdfs:comment "The heart suddenly and unexpectedly stops beating resulting in death within a short time period (generally within 1 h of symptom onset)." ;
rdfs:subClassOf obo:HP_0001695 , obo:HP_0001699 .
obo:HP_0004942 a rdfs:Class ;
rdfs:label "Aortic aneurysm" ;
rdfs:comment "Aortic dilatation refers to a dimension that is greater than the 95th percentile for the normal person age, sex and body size. In contrast, an aneurysm is defined as a localized dilation of the aorta that is more than 150 percent of predicted (ratio of observed to expected diameter 1.5 or more). Aneurysm should be distinguished from ectasia, which represents a diffuse dilation of the aorta less than 50 percent of normal aorta diameter." ;
rdfs:subClassOf obo:HP_0001679 , obo:HP_0002617 .
obo:HP_0012191 a rdfs:Class ;
rdfs:label "B-cell lymphoma" ;
rdfs:comment "A type of lymphoma that originates in B-cells." ;
rdfs:subClassOf obo:HP_0012539 .
obo:MONDO_0019751 a rdfs:Class ;
rdfs:label "autoinflammatory syndrome" ;
rdfs:comment "A group of disorders of the innate immune system characterized by attacks of seemingly unprovoked inflammation without significant levels of either autoantibodies or autoreactive T cells more characteristic of autoimmune disease." ;
rdfs:subClassOf obo:MONDO_0002254 , obo:MONDO_0005554 .
obo:ECTO_0900406 a rdfs:Class ;
rdfs:label "exposure to lipid via ingestion" ;
rdfs:comment "An exposure to lipid via ingestion route." ;
rdfs:subClassOf obo:ECTO_0000200 , obo:ECTO_0900042 .
obo:MONDO_0002657 a rdfs:Class ;
rdfs:label "breast disorder" ;
rdfs:comment "A disease involving the breast." ;
rdfs:subClassOf obo:MONDO_7770006 .
obo:ECTO_2000097 a rdfs:Class ;
rdfs:label "exposure to iron supplementation" ;
rdfs:comment "An exposure to iron supplementation." ;
rdfs:subClassOf obo:ECTO_2000068 .
obo:HP_5200283 a rdfs:Class ;
rdfs:label "Sleep-related breathing disorders" ;
rdfs:comment "Conditions of abnormal and difficult respiration during sleep, including chronic snoring and sleep apnea." ;
rdfs:subClassOf obo:HP_0002360 .
obo:MONDO_0000833 a rdfs:Class ;
rdfs:label "bone remodeling disease" ;
rdfs:comment "A bone disease that results in formation or resorption abnormalities located in bone." ;
rdfs:subClassOf obo:MONDO_0005381 .
obo:MONDO_0001593 a rdfs:Class ;
rdfs:label "rectal disorder" ;
rdfs:comment "A disease that involves the rectum." ;
rdfs:subClassOf obo:MONDO_0024634 .
obo:MONDO_0002545 a rdfs:Class ;
rdfs:label "spinal cord disorder" ;
rdfs:comment "A disease involving the spinal cord." ;
rdfs:subClassOf obo:MONDO_0002602 .
obo:MONDO_0100546 a rdfs:Class ;
rdfs:label "hereditary neuromuscular disease" ;
rdfs:comment "A heterogeneous group of genetic conditions with Mendelian (autosomal dominant, recessive, or X-linked) or chromosomal etiology that is characterized by progressive muscle degeneration and weakness." ;
rdfs:subClassOf obo:MONDO_0019056 , obo:MONDO_0100545 .
obo:MONDO_0009693 a rdfs:Class ;
rdfs:label "plasma cell myeloma" ;
rdfs:comment "A bone marrow-based plasma cell neoplasm characterized by a serum monoclonal protein and skeletal destruction with osteolytic lesions, pathological fractures, bone pain, hypercalcemia, and anemia. Clinical variants include non-secretory myeloma, smoldering myeloma, indolent myeloma, and plasma cell leukemia. (WHO, 2001)" ;
rdfs:subClassOf obo:MONDO_0000621 , obo:MONDO_0004959 , obo:MONDO_0005170 .
obo:ECTO_0900006 a rdfs:Class ;
rdfs:label "exposure to mercury via ingestion" ;
rdfs:comment "An exposure to mercury molecular entity via ingestion route." ;
rdfs:subClassOf obo:ECTO_0001571 , obo:ECTO_0900042 .
a rdfs:Class .
obo:MONDO_0005087 a rdfs:Class ;
rdfs:label "respiratory system disorder" ;
rdfs:comment "A non-neoplastic or neoplastic disorder that affects the respiratory system. Representative examples include pneumonia, chronic obstructive pulmonary disease, pulmonary failure, lung adenoma, lung carcinoma, and tracheal carcinoma." ;
rdfs:subClassOf obo:MONDO_7770006 .
obo:MONDO_0006041 a rdfs:Class ;
rdfs:label "lung carcinoid tumor" ;
rdfs:comment "A neuroendocrine neoplasm that arises from the lung. It is characterized by the presence of uniform polygonal cells with small or moderate amount of cytoplasm and inconspicuous nucleoli. The cells are usually arranged in organoid and trabecular patterns. It is classified as typical or atypical carcinoid tumor based on the number of mitotic figures and the absence or presence of necrosis. Atypical carcinoid tumors have a worse prognosis." ;
rdfs:subClassOf obo:MONDO_0005369 , obo:MONDO_0005454 .
obo:ECTO_0000672 a rdfs:Class ;
rdfs:label "exposure to agonist" ;
rdfs:comment "An exposure to agonist." ;
rdfs:subClassOf obo:ECTO_0000485 .
obo:HP_0011025 a rdfs:Class ;
rdfs:label "Abnormal cardiovascular system physiology" ;
rdfs:comment "Abnormal functionality of the cardiovascular system." ;
rdfs:subClassOf obo:HP_0001626 .
obo:ECTO_0070112 a rdfs:Class ;
rdfs:label "exposure to rye bread via ingestion" ;
rdfs:comment "An exposure to rye bread (enriched) via ingestion." ;
rdfs:subClassOf obo:ECTO_0000015 .
obo:MONDO_0700222 a rdfs:Class ;
rdfs:label "disease related to hematopoietic stem cell transplant" ;
rdfs:comment "Disease that occurs as a consequence of immunosuppression in a recipient of a hematopoietic stem cell transplant, or as a consequence of the transplantation." ;
rdfs:subClassOf obo:MONDO_0700220 .
obo:MONDO_0004355 a rdfs:Class ;
rdfs:label "childhood leukemia" ;
rdfs:comment "An acute or chronic leukemia that occurs during childhood." ;
rdfs:subClassOf obo:MONDO_0005059 , obo:MONDO_0006517 .
obo:MONDO_0002356 a rdfs:Class ;
rdfs:label "pancreas disorder" ;
rdfs:comment "A non-neoplastic or neoplastic disorder that affects the pancreas. Representative examples of non-neoplastic disorders include pancreatitis and pancreatic insufficiency. Representative examples of neoplastic disorders include cystadenomas, carcinomas, lymphomas, and neuroendocrine neoplasms." ;
rdfs:subClassOf obo:MONDO_0004335 , obo:MONDO_0005151 .
obo:MONDO_0005560 a rdfs:Class ;
rdfs:label "brain disorder" ;
rdfs:comment "A disease affecting the brain or part of the brain." ;
rdfs:subClassOf obo:MONDO_0002602 .
obo:MONDO_0850292 a rdfs:Class ;
rdfs:label "subjective cognitive decline" ;
rdfs:comment "A cognitive disorder that is characterized by the presence of significant and persistent cognitive complaints." ;
rdfs:subClassOf obo:MONDO_0002039 .
obo:MONDO_1060199 a rdfs:Class ;
rdfs:label "hemorrhagic stroke" ;
rdfs:comment "A stroke disorder caused by bleeding into the brain parenchyma or surrounding spaces. Hemorrhagic stroke includes intracerebral hemorrhage (bleeding within the brain tissue) and subarachnoid hemorrhage (bleeding in the space between the brain and the surrounding membrane)." ;
rdfs:subClassOf obo:MONDO_0005098 .
obo:MONDO_0000592 a rdfs:Class ;
rdfs:label "specific developmental disorder" ;
rdfs:comment "A developmental disorder of mental health that categorizes specific learning disabilities and developmental disorders affecting coordination." ;
rdfs:subClassOf obo:MONDO_0005503 .
obo:MONDO_0015686 a rdfs:Class ;
rdfs:label "primary peritoneal carcinoma" ;
rdfs:comment "A rare carcinoma that arises from the peritoneum and resembles the malignant surface epithelial-stromal tumors that arise from the ovary. Serous adenocarcinoma is the most common histologic variant. It affects women almost exclusively. The diagnosis of primary peritoneal carcinoma can be made only if both ovaries are not involved by tumor, or, if the ovaries are involved, the tumor is confined to the ovarian surface without invasion of the ovarian stroma and the peritoneal involvement is greater than the ovarian surface involvement." ;
rdfs:subClassOf obo:MONDO_0002113 .
obo:BFO_0000141 a rdfs:Class ;
rdfs:label "immaterial entity"@en ;
rdfs:subClassOf obo:BFO_0000004 .
obo:MONDO_0005040 a rdfs:Class ;
rdfs:label "germ cell tumor" ;
rdfs:comment "A benign or malignant, gonadal or extragonadal neoplasm that originates from germ cells. Representative examples include teratoma, seminoma, embryonal carcinoma, and yolk sac tumor." ;
rdfs:subClassOf obo:MONDO_0005070 .
obo:MONDO_0000473 a rdfs:Class ;
rdfs:label "arterial disorder" ;
rdfs:comment "An impairment of the structure or function of the blood vessels which carry blood away from the heart." ;
rdfs:subClassOf obo:MONDO_0005385 .
obo:MONDO_0002691 a rdfs:Class ;
rdfs:label "liver cancer" ;
rdfs:comment "An epithelial or non-epithelial malignant neoplasm that arises from the liver. Representative examples include hepatocellular carcinoma, intrahepatic cholangiocarcinoma, lymphoma, and sarcoma." ;
rdfs:subClassOf obo:MONDO_0002516 , obo:MONDO_0021069 , obo:MONDO_0024477 .
obo:MONDO_0006497 a rdfs:Class ;
rdfs:label "cerebral palsy" ;
rdfs:comment "A group of disorders affecting the development of movement and posture, often accompanied by disturbances of sensation, perception, cognition, and behavior. It results from damage to the fetal or infant brain." ;
rdfs:subClassOf obo:MONDO_0006496 , obo:MONDO_0044996 .
obo:MONDO_0001265 a rdfs:Class ;
rdfs:label "schizophreniform disorder" ;
rdfs:comment "A disorder that differs from schizophrenia specifically in total duration (schizophreniform disorder lasts at least 1 month but less than 6 months whereas schizophrenia lasts at least 6 months); schizophreniform disorder also typically causes less impairment in the individual's social and occupational functioning." ;
rdfs:subClassOf obo:MONDO_0005485 .
obo:MONDO_0004790 a rdfs:Class ;
rdfs:label "fatty liver disease" ;
rdfs:comment "A reversible condition wherein large vacuoles of triglyceride fat accumulate in liver cells via the process of steatosis." ;
rdfs:subClassOf obo:MONDO_0005154 .
obo:MONDO_0005098 a rdfs:Class ;
rdfs:label "stroke disorder" ;
rdfs:comment "A sudden loss of neurological function secondary to hemorrhage or ischemia in the brain parenchyma due to a vascular event." ;
rdfs:subClassOf obo:MONDO_0011057 .
obo:MONDO_0005027 a rdfs:Class ;
rdfs:label "epilepsy" ;
rdfs:comment "A brain disorder characterized by episodes of abnormally increased neuronal discharge resulting in transient episodes of sensory or motor neurological dysfunction, or psychic dysfunction. These episodes may or may not be associated with loss of consciousness or convulsions." ;
rdfs:subClassOf obo:MONDO_0005560 .
obo:MONDO_0021310 a rdfs:Class ;
rdfs:label "malignant tumor of neck" ;
rdfs:comment "A cancer that involves the neck." ;
rdfs:subClassOf obo:MONDO_0005627 , obo:MONDO_0021351 .
obo:HP_0030956 a rdfs:Class ;
rdfs:label "Abnormality of cardiovascular system electrophysiology" ;
rdfs:comment "An anomaly of the electrical conduction physiology of the heart." ;
rdfs:subClassOf obo:HP_0011025 .
obo:MONDO_0005016 a rdfs:Class ;
rdfs:label "diabetic kidney disease" ;
rdfs:comment "Progressive kidney disorder caused by vascular damage to the glomerular capillaries, in patients with diabetes mellitus. It is usually manifested with nephritic syndrome and glomerulosclerosis." ;
rdfs:subClassOf obo:MONDO_0005066 , obo:MONDO_0005300 .
obo:HP_0025323 a rdfs:Class ;
rdfs:label "Abnormal arterial physiology" ;
rdfs:comment "An anomaly of arterial function." ;
rdfs:subClassOf obo:HP_0030163 .
obo:MONDO_0000462 a rdfs:Class ;
rdfs:label "eye adnexa disorder" ;
rdfs:comment "A disease involving the ocular adnexa." ;
rdfs:subClassOf obo:MONDO_0002022 .
obo:MONDO_0004981 a rdfs:Class ;
rdfs:label "atrial fibrillation" ;
rdfs:comment "A disorder characterized by an electrocardiographic finding of a supraventricular arrhythmia characterized by the replacement of consistent P waves by rapid oscillations or fibrillatory waves that vary in size, shape and timing and are accompanied by an irregular ventricular response. (CDISC)" ;
rdfs:subClassOf obo:MONDO_0007263 .
obo:MONDO_0000314 a rdfs:Class ;
rdfs:label "primary bacterial infectious disease" ;
rdfs:subClassOf obo:MONDO_0005113 .
obo:MONDO_0022034 a rdfs:Class ;
rdfs:label "lentivirus infection" ;
rdfs:comment "Virus diseases caused by the Lentivirus genus. They are multi-organ diseases characterized by long incubation periods and persistent infection." ;
rdfs:subClassOf obo:MONDO_0100329 .
obo:MONDO_0002165 a rdfs:Class ;
rdfs:label "rectal neoplasm" ;
rdfs:comment "A benign or malignant neoplasm that affects the rectum. Representative examples of benign neoplasms include lipoma and leiomyoma. Representative examples of malignant neoplasms include carcinoma, lymphoma, and sarcoma. Rectal adenomas always exhibit epithelial dysplasia and are considered premalignant neoplasms." ;
rdfs:subClassOf obo:MONDO_0001593 , obo:MONDO_0005335 .
obo:MONDO_0021042 a rdfs:Class ;
rdfs:label "glioma" ;
rdfs:comment "A benign or malignant brain and spinal cord tumor that arises from glial cells (astrocytes, oligodendrocytes, ependymal cells). Tumors that arise from astrocytes are called astrocytic tumors or astrocytomas. Tumors that arise from oligodendrocytes are called oligodendroglial tumors. Tumors that arise from ependymal cells are called ependymomas." ;
rdfs:subClassOf obo:MONDO_0021193 .
obo:MONDO_0015759 a rdfs:Class ;
rdfs:label "B-cell non-Hodgkin lymphoma" ;
rdfs:comment "The most common type of non-Hodgkin lymphoma. It includes the most frequently seen morphologic variants which are: diffuse large B-cell lymphoma, follicular lymphoma, small lymphocytic lymphoma and marginal zone B-cell lymphoma. -- 2003" ;
rdfs:subClassOf obo:MONDO_0004095 , obo:MONDO_0018908 .
obo:MONDO_0002277 a rdfs:Class ;
rdfs:label "arteriosclerosis disorder" ;
rdfs:comment "A vascular disorder characterized by thickening and hardening of the walls of the arteries." ;
rdfs:subClassOf obo:MONDO_0000473 .
obo:IAO_8000007 a rdfs:Class ;
rdfs:label "curation subset ontology module"@en ;
rdfs:comment "A subset ontology that is intended as a whitelist for curators using the ontology. Such a subset will exclude classes that curators should not use for curation."@en ;
rdfs:subClassOf obo:IAO_8000006 .
obo:MONDO_0005083 a rdfs:Class ;
rdfs:label "psoriasis" ;
rdfs:comment "An autoimmune condition characterized by red, well-delineated plaques with silvery scales that are usually on the extensor surfaces and scalp. They can occasionally present with these manifestations: pustules; erythema and scaling in intertriginous areas, and erythroderma, that are often distributed on extensor surfaces and scalp." ;
rdfs:subClassOf obo:MONDO_0002406 , obo:MONDO_0005046 , obo:MONDO_0100118 .
obo:MONDO_0018630 a rdfs:Class ;
rdfs:label "hereditary nonpolyposis colon cancer" ;
rdfs:comment "A cancer-predisposing condition characterized by the development of colorectal cancer not associated with colorectal polyposis, endometrial cancer, and various other cancers (such as malignant epithelial tumor of ovary, gastric, biliary tract, small bowel, and urinary tract cancer) that are frequently diagnosed at an early age." ;
rdfs:subClassOf obo:MONDO_0015356 , obo:MONDO_0023113 .
obo:MONDO_0021178 a rdfs:Class ;
rdfs:label "injury" ;
rdfs:comment "Damage inflicted on the body as the direct or indirect result of an external force, with or without disruption of structural continuity." .
obo:ECTO_0070224 a rdfs:Class ;
rdfs:label "exposure to human milk (raw) via ingestion" ;
rdfs:comment "An exposure to human milk (raw) via ingestion." ;
rdfs:subClassOf obo:ECTO_0000015 .
obo:BFO_0000040 a rdfs:Class ;
rdfs:label "material entity"@en ;
rdfs:comment "An independent continuant that is spatially extended whose identity is independent of that of other entities and can be maintained through time."@en ;
rdfs:subClassOf obo:BFO_0000004 .
obo:RO_0002450 a rdf:Property ;
rdfs:label "directly positively regulates activity of" ;
rdfs:comment """The entity A, immediately upstream of the entity B, has an activity that positively regulates an activity performed by B.
For example, A and B may be gene products and binding of B by A positively regulates the kinase activity of B.""" ;
rdfs:domain obo:BFO_0000040 ;
rdfs:range obo:BFO_0000040 ;
rdfs:subPropertyOf obo:RO_0002448 .
obo:RO_0002449 a rdf:Property ;
rdfs:label "directly negatively regulates activity of" ;
rdfs:comment """The entity A, immediately upstream of the entity B, has an activity that negatively regulates an activity performed by B.
For example, A and B may be gene products and binding of B by A negatively regulates the kinase activity of B.""" ;
rdfs:domain obo:BFO_0000040 ;
rdfs:range obo:BFO_0000040 ;
rdfs:subPropertyOf obo:RO_0002448 .
obo:RO_0002448 a rdf:Property ;
rdfs:label "directly regulates activity of" ;
rdfs:comment """The entity A, immediately upstream of the entity B, has an activity that regulates an activity performed by B. For example, A and B may be gene products and binding of B by A regulates the kinase activity of B.
A and B can be physically interacting but not necessarily. Immediately upstream means there are no intermediate entity between A and B.""" ;
rdfs:domain obo:BFO_0000040 ;
rdfs:range obo:BFO_0000040 ;
rdfs:subPropertyOf obo:RO_0011002 , obo:RO_0002436 .
obo:RO_0011002 a rdf:Property ;
rdfs:label "regulates activity of" ;
rdfs:comment "The entity A has an activity that regulates an activity of the entity B. For example, A and B are gene products where the catalytic activity of A regulates the kinase activity of B." ;
rdfs:domain obo:BFO_0000040 ;
rdfs:range obo:BFO_0000040 ;
rdfs:subPropertyOf obo:RO_0002566 .
obo:RO_0002595 a rdf:Property ;
rdfs:label "causal relation between material entity and a process" ;
rdfs:comment "A relationship that holds between a material entity and a process in which causality is involved, with either the material entity or some part of the material entity exerting some influence over the process, or the process influencing some aspect of the material entity." ;
rdfs:domain obo:BFO_0000040 ;
rdfs:range obo:BFO_0000015 ;
rdfs:subPropertyOf obo:RO_0002410 .
obo:RO_0002434 a rdf:Property ;
rdfs:label "interacts with" ;
rdfs:comment "A relationship that holds between two entities in which the processes executed by the two entities are causally connected." ;
rdfs:domain obo:BFO_0000040 ;
rdfs:range obo:BFO_0000040 .
obo:MONDO_0021245 a rdfs:Class ;
rdfs:label "oral cavity neoplasm" ;
rdfs:comment "A neoplasm (disease) that involves the oral cavity." ;
rdfs:subClassOf obo:MONDO_0006858 , obo:MONDO_0021223 .
obo:MONDO_0001866 a rdfs:Class ;
rdfs:label "bipolar I disorder" ;
rdfs:comment "A bipolar disorder that is characterized by at least one manic or mixed episode." ;
rdfs:subClassOf obo:MONDO_0004985 .
obo:MONDO_0004664 a rdfs:Class ;
rdfs:label "helminthiasis" ;
rdfs:comment "A parasitic infection characterized by the infestation with worms, mainly in the intestine." ;
rdfs:subClassOf obo:MONDO_0005135 .
obo:MONDO_0005276 a rdfs:Class ;
rdfs:label "dental caries" ;
rdfs:comment "The decay of a tooth, in which it becomes softened, discolored, and/or porous." ;
rdfs:subClassOf obo:MONDO_0002220 .
obo:MONDO_0004884 a rdfs:Class ;
rdfs:label "eye degenerative disorder" ;
rdfs:comment "A neurodegenerative disease that involves the eye." ;
rdfs:subClassOf obo:MONDO_0005328 .
obo:MONDO_0016044 a rdfs:Class ;
rdfs:label "cleft lip/palate" ;
rdfs:comment "Cleft lip and palate is a fissure type embryopathy extending across the upper lip, nasal base, alveolar ridge and the hard and soft palate." ;
rdfs:subClassOf obo:MONDO_0000358 , obo:MONDO_0021147 .
obo:MONDO_0045002 a rdfs:Class ;
rdfs:label "vertebral disorder" ;
rdfs:comment "A disease or disorder that involves the vertebra." ;
rdfs:subClassOf obo:MONDO_0000812 .
obo:HP_0012639 a rdfs:Class ;
rdfs:label "Abnormal nervous system morphology" ;
rdfs:comment "A structural anomaly of the nervous system." ;
rdfs:subClassOf obo:HP_0000707 .
obo:MONDO_0004956 a rdfs:Class ;
rdfs:label "metastatic prostate carcinoma" ;
rdfs:comment "A carcinoma that arises from the prostate gland and has spread to other anatomic sites." ;
rdfs:subClassOf obo:MONDO_0005159 .
obo:MONDO_0000621 a rdfs:Class ;
rdfs:label "immune system cancer" ;
rdfs:comment "A malignant neoplasm involving the immune system" ;
rdfs:subClassOf obo:MONDO_0004992 , obo:MONDO_0005046 .
obo:MONDO_0001063 a rdfs:Class ;
rdfs:label "cardia cancer" ;
rdfs:comment "A malignant neoplasm involving the cardia of stomach." ;
rdfs:subClassOf obo:MONDO_0001056 .
obo:MONDO_0002869 a rdfs:Class ;
rdfs:label "heart valve disorder" ;
rdfs:comment "A disease involving the cardial valve." ;
rdfs:subClassOf obo:MONDO_0005267 .
obo:MONDO_0001377 a rdfs:Class ;
rdfs:label "vitreous syneresis" ;
rdfs:subClassOf obo:MONDO_0004860 , obo:MONDO_0004884 .
obo:ECTO_2000121 a rdfs:Class ;
rdfs:label "exposure to low fat diet intake" ;
rdfs:comment "An exposure to low fat diet intake." ;
rdfs:subClassOf obo:ECTO_2000068 .
obo:MONDO_0005606 a rdfs:Class ;
rdfs:label "tubular adenocarcinoma" ;
rdfs:comment "An infiltrating adenocarcinoma in which the malignant cells form tubular structures. Representative examples include the tubular breast carcinoma and the gastric tubular adenocarcinoma." ;
rdfs:subClassOf obo:MONDO_0004970 .
obo:HP_0033353 a rdfs:Class ;
rdfs:label "Abnormal blood vessel morphology" ;
rdfs:comment "Any structural anomaly of a blood vessel (artery, arteriole, capillary, venule, or vein)." ;
rdfs:subClassOf obo:HP_0025015 .
obo:MONDO_0001406 a rdfs:Class ;
rdfs:label "peripheral nervous system neoplasm" ;
rdfs:comment "A benign or malignant neoplasm arising from a peripheral nerve or the perineural sheaths." ;
rdfs:subClassOf obo:MONDO_0003620 , obo:MONDO_0021248 .
obo:MONDO_0044881 a rdfs:Class ;
rdfs:label "hematopoietic and lymphoid cell neoplasm" ;
rdfs:comment "A neoplasm arising from hematopoietic cells found in the bone marrow, peripheral blood, lymph nodes and spleen (organs of the hematopoietic system). Hematopoietic cell neoplasms can also involve other anatomic sites (e.g. central nervous system, gastrointestinal tract), either by metastasis, direct tumor infiltration, or neoplastic transformation of extranodal lymphoid tissues. The commonest forms are the various types of leukemia, Hodgkin and non-Hodgkin lymphomas, myeloproliferative neoplasms, and myelodysplastic syndromes." ;
rdfs:subClassOf obo:MONDO_0002334 .
obo:MONDO_0021092 a rdfs:Class ;
rdfs:label "fallopian tube neoplasm" ;
rdfs:comment "A benign or malignant neoplasm affecting the fallopian tube. Representative examples of benign neoplasms include papilloma, adenofibroma, and leiomyoma. Representative examples of malignant neoplasms include carcinoma, carcinosarcoma, and adenosarcoma." ;
rdfs:subClassOf obo:MONDO_0002156 , obo:MONDO_0021148 .
obo:HP_0000855 a rdfs:Class ;
rdfs:label "Insulin resistance" ;
rdfs:comment "Increased resistance towards insulin, that is, diminished effectiveness of insulin in reducing blood glucose levels." ;
rdfs:subClassOf obo:HP_0011014 .
obo:MONDO_0005327 a rdfs:Class ;
rdfs:label "hip fracture" ;
rdfs:comment "Traumatic or pathological injury to the hip in which the continuity of either the femoral head, femoral neck, intertrochanteric or subtrochanteric regions is broken. Symptoms include pain in the hip or groin, bruising and swelling in and around the hip area. The injured hip is turned outward and the leg appears shorter on that side." ;
rdfs:subClassOf obo:MONDO_0005315 .
obo:HP_0002715 a rdfs:Class ;
rdfs:label "Abnormality of the immune system" ;
rdfs:comment "An abnormality of the immune system." ;
rdfs:subClassOf obo:HP_0000118 .
obo:ECTO_0000509 a rdfs:Class ;
rdfs:label "exposure to drug" ;
rdfs:comment "An exposure to drug." ;
rdfs:subClassOf obo:ECTO_0000486 .
obo:MONDO_0004967 a rdfs:Class ;
rdfs:label "acute lymphoblastic leukemia" ;
rdfs:comment "Leukemia with an acute onset, characterized by the presence of lymphoblasts in the bone marrow and the peripheral blood. It includes the acute B lymphoblastic leukemia and acute T lymphoblastic leukemia." ;
rdfs:subClassOf obo:MONDO_0003538 , obo:MONDO_0005168 , obo:MONDO_0005402 , obo:MONDO_0010643 , obo:MONDO_0018908 .
obo:MONDO_0024623 a rdfs:Class ;
rdfs:label "otorhinolaryngologic disease" ;
rdfs:comment "Pathological processes of the ear, the nose, and the throat, also known as the ENT diseases." ;
rdfs:subClassOf obo:MONDO_7770006 .
obo:HP_0000925 a rdfs:Class ;
rdfs:label "Abnormality of the vertebral column" ;
rdfs:comment "Any abnormality of the vertebral column." ;
rdfs:subClassOf obo:HP_0009121 .
obo:MONDO_0005812 a rdfs:Class ;
rdfs:label "influenza" ;
rdfs:comment "An acute viral infection of the respiratory tract, occurring in isolated cases, in epidemics, or in pandemics; it is caused by serologically different strains of viruses (influenzaviruses) designated A, B, and C, has a 3-day incubation period, and usually lasts for 3 to 10 days. It is marked by inflammation of the nasal mucosa, pharynx, and conjunctiva; headache; myalgia; often fever, chills, and prostration; and occasionally involvement of the myocardium or central nervous system." ;
rdfs:subClassOf obo:MONDO_0024352 , obo:MONDO_0100329 .
obo:HP_0001510 a rdfs:Class ;
rdfs:label "Growth delay" ;
rdfs:comment "A deficiency or slowing down of growth pre- and postnatally." ;
rdfs:subClassOf obo:HP_0001507 .
obo:ECTO_9001631 a rdfs:Class ;
rdfs:label "exposure to metalloid" ;
rdfs:comment "An exposure to metalloid atom." ;
rdfs:subClassOf obo:ECTO_0000231 .
obo:MONDO_0016225 a rdfs:Class ;
rdfs:label "specific learning disability" ;
rdfs:comment "Diagnosed when there are specific deficits in an individualbs ability to perceive or process information efficiently and accurately. This disorder first manifests during the years of formal schooling and is characterized by persistent and impairing difficulties with learning foundational academic skills in reading, writing, and/or math. The individualbs performance of the affected academic skills is well below average for age, or acceptable performance levels are achieved only with extraordinary effort. Specific learning disorder may occur in individuals identified as intellectually gifted and manifest only when the learning demands or assessment procedures (e.g., timed tests) pose barriers that cannot be overcome by their innate intelligence and compensatory strategies. For all individuals, specific learning disorder can produce lifelong impairments in activities dependent on the skills, including occupational performance. (from dsm-V)" ;
rdfs:subClassOf obo:MONDO_0005071 .
obo:MONDO_0003778 a rdfs:Class ;
rdfs:label "inborn error of immunity" ;
rdfs:comment "A disorder in which the immune system is unable to mount an adequate immune response." ;
rdfs:subClassOf obo:MONDO_0005046 .
obo:ECTO_9001534 a rdfs:Class ;
rdfs:label "exposure to organochlorine insecticide" ;
rdfs:comment "An exposure to organochlorine insecticide." ;
rdfs:subClassOf obo:ECTO_9001535 .
obo:MONDO_0021100 a rdfs:Class ;
rdfs:label "breast neoplasm" ;
rdfs:comment "A benign or malignant neoplasm of the breast parenchyma. It can originate from the ducts, lobules or the breast adipose tissue. Breast neoplasms are much more common in females than males." ;
rdfs:subClassOf obo:MONDO_0002657 , obo:MONDO_0021350 .
obo:MONDO_0021682 a rdfs:Class ;
rdfs:label "viral sexually transmitted disease" ;
rdfs:comment "Viral diseases which are potentially transmitted or propagated by sexual conduct." ;
rdfs:subClassOf obo:MONDO_0021681 , obo:MONDO_0100329 .
obo:MONDO_0005414 a rdfs:Class ;
rdfs:label "treatment-refractory schizophrenia" ;
rdfs:comment "Schizophrenia which does not respond to commonly used treatments." ;
rdfs:subClassOf obo:MONDO_0005090 .
obo:MONDO_0005193 a rdfs:Class ;
rdfs:label "prostate intraepithelial neoplasia" ;
rdfs:comment "A neoplastic proliferation of the epithelial cells that line the acini and the ducts of the prostate gland. The neoplastic epithelial cells are confined within the acini and the ducts and they do not invade the surrounding prostatic stroma. Morphologically, it is classified as low or high grade." ;
rdfs:subClassOf obo:MONDO_0021259 , obo:MONDO_0024474 .
obo:MONDO_0005266 a rdfs:Class ;
rdfs:label "diabetic retinopathy" ;
rdfs:comment "A chronic, pathological complication associated with diabetes mellitus, where retinal damages are incurred due to microaneurysms in the vasculature of the retina, progressively leading to abnormal blood vessel growth, and swelling and leaking of fluid from blood vessels, resulting in vision loss or blindness." ;
rdfs:subClassOf obo:MONDO_0002311 , obo:MONDO_0005066 .
obo:ECTO_9000533 a rdfs:Class ;
rdfs:label "exposure to organofluorine compound" ;
rdfs:comment "An exposure to organofluorine compound." ;
rdfs:subClassOf obo:ECTO_0000135 , obo:ECTO_9001124 .
obo:HP_0020114 a rdfs:Class ;
rdfs:label "Persistent human papillomavirus infection" ;
rdfs:comment "Human papillomaviruses (HPVs) are small oncogenic viruses. HPV has been shown to cause a variety of lesions and malignancies, which predominantly affect the anogenital region. Low-risk, non-oncogenic HPV types are associated with anogenital warts and recurrent respiratory papillomatosis while high-risk, oncogenic types are associated with cervical, penile, anal, vaginal, vulvar, and oropharyngeal cancers. Infection with anogenital HPV is usually asymptomatic and resolves spontaneously without consequences in the immunocompetent host. When disease does occur, the most common manifestation is genital warts, which may be small papules, or flat, smooth or pedunculated lesions. This resolution of HPV lesions is not generally seen in the immunosuppressed, resulting in severe, persistent and extensive manifestations of HPV disease." ;
rdfs:subClassOf obo:HP_0032169 .
obo:HP_0031501 a rdfs:Class ;
rdfs:label "Pelvic mass" ;
rdfs:comment "An abnormal enlargement or swelling in the pelvic region." ;
rdfs:subClassOf obo:HP_0001438 .
obo:ECTO_8000019 a rdfs:Class ;
rdfs:label "exposure to environmental pollution" ;
rdfs:comment "A exposure event involving the interaction of an exposure receptor to environmental pollution." ;
rdfs:subClassOf obo:ECTO_8000000 .
obo:MONDO_0005053 a rdfs:Class ;
rdfs:label "ischemic disease" ;
rdfs:comment "Lack of blood supply to an area of the body, resulting in impairment of tissue oxygenation." ;
rdfs:subClassOf obo:MONDO_0005385 .
obo:MONDO_0021315 a rdfs:Class ;
rdfs:label "malignant tumor of nasopharynx" ;
rdfs:comment "A cancer that involves the nasopharynx." ;
rdfs:subClassOf obo:MONDO_0005375 , obo:MONDO_0005517 .
obo:MONDO_0021143 a rdfs:Class ;
rdfs:label "melanocytic neoplasm" ;
rdfs:subClassOf obo:MONDO_0005070 , obo:MONDO_0021635 .
obo:MONDO_0005815 a rdfs:Class ;
rdfs:label "pancreatic neuroendocrine neoplasm" ;
rdfs:comment "A neoplasm with neuroendocrine differentiation that arises from the pancreas. It includes neuroendocrine tumors (low and intermediate grade) and neuroendocrine carcinomas (high grade)." ;
rdfs:subClassOf obo:MONDO_0001933 , obo:MONDO_0021040 , obo:MONDO_0024503 .
obo:MONDO_0021069 a rdfs:Class ;
rdfs:label "malignant endocrine neoplasm" ;
rdfs:comment "A malignant neoplasm affecting the endocrine glands. Representative examples include thyroid gland carcinoma, parathyroid gland carcinoma, pituitary gland carcinoma, and adrenal cortex carcinoma." ;
rdfs:subClassOf obo:MONDO_0002082 , obo:MONDO_0004992 .
obo:MONDO_0005311 a rdfs:Class ;
rdfs:label "atherosclerosis" ;
rdfs:comment "A disease characterized by the build-up of fatty material and calcium deposition in the arterial wall resulting in partial or complete occlusion of the arterial lumen." ;
rdfs:subClassOf obo:MONDO_0002277 .
obo:HP_0004970 a rdfs:Class ;
rdfs:label "Ascending tubular aorta aneurysm" ;
rdfs:comment "An abnormal localized widening (dilatation) of the tubular part of the ascending aorta." ;
rdfs:subClassOf obo:HP_0012727 .
obo:ECTO_9001620 a rdfs:Class ;
rdfs:label "exposure to perfluorinated compound" ;
rdfs:comment "An exposure to perfluorinated compound." ;
rdfs:subClassOf obo:ECTO_9000533 .
obo:MONDO_0005300 a rdfs:Class ;
rdfs:label "chronic kidney disease" ;
rdfs:comment "Impairment of the renal function secondary to chronic kidney damage persisting for three or more months." ;
rdfs:subClassOf obo:MONDO_0005240 .
obo:ECTO_0900037 a rdfs:Class ;
rdfs:label "exposure to potassium via ingestion" ;
rdfs:comment "An exposure to potassium atom via ingestion route." ;
rdfs:subClassOf obo:ECTO_0000135 , obo:ECTO_0900042 .
obo:ECTO_9000010 a rdfs:Class ;
rdfs:label "exposure to estrogens" ;
rdfs:comment "An exposure to estrogen." ;
rdfs:subClassOf obo:ECTO_9002127 .
obo:HP_0004322 a rdfs:Class ;
rdfs:label "Short stature" ;
rdfs:comment "A height below that which is expected according to age and gender norms. Although there is no universally accepted definition of short stature, many refer to \"short stature\" as height more than 2 standard deviations below the mean for age and gender (or below the 3rd percentile for age and gender dependent norms)." ;
rdfs:subClassOf obo:HP_0000002 , obo:HP_0001510 .
obo:HP_0001622 a rdfs:Class ;
rdfs:label "Premature birth" ;
rdfs:comment "The birth of a baby of less than 37 weeks of gestational age." ;
rdfs:subClassOf obo:HP_0001197 .
obo:MONDO_0015254 a rdfs:Class ;
rdfs:label "schistosomiasis" ;
rdfs:comment "An infectious disease caused by parasitic trematodes of the genus Schistosoma that colonize human blood vessels and release eggs that can cause granulomatous reactions leading to acute (swimmer's itch or acute schistosomiasis syndrome) or chronic disease. Depending on where the eggs lodge, manifestations of chronic schistosomiasis can include diarrhea, abdominal pain, loss of appetite, anemia (intestines), hepatosplenism, periportal fibrosis with portal hypertension (liver), urogenital inflammation and scarring, hematuria and dysuria (genitourinary system). Other patients may be asymptomatic." ;
rdfs:subClassOf obo:MONDO_0004664 , obo:MONDO_0100120 .
obo:MONDO_0005113 a rdfs:Class ;
rdfs:label "bacterial infectious disease" ;
rdfs:comment "An acute infectious disorder that is caused by gram positive or gram negative bacteria; representative examples include pneumococcal, streptococcal, salmonella, and meningeal infections." ;
rdfs:subClassOf obo:MONDO_0005550 .
obo:MONDO_0006181 a rdfs:Class ;
rdfs:label "digestive system carcinoma" ;
rdfs:comment "A malignant neoplasm that arises from the epithelium of any part of the digestive system. Representative examples include colorectal carcinoma, esophageal carcinoma, and pancreatic carcinoma." ;
rdfs:subClassOf obo:MONDO_0002516 , obo:MONDO_0004993 .
obo:BFO_0000023 a rdfs:Class ;
rdfs:label "role"@en ;
rdfs:comment "A realizable entity the manifestation of which brings about some result or end that is not essential to a continuant in virtue of the kind of thing that it is but that can be served or participated in by that kind of continuant in some kinds of natural, social or institutional contexts."@en ;
rdfs:subClassOf obo:BFO_0000017 .
obo:MONDO_0005211 a rdfs:Class ;
rdfs:label "ovarian serous adenocarcinoma" ;
rdfs:comment "An adenocarcinoma that arises from the ovary and is characterized by the presence of malignant epithelial cells that, in well differentiated tumors, resemble the epithelium of the fallopian tube or, in poorly differentiated tumors, show anaplastic features and marked nuclear atypia." ;
rdfs:subClassOf obo:MONDO_0002752 , obo:MONDO_0005278 , obo:MONDO_0024885 .
obo:HP_0005115 a rdfs:Class ;
rdfs:label "Supraventricular arrhythmia" ;
rdfs:comment "A type of arrhythmia that originates above the ventricles, whereby the electrical impulse propagates down the normal His Purkinje system similar to normal sinus rhythm." ;
rdfs:subClassOf obo:HP_0011675 .
obo:MONDO_0005338 a rdfs:Class ;
rdfs:label "open-angle glaucoma" ;
rdfs:comment "Chronic outflow obstruction of the eye's drainage canals that can lead to increased internal eye pressure and optic nerve damage." ;
rdfs:subClassOf obo:MONDO_0005041 .
obo:MONDO_0004892 a rdfs:Class ;
rdfs:label "refractive error" ;
rdfs:comment "A defect in the focusing of light on the retina as in astigmatism, myopia, or hyperopia." ;
rdfs:subClassOf obo:MONDO_0005328 .
obo:MONDO_0019052 a rdfs:Class ;
rdfs:label "inborn errors of metabolism" ;
rdfs:comment "An inherited disorder resulting from an enzyme defect in biochemical and metabolic pathways affecting proteins, fats, carbohydrates metabolism or organelle function." ;
rdfs:subClassOf obo:MONDO_0003847 , obo:MONDO_0005066 .
obo:MONDO_0005391 a rdfs:Class ;
rdfs:label "restless legs syndrome" ;
rdfs:comment "A condition that occurs while resting or lying in bed; it is characterized by an irresistible urgency to move the legs to obtain relief from a strange and uncomfortable sensation in the legs." ;
rdfs:subClassOf obo:MONDO_0005071 .
obo:HP_0002617 a rdfs:Class ;
rdfs:label "Vascular dilatation" ;
rdfs:comment "An abnormal increase in the diameter of an artery or vein, either as a diffuse dilatation or as a localized, sac-like outpouching of the vessel wall (aneurysm)." ;
rdfs:subClassOf obo:HP_0033353 .
obo:MONDO_0005570 a rdfs:Class ;
rdfs:label "hematologic disorder" ;
rdfs:comment "A disease involving the hematopoietic system." ;
rdfs:subClassOf obo:MONDO_7770006 .
obo:MONDO_0003767 a rdfs:Class ;
rdfs:label "mitral valve disorder" ;
rdfs:comment "A disease involving the mitral valve." ;
rdfs:subClassOf obo:MONDO_0002869 .
obo:ECTO_0100013 a rdfs:Class ;
rdfs:label "exposure to tobacco" ;
rdfs:comment "An exposure event involving nicotine tobacco consumption" ;
rdfs:subClassOf obo:ExO_0000002 .
obo:MONDO_0004985 a rdfs:Class ;
rdfs:label "bipolar disorder" ;
rdfs:comment "A disorder of the brain that causes unusual shifts in mood, energy, activity levels and the ability to carry out day-to-day tasks. Often these moods range and shift from periods of elation and energized behavior to those of hopelessness and depression." ;
rdfs:subClassOf obo:MONDO_0005371 .
obo:IAO_8000002 a rdfs:Class ;
rdfs:label "editors ontology module"@en ;
rdfs:comment "An ontology module that is intended to be directly edited, typically managed in source control, and typically not intended for direct consumption by end-users."@en ;
rdfs:subClassOf obo:IAO_8000000 .
obo:IAO_8000017 a rdfs:Class ;
rdfs:label "ontology module subsetted by expressivity"@en ;
rdfs:subClassOf obo:IAO_8000006 .
obo:MONDO_0006993 a rdfs:Class ;
rdfs:label "systolic heart failure" ;
rdfs:comment "Heart failure caused by abnormal myocardial contraction during systole leading to defective cardiac emptying." ;
rdfs:subClassOf obo:MONDO_0005009 .
obo:MONDO_0002546 a rdfs:Class ;
rdfs:label "schwannoma" ;
rdfs:comment "A benign, usually encapsulated slow growing tumor composed of Schwann cells. It affects peripheral and cranial nerves. It recurs infrequently and only rare cases associated with malignant transformation have been reported." ;
rdfs:subClassOf obo:MONDO_0002547 , obo:MONDO_0016752 , obo:MONDO_0021637 .
obo:ECTO_9000033 a rdfs:Class ;
rdfs:label "exposure to asbestos" ;
rdfs:comment "An exposure to asbestos." ;
rdfs:subClassOf obo:ECTO_0000231 .
obo:MONDO_0002352 a rdfs:Class ;
rdfs:label "larynx cancer" ;
rdfs:comment "A primary or metastatic malignant neoplasm involving the larynx. The majority are carcinomas." ;
rdfs:subClassOf obo:MONDO_0000376 , obo:MONDO_0021071 .
obo:MONDO_0005628 a rdfs:Class ;
rdfs:label "male breast carcinoma" ;
rdfs:comment "A malignant neoplasm involving the male breast." ;
rdfs:subClassOf obo:MONDO_0004989 .
obo:HP_0004377 a rdfs:Class ;
rdfs:label "Hematological neoplasm" ;
rdfs:comment "Neoplasms located in the blood and blood-forming tissue (the bone marrow and lymphatic tissue)." ;
rdfs:subClassOf obo:HP_0001871 , obo:HP_0011793 .
obo:ECTO_0000015 a rdfs:Class ;
rdfs:label "exposure to environmental material" ;
rdfs:comment "A exposure event involving the interaction of an exposure receptor to environmental material." ;
rdfs:subClassOf obo:ExO_0000002 .
obo:MONDO_0800486 a rdfs:Class ;
rdfs:label "metabolic bone disorder" ;
rdfs:comment "A group of disorders that affect the bones secondary to increased levels of minerals or deficient levels of minerals such as calcium, magnesium, phosphorus, and vitamin D. Representative examples are osteomalacia, osteoporosis, and Paget disease." ;
rdfs:subClassOf obo:MONDO_0005381 .
obo:MONDO_0006345 a rdfs:Class ;
rdfs:label "palmar fibromatosis" ;
rdfs:comment "A superficial fibromatosis arising from the soft tissue of the palm. It is characterized by the presence of spindle-shaped fibroblasts, and an infiltrative growth pattern. It predominantly affects adult males." ;
rdfs:subClassOf obo:MONDO_0016037 .
obo:HP_0025142 a rdfs:Class ;
rdfs:label "Constitutional symptom" ;
rdfs:comment "A symptom or manifestation indicating a systemic or general effect of a disease and that may affect the general well-being or status of an individual." ;
rdfs:subClassOf obo:HP_0000118 .
obo:HP_0001297 a rdfs:Class ;
rdfs:label "Stroke" ;
rdfs:comment "Sudden impairment of blood flow to a part of the brain due to occlusion or rupture of an artery to the brain." ;
rdfs:subClassOf obo:HP_0100659 .
obo:HP_0410324 a rdfs:Class ;
rdfs:label "Dust mite allergy" ;
rdfs:comment "Hypersensitivity in form of an adverse immune reaction against dust mites." ;
rdfs:subClassOf obo:HP_0012393 .
obo:MONDO_0008903 a rdfs:Class ;
rdfs:label "lung cancer" ;
rdfs:comment "A malignant neoplasm involving the lung." ;
rdfs:subClassOf obo:MONDO_0000376 , obo:MONDO_0003274 , obo:MONDO_0021117 .
obo:MONDO_0005530 a rdfs:Class ;
rdfs:label "opiate dependence" ;
rdfs:comment "Disorders related or resulting from abuse or mis-use of opioids." ;
rdfs:subClassOf obo:MONDO_0005303 .
obo:MONDO_0004994 a rdfs:Class ;
rdfs:label "cardiomyopathy" ;
rdfs:comment "A disease of the heart muscle or myocardium proper. Cardiomyopathies may be classified as either primary or secondary, on the basis of etiology, or on the pathophysiology of the lesion: hypertrophic, dilated, or restrictive." ;
rdfs:subClassOf obo:MONDO_0003939 , obo:MONDO_0005267 .
obo:MONDO_0018076 a rdfs:Class ;
rdfs:label "tuberculosis" ;
rdfs:comment "A chronic, recurrent infection caused by the bacterium Mycobacterium tuberculosis. Tuberculosis (TB) may affect almost any tissue or organ of the body with the lungs being the most common site of infection. The clinical stages of TB are primary or initial infection, latent or dormant infection, and recrudescent or adult-type TB. Ninety to 95% of primary TB infections may go unrecognized. Histopathologically, tissue lesions consist of granulomas which usually undergo central caseation necrosis. Local symptoms of TB vary according to the part affected; acute symptoms include hectic fever, sweats, and emaciation; serious complications include granulomatous erosion of pulmonary bronchi associated with hemoptysis. If untreated, progressive TB may be associated with a high degree of mortality. This infection is frequently observed in immunocompromised individuals with AIDS or a history of illicit IV drug use." ;
rdfs:subClassOf obo:MONDO_0000314 , obo:MONDO_0020590 .
obo:MONDO_0006047 a rdfs:Class ;
rdfs:label "pancreatic adenocarcinoma" ;
rdfs:comment "A carcinoma that arises from glandular epithelial cells of the pancreas" ;
rdfs:subClassOf obo:MONDO_0004970 , obo:MONDO_0005192 .
obo:MONDO_0000931 a rdfs:Class ;
rdfs:label "endometrial disorder" ;
rdfs:comment "A non-neoplastic or neoplastic disorder that affects the endometrium. Representative examples include endometritis, endometrial hyperplasia, and endometrial carcinoma." ;
rdfs:subClassOf obo:MONDO_0002654 .
obo:MONDO_0006424 a rdfs:Class ;
rdfs:label "soft tissue neoplasm" ;
rdfs:comment "A benign, intermediate, or malignant neoplasm that arises from the soft tissue. The most common types are lipomatous (fatty), vascular, smooth muscle, fibrous, and fibrohistiocytic neoplasms." ;
rdfs:subClassOf obo:MONDO_0044334 .
obo:GO_0008150 a rdfs:Class ;
rdfs:label "biological_process" ;
rdfs:comment "A biological process is the execution of a genetically-encoded biological module or program. It consists of all the steps required to achieve the specific biological objective of the module. A biological process is accomplished by a particular set of molecular functions carried out by specific gene products (or macromolecular complexes), often in a highly regulated manner and in a particular temporal sequence." ;
rdfs:subClassOf obo:BFO_0000015 .
obo:ECTO_9000205 a rdfs:Class ;
rdfs:label "exposure to caffeine" ;
rdfs:comment "An exposure to caffeine." ;
rdfs:subClassOf obo:ECTO_9000202 , obo:ECTO_9000271 .
obo:MONDO_0021637 a rdfs:Class ;
rdfs:label "low grade glioma" ;
rdfs:comment "A grade I or grade II glioma arising from the central nervous system. This category includes pilocytic astrocytoma, diffuse astrocytoma, subependymal giant cell astrocytoma, ependymoma, oligodendroglioma, oligoastrocytoma, and angiocentric glioma." ;
rdfs:subClassOf obo:MONDO_0021042 .
obo:HP_0006704 a rdfs:Class ;
rdfs:label "Abnormal coronary artery morphology" ;
rdfs:comment "Any structural abnormality of the coronary arteries." ;
rdfs:subClassOf obo:HP_0011004 .
obo:HP_0002087 a rdfs:Class ;
rdfs:label "Abnormality of the upper respiratory tract" ;
rdfs:comment "An abnormality of the upper respiratory tract." ;
rdfs:subClassOf obo:HP_0012252 .
obo:IAO_8000013 a rdfs:Class ;
rdfs:label "reasoned ontology module"@en ;
rdfs:comment "An ontology module that contains axioms generated by a reasoner. The generated axioms are typically direct SubClassOf axioms, but other possibilities are available."@en ;
rdfs:seeAlso ;
rdfs:subClassOf obo:IAO_8000000 .
obo:MONDO_0019056 a rdfs:Class ;
rdfs:label "neuromuscular disease" ;
rdfs:comment "Any disease that impairs the functioning of the muscles, either directly, being pathologies of the voluntary muscle, or indirectly, being pathologies of nerves or neuromuscular junctions." ;
rdfs:subClassOf obo:MONDO_0005071 .
obo:BFO_0000016 a rdfs:Class ;
rdfs:label "disposition"@en ;
rdfs:subClassOf obo:BFO_0000017 .
obo:ECTO_7000033 a rdfs:Class ;
rdfs:label "exposure to dust from plant parts" ;
rdfs:comment "A exposure event involving the interaction of an exposure receptor to dust from plant parts." ;
rdfs:subClassOf obo:ECTO_7000001 .
obo:MONDO_0005165 a rdfs:Class ;
rdfs:label "benign neoplasm" ;
rdfs:comment "A neoplasm which is characterized by the absence of morphologic features associated with malignancy (severe cytologic atypia, tumor cell necrosis, and high mitotic rate). Benign neoplasms remain confined to the original site of growth and do not metastasize to other anatomic sites." ;
rdfs:subClassOf obo:MONDO_0005070 .
obo:MONDO_0012038 a rdfs:Class ;
rdfs:label "speech-sound disorder" ;
rdfs:subClassOf obo:MONDO_0003847 .
obo:HP_0025423 a rdfs:Class ;
rdfs:label "Abnormal larynx morphology" ;
rdfs:comment "Any anomaly of the structure of the larynx." ;
rdfs:subClassOf obo:HP_0001600 .
obo:ECTO_0900047 a rdfs:Class ;
rdfs:label "exposure to allergen via inhalation" ;
rdfs:comment "An exposure to allergen via inhalation route." ;
rdfs:subClassOf obo:ECTO_0000726 .
obo:MONDO_0005786 a rdfs:Class ;
rdfs:label "Hepadnaviridae infectious disease" ;
rdfs:comment "Virus diseases caused by the hepadnaviridae." ;
rdfs:subClassOf obo:MONDO_0100329 .
obo:ECTO_7000026 a rdfs:Class ;
rdfs:label "exposure to cement dust" ;
rdfs:comment "A exposure event involving the interaction of an exposure receptor to cement dust." ;
rdfs:subClassOf obo:ECTO_7000001 .
obo:HP_0001695 a rdfs:Class ;
rdfs:label "Cardiac arrest" ;
rdfs:comment "An abrupt loss of heart function." ;
rdfs:subClassOf obo:HP_0011675 .
obo:HP_0000707 a rdfs:Class ;
rdfs:label "Abnormality of the nervous system" ;
rdfs:comment "An abnormality of the nervous system." ;
rdfs:subClassOf obo:HP_0000118 .
obo:MONDO_0004658 a rdfs:Class ;
rdfs:label "breast carcinoma in situ" ;
rdfs:comment "A in situ carcinoma that involves the breast." ;
rdfs:subClassOf obo:MONDO_0004647 , obo:MONDO_0004989 .
obo:MONDO_0003182 a rdfs:Class ;
rdfs:label "anterior horn disorder" ;
rdfs:comment "Anterior horn disease is one of a number of medical disorders affecting the anterior horn of the spinal cord. Anterior horn diseases include spinal muscular atrophy, poliomyelitis and amyotrophic lateral sclerosis." ;
rdfs:subClassOf obo:MONDO_0002545 .
obo:MONDO_0021246 a rdfs:Class ;
rdfs:label "pharynx neoplasm" ;
rdfs:comment "A neoplasm (disease) that involves the pharynx." ;
rdfs:subClassOf obo:MONDO_0021223 .
obo:MONDO_1060200 a rdfs:Class ;
rdfs:label "primary hyperthyroidism" ;
rdfs:comment "A form of hyperthyroidism caused by overproduction of thyroid hormones (T3 and T4) due to pathology within the thyroid gland itself. Primary hyperthyroidism is characterized by low TSH levels and elevated T3/T4 levels." ;
rdfs:subClassOf obo:MONDO_0004425 .
obo:NCIT_C20181 a rdfs:Class ;
rdfs:label "Conceptual Entity" .
obo:MONDO_0800504 a rdfs:Class ;
rdfs:label "idiopathic pulmonary fibrosis" ;
rdfs:comment "An interstitial lung disease with a poor prognosis, that is characterized by the progressive formation of scar tissue within the lungs in the absence of any known cause." ;
rdfs:subClassOf obo:MONDO_0002429 , obo:MONDO_0015925 .
obo:MONDO_0005277 a rdfs:Class ;
rdfs:label "migraine disorder" ;
rdfs:comment "A common, severe type of vascular headache often associated with increased sympathetic activity, resulting in nausea, vomiting, and light sensitivity." ;
rdfs:subClassOf obo:MONDO_0005560 , obo:MONDO_0017181 , obo:MONDO_0043218 .
obo:MONDO_0021223 a rdfs:Class ;
rdfs:label "digestive system neoplasm" ;
rdfs:comment "A neoplasm (disease) that involves the digestive system." ;
rdfs:subClassOf obo:MONDO_0005070 .
obo:HP_0002977 a rdfs:Class ;
rdfs:label "Aplasia/Hypoplasia involving the central nervous system" ;
rdfs:comment "Absence or underdevelopment of tissue in the central nervous system." ;
rdfs:subClassOf obo:HP_0002011 .
obo:GO_0003674 a rdfs:Class ;
rdfs:label "molecular_function" ;
rdfs:comment "A molecular process that can be carried out by the action of a single macromolecular machine, usually via direct physical interactions with other molecular entities. Function in this sense denotes an action, or activity, that a gene product (or a complex) performs." ;
rdfs:subClassOf obo:BFO_0000015 .
obo:MONDO_0019722 a rdfs:Class ;
rdfs:label "glomerular disorder" ;
rdfs:comment "A disease involving the renal glomerulus." ;
rdfs:subClassOf obo:MONDO_0005240 .
obo:MONDO_0005439 a rdfs:Class ;
rdfs:label "familial hypercholesterolemia" ;
rdfs:comment "An inheritable form of hyperlipidemia, in which there are excess lipids in the blood." ;
rdfs:subClassOf obo:MONDO_0001336 , obo:MONDO_0037748 .
obo:MONDO_0024331 a rdfs:Class ;
rdfs:label "colorectal carcinoma" ;
rdfs:comment "A malignant epithelial neoplasm that arises from the colon or rectum and invades through the muscularis mucosa into the submucosa. The vast majority are adenocarcinomas." ;
rdfs:subClassOf obo:MONDO_0005575 , obo:MONDO_0006181 .
obo:MONDO_0006519 a rdfs:Class ;
rdfs:label "rectal cancer" ;
rdfs:comment "A primary or metastatic malignant neoplasm that affects the rectum. Representative examples include carcinoma, lymphoma, and sarcoma." ;
rdfs:subClassOf obo:MONDO_0002165 , obo:MONDO_0005575 .
obo:HP_0025722 a rdfs:Class ;
rdfs:label "Cerebral infarct" ;
rdfs:comment "A necrotic lesion in the cerebrum resulting from a sudden insufficiency of arterial or venous blood supply due to emboli, thrombi or mechanical factors." ;
rdfs:subClassOf obo:HP_0002060 .
obo:MONDO_0005580 a rdfs:Class ;
rdfs:label "esophageal squamous cell carcinoma" ;
rdfs:comment "Esophageal squamous cell carcinoma (ESCC) is a type of esophageal carcinoma (EC) that can affect any part of the esophagus, but is usually located in the upper or middle third." ;
rdfs:subClassOf obo:MONDO_0005096 , obo:MONDO_0019086 .
obo:HP_0012443 a rdfs:Class ;
rdfs:label "Abnormal brain morphology" ;
rdfs:comment "A structural abnormality of the brain, which has as its parts the forebrain, midbrain, and hindbrain." ;
rdfs:subClassOf obo:HP_0002011 .
obo:ECTO_6000015 a rdfs:Class ;
rdfs:label "exposure to lifestyle" ;
rdfs:comment "An exposure event involving Lifestyle" ;
rdfs:subClassOf obo:ECTO_6000000 .
obo:MONDO_0006644 a rdfs:Class ;
rdfs:label "alcoholic liver cirrhosis" ;
rdfs:comment "A disorder of the liver characterized by the presence of fibrotic scar tissue instead of healthy liver tissue. This condition is attributed to excessive consumption of alcoholic beverages." ;
rdfs:subClassOf obo:MONDO_0005155 , obo:MONDO_0043693 .
obo:ECTO_0000486 a rdfs:Class ;
rdfs:label "exposure to chemical with application" ;
rdfs:comment "An exposure to application." ;
rdfs:subClassOf obo:ExO_0000002 .
obo:MONDO_0021147 a rdfs:Class ;
rdfs:label "disorder of development or morphogenesis" ;
rdfs:comment "Any disease or disorder that disrupts the process development of an anatomical structure. Can be due to genetic or environmental causes. Typically happens during embryogenesis, but also includes post-embryonic development." ;
rdfs:subClassOf obo:MONDO_7770007 .
obo:MONDO_0018872 a rdfs:Class ;
rdfs:label "acute megakaryoblastic leukemia" ;
rdfs:comment "Acute megakaryoblastic leukemia (AMKL) is a form of acute myeloid leukemia (AML) that occurs predominantly in childhood and particularly in children with Down syndrome (DS-AMKL). Nonspecific symptoms may be irritability, weakness, and dizziness while specific symptoms include pallor, fever, mucocutaneous bleeding, hepatosplenomegaly, neurological manifestations and rarely lymphadenopathy. Acute panmyelosis with myelofibrosis may also be associated with AMKL. In contrast to DS-AMKL (around 80 % survival), non-DS-AMKL is an AML subgroup associated with poor prognosis." ;
rdfs:subClassOf obo:MONDO_0015667 .
obo:MONDO_0005161 a rdfs:Class ;
rdfs:label "human papilloma virus infection" ;
rdfs:comment "An infectious process caused by a human papillomavirus. This infection can cause abnormal tissue growth." ;
rdfs:subClassOf obo:MONDO_0100329 .
obo:HP_0003011 a rdfs:Class ;
rdfs:label "Abnormality of the musculature" ;
rdfs:comment "Abnormality originating in one or more muscles, i.e., of the set of muscles of body." ;
rdfs:subClassOf obo:HP_0033127 .
obo:MONDO_0021253 a rdfs:Class ;
rdfs:label "gallbladder neoplasm" ;
rdfs:comment "A neoplasm (disease) that involves the gall bladder." ;
rdfs:subClassOf obo:MONDO_0002514 , obo:MONDO_0005281 .
obo:ECTO_7000116 a rdfs:Class ;
rdfs:label "exposure to respirable suspended particulate matter" ;
rdfs:comment "A exposure event involving the interaction of an exposure receptor to respirable suspended particulate matter." ;
rdfs:subClassOf obo:ECTO_7000114 .
obo:MONDO_0005485 a rdfs:Class ;
rdfs:label "psychotic disorder" ;
rdfs:comment "An abnormal condition of the mind that involves a loss of contact with reality. People experiencing psychosis may exhibit personality changes and thought disorder. Depending on its severity, this may be accompanied by unusual or bizarre behavior, as well as difficulty with social interaction and impairment in carrying out daily life activities." ;
rdfs:subClassOf obo:MONDO_0002039 , obo:MONDO_0005084 .
obo:ECTO_9000026 a rdfs:Class ;
rdfs:label "exposure to alcohol" ;
rdfs:comment "An exposure to alcohol." ;
rdfs:subClassOf obo:ECTO_0000135 , obo:ECTO_0000371 .
obo:MONDO_7770006 a rdfs:Class ;
rdfs:label "disease by body system or component" ;
rdfs:comment "A grouping class for human diseases classified by the body system or anatomical component primarily affected." ;
rdfs:subClassOf obo:MONDO_0700096 .
obo:MONDO_0008575 a rdfs:Class ;
rdfs:label "nicotine dependence" ;
rdfs:comment "Physical and psychological dependence on nicotine." ;
rdfs:subClassOf obo:MONDO_0005303 .
obo:MONDO_0005367 a rdfs:Class ;
rdfs:label "heroin dependence" ;
rdfs:comment "Physical and psychological dependence on the drug heroin." ;
rdfs:subClassOf obo:MONDO_0005530 .
obo:MONDO_0008171 a rdfs:Class ;
rdfs:label "nephrolithiasis" ;
rdfs:comment "The presence of a calculus in the pelvis of the kidney; this is most often composed of mineral salts and proteins." ;
rdfs:subClassOf obo:MONDO_0005240 , obo:MONDO_0024647 .
obo:MONDO_0004989 a rdfs:Class ;
rdfs:label "breast carcinoma" ;
rdfs:comment "A carcinoma that arises from epithelial cells of the breast" ;
rdfs:subClassOf obo:MONDO_0004993 , obo:MONDO_0007254 .
obo:MONDO_0004298 a rdfs:Class ;
rdfs:label "stomach disorder" ;
rdfs:comment "A disease involving the stomach." ;
rdfs:subClassOf obo:MONDO_0004335 .
obo:HP_0025015 a rdfs:Class ;
rdfs:label "Abnormal vascular morphology" ;
rdfs:subClassOf obo:HP_0002597 , obo:HP_0030680 .
obo:MONDO_0004730 a rdfs:Class ;
rdfs:label "speech disorder" ;
rdfs:comment "A term referring to disorders characterized by the disruption of normal speech. It includes stuttering, lisps, dysarthria and voice disorders." ;
rdfs:subClassOf obo:MONDO_0002182 .
obo:ECTO_9002766 a rdfs:Class ;
rdfs:label "exposure to omega-3 fatty acid" ;
rdfs:comment "An exposure to omega-3 fatty acid." ;
rdfs:subClassOf obo:ECTO_9002507 .
obo:MONDO_0000589 a rdfs:Class ;
rdfs:label "autoimmune disorder of musculoskeletal system" ;
rdfs:comment "A hypersensitivity reaction type II disease that involves the musculoskeletal system." ;
rdfs:subClassOf obo:MONDO_0002081 , obo:MONDO_0007179 .
obo:MONDO_0017595 a rdfs:Class ;
rdfs:label "aggressive B-cell non-Hodgkin lymphoma" ;
rdfs:subClassOf obo:MONDO_0015759 .
obo:MONDO_0043218 a rdfs:Class ;
rdfs:label "neurovascular disorder" ;
rdfs:comment "A disorder of the nervous system related to a vascular etiology." ;
rdfs:subClassOf obo:MONDO_0005071 , obo:MONDO_0005385 .
obo:IAO_0000030 a rdfs:Class ;
rdfs:label "information content entity"@en .
obo:MONDO_0005574 a rdfs:Class ;
rdfs:label "tauopathy" ;
rdfs:comment "Neurodegenerative disorders involving deposition of abnormal tau protein isoforms (tau proteins) in neurons and glial cells in the brain. Pathological aggregations of tau proteins are associated with mutation of the tau gene on chromosome 17 in patients with alzheimer disease; dementia; parkinsonian disorders; progressive supranuclear palsy (supranuclear palsy, progressive); and corticobasal degeneration." ;
rdfs:subClassOf obo:MONDO_0005559 , obo:MONDO_7770011 .
obo:MONDO_0019516 a rdfs:Class ;
rdfs:label "exudative vitreoretinopathy" ;
rdfs:comment "Familial exudative vitreoretinopathy (FEVR) is a rare hereditary vitreoretinal disorder characterized by abnormal or incomplete vascularization of the peripheral retina leading to variable clinical manifestations ranging from no effects to minor anomalies, or even retinal detachment with blindness." ;
rdfs:subClassOf obo:MONDO_0002311 , obo:MONDO_0020248 .
obo:MONDO_0021350 a rdfs:Class ;
rdfs:label "neoplasm of thorax" ;
rdfs:comment "A neoplasm (disease) that involves the thoracic segment of trunk." ;
rdfs:subClassOf obo:MONDO_0005070 .
obo:MONDO_0019467 a rdfs:Class ;
rdfs:label "CD4+/CD56+ hematodermic neoplasm" ;
rdfs:comment "An aggressive immature hematologic neoplasm formerly known as blastic NK cell lymphoma, composed of cells with a lymphoblast-like morphology. Recent evidence suggests derivation from a plasmacytoid monocyte. Patients present with cutaneous tumors and bone marrow involvement." ;
rdfs:subClassOf obo:MONDO_0002898 , obo:MONDO_0005170 , obo:MONDO_0015760 .
obo:ECTO_0010000 a rdfs:Class ;
rdfs:label "exposure to environmental quality" ;
rdfs:comment "A exposure event involving the interaction of an exposure receptor to quality." ;
rdfs:subClassOf obo:ExO_0000002 .
obo:ECTO_9000044 a rdfs:Class ;
rdfs:label "exposure to ketone" ;
rdfs:comment "An exposure to ketone." ;
rdfs:subClassOf obo:ECTO_0000135 , obo:ECTO_0000371 .
obo:ECTO_9002845 a rdfs:Class ;
rdfs:label "exposure to vitamin B3" ;
rdfs:comment "An exposure to vitamin B3." ;
rdfs:subClassOf obo:ECTO_9002026 .
obo:MONDO_0045024 a rdfs:Class ;
rdfs:label "cancer or benign tumor" ;
rdfs:comment "Any disorder that features disrupted cell proliferation. Includes hyperplasia, neoplastic syndrome and isolated neoplasm diseases as well as precancerous conditions." ;
rdfs:subClassOf obo:MONDO_7770008 .
obo:ECTO_8000008 a rdfs:Class ;
rdfs:label "exposure to climate change" ;
rdfs:comment "A exposure event involving the interaction of an exposure receptor to climate change." ;
rdfs:subClassOf obo:ECTO_8000000 .
obo:HP_0004416 a rdfs:Class ;
rdfs:label "Precocious atherosclerosis" ;
rdfs:subClassOf obo:HP_0002621 .
obo:IAO_8000006 a rdfs:Class ;
rdfs:label "subset ontology module"@en ;
rdfs:comment "An ontology module that is extracted from a main ontology module and includes only a subset of entities or axioms."@en ;
rdfs:seeAlso , ;
rdfs:subClassOf obo:IAO_8000000 .
obo:ECTO_9000946 a rdfs:Class ;
rdfs:label "exposure to manganese" ;
rdfs:comment "An exposure to manganese molecular entity." ;
rdfs:subClassOf obo:ECTO_0000481 .
obo:HP_0004936 a rdfs:Class ;
rdfs:label "Venous thrombosis" ;
rdfs:comment "Formation of a blood clot (thrombus) inside a vein, causing the obstruction of blood flow." ;
rdfs:subClassOf obo:HP_0001977 .
obo:MONDO_0003939 a rdfs:Class ;
rdfs:label "muscle tissue disorder" ;
rdfs:comment "A disease involving the muscle tissue." ;
rdfs:subClassOf obo:MONDO_0002081 .
obo:MONDO_0003150 a rdfs:Class ;
rdfs:label "male reproductive system disorder" ;
rdfs:comment "A disease involving the male reproductive system." ;
rdfs:subClassOf obo:MONDO_0005039 .
obo:MONDO_0005204 a rdfs:Class ;
rdfs:label "primary antiphospholipid syndrome" ;
rdfs:comment "An antiphospholipid syndrome that occurs as an isolated disorder." ;
rdfs:subClassOf obo:MONDO_8000010 .
obo:MONDO_0021193 a rdfs:Class ;
rdfs:label "neuroepithelial neoplasm" ;
rdfs:comment "A neoplasm of the nervous system that arises from the neuroepithelial tissues. Representative examples include astrocytic tumors, oligodendroglial tumors, ependymal tumors, and primitive neuroectodermal tumors." ;
rdfs:subClassOf obo:MONDO_0021248 .
obo:ECTO_9000252 a rdfs:Class ;
rdfs:label "exposure to nitrogen dioxide" ;
rdfs:comment "An exposure to nitrogen dioxide." ;
rdfs:subClassOf obo:ECTO_0000371 , obo:ECTO_9000172 , obo:ECTO_9000404 .
obo:MONDO_0021945 a rdfs:Class ;
rdfs:label "hearing disorder" ;
rdfs:comment "A disorder characterized by the partial or complete loss of the ability to detect sounds due to damage to the ear structures or inability of the brain to properly interpret or process the auditory signals it receives from the anatomic structures of the ear." ;
rdfs:subClassOf obo:MONDO_0002409 .
obo:MONDO_0017342 a rdfs:Class ;
rdfs:label "Epstein-Barr virus-related tumor" ;
rdfs:subClassOf obo:MONDO_0017341 .
obo:MONDO_0002158 a rdfs:Class ;
rdfs:label "fallopian tube cancer" ;
rdfs:comment "A primary or metastatic malignant neoplasm that affects the fallopian tube. Representative examples include carcinoma, carcinosarcoma, and leiomyosarcoma." ;
rdfs:subClassOf obo:MONDO_0001416 , obo:MONDO_0021092 .
obo:ECTO_0070232 a rdfs:Class ;
rdfs:label "exposure to vegetable food product via ingestion" ;
rdfs:comment "An exposure to vegetable food product via ingestion." ;
rdfs:subClassOf obo:ECTO_0000015 .
obo:ECTO_0100005 a rdfs:Class ;
rdfs:label "exposure to cannabis" ;
rdfs:comment "An exposure event involving Cannabis sativa consumption of an addictive substance" ;
rdfs:subClassOf obo:ExO_0000002 .
obo:MONDO_0002494 a rdfs:Class ;
rdfs:label "substance-related disorder" ;
rdfs:comment "A category of psychiatric disorders which include disorders related to the taking of a drug of abuse (including alcohol, prescribed medications and recreational drugs)." ;
rdfs:subClassOf obo:MONDO_0002025 .
obo:ECTO_0900042 a rdfs:Class ;
rdfs:label "exposure to chemical entity via ingestion" ;
rdfs:comment "An exposure to chemical entity via ingestion route." ;
rdfs:subClassOf obo:ECTO_0000231 .
obo:ECTO_0100002 a rdfs:Class ;
rdfs:label "exposure to smoking nicotine" ;
rdfs:comment "An exposure event involving nicotine smoking behavior" ;
rdfs:subClassOf obo:ExO_0000002 .
obo:MONDO_0002908 a rdfs:Class ;
rdfs:label "glucose metabolism disease" ;
rdfs:comment "A metabolic disorder characterized by abnormal blood glucose levels." ;
rdfs:subClassOf obo:MONDO_0005066 .
obo:MONDO_0002251 a rdfs:Class ;
rdfs:label "hepatitis" ;
rdfs:comment "An active inflammatory process affecting the liver for more than six months. Causes include viral infections, autoimmune disorders, drugs, and metabolic disorders." ;
rdfs:subClassOf obo:MONDO_0005154 , obo:MONDO_0021166 .
obo:MONDO_0005046 a rdfs:Class ;
rdfs:label "immune system disorder" ;
rdfs:comment "A disorder resulting from an abnormality in the immune system." ;
rdfs:subClassOf obo:MONDO_7770006 .
obo:MONDO_0020804 a rdfs:Class ;
rdfs:label "basal cell carcinoma" ;
rdfs:comment "A carcinoma involving the basal cells." ;
rdfs:subClassOf obo:MONDO_0004993 , obo:MONDO_0020799 .
obo:MONDO_0009807 a rdfs:Class ;
rdfs:label "osteosarcoma" ;
rdfs:comment "A usually aggressive malignant bone-forming mesenchymal neoplasm, predominantly affecting adolescents and young adults. It usually involves bones and less frequently extraosseous sites. It often involves the long bones (particularly distal femur, proximal tibia, and proximal humerus). Pain with or without a palpable mass is the most frequent clinical symptom. It may spread to other anatomic sites, particularly the lungs." ;
rdfs:subClassOf obo:MONDO_0005089 .
obo:MONDO_0002113 a rdfs:Class ;
rdfs:label "peritoneal carcinoma" ;
rdfs:comment "A peritoneum cancer that is located in the inside of the abdomen." ;
rdfs:subClassOf obo:MONDO_0002087 , obo:MONDO_0004993 .
obo:MONDO_0700328 a rdfs:Class ;
rdfs:label "podocytopathy" ;
rdfs:comment "A glomerular disorder caused by the structural or functional impairment of podocytes, which leads to proteinuria and often nephrotic syndrome." ;
rdfs:subClassOf obo:MONDO_0019722 .
obo:MONDO_0001106 a rdfs:Class ;
rdfs:label "kidney failure" ;
rdfs:comment "An acute or chronic condition that is characterized by the inability of the kidneys to adequately filter the blood." ;
rdfs:subClassOf obo:MONDO_0005240 .
obo:HP_0100547 a rdfs:Class ;
rdfs:label "Abnormal forebrain morphology" ;
rdfs:comment "An abnormality of the forebrain, which has as its parts the telencephalon, diencephalon, lateral ventricles and third ventricle." ;
rdfs:subClassOf obo:HP_0012443 .
obo:BFO_0000001 a rdfs:Class ;
rdfs:label "entity"@en .
obo:MONDO_0002616 a rdfs:Class ;
rdfs:label "mesenchymal cell neoplasm" ;
rdfs:comment "A benign, intermediate, or malignant neoplasm that arises from the mesenchyma-derived cells of the soft tissue or bone. Representative examples include lipoma, leiomyoma, leiomyosarcoma and osteosarcoma." ;
rdfs:subClassOf obo:MONDO_0005070 .
obo:HP_0025780 a rdfs:Class ;
rdfs:label "Abnormal volitional state" ;
rdfs:comment "An abnormality of internal states of motivation or drive that compromise, or interfere with, the ability of the person to attend to basic personal, social, or vocational activities." ;
rdfs:subClassOf obo:HP_0025766 .
obo:MONDO_0002654 a rdfs:Class ;
rdfs:label "uterine disorder" ;
rdfs:comment "A non-neoplastic or neoplastic disorder that affects the uterine corpus or the cervix. Representative examples of non-neoplastic disorders include endometritis and cervicitis. Representative examples of neoplastic disorders include endometrial carcinoma, carcinosarcoma, and cervical carcinoma." ;
rdfs:subClassOf obo:MONDO_0002263 .
obo:HP_0012393 a rdfs:Class ;
rdfs:label "Allergy" ;
rdfs:comment "An allergy is an immune response or reaction to substances that are usually not harmful." ;
rdfs:subClassOf obo:HP_0100326 .
obo:MONDO_0001531 a rdfs:Class ;
rdfs:label "blood coagulation disease" ;
rdfs:comment "A condition in which there is a deviation from or interruption of the normal coagulation properties of the blood." ;
rdfs:subClassOf obo:MONDO_0005570 .
obo:ECTO_9000202 a rdfs:Class ;
rdfs:label "exposure to purines" ;
rdfs:comment "An exposure to purines." ;
rdfs:subClassOf obo:ECTO_0000163 , obo:ECTO_9000190 .
obo:MONDO_0002039 a rdfs:Class ;
rdfs:label "cognitive disorder" ;
rdfs:comment "A disease affects cognitive processes." ;
rdfs:subClassOf obo:MONDO_0002025 .
obo:MONDO_0600023 a rdfs:Class ;
rdfs:label "idiopathic inflammatory myopathy" ;
rdfs:comment "Idiopathic form of inflammatory myopathy." ;
rdfs:subClassOf obo:MONDO_0021167 .
obo:MONDO_0003569 a rdfs:Class ;
rdfs:label "cranial nerve neuropathy" ;
rdfs:comment "A neoplastic or non-neoplastic disorder that affects one of the cranial nerves." ;
rdfs:subClassOf obo:MONDO_0005071 .
obo:HP_0011014 a rdfs:Class ;
rdfs:label "Abnormal glucose homeostasis" ;
rdfs:comment "Abnormality of glucose homeostasis." ;
rdfs:subClassOf obo:HP_0012337 .
obo:ECTO_0000516 a rdfs:Class ;
rdfs:label "exposure to hormone" ;
rdfs:comment "An exposure to hormone." ;
rdfs:subClassOf obo:ECTO_0000543 , obo:ECTO_0000672 .
obo:MONDO_0005552 a rdfs:Class ;
rdfs:label "ocular vascular disorder" ;
rdfs:comment "A disorder that is caused by pathologic changes in the ocular vasculature." ;
rdfs:subClassOf obo:MONDO_0005328 , obo:MONDO_0005385 .
obo:MONDO_0000646 a rdfs:Class ;
rdfs:label "ovarian benign neoplasm" ;
rdfs:comment "A non-metastasizing neoplasm that arises from the ovary. Representative examples include serous cystadenoma, mucinous cystadenoma, clear cell adenofibroma, benign Brenner tumor, thecoma, and fibroma." ;
rdfs:subClassOf obo:MONDO_0000624 , obo:MONDO_0021068 .
obo:MONDO_0024276 a rdfs:Class ;
rdfs:label "glandular cell neoplasm" ;
rdfs:subClassOf obo:MONDO_0005626 .
obo:MONDO_0001416 a rdfs:Class ;
rdfs:label "female reproductive organ cancer" ;
rdfs:comment "A primary or metastatic malignant neoplasm involving the female reproductive system. Representative examples include endometrial carcinoma, cervical carcinoma, ovarian carcinoma, uterine corpus leiomyosarcoma, adenosarcoma, malignant mixed mesodermal (mullerian) tumor, and gestational choriocarcinoma." ;
rdfs:subClassOf obo:MONDO_0002149 , obo:MONDO_0021148 .
obo:MONDO_0005462 a rdfs:Class ;
rdfs:label "primitive neuroectodermal tumor" ;
rdfs:comment "A malignant neoplasm that originates in the neuroectoderm. The neuroectoderm constitutes the portion of the ectoderm of the early embryo that gives rise to the central and peripheral nervous systems and includes some glial cell precursors." ;
rdfs:subClassOf obo:MONDO_0005564 , obo:MONDO_0021193 .
obo:MONDO_0006292 a rdfs:Class ;
rdfs:label "malignant mesothelioma" ;
rdfs:comment "A malignant neoplasm of the pleura or peritoneum, arising from mesothelial cells. It is associated with exposure to asbestos." ;
rdfs:subClassOf obo:MONDO_0004992 , obo:MONDO_0005065 .
obo:HP_5210001 a rdfs:Class ;
rdfs:label "Unusual gram-positive bacterial infection" ;
rdfs:comment "Increased susceptibility to gram-positive bacterial infections as manifested by recurrent or severe/invasive infection with gram-positive organisms." ;
rdfs:subClassOf obo:HP_5210000 .
obo:MONDO_0002531 a rdfs:Class ;
rdfs:label "skin neoplasm" ;
rdfs:comment "A benign or malignant tumor involving the skin. Representative examples of benign skin neoplasms include the benign melanocytic skin nevus, acanthoma, sebaceous adenoma, sweat gland adenoma, lipoma, hemangioma, fibroma, and benign fibrous histiocytoma. Representative examples of malignant skin neoplasms include basal cell carcinoma, squamous cell carcinoma, melanoma, and Kaposi sarcoma." ;
rdfs:subClassOf obo:MONDO_0005070 , obo:MONDO_0005093 .
obo:IAO_8000011 a rdfs:Class ;
rdfs:label "external import ontology module"@en ;
rdfs:comment "An imported ontology module that is derived from an external ontology. Derivation methods include the OWLAPI SLME approach."@en ;
rdfs:subClassOf obo:IAO_8000005 .
obo:MONDO_0005649 a rdfs:Class ;
rdfs:label "appendicitis" ;
rdfs:comment "Acute inflammation of the vermiform appendix." ;
rdfs:subClassOf obo:MONDO_0002031 , obo:MONDO_0002269 , obo:MONDO_0056798 .
obo:MONDO_0005451 a rdfs:Class ;
rdfs:label "eating disorder" ;
rdfs:comment "A broad group of psychological disorders with abnormal eating behaviors leading to physiological effects from overeating or insufficient food intake." ;
rdfs:subClassOf obo:MONDO_0002025 , obo:MONDO_0005137 .
obo:MONDO_0019340 a rdfs:Class ;
rdfs:label "scleroderma" ;
rdfs:comment "Scleroderma is a rare autoimmune connective tissue disorder characterized by abnormal hardening of the skin and, sometimes, other organs. It is classified into two main forms: localized scleroderma and systemic sclerosis (SSc), the latter comprising three subsets; diffuse cutaneous SSc (dcSSc), limited cutaneous SSc (lcSSc) and limited SSc (lSSc)." ;
rdfs:subClassOf obo:MONDO_0005554 , obo:MONDO_0007179 .
obo:MONDO_0000624 a rdfs:Class ;
rdfs:label "benign female reproductive system neoplasm" ;
rdfs:comment "A non-metastasizing neoplasm that arises from the female reproductive system. Representative examples include uterine corpus leiomyoma, endocervical polyp, and benign ovarian germ cell tumor." ;
rdfs:subClassOf obo:MONDO_0000383 , obo:MONDO_0021148 .
obo:MONDO_0005344 a rdfs:Class ;
rdfs:label "hepatitis B virus infection" ;
rdfs:comment "A viral infection caused by the hepatitis B virus." ;
rdfs:subClassOf obo:MONDO_0005786 , obo:MONDO_0006011 .
obo:MONDO_0000376 a rdfs:Class ;
rdfs:label "respiratory system cancer" ;
rdfs:comment "A malignant neoplasm involving the respiratory system" ;
rdfs:subClassOf obo:MONDO_0004992 , obo:MONDO_0005087 .
obo:MONDO_0006856 a rdfs:Class ;
rdfs:label "mesothelial neoplasm" ;
rdfs:comment "A benign or malignant neoplasm arising from mesothelial cells. Mesothelial cells are the lining cells of the pleura and peritoneum. -- 2003" ;
rdfs:subClassOf obo:MONDO_0005070 .
obo:ECTO_0900200 a rdfs:Class ;
rdfs:label "exposure to antioxidant via ingestion" ;
rdfs:comment "An exposure to antioxidant via ingestion route." ;
rdfs:subClassOf obo:ECTO_9001647 .
obo:ECTO_0900053 a rdfs:Class ;
rdfs:label "exposure to polyunsaturated fatty acid via ingestion" ;
rdfs:comment "An exposure to polyunsaturated fatty acid via ingestion route." ;
rdfs:subClassOf obo:ECTO_0900406 , obo:ECTO_9002507 .
obo:MONDO_0018905 a rdfs:Class ;
rdfs:label "diffuse large B-cell lymphoma" ;
rdfs:comment "Diffuse large B-cell lymphoma is the most common subtype of non-Hodgkin lymphoma (NHL) in adults characterized by a median age of presentation in the sixth decade of life (but also rarely occurring in adolescents and children) with the initial presentation being single or multiple rapidly growing masses (that may or may not be painful) in nodal or extranodal sites (such as thyroid, skin, breast, gastrointestinal tract, testes, bone, or brain) and that can be accompanied by symptoms of fever, night sweats and weight loss. DLBCL has an aggressive disease course, with the elderly having a poorer prognosis than younger patients, and with relapses being common." ;
rdfs:subClassOf obo:MONDO_0004949 , obo:MONDO_0017595 .
obo:MONDO_0000586 a rdfs:Class ;
rdfs:label "autoimmune disorder of exocrine system" ;
rdfs:comment "A hypersensitivity reaction type II disease that involves the exocrine system." ;
rdfs:subClassOf obo:MONDO_0007179 .
obo:HP_0025502 a rdfs:Class ;
rdfs:label "Overweight" ;
rdfs:comment "Increased body weight with a body mass index of 25-29.9 kg per square meter." ;
rdfs:subClassOf obo:HP_0004324 .
obo:MONDO_0002273 a rdfs:Class ;
rdfs:label "plasma protein metabolism disease" ;
rdfs:comment "An inherited metabolic disorder that involves plasma protein metabolism malfunction." ;
rdfs:subClassOf obo:MONDO_0019052 .
obo:HP_0001677 a rdfs:Class ;
rdfs:label "Coronary artery atherosclerosis" ;
rdfs:comment "Reduction of the diameter of the coronary arteries as the result of an accumulation of atheromatous plaques within the walls of the coronary arteries, which increases the risk of myocardial ischemia." ;
rdfs:subClassOf obo:HP_0002621 , obo:HP_0006704 , obo:HP_0100545 .
obo:MONDO_0001336 a rdfs:Class ;
rdfs:label "familial hyperlipidemia" ;
rdfs:comment "An instance of hyperlipidemia (disease) that is caused by an inherited modification of the individual's genome." ;
rdfs:subClassOf obo:MONDO_0002525 , obo:MONDO_0021187 .
obo:MONDO_0044347 a rdfs:Class ;
rdfs:label "erythrocyte disorder" ;
rdfs:comment "A disease or disorder that involves the erythrocyte." ;
rdfs:subClassOf obo:MONDO_0005570 .
obo:MONDO_0100574 a rdfs:Class ;
rdfs:label "generalized epilepsy" ;
rdfs:comment "Epilepsy that is characterized by generalized seizure types and may have typical interictal and/or ictal EEG findings that accompany generalized seizure types (for example generalized spike-wave)." ;
rdfs:subClassOf obo:MONDO_0005027 .
obo:MONDO_0002427 a rdfs:Class ;
rdfs:label "cerebellar disorder" ;
rdfs:comment "Diseases that affect the structure or function of the cerebellum. Cardinal manifestations of cerebellar dysfunction include dysmetria, gait ataxia, and muscle hypotonia." ;
rdfs:subClassOf obo:MONDO_0005560 .
obo:MONDO_0018660 a rdfs:Class ;
rdfs:label "hemophilia" ;
rdfs:comment "Hemophilia is a genetic disorder characterized by spontaneous hemorrhage or prolonged bleeding due to factor VIII or IX deficiency." ;
rdfs:subClassOf obo:MONDO_0002242 .
obo:MONDO_0002081 a rdfs:Class ;
rdfs:label "musculoskeletal system disorder" ;
rdfs:comment "A disease involving the musculoskeletal system." ;
rdfs:subClassOf obo:MONDO_7770006 .
obo:ECTO_9002153 a rdfs:Class ;
rdfs:label "exposure to isocyanates" ;
rdfs:comment "An exposure to isocyanates." ;
rdfs:subClassOf obo:ECTO_0000371 , obo:ECTO_9000190 .
obo:MONDO_0004784 a rdfs:Class ;
rdfs:label "allergic asthma" ;
rdfs:comment "A asthma with a basis in a pathological type I hypersensitivity reaction." ;
rdfs:subClassOf obo:MONDO_0000771 , obo:MONDO_0004979 .
obo:MONDO_0100118 a rdfs:Class ;
rdfs:label "hereditary skin disorder" ;
rdfs:comment "An instance of skin disease that is caused by a modification of the individual's genome." ;
rdfs:subClassOf obo:MONDO_0003847 , obo:MONDO_0005093 .
obo:MONDO_0003659 a rdfs:Class ;
rdfs:label "pediatric lymphoma" ;
rdfs:comment "A Hodgkin or non-Hodgkin lymphoma that occurs during childhood." ;
rdfs:subClassOf obo:MONDO_0005062 , obo:MONDO_0006517 .
obo:MONDO_0005008 a rdfs:Class ;
rdfs:label "colorectal adenocarcinoma" ;
rdfs:comment "The most common type of colorectal carcinoma. It is characterized by the presence of malignant glandular epithelial cells invading through the muscularis mucosa into the submucosa. Histologic variants include mucinous adenocarcinoma, signet ring cell carcinoma, medullary carcinoma, serrated adenocarcinoma, cribriform comedo-type adenocarcinoma, and micropapillary adenocarcinoma." ;
rdfs:subClassOf obo:MONDO_0004970 , obo:MONDO_0024331 .
obo:MONDO_0006704 a rdfs:Class ;
rdfs:label "CNS demyelinating autoimmune disease" ;
rdfs:comment "Conditions characterized by loss or dysfunction of myelin (see myelin sheath) in the brain, spinal cord, or optic nerves secondary to autoimmune mediated processes. This may take the form of a humoral or cellular immune response directed toward myelin or oligodendroglia associated autoantigens." ;
rdfs:subClassOf obo:MONDO_0007179 .
obo:BFO_0000004 a rdfs:Class ;
rdfs:label "independent continuant"@en ;
rdfs:comment "b is an independent continuant = Def. b is a continuant which is such that there is no c and no t such that b s-depends_on c at t. (axiom label in BFO2 Reference: [017-002])"@en ;
rdfs:subClassOf obo:BFO_0000002 .
obo:ECTO_9000190 a rdfs:Class ;
rdfs:label "exposure to organonitrogen compound" ;
rdfs:comment "An exposure to organonitrogen compound." ;
rdfs:subClassOf obo:ECTO_0000135 , obo:ECTO_9000404 .
obo:ECTO_7000138 a rdfs:Class ;
rdfs:label "exposure to diesel exhaust" ;
rdfs:comment "A exposure event involving the interaction of an exposure receptor to diesel exhaust." ;
rdfs:subClassOf obo:ECTO_7000058 .
obo:ECTO_9000404 a rdfs:Class ;
rdfs:label "exposure to nitrogen" ;
rdfs:comment "An exposure to nitrogen molecular entity." ;
rdfs:subClassOf obo:ECTO_0000231 .
obo:BFO_0000015 a rdfs:Class ;
rdfs:label "process"@en ;
rdfs:comment "p is a process = Def. p is an occurrent that has temporal proper parts and for some time t, p s-depends_on some material entity at t. (axiom label in BFO2 Reference: [083-003])"@en ;
rdfs:subClassOf obo:BFO_0000003 .
obo:MONDO_0017344 a rdfs:Class ;
rdfs:label "Epstein-Barr virus-associated carcinoma" ;
rdfs:subClassOf obo:MONDO_0017342 .
obo:MONDO_0013730 a rdfs:Class ;
rdfs:label "graft versus host disease" ;
rdfs:comment "An immune system disorder that occurs after allogeneic hematopoietic stem cell transplant and is a reaction of donor immune cells against host tissues. Activated donor T cells damage host epithelial cells after an inflammatory cascade that begins with the preparative regimen." ;
rdfs:subClassOf obo:MONDO_0005046 , obo:MONDO_0700222 .
obo:MONDO_0001660 a rdfs:Class ;
rdfs:label "proliferative diabetic retinopathy" ;
rdfs:comment "Advanced retinopathy due to diabetes mellitus characterized by the formation of new vessels in the retina. The new vessels are abnormal and fragile. If hemorrhage occurs due to the vascular fragility, there is increased risk of vision loss or blindness." ;
rdfs:subClassOf obo:MONDO_0005266 .
obo:MONDO_0005394 a rdfs:Class ;
rdfs:label "brain infarction" ;
rdfs:comment "Tissue necrosis in any area of the brain, including the cerebral hemispheres, the cerebellum, and the brain stem. Brain infarction is the result of a cascade of events initiated by inadequate blood flow through the brain that is followed by hypoxia and hypoglycemia in brain tissue. Damage may be temporary, permanent, selective or pan-necrosis." ;
rdfs:subClassOf obo:MONDO_0011057 .
obo:MONDO_0001020 a rdfs:Class ;
rdfs:label "amblyopia" ;
rdfs:comment "Decreased vision that results from abnormal visual development." ;
rdfs:subClassOf obo:MONDO_0021084 .
obo:MONDO_0003781 a rdfs:Class ;
rdfs:label "bronchitis" ;
rdfs:comment "An acute or chronic inflammatory process affecting the bronchi." ;
rdfs:subClassOf obo:MONDO_0001358 , obo:MONDO_0021925 .
obo:MONDO_0005299 a rdfs:Class ;
rdfs:label "brain ischemia" ;
rdfs:comment "Diminished or absent blood supply to the brain caused by obstruction (thrombosis or embolism) of an artery resulting in neurologic damage." ;
rdfs:subClassOf obo:MONDO_0005053 , obo:MONDO_0011057 .
obo:MONDO_0006816 a rdfs:Class ;
rdfs:label "arthropathy" ;
rdfs:comment "Any disorder of the joints." ;
rdfs:subClassOf obo:MONDO_0005172 .
obo:ECTO_6000008 a rdfs:Class ;
rdfs:label "exposure to drug abuse" ;
rdfs:comment "An exposure event involving Drug Abuse" ;
rdfs:subClassOf obo:ECTO_6000007 .
obo:MONDO_0016105 a rdfs:Class ;
rdfs:label "acquired skeletal muscle disease" ;
rdfs:comment "An instance of skeletal muscle disease that is acquired during the lifetime of the individual." ;
rdfs:subClassOf obo:MONDO_0020120 .
obo:MONDO_0002334 a rdfs:Class ;
rdfs:label "hematopoietic and lymphoid system neoplasm" ;
rdfs:comment "Neoplasms of the hematopoietic system, including hematopoietic cell neoplasms (e.g. leukemias, lymphomas) and non-hematopoietic cell neoplasms that can affect the hematopoietic system (e.g. lymph node and splenic sarcomas). --2003" ;
rdfs:subClassOf obo:MONDO_0005070 , obo:MONDO_0005570 .
obo:MONDO_0005381 a rdfs:Class ;
rdfs:label "bone disorder" ;
rdfs:comment "Diseases of bones." ;
rdfs:subClassOf obo:MONDO_0005172 .
obo:MONDO_0002331 a rdfs:Class ;
rdfs:label "nephrosis" ;
rdfs:comment "Pathological processes of the KIDNEY without inflammatory or neoplastic components. Nephrosis may be a primary disorder or secondary complication of other diseases. It is characterized by the NEPHROTIC SYNDROME indicating the presence of PROTEINURIA and HYPOALBUMINEMIA with accompanying EDEMA." ;
rdfs:subClassOf obo:MONDO_0005240 .
obo:MONDO_0002562 a rdfs:Class ;
rdfs:label "demyelinating disease" ;
rdfs:comment "A broad group of disorders that affect the myelin sheaths that cover the neurons. Myelin sheathes cover neuronal axons in the central and peripheral nervous system and function to increase traveling impulse speeds. Disruption of this sheath impairs neuronal transmission and can result in disorders such as multiple sclerosis and Guillain-Barre syndrome, among others." ;
rdfs:subClassOf obo:MONDO_0005559 , obo:MONDO_0021147 .
obo:MONDO_0005070 a rdfs:Class ;
rdfs:label "neoplasm" ;
rdfs:comment "A benign or malignant tissue growth resulting from uncontrolled cell proliferation. Benign neoplastic cells resemble normal cells without exhibiting significant cytologic atypia, while malignant cells exhibit overt signs such as dysplastic features, atypical mitotic figures, necrosis, nuclear pleomorphism, and anaplasia. Representative examples of benign neoplasms include papillomas, cystadenomas, and lipomas; malignant neoplasms include carcinomas, sarcomas, lymphomas, and leukemias." ;
rdfs:subClassOf obo:MONDO_0023370 .
obo:MONDO_0005086 a rdfs:Class ;
rdfs:label "renal cell carcinoma" ;
rdfs:comment "A carcinoma that arises from glandular epithelial cells of the kidney" ;
rdfs:subClassOf obo:MONDO_0004970 , obo:MONDO_0005206 .
obo:MONDO_0004849 a rdfs:Class ;
rdfs:label "pulmonary emphysema" ;
rdfs:comment "A subcategory of chronic obstructive pulmonary disease (COPD). It occurs in people who smoke and suffer from chronic bronchitis. It is characterized by inflation of the alveoli, alveolar wall damage, and reduction in the number of alveoli, resulting in difficulty breathing." ;
rdfs:subClassOf obo:MONDO_0005002 .
obo:MONDO_0006054 a rdfs:Class ;
rdfs:label "reproductive system neoplasm" ;
rdfs:comment "A benign or malignant, primary or metastatic neoplasm affecting the male and female reproductive system." ;
rdfs:subClassOf obo:MONDO_0005039 , obo:MONDO_0005070 .
obo:MONDO_0000942 a rdfs:Class ;
rdfs:label "corneal disorder" ;
rdfs:comment "A non-neoplastic or neoplastic disorder that affects the cornea. Representative examples include keratitis, bullous keratopathy, and squamous cell carcinoma." ;
rdfs:subClassOf obo:MONDO_0005328 .
obo:MONDO_0001358 a rdfs:Class ;
rdfs:label "bronchial disorder" ;
rdfs:comment "A disease involving the bronchus." ;
rdfs:subClassOf obo:MONDO_0000270 .
obo:HP_0100543 a rdfs:Class ;
rdfs:label "Cognitive impairment" ;
rdfs:comment "Abnormal cognition is characterized by deficits in thinking, reasoning, or remembering." ;
rdfs:subClassOf obo:HP_0011446 .
obo:MONDO_0011565 a rdfs:Class ;
rdfs:label "metabolic syndrome X" ;
rdfs:subClassOf obo:MONDO_0000816 .
obo:MONDO_0019086 a rdfs:Class ;
rdfs:label "carcinoma of esophagus" ;
rdfs:comment "Esophageal carcinoma (EC) is a tumor arising in the epithelial cells lining the esophagus and can be divided into two subtypes: esophageal squamous cell carcinoma (ESCC) and esophageal adenocarcinoma (EAC)." ;
rdfs:subClassOf obo:MONDO_0006181 , obo:MONDO_0007576 .
obo:MONDO_0024635 a rdfs:Class ;
rdfs:label "small intestine disorder" ;
rdfs:comment "A disease that involves the small intestine." ;
rdfs:subClassOf obo:MONDO_0005020 .
obo:MONDO_0005002 a rdfs:Class ;
rdfs:label "chronic obstructive pulmonary disease" ;
rdfs:comment "A chronic and progressive lung disorder characterized by the loss of elasticity of the bronchial tree and the air sacs, destruction of the air sacs wall, thickening of the bronchial wall, and mucous accumulation in the bronchial tree. The pathologic changes result in the disruption of the air flow in the bronchial airways. Signs and symptoms include shortness of breath, wheezing, productive cough, and chest tightness. The two main types of chronic obstructive pulmonary disease are chronic obstructive bronchitis and emphysema." ;
rdfs:subClassOf obo:MONDO_0002267 , obo:MONDO_0002567 .
obo:HP_0001871 a rdfs:Class ;
rdfs:label "Abnormality of blood and blood-forming tissues" ;
rdfs:comment "An abnormality of the hematopoietic system." ;
rdfs:subClassOf obo:HP_0000118 .
obo:MONDO_0020800 a rdfs:Class ;
rdfs:label "demyelinating disease of central nervous system" ;
rdfs:comment "Any condition in which there is degeneration of the myelin sheath that covers the nerves of the central nervous system." ;
rdfs:subClassOf obo:MONDO_0002562 .
obo:ECTO_9001347 a rdfs:Class ;
rdfs:label "exposure to sodium chloride" ;
rdfs:comment "An exposure to sodium chloride." ;
rdfs:subClassOf obo:ECTO_0000135 , obo:ECTO_9000021 , obo:ECTO_9000077 , obo:ECTO_9000172 .
obo:MONDO_0000358 a rdfs:Class ;
rdfs:label "orofacial cleft" ;
rdfs:comment "A disorder of facial skeleton that is characterized by cleft lip and/or cleft palate that result in feeding, speech and hearing problems caused by failures during development." ;
rdfs:subClassOf obo:MONDO_0003847 , obo:MONDO_0023369 .
obo:MONDO_0006559 a rdfs:Class ;
rdfs:label "hidradenitis suppurativa" ;
rdfs:comment "A chronic suppurative and cicatricial disease of the apocrine glands occurring chiefly in the axillae in women and in the groin and anal regions in men. It is characterized by poral occlusion with secondary bacterial infection, evolving into abscesses which eventually rupture. As the disease becomes chronic, ulcers appear, sinus tracts enlarge, fistulas develop, and fibrosis and scarring become evident." ;
rdfs:subClassOf obo:MONDO_0002260 .
obo:MONDO_0002236 a rdfs:Class ;
rdfs:label "ocular cancer" ;
rdfs:comment "A benign or malignant neoplasm affecting the structures of the eye." ;
rdfs:subClassOf obo:MONDO_0000649 , obo:MONDO_0005627 , obo:MONDO_0021220 .
obo:MONDO_0024458 a rdfs:Class ;
rdfs:label "disorder of visual system" ;
rdfs:comment "A disease that involves the visual system." ;
rdfs:subClassOf obo:MONDO_7770006 .
obo:MONDO_0007488 a rdfs:Class ;
rdfs:label "Lewy body dementia" ;
rdfs:comment "A progressive form of dementia characterized by the presence of protein deposits called Lewy bodies in the midbrain and cerebral cortex, and loss of cholinergic and dopaminergic neurons. The signs and symptoms overlap with Alzheimer and Parkinson disease." ;
rdfs:subClassOf obo:MONDO_0000510 , obo:MONDO_0001627 .
obo:ECTO_6000021 a rdfs:Class ;
rdfs:label "exposure to eating behavior" ;
rdfs:comment "An exposure event involving Dietary Practices" ;
rdfs:subClassOf obo:ECTO_6000016 .
obo:MONDO_0035375 a rdfs:Class ;
rdfs:label "multisystem inflammatory syndrome in children and adults" ;
rdfs:subClassOf obo:MONDO_0100320 .
obo:ECTO_8000000 a rdfs:Class ;
rdfs:label "exposure to environmental process" ;
rdfs:comment "A exposure event involving the interaction of an exposure receptor to environmental system process." ;
rdfs:subClassOf obo:ExO_0000002 .
obo:MONDO_0005836 a rdfs:Class ;
rdfs:label "male reproductive organ cancer" ;
rdfs:comment "A primary or metastatic malignant neoplasm involving the male reproductive system. Representative examples include prostate carcinoma, penile carcinoma, testicular seminoma, and testicular embryonal carcinoma." ;
rdfs:subClassOf obo:MONDO_0002149 , obo:MONDO_0024582 .
obo:MONDO_0005136 a rdfs:Class ;
rdfs:label "malaria" ;
rdfs:comment "Malaria is a serious and sometimes fatal disease caused by a parasite that commonly infects a certain type of mosquito which feeds on humans. Infection with malaria parasites may result in a wide variety of symptoms, ranging from absent or very mild symptoms to severe disease and even death. People who get malaria are typically very sick with high fevers, shaking chills, and flu-like illness. In general, malaria is a curable disease if diagnosed and treated promptly and correctly.Treatment depends on many factors including disease severity, the species of malaria parasite causing the infection and the part of the world in which the infection was acquired." ;
rdfs:subClassOf obo:MONDO_0002428 , obo:MONDO_0044347 , obo:MONDO_0100120 .
obo:MONDO_0000568 a rdfs:Class ;
rdfs:label "autoimmune disorder of central nervous system" ;
rdfs:comment "A hypersensitivity reaction type II disease that involves the central nervous system." ;
rdfs:subClassOf obo:MONDO_0002602 , obo:MONDO_0002977 .
obo:HP_0011805 a rdfs:Class ;
rdfs:label "Abnormal skeletal muscle morphology" ;
rdfs:comment "A structural abnormality of a skeletal muscle." ;
rdfs:subClassOf obo:HP_0003011 .
obo:MONDO_0006952 a rdfs:Class ;
rdfs:label "retinopathy of prematurity" ;
rdfs:comment "A bilateral retinopathy characterized by neovascularization, scarring, retinal detachment, and eventually blindness. It may be mild or severe. It occurs in babies born prematurely. Causes include oxygen toxicity and hypoxia." ;
rdfs:subClassOf obo:MONDO_1040041 .
obo:HP_0033354 a rdfs:Class ;
rdfs:label "Abnormal urine metabolite level" ;
rdfs:comment "Any deviation from the normal amount of a metabolite in urine." ;
rdfs:subClassOf obo:HP_0003110 .
obo:HP_0000152 a rdfs:Class ;
rdfs:label "Abnormality of head or neck" ;
rdfs:comment "An abnormality of head and neck." ;
rdfs:subClassOf obo:HP_0000118 .
obo:MONDO_0005154 a rdfs:Class ;
rdfs:label "liver disorder" ;
rdfs:comment "A disease involving the liver." ;
rdfs:subClassOf obo:MONDO_0002515 , obo:MONDO_0005151 .
obo:MONDO_0021058 a rdfs:Class ;
rdfs:label "neoplastic syndrome" ;
rdfs:comment "A broad classification for disorders in which the development of neoplasms typically occur in association with a characteristic set of signs or symptoms. These disorders may be inherited or acquired." ;
rdfs:subClassOf obo:MONDO_0002254 , obo:MONDO_0023370 .
obo:MONDO_0100120 a rdfs:Class ;
rdfs:label "vector-borne disease" ;
rdfs:comment "An infectious disease where a pathogen is carried and transmitted by another organism that acts as disease vector." ;
rdfs:subClassOf obo:MONDO_0005550 .
obo:MONDO_0005147 a rdfs:Class ;
rdfs:label "type 1 diabetes mellitus" ;
rdfs:comment "A chronic condition characterized by minimal or absent production of insulin by the pancreas." ;
rdfs:subClassOf obo:MONDO_0000569 , obo:MONDO_0000588 , obo:MONDO_0005015 .
obo:MONDO_0006256 a rdfs:Class ;
rdfs:label "invasive breast carcinoma" ;
rdfs:comment "A carcinoma that infiltrates the breast parenchyma. The vast majority are adenocarcinomas arising from the terminal ductal lobular unit (TDLU). Often, the invasive adenocarcinoma co-exists with ductal or lobular carcinoma in situ. It is the most common carcinoma affecting women." ;
rdfs:subClassOf obo:MONDO_0004989 , obo:MONDO_0040677 .
obo:MONDO_0015459 a rdfs:Class ;
rdfs:label "nasopharyngeal carcinoma" ;
rdfs:comment "A carcinoma arising from the nasopharyngeal epithelium. It includes the following types: keratinizing squamous cell carcinoma, nonkeratinizing carcinoma (differentiated and undifferentiated), basaloid squamous cell carcinoma, and papillary adenocarcinoma." ;
rdfs:subClassOf obo:MONDO_0002038 , obo:MONDO_0017344 , obo:MONDO_0021315 , obo:MONDO_0021345 .
obo:HP_0034267 a rdfs:Class ;
rdfs:label "Pelvic pain" ;
rdfs:comment "Pain perceived in the area of the pelvis, the lower part of the abdomen located between the hip bones." ;
rdfs:subClassOf obo:HP_0012531 .
obo:ECTO_9001537 a rdfs:Class ;
rdfs:label "exposure to polychlorinated dibenzodioxines and related compounds" ;
rdfs:comment "An exposure to polychlorinated dibenzodioxines and related compounds." ;
rdfs:subClassOf obo:ECTO_0000135 .
obo:HP_0031567 a rdfs:Class ;
rdfs:label "Abnormal aortic valve cusp morphology" ;
rdfs:comment "Any structural anomaly of the aortic valve leaflets." ;
rdfs:subClassOf obo:HP_0001646 .
obo:ECTO_8000038 a rdfs:Class ;
rdfs:label "exposure to water pollution" ;
rdfs:comment "A exposure event involving the interaction of an exposure receptor to water pollution." ;
rdfs:subClassOf obo:ECTO_8000019 .
obo:HP_0011003 a rdfs:Class ;
rdfs:label "High myopia" ;
rdfs:comment "A severe form of myopia with greater than -6.00 diopters." ;
rdfs:subClassOf obo:HP_0000545 .
obo:MONDO_0005244 a rdfs:Class ;
rdfs:label "peripheral neuropathy" ;
rdfs:comment "A disorder affecting the peripheral nervous system. It manifests with pain, tingling, numbness, and muscle weakness. It may be the result of physical injury, toxic substances, viral diseases, diabetes, renal failure, cancer, and drugs." ;
rdfs:subClassOf obo:MONDO_0003620 , obo:MONDO_0019056 .
obo:MONDO_0020579 a rdfs:Class ;
rdfs:label "mucositis" ;
rdfs:comment "Inflammation of the mucous membranes." ;
rdfs:subClassOf obo:MONDO_0021166 .
obo:MONDO_0021230 a rdfs:Class ;
rdfs:label "uterine cervix neoplasm" ;
rdfs:comment "A neoplasm (disease) that involves the uterine cervix." ;
rdfs:subClassOf obo:MONDO_0002256 , obo:MONDO_0021353 .
obo:MONDO_0002409 a rdfs:Class ;
rdfs:label "auditory system disorder" ;
rdfs:comment "A disease involving the auditory system." ;
rdfs:subClassOf obo:MONDO_7770006 .
obo:ECTO_0001591 a rdfs:Class ;
rdfs:label "exposure to occupation" ;
rdfs:comment "An exposure event involving Occupation" ;
rdfs:subClassOf obo:ExO_0000002 .
obo:ECTO_9000077 a rdfs:Class ;
rdfs:label "exposure to chlorine" ;
rdfs:comment "An exposure to chlorine molecular entity." ;
rdfs:subClassOf obo:ECTO_0000231 .
obo:MONDO_0044986 a rdfs:Class ;
rdfs:label "lymphoid system disorder" ;
rdfs:comment "A disease or disorder that involves the lymphoid system." ;
rdfs:subClassOf obo:MONDO_0005046 .
obo:MONDO_0005031 a rdfs:Class ;
rdfs:label "fibromatosis" ;
rdfs:comment "A poorly circumscribed neoplasm arising from the soft tissues. It is characterized by the presence of spindle-shaped fibroblasts and an infiltrative growth pattern." ;
rdfs:subClassOf obo:MONDO_0006209 .
obo:MONDO_0002269 a rdfs:Class ;
rdfs:label "gastroenteritis" ;
rdfs:comment "An inflammatory disorder that affects the upper and lower gastrointestinal tract. Most commonly, this is attributed to viruses; however bacteria, parasites or adverse reactions can also be the culprit. Symptoms include acute diarrhea and vomiting." ;
rdfs:subClassOf obo:MONDO_0005020 , obo:MONDO_0021166 .
obo:MONDO_0005350 a rdfs:Class ;
rdfs:label "abdominal aortic aneurysm" ;
rdfs:comment "Enlargement and ballooning of the vessel that supplies arterial blood to the abdomen, pelvis and legs." ;
rdfs:subClassOf obo:MONDO_0005160 .
obo:ECTO_9001227 a rdfs:Class ;
rdfs:label "exposure to phosphorus" ;
rdfs:comment "An exposure to phosphorus molecular entity." ;
rdfs:subClassOf obo:ECTO_0000231 .
obo:MONDO_0005917 a rdfs:Class ;
rdfs:label "placenta disorder" ;
rdfs:comment "A disease involving the placenta." ;
rdfs:subClassOf obo:MONDO_0002654 , obo:MONDO_0024575 .
obo:HP_0012252 a rdfs:Class ;
rdfs:label "Abnormal respiratory system morphology" ;
rdfs:comment "A structural anomaly of the respiratory system." ;
rdfs:subClassOf obo:HP_0002086 .
obo:ECTO_8000011 a rdfs:Class ;
rdfs:label "exposure to earthquake" ;
rdfs:comment "A exposure event involving the interaction of an exposure receptor to earthquake." ;
rdfs:subClassOf obo:ECTO_8000000 .
obo:MONDO_0005020 a rdfs:Class ;
rdfs:label "intestinal disorder" ;
rdfs:comment "A non-neoplastic or neoplastic disorder that affects the small or large intestine." ;
rdfs:subClassOf obo:MONDO_0004335 .
obo:MONDO_0002009 a rdfs:Class ;
rdfs:label "major depressive disorder" ;
rdfs:comment "An episode of depression lasting two or more weeks without an intervening episode of mania." ;
rdfs:subClassOf obo:MONDO_0002050 .
obo:MONDO_0007743 a rdfs:Class ;
rdfs:label "attention deficit-hyperactivity disorder" ;
rdfs:comment "A disorder characterized by a marked pattern of inattention and/or hyperactivity-impulsivity that is inconsistent with developmental level and clearly interferes with functioning in at least two settings (e.g. at home and at school). When present, the symptoms of hyperactivity are most often present before the age of 7 years. There are three recognized presentations or subtypes from most to least common: combined type, inattentive/distractible type, hyperactive/impulsive type." ;
rdfs:subClassOf obo:MONDO_0000592 .
obo:HP_0020169 a rdfs:Class ;
rdfs:label "Abnormal drug response" ;
rdfs:comment "An anomalous response to a medication related to individual variation in metabolic or immune response to drugs varying from potentially from potentially life-threatening adverse drug reactions to alteration of therapeutic efficacy." ;
rdfs:subClassOf obo:HP_0001939 .
obo:MONDO_0003014 a rdfs:Class ;
rdfs:label "rhinitis" ;
rdfs:comment "An inflammation of the mucous membrane lining the nose, usually associated with nasal discharge." ;
rdfs:subClassOf obo:MONDO_0002232 , obo:MONDO_0020579 .
obo:MONDO_0010150 a rdfs:Class ;
rdfs:label "head and neck squamous cell carcinoma" ;
rdfs:comment "A squamous cell carcinoma that arises from any of the following anatomic sites: lip and oral cavity, nasal cavity, paranasal sinuses, pharynx, larynx, and salivary glands." ;
rdfs:subClassOf obo:MONDO_0002038 , obo:MONDO_0005096 .
obo:ECTO_3000174 a rdfs:Class ;
rdfs:label "exposure to Schistosoma mansoni" ;
rdfs:comment "A history of exposure to Schistosoma mansoni." ;
rdfs:subClassOf obo:ECTO_3000000 .
obo:ECTO_9000021 a rdfs:Class ;
rdfs:label "exposure to alkali metal salt" ;
rdfs:comment "An exposure to alkali metal salt." ;
rdfs:subClassOf obo:ECTO_9000409 .
obo:MONDO_0004950 a rdfs:Class ;
rdfs:label "gastric carcinoma" ;
rdfs:comment "A carcinoma that arises from epithelial cells of the stomach." ;
rdfs:subClassOf obo:MONDO_0001056 , obo:MONDO_0006181 .
obo:MONDO_0004647 a rdfs:Class ;
rdfs:label "in situ carcinoma" ;
rdfs:comment "A malignant epithelial neoplasm which is confined to the epithelial layer without evidence of further tissue invasion." ;
rdfs:subClassOf obo:MONDO_0004993 , obo:MONDO_0020665 , obo:MONDO_0021074 .
obo:MONDO_0024477 a rdfs:Class ;
rdfs:label "liver and intrahepatic bile duct neoplasm" ;
rdfs:comment "A benign or malignant neoplasm that affects the liver parenchyma or intrahepatic bile ducts. Representative examples of benign neoplasms include hepatocellular adenoma, and bile duct adenoma. Representative examples of malignant neoplasms include hepatocellular carcinoma, intrahepatic cholangiocarcinoma, and lymphoma." ;
rdfs:subClassOf obo:MONDO_0002082 , obo:MONDO_0002514 , obo:MONDO_0005154 .
obo:ECTO_0000135 a rdfs:Class ;
rdfs:label "exposure to organic compound" ;
rdfs:comment "An exposure to organic molecular entity." ;
rdfs:subClassOf obo:ECTO_0000231 .
obo:HP_0009121 a rdfs:Class ;
rdfs:label "Abnormal axial skeleton morphology" ;
rdfs:comment "An abnormality of the axial skeleton, which comprises the skull, the vertebral column, the ribs and the sternum." ;
rdfs:subClassOf obo:HP_0011842 .
obo:HP_0025766 a rdfs:Class ;
rdfs:label "Abnormal affect" ;
rdfs:comment "An anomaly in intensity, frequency, or duration of the verbal or behavioral expression of emotions, feelings, or thoughts." ;
rdfs:subClassOf obo:HP_0011446 .
obo:MONDO_0005379 a rdfs:Class ;
rdfs:label "neurotic disorder" ;
rdfs:comment "A form of functional mental illness that manifests in distressed emotional reactions such as anxiety, obsessive thoughts, compulsive behaviors, or irrational fears." ;
rdfs:subClassOf obo:MONDO_0005618 .
a rdfs:Class ;
rdfs:label "cohort aggregation"@en ;
rdfs:comment "A study, project or consortium that compares multiple cohorts." .
a rdf:Property ;
rdfs:label "has_disease_of_interest"@en ;
rdfs:comment "A relation between a cohort and a disease it is about: the disease its participants have, the disease they were selected for their risk of, or the disease a population study was set up to study. Asserted only through its sub-properties, which say which of these it is, as a type of the cohort (has_patients_with some D) carrying the sentence that shows the recruitment basis or purpose, its source and the disease as the source names it. A general population cohort, a biobank of unselected donors or a cohort with a broad purpose has no disease of interest."@en ;
rdfs:range .
a rdf:Property ;
rdfs:label "hasCohort"@en ;
rdfs:comment "A relation between a cohort aggregation and a cohort, or another cohort aggregation, whose participants or data it combines or compares."@en ;
rdfs:domain ;
rdfs:range xsd:string .
a rdf:Property ;
rdfs:label "has_exposure_of_interest"@en ;
rdfs:comment "A relation between a cohort and an environmental exposure it is about: the exposure its participants were selected for, or the exposure the cohort was designed to study. Asserted only through its sub-properties, which say which of these it is, as a type of the cohort (has_participants_with_exposure some E) carrying the sentence that shows the recruitment basis or purpose, its source and the exposure as the source names it. A general population, biobank, disease or trial cohort that measures exposures among many other variables has no exposure of interest, and a genotype, a medication, a medical procedure or socio-economic status by itself is not an exposure here."@en ;
rdfs:range .
a rdf:Property ;
rdfs:label "isCohortOf"@en ;
rdfs:comment "A relation between a cohort, or a cohort aggregation, and a cohort aggregation that combines or compares its participants or data. The inverse of hasCohort."@en ;
rdfs:range .
obo:MONDO_0021669 a rdfs:Class ;
rdfs:label "post-infectious disorder" ;
rdfs:comment "A disorder that follows infection but is distinct from the infection itself and its usual manifestations." ;
rdfs:subClassOf obo:MONDO_7770010 .
obo:MONDO_0001697 a rdfs:Class ;
rdfs:label "reading disorder" ;
rdfs:comment "A learning disability involving difficulty reading resulting primarily from neurological factors which affect any part of the reading process." ;
rdfs:subClassOf obo:MONDO_0004681 .
obo:MONDO_0005081 a rdfs:Class ;
rdfs:label "preeclampsia" ;
rdfs:comment "Preeclampsia is a hypertensive disorder of pregnancy that is characterized by new-onset hypertension with proteinuria presenting after 20 weeks of gestation, and depending on mild or severe forms may initially present with severe headache, visual disturbances, and hyperreflexia." ;
rdfs:subClassOf obo:MONDO_0003847 , obo:MONDO_0045048 .
obo:ECTO_7000063 a rdfs:Class ;
rdfs:label "exposure to water in environment" ;
rdfs:comment "A exposure event involving the interaction of an exposure receptor to liquid water." ;
rdfs:subClassOf obo:ECTO_0000015 .
obo:MONDO_0021166 a rdfs:Class ;
rdfs:label "inflammatory disease" ;
rdfs:comment "A disease involving a pathogenic inflammatory response in the anatomical structure." ;
rdfs:subClassOf obo:MONDO_7770007 .
obo:MONDO_0005159 a rdfs:Class ;
rdfs:label "prostate carcinoma" ;
rdfs:comment "A carcinoma that arises from epithelial cells of the prostate gland." ;
rdfs:subClassOf obo:MONDO_0004993 , obo:MONDO_0008315 .
obo:MONDO_0005101 a rdfs:Class ;
rdfs:label "ulcerative colitis" ;
rdfs:comment "An inflammatory bowel disease involving the mucosal surface of the large intestine and rectum. It may present with an acute or slow onset and follows an intermittent or continuous course. Signs and symptoms include abdominal pain, diarrhea, fever, weight loss, and intestinal hemorrhage." ;
rdfs:subClassOf obo:MONDO_0005292 .
obo:ECTO_0000163 a rdfs:Class ;
rdfs:label "exposure to organic cyclic compound" ;
rdfs:comment "An exposure to organic cyclic compound." ;
rdfs:subClassOf obo:ECTO_0000135 .
obo:MONDO_0000870 a rdfs:Class ;
rdfs:label "childhood acute lymphoblastic leukemia" ;
rdfs:comment "An acute lymphoblastic leukemia occurring during childhood. The majority of cases are B-acute lymphoblastic leukemias. Approximately 15% of the cases are T-acute lymphoblastic leukemias." ;
rdfs:subClassOf obo:MONDO_0003659 , obo:MONDO_0004355 , obo:MONDO_0004967 .
obo:MONDO_0001584 a rdfs:Class ;
rdfs:label "ocular motility disease" ;
rdfs:subClassOf obo:MONDO_0003569 .
obo:MONDO_0044137 a rdfs:Class ;
rdfs:label "vitreous body disorder" ;
rdfs:comment "Any disease affecting the vitreous body of the eye." ;
rdfs:subClassOf obo:MONDO_0005328 .
obo:MONDO_0004993 a rdfs:Class ;
rdfs:label "carcinoma" ;
rdfs:comment "A malignant tumor arising from epithelial cells. Carcinomas that arise from glandular epithelium are called adenocarcinomas, those that arise from squamous epithelium are called squamous cell carcinomas, and those that arise from transitional epithelium are called transitional cell carcinomas. Morphologically, the malignant epithelial cells may display abnormal mitotic figures, anaplasia, and necrosis. Carcinomas are graded by the degree of cellular differentiation as well, moderately, or poorly differentiated. Carcinomas invade the surrounding tissues and tend to metastasize to other anatomic sites. Lung carcinoma, skin carcinoma, breast carcinoma, colon carcinoma, and prostate carcinoma are the most frequently seen carcinomas." ;
rdfs:subClassOf obo:MONDO_0004992 , obo:MONDO_0005626 .
obo:HP_0001679 a rdfs:Class ;
rdfs:label "Abnormal aortic morphology" ;
rdfs:comment "An abnormality of the aorta." ;
rdfs:subClassOf obo:HP_0011004 , obo:HP_0030962 .
obo:HP_0033127 a rdfs:Class ;
rdfs:label "Abnormality of the musculoskeletal system" ;
rdfs:comment "An anomaly of the musculoskeletal system, which consists of the bones of the skeleton, muscles, cartilage, tendons, ligaments, joints, and other connective tissue. The musculoskeletal system supports the weight of the body, maintains body position and produces movements of the body or of parts of the body." ;
rdfs:subClassOf obo:HP_0000118 .
obo:ECTO_0080000 a rdfs:Class ;
rdfs:label "exposure to arsenic in water via ingestion" ;
rdfs:comment "An exposure to arsenic atom mixed in liquid water via ingestion route." ;
rdfs:subClassOf obo:ECTO_0900042 , obo:ECTO_9002355 .
obo:MONDO_0100576 a rdfs:Class ;
rdfs:label "hereditary generalized epilepsy" ;
rdfs:comment "An instance of generalized epilepsy that is caused by an inherited genomic modification in an individual." ;
rdfs:subClassOf obo:MONDO_0100545 , obo:MONDO_0100575 .
obo:ECTO_0001057 a rdfs:Class ;
rdfs:label "exposure to decreased temperature" ;
rdfs:comment "A exposure event involving the interaction of an exposure receptor to decreased temperature." ;
rdfs:subClassOf obo:ECTO_0010001 , obo:ECTO_0010003 .
obo:MONDO_0040677 a rdfs:Class ;
rdfs:label "invasive carcinoma" ;
rdfs:comment "A carcinoma that is not confined to the epithelium, and has spread to the surrounding stroma." ;
rdfs:subClassOf obo:MONDO_0004993 .
obo:MONDO_0005112 a rdfs:Class ;
rdfs:label "malignant pleural mesothelioma" ;
rdfs:comment "A malignant neoplasm that arises from mesothelial cells in the pleura and shows a diffuse growth pattern. It arises on the parietal and sometimes visceral pleura as multiple small nodules that later become confluent and invade the chest wall adipose tissue and muscle. Asbestos exposure is the main cause for the development of pleural malignant mesothelioma. It usually affects patients over sixty years of age. The latency period is long. Patients usually present with pleural effusion, dyspnea and chest wall pain. Additional signs and symptoms include chills, sweating, weight loss, and weakness. Morphologic variants include epithelioid, desmoplastic, sarcomatoid, and biphasic mesothelioma. The clinical course is usually aggressive." ;
rdfs:subClassOf obo:MONDO_0003308 , obo:MONDO_0006292 , obo:MONDO_0006294 .
obo:MONDO_0005160 a rdfs:Class ;
rdfs:label "aortic aneurysm" ;
rdfs:comment "A ruptured aneurysm located in the wall of the proximal portion of the descending aorta proceeding from the arch of the aorta." ;
rdfs:subClassOf obo:MONDO_0005561 .
obo:HP_0030829 a rdfs:Class ;
rdfs:label "Abnormal breath sound" ;
rdfs:comment "An anomalous (adventitious) sound produced by the breathing process." ;
rdfs:subClassOf obo:HP_0002795 .
obo:HP_0006932 a rdfs:Class ;
rdfs:label "Transient psychotic episodes" ;
rdfs:comment "Relatively short-lived periods of psychosis are characterized by the sudden onset of severe disturbances in perception, thinking, and behavior. These episodes typically last for a brief duration, generally ranging from a few days to a few weeks, and are often triggered by a significant stressor or traumatic event." ;
rdfs:subClassOf obo:HP_5200430 .
obo:MONDO_0023369 a rdfs:Class ;
rdfs:label "disorder of facial skeleton" ;
rdfs:comment "A disease that involves the facial skeleton." ;
rdfs:subClassOf obo:MONDO_0024654 .
obo:HP_0012638 a rdfs:Class ;
rdfs:label "Abnormal nervous system physiology" ;
rdfs:comment "A functional anomaly of the nervous system." ;
rdfs:subClassOf obo:HP_0000707 .
obo:BFO_0000002 a rdfs:Class ;
rdfs:label "continuant"@en ;
rdfs:comment "An entity that exists in full at any time in which it exists at all, persists through time while maintaining its identity and has no temporal parts."@en ;
rdfs:subClassOf obo:BFO_0000001 .
obo:HP_0100851 a rdfs:Class ;
rdfs:label "Abnormal emotional state" ;
rdfs:comment "A disturbance in the experience or expression of emotion, characterized by alterations in valence, intensity, frequency, or duration. It may also involve emotional responses that are mismatched, exaggerated, or incongruent relative to internal expectations or external contextual stimuli, such as experiencing negative affect in response to neutral or positive events." ;
rdfs:subClassOf obo:HP_0025766 .
obo:MONDO_0005149 a rdfs:Class ;
rdfs:label "pulmonary hypertension" ;
rdfs:comment "Increased pressure within the pulmonary circulation due to lung or heart disorder." ;
rdfs:subClassOf obo:MONDO_0005044 .
obo:ECTO_7000117 a rdfs:Class ;
rdfs:label "exposure to fine respirable suspended particulate matter" ;
rdfs:comment "A exposure event involving the interaction of an exposure receptor to fine respirable suspended particulate matter." ;
rdfs:subClassOf obo:ECTO_7000116 .
obo:MONDO_0006180 a rdfs:Class ;
rdfs:label "digestive system adenoma" ;
rdfs:comment "A sporadic or less frequently familial neoplasm, arising from the glandular epithelium of the stomach, small intestine, biliary tract, colon, and rectum. It is a polypoid or flat circumscribed lesion. Morphologically, it is characterized by a proliferation of neoplastic glandular cells and it is associated with dysplasia. According to the growth pattern, it may be classified as tubular, villous, or tubulovillous. The dysplasia is classified as mild, moderate, or severe. The frequency of malignant transformation depends on the size of the lesion and the degree of dysplasia. Larger adenomas with severe dysplastic changes (sometimes called carcinoma in situ) carry a higher risk of progressing to invasive adenocarcinoma. Gastrointestinal adenomas may present as solitary or multifocal lesions. Familial adenomas tend to be multifocal and carry a higher risk of malignant transformation." ;
rdfs:subClassOf obo:MONDO_0004972 , obo:MONDO_0021223 .
obo:HP_0012592 a rdfs:Class ;
rdfs:label "Albuminuria" ;
rdfs:comment "Increased concentration of albumin in the urine." ;
rdfs:subClassOf obo:HP_0020129 .
obo:MONDO_0005278 a rdfs:Class ;
rdfs:label "serous adenocarcinoma" ;
rdfs:comment "An adenocarcinoma that is characterized by the presence of papillary patterns and cellular budding. Psammoma bodies may be present. Representative examples include cervical serous adenocarcinoma, endometrial serous adenocarcinoma, ovarian serous adenocarcinoma, and primary peritoneal serous adenocarcinoma." ;
rdfs:subClassOf obo:MONDO_0004970 .
obo:MONDO_0002311 a rdfs:Class ;
rdfs:label "retinal vascular disorder" ;
rdfs:comment "Retinal damage resulting from diminished blood flow/oxygenation due to abnormalities of the retinal vessels. Causes include hypertension, diabetes, thrombosis, embolism, and hemorrhage." ;
rdfs:subClassOf obo:MONDO_0005283 , obo:MONDO_0005552 , obo:MONDO_0043218 .
obo:ECTO_9002037 a rdfs:Class ;
rdfs:label "exposure to phytoestrogen" ;
rdfs:comment "An exposure to phytoestrogen." ;
rdfs:subClassOf obo:ECTO_9000010 .
obo:ECTO_9002138 a rdfs:Class ;
rdfs:label "exposure to glyphosate" ;
rdfs:comment "An exposure to glyphosate." ;
rdfs:subClassOf obo:ECTO_0000371 , obo:ECTO_9000190 , obo:ECTO_9001227 .
obo:MONDO_0002480 a rdfs:Class ;
rdfs:label "endometrioid tumor" ;
rdfs:comment "A benign, borderline, or malignant epithelial tumor of the female reproductive system characterized by the presence of glands and/or cysts lined by neoplastic cells that resemble endometrial cells." ;
rdfs:subClassOf obo:MONDO_0005626 , obo:MONDO_0021148 .
obo:MONDO_0006513 a rdfs:Class ;
rdfs:label "estrogen-receptor negative breast cancer" ;
rdfs:comment "A subtype of breast cancer that is estrogen-receptor negative" ;
rdfs:subClassOf obo:MONDO_0006116 .
obo:ECTO_9001630 a rdfs:Class ;
rdfs:label "exposure to endocrine disruptor" ;
rdfs:comment "An exposure to endocrine disruptor." ;
rdfs:subClassOf obo:ECTO_0000509 .
obo:MONDO_0020248 a rdfs:Class ;
rdfs:label "vitreoretinal degeneration" ;
rdfs:subClassOf obo:MONDO_0001377 , obo:MONDO_0020246 .
obo:MONDO_0001612 a rdfs:Class ;
rdfs:label "carotid stenosis" ;
rdfs:comment "A narrowing of the carotid artery lumen. It is usually caused by the formation of an atherosclerotic plaque. Symptoms are usually present when there is severe narrowing or obstruction of the arterial lumen and manifest as ischemic cerebrovascular accidents." ;
rdfs:subClassOf obo:MONDO_0005269 .
obo:MONDO_0000812 a rdfs:Class ;
rdfs:label "vertebral column disorder" ;
rdfs:comment "A disease involving the vertebral column." ;
rdfs:subClassOf obo:MONDO_0005172 .
obo:MONDO_0003406 a rdfs:Class ;
rdfs:label "sleep-wake disorder" ;
rdfs:comment "Abnormal sleep-wake schedule or pattern associated with the circadian rhythm which affect the length, timing, and/or rigidity of the sleep-wake cycle relative to the day-night cycle. These can include dyssomnias such as circadian rhythm disorders, hypersomnia, and sleep apnea and parasomnias such as bruxism and rapid eye movement sleep disorder." ;
rdfs:subClassOf obo:MONDO_0100081 .
obo:HP_0040195 a rdfs:Class ;
rdfs:label "Decreased head circumference" ;
rdfs:comment "An abnormally reduced head circumference in a growing child. Head circumference is measured with a nonelastic tape and comprises the distance from above the eyebrows and ears and around the back of the head. The measured HC is then plotted on an appropriate growth chart. Microcephaly is defined as a head circumference (HC) that is great than two standard deviations below the mean of age- and gender-matched population based samples. Severe microcephaly is defined with an HC that is three standard deviations below the mean." ;
rdfs:subClassOf obo:HP_0000240 .
obo:MONDO_0005148 a rdfs:Class ;
rdfs:label "type 2 diabetes mellitus" ;
rdfs:comment "A type of diabetes mellitus that is characterized by insulin resistance or desensitization and increased blood glucose levels. This is a chronic disease that can develop gradually over the life of a patient and can be linked to both environmental factors and heredity." ;
rdfs:subClassOf obo:MONDO_0005015 .
obo:MONDO_0006209 a rdfs:Class ;
rdfs:label "fibroblastic neoplasm" ;
rdfs:comment "A benign, intermediate, or malignant mesenchymal neoplasm characterized by the presence of neoplastic fibroblasts." ;
rdfs:subClassOf obo:MONDO_0002616 , obo:MONDO_0021581 .
obo:MONDO_0005267 a rdfs:Class ;
rdfs:label "heart disorder" ;
rdfs:comment "A disease involving the heart and/or pericardium." ;
rdfs:subClassOf obo:MONDO_0004995 .
obo:MONDO_0021839 a rdfs:Class ;
rdfs:label "spirochaetales infections" ;
rdfs:comment "Infections with bacteria of the order SPIROCHAETALES." ;
rdfs:subClassOf obo:MONDO_0005113 .
obo:MONDO_0019004 a rdfs:Class ;
rdfs:label "kidney Wilms tumor" ;
rdfs:comment "An embryonal pediatric tumor of the kidney which may also be seen rarely in adults. The peak incidence of Wilms tumor is between the second and fifth year of life. Microscopically, it is composed of a mixture of cellular elements (blastemal, stromal, and epithelial). The most common sites of metastasis include the regional lymph nodes, lungs, and liver." ;
rdfs:subClassOf obo:MONDO_0002367 , obo:MONDO_0006058 .
obo:MONDO_0021925 a rdfs:Class ;
rdfs:label "tracheobronchitis" ;
rdfs:comment "Inflammation of the tracheobronchial tree." ;
rdfs:subClassOf obo:MONDO_0000270 , obo:MONDO_0021166 .
obo:ECTO_6000014 a rdfs:Class ;
rdfs:label "exposure to smoking cessation" ;
rdfs:comment "An exposure event involving Smoking Cessation" ;
rdfs:subClassOf obo:ECTO_6000016 .
obo:MONDO_0023370 a rdfs:Class ;
rdfs:label "neoplastic disease or syndrome" ;
rdfs:comment "Either an isolated neoplasm or a syndrome with neoplasm as a major feature." ;
rdfs:subClassOf obo:MONDO_0045024 .
obo:MONDO_0005133 a rdfs:Class ;
rdfs:label "endometriosis" ;
rdfs:comment "The growth of functional endometrial tissue in anatomic sites outside the uterine body. It most often occurs in the pelvic organs." ;
rdfs:subClassOf obo:MONDO_0000931 .
obo:MONDO_0005231 a rdfs:Class ;
rdfs:label "hepatitis C virus infection" ;
rdfs:comment "A viral infection caused by the hepatitis C virus." ;
rdfs:subClassOf obo:MONDO_0006011 .
obo:MONDO_0024355 a rdfs:Class ;
rdfs:label "respiratory tract infectious disorder" ;
rdfs:comment "Invasion of the host RESPIRATORY SYSTEM by microorganisms, usually leading to pathological processes or diseases." ;
rdfs:subClassOf obo:MONDO_0005087 , obo:MONDO_0005550 .
obo:MONDO_0850271 a rdfs:Class ;
rdfs:label "myeloid leukemia associated with down syndrome" ;
rdfs:comment "An acute megakaryocytic leukemia occurring in children with Down syndrome and that has material basis in mutation in the GATA1 gene." ;
rdfs:subClassOf obo:MONDO_0018872 .
obo:HP_0002637 a rdfs:Class ;
rdfs:label "Cerebral ischemia" ;
rdfs:comment "Restriction of arterial blood supply to the brain associated with insufficient oxygenation to support the metabolic requirements of the tissue." ;
rdfs:subClassOf obo:HP_0033401 .
obo:HP_0002625 a rdfs:Class ;
rdfs:label "Deep venous thrombosis" ;
rdfs:comment "Formation of a blot clot in a deep vein. The clot often blocks blood flow, causing swelling and pain. The deep veins of the leg are most often affected." ;
rdfs:subClassOf obo:HP_0004936 .
obo:MONDO_0011382 a rdfs:Class ;
rdfs:label "sickle cell disease" ;
rdfs:comment "Sickle cell anemias are chronic hemolytic diseases that may induce three types of acute accidents: severe anemia, severe bacterial infections, and ischemic vasoocclusive accidents (VOA) caused by sickle-shaped red blood cells obstructing small blood vessels and capillaries. Many diverse complications can occur." ;
rdfs:subClassOf obo:MONDO_0006025 , obo:MONDO_0019050 .
obo:HP_0000505 a rdfs:Class ;
rdfs:label "Visual impairment" ;
rdfs:comment "Visual impairment (or vision impairment) is vision loss (of a person) to such a degree as to qualify as an additional support need through a significant limitation of visual capability resulting from either disease, trauma, or congenital or degenerative conditions that cannot be corrected by conventional means, such as refractive correction, medication, or surgery." ;
rdfs:subClassOf obo:HP_0000504 .
obo:GO_0016301 a rdfs:Class ;
rdfs:label "kinase activity" ;
rdfs:comment "Catalysis of the transfer of a phosphate group, usually from ATP, to a substrate molecule." ;
rdfs:subClassOf obo:GO_0003674 .
obo:MONDO_0015486 a rdfs:Class ;
rdfs:label "keratoconus" ;
rdfs:comment "A degenerative, structural disorder of the eye, characterized by a cone-shaped protrusion of the cornea. It may lead to visual disturbances." ;
rdfs:subClassOf obo:MONDO_0000942 , obo:MONDO_0003847 , obo:MONDO_0100581 .
obo:ECTO_9000281 a rdfs:Class ;
rdfs:label "exposure to DDT" ;
rdfs:comment "An exposure to DDT." ;
rdfs:subClassOf obo:ECTO_0000163 , obo:ECTO_9001534 .
obo:MONDO_0021225 a rdfs:Class ;
rdfs:label "uvea neoplasm" ;
rdfs:comment "A neoplasm (disease) that involves the uvea." ;
rdfs:subClassOf obo:MONDO_0002661 , obo:MONDO_0021220 .
obo:MONDO_0006061 a rdfs:Class ;
rdfs:label "cervical artery dissection" ;
rdfs:comment "A tear within the wall of any of the arteries of the neck (carotid artery or vertebral artery) and that allows blood to separate the wall layers. By separating a portion of the wall of the artery (a layer of the Tunica intima or tunica media), a dissection creates two lumens or passages within the vessel, the native or true lumen, and the \"false lumen\" created by the new space within the wall of the artery." ;
rdfs:subClassOf obo:MONDO_0000473 .
obo:MONDO_0003220 a rdfs:Class ;
rdfs:label "gallbladder carcinoma" ;
rdfs:comment "A carcinoma that arises from epithelial cells of the gall bladder" ;
rdfs:subClassOf obo:MONDO_0005411 , obo:MONDO_0006181 .
obo:MONDO_0000510 a rdfs:Class ;
rdfs:label "synucleinopathy" ;
rdfs:comment "A neurodegenerative disease that is characterized by the abnormal accumulation of aggregates of alpha-synuclein protein in neurons, nerve fibers or glial cells. [url:http://en.wikipedia.org/wiki/Synucleinopathies ]" ;
rdfs:subClassOf obo:MONDO_0005559 , obo:MONDO_0021179 .
obo:MONDO_0015356 a rdfs:Class ;
rdfs:label "hereditary neoplastic syndrome" ;
rdfs:comment "The inherited predisposition toward getting a tumor." ;
rdfs:subClassOf obo:MONDO_0003847 , obo:MONDO_0020573 , obo:MONDO_0021058 .
obo:MONDO_0020683 a rdfs:Class ;
rdfs:label "acute disease" ;
rdfs:comment "Disease having a short and relatively severe course." ;
rdfs:subClassOf obo:MONDO_0700096 .
obo:MONDO_0005138 a rdfs:Class ;
rdfs:label "lung carcinoma" ;
rdfs:comment "A carcinoma that arises from epithelial cells of the lung" ;
rdfs:subClassOf obo:MONDO_0004993 , obo:MONDO_0008903 .
obo:MONDO_0003225 a rdfs:Class ;
rdfs:label "bone marrow disorder" ;
rdfs:comment "Any disease of the bone marrow." ;
rdfs:subClassOf obo:MONDO_0005046 , obo:MONDO_0005172 , obo:MONDO_0005570 .
obo:ECTO_9002127 a rdfs:Class ;
rdfs:label "exposure to sex hormone" ;
rdfs:comment "An exposure to sex hormone." ;
rdfs:subClassOf obo:ECTO_0000516 .
obo:MONDO_0018438 a rdfs:Class ;
rdfs:label "eosinophilic gastrointestinal disease" ;
rdfs:subClassOf obo:MONDO_0005020 .
obo:MONDO_0004979 a rdfs:Class ;
rdfs:label "asthma" ;
rdfs:comment "A bronchial disease that is characterized by chronic inflammation and narrowing of the airways, which is caused by a combination of environmental and genetic factors resulting in recurring periods of wheezing (a whistling sound while breathing), chest tightness, shortness of breath, mucus production and coughing. The symptoms appear due to a variety of triggers such as allergens, irritants, respiratory infections, weather changes, exercise, stress, reflux disease, medications, foods and emotional anxiety." ;
rdfs:subClassOf obo:MONDO_0001358 .
obo:MONDO_0001933 a rdfs:Class ;
rdfs:label "endocrine pancreas disorder" ;
rdfs:comment "A disease involving the endocrine pancreas." ;
rdfs:subClassOf obo:MONDO_0002356 .
obo:ECTO_6000000 a rdfs:Class ;
rdfs:label "exposure to behavior" ;
rdfs:comment "An exposure event involving Activity" ;
rdfs:subClassOf obo:ExO_0000002 .
obo:MONDO_0002175 a rdfs:Class ;
rdfs:label "degeneration of macula and posterior pole" ;
rdfs:subClassOf obo:MONDO_0003004 .
obo:MONDO_0015547 a rdfs:Class ;
rdfs:label "hereditary dementia" ;
rdfs:comment "An instance of dementia that is caused by an inherited genomic modification in an individual." ;
rdfs:subClassOf obo:MONDO_0001627 , obo:MONDO_0003847 .
obo:MONDO_0021138 a rdfs:Class ;
rdfs:label "bone marrow cancer" ;
rdfs:comment "Malignant neoplasms that either originate from the bone marrow (e.g. myeloid leukemias) or involve the bone marrow as secondary-metastatic tumors (e.g. metastatic carcinomas to the bone marrow). --2003" ;
rdfs:subClassOf obo:MONDO_0000621 , obo:MONDO_0002129 , obo:MONDO_0005374 .
obo:MONDO_0021079 a rdfs:Class ;
rdfs:label "childhood neoplasm" ;
rdfs:comment "A benign or malignant neoplasm arising during childhood." ;
rdfs:subClassOf obo:MONDO_0005070 .
obo:MONDO_0021357 a rdfs:Class ;
rdfs:label "tumor of salivary gland" ;
rdfs:comment "A neoplasm (disease) that involves the saliva-secreting gland." ;
rdfs:subClassOf obo:MONDO_0001142 , obo:MONDO_0005586 , obo:MONDO_0021223 .
obo:MONDO_0044348 a rdfs:Class ;
rdfs:label "hemoglobinopathy" ;
rdfs:subClassOf obo:MONDO_0044347 .
obo:MONDO_0021057 a rdfs:Class ;
rdfs:label "classic or attenuated familial adenomatous polyposis" ;
rdfs:comment "An inherited diseases haracterized by the development of adenomas in the rectum and colon; classified into classic FAP and attenuated FAP." ;
rdfs:subClassOf obo:MONDO_0015185 .
obo:MONDO_0021220 a rdfs:Class ;
rdfs:label "eye neoplasm" ;
rdfs:comment "A neoplasm (disease) that involves the eye." ;
rdfs:subClassOf obo:MONDO_0005328 , obo:MONDO_0005586 .
obo:MONDO_0005192 a rdfs:Class ;
rdfs:label "exocrine pancreatic carcinoma" ;
rdfs:comment "A carcinoma that arises from epithelial cells of the exocrine pancreas" ;
rdfs:subClassOf obo:MONDO_0002116 , obo:MONDO_0006181 .
obo:MONDO_0008608 a rdfs:Class ;
rdfs:label "Down syndrome" ;
rdfs:comment "Down syndrome is a chromosomal abnormality caused by the presence of a third (partial or total) copy of the chromosome 21 genetic material and that is characterized by variable intellectual disability, muscular hypotonia, and joint laxity, often associated with a characteristic facial dysmorphism and various anomalies such as cardiac, gastrointestinal, or endocrine defects." ;
rdfs:subClassOf obo:MONDO_0700124 .
obo:MONDO_0005260 a rdfs:Class ;
rdfs:label "autism" ;
rdfs:comment "Persistent deficits in social interaction and communication and interaction as well as a markedly restricted repertoire of activity and interest as well as repetitive patterns of behavior." ;
rdfs:subClassOf obo:MONDO_0005258 .
obo:MONDO_0021368 a rdfs:Class ;
rdfs:label "neoplasm of major salivary gland" ;
rdfs:comment "A neoplasm (disease) that involves the major salivary gland." ;
rdfs:subClassOf obo:MONDO_0021357 .
obo:MONDO_0002260 a rdfs:Class ;
rdfs:label "hidradenitis" ;
rdfs:comment "An inflammatory disease involving a pathogenic inflammatory response in the apocrine sweat gland." ;
rdfs:subClassOf obo:MONDO_0021166 , obo:MONDO_0024467 .
obo:HP_5210013 a rdfs:Class ;
rdfs:label "Unusual Streptococcus pyogenes infection" ;
rdfs:comment "Increased susceptibility to Streptococcus pyogenes infections as manifested by recurrent or severe/invasive infection with Streptococcus pyogenes, or by Streptococcus pyogenes infection occurring in an unusual anatomical location." ;
rdfs:subClassOf obo:HP_5210009 .
obo:MONDO_0004643 a rdfs:Class ;
rdfs:label "myeloid leukemia" ;
rdfs:comment "A clonal proliferation of myeloid cells and their precursors in the bone marrow, peripheral blood, and spleen. When the proliferating cells are immature myeloid cells and myeloblasts, it is called acute myeloid leukemia. When the proliferating myeloid cells are neutrophils, it is called chronic myelogenous leukemia." ;
rdfs:subClassOf obo:MONDO_0005059 , obo:MONDO_0020076 .
obo:MONDO_0020283 a rdfs:Class ;
rdfs:label "uveitis" ;
rdfs:comment "An inflammatory process affecting a part of or the entire uvea. Causes include inflammatory agents (e.g., herpes simplex, herpes zoster, leptospirosis) and systemic diseases (e.g., inflammatory bowel disease, multiple sclerosis, systemic lupus erythematosus, ankylosing spondylitis). Patients present with pain and redness in the eye, light sensitivity, and blurred and decreased vision." ;
rdfs:subClassOf obo:MONDO_0002661 , obo:MONDO_0021166 .
obo:MONDO_0005306 a rdfs:Class ;
rdfs:label "ankylosing spondylitis" ;
rdfs:comment "An autoimmune chronic inflammatory disorder characterized by inflammation in the vertebral joints of the spine and sacroiliac joints. It predominantly affects young males. Patients present with stiffness and pain in the spine." ;
rdfs:subClassOf obo:MONDO_0003937 , obo:MONDO_0005095 , obo:MONDO_0008383 , obo:MONDO_0037847 .
obo:MONDO_0003792 a rdfs:Class ;
rdfs:label "ovarian carcinosarcoma" ;
rdfs:comment "A highly aggressive malignant neoplasm arising from the ovary. Morphologically, it is a high grade tumor, composed of carcinomatous and sarcomatous elements." ;
rdfs:subClassOf obo:MONDO_0002928 , obo:MONDO_0003812 , obo:MONDO_0005140 .
obo:HP_0005162 a rdfs:Class ;
rdfs:label "Abnormal left ventricular function" ;
rdfs:comment "Inability of the left ventricle to perform its normal physiologic function. Failure is either due to an inability to contract the left ventricle or the inability to relax completely and fill with blood during diastole." ;
rdfs:subClassOf obo:HP_0030872 .
obo:MONDO_0001318 a rdfs:Class ;
rdfs:label "functional gastric disease" ;
rdfs:subClassOf obo:MONDO_0004298 .
obo:MONDO_0005341 a rdfs:Class ;
rdfs:label "skin basal cell carcinoma" ;
rdfs:comment "The most frequently seen skin cancer. It arises from basal cells of the epidermis and pilosebaceous units. Clinically it is divided into the following types: nodular, ulcerative, superficial, multicentric, erythematous, and sclerosing or morphea-like. More than 95% of these carcinomas occur in patients over 40. They develop on hair-bearing skin, most commonly on sun-exposed areas. Approximately 85% are found on the head and neck and the remaining 15% on the trunk and extremities. Basal cell carcinoma usually grows in a slow and indolent fashion. However, if untreated, the tumor may invade the subcutaneous fat, skeletal muscle and bone. Distant metastases are rare. Excision, curettage and irradiation cure most basal cell carcinomas." ;
rdfs:subClassOf obo:MONDO_0002656 , obo:MONDO_0020804 .
obo:MONDO_0004986 a rdfs:Class ;
rdfs:label "urinary bladder carcinoma" ;
rdfs:comment "A carcinoma that arises from epithelial cells of the urinary bladder" ;
rdfs:subClassOf obo:MONDO_0001187 , obo:MONDO_0004993 .
obo:MONDO_0007763 a rdfs:Class ;
rdfs:label "nonpapillary renal cell carcinoma" ;
rdfs:subClassOf obo:MONDO_0005086 .
obo:HP_0001607 a rdfs:Class ;
rdfs:label "Subglottic stenosis" ;
rdfs:subClassOf obo:HP_0025423 .
obo:MONDO_0015667 a rdfs:Class ;
rdfs:label "acute myeloid leukemia by FAB classification" ;
rdfs:comment "Acute myeloid leukemias that do not fulfill the criteria for inclusion in the group of acute myeloid leukemias which have recurrent genetic abnormalities or myelodysplastic changes, or are therapy-related. This category includes entities classified according to the French-American-British classification scheme." ;
rdfs:subClassOf obo:MONDO_0018874 .
obo:HP_0006536 a rdfs:Class ;
rdfs:label "Airway obstruction" ;
rdfs:comment "Obstruction of conducting airways of the lung." ;
rdfs:subClassOf obo:HP_0002795 .
obo:ECTO_9000409 a rdfs:Class ;
rdfs:label "exposure to salt" ;
rdfs:comment "An exposure to salt." ;
rdfs:subClassOf obo:ECTO_0000231 .
obo:MONDO_0001409 a rdfs:Class ;
rdfs:label "esophagitis" ;
rdfs:comment "An acute or chronic inflammatory disease affecting the esophageal wall." ;
rdfs:subClassOf obo:MONDO_0003749 , obo:MONDO_0021166 .
obo:MONDO_0003749 a rdfs:Class ;
rdfs:label "esophageal disorder" ;
rdfs:comment "A non-neoplastic or neoplastic disorder that affects the esophagus. Representative examples of non-neoplastic disorders include esophagitis and esophageal ulcer. Representative examples of neoplastic disorders include carcinomas, lymphomas, and melanomas." ;
rdfs:subClassOf obo:MONDO_0044991 .
obo:MONDO_0005283 a rdfs:Class ;
rdfs:label "retinal disorder" ;
rdfs:comment "Any disease or disorder of the retina." ;
rdfs:subClassOf obo:MONDO_0005071 , obo:MONDO_0005328 .
obo:MONDO_0002263 a rdfs:Class ;
rdfs:label "female reproductive system disorder" ;
rdfs:comment "A disease involving the female reproductive system." ;
rdfs:subClassOf obo:MONDO_0005039 .
obo:MONDO_0019064 a rdfs:Class ;
rdfs:label "hereditary spastic paraplegia" ;
rdfs:comment "Hereditary spastic paraplegias (HSP) comprise a genetically and clinically heterogeneous group of neurodegenerative disorders characterized by progressive spasticity and hyperreflexia of the lower limbs." ;
rdfs:subClassOf obo:MONDO_0003757 , obo:MONDO_0024237 , obo:MONDO_0100546 .
obo:MONDO_1010185 a rdfs:Class ;
rdfs:label "transplant rejection" ;
rdfs:comment "A disease related to transplantation that occurs when transplant tissue is rejected by the recipient's immune system, which destroys the transplanted tissue." ;
rdfs:subClassOf obo:MONDO_0700220 .
obo:MONDO_0005447 a rdfs:Class ;
rdfs:label "testicular cancer" ;
rdfs:comment "A primary or metastatic malignant neoplasm that affects the testis. Representative examples include seminoma, embryonal carcinoma, sarcoma, leukemia, and lymphoma." ;
rdfs:subClassOf obo:MONDO_0005836 , obo:MONDO_0021348 .
obo:MONDO_0000724 a rdfs:Class ;
rdfs:label "specific language impairment" ;
rdfs:comment "A language disorder characterized by difficulty in language acquisition despite otherwise normal development and in the absence of any obvious explanatory factors." ;
rdfs:subClassOf obo:MONDO_0004750 , obo:MONDO_0100545 .
obo:HP_5200430 a rdfs:Class ;
rdfs:label "Abnormal psychotic pattern" ;
rdfs:comment "Any abnormal pattern of psychotic experiences, where an individual has significant disturbances in their thoughts, perceptions, emotions, and behavior, resulting in a loss of touch with reality." ;
rdfs:subClassOf obo:HP_5200423 .
obo:MONDO_0003780 a rdfs:Class ;
rdfs:label "T-cell immunodeficiency" ;
rdfs:comment "A broad classification of disorders that affect the cell-mediated aspect of the immune response. Circulating numbers of T lymphocytes are decreased or ineffective." ;
rdfs:subClassOf obo:MONDO_0021094 .
obo:MONDO_0021040 a rdfs:Class ;
rdfs:label "pancreatic neoplasm" ;
rdfs:comment "A benign or malignant neoplasm involving the pancreas." ;
rdfs:subClassOf obo:MONDO_0002356 , obo:MONDO_0021223 .
obo:MONDO_0016542 a rdfs:Class ;
rdfs:label "IL10-related early-onset inflammatory bowel disease" ;
rdfs:comment "A rare immune dysregulation disease with immunodeficiency characterized by severe, progressive infantile onset inflammatory bowel disease with pancolitis, perianal disease (ulceration, fistulae), recurrent respiratory, genitourinary and cutaneous infections, arthritis and a high risk of B-cell lymphoma." ;
rdfs:subClassOf obo:MONDO_0003778 , obo:MONDO_0005265 , obo:MONDO_0005554 , obo:MONDO_0023603 .
obo:MONDO_0020590 a rdfs:Class ;
rdfs:label "mycobacterial infectious disease" ;
rdfs:comment "Infection due to organisms from the genus Mycobacteria." ;
rdfs:subClassOf obo:MONDO_0005113 .
obo:MONDO_0013153 a rdfs:Class ;
rdfs:label "inflammatory bowel disease 28" ;
rdfs:comment "Any inflammatory bowel disease in which the cause of the disease is a mutation in the IL10RA gene." ;
rdfs:subClassOf obo:MONDO_0016542 .
obo:MONDO_0018155 a rdfs:Class ;
rdfs:label "lateral sclerosis" ;
rdfs:comment "Primary lateral sclerosis (PLS) is an idiopathic non-familial motor neuron disease characterized by slowly progressive upper motor neuron dysfunction leading to spasticity, mild weakness in voluntary muscle movement, hyperreflexia, and loss of motor speech production." ;
rdfs:subClassOf obo:MONDO_0024257 .
obo:MONDO_0005294 a rdfs:Class ;
rdfs:label "peripheral vascular disease" ;
rdfs:comment "Any disorder affecting blood flow through the veins or arteries outside of the heart." ;
rdfs:subClassOf obo:MONDO_0005385 .
obo:MONDO_0021068 a rdfs:Class ;
rdfs:label "ovarian neoplasm" ;
rdfs:comment "A benign, borderline, or malignant neoplasm involving the ovary." ;
rdfs:subClassOf obo:MONDO_0005558 , obo:MONDO_0021148 .
obo:HP_0002011 a rdfs:Class ;
rdfs:label "Morphological central nervous system abnormality" ;
rdfs:comment "A structural abnormality of the central nervous system." ;
rdfs:subClassOf obo:HP_0012639 .
obo:MONDO_0004867 a rdfs:Class ;
rdfs:label "upper respiratory tract disorder" ;
rdfs:comment "A disease involving the upper respiratory tract." ;
rdfs:subClassOf obo:MONDO_0005087 .
obo:MONDO_0021351 a rdfs:Class ;
rdfs:label "neoplasm of neck" ;
rdfs:comment "A neoplasm (disease) that involves the neck." ;
rdfs:subClassOf obo:MONDO_0005586 .
obo:MONDO_1040015 a rdfs:Class ;
rdfs:label "infectious disease with sepsis" ;
rdfs:comment "An infectious disease characterized by life-threatening organ dysfunction due to a dysreguated host response." ;
rdfs:subClassOf obo:MONDO_0005550 .
obo:HP_0003419 a rdfs:Class ;
rdfs:label "Low back pain" ;
rdfs:comment "An unpleasant sensation characterized by physical discomfort (such as pricking, throbbing, or aching) localized to the lower back." ;
rdfs:subClassOf obo:HP_0003418 .
obo:MONDO_0016752 a rdfs:Class ;
rdfs:label "benign peripheral nerve sheath tumor" ;
rdfs:subClassOf obo:MONDO_0016749 .
obo:MONDO_0021636 a rdfs:Class ;
rdfs:label "astrocytic tumor" ;
rdfs:comment "A glial tumor of the brain or spinal cord showing astrocytic differentiation. It includes the following clinicopathological entities: pilocytic astrocytoma, diffuse astrocytoma, anaplastic astrocytoma, pleomorphic xanthoastrocytoma, subependymal giant cell astrocytoma, and glioblastoma." ;
rdfs:subClassOf obo:MONDO_0021042 .
obo:MONDO_0003847 a rdfs:Class ;
rdfs:label "hereditary disease" ;
rdfs:comment "A disease that is caused by genetic modifications where those modifications are inherited from a parent's genome." ;
rdfs:subClassOf obo:MONDO_7770009 .
obo:MONDO_0004952 a rdfs:Class ;
rdfs:label "Hodgkins lymphoma" ;
rdfs:comment "A heterogeneous group of malignant lymphoid neoplasms of B-cell origin characterized histologically by the presence of Hodgkin and Reed-Sternberg (HRS) cells in the vast majority of cases. There are two distinct subtypes: nodular lymphocyte predominant Hodgkin lymphoma and classical Hodgkin lymphoma. Hodgkin lymphoma involves primarily lymph nodes." ;
rdfs:subClassOf obo:MONDO_0005062 , obo:MONDO_0017343 .
obo:MONDO_0018882 a rdfs:Class ;
rdfs:label "vasculitis" ;
rdfs:comment "Vasculitis represents a clinically heterogenous group of diseases of multifactorial etiology characterized by inflammation of either large-sized vessels (large-vessel vasculitis, e.g. Giant-cell arteritis and Takayasu arteritis), medium-sized vessels (medium-vessel vasculitis e.g. polyarteritis nodosa and Kawasaki disease), or small-sized vessels (small-vessel vasculitis, e.g. granulomatosis with polyangiitis, microscopic polyangiitis, immunoglobulin A vasculitis, and cutaneous leukocytoclastic angiitis). Vasculitis occurs at any age, may be acute or chronic, and manifests with general symptoms such as fever, weight loss and fatigue, as well as more specific clinical signs depending on the type of vessels and organs affected. The degree of severity is variable, ranging from life or sight threatening disease (e.g. Behcet disease) to relatively minor skin disease." ;
rdfs:subClassOf obo:MONDO_0005385 , obo:MONDO_0021166 .
obo:MONDO_0000873 a rdfs:Class ;
rdfs:label "lymphoblastic lymphoma" ;
rdfs:comment "A lymphoma composed of immature small to medium-sized precursor lymphoid cells (lymphoblasts). It includes the B- and T-cell lymphoblastic lymphoma." ;
rdfs:subClassOf obo:MONDO_0003538 , obo:MONDO_0018908 .
obo:ECTO_9001687 a rdfs:Class ;
rdfs:label "exposure to micronutrient" ;
rdfs:comment "An exposure to micronutrient." ;
rdfs:subClassOf obo:ECTO_9001695 .
obo:ECTO_6000029 a rdfs:Class ;
rdfs:label "exposure to tobacco smoking" ;
rdfs:comment "An exposure event involving Tobacco Smoking" ;
rdfs:subClassOf obo:ECTO_6000013 , obo:ECTO_6000041 .
obo:MONDO_0015760 a rdfs:Class ;
rdfs:label "T-cell non-Hodgkin lymphoma" ;
rdfs:comment "A non-Hodgkin lymphoma of T-cell lineage. It includes the T lymphoblastic lymphoma and the mature T- and NK-cell lymphomas. -- 2003" ;
rdfs:subClassOf obo:MONDO_0018908 .
obo:ECTO_1000034 a rdfs:Class ;
rdfs:label "exposure to farm" ;
rdfs:comment "A exposure event involving the interaction of an exposure receptor to farm." ;
rdfs:subClassOf obo:ECTO_0600000 .
obo:MONDO_0005374 a rdfs:Class ;
rdfs:label "bone marrow neoplasm" ;
rdfs:comment "Neoplasms that affect the bone marrow. Such neoplasms may arise in the bone marrow (e.g. myeloid leukemias) or may involve the bone marrow as secondary, metastatic tumors (e.g. metastatic carcinomas to the bone marrow)." ;
rdfs:subClassOf obo:MONDO_0002334 , obo:MONDO_0003225 .
obo:MONDO_0007576 a rdfs:Class ;
rdfs:label "esophageal cancer" ;
rdfs:comment "A primary or metastatic malignant neoplasm involving the esophagus." ;
rdfs:subClassOf obo:MONDO_0002516 , obo:MONDO_0021355 .
obo:MONDO_7770009 a rdfs:Class ;
rdfs:label "disease of genetic or genomic mechanism" ;
rdfs:comment "A grouping class for human diseases caused by genetic or genomic alterations, including chromosomal abnormalities and heritable mutations." ;
rdfs:subClassOf obo:MONDO_7770008 .
obo:ECTO_0001152 a rdfs:Class ;
rdfs:label "exposure to organochlorine compound" ;
rdfs:comment "An exposure to organochlorine compound." ;
rdfs:subClassOf obo:ECTO_0000135 , obo:ECTO_9000077 .
obo:ECTO_9002355 a rdfs:Class ;
rdfs:label "exposure to arsenic atom" ;
rdfs:comment "An exposure to arsenic atom." ;
rdfs:subClassOf obo:ECTO_9001631 .
obo:ECTO_9001647 a rdfs:Class ;
rdfs:label "exposure to antioxidant" ;
rdfs:comment "An exposure to antioxidant." ;
rdfs:subClassOf obo:ECTO_0000487 .
obo:MONDO_0005627 a rdfs:Class ;
rdfs:label "head and neck cancer" ;
rdfs:comment "A primary or metastatic malignant neoplasm affecting the head and neck. Representative examples include oral cavity squamous cell carcinoma, laryngeal squamous cell carcinoma, and salivary gland carcinoma." ;
rdfs:subClassOf obo:MONDO_0004992 , obo:MONDO_0005586 .
obo:ECTO_0000931 a rdfs:Class ;
rdfs:label "exposure to environmental contaminant" ;
rdfs:comment "An exposure to environmental contaminant." ;
rdfs:subClassOf obo:ECTO_0000487 .
obo:MONDO_0004975 a rdfs:Class ;
rdfs:label "Alzheimer disease" ;
rdfs:comment "A progressive, neurodegenerative disease characterized by loss of function and death of nerve cells in several areas of the brain leading to loss of cognitive function such as memory and language." ;
rdfs:subClassOf obo:MONDO_0001627 , obo:MONDO_0005574 .
obo:MONDO_0021632 a rdfs:Class ;
rdfs:label "primary brain neoplasm" ;
rdfs:subClassOf obo:MONDO_0021211 .
obo:MONDO_7770011 a rdfs:Class ;
rdfs:label "disease by molecular mechanism" ;
rdfs:comment "A grouping class for human diseases classified by their underlying molecular or pathophysiological mechanism, such as protein aggregation, ion channel dysfunction, or signal transduction disruption." ;
rdfs:subClassOf obo:MONDO_7770007 .
obo:MONDO_0043693 a rdfs:Class ;
rdfs:label "alcoholic liver disease" ;
rdfs:comment "A disorder caused by damage to the liver parenchyma due to alcohol consumption. It may present with an acute onset or follow a chronic course, leading to cirrhosis." ;
rdfs:subClassOf obo:MONDO_0005154 , obo:MONDO_0021699 .
obo:MONDO_0021353 a rdfs:Class ;
rdfs:label "tumor of uterus" ;
rdfs:comment "A neoplasm (disease) that involves the uterus." ;
rdfs:subClassOf obo:MONDO_0002654 , obo:MONDO_0021148 .
obo:MONDO_0005853 a rdfs:Class ;
rdfs:label "malignant mixed neoplasm" ;
rdfs:comment "A malignant neoplasm composed of a carcinomatous epithelial component and a sarcomatous mesenchymal component. Representative examples include malignant mixed mesodermal (Mullerian) tumor of the female reproductive system and carcinosarcoma of the salivary gland and the lung." ;
rdfs:subClassOf obo:MONDO_0004992 , obo:MONDO_0021043 .
obo:MONDO_0021699 a rdfs:Class ;
rdfs:label "alcohol-induced disorders" ;
rdfs:comment "Disorders stemming from the misuse and abuse of alcohol." ;
rdfs:subClassOf obo:MONDO_0021698 .
obo:MONDO_0019496 a rdfs:Class ;
rdfs:label "neuroendocrine neoplasm" ;
rdfs:comment "Endocrine tumors, also referred to as neuroendocrine tumors (NETs), are defined by a common phenotype which is characterized by the expression of general markers (neuron specific enolase, chromogranin, synaptophysin) and hormone secretion products. These tumors may be localized in any part of the body and are generally discovered in non-specific situations, i.e. not immediately suggestive of NETs (tests for inherited predisposition to tumors or for a clinical syndrome caused by abnormal hormone secretion)." ;
rdfs:subClassOf obo:MONDO_0002082 .
obo:ECTO_9002026 a rdfs:Class ;
rdfs:label "exposure to B vitamin" ;
rdfs:comment "An exposure to B vitamin." ;
rdfs:subClassOf obo:ECTO_0000371 , obo:ECTO_9000190 .
obo:ECTO_9000032 a rdfs:Class ;
rdfs:label "exposure to arsenic" ;
rdfs:comment "An exposure to arsenic molecular entity." ;
rdfs:subClassOf obo:ECTO_0000231 .
obo:HP_0002621 a rdfs:Class ;
rdfs:label "Atherosclerosis" ;
rdfs:comment "A condition characterized by patchy atheromas or atherosclerotic plaques which develop in the walls of medium-sized and large arteries and can lead to arterial stenosis with reduced or blocked blood flow." ;
rdfs:subClassOf obo:HP_0002634 .
obo:HP_0100659 a rdfs:Class ;
rdfs:label "Abnormal cerebral vascular morphology" ;
rdfs:comment "An anomaly of the cerebral blood vessels." ;
rdfs:subClassOf obo:HP_0012443 , obo:HP_0025015 .
obo:MONDO_0021074 a rdfs:Class ;
rdfs:label "precancerous condition" ;
rdfs:comment "A pathological process with signs indicating it may become cancerous. Representative examples include leukoplakia, dysplastic nevus, actinic keratosis, xeroderma pigmentosum, and intraepithelial neoplasia." ;
rdfs:subClassOf obo:MONDO_0045024 .
obo:ECTO_9000433 a rdfs:Class ;
rdfs:label "exposure to polycyclic arene" ;
rdfs:comment "An exposure to polycyclic arene." ;
rdfs:subClassOf obo:ECTO_9002148 .
obo:ECTO_9000215 a rdfs:Class ;
rdfs:label "exposure to lipopolysaccharide" ;
rdfs:comment "An exposure to lipopolysaccharide." ;
rdfs:subClassOf obo:ECTO_0000200 , obo:ECTO_0000371 .
obo:BFO_0000019 a rdfs:Class ;
rdfs:label "quality"@en ;
rdfs:subClassOf obo:BFO_0000020 .
obo:MONDO_0005328 a rdfs:Class ;
rdfs:label "eye disorder" ;
rdfs:comment "A non-neoplastic or neoplastic disorder that affects the eye. Representative examples include conjunctivitis, glaucoma, cataract, conjunctival squamous cell carcinoma, uveal melanoma, and retinoblastoma." ;
rdfs:subClassOf obo:MONDO_0002022 , obo:MONDO_0024458 .
obo:ECTO_0900332 a rdfs:Class ;
rdfs:label "exposure to nitrate via ingestion" ;
rdfs:comment "An exposure to nitrate via ingestion route." ;
rdfs:subClassOf obo:ECTO_0900042 , obo:ECTO_9000185 .
obo:MONDO_0006761 a rdfs:Class ;
rdfs:label "fibromuscular dysplasia" ;
rdfs:comment "A disorder characterized by fibrous thickening of the arterial wall resulting in narrowing of the arterial lumen. It most often affects the renal artery and less often the carotid artery and abdominal arteries. It can cause hypertension and aneurysm formation." ;
rdfs:subClassOf obo:MONDO_0000473 , obo:MONDO_0003847 .
obo:MONDO_0021251 a rdfs:Class ;
rdfs:label "endometrium neoplasm" ;
rdfs:comment "A neoplasm (disease) that involves the endometrium." ;
rdfs:subClassOf obo:MONDO_0000931 , obo:MONDO_0021353 .
obo:MONDO_0042981 a rdfs:Class ;
rdfs:label "aortic valve stenosis" ;
rdfs:comment "Aortic valve stenosis (AVS) is a condition characterized by narrowing of the heart's aortic valve opening. This narrowing prevents the valve from opening fully, which obstructs blood flow from the heart into the aorta, and onward to the rest of the body. AVS can range from mild to severe. Signs and symptoms typically develop when the narrowing of the opening is severe and may include chest pain (angina) or tightness; shortness of breath or fatigue (especially during exertion); feeling faint or fainting; heart palpitations; and heart murmur. Individuals with less severe congenital AVS (present at birth) may not develop symptoms until adulthood. Individuals with severe cases may faint without warning. AVS can have several causes including abnormal development before birth (such as having 1 or 2 valve leaflets instead of 3); calcium build-up on the valve in adulthood; and rheumatic fever." ;
rdfs:subClassOf obo:MONDO_0003803 , obo:MONDO_0021147 .
obo:MONDO_0021364 a rdfs:Class ;
rdfs:label "neoplasm of oropharynx" ;
rdfs:comment "A neoplasm (disease) that involves the oropharynx." ;
rdfs:subClassOf obo:MONDO_0004335 , obo:MONDO_0005586 , obo:MONDO_0020592 , obo:MONDO_0021246 .
obo:HP_0000539 a rdfs:Class ;
rdfs:label "Abnormality of refraction" ;
rdfs:comment "An abnormality in the process of focusing of light by the eye in order to produce a sharp image on the retina." ;
rdfs:subClassOf obo:HP_0012373 .
obo:MONDO_0002229 a rdfs:Class ;
rdfs:label "ovarian epithelial tumor" ;
rdfs:comment "A benign, borderline, or malignant tumor that originates from the surface epithelium of the ovary. It is composed of epithelial cells and stroma. Representative examples of benign tumors include serous cystadenoma, mucinous cystadenoma, and benign Brenner tumor. Representative examples of borderline tumors include serous surface papillary tumor, mucinous adenofibroma, and borderline Brenner tumor. Representative examples of malignant tumors include serous adenocarcinoma, mucinous adenocarcinoma, endometrioid adenocarcinoma, and malignant Brenner tumor." ;
rdfs:subClassOf obo:MONDO_0005626 , obo:MONDO_0021068 .
obo:MONDO_0002532 a rdfs:Class ;
rdfs:label "squamous cell neoplasm" ;
rdfs:comment "A neoplasm that is composed of squamous epithelial cells. Squamous cell carcinoma is a representative example." ;
rdfs:subClassOf obo:MONDO_0005626 .
obo:HP_0011446 a rdfs:Class ;
rdfs:label "Abnormality of mental function" ;
rdfs:comment "Cognitive, psychiatric, or memory anomaly." ;
rdfs:subClassOf obo:HP_0012638 .
obo:ECTO_0010001 a rdfs:Class ;
rdfs:label "exposure to qualitative environmental quality" ;
rdfs:comment "A exposure event involving the interaction of an exposure receptor to qualitative." ;
rdfs:subClassOf obo:ECTO_0010000 .
obo:MONDO_0002974 a rdfs:Class ;
rdfs:label "cervical cancer" ;
rdfs:comment "A primary or metastatic malignant neoplasm involving the cervix." ;
rdfs:subClassOf obo:MONDO_0002715 , obo:MONDO_0021230 .
obo:MONDO_0017343 a rdfs:Class ;
rdfs:label "Epstein-Barr virus-associated lymphoproliferative disorder" ;
rdfs:comment "A range of lymphoproliferative diseases characterized by uncontrolled proliferation of B cells, T cells, or NK cells infected with Epstein-Barr virus. Depending on host immunity and viral factors, viral persistence in host cells can induce lymphoproliferation with a diverse clinical spectrum ranging from simple reactive hyperplasia to aggressive lymphoma/leukemia with unique clinical and pathological presentations." ;
rdfs:subClassOf obo:MONDO_0017342 .
obo:ECTO_9002478 a rdfs:Class ;
rdfs:label "exposure to nicotinamide" ;
rdfs:comment "An exposure to nicotinamide." ;
rdfs:subClassOf obo:ECTO_0000163 , obo:ECTO_9000271 , obo:ECTO_9002845 .
obo:MONDO_0005515 a rdfs:Class ;
rdfs:label "oral cavity cancer" ;
rdfs:comment "A primary or metastatic malignant neoplasm involving the oral cavity. The majority are squamous cell carcinomas." ;
rdfs:subClassOf obo:MONDO_0002516 , obo:MONDO_0021245 .
obo:MONDO_0017276 a rdfs:Class ;
rdfs:label "frontotemporal dementia" ;
rdfs:comment "Frontotemporal dementia (FTD) comprises a group of neurodegenerative disorders, characterized by progressive changes in behavior, executive dysfunction and language impairment, as a result of degeneration of the medial prefrontal and frontoinsular cortices. Four clinical subtypes have been identified: semantic dementia, progressive non-fluent aphasia, behavioral variant FTD and right temporal lobar atrophy." ;
rdfs:subClassOf obo:MONDO_0015547 , obo:MONDO_0024237 .
obo:MONDO_0021085 a rdfs:Class ;
rdfs:label "gastric neoplasm" ;
rdfs:comment "A benign or malignant neoplasm involving the stomach." ;
rdfs:subClassOf obo:MONDO_0004298 , obo:MONDO_0021223 .
obo:MONDO_0005369 a rdfs:Class ;
rdfs:label "carcinoid tumor" ;
rdfs:comment "A slow growing neuroendocrine tumor, composed of uniform, round, or polygonal cells having monotonous, centrally located nuclei and small nucleoli, infrequent mitoses, and no necrosis. The tumor may show a variety of patterns, such as solid, trabecular, and acinar. Electron microscopy shows small secretory granules. Immunohistochemical studies reveal NSE, as well as chromogranin immunoreactivity. Malignant histology (cellular pleomorphism, hyperchromatic nuclei, prominent nucleoli, necrosis, and mitoses) can occasionally be seen. Such cases may have an aggressive clinical course. Gastrointestinal tract and lung are common sites of involvement." ;
rdfs:subClassOf obo:MONDO_0019496 .
obo:MONDO_0005835 a rdfs:Class ;
rdfs:label "Lynch syndrome" ;
rdfs:comment "An autosomal dominant hereditary neoplastic syndrome characterized by the development of colorectal carcinoma and a high risk of developing endometrial carcinoma, gastric carcinoma, ovarian carcinoma, renal pelvis carcinoma, and small intestinal carcinoma. Patients often develop colorectal carcinomas at an early age (mean, 45 years). In the majority of the cases the lesions arise from the proximal colon. At the molecular level, high-frequency microsatellite instability is present." ;
rdfs:subClassOf obo:MONDO_0000426 , obo:MONDO_0018630 .
obo:MONDO_0000745 a rdfs:Class ;
rdfs:label "cardiac arrest" ;
rdfs:comment "Cessation of breathing and/or cardiac function." ;
rdfs:subClassOf obo:MONDO_0007263 .
obo:MONDO_0000616 a rdfs:Class ;
rdfs:label "progesterone-receptor negative breast cancer" ;
rdfs:subClassOf obo:MONDO_0006116 .
obo:IAO_8000016 a rdfs:Class ;
rdfs:label "taxonomic bridge ontology module"@en ;
rdfs:subClassOf obo:IAO_8000004 .
obo:ECTO_0000487 a rdfs:Class ;
rdfs:label "exposure to chemical with chemical role" ;
rdfs:comment "An exposure to chemical role." ;
rdfs:subClassOf obo:ExO_0000002 .
obo:MONDO_0020213 a rdfs:Class ;
rdfs:label "stromal corneal dystrophy" ;
rdfs:comment "The stromal corneal dystrophies refer to a group of rare genetically determined corneal dystrophies (CDs) characterized by lesions affecting the corneal stroma, and variable effects on vision depending on the type of dystrophy." ;
rdfs:subClassOf obo:MONDO_0018102 .
obo:MONDO_0021243 a rdfs:Class ;
rdfs:label "parotid gland neoplasm" ;
rdfs:comment "A neoplasm (disease) that involves the parotid gland." ;
rdfs:subClassOf obo:MONDO_0005899 , obo:MONDO_0021368 .
obo:MONDO_0000594 a rdfs:Class ;
rdfs:label "pervasive developmental disorder" ;
rdfs:comment "A category of developmental disorders characterized by impaired communication and socialization skills. The impairments are incongruent with the individual's developmental level or mental age. These disorders can be associated with general medical or genetic conditions." ;
rdfs:subClassOf obo:MONDO_0005503 , obo:MONDO_0100038 .
obo:HP_0001945 a rdfs:Class ;
rdfs:label "Fever" ;
rdfs:comment "Body temperature elevated above the normal range." ;
rdfs:subClassOf obo:HP_0004370 .
obo:HP_0000545 a rdfs:Class ;
rdfs:label "Myopia" ;
rdfs:comment "An abnormality of refraction characterized by the ability to see objects nearby clearly, while objects in the distance appear blurry." ;
rdfs:subClassOf obo:HP_0000539 .
obo:MONDO_0700038 a rdfs:Class ;
rdfs:label "TDP-43 proteinopathy" ;
rdfs:comment "Disease characterized by the presence of abnormally phosphorylated, ubiquitinated, and cleaved DNA-binding protein TDP-43 in affected brain and spinal cord. Inclusions of the pathologic protein in neurons and glia, without the presence of AMYLOID, is the major feature of these conditions, thus making these proteinopathies distinct from most other neurogenerative disorders in which protein misfolding leads to brain amyloidosis. Both frontotemporal lobar degeneration and AMYOTROPHIC LATERAL SCLEROSIS exhibit this common method of pathogenesis and thus they may represent two extremes of a continuous clinicopathological spectrum of one disease." ;
rdfs:subClassOf obo:MONDO_0021179 .
obo:MONDO_0005010 a rdfs:Class ;
rdfs:label "coronary artery disorder" ;
rdfs:comment "Narrowing of the coronary arteries due to fatty deposits inside the arterial walls. The diagnostic criteria may include documented history of any of the following: documented coronary artery stenosis greater than or equal to 50% (by cardiac catheterization or other modality of direct imaging of the coronary arteries); previous coronary artery bypass surgery (CABG); previous percutaneous coronary intervention (PCI); previous myocardial infarction. (ACC)" ;
rdfs:subClassOf obo:MONDO_0000473 , obo:MONDO_0005267 .
obo:MONDO_0004972 a rdfs:Class ;
rdfs:label "adenoma" ;
rdfs:comment "A neoplasm arising from the epithelium. It may be encapsulated or non-encapsulated but non-invasive. The neoplastic epithelial cells may or may not display cellular atypia or dysplasia. In the gastrointestinal tract, when dysplasia becomes severe it is sometimes called carcinoma in situ. Representative examples are pituitary gland adenoma, follicular adenoma of the thyroid gland, and adenomas (or adenomatous polyps) of the gastrointestinal tract." ;
rdfs:subClassOf obo:MONDO_0005626 .
obo:HP_0000252 a rdfs:Class ;
rdfs:label "Microcephaly" ;
rdfs:comment "Head circumference below 2 standard deviations below the mean for age and gender." ;
rdfs:subClassOf obo:HP_0007364 , obo:HP_0040195 .
obo:MONDO_0005395 a rdfs:Class ;
rdfs:label "movement disorder" ;
rdfs:comment "Neurological conditions resulting in abnormal voluntary or involuntary movement, which may impact the speed, fluency, quality and ease of movement." ;
rdfs:subClassOf obo:MONDO_0005071 .
obo:MONDO_0019268 a rdfs:Class ;
rdfs:label "epidermal disease" ;
rdfs:comment "A skin disease that involves the epidermis." ;
rdfs:subClassOf obo:MONDO_0005093 .
obo:MONDO_0020120 a rdfs:Class ;
rdfs:label "skeletal muscle disorder" ;
rdfs:comment "A disease involving the skeletal muscle tissue." ;
rdfs:subClassOf obo:MONDO_0003939 .
obo:MONDO_0019060 a rdfs:Class ;
rdfs:label "bone neoplasm" ;
rdfs:comment "A benign, intermediate, or malignant neoplasm involving the bone or articular cartilage." ;
rdfs:subClassOf obo:MONDO_0005381 , obo:MONDO_0021581 .
obo:MONDO_0015185 a rdfs:Class ;
rdfs:label "intestinal polyposis syndrome" ;
rdfs:comment "A syndrome associated with the development of multiple polyps throughout the intestine. It includes familial adenomatous polyposis , hamartomatous polyposis syndromes, and other rare polyposis syndromes." ;
rdfs:subClassOf obo:MONDO_0015356 .
obo:MONDO_0700220 a rdfs:Class ;
rdfs:label "disease related to transplantation" ;
rdfs:comment "Disease that occurs as a consequence of immunosuppression in a recipient of a solid organ or bone marrow transplant, or as a consequence of the transplantation." ;
rdfs:subClassOf obo:MONDO_7770010 .
obo:MONDO_0015129 a rdfs:Class ;
rdfs:label "chronic primary adrenal insufficiency" ;
rdfs:comment "A chronic disorder of the adrenal cortex resulting in the inadequate production of glucocorticoid and mineralocorticoid hormones." ;
rdfs:subClassOf obo:MONDO_0015128 .
obo:ECTO_7000034 a rdfs:Class ;
rdfs:label "exposure to wood" ;
rdfs:comment "A exposure event involving the interaction of an exposure receptor to wood." ;
rdfs:subClassOf obo:ECTO_7000069 .
obo:NCIT_C16632 a rdfs:Class ;
rdfs:label "Geographic Area" ;
rdfs:subClassOf obo:NCIT_C20181 .
obo:MONDO_0002488 a rdfs:Class ;
rdfs:label "intraductal breast neoplasm" ;
rdfs:comment "A benign or malignant epithelial neoplasm that arises anywhere in the ductal system of the breast. This category includes intraductal papilloma, intraductal papillary carcinoma, ductal hyperplasia with or without atypia, and ductal carcinoma in situ." ;
rdfs:subClassOf obo:MONDO_0021100 .
obo:MONDO_0024257 a rdfs:Class ;
rdfs:label "hereditary motor neuron disease" ;
rdfs:comment "An instance of motor neuron disease that is caused by an inherited modification of the individual's genome." ;
rdfs:subClassOf obo:MONDO_0020128 , obo:MONDO_0024237 , obo:MONDO_0100546 .
obo:MONDO_0021113 a rdfs:Class ;
rdfs:label "respiratory failure" ;
rdfs:comment "The significant impairment of gas exchange within the lungs resulting in hypoxia, hypercarbia, or both, to the extent that organ tissue perfusion is severely compromised. Causes include chronic obstructive pulmonary disease, asthma, emphysema, acute respiratory distress syndrome, pneumonia, pulmonary edema, pneumothorax, and congestive heart failure. Treatment requires intubation and mechanical ventilation until the time the lungs recover sufficient function." ;
rdfs:subClassOf obo:MONDO_0005275 .
obo:MONDO_0006058 a rdfs:Class ;
rdfs:label "Wilms tumor" ;
rdfs:comment "An embryonal neoplasm characterized by the presence of epithelial, mesenchymal, and blastema components. The vast majority of cases arise from the kidney. A small number of cases with morphologic features resembling Wilms tumor of the kidney have been reported arising from the ovary and the cervix." ;
rdfs:subClassOf obo:MONDO_0005564 , obo:MONDO_0005853 .
obo:MONDO_0005707 a rdfs:Class ;
rdfs:label "coccidiosis" ;
rdfs:comment "A parasitic infection caused by Coccidia. It affects livestock, birds and humans. In humans the parasite infests the intestinal tract and may cause watery diarrhea, abdominal pain, fever, nausea and vomiting." ;
rdfs:subClassOf obo:MONDO_0002428 .
obo:MONDO_0010030 a rdfs:Class ;
rdfs:label "Sjogren syndrome" ;
rdfs:comment "An autoimmune disorder in which immune cells attack and destroy the glands that produce tears and saliva. Sjögren syndrome is also associated with rheumatic disorders such as rheumatoid arthritis or systemic lupus erythematosus. The hallmark symptoms of Sjögren syndrome are dry mouth and dry eyes. In addition, Sjogren syndrome may cause skin, nose, and vaginal dryness. It also may affect other organs of the body including the kidneys, blood vessels, lungs, liver, pancreas, and brain" ;
rdfs:subClassOf obo:MONDO_0000586 , obo:MONDO_0001142 , obo:MONDO_0002254 , obo:MONDO_0024625 .
obo:MONDO_0002220 a rdfs:Class ;
rdfs:label "tooth hard tissue disease" ;
rdfs:subClassOf obo:MONDO_0006999 .
obo:MONDO_0024337 a rdfs:Class ;
rdfs:label "urothelial neoplasm" ;
rdfs:comment "A neoplasm involving a urothelium." ;
rdfs:subClassOf obo:MONDO_0021066 , obo:MONDO_0037254 .
obo:HP_0000234 a rdfs:Class ;
rdfs:label "Abnormality of the head" ;
rdfs:comment "An abnormality of the head." ;
rdfs:subClassOf obo:HP_0000152 .
obo:MONDO_0006858 a rdfs:Class ;
rdfs:label "mouth disorder" ;
rdfs:comment "A disease involving the mouth." ;
rdfs:subClassOf obo:MONDO_7770006 .
obo:ECTO_3000289 a rdfs:Class ;
rdfs:label "exposure to Human immunodeficiency virus" ;
rdfs:comment "A history of exposure to Human immunodeficiency virus." ;
rdfs:subClassOf obo:ECTO_3000001 .
obo:MONDO_0007263 a rdfs:Class ;
rdfs:label "cardiac rhythm disease" ;
rdfs:comment "Any variation from the normal rate or rhythm (which may include the origin of the impulse and/or its subsequent propagation) in the heart." ;
rdfs:subClassOf obo:MONDO_0005267 .
obo:MONDO_0004949 a rdfs:Class ;
rdfs:label "neoplasm of mature B-cells" ;
rdfs:comment "A neoplasm of follicle center B cells which has at least a partial follicular pattern. Follicular lymphomas comprise about 35% of adult non-Hodgkin lymphomas in the U.S. and 22% worldwide. Most patients have widespread disease at diagnosis. Morphologically, follicular lymphomas are classified as Grade 1, Grade 2, and Grade 3, depending on the percentage of the large lymphocytes present. The vast majority of cases (70-95%) express the BCL-2 rearrangement [t(14;18)]. Histological grade correlates with prognosis. Grades 1 and 2 follicular lymphomas are indolent and grade 3 is more aggressive (adapted from WHO, 2001)." ;
rdfs:subClassOf obo:MONDO_0004095 .
obo:MONDO_0005872 a rdfs:Class ;
rdfs:label "nervous system cancer" ;
rdfs:comment "A primary or metastatic malignant neoplasm involving the nervous system." ;
rdfs:subClassOf obo:MONDO_0004992 , obo:MONDO_0021248 .
obo:HP_0002664 a rdfs:Class ;
rdfs:label "Neoplasm" ;
rdfs:comment "An organ or organ-system abnormality that consists of uncontrolled autonomous cell-proliferation which can occur in any part of the body as a benign or malignant neoplasm (tumor)." ;
rdfs:subClassOf obo:HP_0000118 .
obo:MONDO_0018364 a rdfs:Class ;
rdfs:label "malignant epithelial tumor of ovary" ;
rdfs:comment "An invasive malignant tumor that originates from the surface epithelium of the ovary. It is composed of malignant epithelial cells and stroma. Representative examples include serous adenocarcinoma, mucinous adenocarcinoma, endometrioid adenocarcinoma, clear cell adenocarcinoma, and malignant Brenner tumor." ;
rdfs:subClassOf obo:MONDO_0002229 , obo:MONDO_0004993 , obo:MONDO_0008170 .
obo:MONDO_0005718 a rdfs:Class ;
rdfs:label "Coronaviridae infectious disease" ;
rdfs:comment "Virus diseases caused by coronaviridae." ;
rdfs:subClassOf obo:MONDO_0005876 .
obo:MONDO_0002082 a rdfs:Class ;
rdfs:label "endocrine gland neoplasm" ;
rdfs:comment "A benign or malignant neoplasm arising from the epithelial cells of an endocrine organ. Representative examples include pituitary gland adenoma, pituitary gland carcinoma, thyroid gland carcinoma, carcinoid tumor, and neuroendocrine carcinoma." ;
rdfs:subClassOf obo:MONDO_0005070 , obo:MONDO_0005151 .
obo:MONDO_1060134 a rdfs:Class ;
rdfs:label "atherosclerotic cardiovascular disease" ;
rdfs:comment "Any cardiovascular disease resulting from atherosclerosis." ;
rdfs:subClassOf obo:MONDO_0005311 .
obo:MONDO_0044996 a rdfs:Class ;
rdfs:label "cerebral cortex disorder" ;
rdfs:comment "A disease or disorder that involves the cerebral cortex." ;
rdfs:subClassOf obo:MONDO_0005560 .
obo:MONDO_0005213 a rdfs:Class ;
rdfs:label "uterine carcinoma" ;
rdfs:comment "A carcinoma involving a uterus." ;
rdfs:subClassOf obo:MONDO_0002715 , obo:MONDO_0004993 .
obo:ECTO_0600002 a rdfs:Class ;
rdfs:label "exposure to child care environment" ;
rdfs:comment "A exposure event involving the interaction of an exposure receptor to child care environment." ;
rdfs:subClassOf obo:ECTO_0600000 .
obo:ECTO_0000481 a rdfs:Class ;
rdfs:label "exposure to transition element" ;
rdfs:comment "An exposure to transition element molecular entity." ;
rdfs:subClassOf obo:ECTO_0000231 .
obo:HP_0100326 a rdfs:Class ;
rdfs:label "Immunologic hypersensitivity" ;
rdfs:comment "Immunological states where the immune system produces harmful responses upon reexposure to sensitizing antigens." ;
rdfs:subClassOf obo:HP_0010978 .
obo:HP_0011013 a rdfs:Class ;
rdfs:label "Abnormal circulating carbohydrate concentration" ;
rdfs:comment "A deviation from the normal concentration of a carbohydrate in the blood circulation." ;
rdfs:subClassOf obo:HP_0430071 .
obo:ECTO_9002160 a rdfs:Class ;
rdfs:label "exposure to perfluoroalkyl substance" ;
rdfs:comment "An exposure to perfluoroalkyl substance." ;
rdfs:subClassOf obo:ECTO_9001620 .
obo:IAO_8000012 a rdfs:Class ;
rdfs:label "species subset ontology module"@en ;
rdfs:comment "A subset ontology that is crafted to either include or exclude a taxonomic grouping of species."@en ;
rdfs:seeAlso ;
rdfs:subClassOf obo:IAO_8000006 .
obo:MONDO_7770005 a rdfs:Class ;
rdfs:label "cystic fibrosis-related liver disease" ;
rdfs:comment "A liver disorder that arises as a consequence of cystic fibrosis. Cystic fibrosis-related liver disease encompasses a spectrum of hepatobiliary abnormalities caused by CFTR dysfunction in cholangiocytes, including focal biliary cirrhosis, multilobular biliary cirrhosis, hepatic steatosis, and cholangiopathy. It is a significant cause of non-pulmonary morbidity and mortality in CF, affecting approximately 5-10% of CF patients." ;
rdfs:subClassOf obo:MONDO_0005154 .
obo:MONDO_0012727 a rdfs:Class ;
rdfs:label "Kawasaki disease" ;
rdfs:comment "A rare inflammatory disease characterized by an acute febrile, systemic, self-limiting, medium-vessel vasculitis primarily affecting children. It often causes acute coronary arteritis which is associated with coronary arterial aneurysms (CAA) that may be life threatening when untreated." ;
rdfs:subClassOf obo:MONDO_0002052 , obo:MONDO_0018882 .
obo:MONDO_0002156 a rdfs:Class ;
rdfs:label "fallopian tube disorder" ;
rdfs:comment "A disease involving the fallopian tube." ;
rdfs:subClassOf obo:MONDO_0002263 .
obo:IAO_8000001 a rdfs:Class ;
rdfs:label "base ontology module"@en ;
rdfs:comment "An ontology module that comprises only of asserted axioms local to the ontology, excludes import directives, and excludes axioms or declarations from external ontologies."@en ;
rdfs:seeAlso ;
rdfs:subClassOf obo:IAO_8000000 .
obo:MONDO_0005108 a rdfs:Class ;
rdfs:label "viral infectious disease" ;
rdfs:comment "Any disease caused by a virus." ;
rdfs:subClassOf obo:MONDO_0005550 .
obo:MONDO_0005384 a rdfs:Class ;
rdfs:label "focal epilepsy" ;
rdfs:comment "A seizure caused by a localized disorder." ;
rdfs:subClassOf obo:MONDO_0005027 .
obo:MONDO_0005578 a rdfs:Class ;
rdfs:label "arthritic joint disease" ;
rdfs:comment "An inflammatory process affecting a joint. Causes include infection, autoimmune processes, degenerative processes, and trauma. Signs and symptoms may include swelling around the affected joint and pain." ;
rdfs:subClassOf obo:MONDO_0002614 , obo:MONDO_0006816 , obo:MONDO_0021166 .
obo:MONDO_0024664 a rdfs:Class ;
rdfs:label "hypertension, pregnancy-induced" ;
rdfs:comment "A hypertensive disorder that develops during pregnancy." ;
rdfs:subClassOf obo:MONDO_0005044 , obo:MONDO_0024575 .
obo:HP_0032325 a rdfs:Class ;
rdfs:label "Lacunar stroke" ;
rdfs:comment "A stroke related to a small infarct (2-20 mm in diameter) in the deep cerebral white matter, basal ganglia, or pons, that is presumed to result from the occlusion of a single small perforating artery supplying the subcortical areas of the brain." ;
rdfs:subClassOf obo:HP_0002140 .
obo:MONDO_0021148 a rdfs:Class ;
rdfs:label "female reproductive system neoplasm" ;
rdfs:comment "A benign, precancerous, or malignant neoplasm that affects the female reproductive system. Representative examples include uterine corpus leiomyoma, endocervical polyp, ovarian carcinoma, cervical carcinoma, and endometrial carcinoma." ;
rdfs:subClassOf obo:MONDO_0002263 , obo:MONDO_0006054 .
obo:MONDO_0002928 a rdfs:Class ;
rdfs:label "carcinosarcoma" ;
rdfs:comment "A malignant tumor composed of a mixture of carcinomatous and sarcomatous elements." ;
rdfs:subClassOf obo:MONDO_0005853 .
obo:HP_0100716 a rdfs:Class ;
rdfs:label "Self-injurious behavior" ;
rdfs:comment "Self-aggression." ;
rdfs:subClassOf obo:HP_5200241 .
obo:MONDO_0006949 a rdfs:Class ;
rdfs:label "retinal drusen" ;
rdfs:comment "Colloid or hyaline bodies lying beneath the retinal pigment epithelium. They may occur either secondary to changes in the choroid that affect the pigment epithelium or as an autosomal dominant disorder of the retinal pigment epithelium." ;
rdfs:subClassOf obo:MONDO_0002175 .
obo:MONDO_0003812 a rdfs:Class ;
rdfs:label "ovarian endometrial cancer" ;
rdfs:comment "A benign, borderline, or malignant epithelial tumor of the ovary characterized by the presence of glands and/or cysts lined by neoplastic cells that resemble endometrial cells." ;
rdfs:subClassOf obo:MONDO_0002480 , obo:MONDO_0018364 .
obo:HP_0032101 a rdfs:Class ;
rdfs:label "Unusual infection" ;
rdfs:comment "Increased susceptibility to infection, as manifested by recurrent infection, severe or invasive infection, infection occurring in an unusual anatomical location, or infection with opportunistic organisms, that is unusual for a healthy individual of the same age." ;
rdfs:subClassOf obo:HP_0010978 .
obo:BFO_0000020 a rdfs:Class ;
rdfs:label "specifically dependent continuant"@en ;
rdfs:comment "b is a specifically dependent continuant = Def. b is a continuant & there is some independent continuant c which is not a spatial region and which is such that b s-depends_on c at every time t during the course of b’s existence. (axiom label in BFO2 Reference: [050-003])"@en ;
rdfs:subClassOf obo:BFO_0000002 .
obo:MONDO_0005401 a rdfs:Class ;
rdfs:label "colonic neoplasm" ;
rdfs:comment "A benign or malignant neoplasm that affects the colon. Representative examples of benign neoplasms include lipoma and leiomyoma. Representative examples of malignant neoplasms include carcinoma, lymphoma, and sarcoma. Colonic adenomas always exhibit epithelial dysplasia and are considered premalignant neoplasms." ;
rdfs:subClassOf obo:MONDO_0003409 , obo:MONDO_0005335 .
obo:MONDO_0024644 a rdfs:Class ;
rdfs:label "myocardial ischemia" ;
rdfs:comment "A disorder of cardiac function caused by insufficient blood flow to the muscle tissue of the heart. The decreased blood flow may be due to narrowing of the coronary arteries (coronary artery disease), to obstruction by a thrombus (coronary thrombosis), or less commonly, to diffuse narrowing of arterioles and other small vessels within the heart. Severe interruption of the blood supply to the myocardial tissue may result in necrosis of cardiac muscle (myocardial infarction)." ;
rdfs:subClassOf obo:MONDO_0005053 , obo:MONDO_0024643 .
obo:MONDO_0005623 a rdfs:Class ;
rdfs:label "autoimmune thyroid disease" ;
rdfs:comment "Inflammatory disease of the thyroid gland due to autoimmune responses leading to lymphocytic infiltration of the gland. It is characterized by the presence of circulating thyroid antigen-specific T-cells and thyroid autoantibodies. The clinical signs can range from hypothyroidism to thyrotoxicosis depending on the type of autoimmune thyroiditis." ;
rdfs:subClassOf obo:MONDO_0000569 , obo:MONDO_0004126 .
obo:MONDO_0004938 a rdfs:Class ;
rdfs:label "substance dependence" ;
rdfs:comment "The psychological or physiological need to take a substance in order to experience its effects or to avoid the effects of its absence." ;
rdfs:subClassOf obo:MONDO_0002494 .
obo:ECTO_2000118 a rdfs:Class ;
rdfs:label "exposure to fasting intervention" ;
rdfs:comment "An exposure to fasting intervention." ;
rdfs:subClassOf obo:ECTO_2000000 .
obo:ECTO_0100003 a rdfs:Class ;
rdfs:label "exposure to cigarette smoking" ;
rdfs:comment "An exposure event involving nicotine cigarette smoking behavior" ;
rdfs:subClassOf obo:ECTO_0100002 .
obo:ECTO_0050001 a rdfs:Class ;
rdfs:label "exposure to mediterranean diet" ;
rdfs:comment "An exposure event involving mediterranean diet" ;
rdfs:subClassOf obo:ECTO_0000015 .
obo:MONDO_0021187 a rdfs:Class ;
rdfs:label "hyperlipidemia" ;
rdfs:subClassOf obo:MONDO_0005066 .
obo:MONDO_0002116 a rdfs:Class ;
rdfs:label "malignant exocrine pancreas neoplasm" ;
rdfs:comment "A malignant neoplasm that arises from the epithelial cells of the exocrine pancreatic tissue." ;
rdfs:subClassOf obo:MONDO_0009831 , obo:MONDO_0021076 .
obo:MONDO_0002022 a rdfs:Class ;
rdfs:label "disorder of orbital region" ;
rdfs:comment "A disease that involves the orbital region." ;
rdfs:subClassOf obo:MONDO_7770006 .
obo:MONDO_0016093 a rdfs:Class ;
rdfs:label "borderline epithelial tumor of ovary" ;
rdfs:comment "A low grade epithelial tumor arising from the ovary. It is characterized by an atypical proliferation of epithelial cells. There is no evidence of stromal invasion." ;
rdfs:subClassOf obo:MONDO_0002229 .
obo:MONDO_0002149 a rdfs:Class ;
rdfs:label "reproductive system cancer" ;
rdfs:comment "A malignant neoplasm involving the reproductive organ" ;
rdfs:subClassOf obo:MONDO_0004992 , obo:MONDO_0006054 .
obo:MONDO_0100096 a rdfs:Class ;
rdfs:label "COVID-19" ;
rdfs:comment "A disease caused by infection with severe acute respiratory syndrome coronavirus 2." ;
rdfs:subClassOf obo:MONDO_0020753 .
obo:MONDO_0004335 a rdfs:Class ;
rdfs:label "digestive system disorder" ;
rdfs:comment "A disease or disorder that involves the digestive system." ;
rdfs:subClassOf obo:MONDO_7770006 .
obo:MONDO_0100313 a rdfs:Class ;
rdfs:label "focal segmental glomerulosclerosis" ;
rdfs:comment "A renal disorder characterized by sclerotic lesions in the glomeruli. Causes include drugs, viruses, and malignancies (lymphomas), or it may be idiopathic. It presents with asymptomatic proteinuria or nephritic syndrome and it may lead to renal failure." ;
rdfs:subClassOf obo:MONDO_0000490 , obo:MONDO_0700328 .
obo:ECTO_9000203 a rdfs:Class ;
rdfs:label "exposure to amine" ;
rdfs:comment "An exposure to amine." ;
rdfs:subClassOf obo:ECTO_9000190 .
obo:MONDO_0001941 a rdfs:Class ;
rdfs:label "blindness (disorder)" ;
rdfs:comment "The lack of vision. It is caused by neurological or physiological factors." ;
rdfs:subClassOf obo:MONDO_0021084 .
obo:ECTO_0300003 a rdfs:Class ;
rdfs:label "exposure to cigarette smoking via maternal" ;
rdfs:comment "An exposure event involving nicotine cigarette smoking behavior via maternal" ;
rdfs:subClassOf obo:ECTO_0100003 , obo:ECTO_0300002 .
obo:MONDO_0016685 a rdfs:Class ;
rdfs:label "low-grade astrocytoma" ;
rdfs:subClassOf obo:MONDO_0019781 , obo:MONDO_0021638 .
obo:MONDO_0021071 a rdfs:Class ;
rdfs:label "laryngeal neoplasm" ;
rdfs:comment "A benign or malignant neoplasm involving the larynx." ;
rdfs:subClassOf obo:MONDO_0004382 , obo:MONDO_0020641 .
obo:MONDO_0006325 a rdfs:Class ;
rdfs:label "ocular melanoma" ;
rdfs:comment "A melanoma that arises from the structures of the eye or ocular adnexa." ;
rdfs:subClassOf obo:MONDO_0002236 , obo:MONDO_0005105 .
obo:MONDO_0005036 a rdfs:Class ;
rdfs:label "gastric adenocarcinoma" ;
rdfs:comment "A carcinoma that arises from glandular epithelial cells of the stomach" ;
rdfs:subClassOf obo:MONDO_0004950 , obo:MONDO_0004970 .
a rdfs:Class ;
rdfs:label "cohort"@en ;
rdfs:comment "A group of individuals grouped together based on a shared characteristic or property of interest." .
a rdf:Property ;
rdfs:label "isSubCohortOf"@en ;
rdfs:comment "A relation between a cohort and the cohort its participants are drawn from, of which it is a sub-study, a sub-sample or a component trial."@en ;
rdfs:domain ;
rdfs:range .
a rdf:Property ;
rdfs:label "hasSubCohort"@en ;
rdfs:comment "A relation between a cohort and a cohort whose participants are drawn from it: a sub-study, a sub-sample or a component trial. The inverse of isSubCohortOf."@en ;
rdfs:domain ;
rdfs:range .
obo:MONDO_0006025 a rdfs:Class ;
rdfs:label "autosomal recessive disease" ;
rdfs:comment "Autosomal recessive form of disease." ;
rdfs:subClassOf obo:MONDO_0000429 .
obo:MONDO_0700124 a rdfs:Class ;
rdfs:label "chromosome 21 disorder" ;
rdfs:comment "Chromosomal disorder in which chromosome 21 is affected." ;
rdfs:subClassOf obo:MONDO_0020049 .
obo:MONDO_0005021 a rdfs:Class ;
rdfs:label "dilated cardiomyopathy" ;
rdfs:comment "Cardiomyopathy which is characterized by dilation and contractile dysfunction of the left and right ventricles. It may be idiopathic, or it may result from a myocardial infarction, myocardial infection, or alcohol abuse. It is a cause of congestive heart failure." ;
rdfs:subClassOf obo:MONDO_0000591 .
obo:MONDO_0003757 a rdfs:Class ;
rdfs:label "paraplegia" ;
rdfs:comment "Complete paralysis of the lower half of the body including both legs, often caused by damage to the spinal cord." ;
rdfs:subClassOf obo:MONDO_0006496 .
obo:ECTO_0800003 a rdfs:Class ;
rdfs:label "exposure to famine via maternal" ;
rdfs:comment "A exposure event involving the interaction of an exposure receptor to famine happening in maternal of the receptor." ;
rdfs:subClassOf obo:ECTO_0800001 .
obo:MONDO_0002514 a rdfs:Class ;
rdfs:label "hepatobiliary neoplasm" ;
rdfs:comment "A benign or malignant neoplasm that affects the liver parenchyma, bile ducts, and gallbladder. Representative examples of benign neoplasms include hepatocellular adenoma, bile duct adenoma, and gallbladder lipoma. Representative examples of malignant neoplasms include hepatocellular carcinoma, intrahepatic and extrahepatic cholangiocarcinoma, and gallbladder carcinoma." ;
rdfs:subClassOf obo:MONDO_0002515 , obo:MONDO_0021223 .
obo:MONDO_0002052 a rdfs:Class ;
rdfs:label "lymphadenitis" ;
rdfs:comment "Acute or chronic inflammation of one or more lymph nodes. It is usually caused by an infectious process." ;
rdfs:subClassOf obo:MONDO_0004928 , obo:MONDO_0021166 .
obo:MONDO_0000569 a rdfs:Class ;
rdfs:label "autoimmune disorder of endocrine system" ;
rdfs:comment "A hypersensitivity reaction type II disease that involves the endocrine system." ;
rdfs:subClassOf obo:MONDO_0005151 , obo:MONDO_0007179 .
obo:MONDO_0024352 a rdfs:Class ;
rdfs:label "viral respiratory tract infection" ;
rdfs:comment "A respiratory tract infection caused by a virus. Viruses represent the most common causes of upper and lower respiratory tract infections and include rhinoviruses, influenza viruses, parainfluenza viruses, and respiratory syncytial virus." ;
rdfs:subClassOf obo:MONDO_0005108 , obo:MONDO_0024355 .
obo:MONDO_0022742 a rdfs:Class ;
rdfs:label "occupational asthma" ;
rdfs:comment "Asthma attacks caused, triggered, or exacerbated by OCCUPATIONAL EXPOSURE." ;
rdfs:subClassOf obo:MONDO_0004979 , obo:MONDO_0022736 .
obo:MONDO_0005155 a rdfs:Class ;
rdfs:label "cirrhosis of liver" ;
rdfs:comment "A disorder characterized by replacement of the liver parenchyma with fibrous tissue and regenerative nodules. It is usually caused by alcoholism, hepatitis B, and hepatitis C. Complications include the development of ascites, esophageal varices, bleeding, and hepatic encephalopathy." ;
rdfs:subClassOf obo:MONDO_0005154 .
obo:MONDO_0004781 a rdfs:Class ;
rdfs:label "acute myocardial infarction" ;
rdfs:comment "Necrosis of the myocardium, as a result of interruption of the blood supply to the area. It is characterized by a severe and rapid onset of symptoms that may include chest pain, often radiating to the left arm and left side of the neck, dyspnea, sweating, and palpitations." ;
rdfs:subClassOf obo:MONDO_0005068 , obo:MONDO_0020683 .
obo:MONDO_0005068 a rdfs:Class ;
rdfs:label "myocardial infarction" ;
rdfs:comment "Gross necrosis of the myocardium, as a result of interruption of the blood supply to the area, as in coronary thrombosis." ;
rdfs:subClassOf obo:MONDO_0024643 .
obo:MONDO_0002182 a rdfs:Class ;
rdfs:label "communication disorder" ;
rdfs:comment "A disorder characterized by an individual's inability to comprehend or share ideas or feelings because of an impairment in language, speech, or hearing." ;
rdfs:subClassOf obo:MONDO_0000592 .
obo:MONDO_0002752 a rdfs:Class ;
rdfs:label "ovarian adenocarcinoma" ;
rdfs:comment "An adenocarcinoma that arises from the ovary. It is the most common type of ovarian carcinoma. It includes the serous adenocarcinoma, mucinous adenocarcinoma, clear cell adenocarcinoma, and endometrioid adenocarcinoma." ;
rdfs:subClassOf obo:MONDO_0004970 , obo:MONDO_0005140 .
obo:MONDO_0005170 a rdfs:Class ;
rdfs:label "myeloid neoplasm" ;
rdfs:comment "Proliferation of myeloid cells originating from a primitive stem cell." ;
rdfs:subClassOf obo:MONDO_0044881 .
obo:ECTO_7000001 a rdfs:Class ;
rdfs:label "exposure to dust" ;
rdfs:comment "A exposure event involving the interaction of an exposure receptor to dust." ;
rdfs:subClassOf obo:ECTO_7000068 .
obo:ECTO_0100006 a rdfs:Class ;
rdfs:label "exposure to morphiane alkaloid" ;
rdfs:comment "An exposure event involving morphinane alkaloid consumption of an addictive substance" ;
rdfs:subClassOf obo:ExO_0000002 .
obo:MONDO_0000605 a rdfs:Class ;
rdfs:label "hypersensitivity reaction disease" ;
rdfs:comment "An immune system disease that has basis in dysregulation of the hypersensitivity reaction, an inflammatory response to an exogenous environmental antigen or an endogenous antigen initiated by the adaptive immune system." ;
rdfs:subClassOf obo:MONDO_0005046 .
obo:MONDO_0002525 a rdfs:Class ;
rdfs:label "inherited lipid metabolism disorder" ;
rdfs:comment "An inherited metabolic disorder caused by an enzyme deficiency, resulting in an inability to oxidize fatty acids for energy production." ;
rdfs:subClassOf obo:MONDO_0019052 .
obo:HP_0003418 a rdfs:Class ;
rdfs:label "Back pain" ;
rdfs:comment "An unpleasant sensation characterized by physical discomfort (such as pricking, throbbing, or aching) localized to the back." ;
rdfs:subClassOf obo:HP_0000925 , obo:HP_0012531 .
obo:HP_0200134 a rdfs:Class ;
rdfs:label "Epileptic encephalopathy" ;
rdfs:comment "A condition in which epileptiform abnormalities are believed to contribute to the progressive disturbance in cerebral function. Epileptic encephalaopathy is characterized by (1) electrographic EEG paroxysmal activity that is often aggressive, (2) seizures that are usually multiform and intractable, (3) cognitive, behavioral and neurological deficits that may be relentless, and (4) sometimes early death." ;
rdfs:subClassOf obo:HP_0001298 .
obo:MONDO_0001134 a rdfs:Class ;
rdfs:label "essential hypertension" ;
rdfs:comment "Hypertension that presents without an identifiable cause." ;
rdfs:subClassOf obo:MONDO_0005044 .
obo:ECTO_0000543 a rdfs:Class ;
rdfs:label "exposure to molecular messenger" ;
rdfs:comment "An exposure to molecular messenger." ;
rdfs:subClassOf obo:ECTO_0000485 .
obo:MONDO_0024634 a rdfs:Class ;
rdfs:label "large intestine disorder" ;
rdfs:comment "A disease that involves the large intestine." ;
rdfs:subClassOf obo:MONDO_0005020 .
obo:HP_0001647 a rdfs:Class ;
rdfs:label "Bicuspid aortic valve" ;
rdfs:comment "The presence of an aortic valve with two instead of the normal three cusps (flaps). Bicuspid aortic valvue is a malformation of a commissure (small space between the attachment of each cusp to the aortic wall) and the adjacent parts of the two corresponding cusps forming a raphe (the fused area of the two underdeveloped cusps turning into a malformed commissure between both cusps; the raphe is a fibrous ridge that extends from the commissure to the free edge of the two underdeveloped, conjoint cusps)." ;
rdfs:subClassOf obo:HP_0031567 .
obo:MONDO_0015757 a rdfs:Class ;
rdfs:label "lymphoid hemopathy" ;
rdfs:subClassOf obo:MONDO_0002334 .
obo:MONDO_0024474 a rdfs:Class ;
rdfs:label "intraepithelial neoplasia" ;
rdfs:comment "A precancerous neoplastic process that affects the squamous, glandular, or transitional cell epithelium without evidence of invasion. According to the degree of nuclear atypia, number of mitotic figures, and presence of architectural distortion, it is classified as low grade (mild dysplasia) or high grade (moderate or severe dysplasia)." ;
rdfs:subClassOf obo:MONDO_0005626 , obo:MONDO_0021074 .
obo:MONDO_0016743 a rdfs:Class ;
rdfs:label "tumor of meninges" ;
rdfs:comment "A benign or malignant neoplasm that affects the meninges. The majority of the neoplasms arise from meningothelial cells and are called meningiomas. Non-meningothelial cell neoplasms include mesenchymal, non-meningothelial tumors, hemangiopericytomas, and melanocytic lesions." ;
rdfs:subClassOf obo:MONDO_0006130 .
obo:ECTO_9000553 a rdfs:Class ;
rdfs:label "exposure to chlordecone" ;
rdfs:comment "An exposure to chlordecone." ;
rdfs:subClassOf obo:ECTO_0001152 , obo:ECTO_9000044 .
obo:MONDO_1030011 a rdfs:Class ;
rdfs:label "paroxysmal atrial fibrillation" ;
rdfs:comment "An atrial fibrillation disorder characterized by intermittent atrial fibrillation that lasts less than seven days from onset." ;
rdfs:subClassOf obo:MONDO_0004981 .
obo:MONDO_0024654 a rdfs:Class ;
rdfs:label "skull disorder" ;
rdfs:comment "A non-neoplastic or neoplastic disorder that affects structures of the skull." ;
rdfs:subClassOf obo:MONDO_0005381 .
obo:ECTO_0000001 a rdfs:Class ;
rdfs:label "exposure to radiation" ;
rdfs:comment "A exposure event involving the interaction of an exposure receptor to radiation." ;
rdfs:subClassOf obo:ECTO_8000000 .
obo:ECTO_9000284 a rdfs:Class ;
rdfs:label "exposure to organophosphorus compound" ;
rdfs:comment "An exposure to organophosphorus compound." ;
rdfs:subClassOf obo:ECTO_0000135 , obo:ECTO_9001227 .
obo:ECTO_0070155 a rdfs:Class ;
rdfs:label "exposure to walnuts via ingestion" ;
rdfs:comment "An exposure to walnut (raw) via ingestion." ;
rdfs:subClassOf obo:ECTO_0000015 .
obo:MONDO_0005089 a rdfs:Class ;
rdfs:label "sarcoma" ;
rdfs:comment "A usually aggressive malignant neoplasm of the soft tissue or bone. It arises from muscle, fat, fibrous tissue, bone, cartilage, and blood vessels. Sarcomas occur in both children and adults. The prognosis depends largely on the degree of differentiation (grade) of the neoplasm. Representative subtypes are liposarcoma, leiomyosarcoma, osteosarcoma, and chondrosarcoma." ;
rdfs:subClassOf obo:MONDO_0004992 .
obo:MONDO_0024582 a rdfs:Class ;
rdfs:label "male reproductive system neoplasm" ;
rdfs:comment "A benign, borderline, or malignant neoplasm that affects the male reproductive system. Representative examples include benign prostate phyllodes tumor, benign testicular Sertoli cell tumor, prostatic intraepithelial neoplasia, prostate carcinoma, testicular seminoma, and testicular embryonal carcinoma." ;
rdfs:subClassOf obo:MONDO_0003150 , obo:MONDO_0006054 .
obo:MONDO_0002977 a rdfs:Class ;
rdfs:label "autoimmune disorder of the nervous system" ;
rdfs:comment "A disorder characterized by the degeneration of the nervous system due to autoimmunity. Representative examples include multiple sclerosis, Guillain-Barre syndrome, and myasthenia gravis." ;
rdfs:subClassOf obo:MONDO_0005071 , obo:MONDO_0007179 .
obo:MONDO_0040732 a rdfs:Class ;
rdfs:label "Pseudomonas aeruginosa infectious disease" ;
rdfs:subClassOf obo:MONDO_0005141 .
obo:IAO_8000005 a rdfs:Class ;
rdfs:label "import ontology module"@en ;
rdfs:comment "A subset ontology module that is intended to be imported from another ontology."@en ;
rdfs:seeAlso ;
rdfs:subClassOf obo:IAO_8000006 .
obo:MONDO_0037847 a rdfs:Class ;
rdfs:label "vertebral joint disorder" ;
rdfs:comment "A disease that involves the intervertebral joint." ;
rdfs:subClassOf obo:MONDO_0000812 , obo:MONDO_0006816 .
obo:MONDO_0004860 a rdfs:Class ;
rdfs:label "vitreous disorder" ;
rdfs:comment "A disease involving the vitreous humor." ;
rdfs:subClassOf obo:MONDO_0044137 .
obo:ECTO_7000125 a rdfs:Class ;
rdfs:label "exposure to drinking water" ;
rdfs:comment "A exposure event involving the interaction of an exposure receptor to drinking water." ;
rdfs:subClassOf obo:ECTO_7000063 .
obo:MONDO_0006769 a rdfs:Class ;
rdfs:label "gastroparesis" ;
rdfs:comment "Paralysis of the muscles of the stomach wall resulting in delayed emptying of the gastric contents into the small intestine." ;
rdfs:subClassOf obo:MONDO_0001318 .
obo:MONDO_0011849 a rdfs:Class ;
rdfs:label "psoriatic arthritis" ;
rdfs:comment "Joint inflammation associated with psoriasis." ;
rdfs:subClassOf obo:MONDO_0002254 , obo:MONDO_0008383 .
obo:MONDO_0037254 a rdfs:Class ;
rdfs:label "transitional cell neoplasm" ;
rdfs:subClassOf obo:MONDO_0005626 .
obo:ECTO_7000118 a rdfs:Class ;
rdfs:label "exposure to ultrafine respirable suspended particulate matter" ;
rdfs:comment "A exposure event involving the interaction of an exposure receptor to ultrafine respirable suspended particulate matter." ;
rdfs:subClassOf obo:ECTO_7000117 .
obo:MONDO_0100233 a rdfs:Class ;
rdfs:label "long COVID-19" ;
rdfs:comment "A chronic disease triggered by acute COVID-19 infection that is characterized by persistent symptoms following the acute phase of the SARS-CoV-2 infection, which may include fatigue, coughing, dyspnea, clouding of mentation, sleep disturbances, exercise intolerance and autonomic symptoms including tachycardia upon mild exercise or standing, night sweats, temperature dysregulation, gastroparesis, constipation or loose stools, and peripheral vasoconstriction." ;
rdfs:subClassOf obo:MONDO_0100320 .
obo:MONDO_0020678 a rdfs:Class ;
rdfs:label "sensorineural hearing loss disorder" ;
rdfs:comment "Hearing loss in which the root cause lies in the inner ear or sensory organ (cochlea and associated structures) or the vestibulocochlear nerve (cranial nerve VIII)." ;
rdfs:subClassOf obo:MONDO_0005365 .
obo:MONDO_0045048 a rdfs:Class ;
rdfs:label "toxemia of pregnancy" ;
rdfs:comment "A pregnancy induced hypertensive state that occurs after 20 weeks of gestation characterized by an increase in blood pressure, along with body swelling and proteinuria." ;
rdfs:subClassOf obo:MONDO_0024664 .
obo:MONDO_0002491 a rdfs:Class ;
rdfs:label "substance abuse" ;
rdfs:comment "The use of a drug for a reason other than which it was intended or in a manner or in quantities other than directed." ;
rdfs:subClassOf obo:MONDO_0002494 .
obo:MONDO_0005137 a rdfs:Class ;
rdfs:label "nutritional disorder" ;
rdfs:comment "Any condition related to a disturbance between proper intake and utilization of nourishment." ;
rdfs:subClassOf obo:MONDO_7770008 .
obo:MONDO_0020598 a rdfs:Class ;
rdfs:label "malabsorption syndrome" ;
rdfs:comment "A syndrome resulting from the inadequate absorption of nutrients in the small intestine. Symptoms include abdominal pain, bloating, and diarrhea." ;
rdfs:subClassOf obo:MONDO_0005020 .
obo:MONDO_0004910 a rdfs:Class ;
rdfs:label "mitral valve prolapse" ;
rdfs:comment "A fairly common and often benign valvular heart disorder characterized by redundancy or hooding of mitral valve leaflets so that they prolapse into the left atrium, often causing mitral regurgitation. It is often a symptomless condition but may be marked by varied symptoms (e.g. chest pain, fatigue, dizziness, dyspnea, or palpitations) leading in some cases to endocarditis or ventricular tachycardia." ;
rdfs:subClassOf obo:MONDO_0003767 .
obo:MONDO_0002913 a rdfs:Class ;
rdfs:label "cerebellar neoplasm" ;
rdfs:comment "A benign or malignant (primary or metastatic) tumor involving the cerebellum. -- 2003" ;
rdfs:subClassOf obo:MONDO_0002427 , obo:MONDO_0021211 .
obo:MONDO_0005003 a rdfs:Class ;
rdfs:label "chronic pancreatitis" ;
rdfs:comment "A chronic inflammatory process causing damage and fibrosis of the pancreatic parenchyma. Signs and symptoms include abdominal pain, malabsorption and diabetes mellitus." ;
rdfs:subClassOf obo:MONDO_0004982 .
obo:MONDO_0011122 a rdfs:Class ;
rdfs:label "obesity disorder" ;
rdfs:comment "A disorder involving an excessive amount of body fat." ;
rdfs:subClassOf obo:MONDO_0003916 .
obo:MONDO_0011855 a rdfs:Class ;
rdfs:label "granular corneal dystrophy type II" ;
rdfs:comment "Type II granular corneal dystrophy (GCDII) is a rare form of stromal corneal dystrophy characterized by irregular-shaped well-demarcated granular deposits in the superficial central corneal stroma, and progressive visual impairment." ;
rdfs:subClassOf obo:MONDO_0000764 , obo:MONDO_0020213 .
obo:MONDO_0002242 a rdfs:Class ;
rdfs:label "coagulation protein disease" ;
rdfs:comment "Congenital or acquired deficiency of one of the coagulation factors. It results in bleeding." ;
rdfs:subClassOf obo:MONDO_0001531 .
obo:MONDO_0002547 a rdfs:Class ;
rdfs:label "nerve sheath neoplasm" ;
rdfs:comment "A benign or malignant neoplasm arising from the perineural cells in the sheaths surrounding the nerves. Representative examples include neurofibroma, schwannoma, and malignant peripheral nerve sheath tumor." ;
rdfs:subClassOf obo:MONDO_0001406 , obo:MONDO_0021042 .
obo:MONDO_0011057 a rdfs:Class ;
rdfs:label "cerebrovascular disorder" ;
rdfs:comment "A disorder resulting from inadequate blood flow in the vessels that supply the brain. Representative examples include cerebrovascular ischemia, cerebral embolism, and cerebral infarction." ;
rdfs:subClassOf obo:MONDO_0005560 , obo:MONDO_0043218 .
obo:MONDO_0002816 a rdfs:Class ;
rdfs:label "adrenal cortex disorder" ;
rdfs:comment "A disease involving the adrenal cortex." ;
rdfs:subClassOf obo:MONDO_0005495 .
obo:HP_0001654 a rdfs:Class ;
rdfs:label "Abnormal heart valve morphology" ;
rdfs:comment "Any structural abnormality of a cardiac valve." ;
rdfs:subClassOf obo:HP_0001627 .
obo:MONDO_0005079 a rdfs:Class ;
rdfs:label "polyp" ;
rdfs:comment "A usually exophytic mass attached to the underlying tissue by a broad base or a thin stalk. Polyps can be neoplastic or non-neoplastic. Neoplastic polyps usually represent proliferations of the epithelium, and are commonly seen in the gastrointestinal tract. Polyps of the gastrointestinal tract are often called adenomas, are associated with dysplasia, and may eventually transform into carcinomas. Non-neoplastic polyps may be inflammatory, degenerative, or the result of malformations." ;
rdfs:subClassOf obo:MONDO_0045024 .
obo:ECTO_0000726 a rdfs:Class ;
rdfs:label "exposure to allergen" ;
rdfs:comment "An exposure to allergen." ;
rdfs:subClassOf obo:ECTO_0000485 .
obo:MONDO_0021063 a rdfs:Class ;
rdfs:label "malignant colon neoplasm" ;
rdfs:comment "A primary or metastatic malignant neoplasm that affects the colon. Representative examples include carcinoma, lymphoma, and sarcoma." ;
rdfs:subClassOf obo:MONDO_0005401 , obo:MONDO_0005575 .
obo:MONDO_0005559 a rdfs:Class ;
rdfs:label "neurodegenerative disease" ;
rdfs:comment "A disorder of the central nervous system characterized by gradual and progressive loss of neural tissue and neurologic function." ;
rdfs:subClassOf obo:MONDO_0002602 .
obo:MONDO_8000010 a rdfs:Class ;
rdfs:label "antiphospholipid syndrome" ;
rdfs:comment "A disorder caused by the presence of autoantibodies directed against phospholipids, causing a hypercoaguable state, which may result in blood clots, stroke, heart attack, and in women, significant pregnancy-related complications, including miscarriage and still birth. The syndrome is often associated with other autoimmune disorders, most commonly lupus erythematosus, and infections, including syphilis and Lyme disease." ;
rdfs:subClassOf obo:MONDO_0002254 , obo:MONDO_0007179 .
obo:ECTO_6000039 a rdfs:Class ;
rdfs:label "exposure to Physical Activity" ;
rdfs:comment "An exposure event involving Physical Activity" ;
rdfs:subClassOf obo:ECTO_6000000 .
obo:MONDO_0021179 a rdfs:Class ;
rdfs:label "proteostasis deficiencies" ;
rdfs:comment "Disorders caused by imbalances in the protein homeostasis network - synthesis, folding, and transport of proteins; post-translational modifications; and degradation or clearance of misfolded proteins." ;
rdfs:subClassOf obo:MONDO_0005066 , obo:MONDO_7770011 .
obo:MONDO_0019338 a rdfs:Class ;
rdfs:label "sarcoidosis" ;
rdfs:comment "Sarcoidosis is a multisystemic disorder of unknown cause characterized by the formation of immune granulomas in involved organs." ;
rdfs:subClassOf obo:MONDO_0019751 .
obo:MONDO_0005065 a rdfs:Class ;
rdfs:label "mesothelioma" ;
rdfs:comment "A usually malignant and aggressive neoplasm of the mesothelium which is often associated with exposure to asbestos." ;
rdfs:subClassOf obo:MONDO_0006856 .
obo:MONDO_0003803 a rdfs:Class ;
rdfs:label "aortic valve disorder" ;
rdfs:comment "A disease involving the aortic valve." ;
rdfs:subClassOf obo:MONDO_0002869 , obo:MONDO_0005561 , obo:MONDO_0045001 .
obo:MONDO_0000649 a rdfs:Class ;
rdfs:label "sensory system cancer" ;
rdfs:comment "A malignant neoplasm involving the sensory system" ;
rdfs:subClassOf obo:MONDO_0005872 .
obo:HP_0030680 a rdfs:Class ;
rdfs:label "Abnormal cardiovascular system morphology" ;
rdfs:comment "Any structural anomaly of the heart and blood vessels." ;
rdfs:subClassOf obo:HP_0001626 .
obo:IAO_8000009 a rdfs:Class ;
rdfs:label "single layer subset ontology module"@en ;
rdfs:comment "A subset ontology that is largely comprised of a single layer or strata in an ontology class hierarchy. The purpose is typically for rolling up for visualization. The classes in the layer need not be disjoint."@en ;
rdfs:subClassOf obo:IAO_8000006 .
obo:MONDO_0021167 a rdfs:Class ;
rdfs:label "myositis disease" ;
rdfs:comment "An inflammatory disease involving a pathogenic inflammatory response in the muscle tissue." ;
rdfs:subClassOf obo:MONDO_0005336 , obo:MONDO_0021166 .
obo:MONDO_0005459 a rdfs:Class ;
rdfs:label "human African trypanosomiasis" ;
rdfs:comment "A parasitic disorder caused by protozoa of the Trypanosoma brucei species. It is transmitted by flies and is endemic in various regions of Sub-Saharan Africa. Signs and symptoms include fever, joint pain, headache, and significant swelling of the lymph nodes. If left untreated, the parasitic infection causes anemia, heart, kidney, and endocrine failure, and neurologic damage. Subsequently patients develop confusion, disruption of the sleep cycle, and mental deterioration. The infection may lead to coma and death." ;
rdfs:subClassOf obo:MONDO_0000940 , obo:MONDO_0100120 .
obo:IAO_0000102 a rdfs:Class ;
rdfs:label "data about an ontology part"@en ;
rdfs:comment "Data about an ontology part is a data item about a part of an ontology, for example a term"@en ;
rdfs:subClassOf obo:IAO_0000027 .
obo:MONDO_0021698 a rdfs:Class ;
rdfs:label "alcohol-related disorders" ;
rdfs:comment "Disorders related to or resulting from abuse or mis-use of alcohol." ;
rdfs:subClassOf obo:MONDO_0002494 .
obo:MONDO_7770010 a rdfs:Class ;
rdfs:label "disease of primarily extrinsic mechanism" ;
rdfs:comment "A grouping class for human diseases caused primarily by extrinsic factors, including infections, toxins, nutritional deficiencies, iatrogenic causes, and environmental exposures." ;
rdfs:subClassOf obo:MONDO_7770008 .
obo:IAO_8000004 a rdfs:Class ;
rdfs:label "bridge ontology module"@en ;
rdfs:comment "An ontology module that consists entirely of axioms that connect or bridge two distinct ontology modules. For example, the Uberon-to-ZFA bridge module."@en ;
rdfs:seeAlso ;
rdfs:subClassOf obo:IAO_8000000 .
obo:MONDO_0018202 a rdfs:Class ;
rdfs:label "gonadal germ cell tumor" ;
rdfs:subClassOf obo:MONDO_0005040 .
obo:MONDO_0005140 a rdfs:Class ;
rdfs:label "ovarian carcinoma" ;
rdfs:comment "A malignant neoplasm originating from the surface ovarian epithelium. It accounts for the greatest number of deaths from malignancies of the female genital tract and is the fifth leading cause of cancer fatalities in women. It is predominantly a disease of older white women of northern European extraction, but it is seen in all ages and ethnic groups. Adenocarcinomas constitute the vast majority of ovarian carcinomas. The pattern of metastatic spread in ovarian carcinoma is similar regardless of the microscopic type. The most common sites of involvement are the contralateral ovary, peritoneal cavity, para-aortic and pelvic lymph nodes, and liver. Lung and pleura are the most common sites of extra-abdominal spread. The primary form of therapy is surgical. The overall prognosis of ovarian carcinoma remains poor, a direct result of its rapid growth rate and the lack of early symptoms. --2002" ;
rdfs:subClassOf obo:MONDO_0018364 .
obo:MONDO_0018881 a rdfs:Class ;
rdfs:label "myelodysplastic syndrome" ;
rdfs:comment "A clonal hematopoietic disorder characterized by dysplasia and ineffective hematopoiesis in one or more of the hematopoietic cell lines. The dysplasia may be accompanied by an increase in myeloblasts, but the number is less than 20%, which, according to the WHO guidelines, is the requisite threshold for the diagnosis of acute myeloid leukemia. It may occur de novo or as a result of exposure to alkylating agents and/or radiotherapy. (WHO, 2001)" ;
rdfs:subClassOf obo:MONDO_0015756 , obo:MONDO_0021058 .
obo:MONDO_0006615 a rdfs:Class ;
rdfs:label "sweat gland disorder" ;
rdfs:comment "A disease involving the sweat gland." ;
rdfs:subClassOf obo:MONDO_0005093 .
obo:MONDO_0001569 a rdfs:Class ;
rdfs:label "acoustic neuroma" ;
rdfs:comment "A type of benign brain tumor that begins in the Schwann cells, which produce the myelin that protects the acoustic nerve - the nerve of hearing." ;
rdfs:subClassOf obo:MONDO_0002546 .
obo:MONDO_0021345 a rdfs:Class ;
rdfs:label "carcinoma of pharynx" ;
rdfs:comment "A carcinoma that involves the pharynx." ;
rdfs:subClassOf obo:MONDO_0006181 , obo:MONDO_0021246 .
obo:MONDO_0005249 a rdfs:Class ;
rdfs:label "pneumonia" ;
rdfs:comment "An acute, acute and chronic, or chronic inflammation focally or diffusely affecting the lung parenchyma, caused by an infection in one or both of the lungs (by bacteria, viruses, fungi, or mycoplasma.). Symptoms include cough, shortness of breath, fevers, chills, chest pain, headache, sweating, and weakness." ;
rdfs:subClassOf obo:MONDO_0024355 , obo:MONDO_0043905 .
obo:MONDO_0001104 a rdfs:Class ;
rdfs:label "toxic diffuse goiter" ;
rdfs:subClassOf obo:MONDO_0004425 , obo:MONDO_0005397 .
obo:MONDO_0003937 a rdfs:Class ;
rdfs:label "spondylitis" ;
rdfs:comment "The inflammation of a vertebra." ;
rdfs:subClassOf obo:MONDO_0021166 , obo:MONDO_0045002 .
obo:ECTO_1000020 a rdfs:Class ;
rdfs:label "exposure to weather" ;
rdfs:comment "A exposure event involving the interaction of an exposure receptor to the condition of weather." ;
rdfs:subClassOf obo:ECTO_1000000 .
obo:MONDO_0003620 a rdfs:Class ;
rdfs:label "peripheral nervous system disorder" ;
rdfs:comment "A disease involving the peripheral nervous system." ;
rdfs:subClassOf obo:MONDO_0005071 .
obo:MONDO_0012268 a rdfs:Class ;
rdfs:label "AIDS" ;
rdfs:comment "A syndrome resulting from the acquired deficiency of cellular immunity caused by the human immunodeficiency virus (HIV). It is characterized by the reduction of the Helper T-lymphocytes in the peripheral blood and the lymph nodes. Symptoms include generalized lymphadenopathy, fever, weight loss, and chronic diarrhea. Patients with AIDS are especially susceptible to opportunistic infections (usually pneumocystis carinii pneumonia, cytomegalovirus (CMV) infections, tuberculosis, candida infections, and cryptococcosis), and the development of malignant neoplasms (usually non-Hodgkin lymphoma and Kaposi sarcoma). The human immunodeficiency virus is transmitted through sexual contact, sharing of contaminated needles, or transfusion of contaminated blood." ;
rdfs:subClassOf obo:MONDO_0003780 , obo:MONDO_0005109 .
obo:HP_0003202 a rdfs:Class ;
rdfs:label "Skeletal muscle atrophy" ;
rdfs:comment "The presence of skeletal muscular atrophy (which is also known as amyotrophy)." ;
rdfs:subClassOf obo:HP_0011805 .
obo:ECTO_0070218 a rdfs:Class ;
rdfs:label "exposure to sodium chloride food material via ingestion" ;
rdfs:comment "An exposure to sodium chloride food material via ingestion." ;
rdfs:subClassOf obo:ECTO_0000015 .
obo:MONDO_0002428 a rdfs:Class ;
rdfs:label "protozoa infectious disease" ;
rdfs:comment "An infection that is caused by protozoans." ;
rdfs:subClassOf obo:MONDO_0005135 .
obo:MONDO_0004846 a rdfs:Class ;
rdfs:label "placental abruption" ;
rdfs:comment "Vaginal bleeding preceding the 20th week of gestation." ;
rdfs:subClassOf obo:MONDO_0005917 .
obo:MONDO_0002567 a rdfs:Class ;
rdfs:label "tracheal disorder" ;
rdfs:comment "A non-neoplastic or neoplastic disorder that affects the trachea. Representative examples of non-neoplastic disorders include congenital malformations and infection. Representative examples of neoplastic disorders include carcinoma and lymphoma." ;
rdfs:subClassOf obo:MONDO_0000270 , obo:MONDO_0004867 .
obo:ECTO_0000231 a rdfs:Class ;
rdfs:label "exposure to chemical" ;
rdfs:comment "An exposure to chemical entity." ;
rdfs:subClassOf obo:ExO_0000002 .
obo:MONDO_0005206 a rdfs:Class ;
rdfs:label "renal carcinoma" ;
rdfs:comment "A carcinoma arising from the epithelium of the renal parenchyma or the renal pelvis. The majority are renal cell carcinomas. Kidney carcinomas usually affect middle aged and elderly adults. Hematuria, abdominal pain, and a palpable mass are common symptoms." ;
rdfs:subClassOf obo:MONDO_0002367 , obo:MONDO_0004993 .
obo:MONDO_0005626 a rdfs:Class ;
rdfs:label "epithelial neoplasm" ;
rdfs:comment "A benign or malignant neoplasm that arises from and is composed of epithelial cells. This category include adenomas, papillomas, and carcinomas." ;
rdfs:subClassOf obo:MONDO_0005070 .
obo:HP_0033401 a rdfs:Class ;
rdfs:label "Tissue ischemia" ;
rdfs:comment "Ischemia is defined as a restriction of arterial blood supply to a tissue associated with insufficient oxygenation to support the metabolis requirements of the tissue. Depending on the involved tissues, clinical manifestations may include pain, pallor, lack of pulse, coldness, paresthesia, and paralysis. Additional associated manifestations include hemodynamic parameters (reduced blood pressure distal to the site of restricted arterial supply) and angiographic evidence of arterial occclusion." ;
rdfs:subClassOf obo:HP_0025323 .
obo:HP_0010978 a rdfs:Class ;
rdfs:label "Abnormality of immune system physiology" ;
rdfs:comment "A functional abnormality of the immune system." ;
rdfs:subClassOf obo:HP_0002715 .
obo:ECTO_9000068 a rdfs:Class ;
rdfs:label "exposure to polychlorobiphenyl" ;
rdfs:comment "An exposure to polychlorobiphenyl." ;
rdfs:subClassOf obo:ECTO_9001537 , obo:ECTO_9002155 .
obo:MONDO_0043424 a rdfs:Class ;
rdfs:label "digestive system infectious disorder" ;
rdfs:comment "A viral, bacterial, fungal, or parasitic infectious process that affects the digestive system." ;
rdfs:subClassOf obo:MONDO_0004335 , obo:MONDO_0005550 .
obo:MONDO_0005279 a rdfs:Class ;
rdfs:label "pulmonary embolism" ;
rdfs:comment "The obstruction of the pulmonary artery or one of its branches by an embolus, sometimes associated with infarction of the lung." ;
rdfs:subClassOf obo:MONDO_0000473 .
obo:MONDO_0008383 a rdfs:Class ;
rdfs:label "rheumatoid arthritis" ;
rdfs:comment "A chronic, systemic autoimmune disorder characterized by inflammation in the synovial membranes and articular surfaces. It manifests primarily as a symmetric, erosive polyarthritis that spares the axial skeleton and is typically associated with the presence in the serum of rheumatoid factor." ;
rdfs:subClassOf obo:MONDO_0000589 , obo:MONDO_0005554 , obo:MONDO_0005578 .
obo:MONDO_0005100 a rdfs:Class ;
rdfs:label "systemic sclerosis" ;
rdfs:comment "A chronic disorder, possibly autoimmune, marked by excessive production of collagen which results in hardening and thickening of body tissues. The two types of systemic scleroderma, limited cutaneous and diffuse cutaneous are classified with focus on the extent of affected skin. A relationship exists between the extent of skin area affected and degree of internal organ/system involvement. Systemic scleroderma can manifest itself in pulmonary fibrosis, Raynaud's syndrome, digestive system telangiectasias, renal hypertension and/or pulmonary hypertension." ;
rdfs:subClassOf obo:MONDO_0005093 , obo:MONDO_0019340 .
obo:ECTO_0900056 a rdfs:Class ;
rdfs:label "exposure to nutrient via ingestion" ;
rdfs:comment "An exposure to nutrient via ingestion route." ;
rdfs:subClassOf obo:ECTO_0900120 , obo:ECTO_9001695 .
obo:MONDO_0008315 a rdfs:Class ;
rdfs:label "prostate cancer" ;
rdfs:comment "A primary or metastatic malignant tumor involving the prostate gland. The vast majority are carcinomas." ;
rdfs:subClassOf obo:MONDO_0005836 , obo:MONDO_0021259 .
obo:HP_0007379 a rdfs:Class ;
rdfs:label "Neoplasm of the genitourinary tract" ;
rdfs:comment "A tumor (abnormal growth of tissue) of the genitourinary system." ;
rdfs:subClassOf obo:HP_0000119 , obo:HP_0011793 .
obo:MONDO_0006901 a rdfs:Class ;
rdfs:label "peritoneal neoplasm" ;
rdfs:comment "A benign or malignant neoplasm that affects the peritoneal cavity. Representative examples of benign neoplasms include adenomatoid tumor and disseminated peritoneal leiomyomatosis. Representative examples of malignant neoplasms include primary peritoneal carcinoma, metastatic carcinoma to the peritoneum, and malignant mesothelioma." ;
rdfs:subClassOf obo:MONDO_0005070 .
obo:MONDO_0024633 a rdfs:Class ;
rdfs:label "hypertensive nephropathy" ;
rdfs:comment "Kidney damage that results from chronically elevated blood pressure; complications include glomerular damage resulting in proteinuria and hematuria." ;
rdfs:subClassOf obo:MONDO_0005240 .
obo:MONDO_0004805 a rdfs:Class ;
rdfs:label "leukocyte disorder" ;
rdfs:comment "A disease involving leukocytes." ;
rdfs:subClassOf obo:MONDO_0005046 , obo:MONDO_0005570 .
obo:MONDO_0004970 a rdfs:Class ;
rdfs:label "adenocarcinoma" ;
rdfs:comment "A common cancer characterized by the presence of malignant glandular cells. Morphologically, adenocarcinomas are classified according to the growth pattern (e.g., papillary, alveolar) or according to the secreting product (e.g., mucinous, serous). Representative examples of adenocarcinoma are ductal and lobular breast carcinoma, lung adenocarcinoma, renal cell carcinoma, hepatocellular carcinoma (hepatoma), colon adenocarcinoma, and prostate adenocarcinoma." ;
rdfs:subClassOf obo:MONDO_0004993 , obo:MONDO_0024276 .
obo:MONDO_0004375 a rdfs:Class ;
rdfs:label "end stage renal failure" ;
rdfs:comment "Long-standing and persistent renal disease with glomerular filtration rate (GFR) less than 15 ml/min." ;
rdfs:subClassOf obo:MONDO_0005300 .
obo:MONDO_0006626 a rdfs:Class ;
rdfs:label "diabetic neuropathy" ;
rdfs:comment "A chronic, pathological complication associated with diabetes mellitus, where nerve damages are incurred due to diabetic microvascular injury involving small blood vessels that supply these nerves, resulting in peripheral and/or autonomic nerve dysfunction." ;
rdfs:subClassOf obo:MONDO_0005244 .
obo:HP_0100545 a rdfs:Class ;
rdfs:label "Arterial stenosis" ;
rdfs:comment "Narrowing or constriction of the inner surface (lumen) of an artery." ;
rdfs:subClassOf obo:HP_0011004 .
obo:ECTO_8000054 a rdfs:Class ;
rdfs:label "exposure to radiowave radiation" ;
rdfs:comment "A exposure event involving the interaction of an exposure receptor to radio wave radiation." ;
rdfs:subClassOf obo:ECTO_0000002 .
obo:ECTO_0070204 a rdfs:Class ;
rdfs:label "exposure to cow milk (liquid) via ingestion" ;
rdfs:comment "An exposure to cow milk (liquid) via ingestion." ;
rdfs:subClassOf obo:ECTO_0000015 .
obo:ECTO_7000114 a rdfs:Class ;
rdfs:label "exposure to aerosol" ;
rdfs:comment "A exposure event involving the interaction of an exposure receptor to aerosol." ;
rdfs:subClassOf obo:ECTO_0000015 .
obo:MONDO_0004580 a rdfs:Class ;
rdfs:label "retinal degeneration" ;
rdfs:comment "Degeneration of the retina." ;
rdfs:subClassOf obo:MONDO_0005283 .
obo:MONDO_0005549 a rdfs:Class ;
rdfs:label "renal cell adenocarcinoma" ;
rdfs:comment "A carcinoma arising from the renal parenchyma. There is a strong correlation between cigarette smoking and the development of renal cell carcinoma. The clinical presentation includes : hematuria, flank pain and a palpable lumbar mass. A high percentage of renal cell carcinomas are diagnosed when an ultrasound is performed for other purposes. Radical nephrectomy is the standard intervention procedure. Renal cell carcinoma is generally considered to be resistant to radiation treatment and chemotherapy." ;
rdfs:subClassOf obo:MONDO_0005086 .
obo:PATO_0000001 a rdfs:Class ;
rdfs:label "quality" ;
rdfs:comment "A dependent entity that inheres in a bearer by virtue of how the bearer is related to other entities" ;
rdfs:subClassOf obo:BFO_0000020 .
obo:MONDO_0006295 a rdfs:Class ;
rdfs:label "malignant urinary system neoplasm" ;
rdfs:comment "A primary or metastatic malignant tumor involving the urinary system. Common tumor types include carcinomas, lymphomas, and sarcomas." ;
rdfs:subClassOf obo:MONDO_0004992 , obo:MONDO_0021066 .
obo:MONDO_0006011 a rdfs:Class ;
rdfs:label "viral hepatitis" ;
rdfs:comment "An acute or chronic inflammation of the liver parenchyma caused by viruses. Representative examples include hepatitis A, B, and C, cytomegalovirus hepatitis, and herpes simplex hepatitis." ;
rdfs:subClassOf obo:MONDO_0002251 , obo:MONDO_0043424 , obo:MONDO_0100329 .
obo:MONDO_0007915 a rdfs:Class ;
rdfs:label "systemic lupus erythematosus" ;
rdfs:comment "An autoimmune multi-organ disease typically associated with vasculopathy and autoantibody production. Most patients have antinuclear antibodies (ANA). The presence of anti-dsDNA or anti-Smith antibodies are highly-specific." ;
rdfs:subClassOf obo:MONDO_0004670 , obo:MONDO_0023603 .
obo:MONDO_0005076 a rdfs:Class ;
rdfs:label "periodontitis" ;
rdfs:comment "An acute or chronic inflammatory process that affects the tissues that surround and support the teeth." ;
rdfs:subClassOf obo:MONDO_0002635 , obo:MONDO_0021166 .
obo:ECTO_9000271 a rdfs:Class ;
rdfs:label "exposure to alkaloid" ;
rdfs:comment "An exposure to alkaloid." ;
rdfs:subClassOf obo:ECTO_9000190 .
obo:MONDO_7770008 a rdfs:Class ;
rdfs:label "disease by etiologic mechanism" ;
rdfs:comment "A grouping class for human diseases classified by their etiologic mechanism, encompassing primarily intrinsic (genetic, genomic), primarily extrinsic (e.g., infections, toxins, radiation), and complex multifactorial (e.g. nutritional) causes." ;
rdfs:subClassOf obo:MONDO_0700096 .
obo:MONDO_0013209 a rdfs:Class ;
rdfs:label "metabolic dysfunction-associated steatotic liver disease" ;
rdfs:comment "Metabolic dysfunction-associated steatotic liver disease (MASLD, formerly known as nonalcoholic fatty liver disease or NAFLD) is a type of liver disease that is not caused by alcohol. It typically does not cause symptoms in the early stages, but it can cause health problems due to fat accumulation, inflammation, and scarring in the liver." ;
rdfs:subClassOf obo:MONDO_0004790 .
obo:MONDO_0021094 a rdfs:Class ;
rdfs:label "immunodeficiency disease" ;
rdfs:comment "Disease in which there is a deficiency or defect in the mechanisms of immunity, either cellular or humoral." ;
rdfs:subClassOf obo:MONDO_0003847 , obo:MONDO_0005046 .
obo:MONDO_0005059 a rdfs:Class ;
rdfs:label "leukemia" ;
rdfs:comment "A malignant (clonal) hematologic disorder, involving hematopoietic stem cells and characterized by the presence of primitive or atypical myeloid or lymphoid cells in the bone marrow and the blood. Leukemias are classified as acute or chronic based on the degree of cellular differentiation and the predominant cell type present. Leukemia is usually associated with anemia, fever, hemorrhagic episodes, and splenomegaly. Common leukemias include acute myeloid leukemia, chronic myelogenous leukemia, acute lymphoblastic or precursor lymphoblastic leukemia, and chronic lymphocytic leukemia. Treatment is vital to patient survival; untreated, the natural course of acute leukemias is normally measured in weeks or months, while that of chronic leukemias is more often measured in months or years." ;
rdfs:subClassOf obo:MONDO_0044881 .
obo:HP_0020129 a rdfs:Class ;
rdfs:label "Abnormal urine protein level" ;
rdfs:comment "Any deviation of the concentration of one or more proteins in the urine." ;
rdfs:subClassOf obo:HP_0033354 .
obo:MONDO_0005011 a rdfs:Class ;
rdfs:label "Crohn disease" ;
rdfs:comment "A gastrointestinal disorder characterized by chronic inflammation involving all layers of the intestinal wall, noncaseating granulomas affecting the intestinal wall and regional lymph nodes, and transmural fibrosis. Crohn disease most commonly involves the terminal ileum; the colon is the second most common site of involvement." ;
rdfs:subClassOf obo:MONDO_0005265 .
obo:MONDO_0015756 a rdfs:Class ;
rdfs:label "myeloid hemopathy" ;
rdfs:subClassOf obo:MONDO_0002334 .
obo:MONDO_7770003 a rdfs:Class ;
rdfs:label "cystic fibrosis-related diabetes" ;
rdfs:comment "A form of diabetes mellitus unique to individuals with cystic fibrosis (CF), arising primarily from progressive fibrotic destruction of the pancreas leading to insulin deficiency, with additional contributions from insulin resistance. CFRD affects approximately 20% of adolescents and 40-50% of adults with CF. It shares features with both type 1 and type 2 diabetes but is a distinct clinical entity with its own diagnostic criteria and management guidelines." ;
rdfs:subClassOf obo:MONDO_0005015 .
obo:MONDO_0002659 a rdfs:Class ;
rdfs:label "uveal cancer" ;
rdfs:comment "A primary or metastatic malignant neoplasm that affects the choroid, ciliary body, or iris." ;
rdfs:subClassOf obo:MONDO_0002236 , obo:MONDO_0021225 .
obo:MONDO_0003219 a rdfs:Class ;
rdfs:label "gastroesophageal junction adenocarcinoma" ;
rdfs:comment "A carcinoma that arises from glandular epithelial cells of the esophagogastric junction." ;
rdfs:subClassOf obo:MONDO_0004970 , obo:MONDO_0006181 .
obo:MONDO_0005336 a rdfs:Class ;
rdfs:label "myopathy" ;
rdfs:comment "A disease of the muscle in which the muscle fibers do not function properly. This results in muscular weakness." ;
rdfs:subClassOf obo:MONDO_0020120 .
obo:MONDO_0005202 a rdfs:Class ;
rdfs:label "atopic IgE-mediated allergic disorder" ;
rdfs:comment "A genetic predisposition to form IgE antibodies in response to exposure to allergens and therefore, for the development of immediate (type I) hypersensitivity and atopic conditions, such as allergic rhinitis; bronchial asthma, atopic dermatitis, and food allergy. Mutations of specific alleles on the long arm of chromosome 5 have been associated with higher levels of IL-4 and IgE and are known as IL-4 promoter polymorphisms." ;
rdfs:subClassOf obo:MONDO_0005271 .
obo:MONDO_0003996 a rdfs:Class ;
rdfs:label "basal ganglia disorder" ;
rdfs:comment "A disease involving the basal ganglia." ;
rdfs:subClassOf obo:MONDO_0005560 .
obo:HP_0001507 a rdfs:Class ;
rdfs:label "Growth abnormality" ;
rdfs:subClassOf obo:HP_0000118 .
obo:HP_0007364 a rdfs:Class ;
rdfs:label "Aplasia/Hypoplasia of the cerebrum" ;
rdfs:subClassOf obo:HP_0002060 , obo:HP_0002977 .
obo:MONDO_0005375 a rdfs:Class ;
rdfs:label "nasopharyngeal neoplasm" ;
rdfs:comment "A benign or malignant neoplasm affecting the nasopharynx. Representative examples of benign neoplasms include angiofibroma and squamous papilloma. Representative examples of malignant neoplasms include keratinizing squamous cell carcinoma and nonkeratinizing carcinoma." ;
rdfs:subClassOf obo:MONDO_0004821 , obo:MONDO_0005586 , obo:MONDO_0020641 , obo:MONDO_0021246 .
obo:MONDO_0004670 a rdfs:Class ;
rdfs:label "lupus erythematosus" ;
rdfs:comment "An autoimmune, connective tissue chronic inflammatory disorder affecting the skin, joints, kidneys, lungs, heart, and the peripheral blood cells. It is more commonly seen in women than men. Variants include discoid and systemic lupus erythematosus." ;
rdfs:subClassOf obo:MONDO_0005554 , obo:MONDO_0007179 .
obo:MONDO_0005494 a rdfs:Class ;
rdfs:label "triple-negative breast carcinoma" ;
rdfs:comment "An invasive breast carcinoma which is negative for expression of estrogen receptor (ER), progesterone receptor (PR), and human epidermal growth factor receptor 2 (HER2)." ;
rdfs:subClassOf obo:MONDO_0000616 , obo:MONDO_0000618 , obo:MONDO_0006513 .
obo:MONDO_0044339 a rdfs:Class ;
rdfs:label "lumbar disk degenerative disorder" ;
rdfs:comment "Any degenerative disorder affecting one or more vertebral disks of the lumbar spine." ;
rdfs:subClassOf obo:MONDO_0011385 .
obo:MONDO_0005876 a rdfs:Class ;
rdfs:label "Nidovirales infectious disease" ;
rdfs:comment "Infections with viruses of the order nidovirales. The concept includes arterivirus infections and coronaviridae infections." ;
rdfs:subClassOf obo:MONDO_0100329 .
obo:MONDO_0003105 a rdfs:Class ;
rdfs:label "prostate disorder" ;
rdfs:comment "A disease involving the prostate gland." ;
rdfs:subClassOf obo:MONDO_0003150 .
obo:MONDO_0002898 a rdfs:Class ;
rdfs:label "skin cancer" ;
rdfs:comment "A malignant neoplasm involving the zone of skin" ;
rdfs:subClassOf obo:MONDO_0000653 , obo:MONDO_0002531 .
obo:MONDO_0005365 a rdfs:Class ;
rdfs:label "hearing loss disorder" ;
rdfs:comment "A partial or complete loss of hearing in one or both ears. It is classified as conductive, sensory, or central." ;
rdfs:subClassOf obo:MONDO_0021945 .
obo:MONDO_0041526 a rdfs:Class ;
rdfs:label "pregnancy disorder with abortive outcome" ;
rdfs:subClassOf obo:MONDO_0024575 .
obo:MONDO_0004947 a rdfs:Class ;
rdfs:label "B-cell acute lymphoblastic leukemia" ;
rdfs:comment "A neoplasm of lymphoblasts committed to the B-cell lineage, typically composed of small to medium-sized blast cells. When the neoplasm involves predominantly the bone marrow and the peripheral blood, it is called B acute lymphoblastic leukemia. When it involves nodal or extranodal sites, it is called B lymphoblastic lymphoma. (WHO, 2001)" ;
rdfs:subClassOf obo:MONDO_0004967 , obo:MONDO_0015759 .
obo:ECTO_9002053 a rdfs:Class ;
rdfs:label "exposure to persistent organic pollutant" ;
rdfs:comment "An exposure to persistent organic pollutant." ;
rdfs:subClassOf obo:ECTO_0000931 .
obo:HP_0004755 a rdfs:Class ;
rdfs:label "Supraventricular tachycardia" ;
rdfs:comment "Supraventricular tachycardia (SVT) is an abnormally increased heart rate (over 100 beats per minute at rest) with origin above the level of the ventricles." ;
rdfs:subClassOf obo:HP_0001649 , obo:HP_0005115 .
obo:MONDO_0005393 a rdfs:Class ;
rdfs:label "gout" ;
rdfs:comment "A condition characterized by painful swelling of the joints, which is caused by deposition of urate crystals." ;
rdfs:subClassOf obo:MONDO_0005066 .
obo:MONDO_0016663 a rdfs:Class ;
rdfs:label "overlapping connective tissue disease" ;
rdfs:subClassOf obo:MONDO_0003900 , obo:MONDO_0007179 .
obo:MONDO_0037748 a rdfs:Class ;
rdfs:label "hyperlipoproteinemia" ;
rdfs:comment "An elevated concentration of lipoproteins." ;
rdfs:subClassOf obo:MONDO_0005066 .
obo:MONDO_0004976 a rdfs:Class ;
rdfs:label "amyotrophic lateral sclerosis" ;
rdfs:comment "Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease characterized by progressive muscular paralysis reflecting degeneration of motor neurons in the primary motor cortex, corticospinal tracts, brainstem and spinal cord." ;
rdfs:subClassOf obo:MONDO_0003182 , obo:MONDO_0020128 .
obo:MONDO_0007079 a rdfs:Class ;
rdfs:label "alcohol dependence" ;
rdfs:comment "Physical and psychological dependence on alcohol." ;
rdfs:subClassOf obo:MONDO_0005303 , obo:MONDO_0021698 .
obo:ECTO_2000065 a rdfs:Class ;
rdfs:label "exposure to calorie restrictive diet intake" ;
rdfs:comment "An exposure to calorie restrictive diet intake." ;
rdfs:subClassOf obo:ECTO_2000068 .
obo:ECTO_0900090 a rdfs:Class ;
rdfs:label "exposure to nicotinamide via ingestion" ;
rdfs:comment "An exposure to nicotinamide via ingestion route." ;
rdfs:subClassOf obo:ECTO_0900029 , obo:ECTO_0900477 , obo:ECTO_9002478 .
obo:IAO_8000019 a rdfs:Class ;
rdfs:label "ontology module subsetted by OWL profile"@en ;
rdfs:subClassOf obo:IAO_8000017 .
obo:MONDO_0004987 a rdfs:Class ;
rdfs:label "urinary bladder neoplasm" ;
rdfs:comment "A benign or malignant, primary or metastatic neoplasm of the bladder. - 2003" ;
rdfs:subClassOf obo:MONDO_0006026 , obo:MONDO_0021066 .
obo:MONDO_0016691 a rdfs:Class ;
rdfs:label "pilocytic astrocytoma" ;
rdfs:comment "Pilocytic astrocytoma is a rare subtype of low-grade glioma of the central nervous system characterized by a well circumscribed, often cystic, brain tumor with a discrete mural nodule and long, hair-like projections that extend from the neoplastic astrocytes. Depending on the primary localization and the size of the tumor, patients can present with signs of raised intracranial pressure (headache, vomiting, papilledema), blurred vision, decreased visual acuity, ataxia and/or nystagmus, among others. It is most commonly located in the cerebellum, but occurrence in the hypothalamus, brain stem, optic chiasma, and hemispheres has also been reported." ;
rdfs:subClassOf obo:MONDO_0016685 .
obo:MONDO_0008487 a rdfs:Class ;
rdfs:label "polycystic ovary syndrome" ;
rdfs:comment "A disorder that manifests as multiple cysts on the ovaries. It results in hormonal imbalances and leads to irregular and abnormal menstrual periods, excess growth of hair, acne eruptions and obesity." ;
rdfs:subClassOf obo:MONDO_0002254 , obo:MONDO_0003847 , obo:MONDO_0005151 .
obo:MONDO_0044991 a rdfs:Class ;
rdfs:label "upper digestive tract disorder" ;
rdfs:comment "A disease or disorder that involves the upper digestive tract." ;
rdfs:subClassOf obo:MONDO_0004335 .
obo:MONDO_0011962 a rdfs:Class ;
rdfs:label "endometrial cancer" ;
rdfs:comment "Primary or metastatic malignant neoplasm involving the endometrium (mucous membrane that lines the endometrial cavity)." ;
rdfs:subClassOf obo:MONDO_0002715 , obo:MONDO_0021251 .
obo:HP_0000716 a rdfs:Class ;
rdfs:label "Depression" ;
rdfs:comment "Frequently experiencing feelings of being down, miserable, and/or hopeless; struggling to recover from these moods; having a pessimistic outlook on the future; feeling a pervasive sense of shame; having a low self-worth; experiencing thoughts of suicide and engaging in suicidal behavior." ;
rdfs:subClassOf obo:HP_0000745 , obo:HP_0100851 .
obo:MONDO_0005145 a rdfs:Class ;
rdfs:label "sporadic amyotrophic lateral sclerosis" ;
rdfs:comment "Sporadic amyotrophic lateral sclerosis is a amyotrophic lateral sclerosis in which there is no known cause, such as no family history." ;
rdfs:subClassOf obo:MONDO_0004976 .
obo:ECTO_9002148 a rdfs:Class ;
rdfs:label "exposure to polycyclic hydrocarbon" ;
rdfs:comment "An exposure to polycyclic hydrocarbon." ;
rdfs:subClassOf obo:ECTO_0000163 .
obo:MONDO_0003834 a rdfs:Class ;
rdfs:label "gastric cardia carcinoma" ;
rdfs:comment "A carcinoma that arises from epithelial cells of the cardia of stomach." ;
rdfs:subClassOf obo:MONDO_0001063 , obo:MONDO_0004950 .
obo:ECTO_0900120 a rdfs:Class ;
rdfs:label "exposure to food component via ingestion" ;
rdfs:comment "An exposure to food component via ingestion route." ;
rdfs:subClassOf obo:ECTO_9002063 .
obo:HP_0002060 a rdfs:Class ;
rdfs:label "Abnormal cerebral morphology" ;
rdfs:comment "Any structural abnormality of the telencephalon, which is also known as the cerebrum." ;
rdfs:subClassOf obo:HP_0100547 .
obo:MONDO_0017181 a rdfs:Class ;
rdfs:label "hypnic headache" ;
rdfs:comment "Conditions in which the primary symptom is headache and the headache cannot be attributed to any known causes." ;
rdfs:subClassOf obo:MONDO_0021146 .
a rdfs:Class ;
rdfs:label "temporary unclassified"@en ;
rdfs:comment "A holding class for a cohort individual that has not yet been classified as a cohort or a cohort aggregation. Nothing should remain here."@en .
obo:MONDO_0002305 a rdfs:Class ;
rdfs:label "thrombophilia" ;
rdfs:comment "A condition characterized by an abnormally high level of thrombi. Causes include thrombotic thrombocytopenic purpura, disseminated intravascular coagulation, bone marrow disorders, and antiphospholipid antibody syndrome." ;
rdfs:subClassOf obo:MONDO_0001531 .
obo:ECTO_6000002 a rdfs:Class ;
rdfs:label "exposure to exercise" ;
rdfs:comment "An exposure event involving Exercise" ;
rdfs:subClassOf obo:ECTO_6000039 .
obo:ECTO_0010003 a rdfs:Class ;
rdfs:label "exposure to environmental physical object quality" ;
rdfs:comment "A exposure event involving the interaction of an exposure receptor to physical object quality." ;
rdfs:subClassOf obo:ECTO_0010000 .
obo:MONDO_0005030 a rdfs:Class ;
rdfs:label "fetal growth restriction" ;
rdfs:comment "A fetus that does not grow beyond the 10th percentile of conventionally accepted weight for gestational age." ;
rdfs:subClassOf obo:MONDO_0005917 .
obo:ECTO_0800002 a rdfs:Class ;
rdfs:label "exposure to air pollution via maternal" ;
rdfs:comment "A exposure event involving the interaction of an exposure receptor to air pollution happening in maternal of the receptor." ;
rdfs:subClassOf obo:ECTO_0800001 , obo:ECTO_8000036 .
obo:MONDO_0004992 a rdfs:Class ;
rdfs:label "cancer" ;
rdfs:comment "A tumor composed of atypical neoplastic, often pleomorphic cells that invade other tissues. Malignant neoplasms often metastasize to distant anatomic sites and may recur after excision. The most common malignant neoplasms are carcinomas (adenocarcinomas or squamous cell carcinomas), Hodgkin and non-Hodgkin lymphomas, leukemias, melanomas, and sarcomas." ;
rdfs:subClassOf obo:MONDO_0005070 .
obo:MONDO_0000588 a rdfs:Class ;
rdfs:label "autoimmune disorder of gastrointestinal tract" ;
rdfs:comment "A hypersensitivity reaction type II disease that involves the alimentary part of gastrointestinal system." ;
rdfs:subClassOf obo:MONDO_0004335 , obo:MONDO_0007179 .
obo:HP_5200330 a rdfs:Class ;
rdfs:label "Suicide behaviors" ;
rdfs:comment "Suicide attempts or preparations" ;
rdfs:subClassOf obo:HP_0100716 .
obo:MONDO_0016264 a rdfs:Class ;
rdfs:label "autoimmune hepatitis" ;
rdfs:comment "Hepatitis caused by autoantibodies. Drugs, infections, and toxins may trigger the production of the autoantibodies against the liver parenchyma." ;
rdfs:subClassOf obo:MONDO_0000569 , obo:MONDO_0000586 , obo:MONDO_0000588 , obo:MONDO_0002251 .
obo:MONDO_0002679 a rdfs:Class ;
rdfs:label "cerebral infarction" ;
rdfs:comment "An ischemic condition of the brain, producing a persistent focal neurological deficit in the area of distribution of the cerebral arteries." ;
rdfs:subClassOf obo:MONDO_0005394 , obo:MONDO_1060198 .
obo:MONDO_0004681 a rdfs:Class ;
rdfs:label "learning disability" ;
rdfs:comment "A group of disorders that affect a person's ability to learn or process specific types of information which is in contrast to his/her apparent level of intellect." ;
rdfs:subClassOf obo:MONDO_0000592 .
obo:ECTO_0000524 a rdfs:Class ;
rdfs:label "exposure to mycotoxin" ;
rdfs:comment "An exposure to mycotoxin." ;
rdfs:subClassOf obo:ECTO_0000537 .
obo:MONDO_0020246 a rdfs:Class ;
rdfs:label "inherited vitreoretinopathy" ;
rdfs:subClassOf obo:MONDO_0005283 , obo:MONDO_0100545 .
obo:ECTO_9002126 a rdfs:Class ;
rdfs:label "exposure to environmental food contaminant" ;
rdfs:comment "An exposure to environmental food contaminant." ;
rdfs:subClassOf obo:ECTO_0000931 , obo:ECTO_9002063 .
obo:MONDO_0002406 a rdfs:Class ;
rdfs:label "dermatitis" ;
rdfs:comment "An inflammatory process affecting the skin. Signs include red rash, itching, and blister formation. Representative examples are contact dermatitis, atopic dermatitis, and seborrheic dermatitis." ;
rdfs:subClassOf obo:MONDO_0005093 , obo:MONDO_0021166 .
obo:ECTO_0300002 a rdfs:Class ;
rdfs:label "exposure to smoking nicotine via maternal" ;
rdfs:comment "An exposure event involving nicotine smoking behavior via maternal" ;
rdfs:subClassOf obo:ECTO_0100002 .
obo:MONDO_0005398 a rdfs:Class ;
rdfs:label "upper aerodigestive tract neoplasm" ;
rdfs:comment "Soft tissue tumors or cancer arising from the mucosal surfaces of the lip; oral cavity; pharynx; larynx; and cervical esophagus. Other sites included are the nose and paranasal sinuses; salivary glands; thyroid gland and parathyroid glands; and melanoma and non-melanoma skin cancers of the head and neck. (from Holland et al., Cancer Medicine, 4th ed, p1651)" ;
rdfs:subClassOf obo:MONDO_0005070 .
obo:ECTO_2000076 a rdfs:Class ;
rdfs:label "exposure to pregnancy diet intake" ;
rdfs:comment "An exposure to pregnancy diet intake." ;
rdfs:subClassOf obo:ECTO_2000068 .
obo:MONDO_0005044 a rdfs:Class ;
rdfs:label "hypertensive disorder" ;
rdfs:comment "Persistently high systemic arterial blood pressure. Based on multiple readings (blood pressure determination), hypertension is currently defined as when systolic pressure is consistently greater than 140 mm Hg or when diastolic pressure is consistently 90 mm Hg or more." ;
rdfs:subClassOf obo:MONDO_0000473 .
obo:MONDO_0700057 a rdfs:Class ;
rdfs:label "neurological pain disorder" ;
rdfs:comment "A nervous system disorder that has pain as a major feature." ;
rdfs:subClassOf obo:MONDO_0005071 .
obo:MONDO_0005405 a rdfs:Class ;
rdfs:label "childhood onset asthma" ;
rdfs:comment "Asthma that starts in childhood." ;
rdfs:subClassOf obo:MONDO_0004979 .
obo:MONDO_0004928 a rdfs:Class ;
rdfs:label "lymph node disorder" ;
rdfs:comment "Any disorder of the lymph nodes." ;
rdfs:subClassOf obo:MONDO_0005833 .
obo:ECTO_9000906 a rdfs:Class ;
rdfs:label "exposure to phthalate ester" ;
rdfs:comment "An exposure to phthalate ester." ;
rdfs:subClassOf obo:ECTO_0000163 , obo:ECTO_0000371 .
obo:BFO_0000003 a rdfs:Class ;
rdfs:label "occurrent"@en ;
rdfs:comment "An entity that has temporal parts and that happens, unfolds or develops through time."@en ;
rdfs:subClassOf obo:BFO_0000001 .
obo:MONDO_0021635 a rdfs:Class ;
rdfs:label "neurocristopathy" ;
rdfs:comment "That disease that arises from defects in the development of tissues containing cells commonly derived from the embryonic neural crest cell lineage." ;
rdfs:subClassOf obo:MONDO_0021147 .
obo:MONDO_0009061 a rdfs:Class ;
rdfs:label "cystic fibrosis" ;
rdfs:comment "Autosomal recessive disorder caused by pathogenic variants in the CFTR gene (cystic fibrosis transmembrane conductance regulator), which encodes a chloride and bicarbonate channel expressed in epithelial cells, and follow the diagnosis criteria. Diagnosis requires evidence of CFTR dysfunction, defined as a sweat chloride concentration of 60 mmol/L or greater, or identification of two CF-causing CFTR pathogenic variants, or an abnormal nasal potential difference measurement. CF is a progressive, multi-organ disease characterized by chronic obstructive lung disease with recurrent infections, exocrine pancreatic insufficiency, intestinal obstruction (including meconium ileus in neonates), male infertility due to obstructive azoospermia, hepatobiliary complications, and elevated sweat chloride concentrations." ;
rdfs:subClassOf obo:MONDO_0005087 , obo:MONDO_0006025 .
obo:MONDO_0021248 a rdfs:Class ;
rdfs:label "nervous system neoplasm" ;
rdfs:comment "A neoplasm (disease) that involves the nervous system." ;
rdfs:subClassOf obo:MONDO_0005070 , obo:MONDO_0005071 .
obo:HP_0001952 a rdfs:Class ;
rdfs:label "Glucose intolerance" ;
rdfs:comment "Glucose intolerance (GI) can be defined as dysglycemia that comprises both prediabetes and diabetes. It includes the conditions of impaired fasting glucose (IFG) and impaired glucose tolerance (IGT) and diabetes mellitus (DM)." ;
rdfs:subClassOf obo:HP_0011014 .
obo:ECTO_6000007 a rdfs:Class ;
rdfs:label "exposure to substance abuse" ;
rdfs:comment "An exposure event involving Substance Abuse" ;
rdfs:subClassOf obo:ECTO_6000016 .
obo:ECTO_2000123 a rdfs:Class ;
rdfs:label "exposure to multivitamin supplementation" ;
rdfs:comment "An exposure to multivitamin supplementation." ;
rdfs:subClassOf obo:ECTO_2000068 , obo:ECTO_8000000 .
obo:MONDO_0005072 a rdfs:Class ;
rdfs:label "neuroblastoma" ;
rdfs:comment "Neuroblastoma (NB) is the most common solid, extracranial childhood tumor. It is an aggressive pediatric cancer that originates from neural crest tissues of the sympathetic nervous system." ;
rdfs:subClassOf obo:MONDO_0006316 , obo:MONDO_0021635 .
obo:MONDO_0006517 a rdfs:Class ;
rdfs:label "childhood malignant neoplasm" ;
rdfs:comment "A malignant tumor that occurs in children. Representative examples include soft tissue and bone sarcomas (e.g. osteosarcoma) and embryonal neoplasms (e.g. hepatoblastoma and rhabdoid tumor)." ;
rdfs:subClassOf obo:MONDO_0004992 , obo:MONDO_0021079 .
obo:HP_5210000 a rdfs:Class ;
rdfs:label "Unusual bacterial infection" ;
rdfs:comment "Increased susceptibility to bacterial infections as manifested by recurrent or severe/invasive bacterial infection, or by bacterial infection in an unusual anatomical location." ;
rdfs:subClassOf obo:HP_0032101 .
obo:MONDO_0001208 a rdfs:Class ;
rdfs:label "acute respiratory failure" ;
rdfs:comment "Life-threatening respiratory failure that develops rapidly. Causes include injury, sepsis, drug overdose, and pancreatitis. It manifests with dyspnea and cyanosis and may lead to cardiovascular shock." ;
rdfs:subClassOf obo:MONDO_0020683 , obo:MONDO_0021113 .
obo:MONDO_0021681 a rdfs:Class ;
rdfs:label "sexually transmitted disease" ;
rdfs:comment "A Disease due to or propagated by sexual contact." ;
rdfs:subClassOf obo:MONDO_0005039 , obo:MONDO_0005550 .
obo:ECTO_7000069 a rdfs:Class ;
rdfs:label "exposure to organic material" ;
rdfs:comment "A exposure event involving the interaction of an exposure receptor to organic material." ;
rdfs:subClassOf obo:ECTO_0000015 .
obo:MONDO_0021583 a rdfs:Class ;
rdfs:label "melanocytic skin neoplasm" ;
rdfs:comment "A melanocytic neoplasm that involves the zone of skin." ;
rdfs:subClassOf obo:MONDO_0002531 , obo:MONDO_0021143 .
obo:ECTO_6000013 a rdfs:Class ;
rdfs:label "exposure to smoking" ;
rdfs:comment "An exposure event involving Smoking" ;
rdfs:subClassOf obo:ECTO_6000016 .
obo:HP_0030872 a rdfs:Class ;
rdfs:label "Abnormal cardiac ventricular function" ;
rdfs:comment "An abnormality of the cardiac ventricular function." ;
rdfs:subClassOf obo:HP_0011025 .
obo:MONDO_0100575 a rdfs:Class ;
rdfs:label "genetic generalized epilepsy" ;
rdfs:comment "A generalized epilepsy that is understood to have a genetic etiology. This does not always mean that the epilepsy is inherited or can be transmitted to offspring, as the genetic etiology may be a de novo pathogenic variant, or the genetic etiology may have complex/polygenic inheritance." ;
rdfs:subClassOf obo:MONDO_0100574 .
obo:IAO_8000015 a rdfs:Class ;
rdfs:label "template generated ontology module"@en ;
rdfs:comment "An ontology module that is automatically generated from a template specification and fillers for slots in that template."@en ;
rdfs:seeAlso , , ;
rdfs:subClassOf obo:IAO_8000014 .
obo:MONDO_0004750 a rdfs:Class ;
rdfs:label "language disorder" ;
rdfs:comment "A category of disorders characterized by an impairment in the development of an individual's language capabilities, which is in contrast to his/her non-verbal intellect." ;
rdfs:subClassOf obo:MONDO_0002182 .
obo:MONDO_0005364 a rdfs:Class ;
rdfs:label "Graves disease" ;
rdfs:comment "Graves' disease is an autoimmune disorder that leads to overactivity of the thyroid gland (hyperthyroidism).It is caused by an abnormal immune system response that causes the thyroid gland to produce too much thyroid hormones. Graves disease is the most common cause of hyperthyroidism andoccurs mostoften in women over age 20. However, the disorder may occur at any age and may affect males as well.Treatmentmayinclude radioiodine therapy, antithyroid drugs, and/or thyroid surgery." ;
rdfs:subClassOf obo:MONDO_0001104 , obo:MONDO_0005623 , obo:MONDO_1060200 .
obo:ECTO_0000371 a rdfs:Class ;
rdfs:label "exposure to oxygen molecular entity" ;
rdfs:comment "An exposure to oxygen molecular entity." ;
rdfs:subClassOf obo:ECTO_0000231 .
obo:MONDO_0004382 a rdfs:Class ;
rdfs:label "laryngeal disorder" ;
rdfs:comment "A non-neoplastic or neoplastic disorder that affects the larynx. Representative examples include laryngitis, vocal cord polyp, squamous papilloma, and carcinoma." ;
rdfs:subClassOf obo:MONDO_0004867 .
obo:HP_5200241 a rdfs:Class ;
rdfs:label "Recurrent maladaptive behavior" ;
rdfs:comment "A repeating behavior that is either immediately unproductive or has negative long-term consequences. This includes harmful coping mechanisms such as addictive behavior and failure to control impulses and compulsions." ;
rdfs:subClassOf obo:HP_0000708 .
obo:ECTO_9002558 a rdfs:Class ;
rdfs:label "exposure to polyamine" ;
rdfs:comment "An exposure to polyamine." ;
rdfs:subClassOf obo:ECTO_9000190 .
obo:MONDO_0043905 a rdfs:Class ;
rdfs:label "pneumonitis" ;
rdfs:comment "An inflammatory process affecting the lung parenchyma. It is a milder form of lung inflammation compared to pneumonia." ;
rdfs:subClassOf obo:MONDO_0005275 , obo:MONDO_0021166 .
obo:MONDO_0000693 a rdfs:Class ;
rdfs:label "bipolar II disorder" ;
rdfs:comment "A bipolar disorder that is characterized by at least one hypomanic episode and at least one major depressive episode; with this disorder, depressive episodes are more frequent and more intense than manic episodes." ;
rdfs:subClassOf obo:MONDO_0004985 .
obo:MONDO_0007179 a rdfs:Class ;
rdfs:label "autoimmune disease" ;
rdfs:comment "A disorder resulting from loss of function or tissue destruction of an organ or multiple organs, arising from humoral or cellular immune responses of the individual to their own tissue constituents. It may be systemic (e.g., systemic lupus erythematosus), or organ specific, (e.g., thyroiditis)." ;
rdfs:subClassOf obo:MONDO_0005046 .
obo:MONDO_0019781 a rdfs:Class ;
rdfs:label "astrocytoma (excluding glioblastoma)" ;
rdfs:comment "A tumor of the brain or spinal cord showing astrocytic differentiation. It includes the following clinicopathological entities: pilocytic astrocytoma, diffuse astrocytoma, anaplastic astrocytoma, pleomorphic xanthoastrocytoma, and subependymal giant cell astrocytoma." ;
rdfs:subClassOf obo:MONDO_0021636 .
obo:MONDO_0000429 a rdfs:Class ;
rdfs:label "autosomal genetic disease" ;
rdfs:comment "A monogenic disease that is has material basis in a mutation in a single gene on one of the non-sex chromosomes." ;
rdfs:subClassOf obo:MONDO_0003847 .
obo:MONDO_0007959 a rdfs:Class ;
rdfs:label "medulloblastoma" ;
rdfs:comment "A malignant, invasive embryonal neoplasm arising from the cerebellum. It occurs predominantly in children and has the tendency to metastasize via the cerebrospinal fluid pathways. Signs and symptoms include truncal ataxia, disturbed gait, lethargy, headache, and vomiting. There are four histologic variants: classic medulloblastoma, large cell/anaplastic medulloblastoma, desmoplastic/nodular medulloblastoma, and medulloblastoma with extensive nodularity." ;
rdfs:subClassOf obo:MONDO_0002913 , obo:MONDO_0005564 .
obo:HP_0030828 a rdfs:Class ;
rdfs:label "Wheezing" ;
rdfs:comment "A high-pitched whistling sound associated with labored breathing." ;
rdfs:subClassOf obo:HP_0030829 .
obo:MONDO_0002329 a rdfs:Class ;
rdfs:label "testicular disorder" ;
rdfs:comment "A non-neoplastic or neoplastic disorder affecting the testis. Representative examples include torsion, infarction, germ cell tumor, sex cord-stromal tumor, lymphoma, and leukemia." ;
rdfs:subClassOf obo:MONDO_0002259 , obo:MONDO_0003150 .
obo:HP_0000119 a rdfs:Class ;
rdfs:label "Abnormality of the genitourinary system" ;
rdfs:comment "The presence of any abnormality of the genitourinary system." ;
rdfs:subClassOf obo:HP_0000118 .
obo:MONDO_0005411 a rdfs:Class ;
rdfs:label "gallbladder cancer" ;
rdfs:comment "A malignant neoplasm involving the gall bladder" ;
rdfs:subClassOf obo:MONDO_0002516 , obo:MONDO_0021253 .
obo:MONDO_0002087 a rdfs:Class ;
rdfs:label "peritoneum cancer" ;
rdfs:comment "A malignant neoplasm involving the peritoneum" ;
rdfs:subClassOf obo:MONDO_0004992 , obo:MONDO_0006901 .
obo:MONDO_0024270 a rdfs:Class ;
rdfs:label "parasitic intestinal disorder" ;
rdfs:comment "Infections of the INTESTINES with PARASITES, commonly involving PARASITIC WORMS. Infections with roundworms (NEMATODE INFECTIONS) and tapeworms (CESTODE INFECTIONS) are also known as HELMINTHIASIS." ;
rdfs:subClassOf obo:MONDO_0005020 , obo:MONDO_0005135 , obo:MONDO_0043424 .
obo:MONDO_0002267 a rdfs:Class ;
rdfs:label "obstructive lung disease" ;
rdfs:comment "Any disorder marked by obstruction of conducting airways of the lung. airway obstruction may be acute, chronic, intermittent, or persistent." ;
rdfs:subClassOf obo:MONDO_0005275 .
obo:MONDO_0019632 a rdfs:Class ;
rdfs:label "Lyme disease" ;
rdfs:comment "Lyme disease (named after the towns in the USA where the disease was first identified) is a bacterial infection caused by Borrelia burgdorferi." ;
rdfs:subClassOf obo:MONDO_0000314 , obo:MONDO_0021839 , obo:MONDO_0025294 .
obo:MONDO_0006485 a rdfs:Class ;
rdfs:label "uterine carcinosarcoma" ;
rdfs:comment "A usually aggressive malignant neoplasm arising from the uterine corpus and less often the cervix. It is characterized by the presence of two components: a malignant epithelial component and a sarcomatous component. In the uterine corpus the epithelial component is usually glandular whereas in the cervix is usually non-glandular. Carcinosarcoma of the cervix, although it is aggressive, it may have a better prognosis compared to the uterine corpus carcinosarcoma." ;
rdfs:subClassOf obo:MONDO_0002715 , obo:MONDO_0002928 .
obo:ECTO_9002063 a rdfs:Class ;
rdfs:label "exposure to food component" ;
rdfs:comment "An exposure to food component." ;
rdfs:subClassOf obo:ECTO_0000485 .
obo:MONDO_0004982 a rdfs:Class ;
rdfs:label "pancreatitis" ;
rdfs:comment "Inflammation of the pancreas." ;
rdfs:subClassOf obo:MONDO_0002356 , obo:MONDO_0021166 .
obo:MONDO_0006474 a rdfs:Class ;
rdfs:label "transitional cell carcinoma" ;
rdfs:comment "A malignant neoplasm arising from the transitional epithelium, usually affecting the urinary bladder, ureter, or renal pelvis. It may or may not have a papillary configuration. It is graded 1 to 3 or 4 according to the degree of cellular differentiation and architectural patterns. Grade 1 transitional cell carcinoma is histologically benign but it may recur. Transitional cell carcinomas may also affect the upper respiratory tract and the ovaries." ;
rdfs:subClassOf obo:MONDO_0004993 .
obo:MONDO_0002232 a rdfs:Class ;
rdfs:label "nasal cavity disorder" ;
rdfs:comment "A disease involving the nasal cavity." ;
rdfs:subClassOf obo:MONDO_0002436 , obo:MONDO_0004867 .
obo:MONDO_0002051 a rdfs:Class ;
rdfs:label "integumentary system disorder" ;
rdfs:comment "A disease involving the integumental system." ;
rdfs:subClassOf obo:MONDO_7770006 .
obo:MONDO_0016642 a rdfs:Class ;
rdfs:label "meningioma" ;
rdfs:comment "A generally slow growing tumor attached to the dura mater. It is composed of neoplastic meningothelial (arachnoidal) cells. It typically occurs in adults, often women and it has a wide range of histopathological appearances. Of the various subtypes, meningothelial, fibrous and transitional meningiomas are the most common. Most meningiomas are WHO grade I tumors, and some are WHO grade II or III tumors. Most subtypes share a common clinical behavior, although some subtypes are more likely to recur and follow a more aggressive clinical course. (Adapted from WHO)" ;
rdfs:subClassOf obo:MONDO_0016743 .
obo:MONDO_0007243 a rdfs:Class ;
rdfs:label "Burkitt lymphoma" ;
rdfs:comment "A rare form of malignant mature B-cell non-Hodgkin lymphoma." ;
rdfs:subClassOf obo:MONDO_0003847 , obo:MONDO_0004949 , obo:MONDO_0017343 , obo:MONDO_0017595 .
obo:ECTO_3000001 a rdfs:Class ;
rdfs:label "exposure to virus" ;
rdfs:comment "A history of exposure to Viruses." ;
rdfs:subClassOf obo:ECTO_3000000 .
obo:HP_0012337 a rdfs:Class ;
rdfs:label "Abnormal homeostasis" ;
rdfs:comment "An anomaly in the processes involved in the maintenance of an internal equilibrium." ;
rdfs:subClassOf obo:HP_0001939 .
obo:MONDO_0023113 a rdfs:Class ;
rdfs:label "familial colorectal cancer" ;
rdfs:comment "Familial colon cancer is a cluster of colon cancer within a family. Most cases of colon cancer occur sporadically in people with little to no family history of the condition. Approximately 3-5% of colon cancer is considered 'hereditary' and is thought to be caused by an inherited predisposition tocolon cancer that is passed down through a family in an autosomal dominant or autosomal recessive manner. In some of these families, the underlying genetic cause is not known; however, many of these cases are caused by changes (mutations) in the APC , MYH , MLH1 , MSH2 , MSH6 , PMS2 , EPCAM , PTEN , STK11 , SMAD4 , BMPR1A , NTHL1 , POLE , and POLD1 genes (which are associated with hereditary cancer syndromes). An additional 10-30% of people diagnosed with colon cancer have a significant family history of the condition but have no identifiable mutation in a gene known to cause a hereditary predisposition to colon cancer. These clusters of colon cancer are likely due to a combination of gene(s) and other shared factors such as environment and lifestyle. High-risk cancer screening and other preventative measures such as prophylactic surgeries are typically recommended in people who have an increased risk for colon cancer based on their personal and/or family histories." ;
rdfs:subClassOf obo:MONDO_0003847 , obo:MONDO_0005575 .
obo:MONDO_0004959 a rdfs:Class ;
rdfs:label "plasma cell neoplasm" ;
rdfs:comment "A clonal proliferation of immunoglobulin-secreting plasma cells. This category includes plasma cell myeloma, plasma cell leukemia, plasmacytoma, monoclonal immunoglobulin deposition disease, and monoclonal gammopathy of undetermined significance." ;
rdfs:subClassOf obo:MONDO_0004949 .
obo:MONDO_0005129 a rdfs:Class ;
rdfs:label "cataract" ;
rdfs:comment "Partial or complete opacity of the crystalline lens of one or both eyes that decreases visual acuity and eventually results in blindness. Some cataracts appear in infancy or in childhood, but most develop in older individuals. (Sternberg Diagnostic Surgical Pathology, 3rd ed.)" ;
rdfs:subClassOf obo:MONDO_0001176 , obo:MONDO_0003847 .
obo:MONDO_0005335 a rdfs:Class ;
rdfs:label "colorectal neoplasm" ;
rdfs:comment "A benign or malignant neoplasm that affects the colon or rectum. Representative examples of benign neoplasms include lipoma and leiomyoma. Representative examples of malignant neoplasms include carcinoma, lymphoma, and sarcoma. Colorectal adenomas always exhibit epithelial dysplasia and are considered premalignant neoplasms." ;
rdfs:subClassOf obo:MONDO_0021118 , obo:MONDO_0024634 .
obo:MONDO_0002120 a rdfs:Class ;
rdfs:label "neuroendocrine carcinoma" ;
rdfs:comment "A malignant neuroendocrine neoplasm composed of cells containing secretory granules that stain positive for NSE and chromogranin. The neoplastic cells are often round and form clusters or trabecular sheets. Representative examples are small cell carcinoma, large cell neuroendocrine carcinoma, and Merkel cell carcinoma." ;
rdfs:subClassOf obo:MONDO_0004993 , obo:MONDO_0019496 , obo:MONDO_0021069 .
obo:ECTO_3000273 a rdfs:Class ;
rdfs:label "exposure to human gammaherpesvirus 4" ;
rdfs:comment "A history of exposure to human gammaherpesvirus 4." ;
rdfs:subClassOf obo:ECTO_3000001 .
obo:MONDO_0002656 a rdfs:Class ;
rdfs:label "skin carcinoma" ;
rdfs:comment "A carcinoma that arises from epithelial cells of the zone of skin" ;
rdfs:subClassOf obo:MONDO_0002898 , obo:MONDO_0004993 , obo:MONDO_0021634 .
obo:MONDO_0003538 a rdfs:Class ;
rdfs:label "precursor lymphoblastic lymphoma/leukemia" ;
rdfs:comment "A neoplasm of immature malignant lymphocytes (lymphoblasts) committed to the B-cell or T-cell lineage. Neoplasms involving the bone marrow and the peripheral blood are called precursor lymphoblastic leukemias or acute lymphoblastic leukemias. Neoplasms involving primarily lymph nodes or extranodal sites are called lymphoblastic lymphomas. -- 2003" ;
rdfs:subClassOf obo:MONDO_0005157 .
obo:MONDO_0005271 a rdfs:Class ;
rdfs:label "allergic disease" ;
rdfs:comment "An immune response that occurs following re-exposure to an innocuous antigen, and that requires the presence of existing antibodies against that antigen. This response involves the binding of IgE to mast cells, and may worsen with repeated exposures." ;
rdfs:subClassOf obo:MONDO_0000605 .
obo:MONDO_0005561 a rdfs:Class ;
rdfs:label "aortic disorder" ;
rdfs:comment "Pathology involving the thoracic, thoracoabdominal, or abdominal aorta (including aneurysms). (ACC)" ;
rdfs:subClassOf obo:MONDO_0000473 .
obo:MONDO_0005385 a rdfs:Class ;
rdfs:label "vascular disorder" ;
rdfs:comment "A general term used to describe any disease affecting blood vessels]. It includes vascular abnormalities caused by degenerative, metabolic and inflammatory conditions, embolic diseases, coagulative disorders, and functional disorders such as posteri or reversible encephalopathy syndrome." ;
rdfs:subClassOf obo:MONDO_0004995 .
obo:HP_0032180 a rdfs:Class ;
rdfs:label "Abnormal circulating metabolite concentration" ;
rdfs:comment "An abnormal level of an analyte measured in the blood." ;
rdfs:subClassOf obo:HP_0001939 .
obo:MONDO_1060198 a rdfs:Class ;
rdfs:label "ischemic stroke" ;
rdfs:comment "A stroke disorder caused by obstruction of blood flow to the brain, due to thrombotic (local blood clot formation) or embolic (due to a blood clot or other material traveling from another site) event." ;
rdfs:subClassOf obo:MONDO_0005098 .
obo:MONDO_0005141 a rdfs:Class ;
rdfs:label "Pseudomonas infection" ;
rdfs:comment "Infections with bacteria of the genus pseudomonas." ;
rdfs:subClassOf obo:MONDO_0005113 .
obo:MONDO_0001854 a rdfs:Class ;
rdfs:label "lacrimal apparatus disorder" ;
rdfs:comment "A non-neoplastic or neoplastic disorder that affects the lacrimal apparatus." ;
rdfs:subClassOf obo:MONDO_0000462 , obo:MONDO_0005328 .
obo:HP_0012373 a rdfs:Class ;
rdfs:label "Abnormal eye physiology" ;
rdfs:comment "A functional anomaly of the eye." ;
rdfs:subClassOf obo:HP_0000478 .
obo:MONDO_0002256 a rdfs:Class ;
rdfs:label "cervix disorder" ;
rdfs:comment "A non-neoplastic or neoplastic disorder that affects the cervix. Representative examples include cervicitis, endocervical polyp, and carcinoma." ;
rdfs:subClassOf obo:MONDO_0002654 .
obo:MONDO_0021674 a rdfs:Class ;
rdfs:label "post-viral disorder" ;
rdfs:comment "A post-infectious disorder that follows viral infection but is distinct from the viral infection itself and its usual manifestations." ;
rdfs:subClassOf obo:MONDO_0021669 .
obo:MONDO_0024503 a rdfs:Class ;
rdfs:label "digestive system neuroendocrine neoplasm" ;
rdfs:comment "A neoplasm with neuroendocrine differentiation arising from the digestive system. It includes neuroendocrine tumors (well-differentiated endocrine tumors or carcinoid tumors and well differentiated endocrine carcinomas) and neuroendocrine carcinomas (poorly differentiated neuroendocrine carcinomas, small cell carcinomas, and large cell neuroendocrine carcinomas)." ;
rdfs:subClassOf obo:MONDO_0004335 , obo:MONDO_0019496 , obo:MONDO_0021223 .
obo:MONDO_0858950 a rdfs:Class ;
rdfs:label "traumatic brain injury" ;
rdfs:comment "A brain disease that is characterized by brain dysfunction caused by an outside force, usually a violent blow to the head." ;
rdfs:subClassOf obo:MONDO_0043510 .
obo:MONDO_0024643 a rdfs:Class ;
rdfs:label "myocardial disorder" ;
rdfs:comment "A disorder that affects the muscle tissue of the heart. Representative examples include myocardial infarction, myocarditis, and cardiomyopathy." ;
rdfs:subClassOf obo:MONDO_0005267 .
obo:MONDO_0002515 a rdfs:Class ;
rdfs:label "hepatobiliary disorder" ;
rdfs:comment "A non-neoplastic or neoplastic disorder that affects the liver, bile ducts, and gallbladder. Representative examples of non-neoplastic disorders include hepatitis, cirrhosis, cholangitis, and cholecystitis. Representative examples of neoplastic disorders include hepatocellular adenoma, hepatocellular carcinoma, and cholangiocarcinoma." ;
rdfs:subClassOf obo:MONDO_0004335 .
obo:MONDO_0004948 a rdfs:Class ;
rdfs:label "B-cell chronic lymphocytic leukemia" ;
rdfs:comment "B-cell chronic lymphocytic leukemia (B-CLL) is a type of B-cell non-Hodgkin lymphoma, and the most common form of leukemia in Western countries, affecting elderly adults (mean age of 67 and 72 years) with a slight male predominance (1.7:1), and characterized by a highly variable clinical presentation that can include asymptomatic disease or non-specific B-symptoms such as unintentional weight loss, severe fatigue, fever (without evidence of infection), and night sweats as well as cervical lymphadenopathy, splenomegaly and frequent infections. Some patients can also develop autoimmune complications such as autoimmune hemolytic anemia or immune thrombocytopenia. The clinical course is extremely heterogeneous with survival ranging from a few months to several decades." ;
rdfs:subClassOf obo:MONDO_0001014 , obo:MONDO_0004949 , obo:MONDO_0004967 , obo:MONDO_0017594 .
obo:HP_0002665 a rdfs:Class ;
rdfs:label "Lymphoma" ;
rdfs:comment "A cancer originating in lymphocytes and presenting as a solid tumor of lymhpoid cells." ;
rdfs:subClassOf obo:HP_0004377 .
obo:MONDO_0012511 a rdfs:Class ;
rdfs:label "preterm premature rupture of the membranes" ;
rdfs:comment "A female reproductive system disease characterized by rupture of chorioamniotic membranes before 37 weeks of gestation." ;
rdfs:subClassOf obo:MONDO_0002263 , obo:MONDO_0003847 .
obo:HP_5210014 a rdfs:Class ;
rdfs:label "Severe Streptococcus pyogenes infection" ;
rdfs:comment "Increased susceptibility to Streptococcus pyogenes infections as manifested by a severe or invasive infection with Streptococcus pyogenes." ;
rdfs:subClassOf obo:HP_5210013 .
obo:MONDO_0005093 a rdfs:Class ;
rdfs:label "skin disorder" ;
rdfs:comment "Any deviation from the normal structure or function of the skin or subcutaneous tissue that is manifested by a characteristic set of symptoms and signs." ;
rdfs:subClassOf obo:MONDO_0002051 .
obo:MONDO_0044334 a rdfs:Class ;
rdfs:label "connective and soft tissue neoplasm" ;
rdfs:comment "A benign, intermediate, or malignant neoplasm that affects the connective and soft tissue." ;
rdfs:subClassOf obo:MONDO_0005070 .
obo:MONDO_0006116 a rdfs:Class ;
rdfs:label "breast carcinoma by gene expression profile" ;
rdfs:comment "A header term that includes the following breast carcinoma subtypes determined by gene expression profiling: luminal A breast carcinoma, luminal B breast carcinoma, HER2 positive breast carcinoma, basal-like breast carcinoma, triple-negative breast carcinoma, and normal breast-like subtype of breast carcinoma." ;
rdfs:subClassOf obo:MONDO_0004989 .
obo:MONDO_0002037 a rdfs:Class ;
rdfs:label "pleural disorder" ;
rdfs:comment "A non-neoplastic or neoplastic disorder that affects the pleura. Representative examples include pleural infection, pleural mesothelioma, and pleural solitary fibrous tumor." ;
rdfs:subClassOf obo:MONDO_0000270 .
obo:MONDO_0020049 a rdfs:Class ;
rdfs:label "autosomal anomaly" ;
rdfs:comment "Chromosomal disorder in which the chromosomal anomaly involves an autosome." ;
rdfs:subClassOf obo:MONDO_0019040 .
obo:ECTO_9001535 a rdfs:Class ;
rdfs:label "exposure to organochlorine pesticide" ;
rdfs:comment "An exposure to organochlorine pesticide." ;
rdfs:subClassOf obo:ECTO_0001152 .
obo:MONDO_0005240 a rdfs:Class ;
rdfs:label "kidney disorder" ;
rdfs:comment "A disease involving the kidney." ;
rdfs:subClassOf obo:MONDO_0002118 .
obo:MONDO_0005517 a rdfs:Class ;
rdfs:label "pharynx cancer" ;
rdfs:comment "A primary or metastatic malignant neoplasm that affects the pharynx." ;
rdfs:subClassOf obo:MONDO_0000376 , obo:MONDO_0002516 , obo:MONDO_0020592 , obo:MONDO_0021246 , obo:MONDO_0021310 .
obo:ECTO_9002382 a rdfs:Class ;
rdfs:label "exposure to metabolite" ;
rdfs:comment "An exposure to metabolite." ;
rdfs:subClassOf obo:ECTO_0000485 .
obo:ECTO_2000079 a rdfs:Class ;
rdfs:label "exposure to radiation therapy" ;
rdfs:comment "An exposure to radiation therapy." ;
rdfs:subClassOf obo:ECTO_2000000 .
obo:MONDO_0000723 a rdfs:Class ;
rdfs:label "stutter disorder" ;
rdfs:comment "A speech disorder characterized by frequent sound or syllable repetitions, sound prolongations, or other dysfluencies that are inappropriate for the individual's age." ;
rdfs:subClassOf obo:MONDO_0004730 , obo:MONDO_0004750 , obo:MONDO_0100545 .
obo:MONDO_0002025 a rdfs:Class ;
rdfs:label "psychiatric disorder" ;
rdfs:comment "A disorder characterized by behavioral and/or psychological abnormalities, often accompanied by physical symptoms. The symptoms may cause clinically significant distress or impairment in social and occupational areas of functioning. Representative examples include anxiety disorders, cognitive disorders, mood disorders and schizophrenia." ;
rdfs:subClassOf obo:MONDO_7770007 .
obo:HP_0012727 a rdfs:Class ;
rdfs:label "Thoracic aortic aneurysm" ;
rdfs:comment "An abnormal localized widening (dilatation) of the thoracic aorta." ;
rdfs:subClassOf obo:HP_0004942 .
obo:ECTO_2000000 a rdfs:Class ;
rdfs:label "exposure to medical action" ;
rdfs:comment "An exposure to medical action." ;
rdfs:subClassOf obo:ExO_0000002 .
obo:MONDO_0037255 a rdfs:Class ;
rdfs:label "ovarian serous tumor" ;
rdfs:comment "A benign, borderline, or malignant epithelial tumor of the ovary characterized by the presence of neoplastic epithelial cells that, in well differentiated tumors, resemble the epithelial cells of the fallopian tube and, in poorly differentiated tumors, show anaplastic features. Approximately thirty to fifty percent of the tumors are bilateral. Grossly, the better differentiated tumors consist of cystic masses, usually unilocular, containing a clear but sometimes viscous fluid. Papillary formations are often present. The more malignant tumors tend to be solid and invasive, with areas of necrosis and hemorrhage." ;
rdfs:subClassOf obo:MONDO_0002229 , obo:MONDO_0037256 .
obo:MONDO_0005130 a rdfs:Class ;
rdfs:label "celiac disease" ;
rdfs:comment "An autoimmune genetic disorder with an unknown pattern of inheritance that primarily affects the digestive tract. It is caused by intolerance to dietary gluten. Consumption of gluten protein triggers an immune response which damages small intestinal villi and prevents adequate absorption of nutrients. Clinical signs include abdominal cramping, diarrhea or constipation and weight loss. If untreated, the clinical course may progress to malnutrition, anemia, osteoporosis and an increased risk of intestinal malignancies. However, the prognosis is favorable with successful avoidance of gluten in the diet." ;
rdfs:subClassOf obo:MONDO_0000588 , obo:MONDO_0003847 , obo:MONDO_0020598 , obo:MONDO_0024635 .
obo:ECTO_9002155 a rdfs:Class ;
rdfs:label "exposure to chlorobiphenyl" ;
rdfs:comment "An exposure to chlorobiphenyl." ;
rdfs:subClassOf obo:ECTO_0001152 , obo:ECTO_9000056 .
obo:HP_0001438 a rdfs:Class ;
rdfs:label "Abnormal abdomen morphology" ;
rdfs:comment "A structural abnormality of the abdomen ('belly'), that is, the part of the body between the pelvis and the thorax." ;
rdfs:subClassOf obo:HP_0025031 .
obo:MONDO_0021679 a rdfs:Class ;
rdfs:label "gram-positive bacterial infections" ;
rdfs:comment "Infections caused by bacteria that retain the crystal violet stain (positive) when treated by the gram-staining method." ;
rdfs:subClassOf obo:MONDO_0005113 .
obo:MONDO_0004608 a rdfs:Class ;
rdfs:label "oropharynx cancer" ;
rdfs:comment "A primary or metastatic malignant neoplasm that affects the oropharynx." ;
rdfs:subClassOf obo:MONDO_0005517 , obo:MONDO_0021364 .
obo:MONDO_0016037 a rdfs:Class ;
rdfs:label "superficial Fibromatosis" ;
rdfs:comment "A poorly circumscribed, intermediate fibrocytic neoplasm arising from the superficial soft tissues. It is characterized by the presence of spindle-shaped fibroblasts, and an infiltrative growth pattern." ;
rdfs:subClassOf obo:MONDO_0005031 .
obo:MONDO_0006496 a rdfs:Class ;
rdfs:label "palsy" ;
rdfs:comment "A general term most often used to describe severe or complete loss of muscle strength due to motor system disease from the level of the cerebral cortex to the muscle fiber. This term may also occasionally refer to a loss of sensory function. (From Adams et al., Principles of Neurology, 6th ed, p45)" ;
rdfs:subClassOf obo:MONDO_0002602 .
obo:MONDO_0002492 a rdfs:Class ;
rdfs:label "acute kidney injury" ;
rdfs:comment "Sudden and sustained deterioration of the kidney function characterized by decreased glomerular filtration rate, increased serum creatinine or oliguria." ;
rdfs:subClassOf obo:MONDO_0001106 , obo:MONDO_0020683 .
obo:MONDO_0000940 a rdfs:Class ;
rdfs:label "trypanosomiasis" ;
rdfs:comment "Infection with protozoa of the genus trypanosoma." ;
rdfs:subClassOf obo:MONDO_0002428 .
obo:MONDO_0005347 a rdfs:Class ;
rdfs:label "hypertriglyceridemia" ;
rdfs:comment "A laboratory test result indicating elevated triglyceride concentration in the blood." ;
rdfs:subClassOf obo:MONDO_0005066 .
obo:MONDO_0011385 a rdfs:Class ;
rdfs:label "intervertebral disk degenerative disorder" ;
rdfs:comment "Any disease of a degenerative nature that affects the intervertebral disk." ;
rdfs:subClassOf obo:MONDO_0000812 , obo:MONDO_0003847 .
obo:MONDO_0005550 a rdfs:Class ;
rdfs:label "infectious disease" ;
rdfs:comment "A disorder directly resulting from the presence and activity of a microbial, viral, or parasitic agent in humans. It can be transmitted by direct or indirect contact." ;
rdfs:subClassOf obo:MONDO_7770010 .
obo:MONDO_0005052 a rdfs:Class ;
rdfs:label "irritable bowel syndrome" ;
rdfs:comment "Irritable bowel syndrome (IBS) is a chronic functional condition of the lower gastrointestinal (GI) tract characterized by abdominal pain or discomfort and disordered bowel habit (diarrhea, constipation, or fluctuation between the two)." ;
rdfs:subClassOf obo:MONDO_0002254 , obo:MONDO_0005020 .
obo:MONDO_0000764 a rdfs:Class ;
rdfs:label "epithelial-stromal TGFBI dystrophy" ;
rdfs:comment "Any corneal dystrophy (disease) in which the cause of the disease is a mutation in the TGFBI gene." ;
rdfs:subClassOf obo:MONDO_0003847 , obo:MONDO_0018102 .
obo:MONDO_0002714 a rdfs:Class ;
rdfs:label "central nervous system cancer" ;
rdfs:comment "A malignant neoplasm involving the central nervous system" ;
rdfs:subClassOf obo:MONDO_0005872 , obo:MONDO_0006130 .
obo:IAO_8000020 a rdfs:Class ;
rdfs:label "EL++ ontology module"@en ;
rdfs:subClassOf obo:IAO_8000019 .
obo:MONDO_0007254 a rdfs:Class ;
rdfs:label "breast cancer" ;
rdfs:comment "A primary or metastatic malignant neoplasm involving the breast. The vast majority of cases are carcinomas arising from the breast parenchyma or the nipple. Malignant breast neoplasms occur more frequently in females than in males." ;
rdfs:subClassOf obo:MONDO_0003274 , obo:MONDO_0021100 .
obo:MONDO_0024467 a rdfs:Class ;
rdfs:label "apocrine sweat gland disorder" ;
rdfs:comment "A disease that involves the apocrine sweat gland." ;
rdfs:subClassOf obo:MONDO_0006615 .
obo:MONDO_0024885 a rdfs:Class ;
rdfs:label "malignant ovarian serous tumor" ;
rdfs:comment "An invasive malignant neoplasm that arises from the ovary and is characterized by the presence of malignant epithelial cells that, in well differentiated tumors, resemble the epithelium of the fallopian tube or, in poorly differentiated tumors, show anaplastic features and marked nuclear atypia. It includes serous adenocarcinoma and serous adenocarcinofibroma." ;
rdfs:subClassOf obo:MONDO_0018364 , obo:MONDO_0037255 .
obo:MONDO_0005487 a rdfs:Class ;
rdfs:label "schizoaffective disorder" ;
rdfs:comment "A disorder in which the individual suffers from both symptoms that qualify as schizophrenia and symptoms that qualify as a mood disorder (e.g., depression or bipolar disorder) for a substantial portion (but not all) of the active period of the illness; for the remainder of the active period of the illness, the individual suffers from delusions or hallucinations in the absence of prominent mood symptoms." ;
rdfs:subClassOf obo:MONDO_0005485 .
obo:ECTO_7000059 a rdfs:Class ;
rdfs:label "exposure to smoke" ;
rdfs:comment "A exposure event involving the interaction of an exposure receptor to smoke." ;
rdfs:subClassOf obo:ECTO_7000114 .
obo:ECTO_9000265 a rdfs:Class ;
rdfs:label "exposure to cocaine" ;
rdfs:comment "An exposure to cocaine." ;
rdfs:subClassOf obo:ECTO_0000163 , obo:ECTO_0000371 , obo:ECTO_9000271 .
obo:MONDO_0005178 a rdfs:Class ;
rdfs:label "osteoarthritis" ;
rdfs:comment "A noninflammatory degenerative joint disease occurring chiefly in older persons, characterized by degeneration of the articular cartilage, hypertrophy of bone at the margins and changes in the synovial membrane. It is accompanied by pain and stiffness, particularly after prolonged activity." ;
rdfs:subClassOf obo:MONDO_0005578 .
obo:MONDO_0005503 a rdfs:Class ;
rdfs:label "developmental disorder of mental health" ;
rdfs:comment "A disease of mental health that occur during a child's developmental period between birth and age 18 resulting in retarding of the child's psychological or physical development." ;
rdfs:subClassOf obo:MONDO_0005084 .
obo:MONDO_0005899 a rdfs:Class ;
rdfs:label "parotid disorder" ;
rdfs:comment "A disease involving the parotid gland." ;
rdfs:subClassOf obo:MONDO_0001142 .
obo:IAO_8000008 a rdfs:Class ;
rdfs:label "analysis subset ontology module"@en ;
rdfs:comment "An ontology module that is intended for usage in analysis or discovery applications."@en ;
rdfs:subClassOf obo:IAO_8000006 .
obo:ECTO_6000041 a rdfs:Class ;
rdfs:label "exposure to Tobacco Use" ;
rdfs:comment "An exposure event involving Tobacco Use" ;
rdfs:subClassOf obo:ECTO_6000016 .
obo:HP_0001298 a rdfs:Class ;
rdfs:label "Encephalopathy" ;
rdfs:comment "Encephalopathy is a term that means brain disease, damage, or malfunction. In general, encephalopathy is manifested by an altered mental state." ;
rdfs:subClassOf obo:HP_0012638 .
obo:MONDO_0021117 a rdfs:Class ;
rdfs:label "lung neoplasm" ;
rdfs:comment "A benign or malignant, primary or metastatic neoplasm involving the lungs. Representative examples of benign neoplasms include adenoma, papilloma, chondroma, and endobronchial lipoma. Representative examples of malignant neoplasms include carcinoma, carcinoid tumor, sarcoma, and lymphoma." ;
rdfs:subClassOf obo:MONDO_0005275 , obo:MONDO_0020641 , obo:MONDO_0021350 .
obo:ECTO_9001695 a rdfs:Class ;
rdfs:label "exposure to nutrient" ;
rdfs:comment "An exposure to nutrient." ;
rdfs:subClassOf obo:ECTO_9002063 .
obo:MONDO_0000402 a rdfs:Class ;
rdfs:label "small cell carcinoma" ;
rdfs:comment "A neuroendocrine carcinoma composed of small malignant cells which are often said to resemble \"oat cells\" under the microscope. Small cell carcinoma most often affects the lungs. Clinically, this is often a rapidly growing cancer that spreads to distant sites early." ;
rdfs:subClassOf obo:MONDO_0002120 .
obo:MONDO_0015474 a rdfs:Class ;
rdfs:label "cryptosporidiosis" ;
rdfs:comment "Intestinal infection with organisms of the genus Cryptosporidium. It occurs in both animals and humans. Symptoms include severe diarrhea." ;
rdfs:subClassOf obo:MONDO_0005707 , obo:MONDO_0024270 .
obo:MONDO_0015597 a rdfs:Class ;
rdfs:label "palmoplantar pustulosis" ;
rdfs:comment "A rare skin disease characterized by chronic eruption of sterile pustules on an erythematous and desquamative background, affecting the palms and soles, sometimes also the lateral aspects of hands and feet. The lesions are usually painful. Nail lesions (such as nail pitting, onycholysis, subungual pustules, and nail dystrophy) are also observed. The condition takes a chronic and relapsing course. Typical associations are psoriatic arthritis, thyroid gland dysfunction, and smoking." ;
rdfs:subClassOf obo:MONDO_0019268 , obo:MONDO_0022205 .
obo:ECTO_2000073 a rdfs:Class ;
rdfs:label "exposure to high fat diet intake" ;
rdfs:comment "An exposure to high fat diet intake." ;
rdfs:subClassOf obo:ECTO_2000068 .
a rdfs:Class ;
rdfs:comment "An unconstrained type or object" .
obo:ECTO_8000036 a rdfs:Class ;
rdfs:label "exposure to air pollution" ;
rdfs:comment "A exposure event involving the interaction of an exposure receptor to air pollution." ;
rdfs:subClassOf obo:ECTO_8000019 .
obo:HP_0025169 a rdfs:Class ;
rdfs:label "Left ventricular systolic dysfunction" ;
rdfs:comment "Abnormality of left ventricular contraction, often defined operationally as an ejection fraction of less than 40 percent." ;
rdfs:subClassOf obo:HP_0005162 .
obo:HP_0001646 a rdfs:Class ;
rdfs:label "Abnormal aortic valve morphology" ;
rdfs:comment "Any abnormality of the aortic valve." ;
rdfs:subClassOf obo:HP_0001654 .
obo:MONDO_0000771 a rdfs:Class ;
rdfs:label "allergic respiratory disease" ;
rdfs:comment "A respiratory system disease with a basis in a pathological type I hypersensitivity reaction." ;
rdfs:subClassOf obo:MONDO_0005087 , obo:MONDO_0005271 .
obo:ECTO_9000097 a rdfs:Class ;
rdfs:label "exposure to radon" ;
rdfs:comment "An exposure to radon molecular entity." ;
rdfs:subClassOf obo:ECTO_0000231 .
obo:MONDO_0019050 a rdfs:Class ;
rdfs:label "inherited hemoglobinopathy" ;
rdfs:comment "An inherited disorder characterized by structural alterations of a globin chain within the hemoglobin molecule." ;
rdfs:subClassOf obo:MONDO_0003847 , obo:MONDO_0044348 .
obo:MONDO_0021163 a rdfs:Class ;
rdfs:label "kidney neoplasm" ;
rdfs:comment "A benign or malignant neoplasm affecting the kidney. Representative examples of benign renal neoplasms include fibroma, lipoma, oncocytoma, and juxtaglomerular cell tumor. Representative examples of malignant renal neoplasms include renal cell carcinoma, renal pelvis carcinoma, Wilms tumor, rhabdoid tumor, sarcoma, and lymphoma." ;
rdfs:subClassOf obo:MONDO_0005240 , obo:MONDO_0021066 .
obo:ECTO_8000044 a rdfs:Class ;
rdfs:label "exposure to sound radiation" ;
rdfs:comment "A exposure event involving the interaction of an exposure receptor to acoustic radiation." ;
rdfs:subClassOf obo:ECTO_0000001 .
obo:MONDO_0005184 a rdfs:Class ;
rdfs:label "pancreatic ductal adenocarcinoma" ;
rdfs:comment "An infiltrating adenocarcinoma that arises from the epithelial cells of the pancreas. It affects males more often than females and the patients are usually over 50 years of age. Microscopically it is characterized by the presence of glandular (ductal) differentiation and desmoplastic stroma formation. Signs and symptoms include pain, loss of weight, and jaundice. It grows rapidly and is usually detected after it has metastasized to other anatomic sites. The prognosis is usually poor." ;
rdfs:subClassOf obo:MONDO_0005606 , obo:MONDO_0006047 .
obo:MONDO_0024575 a rdfs:Class ;
rdfs:label "pregnancy disorder" ;
rdfs:comment "A disorder that is related to pregnancy. Representative examples include ectopic pregnancy, toxemia of pregnancy, and gestational trophoblastic tumor." ;
rdfs:subClassOf obo:MONDO_0700003 .
obo:HP_5210009 a rdfs:Class ;
rdfs:label "Unusual Streptococcus infection" ;
rdfs:comment "Increased susceptibility to Streptococcus infections as manifested by recurrent or severe/invasive infection with Streptococcus, or by Streptococcus infection occurring in an unusual anatomical location." ;
rdfs:subClassOf obo:HP_5210001 .
obo:MONDO_0015140 a rdfs:Class ;
rdfs:label "early-onset autosomal dominant Alzheimer disease" ;
rdfs:comment "A progressive dementia with reduction of cognitive functions. It presents the same phenotype as sporadic Alzheimer disease (AD) but has an early age of onset, usually before 60 years old." ;
rdfs:subClassOf obo:MONDO_0000426 , obo:MONDO_0100087 .
obo:HP_0001626 a rdfs:Class ;
rdfs:label "Abnormality of the cardiovascular system" ;
rdfs:comment "Any abnormality of the cardiovascular system." ;
rdfs:subClassOf obo:HP_0000118 .
obo:HP_0001197 a rdfs:Class ;
rdfs:label "Abnormality of prenatal development or birth" ;
rdfs:comment "An abnormality of the fetus or the birth of the fetus, excluding structural abnormalities." ;
rdfs:subClassOf obo:HP_0000118 .
obo:MONDO_0004425 a rdfs:Class ;
rdfs:label "hyperthyroidism" ;
rdfs:comment "Overactivity of the thyroid gland resulting in overproduction of thyroid hormone and increased metabolic rate. Causes include diffuse hyperplasia of the thyroid gland (Graves' disease), single nodule in the thyroid gland, and thyroiditis. The symptoms are related to the increased metabolic rate and include weight loss, fatigue, heat intolerance, excessive sweating, diarrhea, tachycardia, insomnia, muscle weakness, and tremor." ;
rdfs:subClassOf obo:MONDO_0003240 .
obo:ECTO_0000002 a rdfs:Class ;
rdfs:label "exposure to electromagnetic radiation" ;
rdfs:comment "A exposure event involving the interaction of an exposure receptor to electromagnetic radiation." ;
rdfs:subClassOf obo:ECTO_0000001 .
obo:MONDO_0005041 a rdfs:Class ;
rdfs:label "glaucoma" ;
rdfs:comment "Increased pressure in the eyeball due to obstruction of the outflow of aqueous humor." ;
rdfs:subClassOf obo:MONDO_0005328 .
obo:MONDO_0002715 a rdfs:Class ;
rdfs:label "uterine cancer" ;
rdfs:comment "Primary or metastatic malignant neoplasm involving the uterine corpus and/or the cervix." ;
rdfs:subClassOf obo:MONDO_0001416 , obo:MONDO_0021353 .
obo:ECTO_9002507 a rdfs:Class ;
rdfs:label "exposure to polyunsaturated fatty acid" ;
rdfs:comment "An exposure to polyunsaturated fatty acid." ;
rdfs:subClassOf obo:ECTO_9000308 .
obo:MONDO_0043510 a rdfs:Class ;
rdfs:label "brain injury" ;
rdfs:comment "Acute and chronic (see also brain INJURIES, CHRONIC) injuries to the brain, including the cerebral hemispheres, CEREBELLUM, and brain STEM. Clinical manifestations depend on the nature of injury. Diffuse trauma to the brain is frequently associated with DIFFUSE AXONAL INJURY or COMA, POST-TRAUMATIC. Localized injuries may be associated with NEUROBEHAVIORAL MANIFESTATIONS; HEMIPARESIS, or other focal neurologic deficits." ;
rdfs:subClassOf obo:MONDO_0005560 , obo:MONDO_0044745 .
obo:MONDO_0011184 a rdfs:Class ;
rdfs:label "childhood apraxia of speech" ;
rdfs:subClassOf obo:MONDO_0016226 , obo:MONDO_0100545 .
obo:MONDO_0005105 a rdfs:Class ;
rdfs:label "melanoma" ;
rdfs:comment "A malignant, usually aggressive tumor composed of atypical, neoplastic melanocytes. Most often, melanomas arise in the skin (cutaneous melanomas) and include the following histologic subtypes: superficial spreading melanoma, nodular melanoma, acral lentiginous melanoma, and lentigo maligna melanoma. Cutaneous melanomas may arise from acquired or congenital melanocytic or dysplastic nevi. Melanomas may also arise in other anatomic sites including the gastrointestinal system, eye, urinary tract, and reproductive system. Melanomas frequently metastasize to lymph nodes, liver, lungs, and brain." ;
rdfs:subClassOf obo:MONDO_0021143 .
obo:ECTO_9002364 a rdfs:Class ;
rdfs:label "exposure to terpenoid" ;
rdfs:comment "An exposure to terpenoid." ;
rdfs:subClassOf obo:ECTO_0000200 .
obo:MONDO_0006249 a rdfs:Class ;
rdfs:label "hyperplastic polyp" ;
rdfs:comment "A polyp found mainly in the stomach and colon. Microscopically, it is characterized by elongated, serrated crypts lined by proliferative epithelium. Hyperplastic polyps are traditionally considered non-neoplastic, but ras mutation is common, clonality has been demonstrated and biochemical abnormalities and epidemiological associations that occur in colorectal adenomas and carcinomas have been found (WHO Tumors of the Digestive System, 2000)." ;
rdfs:subClassOf obo:MONDO_0005079 .
obo:MONDO_0002602 a rdfs:Class ;
rdfs:label "central nervous system disorder" ;
rdfs:comment "A disease involving the central nervous system." ;
rdfs:subClassOf obo:MONDO_0005071 .
obo:MONDO_0001014 a rdfs:Class ;
rdfs:label "chronic leukemia" ;
rdfs:comment "A slowly progressing leukemia characterized by a clonal (malignant) proliferation of maturing and mature myeloid cells or mature lymphocytes. When the clonal cellular population is composed of myeloid cells, the process is called chronic myelogenous leukemia. When the clonal cellular population is composed of lymphocytes, it is classified as chronic lymphocytic leukemia, hairy cell leukemia, or T-cell large granular lymphocyte leukemia." ;
rdfs:subClassOf obo:MONDO_0005059 .
obo:HP_0000002 a rdfs:Class ;
rdfs:label "Abnormality of body height" ;
rdfs:comment "Deviation from the norm of height with respect to that which is expected according to age and gender norms." ;
rdfs:subClassOf obo:HP_0001507 .
obo:MONDO_0100038 a rdfs:Class ;
rdfs:label "complex neurodevelopmental disorder" ;
rdfs:comment "A disorder that involves more than one phenotype associated with the central nervous system, including but not limited to intellectual disability, autism, and seizures (epilepsy)." ;
rdfs:subClassOf obo:MONDO_0700092 .
obo:MONDO_1040041 a rdfs:Class ;
rdfs:label "FZD4-related exudative vitreoretinopathy" ;
rdfs:comment "Any exudative vitreoretinopathy caused by a variant in the FZD4 gene." ;
rdfs:subClassOf obo:MONDO_0019516 .
obo:MONDO_0000816 a rdfs:Class ;
rdfs:label "abdominal obesity-metabolic syndrome" ;
rdfs:subClassOf obo:MONDO_0002254 , obo:MONDO_0003916 , obo:MONDO_0019052 .
obo:MONDO_0008040 a rdfs:Class ;
rdfs:label "transient myeloproliferative syndrome" ;
rdfs:comment "A myeloid proliferation occurring in newborns with Down syndrome. It is clinically and morphologically indistinguishable from acute myeloid leukemia and is associated with GATA1 mutations. The blasts display morphologic and immunophenotypic features of megakaryocytic lineage. In the majority of patients the myeloid proliferation undergoes spontaneous remission." ;
rdfs:subClassOf obo:MONDO_0020076 .
obo:MONDO_0045001 a rdfs:Class ;
rdfs:label "cardiac ventricle disorder" ;
rdfs:comment "A disease or disorder that involves the cardiac ventricle." ;
rdfs:subClassOf obo:MONDO_0005267 .
obo:MONDO_0006920 a rdfs:Class ;
rdfs:label "prediabetes syndrome" ;
rdfs:comment "A condition in which blood glucose levels are high, but not high enough to be classified as type 2 diabetes." ;
rdfs:subClassOf obo:MONDO_0002908 .
obo:ECTO_9001124 a rdfs:Class ;
rdfs:label "exposure to fluorine" ;
rdfs:comment "An exposure to fluorine molecular entity." ;
rdfs:subClassOf obo:ECTO_0000231 .
obo:MONDO_0005303 a rdfs:Class ;
rdfs:label "drug dependence" ;
rdfs:comment "Drug dependence - replaced the term \"drug addiction\" and is defined as a state, psychic and sometimes also physical, resulting from the interaction between a living organism and a drug, characterized by behavioral and other responses that always include a compulsion to take the drug on a continuous or periodic basis in order to experience its psychic effects, and sometimes to avoid the discomfort of its absence. Tolerance may or may not be present. A person may be dependent on more than one drug." ;
rdfs:subClassOf obo:MONDO_0004938 .
obo:ECTO_0001571 a rdfs:Class ;
rdfs:label "exposure to mercury" ;
rdfs:comment "An exposure to mercury molecular entity." ;
rdfs:subClassOf obo:ECTO_0000481 .
obo:MONDO_0002429 a rdfs:Class ;
rdfs:label "idiopathic interstitial pneumonia" ;
rdfs:comment "A class of diffuse lung diseases that typically affect the pulmonary interstitium, although some also have a component affecting the airways (for instance, Cryptogenic organizing pneumonitis)." ;
rdfs:subClassOf obo:MONDO_0005249 , obo:MONDO_0700007 .
obo:MONDO_0003582 a rdfs:Class ;
rdfs:label "hereditary breast ovarian cancer syndrome" ;
rdfs:comment "An autosomal dominant inherited syndrome caused by mutations in the BRCA1 or BRCA2 genes. Patients are at high risk of developing breast cancer, particularly before the age of fifty, high risk of developing a second primary breast cancer, and high risk of developing both breast and ovarian cancer." ;
rdfs:subClassOf obo:MONDO_0000426 , obo:MONDO_0015356 .
obo:MONDO_0005004 a rdfs:Class ;
rdfs:label "clear cell adenocarcinoma" ;
rdfs:comment "A malignant neoplasm composed of glandular epithelial clear cells. Various architectural patterns may be seen, including papillary, tubulocystic, and solid." ;
rdfs:subClassOf obo:MONDO_0004970 .
obo:ECTO_0100000 a rdfs:Class ;
rdfs:label "exposure to nicotine addictive consumption" ;
rdfs:comment "An exposure event involving nicotine consumption of an addictive substance" ;
rdfs:subClassOf obo:ExO_0000002 .
obo:MONDO_0016226 a rdfs:Class ;
rdfs:label "specific language disorder" ;
rdfs:subClassOf obo:MONDO_0016225 .
obo:ECTO_0900407 a rdfs:Class ;
rdfs:label "exposure to organonitrogen compound via ingestion" ;
rdfs:comment "An exposure to organonitrogen compound via ingestion route." ;
rdfs:subClassOf obo:ECTO_0900042 , obo:ECTO_9000190 .
obo:HP_0030163 a rdfs:Class ;
rdfs:label "Abnormal vascular physiology" ;
rdfs:comment "Abnormality of vascular function." ;
rdfs:subClassOf obo:HP_0002597 , obo:HP_0011025 .
obo:ECTO_2000068 a rdfs:Class ;
rdfs:label "exposure to dietary intervention" ;
rdfs:comment "An exposure to dietary intervention." ;
rdfs:subClassOf obo:ECTO_2000000 .
obo:IAO_0000027 a rdfs:Class ;
rdfs:label "data entity"@en ;
rdfs:subClassOf obo:IAO_0000030 .
obo:HP_0000745 a rdfs:Class ;
rdfs:label "Abnormal diminished volition" ;
rdfs:comment "A reduction in willful and motivated goal-directed behavior that is considered the determinant of behavior and adaptation that allows individuals to get started, be energized to perform a sustained and directed action." ;
rdfs:subClassOf obo:HP_0025780 .
obo:MONDO_0041656 a rdfs:Class ;
rdfs:label "ST-elevation myocardial infarction" ;
rdfs:comment "A very serious type of heart attack during which one of the heart’s major arteries (one of the arteries that supplies oxygen and nutrient-rich blood to the heart muscle) is blocked. ST-segment elevation is an abnormality detected on the 12-lead ECG." ;
rdfs:subClassOf obo:MONDO_0004781 .
obo:MONDO_0005212 a rdfs:Class ;
rdfs:label "rhabdomyosarcoma" ;
rdfs:comment "A rare aggressive malignant mesenchymal neoplasm arising from skeletal muscle. It usually occurs in children and young adults. Only a small percentage of tumors arise in the skeletal muscle of the extremities. The majority arise in other anatomical sites." ;
rdfs:subClassOf obo:MONDO_0018078 .
obo:MONDO_0100545 a rdfs:Class ;
rdfs:label "hereditary neurological disease" ;
rdfs:comment "A heterogeneous group of genetic conditions with Mendelian (autosomal dominant, recessive, or X-linked) or chromosomal etiology characterized by abnormalities in the brain, spinal cord, nerves, or muscles." ;
rdfs:subClassOf obo:MONDO_0003847 , obo:MONDO_0005071 .
obo:ECTO_9002071 a rdfs:Class ;
rdfs:label "exposure to plasticiser" ;
rdfs:comment "An exposure to plasticiser." ;
rdfs:subClassOf obo:ECTO_0000486 .
obo:ECTO_9000308 a rdfs:Class ;
rdfs:label "exposure to fatty acid" ;
rdfs:comment "An exposure to fatty acid." ;
rdfs:subClassOf obo:ECTO_0000200 , obo:ECTO_0000371 .
obo:MONDO_0005854 a rdfs:Class ;
rdfs:label "mixed connective tissue disease" ;
rdfs:comment "Mixed connective tissue disease (MCTD) is a rare autoimmune disorder that is characterized by features commonly seen in three different connective tissue disorders: systemic lupus erythematosus, scleroderma, and polymyositis. Some affected people may also have symptoms of rheumatoid arthritis. Although MCTD can affect people of all ages, it appears to be most common in women under age 30. Signs and symptoms vary but may include Raynaud's phenomenon ; arthritis; heart, lung and skin abnormalities; kidney disease; muscle weakness, and dysfunction of the esophagus. The cause of MCTD is currently unknown. There is no cure but certain medications such as nonsteroidal anti-inflammatory drugs (NSAIDs), corticosteroids and immunosuppresivedrugsmay help manage the symptoms." ;
rdfs:subClassOf obo:MONDO_0005554 , obo:MONDO_0016663 .
obo:MONDO_0005275 a rdfs:Class ;
rdfs:label "lung disorder" ;
rdfs:comment "A disease involving the lung." ;
rdfs:subClassOf obo:MONDO_0000270 .
obo:MONDO_0020573 a rdfs:Class ;
rdfs:label "inherited disease susceptibility" ;
rdfs:comment "A latent susceptibility to disease at the genetic level, which may be activated under certain conditions." ;
rdfs:subClassOf obo:MONDO_0042489 .
obo:MONDO_0006026 a rdfs:Class ;
rdfs:label "urinary bladder disorder" ;
rdfs:comment "A disease involving the urinary bladder." ;
rdfs:subClassOf obo:MONDO_0002118 .
obo:ECTO_0900029 a rdfs:Class ;
rdfs:label "exposure to vitamin B via ingestion" ;
rdfs:comment "An exposure to B vitamin via ingestion route." ;
rdfs:subClassOf obo:ECTO_0900407 , obo:ECTO_9002026 .
obo:MONDO_0002254 a rdfs:Class ;
rdfs:label "syndromic disease" ;
rdfs:comment "A group of signs, symptoms, and clinicopathological characteristics that may or may not have a genetic basis and collectively define an abnormal condition." ;
rdfs:subClassOf obo:MONDO_7770006 .
obo:MONDO_0021259 a rdfs:Class ;
rdfs:label "prostate neoplasm" ;
rdfs:comment "A neoplasm (disease) that involves the prostate gland." ;
rdfs:subClassOf obo:MONDO_0003105 , obo:MONDO_0006054 .
obo:MONDO_0005264 a rdfs:Class ;
rdfs:label "transient ischemic attack" ;
rdfs:comment "A brief attack (from a few minutes to an hour) of cerebral dysfunction of vascular origin, with no persistent neurological deficit." ;
rdfs:subClassOf obo:MONDO_0005299 , obo:MONDO_1060198 .
obo:ECTO_0070183 a rdfs:Class ;
rdfs:label "exposure to legume food product via ingestion" ;
rdfs:comment "An exposure to legume food product via ingestion." ;
rdfs:subClassOf obo:ECTO_0000015 .
obo:HP_0000924 a rdfs:Class ;
rdfs:label "Abnormality of the skeletal system" ;
rdfs:comment "An abnormality of the skeletal system." ;
rdfs:subClassOf obo:HP_0033127 .
obo:MONDO_0005084 a rdfs:Class ;
rdfs:label "mental disorder" ;
rdfs:comment "A disease that has its basis in the disruption of mental process." ;
rdfs:subClassOf obo:MONDO_0002025 , obo:MONDO_0005560 .
obo:MONDO_0011429 a rdfs:Class ;
rdfs:label "juvenile idiopathic arthritis" ;
rdfs:comment "Juvenile idiopathic arthritis (JIA) is the term used to describe a group of inflammatory articular disorders of unknown cause that begin before the age of 16 and last over 6 weeks. The term juvenile idiopathic arthritis was chosen to signify the absence of any known mechanism underlying the disorder and to highlight the necessity of excluding other types of arthritis occurring in well defined diseases (in particular arthritis occurring in association with infectious, inflammatory and haematooncologic diseases)." ;
rdfs:subClassOf obo:MONDO_0005554 , obo:MONDO_0005578 , obo:MONDO_0700007 .
obo:MONDO_0016749 a rdfs:Class ;
rdfs:label "tumor of cranial and spinal nerves" ;
rdfs:subClassOf obo:MONDO_0021248 .
obo:MONDO_0000270 a rdfs:Class ;
rdfs:label "lower respiratory tract disorder" ;
rdfs:comment "A disease involving the lower respiratory tract." ;
rdfs:subClassOf obo:MONDO_0005087 .
obo:MONDO_0001384 a rdfs:Class ;
rdfs:label "myopia" ;
rdfs:comment "The condition in which the individual does not see far distances clearly." ;
rdfs:subClassOf obo:MONDO_0003847 , obo:MONDO_0004892 , obo:MONDO_0100581 .
obo:MONDO_0024237 a rdfs:Class ;
rdfs:label "inherited neurodegenerative disorder" ;
rdfs:comment "An inherited disorder characterized by progressive degeneration and atrophy of the nervous system." ;
rdfs:subClassOf obo:MONDO_0005559 , obo:MONDO_0100545 .
obo:MONDO_0005191 a rdfs:Class ;
rdfs:label "metastatic melanoma" ;
rdfs:comment "A melanoma that has spread from its primary site to another anatomic site. Melanomas frequently metastasize to lymph nodes, liver, lungs, and brain." ;
rdfs:subClassOf obo:MONDO_0005105 .
obo:HP_0012531 a rdfs:Class ;
rdfs:label "Pain" ;
rdfs:comment "An unpleasant sensory and emotional experience associated with actual or potential tissue damage, or described in terms of such damage." ;
rdfs:subClassOf obo:HP_0025142 .
obo:MONDO_0005554 a rdfs:Class ;
rdfs:label "rheumatic disorder" ;
rdfs:comment "Inflammatory and degenerative diseases of connective tissue structures, such as arthritis." ;
rdfs:subClassOf obo:MONDO_0003900 .
obo:HP_0003107 a rdfs:Class ;
rdfs:label "Abnormal circulating cholesterol concentration" ;
rdfs:comment "Any deviation from the normal concentration of cholesterol in the blood circulation." ;
rdfs:subClassOf obo:HP_0003119 .
obo:MONDO_0015925 a rdfs:Class ;
rdfs:label "interstitial lung disease" ;
rdfs:comment "A diverse group of lung diseases that affect the lung parenchyma. They are characterized by an initial inflammation of pulmonary alveoli that extends to the interstitium and beyond leading to diffuse pulmonary fibrosis. Interstitial lung diseases are classified by their etiology (known or unknown causes), and radiological-pathological features." ;
rdfs:subClassOf obo:MONDO_0005275 .
obo:MONDO_0021118 a rdfs:Class ;
rdfs:label "intestinal neoplasm" ;
rdfs:comment "A benign or malignant neoplasm involving the small or large intestine." ;
rdfs:subClassOf obo:MONDO_0005020 , obo:MONDO_0021223 .
obo:MONDO_0021043 a rdfs:Class ;
rdfs:label "mixed neoplasm" ;
rdfs:comment "A neoplasm composed of at least two distinct cellular populations." ;
rdfs:subClassOf obo:MONDO_0005070 .
obo:MONDO_0005015 a rdfs:Class ;
rdfs:label "diabetes mellitus" ;
rdfs:comment "A metabolic disorder characterized by abnormally high blood sugar levels due to diminished production of insulin or insulin resistance/desensitization." ;
rdfs:subClassOf obo:MONDO_0001933 , obo:MONDO_0002908 .
obo:MONDO_0006294 a rdfs:Class ;
rdfs:label "pleural cancer" ;
rdfs:comment "A primary or metastatic malignant neoplasm affecting the pleura. A representative example of primary malignant pleural neoplasm is the malignant pleural mesothelioma. A representative example of metastatic malignant neoplasm to the pleura is metastatic carcinoma that has spread to the pleura from another anatomic site." ;
rdfs:subClassOf obo:MONDO_0000376 , obo:MONDO_0003274 , obo:MONDO_0021065 .
obo:HP_0004323 a rdfs:Class ;
rdfs:label "Abnormality of body weight" ;
rdfs:comment "An abnormal increase or decrease of weight or an abnormal distribution of mass in the body." ;
rdfs:subClassOf obo:HP_0001507 .
obo:MONDO_0024637 a rdfs:Class ;
rdfs:label "malignant soft tissue neoplasm" ;
rdfs:comment "A malignant neoplasm arising exclusively from the soft tissues." ;
rdfs:subClassOf obo:MONDO_0004992 , obo:MONDO_0006424 .
obo:MONDO_0020665 a rdfs:Class ;
rdfs:label "high grade malignant neoplasm" ;
rdfs:subClassOf obo:MONDO_0004992 .
obo:BFO_0000051 a rdf:Property ;
rdfs:label "has part"@en ;
rdfs:comment "a core relation that holds between a whole and its part"@en ;
rdfs:range xsd:string ;
rdfs:subPropertyOf obo:RO_0002131 .
obo:IAO_0000111 a rdf:Property ;
rdfs:label "editor preferred term"@en ;
rdfs:comment "The concise, meaningful, and human-friendly name for a class or property preferred by the ontology developers. (US-English)"@en ;
rdfs:range xsd:string .
obo:IAO_0000112 a rdf:Property ;
rdfs:label "example of usage" ;
rdfs:comment "A phrase describing how a term should be used and/or a citation to a work which uses it. May also include other kinds of examples that facilitate immediate understanding, such as widely know prototypes or instances of a class, or cases where a relation is said to hold."@en ;
rdfs:range xsd:string .
obo:IAO_0000113 a rdf:Property ;
rdfs:label "in branch"@en ;
rdfs:comment "An annotation property indicating which module the terms belong to. This is currently experimental and not implemented yet."@en ;
rdfs:range xsd:string .
obo:IAO_0000114 a rdf:Property ;
rdfs:label "has curation status"@en ;
rdfs:range xsd:string .
obo:IAO_0000115 a rdf:Property ;
rdfs:label "definition" ;
rdfs:comment "The official definition, explaining the meaning of a class or property. Shall be Aristotelian, formalized and normalized. Can be augmented with colloquial definitions."@en ;
rdfs:range xsd:string .
obo:IAO_0000116 a rdf:Property ;
rdfs:label "editor note"@en ;
rdfs:comment "An administrative note intended for its editor. It may not be included in the publication version of the ontology, so it should contain nothing necessary for end users to understand the ontology."@en ;
rdfs:range xsd:string .
obo:IAO_0000117 a rdf:Property ;
rdfs:label "term editor"@en ;
rdfs:comment "Name of editor entering the term in the file. The term editor is a point of contact for information regarding the term. The term editor may be, but is not always, the author of the definition, which may have been worked upon by several people"@en ;
rdfs:range xsd:string .
obo:IAO_0000118 a rdf:Property ;
rdfs:label "alternative label"@en ;
rdfs:comment "A label for a class or property that can be used to refer to the class or property instead of the preferred rdfs:label. Alternative labels should be used to indicate community- or context-specific labels, abbreviations, shorthand forms and the like."@en ;
rdfs:range xsd:string .
obo:IAO_0000119 a rdf:Property ;
rdfs:label "definition source"@en ;
rdfs:comment "Formal citation, e.g. identifier in external database to indicate / attribute source(s) for the definition. Free text indicate / attribute source(s) for the definition. EXAMPLE: Author Name, URI, MeSH Term C04, PUBMED ID, Wiki uri on 31.01.2007"@en ;
rdfs:range xsd:string .
obo:IAO_0000231 a rdf:Property ;
rdfs:label "has obsolescence reason"@en ;
rdfs:comment "Relates an annotation property to an obsolescence reason. The values of obsolescence reasons come from a list of predefined terms, instances of the class obsolescence reason specification."@en ;
rdfs:range xsd:string .
obo:IAO_0000232 a rdf:Property ;
rdfs:label "curator note"@en ;
rdfs:comment "An administrative note of use for a curator but of no use for a user"@en ;
rdfs:range xsd:string .
obo:IAO_0000233 a rdf:Property ;
rdfs:label "term tracker item"@en ;
rdfs:comment "A URL for a request or discussion of an ontology term."@en ;
rdfs:range xsd:anyURI .
obo:IAO_0000234 a rdf:Property ;
rdfs:label "ontology term requester"@en ;
rdfs:comment "The name of the person, project, or organization that motivated inclusion of an ontology term by requesting its addition."@en ;
rdfs:range xsd:string .
obo:IAO_0000411 a rdf:Property ;
rdfs:label "is denotator type"@en ;
rdfs:comment "Relates an class defined in an ontology, to the type of it's denotator"@en ;
rdfs:range xsd:string .
obo:IAO_0000412 a rdf:Property ;
rdfs:label "imported from"@en ;
rdfs:comment "For external terms/classes, the ontology from which the term was imported"@en ;
rdfs:range xsd:string .
obo:IAO_0000424 a rdf:Property ;
rdfs:label "expand expression to"@en ;
rdfs:comment "A macro expansion tag applied to an object property (or possibly a data property) which can be used by a macro-expansion engine to generate more complex expressions from simpler ones"@en ;
rdfs:range xsd:string .
obo:IAO_0000425 a rdf:Property ;
rdfs:label "expand assertion to"@en ;
rdfs:comment "A macro expansion tag applied to an annotation property which can be expanded into a more detailed axiom."@en ;
rdfs:range xsd:string .
obo:IAO_0000426 a rdf:Property ;
rdfs:label "first order logic expression"@en ;
rdfs:range xsd:string .
obo:IAO_0000427 a rdf:Property ;
rdfs:label "antisymmetric property"@en ;
rdfs:comment "Use boolean value xsd:true to indicate that the property is an antisymmetric property"@en ;
rdfs:range xsd:string ;
rdfs:subPropertyOf obo:OMO_0001001 .
obo:IAO_0000589 a rdf:Property ;
rdfs:label "OBO foundry unique label"@en ;
rdfs:comment "An alternative name for a class or property which is unique across the OBO Foundry."@en ;
rdfs:range xsd:string .
obo:IAO_0000596 a rdf:Property ;
rdfs:label "has ID digit count"@en ;
rdfs:comment "Relates an ontology used to record id policy to the number of digits in the URI. The URI is: the 'has ID prefix\" annotation property value concatenated with an integer in the id range (left padded with \"0\"s to make this many digits)"@en ;
rdfs:range xsd:string .
obo:IAO_0000597 a rdf:Property ;
rdfs:label "has ID range allocated to"@en ;
rdfs:comment "Relates a datatype that encodes a range of integers to the name of the person or organization who can use those ids constructed in that range to define new terms"@en ;
rdfs:range xsd:string .
obo:IAO_0000598 a rdf:Property ;
rdfs:label "has ID policy for"@en ;
rdfs:comment "Relating an ontology used to record id policy to the ontology namespace whose policy it manages"@en ;
rdfs:range xsd:string .
obo:IAO_0000599 a rdf:Property ;
rdfs:label "has ID prefix"@en ;
rdfs:comment "Relates an ontology used to record id policy to a prefix concatenated with an integer in the id range (left padded with \"0\"s to make this many digits) to construct an ID for a term being created."@en ;
rdfs:range xsd:string .
obo:IAO_0000600 a rdf:Property ;
rdfs:label "elucidation"@en ;
rdfs:range xsd:string .
obo:IAO_0000601 a rdf:Property ;
rdfs:label "has associated axiom(nl)"@en ;
rdfs:range xsd:string .
obo:IAO_0000602 a rdf:Property ;
rdfs:label "has associated axiom(fol)"@en ;
rdfs:range xsd:string .
obo:IAO_0000603 a rdf:Property ;
rdfs:label "is allocated id range"@en ;
rdfs:comment "Relates an ontology IRI to an (inclusive) range of IRIs in an OBO name space. The range is give as, e.g. \"IAO_0020000-IAO_0020999\""@en ;
rdfs:range xsd:string .
obo:IAO_0000700 a rdf:Property ;
rdfs:label "has ontology root term"@en ;
rdfs:comment "Ontology annotation property. Relates an ontology to a term that is a designated root term of the ontology. Display tools like OLS can use terms annotated with this property as the starting point for rendering the ontology class hierarchy. There can be more than one root."@en ;
rdfs:range xsd:string .
obo:IAO_0006011 a rdf:Property ;
rdfs:label "may be identical to"@en ;
rdfs:comment "A annotation relationship between two terms in an ontology that may refer to the same (natural) type but where more evidence is required before terms are merged."@en ;
rdfs:range xsd:string .
obo:IAO_0006012 a rdf:Property ;
rdfs:label "scheduled for obsoletion on or after"@en ;
rdfs:comment "Used when the class or object is scheduled for obsoletion/deprecation on or after a particular date."@en ;
rdfs:range xsd:dateTime .
obo:IAO_0010000 a rdf:Property ;
rdfs:label "has axiom label"@en ;
rdfs:range xsd:string .
obo:IAO_0100001 a rdf:Property ;
rdfs:label "term replaced by" ;
rdfs:comment "Use on obsolete terms, relating the term to another term that can be used as a substitute"@en ;
rdfs:range xsd:string .
obo:OMO_0001001 a rdf:Property ;
rdfs:label "logical characteristic of object property" ;
rdfs:comment "This is an annotation used on an object property to indicate a logical characterstic beyond what is possible in OWL." ;
rdfs:range xsd:string .
obo:OMO_0002000 a rdf:Property ;
rdfs:label "defined by construct" ;
rdfs:comment "Links an annotation property to a SPARQL CONSTRUCT query which is meant to provide semantics for a shortcut relation." ;
rdfs:range xsd:string .
obo:OMO_0002001 a rdf:Property ;
rdfs:label "preferred label for community" ;
rdfs:comment "A provenance property that denotes a synonym to be the preferred one for a specific community." ;
rdfs:range xsd:string .
obo:OMO_0003000 a rdf:Property ;
rdfs:label "abbreviation" ;
rdfs:comment "A synonym type for describing abbreviations or initialisms" ;
rdfs:range xsd:string .
obo:OMO_0003001 a rdf:Property ;
rdfs:label "ambiguous synonym" ;
rdfs:comment "A synonym type for describing ambiguous synonyms" ;
rdfs:range xsd:string .
obo:OMO_0003002 a rdf:Property ;
rdfs:label "dubious synonym" ;
rdfs:comment "A synonym type for describing dubious synonyms" ;
rdfs:range xsd:string .
obo:OMO_0003003 a rdf:Property ;
rdfs:label "layperson synonym" ;
rdfs:comment "A synonym type for describing layperson or colloquial synonyms" ;
rdfs:range xsd:string .
obo:OMO_0003004 a rdf:Property ;
rdfs:label "plural form" ;
rdfs:comment "A synonym type for describing pluralization synonyms" ;
rdfs:range xsd:string .
obo:OMO_0003005 a rdf:Property ;
rdfs:label "UK spelling synonym" ;
rdfs:comment "A synonym type for describing UK spelling variants" ;
rdfs:range xsd:string .
obo:OMO_0003006 a rdf:Property ;
rdfs:label "misspelling" ;
rdfs:comment "A synonym type for common misspellings" ;
rdfs:range xsd:string .
obo:OMO_0003007 a rdf:Property ;
rdfs:label "misnomer" ;
rdfs:comment "A synonym type for misnomers, i.e., a synonym that is not technically correct but is commonly used anyway" ;
rdfs:range xsd:string .
obo:OMO_0003008 a rdf:Property ;
rdfs:label "previous name" ;
rdfs:comment "A synonym type for names that have been used as primary labels in the past." ;
rdfs:range xsd:string .
obo:OMO_0003009 a rdf:Property ;
rdfs:label "legal name" ;
rdfs:comment "A synonym type for the legal entity name" ;
rdfs:range xsd:string .
obo:OMO_0003010 a rdf:Property ;
rdfs:label "International Nonproprietary Name" ;
rdfs:comment "The International Nonproprietary Name (INN) is a standardize name for a pharmaceutical drug or active ingredient issued by the World Health Organization (WHO) meant to address the issues with country- or language-specific brand names. These are issued in several languages, including English, Latin, French, Russian, Spanish, Arabic, and Chinese." ;
rdfs:range xsd:string .
obo:OMO_0003011 a rdf:Property ;
rdfs:label "latin term" ;
rdfs:comment "A synonym type for describing Latin term synonyms." ;
rdfs:range xsd:string .
obo:OMO_0003012 a rdf:Property ;
rdfs:label "acronym" ;
rdfs:comment "A synonym type for describing abbreviations that are a part of the full name's words, such as initialisms or alphabetisms." ;
rdfs:range xsd:string .
obo:OMO_0003014 a rdf:Property ;
rdfs:label "has ontology hierarchical property" ;
rdfs:comment "Relates an ontology to predicates/properties that should be used by user interfaces to render the hierarchical structure of the ontology. Typically, this is rdfs:subClassOf, but in ontologies that are partonomies, this might also include BFO:0000050 (part of). Tools like OLS can use predicates annotated with this property for rendering the ontology class hierarchy. There can be more than one hierarchical property. In the absence of any, it should be assumed that it is rdfs:subClassOf." ;
rdfs:range xsd:string .
obo:OMO_0004000 a rdf:Property ;
rdfs:label "has symbol" ;
rdfs:comment "An information content entity that is a mark(s) or character(s) used as a conventional representation of another entity." ;
rdfs:range xsd:string .
obo:RO_0000052 a rdf:Property ;
rdfs:label "characteristic of"@en ;
rdfs:comment "a relation between a specifically dependent continuant (the characteristic) and any other entity (the bearer), in which the characteristic depends on the bearer for its existence."@en ;
rdfs:range xsd:string ;
rdfs:subPropertyOf obo:RO_0002314 .
obo:RO_0000053 a rdf:Property ;
rdfs:label "has characteristic"@en ;
rdfs:comment "Inverse of characteristic_of"@en ;
rdfs:range obo:BFO_0000020 .
obo:RO_0000080 a rdf:Property ;
rdfs:label "quality of"@en ;
rdfs:comment "a relation between a quality and an independent continuant (the bearer), in which the quality specifically depends on the bearer for its existence"@en ;
rdfs:range xsd:string ;
rdfs:subPropertyOf obo:RO_0000052 .
obo:RO_0000081 a rdf:Property ;
rdfs:label "role of"@en ;
rdfs:comment "a relation between a role and an independent continuant (the bearer), in which the role specifically depends on the bearer for its existence"@en ;
rdfs:range xsd:string ;
rdfs:subPropertyOf obo:RO_0000052 .
obo:RO_0000086 a rdf:Property ;
rdfs:label "has quality"@en ;
rdfs:comment "a relation between an independent continuant (the bearer) and a quality, in which the quality specifically depends on the bearer for its existence"@en ;
rdfs:range obo:BFO_0000019 ;
rdfs:subPropertyOf obo:RO_0000053 .
obo:RO_0000092 a rdf:Property ;
rdfs:label "disposition of"@en ;
rdfs:comment "inverse of has disposition" ;
rdfs:range xsd:string ;
rdfs:subPropertyOf obo:RO_0000052 .
obo:RO_0001015 a rdf:Property ;
rdfs:label "location of"@en ;
rdfs:comment "a relation between two independent continuants, the location and the target, in which the target is entirely within the location"@en ;
rdfs:range .
obo:RO_0002013 a rdf:Property ;
rdfs:label "has regulatory component activity" ;
rdfs:comment "A 'has regulatory component activity' B if A and B are GO molecular functions (GO_0003674), A has_component B and A is regulated by B." ;
rdfs:range xsd:string ;
rdfs:subPropertyOf obo:RO_0002334 , obo:RO_0002017 .
obo:RO_0002014 a rdf:Property ;
rdfs:label "has negative regulatory component activity" ;
rdfs:comment "A relationship that holds between a GO molecular function and a component of that molecular function that negatively regulates the activity of the whole. More formally, A 'has regulatory component activity' B iff :A and B are GO molecular functions (GO_0003674), A has_component B and A is negatively regulated by B." ;
rdfs:range xsd:string ;
rdfs:subPropertyOf obo:RO_0002335 , obo:RO_0002013 .
obo:RO_0002015 a rdf:Property ;
rdfs:label "has positive regulatory component activity" ;
rdfs:comment "A relationship that holds between a GO molecular function and a component of that molecular function that positively regulates the activity of the whole. More formally, A 'has regulatory component activity' B iff :A and B are GO molecular functions (GO_0003674), A has_component B and A is positively regulated by B." ;
rdfs:range xsd:string ;
rdfs:subPropertyOf obo:RO_0002336 , obo:RO_0002013 .
obo:RO_0002017 a rdf:Property ;
rdfs:label "has component activity" ;
rdfs:range xsd:string ;
rdfs:subPropertyOf obo:RO_0002018 .
obo:RO_0002022 a rdf:Property ;
rdfs:label "directly regulated by" ;
rdfs:range xsd:string ;
rdfs:subPropertyOf obo:RO_0002334 .
obo:RO_0002023 a rdf:Property ;
rdfs:label "directly negatively regulated by" ;
rdfs:comment "Process(P2) is directly negatively regulated by process(P1) iff: P1 negatively regulates P2 via direct physical interaction between an agent executing P1 (or some part of P1) and an agent executing P2 (or some part of P2). For example, if protein A has protein binding activity(P1) that targets protein B and this binding negatively regulates the kinase activity (P2) of protein B then P2 directly negatively regulated by P1." ;
rdfs:range xsd:string ;
rdfs:subPropertyOf obo:RO_0002022 .
obo:RO_0002024 a rdf:Property ;
rdfs:label "directly positively regulated by" ;
rdfs:comment "Process(P2) is directly postively regulated by process(P1) iff: P1 positively regulates P2 via direct physical interaction between an agent executing P1 (or some part of P1) and an agent executing P2 (or some part of P2). For example, if protein A has protein binding activity(P1) that targets protein B and this binding positively regulates the kinase activity (P2) of protein B then P2 is directly postively regulated by P1." ;
rdfs:range xsd:string ;
rdfs:subPropertyOf obo:RO_0002022 .
obo:RO_0002025 a rdf:Property ;
rdfs:label "has effector activity" ;
rdfs:comment "A 'has effector activity' B if A and B are GO molecular functions (GO_0003674), A 'has component activity' B and B is the effector (output function) of B. Each compound function has only one effector activity." ;
rdfs:range xsd:string ;
rdfs:subPropertyOf obo:RO_0002017 .
obo:RO_0002086 a rdf:Property ;
rdfs:label "ends after"@en ;
rdfs:range xsd:string ;
rdfs:subPropertyOf obo:RO_0002222 .
obo:RO_0002087 a rdf:Property ;
rdfs:label "immediately preceded by"@en ;
rdfs:range xsd:string ;
rdfs:subPropertyOf obo:BFO_0000062 .
obo:RO_0002090 a rdf:Property ;
rdfs:label "immediately precedes"@en ;
rdfs:range xsd:string ;
rdfs:subPropertyOf obo:BFO_0000063 .
obo:RO_0002131 a rdf:Property ;
rdfs:label "overlaps"@en ;
rdfs:comment "x overlaps y if and only if there exists some z such that x has part z and z part of y" ;
rdfs:range xsd:string ;
rdfs:subPropertyOf obo:RO_0002323 .
obo:RO_0002180 a rdf:Property ;
rdfs:label "has component"@en ;
rdfs:comment "w 'has component' p if w 'has part' p and w is such that it can be directly disassembled into into n parts p, p2, p3, ..., pn, where these parts are of similar type." ;
rdfs:range xsd:string ;
rdfs:subPropertyOf obo:BFO_0000051 .
obo:RO_0002212 a rdf:Property ;
rdfs:label "negatively regulates"@en ;
rdfs:comment "p negatively regulates q iff p regulates q, and p decreases the rate or magnitude of execution of q." ;
rdfs:range xsd:string ;
rdfs:subPropertyOf obo:RO_0002305 , obo:RO_0002211 .
obo:RO_0002213 a rdf:Property ;
rdfs:label "positively regulates"@en ;
rdfs:comment "p positively regulates q iff p regulates q, and p increases the rate or magnitude of execution of q." ;
rdfs:range xsd:string ;
rdfs:subPropertyOf obo:RO_0002304 , obo:RO_0002211 .
obo:RO_0002216 a rdf:Property ;
rdfs:label "capable of part of"@en ;
rdfs:comment "c stands in this relationship to p if and only if there exists some p' such that c is capable_of p', and p' is part_of p." ;
rdfs:range xsd:string ;
rdfs:subPropertyOf obo:RO_0002500 , obo:RO_0002328 .
obo:RO_0002263 a rdf:Property ;
rdfs:label "acts upstream of" ;
rdfs:comment "c acts upstream of p if and only if c enables some f that is involved in p' and p' occurs chronologically before p, is not part of p, and affects the execution of p. c is a material entity and f, p, p' are processes." ;
rdfs:range xsd:string ;
rdfs:subPropertyOf obo:RO_0002264 .
obo:RO_0002264 a rdf:Property ;
rdfs:label "acts upstream of or within" ;
rdfs:comment "c acts upstream of or within p if c is enables f, and f is causally upstream of or within p. c is a material entity and p is an process." ;
rdfs:range xsd:string ;
rdfs:subPropertyOf obo:RO_0002500 .
obo:RO_0002304 a rdf:Property ;
rdfs:label "causally upstream of, positive effect" ;
rdfs:comment "p is causally upstream of, positive effect q iff p is casually upstream of q, and the execution of p is required for the execution of q." ;
rdfs:range xsd:string ;
rdfs:subPropertyOf obo:RO_0004047 , obo:RO_0002411 .
obo:RO_0002305 a rdf:Property ;
rdfs:label "causally upstream of, negative effect" ;
rdfs:comment "p is causally upstream of, negative effect q iff p is casually upstream of q, and the execution of p decreases the execution of q." ;
rdfs:range xsd:string ;
rdfs:subPropertyOf obo:RO_0004046 , obo:RO_0002411 .
obo:RO_0002314 a rdf:Property ;
rdfs:label "characteristic of part of"@en ;
rdfs:comment "q characteristic of part of w if and only if there exists some p such that q inheres in p and p part of w." ;
rdfs:range xsd:string ;
rdfs:subPropertyOf obo:RO_0002502 .
obo:RO_0002323 a rdf:Property ;
rdfs:label "mereotopologically related to"@en ;
rdfs:comment "A mereological relationship or a topological relationship" ;
rdfs:range .
obo:RO_0002327 a rdf:Property ;
rdfs:label "enables"@en ;
rdfs:comment "c enables p iff c is capable of p and c acts to execute p." ;
rdfs:range xsd:string ;
rdfs:subPropertyOf obo:RO_0002215 .
obo:RO_0002328 a rdf:Property ;
rdfs:label "functionally related to"@en ;
rdfs:comment "A grouping relationship for any relationship directly involving a function, or that holds because of a function of one of the related entities." ;
rdfs:range .
obo:RO_0002329 a rdf:Property ;
rdfs:label "part of structure that is capable of"@en ;
rdfs:comment "this relation holds between c and p when c is part of some c', and c' is capable of p." ;
rdfs:range xsd:string ;
rdfs:subPropertyOf obo:RO_0002328 .
obo:RO_0002331 a rdf:Property ;
rdfs:label "involved in"@en ;
rdfs:comment "c involved_in p if and only if c enables some process p', and p' is part of p" ;
rdfs:range xsd:string ;
rdfs:subPropertyOf obo:RO_0002431 , obo:RO_0000056 .
obo:RO_0002333 a rdf:Property ;
rdfs:label "enabled by"@en ;
rdfs:comment "inverse of enables" ;
rdfs:range xsd:string ;
rdfs:subPropertyOf obo:RO_0002328 , obo:RO_0000057 .
obo:RO_0002335 a rdf:Property ;
rdfs:label "negatively regulated by"@en ;
rdfs:comment "inverse of negatively regulates" ;
rdfs:range xsd:string ;
rdfs:subPropertyOf obo:RO_0002334 .
obo:RO_0002336 a rdf:Property ;
rdfs:label "positively regulated by"@en ;
rdfs:comment "inverse of positively regulates" ;
rdfs:range xsd:string ;
rdfs:subPropertyOf obo:RO_0002334 .
obo:RO_0002352 a rdf:Property ;
rdfs:label "input of"@en ;
rdfs:comment "inverse of has input" ;
rdfs:range xsd:string ;
rdfs:subPropertyOf obo:RO_0002328 , obo:RO_0000056 .
obo:RO_0002379 a rdf:Property ;
rdfs:label "spatially coextensive with"@en ;
rdfs:comment "x spatially_coextensive_with y if and inly if x and y have the same location" ;
rdfs:range xsd:string ;
rdfs:subPropertyOf obo:RO_0002131 .
obo:RO_0002404 a rdf:Property ;
rdfs:label "causally downstream of"@en ;
rdfs:comment "inverse of upstream of" ;
rdfs:range xsd:string ;
rdfs:subPropertyOf obo:RO_0002427 , obo:BFO_0000062 .
obo:RO_0002405 a rdf:Property ;
rdfs:label "immediately causally downstream of"@en ;
rdfs:range xsd:string ;
rdfs:subPropertyOf obo:RO_0002404 , obo:RO_0002087 .
obo:RO_0002407 a rdf:Property ;
rdfs:label "indirectly positively regulates"@en ;
rdfs:comment "p indirectly positively regulates q iff p is indirectly causally upstream of q and p positively regulates q." ;
rdfs:range xsd:string ;
rdfs:subPropertyOf obo:RO_0012012 , obo:RO_0002213 .
obo:RO_0002409 a rdf:Property ;
rdfs:label "indirectly negatively regulates"@en ;
rdfs:comment "p indirectly negatively regulates q iff p is indirectly causally upstream of q and p negatively regulates q." ;
rdfs:range xsd:string ;
rdfs:subPropertyOf obo:RO_0012012 , obo:RO_0002212 .
obo:RO_0002410 a rdf:Property ;
rdfs:label "causally related to"@en ;
rdfs:comment "relation that links two events, processes, states, or objects such that one event, process, state, or object (a cause) contributes to the production of another event, process, state, or object (an effect) where the cause is partly or wholly responsible for the effect, and the effect is partly or wholly dependent on the cause." ;
rdfs:range .
obo:RO_0002411 a rdf:Property ;
rdfs:label "causally upstream of"@en ;
rdfs:comment "p is causally upstream of q iff p is causally related to q, the end of p precedes the end of q, and p is not an occurrent part of q." ;
rdfs:range xsd:string ;
rdfs:subPropertyOf obo:RO_0002418 , obo:BFO_0000063 .
obo:RO_0002412 a rdf:Property ;
rdfs:label "immediately causally upstream of"@en ;
rdfs:comment "p is immediately causally upstream of q iff p is causally upstream of q, and the end of p is coincident with the beginning of q." ;
rdfs:range xsd:string ;
rdfs:subPropertyOf obo:RO_0002411 , obo:RO_0002090 .
obo:RO_0002418 a rdf:Property ;
rdfs:label "causally upstream of or within" ;
rdfs:comment "p is 'causally upstream or within' q iff p is causally related to q, and the end of p precedes, or is coincident with, the end of q." ;
rdfs:range xsd:string ;
rdfs:subPropertyOf obo:RO_0002501 .
obo:RO_0002427 a rdf:Property ;
rdfs:label "causally downstream of or within" ;
rdfs:comment "inverse of causally upstream of or within" ;
rdfs:range xsd:string ;
rdfs:subPropertyOf obo:RO_0002501 .
obo:RO_0002428 a rdf:Property ;
rdfs:label "involved in regulation of" ;
rdfs:comment "c involved in regulation of p if c is involved in some p' and p' regulates some p" ;
rdfs:range xsd:string ;
rdfs:subPropertyOf obo:RO_0002431 , obo:RO_0002263 .
obo:RO_0002429 a rdf:Property ;
rdfs:label "involved in positive regulation of" ;
rdfs:comment "c involved in regulation of p if c is involved in some p' and p' positively regulates some p" ;
rdfs:range xsd:string ;
rdfs:subPropertyOf obo:RO_0002428 .
obo:RO_0002430 a rdf:Property ;
rdfs:label "involved in negative regulation of" ;
rdfs:comment "c involved in regulation of p if c is involved in some p' and p' negatively regulates some p" ;
rdfs:range xsd:string ;
rdfs:subPropertyOf obo:RO_0002428 .
obo:RO_0002431 a rdf:Property ;
rdfs:label "involved in or involved in regulation of" ;
rdfs:comment "c involved in or regulates p if and only if either (i) c is involved in p or (ii) c is involved in regulation of p" ;
rdfs:range xsd:string ;
rdfs:subPropertyOf obo:RO_0002328 , obo:RO_0002500 , obo:RO_0002264 .
obo:RO_0002436 a rdf:Property ;
rdfs:label "molecularly interacts with" ;
rdfs:comment "An interaction relationship in which the two partners are molecular entities that directly physically interact with each other for example via a stable binding interaction or a brief interaction during which one modifies the other." ;
rdfs:range xsd:string ;
rdfs:subPropertyOf obo:RO_0002434 .
obo:RO_0002447 a rdf:Property ;
rdfs:label "phosphorylates" ;
rdfs:range xsd:string ;
rdfs:subPropertyOf obo:RO_0002436 .
obo:RO_0002464 a rdf:Property ;
rdfs:label "helper property (not for use in curation)" ;
rdfs:range .
obo:RO_0002481 a rdf:Property ;
rdfs:label "is kinase activity" ;
rdfs:range xsd:string ;
rdfs:subPropertyOf obo:RO_0002564 .
obo:RO_0002500 a rdf:Property ;
rdfs:label "causal agent in process" ;
rdfs:comment "A relationship between a material entity and a process where the material entity has some causal role that influences the process" ;
rdfs:range xsd:string ;
rdfs:subPropertyOf obo:RO_0002595 .
obo:RO_0002502 a rdf:Property ;
rdfs:label "depends on" ;
rdfs:range .
obo:RO_0002559 a rdf:Property ;
rdfs:label "causally influenced by" ;
rdfs:range xsd:string ;
rdfs:subPropertyOf obo:RO_0002506 .
obo:RO_0002563 a rdf:Property ;
rdfs:label "interaction relation helper property" ;
rdfs:range xsd:string ;
rdfs:subPropertyOf obo:RO_0002464 .
obo:RO_0002564 a rdf:Property ;
rdfs:label "molecular interaction relation helper property" ;
rdfs:range xsd:string ;
rdfs:subPropertyOf obo:RO_0002563 .
obo:RO_0002578 a rdf:Property ;
rdfs:label "directly regulates" ;
rdfs:comment "p directly regulates q iff p is immediately causally upstream of q and p regulates q." ;
rdfs:range xsd:string ;
rdfs:subPropertyOf obo:RO_0002412 , obo:RO_0002211 .
obo:RO_0002584 a rdf:Property ;
rdfs:label "has part structure that is capable of" ;
rdfs:comment "s 'has part structure that is capable of' p if and only if there exists some part x such that s 'has part' x and x 'capable of' p" ;
rdfs:range xsd:string ;
rdfs:subPropertyOf obo:RO_0002595 , obo:RO_0002328 .
obo:RO_0002596 a rdf:Property ;
rdfs:label "capable of regulating" ;
rdfs:comment "Holds between c and p if and only if c is capable of some activity a, and a regulates p." ;
rdfs:range xsd:string ;
rdfs:subPropertyOf obo:RO_0002500 .
obo:RO_0002597 a rdf:Property ;
rdfs:label "capable of negatively regulating" ;
rdfs:comment "Holds between c and p if and only if c is capable of some activity a, and a negatively regulates p." ;
rdfs:range xsd:string ;
rdfs:subPropertyOf obo:RO_0002596 .
obo:RO_0002598 a rdf:Property ;
rdfs:label "capable of positively regulating" ;
rdfs:comment "Holds between c and p if and only if c is capable of some activity a, and a positively regulates p." ;
rdfs:range xsd:string ;
rdfs:subPropertyOf obo:RO_0002596 .
obo:RO_0002608 a rdf:Property ;
rdfs:label "process has causal agent" ;
rdfs:comment "Inverse of 'causal agent in process'" ;
rdfs:range xsd:string ;
rdfs:subPropertyOf obo:RO_0002410 .
obo:RO_0002629 a rdf:Property ;
rdfs:label "directly positively regulates" ;
rdfs:comment "p directly positively regulates q iff p is immediately causally upstream of q, and p positively regulates q." ;
rdfs:range xsd:string ;
rdfs:subPropertyOf obo:RO_0002578 , obo:RO_0002213 .
obo:RO_0002630 a rdf:Property ;
rdfs:label "directly negatively regulates" ;
rdfs:comment "p directly negatively regulates q iff p is immediately causally upstream of q, and p negatively regulates q." ;
rdfs:range xsd:string ;
rdfs:subPropertyOf obo:RO_0002578 , obo:RO_0002212 .
obo:RO_0004031 a rdf:Property ;
rdfs:label "enables subfunction" ;
rdfs:comment "Holds between an entity and an process P where the entity enables some larger compound process, and that larger process has-part P." ;
rdfs:range xsd:string ;
rdfs:subPropertyOf obo:RO_0002328 .
obo:RO_0004032 a rdf:Property ;
rdfs:label "acts upstream of or within, positive effect" ;
rdfs:range xsd:string ;
rdfs:subPropertyOf obo:RO_0002264 .
obo:RO_0004033 a rdf:Property ;
rdfs:label "acts upstream of or within, negative effect" ;
rdfs:range xsd:string ;
rdfs:subPropertyOf obo:RO_0002264 .
obo:RO_0004034 a rdf:Property ;
rdfs:label "acts upstream of, positive effect" ;
rdfs:comment "c 'acts upstream of, positive effect' p if c is enables f, and f is causally upstream of p, and the direction of f is positive" ;
rdfs:range xsd:string ;
rdfs:subPropertyOf obo:RO_0004032 , obo:RO_0002263 .
obo:RO_0004035 a rdf:Property ;
rdfs:label "acts upstream of, negative effect" ;
rdfs:comment "c 'acts upstream of, negative effect' p if c is enables f, and f is causally upstream of p, and the direction of f is negative" ;
rdfs:range xsd:string ;
rdfs:subPropertyOf obo:RO_0004033 , obo:RO_0002263 .
obo:RO_0004046 a rdf:Property ;
rdfs:label "causally upstream of or within, negative effect" ;
rdfs:range xsd:string ;
rdfs:subPropertyOf obo:RO_0002418 .
obo:RO_0004047 a rdf:Property ;
rdfs:label "causally upstream of or within, positive effect" ;
rdfs:range xsd:string ;
rdfs:subPropertyOf obo:RO_0002418 .
obo:RO_0012011 a rdf:Property ;
rdfs:label "indirectly causally upstream of"@en ;
rdfs:comment "p is indirectly causally upstream of q iff p is causally upstream of q and there exists some process r such that p is causally upstream of r and r is causally upstream of q." ;
rdfs:range xsd:string ;
rdfs:subPropertyOf obo:RO_0002411 .
obo:RO_0012012 a rdf:Property ;
rdfs:label "indirectly regulates"@en ;
rdfs:comment "p indirectly regulates q iff p is indirectly causally upstream of q and p regulates q." ;
rdfs:range xsd:string ;
rdfs:subPropertyOf obo:RO_0012011 , obo:RO_0002211 .
obo:RO_0017001 a rdf:Property ;
rdfs:label "device utilizes material"@en ;
rdfs:comment "X device utilizes material Y means X and Y are material entities, and X is capable of some process P that has input Y." ;
rdfs:range .
obo:RO_0019001 a rdf:Property ;
rdfs:label "positively regulates characteristic" ;
rdfs:comment "A relationship that holds between a process and a characteristic in which process (P) positively regulates characteristic (C) iff: P results in an increase in the intensity or magnitude of C." ;
rdfs:range xsd:string ;
rdfs:subPropertyOf obo:RO_0019000 .
obo:RO_0019002 a rdf:Property ;
rdfs:label "negatively regulates characteristic" ;
rdfs:comment "A relationship that holds between a process and a characteristic in which process (P) negatively regulates characteristic (C) iff: P results in a decrease in the intensity or magnitude of C." ;
rdfs:range xsd:string ;
rdfs:subPropertyOf obo:RO_0019000 .
obo:RO_0019009 a rdf:Property ;
rdfs:label "component of" ;
rdfs:comment "Inverse of 'has component'." ;
rdfs:range xsd:string ;
rdfs:subPropertyOf obo:BFO_0000050 .
a rdf:Property ;
rdfs:range xsd:string .
a rdf:Property ;
rdfs:range xsd:string .
a rdf:Property ;
rdfs:range xsd:string .
a rdf:Property ;
rdfs:range xsd:string .
a rdf:Property ;
rdfs:range xsd:string .
a rdf:Property ;
rdfs:range xsd:string .
a rdf:Property ;
rdfs:range xsd:string .
a rdf:Property ;
rdfs:range xsd:string .
a rdf:Property ;
rdfs:range xsd:string .
a rdf:Property ;
rdfs:label "EGA_subset" ;
rdfs:comment "The cohorts that studies in the European Genome-phenome Archive (EGA) draw on."@en ;
rdfs:range xsd:string .
a rdf:Property ;
rdfs:label "GEC_subset" ;
rdfs:comment "The cohorts listed in the Global Exposome Cohort Catalogue, the Global Exposome Cohorts network of the MOLGENIS catalogue."@en ;
rdfs:range xsd:string .
a rdf:Property ;
rdfs:label "GWAS_subset" ;
rdfs:comment "The cohorts that studies in the GWAS Catalog draw on."@en ;
rdfs:range xsd:string .
a rdf:Property ;
rdfs:label "IHCC_subset" ;
rdfs:comment "The cohorts listed in the IHCC Cohort Atlas, the International Health Cohorts Consortium's directory of its member cohorts."@en ;
rdfs:range xsd:string .
a rdf:Property ;
rdfs:label "MetaboLight_subset" ;
rdfs:comment "The cohorts that studies in MetaboLights draw on."@en ;
rdfs:range xsd:string .
a rdf:Property ;
rdfs:label "PGS_subset" ;
rdfs:comment "The cohorts that scores in the PGS Catalog draw on."@en ;
rdfs:range xsd:string .
a rdf:Property ;
rdfs:label "PRIDE_subset" ;
rdfs:comment "The cohorts that datasets in the PRIDE proteomics archive draw on."@en ;
rdfs:range xsd:string .
a rdf:Property ;
rdfs:label "has_data_collection_location"@en ;
rdfs:comment "A relation between a cohort and a geographical area in which its participants were recruited. Where the data were analysed or are stored does not count."@en ;
rdfs:range obo:NCIT_C16632 .
a rdf:Property ;
rdfs:label "has_participants_at_risk_of"@en ;
rdfs:comment "A relation between a cohort and a disease its participants were selected for their risk of: relatives of patients, carriers of a mutation, people with a pre-disease state, or a group chosen for its high risk of the disease."@en ;
rdfs:range xsd:string ;
rdfs:subPropertyOf .
a rdf:Property ;
rdfs:label "has_participants_with_exposure"@en ;
rdfs:comment "A relation between a cohort and an environmental exposure its participants were selected for, or are followed for: residents of a contaminated or disaster area, survivors of an event, workers in an industry or trade, smokers recruited as smokers, veterans of a deployment, or a birth cohort exposed to a famine."@en ;
rdfs:range xsd:string ;
rdfs:subPropertyOf .
a rdf:Property ;
rdfs:label "has_patients_with"@en ;
rdfs:comment "A relation between a cohort and a disease its participants have: a patient series, a disease registry, the cases of a case-control study, the participants of a trial of the condition, or a biobank of patients with the disease."@en ;
rdfs:range xsd:string ;
rdfs:subPropertyOf .
a rdf:Property ;
rdfs:label "is_designed_to_study_exposure"@en ;
rdfs:comment "A relation between a cohort and an environmental exposure that its stated purpose or design centres on measuring, with its effects, its participants not being selected for the exposure: an exposome cohort, a birth cohort built around prenatal exposure to a pollutant, an air pollution cohort, a diet and cancer cohort, or an occupational health cohort."@en ;
rdfs:range xsd:string ;
rdfs:subPropertyOf .
a rdf:Property ;
rdfs:label "is_population_study_of"@en ;
rdfs:comment "A relation between a cohort and a disease, or a family of diseases, that a general population or birth cohort was set up to study, its participants not being selected for having the disease or for their risk of it."@en ;
rdfs:range xsd:string ;
rdfs:subPropertyOf .
a rdf:Property ;
rdfs:label "numberOfCases"@en ;
rdfs:comment "The number of cases a cohort reports, as its own design or profile paper or website states it: the participants with the condition under study in a case-control study. It is the number a source states, never one derived; the assertion carries that source, the sentence stating the number and what it counts. Asserted beside numberOfParticipants, or instead of it where no source states a total."@en ;
rdfs:range xsd:integer .
a rdf:Property ;
rdfs:label "numberOfControls"@en ;
rdfs:comment "The number of controls a cohort reports, as its own design or profile paper or website states it: the participants without the condition under study in a case-control study. It is the number a source states, never one derived; the assertion carries that source, the sentence stating the number and what it counts. Asserted beside numberOfParticipants, or instead of it where no source states a total."@en ;
rdfs:range xsd:integer .
a rdf:Property ;
rdfs:label "numberOfParticipants"@en ;
rdfs:comment "The number of participants a cohort reports: the people it enrolled or recruited, as its own design or profile paper or website states them, or, for a cohort aggregation, the pooled number of participants in its main analysis. It is the number a source states, never one computed, summed or inferred; the assertion carries that source, the sentence stating the number and what it counts. A definition never gives a size."@en ;
rdfs:range xsd:integer .
obo:IAO_0000078 a rdfs:Class ;
rdfs:label "curation status specification"@en ;
rdfs:comment "The curation status of the term. The allowed values come from an enumerated list of predefined terms. See the specification of these instances for more detailed definitions of each enumerated value."@en ;
rdfs:subClassOf obo:IAO_0000102 .
obo:IAO_0000002 a obo:IAO_0000078 ;
rdfs:label "example to be eventually removed"@en .
obo:IAO_0000120 a obo:IAO_0000078 ;
rdfs:label "metadata complete"@en ;
rdfs:comment "Class has all its metadata, but is either not guaranteed to be in its final location in the asserted IS_A hierarchy or refers to another class that is not complete."@en .
obo:IAO_0000121 a obo:IAO_0000078 ;
rdfs:label "organizational term"@en ;
rdfs:comment "The term was created to ease viewing/sorting terms for development purposes, but will not be included in a release."@en .
obo:IAO_0000122 a obo:IAO_0000078 ;
rdfs:label "ready for release"@en ;
rdfs:comment "Class has undergone final review, is ready for use, and will be included in the next release. Any class lacking \"ready_for_release\" should be considered likely to change place in hierarchy, have its definition refined, or be obsoleted in the next release. Those classes deemed \"ready_for_release\" will also derived from a chain of ancestor classes that are also \"ready_for_release.\""@en .
obo:IAO_0000123 a obo:IAO_0000078 ;
rdfs:label "metadata incomplete"@en ;
rdfs:comment "Class is being worked on; however, the metadata (including definition) are not complete or sufficiently clear to the branch editors."@en .
obo:IAO_0000124 a obo:IAO_0000078 ;
rdfs:label "uncurated"@en ;
rdfs:comment "Nothing done yet beyond assigning a unique class ID and proposing a preferred term."@en .
obo:IAO_0000125 a obo:IAO_0000078 ;
rdfs:label "pending final vetting"@en ;
rdfs:comment "All definitions, placement in the asserted IS_A hierarchy and required minimal metadata are complete. The class is awaiting a final review by someone other than the term editor."@en .
obo:IAO_0000423 a obo:IAO_0000078 ;
rdfs:label "to be replaced with external ontology term"@en ;
rdfs:comment "Terms with this status should eventually replaced with a term from another ontology."@en .
obo:IAO_0000428 a obo:IAO_0000078 ;
rdfs:label "requires discussion"@en ;
rdfs:comment "A term that is metadata complete, has been reviewed, and problems have been identified that require discussion before release. Such a term requires editor note(s) to identify the outstanding issues."@en .
obo:IAO_0000225 a rdfs:Class ;
rdfs:label "obsolescence reason specification"@en ;
rdfs:comment "The reason for which a term has been deprecated. The allowed values come from an enumerated list of predefined terms. See the specification of these instances for more detailed definitions of each enumerated value."@en ;
rdfs:subClassOf obo:IAO_0000102 .
obo:IAO_0000103 a obo:IAO_0000225 ;
rdfs:label "failed exploratory term"@en ;
rdfs:comment "The term was initially used in an attempt to structure part of the ontology, but in retrospect failed to do a good job."@en .
obo:IAO_0000226 a obo:IAO_0000225 ;
rdfs:label "placeholder removed"@en ;
rdfs:comment "The term was created to temporarily stand in for a semantic purpose, but is no longer needed, typically due to another permanent term being defined."@en .
obo:IAO_0000227 a obo:IAO_0000225 ;
rdfs:label "terms merged"@en ;
rdfs:comment "The term has been combined with one or more other terms to create a more encompassing (merged) term."@en .
obo:IAO_0000228 a obo:IAO_0000225 ;
rdfs:label "term imported"@en ;
rdfs:comment "The term has been replaced by a term imported from another ontology."@en .
obo:IAO_0000229 a obo:IAO_0000225 ;
rdfs:label "term split"@en ;
rdfs:comment "The term has been split into two or more new terms."@en .
obo:OMO_0001000 a obo:IAO_0000225 ;
rdfs:label "out of scope" ;
rdfs:comment "The term was added to the ontology on the assumption it was in scope, but it turned out later that it was not."@en .
obo:IAO_0000409 a rdfs:Class ;
rdfs:label "denotator type"@en ;
rdfs:comment "A denotator type indicates how a term should be interpreted from an ontological perspective."@en ;
rdfs:subClassOf obo:IAO_0000102 .
obo:IAO_0000410 a obo:IAO_0000409 ;
rdfs:label "universal"@en .
obo:IAO_0000420 a obo:IAO_0000409 ;
rdfs:label "defined class"@en ;
rdfs:comment "A defined class is a class that is defined by a set of logically necessary and sufficient conditions but is not a universal"@en .
obo:IAO_0000421 a obo:IAO_0000409 ;
rdfs:label "named class expression"@en ;
rdfs:comment "A named class expression is a logical expression that is given a name. The name can be used in place of the expression."@en .
obo:NCIT_C25464 a rdfs:Class ;
rdfs:label "Country" ;
rdfs:subClassOf obo:NCIT_C16632 .
a obo:NCIT_C25464 ;
rdfs:label "Nigeria" .
a obo:NCIT_C25464 ;
rdfs:label "Bangladesh" .
a obo:NCIT_C25464 ;
rdfs:label "Lithuania" .
a obo:NCIT_C25464 ;
rdfs:label "Palestinian territories" .
a obo:NCIT_C25464 ;
rdfs:label "Netherlands" .
a obo:NCIT_C25464 ;
rdfs:label "Zimbabwe" .
a obo:NCIT_C25464 ;
rdfs:label "Indonesia" .
a obo:NCIT_C25464 ;
rdfs:label "Cameroon" .
a obo:NCIT_C25464 ;
rdfs:label "Brazil" .
a obo:NCIT_C25464 ;
rdfs:label "Canada" .
a obo:NCIT_C25464 ;
rdfs:label "Cyprus" .
a obo:NCIT_C25464 ;
rdfs:label "Azerbaijan" .
a obo:NCIT_C25464 ;
rdfs:label "Ecuador" .
a obo:NCIT_C25464 ;
rdfs:label "France" .
a obo:NCIT_C25464 ;
rdfs:label "Saudi Arabia" .
a obo:NCIT_C25464 ;
rdfs:label "South Africa" .
a obo:NCIT_C25464 ;
rdfs:label "Greece" .
a obo:NCIT_C25464 ;
rdfs:label "Guinea" .
a obo:NCIT_C25464 ;
rdfs:label "Malaysia" .
a obo:NCIT_C25464 ;
rdfs:label "Jamaica" .
a obo:NCIT_C25464 ;
rdfs:label "Israel" .
a obo:NCIT_C25464 ;
rdfs:label "Chile" .
a obo:NCIT_C25464 ;
rdfs:label "China" .
a obo:NCIT_C25464 ;
rdfs:label "Egypt" .
a obo:NCIT_C25464 ;
rdfs:label "Philippines" .
a obo:NCIT_C25464 ;
rdfs:label "Ghana" .
a obo:NCIT_C25464 ;
rdfs:label "Haiti" .
a obo:NCIT_C25464 ;
rdfs:label "India" .
a obo:NCIT_C25464 ;
rdfs:label "Italy" .
a obo:NCIT_C25464 ;
rdfs:label "Japan" .
a obo:NCIT_C25464 ;
rdfs:label "Kenya" .
a obo:NCIT_C25464 ;
rdfs:label "Malta" .
a obo:NCIT_C25464 ;
rdfs:label "Qatar" .
a obo:NCIT_C25464 ;
rdfs:label "Spain" .
a obo:NCIT_C25464 ;
rdfs:label "Sudan" .
a obo:NCIT_C25464 ;
rdfs:label "Kuwait" .
a obo:NCIT_C25464 ;
rdfs:label "Latvia" .
a obo:NCIT_C25464 ;
rdfs:label "Guatemala" .
a obo:NCIT_C25464 ;
rdfs:label "Malawi" .
a obo:NCIT_C25464 ;
rdfs:label "Mexico" .
a obo:NCIT_C25464 ;
rdfs:label "Saint Lucia" .
a obo:NCIT_C25464 ;
rdfs:label "Norway" .
a obo:NCIT_C25464 ;
rdfs:label "Panama" .
a obo:NCIT_C25464 ;
rdfs:label "Poland" .
a obo:NCIT_C25464 ;
rdfs:label "Russia" .
a obo:NCIT_C25464 ;
rdfs:label "Serbia" .
a obo:NCIT_C25464 ;
rdfs:label "Sweden" .
a obo:NCIT_C25464 ;
rdfs:label "Taiwan" .
a obo:NCIT_C25464 ;
rdfs:label "Turkey" .
a obo:NCIT_C25464 ;
rdfs:label "Tuvalu" .
a obo:NCIT_C25464 ;
rdfs:label "Uganda" .
a obo:NCIT_C25464 ;
rdfs:label "Estonia" .
a obo:NCIT_C25464 ;
rdfs:label "Kazakhstan" .
a obo:NCIT_C25464 ;
rdfs:label "Zambia" .
a obo:NCIT_C25464 ;
rdfs:label "Mozambique" .
a obo:NCIT_C25464 ;
rdfs:label "North Macedonia" .
a obo:NCIT_C25464 ;
rdfs:label "Portugal" .
a obo:NCIT_C25464 ;
rdfs:label "Pakistan" .
a obo:NCIT_C25464 ;
rdfs:label "Thailand" .
a obo:NCIT_C25464 ;
rdfs:label "Uzbekistan" .
a obo:NCIT_C25464 ;
rdfs:label "Finland" .
a obo:NCIT_C25464 ;
rdfs:label "Dominican Republic" .
a obo:NCIT_C25464 ;
rdfs:label "Georgia" .
a obo:NCIT_C25464 ;
rdfs:label "Armenia" .
a obo:NCIT_C25464 ;
rdfs:label "Liechtenstein" .
a obo:NCIT_C25464 ;
rdfs:label "Sri Lanka" .
a obo:NCIT_C25464 ;
rdfs:label "Australia" .
a obo:NCIT_C25464 ;
rdfs:label "Austria" .
a obo:NCIT_C25464 ;
rdfs:label "South Korea" .
a obo:NCIT_C25464 ;
rdfs:label "Ukraine" .
a obo:NCIT_C25464 ;
rdfs:label "Belarus" .
a obo:NCIT_C25464 ;
rdfs:label "Belgium" .
a obo:NCIT_C25464 ;
rdfs:label "Ivory Coast" .
a obo:NCIT_C25464 ;
rdfs:label "Uruguay" .
a obo:NCIT_C25464 ;
rdfs:label "Germany" .
a obo:NCIT_C25464 ;
rdfs:label "Lebanon" .
a obo:NCIT_C25464 ;
rdfs:label "United Kingdom" .
a obo:NCIT_C25464 ;
rdfs:label "Guinea-Bissau" .
a obo:NCIT_C25464 ;
rdfs:label "Argentina" .
a obo:NCIT_C25464 ;
rdfs:label "Botswana" .
a obo:NCIT_C25464 ;
rdfs:label "Mauritius" .
a obo:NCIT_C25464 ;
rdfs:label "Vietnam" .
a obo:NCIT_C25464 ;
rdfs:label "Democratic Republic of the Congo" .
a obo:NCIT_C25464 ;
rdfs:label "Cuba" .
a obo:NCIT_C25464 ;
rdfs:label "Iran" .
a obo:NCIT_C25464 ;
rdfs:label "Peru" .
a obo:NCIT_C25464 ;
rdfs:label "Barbados" .
a obo:NCIT_C25464 ;
rdfs:label "Costa Rica" .
a obo:NCIT_C25464 ;
rdfs:label "Burkina Faso" .
a obo:NCIT_C25464 ;
rdfs:label "New Zealand" .
a obo:NCIT_C25464 ;
rdfs:label "Ethiopia" .
a obo:NCIT_C25464 ;
rdfs:label "Guernsey" .
a obo:NCIT_C25464 ;
rdfs:label "Bulgaria" .
a obo:NCIT_C25464 ;
rdfs:label "Croatia" .
a obo:NCIT_C25464 ;
rdfs:label "Luxembourg" .
a obo:NCIT_C25464 ;
rdfs:label "United States" .
a obo:NCIT_C25464 ;
rdfs:label "Republic of Ireland" .
a obo:NCIT_C25464 ;
rdfs:label "Singapore" .
a obo:NCIT_C25464 ;
rdfs:label "Moldova" .
a obo:NCIT_C25464 ;
rdfs:label "Hungary" .
a obo:NCIT_C25464 ;
rdfs:label "Slovakia" .
a obo:NCIT_C25464 ;
rdfs:label "Slovenia" .
a obo:NCIT_C25464 ;
rdfs:label "Romania" .
a obo:NCIT_C25464 ;
rdfs:label "Switzerland" .
a obo:NCIT_C25464 ;
rdfs:label "Hong Kong" .
a obo:NCIT_C25464 ;
rdfs:label "United Arab Emirates" .
a obo:NCIT_C25464 ;
rdfs:label "Denmark" .
a obo:NCIT_C25464 ;
rdfs:label "Puerto Rico" .
a obo:NCIT_C25464 ;
rdfs:label "Iceland" .
a obo:NCIT_C25464 ;
rdfs:label "El Salvador" .
a obo:NCIT_C25464 ;
rdfs:label "Venezuela" .
a obo:NCIT_C25464 ;
rdfs:label "Colombia" .
a obo:NCIT_C25464 ;
rdfs:label "Tanzania" .
a obo:NCIT_C25464 ;
rdfs:label "Tajikistan" .
a obo:NCIT_C25464 ;
rdfs:label "Czech Republic" .